Numerical study of steel plate shear walls with diverse construction configurations - Chen Wang; Li-yan Xu; Ling-han Song; Jian-sheng Fan (Engineering Structures, 2023)

Robustness evaluation of the probability-based HTCA model for simulating debris-flow run-out extent: Case study of the 2010 Hongchun event, China - Yangfan Ma; Zheng Han; Yange Li; Guangqi Chen; Weidong Wang; Ningsheng Chen; Guisheng Hu; Lianheng Zhao; Jie Dou (Engineering Geology, 2023)

Fe-ZIF-derived hollow porous carbon nanofibers for electromagnetic wave absorption - Ruiling Sun; Guilong Yan; Xunlong Zhang; Zhenyu Li; Jingyu Chen; Li Wang; Yuanpeng Wu; Yiqun Wang; Han Li (Chemical Engineering Journal, 2023)

An injectable, self-healing composite hydrogel with enhanced near-infrared photo-antibacterial therapeutic effects for accelerated wound healing - Jiameng Wang; Hao Cheng; Weiyi Chen; Peide Han; Xiaohong Yao; Bin Tang; Wangping Duan; Pengcui Li; Xiaochun Wei; Paul K. Chu; Xiangyu Zhang (Chemical Engineering Journal, 2023)

N-type small molecule electron transport materials with D-A-D conjugated core for non-fullerene organic solar cells - Dan Zhou; Yubing Li; Hehui Zhang; Haolan Zheng; Xingxing Shen; Wen You; Lin Hu; Liangjing Han; Yongfen Tong; Lie Chen (Chemical Engineering Journal, 2023)

Prussian Blue@Zeolitic imidazolate framework composite toward solar-triggered biodecontamination - Jie Wang; Xiaojie Ma; Ming Chen; Yuchang Li; Jie Han; Boou Li; Qiuhua Wei; Wenwen Xin; Xiaoping Kang; Jinglin Wang; Bo Wang (Chemical Engineering Journal, 2023)

Slc9a1 plays a vital role in chitosan oligosaccharide transport across the intestinal mucosa of mice - Jiaying Wen; Shengwei Chen; Minglong Bao; Canying Hu; Lianyun Wu; Yanhong Yong; Xiaoxi Liu; Youquan Li; Zhichao Yu; Xingbin Ma; Jong-Bang Eun; Jae-Han Shim; et al. (Carbohydrate Polymers, 2023)

Local and Global Abnormalities in Pre-symptomatic Huntington’s Disease Revealed by 7T Resting-state Functional MRI - Juan-Juan Xie; Xiao-Yan Li; Yi Dong; Cong Chen; Bo-Yi Qu; Shuang Wang; Han Xu; Anna Wang Roe; Hsin-Yi Lai; Zhi-Ying Wu (Neuroscience Bulletin, 2023)

The Nucleus Accumbens CRH–CRHR1 System Mediates Early-Life Stress-Induced Sleep Disturbance and Dendritic Atrophy in the Adult Mouse - Ting Wang; Yu-Nu Ma; Chen-Chen Zhang; Xiao Liu; Ya-Xin Sun; Hong-Li Wang; Han Wang; Yu-Heng Zhong; Yun-Ai Su; Ji-Tao Li; Tian-Mei Si (Neuroscience Bulletin, 2023)

Correction to: Modeling landslide susceptibility using data mining techniques of kernel logistic regression, fuzzy unordered rule induction algorithm, SysFor and random forest - Tingyu Zhang; Quan Fu; Chao Li; Fangfang Liu; Huanyuan Wang; Ling Han; Renata Pacheco Quevedo; Tianqing Chen; Na Lei (Natural Hazards, 2023)

Spatio-temporal changes in daily extreme precipitation for the Lancang–Mekong River Basin - Qiongfang Li; Tianshan Zeng; Qihui Chen; Xingye Han; Xi Weng; Pengfei He; Zhengmo Zhou; Yao Du (Natural Hazards, 2023)

Comparison of the co-occurrence patterns of the gut microbial community between Bt-susceptible and Bt-resistant strains of the rice stem borer, Chilo suppressalis - Geng Chen; Qianwen Li; Xiaowei Yang; Yunhe Li; Wenwen Liu; Fajun Chen; Lanzhi Han (Journal of Pest Science, 2023)

Microplastic pollution and enrichment of distinct microbiota in sediment of mangrove in Zhujiang River estuary, China - Muting Yan; Xiaofeng Chen; Wei Chu; Weixin Li; Minqian Li; Zeming Cai; Han Gong (Journal of Oceanology and Limnology, 2023)

Viperin deficiency promotes dendritic cell activation and function via NF-kappaB activation during Mycobacterium tuberculosis infection - Xinying Zhou; Hui Xu; Qianna Li; Qi Wang; Honglin Liu; Yingqi Huang; Yao Liang; Linmiao Lie; Zhenyu Han; Yaoxin Chen; Yulan Huang; Wenle Zhou; et al. (Inflammation Research, 2023)
Objectives and design Dendritic cells (DCs) are one of the key immune cells in bridging innate and adaptive immune response against Mycobacterium tuberculosis (Mtb) infection. Interferons (IFNs) play important roles in regulating DC activation and function. Virus-inhibitory protein, endoplasmic reticulum-associated, interferon-inducible (Viperin) is one of the important IFN-stimulated genes (ISGs), and elicits host defense against infection. Methods We investigated the effects and mechanisms of Viperin on DC activation and function using Viperin deficient bone marrow-derived dendritic cells (BMDCs) during Mtb infection. Results Viperin deficiency enhanced phagocytic activity and increased clearance of Mtb in DCs, produced higher abundance of NO, cytokine including interleukin-12 (IL-12), Tumor necrosis factor-α (TNF- α ), IL-1 β , IL-6 and chemokine including CXCL1, CXCL2 and CXCL10, elevated MHC I, MHC II and co-stimulatory molecules expression, and enhanced CD4 + and CD8 + T cell responses. Mechanistically, Viperin deficiency promoted DC activation and function through NF-κB p65 activation. NF-κB p65 inhibitor prevented cytokine and chemokine production, and co-stimulatory molecules expression promoted by Viperin deficiency. Conclusions These results suggest that Mtb induced Viperin expression could impair the activation of host defense function of DCs and DC-T cell cross talk during Mtb infection. This research may provide a potential target for future HDT in TB therapy.

Isochrysis sp. cultivation in pilot-scale to concurrently produce sustainable triacylglycerols for human milk fat substitutes and fucoxanthin - Daogui Li; Na Chen; Zhihua Zhou; Cairong Zhong; Jingping Fang; Luqiang Huang; Han Sun; Chengdeng Chi; Youcai Zhou; Yongjin He (Algal Research, 2023)

Mannan oligosaccharide (MOS) on growth performance, immunity, inflammatory and antioxidant responses of the common carp (Cyprinus carpio) under ammonia stress - Shuqun Xue; Banghua Xia; Bitao Zhang; Linyuan Li; Yuning Zou; Zhentao Shen; Yifang Xiang; Ying Han; Weixing Chen (Frontiers in Marine Science, 2022)
This study evaluated the potential effects of mannan oligosaccharide (MOS) on the health status of common carp under ammonia stress. The experimental fish were equally divided into four groups. The control group was fed with a basal diet. The ammonia stress group (Am group) was fed with a basal diet and set in the culture environment with 0.15 mg/L NH3. The MOS group was fed 0.2% MOS with a basal diet. The treatment group (MOS/Am group) was fed 0.2% MOS feed under ammonia exposure (NH3, 0.15 mg/L). These groups were fed for 30 d. The results showed that under ammonia stress, the growth performance decreased significantly, and the activities of non-specific immune factors, intestinal digestive enzymes, and antioxidant enzymes decreased significantly. Dietary supplementation of MOS, the growth performance, the activities of non-specific immune factors, intestinal digestive enzymes, and antioxidant enzymes increased. Histopathological studies showed that adding MOS reduced liver, gill, and intestine tissue damage under ammonia exposure. Our study suggests that adding MOS to the diet can improve growth performance, immunity, antioxidant capacity, and intestinal health of the common carp. MOS can effectively alleviate the oxidative damage and inflammatory response caused by ammonia poisoning to common carp.

The biological transformation of ammonium and urea in a eutrophic estuarine system in Southern China - Jin-Ming Tang; Min Nina Xu; Yuxuan Lin; Huangxin Chen; Haoquan Jin; Li-Li Han; Wenbin Zou; Shuh-Ji Kao (Frontiers in Marine Science, 2022)
Estuaries channel large amounts of anthropogenic nitrogen (N) from continents to the offshore where productivity is widely limited by N and phosphorus. Ammonium and urea, two reduced forms of anthropogenic N commonly observed, are the preferred substrates for various microorganisms (e.g., uptake by phytoplankton or bacteria and oxidation by nitrifier). Yet, it remains underexplored how they transform and their concentrations vary during transport in the estuary which may influence the offshore microbial community. We applied 15 N isotope tracer incubation techniques to determine the two main bio-consumption processes, i.e., uptake and oxidation, of ammonium and urea, in the dark for the Jiulong River Estuary, a eutrophic estuary in southeastern China. Results showed that light penetration depth ranged from 0.8-3.3 m leaving 76% of estuary water bodies to stay in dark situations throughout a day. Ammonia oxidation, which favors dark conditions, dominates the estuarine regenerated-N cycle, showing the rank: ammonia oxidation > ammonium uptake >> urea uptake ≈ urea oxidation. By compiling the reported case studies, we found the relatively low ratio of urea oxidation to ammonia oxidation was accompanied by a relatively high ammonium concentration. Microorganisms’ high preference for ammonium over urea may lead to an inhibitory-like phenomenon. An analogous effect was evident by the increased urea uptake at downstream when ammonium was down to a few µM. The obstructed urea utilization resulted in 10 times longer lifetime for urea relative to ammonium (surface: 19 ± 9 days; bottom 12 ± 7 days). Such an inhibitory-like effect allows urea to be preserved in the estuary and allows urea to be transported farther offshore to stimulate microorganisms capable of utilizing urea, which may have significant impacts on offshore ecology.

Spatial–temporal distribution of large-size light falling-net fisheries in the South China Sea - Jing Qian; Jiajun Li; Kui Zhang; Yongsong Qiu; Yancong Cai; Qiaer Wu; Han Tian; Shengwei Ma; Zuozhi Chen (Frontiers in Marine Science, 2022)
With the rapid modernization of methods for monitoring fishing vessels, different ways of obtaining data on large-size light falling-net vessels have developed. In particular, the vessel monitoring system (VMS) may be used to track fishing activities in the South China Sea (SCS). In this study, we used VMS data to show the characterize and differences in the information transmitted when monitoring large-size falling-net fishing vessels, as well as their advantages and disadvantages. We investigated the spatial distribution of large-size light falling-net fisheries in the SCS using Beidou VMS data from 2017 to 2020. We also compared trajectories of fishing vessels from various provinces. According to these data, vessels operate in the Nansha Islands and the waters of the Pearl River Estuary, Beibu Gulf, Zhongsha, and Xisha Islands, and there is a clear seasonal pattern of fishing in the SCS. There are the differences of vessels in terms of distribution areas and ports of entry and exit. Additionally, we found the operation area of the large-size falling-net fishing vessels divided into four main fishing zones. The analysis compares the number of days of operation in the different fishing areas as well as seasonal variations. Our study shows that the operating area of large-size light falling-net vessels has extended southwards and that the number of days for which fishing vessels operate has increased compared with the last decade. Using the Beidou VMS to study the large-size light falling-net vessels in the SCS can provide more detailed scientific reference data for the SCS fisheries.

QTL analyses of soybean root system architecture revealed genetic relationships with shoot-related traits - Zhili Wang; Cheng Huang; Yongchao Niu; Wai-Shing Yung; Zhixia Xiao; Fuk-Ling Wong; Mingkun Huang; Xin Wang; Chun-Kuen Man; Ching-Ching Sze; Ailin Liu; Qianwen Wang; et al. (Theoretical and Applied Genetics, 2022)

The landscape of aging - Yusheng Cai; Wei Song; Jiaming Li; Ying Jing; Chuqian Liang; Liyuan Zhang; Xia Zhang; Wenhui Zhang; Beibei Liu; Yongpan An; Jingyi Li; Baixue Tang; et al. (Science China Life Sciences, 2022)

Modeling landslide susceptibility using data mining techniques of kernel logistic regression, fuzzy unordered rule induction algorithm, SysFor and random forest - Tingyu Zhang; Quan Fu; Chao Li; Fangfang Liu; Huanyuan Wang; Ling Han; Renata Pacheco Quevedo; Tianqing Chen; Na Lei (Natural Hazards, 2022)

Circ_0003611 regulates apoptosis and oxidative stress injury of Alzheimer’s disease via miR-383-5p/KIF1B axis - Yong Li; Hongli Wang; Li Chen; Kailun Wei; Yang Liu; Yanbai Han; Xuewei Xia (Metabolic Brain Disease, 2022)

Photoacclimation caused by high frequency flashing light assists Chlorella sp. M-12 wastewater treatment and biomass accumulation in dark color biogas slurry - Chaorui Chen; Fan Tao; Ting Han; Fengzheng Gao; Taili Dong; Weizhong Jiang; Haifeng Lu; Yuanhui Zhang; Baoming Li (Journal of Applied Phycology, 2022)

Serum metabolic profiling of coal worker’s pneumoconiosis using untargeted lipidomics - Fangda Peng; Jing Dai; Qingjun Qian; Xiangfu Cao; Lifang Wang; Min Zhu; Shujin Han; Wubin Liu; Yan Li; Teng Xue; Xianyang Chen; Xiaoli Yang; et al. (Environmental Science and Pollution Research, 2022)

Acute Toxicity of a Novel anti-fouling Material Additive DCOIT to Marine Chlorella sp - Jin-Chuang Ru; Xue-Li Zhao; Zhi-Han Cao; Cheng-Zhuang Chen; Ping Li; Zhi-Hua Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Plant diversity is coupled with soil fungal diversity in a natural temperate steppe of northeastern China - Dan Liu; Guohua Liu; Li Chen; Wangya Han; Dongbo Wang (Soil Ecology Letters, 2022)

Study on the Design and Experimental Research on a Bionic Crab Robot with Amphibious Multi-Modal Movement - Xi Chen; Jiawei Li; Shihao Hu; Songjie Han; Kaixin Liu; Biye Pan; Jixin Wang; Gang Wang; Xinmeng Ma (Journal of Marine Science and Engineering, 2022)
Bionic amphibious robots are the intersection of biology and robotics; they have the advantages of environmental adaptability and maneuverability. An amphibious robot that combines walking and swimming move modes inspired by a crab (Portunus) is presented in this article. The outstanding characteristic of the robot is that its environmental adaptability relies on the bionic multi-modal movement, which is based on two modular bionic swimming legs and six modular walking legs. We designed the biomimetic crab robot based on the biological observation results. The design, analysis, and simulation of its structure and motion parameters are introduced in this paper. The swimming propulsion capability and the walking performance are verified through indoor, pool, and seaside experiments. In conclusion, the designed bionic crab robot provides a platform with practical application capabilities in amphibious environment detection, concealed reconnaissance, and aquaculture.

Feasibility Study of a Novel Open Ocean Aquaculture Ship Integrating with a Wind Turbine and an Internal Turret Mooring System - Hanyu Liu; Mingsheng Chen; Zhaolong Han; Hao Zhou; Lin Li (Journal of Marine Science and Engineering, 2022)
Marine aquaculture has been expanded into more remote areas due to the increasing demand for high value-added fish products, bringing more challenges in fuel supply and mooring safety to open ocean aquaculture farms. Therefore, the idea of integrating aquaculture farms with offshore renewable energy has attracted tremendous interest. This study proposes a novel open ocean aquaculture ship integrated with a NREL 5 MW wind turbine. In addition, an internal turret mooring system is installed at the bow of the aquaculture ship, making the wind turbine always face the wind blowing direction due to the weathervaning effect. In this study, a preliminary study of the dynamics and wind power generation of the proposed open ocean aquaculture ship was conducted. The aerodynamic and elastic effects of the wind turbine and the effect of nets under the wave and current behavior on the dynamics of the single-point moored aquaculture ship were investigated. Furthermore, the effects of the dynamics of the aquaculture ship on the power generation of the wind turbine were also studied to investigate the feasibility of the idea to integrate an aquaculture ship with a wind turbine.

Effects of Dietary Tannic Acid on Growth, Digestion, Immunity and Resistance to Ammonia Stress, and Intestinal Microbial Community in Pacific White Shrimp (Litopenaeus vannamei) - Han Gong; Zhen Qin; Zhao Chen; Jitao Li; Zhiqiang Chang; Jian Li; Ping Chen (Fishes, 2022)
Tannic acid (TA) has great potential as a new feed additive. In this study, we investigated the effects of dietary TA on growth, digestion, nonspecific immunity, and resistance to ammonia stress and intestinal microbiota in Litopenaeus vannamei. The shrimp were fed diets containing different levels of TA: 0 mg/kg (TA-0), 200 mg/kg (TA-200), 400 mg/kg (TA-400), and 800 mg/kg (TA-800) for 56 days, followed by acute ammonia stress for 48 h. The results showed that dietary TA increased the survival rate of the TA-800 group. Dietary TA could improve the morphology of the hepatopancreas and intestinal tissues. After feeding different levels of TA for 56 days, the activities of amylase (AMS) and trypsin (Tryp) were increased, but the activity of lipase (LPS) was decreased. The activities of T-AOC, SOD, and PPO were higher in the hepatopancreas of the three TA treatment groups (p

New insights into the molecular mechanism of low-temperature stratification on dormancy release and germination of Saposhnikovia divaricata seeds - Fuyuan Chen; Yulan Huang; Zhenglin Cao; Youzhen Li; Donghui Liu; Xiao Han; Kuide Yin; Quan Liu (Brazilian Journal of Botany, 2022)

Two new phenylpropenoid glycosides from the roots of Illicium dunnianum - Yi-lin Wang; Han Li; Ling Song; Yun-hang Gao; Teng-fei Chen (Natural Product Research, 2022)

Brevilaterin B from Brevibacillus laterosporus has selective antitumor activity and induces apoptosis in epidermal cancer - Zhou Chen; Lulu Wang; Yangliu Liu; Panpan Han; Dan Hong; Siting Li; Aijin Ma; Yingmin Jia (World Journal of Microbiology and Biotechnology, 2022)

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression - Qin Jin; Xiaoyu Yang; Shixue Gou; Xiaoyi Liu; Zhenpeng Zhuang; Yanhui Liang; Hui Shi; Jiayuan Huang; Han Wu; Yu Zhao; Zhen Ouyang; Quanjun Zhang; et al. (Science China Life Sciences, 2022)

Geology, fluid inclusion and H–O–C isotope geochemistry of the Doranasai gold deposit, Chinese Altai: implications for ore genesis - Xun Li; Xiaohua Deng; Wenxiang Liu; Abulimiti Aibai; Xi Chen; Shen Han; Yanshuang Wu; Yanjing Chen (International Journal of Earth Sciences, 2022)

Dongia deserti sp. nov., Isolated from the Gurbantunggut Desert Soil - Chun-Yan Lu; Lei Dong; Dong Wang; Shuai Li; Bao-Zhu Fang; Ming-Xian Han; Feng Liu; Hong-Chen Jiang; Iftikhar Ahmed; Wen-Jun Li (Current Microbiology, 2022)

Centrifuge and numerical modeling of the impact of sediment consolidation induced by capping on contaminant transportation - Jian Zheng; Yu-Chao Li; Han Ke; Yun-Min Chen (Bulletin of Engineering Geology and the Environment, 2022)

RNA sequencing reveals lncRNA-mediated non-mendelian inheritance of feather growth change in chickens - Mohan Qiu; Chunlin Yu; Shiliang Zhu; Siyang Liu; Han Peng; Xia Xiong; Jialei Chen; Xiaosong Jiang; Huarui Du; Qingyun Li; Zengrong Zhang; Chaowu Yang (Genes & Genomics, 2022)
Background Long non-coding RNAs (lncRNAs) play an essential role in biological processes. However, the expression patterns of lncRNAs that regulate the non-Mendelian inheritance feather phenotypes remain unknown. Objective This study aimed to compare the expression profiles of lncRNAs in the follicles of the late-feathering cocks (LC) and late-feathering hens (LH) that followed genetic rules and the early-feathering hen (EH) and early-feathering cock (EC) that did not conform to the genetic laws. Methods We performed RNA sequencing and investigated the differentially expressed lncRNAs (DElncRNAs) between the early- and late-feathering chickens, which function by cis-acting or participate in the competing endogenous RNA (ceRNA) network. Results A total of 53 upregulated and 43 downregulated lncRNAs were identified in EC vs. LC, and 58 upregulated and 109 downregulated lncRNAs were identified in EH vs. LH. The target mRNAs regulated by lncRNAs in cis were enriched in the pentose phosphate pathway, TGF-β signaling pathway and Jak-STAT signaling pathway in EC vs. LC and were associated with the TGF-β signaling pathway, Wnt signaling pathway, p53 signaling pathway and Jak-STAT signaling pathway in EH vs. LH. In addition, the lncRNA-mediated ceRNA regulatory pathways of hair follicle formation were mainly enriched in the TGF-β signaling pathway, Wnt signaling pathway, melanogenesis, and calcium signaling pathways. The levels of ENSGALG00000047626 were significantly higher in the late-feathering chickens than in the early-feathering chickens, which regulated the expression of SSTR2 by gga-miR-1649-5p. Conclusion This study provides a novel molecular mechanism of lncRNA’s response to the feather rate that does not conform to the genetic laws in chickens.

New taxonomic framework for Arthrodermataceae: a comprehensive analysis based on their phylogenetic reconstruction, divergence time estimation, phylogenetic split network, and phylogeography - Zhi-Yuan Zhang; Yu-Lian Ren; Xin Li; Wan-Hao Chen; Jian-Dong Liang; Yan-Feng Han; Zong-Qi Liang (Antonie van Leeuwenhoek, 2022)

Associations between short-term exposure to ambient PM2.5 and incident cases of cerebrovascular disease in Yantai, China - Junyan Liu; Maobo Wang; Yang Zhao; Haotian Chen; Haiyun Liu; Baoshun Yang; Haifeng Shan; Hongyu Li; Yukun Shi; Luyang Wang; Guangcheng Wang; Chunlei Han (Environmental Science and Pollution Research, 2022)

Important revelations of different degrees of COVID-19 lockdown on improving regional air quality: a case study of Shijiazhuang, China - Yanan Guan; Ying Shen; Xinyue Liu; Xuejiao Liu; Jing Chen; Dong Li; Man Xu; Litao Wang; Erhong Duan; Li’an Hou; Jing Han (Environmental Science and Pollution Research, 2022)

Cessation of collisional tectonism and rapid crustal uplift recorded by 430–420 Ma igneous rocks in the South Kunlun belt, northwest China - Jing Chen; Bing-Zhang Wang; Fu-Cheng Yu; Jie Han; Wu-Fu Li (International Geology Review, 2022)

The spatial distribution and characterization of phosphorus and nitrogen in a water-carrying lake: a case study of Lake Jiaogang, China - Tianlun Han; Kang Zhou; Jiuling Li; Ting Chen; Xueting Xu; Shuai Zhang; Jianying Chao; Ming Kong (Environmental Science and Pollution Research, 2022)

Decadal Changes in the Annual Growth of Two Commercial Ommastrephid Species in the Pacific Ocean - Peiwu Han; Jianhua Li; Yating Dan; Bilin Liu; Xinjun Chen; Zhou Fang (Fishes, 2022)
Neon flying squid Ommastrephes bartramii and jumbo flying squid Dosidicus gigas are two important commercial ommastrephid species in the Pacific Ocean. As short-lived marine species, squids are highly susceptible to changes in climate and marine environments. According to samples collected from the northwest and southeast Pacific Ocean in different years, we explored the growth characteristics of these two squids in terms of their mantle length (ML) distribution and the relationship between mantle length and body weight (LWR), also considering the relative condition factors (Kn), and explored the effects of the El Niño and Southern Oscillation (ENSO) on their growth. The results showed that the ML for O. bartramii and D. gigas had significant differences among different years and different sexes (p 3), and parameters a and b were influenced by year and sex. Furthermore, there were significant differences in Kn in both squids for different years and different sexes (p

The strigolactone receptor SlDWARF14 plays a role in photosynthetic pigment accumulation and photosynthesis in tomato - Zhifei Li; Ying Pi; Changsheng Zhai; Dong Xu; Wenyao Ma; Hong Chen; Yi Li; Han Wu (Plant Cell Reports, 2022)

miR-383-5p Regulated by the Transcription Factor CTCF Affects Neuronal Impairment in Cerebral Ischemia by Mediating Deacetylase HDAC9 Activity - Jun Shen; Qiu Han; Wangjun Li; Xiaochang Chen; Jingmin Lu; Jinyu Zheng; Shouru Xue (Molecular Neurobiology, 2022)

Pseudoephedrine hydrochloride causes hyperactivity in zebrafish via modulation of the serotonin pathway - Yini Zhou; Tonglaga Li; Shangzi Zhou; Han Xu; Xiaoyu Yin; Hao Chen; Xuan Ni; Meirong Bai; Wuliji Ao; Jingfeng Yang; R. G. Ahmed; Xuefu Zhang; et al. (Metabolic Brain Disease, 2022)

Urinary cadmium and peripheral blood telomere length predict the risk of renal function impairment: a study of 547 community residents of Shanxi, China - Jia-Chen Zhang; Shuang-Jing Li; Jian-Yong Guo; Guo-Yan Zhang; Hui Kang; Xiu-Jing Shi; Han Zhou; Yu-Fen Liang; Wei-Tong Shen; Li-Jian Lei (Environmental Science and Pollution Research, 2022)

Investigation of thermal-hydro-mechanical coupled fracture propagation considering rock damage - Kaituo Jiao; Dongxu Han; Daobing Wang; Yujie Chen; Jingfa Li; Liang Gong; Bofeng Bai; Bo Yu (Computational Geosciences, 2022)

Facial emotion perception abilities are related to grey matter volume in the culmen of cerebellum anterior lobe in drug-naïve patients with first-episode schizophrenia - Xiaoxin Zhao; Jingjing Yao; Yiding Lv; Xinyue Zhang; Chongyang Han; Lijun Chen; Fangfang Ren; Qun Zhou; Zhuma Jin; Yuan Li; Yasong Du; Yuxiu Sui (Brain Imaging and Behavior, 2022)

Toward real-time construction of global ionosphere map from ground and space-borne observations - Yi Han; Lei Wang; Ruizhi Chen; Wenju Fu; Tao Li; Haitao Zhou (GPS Solutions, 2022)

Streptococcus humanilactis sp.nov., isolated from healthy nursing mother's breast milk - Xiaoqing Guo; Fei Han; Lin Cong; Yu Li; Yue Wu; Chen Liu; Jingfang Yang; Risu Na; Wenjun Liu (Archives of Microbiology, 2022)

Paracandidimonas lactea sp. nov., a urea-utilizing bacterium isolated from landfill - Chu Zhang; Qian Pu; Jun-jie Ying; Ying Chen; Cheng-ze Li; Hang-tao Wu; Bin-jie Wang; Yu-han Zhang; Guo-hong Zeng; Ou Li; Xiu-fang Hu; Cong Sun (Archives of Microbiology, 2022)

Development of 45 SNP markers in Triplophysa hsutschouensis based on RAD sequencing - Ya Liu; Jiansheng Lai; Zhongmeng Zhao; Hongyu Ke; Han Zhao; Yeyu Chen; Xiaoyun Wu; Qiang Li (Conservation Genetics Resources, 2022)

Experimental Investigation and Numerical Modeling of Two-Phase Flow Development and Flow-Induced Vibration of a Multi-Plane Subsea Jumper - Wenhua Li; Qing Zhou; Guang Yin; Muk Chen Ong; Gen Li; Fenghui Han (Journal of Marine Science and Engineering, 2022)
As an essential component in the offshore oil and gas industry, subsea jumpers are likely to encounter the cyclic-induced stresses caused by the alternating movement of gas plugs and liquid slugs while transporting a multiphase mixture. The present study investigates the gas-liquid flow and the induced vibration in a multi-plane jumper by adopting experimental and numerical techniques. The flow patterns at every characteristic section of a Z-shaped jumper with an inner diameter of 48 mm are experimentally investigated, including dispersed bubbly, slug, churn, wavy, stratified and annular flows. Displacement and pressure sensors are installed near each elbow to record the vibration and pressure response of the jumper. It is found that both pressure characteristics and vibration amplitudes are highly related to the gas content rate, mixing velocity, and gas and liquid superficial velocity. The one-way fluid–solid coupling numerical simulations are performed and validated against the experimental data in terms of the flow patterns and the induced vibrations at different gas–liquid velocities. The results reveal that both simulated flow patterns and vibration responses agree well with the experiments.

Cassane diterpenoids from Caesalpinia pulcherrima and their anti-inflammatory and α -glycosidase inhibitory activities - Xin Yun; Xiu-Mei Chen; Jia-Yun Wang; Wang Lu; Zi-Han Zhang; Young Ho Kim; Shi-Chun Zong; Chun-Huan Li; Jin-Ming Gao (Natural Product Research, 2022)

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Impacts of climate and reservoirs on the downstream design flood hydrograph: a case study of Yichang Station - Rongrong Li; Lihua Xiong; Xini Zha; Bin Xiong; Han Liu; Jie Chen; Ling Zeng; Wenbin Li (Natural Hazards, 2022)

Validity Analysis of the Morphological Identification of Three Highly Morphologically Similar Species Belonging to the Genus Niviventer (Rodentia: Muridae) - Yao-Yao Li; Hao-Tian Li; Jia-Wei Hao; Chen-Yi Zhang; Guan-Ze Liu; Xing-Han Lin; Xiao-Qing Sun; Guo-Chen Zang; Yu-Chun Li (Journal of Mammalian Evolution, 2022)

Composition and indication of plankton fatty acids under the influence of environmental factors in the Hongfeng Reservoir, Southwest China - Xing Wang; Qiuhua Li; Wenshen Chen; Mengshu Han; Libin Han; Anton Brancelj (Aquatic Ecology, 2022)

Dental follicle cells show potential for treating Parkinson’s disease through dopaminergic-neuronogenic differentiation - Fei Bi; Jie Xiong; Xue Han; Chao Yang; Xinghan Li; Guoqing Chen; Weihua Guo; Weidong Tian (Human Cell, 2022)

Study of Two Ships Approaching Process and Towing Motion under Wave Action - Shengtao Chen; Han Zou; Guocai Qi; Dongju Li; Zhouyuan Xu (Journal of Marine Science and Engineering, 2022)
The rescue of ships in distress at sea relies mainly on rescue vessels, which includes the approaching process and the towing motion of the two ships. Ship rescue can be reduced to a two-ship problem, primarily involving the relative motion between ships during rescue. We established a mathematical model of ship motion based on the viscous fluid N-S equation, and the approaching process of two Wigley ships under waves was simulated in a two-dimensional plane. Then, according to three-dimensional potential flow theory, the coupled motion response model of the ships under six degrees of freedom was constructed, and calculation models of wind, waves, currents and other environmental disturbance factors were established to numerically calculate the towing motion. The results show that the upstream vessel has a lower heave motion amplitude and higher roll motion amplitude during the approaching process; A ratio of 1.5 times the width of the ship is the critical area where the motion of the two ships interacts with each other; For the berthing process, the faster the motion of the active vessel is, the lower the motion amplitude will be for both upstream and downstream vessels. When towing under rough sea conditions, changes in wave height and towing velocity have a large influence on the coupling effect of the towing system. When towing, head-on waves and low sea conditions are preferred, and the velocity should be sufficiently high to reduce the influence of cable self-weight on the towed ship. According to the simulations, the recommended velocity range is 3–5 m/s. Finally, a ship model scaling model was developed based on the similar quasi-Froude number of the ship model test, and the simulation results were verified by conducting parallel and towing tests of the model in a basin with a spherical wave-maker device.

PTEN-induced kinase 1 enhances the reparative effects of bone marrow mesenchymal stromal cells on mice with renal ischaemia/reperfusion-induced acute kidney injury - Chenyu Lin; Wen Chen; Yong Han; Yujie Sun; Xiaoqiong Zhao; Yuan Yue; Binyu Li; Wenmei Fan; Tao Zhang; Li Xiao (Human Cell, 2022)
Acute kidney injury (AKI) is a common severe acute syndrome caused by multiple factors and is characterized by a rapid decline in renal function during a short period. Bone marrow mesenchymal stromal cells (BMSCs) are effective in treating AKI. However, the mechanism of their beneficial effects remains unclear. PTEN-induced kinase 1 (PINK1) may play an important role in kidney tissue repair. In this study, we explored the effect of PINK1 overexpression on enhancing BMSC-mediated repair of AKI. In this study, ischaemia/reperfusion-induced AKI (IRI-AKI) in mice and a hypoxia-reoxygenation model in cells were established, and the indices were examined by pathology and immunology experiments. After ischaemia/reperfusion, PINK1 overexpression reduced apoptosis in injured kidney tissue cell, decreased T lymphocyte infiltration, increased macrophage infiltration, and alleviated the inflammatory response. PINK1 relieved the stress response of BMSCs and renal tubular epithelial cells (RTECs), reduced apoptosis, altered the release of inflammatory factors, and reduced the proliferation of peripheral blood mononuclear cells (PBMCs). In conclusion, BMSCs and RTECs undergo stress responses in response to hypoxia, inflammation and other conditions, and overexpressing PINK1 in BMSCs could enhance their ability to resist these stress reactions. Furthermore, PINK1 overexpression can regulate the distribution of immune cells and improve the inflammatory response. The regulation of mitochondrial autophagy during IRI-AKI maintains mitochondrial homeostasis and protects renal function. The results of this study provide new strategies and experimental evidence for BMSC-mediated repair of IRI-AKI.

Effects of land use/cover change on atmospheric humidity in three urban agglomerations in the Yangtze River Economic Belt, China - Baoni Li; Lihua Xiong; Quan Zhang; Shilei Chen; Han Yang; Shuhui Guo (Natural Hazards, 2022)

Correction to: Exosome-Derived lncRNA NEAT1 Exacerbates Sepsis-Associated Encephalopathy by Promoting Ferroptosis Through Regulating miR-9-5p/ TFRC and GOT1 Axis - Xue-biao Wei; Wen-qiang Jiang; Ju-hao Zeng; Lin-qiang Huang; Hong-guang Ding; Yuan-wen Jing; Yong-li Han; Yi-chen Li; Sheng-long Chen (Molecular Neurobiology, 2022)

Responses of rice (Oryza sativa L.) plant growth, grain yield and quality, and soil properties to the microplastic occurrence in paddy soil - Sen Chen; Yanfang Feng; Lanfang Han; Detian Li; Yuanyuan Feng; Paramsothy Jeyakumar; Haijun Sun; Weiming Shi; Hailong Wang (Journal of Soils and Sediments, 2022)

Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment - Jiehui Jiang; Can Sheng; Guanqun Chen; Chunhua Liu; Shichen Jin; Lanlan Li; Xueyan Jiang; Ying Han; Michael W. Weiner; Paul Aisen; Ronald Petersen; Clifford R. Jack; et al. (GeroScience, 2022)

Comprehensive analysis of a paleo-landslide damming event on the upper reach of the Jinsha River, SE Tibetan Plateau - Yuchao Li; Jianping Chen; Zhihai Li; Xudong Han; Shijie Zhai; Yongchao Li; Yiwei Zhang; Feifan Gu (Bulletin of Engineering Geology and the Environment, 2022)

Comparative study on characteristics of mandarin peel extracts by biological processing - Jiamin Chen; Xinling Han; Yulai Wu; Lu Liu; Jianxing Yu; Jiayou Li; Yang Zhang; Yaling Xu (Archives of Microbiology, 2022)

Interval-Valued Fuzzy Multi-Criteria Decision-Making with Dependent Evaluation Criteria for Evaluating Service Performance of International Container Ports - Yu-Jie Wang; Li-Jen Liu; Tzeu-Chen Han (Journal of Marine Science and Engineering, 2022)
Due to COVID-19 barriers, the needs of international container ports have become more important than in the past. Therefore, it is very critical and essential for the scientific developments of port-logistics. To gain the scientific developments of port logistics, effective and efficient evaluation methods for decision-making are indispensable, especially for assessing service performance of international container ports based on dependent evaluation criteria (DEC). Among numerous decision-making methods, technique for order preference by similarity to ideal solution (TOPSIS) was often expanded under fuzzy environments into fuzzy multi-criteria decision-making (FMCDM) to preserve imprecise messages. The FMCDM was able to be associated with quality function deployment (QFD) into a hybrid method to solve problems with DEC. To gain more messages, QFD and TOPSIS are combined and then expanded under interval-valued fuzzy environment (IVFE) to solve a FMCDM problem with DEC. Practically, evaluating service performance of international container ports in Taiwan and the surrounding sea areas is considered a problem with DEC because the related evaluation criteria are partially connected. By the hybrid method of combining QFD with TOPSIS under IVFE, international container ports with DEC are effectively and efficiently evaluated for service performance, and more insights are gained than the past for establishing essential fundamentals in recent scientific developments of port logistics on account of breaking down COVID-19 barriers.

Species and Functional Dynamics of the Demersal Fish Community and Responses to Disturbances in the Pearl River Estuary - Zeyu Zeng; William W. L. Cheung; Han Lai; Huadong Yi; Sheng Bi; Haiyang Li; Xiaoli Chen; Yuqin Su; Xuange Liu; Qiuxian Chen; Zhilun Zhang; Xuchong Wei; et al. (Frontiers in Marine Science, 2022)
Fishery resources are threatened by environmental changes and anthropogenic pressures, particularly in coastal ecosystems. It is crucial to understand the changes of fish communities and their responses to environmental changes and human disturbances to formulate rational fisheries and ecosystem-based management. The Pearl River Estuary (PRE) is a typical sub-tropic coastal ecosystem located in the center of the Guangdong-Hong Kong-Macao Greater Bay Area in the northern South China Sea. The demersal fish in the PRE is traditionally targeted as commercial fishing and severely impacted by overexploitation and hypoxia in the last few decades. In this study, we analyze the fish survey data during the period of 2020~2021 using multivariate statistics to investigate the impacts of human disturbances on the species and functional dynamics of the demersal fish community in the PRE. The results reveal that dissolved oxygen and temperature have significant correlations with the functional traits of the demersal fish community. The impacts of hypoxia on the demersal fish vary with species and locations. We found that the mean functional redundancy of the demersal fish community in the PRE was high across three surveys, but the functional diversity was low in this region. The abundance and richness of the demersal fish community increased during the summer fishing moratorium in the South China Sea in 2021, but the functional diversity did not increase significantly. We conclude that the high functional redundancy in the PRE might not be sufficient to buffer against environmental disturbances because of its low functional diversity. Our study highlights the complicated interactions between the demersal fish community and disturbances in the PRE. Understanding the traits structure and functional diversity of the fish community can help elucidate the factors determining the dynamic responses of the fish community to disturbances.

Visible Particle Identification Using Raman Spectroscopy and Machine Learning - Han Sheng; Yinping Zhao; Xiangan Long; Liwen Chen; Bei Li; Yiyan Fei; Lan Mi; Jiong Ma (AAPS PharmSciTech, 2022)

Iron loss of paddy soil in China and its environmental implications - Liumei Chen; Dongbo Zhao; Guangzhong Han; Fei Yang; Zitong Gong; Xiaodong Song; Decheng Li; Ganlin Zhang (Science China Earth Sciences, 2022)

The key environmental factors driving the succession of phytoplankton functional groups in Hongfeng Reservoir, southwest China - Libin Han; Qiuhua Li; Wensheng Chen; Xing Wang; Shihui Zhou; Mengshu Han; Anton Brancelj (Journal of Oceanology and Limnology, 2022)

Identification of a major stable QTL for spikelet number in wheat (Triticum aestivum L.) and its genetic effects analysis on yield-related traits - Mingsu Cao; Jizi Dong; Hao Wang; Yibiao Cai; Tianhang Ma; Xiaohan Zhou; Jingguo Xiao; Shihui Li; Linqu Chen; Huiyuan Xu; Chunhua Zhao; Yongzhen Wu; et al. (Euphytica, 2022)

Brevibacillus dissolubilis sp. nov., Isolated from Fresh Water - Wei Li; Zhao-Xuan Wang; Fu Ma; Zhi-Da Zi; Han-Yi Chen; De Zhou; Jie Lv (Current Microbiology, 2022)

Grain size-dependent geochemical evidence reveals provenance and implications of aeolian sands, Dinggye region, southern Tibet - You-gui Chen; Mei-hui Pan; Ze-wen Hao; Yu-han Qi; Chen-lu Li (Journal of Mountain Science, 2022)

Development and perspectives of rapid detection technology in food and environment - Xue-Xia Jia; Shuang Li; Dian-Peng Han; Rui-peng Chen; Zi-Yi Yao; Bao-an Ning; Zhi-Xian Gao; Zhen-Chuan Fan (Critical Reviews in Food Science and Nutrition, 2022)

High On-Treatment Platelet Reactivity as Predictor of Long-term Clinical Outcomes in Stroke Patients with Antiplatelet Agents - Huihui Lv; Zidong Yang; Haibo Wu; Mingyuan Liu; Xiaowei Mao; Xu Liu; Hongyan Ding; Zhuqing Shi; Yang Zhou; Qianyun Liu; Yongkang Zhang; Yinting Zhou; et al. (Translational Stroke Research, 2022)

Structural variability in the bulk soil, rhizosphere, and root endophyte fungal communities of Themeda japonica plants under different grades of karst rocky desertification - Ming Tang; Jie Liu; Wenpeng Hou; Reed M. Stubbendieck; Han Xiong; Jie Jin; Jiyi Gong; Chen Cheng; Xiaoxin Tang; Yinglong Liu; Zhaofeng Li; Jianfeng Wang; et al. (Plant and Soil, 2022)

Impact of CT-Based and MRI-Based Attenuation Correction Methods on 18 F-FDG PET Quantification Using PET Phantoms - Cheng-Han Wu; Chun-Yuan Tu; Li-Chen Shen; Yueh-Hsun Lu; Bang-Hung Yang (Journal of Medical and Biological Engineering, 2022)

Experimental investigation of the hydraulic properties of large-scale irregular fractured rock masses in granite fault zones - Liang Guo; Xiaoyu He; Zhuhong Xiong; Han Chen; Jiao Zhu; Mingwei Liao; Hao Guo; Xiaozhao Li; Baoquan Wang; Min Zhang; Lei Xing (Hydrogeology Journal, 2022)

C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population - Feifei Han; Lu Qian; Yi Zhang; Ping Liu; Rui Li; Mingwei Chen (Functional & Integrative Genomics, 2022)

Knowledge domain and research progress in green consumption: a phase upgrade study - Han Huang; Ruyin Long; Hong Chen; Qianwen Li; Meifen Wu; Xin Gan (Environmental Science and Pollution Research, 2022)

Is the “pollution haven hypothesis” valid for China’s carbon trading system? A re-examination based on inter-provincial carbon emission transfer - Xin Nie; Zhoupeng Chen; Han Wang; Jianxian Wu; Xingyi Wu; Bo Lu; Li Qiu; Yuanyuan Li (Environmental Science and Pollution Research, 2022)

A novel information changing rate and conditional mutual information-based input feature selection method for artificial intelligence drought prediction models - Qiongfang Li; Xingye Han; Zhennan Liu; Pengfei He; Peng Shi; Qihui Chen; Furan Du (Climate Dynamics, 2022)

Multivariate morphological brain signatures enable individualized prediction of dispositional need for closure - Xinling Chen; Zhenhua Xu; Ting Li; Li Wang; Peiyi Li; Han Xu; Chunliang Feng; Chao Liu (Brain Imaging and Behavior, 2022)

Early-Holocene Paleo-Tropical Cyclone Activity Inferred from a Sedimentary Sequence in South Yellow Sea, East Asia - Geng Liu; Xibin Han; Yanping Chen; Jun Li; Lehui Song; Xin Zhou; Bangqi Hu; Liang Yi (Journal of Earth Science, 2022)

Isolation and characterization of 45 SNP markers in Triplophysa tenuis - Ya Liu; Yeyu Chen; Jiansheng Lai; Hongyu Ke; Zhongmeng Zhao; Han Zhao; Xiaoyun Wu; Jian Zhou; Qiang Li (Conservation Genetics Resources, 2022)

Response Process of Coastal Hypoxia to a Passing Typhoon in the East China Sea - Qicheng Meng; Feng Zhou; Xiao Ma; Jiliang Xuan; Han Zhang; Shuai Wang; Xiaobo Ni; Wenyan Zhang; Bin Wang; Dewang Li; Di Tian; Jia Li; et al. (Frontiers in Marine Science, 2022)
Details of the development of coastal hypoxia in response to the passage of Typhoon Bavi (2020) in the East China Sea were reconstructed by numerical modeling using a three-dimensional coupled physical–biogeochemical model. The model was validated via repeated surveys along a transect across a submerged river valley off the Changjiang Estuary before and after the passage of Typhoon Bavi. Before Bavi’s arrival, survey data indicated that the coastal hypoxia had formed off the Changjiang Estuary. However, the hypoxia was not eliminated but instead migrated and aggravated along the observed transect after the typhoon passage. This phenomenon cannot be attributed to the typhoon-induced mixing. Simulation results reveal that the observed development and spatial migration of hypoxia was mainly controlled by typhoon-induced oceanic advection. Results show that Bavi stimulated a regional quasi-barotropic cyclonic loop circulation and coastal downwelling reversing general summer circulation patterns. The onshore transport of the warmer shelf water and subsequent downwelling resulted in a warming of coastal water. The southward coastal current and downwelling induced by the typhoon also led to a migration of the hypoxic zone. Meanwhile, a massive transport of resuspended planktonic detritus from the steep inner shelf and the shallow Changjiang bank toward the submerged river valley occurred. This study reveals that the typhoon-driven currents can play an important role in the development of hypoxia and redistribution of deposited organic matter in coastal shelf seas, which may have both short- and long-term effects on the regional marine biogeochemical environment.

A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam - Yi-Fan Yu; Yue-Qian Li; Ru-Yue Wang; Xu Liu; Wen-Bo Cui; Xiao-Han Chen; Cheng-Mu Zhao; Feng-Ming Qi; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

Exogenous artificial DNA forms chromatin structure with active transcription in yeast - Jianting Zhou; Chao Zhang; Ran Wei; Mingzhe Han; Songduo Wang; Kaiguang Yang; Lihua Zhang; Weigang Chen; Mingzhang Wen; Cheng Li; Wei Tao; Ying-Jin Yuan (Science China Life Sciences, 2022)
Yeast artificial chromosomes (YACs) are important tools for sequencing, gene cloning, and transferring large quantities of genetic information. However, the structure and activity of YAC chromatin, as well as the unintended impacts of introducing foreign DNA sequences on DNA-associated biochemical events, have not been widely explored. Here, we showed that abundant genetic elements like TATA box and transcription factor-binding motifs occurred unintentionally in a previously reported data-carrying chromosome (dChr). In addition, we used state-of-the-art sequencing technologies to comprehensively profile the genetic, epigenetic, transcriptional, and proteomic characteristics of the exogenous dChr. We found that the data-carrying DNA formed active chromatin with high chromatin accessibility and H3K4 tri-methylation levels. The dChr also displayed highly pervasive transcriptional ability and transcribed hundreds of noncoding RNAs. The results demonstrated that exogenous artificial chromosomes formed chromatin structures and did not remain as naked or loose plasmids. A better understanding of the YAC chromatin nature will improve our ability to design better data-storage chromosomes.

First report of Botryosphaeria dothidea causing leaf blotch of Mahonia bealei in China - Yi-Jia Cao; Rong-Han Chen; Yuan-Zhi Si; Li-Hua Zhu (Journal of Plant Pathology, 2022)

Analysis on ecological status and spatial–temporal variation of Tamarix chinensis forest based on spectral characteristics and remote sensing vegetation indices - Jin Wang; Ping Han; Yanhua Zhang; Jinyu Li; Linxu Xu; Xue Shen; Zhigang Yang; Sisi Xu; Guangxue Li; Feiyong Chen (Environmental Science and Pollution Research, 2022)

Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities - Ying-Ying Chen; Jiang-Ping Hou; Ling Huang; Afsar Khan; Fei-Fei Xing; Xiao-Han Zhang; De-Feng Han; Shi-Li Yan; Gui-Dong Cao; Qi-Yang Jiao; Dejie Liu; Xuwei Zhu; et al. (Natural Product Research, 2022)

Enhanced genome editing to ameliorate a genetic metabolic liver disease through co-delivery of adeno-associated virus receptor - Shuming Yin; Lie Ma; Tingting Shao; Mei Zhang; Yuting Guan; Liren Wang; Yaqiang Hu; Xi Chen; Honghui Han; Nan Shen; Wenjuan Qiu; Hongquan Geng; et al. (Science China Life Sciences, 2022)

Overexpression of Cpg15 Alleviates the Oxidative Stress in Neuronal Cells Via Regulating Redox Enzymes and Nrf2 Antioxidative Pathway - Yi Jiang; Jun-Jie Li; Ya-Wei Mu; Han-Yang Jiang; Zi-Xuan Wei; Zi-Yao Xiao; Jing-Jing Zhao; Xian-Hua Chen (Neurotoxicity Research, 2022)

Exploring the Potential Antidepressant Mechanisms of Pinellia by Using the Network Pharmacology and Molecular Docking - Yu-Gang Xiao; Han-Biao Wu; Ji-Sheng Chen; Xiong Li; Zhi-Kun Qiu (Metabolic Brain Disease, 2022)

Measurement of atmospheric conductivity on the Qinghai-Tibet Plateau in China - Lei Li; Jianfeng Su; Tao Chen; Shuo Ti; Han Wu; Jing Luo; Wen Li; Renkang Li (Meteorology and Atmospheric Physics, 2022)

Ziprasidone suppresses pancreatic adenocarcinoma cell proliferation by targeting GOT1 to trigger glutamine metabolism reprogramming - Yueying Yang; Mengzhu Zheng; Fei Han; Lei Shang; Mingxue Li; Xiaoxia Gu; Hua Li; Lixia Chen (Journal of Molecular Medicine, 2022)

Dihydroartemisinin ameliorates chronic nonbacterial prostatitis and epithelial cellular inflammation by blocking the E2F7/HIF1α pathway - Yan Zhou; Jun-hao Wang; Jian-peng Han; Jian-yong Feng; Kuo Guo; Fei Du; Wen-bin Chen; Yong-zhang Li (Inflammation Research, 2022)

Migration Route Reconstruction of Different Cohorts of Ommastrephes bartramii in the North Pacific Based on Statolith Microchemistry - Peiwu Han; Zhou Fang; Nan Li; Xinjun Chen (Frontiers in Marine Science, 2022)
Ommastrephes bartramii is one of the important commercial fishery species in the North Pacific Ocean. It always migrates for a long distance in order to spawning and feeding. Understanding its migration route can be the basis for the sustainable development of the fisheries and scientific management of this species. Cephalopod statoliths contain a wealth of ecological information, which can provide useful information for studying spatio-temporal distribution. In this study, the statolith elements of winter-spring and autumn cohorts of O. bartramii in the North Pacific Ocean were measured by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The differences in both composition and concentrations of elements between winter-spring and autumn cohorts were analyzed and the migration route were reconstructed. The analysis showed that the highest concentrations of elements in different cohorts was calcium (Ca). The concentrations of Ca, strontium (Sr), sodium (Na), iron (Fe), barium (Ba), and lithium (Li) showed significant differences between two cohorts ( P < 0.01). Mg, Ba, Sr, and Na were selected as the key elements in the two cohorts based on random forest method. Five clusters were obtained through chronological clustering, representing the five ontogenetic stages. Different cohorts selected different elements to fit the regression model with the corresponding water temperature. The high probability of occurrence in a particular area represented the possible optimal squid location based on a Bayesian model, and the potential migration routes of the different cohorts were reconstructed. This study shows that statoliths microchemistry can provide useful information for identifying the distribution and migration of oceanic squid.

A new isoflavone from the fruits of Ficus auriculata and its antibacterial activity - Tai-Ming Shao; Hai-Xia Liao; Xiao-Bao Li; Guang-Ying Chen; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2022)

Exosome-Derived lncRNA NEAT1 Exacerbates Sepsis-Associated Encephalopathy by Promoting Ferroptosis Through Regulating miR-9-5p/TFRC and GOT1 Axis - Xue-biao Wei; Wen-qiang Jiang; Ju-hao Zeng; Lin-qiang Huang; Hong-guang Ding; Yuan-wen Jing; Yong-li Han; Yi-chen Li; Sheng-long Chen (Molecular Neurobiology, 2022)
Sepsis can cause sepsis-associated encephalopathy (SAE), but whether SAE was induced or exacerbated by ferroptosis remains unknown. In this study, the rat sepsis model was constructed using the cecal ligation and puncture method. The blood–brain barrier (BBB) permeability was measured by Evans blue dye (EBD) in vivo. The levels of ROS, Fe ion, MDA, GSH, and GPX4 were assessed by enzyme-linked immunosorbent assay (ELISA). The exosomes isolated from serum were cultured with bEnd.3 cells for the in vitro analysis. Moreover, bEnd.3 cells cultured with 100 μM FeCl3 (iron-rich) were to simulate ferroptosis stress. The cell viability was evaluated by Cell Counting Kit-8 (CCK-8) assay. A dual-luciferase reporter gene assay was performed to confirm the relationship between miR-9-5p with NEAT1, TFRC , and GOT1 . In vivo, it is found that BBB permeability was damaged in model rats. Level of ROS, Fe ion, and MDA was increased, and level of GSH and GPX4 was decreased, which means ferroptosis was induced by sepsis. Exosome-packaged NEAT1 in serum was significantly upregulated in model rats. In vitro, it is found that NEAT1 functions as a ceRNA for miR-9-5p to facilitate TFRC and GOT1 expression. Overexpression of NEAT1 enhanced ferroptosis stress in bEnd.3 cells. Increased miR-9-5p alleviated sepsis-induced ferroptosis by suppressing the expression of TFRC and GOT1 both in vivo and in vitro. In conclusion, these findings suggest that sepsis induced high expression of serous exosome-derived NEAT1, and it might exacerbate SAE by promoting ferroptosis through regulating miR-9-5p/ TFRC and GOT1 axis.

Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components - Tingting Lin; Jiaqi Tao; Ying Chen; Yitong Zhang; Fenglan Li; Yutong Zhang; Xueqing Han; Zihui Zhao; Guiyan Liu; Hui Li (Biological Trace Element Research, 2022)

Anaerobic digestion characteristics and key microorganisms associated with low-temperature rapeseed cake and sheep manure fermentation - Li Liu; Rongbo Xiong; Yi Li; Laisheng Chen; Rui Han (Archives of Microbiology, 2022)

Extracellular Vesicle Application as a Novel Therapeutic Strategy for Ischemic Stroke - Yiyang Li; Bowen Liu; Ying Chen; Xingping Quan; Yan Han; Ying Zheng; Yonghua Zhao (Translational Stroke Research, 2022)

Susceptibility of patients with chronic obstructive pulmonary disease to heart rate difference associated with the short-term exposure to metals in ambient fine particles: A panel study in Beijing, China - Ke Gao; Xi Chen; Xiaoying Li; Hanxiyue Zhang; Mengxiao Luan; Yuan Yao; Yifan Xu; Teng Wang; Yiqun Han; Tao Xue; Junxia Wang; Mei Zheng; et al. (Science China Life Sciences, 2022)

Geochronology and geochemistry of Early Cretaceous bimodal volcanic rocks from Erguna Massif, NE China: evidence for the back-arc extension of the Mongol–Okhotsk orogenic belt - Fei Yang; Gong-Zheng Chen; Guang Wu; Ying-Lei Li; Yong-Xu Shao; Tie-Gang Li; Guang-Chao Song; Bing Han (International Journal of Earth Sciences, 2022)

Identification and bioinformatics analysis of differentially expressed milk exosomal microRNAs in milk exosomes of heat-stressed Holstein cows - Yue Wang; Jian Fang; Han-Fang Zeng; Ji-Feng Zhong; Hui-Xia Li; Kun-Lin Chen (Functional & Integrative Genomics, 2022)

Individual exposure to ambient PM2.5 and hospital admissions for COPD in 110 hospitals: a case-crossover study in Guangzhou, China - Jie-Qi Jin; Dong Han; Qi Tian; Zhao-Yue Chen; Yun-Shao Ye; Qiao-Xuan Lin; Chun-Quan Ou; Li Li (Environmental Science and Pollution Research, 2022)
Few studies have evaluated the short-term association between hospital admissions and individual exposure to ambient particulate matter (PM 2.5 ). Particularly, no studies focused on hospital admissions for chronic obstructive pulmonary disease (COPD) at the individual level. We assessed the short-term effects of PM 2.5 on hospitalization admissions for COPD in Guangzhou, China, during 2014–2015, based on satellite-derived estimates of ambient PM 2.5 concentrations at a 1-km resolution near the residential address as individual-level exposure for each patient. Around 40,002 patients with COPD admitted to 110 hospitals were included in this study. A time-stratified case-crossover design with conditional logistic regression models was applied to assess the effects of PM 2.5 based on a 1-km grid data of aerosol optical depth provided by the National Aeronautics and Space Administration on hospital admissions for COPD. Further, we performed stratified analyses by individual demographic characteristics and season of hospital admission. Around 10 μg/m 3 increase in individual-level PM 2.5 was associated with an increase of 1.6% (95% confidence interval [CI]: 0.6%, 2.7%) in hospitalization for COPD at a lag of 0–5 days. The impact of PM 2.5 on hospitalization for COPD was greater significantly in males and patients admitted in summer. Our study strengthened the evidence for the adverse effect of PM 2.5 based on satellite-based individual-level exposure data.

Does the institutional environment influence corporate social responsibility? Consideration of green investment of enterprises—evidence from China - Shu-Rong Han; Pei Li; Jian-Jun Xiang; Xiang-Hua Luo; Chun-Yan Chen (Environmental Science and Pollution Research, 2022)

Advenella mandrilli sp. nov., a bacterium isolated from the faeces of Mandrillus sphinx - Qiong Wang; Xiu-Lin Han; Zhi-Qin Fang; Chen-Lu Zhang; Chun Li; Tao Lu (Antonie van Leeuwenhoek, 2022)

Development and validation of a 30-day death nomogram in patients with spontaneous cerebral hemorrhage: a retrospective cohort study - Qian Han; Mei Li; Dongpo Su; Aijun Fu; Lin Li; Tong Chen (Acta Neurologica Belgica, 2022)

Otolith Microchemistry and Demographic History Provide New Insight into the Migratory Behavior and Heterogeneous Genetic Divergence of Coilia grayii in the Pearl River - Gongpei Wang; Qindong Tang; Zhi Chen; Dingli Guo; Lei Zhou; Han Lai; Guifeng Li (Fishes, 2022)
Coilia grayii is the anadromous form of anchovy that is distributed in the East and South China Seas. It is a common fish species in the estuarine area of the Pearl River. Nevertheless, freshwater populations appear upstream in the Pearl River, but the migratory pathway has been mostly impeded by dam construction. Behavioral differences and constrained habitat within tributaries are suspected of promoting genetic divergence in these populations. In this study, we investigated the migratory behavior and genetic divergence of six populations of C. grayii fragmented by dams based on the otolith strontium/calcium (Sr/Ca) ratio, mitochondrial DNA, and microsatellite genotyping. All populations were in freshwater with low Sr/Ca ratios, except the estuarine population (Humen population) hatched in brackish water. Reduced nucleotide diversity corresponding to distance was observed. Populations from distant hydrological regions exhibited a decline in genetic diversity and a significant difference with the remaining populations after fitting the isolation by distance model. Pairwise fixation indices confirmed these results and moderate and significant differentiation was found between Hengxian site and downstream sites. Furthermore, STRUCTURE analyses revealed that all separated populations exhibited an admixed phylogenetic pattern except for individuals from the Hengxian locality. The upstream sites showed significantly increased resistance to gene flow from the estuarine population because of isolation by the dam. The results of the neutrality test and Bayesian skyline plots demonstrated complex demography—individuals’ experienced historical expansion and partial upper-dam populations had recently undergone a colonization, forming a new genetic structure. Accordingly, this study demonstrates differences in the migration pattern and genetic differentiation of C. grayii as a consequence of demographic history and current processes (habitat fragmentation and colonization).

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Assembly of rhizosphere microbial communities in Artemisia annua: recruitment of plant growth‐promoting microorganisms and inter‐kingdom interactions between bacteria and fungi - Yuhua Shi; Yanshuo Pan; Li Xiang; Zhihui Zhu; Wenbo Fu; Guangfei Hao; Zengchao Geng; Shilin Chen; Yuzhong Li; Dongfei Han (Plant and Soil, 2022)

Near-epicenter weather conditions several hours before strong earthquakes (Ms ≥ 6) - Tao Chen; Lei Li; Xiao-Xin Zhang; Qi-Ming Ma; Wen Li; Shuo Ti; Han Wu; Ren-Kang Li; Jing Luo; Jian-Feng Su (Natural Hazards, 2022)

Comparative transcriptomic analysis of Macrobrachium nipponense in response to Aeromonas veronii or Staphylococcus aureus infection - Chong Han; Zhipeng Zhang; Qiang Li; Qinghua Chen; Jianrong Huang (Journal of Oceanology and Limnology, 2022)

Bottomside ionospheric snapshot modeling using the LEO navigation augmentation signal from the Luojia-1A satellite - Tao Li; Lei Wang; Wenju Fu; Yi Han; Haitao Zhou; Ruizhi Chen (GPS Solutions, 2022)

Simulating the impact of highway construction to landslides with creep deformation using DDA: a case study of Qinglong landslide in Guizhou Province, China - Jiaying Li; Weidong Wang; Guangqi Chen; Zheng Han (Arabian Journal of Geosciences, 2022)

Effects of different compaction methods on the performance of reinforced earth retaining wall - Lihua Li; Chengbin Fan; Han Yan; Hang Li; Xinlong Zhou; Na Chen; Jie Huang; Zhi Chen (Arabian Journal of Geosciences, 2022)

Geochemical characteristics and origin of Chang-9 crude oil of Triassic Yanchang Formation in Zhidan area, Ordos Basin, China - Zhengyu Wu; Shijia Chen; Chengshan Li; Jian Yu; Yibo Chang; Zixing Lu; Xin He; Haifeng Zhang; Han Meimei (Arabian Journal of Geosciences, 2022)

Geochemistry and Sr–Nd isotopes of the Late Mesozoic lamprophyres in the Chaohu area, eastern China : Petrogenesis and tectonic implications - Mo Chen; Longming Li; Tianxiang Kan; Hang Liu; Xilin Zhao; Jiahao Li; Xu Han (Island Arc, 2022)
Late Mesozoic lamprophyres are widespread in the Chaohu area of the Lower Yangtze region, eastern China. These mantle‐derived rocks are of great significance for understanding the characteristics of mantle source and tectonic environment of eastern China during the Late Mesozoic. The lamprophyres from the Chaohu area can be divided into two types. The type‐I lamprophyres have low SiO 2 (43.8–44.5 wt.%) and TiO 2 (1.06–1.14 wt.%), high MgO (13.5–17.5 wt.%) and high contents of compatible elements, and are enriched in LREE and LILE but depleted in HFSE. They have high initial 87 Sr/ 86 Sr (0.70767–0.70904) and negative εNd ( t ) (−4.8 to −4.4). The type‐II lamprophyres are characterized by low contents of SiO 2 (43.0–45.4 wt.%), high TiO 2 (1.74–2.55 wt.%), MgO (9.17–15.4 wt.%), and compatible elements. They are also enriched in LREE and LILE but depleted in HFSE. They show enriched Sr‐Nd isotopic compositions with initial 87 Sr/ 86 Sr values (0.70773–0.70886) and εNd ( t ) values (−8.6 to −7.8). The type‐I lamprophyres show higher Mg # and MgO contents but significant lower TiO 2 than the type‐II lamprophyres. In addition, the type‐I lamprophyres have relatively similar initial 87 Sr/ 86 Sr ratios but higher εNd( t ) values than the type‐II lamprophyres. The difference of geochemical characteristics between the type‐I and type‐II lamprophyres may be caused by different degrees of partial melting of an amphibole‐bearing garnet lherzolite mantle. The lithospheric mantle was metasomatised by the fluids caused by the rollback of the Paleo‐Pacific plate subduction during the Late Cretaceous.

Biodiversity alleviates the decrease of grassland multifunctionality under grazing disturbance: A global meta‐analysis - Ruiyang Zhang; Dashuan Tian; Han Y. H. Chen; Eric W. Seabloom; Guodong Han; Shaopeng Wang; Guirui Yu; Zhaolei Li; Shuli Niu (Global Ecology and Biogeography, 2022)
Aim Biodiversity drives the delivery of multiple ecosystem functions related to carbon and nutrient cycling (ecosystem multifunctionality, EMF), and biodiversity and ecosystem functioning are strongly threatened by intensive grazing in grasslands. However, it remains unclear how biodiversity regulates EMF changes in response to intensive grazing. Location Global. Time period From 1992 to 2018. Major taxa studied Grassland. Methods Here, we conducted a global synthesis using 373 paired observations from 90 published studies to address the responses of plant diversity, EMF and their relationships to grazing disturbance depending on grazing intensity, livestock type, grazing duration, and climatic aridity. Results Our results showed that EMF significantly decreased with increasing grazing intensity, but the negative EMF response was alleviated at high levels of plant diversity. The grazing‐induced changes in EMF increased linearly with the changes in plant diversity, with the slopes increasing by 78.9% from light to heavy grazing. In addition, the grazing‐induced decrease of EMF was stronger with longer grazing duration and more arid climates. Structural equation models suggested that grazing intensity reduced EMF largely via decreasing plant diversity, whereas upsizing livestock type promoted EMF by increasing plant diversity. Main conclusions This study highlights the key role of biodiversity in mediating EMF in response to intensifying grazing disturbance. We call for conservation of biodiversity to maintain grassland multifunctionality and services.

An accurate and robust registration framework based on outlier removal and feature point adjustment for remote sensing images - Han Yang; Xiaorun Li; Liaoying Zhao; Shuhan Chen (International Journal of Remote Sensing, 2021)

The decreased expression of GW2 homologous genes contributed to the increased grain width and thousand‑grain weight in wheat-Dasypyrum villosum 6VS·6DL translocation lines - Zhiyu Feng; Long Song; Wanjun Song; Zhongqi Qi; Jun Yuan; Run Li; Haiming Han; Huifang Wang; Zhaoyan Chen; Weilong Guo; Mingming Xin; Jie Liu; et al. (Theoretical and Applied Genetics, 2021)

Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum–Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats - Kokwin Ooi; Li Hu; Yi Feng; Chenzhi Han; Xiaorong Ren; Xinyi Qian; Haofeng Huang; Sijia Chen; Qi Shi; Hong Lin; Jijiang Wang; Danian Zhu; et al. (Molecular Neurobiology, 2021)

Osteoarthritic infrapatellar fat pad aggravates cartilage degradation via activation of p38MAPK and ERK1/2 pathways - Zuoqing Zhou; Su’an Tang; Xiaoyu Nie; Yiqun Zhang; Delong Li; Yang Zhao; Yumei Cao; Jianwen Yin; Tianyu Chen; Guangfeng Ruan; Zhaohua Zhu; Xiaochun Bai; et al. (Inflammation Research, 2021)

Environmental contamination with SARS‐CoV ‐2 in COVID ‐19 hospitals in Wuhan, China, 2020 - Wei Liu; Dingchen Li; Chaojie Yang; Fangyan Chen; Ruizhong Jia; Leili Jia; Xinyi Xia; Shanhong Fan; Qing Tan; Yuehua Ke; Yong Chen; Haifeng Li; et al. (Environmental Microbiology, 2021)
Summary Coronavirus disease 2019 (COVID‐19) pandemic has caused high number of infections and deaths of healthcare workers globally. Distribution and possible transmission route of SARS‐CoV‐2 in hospital environment should be clarified. We herein collected 431 environmental (391 surface and 40 air) samples in the intensive care unit (ICU) and general wards (GWs) of three hospitals in Wuhan, China from February 21 to March 4, 2020, and detected SARS‐CoV‐2 RNA by real‐time quantitative PCR. The viral positive rate in the contaminated areas was 17.8% (28/157), whereas there was no virus detected in the clean areas. Higher positive rate (22/59, 37.3%) was found in ICU than that in GWs (3/63, 4.8%). The surfaces of computer keyboards and mouse in the ICU were the most contaminated (8/10, 80.0%), followed by the ground (6/9, 66.7%) and outer glove (2/5, 40.0%). From 17 air samples in the contaminated areas, only one sample collected at a distance of around 30 cm from the patient was positive. Enhanced surface disinfection and hand hygiene effectively decontaminated the virus from the environment. This finding might help understand the transmission route and contamination risk of SARS‐CoV‐2 and evaluate the effectiveness of infection prevention and control measures in healthcare facilities.

Development and Research Status of Tidal Current Power Generation Systems in China - Hao Chen; Qi Li; Mohamed Benbouzid; Jingang Han; Nadia Aït-Ahmed (Journal of Marine Science and Engineering, 2021)
Considering the depletion of oil, coal, gas and other fossil energy, and the increasingly serious environmental pollution, all countries in the world are developing clean and renewable energy, such as wind energy, water energy, solar energy, etc., to alleviate the current energy crisis. Tidal current energy belongs to the marine renewable energy. It is clean, pollution-free, and abundant, with a good prospect of development due to its similarity with wind energy. This paper firstly analyses the reserves and distribution of tidal current energy in China. Then the early exploration of Tidal Current Power Generation System (TCPGS) in China is briefly introduced. Subsequently, it gives the details of the devices and experimental platforms of TCPGS that were researched and developed by various universities, research institutes and enterprises in China. The information mainly includes: the size and the capacity of the system, the support structure, turbine type, the selection of generator, and some river and offshore test information, etc. Finally, it discusses the similarities and differences between China and other countries in tidal current power generation technology, and summaries the current development status and gives the prospect of the TCPGS technology in China.

Three new diterpenoids from Euphorbia peplus - Yan-Ni Chen; Qing-Yun Lu; Dong-Mei Li; Ying-Yao Li; Xue-Xue Pu; Bo-Ting Li; Xiao-Han Tang; Hong-Yu Tang; Shuai Liu; Lei Yang; Yu Zhang; Ying-Tong Di; et al. (Natural Product Research, 2021)

GhWRKY21 regulates ABA-mediated drought tolerance by fine-tuning the expression of GhHAB in cotton - Jiayu Wang; Lijun Wang; Yan Yan; Shuxin Zhang; Han Li; Zheng Gao; Chen Wang; Xingqi Guo (Plant Cell Reports, 2021)

Lipin1 Alleviates Autophagy Disorder in Sciatic Nerve and Improves Diabetic Peripheral Neuropathy - Meijian Wang; Min Xie; Shuyan Yu; Pan Shang; Cong Zhang; Xiaolin Han; Cuiqin Fan; Li Chen; Xianghua Zhuang; Shihong Chen (Molecular Neurobiology, 2021)

Spatiotemporal analysis and potential impact factors of vegetation variation in the karst region of Southwest China - Wei Chen; Shuang Bai; Haimeng Zhao; Xuerong Han; Lihe Li (Environmental Science and Pollution Research, 2021)

A comprehensive exploration on pollution characteristics and health risks of potentially toxic elements in indoor dust from a large Cu smelting area, Central China - Han-Zhi Wang; Li-Mei Cai; Shuo Wang; Guo-Cheng Hu; Lai-Guo Chen (Environmental Science and Pollution Research, 2021)

High-throughput sequencing revealed the expression profile and potential key molecules of the circular RNAs involved in the process of hypoxic adaptation in Tibetan chickens - Zengrong Zhang; Mohan Qiu; Huarui Du; Qingyun Li; Wu Gan; Xia Xiong; Chunlin Yu; Han Peng; Bo Xia; Xiaoyan Song; Li Yang; Chenming Hu; et al. (Biologia, 2021)

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Social disruption–induced stress pre-exposure aggravates, while the presence of conspecifics diminishes, acetic acid–induced writhing - Yi-Han Liao; Yi-Chi Su; Yu-Han Huang; Hao Chen; Ya-Hsuan Chan; Li-Han Sun; Chianfang G. Cherng; Ing-Tiau B. Kuo; Lung Yu (Psychopharmacology, 2021)

Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice - Lin Chen; Shu-Yu Ren; Rui-Xue Li; Kun Liu; Jing-Fei Chen; Yu-Jian Yang; Yong-Bin Deng; Han-Zhi Wang; Lan Xiao; Feng Mei; Fei Wang (Neuroscience Bulletin, 2021)
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths ( NG2-CreER TM ; Tau-mGFP ), we found that myelinogenesis was highly active in most brain regions, such as the motor cortex and corpus callosum. After exposure to hypoxia (10% oxygen) 12 h per day for 4 weeks, myelinogenesis was largely inhibited in the 4-month old brain and the mice displayed motor coordination deficits revealed by the beam-walking test. To determine the relationship between the inhibited myelination and functional impairment, we induced oligodendroglia-specific deletion of the transcription factor Olig2 by tamoxifen ( NG2-CreER TM ; Tau-mGFP; Olig2 fl/fl ) in adult mice to mimic the decreased myelinogenesis caused by hypoxia. The deletion of Olig2 inhibited myelinogenesis and consequently impaired motor coordination, suggesting that myelinogenesis is required for motor function in adult mice. To understand whether enhancing myelination could protect brain functions against hypoxia, we treated hypoxic mice with the myelination-enhancing drug-clemastine, which resulted in enhanced myelogenesis and improved motor coordination. Taken together, our data indicate that chronic hypoxia inhibits myelinogenesis and causes functional deficits in the brain and that enhancing myelinogenesis protects brain functions against hypoxia-related deficits.

A network pharmacology study with molecular docking to investigate the possibility of licorice against posttraumatic stress disorder - Zhi-Kun Qiu; Zhi-Ting Liu; Jia-Li Pang; Han-Biao Wu; Xu Liu; Ze-Min Yang; Xiong Li; Ji-Sheng Chen (Metabolic Brain Disease, 2021)

Regional brain network and behavioral alterations in EGR3 gene transfected rat model of schizophrenia - Wenwen Gao; Guangfei Li; Xiaowei Han; Zeyu Song; Shuai Zhao; Feiyi Sun; Hong Ma; Ailing Cui; Yige Wang; Xiuxiu Liu; Yue Chen; Lu Zhang; et al. (Brain Imaging and Behavior, 2021)

Effects on the STAT3-shRNA in Non-Small-Cell Lung Cancer Therapy: Design, Induction of Apoptosis, and Conjugation with Chitosan-Based Gene Vectors - Wangwang Zhang; Yan Zhang; Zhiwen Jiang; Le Sun; Litong Wang; Zhiyang Gu; Wenya Li; Lili Guo; Xiaotong Chen; Haibin Zhang; Baoqin Han; Jing Chang (Journal of Ocean University of China, 2021)

Raspberry (Rubus idaeus L.) NCED1 gene enhances high salinity and cold tolerance in Arabidopsis - Guohui Yang; Yuxiao Chen; Heng Yu; Hang Zhang; Deguo Han; Xiaoyu Guo; Enqing Yan; Hanyi Quan; Tiemei Li (In Vitro Cellular & Developmental Biology - Plant, 2021)

Highly sialylated mucin-type glycopeptide from porcine intestinal mucosa after heparin extraction: O-glycan profiling and immunological activity evaluation - Xin Zhang; Chen Wang; Qing Han; Xuan Chen; Guoyun Li; Guangli Yu (Glycoconjugate Journal, 2021)

Enhanced antitumor activity of inulin-capped Se nanoparticles synthesized using Jerusalem artichoke tubers - Taili Shao; Wei Liu; Pingchuan Yuan; Xichen Li; Honggang Xu; Chunyan Liu; Kaoshan Chen; Lihua Li; Jun Han; Guodong Wang (Glycoconjugate Journal, 2021)

Optimization of oil source correlation indexes: a case of Chang 10 member in Ordos Basin’ Zhoujiawan area - Kun Xu; Shijia Chen; Yuting Hou; Zixing Lu; Chen Li; Meimei Han (Arabian Journal of Geosciences, 2021)

Sesquiterpenoids from Artemisia argyi and their NO production inhibitory activity in RAW264.7 cells - Gui-Min Xue; Jin-Feng Xue; Chen-Guang Zhao; Zhen-Zhu Zhao; Yan-Jun Sun; Kun Du; Han-Wei Li; Wei-Sheng Feng (Natural Product Research, 2021)

The advances of topology optimization techniques in orthopedic implants: A review - Naichao Wu; Shan Li; Boyan Zhang; Chenyu Wang; Bingpeng Chen; Qing Han; Jincheng Wang (Medical & Biological Engineering & Computing, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

Precipitation manipulation and terrestrial carbon cycling: The roles of treatment magnitude, experimental duration and local climate - Jinsong Wang; Dashuan Tian; Alan K. Knapp; Han Y. H. Chen; Yiqi Luo; Zhaolei Li; Enqing Hou; Xinzhao Huang; Lifen Jiang; Shuli Niu (Global Ecology and Biogeography, 2021)
Aim Precipitation manipulation experiments have shown diverse terrestrial carbon (C) cycling responses when the ecosystem is subjected to different magnitudes of altered precipitation, various experimental durations or heterogeneity in local climate. However, how these factors combine to affect C cycle responses to changes in precipitation remains unclear. Location Global. Time period 1990–2019. Major taxa studied Terrestrial ecosystems. Methods Using observations from 230 published studies in which precipitation was manipulated and terrestrial C cycling variables were measured, we conducted a global meta‐analysis to investigate responses of diverse C cycle processes to altered precipitation, including gross ecosystem productivity, ecosystem respiration, net ecosystem productivity, ecosystem carbon use efficiency, net primary productivity (NPP), aboveground and belowground NPP, aboveground and belowground biomass, shoot‐to‐root ratio, soil respiration and soil microbial biomass C. Results We found that C cycling responses were correlated linearly and positively with the magnitude of precipitation treatments. We also detected that the responses of NPP and its aboveground component (ANPP) to altered precipitation weakened with experimental duration. Furthermore, gross ecosystem productivity, ecosystem respiration and net ecosystem productivity showed larger responses to precipitation treatments of greater magnitude over shorter time periods. The response of soil respiration, a key component of the C budget in most terrestrial ecosystems, depended in particular on the local climate. Local temperature and precipitation not only influenced the magnitude of the response of soil respiration to altered precipitation but also affected its sensitivity to the magnitude of the precipitation treatments, with higher sensitivities in the response of soil respiration to treatment magnitude at drier and colder sites. Main conclusions Our findings highlight the importance of the interactions between the magnitude of precipitation treatments, their duration and the local climate in the response of ecosystem C cycling to altered precipitation, which is crucial to a better understanding of ecosystem C processes and functioning and projecting them under changing precipitation regimes.

Pinocembrin-7-Methylether Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity via Modulating Nrf2 Induction Through AKT and ERK Pathways - Zhi-Cong Zou; Ji-Jun Fu; Yuan-Ye Dang; Qian Zhang; Xiu-Fen Wang; Han-Bin Chen; Xue-Jing Jia; Simon Ming-Yuen Lee; Chu-Wen Li (Neurotoxicity Research, 2021)

Ferroptosis is involved in the development of neuropathic pain and allodynia - Huixing Wang; Xiaodong Huo; Chenyang Han; Jiang Ning; Hongguang Chen; Bo Li; Jingzhi Liu; Wenting Ma; Quanbo Li; Yonghao Yu; Kemei Shi (Molecular and Cellular Biochemistry, 2021)

Overexpression of Cell-Surface Marker SLC16A1 Shortened Survival in Human High-Grade Gliomas - Hong-Han Lin; Wen-Chiuan Tsai; Chia-Kuang Tsai; Ssu-Han Chen; Li-Chun Huang; Dueng-Yuan Hueng; Kuang-Chen Hung (Journal of Molecular Neuroscience, 2021)

Effects of dietary whole and defatted Arthrospira platensis (Cyanobacterium) on growth, body composition and pigmentation of the yellow catfish Pelteobagrus fulvidraco - Cui Liu; Yanhua Li; Zheng Chen; Li Yuan; Haokun Liu; Dong Han; Junyan Jin; Yunxia Yang; Qiang Hu; Xiaoming Zhu; Shouqi Xie (Journal of Applied Phycology, 2021)

Comparison of clinical characteristics and outcomes between respiratory syncytial virus and influenza-related pneumonia in China from 2013 to 2019 - Liang Chen; Xiudi Han; YanLi Li; Chunxiao Zhang; Xiqian Xing (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Antimicrobial nanomedicine for ocular bacterial and fungal infection - Wenjie Fan; Haijie Han; Yaoyao Chen; Xiaobo Zhang; Yifan Gao; Su Li; Qiao Jin; Jian Ji; Ke Yao (Drug Delivery and Translational Research, 2021)

Frequency-specific altered global signal topography in drug-naïve first-episode patients with adolescent-onset schizophrenia - Xiao Wang; Wei Liao; Shaoqiang Han; Jiao Li; Yifeng Wang; Yan Zhang; Jingping Zhao; Huafu Chen (Brain Imaging and Behavior, 2021)

Safety evaluation and failure behavior of degraded tunnel structure with compound diseases of voids and lining defects - Wei Han; Yujing Jiang; Ningbo Li; Dairiku Koga; Osamu Sakaguchi; Hongbin Chen (Arabian Journal of Geosciences, 2021)

Characteristics of RNA alternative splicing and its potential roles in ginsenoside biosynthesis in a single plant of ginseng, Panax ginseng C.A. Meyer - Yilai Han; Lei Zhu; Li Li; Yanfang Wang; Mingzhu Zhao; Kangyu Wang; Chunyu Sun; Jing Chen; Lingyu Liu; Ping Chen; Jun Lei; Yi Wang; et al. (Molecular Genetics and Genomics, 2021)

Green-synthesized nanosize Mont-supported Fe0 via tea extract for enhanced transport and in situ remediation of Pb(II) in soil - Han Yang; Zhi Ye; Fang Feng; Nan Xu; Jing Yang; Zihan Yao; Zuling Li; Jianping Chen (Journal of Soils and Sediments, 2021)

Archaeal and bacterial community structures of rural household biogas digesters with different raw materials in Qinghai Plateau - Rui Han; Li Liu; Yan Meng; Hairong Han; Rongbo Xiong; Yi Li; Laisheng Chen (Biotechnology Letters, 2021)

Distributions of Total Mercury and Methylmercury in Dragonflies from a Large, Abandoned Mercury Mining Region in China - Gaoen Wu; Shunlin Tang; Jialiang Han; Chan Li; Lin Liu; Xiaohang Xu; Zhidong Xu; Zhuo Chen; Yajie Wang; Guangle Qiu (Archives of Environmental Contamination and Toxicology, 2021)

Proteome landscape and spatial map of mouse primordial germ cells - Pan Wang; Yilong Miao; Xiao-Han Li; Na Zhang; Qilong Wang; Wei Yue; Shao-Chen Sun; Bo Xiong; Jie Qiao; Mo Li (Science China Life Sciences, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment - Rui-Yuan Zhang; Jie-Bai Tu; Rui-Tu Ran; Wen-Xuan Zhang; Qiang Tan; Ping Tang; Tao Kuang; Shu-Qun Cheng; Cheng-Zhi Chen; Xue-Jun Jiang; Chang Chen; Ting-Li Han; et al. (Neurotoxicity Research, 2021)

Phthalate exposure in association with the use of personal care products among general population from Shanghai - Jin Qin; Ruihua Dong; Min Wu; Yaqun Yuan; Han Zhang; Pai Meng; Meiru Zhang; Jingsi Chen; Shuguang Li; Bo Chen (Environmental Science and Pollution Research, 2021)

Exploring the long-term vegetation dynamics of different ecological zones in the farming-pastoral ecotone in northern China - Wei Chen; Aijia Li; Yungang Hu; Lihe Li; Haimeng Zhao; Xuerong Han; Bin Yang (Environmental Science and Pollution Research, 2021)

Pigment profile and gene analysis revealed the reasons of petal color difference of crabapples - Ting Shen; Meiling Han; Qianrui Liu; Chen Yang; Jiaxin Meng; Houhua Li (Brazilian Journal of Botany, 2021)

Disrupted pathways from frontal-parietal cortex to basal ganglia and cerebellum in patients with unmedicated obsessive compulsive disorder as observed by whole-brain resting-state effective connectivity analysis – a small sample pilot study - Wei Liu; Minghui Hua; Jun Qin; Qiuju Tang; Yunyi Han; Hongjun Tian; Daxiang Lian; Zhengqing Zhang; Wenqiang Wang; Chunxiang Wang; Ce Chen; Deguo Jiang; et al. (Brain Imaging and Behavior, 2021)

Paleoclimatic proxies from global closed basins and the possible beginning of Anthropocene - Yu Li; Qin Han; Lu Hao; Xinzhong Zhang; Dawei Chen; Yuxin Zhang; Lingmei Xu; Wangting Ye; Simin Peng; Yichan Li; Zhuowen Feng; Hebin Liu (Journal of Geographical Sciences, 2021)

Greater toxic potency of bisphenol AF than bisphenol A in growth, reproduction, and transcription of genes in Daphnia magna - Sheng Chen; Xiaodong Li; Han Li; Siliang Yuan; Jun Li; Chunsheng Liu (Environmental Science and Pollution Research, 2021)

Spatiotemporal characteristics of nitrogen dioxide pollution in mainland China from 2015 to 2018 - Xinglin Chen; Xiulan Han; Junming Li (Environmental Monitoring and Assessment, 2021)

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

The circular RNA circSlc7a11 promotes bone cancer pain pathogenesis in rats by modulating LLC-WRC 256 cell proliferation and apoptosis - Han-Wen Chen; Xiao-Xia Zhang; Zhu-Ding Peng; Zu-Min Xing; Yi-Wen Zhang; Ya-Lan Li (Molecular and Cellular Biochemistry, 2021)
Treatment of bone cancer pain (BCP) caused by bone metastasis in advanced cancers remains a challenge in clinical oncology, and the underlying mechanisms of BCP are poorly understood. This study aimed to investigate the pathogenic roles of circular RNAs (circRNAs) in regulating cancer cell proliferation and BCP development. Eight differentially expressed circRNAs in the rat spinal cord were validated by agarose gel electrophoresis and Sanger sequencing. Expression of circRNAs and mRNAs was detected by quantitative RT-PCR. MTS assay and flow cytometry were performed to analyze cell proliferation and apoptosis, respectively. Differentially expressed mRNA profiles were characterized by deep RNA sequencing, hierarchical clustering, and functional categorization. The interactions among circRNAs, microRNAs (miRNAs), and mRNAs were predicted using TargetScan. Additionally, western blot was performed to determine the protein levels of Pax8, Isg15, and Cxcl10. Multiple circRNAs were differentially expressed in the spinal cords of BCP model rats; of these, circSlc7a11 showed the greatest increase in expression. The overexpression of circSlc7a11 significantly promoted cell proliferation and repressed apoptosis of LLC-WRC 256 and UMR-106 cells, whereas circSlc7a11 silencing produced the opposite effects. Altered expression of circSlc7a11 also induced substantial changes in the mRNA expression profiles of LLC-WRC 256 cells; these changes were linked to multiple apoptotic processes and signaling pathways, such as the chemokine signaling pathway, and formed a complex circRNA/miRNA/mRNA network. Additionally, Pax8, Isg15, and Cxc110 protein level in LLC-WRC 256 cells was consistent with the mRNA results. The circRNA circSlc7a11 regulates rat BCP development by modulating LLC-WRC 256 cell proliferation and apoptosis through multiple-signaling mechanisms.

Over-expression of Fgf8 in cardiac neural crest cells leads to persistent truncus arteriosus - Aijuan Tian; Shangqi Wang; Haoru Wang; Nan Li; Han Liu; Hailing Zhou; Xiaoyan Chen; Xuena Liu; Jiamin Deng; Jing Xiao; Chao Liu (Journal of Molecular Histology, 2021)

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Greenhouse gas emissions from semi-aerobic bioreactor landfills with different vent-pipe diameters - Guobin Jiang; Dan Liu; Weiming Chen; Zhiyong Han; Qibin Li (Environmental Science and Pollution Research, 2021)

Numerical simulation and analysis of a geological disaster chain in the Peilong valley, SE Tibetan Plateau - Zhihai Li; Fujun Zhou; Xudong Han; Jianping Chen; Yuchao Li; Shijie Zhai; Mengxia Han; Yiding Bao (Bulletin of Engineering Geology and the Environment, 2021)

To the light side: molecular diversity and morphology of stomatopod larvae and juveniles (Crustacea: Malacostraca: Stomatopoda) from crustose coralline algal reefs in Taiwan - Kingsley J. H. Wong; Yao-Feng Tsao; Pei-Chen Tsai; Wei-Peng Hsieh; Han-Ru Li; Ryuji J. Machida; Benny K. K. Chan (Marine Biodiversity, 2021)

Comprehensive Marine Observing Experiment Based on High-Altitude Large Unmanned Aerial Vehicle (South China Sea Experiment 2020 of the “Petrel Project”) - Xuefen Zhang; Liangxu Li; Rongkang Yang; Ran Guo; Xia Sun; Jianping Luo; Hongbin Chen; Daxin Liu; Kebing Tang; Wenwu Peng; Xiaodong Han; Qiyun Guo; et al. (Advances in Atmospheric Sciences, 2021)

Adaptive T cell immunotherapy in cancer - Dongdong Ti; Miaomiao Bai; Xiaolei Li; Jianshu Wei; Deyun Chen; Zhiqiang Wu; Yao Wang; Weidong Han (Science China Life Sciences, 2021)

Unraveling Physiological and Metabolomic Responses Involved in Phlox subulata L. Tolerance to Drought Stress - Yan Xiong; Yanting Qu; Hui Han; Fei Chen; Li Li; Huanwei Tang; Daidi Che; Xing Zhang (Plant Molecular Biology Reporter, 2021)

The cellulose synthase (CesA) gene family in four Gossypium species: phylogenetics, sequence variation and gene expression in relation to fiber quality in Upland cotton - Sujun Zhang; Zhenxing Jiang; Jie Chen; Zongfu Han; Jina Chi; Xihua Li; Jiwen Yu; Chaozhu Xing; Mingzhou Song; Jianyong Wu; Feng Liu; Xiangyun Zhang; et al. (Molecular Genetics and Genomics, 2021)

Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling - Li Zhang; Lu Wang; Han Xiao; Hui Gan; Hui Chen; Shuyue Zheng; Dan Jian; Xuan Zhai; Ning Jiang; Zhao Jing; Ping Liang (Journal of Molecular Medicine, 2021)

Refining the empirical global pressure and temperature model with the ERA5 reanalysis and radiosonde data - Tao Li; Lei Wang; Ruizhi Chen; Wenju Fu; Beizhen Xu; Peng Jiang; Jian Liu; Haitao Zhou; Yi Han (Journal of Geodesy, 2021)

Enhanced antioxidant capacity and upregulated transporter genes contribute to the UV-B-induced increase in blinin in Conyza blinii - Junyi Zhan; Qin Yang; Zhiyi Lin; Tianrun Zheng; Maojia Wang; Wenjun Sun; Tongliang Bu; Zizhong Tang; Chenglei Li; Xueyi Han; Haixia Zhao; Qi Wu; et al. (Environmental Science and Pollution Research, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

MiR-3613-3p inhibits hypertrophic scar formation by down-regulating arginine and glutamate-rich 1 - Lisha Li; Weiqiang Han; Yun Chen; Yuhua Chen (Molecular and Cellular Biochemistry, 2021)

TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial–mesenchymal transition - Zhi-Han Li; Lei Lei; Liang-Ru Fei; Wen-Jing Huang; Yi-Wen Zheng; Mai-Qing Yang; Zhao Wang; Chen-Chen Liu; Hong-Tao Xu (Journal of Molecular Histology, 2021)

Timing of coseismic displacement grid model construction for updating the semi-kinematic reference frame: case study in Taiwan - Shih-Han Hsiao; Kuo-En Ching; Kwo-Hwa Chen; Chien-Kuan Li (Journal of Geodesy, 2021)

The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish - Si-Lan Han; Yan Liu; Samwel M. Limbu; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2021)

Wolbachia and Spiroplasma could influence bacterial communities of the spider mite Tetranychus truncatus - Kun Yang; Han Chen; Xiao-Li Bing; Xue Xia; Yu-Xi Zhu; Xiao-Yue Hong (Experimental and Applied Acarology, 2021)

Occurrence and distribution of microplastics on recreational beaches of Haichow Bay, China - Xiaowei Wu; Chongqing Zhong; Teng Wang; Xinqing Zou; Zheng Zang; Qunji Li; Han Chen (Environmental Science and Pollution Research, 2021)

Altered resting-state networks may explain the executive impairment in young health immigrants into high-altitude area - Xiaoming Chen; Jian Liu; Jiye Wang; Zhenlong Xin; Qian Zhang; Wenbin Zhang; Yibin Xi; Yuanqiang Zhu; Chen Li; Jiaming Li; Yuedong Han; Jie Liu; et al. (Brain Imaging and Behavior, 2021)

Cerebral microbleeds and their influence on cognitive impairment in Dialysis patients - Yujun Qian; Ke Zheng; Haiyun Wang; Hui You; Fei Han; Jun Ni; Bo Hou; Limeng Chen; Yicheng Zhu; Feng Feng; Xuemei Li (Brain Imaging and Behavior, 2021)

Quantitatively determine the dominant driving factors of the spatial—temporal changes of vegetation NPP in the Hengduan Mountain area during 2000–2015 - Shu-ting Chen; Bing Guo; Rui Zhang; Wen-qian Zang; Cui-xia Wei; Hong-wei Wu; Xiao Yang; Xiao-yan Zhen; Xing Li; Da-fu Zhang; Bao-min Han; Hai-ling Zhang (Journal of Mountain Science, 2021)

Climate Services for Water Resource Management in China: The Case Study of Danjiangkou Reservoir - Yujie Wang; Xiang Li; Song Liu; Zhenyu Han; Lianchun Song; Zongjian Ke; Keyao Chen (Journal of Meteorological Research, 2021)

Geological, Fluid Inclusion, H-O-S-Pb Isotope Constraints on the Genesis of the Erdaogou Gold Deposit, Liaoning Province - Fan Yang; Xuejiao Pang; Bin Li; Jingsheng Chen; Jilong Han; Miao Liu; Zhongzhu Yang; Yan Wang; Yi Shi (Journal of Earth Science, 2021)