All-in-one additive enables defect passivated, crystallization modulated and moisture resisted perovskite films toward efficient solar cells - Chuanming Tian; Yu Zhao; Xuefei Han; Bin Li; Yichuan Rui; Hao Xiong; Yu Qiu; Wei An; Kerui Li; Chengyi Hou; Yaogang Li; Hongzhi Wang; et al. (Chemical Engineering Journal, 2023)

Inspired by philosophizing of “point to area”: Ion pre-intercalation induces the reconstitution of interlayer environment of MXene for lithium storage - Miao Liu; Xin Qu; Yixuan Wang; Yukai Zhang; Cuimei Zhao; Bo Liu; Xiangxin Xue; Junkai Zhang; Zhao Wang; Jiaming Li; Wenjuan Han; Shichong Xu; et al. (Chemical Engineering Journal, 2023)

Fabrication and Characterization of a MnO2/Ti3C2Tx Based Gas Sensor for Highly Sensitive and Selective Detection of Lung Cancer Marker Hexanal - Yu Yao; Zhanhong Li; Yutong Han; Lili Xie; Xueling Zhao; Zhigang Zhu (Chemical Engineering Journal, 2023)

Passivation of positively charged cationic defects in perovskite with nitrogen-donor crown ether enabling efficient perovskite solar cells - Yuxuan Yang; Tao Zhao; Ming-Hua Li; Xiaoxue Wu; Mingyue Han; Shih-Chi Yang; Qiaoling Xu; Lede Xian; Xiang Chi; Ning-Jiu Zhao; Hong Cui; Sihan Li; et al. (Chemical Engineering Journal, 2023)

Reaction gas-induced partial exsolution of Pd from PdCeMnO for methane combustion - Han Zhao; Yuanlong Tan; Lin Li; Yang Su; Aiqin Wang; Xiao Yan Liu; Tao Zhang (Chemical Engineering Journal, 2023)

Defect-adaptive Stem-cell-microcarrier Construct Promotes Tissue Repair in Rabbits with Knee Cartilage Defects - Zhidong Zhao; Yuxing Wang; Bofeng Yin; Xiaotong Li; Ruicong Hao; Zhiling Li; Peilin Li; Mengyue Han; Li Ding; Zhongli Li; Heng Zhu (Stem Cell Reviews and Reports, 2023)

Seasonal precipitation and soil microbial community influence plant growth response to warming and N addition in a desert steppe - Yi Zhu; Kailiang Yu; Qian Wu; Xu Cheng; Zhiguo Li; Zhongwu Wang; Mengli Zhao; Andreas Wilkes; Ton Bisselling; Guodong Han; Haiyan Ren (Plant and Soil, 2023)

Interactive Effects of Iron and Photoperiods on Tomato Plant Growth and Fruit Quality - Yi Zhang; Yi Liang; Jing Han; Xiaohui Hu; Xiaojing Li; Hailiang Zhao; Longqiang Bai; Yu Shi; Golam Jalal Ahammed (Journal of Plant Growth Regulation, 2023)

Sound speed profiles in high spatiotemporal resolution using multigrid three-dimensional variational method: a coastal experiment off northern Shandong Peninsula - Guangchao Hou; Jingsheng Zhai; Qi Shao; Yanling Zhao; Wei Li; Guijun Han; Kangzhuang Liang (Journal of Oceanology and Limnology, 2023)

A new global TEC empirical model based on fusing multi-source data - Jiandi Feng; Ting Zhang; Wang Li; Zhenzhen Zhao; Baomin Han; Kaixin Wang (GPS Solutions, 2023)

Sensitive biosensors based on topological insulator Bi2Se3 and peptide - Yujiu Jiang; Peng Zhu; Jinge Zhao; Shanshan Li; Yetong Wu; Xiaolu Xiong; Xu Zhang; Yuxiang Liu; Jiangyue Bai; Zihang Wang; Shiqi Xu; Minxuan Wang; et al. (Analytica Chimica Acta, 2023)

A sustainable approach to narrowing the summer maize yield gap experienced by smallholders in the North China Plain - Hongzhang Wang; Hao Ren; Lihua Zhang; Yali Zhao; Yuee Liu; Qijin He; Geng Li; Kun Han; Jiwang Zhang; Bin Zhao; Baizhao Ren; Peng Liu (Agricultural Systems, 2023)

Trifolium repens and biochar addition affecting soil nutrients and bacteria community - Pingnan Zhao; Jie Yu; Xiaoyuan Zhang; Zhixing Ren; Ming Li; Song Han (Environmental Science and Pollution Research, 2022)

The landscape of aging - Yusheng Cai; Wei Song; Jiaming Li; Ying Jing; Chuqian Liang; Liyuan Zhang; Xia Zhang; Wenhui Zhang; Beibei Liu; Yongpan An; Jingyi Li; Baixue Tang; et al. (Science China Life Sciences, 2022)

Acute Toxicity of a Novel anti-fouling Material Additive DCOIT to Marine Chlorella sp - Jin-Chuang Ru; Xue-Li Zhao; Zhi-Han Cao; Cheng-Zhuang Chen; Ping Li; Zhi-Hua Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Immunogenicity and protective efficacy of a DNA vaccine inducing optimal expression of the SARS-CoV-2 S gene in hACE2 mice - Zhuo-xin Li; Sheng Feng; He Zhang; Xin-yu Zhuang; Chao Shang; Shi-yu Sun; Ji-cheng Han; Yu-biao Xie; Jin-yong Zhang; Wei Wang; Cheng-hui Li; Guan-yu Zhao; et al. (Archives of Virology, 2022)

Effects of Dietary Tannic Acid on Growth, Digestion, Immunity and Resistance to Ammonia Stress, and Intestinal Microbial Community in Pacific White Shrimp (Litopenaeus vannamei) - Han Gong; Zhen Qin; Zhao Chen; Jitao Li; Zhiqiang Chang; Jian Li; Ping Chen (Fishes, 2022)
Tannic acid (TA) has great potential as a new feed additive. In this study, we investigated the effects of dietary TA on growth, digestion, nonspecific immunity, and resistance to ammonia stress and intestinal microbiota in Litopenaeus vannamei. The shrimp were fed diets containing different levels of TA: 0 mg/kg (TA-0), 200 mg/kg (TA-200), 400 mg/kg (TA-400), and 800 mg/kg (TA-800) for 56 days, followed by acute ammonia stress for 48 h. The results showed that dietary TA increased the survival rate of the TA-800 group. Dietary TA could improve the morphology of the hepatopancreas and intestinal tissues. After feeding different levels of TA for 56 days, the activities of amylase (AMS) and trypsin (Tryp) were increased, but the activity of lipase (LPS) was decreased. The activities of T-AOC, SOD, and PPO were higher in the hepatopancreas of the three TA treatment groups (p

Preparation of Hypercrosslinked Polymer-Based Sponge and its Application for the Removal of Non-Steroidal Anti-Inflammatory Drugs in Water Samples - Pengzhao Han; Kai Hu; Lixin Li; Yuanqing Zhao; Cheng Yang; Xiaobing Liu; Shusheng Zhang; Yanjie Huang (Water, Air, & Soil Pollution, 2022)

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression - Qin Jin; Xiaoyu Yang; Shixue Gou; Xiaoyi Liu; Zhenpeng Zhuang; Yanhui Liang; Hui Shi; Jiayuan Huang; Han Wu; Yu Zhao; Zhen Ouyang; Quanjun Zhang; et al. (Science China Life Sciences, 2022)

High levels of serum IL-10 indicate disease progression, extramedullary involvement, and poor prognosis in multiple myeloma - Xiaoyan Yue; Linlin Huang; Yang Yang; Yi Zhao; Donghua He; Xiaoyan Han; Gaofeng Zheng; Yi Li; Enfan Zhang; Zhen Cai; Xin Huang; Jingsong He (Journal of Zhejiang University-SCIENCE B, 2022)

Coupling coordination degree and driving factors of new-type urbanization and low-carbon development in the Yangtze River Delta: based on nighttime light data - Dongliang Li; Linjian Cao; Zhanhang Zhou; Kuokuo Zhao; Zhinian Du; Kaiqiang Han (Environmental Science and Pollution Research, 2022)

Associations between short-term exposure to ambient PM2.5 and incident cases of cerebrovascular disease in Yantai, China - Junyan Liu; Maobo Wang; Yang Zhao; Haotian Chen; Haiyun Liu; Baoshun Yang; Haifeng Shan; Hongyu Li; Yukun Shi; Luyang Wang; Guangcheng Wang; Chunlei Han (Environmental Science and Pollution Research, 2022)

Improving the bioavailability and bioactivity of garlic bioactive compounds via nanotechnology - Xiaoming Lu; Chaofan Wang; Meng Zhao; Jinxiang Wu; Zhonglu Niu; Xueli Zhang; Jesus Simal-Gandara; Ipek Süntar; Seid Mahdi Jafari; Xuguang Qiao; Xiaozhen Tang; Zhenlin Han; et al. (Critical Reviews in Food Science and Nutrition, 2022)

cPKCγ Deficiency Exacerbates Autophagy Impairment and Hyperphosphorylated Tau Buildup through the AMPK/mTOR Pathway in Mice with Type 1 Diabetes Mellitus - Jiayin Zheng; Yue Wang; Yue Liu; Song Han; Ying Zhang; Yanlin Luo; Yi Yan; Junfa Li; Li Zhao (Neuroscience Bulletin, 2022)

Facial emotion perception abilities are related to grey matter volume in the culmen of cerebellum anterior lobe in drug-naïve patients with first-episode schizophrenia - Xiaoxin Zhao; Jingjing Yao; Yiding Lv; Xinyue Zhang; Chongyang Han; Lijun Chen; Fangfang Ren; Qun Zhou; Zhuma Jin; Yuan Li; Yasong Du; Yuxiu Sui (Brain Imaging and Behavior, 2022)

Protective Effects of Sepia Ink Melanin on Hepatic Tissue in Streptozotocin-Induced Diabetic Mice - Xiaopeng Wang; Meng Han; Hui Dong; Yun Zhao; Weiwei Song; Chunlin Wang; Changkao Mu; Ronghua Li (Journal of Ocean University of China, 2022)

Development of 45 SNP markers in Triplophysa hsutschouensis based on RAD sequencing - Ya Liu; Jiansheng Lai; Zhongmeng Zhao; Hongyu Ke; Han Zhao; Yeyu Chen; Xiaoyun Wu; Qiang Li (Conservation Genetics Resources, 2022)

Waveform and resistivity data fusion imaging method based on the reflection coefficient - Maoxin Su; Min Han; Yiguo Xue; Ying Zhao; Peng Wang; Guangkun Li (Acta Geophysica, 2022)

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Fried-food consumption and risk of overweight/obesity, type 2 diabetes mellitus, and hypertension in adults: a meta-analysis of observational studies - Pei Qin; Dechen Liu; Xiaoyan Wu; Yunhong Zeng; Xizhuo Sun; Yanyan Zhang; Yang Li; Yuying Wu; Minghui Han; Ranran Qie; Shengbing Huang; Yang Zhao; et al. (Critical Reviews in Food Science and Nutrition, 2022)

Sensitive time-resolved fluoroimmunoassay for the quantitative detection of okadaic acid - Yuan Qin; Jiayu Li; Jiani Kuang; Sicheng Shen; Jingwen Jiang; Zhi Zhang; Chenhao Zhao; Xiumei Zhou; Biao Huang; Bingnan Han (Frontiers in Marine Science, 2022)
Okadaic acid (OA) is a biotoxin from marine microalgae and widely present in shellfish, which severely affects the seafood safety. Therefore, it is essential to establish a highly sensitive OA analysis and detection method. In this study, a new type of immunoassay technology was established on the basis of the competition method using time-resolved fluoroimmunoassay (TRFIA). OA-bovine serum albumin (OA-BSA) coated on a 96-well plate competes with OA standard or samples to bind OA antibodies. A rare-earth ion-labeled secondary antibody, which fluoresces strongly under the effect of the enhancement solution, was then added as a tracer for detection. The established linear range of OA detected by TRFIA was 2.49 × 10 -3 – 50 ng/ml, and the limit of detection was 2.49 × 10 -3 ng/ml. The average coefficients of variation from intra-assay and inter-assay batches were 3.34% and 5.87%, respectively, and the recovery rate was 93.04%–111.66%. The OA in shellfish samples was determined by TRFIA and high-performance liquid chromatography (HPLC), and the results showed a good correlation. This study established a TRFIA to detect OA, which has the characteristics of simplicity, sensitivity, precision, and high accuracy, far exceeding the EU or the US standards for the detection of shellfish toxins. It is expected to make proper contribution in marine biotoxin detection.

PTEN-induced kinase 1 enhances the reparative effects of bone marrow mesenchymal stromal cells on mice with renal ischaemia/reperfusion-induced acute kidney injury - Chenyu Lin; Wen Chen; Yong Han; Yujie Sun; Xiaoqiong Zhao; Yuan Yue; Binyu Li; Wenmei Fan; Tao Zhang; Li Xiao (Human Cell, 2022)
Acute kidney injury (AKI) is a common severe acute syndrome caused by multiple factors and is characterized by a rapid decline in renal function during a short period. Bone marrow mesenchymal stromal cells (BMSCs) are effective in treating AKI. However, the mechanism of their beneficial effects remains unclear. PTEN-induced kinase 1 (PINK1) may play an important role in kidney tissue repair. In this study, we explored the effect of PINK1 overexpression on enhancing BMSC-mediated repair of AKI. In this study, ischaemia/reperfusion-induced AKI (IRI-AKI) in mice and a hypoxia-reoxygenation model in cells were established, and the indices were examined by pathology and immunology experiments. After ischaemia/reperfusion, PINK1 overexpression reduced apoptosis in injured kidney tissue cell, decreased T lymphocyte infiltration, increased macrophage infiltration, and alleviated the inflammatory response. PINK1 relieved the stress response of BMSCs and renal tubular epithelial cells (RTECs), reduced apoptosis, altered the release of inflammatory factors, and reduced the proliferation of peripheral blood mononuclear cells (PBMCs). In conclusion, BMSCs and RTECs undergo stress responses in response to hypoxia, inflammation and other conditions, and overexpressing PINK1 in BMSCs could enhance their ability to resist these stress reactions. Furthermore, PINK1 overexpression can regulate the distribution of immune cells and improve the inflammatory response. The regulation of mitochondrial autophagy during IRI-AKI maintains mitochondrial homeostasis and protects renal function. The results of this study provide new strategies and experimental evidence for BMSC-mediated repair of IRI-AKI.

The brassinosteroid biosynthesis gene TaD11-2A controls grain size and its elite haplotype improves wheat grain yields - Huiyuan Xu; Han Sun; Jiajin Dong; Chengxue Ma; Jingxue Li; Zhuochun Li; Yihuan Wang; Junqi Ji; Xinrong Hu; Meihui Wu; Chunhua Zhao; Ran Qin; et al. (Theoretical and Applied Genetics, 2022)

High-precision potassium isotope analysis using the Nu Sapphire collision cell (CC)-MC-ICP-MS - Wenjun Li; Mengmeng Cui; Qiqi Pan; Jing Wang; Bingyu Gao; Shanke Liu; Meng Yuan; Benxun Su; Ye Zhao; Fang-Zhen Teng; Guilin Han (Science China Earth Sciences, 2022)

P2X7/P2X4 Receptors Mediate Proliferation and Migration of Retinal Microglia in Experimental Glaucoma in Mice - Meng-Xi Xu; Guo-Li Zhao; Xin Hu; Han Zhou; Shu-Ying Li; Fang Li; Yanying Miao; Bo Lei; Zhongfeng Wang (Neuroscience Bulletin, 2022)

Safrole oxide induced 5-HT neuron-like cell differentiation of bone marrow mesenchymal stem cells by elevating G9a - Xianjing Han; Yanchun Zhao; Chunhui Sun; Kunlun Li; Baoxiang Zhao; Junying Miao; Le Su (In Vitro Cellular & Developmental Biology - Animal, 2022)

Integrated analysis of the miRNA and mRNA expression profiles in Leiocassis longirostris at gonadal maturation - Han Zhao; Lu Zhang; Qiang Li; Zhongmeng Zhao; Yuanliang Duan; Zhipeng Huang; Hongyu Ke; Chao Liu; Huadong Li; Lu Liu; Jun Du; Zhen Wei; et al. (Functional & Integrative Genomics, 2022)

Transcriptome Profiling of Duodenum Reveals the Importance of Boron Supplementation in Modulating Immune Activities in Rats - Chunfang Zhao; Yujiao Han; Chenfang Wang; Man Ren; Qianqian Hu; Youfang Gu; Pengfei Ye; Shenghe Li; Erhui Jin (Biological Trace Element Research, 2022)

Enhancing or inhibiting apoptosis? The effects of ucMSC-Ex in the treatment of different degrees of traumatic pancreatitis - Zhao Zhirong; Han Li; He Yiqun; He Chunyang; Zhou Lichen; Tan Zhen; Wang Tao; Dai Ruiwu (Apoptosis, 2022)

Visible Particle Identification Using Raman Spectroscopy and Machine Learning - Han Sheng; Yinping Zhao; Xiangan Long; Liwen Chen; Bei Li; Yiyan Fei; Lan Mi; Jiong Ma (AAPS PharmSciTech, 2022)

Iron loss of paddy soil in China and its environmental implications - Liumei Chen; Dongbo Zhao; Guangzhong Han; Fei Yang; Zitong Gong; Xiaodong Song; Decheng Li; Ganlin Zhang (Science China Earth Sciences, 2022)

Diminished miR-374c-5p negatively regulates IL (interleukin)-6 in unexplained recurrent spontaneous abortion - Lin Zhao; Li Han; Guozhen Hei; Ran Wei; Zhen Zhang; Xiaoxiao Zhu; Qiang Guo; Chu Chu; Xiaoxiao Fu; Ke Xu; Xia Li (Journal of Molecular Medicine, 2022)

Identification of a major stable QTL for spikelet number in wheat (Triticum aestivum L.) and its genetic effects analysis on yield-related traits - Mingsu Cao; Jizi Dong; Hao Wang; Yibiao Cai; Tianhang Ma; Xiaohan Zhou; Jingguo Xiao; Shihui Li; Linqu Chen; Huiyuan Xu; Chunhua Zhao; Yongzhen Wu; et al. (Euphytica, 2022)

Brevibacillus dissolubilis sp. nov., Isolated from Fresh Water - Wei Li; Zhao-Xuan Wang; Fu Ma; Zhi-Da Zi; Han-Yi Chen; De Zhou; Jie Lv (Current Microbiology, 2022)

Aberrant topological organization and age-related differences in the human connectome in subjective cognitive decline by using regional morphology from magnetic resonance imaging - Zhenrong Fu; Mingyan Zhao; Yirong He; Xuetong Wang; Xin Li; Guixia Kang; Ying Han; Shuyu Li (Brain Structure and Function, 2022)

A study on the infection status and transmission of avian leukosis virus subgroup J in Hy-line brown roosters - Fanfeng Meng; Qiuchen Li; Rui Han; Guanlong Xu; Xintao Gao; Fubing Luo; Guangnian Shen; Xiaodong Liu; Zhifang Zhang; Peng Zhao; Guozhong Zhang (Archives of Virology, 2022)

Molecular Cloning of Heat Shock Protein 60 (SpHSP60) from Schizothorax prenanti and the Gene Expressions of Four SpHSPs during Lipopolysaccharide (LPS) Infection - Jianlu Zhang; Jiqin Huang; Cheng Fang; Wanchun Li; Hu Zhao; Fei Kong; Han Zhang; Hongxing Zhang; Qijun Wang (Fishes, 2022)
Heat shock proteins (HSPs) play a key role in anti-stress and immune processes and are associated with autoimmune diseases. In order to explore the immunological role of HSPs from Schizothorax prenanti (S. prenanti), SpHSP60 was cloned for the first time in this study, and the gene expressions of SpHSP27, SpHSP60, SpHSP70 and SpHSP90 in the hepatopancreas, head kidney, hindgut and spleen were analyzed by quantitative real-time PCR (qPCR) after treatment with lipopolysaccharide (LPS). The open reading frame of the SpHSP60 gene (GenBank accession number ON245159) is 1728 bp. It encodes a protein of 575 amino acids. Its C-terminus is a highly conserved and repeated glycine sequence, which is an important cofactor in ATP binding. Compared with the control group, most of the SpHSPs were significantly upregulated in the tissues examined at 12 or 24 h after LPS challenge. The most abundant expression of SpHSP70 was found in the head kidney at 24 h after LPS injection, followed by SpHSP27 in the spleen at 24 h; both of these SpHSPs displayed strong expression under the LPS stresses, about 20–70 fold more than that of SpHSP60 and SpHSP90. The temporal expression patterns of the four SpHSP genes were different in the four tissues examined. Taken together, the results suggest that SpHSP27, SpHSP60, SpHSP70 and SpHSP90 participate in innate immunity stimulated by LPS, and the response intensity of the SpHSPs was organ-specific, indicating they could provide early warning information against bacterial infection. The findings in our study will contribute to better understanding the biological processes and important roles of SpHSPs involved in defending against pathogenic bacterial challenge.

Effects of long-term exposure of norfloxacin on the HPG and HPT axes in juvenile common carp - Si-Qi Zhang; Xue-Li Zhao; Shu-Wen He; Shao-Ying Xing; Zhi-Han Cao; Ping Li; Zhi-Hua Li (Environmental Science and Pollution Research, 2022)

Deep learning–based stochastic modelling and uncertainty analysis of fault networks - Shuai Han; Heng Li; Mingchao Li; Jiawen Zhang; Runhao Guo; Jie Ma; Wenchao Zhao (Bulletin of Engineering Geology and the Environment, 2022)

DNA damage accumulation in aging brain and its links to Alzheimer’s disease progression - Han Zhao; Shiyao Wang; Xu Li (Genome Instability & Disease, 2022)

Isolation and characterization of 45 SNP markers in Triplophysa tenuis - Ya Liu; Yeyu Chen; Jiansheng Lai; Hongyu Ke; Zhongmeng Zhao; Han Zhao; Xiaoyun Wu; Jian Zhou; Qiang Li (Conservation Genetics Resources, 2022)

Toxic encephalopathy induced by radix Sophorae tonkinensis - Xue-Lin Li; Hao-Tian Zhao; Jinming Han; Zhong-Rui Yan; Hai-Yang Wang (Acta Neurologica Belgica, 2022)

Tea Polyphenols Improve Down-Regulation of Mitochondrial Functional Gene Expression Induced by Bisphenol A in Zebrafish Ovaries - Xiaoxin Dai; Lijun Qiu; Han Zhang; Chunying Xu; Bo Zhao; Yang Gao; Haidong Li; Yi Mu; Zhangjie Chu (Frontiers in Marine Science, 2022)
The plasticizer bisphenol A, a typical endocrine disrupting chemical, is widely present in the environment. Previous studies demonstrated that exposure to bisphenol A can cause reproductive toxicity, abnormal fertilization, and infertility. However, the mechanisms of low-concentration bisphenol A on the reproductive system and treatment measures have not been fully determined. In this study, we explored the transcriptomic profiles of female zebrafish ovaries. The transcriptomic data revealed that mitochondrial NADH dehydrogenase (mt-Nd) genes were significantly decreased in the bisphenol A-exposed group, while the co-administration of tea polyphenols remarkably elevated the expression of mt-Nd genes. To further explore the expression pattern of the mt-Nd, we analyzed the expression of six mt-Nd genes on different days by qRT-PCR in control, bisphenol A-exposed, and bisphenol A-tea polyphenols ovaries. Here, we found that 0.1 mg/L bisphenol A exposure adversely affects the mitochondrial respiratory chain in ovaries and may lead to reproductive disorders. Finally, our study demonstrated that tea polyphenols play a protective role in ovarian mitochondrial dysfunction in low-concentration bisphenol A-exposed female zebrafish.

A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam - Yi-Fan Yu; Yue-Qian Li; Ru-Yue Wang; Xu Liu; Wen-Bo Cui; Xiao-Han Chen; Cheng-Mu Zhao; Feng-Ming Qi; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

BSA‑seq and genetic mapping reveals AhRt2 as a candidate gene responsible for red testa of peanut - Kun Zhang; Mei Yuan; Han Xia; Liangqiong He; Jing Ma; Mingxiao Wang; Huiling Zhao; Lei Hou; Shuzhen Zhao; Pengcheng Li; Ruizheng Tian; Jiaowen Pan; et al. (Theoretical and Applied Genetics, 2022)

Coastal buoy observation of air-sea net heat flux in the East China Sea in summer 2020 - Yuting Han; Yangang Li; Changsan Xu; Lei Liu; Yanling Zhao; Wenqing Li; Xiangzhou Song (Journal of Oceanology and Limnology, 2022)

Full-Length Transcriptome Data for the White Cloud Mountain Minnow (Tanichthys albonubes) From a Wild Population Based on Isoform Sequencing - Chao Li; Shenhang Zhong; Jinjin Jin; Han Xiao; Junjie Wang; Jun Zhao (Frontiers in Marine Science, 2022)

Target lines for recombinase-mediated gene stacking in soybean - Li Jiang; Ruyu Li; Zhiguo Han; Xiaohui Zhao; Dong Cao; David W. Ow (Theoretical and Applied Genetics, 2022)

Small signaling peptides mediate plant adaptions to abiotic environmental stress - Heping Xie; Wen Zhao; Weilin Li; Yuzhou Zhang; Jakub Hajný; Huibin Han (Planta, 2022)

Overexpression of Cpg15 Alleviates the Oxidative Stress in Neuronal Cells Via Regulating Redox Enzymes and Nrf2 Antioxidative Pathway - Yi Jiang; Jun-Jie Li; Ya-Wei Mu; Han-Yang Jiang; Zi-Xuan Wei; Zi-Yao Xiao; Jing-Jing Zhao; Xian-Hua Chen (Neurotoxicity Research, 2022)

Characteristic Strength and Energy Evolution Law of Coal Treated by Ultrasonic Wave with Different Power Under Uniaxial Compression - Erhao Yang; Haifei Lin; Shugang Li; Pengxiang Zhao; Lei Qin; Ruizhe Wang; Shuangze Han (Natural Resources Research, 2022)

Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma - Peipei Han; Shu Wu; Limei Li; Danping Li; Jun Zhao; Haishan Zhang; Yifang Wang; Xuemin Zhong; Zhe Zhang; Ping Li; Liudmila Matskova; Xiaoying Zhou (Genes & Genomics, 2022)

Correction to: Role of HMGB1 in TNF-α Combined with Z-VAD-fmk-Induced L929 Cells Necroptosis - Zhao Lei; Can Yu; Xia Li; Li-Hua Huang; Zhi-Qiang Li; Hong-Wei Zhu; Duo Han; Hui Huang; Xiao Yu (Biochemical Genetics, 2022)

Role of HMGB1 in TNF-α Combined with Z-VAD-fmk-Induced L929 Cells Necroptosis - Can Yu; Zhao Lei; Xia Li; Li-Hua Huang; Zhi-Qiang Li; Hong-Wei Zhu; Duo Han; Hui Huang; Xiao Yu (Biochemical Genetics, 2022)

Multiple fracture, dissolution, and cementation events of Ordovician carbonate reservoirs in T-SH Oilfield, Tarim Basin - Teng Zhao; Rui Zhao; Chongyang Xiao; Jun Han; Anpeng Kuang; Yingtao Li (Arabian Journal of Geosciences, 2022)

Baicalin attenuates amyloid β oligomers induced memory deficits and mitochondria fragmentation through regulation of PDE-PKA-Drp1 signalling - Hai-Yang Yu; Ye Zhu; Xin-Li Zhang; Lei Wang; Yan-Meng Zhou; Fang-Fang Zhang; Han-Ting Zhang; Xiao-Min Zhao (Psychopharmacology, 2022)

Climatic controls of Pinus pumila radial growth along an altitude gradient - Jingwen Yang; David J. Cooper; Xu Zhang; Wenqi Song; Zongshan Li; Yuandong Zhang; Huiying Zhao; Shijie Han; Xiaochun Wang (New Forests, 2022)

Correction to: Determination of interactions of ferrihydrite‑humic acid‑Pb (II) system - Zhuanjun Zhao; Liwei Yao; Jie Li; Xiangbang Ma; Liangwei Han; Zhiyuan Lin; Shuqi Guan (Environmental Science and Pollution Research, 2022)

Determination of interactions of ferrihydrite-humic acid-Pb (II) system - Zhuanjun Zhao; Liwei Yao; Jie Li; Xiangbang Ma; Liangwei Han; Zhiyuan Lin; Shuqi Guan (Environmental Science and Pollution Research, 2022)

Cr release after Cr(III) and Cr(VI) enrichment from different layers of cast iron corrosion scales in drinking water distribution systems: the impact of pH, temperature, sulfate, and chloride - Yimei Tian; Tiantian Yu; Jingyi Shen; Guolei Zheng; Han Li; Weigao Zhao (Environmental Science and Pollution Research, 2022)

Spatial–temporal evolution pattern and prediction analysis of flood disasters in China in recent 500 years - Cuixia Wei; Bing Guo; Hailing Zhang; Baomin Han; Xiangshen Li; Huihui Zhao; Yuefeng Lu; Chao Meng; Xiangzhi Huang; Wenqian Zang; Hongwei Wu (Earth Science Informatics, 2022)

Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components - Tingting Lin; Jiaqi Tao; Ying Chen; Yitong Zhang; Fenglan Li; Yutong Zhang; Xueqing Han; Zihui Zhao; Guiyan Liu; Hui Li (Biological Trace Element Research, 2022)

Exosomal miRNA-328-3p targets ZO-3 and inhibits porcine epidemic diarrhea virus proliferation - Han Zhao; Jinxin Yang; Qian Wang; Zhanding Cui; Dengliang Li; Jiangting Niu; Yanbing Guo; Qian Zhang; Shuang Zhang; Yanli Zhao; Kai Wang; Wei Lian; et al. (Archives of Virology, 2022)

Extracellular Vesicle Application as a Novel Therapeutic Strategy for Ischemic Stroke - Yiyang Li; Bowen Liu; Ying Chen; Xingping Quan; Yan Han; Ying Zheng; Yonghua Zhao (Translational Stroke Research, 2022)

Shifting from homogeneous to heterogeneous surfaces in estimating terrestrial evapotranspiration: Review and perspectives - Yuanbo Liu; Guoyu Qiu; Hongsheng Zhang; Yonghui Yang; Yinsheng Zhang; Quan Wang; Wenzhi Zhao; Li Jia; Xibin Ji; Yujiu Xiong; Chunhua Yan; Ning Ma; et al. (Science China Earth Sciences, 2022)

Ameliorating Effect of Umbilical Cord Mesenchymal Stem Cells in a Human Induced Pluripotent Stem Cell Model of Dravet Syndrome - Huifang Zhao; Shuai Li; Lang He; Feng Tang; Xiaobo Han; Weiyue Deng; Zuoxian Lin; Rongqi Huang; Zhiyuan Li (Molecular Neurobiology, 2022)

Video target detection of East Asian migratory locust based on the MOG2-YOLOv4 network - Zhao Bai; Zhan Tang; Lei Diao; Shuhan Lu; Xuchao Guo; Han Zhou; Chengqi Liu; Lin li (International Journal of Tropical Insect Science, 2022)

Identification and characterization of microRNAs involved in double-color formation in Paeonia suffruticosa ‘Shima Nishiki’ by high-throughput sequencing - Xinpeng Zhang; Jinshan Jia; Mingyuan Zhao; Cheng Li; Xu Han; Zongda Xu (Horticulture, Environment, and Biotechnology, 2022)

Individual exposure to ambient PM2.5 and hospital admissions for COPD in 110 hospitals: a case-crossover study in Guangzhou, China - Jie-Qi Jin; Dong Han; Qi Tian; Zhao-Yue Chen; Yun-Shao Ye; Qiao-Xuan Lin; Chun-Quan Ou; Li Li (Environmental Science and Pollution Research, 2022)
Few studies have evaluated the short-term association between hospital admissions and individual exposure to ambient particulate matter (PM 2.5 ). Particularly, no studies focused on hospital admissions for chronic obstructive pulmonary disease (COPD) at the individual level. We assessed the short-term effects of PM 2.5 on hospitalization admissions for COPD in Guangzhou, China, during 2014–2015, based on satellite-derived estimates of ambient PM 2.5 concentrations at a 1-km resolution near the residential address as individual-level exposure for each patient. Around 40,002 patients with COPD admitted to 110 hospitals were included in this study. A time-stratified case-crossover design with conditional logistic regression models was applied to assess the effects of PM 2.5 based on a 1-km grid data of aerosol optical depth provided by the National Aeronautics and Space Administration on hospital admissions for COPD. Further, we performed stratified analyses by individual demographic characteristics and season of hospital admission. Around 10 μg/m 3 increase in individual-level PM 2.5 was associated with an increase of 1.6% (95% confidence interval [CI]: 0.6%, 2.7%) in hospitalization for COPD at a lag of 0–5 days. The impact of PM 2.5 on hospitalization for COPD was greater significantly in males and patients admitted in summer. Our study strengthened the evidence for the adverse effect of PM 2.5 based on satellite-based individual-level exposure data.

GATA4 Is a Transcriptional Regulator of SOX2 in Japanese Flounder (Paralichthys olivaceus) - Xiumei Liu; Zan Li; Weijie Yan; Haitao Zhao; Yuxiang Liu; Miao Han; Xubo Wang; Yan He; Haiyang Yu; Quanqi Zhang (Journal of Ocean University of China, 2022)

Temporal-spatial oceanic variation in relation with the three typical Kuroshio paths south of Japan - Xiaobo Wu; Yanling Zhao; Guijun Han; Wei Li; Qi Shao; Lige Cao; Chaoliang Li (Acta Oceanologica Sinica, 2022)

Research on hoop capacity of composite foundation of discarded rubber tires - Feng-Chi Wang; Jun Li; Zhen-Huan Lin; Pei-Pei Tian; Han-Yu Zhao (European Journal of Environmental and Civil Engineering, 2022)

Petrogenesis of the Late Triassic Mengsong strongly peraluminous granites in the southeastern Tibetan Plateau: highly fractionated from crystal mush - Feng Cong; Fu-Yuan Wu; Wen-Chang Li; De-Feng He; Zai-Bo Sun; Xiao-Ming Huang; Zhi-Zhong Hu; Han Zhao (International Geology Review, 2022)

Carbon dots based ratiometric fluorescent sensing platform for food safety - Yong Han; Weixia Yang; Xueli Luo; Xie He; Haiping Zhao; Wenzhi Tang; Tianli Yue; Zhonghong Li (Critical Reviews in Food Science and Nutrition, 2022)

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Tracing historical changes, degradation, and original sources of airborne polycyclic aromatic hydrocarbons (PAHs) in Jilin Province, China, by Abies holophylla and Pinus tabuliformis needle leaves - Zhao Wang; Xiangzi Jin; Han Yeong Kaw; Zakia Fatima; Maurizio Quinto; John L. Zhou; Dongri Jin; Miao He; Donghao Li (Environmental Science and Pollution Research, 2022)

Environmental drivers of phytoplankton crops and taxonomic composition in northeastern Antarctic Peninsula adjacent sea area - Yubin Feng; Dong Li; Jun Zhao; Zhengbing Han; Jianming Pan; Gaojing Fan; Haisheng Zhang; Ji Hu; Haifeng Zhang; Jiaqi Wu; Qiuhong Zhu (Acta Oceanologica Sinica, 2022)

Geochemistry and Sr–Nd isotopes of the Late Mesozoic lamprophyres in the Chaohu area, eastern China : Petrogenesis and tectonic implications - Mo Chen; Longming Li; Tianxiang Kan; Hang Liu; Xilin Zhao; Jiahao Li; Xu Han (Island Arc, 2022)
Late Mesozoic lamprophyres are widespread in the Chaohu area of the Lower Yangtze region, eastern China. These mantle‐derived rocks are of great significance for understanding the characteristics of mantle source and tectonic environment of eastern China during the Late Mesozoic. The lamprophyres from the Chaohu area can be divided into two types. The type‐I lamprophyres have low SiO 2 (43.8–44.5 wt.%) and TiO 2 (1.06–1.14 wt.%), high MgO (13.5–17.5 wt.%) and high contents of compatible elements, and are enriched in LREE and LILE but depleted in HFSE. They have high initial 87 Sr/ 86 Sr (0.70767–0.70904) and negative εNd ( t ) (−4.8 to −4.4). The type‐II lamprophyres are characterized by low contents of SiO 2 (43.0–45.4 wt.%), high TiO 2 (1.74–2.55 wt.%), MgO (9.17–15.4 wt.%), and compatible elements. They are also enriched in LREE and LILE but depleted in HFSE. They show enriched Sr‐Nd isotopic compositions with initial 87 Sr/ 86 Sr values (0.70773–0.70886) and εNd ( t ) values (−8.6 to −7.8). The type‐I lamprophyres show higher Mg # and MgO contents but significant lower TiO 2 than the type‐II lamprophyres. In addition, the type‐I lamprophyres have relatively similar initial 87 Sr/ 86 Sr ratios but higher εNd( t ) values than the type‐II lamprophyres. The difference of geochemical characteristics between the type‐I and type‐II lamprophyres may be caused by different degrees of partial melting of an amphibole‐bearing garnet lherzolite mantle. The lithospheric mantle was metasomatised by the fluids caused by the rollback of the Paleo‐Pacific plate subduction during the Late Cretaceous.

An accurate and robust registration framework based on outlier removal and feature point adjustment for remote sensing images - Han Yang; Xiaorun Li; Liaoying Zhao; Shuhan Chen (International Journal of Remote Sensing, 2021)

Quantitative proteomic and lipidomics analyses of high oil content GmDGAT1-2 transgenic soybean illustrate the regulatory mechanism of lipoxygenase and oleosin - Yang Xu; Fan Yan; Yajing Liu; Ying Wang; Han Gao; Shihui Zhao; Youcheng Zhu; Qingyu Wang; Jingwen Li (Plant Cell Reports, 2021)

Osteoarthritic infrapatellar fat pad aggravates cartilage degradation via activation of p38MAPK and ERK1/2 pathways - Zuoqing Zhou; Su’an Tang; Xiaoyu Nie; Yiqun Zhang; Delong Li; Yang Zhao; Yumei Cao; Jianwen Yin; Tianyu Chen; Guangfeng Ruan; Zhaohua Zhu; Xiaochun Bai; et al. (Inflammation Research, 2021)

Pollution characteristics, spatial distribution, and source identification of heavy metals in road dust in a central eastern city in China: a comprehensive survey - Guoyong Zhao; Ronglei Zhang; Yan Han; Jianing Meng; Qiang Qiao; Hetan Li (Environmental Monitoring and Assessment, 2021)

Exposure to 2,4-dichlorophenol, 2,4,6-trichlorophenol, pentachlorophenol and risk of thyroid cancer: a case-control study in China - Wan-Jun Yang; Hua-Bing Wu; Chi Zhang; Qi Zhong; Ming-Jun Hu; Jia-Liu He; Guo-Ao Li; Zhen-Yu Zhu; Jin-Liang Zhu; Huan-Huan Zhao; Han-Shuang Zhang; Fen Huang (Environmental Science and Pollution Research, 2021)

Spatiotemporal analysis and potential impact factors of vegetation variation in the karst region of Southwest China - Wei Chen; Shuang Bai; Haimeng Zhao; Xuerong Han; Lihe Li (Environmental Science and Pollution Research, 2021)

Echinicola salinicaeni sp. nov., a novel bacterium isolated from saltern mud - Han Zhao; Chun-Yi Song; Rui Yin; Yan-Jun Yi; Shuai-Ting Yun; Ying-Xiu Li; Yan-Xia Zhou (Antonie van Leeuwenhoek, 2021)

Community structure and abundance of comammox Nitrospira in Chongming eastern intertidal sediments - Dongyao Sun; Min Liu; Lijun Hou; Mengyue Zhao; Xiufeng Tang; Qiang Zhao; Jun Li; Ping Han (Journal of Soils and Sediments, 2021)

Regional brain network and behavioral alterations in EGR3 gene transfected rat model of schizophrenia - Wenwen Gao; Guangfei Li; Xiaowei Han; Zeyu Song; Shuai Zhao; Feiyi Sun; Hong Ma; Ailing Cui; Yige Wang; Xiuxiu Liu; Yue Chen; Lu Zhang; et al. (Brain Imaging and Behavior, 2021)

Association of myostatin deficiency with collagen related disease-umbilical hernia and tippy toe standing in pigs - Hyo-Jin Paek; Zhao-Bo Luo; Hak-Myong Choe; Biao-Hu Quan; Kai Gao; Sheng-Zhong Han; Zhou-Yan Li; Jin-Dan Kang; Xi-Jun Yin (Transgenic Research, 2021)

Imaging and clinical features of cervical artery web: report of 41 cases and literature review - Minghui Wang; Ruizhi Zhou; Han Zhao; Lei Niu; Song Liu; Ying Li; Xuejun Liu (Acta Neurologica Belgica, 2021)

Sesquiterpenoids from Artemisia argyi and their NO production inhibitory activity in RAW264.7 cells - Gui-Min Xue; Jin-Feng Xue; Chen-Guang Zhao; Zhen-Zhu Zhao; Yan-Jun Sun; Kun Du; Han-Wei Li; Wei-Sheng Feng (Natural Product Research, 2021)

Correlation of CD38 expression with the progression of hemorrhagic fever with renal syndrome - Han-Dong Zhao; Yan-Ping Li; Wei-Wei Zhao; Peng Li; Hong-Li Liu (Archives of Virology, 2021)

Interaction between the cell walls of microalgal host and fungal carbohydrate‐activate enzymes is essential for the pathogenic parasitism process - Juan Lin; Hailong Yan; Liang Zhao; Yanhua Li; Bahareh Nahidian; Mianmian Zhu; Qiang Hu; Danxiang Han (Environmental Microbiology, 2021)
Summary Fungi can parasitize microalgae, exerting profound impacts on both the aquatic ecosystems and microalgal mass cultures. In this study, the unicellular green alga Haematococcus pluvialis and the blastocladialean fungus Paraphysoderma sedebokerense were used as a model system to address the mechanisms underlying the fungal parasitism on the algal host. High‐throughput metabolic assay indicated that P . sedebokerense can utilize several carbon sources with a preference for mannose, glucose and their oligosaccharides, which was compatible with the profile of the host algal cell walls enriched with glucan and mannan. The results of dual transcriptomics analysis suggested that P . sedebokerense can upregulate a large number of putative carbohydrate‐activate enzymes (CAZymes) encoding genes, including those coding for the endo‐1,4‐β‐glucanase and endo‐1,4‐β‐mannanase during the infection process. The cell walls of H . pluvialis can be decomposed by both P . sedebokerense and commercial CAZymes (e.g. cellulase and endo‐1,4‐β‐mannanase) to produce mannooligomers, while several putative parasitism‐related genes of P . sedebokerense can be in turn upregulated by mannooligomers. In addition, the parasitism can be blocked by interfering the selected CAZymes including glucanase, mannanase and lysozyme with the specific inhibitors, which provided a framework for screening suitable compounds for pathogen mitigation in algal mass culture.

Identification of glutathione transferase gene associated with partial resistance to Sclerotinia stem rot of soybean using genome-wide association and linkage mapping - Zou Jianan; Wenjing Li; Yuting Zhang; Wei Song; Haipeng Jiang; Jingyun Zhao; Yuhang Zhan; Weili Teng; Lijuan Qiu; Xue Zhao; Yingpeng Han (Theoretical and Applied Genetics, 2021)

The downregulation of PpPG21 and PpPG22 influences peach fruit texture and softening - Ming Qian; Ze Xu; Zehua Zhang; Qin Li; Xiangyan Yan; Hangkong Liu; Mingyu Han; Furui Li; Jicheng Zheng; Dong Zhang; Caiping Zhao (Planta, 2021)

Short-term effects of soil moisture on soil organic carbon decomposition in a coastal wetland of the Yellow River Delta - Wendi Qu; Guangxuan Han; Jian Wang; Juanyong Li; Mingliang Zhao; Wenjun He; Xinge Li; Siyu Wei (Hydrobiologia, 2021)

Genomic selection to introgress exotic maize germplasm into elite maize in China to improve kernel dehydration rate - Hongjun Yong; Nan Wang; Xiaojun Yang; Fengyi Zhang; Juan Tang; Zhiyuan Yang; Xinzhe Zhao; Yi Li; Mingshun Li; Degui Zhang; Zhuanfang Hao; Jianfeng Weng; et al. (Euphytica, 2021)

Mapping of a major QTL for salinity tolerance at the bud burst stage in rice (Oryza sativa L) using a high-density genetic map - Lei Lei; Zhenghong Han; Bowen Cui; Luomiao Yang; Hualong Liu; Jingguo Wang; Hongwei Zhao; Wei Xin; Xianwei Li; Jiaming Li; Jingnan Cui; Shanbin Xu; et al. (Euphytica, 2021)

Frequency-specific altered global signal topography in drug-naïve first-episode patients with adolescent-onset schizophrenia - Xiao Wang; Wei Liao; Shaoqiang Han; Jiao Li; Yifeng Wang; Yan Zhang; Jingping Zhao; Huafu Chen (Brain Imaging and Behavior, 2021)

Whole brain volume and cortical thickness abnormalities in Wilson’s disease: a clinical correlation study - Yukun Song; Lin Zou; Jing Zhao; Xiangxue Zhou; Yingqian Huang; Haishan Qiu; Haiwei Han; Zhiyun Yang; Xunhua Li; Xiaoying Tang; Jianping Chu (Brain Imaging and Behavior, 2021)

Genome-wide association analysis for yield-related traits at the R6 stage in a Chinese soybean mini core collection - Xiangnan Li; Yang Zhou; Yuanpeng Bu; Xinfang Wang; Yumei Zhang; Na Guo; Jinming Zhao; Han Xing (Genes & Genomics, 2021)

Microbacterium helvum sp. nov., a novel actinobacterium isolated from cow dung - Xiao Li; Lida Zhang; Fuyan Huang; Junwei Zhao; Han Wang; Yanjie Jiao; Lulu Qian; Xiangjing Wang; Wensheng Xiang (Archives of Microbiology, 2021)

Deep Learning Model for the Automated Detection and Histopathological Prediction of Meningioma - Hua Zhang; Jiajie Mo; Han Jiang; Zhuyun Li; Wenhan Hu; Chao Zhang; Yao Wang; Xiu Wang; Chang Liu; Baotian Zhao; Jianguo Zhang; Kai Zhang (Neuroinformatics, 2021)

Characteristics of RNA alternative splicing and its potential roles in ginsenoside biosynthesis in a single plant of ginseng, Panax ginseng C.A. Meyer - Yilai Han; Lei Zhu; Li Li; Yanfang Wang; Mingzhu Zhao; Kangyu Wang; Chunyu Sun; Jing Chen; Lingyu Liu; Ping Chen; Jun Lei; Yi Wang; et al. (Molecular Genetics and Genomics, 2021)

Interactive effect of water level and flushing rate on population dynamics of a harmful cyanobacterial species: Raphidiopsis raciborskii - Quehui Tang; Lamei Lei; Li Zhao; Jiguang Gu; Lijuan Xiao; Bo-Ping Han (Ecotoxicology, 2021)

Genome-wide Identification and Expression Pattern Analysis of the HD-Zip Transcription Factor Family in Pineapple (Ananas Comosus) - Qiao Zhou; Liping Liu; Han Cheng; Zeyun Li; MyatHnin Wai; Tiantian Luo; Xingyue Jin; Heming Zhao; S. V. G. N. Priyadarshani; Yuan Qin (Tropical Plant Biology, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Regulation of mGluR1 on the Expression of PKC and NMDAR in Aluminum-Exposed PC12 Cells - Chanting He; Xiaoyan Zhao; Huan Li; Fei Wang; Jingsi Zhang; Yanni Wang; Yingchao Han; Chunman Yuan; Qiao Niu (Neurotoxicity Research, 2021)

Electrophysiological correlates of visual attention span in Chinese adults with poor reading fluency - Jiaxiao Li; Jing Zhao; Junxia Han; Hanlong Liu (Experimental Brain Research, 2021)

Exploring the long-term vegetation dynamics of different ecological zones in the farming-pastoral ecotone in northern China - Wei Chen; Aijia Li; Yungang Hu; Lihe Li; Haimeng Zhao; Xuerong Han; Bin Yang (Environmental Science and Pollution Research, 2021)

The Effects of Metal Exposures on Charlson Comorbidity Index Using Zero-Inflated Negative Binomial Regression Model: NHANES 2011–2016 - Hantong Zhao; Yingan Pan; Changcong Wang; Yinpei Guo; Nan Yao; Han Wang; Bo Li (Biological Trace Element Research, 2021)

Effect of urban underlying surface on PM2.5 vertical distribution based on UAV in Xi’an, China - Kai Xin; Jingyuan Zhao; Xuan Ma; Li Han; Yanyu Liu; Jianxin Zhang; Yuejing Gao (Environmental Monitoring and Assessment, 2021)

Herbidospora solisilvae sp. nov., a novel cellulose-degrading actinobacterium isolated from forest soil - Mingying Yu; Rui Zhou; Jingjing Li; Liyuan Han; Han Wang; Siyu Zhang; Junwei Zhao; Xiangjing Wang; Jia Song; Wensheng Xiang (Antonie van Leeuwenhoek, 2021)

A study of hydrophobins-modified menaquinone-7 on osteoblastic cells differentiation - Hengfang Tang; Zhu Zhu; Zhiming Zheng; Han Wang; Chu Li; Li Wang; Genhai Zhao; Peng Wang (Molecular and Cellular Biochemistry, 2021)

Comparative analysis of genetic diversity of rice (Oryza sativa L.) varieties cultivated in different periods in China - Ruyu Tang; Di Cui; Jian Zhou; Wenqiu Li; Xiaoding Ma; Bing Han; Xiaohong Guo; Zhengwu Zhao; Longzhi Han (Genetic Resources and Crop Evolution, 2021)

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Review of Huang-huai sheep, a new multiparous mutton sheep breed first identified in China - Kai Quan; Jun Li; Haoyuan Han; Hongfang Wei; Jinyan Zhao; HA Si; Xinji Zhang; Daojiang Zhang (Tropical Animal Health and Production, 2021)
Huang-huai sheep are a new multiparous mutton sheep breed that has been cultivated by domestic scientific research institutes, governments, and sheep farms in China. Huang-huai sheep were bred using Dorper sheep as a sire and Small-tailed Han sheep as a dam. The breeding of Huang-huai sheep started in 2003, and three stages have been carried out: crossbreeding innovation, fixation in a two-way-crossbred closed flock, and herd propagation. A pilot test of Huang-huai sheep was conducted on 6 sheep farms from 2017 to 2018, and hereditary properties and production performance were evaluated in 2019. Huang-huai sheep were identified on site by the National Livestock and Poultry Resources Committee of China in December 2019 and approved as a new multiparous mutton sheep breed in China. The genetic distance showed that Huang-huai sheep are most closely related to Dorper sheep, Luxi black-headed sheep, and Small-tailed Han sheep, but the genetic distances are subspecies (0.02–0.20) each other. The body weights of adult Huang-huai sheep are 98.1 ± 5.2 kg (♂) and 71.7 ± 3.5 kg (♀), and those of 6-month-old Huang-huai sheep are 58.50 ± 6.55 kg (♂) and 52.45 ± 5.67 kg (♀). The slaughter rates of 6-month-old sheep are 56.02 ± 1.25% (♂) and 53.19 ± 1.19% (♀). The estrus cycle of Huang-huai sheep is 19.32 ± 2.8 days, the first estrus cycle occurs at 168 ± 12 days, the annual lambing rate of ewes is 252.82% ± 10.69%, the survival rate of lambs is 95.79 ± 0.95%, and the number of weaned lambs per ewe per year is 2.38 ± 0.14. The growth performance, carcass quality, and reproductive performance of Huang-huai sheep have been improved, resulting in considerable economic and social benefits and broader market prospects. This breed represents a new multiparous mutton sheep breed adapted for industrial sheep farms in China.

Seismic wave equations in tight oil/gas sandstone media - Jinghuai Gao; Weimin Han; Yanbin He; Haixia Zhao; Hui Li; Yijie Zhang; Zongben Xu (Science China Earth Sciences, 2021)

Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling - Li Zhang; Lu Wang; Han Xiao; Hui Gan; Hui Chen; Shuyue Zheng; Dan Jian; Xuan Zhai; Ning Jiang; Zhao Jing; Ping Liang (Journal of Molecular Medicine, 2021)

Gga-miR-181a modulates ANP32A expression and inhibits MDCC-MSB-1 cell - X. Li; C. Zhao; B. Han; L. Qu; C. Liu; N. Yang; L. Lian (In Vitro Cellular & Developmental Biology - Animal, 2021)

Analysis of slug interference tests conducted in an artificial fracture - Yunfeng Dai; Yanrong Zhao; Jin Lin; Jiangbo Han; Xiaomin Sun; Wei Li; Jiufu Liu (Hydrogeology Journal, 2021)

Enhanced antioxidant capacity and upregulated transporter genes contribute to the UV-B-induced increase in blinin in Conyza blinii - Junyi Zhan; Qin Yang; Zhiyi Lin; Tianrun Zheng; Maojia Wang; Wenjun Sun; Tongliang Bu; Zizhong Tang; Chenglei Li; Xueyi Han; Haixia Zhao; Qi Wu; et al. (Environmental Science and Pollution Research, 2021)

Serum Ceruloplasmin Is the Candidate Predictive Biomarker for Acute Aortic Dissection and Is Related to Thrombosed False Lumen: a Propensity Score–Matched Observational Case–Control Study - Changcheng Ma; Haibin Zhao; Feng Shi; Mu Li; Xun Liu; Chao Ji; Yanshuo Han (Biological Trace Element Research, 2021)

Study on the Triaxial Unloading Creep Mechanical Properties and Damage Constitutive Model of Red Sandstone Containing a Single Ice-Filled Flaw - Ren-liang Shan; Yao Bai; Yang Ju; Tian-yu Han; Hao-yu Dou; Zhao-long Li (Rock Mechanics and Rock Engineering, 2021)

A candidate PpRPH gene of the D locus controlling fruit acidity in peach - Lu Wang; Xiaohan Jiang; Li Zhao; Furong Wang; Yudi Liu; Hui Zhou; Huaping He; Yuepeng Han (Plant Molecular Biology, 2021)

TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial–mesenchymal transition - Zhi-Han Li; Lei Lei; Liang-Ru Fei; Wen-Jing Huang; Yi-Wen Zheng; Mai-Qing Yang; Zhao Wang; Chen-Chen Liu; Hong-Tao Xu (Journal of Molecular Histology, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Partial recovery of disturbed V-J pairing profiles of T-cell receptor in people living with HIV receiving long-term antiretroviral therapy - Guoli Li; Jiarui Li; Henghui Zhang; Yu Zhang; Di Liu; Yu Hao; Junyan Han; Juan Du; Liuluan Zhu; Yongqin Zeng; Bei Li; Rui Li; et al. (Science China Life Sciences, 2021)

Functions of RPM1-interacting protein 4 in plant immunity - Guangdong Zhao; Dezheng Guo; Lijun Wang; Han Li; Chen Wang; Xingqi Guo (Planta, 2021)

Comparative genomic analysis of superoxide dismutase (SOD) genes in three Rosaceae species and expression analysis in Pyrus bretschneideri - Guohui Li; Fei Hu; Yang Zhang; Yu Zhao; Han Wang; Tianzhe Chen; Xi Cheng; Yongping Cai (Physiology and Molecular Biology of Plants, 2021)

MiRNA-seq analysis of spleen and head kidney tissue from aquacultured largemouth bass (Micropterus salmoides) in response to Aeromonas hydrophila infection - Jian Zhou; Han Zhao; Lu Zhang; Qiang Li; Zhipeng Huang; Zhongmeng Zhao; Hongyu Ke; Yu Xiao; Xutao Su; Qiao Liu; Song Yang; Liulan Zhao (Functional & Integrative Genomics, 2021)

Exploring difference in land surface temperature between the city centres and urban expansion areas of China’s major cities - Jiyao Zhao; Le Yu; Yidi Xu; Xuecao Li; Yuyu Zhou; Dailiang Peng; Han Liu; Xiaomeng Huang; Zheng Zhou; Dong Wang; Chao Ren; Peng Gong (International Journal of Remote Sensing, 2020)

Dynamic Variations in Brain Glycogen are Involved in Modulating Isoflurane Anesthesia in Mice - Ze Fan; Zhihao Zhang; Shiyi Zhao; Yuanyuan Zhu; Dong Guo; Bo Yang; Lixia Zhuo; Jiao Han; Rui Wang; Zongping Fang; Hailong Dong; Yan Li; et al. (Neuroscience Bulletin, 2020)
General anesthesia severely affects the metabolites in the brain. Glycogen, principally stored in astrocytes and providing the short-term delivery of substrates to neurons, has been implicated as an affected molecule. However, whether glycogen plays a pivotal role in modulating anesthesia–arousal remains unclear. Here, we demonstrated that isoflurane-anesthetized mice exhibited dynamic changes in the glycogen levels in various brain regions. Glycogen synthase (GS) and glycogen phosphorylase (GP), key enzymes of glycogen metabolism, showed increased activity after isoflurane exposure. Upon blocking glycogenolysis with 1,4-dideoxy-1,4-imino-D-arabinitol (DAB), a GP antagonist, we found a prolonged time of emergence from anesthesia and an enhanced δ frequency in the EEG (electroencephalogram). In addition, augmented expression of glycogenolysis genes in glycogen phosphorylase, brain (Pygb) knock-in (Pygb H11/H11 ) mice resulted in delayed induction of anesthesia, a shortened emergence time, and a lower ratio of EEG-δ. Our findings revealed a role of brain glycogen in regulating anesthesia–arousal, providing a potential target for modulating anesthesia.

Update on recommendations for the diagnosis and treatment of SARS-CoV-2 infection in children - Hongjun Miao; Han Li; Yinying Yao; Mingfu Wu; Chao Lu; Jun Wang; Man Tian; Ying Li; Peiliang Luo; Jianhui Gu; Bin Yuan; Shouchuan Wang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2020)
Since the outbreak of novel coronavirus infection pneumonia in Wuhan City, China, in late 2019, such cases have been gradually reported in other parts of China and abroad. Children have become susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) because of their immature immune function. As the outbreak has progressed, more cases of novel coronavirus infection/pneumonia in children have been reported. Compared with adults, the impact of SARS-CoV-2 infection in children is less severe, with a lower incidence and susceptibility in children, which results in fewer children being tested, thereby underestimating the actual number of infections. Therefore, strengthening the diagnosis of the disease is particularly important for children, and early and clear diagnosis can determine treatment strategies and reduce the harm caused by the disease to children. According to the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards ( trial version 7 ) issued by National Health Committee and the latest diagnosis and treatment strategies for novel coronavirus infection pneumonia in children, this review summarizes current strategies on diagnosis and treatment of SARS-CoV-2 infection in children.

Application of comprehensive support techniques to roadway tunneling in vicinity of Ordovician carbonate confined aquifers under complicated tectonic conditions - Huiyong Yin; Cuiyue Zhao; Yutao Zhai; Shizhen Sang; Han Zhao; Shujing Li; Haisong Li; Weijie Zhang; Xuehou Zhuang (Carbonates and Evaporites, 2020)

The change of fracture conductivity caused by coal fines with different particle sizes displaced by single-phase water - Xiaoming Ni; Quanzhong Li; Zheng Zhao; Zedong Liu; Wenlong Han (Arabian Journal of Geosciences, 2020)

Prevalence, Molecular Characterization and Risk Factors of Blastocystis sp. from Farmed Pigs in Yunnan Province, Southwestern China - Jian Qiang Han; Zhao Li; Yang Zou; Li Hua Pu; Xin Quan Zhu; Feng Cai Zou; Cui-Qin Huang (Acta Parasitologica, 2020)

In vitro dual-target activities and in vivo antidiabetic effect of 3-hydroxy-N-(p-hydroxy-phenethyl) phthalimide in high-fat diet and streptozotocin-induced diabetic golden hamsters - Bin Xiao; Yunfeng Xiao; Haining Ning; Xiaoyan Han; Wenyan Li; Yuheng Ma; Na Zhao; Guanhua Du; Yu Dong; Jee H. Jung; Zhanfei She (Medicinal Chemistry Research, 2020)

The combinatory effects of natural products and chemotherapy drugs and their mechanisms in breast cancer treatment - Yubo Zhang; Huajun Li; Jing Zhang; Chaoran Zhao; Shuai Lu; Jinping Qiao; Mei Han (Phytochemistry Reviews, 2020)

Transient receptor potential ankyrin 1 contributes to the ATP-elicited oxidative stress and inflammation in THP-1-derived macrophage - Chao Tian; Xiaobo Han; Lang He; Feng Tang; Rongqi Huang; Zuoxian Lin; Shuai Li; Sihao Deng; Junjie Xu; Hualin Huang; Huifang Zhao; Zhiyuan Li (Molecular and Cellular Biochemistry, 2020)

Cloning and Characterization of a Ginsenoside-Hydrolyzing α-L-Arabinofuranosidase, CaAraf51, From Cellulosimicrobium aquatile Lyp51 - Sha-Sha Zuo; Yu-Chen Wang; Ling Zhu; Jiang-Yuan Zhao; Ming-Gang Li; Xiu-Lin Han; Meng-Liang Wen (Current Microbiology, 2020)

Soil fungal taxonomic diversity along an elevation gradient on the semi-arid Xinglong Mountain, Northwest China - Salman Khan; Ning Chen; Cankun Zhang; Luning Wang; Chun Han; Kanglong Lu; Yage Li; Muhammad Rafiq; Awais Iqbal; Changming Zhao (Archives of Microbiology, 2020)

Brain interstitial fluid drainage and extracellular space affected by inhalational isoflurane: in comparison with intravenous sedative dexmedetomidine and pentobarbital sodium - Guomei Zhao; Hongbin Han; Jun Yang; Min Sun; Dehua Cui; Yuanyuan Li; Yajuan Gao; Jing Zou (Science China Life Sciences, 2020)

Inundation depth affects ecosystem CO2 and CH4 exchange by changing plant productivity in a freshwater wetland in the Yellow River Estuary - Mingliang Zhao; Guangxuan Han; Haitao Wu; Weimin Song; Xiaojing Chu; Juanyong Li; Wendi Qu; Xinge Li; Siyu Wei; Franziska Eller; Changsheng Jiang (Plant and Soil, 2020)

NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy - Han Xiao; Hui Chen; Rong Jiang; Li Zhang; Lu Wang; Hui Gan; Ning Jiang; Jing Zhao; Xuan Zhai; Ping Liang (Journal of Molecular Medicine, 2020)

Anti-inflammatory canthin-6-one alkaloids from the roots of Thailand Eurycoma longifolia Jack - Ying Zhang; Wei Zhao; Jingya Ruan; Nuttapong Wichai; Zheng Li; Lifeng Han; Yi Zhang; Tao Wang (Journal of Natural Medicines, 2020)

CDOM in the source regions of the Yangtze and Yellow Rivers, China: optical properties, possible sources, and their relationships with environmental variables - Dianbao Li; Baozhu Pan; Xing Zheng; Xiaoming Jiang; Gengnan Zhao; Xu Han (Environmental Science and Pollution Research, 2020)

ISLR regulates skeletal muscle atrophy via IGF1-PI3K/Akt-Foxo signaling pathway - Can Cui; Shunshun Han; Xiaoxu Shen; Haorong He; Yuqi Chen; Jing Zhao; Yuanhang Wei; Yan Wang; Qing Zhu; Diyan Li; Huadong Yin (Cell and Tissue Research, 2020)

Drug Elimination Alteration in Acute Lymphoblastic Leukemia Mediated by Renal Transporters and Glomerular Filtration - Yue Zhou; Bin Du; Min Kan; Shang Chen; Bo-Hao Tang; Ai-Qing Nie; Pan-Pan Ye; Hai-Yan Shi; Guo-Xiang Hao; Xiu-Li Guo; Qiu-Ju Han; Yi Zheng; et al. (Pharmaceutical Research, 2020)

The characteristics and genome analysis of vB_ApiP_XC38, a novel phage infecting Acinetobacter pittii - Mengjun Cheng; Man Luo; Hengyu Xi; Yunze Zhao; Shuai Le; Li-Kuang Chen; Demeng Tan; Yuan Guan; Tianqi Wang; Wenyu Han; Nannan Wu; Tongyu Zhu; et al. (Virus Genes, 2020)

Pseudorabies virus encephalitis in humans: a case series study - Siyuan Fan; Hongxun Yuan; Lei Liu; Hongfang Li; Shengnan Wang; Weili Zhao; Yihan Wu; Pei Wang; Yafang Hu; Jun Han; Yanli Lyu; Wuchao Zhang; et al. (Journal of NeuroVirology, 2020)

Effects of Atmospheric Precipitation on Heavy Metal Accumulation and Deactivation Amendment in Wheat Around a Lead Smelter - Le Song; Zhantao Han; Zhanjiang Li; Guizhang Zhao; Ruirang Yang (Water, Air, & Soil Pollution, 2020)

Plant height and its relationship with yield in wheat under different irrigation regime - Zhenxian Gao; Yanxia Wang; Guoying Tian; Yankun Zhao; Caihua Li; Qiao Cao; Ran Han; Zhanliang Shi; Mingqi He (Irrigation Science, 2020)

Full genome sequence of a new mitovirus from the phytopathogenic fungus Rhizoctonia solani - Siwei Li; Yuting Li; Chenghui Hu; Chenggui Han; Tao Zhou; Can Zhao; Xuehong Wu (Archives of Virology, 2020)

Miscanthus cultivation shapes rhizosphere microbial community structure and function as assessed by Illumina MiSeq sequencing combined with PICRUSt and FUNGUIld analyses - Yan Chen; Wei Tian; Yang Shao; Ying-Jun Li; Li-An Lin; Ying-Jun Zhang; Hui Han; Zhao-Jin Chen (Archives of Microbiology, 2020)

Roles of insulin-like growth factor II in regulating female reproductive physiology - Tahir Muhammad; Mengjing Li; Jianfeng Wang; Tao Huang; Shigang Zhao; Han Zhao; Hongbin Liu; Zi-Jiang Chen (Science China Life Sciences, 2020)

Shortened snRNA promoters for efficient CRISPR/Cas-based multiplex genome editing in monocot plants - Yu Hao; Wubei Zong; Dongchang Zeng; Jingluan Han; Shuifu Chen; Jianian Tang; Zhe Zhao; Xiaojuan Li; Kun Ma; Xianrong Xie; Qinlong Zhu; Yuanling Chen; et al. (Science China Life Sciences, 2020)

Synthesis, pharmacological evaluation and molecular docking of novel R-/S-2-(2-hydroxypropanamido)-5-trifluoromethyl benzoic acid as dual anti-inflammatory anti-platelet aggregation agents - Rong Rong; Rui-zhen Zhang; Xin Wang; Yu-han Dan; Yun-li Zhao; Zhi-guo Yu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

GelMA combined with sustained release of HUVECs derived exosomes for promoting cutaneous wound healing and facilitating skin regeneration - Danyang Zhao; Zhencheng Yu; Yun Li; Yu Wang; Qingfeng Li; Dong Han (Journal of Molecular Histology, 2020)

Coupled data assimilation and parameter estimation in coupled ocean–atmosphere models: a review - Shaoqing Zhang; Zhengyu Liu; Xuefeng Zhang; Xinrong Wu; Guijun Han; Yuxin Zhao; Xiaolin Yu; Chang Liu; Yun Liu; Shu Wu; Feiyu Lu; Mingkui Li; et al. (Climate Dynamics, 2020)

Comparison of sedimentary organic carbon loading in the Yap Trench and other marine environments - Dong Li; Jun Zhao; Chenggang Liu; Chengjun Sun; Jianfang Chen; Jianming Pan; Zhengbing Han; Ji Hu (Journal of Oceanology and Limnology, 2020)

Study on Pollution Characterization and Source Apportionment of Daytime and Nighttime PM2.5 Samples in an Urban Residential Community in Different Weather Conditions - Yan Zhao; Lihong Feng; Yuwen Wang; Bodong Shang; Jianping Li; Penghao Han (Bulletin of Environmental Contamination and Toxicology, 2020)

Illumina MiSeq sequencing and network analysis the distribution and co-occurrence of bacterioplankton in Danjiangkou Reservoir, China - Zhao-Jin Chen; Ge Xu; Chuan-Yu Ding; Bao-Hai Zheng; Yan Chen; Hui Han; Yu-Ying Li; Jian-Wei Shi; Lan-Qun Hu (Archives of Microbiology, 2020)

Resolving rupture processes of great earthquakes: Reviews and perspective from fast response to joint inversion - Han Yue; Yong Zhang; Zengxi Ge; Teng Wang; Li Zhao (Science China Earth Sciences, 2020)

Decrypting the crosstalk of noncoding RNAs in the progression of IPF - Yujuan Wang; Han Xiao; Fenglian Zhao; Han Li; Rong Gao; Bingdi Yan; Jin Ren; Junling Yang (Molecular Biology Reports, 2020)
Idiopathic pulmonary fibrosis (IPF) is an agnogenic, rare, and lethal disease, with high mortality and poor prognosis and a median survival time as short as 3 to 5 years after diagnosis. No effective therapeutic drugs are still not available not only in clinical practice, but also in preclinical phases. To better and deeper understand pulmonary fibrosis will provide more effective strategies for therapy. Mounting evidence suggests that noncoding RNAs (ncRNAs) and their interactions may contribute to lung fibrosis; however, the mechanisms underlying their roles are largely unknown. In this review, we systematically summarized the recent advances regarding the crucial roles of long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and circular RNAs (circRNAs) and crosstalk among them in the development of IPF. The perspective for related genes was well highlighted. In summary, ncRNA and their interactions play a key regulatory part in the progression of IPF and are bound to provide us with new diagnostic and therapeutic targets.

Effect of five modified mass selection cycles on combining ability in two Chinese maize populations - Hongjun Yong; Juan Tang; Xinzhe Zhao; Fengyi Zhang; Zhiyuan Yang; Yi Li; Mingshun Li; Degui Zhang; Zhuanfang Hao; Jianfeng Weng; Jienan Han; Bo Peng; et al. (Euphytica, 2020)

Genetic removal of the CH1 exon leads to the production of hypofunctional heavy chain-only IgG2a in rats - Zhenrong Li; Ming Zhang; Shunan Zheng; Yu Song; Xueqian Cheng; Di Yu; Lijuan Du; Liming Ren; Haitang Han; Yaofeng Zhao (Transgenic Research, 2020)

Design and Synthesis of Polymer Prodrugs for Improving Water-Solubility, Pharmacokinetic Behavior and Antitumor Efficacy of TXA9 - Yiwen Li; Chun Ye; Chengcheng Cai; Meng Zhao; Na Han; Zhihui Liu; Jianxiu Zhai; Jun Yin (Pharmaceutical Research, 2020)

Membrane proteomic analysis reveals the intestinal development is deteriorated by intrauterine growth restriction in piglets - Shimeng Huang; Cong Liu; Na Li; Zhenhua Wu; Tiantian Li; Dandan Han; Zhen Li; Jiangchao Zhao; Junjun Wang (Functional & Integrative Genomics, 2020)

Transient Receptor Potential Ankyrin 1 Contributes to Lysophosphatidylcholine-Induced Intracellular Calcium Regulation and THP-1-Derived Macrophage Activation - Chao Tian; Rongqi Huang; Feng Tang; Zuoxian Lin; Na Cheng; Xiaobo Han; Shuai Li; Peng Zhou; Sihao Deng; Hualin Huang; Huifang Zhao; Junjie Xu; et al. (The Journal of Membrane Biology, 2020)

Ketamine Alleviates Fear Generalization Through GluN2B-BDNF Signaling in Mice - Muhammad Asim; Bo Hao; Yu-Han Yang; Bu-Fang Fan; Li Xue; Yan-Wei Shi; Xiao-Guang Wang; Hu Zhao (Neuroscience Bulletin, 2020)

NOD1 inhibits proliferation and enhances response to chemotherapy via suppressing SRC-MAPK pathway in hepatocellular carcinoma - Xiaomin Ma; Yumin Qiu; Lihui Zhu; Yunxue Zhao; Yueke Lin; Dapeng Ma; Zhenzhi Qin; Caiyu Sun; Xuecheng Shen; Tao Li; Lihui Han (Journal of Molecular Medicine, 2020)

Modulation of boreal extended summer tropical cyclogenesis over the northwest Pacific by the quasi‐biweekly oscillation under different El Niño‐southern oscillation phases - Xiang Han; Haikun Zhao; Xun Li; Graciela B. Raga; Chao Wang; Qingqing Li (International Journal of Climatology, 2020)
The study of the interannual and intraseasonal modulation of tropical cyclogenesis (TCG) in the northwest Pacific (NWP) basin has received significant attention in the past. Most previous studies have focused on the individual impact of El Niño‐southern oscillation (ENSO) or Madden–Julian Oscillation on TCG, whereas the combined effect of ENSO and another leading intraseasonal oscillation mode, quasi‐biweekly oscillation (QBWO), on NWP TCG has rarely been studied. Therefore, this study systemically investigates the modulation of NWP TCG by the QBWO under different ENSO phases. A significant modulation of TCG by QBWO in the ENSO neutral years is observed, with significantly increased (decreased) TCG over the NWP in QBWO active (inactive) phases. Moreover, during El Niño years and La Niña years, the modulation of TCG by QBWO is not significant and no distinctive difference in the TCG frequency can be detected. Further analyses show that the modulation of TCG by the QBWO is mainly related to the changes in large‐scale environment and energy that affect TCG associated with active or inactive phases of the QBWO under different ENSO phases. Large‐scale environmental factors and energy are more favourable for TCG during ENSO neutral years compared with El Niño and La Niña years. These results are associated with QBWO cycle under the impact of background (e.g., boundary layer moisture and zonal wind shear) which is determined by ENSO conditions.

Bin-based genome-wide association analyses improve power and resolution in QTL mapping and identify favorable alleles from multiple parents in a four-way MAGIC rice population - Zhongmin Han; Gang Hu; Hua Liu; Famao Liang; Lin Yang; Hu Zhao; Qinghua Zhang; Zhixin Li; Qifa Zhang; Yongzhong Xing (Theoretical and Applied Genetics, 2020)

TRY plant trait database – enhanced coverage and open access - Jens Kattge; Gerhard Bönisch; Sandra Díaz; Sandra Lavorel; Iain Colin Prentice; Paul Leadley; Susanne Tautenhahn; Gijsbert D. A. Werner; Tuomas Aakala; Mehdi Abedi; Alicia T. R. Acosta; George C. Adamidis; et al. (Global Change Biology, 2020)
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.

Review of Chinese atmospheric science research over the past 70 years: Synoptic meteorology - Zhiyong Meng; Fuqing Zhang; Dehai Luo; Zhemin Tan; Juan Fang; Jianhua Sun; Xueshun Shen; Yunji Zhang; Shuguang Wang; Wei Han; Kun Zhao; Lei Zhu; et al. (Science China Earth Sciences, 2019)

The Rho kinase inhibitor fasudil attenuates Aβ1–42-induced apoptosis via the ASK1/JNK signal pathway in primary cultures of hippocampal neurons - Ye Gao; Yuqing Yan; Qingli Fang; Nianping Zhang; Gajendra Kumar; Jihong Zhang; Li-Juan Song; Jiezhong Yu; Linhu Zhao; Han-Ting Zhang; Cun-Gen Ma (Metabolic Brain Disease, 2019)

QTL analysis of main agronomic traits in rice under low temperature stress - Jianghong Tang; Xiaoding Ma; Di Cui; Bing Han; Leiyue Geng; Zhengwu Zhao; Yafei Li; Longzhi Han (Euphytica, 2019)

Interception of sulfate deposition from a closed canopy to a forest gap edge canopy in a subalpine dragon spruce plantation - Yu Zhang; Fu-zhong Wu; Bo Tan; Zhen-feng Xu; Han Li; Jun-cheng Liu; Hai-rong Zhao; Si-yi Tan; Cheng-ming You; Wan-qin Yang (Journal of Mountain Science, 2019)

Multi‐model analysis of climate impacts on plant photosynthesis in China during 2000–2015 - Hao Yan; Shao‐Qiang Wang; Jun‐Bang Wang; Yun Cao; Ling‐Ling Xu; Men‐Xin Wu; Lu Cheng; Liu‐Xi Mao; Feng‐Hua Zhao; Xian‐Zhou Zhang; Yun‐Fen Liu; Yan‐Fen Wang; et al. (International Journal of Climatology, 2019)
Differences, arising from differences in gross primary production (GPP) model structures and driving forces, have fuelled arguments concerning interannual changes of GPP in China since 2000. To better investigate the interannual variability of GPP and its covariance with climate factors in China, this study adopted a multi‐model analysis based on three GPP models (i.e., Terrestrial Ecosystem Carbon flux model [TEC], Breathing Earth System Simulator model [BESS], and MOD17 GPP model). The results show that annual GPP in China increased by 0.021–0.057 Pg C year −1 from 2000 to 2015 attributable to atmospheric‐CO 2 fertilization effects and favourable climate change, that is, increasing precipitation ( P r ) and temperature ( T a ). However, northern China and southern China had a large difference in the amplitude of these GPP changes; annual GPP increased by 0.017–0.039 Pg C year −1 in northern China but only 0.001–0.018 Pg C year −1 in southern China. Northern China and southern China occupy contrasting climate zones and this contrast produced different interannual variability of GPP through different mechanisms. Northern China has a dry climate with GPP changes sensitive to P r . As a result, more P r along with higher T a in northern China produced the strong uptrend of GPP from 2000 to 2015. In contrast, southern China has a wet climate with its GPP sensitive to solar radiation and T a . For the interval of 2000–2015, decreasing radiation plus drought exerted a negative influence on GPP in southern China. This study highlights the diverse mechanisms in which climate change affects GPP in dry and wet climate zones. A robust multi‐model analysis is preferred to reduce uncertainties arising from a single GPP model and its driving data.

Complete genome sequences of five prunus necrotic ringspot virus isolates from Inner Mongolia of China and comparison to other PNRSV isolates around the world - Shuang Song; Ping-ping Sun; Ya-han Chen; Qiang Ma; Xiao-yun Wang; Ming-min Zhao; Zheng-nan Li (Journal of Plant Pathology, 2019)

Optimization and mechanisms of biosorption process of Zn(II) on rape straw powders in aqueous solution - Xin Liu; Bin Han; Chun-li Su; Qin Han; Ke-jie Chen; Zhao-qiong Chen (Environmental Science and Pollution Research, 2019)

Three Camellia sinensis glutathione S-transferases are involved in the storage of anthocyanins, flavonols, and proanthocyanidins - Yajun Liu; Han Jiang; Yue Zhao; Xin Li; Xinlong Dai; Juhua Zhuang; Mengqing Zhu; Xiaolan Jiang; Peiqiang Wang; Liping Gao; Tao Xia (Planta, 2019)

The co-segregation of the MYL2 R58Q mutation in Chinese hypertrophic cardiomyopathy family and its pathological effect on cardiomyopathy disarray - Kunlun Yin; Yi Ma; Hao Cui; Yang Sun; Bianmei Han; Xuewen Liu; Kun Zhao; Wenke Li; Jingjin Wang; Hongyue Wang; Shuiyun Wang; Zhou Zhou (Molecular Genetics and Genomics, 2019)

Re-examining the role of ventral tegmental area dopaminergic neurons in motor activity and reinforcement by chemogenetic and optogenetic manipulation in mice - Man-Yi Jing; Xiao Han; Tai-Yun Zhao; Zhi-Yuan Wang; Guan-Yi Lu; Ning Wu; Rui Song; Jin Li (Metabolic Brain Disease, 2019)

Visualization of Turbot (Scophthalmus maximus) Primordial Germ Cells in vivo Using Fluorescent Protein Mediated by the 3′ Untranslated Region of nanos3 or vasa Gene - Li Zhou; Xueying Wang; Qinghua Liu; Shihong Xu; Haixia Zhao; Mingming Han; Yunong Wang; Zongcheng Song; Jun Li (Marine Biotechnology, 2019)

Open shear fractures at depth in anticlines: insights from the Kuqa foreland thrust belt, Tarim Basin - Zhao Wang; Xiuxiang Lv; Ying Li; Wenwen Qian; Shanshan Hu; Xiaoxiao Zhou; Han Quan (International Journal of Earth Sciences, 2019)

MdHIR4 transcription and translation levels associated with disease in apple are regulated by MdWRKY31 - Xian-Yan Zhao; Chen-Hui Qi; Han Jiang; Ming-Shuang Zhong; Chun-Xiang You; Yuan-Yuan Li; Yu-Jin Hao (Plant Molecular Biology, 2019)

Integrated analysis of RNA-seq and microRNA-seq depicts miRNA–mRNA networks involved in stripe patterns of Botia superciliaris skin - Jian Zhou; Han Zhao; Lu Zhang; Can Liu; Siyuan Feng; Jideng Ma; Qiang Li; Hongyu Ke; Xinyu Wang; Lingyan Liu; Chao Liu; Xutao Su; et al. (Functional & Integrative Genomics, 2019)

Development of a loop-mediated isothermal amplification for rapid diagnosis of Aphelenchoides ritzemabosi - Dong-Wei Wang; Chun-Ling Xu; Zong-Shi Bai; Jun-Yi Li; Yu-Chun Han; Li-Rong Zhao; Hui Xie (European Journal of Plant Pathology, 2019)