The Predictability of Ocean Environments that Contributed to the 2020/21 Extreme Cold Events in China: 2020/21 La Niña and 2020 Arctic Sea Ice Loss - Fei Zheng; Ji-Ping Liu; Xiang-Hui Fang; Mi-Rong Song; Chao-Yuan Yang; Yuan Yuan; Ke-Xin Li; Ji Wang; Jiang Zhu (Advances in Atmospheric Sciences, 2022)
Several consecutive extreme cold events impacted China during the first half of winter 2020/21, breaking the low-temperature records in many cities. How to make accurate climate predictions of extreme cold events is still an urgent issue. The synergistic effect of the warm Arctic and cold tropical Pacific has been demonstrated to intensify the intrusions of cold air from polar regions into middle-high latitudes, further influencing the cold conditions in China. However, climate models failed to predict these two ocean environments at expected lead times. Most seasonal climate forecasts only predicted the 2020/21 La Niña after the signal had already become apparent and significantly underestimated the observed Arctic sea ice loss in autumn 2020 with a 1–2 month advancement. In this work, the corresponding physical factors that may help improve the accuracy of seasonal climate predictions are further explored. For the 2020/21 La Niña prediction, through sensitivity experiments involving different atmospheric–oceanic initial conditions, the predominant southeasterly wind anomalies over the equatorial Pacific in spring of 2020 are diagnosed to play an irreplaceable role in triggering this cold event. A reasonable inclusion of atmospheric surface winds into the initialization will help the model predict La Niña development from the early spring of 2020. For predicting the Arctic sea ice loss in autumn 2020, an anomalously cyclonic circulation from the central Arctic Ocean predicted by the model, which swept abnormally hot air over Siberia into the Arctic Ocean, is recognized as an important contributor to successfully predicting the minimum Arctic sea ice extent.

Sterols and triterpenoids from Ganoderma lucidum and their reversal activities of tumor multidrug resistance - Min Wu; Cui-e Shen; Qiao-fa Lin; Jin-yi Zhong; Yan-fei Zhou; Ben-chen Liu; Jian-hua Xu; Zhi-qiang Zhang; Peng Li (Natural Product Research, 2022)

Decreased peripheral mtDNA in methamphetamine use disorder - Ling-Yan Su; Yuan Li; Qianjin Liu; Lijin Jiao; Jing Shen; Lu-Xiu Yang; Ti-Fei Yuan; Yong-Gang Yao (Science China Life Sciences, 2022)

Forest fire risk estimation in a typical temperate forest in Northeastern China using the Canadian forest fire weather index: case study in autumn 2019 and 2020 - Maombi Mbusa Masinda; Fei Li; Liu Qi; Long Sun; Tongxin Hu (Natural Hazards, 2022)

Integrative analysis of the pharmaceutical active ingredient and transcriptome of the aerial parts of Glycyrrhiza uralensis under salt stress reveals liquiritin accumulation via ABA-mediated signaling - Quan Bi; Hua Yao; Fei Wang; Dajun He; Wenbin Xu; Shuangquan Xie; Xifeng Chen; Yuxia Li; Hailiang Liu; Haitao Shen; Hongbin Li (Molecular Genetics and Genomics, 2022)
The aerial parts of Glycyrrhiza uralensis supply substantial raw material for the extraction of active pharmaceutical ingredients comprehensively utilized in many industries. Our previous study indicated that salt stress increased the content of active ingredients. However, the regulatory mechanism remains unclear. In this study, RNA-sequencing (RNA-seq) of the aerial parts of G. uralensis treated with 150 mM NaCl for 0, 2, 6, and 12 h was performed to identify the key genes and metabolic pathways regulating pharmacological active component accumulation. The main active component detection showed that liquiritin was the major ingredient and exhibited more than a ten-fold significant increase in the 6 h NaCl treatment. Temporal expression analysis of the obtained 4245 differentially expressed genes (DEGs) obtained by RNA-seq revealed two screened profiles that included the significant up-regulated DEGs (UDEGs) at different treatment points. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of these UDEGs identified phenylpropanoid metabolism and flavonoid biosynthesis as the most significantly enriched pathways in 2 h treated materials. Interestingly, the carotenoid biosynthesis pathway that is related to ABA synthesis was also discovered, and the ABA content was significantly promoted after 6 h NaCl treatment. Following ABA stimulation, the content of liquiritin demonstrated a significant and immediate increase after 2 h treatment, with the corresponding consistent expression of genes involved in the pathways of ABA signal transduction and flavonoid biosynthesis, but not in the pathway of glycyrrhizic acid biosynthesis. Our study concludes that salt stress might promote liquiritin accumulation through the ABA-mediated signaling pathway, and provides effective reference for genetic improvement and comprehensive utilization of G. uralensis .

Vermicompost Application Enhances Halophyte Suaeda salsa Performance and Improves Coastal Saline Soil Quality - Jing-Fang Cai; Xuan-Shao Liu; Kai Sun; Fan Jiang; Ming-Xiang Zhang; Hong-Li Li; Fei-Hai Yu (Journal of Soil Science and Plant Nutrition, 2022)

Three kinds of active thin-layer capping materials for reducing the phosphorus load in eutrophic water body: comparison in dynamic experiment - Yichao Wang; Shuwen Li; Shupo Liu; Fei Li; Zhenming Zhou (Environmental Science and Pollution Research, 2022)

Evaluation of a Superabsorbent Polymer for Plugging Karst Pipe Type Water Inrushes - Chenyang Ma; Shucai Li; Rentai Liu; Yan Pei; Chunyu Zhang; Yankai Liu; Fei Xu; Xiao Feng; Mengjun Chen (Mine Water and the Environment, 2022)

Discerning the Putative U and V Chromosomes of Saccharina japonica (Phaeophyta) by Cytogenetic Mapping of Sex-Linked Molecular Markers - Yu Du; Peng-Fei Liu; Zhi Li; Qian Zheng; Yan-Hui Bi; Zhi-Gang Zhou (Frontiers in Marine Science, 2022)
Saccharina japonica , an importantly industrial species in brown seaweeds, has a typical alternate life history of heteromorphic generations and UV sex determination system. But up to now, the sex chromosomes, U and V, in this kelp remain to be evidenced cytologically. In the present study, the female-linked (SJ-f_000170 and MSj68-58-2) and male-linked (SJ-13_001840 and MSj68-16-2) molecular markers developed on the basis of Ectocarpus sex-determining regions (SDRs) were selected after PCR amplification and Southern blotting analysis. Mono-color fluorescence in situ hybridization (FISH) to the kelp metaphase chromosomes with each of these confirmed sex-linked markers as a probe indicated that the hybridization signals were confined to either female or male gametophytes exclusively. The shape and size of hybridized chromosomes and the relative location of these sex-linked markers on them suggested that the marked chromosomes in a sex were the same, which was further confirmed by dual-color FISH observations. SJ-f_000170 and SJ-13_001840, corresponding to each sex, were therefore used to map the sporophyte metaphase chromosomes by dual-color FISH technique, and they were hybridized on different chromosomes as expected. The sporophyte metaphase chromosomes as hybridized by SJ-f_000170 and SJ-13_001840 resembled those in either female or male gametophytes, suggesting that they were the putative U and V, respectively, chromosomes in S . japonica . To further demonstrate the reliability of this inference, genomic information of the screened bacterial artificial chromosome (BAC) clones carrying two female-linked markers, for example, from the constructed BAC libraries of the kelp female gametophytes was provided. The insert sequencing of two selected BAC clones revealed that repetitive elements were rich whereas gene density was poor, which was characterized as non-recombining SDR sequences in brown seaweed Ectocarpus sp. and liverwort Marchantia polymorpha . The present study laid a solid foundation for unveiling the mystery of S . japonica sex chromosomes.

Neoflavonoids from the heartwood of Dalbergia melanoxylon - Meng-fei Wang; Guang-qiang Ma; Feng Shao; Rong-hua Liu; Lan-ying Chen; Yang Liu; Li Yang; Xiao-wei Meng (Natural Product Research, 2022)

Rrn3 gene knockout affects ethanol-induced locomotion in adult heterozygous zebrafish - Fei Li; Jia Lin; Tingting Li; Jing Jian; Qi Zhang; Yinglan Zhang; Xiuyun Liu; Qiang Li (Psychopharmacology, 2022)

Litter nitrogen concentration changes mediate effects of drought and plant species richness on litter decomposition - Jiang Wang; Yuan Ge; Johannes H. C. Cornelissen; Xiao-Yan Wang; Song Gao; Yi Bai; Tong Chen; Zhong-Wang Jing; Chong-Bang Zhang; Wen-Li Liu; Jun-Min Li; Fei-Hai Yu (Oecologia, 2022)

Characterizing the Semi-Volatile Organic Compounds in Runoff from Roads and Other Impervious Surfaces in a Suburban Area of Beijing - Liang Zhang; Haiyan Li; Youshu Wang; Zhichao Yang; Ziyang Zhang; Fei Liu; Linlin Tong; Ying Wang; Yongwei Gong; Hua Yang (Archives of Environmental Contamination and Toxicology, 2022)

Indicator species drive the key ecological functions of microbiota in a river impacted by acid mine drainage generated by rare earth elements mining in South China - Ziwu Chen; Xi Zhong; Mengyuan Zheng; Wen‐Shen Liu; Yingheng Fei; Kengbo Ding; Yaying Li; Ye Liu; Yuanqing Chao; Ye‐Tao Tang; Shizhong Wang; Rongliang Qiu (Environmental Microbiology, 2022)
Summary Acid mine drainage (AMD) generated by rare earth elements (REEs) deposits exploration contains high concentrations of REEs, ammonium and sulfates, which is quite different from typical metallic AMD. Currently, microbial responses and ecological functions in REEs‐AMD impacted rivers are unknown. Here, 16S rRNA analysis and genome‐resolved metagenomics were performed on microbial community collected from a REEs‐AMD contaminated river. The results showed that REEs‐AMD significantly changed river microbial diversity and shaped unique indicator species (e.g. Thaumarchaeota , Methylophilales , Rhodospirillales and Burkholderiales ). The main environmental factors regulating community were pH, ammonium and REEs, among which high concentration of REEs increased REEs‐dependent enzyme‐encoding genes ( XoxF and ExaF / PedH ). Additionally, we reconstructed 566 metagenome‐assembled genomes covering 70.4% of identifying indicators. Genome‐centric analysis revealed that the abundant archaea Thaumarchaeota and Xanthomonadaceae were often involved in nitrification and denitrification, while family Burkholderiaceae were capable of sulfide oxidation coupled with dissimilatory nitrate reduction to ammonium. These indicators play crucial roles in nitrogen and sulfur cycling as well as REEs immobilization in REEs‐AMD contaminated rivers. This study confirmed the potential dual effect of REEs on microbial community at the functional gene level. Our investigation on the ecological roles of indicators further provided new insights for the development of REEs‐AMD bioremediation.

A Novel De Novo TUBB3 Variant Causing Developmental Delay, Epilepsy and Mild Ophthalmological Symptoms in a Chinese Child - Jiao Xue; Zhenfeng Song; Shuyin Ma; Zhi Yi; Chengqing Yang; Fei Li; Kaixuan Liu; Ying Zhang (Journal of Molecular Neuroscience, 2022)

A Facile Probe for Fluorescence Turn-on and Simultaneous Naked-Eyes Discrimination of H2S and biothiols (Cys and GSH) and Its Application - Ting-Ting Liu; Shi-Jie Li; Xiao-Song Zhang; Jing Wang; Yun-Xiu Deng; Xue-Jiao Sun; Zhi-Yong Xing; Ruo-Fei Wu (Journal of Fluorescence, 2022)

Retraction Note to: Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes - Michael Nothnagel; Guangyao Fan; Fei Guo; Yongfeng He; Yiping Hou; Shengping Hu; Jiang Huang; Xianhua Jiang; Wook Kim; Kicheol Kim; Chengtao Li; Hui Li; et al. (Human Genetics, 2022)

Histone methyltransferase DOT1L mediates the TGF-β1/Smad3 signaling pathway through epigenetic modification of SYK in myocardial infarction - Fei Li; Lei Li; Jiacheng Zhang; Xuesong Yang; Yang Liu (Human Cell, 2022)

Paracoccus shandongensis sp. nov., Isolated from Activated Sludge - Xiao-Fan Gong; Fang Wang; Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Zong-Jun Du; Qiang Li (Current Microbiology, 2022)

Fracture analysis of central-flawed rock-like specimens under the influence of coplanar or non-coplanar edge flaws - Zhizhen Liu; Ping Cao; Kaihui Li; Fei Wang; Tao Dong; Jingshuo Liu (Bulletin of Engineering Geology and the Environment, 2022)

Azospirillum tabaci sp. nov., a bacterium isolated from rhizosphere soil of Nicotiana tabacum L - Yan-Qing Duan; Xing-Kui Zhou; Neeli Habib; Shi-Qiang Gao; Li-Min Dong; Xiao-Fei Liu; Yang-Mei Shi; Wen-Jun Li; Gang Du (Archives of Microbiology, 2022)

Mesorhizobium xinjiangense sp. nov., isolated from rhizosphere soil of Alhagi sparsifolia - Dong Meng; Yu-Ling Liu; Jun-Jie Zhang; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Heng Meng; Zong-Jun Du; Wei-Min Li; Qiang Li (Archives of Microbiology, 2022)

Review of the regional nomenclature and tectonic setting for mesozoic gold deposits in the Malanyu Anticline area of Eastern Hebei Province, North China - Leon Bagas; Frank Bierlein; Si-Hong Jiang; Yi-Fei Liu; Li-Li Zhang (International Geology Review, 2021)

A Review of Methods for Ship Detection with Electro-Optical Images in Marine Environments - Liqian Wang; Shuzhen Fan; Yunxia Liu; Yongfu Li; Cheng Fei; Junliang Liu; Bohan Liu; Yakui Dong; Zhaojun Liu; Xian Zhao (Journal of Marine Science and Engineering, 2021)
The ocean connects all continents and is an important space for human activities. Ship detection with electro-optical images has shown great potential due to the abundant imaging spectrum and, hence, strongly supports human activities in the ocean. A suitable imaging spectrum can obtain effective images in complex marine environments, which is the premise of ship detection. This paper provides an overview of ship detection methods with electro-optical images in marine environments. Ship detection methods with sea–sky backgrounds include traditional and deep learning methods. Traditional ship detection methods comprise the following steps: preprocessing, sea–sky line (SSL) detection, region of interest (ROI) extraction, and identification. The use of deep learning is promising in ship detection; however, it requires a large amount of labeled data to build a robust model, and its targeted optimization for ship detection in marine environments is not sufficient.

Application of intelligent speech analysis based on BiLSTM and CNN dual attention model in power dispatching - Zeng Shibo; Hong Danke; Hu Feifei; Liu Li; Xie Fei (Nanotechnology for Environmental Engineering, 2021)

Effects of Water Temperature on Soil Water Infiltration Characteristics Under Film-Mulched Drip Irrigation - Lihua Liu; Liangjun Fei; Hongyan Zhu; Kun Hao; Jingsi Li (Journal of Soil Science and Plant Nutrition, 2021)

Whole Genomic DNA Methylation Profiling of CpG Sites in Promoter Regions of Dorsal Root Ganglion in Diabetic Neuropathic Pain Mice - Wen Chen; Ting Lan; Qingyu Sun; Yurui Zhang; Danmin Shen; Tingting Hu; Jing Liu; Yingzi Chong; Peipei Wang; Qian Li; Weihua Cui; Fei Yang (Journal of Molecular Neuroscience, 2021)

Detoxification difference of cadmium between the application of selenate and selenite in native cadmium-contaminated soil - Mingxing Qi; Yang Liu; Yanan Li; Min Wang; Nana Liu; Pornpimol Kleawsampanjai; Fei Zhou; Hui Zhai; Mengke Wang; Quang Toan Dinh; Rui Ren; Dongli Liang (Environmental Science and Pollution Research, 2021)

Australian propolis ethanol extract exerts antibacterial activity against methicillin-resistant Staphylococcus aureus by mechanisms of disrupting cell structure, reversing resistance, and resisting biofilm - Fei Wang; Hui Liu; Junya Li; Wenwen Zhang; Bin Jiang; Hongzhuan Xuan (Brazilian Journal of Microbiology, 2021)

Alkaloids with acetylcholinesterase inhibitory activity from Corydalis racemosa (Thunb.) Pers - Hui-Na Yao; Zhi-Tian Peng; Yun-Feng Zhang; Di-Fa Liu; Bing-Feng Huang; Peng-Fei Tu; Yun-Fang Zhao; Hui-Xia Huo; Jun Li (Natural Product Research, 2021)

Optimization of 4D flow MRI velocity field in the aorta with divergence-free smoothing - Qi Gao; Xingli Liu; Hongping Wang; Peng Wu; Mansu Jin; RunJie Wei; Wei Wang; Zhaozhuo Niu; Shihua Zhao; Fei Li (Medical & Biological Engineering & Computing, 2021)

Reduced acetylcholine and elevated muscarinic receptor 2 in duodenal mucosa contribute to the impairment of mucus secretion in 6-hydroxydopamine-induced Parkinson’s disease rats - Jing-Ting Yan; Xiao-Yu Liu; Jing-Hua Liu; Guang-Wen Li; Li-Fei Zheng; Xiao-Li Zhang; Yue Zhang; Xiao-Yan Feng; Jin-Xia Zhu (Cell and Tissue Research, 2021)

Vanillic acid combats Vibrio alginolyticus by cell membrane damage and biofilm reduction - Huan Liu; Miao Xiao; Jing Zuo; Xiaoxian He; Ping Lu; Yingyu Li; Yanni Zhao; Fei Xia (Journal of Fish Diseases, 2021)
Antibiotics are the most powerful weapon against bacterial infectious diseases in aquaculture. However, the indiscriminate usage of antibiotics often culminates in the emerging development of antibiotic‐resistant bacteria, making it imperative to search for novel types of antimicrobial agents. This study investigated the antibacterial and antivirulence effects of vanillic acid (VA) against the fish pathogen, Vibrio alginolyticus . We showed that VA had a good anti‐ Vibrio activity with minimal inhibitory concentration (MIC) of 1.0 mg/ml. In addition, VA wielded its antibacterial action in a dose‐/time‐dependent manner by causing cell membrane damage and increasing membrane permeability, which is evidenced by increasing the conductivity and malondialdehyde content in the treated cell cultures and the scanning electron microscopy images. Furthermore, VA significantly reduced the biofilm‐forming capability, mobility and exotoxin production (protease and exopolysaccharide) and downregulation of the expression of biofilm‐ and virulence‐associated genes ( sypG , fliS , fliK , lafA , lafK , asp and luxR ) was seen in the V. alginolyticus that exposed to VA at subinhibitory concentrations. Overall, our findings suggested that VA may be of interest for treating V. alginolyticus ‐associated infections in aquaculture.

Phosphorus rather than nitrogen regulates ecosystem carbon dynamics after permafrost thaw - Guibiao Yang; Yunfeng Peng; Benjamin W. Abbott; Christina Biasi; Bin Wei; Dianye Zhang; Jun Wang; Jianchun Yu; Fei Li; Guanqin Wang; Dan Kou; Futing Liu; et al. (Global Change Biology, 2021)
Ecosystem carbon (C) dynamics after permafrost thaw depends on more than just climate change since soil nutrient status may also impact ecosystem C balance. It has been advocated that nitrogen (N) release upon permafrost thaw could promote plant growth and thus offset soil C loss. However, compared with the widely accepted C‐N interactions, little is known about the potential role of soil phosphorus (P) availability. We combined 3‐year field observations along a thaw sequence (constituted by four thaw stages, i.e., non‐collapse and 5, 14, and 22 years since collapse) with an in‐situ fertilization experiment (included N and P additions at the level of 10 g N m −2 year −1 and 10 g P m −2 year −1 ) to evaluate ecosystem C‐nutrient interactions upon permafrost thaw. We found that changes in soil P availability rather than N availability played an important role in regulating gross primary productivity and net ecosystem productivity along the thaw sequence. The fertilization experiment confirmed that P addition had stronger effects on plant growth than N addition in this permafrost ecosystem. These two lines of evidence highlight the crucial role of soil P availability in altering the trajectory of permafrost C cycle under climate warming.

Cytochalasins from endophytic Diaporthe sp. GDG-118 - Xishan Huang; Dexiong Zhou; Yan Liang; Xiaobo Liu; Fei Cao; Yuyue Qin; Tuxiang Mo; Zhaolong Xu; Jun Li; Ruiyun Yang (Natural Product Research, 2021)

Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice - Lin Chen; Shu-Yu Ren; Rui-Xue Li; Kun Liu; Jing-Fei Chen; Yu-Jian Yang; Yong-Bin Deng; Han-Zhi Wang; Lan Xiao; Feng Mei; Fei Wang (Neuroscience Bulletin, 2021)
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths ( NG2-CreER TM ; Tau-mGFP ), we found that myelinogenesis was highly active in most brain regions, such as the motor cortex and corpus callosum. After exposure to hypoxia (10% oxygen) 12 h per day for 4 weeks, myelinogenesis was largely inhibited in the 4-month old brain and the mice displayed motor coordination deficits revealed by the beam-walking test. To determine the relationship between the inhibited myelination and functional impairment, we induced oligodendroglia-specific deletion of the transcription factor Olig2 by tamoxifen ( NG2-CreER TM ; Tau-mGFP; Olig2 fl/fl ) in adult mice to mimic the decreased myelinogenesis caused by hypoxia. The deletion of Olig2 inhibited myelinogenesis and consequently impaired motor coordination, suggesting that myelinogenesis is required for motor function in adult mice. To understand whether enhancing myelination could protect brain functions against hypoxia, we treated hypoxic mice with the myelination-enhancing drug-clemastine, which resulted in enhanced myelogenesis and improved motor coordination. Taken together, our data indicate that chronic hypoxia inhibits myelinogenesis and causes functional deficits in the brain and that enhancing myelinogenesis protects brain functions against hypoxia-related deficits.

Study on synthesis and anticancer activity of 17beta-estradiol-phenol/aniline nitrogen mustard derivatives - Yu-dong Yin; Jing-jing Liu; Wen-fei Liao; Xian-kun Guo; Li-shan Zhang; Wei-bin Mo; Ke-guang Cheng (Medicinal Chemistry Research, 2021)

First report of Pseudomonas oryzihabitans causing fruit black rot in prickly ash in China - Zhongxuan Liu; Yaowei He; Zhun Xiang; Yihua Yang; Fei Nie; Xuefeng Liu; Zhengyin Li; Qingxian Zeng (Journal of Plant Diseases and Protection, 2021)

Humoral immune durability of IgG for anti-SARS-CoV-2 in the normal pregnant women in Wuhan, China - Hongwen Ma; Jing Peng; Ruobing Li; Xuan Zheng; Shiyao Wu; Heng Yin; Min Li; Liu Qin; Fei Tang; Yun Zhao (Immunologic Research, 2021)

Higher photocatalytic removal of organic pollutants using pangolin-like composites made of 3–4 atomic layers of MoS2 nanosheets deposited on tourmaline - Ming Hao; Hao Li; Li Cui; Wei Liu; Baizeng Fang; Jinsheng Liang; Xinlei Xie; Dongxu Wang; Fei Wang (Environmental Chemistry Letters, 2021)

Controls on the Northward Movement of the ITCZ over the South China Sea in Autumn: A Heavy Rain Case Study - Fei Wang; Lifang Sheng; Xiadong An; Qian Liu; Haixia Zhou; Yingying Zhang; Jianping Li (Advances in Atmospheric Sciences, 2021)

Influence of elevation on bioregionalisation: A case study of the Sino‐Himalayan flora - Yun Liu; Jian‐Fei Ye; Hai‐Hua Hu; Dan‐Xiao Peng; Li‐Na Zhao; Li‐Min Lu; Wajid Zaman; Zhi‐Duan Chen (Journal of Biogeography, 2021)
Aim Elevation is an important factor that influences bioregionalisation in mountainous areas, but its effects are not well known. Taking the Sino‐Himalayan flora as a case, we aimed to test the effect of elevation on bioregionalisation and provide a regionalisation scheme of the Sino‐Himalayan flora. Location The Sino‐Himalaya (East Himalaya, the Hengduan Mountains and the Yunnan Plateau in China). Taxon Angiosperms. Methods We compiled distribution data and elevation ranges of angiosperms in the Sino‐Himalaya and adjacent areas and reconstructed a species‐level phylogenetic tree of 19,313 angiosperm species. The area was divided into 398 grid cells, each 1 × 1°. Nine datasets of different elevation ranges were then used to delineate the flora of the Sino‐Himalaya and adjacent areas using the phylogenetic dissimilarity approach. Results A comparison of nine regionalisation schemes of the Sino‐Himalayan flora based on different elevation range datasets revealed that more than half of grid cells were allocated to more than one subregion. Most of these grid cells were located in areas with a wide range of elevation and/or at the boundaries between subregions. After revising the subregion allocations of eight shifting grid cells, we generated a phylogeny‐ and elevation‐based regionalisation scheme of three regions, comprising eight subregions, for the Sino‐Himalayan flora. Main conclusions By integrating phylogenetic and elevational information, the Sino‐Himalaya can be divided into three floristic regions: the Yunnan Plateau region, the Hengduan Mountains region and the East Himalaya region. Our study provides novel insights into the regionalisation of the flora and highlights the importance of incorporating elevation data in the bioregionalisation of areas with a broad elevational range.

Effects of α-linolenic acid intake on blood lipid profiles：a systematic review and meta-analysis of randomized controlled trials - Hao Yue; Bin Qiu; Min Jia; Wei Liu; Xiao-fei Guo; Na Li; Zhi-xiang Xu; Fang-ling Du; Tongcheng Xu; Duo Li (Critical Reviews in Food Science and Nutrition, 2021)

Spatial and temporal characteristics of harmful algal blooms in Zhejiang Province waters during 1933–2018 - Wen Shiyong; Sun Tianli; Wang Zizhu; Li Fei; Li Dongmei; Liu Na (Marine Biology Research, 2021)

Problem-solving deficits in methcathinone use disorder - Hang-Bin Zhang; Di Zhao; Yu-Ping Liu; Li-Xun Wang; Bo Yang; Ti-Fei Yuan (Psychopharmacology, 2021)

Influencing factors and physiochemical changes of embryogenesis through in vitro isolated microspore culture in Brassica species - Yan-Qi Dong; Yu-Hong Gao; Te Zhao; Guang-Qian Ren; Yan-Li Liu; Bin Guan; Rong-Xian Jin; Fei Gao; Yan-Li Zhang; Xiu-Fang Tan; Hong-Cai Zhu; Yu-Hong Zhang; et al. (Biologia, 2021)

Corticosterone Can Be an Essential Stress Index in Channel Catfish (Ictalurus punctatus) - Kang Xiao; Xi Wang; Wen-Bin Liu; Ding-Dong Zhang; Xiang-Fei Li; Chun-Nuan Zhang; Wei-Hua Chen; Kenneth Prudence Abasubong; Guang-Zhen Jiang (Frontiers in Marine Science, 2021)
Although cortisol is considered the main glucocorticoid involved in regulating stress in fish by elevating the serum glucose, the presence of serum corticosterone and whether its level can be used as an indicator for fish stress activation and reflect the degree of fish stress remains to be determined. To comprehensively and accurately evaluate the performance of two glucocorticoids after stress, in this study, seven of the most common stressors (ammonia nitrogen, high-temperature, acid, alkali, Aeromonas hydrophila, and salinity) in aquaculture were selected. The levels of serum corticosterone, cortisol, and glucose were detected within 48 h, and then the dynamic changes were analyzed. In addition, the kidneys were collected to detect the expression of corresponding proteins involved in corticosterone and cortisol synthesis (3 β-HSD and CYP17A1) for further exploration. From the results obtained, the content of serum corticosterone was about 100 times higher than that of cortisol, and it was found that corticosterone and cortisol showed different dynamic changes within 48 h among the seven kinds of stress. In the subsequent detection of glucose, it was found that the dynamic shift in glucose was not consistent with the dynamic changes of corticosterone or cortisol entirely but seemed to be caused by the combination of the two. In the follow-up protein expression detection, we found that corticosterone seemed to respond to stress earlier. Therefore, it is concluded that the responses of corticosterone and cortisol to stress are independent, corticosterone may be more sensitive in the current seven acute stresses, and then they regulate glucose together to resist stress. The study aimed to fill the vacancy of corticosterone in fish research and provide a reference for the complete evaluation of fish stress degree.

Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination - Kun Liu; Bin Yu; Jing-Fei Chen; Rui-Xue Li; Lin Chen; Shu-Yu Ren; Fei Wang; Feng Mei; Lan Xiao (Neuroscience Bulletin, 2021)
Increasing evidence has shown that astrocytes are implicated in regulating oligodendrocyte myelination, but the underlying mechanisms remain largely unknown. To understand whether microRNAs in astrocytes function in regulating oligodendroglial differentiation and myelination in the developing and adult CNS, we generated inducible astrocyte-specific Dicer conditional knockout mice (hGFAP-CreERT; Dicer fl/fl). By using a reporter mouse line (mT/mG), we confirmed that hGFAP-CreERT drives an efficient and astrocyte-specific recombination in the developing CNS, upon tamoxifen treatment from postnatal day 3 (P3) to P7. The Dicer deletion in astrocytes resulted in inhibited oligodendroglial differentiation and myelination in the developing CNS of Dicer cKO mice at P10 and P14, and did not alter the densities of neurons or axons, indicating that Dicer in astrocytes is required for oligodendrocyte myelination. Consequently, the Dicer deletion in astrocytes at P3 resulted in impaired spatial memory and motor coordination at the age of 9 weeks. To understand whether Dicer in astrocytes is also required for remyelination, we induced Dicer deletion in 3-month-old mice and then injected lysolecithin into the corpus callosum to induce demyelination. The Dicer deletion in astrocytes blocked remyelination in the corpus callosum 14 days after induced demyelination. Together, our results indicate that Dicer in astrocytes is required for oligodendroglia myelination in both the developing and adult CNS.

Safety evaluation and ibuprofen removal via an Alternanthera philoxeroides-based biochar - Yuan-da Du; Xin-qian Zhang; Li Shu; Yu Feng; Cui Lv; Hong-qiang Liu; Fei Xu; Qian Wang; Cong-cong Zhao; Qiang Kong (Environmental Science and Pollution Research, 2021)

Paracoccus binzhouensis sp. nov., isolated from activated sludge - Fang Wang; Xiao-Fan Gong; Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Zong-Jun Du; Qiang Li (Archives of Microbiology, 2021)

Reproductive characteristics of Psilorhynchus homaloptera Hora and Mukerji, 1935 (Cyprinidae: Psilorhynchidae) in the lower Yarlung Zangbo River, Tibet - Pengcheng Lin; Huaming Hu; Fei Liu; Mingzheng Li; Huanzhang Liu (Journal of Oceanology and Limnology, 2021)

MFGE8 mitigates brain injury in a rat model of SAH by maintaining vascular endothelial integrity via TIGβ5/PI3K/CXCL12 signaling - Jikai Wang; Yiping Wang; Yuchun Zuo; Jiajia Duan; Aihua Pan; Jian-Ming Li; Xiao-Xin Yan; Fei Liu (Experimental Brain Research, 2021)

Unsaturated creep behaviors and creep model of slip-surface soil of a landslide in Three Gorges Reservoir area, China - Shimei Wang; Qinghua Zhan; Li Wang; Fei Guo; Ting Liu; Yuchen Pan (Bulletin of Engineering Geology and the Environment, 2021)

Heavy Metals in Indoor Dust Across China: Occurrence, Sources and Health Risk Assessment - Baolin Liu; Fei Huang; Yong Yu; Xuedong Li; Yaowei He; Lei Gao; Xin Hu (Archives of Environmental Contamination and Toxicology, 2021)

Spatio-temporal evolution and future scenario prediction of karst rocky desertification based on CA–Markov model - Fei Chen; Shijie Wang; Xiaoyong Bai; Fang Liu; Yichao Tian; Guangjie Luo; Qin Li; Jingfeng Wang; Luhua Wu; Yue Cao; Huiwen Li; Yuanhong Deng; et al. (Arabian Journal of Geosciences, 2021)

Administration of a recombinant ALDH7A1 (rA7) indicates potential regulation of the metabolite and immunology pathways in Atlantic salmon infected with Aeromonas salmonicida - Xiaohao Li; Kunpeng Fan; Yafang Liu; Ying Liu; Peng‐fei Liu (Journal of Fish Diseases, 2021)
The bacterium Aeromonas salmonicida is the pathogen responsible for furunculosis, which is a serious disease of salmonids. This disease has a significant economic impact on the economic benefits of the global salmon farming industry. However, the pathogenesis of this disease in fish is still unknown. Members of the aldehyde dehydrogenase gene (ALDH) superfamily play a key role in the enzyme detoxification of endogenous and exogenous aldehydes. In this study, we obtained a recombinant aldehyde dehydrogenase 7A1 (ALDH7A1) protein to find its functions on Atlantic salmon infected by A. salmonicida . The transcriptional response in the liver of Atlantic salmon ( Salmo salar ) with differing levels of A. salmonicida infection was analysed and compared in order to reveal mechanisms by which ALDH7A1 may confer infection resistance. With the addition of ALDH7A1 protein, it was found that a total of 13,369 genes were annotated with one or more KEGG and localized to 360 KEGG pathways in the high concentration infection group. The differential expression genes were more enriched in immune signalling pathways such as the Toll‐like receptor signalling pathway, NF‐kappa B signalling pathway and TNF signalling pathway. On the other hand, at low concentrations of infection, KEGG enriched a smaller number of differential expression genes. However, these differential genes were more concentrated in immune signalling pathways such as the PI3K‐Akt signalling pathway, JAK‐STAT signalling pathway and complement and coagulation cascades. In addition, several known immune‐related genes including HSP90α , HSP70 , DNA damage‐inducible transcript 4 , integrin alpha 5 and microtubule‐associated protein 2 were among the differentially expressed transcripts. These data provide the first insights into the host–ALDH7A1 vaccine interactome. The results of this study contribute to identifying the potential resistance mechanisms of Atlantic salmon to A. salmonicida infection and determining future treatment strategies.

Different posterior hippocampus and default mode network modulation in young APOE ε4 carriers: a functional connectome-informed phenotype longitudinal study - Li Juan Zheng; Li Lin; U. Joseph Schoepf; Akos Varga-Szemes; Rock H. Savage; Han Zhang; Yun Fei Wang; Xin Yuan Zhang; Song Luo; Ya Liu; Gui Fen Yang; Guang Ming Lu; et al. (Molecular Neurobiology, 2021)

Al-PHOSLOCK thin-layer capping to control phosphorus release from sediment: effect of hydraulic retention time and phosphorus migration/transformation mechanism - Canyang Lin; Shuwen Li; Bolin Zhu; Shupo Liu; Fei Li; Zhenming Zhou; Tao Li (Journal of Soils and Sediments, 2021)

The effect of organic solvent washing on the structure of hydrochar-based dissolved organic matters and its potential environmental toxicity - Guangping Fan; Fei Tong; Weiguo Zhang; Gaoling Shi; Wei Chen; Lizhu Liu; Jiangye Li; Zhenhua Zhang; Yan Gao (Environmental Science and Pollution Research, 2021)

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020 - Encheng Sun; Zhenjiang Zhang; Zilong Wang; Xijun He; Xianfeng Zhang; Lulu Wang; Wenqing Wang; Lianyu Huang; Fei Xi; Haoyue Huangfu; Ghebremedhin Tsegay; Hong Huo; et al. (Science China Life Sciences, 2021)

Neuromodulation-Based Stem Cell Therapy in Brain Repair: Recent Advances and Future Perspectives - Ti-Fei Yuan; Yi Dong; Li Zhang; Jieyu Qi; Chun Yao; Yongjun Wang; Renjie Chai; Yan Liu; Kwok-Fai So (Neuroscience Bulletin, 2021)

Development and evaluation of a serological test for diagnosis of COVID-19 with selected recombinant spike proteins - Pingping Zhang; Qi Gao; Tang Wang; Yuehua Ke; Fei Mo; Ruizhong Jia; Wanbing Liu; Lei Liu; Shangen Zheng; Yuzhen Liu; Luping Li; Yao Wang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Evaluation of the efficacy and safety of hydroxychloroquine in comparison with chloroquine in moderate and severe patients with COVID-19 - Qiuyu Li; Cheng Cui; Fei Xu; Jianping Zhao; Nan Li; Haichao Li; Tianbing Wang; Hua Zhang; Na Liu; Yudong Wei; Xiaoye Niu; Yan Xu; et al. (Science China Life Sciences, 2021)

The effect of secondary capping on the control of phosphorus release from sediment by activated thin-layer capping with Al-PIA - Bolin Zhu; Shuwen Li; Canyang Lin; Shupo Liu; Fei Li; Zhenming Zhou (Environmental Science and Pollution Research, 2021)

Chelativorans alearense sp. nov., A Novel Bacterial Species Isolated From Soil in Alear, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Current Microbiology, 2021)

Sediment Characteristics, Sources, and Transport Patterns in Kompong Som Bay, Cambodia: Indications from Grain Size and Heavy Minerals - Jinqing Liu; Xiaoying Chen; Ping Yin; Ke Cao; Fei Gao; Yuanku Meng; Jiandong Qiu; Meina Li (Journal of Ocean University of China, 2021)

Comprehensive Marine Observing Experiment Based on High-Altitude Large Unmanned Aerial Vehicle (South China Sea Experiment 2020 of the “Petrel Project”) - Xuefen Zhang; Liangxu Li; Rongkang Yang; Ran Guo; Xia Sun; Jianping Luo; Hongbin Chen; Daxin Liu; Kebing Tang; Wenwu Peng; Xiaodong Han; Qiyun Guo; et al. (Advances in Atmospheric Sciences, 2021)

New cytotoxic biflavones from Selaginella doederleinii - Li-Fei Liu; Hui-Hui Sun; Jian-Bing Tan; Qi Huang; Fei Cheng; Kang-Ping Xu; Zhen-Xing Zou; Gui-Shan Tan (Natural Product Research, 2021)

New biphenanthrenes with butyrylcholinesterase inhibitory activitiy from Cremastra appendiculata - Liang Liu; Qi-Meng Yin; Qian Gao; Jun Li; Yong Jiang; Peng-Fei Tu (Natural Product Research, 2021)

Snapshot of the Pliocene environment of West Kunlun region, Northwest China - Jia Liu; Teng-Xiang Wang; Xin-Wen Zhang; Ai Song; Shu-Feng Li; Jian Huang; Teresa Spicer; Robert A. Spicer; Fei-Xiang Wu; Tao Su; Zhe-Kun Zhou (Palaeobiodiversity and Palaeoenvironments, 2021)

Thiazole-based and thiazolidine-based protein tyrosine phosphatase 1B inhibitors as potential anti-diabetes agents - Kexin Chen; Xu Yao; Ting Tang; Li-Mei Chen; Can Xiao; Jing-Yi Wang; Hong-Fei Chen; Zhong-Xing Jiang; Yi Liu; Xing Zheng (Medicinal Chemistry Research, 2021)

Chronic stress promotes acute myeloid leukemia progression through HMGB1/NLRP3/IL-1β signaling pathway - Na Liu; Yifan Wu; Xin Wen; Peng Li; Fei Lu; Hong Shang (Journal of Molecular Medicine, 2021)

Source Apportionment and Ecological-Health Risks Assessment of Heavy Metals in Topsoil Near a Factory, Central China - Jia Li; Guangcai Wang; Fei Liu; Linfeng Cui; Yanjun Jiao (Exposure and Health, 2021)

Chelativorans xinjiangense sp. nov., a novel bacterial species isolated from soil in Xinjiang, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Archives of Microbiology, 2021)

Propylenella binzhouense gen. nov., sp. nov. isolated from activated sludge, and proposal of Propylenellaceae fam. nov. - Yu-Ling Liu; Dong Meng; Fang Wang; Xiao-Fan Gong; Peng-Fei Gu; Xiang-Yu Fan; Zong-Jun Du; Ji-Dong Zou; Qiang Li (Antonie van Leeuwenhoek, 2021)

Antagonism of Protease-Activated Receptor 4 Protects Against Traumatic Brain Injury by Suppressing Neuroinflammation via Inhibition of Tab2/NF-κB Signaling - Jianing Luo; Xun Wu; Haixiao Liu; Wenxing Cui; Wei Guo; Kang Guo; Hao Guo; Kai Tao; Fei Li; Yingwu Shi; Dayun Feng; Hao Yan; et al. (Neuroscience Bulletin, 2021)

TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial–mesenchymal transition - Zhi-Han Li; Lei Lei; Liang-Ru Fei; Wen-Jing Huang; Yi-Wen Zheng; Mai-Qing Yang; Zhao Wang; Chen-Chen Liu; Hong-Tao Xu (Journal of Molecular Histology, 2021)

IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis - Yanan Xu; Xiaoyu Huang; Fengzhan Li; Tan Liu; Tingting Yang; Fei Chen; Jie Zhu; Meng Pan; Yong Zhang; Yuzhong Wang; Linlin Fu; Chenghua Xiao; et al. (Immunologic Research, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

NUIST ESM v3 Data Submission to CMIP6 - Jian Cao; Libin Ma; Fei Liu; Jing Chai; Haikun Zhao; Qiong He; Bo Wang; Yan Bao; Juan Li; Young-min Yang; Hua Deng; Bin Wang (Advances in Atmospheric Sciences, 2021)
This paper introduces the experimental designs and outputs of the Diagnostic, Evaluation and Characterization of Klima (DECK), historical, Scenario Model Intercomparison Project (MIP), and Paleoclimate MIP (PMIP) experiments from the Nanjing University of Information Science and Technology Earth System Model version 3 (NESM3). Results show that NESM3 reasonably simulates the modern climate and the major internal modes of climate variability. In the Scenario MIP experiment, changes in the projected surface air temperature (SAT) show robust “Northern Hemisphere (NH) warmer than Southern Hemisphere (SH)” and “land warmer than ocean” patterns, as well as an El Niño-like warming over the tropical Pacific. Changes in the projected precipitation exhibit “NH wetter than SH” and “eastern hemisphere gets wetter and western hemisphere gets drier” patterns over the tropics. These precipitation patterns are driven by circulation changes owing to the inhomogeneous warming patterns. Two PMIP experiments show enlarged seasonal cycles of SAT and precipitation over the NH due to the seasonal redistribution of solar radiation. Changes in the climatological mean SAT, precipitation, and ENSO amplitudes are consistent with the results from PMIP4 models. The NESM3 outputs are available on the Earth System Grid Federation nodes for data users.

A moso bamboo transcription factor, Phehdz1, positively regulates the drought stress response of transgenic rice - Yameng Gao; Huanlong Liu; Kaimei Zhang; Fei Li; Min Wu; Yan Xiang (Plant Cell Reports, 2021)

Resazurin as an indicator of reducing capacity for analyzing the physiologic status of deep-sea bacterium Photobacterium phosphoreum ANT-2200 - Jie Dai; Hongzhi Tang; Xuegong Li; Claire-Lise Santini; Wenpeng Cui; Na Liu; Xiaoqing Qi; Xuehua Cui; Alain Grossi; Philippe Notareschi; Wei-Jia Zhang; Long-Fei Wu (Journal of Oceanology and Limnology, 2021)

On the connection between AMOC and observed land precipitation in Northern Hemisphere: a comparison of the AMOC indicators - Jing Zhang; Yusen Liu; Cheng Sun; Jianping Li; Ruiqiang Ding; Fei Xie; Tiejun Xie; Yazhou Zhang; Zhanqiu Gong (Climate Dynamics, 2021)

Characterizing spatiotemporal rainfall changes in 1960–2019 for continental Australia - De Li Liu; Jin Teng; Fei Ji; Muhuddin R. Anwar; Puyu Feng; Bin Wang; Linchao Li; Cathy Waters (International Journal of Climatology, 2021)
Understanding changes in rainfall at a continental scale can inform adaptation and resilience in all sectors that are sensitive to rainfall. This study examined spatiotemporal changes in annual and seasonal rainfall, extreme and non‐extreme rainfall, and their probability and intensity over the period from 1960 to 2019 across Australia for six rainfall zones (RZs) using high‐quality daily rainfall from 7,593 climate stations. The results revealed statistically significant changes in long‐term rainfall, with an increasing trend in Northern and Central Australia, and a decreasing trend across Southern Australia where the main agricultural areas are located. The cross‐wavelet power spectrum analysis denoted strong coherent resonance cycles in spring–summer or autumn–winter seasons with varying phase differences across six RZs. More specifically, summer rainfall occurred more regularly in the summer‐dominant and arid RZs, whereas winter rainfall became more unreliable in the winter‐ and winter‐dominant RZs. The changes in regional rainfall were characterized by changes in probability and/or intensity of extreme and non‐extreme rainfall revealed through the Spearman Rank correlation. The upward trend in summer‐dominant and arid RZs appears to be a result of increased extreme rainfall intensity and probability, and non‐extreme rainfall probability, especially in summer. The decreased rainfall in the rest of the RZs can be attributed to decreased extreme rainfall probability and non‐extreme rainfall intensity. These results can help decision makers in the agricultural and water resources management sectors identify risks and opportunities, and to devise strategic plans to mitigate droughts through land use planning and construction of infrastructure.

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Production of functional human nerve growth factor from the submandibular glands of mice using a CRISPR/Cas9 genome editing system - Yi Gu; Hui Cao; Fei Li; Jianli Yu; Rui Nian; Dongxiao Feng; Jingtao Lin; Haipeng Song; Wenshuai Liu (World Journal of Microbiology and Biotechnology, 2020)

Experimental Study on Coal Damage Subjected to Microwave Heating - He Li; Li Tian; Bingxiang Huang; Jiexin Lu; Shiliang Shi; Yi Lu; Fei Huang; Yong Liu; Xiangnan Zhu (Rock Mechanics and Rock Engineering, 2020)

Optimizing Human Epidermal Growth Factor for its Endurance and Specificity Via Directed Evolution: Functional Importance of Leucine at Position 8 - Yujie Sun; Nanyan Yang; Fei Li; Jinxin Ou; Xin Liu; Qing Zhang (International Journal of Peptide Research and Therapeutics, 2020)

Immune characteristics distinguish patients with severe disease associated with SARS-CoV-2 - Xiaolei Li; Yang Liu; Junming Li; Longhua Sun; Jibin Yang; Fei Xu; Jing Zhou; Lagen Wan; Xinping Xu; Aiping Le; Wei Zhang (Immunologic Research, 2020)

Correction to: The effect of teprenone on the intestinal morphology and microbial community of Chinese sea bass (Lateolabrax maculatus) under intermittent hypoxic stress - Hong-biao Dong; Yong-xu Sun; Ya-fei Duan; Hua Li; Yong Li; Qing-song Liu; Wen-hao Wang; Jia-song Zhang (Fish Physiology and Biochemistry, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Pseudorabies virus production using a serum-free medium in fixed-bed bioreactors with low cell inoculum density - Jianqi Nie; Yang Sun; Feng Peng; Fei Han; Yankun Yang; Xiuxia Liu; Chunli Liu; Ye Li; Zhonghu Bai (Biotechnology Letters, 2020)

Gut dysbiosis-influence on amygdala-based functional activity in patients with end stage renal disease: a preliminary study - Li Juan Zheng; Li Lin; Jianhui Zhong; Zhihong Zhang; Yu Bing Ye; Xin Yuan Zhang; Yun Fei Wang; Han Zhang; Ya Liu; Guang Ming Lu; Dehua Gong; Long Jiang Zhang (Brain Imaging and Behavior, 2020)

miR-217/Mafb Axis Involve in High Glucose-Induced β-TC-tet Cell Damage Via Regulating NF-κB Signaling Pathway - Huizhen Zheng; Xinying Li; Xinyu Yang; Fei Yan; Chuan Wang; Jinbo Liu (Biochemical Genetics, 2020)

Prediction and Identification of Epitopes in the Emy162 Antigen of Echinococcus multilocularis - Ming-Quan Pang; Feng Tang; Hai-Jiu Wang; Ying Zhou; Li Ren; Run-Le Li; Hu Zhou; Chen-Fei Wan; Chuan-Chuan Liu; Cai-Rang Yangdan; Hai-Ning Fan (Acta Parasitologica, 2020)

Molecular characterization and pathogenicity analysis of prunus necrotic ringspot virus isolates from China rose (Rosa chinensis Jacq.) - Fei Xing; Dehang Gao; Huan Liu; Hongqing Wang; Nuredin Habili; Shifang Li (Archives of Virology, 2020)

Erratum to: Could the Recent Taal Volcano Eruption Trigger an El Niño and Lead to Eurasian Warming? - Fei Liu; Chen Xing; Jinbao Li; Bin Wang; Jing Chai; Chaochao Gao; Gang Huang; Jian Liu; Deliang Chen (Advances in Atmospheric Sciences, 2020)

Two new anthraquinone derivatives and one new triarylbenzophenone analog from Selaginella tamariscina - Rui Liu; Hui Zou; Zhen-Xing Zou; Fei Cheng; Xia Yu; Ping-Sheng Xu; Xiao-Min Li; Dai Li; Kang-Ping Xu; Gui-Shan Tan (Natural Product Research, 2020)

A combination of linkage mapping and GWAS brings new elements on the genetic basis of yield-related traits in maize across multiple environments - Xiaoxiang Zhang; Zhongrong Guan; Zhaoling Li; Peng Liu; Langlang Ma; Yinchao Zhang; Lang Pan; Shijiang He; Yanling Zhang; Peng Li; Fei Ge; Chaoying Zou; et al. (Theoretical and Applied Genetics, 2020)

Patterns of presence-absence variants in Upland cotton - Junfang Liu; Xianliang Zhang; Lingling Dou; Wei Li; Xiaojian Zhou; Yangai Liu; Xiaoyu Pei; Zhongying Ren; Wensheng Zhang; Huaizhu Li; Wenbo Wang; Changsong Zou; et al. (Science China Life Sciences, 2020)

Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice - Qi Yang; Li Luo; Ting Sun; Le Yang; Li-Fei Cheng; Yan Wang; Qing-Qing Liu; An Liu; Hai-Yan Liu; Ming-Gao Zhao; Sheng-Xi Wu; Bin Feng (Psychopharmacology, 2020)

Verticillin A inhibits colon cancer cell migration and invasion by targeting c-Met - Qian-qian Liu; Xue-li Zeng; Yue-lin Guan; Jing-xin Lu; Kai Tu; Fei-yan Liu (Journal of Zhejiang University-SCIENCE B, 2020)

Reclamation with organic amendments and plants remodels the diversity and structure of bacterial community in ion-adsorption rare earth element mine tailings - Ye Liu; Xi Zhong; Hermine Huot; Wenshen Liu; Chang Liu; Meina Guo; Yaying Li; Yingheng Fei; Yuanqing Chao; Shizhong Wang; Yetao Tang; Rongliang Qiu (Journal of Soils and Sediments, 2020)

The effect of teprenone on the intestinal morphology and microbial community of Chinese sea bass (Lateolabrax maculatus) under intermittent hypoxic stress - Hong-biao Dong; Yong-xu Sun; Ya-fei Duan; Hua Li; Yong Li; Qing-song Liu; Wen-hao Wang; Jia-song Zhang (Fish Physiology and Biochemistry, 2020)

Short-term effects of meteorological factors, air pollution, and sunspot on childhood hand, foot, and mouth disease in Tianjin, China: a new time series regression, 2014–2018 - Xue-Yue Ji; Li-Yuan Huang; Jia Song; Chun-Nan Fei; Jun Liu; He Liu (Environmental Science and Pollution Research, 2020)

A robust relationship between multidecadal global warming rate variations and the Atlantic Multidecadal Variability - Zhiyu Li; Wenjun Zhang; Fei-Fei Jin; Malte F. Stuecker; Cheng Sun; Aaron F. Z. Levine; Haiming Xu; Chao Liu (Climate Dynamics, 2020)

Typical gene expression profile of pseudorabies virus reactivation from latency in swine trigeminal ganglion - Hai-Hua Wang; Jie Liu; Lin-Tao Li; Huan-Chun Chen; Wan-Po Zhang; Zheng-Fei Liu (Journal of NeuroVirology, 2020)

Noise does not equal bias in assessing the evolutionary history of the angiosperm flora of China: A response to Qian (2019) - Li‐Min Lu; Hai‐Hua Hu; Dan‐Xiao Peng; Bing Liu; Jian‐Fei Ye; Tuo Yang; Hong‐Lei Li; Miao Sun; Stephen A. Smith; Pamela S. Soltis; Douglas E. Soltis; Zhi‐Duan Chen (Journal of Biogeography, 2020)
In response to our paper on the evolutionary history of the Chinese flora, Qian suggests that certain features of the divergence time estimation employed might have led to biased conclusions in Lu et al (2018). Here, we consider Qian's specific criticisms, explore the extent of uncertainty in the data and demonstrate that (i) no systematic bias toward dates that are too young or too old is detected in Lu et al.; (ii) constraint of the crown age of angiosperms does not bias the generic ages estimated by Lu et al.; and (iii) ages derived from the Chinese regional phylogeny do not bias the conclusions reported by Lu et al. All these analyses confirm that the conclusions reported previously are robust. We argue that, like many large‐scale biodiversity analyses, sources of noise in divergence time estimation are to be expected, but these should not be confused with bias.

The abscisic acid receptor gene VvPYL4 positively regulates grapevine resistance to Plasmopara viticola - Li Liu; Chang-Yuan Liu; Hui Wang; Shu-Yi Yu; Tian-Shu Guan; Yu-Fei Huang; Rui-Chun Li (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Microinjection of valproic acid into the ventrolateral orbital cortex exerts an antinociceptive effect in a rat of neuropathic pain - Zheng Chu; Peng Liu; Xin Li; Yonglong Liu; Fei Liu; Gang Lei; Liu Yang; Lisha Deng; Yonghui Dang (Psychopharmacology, 2020)

Neonatal Exposure to Anesthesia Leads to Cognitive Deficits in Old Age: Prevention with Intranasal Administration of Insulin in Mice - Chun-Ling Dai; Hengchang Li; Xin Hu; Jin Zhang; Fei Liu; Khalid Iqbal; Cheng-Xin Gong (Neurotoxicity Research, 2020)

Candidate resistance genes selection and transcriptome analysis for the early responses to Plasmopara viticola infection in grape cultivars - Li Liu; Bo Zhang; Hui Wang; Shu Yi Yu; Tian Shu Guan; Yu Fei Huang; Chang Yuan Liu (Journal of Plant Pathology, 2020)

Effects of hydrogeochemical conditions on the distribution of pesticides in the karst river system - Tian Zhou; Fuyang Huang; Chong Zhang; Zeyan Li; Fei Liu (Environmental Science and Pollution Research, 2020)

Spatio-temporal variation and risk assessment of hydrochemical indices in a large diversion project of the Yellow River, northern China, from 2008 to 2017 - Yuan Li; Fei Wang; Jia Feng; Junping Lv; Qi Liu; Fangru Nan; Xudong Liu; Lan Xu; Shulian Xie (Environmental Science and Pollution Research, 2020)

Reclassification of Brevibacterium frigoritolerans DSM 8801T as Bacillus frigoritolerans comb. nov. Based on Genome Analysis - Guo-Hong Liu; Bo Liu; Jie-Ping Wang; Jian-Mei Che; Peng-Fei Li (Current Microbiology, 2020)

Gastric smooth muscle cells manifest an abnormal phenotype in Parkinson’s disease rats with gastric dysmotility - Xiao-Lin Xiu; Li-Fei Zheng; Xiao-Yu Liu; Yan-Yan Fan; Jin-Xia Zhu (Cell and Tissue Research, 2020)

Correction to: Experimental study on the mechanical properties weakening mechanism of siltstone with different water content - Bingyang Li; Jian Liu; Kang Bian; Fei Ai; Xunjian Hu; Ming Chen; Zhenping Liu (Arabian Journal of Geosciences, 2020)

Two new quinolone alkaloids from the nearly ripe fruits of Tetradium ruticarpum - Yi-Heng Li; Xiao Liu; Min Yin; Fei Liu; Bi Wang; Xu Feng; Qi-Zhi Wang (Natural Product Research, 2020)

Could the Recent Taal Volcano Eruption Trigger an El Niño and Lead to Eurasian Warming? - Fei Liu; Chen Xing; Jinbao Li; Bin Wang; Jing Chai; Chaochao Gao; Gang Huang; Jian Liu; Deliang Chen (Advances in Atmospheric Sciences, 2020)

SNX-2112, an Hsp90 inhibitor, suppresses cervical cancer cells proliferation, migration, and invasion by inhibiting the Akt/mTOR signaling pathway - Liang-Shun Fu; Hong-Hong Qiu; Min Liu; Liu-Bing Hu; Yan Wang; Peng-Chao Zhang; Man-Mei Li; Yi-Fei Wang; Zhong Liu (Medicinal Chemistry Research, 2020)

Long-Term Greenhouse Cucumber Production Alters Soil Bacterial Community Structure - Xing Liu; Yujiao Li; Xiujuan Ren; Bihua Chen; Ying Zhang; Changwei Shen; Fei Wang; Dafu Wu (Journal of Soil Science and Plant Nutrition, 2020)

Microbial and metabolomic analysis of gingival crevicular fluid in general chronic periodontitis patients: lessons for a predictive, preventive, and personalized medical approach - Jun Pei; Fei Li; Youhua Xie; Jing Liu; Tian Yu; Xiping Feng (EPMA Journal, 2020)
Objectives General chronic periodontitis (GCP) is a bacterial inflammatory disease with complex pathology. Despite extensive studies published on the variation in the oral microbiota and metabolic profiles of GCP patients, information is lacking regarding the correlation between host-bacterial interactions and biochemical metabolism. This study aimed to analyze the oral microbiome, the oral metabolome, and the link between them and to identify potential molecules as useful biomarkers for predictive, preventive, and personalized medicine (PPPM) in GCP. Methods In this study, gingival crevicular fluid (GCF) samples were collected from patients with GCP ( n = 30) and healthy controls ( n = 28). The abundance of oral microbiota constituents was obtained by Illumina sequencing, and the relative level of metabolites was measured by gas chromatography-mass spectrometry. Full-mouth probing depth, clinical attachment loss, and bleeding on probing were recorded as indices of periodontal disease. Results The relative abundances of 7 phyla and 82 genera differed significantly between the GCP and healthy groups. Seventeen differential metabolites involved in different metabolism pathways were selected based on variable influence on projection values (VIP > 1) and P values ( P < 0.05). Through Spearman’s correlation analysis, microorganisms, metabolites in GCF, and clinical data together showed a clear trend, and clinical data regarding periodontitis can be reflected in the shift of the oral microbial community and the change in metabolites in GCF. A combination of citramalic acid and N-carbamylglutamate yielded satisfactory accuracy (AUC = 0.876) for the predictive diagnosis of GCP. Conclusions Dysbiosis in the polymicrobial community structure and changes in metabolism could be mechanisms underlying periodontitis. The differential microorganisms and metabolites in GCF between periodontitis patients and healthy individuals are possibly biomarkers, pointing to a potential strategy for the prediction, diagnosis, prognosis, and management of personalized periodontal therapy.

Epidemiological survey and genetic evolution of H3N2 subtype influenza viruses from stray dogs in Shanghai, China - Hai-Xiao Shen; Fei-Fei Ge; Xin Li; Jian Liu; Hou-Bing Ju; De-Quan Yang; Xian-Chao Yang; Jian Wang; Hong-Jin Zhao (Virus Genes, 2020)

Efficient deletion of LoxP-flanked selectable marker genes from the genome of transgenic pigs by an engineered Cre recombinase - Xiaoling Huang; Xian Zou; Zhiqian Xu; Fei Tang; Junsong Shi; Enqin Zheng; Dewu Liu; Stefan Moisyadi; Johann Urschitz; Zhenfang Wu; Zicong Li (Transgenic Research, 2020)

Modulation of the Intraseasonal Variability of Pacific-Japan Pattern by ENSO - Ying Li; Fei Liu; Pang-Chi Hsu (Journal of Meteorological Research, 2020)

Neural network–based prediction methods for height of water-flowing fractured zone caused by underground coal mining - Song Dai; Bo Han; Shiliang Liu; Ningbo Li; Fei Geng; Xizhong Hou (Arabian Journal of Geosciences, 2020)

Background Characteristics of Atmospheric CO2 and the Potential Source Regions in the Pearl River Delta Region of China - Boru Mai; Xuejiao Deng; Fang Zhang; Hao He; Tian Luan; Fei Li; Xia Liu (Advances in Atmospheric Sciences, 2020)

Coupling and Decoupling of High Biomass Phytoplankton Production and Hypoxia in a Highly Dynamic Coastal System: The Changjiang (Yangtze River) Estuary - Feng Zhou; Fei Chai; Daji Huang; Mark Wells; Xiao Ma; Qicheng Meng; Huijie Xue; Jiliang Xuan; Pengbin Wang; Xiaobo Ni; Qiang Zhao; Chenggang Liu; et al. (Frontiers in Marine Science, 2020)

Excess DHA Induces Cell Cycle Arrest by Activating the P53/Cycling Pathway in Blunt Snout Bream (Megalobrama amblycephala) - Cong-cong Wang; Wen-bin Liu; Xiu-fei Cao; Yang-yang Huang; Xi Wang; Kang Xiao; Xiang-fei Li; Ding-dong Zhang; Guang-zhen Jiang (Frontiers in Marine Science, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

Characterization of Pseudomonas syringae pv. actinidiae Biovar 3 strain and cultivar tolerance to kiwifruit bacterial canker in China - Zhen-feng Ye; Peng-fei Wei; Shi-zhou Xue; Pu Liu; Bing Jia; Wei Heng; Li-wu Zhu (Journal of Plant Pathology, 2020)

Effects of Fe-Mn-Ce oxide–modified biochar on As accumulation, morphology, and quality of rice (Oryza sativa L.) - Fei Lian; Xuewei Liu; Minling Gao; Huizhong Li; Weiwen Qiu; Zhengguo Song (Environmental Science and Pollution Research, 2020)

Summertime Oxygen Depletion and Acidification in Bohai Sea, China - Guisheng Song; Liang Zhao; Fei Chai; Fangfang Liu; Mengting Li; Huixiang Xie (Frontiers in Marine Science, 2020)

Influences of glycyrrhetinic acid (GA) dietary supplementation on growth, feed utilization, and expression of lipid metabolism genes in channel catfish (Ictalurus punctatus) fed a high-fat diet - Hesham Eed Desouky; Guang-zhen Jiang; Ding-dong Zhang; Kenneth Prudence Abasubong; Xiangyang Yuan; Xiang-fei Li; Wen-bin Liu (Fish Physiology and Biochemistry, 2020)

Tracing solute sources and carbon dynamics under various hydrological conditions in a karst river in southwestern China - Jing Liu; Bo Chen; Zhu-Yan Xu; Yuan Wei; Zhi-Hua Su; Rui Yang; Yong-Xue Ji; Xiao-Dan Wang; Li-Li Zhang; Ning An; Fei Yang (Environmental Science and Pollution Research, 2020)

Interannual Variability and Scenarios Projection of Sea Ice in Bohai Sea Part I: Variation Characteristics and Interannual Hindcast - Yan Jiao; Fei Huang; Qingrong Liu; Ge Li; Yaru Li; Qingxi Yu; Yiding Zhao (Journal of Ocean University of China, 2020)

The implication of spatial interpolated climate data on biophysical modelling in agricultural systems - De Li Liu; Fei Ji; Bin Wang; Cathy Waters; Puyu Feng; Rebecca Darbyshire (International Journal of Climatology, 2020)
Spatial modelling of agricultural production has been more frequently analysed to assist with regional and long‐term planning. Typically, point‐scale crop models are used to construct these analyses with researchers using various sources of input data, including observed and interpolated gridded climate data. Understanding the implication of data choice on production estimates is crucial to appreciate the consequences of selecting methodological approaches for agricultural model outputs. In this study, we compared site observed climate data and gridded data sets interpolated from site observations that are commonly used the Australian climate data set. We assessed the consequences of the differences in climate variables (biases) to the modelled outputs. Our results showed that the major differences between gridded and observed climate data sets were for rainfall variables. Interpolated gridded data tended to have larger rainfall frequency and smaller rainfall intensity, leading to lower surface runoff and higher soil evaporation that caused less plant water uses and less nitrogen uptake, and ultimately resulted in biases in simulated crop biomass and yield. In addition, the results indicated that agricultural models implemented with gridded data could produce similar overall model outputs as those driven by observed climate data, but can result in more uncertainties in simulated spatial outputs. This is particularly evident in regions with high rainfall. Our results showed that applying agricultural models with observed data and then interpolating these results spatially might be the optimal approach to minimize the biases in production modelling outputs and reduce computing time and storage.

Juxtaposed membranes underpin cellular adhesion and display unilateral cell division of multicellular magnetotactic prokaryotes - Xin‐Xin Qian; Claire‐Lise Santini; Artemis Kosta; Nicolas Menguy; Hugo Le Guenno; Wenyan Zhang; Jinhua Li; Yi‐Ran Chen; Jia Liu; François Alberto; Leon Espinosa; Tian Xiao; et al. (Environmental Microbiology, 2020)
Summary Multicellular magnetotactic prokaryotes (MMPs) exhibit peculiar coordination of swimming along geomagnetic field lines. Approximately 40–80 cells assemble, with a helical geometry or axisymmetry, into spherical or ellipsoidal MMPs respectively. To contribute to a comprehensive understanding of bacterial multicellularity here we took multiple microscopic approaches to study the diversity, assembly, reproduction and motility of ellipsoidal MMPs. Using correlative fluorescence in situ hybridization and scanning electron microscopy analysis, we found an unexpected diversity in populations of ellipsoidal MMPs in the Mediterranean Sea. The high‐pressure freezing/freeze substitution fixation technique allowed us to show, for the first time, that cells adhere via juxtaposed membranes and are held together by a rimming lattice. Fluorescence confocal microscopy and ultrathin section images revealed not only the one‐layer hollow three‐dimensional architecture, but also periphery–core unilateral constriction of constituent cells and unidirectional binary fission of the ellipsoidal MMPs. This finding suggests the evolution toward MMPs multicellularity via the mechanism of incomplete separation of offspring. Remarkably, thousands of flagellar at the periphery surface of cells underpin the coordinated swimming of MMPs in response to mechanical, chemical, magnetic and optical stimuli, including a magnetotactic photokinesis behaviour. Together these results unveil the unique structure and function property of ellipsoidal MMPs.

The Arabidopsis UDP-glycosyltransferase75B1, conjugates abscisic acid and affects plant response to abiotic stresses - Ting-Ting Chen; Fang-Fei Liu; Dong-Wang Xiao; Xiao-Yi Jiang; Pan Li; Shu-Man Zhao; Bing-kai Hou; Yan-jie Li (Plant Molecular Biology, 2020)

Isolation, structure elucidation, tyrosinase inhibitory, and antioxidant evaluation of the constituents from Angelica dahurica roots - Penghua Shu; Junping Li; Yingying Fei; Huiqing Zhu; Mengzhu Yu; Anqi Liu; Haoying Niu; Simin Zou; Xialan Wei; Zhiyu Ju; Zhihong Xu (Journal of Natural Medicines, 2020)

Effect of simulated acid rain on stability of arsenic calcium residue in residue field - Jiangchi Fei; Jingjing Ma; Jinqin Yang; Yanjie Liang; Yong Ke; Liwei Yao; Yuancheng Li; Degang Liu; Xiaobo Min (Environmental Geochemistry and Health, 2020)

Construction of a High-Density Genetic Linkage Map and QTL Mapping for Growth-Related Traits in Takifugu bimaculatus - Yue Shi; Zhixiong Zhou; Bo Liu; Shengnan Kong; Baohua Chen; Huaqiang Bai; Leibin Li; Fei Pu; Peng Xu (Marine Biotechnology, 2020)

Novel mutations in SPEF2 causing different defects between flagella and cilia bridge: the phenotypic link between MMAF and PCD - Chaofeng Tu; Hongchuan Nie; Lanlan Meng; Weili Wang; Haiyu Li; Shimin Yuan; Dehua Cheng; Wenbin He; Gang Liu; Juan Du; Fei Gong; Guangxiu Lu; et al. (Human Genetics, 2020)

Application of metagenomic next-generation sequencing for bronchoalveolar lavage diagnostics in critically ill patients - Ying Li; Bing Sun; Xiao Tang; Ya-lan Liu; Hang-yong He; Xu-yan Li; Rui Wang; Fei Guo; Zhao-hui Tong (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

A Review of Research on Tropical Air-Sea Interaction, ENSO Dynamics, and ENSO Prediction in China - Hong-Li Ren; Fei Zheng; Jing-Jia Luo; Run Wang; Minghong Liu; Wenjun Zhang; Tianjun Zhou; Guangqing Zhou (Journal of Meteorological Research, 2020)

Extreme rainfall, rainfall erosivity, and hillslope erosion in Australian Alpine region and their future changes - Qinggaozi Zhu; Xihua Yang; Fei Ji; De Li Liu; Qiang Yu (International Journal of Climatology, 2020)
The Australian Alpine region is highly vulnerable to extreme climate events such as heavy rainfall and snow falls, these events subsequently impact rainfall erosivity and hillslope erosion in the region. In this study, the relationship between extreme rainfall indices (ERIs) and rainfall erosivity was examined across the Alpine region in New South Wales (NSW) and Australian Capital Territory (ACT) and the surrounding areas including Murray and Murrumbidgee and South East and Tablelands (SET). Rainfall erosivity, hillslope erosion, and their changes were estimated in the future periods using the revised universal soil loss equation and the NSW/ACT Regional Climate Modeling (NARCliM) projections. Results from the study demonstrate a good relationship between ERIs (especially Rx5Day) and rainfall erosivity. The rainfall erosivity and hillslope erosion are projected to increase about 2 and 8% for the near future (2020–2039), further increase to 8 and 18% for the far future (2060–2079) in the Alpine region assuming the groundcover is maintained at the current condition. The change in rainfall erosivity and erosion risk is highly uneven in space and in season with the highest erosion risk in summer with an increase about 33% in the next 50 years. The highest erosion risk area is predicted within SET (maximum rate 19.95 Mg ha −1 year −1 ), but on average, the ACT has the highest erosion rate, which is above 1.36 Mg ha −1 year −1 in all periods. The snowmelt in spring in the Alpine region is estimated to increase the rainfall erosivity by 13% in the baseline period, up to 24% in the near future, but far less (about 1%) in the far future due to predicted temperature rise and less snow available in the Alpine region in the next 50 years.

Role of autumn Arctic Sea ice in the subsequent summer precipitation variability over East Asia - Yang Liu; Yali Zhu; Huijun Wang; Yongqi Gao; Jianqi Sun; Tao Wang; Jiehua Ma; Alla Yurova; Fei Li (International Journal of Climatology, 2020)
This study explored the interannual relationship between autumn Arctic sea ice concentration (SIC) and the subsequent summer precipitation over East Asia (EASP). Since the late‐1990s, the declining SIC in the Kara–Laptev Seas has been significantly correlated with EASP as well as extremely positive anomalies in northern China and intensely negative anomalies in central‐eastern East Asia. However, there was a weak correlation between autumn SIC and EASP before the late‐1990s. Furthermore, the anomalous precipitation pattern in summer and its connection with autumn SIC variability can be explained by the seasonal persistence of continental processes (snow depth and soil moisture) into the spring. In particular, a decreasing SIC was connected with simultaneously positive and negative precipitation anomalies over northeastern China and the Siberian region, respectively, since the late‐1990s and tends to produce corresponding soil moisture anomalies over the Eurasian continent. Declining SIC also favours increased snow depth anomalies in winter over northeastern East Asia. These anomalous signals of surface processes can persist from winter into the subsequent spring, making the connection between the autumn SIC and EASP possible. The Community Earth System Model Large Ensemble simulations further verified these physical processes. More detailed mechanism for this relationship needs to be stressed in further work by numerical simulations. The results have important implications for extending the seasonal prediction validity of EASP. Moreover, before the late‐1990s, SIC‐related circulation anomalies shifted westward and northward as negative precipitation anomalies developed over west Siberia in autumn. As a result, anomalous dry soil conditions in Siberia persisted into the subsequent spring and then led to wetter‐than‐normal conditions through locally negative soil moisture–precipitation feedback before the late‐1990s.

Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression - Fang Yang; Wang-wang Liu; Hui Chen; Jia Zhu; Ai-hua Huang; Fei Zhou; Yi Gan; Yan-hua Zhang; Li Ma (Journal of Zhejiang University-SCIENCE B, 2020)

Characteristics of intracellular polyphosphate granules and phosphorus-absorption of a marine polyphosphate-accumulating bacterium, Halomonas sp. YSR-3 - Shiying Ren; Xiangqian Li; Xiulian Yin; Chuping Luo; Fei Liu (Journal of Oceanology and Limnology, 2020)

The phase and code biases of Galileo and BDS-3 BOC signals: effect on ambiguity resolution and precise positioning - Xingxing Li; Xin Li; Gege Liu; Weiliang Xie; Fei Guo; Yongqiang Yuan; Keke Zhang; Guolong Feng (Journal of Geodesy, 2020)

The influence of optimized allocation of agricultural water and soil resources on irrigation and drainage in the Jingdian Irrigation District, China - Jingsi Li; Liangjun Fei; Shan Li; Zhongxing Shi; Lihua Liu (Irrigation Science, 2020)

Research on crack propagation and rock fragmentation efficiency under spherical tooth dynamic indentation - Yong Deng; Fei Yin; Hucheng Deng; Jiang Li; Wei Liu (Arabian Journal of Geosciences, 2020)

Water and heat availability are drivers of the aboveground plant carbon accumulation rate in alpine grasslands on the Tibetan Plateau - Jian Sun; Tian‐Cai Zhou; Miao Liu; You‐Chao Chen; Guo‐Hua Liu; Ming Xu; Pei‐Li Shi; Fei Peng; Atsushi Tsunekawa; Yu Liu; Xiao‐Dan Wang; Shi‐Kui Dong; et al. (Global Ecology and Biogeography, 2020)
Aim Climate change is expected to have important effects on plant phenology and carbon storage, with further shifts predicted in the future. Therefore, we proposed the community carbon accumulation rate (CAR) from the start of the growing season (SOS) to the peak of the growing season (POS) to fill the gap that the dynamic interactions between plant phenology and plant carbon research. Location Tibetan Plateau. Major taxa Alpine grassland plants. Time period 2015. Methods We conducted a transect survey across grasslands to measure community aboveground net primary production and carbon concentration. Additionally, phenology indicator data (SOS and POS) were extracted from the Global Inventory Modeling and Mapping Studies (GIMMS) normalized difference vegetation index version 3 database. Next, we used ‘ changepoint ’ analysis to detect the patterns of CARs, and performed linear regression and one‐way ANOVA to explore the variability of CARs in response to the environmental factors. Ultimately, the total effects of environmental factors on CARs were illustrated by a structural equation model. Results Our results indicated that three CAR patterns were detected, which are low‐CAR (0.15 g/m 2 /day), medium‐CAR (0.31 g/m 2 /day) and high‐CAR (0.84 g/m 2 /day) patterns. We found that the availabilities of water and heat mediated CARs by regulating soil nutrition variability, and that drought climate and insufficient soil resources co‐constrained the community CAR at long time‐scales. In contrast, high CAR could be explained by more water and heat availability via either direct or indirect effects on soil moisture and soil nutrients. Main conclusions Our findings highlight that water and heat availability are critical driving factors in ecological carbon accumulation processes undergoing climate change. Meanwhile, the vegetative phenology also has important effect on carbon accumulation. Consequently, we propose incorporating the dynamic interactions between plant phenology and plant carbon into the ecological carbon cycle model to improve our understanding of resource utilization and survival strategies of plants under environmental change.

Numerical Investigation into the Effect of Damage Openings on Ship Hydrodynamics by the Overset Mesh Technique - Xinlong Zhang; Zhuang Lin; Simone Mancini; Ping Li; Dengke Liu; Fei Liu; Zhanwei Pang (Journal of Marine Science and Engineering, 2019)
Damage stability is difficult to assess due to the complex hydrodynamic phenomena regarding interactions between fluid and structures. Therefore, a detailed analysis of the flooding progression and motion responses is important for improving ship safety. In this paper, numerical simulations are performed on the damaged DTMB 5415 ship at zero speed. All calculation are carried out using CD Adapco Star CCM + software, investigating the effect of damage openings on ship hydrodynamics, including the side damage and the bottom damage. The computational domain is modelled by the overset mesh and solved using the unsteady Reynold-average Navier-Stokes (URANS) solver. An implicit solver is used to find the field of all hydrodynamics unknown quantities, in conjunction with an iterative solver to solve each time step. The Volume of Fluid (VOF) method is applied to visualize the flooding process and capture the complex hydrodynamics behaviors. The simulation results indicated that two damage locations produce the characteristic flooding processes, and the motion responses corresponding to the hydrodynamic behaviors are different. Through comparative analysis, due to the difference between the horizontal impact on the longitudinal bulkhead and the vertical impact on the bottom plate, the bottom damage scenario always has a larger heel angle than the side damage scenario in the same period. However, the pitch motions are basically consistent. Generally, the visualization of the flooding process is efficient to explain the causes of the motion responses. Also, when the damage occurs, regardless of the bottom damage or the side damage, the excessive heel angle due to asymmetric flooding is often a threat to ship survivability with respect to the pitch angle.

Pesticides in the typical agricultural groundwater in Songnen plain, northeast China: occurrence, spatial distribution and health risks - Fuyang Huang; Zeyan Li; Chong Zhang; Théogène Habumugisha; Fei Liu; Ximing Luo (Environmental Geochemistry and Health, 2019)

Effects of stocking density on stress response, innate immune parameters, and welfare of turbot (Scophthalmus maximus) - Baoliang Liu; Fan Fei; Xiaotian Li; Xinyi Wang; Bin Huang (Aquaculture International, 2019)

Environmentally persistent free radicals in PM2.5: a review - Mengxia Xu; Tao Wu; Yu-Ting Tang; Tong Chen; Lavrent Khachatryan; Poornima Ramesh Iyer; Dengting Guo; Anran Chen; Miao Lyu; Jinhu Li; Jiaqi Liu; Dan Li; et al. (Waste Disposal & Sustainable Energy, 2019)

Major advances in studies of the physical geography and living environment of China during the past 70 years and future prospects - Fahu Chen; Bojie Fu; Jun Xia; Duo Wu; Shaohong Wu; Yili Zhang; Hang Sun; Yu Liu; Xiaomin Fang; Boqiang Qin; Xin Li; Tingjun Zhang; et al. (Science China Earth Sciences, 2019)

A novel method for sewage sludge composting using bamboo charcoal as a separating material - Yun-bei Li; Peng-fei Jin; Ting-ting Liu; Jing-hua Lv; Ji-shao Jiang (Environmental Science and Pollution Research, 2019)

Artemisinin suppresses hepatocellular carcinoma cell growth, migration and invasion by targeting cellular bioenergetics and Hippo-YAP signaling - Yujie Li; Jing Lu; Qin Chen; Shengnan Han; Hua Shao; Pingyi Chen; Qiumei Jin; Mingyue Yang; Fugen Shangguan; Mingming Fei; Lu Wang; Yongzhang Liu; et al. (Archives of Toxicology, 2019)

Experimental study on the mechanical properties weakening mechanism of siltstone with different water content - Bingyang Li; Jian Liu; Kang Bian; Fei Ai; Xunjian Hu; Ming Chen; Zhenping Liu (Arabian Journal of Geosciences, 2019)

Development, Optimization, and Evaluation In Vitro/In Vivo of Oral Liquid System for Synchronized Sustained Release of Levodopa/Benserazide - Yang Qu; Wen-Long Lai; Yuan-Rong Xin; Fei-Qin Zhu; Yuan Zhu; Li Wang; Yue-ping Ding; Ying Xu; Hong-Fei Liu (AAPS PharmSciTech, 2019)

Modelling and evaluating the impacts of climate change on three major crops in south-eastern Australia using regional climate model simulations - Bin Wang; De Li Liu; Jason P. Evans; Fei Ji; Cathy Waters; Ian Macadam; Puyu Feng; Kathleen Beyer (Theoretical and Applied Climatology, 2019)

Spatiotemporal characterization of the urban sprawl and its impacts on urban island in China with DMSP/OLS and MODIS measurements - Li Wang; Wenjin Li; Peifa Wang; Xiuyan Liu; Fei Yang; John J Qu (Theoretical and Applied Climatology, 2019)

Failure Mechanisms of Toppling Rock Slopes Using a Three-Dimensional Discontinuous Deformation Analysis Method - Guoyang Liu; Junjie Li; Fei Kang (Rock Mechanics and Rock Engineering, 2019)

Association of the Polymorphism of rs1799822 on Carnitine Palmitoyltransferase II Gene with Severe Enterovirus 71 Encephalitis in Chinese Children - Ya Guo; Yu Zhang; Peipei Liu; Fei Li; Dandan Xin; Hongfang He; Yedan Liu; Chengqing Yang; Zongbo Chen (Journal of Molecular Neuroscience, 2019)

Expression of Ihh signaling pathway in condylar cartilage after bite-raising in adult rats - Hui-qing Long; Peng-fei Tian; Yu-xin Guan; Ling-xia Liu; Xiu-ping Wu; Bing Li (Journal of Molecular Histology, 2019)

Effects of dietary protein level on growth performance, digestive enzyme activity, and gene expressions of the TOR signaling pathway in fingerling Pelteobagrus fulvidraco - Qin Qin; Xiu-Fei Cao; Yong-jun Dai; Li-Na Wang; Ding-Dong Zhang; Guang-Zhen Jiang; Wen-Bin Liu (Fish Physiology and Biochemistry, 2019)

Effect of El Niño on the response ratio of Hadley circulation to different SST meridional structures - Juan Feng; Jianping Li; Fei-Fei Jin; Zhengyu Liu; Sen Zhao (Climate Dynamics, 2019)

LlDREB1G, a novel DREB subfamily gene from Lilium longiflorum, can enhance transgenic Arabidopsis tolerance to multiple abiotic stresses - Baojun Liu; Ying Zhou; Wu Lan; Qin Zhou; Fei Li; Feng Chen; Manzhu Bao; Guofeng Liu (Plant Cell, Tissue and Organ Culture (PCTOC), 2019)

Pathological Alterations of Tau in Alzheimer’s Disease and 3xTg-AD Mouse Brains - Longfei Li; Yanli Jiang; Wen Hu; Yunn Chyn Tung; Chunling Dai; Dandan Chu; Cheng-Xin Gong; Khalid Iqbal; Fei Liu (Molecular Neurobiology, 2019)

Molecular characterization and expression analysis of cyp19a gene in Culter alburnus - Jianbo Zheng; Yongyi Jia; Fei Li; Shili Liu; Meili Chi; Shun Cheng; Zhimi Gu (Fisheries Science, 2019)

Detection and characterization of a novel hepacivirus in long-tailed ground squirrels (Spermophilus undulatus) in China - Li-li Li; Meng-meng Liu; Shu Shen; Yu-jiang Zhang; Ya-long Xu; Hong-yan Deng; Fei Deng; Zhao-jun Duan (Archives of Virology, 2019)

Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo - Fei Xu; Bao Hou; Xuexue Zhu; Yixiao Liu; Xuelin Shi; Shuangshuang Li; Zhongjie Li; Weiwei Cai; Yuetao Zhou; Liying Qiu (Acta Parasitologica, 2019)

Hypermethylation-mediated inactivation of miR-124 predicts poor prognosis and promotes tumor growth at least partially through targeting EZH2/H3K27me3 in ESCC - Ziqiang Tian; Zhenhua Li; Yonggang Zhu; Lingjiao Meng; Fei Liu; Meixiang Sang; Guiying Wang (Clinical & Experimental Metastasis, 2019)

Nonferrous metal (loid) s mediate bacterial diversity in an abandoned mine tailing impoundment - Jianli Liu; Jun Yao; Geoffrey Sunahara; Fei Wang; Zifu Li; Robert Duran (Environmental Science and Pollution Research, 2019)

Effects of soil compaction on plant growth, nutrient absorption, and root respiration in soybean seedlings - Meijiao Wang; Ding He; Fei Shen; Jialing Huang; Rutao Zhang; Wenbo Liu; Mengjue Zhu; Li Zhou; Lihong Wang; Qing Zhou (Environmental Science and Pollution Research, 2019)

Co-expression of fat1 and fat2 in transgenic pigs promotes synthesis of polyunsaturated fatty acids - Fei Tang; Xiaofeng Yang; Dewu Liu; Xianwei Zhang; Xiaoling Huang; Xiaoyan He; Junsong Shi; Zicong Li; Zhenfang Wu (Transgenic Research, 2019)

Proteomics analysis of HSV-1-induced alterations in mouse brain microvascular endothelial cells - Hui Liu; Chu-Xin Huang; Qiang He; Dong Li; Min-Hua Luo; Fei Zhao; Wei Lu (Journal of NeuroVirology, 2019)

Dynamic expressions of hypothalamic genes regulate seasonal breeding in a natural rodent population - Dawei Wang; Ning Li; Lin Tian; Fei Ren; Zhengguang Li; Yan Chen; Lan Liu; Xiangfa Hu; Xuechang Zhang; Ying Song; Roelof A. Hut; Xiao‐Hui Liu (Molecular Ecology, 2019)
Seasonal breeding is a universal reproductive strategy in many animals. Hypothalamic genes, especially type 2 and 3 iodothyronine deiodinases ( Dio2 / 3 ), RFamide‐related peptide 3 ( Rfrp‐3 ), kisspeptin ( Kiss‐1 ) and gonadotropin‐releasing hormone ( GnRH ), are involved in a photoperiodic pathway that encodes seasonal signals from day length in many vertebrate species. However, the seasonal expression patterns of these genes in wild mammals are less studied. Here, we present a four‐year field investigation to reveal seasonal rhythm and age‐dependent reproductive activity in male Brandt's voles ( Lasiopodomys brandtii ) and to detect relationships among seasonal expression profiles of hypothalamic genes, testicular activity, age and annual day length. From breeding season (April) to nonbreeding season (October), adult male voles displayed a synchronous peak in gonadal activity with annual day length around summer solstice, which was jointly caused by age structure shifts and age‐dependent gonadal development patterns. Overwintered males maintained reproductive activity until late in the breeding season, whereas most newborn males terminated gonadal development completely, except for a minority of males born early in spring. Consistently, the synchronous and opposite expression profiles of Dio2/3 suggest their central function to decode photoperiodic signals and to predict the onset of the nonbreeding season. Moreover, changes in Dio2/3 signals may guide the actions of Kiss‐1 and Rfrp‐3 to regulate the age‐dependent divergence of reproductive strategy in wild Brandt's vole. Our results provide evidence on how hypothalamic photoperiod genes regulate seasonal breeding in a natural rodent population.

A Numerical Investigation on the Flooding Process of Multiple Compartments Based on the Volume of Fluid Method - XinLong Zhang; Zhuang Lin; Simone Mancini; Ping Li; Ze Li; Fei Liu (Journal of Marine Science and Engineering, 2019)
A detailed description of the flooding process is crucial to analyze the complex hydrodynamic behaviors and enhance the survivability of the damaged ship. In this paper, through establishing three typical damage scenarios with various locations, the commercial software CD Adapco STAR-CCM+ based on the Reynolds-Averaged Navier-Stokes (RANS) solver is applied to simulate the flooding process involving multiple compartments. The basic computational fluid dynamics (CFD) models and specific simulation settings are elaborated. The volume of fluid (VOF) method combined with the user defined field function is developed to distribute the initial free surface. The captured flooding process indicates that the air compression due to the restricted ventilation decreases the flooding amount. The obtained flooding time can provide necessary data to support for appropriate rescue management and evacuation options.

Dissection of the genetic variation and candidate genes of lint percentage by a genome-wide association study in upland cotton - Chengxiang Song; Wei Li; Xiaoyu Pei; Yangai Liu; Zhongying Ren; Kunlun He; Fei Zhang; Kuan Sun; Xiaojian Zhou; Xiongfeng Ma; Daigang Yang (Theoretical and Applied Genetics, 2019)

Long-term monitoring revealed fish assemblage zonation in the Three Gorges Reservoir - Pengcheng Lin; Xin Gao; Fei Liu; Mingzheng Li; Huanzhang Liu (Journal of Oceanology and Limnology, 2019)

Archaeal community structure in sediments from a seamount in the Mariana Volcanic Arc - Wenyan Zhang; Jia Liu; Yi Dong; Xuegang Li; Cong Xu; Tian Xiao; Hongmiao Pan; Long-Fei Wu (Journal of Oceanology and Limnology, 2019)

Inhibitor of ghrelin receptor reverses gefitinib resistance in lung cancer - Xiaoyou Li; Xia Zhao; Chenchen Li; Siwen Liu; Fei Yan; Yue Teng; Jifeng Feng; Dengshun Miao (Human Cell, 2019)

Identification, evolution and alternative splicing profile analysis of the splicing factor 30 (SPF30) in plant species - Di Zhang; Jing-Fang Yang; Bei Gao; Tie-Yuan Liu; Ge-Fei Hao; Guang-Fu Yang; Li-Jun Fu; Mo-Xian Chen; Jianhua Zhang (Planta, 2019)

Susceptibility of Tribolium castaneum to phosphine in China and functions of cytochrome P450s in phosphine resistance - Yong Huang; Feifan Li; Manwen Liu; Yazhou Wang; Fei Shen; Peian Tang (Journal of Pest Science, 2019)

Effects of periodical drying and non-drying on nutrient content and desiccation tolerance of an intertidal Pyropia yezoensis strain subject to farming conditions - Wen Jun Wang; Xiao Lei Li; Teng Qing Sun; Zhou Rui Liang; Fu Li Liu; Xiu Tao Sun; Fei Jiu Wang (Journal of Applied Phycology, 2019)

Detecting Methylomic Biomarkers of Pediatric Autism in the Peripheral Blood Leukocytes - Xin Feng; Xubing Hao; Ruihao Xin; Xiaoqian Gao; Minge Liu; Fei Li; Yubo Wang; Ruoyao Shi; Shishun Zhao; Fengfeng Zhou (Interdisciplinary Sciences: Computational Life Sciences, 2019)

Post-Collisional, Potassic Volcanism in the Saga Area, Western Tibet: Implications for the Nature of the Mantle Source and Geodynamic Setting - Hui Zhao; Jingsui Yang; Fei Liu; Jian Huang; Li Zhang (Journal of Earth Science, 2019)

Eremophilane sesquiterpenes from the endophytic fungus Xylaria sp. GDG-102 - Yan Liang; Weifeng Xu; Chengmei Liu; Dexiong Zhou; Xiaobo Liu; Yuyue Qin; Fei Cao; Jun Li; Ruiyun Yang; Jiangke Qin (Natural Product Research, 2019)

Serum and Seminal Plasma Element Concentrations in Relation to Semen Quality in Duroc Boars - Ying-hui Wu; Wen Lai; Zi-hui Liu; Hong-kui Wei; Yuan-fei Zhou; Jia-jian Tan; Hai-qing Sun; Sheng-qing Li; Jian Peng (Biological Trace Element Research, 2019)

Dietary supplementation of Streptococcus faecalis benefits the feed utilization, antioxidant capability, innate immunity, and disease resistance of blunt snout bream (Megalobrama amblycephala) - Xiao-Qun Zhong; Ming-Yang Liu; Chao Xu; Wen-Bin Liu; Kenneth-Prudence Abasubong; Xiang-Fei Li (Fish Physiology and Biochemistry, 2019)

Genomic and biological characterization of the Vibrio alginolyticus-infecting “Podoviridae” bacteriophage, vB_ValP_IME271 - Fei Li; Shaozhen Xing; Kaifei Fu; Shuping Zhao; Jianfei Liu; Yigang Tong; Lijun Zhou (Virus Genes, 2019)

Andrographolide impairs alpha-naphthylisothiocyanate-induced cholestatic liver injury in vivo - Lei Wang; Fei Cao; Li-li Zhu; Peng Liu; Yu-ru Shang; Wen-hui Liu; Xin Dong; Hai-dong Bao; Peng Gong; Zhong-yu Wang (Journal of Natural Medicines, 2019)

Synergistic effect and degradation mechanism on Fe-Ni/CNTs for removal of 2,4-dichlorophenol in aqueous solution - Yufeng Sun; Zongtang Liu; Zhenghao Fei; Changshun Li; Yuan Chun; Aimin Zhang (Environmental Science and Pollution Research, 2019)

Two new polyketides from the fungus Penicillium oxalicum MHZ153 - Yi Ren; Ling-Hui Chao; Jing Sun; Xiao-Nan Chen; Hui-Na Yao; Zhi-Xiang Zhu; Dan Dong; Ting Liu; Peng-Fei Tu; Jun Li (Natural Product Research, 2019)

Glucose-6-phosphate dehydrogenase in blunt snout bream Megalobrama amblycephala: molecular characterization, tissue distribution, and the responsiveness to dietary carbohydrate levels - Guang-Zhen Jiang; Hua-Juan Shi; Chao Xu; Ding-Dong Zhang; Wen-Bin Liu; Xiang-Fei Li (Fish Physiology and Biochemistry, 2019)

Ferret badger rabies in Zhejiang, Jiangxi and Taiwan, China - Jing-Hui Zhao; Li-Feng Zhao; Fei Liu; Hong-Yun Jiang; Ji-Li Yang (Archives of Virology, 2019)