Long-term changes in organic and inorganic phosphorus compounds as affected by long-term synthetic fertilisers and pig manure in arable soils - Xue Li; Qiuxiang Wen; Shiyu Zhang; Na Li; Jinfeng Yang; Joan Romanyà; Xiaori Han (Plant and Soil, 2022)

Climatic controls of Pinus pumila radial growth along an altitude gradient - Jingwen Yang; David J. Cooper; Xu Zhang; Wenqi Song; Zongshan Li; Yuandong Zhang; Huiying Zhao; Shijie Han; Xiaochun Wang (New Forests, 2022)

Optimizing nitrogen fertilizer application under reduced irrigation strategies for winter wheat of the north China plain - Ying Liu; Meikun Han; Xiaonan Zhou; Wei Li; Chenghang Du; Yitao Zhang; Yinghua Zhang; Zhencai Sun; Zhimin Wang (Irrigation Science, 2022)

OTNet: A CNN Method Based on Hierarchical Attention Maps for Grading Arteriosclerosis of Fundus Images with Small Samples - Hang Bai; Li Gao; Xiongwen Quan; Han Zhang; Shuo Gao; Chuanze Kang; Jiaqiang Qi (Interdisciplinary Sciences: Computational Life Sciences, 2022)

Study on Reasonable Coal Pillar Width of Gob-Side Roadway Excavating with Multi-Layer Hard Roof in Western Deep Mine - Changliang Han; Houqiang Yang; Nong Zhang; Xudong Li; Yitao Liu; Wentao Liu; Wei Yao (Geotechnical and Geological Engineering, 2022)

Neuroprotective effect of aldose reductase knockout in a mouse model of spinal cord injury involves NF-κB pathway - Fu-xin Han; Rui Zhang; Xin-xing Yang; Shan-bo Ma; Shi-jie Hu; Bing Li (Experimental Brain Research, 2022)

QTL mapping integrated with BSA-Seq analysis identifies a novel gene conferring resistance to brown planthopper from common wild rice (Oryza rufipogon Griff.) - Xuan Wang; Yue Han; Yue-xiong Zhang; Biao Deng; Bi-qiu Wu; Xin-ying Guo; Yu-fen Qin; Yao-yu Fang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Euphytica, 2022)

Study on the impact of comprehensive urbanization on urban civil building CO2 emissions in China - Rong Guo; Nan Li; Hailin Mu; Ming Zhang; Xiyue Yang; Yixuan Han; Rongkang Yao; Zhihao Shao (Environmental Science and Pollution Research, 2022)

Polycyclic aromatic hydrocarbons in street dust from different functional areas in Chengdu, China: seasonal variation and health risk assessment - Han-Han Li; Zhan-Biao Yang; Xiao-Xun Xu; Xue-Mei Zhu; Jun-Ren Xian; Yuan-Xiang Yang; Zhang Cheng (Environmental Geochemistry and Health, 2022)

Environmental regulations and enterprises innovation performance: the role of R&D investments and political connections - Jintao Zhang; Zhen Yang; Li Meng; Lu Han (Environment, Development and Sustainability, 2022)

Spatial–temporal evolution pattern and prediction analysis of flood disasters in China in recent 500 years - Cuixia Wei; Bing Guo; Hailing Zhang; Baomin Han; Xiangshen Li; Huihui Zhao; Yuefeng Lu; Chao Meng; Xiangzhi Huang; Wenqian Zang; Hongwei Wu (Earth Science Informatics, 2022)

Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components - Tingting Lin; Jiaqi Tao; Ying Chen; Yitong Zhang; Fenglan Li; Yutong Zhang; Xueqing Han; Zihui Zhao; Guiyan Liu; Hui Li (Biological Trace Element Research, 2022)

Exosomal miRNA-328-3p targets ZO-3 and inhibits porcine epidemic diarrhea virus proliferation - Han Zhao; Jinxin Yang; Qian Wang; Zhanding Cui; Dengliang Li; Jiangting Niu; Yanbing Guo; Qian Zhang; Shuang Zhang; Yanli Zhao; Kai Wang; Wei Lian; et al. (Archives of Virology, 2022)

Susceptibility of patients with chronic obstructive pulmonary disease to heart rate difference associated with the short-term exposure to metals in ambient fine particles: A panel study in Beijing, China - Ke Gao; Xi Chen; Xiaoying Li; Hanxiyue Zhang; Mengxiao Luan; Yuan Yao; Yifan Xu; Teng Wang; Yiqun Han; Tao Xue; Junxia Wang; Mei Zheng; et al. (Science China Life Sciences, 2022)

Shifting from homogeneous to heterogeneous surfaces in estimating terrestrial evapotranspiration: Review and perspectives - Yuanbo Liu; Guoyu Qiu; Hongsheng Zhang; Yonghui Yang; Yinsheng Zhang; Quan Wang; Wenzhi Zhao; Li Jia; Xibin Ji; Yujiu Xiong; Chunhua Yan; Ning Ma; et al. (Science China Earth Sciences, 2022)

MicroRNA-451a attenuates angiotensin II–induced cardiac fibrosis and inflammation by directly targeting T-box1 - Hao-Yuan Deng; Ze-Yin He; Zhi-Chao Dong; Yun-Long Zhang; Xiao Han; Hui-Hua Li (Journal of Physiology and Biochemistry, 2022)

Identification and characterization of microRNAs involved in double-color formation in Paeonia suffruticosa ‘Shima Nishiki’ by high-throughput sequencing - Xinpeng Zhang; Jinshan Jia; Mingyuan Zhao; Cheng Li; Xu Han; Zongda Xu (Horticulture, Environment, and Biotechnology, 2022)

MiR-582-3p participates in the regulation of biological behaviors of A549 cells by ambient PM2.5 exposure - Mei Yang; Liangliang Ju; Changlian Li; Han Cheng; Na Li; Qi Zhang; Shu Sun; Liu Ding; Xinmiao Sui; Chao Zhang; Mingwei Yang; Jiyu Cao; et al. (Environmental Science and Pollution Research, 2022)

Association Between Essential Metal Elements and the Risk of Autism in Chinese Han Population - Jiahui Ma; Jing Wu; Haibin Li; Jingyu Wang; Jisheng Han; Rong Zhang (Biological Trace Element Research, 2022)

GATA4 Is a Transcriptional Regulator of SOX2 in Japanese Flounder (Paralichthys olivaceus) - Xiumei Liu; Zan Li; Weijie Yan; Haitao Zhao; Yuxiang Liu; Miao Han; Xubo Wang; Yan He; Haiyang Yu; Quanqi Zhang (Journal of Ocean University of China, 2022)

Developing a highly efficient regeneration system for leaves of tissue-cultured tetraploid Robinia pseudoacacia L. - Xiuyu Li; Qi Guo; Chao Han; Juan Li; Li Dong; Sen Cao; Zijie Zhang; Yuhan Sun; Ruohan Wang; Yun Li (In Vitro Cellular & Developmental Biology - Plant, 2022)

Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout - Ya-Wei Geng; Zhen Zhang; Han Jin; Jun-Long Da; Kai Zhang; Jian-Qun Wang; Yu-Yao Guo; Bin Zhang; Ying Li (Genes & Genomics, 2022)

Microbacterium sulfonylureivorans sp. nov., isolated from sulfonylurea herbicides degrading consortium - Qingyun Ma; Delong Kong; Qi Zhang; Miaomiao Li; Xiaoyan Han; Juan Che; Yiqing Zhou; Wei Zhang; Xu Jiang; Zhiyong Ruan (Archives of Microbiology, 2022)

Advenella mandrilli sp. nov., a bacterium isolated from the faeces of Mandrillus sphinx - Qiong Wang; Xiu-Lin Han; Zhi-Qin Fang; Chen-Lu Zhang; Chun Li; Tao Lu (Antonie van Leeuwenhoek, 2022)

Effect of tree form on wheat yield via changing microenvironment in almond–wheat intercropping - Wen Zhang; Hui Xie; Shou-An Han; Min Wang; Ming-Qi Pan; Xu Qiao; Long Li (Agroforestry Systems, 2022)

Two new nor -lignans from Selaginella pulvinata (Hook. & Grev.) Maxim and their antihyperglycemic activities - Hua-Wei Lv; Yu-Xia Li; Meng Luo; Jia-Meng Qi; Ze-Fei Fu; Hong-Jian Zhang; Yuan-Qiang Guo; Chu Chu; Han-Bing Li; Ji-Zhong Yan (Natural Product Research, 2022)

Applicability and improvement of different evapotranspiration methods of reference crops in Jiangxi Province - Xianghui Lu; Haina Zhang; Yixiu Han; Hua Bai; Erhui Li (Theoretical and Applied Climatology, 2022)

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Cloning and functional analysis of soluble acid invertase 2 gene (SbSAI-2) in sorghum - Wuyuntanmanda; Fen-Xia Han; Bao-Qing Dun; Ji Zhang; Zhi Wang; Yi Sui; Li Zhu; Gui-Ying Li (Planta, 2022)

Near-epicenter weather conditions several hours before strong earthquakes (Ms ≥ 6) - Tao Chen; Lei Li; Xiao-Xin Zhang; Qi-Ming Ma; Wen Li; Shuo Ti; Han Wu; Ren-Kang Li; Jing Luo; Jian-Feng Su (Natural Hazards, 2022)

Comparative transcriptomic analysis of Macrobrachium nipponense in response to Aeromonas veronii or Staphylococcus aureus infection - Chong Han; Zhipeng Zhang; Qiang Li; Qinghua Chen; Jianrong Huang (Journal of Oceanology and Limnology, 2022)

Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus - Han Jiang; Chunyan Li; Bo Zhang; Yongli Wu; Qiang Lin (Journal of Oceanology and Limnology, 2022)

Enhanced Production of Iturin A-2 Generated from Bacillus velezensis T701 and the Antitumor Activity of Iturin A-2 against Human Gastric Carcinoma Cells - Junpo Jiang; Mengnan Han; Shuangqing Fu; Jie Du; Shiying Wang; Honglei Zhang; Wei Li (International Journal of Peptide Research and Therapeutics, 2022)

The Protective Effect of Selenium on T-2-Induced Nephrotoxicity Is Related to the Inhibition of ROS-Mediated Apoptosis in Mice Kidney - Xuliang Zhang; Qi Wang; Jian Zhang; Miao Song; Bing Shao; Yanfei Han; Xu Yang; Yanfei Li (Biological Trace Element Research, 2022)

A method for precisely predicting satellite clock bias based on robust fitting of ARMA models - Guochao Zhang; Songhui Han; Jun Ye; Ruizhe Hao; Jingchao Zhang; Xia Li; Kun Jia (GPS Solutions, 2022)

Williamsia soli sp. nov., an actinobacterium isolated from soil at a thermal power plant in Yantai, China - Ming-Jing Zhang; Xue-Han Li; Li-Yang Peng; Shuai-Ting Yun; Zhuo-Cheng Liu; Yan-Xia Zhou (Archives of Microbiology, 2022)

Alteribacter salitolerans sp. nov., isolated from a saline-alkaline soil - Shuang Wang; Lei Sun; Manik Prabhu Narsing Rao; Guo-Hong Liu; Pin-Jiao Jin; Zhou-Yan Dong; Zheng-Han Lian; Xiao-Yu Hao; Ming-Yi Zhang; Wen-Jun Li (Archives of Microbiology, 2022)

Investigation on failure characteristic and instability mechanism of red sandstone including serrated joints under variable angle shear - Chao Han; Xiaolin Liu; Dejian Li; Jiwei Wang; Jin Zhang (Arabian Journal of Geosciences, 2022)

Geochemical characteristics and origin of Chang-9 crude oil of Triassic Yanchang Formation in Zhidan area, Ordos Basin, China - Zhengyu Wu; Shijia Chen; Chengshan Li; Jian Yu; Yibo Chang; Zixing Lu; Xin He; Haifeng Zhang; Han Meimei (Arabian Journal of Geosciences, 2022)

Environmental drivers of phytoplankton crops and taxonomic composition in northeastern Antarctic Peninsula adjacent sea area - Yubin Feng; Dong Li; Jun Zhao; Zhengbing Han; Jianming Pan; Gaojing Fan; Haisheng Zhang; Ji Hu; Haifeng Zhang; Jiaqi Wu; Qiuhong Zhu (Acta Oceanologica Sinica, 2022)

Biodiversity alleviates the decrease of grassland multifunctionality under grazing disturbance: A global meta‐analysis - Ruiyang Zhang; Dashuan Tian; Han Y. H. Chen; Eric W. Seabloom; Guodong Han; Shaopeng Wang; Guirui Yu; Zhaolei Li; Shuli Niu (Global Ecology and Biogeography, 2022)
Aim Biodiversity drives the delivery of multiple ecosystem functions related to carbon and nutrient cycling (ecosystem multifunctionality, EMF), and biodiversity and ecosystem functioning are strongly threatened by intensive grazing in grasslands. However, it remains unclear how biodiversity regulates EMF changes in response to intensive grazing. Location Global. Time period From 1992 to 2018. Major taxa studied Grassland. Methods Here, we conducted a global synthesis using 373 paired observations from 90 published studies to address the responses of plant diversity, EMF and their relationships to grazing disturbance depending on grazing intensity, livestock type, grazing duration, and climatic aridity. Results Our results showed that EMF significantly decreased with increasing grazing intensity, but the negative EMF response was alleviated at high levels of plant diversity. The grazing‐induced changes in EMF increased linearly with the changes in plant diversity, with the slopes increasing by 78.9% from light to heavy grazing. In addition, the grazing‐induced decrease of EMF was stronger with longer grazing duration and more arid climates. Structural equation models suggested that grazing intensity reduced EMF largely via decreasing plant diversity, whereas upsizing livestock type promoted EMF by increasing plant diversity. Main conclusions This study highlights the key role of biodiversity in mediating EMF in response to intensifying grazing disturbance. We call for conservation of biodiversity to maintain grassland multifunctionality and services.

Chemical constituent from the peel of Trichosanthes kirilowii Maxim and their NF-κB inhibitory activity - Xi Lei; Nan Li; Zisong Bai; Jingrui Di; Han Zhang; Pengzhi Dong; Peng Zhang (Natural Product Research, 2021)

Lathyrane diterpenoids from Jatropha podagrica and their antitumor activities in human osteosarcoma cells - Han-Tao Yuan; Qun-Feng Li; Tian Tian; Chun-Yan Zhang; Zou-Qin Huang; Chun-Xiang Fan; Ke Mei; Jie Zhou; Xiao-Xiang Zhai; Si-Bo Li; Jian-Yong Zhu (Natural Product Research, 2021)

Variations in soil properties rather than functional gene abundances dominate soil phosphorus dynamics under short-term nitrogen input - Bing Han; Jingjing Li; Kesi Liu; Hui Zhang; Xiaoting Wei; Xinqing Shao (Plant and Soil, 2021)

Photosynthetic acclimation during low-light-induced leaf senescence in post-anthesis maize plants - Han-Yu Wu; Li-An Liu; Lei Shi; Wang-Feng Zhang; Chuang-Dao Jiang (Photosynthesis Research, 2021)

Osteoarthritic infrapatellar fat pad aggravates cartilage degradation via activation of p38MAPK and ERK1/2 pathways - Zuoqing Zhou; Su’an Tang; Xiaoyu Nie; Yiqun Zhang; Delong Li; Yang Zhao; Yumei Cao; Jianwen Yin; Tianyu Chen; Guangfeng Ruan; Zhaohua Zhu; Xiaochun Bai; et al. (Inflammation Research, 2021)

Pollution characteristics, spatial distribution, and source identification of heavy metals in road dust in a central eastern city in China: a comprehensive survey - Guoyong Zhao; Ronglei Zhang; Yan Han; Jianing Meng; Qiang Qiao; Hetan Li (Environmental Monitoring and Assessment, 2021)

Karyotypic stability of Fragaria (strawberry) species revealed by cross-species chromosome painting - Manman Qu; Luyue Zhang; Kunpeng Li; Jianying Sun; Zongyun Li; Yonghua Han (Chromosome Research, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

The Common Occurrence of Theileria ovis in Tibetan Sheep and the First Report of Theileria sinensis in Yaks from Southern Qinghai, China - Ye Wang; Bo Wang; Qingxun Zhang; Ying Li; Ziwen Yang; Shuyi Han; Guohui Yuan; Shuangling Wang; Hongxuan He (Acta Parasitologica, 2021)

Warming reshaped the microbial hierarchical interactions - Yuqi Zhou; Baoyu Sun; Baohua Xie; Kai Feng; Zhaojing Zhang; Zheng Zhang; Shuzhen Li; Xiongfeng Du; Qi Zhang; Songsong Gu; Wen Song; Linlin Wang; et al. (Global Change Biology, 2021)
Global warming may alter microbially mediated ecosystem functions through reshaping of microbial diversity and modified microbial interactions. Here, we examined the effects of 5‐year experimental warming on different microbial hierarchical groups in a coastal nontidal soil ecosystem, including prokaryotes (i.e., bacteria and archaea), fungi, and Cercozoa, which is a widespread phylum of protists. Warming significantly altered the diversity and structure of prokaryotic and fungal communities in soil and additionally decreased the complexity of the prokaryotic network and fragmented the cercozoan network. By using the Inter‐Domain Ecological Network approach, the cross‐trophic interactions among prokaryotes, fungi, and Cercozoa were further investigated. Under warming, cercozoan–prokaryotic and fungal–prokaryotic bipartite networks were simplified, whereas the cercozoan–fungal network became slightly more complex. Despite simplification of the fungal–prokaryotic network, the strengthened synergistic interactions between saprotrophic fungi and certain prokaryotic groups, such as the Bacteroidetes, retained these phyla within the network under warming. In addition, the interactions within the fungal community were quite stable under warming conditions, which stabilized the interactions between fungi and prokaryotes or protists. Additionally, we found the microbial hierarchical interactions were affected by environmental stress (i.e., salinity and pH) and soil nutrients. Interestingly, the relevant microbial groups could respond to different soil properties under ambient conditions, whereas under warming these two groups tended to respond to similar soil properties, suggesting network hub species responded to certain environmental changes related to warming, and then transferred this response to their partners through trophic interactions. Finally, warming strengthened the network modules’ negative association with soil organic matters through some fungal hub species, which might trigger soil carbon loss in this ecosystem. Our study provides new insights into the response and feedback of microbial hierarchical interactions under warming scenario.

Environmental contamination with SARS‐CoV ‐2 in COVID ‐19 hospitals in Wuhan, China, 2020 - Wei Liu; Dingchen Li; Chaojie Yang; Fangyan Chen; Ruizhong Jia; Leili Jia; Xinyi Xia; Shanhong Fan; Qing Tan; Yuehua Ke; Yong Chen; Haifeng Li; et al. (Environmental Microbiology, 2021)
Summary Coronavirus disease 2019 (COVID‐19) pandemic has caused high number of infections and deaths of healthcare workers globally. Distribution and possible transmission route of SARS‐CoV‐2 in hospital environment should be clarified. We herein collected 431 environmental (391 surface and 40 air) samples in the intensive care unit (ICU) and general wards (GWs) of three hospitals in Wuhan, China from February 21 to March 4, 2020, and detected SARS‐CoV‐2 RNA by real‐time quantitative PCR. The viral positive rate in the contaminated areas was 17.8% (28/157), whereas there was no virus detected in the clean areas. Higher positive rate (22/59, 37.3%) was found in ICU than that in GWs (3/63, 4.8%). The surfaces of computer keyboards and mouse in the ICU were the most contaminated (8/10, 80.0%), followed by the ground (6/9, 66.7%) and outer glove (2/5, 40.0%). From 17 air samples in the contaminated areas, only one sample collected at a distance of around 30 cm from the patient was positive. Enhanced surface disinfection and hand hygiene effectively decontaminated the virus from the environment. This finding might help understand the transmission route and contamination risk of SARS‐CoV‐2 and evaluate the effectiveness of infection prevention and control measures in healthcare facilities.

Effect of Berberine Hydrochloride Treatment on Transcriptomic Response in Gill Tissue of Charybdis japonica Infected With Aeromonas hydrophila - Mingming Han; Yuxin Liu; Tongqing Zhang; Daming Li; Qichen Jiang; Zakaria Zuraini (Frontiers in Marine Science, 2021)
Berberine hydrochloride is the main active ingredient of Coptis chinensis, which has demonstrated significant antibacterial activity against bacteria. However, the molecular mechanism underlying its effects is unclear in crabs. In this study, we used transcriptome sequencing to investigate the molecules involved in the therapeutic and defensive responses of Charybdis japonica infected with 10 5 colony-forming units (CFU)/L of Aeromonas hydrophila following treatment with berberine hydrochloride. A total of 5,409 differentially expressed genes were observed after exposure of C. japonicus for 72 h to 100 mg/L berberine hydrochloride, 100 mg/L berberine hydrochloride plus injection of 10 5 CFU/L A. hydrophila , and a control group injected with equal amount of physiological saline solution. Enrichment analysis revealed that these genes were involved in metabolism, cellular processes, signal transduction, and immune function. The transcriptomic results indicated that exposure to berberine hydrochloride activated glutathione metabolism, oxidative phosphorylation, fatty acid degradation, retinol metabolism, pyruvate metabolism, and the hypoxia-inducible factor 1 signaling pathway. Transcriptomic analysis and relative mRNA level analysis also identified acid hydrolase genes and phagosomal genes as key factors regulating the adaptation of acid berberine-infused C. japonicus to infection with A. hydrophila , Based on the ability of berberine hydrochloride to induce acid hydrolase and phagosomal gene expression, which can in turn remove bacteria, immersion in berberine hydrochloride may remove A. hydrophila and thus improve the survival of C. japonica . The results of this study provided a new scientific basis for the potential role of berberine hydrochloride in the immune mechanisms of crabs.

Three new diterpenoids from Euphorbia peplus - Yan-Ni Chen; Qing-Yun Lu; Dong-Mei Li; Ying-Yao Li; Xue-Xue Pu; Bo-Ting Li; Xiao-Han Tang; Hong-Yu Tang; Shuai Liu; Lei Yang; Yu Zhang; Ying-Tong Di; et al. (Natural Product Research, 2021)

Identification and fine mapping of alien fragments associated with enhanced grain weight from Agropyron cristatum chromosome 7P in common wheat backgrounds - Yangyang Sun; Mingjie Lyu; Haiming Han; Shenghui Zhou; Yuqing Lu; Weihua Liu; Xinming Yang; Xiuquan Li; Jinpeng Zhang; Xu Liu; Lihui Li (Theoretical and Applied Genetics, 2021)

Impact of global warming on meteorological drought: a case study of the Songliao Plain, China - Guna Ari; Yongbin Bao; Hanfu Asi; Jiquan Zhang; Li Na; Lema Angge; Yulong Bao; Aru Han; Zhenhua Dong; ZhijunTong; Xingpeng Liu (Theoretical and Applied Climatology, 2021)

FHA domain of AGGF1 is essential for its nucleocytoplasmic transport and angiogenesis - Cui-Fang Zhang; Han-Ming Wang; Andong Wu; Yang Li; Xiao-Li Tian (Science China Life Sciences, 2021)

Genome-wide characterization and analysis of the anthocyanin biosynthetic genes in Brassica oleracea - Fengqing Han; Xiaoli Zhang; Limei Yang; Mu Zhuang; Yangyong Zhang; Yumei Liu; Zhansheng Li; Yong Wang; Zhiyuan Fang; Jialei Ji; Honghao Lv (Planta, 2021)

GhWRKY21 regulates ABA-mediated drought tolerance by fine-tuning the expression of GhHAB in cotton - Jiayu Wang; Lijun Wang; Yan Yan; Shuxin Zhang; Han Li; Zheng Gao; Chen Wang; Xingqi Guo (Plant Cell Reports, 2021)

Lipin1 Alleviates Autophagy Disorder in Sciatic Nerve and Improves Diabetic Peripheral Neuropathy - Meijian Wang; Min Xie; Shuyan Yu; Pan Shang; Cong Zhang; Xiaolin Han; Cuiqin Fan; Li Chen; Xianghua Zhuang; Shihong Chen (Molecular Neurobiology, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

A 168-year temperature recording based on tree rings and latitude differences in temperature changes in northeast China - Yangao Jiang; Yuting Cao; Junhui Zhang; Zhuo Li; Guoqiang Shi; Shijie Han; Cassius E. O. Coombs; Chuan Liu; Xiaoguang Wang; Junwei Wang; Lin Hao; Qi Xu; et al. (International Journal of Biometeorology, 2021)

Eutrophication model driven by light and nutrients condition change in sluice-controlled river reaches - Ming Dou; Li Liang; Yuping Han; Ruipeng Jia; Yan Zhang (Environmental Science and Pollution Research, 2021)

Exposure to 2,4-dichlorophenol, 2,4,6-trichlorophenol, pentachlorophenol and risk of thyroid cancer: a case-control study in China - Wan-Jun Yang; Hua-Bing Wu; Chi Zhang; Qi Zhong; Ming-Jun Hu; Jia-Liu He; Guo-Ao Li; Zhen-Yu Zhu; Jin-Liang Zhu; Huan-Huan Zhao; Han-Shuang Zhang; Fen Huang (Environmental Science and Pollution Research, 2021)

High-throughput sequencing revealed the expression profile and potential key molecules of the circular RNAs involved in the process of hypoxic adaptation in Tibetan chickens - Zengrong Zhang; Mohan Qiu; Huarui Du; Qingyun Li; Wu Gan; Xia Xiong; Chunlin Yu; Han Peng; Bo Xia; Xiaoyan Song; Li Yang; Chenming Hu; et al. (Biologia, 2021)

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

Carbon limitation overrides acidification in mediating soil microbial activity to nitrogen enrichment in a temperate grassland - Qiushi Ning; Stephan Hättenschwiler; Xiaotao Lü; Paul Kardol; Yunhai Zhang; Cunzheng Wei; Chengyuan Xu; Jianhui Huang; Ang Li; Junjie Yang; Jing Wang; Yang Peng; et al. (Global Change Biology, 2021)
Higher ecosystem nitrogen (N) inputs resulting from human activities often suppress soil microbial biomass and respiration, thereby altering biogeochemical cycling. Soil acidification and carbon (C) limitation may drive these microbial responses, yet their relative importance remains elusive, which limits our understanding of the longer term effects of increasing N inputs. In a field experiment with continuous N addition at seven different rates from 0 to 50 g N m −2 year −1 over 6 years in a temperate grassland of Inner Mongolia, China, we examined the responses of soil microbial biomass and respiration to changes in soil acidity and C availability by adding lime and/or glucose to soil samples. Soil microbial biomass and respiration did only weakly respond to increasing soil pH, but increased strongly in response to higher C availability with increasing N addition rates. Soil net N immobilization increased in response to glucose addition, and soil microbial biomass increased at higher rates than microbial respiration along the gradient of previous N addition rates, both suggesting increasingly reinforced microbial C limitation with increasing N addition. Our results provide clear evidence for strong N‐induced microbial C limitation, but only little support for soil acidity effects within the initial pH range of 4.73–7.86 covered by our study. Field data support this conclusion by showing reduced plant C allocation belowground in response to N addition, resulting in soil microbial C starvation over the long term. In conclusion, soil microbial biomass and respiration under N addition were strongly dependent on C availability, most likely originating from plant belowground C inputs, and was much less affected by changes in soil pH. Our data help clarify a long‐standing debate about how increasing N input rates affect soil microbial biomass and respiration, and improve the mechanistic understanding of the linkages between ecosystem N enrichment and C cycling.

Deformation and cooling history of the Central Qiangtang terrane, Tibetan Plateau and its tectonic implications - Wenjun Bi; Zhongpeng Han; Yalin Li; Chengming Li; Chengshan Wang; Jiawei Zhang; Jianyun Han; Haiyang He; Xinyu Qian; Tiankun Xu; Zining Ma (International Geology Review, 2021)

Pleosporalins H and I, two new heptaketides from the endophytic fungus Pleosporales sp. F46 by using OSMAC strategy - Hong-Xia Yang; Xiao-Ping Peng; Han Gao; Hui-Min Zhang; Zi-Ru Wang; Gang Li; Hong-Xiang Lou (Natural Product Research, 2021)

Master regulator NtrC controls the utilization of alternative nitrogen sources in Pseudomonas stutzeri A1501 - Zhimin Yang; Qin Li; Yongliang Yan; Xiubin Ke; Yueyue Han; Shaoyu Wu; Fanyang Lv; Yahui Shao; Shanshan Jiang; Min Lin; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2021)
Pseudomonas stutzeri A1501 is a model strain used to study associative nitrogen fixation, and it possesses the nitrogen regulatory NtrC protein in the core genome. Nitrogen sources represent one of the important factors affecting the efficiency of biological nitrogen fixation in the natural environment. However, the regulation of NtrC during nitrogen metabolism in P. stutzeri A1501 has not been clarified. In this work, a phenotypic analysis of the ntrC mutant characterized the roles of NtrC in nitrogen metabolism and the oxidative stress response of P. stutzeri A1501. To systematically identify NtrC-controlled gene expression, RNA-seq was performed to further analyse the gene expression differences between the wild-type strain and the ∆ ntrC mutant under nitrogen fixation conditions. A total of 1431 genes were found to be significantly altered by ntrC deletion, among which 147 associative genes had NtrC-binding sites, and the pathways for nitrogen fixation regulation, nitrogenous compound acquisition and catabolism and nitrate assimilation were discussed. Furthermore, the oxidative stress-related gene ( katB ), which was upregulated by ntrC deletion, was suggested to be a potential target gene of NtrC, thus highlighting the importance of NtrC in nitrogenase protection against oxygen damage. Based on these findings, we propose that NtrC is a high-ranking element in the regulatory network of P. stutzeri A1501 that controls a variety of nitrogen metabolic and oxidative stress responsive traits required for adaptation to complex rhizosphere environments.

Expression of the SPL-like gene LaSPL9 in Japanese larch (Larix leptolepis) is regulated by miR156 during somatic embryogenesis - Li-feng Zhang; Yan-ru Fan; Qian Lan; Li-wang Qi; Su-ying Han (Trees, 2021)

Tissue distribution of SARS-CoV-2 in non-human primates after combined intratracheal and intranasal inoculation - Tian-Zhang Song; Jian-Bao Han; Xiang Yang; Ming-Hua Li; Yong-Tang Zheng (Science China Life Sciences, 2021)

Influence of algal blooms on the efficacy of La/Al-based phoslock in the control of phosphorus release from sediment in shallow lakes: a microcosm study - Tianlun Han; Ming Kong; Chenjie Tang; Xueting Xu; Yanzhong Zhu; Yuexiang Gao; Tao Zhang; Yimin Zhang; Weixin Li (Journal of Soils and Sediments, 2021)

Spartina alterniflora saltmarsh soil organic carbon properties and sources in coastal wetlands - Jin-e Liu; Dailan Deng; Caiyu Zou; Ruiming Han; Yue Xin; Zihao Shu; Li-min Zhang (Journal of Soils and Sediments, 2021)

γ-Aminobutyric Acid Participates in the Adult-Phase Adventitious Rooting Recalcitrance - Xu Li; Xiaozhao Xu; Fei Shen; Wei Li; Changpeng Qiu; Ting Wu; Yi Wang; Xuefeng Xu; Zhenhai Han; Xinzhong Zhang (Journal of Plant Growth Regulation, 2021)
In many tree species especially the rooting-recalcitrant woody perennials, the adventitious root (AR) in the juvenile phase can be easily induced by exogenous auxin, but AR formation becomes recalcitrant in the adult phase. Also, it is reported that the γ-aminobutyric acid (GABA) inhibits primary root growth in Arabidopsis and the AR formation in poplar ( Populus ssp). So far, how GABA affects or is affected by the ontogenetic phase or auxin remains unclear. Here, we used an apple rootstock, Malus xiaojinensis, and tobacco ( Nicotiana benthamiana ) to investigate this question. We first analyzed the content of GABA, the activity of GABA synthetic enzyme GAD, and the expression of the coding gene MxGADs, respectively, in leafy cuttings of juvenile and adult phase. Next, the effect of exogenous GABA on AR formation was examined in in vitro shoots of M. xiaojinensis and tobacco. Interestingly, significant and consistent increases in GABA concentration, GAD activity, and expression of MxGAD genes in response to exogenous indole butyric acid (IBA) were detected in adult-phase cuttings, but not in juvenile-phase cuttings. Exogenous GABA application inhibited the AR formation by delaying rooting time and reducing root number and the total root length in in vitro shoots of both M. xiaojinensis and tobacco. The expression of MxPIN members increased in response to IBA application, but these changes were restrained by the addition of GABA. These results indicate that both the loss of juvenility and IBA are required to trigger GABA accumulation. GABA may affect the AR formation as a co-actor by inhibiting polar auxin transport. Together, these findings facilitate the understanding of the regulatory network among GABA, juvenility, and auxin signaling on the AR formation.

Globular adiponectin inhibits osteoblastic differentiation of vascular smooth muscle cells through the PI3K/AKT and Wnt/β-catenin pathway - Yun Zhou; Li-Long Wei; Rui-Ping Zhang; Cheng-Wu Han; Yongtong Cao (Journal of Molecular Histology, 2021)
Lipid metabolism is closely related to the improvement of vascular calcification (VC) in chronic kidney disease (CKD). Globular adiponectin (gAd) has been reported to be involved in the development of VC in CKD, but the detailed regulatory role remains unclear. The present study is aimed to investigate the biological function and the underlying regulation mechanism of gAd in the process of VC during CKD. Vascular smooth muscle cells (VSMCs) calcification was determined by Alizarin Red S staining. Protein signaling related with VC was tested by western blotting. The expression and intracellular localization of runt-related transcription factor 2 (Runx2) was detected by immunofluorescence and uraemic rat with VC was established by a two-step nephrectomy. Combined with the results of Alizarin Red S staining, we discovered that β-glycerophosphate (β-Gp)-induced the osteoblastic differentiation of VSMCs was significantly reversed by gAd treatment. Along with the VSMCs calcification and the increase of Runx2 in β-Gp-exposed VSMCs, the activities of protein kinase B (AKT) and Wnt/β-catenin pathway were enhanced, but that were counteracted by the exposure of gAd in rat and human VSMCs. After administration with agonists of the Wnt (SKL2001) and AKT (SC79), there appeared more osteoblastic differentiation and higher expression of Runx2 in gAd-treated VSMCs, but showing lower impact in the presence of SC79 than that in the presence of SKL2001. In the in vivo experiments, intravenous injection of gAd also significantly inhibited VC and Runx2 level in uraemic rat in a dose-dependent manner, possibly through regulating Wnt/β-catenin pathway. This study demonstrates that gAd ameliorates osteoblastic differentiation of VSMCs possibly by blocking PI3K/AKT and Wnt/β-catenin signaling transduction. The findings provide an important foundation for gAd in treating VC in kidney diseases.

Long-term high-intensity interval training increases serum neurotrophic factors in elderly overweight and obese Chinese adults - Xi Li; Tianyu Han; Xu Zou; Han Zhang; Wenpin Feng; Han Wang; Yulin Shen; Li Zhang; Guoliang Fang (European Journal of Applied Physiology, 2021)

Diversity, abundance, and distribution of anammox bacteria in shipping channel sediment of Hong Kong by analysis of DNA and RNA - Xiaowei Zhang; Han Meng; Yuchun Yang; Wensheng Lan; Weidong Wang; Paul K. S. Lam; Xiao-Yan Li; Ji-Dong Gu (Ecotoxicology, 2021)

Regional brain network and behavioral alterations in EGR3 gene transfected rat model of schizophrenia - Wenwen Gao; Guangfei Li; Xiaowei Han; Zeyu Song; Shuai Zhao; Feiyi Sun; Hong Ma; Ailing Cui; Yige Wang; Xiuxiu Liu; Yue Chen; Lu Zhang; et al. (Brain Imaging and Behavior, 2021)

Stable isotopes (δ2H) in feathers identify non-breeding origins of the endangered Jankowski’s Bunting - Zheng Han; Hai-Tao Wang; Kevin J. Kardynal; Keith A. Hobson; Wei-Ping Shang; li-shi Zhang; Yun-lei Jiang; Frédéric Jiguet (Journal of Ornithology, 2021)

Effects on the STAT3-shRNA in Non-Small-Cell Lung Cancer Therapy: Design, Induction of Apoptosis, and Conjugation with Chitosan-Based Gene Vectors - Wangwang Zhang; Yan Zhang; Zhiwen Jiang; Le Sun; Litong Wang; Zhiyang Gu; Wenya Li; Lili Guo; Xiaotong Chen; Haibin Zhang; Baoqin Han; Jing Chang (Journal of Ocean University of China, 2021)

Raspberry (Rubus idaeus L.) NCED1 gene enhances high salinity and cold tolerance in Arabidopsis - Guohui Yang; Yuxiao Chen; Heng Yu; Hang Zhang; Deguo Han; Xiaoyu Guo; Enqing Yan; Hanyi Quan; Tiemei Li (In Vitro Cellular & Developmental Biology - Plant, 2021)

Highly sialylated mucin-type glycopeptide from porcine intestinal mucosa after heparin extraction: O-glycan profiling and immunological activity evaluation - Xin Zhang; Chen Wang; Qing Han; Xuan Chen; Guoyun Li; Guangli Yu (Glycoconjugate Journal, 2021)

Atmospheric-Boundary-Layer-Height Variation over Mountainous and Urban Sites in Beijing as Derived from Radar Wind-Profiler Measurements - Raman Solanki; Jianping Guo; Jian Li; Narendra Singh; Xiaoran Guo; Yi Han; Yanmin Lv; Jian Zhang; Boming Liu (Boundary-Layer Meteorology, 2021)

Circular RNA circ_Cabin1 promotes DNA damage in multiple mouse organs via inhibition of non-homologous end-joining repair upon PM2.5 exposure - Huixian Zeng; Meizhen Li; Qiuhan Hua; Yufei Liu; Yueting Shao; Qinqin Diao; Yihui Ling; Han Zhang; Miaoyun Qiu; Jialu Zhu; Xun Li; Rong Zhang; et al. (Archives of Toxicology, 2021)

Shifts in Nitrogen Removal Performance and Microbial Communities in Constructed Wetlands After Short-term Exposure to Titanium Dioxide Nanoparticles - Rui Han; Kexin Li; Chenzheng We; Tao He; Jingru Liu; Renduo Zhang; Li Wan; Yinghai Wu (Water, Air, & Soil Pollution, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Descending Modulation of Spinal Itch Transmission by Primary Somatosensory Cortex - Zi-Han Wu; Han-Yu Shao; Yuan-Yuan Fu; Xiao-Bo Wu; De-Li Cao; Sheng-Xiang Yan; Wei-Lin Sha; Yong-Jing Gao; Zhi-Jun Zhang (Neuroscience Bulletin, 2021)

Stability mechanism recognition and failure risk assessment on a high slope by synthesizing different analysis methods - Changqing Qi; Liuyang Li; Ruoqi Li; Feifei Gan; Wentao Zhang; Hui Han (Natural Hazards, 2021)

The advances of topology optimization techniques in orthopedic implants: A review - Naichao Wu; Shan Li; Boyan Zhang; Chenyu Wang; Bingpeng Chen; Qing Han; Jincheng Wang (Medical & Biological Engineering & Computing, 2021)

Synthesis of a novel ZnFe2O4/porous biochar magnetic composite for Th(IV) adsorption in aqueous solutions - W. D. Wang; Y. X. Cui; L. K. Zhang; Y. M. Li; P. Sun; J. H. Han (International Journal of Environmental Science and Technology, 2021)

Production, Purification and Characterization of ‘Iturin A-2’ a Lipopeptide with Antitumor Activity from Chinese Sauerkraut Bacterium Bacillus velezensis T701 - Junpo Jiang; Honglei Zhang; Chao Zhang; Mengnan Han; Jie Du; Xueli Yang; Wei Li (International Journal of Peptide Research and Therapeutics, 2021)

Efficiently immobilizing uranium (VI) by oxidized carbon foam - Hongliang Bao; Chunyu Xie; Ling Han; Zenghui Yue; Yuan Qian; Linjuan Zhang; Zi-Jian Li; Huangjie Lu; Jian Lin; Jian-Qiang Wang (Environmental Science and Pollution Research, 2021)

Methane Concentration in the Heartwood of Living Trees and Estimated Methane Emission on Stems in Upland Forests - Zhi-Ping Wang; Huan-Long Li; Hong-Hui Wu; Shi-Jie Han; Jian-Hui Huang; Xi-Mei Zhang; Xing-Guo Han (Ecosystems, 2021)

Aspergillus fumigatus Induces the Release of IL-8 and MCP-1 by Activating Nuclear Transcription Through Dectin-1 and CR3 Receptors in Alveolar Epithelial Cells - Yanxi Liu; Zhiqian Li; Shuo Wang; Changjian Zhang; Li Han; Qun Sun; Xuelin Han (Current Microbiology, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Human Methylmercury Exposure and Potential Impacts in Central Tibet: Food and Traditional Tibetan Medicine - Menghan Cheng; Maodian Liu; Dou Li; Qing Luo; Zhihao Zhang; Liuliang Yuan; Chenghao Yu; Han Xie; Huiming Lin; Qianru Zhang; De Ji; Xuejun Wang (Bulletin of Environmental Contamination and Toxicology, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

Experimental Study of Large-Temperature-Range and Long-Period Monitoring for LNG Marine Auxiliary Based on Fiber Bragg Grating Temperature Measurement - Fenghui Han; Zhe Wang; Hefu Zhang; Dongxing Wang; Wenhua Li; Wenjian Cai (Journal of Marine Science and Engineering, 2021)
Temperature is a key variable to evaluate the energy consumption and thermodynamic performance of traditional marine auxiliary machinery, chillers and piping systems. In particular, for the cryogenic storage tanks and fuel gas supply systems of LNG ships, explosion-proof and low-temperature-resistance properties bring new challenges to the onboard temperature measurement and monitoring. In order to promote the development of high-performance and safer monitoring systems for LNG ships, this paper adopted fiber Bragg grating (FBG) technology to ensure the measurement safety and accuracy of temperature sensors, and performs a series of experiments in a large temperature range on the chiller, pipeline, and cryogenic storage tank of an LNG ship and their long-term reliabilities. Firstly, the principle and composition of the designed FBG temperature sensors are introduced in detail, and the measurement accuracy and range of different metal-coated optical fibers were tested in a large temperature range and compared against the traditional thermistors. Then, the effects of different operating conditions of the LNG marine chiller system and cryogenic storage tank on the temperature measurements were investigated. In addition, the drift degrees of the optical fibers and industrial thermistors were analyzed to figure out their reliabilities for long-term temperature measurements. The results showed that for the long-period (16 months) monitoring of LNG ships in a large temperature range (105–315 K) under different shipping conditions, the optical temperature measurement based on FBG technology has sufficient accuracy and dynamic sensitivity with a higher safety than the traditional thermoelectric measurement. Besides, the ship vibration, ambient humidity, and great temperature changes have little impact on its measurement reliability and drifts. This research can provide references and technical supports to the performance testing systems of LNG ships and other relevant vessels with stricter safety standards.

Triterpene saponins from tea seed pomace ( Camellia oleifera Abel) and their cytotoxic activity on MCF-7 cells in vitro - Xin-Fu Zhang; Ying-Ying Han; Tai-Mei Di; Li-Ping Gao; Tao Xia (Natural Product Research, 2021)

An object-based graph model for unsupervised change detection in high resolution remote sensing images - Junzheng Wu; Biao Li; Yao Qin; Weiping Ni; Han Zhang (International Journal of Remote Sensing, 2021)

Correction to: Activation of Sigma-1 Receptor Enhanced Pericyte Survival Via the Interplay between Apoptosis and Autophagy: Implications for Blood–Brain Barrier Integrity in Stroke - Yuan Zhang; Xiaotian Zhang; Qiangqiang Wei; Shuo Leng; Cai Li; Bing Han; Ying Bai; Huibin Zhang; Honghong Yao (Translational Stroke Research, 2021)

Identification of glutathione transferase gene associated with partial resistance to Sclerotinia stem rot of soybean using genome-wide association and linkage mapping - Zou Jianan; Wenjing Li; Yuting Zhang; Wei Song; Haipeng Jiang; Jingyun Zhao; Yuhang Zhan; Weili Teng; Lijuan Qiu; Xue Zhao; Yingpeng Han (Theoretical and Applied Genetics, 2021)

The downregulation of PpPG21 and PpPG22 influences peach fruit texture and softening - Ming Qian; Ze Xu; Zehua Zhang; Qin Li; Xiangyan Yan; Hangkong Liu; Mingyu Han; Furui Li; Jicheng Zheng; Dong Zhang; Caiping Zhao (Planta, 2021)

Inhibition of Ca2+-dependent protein kinase C rescues high calcium–induced pro-arrhythmogenic cardiac alternans in rabbit hearts - Pei-pei Zhang; Liangkun Hu; You-jia Tian; Zefu Zhang; Pei-hua Zhang; Yan-yan Yang; Shi-han Li; Jihua Ma (Pflügers Archiv - European Journal of Physiology, 2021)

Pinocembrin-7-Methylether Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity via Modulating Nrf2 Induction Through AKT and ERK Pathways - Zhi-Cong Zou; Ji-Jun Fu; Yuan-Ye Dang; Qian Zhang; Xiu-Fen Wang; Han-Bin Chen; Xue-Jing Jia; Simon Ming-Yuen Lee; Chu-Wen Li (Neurotoxicity Research, 2021)

Comparison of clinical characteristics and outcomes between respiratory syncytial virus and influenza-related pneumonia in China from 2013 to 2019 - Liang Chen; Xiudi Han; YanLi Li; Chunxiao Zhang; Xiqian Xing (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Genomic selection to introgress exotic maize germplasm into elite maize in China to improve kernel dehydration rate - Hongjun Yong; Nan Wang; Xiaojun Yang; Fengyi Zhang; Juan Tang; Zhiyuan Yang; Xinzhe Zhao; Yi Li; Mingshun Li; Degui Zhang; Zhuanfang Hao; Jianfeng Weng; et al. (Euphytica, 2021)

Temperature and Moisture Modulate the Contribution of Soil Fauna to Litter Decomposition via Different Pathways - Bo Tan; Rui Yin; Jian Zhang; Zhenfeng Xu; Yang Liu; Shuqin He; Li Zhang; Han Li; Lixia Wang; Sining Liu; Chengming You; Changhui Peng (Ecosystems, 2021)

Antimicrobial nanomedicine for ocular bacterial and fungal infection - Wenjie Fan; Haijie Han; Yaoyao Chen; Xiaobo Zhang; Yifan Gao; Su Li; Qiao Jin; Jian Ji; Ke Yao (Drug Delivery and Translational Research, 2021)

Impact of early spring sea ice in Barents Sea on midsummer rainfall distribution at Northeast China - Tingting Han; Minghua Zhang; Jiawen Zhu; Botao Zhou; Shangfeng Li (Climate Dynamics, 2021)

Frequency-specific altered global signal topography in drug-naïve first-episode patients with adolescent-onset schizophrenia - Xiao Wang; Wei Liao; Shaoqiang Han; Jiao Li; Yifeng Wang; Yan Zhang; Jingping Zhao; Huafu Chen (Brain Imaging and Behavior, 2021)

Increased cerebral blood flow is correlated with neurocognitive impairment in long-term hemodialysis patients: an arterial spin labeling MRI study - Chao Chai; Mengjie Zhang; Huiying Wang; Jinping Li; Tong Zhang; Yingying Han; Jinxia Zhu; Xianchang Zhang; Shuang Xia; Wen Shen (Brain Imaging and Behavior, 2021)

Mild encephalitis/encephalopathy with a reversible splenial lesion associated with respiratory syncytial virus infection in infants - Xue-Lin Li; Jinming Han; Zhong-Rui Yan; Bing-Wei Zhang; Hai-Yang Wang (Journal of NeuroVirology, 2021)

Genome-wide association analysis for yield-related traits at the R6 stage in a Chinese soybean mini core collection - Xiangnan Li; Yang Zhou; Yuanpeng Bu; Xinfang Wang; Yumei Zhang; Na Guo; Jinming Zhao; Han Xing (Genes & Genomics, 2021)

Sum of High-Risk Gene Mutation (SHGM): A Novel Attempt to Assist Differential Diagnosis for Adrenocortical Carcinoma with Benign Adenoma, Based on Detection of Mutations of Nine Target Genes - Guo-Yang Zheng; Xue-Bin Zhang; Han-Zhong Li; Yu-Shi Zhang; Jian-Hua Deng; Xing-Cheng Wu (Biochemical Genetics, 2021)
There has been no research on applying gene detection to differential diagnosis of adrenocortical carcinoma (ACC). We attempted to explore a novel auxiliary method for differential diagnosis between ACC with benign adrenocortical adenoma (ACA), based on mutations of target genes in tissues. Nine genes were chosen as target genes, including TP53, CTNNB1, ARMC5, PRKAR1A, ZNRF3, RB1, APC, MEN1, and RPL22 . Exons sequencing of target genes were performed in 98 cases of tissue samples by FastTarget technology, including 41 ACC tissues, 32 ACA tissues, and 25 normal adrenal gland tissues. Significant mutations were detected and identified, and the clinical information was collected, for further comparative analysis and application to assist differential diagnosis of ACC. We identified 132 significant gene mutations and 227 significant mutation sites in 37 ACC tissues, much more than ACA and normal adrenal gland tissues. Mutation rates of 6 genes in ACC tissues were obviously higher than ACA tissues, including ZNRF3, ARMC5, TP53, APC, RB1, and PRKAR1A , regarded as high-risk genes. The sum of mutated high-risk genes detected in each sample was denominated sum of high-risk gene mutation (SHGM), and the rates of SHGM > 0 and SHGM > 1 in ACC tissues were 73.0% and 62.2%, respectively, both obviously higher than those in ACA tissues, with significant statistic differences. Especially for 8 cases of ACC with diameter 0 and SHGM > 1 were found in 6 samples (75%) and 4 samples (50%), respectively. However, no relevance was found between SHGM and clinical characteristics of ACC. We identified 6 high-risk genes in ACC tissues, with significantly higher mutation rates than ACA or normal adrenal gland tissues. The sum of mutated high-risk genes detected in ACC tissues was denominated SHGM, which was potential to assist the differential diagnosis of ACC with ACA, especially for the small-size ACC.

Genetic changes and evolutionary analysis of canine circovirus - Lin Wang; Yifan li; Zhiyuan Guo; Ying Yi; Han Zhang; Haikun Shangguan; Chengshi Huang; Junwei Ge (Archives of Virology, 2021)

Correction to: Identification and molecular characterization of tea‑oil camellia‑associated totivirus 1 - Z.-Y. Zhang; H. Huang; X. X. Han; R. Li; L.-P. Wu; L. Wu (Archives of Virology, 2021)

Identification and molecular characterization of tea-oil camellia-associated totivirus 1 - Z.-Y. Zhang; H. Huang; X. X. Han; R. Li; L.-P. Wu; L. Wu (Archives of Virology, 2021)

Microbacterium helvum sp. nov., a novel actinobacterium isolated from cow dung - Xiao Li; Lida Zhang; Fuyan Huang; Junwei Zhao; Han Wang; Yanjie Jiao; Lulu Qian; Xiangjing Wang; Wensheng Xiang (Archives of Microbiology, 2021)

Aquiflexum lacus sp. nov., isolated from a lake sediment sample - Jianrong Huang; Mingxian Han; Baozhu Fang; Jian Yang; Haiyi Xiao; Xiying Zhang; Jibin Han; Dongmei Yu; Hongchen Jiang; Wenjun Li (Archives of Microbiology, 2021)

Wheat-root associated prokaryotic community: interplay between plant selection and location - Yuyin Zheng; Zhihan Feng; Jialong Wang; Xiaoman Huang; Li Lei; Xue Zhang; Huili Cao; Dandan Fan; Minjie Yao; Dejun Han; Xiangzhen Li (Plant and Soil, 2021)

Deep Learning Model for the Automated Detection and Histopathological Prediction of Meningioma - Hua Zhang; Jiajie Mo; Han Jiang; Zhuyun Li; Wenhan Hu; Chao Zhang; Yao Wang; Xiu Wang; Chang Liu; Baotian Zhao; Jianguo Zhang; Kai Zhang (Neuroinformatics, 2021)

Characteristics of RNA alternative splicing and its potential roles in ginsenoside biosynthesis in a single plant of ginseng, Panax ginseng C.A. Meyer - Yilai Han; Lei Zhu; Li Li; Yanfang Wang; Mingzhu Zhao; Kangyu Wang; Chunyu Sun; Jing Chen; Lingyu Liu; Ping Chen; Jun Lei; Yi Wang; et al. (Molecular Genetics and Genomics, 2021)

Correction to: TAK1 is involved in sodium L‑lactate‑stimulated p38 signaling and promotes apoptosis - Qingen Da; Zilong Yan; Zhangfu Li; Zhen Han; Mingming Ren; Lei Huang; Xiaowei Zhang; Jikui Liu; Tao Wang (Molecular and Cellular Biochemistry, 2021)

Curcumin protects against inflammation and lung injury in rats with acute pulmonary embolism with the involvement of microRNA-21/PTEN/NF-κB axis - Dean Liang; Zhiguo Wen; Wanli Han; Wenming Li; Longfei Pan; Ruipeng Zhang (Molecular and Cellular Biochemistry, 2021)

Identification of potential sex-related genes in Siniperca chuatsi - Qiaoying Zhu; Chong Han; Cheng Peng; Xingni Zhou; Chongwei Wang; Linqiang Han; Shuisheng Li; Guifeng Li; Haoran Lin; Yong Zhang (Journal of Oceanology and Limnology, 2021)

Fusarium solani G6, a novel vitexin-producing endophytic fungus: characterization, yield improvement and osteoblastic proliferation activity - Pei-jia Tang; Zhi-hui Zhang; Li-li Niu; Cheng-bo Gu; Wen-yi Zheng; Hai-chao Cui; Xiao-han Yuan (Biotechnology Letters, 2021)

Establishment of an indirect ELISA-based method involving the use of a multiepitope recombinant S protein to detect antibodies against canine coronavirus - Yun-Feng Hao; Shao-Han Li; Guang-Zhi Zhang; Yi Xu; Guang-zong Long; Xiao-xiong Lu; Shang-Jin Cui; Tong Qin (Archives of Virology, 2021)

Biological characteristics and salt-tolerant plant growth-promoting effects of an ACC deaminase-producing Burkholderia pyrrocinia strain isolated from the tea rhizosphere - Lizhen Han; Hong Zhang; Yu Xu; Ying Li; Jing Zhou (Archives of Microbiology, 2021)

Inversion of the Degradation Coefficient of Petroleum Hydrocarbon Pollutants in Laizhou Bay - Shengmao Huang; Haiwen Han; Xiuren Li; Dehai Song; Wenqi Shi; Shufang Zhang; Xianqing Lv (Journal of Marine Science and Engineering, 2021)
When petroleum hydrocarbon pollutants enter the ocean, besides the migration under hydrodynamic constraints, their degradation due to environmental conditions also occurs. However, available observations are usually spatiotemporally disperse, which makes it difficult to study the degradation characteristics of pollutants. In this paper, a model of transport and degradation is used to estimate the degradation coefficient of petroleum hydrocarbon pollutants with the adjoint method. Firstly, the results of a comprehensive physical–chemical–biological test of the degradation of petroleum hydrocarbon pollutants in Laizhou Bay provide a reference for setting the degradation coefficient on the time scale. In ideal twin experiments, the mean absolute errors between observations and simulation results obtain an obvious reduction, and the given distributions can be inverted effectively, demonstrating the feasibility of the model. In a practical experiment, the actual distribution of petroleum hydrocarbon pollutants in Laizhou Bay is simulated, and the simulation results are in good agreement with the observed ones. Meanwhile, the spatial distribution of the degradation coefficient is inverted, making the simulation results closer to the actual observations.

Proteome landscape and spatial map of mouse primordial germ cells - Pan Wang; Yilong Miao; Xiao-Han Li; Na Zhang; Qilong Wang; Wei Yue; Shao-Chen Sun; Bo Xiong; Jie Qiao; Mo Li (Science China Life Sciences, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Regulation of mGluR1 on the Expression of PKC and NMDAR in Aluminum-Exposed PC12 Cells - Chanting He; Xiaoyan Zhao; Huan Li; Fei Wang; Jingsi Zhang; Yanni Wang; Yingchao Han; Chunman Yuan; Qiao Niu (Neurotoxicity Research, 2021)

Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment - Rui-Yuan Zhang; Jie-Bai Tu; Rui-Tu Ran; Wen-Xuan Zhang; Qiang Tan; Ping Tang; Tao Kuang; Shu-Qun Cheng; Cheng-Zhi Chen; Xue-Jun Jiang; Chang Chen; Ting-Li Han; et al. (Neurotoxicity Research, 2021)

Different posterior hippocampus and default mode network modulation in young APOE ε4 carriers: a functional connectome-informed phenotype longitudinal study - Li Juan Zheng; Li Lin; U. Joseph Schoepf; Akos Varga-Szemes; Rock H. Savage; Han Zhang; Yun Fei Wang; Xin Yuan Zhang; Song Luo; Ya Liu; Gui Fen Yang; Guang Ming Lu; et al. (Molecular Neurobiology, 2021)

The Knowledge and Attitude Towards Advance Care Planning Among Chinese Patients with Advanced Cancer - Xiao-Ting Hou; Yu-Han Lu; Hong Yang; Ren-Xiu Guo; Yun Wang; Li-Hong Wen; Ya-Ru Zhang; Hong-Yu Sun (Journal of Cancer Education, 2021)

Shattering-resistance of an elite soybean variety ‘Heihe 43’ and identification of shattering-resistant genes - Dezhi Han; Jianan Han; Siqi Jiang; Bohong Su; Bo Zhang; Zhangxiong Liu; Hongrui Yan; Li-Juan Qiu (Euphytica, 2021)

Intraspecific recurrent selection in V. vinifera: an effective method for breeding of high quality, disease-, cold-, and drought -resistant grapes - Zhi-Lei Wang; Ting-Ting Xue; Fei-Fei Gao; Liang Zhang; Xing Han; Ying Wang; Miao Hui; Dong Wu; Hua Li; Hua Wang (Euphytica, 2021)

Acute effects of ambient air pollution on clinic visits of college students for upper respiratory tract infection in Wuhan, China - Faxue Zhang; Han Zhang; Chuangxin Wu; Miaoxuan Zhang; Huan Feng; Dejia Li; Wei Zhu (Environmental Science and Pollution Research, 2021)

Phthalate exposure in association with the use of personal care products among general population from Shanghai - Jin Qin; Ruihua Dong; Min Wu; Yaqun Yuan; Han Zhang; Pai Meng; Meiru Zhang; Jingsi Chen; Shuguang Li; Bo Chen (Environmental Science and Pollution Research, 2021)

Disrupted pathways from frontal-parietal cortex to basal ganglia and cerebellum in patients with unmedicated obsessive compulsive disorder as observed by whole-brain resting-state effective connectivity analysis – a small sample pilot study - Wei Liu; Minghui Hua; Jun Qin; Qiuju Tang; Yunyi Han; Hongjun Tian; Daxiang Lian; Zhengqing Zhang; Wenqiang Wang; Chunxiang Wang; Ce Chen; Deguo Jiang; et al. (Brain Imaging and Behavior, 2021)

Paleoclimatic proxies from global closed basins and the possible beginning of Anthropocene - Yu Li; Qin Han; Lu Hao; Xinzhong Zhang; Dawei Chen; Yuxin Zhang; Lingmei Xu; Wangting Ye; Simin Peng; Yichan Li; Zhuowen Feng; Hebin Liu (Journal of Geographical Sciences, 2021)

Overcoming diverse homologous recombinations and single chimeric guide RNA competitive inhibition enhances Cas9‐based cyclical multiple genes coediting in filamentous fungi - Youzhi Miao; Yanwei Xia; Yanqiong Kong; Han Zhu; Huiling Mei; Pan Li; Haichao Feng; Weibing Xun; Zhihui Xu; Nan Zhang; Dongyang Liu; Qirong Shen; et al. (Environmental Microbiology, 2021)
Summary Deciphering the complex cellular behaviours and advancing the biotechnology applications of filamentous fungi increase the requirement for genetically manipulating a large number of target genes. The current strategies cannot cyclically coedit multiple genes simultaneously. In this study, we firstly revealed the existence of diverse homologous recombination (HR) types in marker‐free editing of filamentous fungi, and then, demonstrated that sgRNA efficiency‐mediated competitive inhibition resulted in the low integration of multiple genetic sites during coediting, which are the two major obstacles to limit the efficiency of cyclically coediting of multiple genes. To overcome these obstacles, we developed a biased cutting strategy by Cas9 to greatly enhance the desired HR type and applied a new selection marker labelling strategy for multiple donor DNAs, in which only the donor DNA with the lowest sgRNA efficiency was labelled. Combined with these strategies, we successfully developed a convenient method for cyclically coediting multiple genes in different filamentous fungi. In addition, diverse HRs resulted in a useful and convenient one‐step approach for gene functional study combining both gene disruption and complementation. This research provided both a useful one‐step approach for gene functional study and an efficient strategy for cyclically coediting multiple genes in filamentous fungi.

Kelp aquaculture in China: a retrospective and future prospects - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
Globally, China has the largest scale of kelp cultivation and production operations. However, its kelp aquaculture industry is suffering from declining germplasm diversity, degradation of agronomic traits, the presence of polluted environments, changing ocean conditions and increasing anthropological interference. This review covers two of the most commercially important kelp species in China, viz. Saccharina japonica and Undaria pinnatifida . It summarizes the history of their cultivation, production, economic and ecological benefits, their breeding programmes (e.g. inter‐ and intra‐specific hybridization and marker‐assisted selection) and efforts towards population genetic diversity and conservation. The article focuses on three significant challenges, for example genetic cross‐contamination between the wild and farmed kelp populations, ocean warming and ocean acidification. Accordingly, we outline the steps required to provide several intervention measures, for example (i) collection and preservation of wild and cultivated kelp germplasm; (ii) selection of suitable cultivation sites under changing environmental conditions; (iii) developing stress‐resistant cultivars; and finally, (iv) adoption of innovative cultivation models. The review concludes with genome‐based, designs for molecular breeding and calls for the establishment of an East Asian Kelp Consortium (EAKC). Collectively, the Chinese kelp industry could provide beneficial goods and services, for example bioenergy to fine chemicals and environmental benefits, such as carbon capture, pH amelioration and provision of habitat for many other marine species of commercial value. The strategies proposed in this article thus have the potential to not only improve but also reinvigorate the kelp industry in China and nearby Japan and Korea, in the context of both environmental health and economic benefits.

Cover Image - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
The cover image is based on the Review Article Kelp aquaculture in China: A retrospective and future prospects by Zi‐Min Hu et al., https://doi.org/10.1111/raq.12524 . image

Difference Analysis on Sandstone Permeability After Treatment at Different Temperatures During the Failure Process: A Case Study of Sandstone in Chongqing, China - Weijing Xiao; Dongming Zhang; Haitao Li; Guo Yu; Han Yang; Beichen Yu (Pure and Applied Geophysics, 2021)

Taste Masking Study Based on an Electronic Tongue: the Formulation Design of 3D Printed Levetiracetam Instant-Dissolving Tablets - Zengming Wang; Jingru Li; Xiaoxuan Hong; Xiaolu Han; Boshi Liu; Xianfu Li; Hui Zhang; Jing Gao; Nan Liu; Xiang Gao; Aiping Zheng (Pharmaceutical Research, 2021)
Purpose Proper taste-masking formulation design is a critical issue for instant-dissolving tablets (IDTs). The purpose of this study is to use the electronic tongue to design the additives of the 3D printed IDTs to improve palatability. Methods A binder jet 3D printer was used to prepare IDTs of levetiracetam. A texture analyzer and dissolution apparatus were used to predict the oral dispersion time and in vitro drug release of IDTs, respectively. The palatability of different formulations was investigated using the ASTREE electronic tongue in combination with the design of experiment and a model for masking bitter taste. Human gustatory sensation tests were conducted to further evaluate the credibility of the results. Results The 3D printed tablets exhibited rapid dispersion (<30 s) and drug release (2.5 min > 90%). The electronic tongue had an excellent ability of taste discrimination, and levetiracetam had a good linear sensing performance based on a partial least square regression analysis. The principal component analysis was used to analyze the signal intensities of different formulations and showed that 2% sucralose and 0.5% spearmint flavoring masked the bitterness well and resembled the taste of corresponding placebo. The results of human gustatory sensation test were consistent with the trend of the electronic tongue evaluation. Conclusions Owing to its objectivity and reproducibility, this technique is suitable for the design and evaluation of palatability in 3D printed IDT development.

Resolvin D1 Attenuates Innate Immune Reactions in Experimental Subarachnoid Hemorrhage Rat Model - Guang-Jie Liu; Tao Tao; Xiang-Sheng Zhang; Yue Lu; Ling-Yun Wu; Yong-Yue Gao; Han Wang; Hai-Bin Dai; Yan Zhou; Zong Zhuang; Chun-Hua Hang; Wei Li (Molecular Neurobiology, 2021)

Effect of juvenile omni-benthivorous fish (Carassius carassius) disturbance on the efficiency of lanthanum-modified bentonite (LMB) for eutrophication control: a mesocosm study - Yanqing Han; Qisheng Li; Hu He; Jiao Gu; Zhaoshi Wu; Xiaolong Huang; Xiaojuan Zou; You Zhang; Kuanyi Li (Environmental Science and Pollution Research, 2021)

Effect of urban underlying surface on PM2.5 vertical distribution based on UAV in Xi’an, China - Kai Xin; Jingyuan Zhao; Xuan Ma; Li Han; Yanyu Liu; Jianxin Zhang; Yuejing Gao (Environmental Monitoring and Assessment, 2021)

Herbidospora solisilvae sp. nov., a novel cellulose-degrading actinobacterium isolated from forest soil - Mingying Yu; Rui Zhou; Jingjing Li; Liyuan Han; Han Wang; Siyu Zhang; Junwei Zhao; Xiangjing Wang; Jia Song; Wensheng Xiang (Antonie van Leeuwenhoek, 2021)

In vitro and In vivo Antibacterial Effects of Nisin Against Streptococcus suis - Haodan Zhu; Lixiao Han; Yanxiu Ni; Zhengyu Yu; Dandan Wang; Junming Zhou; Bin Li; Wei Zhang; Kongwang He (Probiotics and Antimicrobial Proteins, 2021)

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

The circular RNA circSlc7a11 promotes bone cancer pain pathogenesis in rats by modulating LLC-WRC 256 cell proliferation and apoptosis - Han-Wen Chen; Xiao-Xia Zhang; Zhu-Ding Peng; Zu-Min Xing; Yi-Wen Zhang; Ya-Lan Li (Molecular and Cellular Biochemistry, 2021)
Treatment of bone cancer pain (BCP) caused by bone metastasis in advanced cancers remains a challenge in clinical oncology, and the underlying mechanisms of BCP are poorly understood. This study aimed to investigate the pathogenic roles of circular RNAs (circRNAs) in regulating cancer cell proliferation and BCP development. Eight differentially expressed circRNAs in the rat spinal cord were validated by agarose gel electrophoresis and Sanger sequencing. Expression of circRNAs and mRNAs was detected by quantitative RT-PCR. MTS assay and flow cytometry were performed to analyze cell proliferation and apoptosis, respectively. Differentially expressed mRNA profiles were characterized by deep RNA sequencing, hierarchical clustering, and functional categorization. The interactions among circRNAs, microRNAs (miRNAs), and mRNAs were predicted using TargetScan. Additionally, western blot was performed to determine the protein levels of Pax8, Isg15, and Cxcl10. Multiple circRNAs were differentially expressed in the spinal cords of BCP model rats; of these, circSlc7a11 showed the greatest increase in expression. The overexpression of circSlc7a11 significantly promoted cell proliferation and repressed apoptosis of LLC-WRC 256 and UMR-106 cells, whereas circSlc7a11 silencing produced the opposite effects. Altered expression of circSlc7a11 also induced substantial changes in the mRNA expression profiles of LLC-WRC 256 cells; these changes were linked to multiple apoptotic processes and signaling pathways, such as the chemokine signaling pathway, and formed a complex circRNA/miRNA/mRNA network. Additionally, Pax8, Isg15, and Cxc110 protein level in LLC-WRC 256 cells was consistent with the mRNA results. The circRNA circSlc7a11 regulates rat BCP development by modulating LLC-WRC 256 cell proliferation and apoptosis through multiple-signaling mechanisms.

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

The Fe3O4-modified biochar reduces arsenic availability in soil and arsenic accumulation in indica rice (Oryza sativa L.) - Yao Yao; Hang Zhou; Xiu-Lan Yan; Xiao Yang; Kang-Wen Huang; Juan Liu; Li-Juan Li; Jing-Yi Zhang; Jiao-Feng Gu; Yaoyu Zhou; Bo-Han Liao (Environmental Science and Pollution Research, 2021)

Transformation of China’s urbanization and eco-environment dynamics: an insight with location-based population-weighted indicators - Lijian Han; Xiaoyan Zhang; Weiqi Zhou; Miaogen Shen; Yan Huang; Weifeng Li; Yuguo Qian (Environmental Science and Pollution Research, 2021)

Nitrogen Enrichment Reduces Nitrogen and Phosphorus Resorption Through Changes to Species Resorption and Plant Community Composition - Xiao-Tao Lü; Shuang-Li Hou; Sasha Reed; Jiang-Xia Yin; Yan-Yu Hu; Hai-Wei Wei; Zhi-Wei Zhang; Guo-Jiao Yang; Zhuo-Yi Liu; Xing-Guo Han (Ecosystems, 2021)

Marinobacter shengliensis subsp. alexandrii Subsp. Nov., Isolated from Cultivable Phycosphere Microbiota of Highly Toxic Dinoflagellate Alexandrium catenella LZT09 and Description of Marinobacter shengliensis Subsp. shengliensis Subsp. Nov - Xi Yang; Rong Xiang; Nurhezreen Md Iqbal; Yu-Han Duan; Xiao-Ai Zhang; Lei Wang; Lin-Zeng Yu; Jia-Zhou Li; Ming-Fei Sun; Qiao Yang; Chun-Tian Zheng; Shen-Quan Liao (Current Microbiology, 2021)

Aging and age‐related diseases: from mechanisms to therapeutic strategies - Zhe Li; Zhenkun Zhang; Yikun Ren; Yingying Wang; Jiarui Fang; Han Yue; Shanshan Ma; Fangxia Guan (Biogerontology, 2021)

Comprehensive Marine Observing Experiment Based on High-Altitude Large Unmanned Aerial Vehicle (South China Sea Experiment 2020 of the “Petrel Project”) - Xuefen Zhang; Liangxu Li; Rongkang Yang; Ran Guo; Xia Sun; Jianping Luo; Hongbin Chen; Daxin Liu; Kebing Tang; Wenwu Peng; Xiaodong Han; Qiyun Guo; et al. (Advances in Atmospheric Sciences, 2021)

Summer pruning improves the branch growth and tea quality of tea trees (Camellia sinensis) - Liping Zhang; Menghan Li; Xin Li; Peng Yan; Lan Zhang; Wenyan Han (Acta Physiologiae Plantarum, 2021)

EmhR is an indole‐sensing transcriptional regulator responsible for the indole‐induced antibiotic tolerance in Pseudomonas fluorescens - Jian‐Ting Han; Di‐Yin Li; Meng‐Yuan Zhang; Xiao‐Quan Yu; Xiang‐Xue Jia; Hang Xu; Xu Yan; Wen‐Juan Jia; Shaomin Niu; Megan L. Kempher; Xuanyu Tao; Yong‐Xing He (Environmental Microbiology, 2021)
Summary Indole is well known as an interspecies signalling molecule to modulate bacterial physiology; however, it is not clear how the indole signal is perceived and responded to by plant growth promoting rhizobacteria (PGPR) in the rhizosphere. Here, we demonstrated that indole enhanced the antibiotic tolerance of Pseudomonas fluorescens 2P24, a PGPR well known for its biocontrol capacity. Proteomic analysis revealed that indole influenced the expression of multiple genes including the emhABC operon encoding a major multidrug efflux pump. The expression of emhABC was regulated by a TetR‐family transcription factor EmhR, which was demonstrated to be an indole‐responsive regulator. Molecular dynamics simulation showed that indole allosterically affected the distance between the two DNA‐recognizing helices within the EmhR dimer, leading to diminished EmhR–DNA interaction. It was further revealed the EmhR ortholog in Pseudomonas syringae was also responsible for indole‐induced antibiotic tolerance, suggesting this EmhR‐dependent, indole‐induced antibiotic tolerance is likely to be conserved among Pseudomonas species. Taken together, our results elucidated the molecular mechanism of indole‐induced antibiotic tolerance in Pseudomonas species and had important implications on how rhizobacteria sense and respond to indole in the rhizosphere.

Rare taxa maintain the stability of crop mycobiomes and ecosystem functions - Chao Xiong; Ji‐Zheng He; Brajesh K. Singh; Yong‐Guan Zhu; Jun‐Tao Wang; Pei‐Pei Li; Qin‐Bing Zhang; Li‐Li Han; Ju‐Pei Shen; An‐Hui Ge; Chuan‐Fa Wu; Li‐Mei Zhang (Environmental Microbiology, 2021)
Summary Plants harbour highly diverse mycobiomes which sustain essential functions for host health and productivity. However, ecological processes that govern the plant–mycobiome assembly, interactions and their impact on ecosystem functions remain poorly known. Here we characterized the ecological role and community assembly of both abundant and rare fungal taxa along the soil–plant continuums (rhizosphere, phyllosphere and endosphere) in the maize–wheat/barley rotation system under different fertilization practices at two contrasting sites. Our results indicate that mycobiome assembly is shaped predominantly by compartment niche and host species rather than by environmental factors. Moreover, crop‐associated fungal communities are dominated by few abundant taxa mainly belonging to Sordariomycetes and Dothideomycetes, while the majority of diversity within mycobiomes are represented by rare taxa. For plant compartments, the abundant sub‐community is mainly determined by stochastic processes. In contrast, the rare sub‐community is more sensitive to host selection and mainly governed by deterministic processes. Furthermore, our results demonstrate that rare taxa play an important role in fungal co‐occurrence network and ecosystem functioning like crop yield and soil enzyme activities. These results significantly advance our understanding of crop mycobiome assembly and highlight the key role of rare taxa in sustaining the stability of crop mycobiomes and ecosystem functions.

Review of Huang-huai sheep, a new multiparous mutton sheep breed first identified in China - Kai Quan; Jun Li; Haoyuan Han; Hongfang Wei; Jinyan Zhao; HA Si; Xinji Zhang; Daojiang Zhang (Tropical Animal Health and Production, 2021)
Huang-huai sheep are a new multiparous mutton sheep breed that has been cultivated by domestic scientific research institutes, governments, and sheep farms in China. Huang-huai sheep were bred using Dorper sheep as a sire and Small-tailed Han sheep as a dam. The breeding of Huang-huai sheep started in 2003, and three stages have been carried out: crossbreeding innovation, fixation in a two-way-crossbred closed flock, and herd propagation. A pilot test of Huang-huai sheep was conducted on 6 sheep farms from 2017 to 2018, and hereditary properties and production performance were evaluated in 2019. Huang-huai sheep were identified on site by the National Livestock and Poultry Resources Committee of China in December 2019 and approved as a new multiparous mutton sheep breed in China. The genetic distance showed that Huang-huai sheep are most closely related to Dorper sheep, Luxi black-headed sheep, and Small-tailed Han sheep, but the genetic distances are subspecies (0.02–0.20) each other. The body weights of adult Huang-huai sheep are 98.1 ± 5.2 kg (♂) and 71.7 ± 3.5 kg (♀), and those of 6-month-old Huang-huai sheep are 58.50 ± 6.55 kg (♂) and 52.45 ± 5.67 kg (♀). The slaughter rates of 6-month-old sheep are 56.02 ± 1.25% (♂) and 53.19 ± 1.19% (♀). The estrus cycle of Huang-huai sheep is 19.32 ± 2.8 days, the first estrus cycle occurs at 168 ± 12 days, the annual lambing rate of ewes is 252.82% ± 10.69%, the survival rate of lambs is 95.79 ± 0.95%, and the number of weaned lambs per ewe per year is 2.38 ± 0.14. The growth performance, carcass quality, and reproductive performance of Huang-huai sheep have been improved, resulting in considerable economic and social benefits and broader market prospects. This breed represents a new multiparous mutton sheep breed adapted for industrial sheep farms in China.

Seismic wave equations in tight oil/gas sandstone media - Jinghuai Gao; Weimin Han; Yanbin He; Haixia Zhao; Hui Li; Yijie Zhang; Zongben Xu (Science China Earth Sciences, 2021)

Unraveling Physiological and Metabolomic Responses Involved in Phlox subulata L. Tolerance to Drought Stress - Yan Xiong; Yanting Qu; Hui Han; Fei Chen; Li Li; Huanwei Tang; Daidi Che; Xing Zhang (Plant Molecular Biology Reporter, 2021)

Prevalence of Depression or Depressive Symptoms in Patients with Narcolepsy: a Systematic Review and Meta-Analysis - Xiao Li; Larry D. Sanford; Qiang Zong; Ye Zhang; Lu Tan; Taomei Li; Rong Ren; Junying Zhou; Fang Han; Xiangdong Tang (Neuropsychology Review, 2021)

The cellulose synthase (CesA) gene family in four Gossypium species: phylogenetics, sequence variation and gene expression in relation to fiber quality in Upland cotton - Sujun Zhang; Zhenxing Jiang; Jie Chen; Zongfu Han; Jina Chi; Xihua Li; Jiwen Yu; Chaozhu Xing; Mingzhou Song; Jianyong Wu; Feng Liu; Xiangyun Zhang; et al. (Molecular Genetics and Genomics, 2021)

Downregulated hypoxia-inducible factor 1α improves myoblast differentiation under hypoxic condition in mouse genioglossus - Yun Lu; Jiaqi Mao; Xinxin Han; Weihua Zhang; Yuanyuan Li; Yuehua Liu; Qiang Li (Molecular and Cellular Biochemistry, 2021)

GINS2 was regulated by lncRNA XIST/miR-23a-3p to mediate proliferation and apoptosis in A375 cells - Yu-Qin Hao; Ke-Wei Liu; Xin Zhang; Shu-Xia Kang; Kun Zhang; Wurihan Han; Li Li; Zhe-Hai Li (Molecular and Cellular Biochemistry, 2021)

Plateau lake ecological response to environmental change during the last 60 years: a case study from freshwater Lake Yangzong, SW China - Han Wu; Hucai Zhang; Yanling Li; Fengqin Chang; Lizeng Duan; Xiaonan Zhang; Wei Peng; Qi Liu; Fengwen Liu; Yun Zhang (Journal of Soils and Sediments, 2021)

Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling - Li Zhang; Lu Wang; Han Xiao; Hui Gan; Hui Chen; Shuyue Zheng; Dan Jian; Xuan Zhai; Ning Jiang; Zhao Jing; Ping Liang (Journal of Molecular Medicine, 2021)

Ultra-Fast Computation of Excited-States Spectra for Large Systems: Ultraviolet and Fluorescence Spectra of Proteins - Yonggang Liu; Jianjie Xu; Li Han; Qiangqiang Liu; Yunfan Yang; Zeren Li; Zhongyuan Lu; Hang Zhang; Tengxiao Guo; Qiao Liu (Interdisciplinary Sciences: Computational Life Sciences, 2021)

Fractionation of carbon isotopes of dissolved organic matter adsorbed to goethite in the presence of arsenic to study the origin of DOM in groundwater - Yanan Zhang; Yiqun Gan; Kai Yu; Li Han (Environmental Geochemistry and Health, 2021)

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

The development and application of China national landslide database and information system - Bin Tong; Yuan Li; Xudong Yang; Chunrong Yin; Xueyan Qu; Hao Fang; Bing Han; Yanling Zhang (Arabian Journal of Geosciences, 2021)

Characterization on the physiological traits of plants and yield formation capacity upon water- and N-saving conditions in wheat (T. aestivum L.) - Pingping Du; Liguo Guo; Lili Si; Le Han; Shuang Zhang; Fangfang Li; Kai Xiao (Acta Physiologiae Plantarum, 2021)

Transcriptional and post-transcriptional regulation of the miR171-LaSCL6 module during somatic embryogenesis in Larix kaempferi - Qiao-Lu Zang; Yao Zhang; Su-Ying Han; Wan-Feng Li; Li-Wang Qi (Trees, 2021)
Key message Expression analysis of Larix kaempferi mature miR171s and their primary transcripts and target gene LaSCL6 during somatic embryogenesis revealed the transcriptional and post-transcriptional regulation of the miR171- LaSCL6 module. Abstract Somatic embryogenesis provides a useful experimental system for studying the regulatory mechanisms of plant development. The level and activity of microRNA171 (miR171) fluctuate during somatic embryogenesis in Larix kaempferi , but the underlying mechanisms are still unclear. Here, in L. kaempferi we identified five members of the miR171 family, which cleave LaSCL6 mRNA at different sites. In addition, we improved the method of measuring miRNA activity in a more direct way. Furthermore, we measured the expression patterns of mature miR171s and their primary transcripts during somatic embryogenesis in L. kaempferi and found that their patterns differed, indicating that the transcription of MIR171 genes and the subsequent cleavage of their intermediate products are regulated. Taken together, our findings not only offer a means to study the regulation of miRNA activity, but also provide further insight into the regulation of L . kaempferi somatic embryogenesis by miR171- LaSCL6 .

Pathological matrix stiffness promotes cardiac fibroblast differentiation through the POU2F1 signaling pathway - Mingzhe Li; Jimin Wu; Guomin Hu; Yao Song; Jing Shen; Junzhou Xin; Zijian Li; Wei Liu; Erdan Dong; Ming Xu; Youyi Zhang; Han Xiao (Science China Life Sciences, 2021)

Sex Differences in Electrophysiological Properties of Mouse Medial Preoptic Area Neurons Revealed by In Vitro Whole-cell Recordings - Wen Zhang; Shuai-shuai Li; Ying Han; Xiao-Hong Xu (Neuroscience Bulletin, 2021)

TAK1 is involved in sodium L-lactate-stimulated p38 signaling and promotes apoptosis - Qingen Da; Zilong Yan; Zhangfu Li; Zhen Han; Mingming Ren; Lei Huang; Xiaowei Zhang; Jikui Liu; Tao Wang (Molecular and Cellular Biochemistry, 2021)

The application of an absorbent-amended microalgal-bacterial system for enhancing hydrothermal liquefaction wastewater treatment and resource recovery - Ting Han; Mengzi Wang; Haifeng Lu; Yuanhui Zhang; Guangming Zhang; Baoming Li; Wei Cao (Journal of Applied Phycology, 2021)

The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish - Si-Lan Han; Yan Liu; Samwel M. Limbu; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2021)

Cytogenetic analysis of interspecific hybridization in oil-tea (Camellia oleifera) - Yanmin Li; Tianwen Ye; Chunxia Han; Zhihua Ye; Jian Zhang; Shixin Xiao; Deyi Yuan (Euphytica, 2021)

Association between selected urinary heavy metals and asthma in adults: a retrospective cross-sectional study of the US National Health and Nutrition Examination Survey - Xiuzhu Li; Yun Fan; Yan Zhang; Xiaomin Huang; Zhenyao Huang; Mingming Yu; Qiaoqiao Xu; Xiumei Han; Chuncheng Lu; Xinru Wang (Environmental Science and Pollution Research, 2021)

Laboratory investigation of the temperature influence on the mechanical properties and fracture crack distribution of rock under uniaxial compression test - Weijing Xiao; Dongming Zhang; Han Yang; Xiaoming Li; Maolin Ye; Shujian Li (Bulletin of Engineering Geology and the Environment, 2021)

Simultaneously decreased temporal variability and enhanced variability-strength coupling of emotional network connectivities are related to positive symptoms in patients with schizophrenia - Yanjia Deng; Shuguang Han; Dongliang Cheng; Hui Li; Bin Zhang; Youyong Kong; Yong Lin; Yingjia Li; Ge Wen; Kai Liu (Brain Imaging and Behavior, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

Altered resting-state networks may explain the executive impairment in young health immigrants into high-altitude area - Xiaoming Chen; Jian Liu; Jiye Wang; Zhenlong Xin; Qian Zhang; Wenbin Zhang; Yibin Xi; Yuanqiang Zhu; Chen Li; Jiaming Li; Yuedong Han; Jie Liu; et al. (Brain Imaging and Behavior, 2021)

Quantitatively determine the dominant driving factors of the spatial—temporal changes of vegetation NPP in the Hengduan Mountain area during 2000–2015 - Shu-ting Chen; Bing Guo; Rui Zhang; Wen-qian Zang; Cui-xia Wei; Hong-wei Wu; Xiao Yang; Xiao-yan Zhen; Xing Li; Da-fu Zhang; Bao-min Han; Hai-ling Zhang (Journal of Mountain Science, 2021)

Transcriptome reveals genes involving in black skin color formation of ducks - Lei Wang; Hehe Liu; Bo Hu; Jiwei Hu; Hengyong Xu; Hua He; Chunchun Han; Bo Kang; Lili Bai; Rongping Zhang; Jiwen Wang; Shengqiang Hu; et al. (Genes & Genomics, 2021)

Sodium alginate/collagen hydrogel loaded with human umbilical cord mesenchymal stem cells promotes wound healing and skin remodeling - Zhenkun Zhang; Zhe Li; Ya Li; Yingying Wang; Minghao Yao; Kun Zhang; Zhenyu Chen; Han Yue; Jijing Shi; Fangxia Guan; Shanshan Ma (Cell and Tissue Research, 2021)

The impact of global dimming on crop yields is determined by the source–sink imbalance of carbon during grain filling - Liping Shao; Zijuan Liu; Haozheng Li; Yaling Zhang; Mingming Dong; Xuanhe Guo; Han Zhang; Baowei Huang; Rongbing Ni; Gang Li; Chuang Cai; Weiping Chen; et al. (Global Change Biology, 2021)
Global dimming reduces incident global radiation but increases the fraction of diffuse radiation, and thus affects crop yields; however, the underlying mechanisms of such an effect have not been revealed. We hypothesized that crop source–sink imbalance of either carbon (C) or nitrogen (N) during grain filling is a key factor underlying the effect of global dimming on yields. We presented a practical framework to assess both C and N source–sink relationships, using data of biomass and N accumulation from periodical sampling conducted in field experiments for wheat and rice from 2013 to 2016. We found a fertilization effect of the increased diffuse radiation fraction under global dimming, which alleviated the negative impact of decreased global radiation on source supply and sink growth, but the source supply and sink growth were still decreased by dimming, for both C and N. In wheat, the C source supply decreased more than the C sink demand, and as a result, crops remobilized more pre‐heading C reserves, in response to dimming. However, these responses were converse in rice, which presumably stemmed from the more increment in radiation use efficiency and the more limited sink size in rice than wheat. The global dimming affected source supply and sink growth of C more significantly than that of N. Therefore, yields in both crops were dependent more on the source–sink imbalance of C than that of N during grain filling. Our revealed source–sink relationships, and their differences and similarities between wheat and rice, provide a basis for designing strategies to alleviate the impact of global dimming on crop productivity.

Diversity and potential biogeochemical impacts of viruses in bulk and rhizosphere soils - Li Bi; Dan‐Ting Yu; Shuai Du; Li‐Mei Zhang; Li‐Yu Zhang; Chuan‐Fa Wu; Chao Xiong; Li‐Li Han; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Viruses can affect microbial dynamics, metabolism and biogeochemical cycles in aquatic ecosystems. However, viral diversity and functions in agricultural soils are poorly known, especially in the rhizosphere. We used virome analysis of eight rhizosphere and bulk soils to study viral diversity and potential biogeochemical impacts in an agro‐ecosystem. The order Caudovirales was the predominant viral type in agricultural soils, with Siphoviridae being the most abundant family. Phylogenetic analysis of the terminase large subunit of Caudovirales identified high viral diversity and three novel groups. Viral community composition differed significantly between bulk and rhizosphere soils. Soil pH was the main environmental driver of the viral community structure. Remarkably, abundant auxiliary carbohydrate‐active enzyme (CAZyme) genes were detected in viromes, including glycoside hydrolases, carbohydrate esterases and carbohydrate‐binding modules. These results demonstrate that virus‐encoded putative auxiliary metabolic genes or metabolic genes that may change bacterial metabolism and indirectly contribute to biogeochemical cycling, especially carbon cycling, in agricultural soil.

Hydrodynamic Model of Diver–DPV Coupled Multi-Body and Its Underwater Cruising Numerical Simulation - Hansheng Li; Fenglei Han; Haitao Zhu; Jiawei Zhang; Weipeng Zhang; Yuliang Wu (Journal of Marine Science and Engineering, 2021)
Diver propulsion vehicles (hereinafter referred to as DPV) are a kind of small vehicle with underwater high-speed used by divers, who are able to grasp or ride on, and operate the volume switch to change the speed. Different from unmanned underwater vehicles (UUVs), the interference caused by diver’s posture changing is a unique problem. In this paper, a Diver–DPV multi-body coupling hydrodynamic model considering rigid body dynamics and fluid disturbance is established by analyzing the existing DPV related equipment. The numerical simulation of multi-body articulated motion is realized by using Star-CCM+ overlapping grid and DFBI 6-DOF body motion method. Five cases of DPVs underwater cruising in a straight-line when restraining diver movement is simulated, and five cases with free diver movement are simulated too. Finally, the influence of the diver’s posture changing on the cruising speed resistance is analyzed, and the motion equation including the disturbance is solved. The final conclusion is that, the disturbance is favorable at high speed, which can reduce the cruising resistance, and unfavorable at low speed, which increases the cruising resistance. The friction resistance Ff always accounts for the main part in all speed cases.

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Partial recovery of disturbed V-J pairing profiles of T-cell receptor in people living with HIV receiving long-term antiretroviral therapy - Guoli Li; Jiarui Li; Henghui Zhang; Yu Zhang; Di Liu; Yu Hao; Junyan Han; Juan Du; Liuluan Zhu; Yongqin Zeng; Bei Li; Rui Li; et al. (Science China Life Sciences, 2021)