Flood variability in the upper Yangtze River over the last millennium—Insights from a comparison of climate-hydrological model simulated and reconstruction - Ran Huo; Hua Chen; Lu Li; Chong-Yu Xu; Jingjing Li; Si Hong; Chesheng Zhan; Jun Xia (Science China Earth Sciences, 2023)

Involvement of purinergic P2Y1R in antidepressant-like effects of electroacupuncture treatment on social isolation stress mice - Lingling Yu; Yao Wang; Hong Zhang; Man Li; Guang Chen; Jiahuan Hao; Minjie Xie (Purinergic Signalling, 2023)

Insights on the stem elongation of spur-type bud sport mutant of ‘Red Delicious’ apple - Wen-Fang Li; Zong-Huan Ma; Zhi-Gang Guo; Cun-Wu Zuo; Ming-Yu Chu; Juan Mao; Bai-Hong Chen (Planta, 2023)

PUM2 aggravates the neuroinflammation and brain damage induced by ischemia–reperfusion through the SLC7A11-dependent inhibition of ferroptosis via suppressing the SIRT1 - Qingran Liu; Yongchang Liu; Yan Li; Zhen Hong; Shaoquan Li; Chen Liu (Molecular and Cellular Biochemistry, 2023)
Cerebral ischemia–reperfusion (I/R) injury occurs due to the restoration of blood perfusion after cerebral ischemia, which results in the damage of the brain structures and functions. Unfortunately, currently there are no effective methods for preventing and treating it. The pumilio 2 (PUM2) is a type of RBPs that has been reported to participate in the progression of several diseases. Ferroptosis is reported to be involved in I/R injury. Whether PUM2 modulated I/R injury through regulating ferroptosis remains to be elucidated. The cerebral I/R models including animal middle cerebral artery occlusion/reperfusion (MCAO/R) model and oxygen–glucose deprivation/reperfusion (OGD/R)-induced cortical neuron injury cell model of were established and, respectively. RT-qPCR was applied for evaluating PUM2, SIRT1 and SLC7A11 expression. Western blot was employed for measuring the protein expression levels. The viability of cortical neurons was tested by MTT assay. The histological damage of the brain tissues was assessed by H&E staining. The level of PUM2 was boosted in both the brain tissues of the MCAO model and OGD/R-induced cortical neuron injury model. Silence of PUM2 alleviated MCAO-induced brain injury and decreased the death of PC12 cell exposed to OGD/R. PUM2 also aggravated the accumulation of free iron in MCAO mice and OGD/R-induced cortical neuron injury model. In addition, PUM2 suppressed SLC7A11 via inhibiting expression of SIRT1. Rescue assays unveiled that downregulation of SLC7A11 reversed PUM2 mediated neuroinflammation and brain damage induced by I/R. PUM2 aggravated I/R-induced neuroinflammation and brain damage through the SLC7A11-dependent inhibition of ferroptosis by suppressing SIRT1, highlighting the role of PUM2 in preventing or treating cerebral I/R injury.

Exploring the potential anti-Alzheimer disease mechanisms of Alpiniae Oxyphyliae Fructus by network pharmacology study and molecular docking - Rong-Rong Zhen; Yan-Jie Qu; Li-Min Zhang; Chao Gu; Min-Rui Ding; Lei Chen; Xiao Peng; Bing Hu; Hong-Mei An (Metabolic Brain Disease, 2023)

Prediction and significance of intra-platform shoals distribution of Changxing formation in Gaoshiti area of Sichuan Basin - Dong Wang; Hong Liu; Tong Yu; Minglong Li; Lei Tan; Kun Zhang; Chao Geng; Cong Chen (Carbonates and Evaporites, 2023)

Empirical seismic vulnerability assessment model of typical urban buildings - Si-Qi Li; Yong-Sheng Chen; Hong-Bo Liu; Carlo Del Gaudio (Bulletin of Earthquake Engineering, 2023)

Coexposure to multiple metals and renal tubular damage: a population-based cross-sectional study in China’s rural regions - JingJing Quan; Yan Li; Minxue Shen; Yao Lu; Hong Yuan; Bin Yi; Xiang Chen; Zhijun Huang (Environmental Science and Pollution Research, 2023)

Recent advances in application of heterogeneous electro-Fenton catalysts for degrading organic contaminants in water - Wenjing Chen; Danlian Huang; Cui Lai; Yukui Fu; Wenfang Chen; Haoyang Ye; Huan Yi; Bisheng Li; Ling Li; Fanzhi Qin; Hong Qin; Lei Qin (Environmental Science and Pollution Research, 2023)

High-resolution distribution and emission of dimethyl sulfide and its relationship with pCO2 in the Northwest Pacific Ocean - Shi-Bo Yan; Xiao-Jun Li; Feng Xu; Hong-Hai Zhang; Jian Wang; Yueqi Zhang; Gui-Peng Yang; Guang-Chao Zhuang; Zhaohui Chen (Frontiers in Marine Science, 2023)
Ocean-derived dimethyl sulfide (DMS) is widely concerning because of its hypothesized influence on global climate change. This study aims to explore the distribution characteristics and influencing factors of DMS and partial pressure of carbon dioxide ( p CO 2 ) in the Northwest Pacific Ocean, as well as the potential relationship between DMS and p CO 2 . A high-resolution, underway, shipboard measurement device was used to determine the DMS and p CO 2 of the surface seawater and atmosphere in the Northwest Pacific and its marginal seas during November 2019. The result show that atmospheric and surface seawater DMS concentrations ranged from 3 to 125 pptv and 0.63 to 2.28 nmol L -1 , respectively, with mean values of 46 ± 19 pptv and 1.08 ± 0.34 nmol L -1 . The average sea surface p CO 2 was 371 ± 16 μatm (range from 332 to 401 μatm). The trends in the surface seawater DMS in different current systems were primarily associated with phytoplankton abundance and composition. Biological activity and physical processes such as cooling jointly influenced the sea surface p CO 2 . A cold eddy along the transect in the Northwest Pacific Ocean increased DMS at the sea surface by 10% and CO 2 uptake by 3%. We found a significant negative correlation between DMS and p CO 2 in the Northwest Pacific Ocean at the 0.1° resolution [DMS] seawater = -0.0161[ p CO 2 ] seawater + 7.046 (R 2 = 0.569, P < 0.01). The DMS and p CO 2 sea-air fluxes were estimated to range from 0.04 to 25.3 μmol m -2 ·d -1 and from -27.0 to 4.22 mmol m -2 ·d -1 throughout the survey area. The Northwest Pacific Ocean, especially the Oyashio Current, is an important sink of CO 2 and a source of DMS.

The study on the main mode of the death of red blood cells in grass carp (Ctenopharyngodon idella) - Hong Chen; Minshan Yao; Ying Tang; Lixiang Wei; Junyan Lin; Fei Shi; Fanbin Zhan; Yanan Li; Jun Li; Li Lin; Zhendong Qin (Aquaculture, 2023)

Study on the regulatory mechanism of erythropoietin in erythropoiesis in grass carp (Ctenopharyngodon idella) - Junyan Lin; Lixiang Wei; Minshan Yao; Hong Chen; Ying Tang; Fei Shi; Fanbin Zhan; Yanan Li; Jun Li; Li Lin; Zhendong Qin (Aquaculture, 2023)

Molecular mechanism of di-n-butyl phthalate promotion of bladder cancer development - En-Hui Li; Bai-Hui Xu; Hai-Bin Wei; Yu-Chen Bai; Qi Zhang; Wei-Wen Yu; Zhi-Hui Xu; Xiao-Long Qi; Da-Hong Zhang; Heng Wang (Toxicology in Vitro, 2023)

Roles of substrates in removing antibiotics and antibiotic resistance genes in constructed wetlands: A review - Erping Cui; Zhenchao Zhou; Feng Gao; Hong Chen; Jianan Li (Science of The Total Environment, 2023)

Pollution mechanisms and photochemical effects of atmospheric HCHO in a coastal city of southeast China - Taotao Liu; Yiling Lin; Jinsheng Chen; Gaojie Chen; Chen Yang; Lingling Xu; Mengren Li; Xiaolong Fan; Fuwang Zhang; Youwei Hong (Science of The Total Environment, 2023)

Increases in ozone-related mortality in China over 2013–2030 attributed to historical ozone deterioration and future population aging - Lei Chen; Hong Liao; Jia Zhu; Ke Li; Yang Bai; Xu Yue; Yang Yang; Jianlin Hu; Meigen Zhang (Science of The Total Environment, 2023)

Food provisioning results in functional, but not compositional, convergence of the gut microbiomes of two wild Rhinopithecus species: Evidence of functional redundancy in the gut microbiome - Hong Li; Wancai Xia; Xingyu Liu; Xueyu Wang; Guoqi Liu; Hua Chen; Lifeng Zhu; Dayong Li (Science of The Total Environment, 2023)

ARSCP: An antimicrobial residue surveillance cloud platform for animal-derived foods - Jun-Jun Yu; Ya-Lin Hu; Cheng-Zheng Liu; Shuai-Bin Wu; Zi-Jian Zheng; Ze-Hua Cui; Li Chen; Tian Wei; Shi-Kai Sun; Jun Ning; Xiang Wen; Qiu-Yue Diao; et al. (Science of The Total Environment, 2023)

Will residents’ energy-conservation behavior be continued under perception of behavior outcome? The moderating role of attribution style - Ting Yue; Mengting Li; Qianru Wang; Ruyin Long; Hong Chen; Junli Liu; Feiyu Chen (Resources, Conservation and Recycling, 2023)

Coumaronochromones, flavanones, and isoflavones from the twigs and leaves of Erythrina subumbrans inhibit PTP1B and nitric oxide production - Cai-Ying Liu; Pan Deng; Bin Wang; Ai-Hong Liu; Meng-Ge Wang; Song-Wei Li; Li-Li Chen; Shui-Chun Mao (Phytochemistry, 2023)

A new phragmalin-type limonoid from the roots of Trichilia sinensis - Shou-Bai Liu; Jin-Ling Yang; Hui-Qin Chen; Cheng-min Yang; Hao Wang; Cai-Hong Cai; Jing-Zhe Yuan; Wen-Li Mei; Hao-Fu Dai (Phytochemistry Letters, 2023)

2000 years of lake-level fluctuations and human adaptation around China's largest freshwater lake - Huanye Wang; Weiguo Liu; Qin Leng; Lin Yang; Hui Zhao; Jun Yang; Yuwei Chen; Shangbin Xiao; Yunning Cao; Jing Hu; Xiaoke Qiang; Peng Cheng; et al. (Palaeogeography, Palaeoclimatology, Palaeoecology, 2023)

Complete genome sequence of marine Roseobacter lineage member Ruegeria sp. YS9 with five plasmids isolated from red algae - Qun-Jian Yin; Fang-Chao Zhu; Hong-Zhi Tang; Xu-Yang Chen; Xin Liu; Li-Chang Tang; Xue-Gong Li (Marine Genomics, 2023)

Inhibition and recovery of UASB-Anammox process: Performance characteristics and microbial community dynamics in response to substrate concentration and dissolved oxygen exposure - Hong Wang; Hong Chen; Shiyu Liu; Lei Li; Donghai Yang; Xiaohu Dai (Journal of Water Process Engineering, 2023)

Amorphous SnO2 decorated ZnSn(OH)6 promotes interfacial hydroxyl polarization for deep photocatalytic toluene mineralization - Lvcun Chen; Kanglu Li; Yan Yang; Ting Xue; Hong Wang; Ben Lei; Jianping Sheng; Fan Dong; Yanjuan Sun (Journal of Hazardous Materials, 2023)

Risks of applying mobilising agents for remediation of arsenic-contaminated soils: Effects of dithionite–EDTA and citric acid on arsenic fractionation, leachability, oral bioavailability/bioaccessibility and speciation - Xiao-Chen Chen; Cong-Cong Yao; Ao Wang; Zeng-Di Zhang; Long-Zhao Chen; Jian-Yu Zhang; Xian-Hua Liu; Hong-Bo Li (Journal of Hazardous Materials, 2023)

Applications of functional nanoparticle–stabilized surfactant foam in petroleum-contaminated soil remediation - Jia Liu; Wen-yan Li; Hong-xin Chen; Shuang-qiang Li; Li-heng Yang; Kai-ming Peng; Chen Cai; Xiang-feng Huang (Journal of Hazardous Materials, 2023)

Coupled effects of environmental conditions on the spatio-temporal variability of phytoplankton in canyon-shaped reservoirs - Ning Liao; Hong Li; Linglei Zhang; Min Chen; Jia Li; Lihua You (Journal of Cleaner Production, 2023)

Peroxymonosulfate activation for effective atrazine degradation over a 3D cobalt-MOF: Performance and mechanism - Ya Li; Fei Wang; Xueying Ren; Peng Wang; Fu-Xue Wang; Hong-Yu Chu; Shijie Gao; Chong-Chen Wang (Journal of Environmental Chemical Engineering, 2023)

Unsupervised classification of polarimetric SAR images via SV G p 0 MM with extended variational inference - Ze-Chen Li; Heng-Chao Li; Gui Gao; Ze-Xi Hua; Fan Zhang; Wen Hong (ISPRS Journal of Photogrammetry and Remote Sensing, 2023)

Effect of concentration of nickel precursor on the synthesis of Ni phyllosilicate for CO2 methanation: The promotion of supersaturation - Qinzhen Fan; Hai Li; Hong Chen; Lihua Cheng; Qing Liu (Fuel, 2023)

Efficient liquefaction of Kraft lignin over N-doped carbon supported size-controlled MoC nanoparticles in supercritical ethanol - Chang Li; Hong Li; Yishuang Wang; Zhiyuan Tang; Jingjing Shi; Mingqiang Chen (Fuel, 2023)

Selective catalytic depolymerization of lignin to guaiacols over Mo-Mn/sepiolite in supercritical ethanol - Mingqiang Chen; Wei Dai; Yishuang Wang; Zhiyuan Tang; Hong Li; Chang Li; Zhonglian Yang; Jun Wang (Fuel, 2023)

Hyperspectral imaging combined with chemometrics for rapid detection of talcum powder adulterated in wheat flour - Hong-Ju He; Yan Chen; Guanglei Li; Yuling Wang; Xingqi Ou; Jingli Guo (Food Control, 2023)

6His-tatritin promotes antimicrobial defense via regulating immune ability and intestinal microbial community in grass carp (Ctenopharyngodon idella) - Wei-Feng Wang; Chu-Xing Cheng; Hong Liu; Xiu-Li Chen; Huan-Ling Wang (Fish & Shellfish Immunology, 2023)

IFI44L as a novel epigenetic silencing tumor suppressor promotes apoptosis through JAK/STAT1 pathway during lung carcinogenesis - Yong Zeng; Hong-qiang Chen; Zhe Zhang; Jun Fan; Jing-zhi Li; Shi-meng Zhou; Na Wang; Su-peng Yan; Jia Cao; Jin-yi Liu; Zi-yuan Zhou; Wen-bin Liu (Environmental Pollution, 2023)

Towards next generation design of sustainable, durable, multi-hazard resistant, resilient, and smart civil engineering structures - Hong Hao; Kaiming Bi; Wensu Chen; Thong M. Pham; Jun Li (Engineering Structures, 2023)

Socio-econ-ecosystem multipurpose simulator (SEEMS): An easy-to-apply agent-based model for simulating small-scale coupled human and nature systems in biological conservation hotspots - Yufeng Chen; Liyan Xu; Xiao Zhang; Zilin Wang; Hailong Li; Yansheng Yang; Hong You; Dihua Li (Ecological Modelling, 2023)

UV pretreatment reduced biofouling of ultrafiltration and controlled opportunistic pathogens in secondary water supply systems - Haibo Wang; Haotian Hu; Susu Chen; Cory Schwarz; Hong Yin; Chisheng Hu; Guiwei Li; Baoyou Shi; Jingang Huang (Desalination, 2023)

Integrated adsorption and photodegradation of tetracycline by bismuth oxycarbonate/biochar nanocomposites - Yidan Luo; Aofeng Zheng; Junda Li; Yu Han; Mingshan Xue; Longshuai Zhang; Zuozhu Yin; Chan Xie; Zhi Chen; Li Ji; Zhen Hong; Xianchuan Xie (Chemical Engineering Journal, 2023)

Mimicking the competitive interactions to reduce resistance induction in antibacterial actions - Shuo Zhao; Zheyu Li; Suyao Yin; Qi-dai Chen; Hong-bo Sun; Liping Wen; Lei Jiang; Kai Sun (Chemical Engineering Journal, 2023)

The construction of conjugated organic polymers containing phenanthrenequinone redox centers for visible-light-driven H2O2 production from H2O and O2 without any additives - Xiahong Xu; Hong Zhong; Wei Huang; Yan Sui; Rongjian Sa; Wentong Chen; Gangyong Zhou; Xiaodan Li; Duofu Li; Meicheng Wen; Bo Jiang (Chemical Engineering Journal, 2023)

Photodynamic amplified immune checkpoint-blockade therapy of self-delivery bioregulator via epigenetic reprogramming - Linping Zhao; Chuyu Huang; Rongrong Zheng; Xiaona Rao; Renjiang Kong; Runtian Guan; Zuxiao Chen; Xiyong Yu; Hong Cheng; Shiying Li (Chemical Engineering Journal, 2023)

Photocurable liquid crystal hydrogels with different chargeability and tunable viscoelasticity based on chitin whiskers - Jingsheng Chen; Zelin Zhu; Jiaqing Chen; Yiting Luo; Lin Li; Kun Liu; Shan Ding; Hong Li; Mingxian Liu; Changren Zhou; Binghong Luo (Carbohydrate Polymers, 2023)

Potential for volatile fatty acid production via anaerobically-fermenting rice straw pretreated with silage effluent and phenyllactic acid - Hong Sun; Chaosheng Liao; Liangyin Chen; Qiming Cheng; Yulong Zheng; Chunmei Wang; Yixiao Xie; Chao Chen; Ping Li (Bioresource Technology, 2023)

Chronic hypoxia and Cu2+ exposure induce gill remodeling of largemouth bass through endoplasmic reticulum stress, mitochondrial damage and apoptosis - Qiao Liu; Hong Wang; Jiayu Ge; Lisen Li; Jie Luo; Kuo He; Haoxiao Yan; Xin Zhang; Rabia Tahir; Wei Luo; Shiyi Chen; Zhang Cheng; et al. (Aquatic Toxicology, 2023)

Different roles of primary and secondary sources in reducing PM2.5: Insights from molecular markers in Pearl River Delta, South China - Kong Yang; Duo-Hong Chen; Xiang Ding; Jun Li; Yu-Qing Zhang; Tao Zhang; Qiao-Yun Wang; Jun-Qi Wang; Qian Cheng; Hao Jiang; Ping Liu; Zi-Rui Wang; et al. (Atmospheric Environment, 2023)

A glyoxylate-containing benzene derivative and butenolides from a marine algicolous fungus Aspergillus sp. SCSIO 41304 - Xin Qi; Wei-Hao Chen; Xiu-Ping Lin; Sheng-Rong Liao; Bin Yang; Xue-Feng Zhou; Yong-Hong Liu; Jun-Feng Wang; Yong Li (Natural Product Research, 2023)

Draft genome of the medicinal tea tree Melaleuca alternifolia - Xiaoning Zhang; Silin Chen; Ye Zhang; Yufei Xiao; Yufeng Qin; Qing Li; Li Liu; Buming Liu; Ling Chai; Hong Yang; Hailong Liu (Molecular Biology Reports, 2023)

Correction to: Microplastic pollution and its impact on marine microbes in Zhanjiang, China - Qing-Lang Song; Fang-Hong Nie; Di-Hua Zhu; Yun-Li Wei; Min Zhang; Yao Hu; Meng-Meng Chen; Dan-Ju Kang; Zhi-Bao Chen; Hong-Ying Lin; Jin-Jun Chen (Journal of Coastal Conservation, 2023)

Screening of nanobody targeting alkaline phosphatase PhoX in Microcystis and detection of the PhoX in situ by fluorescence immunoassays - Yao Zu; Sujuan Hong; Congcong Yin; Yu Luo; Chen Xu; Jianhong Li (Journal of Applied Phycology, 2023)

Maltol ameliorates intervertebral disc degeneration through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3 inflammasome-mediated pyroptosis - Yuhang Gong; Jianxing Qiu; Ting Jiang; Ze Li; Weikang Zhang; Xiaohang Zheng; Zixuan He; Weifu Chen; Zhangfu Wang; Xingbing Feng; Meizhen Wang; Zhenghua Hong (Inflammopharmacology, 2023)
Objectives As one of the major causes of low back pain, intervertebral disc degeneration (IDD) has caused a huge problem for humans. Increasing evidence indicates that NLRP3 inflammasome-mediated pyroptosis of NP cells displays an important role in the progression of IDD. Maltol (MA) is a flavoring agent extracted from red ginseng. Due to its anti-inflammatory and antioxidant effects, MA has been widely considered by researchers. Therefore, we hypothesized that MA may be a potential IVD protective agent by regulating NP cells and their surrounding microenvironment. Methods In vitro, qRT-PCR, and Western blot were used to explore the effect of MA on the transcription and protein expression of the anabolic protein (ADAMTS5, MMP3, MMP9) catabolic protein (Aggrecan), and pro-inflammatory factor (iNOS COX-2). Next, the effects of MA on PI3K/AKT/NF-κB pathway and pyroptosis pathway were analyzed by Western blot and immunofluorescence. Molecular docking was used to investigate the relationship between PI3K and MA. Moreover, ELISA was also used to detect the effects of MA on inflammatory factors (TNF-α, PGE2, IL-1β, and IL-18). In vivo, the effects of MA on the vertebral structure of IDD mice were studied by HE and SO staining and the effects of MA on ECM and PI3K/AKT/NF-κB and pyroptosis pathway of IDD mice were studied by immunohistochemical staining. Results MA can ameliorate intervertebral disc degeneration in vivo and in vitro. Specifically, the molecular docking results showed that the binding degree of MA and PI3K was significant. Second, in vitro studies showed that MA inhibited the degradation of ECM and inflammatory response by inhibiting the PI3K/AKT/NF-κB pathway and the pyroptosis mediated by NLRP3 inflammasome, which increased the expression of anabolic proteins, decreased the expression of catabolic proteins, and decreased the secretion of inflammatory mediators such as IL-18 and IL-1β. In addition, according to the study results of the mouse lumbar instability model, MA also improved the tissue disorder and degradation of the intervertebral disc, reduced the loss of proteoglycan and glycosaminoglycan, and inhibited intervertebral disc inflammation, indicating that MA has a protective effect on the intervertebral disc to intervertebral disc in mice. Conclusions Our results suggest that MA slowed IDD development through the PI3K/AKT/NF-κB signaling pathway and NLRP3 inflammasome-mediated pyroptosis, indicating that MA appeared to be a viable medication for IDD treatment.

Portal vein tumor thrombosis in hepatocellular carcinoma: molecular mechanism and therapy - Xing-Hao Zhou; Jing-Ru Li; Tang-Hui Zheng; Hong Chen; Chen Cai; Sheng-Long Ye; Bo Gao; Tong-Chun Xue (Clinical & Experimental Metastasis, 2023)

The age of onset and cognitive impairment at the early stage of schizophrenia - Yi Yin; Shuangshuang Li; Jinghui Tong; Junchao Huang; Baopeng Tian; Song Chen; Yimin Cui; Shuping Tan; Zhiren Wang; Fude Yang; Yongsheng Tong; L. Elliot Hong; et al. (Cognitive Neurodynamics, 2023)

Porewater dissolved inorganic carbon released due to artificial sediment scouring in the Yellow River - Xing-yu Huang; Dong Zhang; Fu-shun Wang; Zhi-qi Zhao; Ai-chun Chen; Jun-wen Zhang; Cong Zhang; Li Wu; Yu-hong Li; Bing-juan Ma; Qi-yan Feng (Applied Geochemistry, 2023)

Detection and genetic analysis of porcine circovirus-like virus in pigs with diarrhea between 2016 and 2021 in Henan and Shanxi provinces of China - Liu-Hui Zhang; Lin-Qing Wang; Hong-Xuan Li; Hong-Lei Zhang; Lan-Lan Zheng; Xi-Meng Chen; Hong-Ying Chen (Archives of Virology, 2023)

Proactive therapeutic drug monitoring of vincristine in pediatric and adult cancer patients: current supporting evidence and future efforts - Chun-Ying Wu; Guan-Ting Li; Chen-Chao Chu; Hong-Li Guo; Wei-Rong Fang; Tao Li; Yong-Ren Wang; Jing Xu; Ya-Hui Hu; Li Zhou; Feng Chen (Archives of Toxicology, 2023)

Atopomonas sediminilitoris sp. nov., isolated from beach sediment of Zhairuo Island, China - Kejing Li; Zhenbo Ye; Gen Chen; Kaiwen Zheng; Jun Yin; Sanjit Chandra Debnath; Cen Yan; Yi Hong; Zhen Guo; Pinmei Wang; Fabai Wu; Daoqiong Zheng (Antonie van Leeuwenhoek, 2023)

Retraction Note: Cancer-derived exosomal miR-221-3p promotes angiogenesis by targeting THBS2 in cervical squamous cell carcinoma - Xiang-Guang Wu; Chen-Fei Zhou; Yan-Mei Zhang; Rui-Ming Yan; Wen-Fei Wei; Xiao-Jing Chen; Hong-Yan Yi; Luo-Jiao Liang; Liang-sheng Fan; Li Liang; Sha Wu; Wei Wang (Angiogenesis, 2023)

Correction: A novel lymphatic pattern promotes metastasis of cervical cancer in a hypoxic tumour-associated macrophage-dependent manner - Xiao-Jing Chen; Wen-Fei Wei; Zi-Ci Wang; Nisha Wang; Chu-Hong Guo; Chen-Fei Zhou; Luo-Jiao Liang; Sha Wu; Li Liang; Wei Wang (Angiogenesis, 2023)

Twenty years of ocean observations with China Argo - Zenghong Liu; Xiaogang Xing; Zhaohui Chen; Shaolei Lu; Xiaofen Wu; Hong Li; Chunling Zhang; Lijing Cheng; Zhaoqin Li; Chaohui Sun; Jianping Xu; Dake Chen; et al. (Acta Oceanologica Sinica, 2023)

Irrigation scheduling of pressurized irrigation networks for minimizing energy consumption - Yiyuan Pang; Hong Li; Pan Tang; Chao Chen (Irrigation and Drainage, 2023)
Although pressurized irrigation systems can increase water use efficiency, the energy requirements of these irrigation systems are much higher than those of gravity‐fed systems in water transport and distribution. To reduce irrigation energy consumption, this research introduces two factors influencing energy consumption: branch pipe assigned queue and branch pipe assigned times. The traditional single water distribution and sequential queue are optimized as multiple water distributions and stochastic queues. Combined with traditional motor frequency optimization, eight scheduling scenarios are established based on these three optimization factors and compared with the original scenario. Next, this study optimizes the discharge of all hydrants for each scenario using a genetic algorithm with the same framework and operational process. Predictions and experiments in a case study in eastern China indicated that only optimizing the branch pipe assigned queue or times cannot significantly reduce energy consumption, while an energy‐savings rate of 8% can be achieved by simultaneously optimizing the branch pipe assigned queue and times. In addition, the energy savings rate of only optimizing the motor operating frequency is 11%. However, an energy‐saving rate of 19% can be obtained by combining branch pipe‐assigned times optimization with motor frequency optimization.

This is what we know: Assessing the stock status of the data-poor skipjack tuna (Katsuwonus pelamis) fishery in the South China Sea - Kui Zhang; Jun Zhang; Peng Zhang; Li Su; Xiaofan Hong; Yongsong Qiu; Zuozhi Chen (Frontiers in Marine Science, 2023)
Skipjack tuna ( Katsuwonus pelamis ) is a highly migratory species of significant value in global marine fisheries. The South China Sea (SCS) is the largest marginal sea in the northwestern Pacific Ocean, and many tuna and tuna-like species occur within it. Although a recent Western and Central Pacific Fisheries Commission report identified skipjack tuna in the western and central Pacific to be sustainably fished, the exploitation status of skipjack tuna in the SCS is still unclear, due to limited data. We apply two data-poor methods, length-based Bayesian biomass estimation (LBB) and length-based spawning potential ratio (LBSPR), to assess the status of skipjack tuna stock in the SCS. We use electronic length frequency analysis to estimate von Bertalanffy growth parameters (asymptotic length L inf and growth coefficient K ) to serve as priors for LBB and LBSPR estimation. Estimates are calculated for SCS skipjack tuna L inf (68.3 cm), K (0.325 year −1 ), natural mortality (0.49 year −1 ) and mean fork length at 50% sexual maturity (36.7 cm). LBB analysis reveals the estimated relative stock size (0.29) indicates that the SCS skipjack tuna stock maybe heavily overfished. LBSPR analysis reveals the estimated spawning potential ratio for this fishery to be 3%, which is significantly below the limit reference point of 20%. Accordingly, for the SCS skipjack tuna stock we identify a need to reduce fishing mortality by controlling fishing effort and increasing catchable size.

Personalizing atomoxetine dosing in children with ADHD: what can we learn from current supporting evidence - Di Fu; Hong-Li Guo; Ya-Hui Hu; Wei-Rong Fang; Qian-Qi Liu; Jing Xu; Dan-Dan Wu; Feng Chen (European Journal of Clinical Pharmacology, 2023)

Associations between long-term exposure to ambient fine particulate pollution with the decline of kidney function and hyperuricemia: a longitudinal cohort study - Li-Kun Hu; Yu-Hong Liu; Kun Yang; Ning Chen; Lin-Lin Ma; Yu-Xiang Yan (Environmental Science and Pollution Research, 2023)

Efficient removal of uranium(VI) from aqueous solution by a novel phosphate-modified biochar supporting zero-valent iron composite - Ziwei Tang; Zhongran Dai; Mi Gong; Hong Chen; Xiayu Zhou; Yating Wang; Cong Jiang; Wanying Yu; Le Li (Environmental Science and Pollution Research, 2023)

TET1 involved in bisphenol A induced TM3 Leydig cell toxicity by regulating Cav3.3 hydroxymethylation - Shi-meng Zhou; Wen-bo Yuan; Jing-zhi Li; Hong-qiang Chen; Yong Zeng; Na Wang; Jun Fan; Zhe Zhang; Yuanyuan Xu; Jia Cao; Wen-bin Liu (Chemosphere, 2023)

Prenatal titanium exposure and child neurodevelopment at 1 year of age: A longitudinal prospective birth cohort study - Yangqian Jiang; Yongyue Wei; Wenhui Guo; Jiangbo Du; Tao Jiang; Hongxia Ma; Guangfu Jin; Ting Chen; Rui Qin; Shiyao Tao; Qun Lu; Hong Lv; et al. (Chemosphere, 2023)

Temperature-regulated and starvation-induced refractory para-toluic acid anaerobic biotransformation - Xiao-chen Ma; Ke Wang; Xin-lei Gao; Xiang-kun Li; Gai-ge Liu; Hong-ying Chen; Chen-yu Piao; Shi-jie You (Chemosphere, 2023)

Co-exposure to phenols and phthalates during pregnancy with the difference of body size in twins at one month old - Hong Mei; Langjing Deng; Jinying Xie; Xiaojie Li; Nanxin Wu; Liqin Hu; Guangtong Huang; Fanyu Mo; Da Chen; Han Xiao; Pan Yang (Chemosphere, 2023)

Immobilization of heavy metals in ceramsite prepared using contaminated soils: Effectiveness and potential mechanisms - Chengming Li; Bing Song; Zhiliang Chen; Zequan Liu; Lei Yu; ZeJian Zhi; Yan Zhao; Hong Wei; Min Song (Chemosphere, 2023)

Identification of sex-linked marker and candidate sex determination gene in ornamental fish, African scat (Scatophagus tetracanthus) - You-Xing Peng; Yuan-Qing Huang; Jian Zhong; Zheng-Ting Jiang; Sen Fan; Hong-Juan Shi; Hua-Pu Chen; Si-Ping Deng; Guang-Li Li; Dong-Neng Jiang (Aquaculture, 2023)

Large-scale testing of the mortise and tenon joint performance of the tunnel lining of prefabricated frame tunnels - Zhen Huang; Hai-wen Bai; Shao-kun Ma; Jia-wei Zhang; Yi-miao Chen; Hong-zhou Li (Tunnelling and Underground Space Technology, 2023)

Landslide-impacted soils recover faster biologically than chemically or physically, though recovery also varies with forest type in subtropical China - Jian Li; Lan Xiao; Jonathan D. Bakker; Qinghu Luo; Hang Yu; Jianzhao Wu; Songyang Li; Loretta Pedersen; Can Chen; Tao Hong; Han Lin; Daojie Wang; et al. (Soil and Tillage Research, 2023)

Formation pathways, gas-solid partitioning, and reaction kinetics of PCDD/Fs associated with baghouse filters operated at high temperatures: A case study - Xiaoqing Lin; Xiaoxiao Wang; Yuxuan Ying; Angjian Wu; Zhiliang Chen; Lei Wang; Hong Yu; Hao Zhang; Aizhong Ruan; Xiaodong Li; Jianhua Yan (Science of The Total Environment, 2023)

A critical review on microbial ecology in the novel biological nitrogen removal process: Dynamic balance of complex functional microbes for nitrogen removal - Hong Chen; Ke Liu; Enzhe Yang; Jing Chen; Yanling Gu; Sha Wu; Min Yang; Hong Wang; Dongbo Wang; Hailong Li (Science of The Total Environment, 2023)

Mapping Chinese annual gross primary productivity with eddy covariance measurements and machine learning - Xian-Jin Zhu; Gui-Rui Yu; Zhi Chen; Wei-Kang Zhang; Lang Han; Qiu-Feng Wang; Shi-Ping Chen; Shao-Min Liu; Hui-Min Wang; Jun-Hua Yan; Jun-Lei Tan; Fa-Wei Zhang; et al. (Science of The Total Environment, 2023)

Charge instability of topological Fermi arcs in chiral crystal CoSi - Zhicheng Rao; Quanxin Hu; Shangjie Tian; Qing Qu; Congrun Chen; Shunye Gao; Zhenyu Yuan; Cenyao Tang; Wenhui Fan; Jierui Huang; Yaobo Huang; Li Wang; et al. (Science Bulletin, 2023)

Paddy rice methane emissions across Monsoon Asia - Zutao Ouyang; Robert B. Jackson; Gavin McNicol; Etienne Fluet-Chouinard; Benjamin R.K. Runkle; Dario Papale; Sara H. Knox; Sarah Cooley; Kyle B. Delwiche; Sarah Feron; Jeremy Andrew Irvin; Avni Malhotra; et al. (Remote Sensing of Environment, 2023)

Physiological and transcriptomic analysis reveals the postharvest ripening differences between “Nantianhuang” and “Brazilian” banana fruit - Jiao Chen; Yixing Li; Fenfang Li; Debao Yuan; Keqian Hong (Postharvest Biology and Technology, 2023)

Stilbenes with potent cytotoxicity from the seedcases of Paeonia suffruticosa Andrews - Meng-Yue Yang; Zhao-Xiang Shao; Yue-Tong Wang; Yong-Lian Hou; Ding-Kang Zhu; Sha Chen; Ya-Hui Zhang; Fei Cao; Yong-Kui Jing; Bin Lin; Zhan-Lin Li; Da-Hong Li; et al. (Phytochemistry, 2023)

Biogenetic peloidal micrites within coral skeletons cause geochemical anomalies in reef limestones, Zhongsha Atoll, South China Sea - Hong-Qiang Yang; Xi-Yang Zhang; Yue Li; Qi Shi; Shi-Chen Tao; Xi-Nan Mu; Ming-Zhuang Wang; Xiao-Ju Liu; Fei Tan; Sheng-Nan Zhou; Guan Wang (Palaeogeography, Palaeoclimatology, Palaeoecology, 2023)

Phylogeny, character evolution, and biogeography of the fern genus Bolbitis (Dryopteridaceae) - Li-Yun Nie; Liang Zhang; Zhen-Long Liang; Rossarin Pollawatn; Yue-Hong Yan; Ngan Thi Lu; Ralf Knapp; Xia Wan; Daniele Cicuzza; Xin-Xin Cheng; Hong-Feng Chen; Ai-Hua Wang; et al. (Molecular Phylogenetics and Evolution, 2023)

Can evaporation from urban impervious surfaces be ignored? - Han Chen; Jinhui Jeanne Huang; Hong Liang; Weimin Wang; Han Li; Yizhao Wei; Albert Z. Jiang; Pengwei Zhang (Journal of Hydrology, 2023)

Microbial plankton responses to perfluoroalkyl acids and their alternatives in the aquatic environment - Shuo Wang; Tong Liu; Xin Qian; Hui Wang; Mingjia Li; Xuebing Wang; Si Wei; Hong Chen (Journal of Hazardous Materials, 2023)

Insights into the influence on 2,4,6-trichlorophenol microbial reductive dechlorination process by exposure to microplastics - Jia-Qi Yang; Zhi-Ling Li; Bin Wu; Ya-Ru Jin; Di Cao; Jun Nan; Xue-Qi Chen; Wen-Zong Liu; Shu-Hong Gao; Ai-Jie Wang (Journal of Hazardous Materials, 2023)

A cascade lithium bromide absorption refrigeration/dehumidification system for efficient energy recovery: Development, 3E optimization and life cycle assessment - Aixiang Xu; Lanxiang Yang; Tingting Song; Mengjin Xu; Hong Chen; Li Xiang; Zhiqiang Liu; Sheng Yang (Journal of Cleaner Production, 2023)

Effect of gradual increase of atmospheric CO2 concentration on nitrification potential and communities of ammonia oxidizers in paddy fields - Bing-jie Ren; Li-dong Shen; Xin Liu; Jing-hao Jin; He-chen Huang; Mao-hui Tian; Yu-ling Yang; Wang-ting Yang; Jia-qi Liu; Cai-yu Geng; Hong-sheng Wu; Zheng-hua Hu (Journal of Environmental Management, 2023)

Study on the prepared bio-oil by catalytic hydrothermal liquefaction of antibiotic residues in ethanol-water reaction system with transition metal modified HZSM-5 - Jian Yang; Rui Ma; Yi Xing; Hongzhi Ma; Biqin Dong; Hongxia Li; Chen Hong; Changlei Xia (Fuel, 2023)

Anaerobic membrane bioreactor for carbon-neutral treatment of industrial wastewater containing N, N-dimethylformamide: Evaluation of electricity, bio-energy production and carbon emission - Zhe Kong; Tianwei Hao; Hong Chen; Yi Xue; Dapeng Li; Yang Pan; Yong Li; Yu-You Li; Yong Huang (Environmental Research, 2023)

Accumulated temperature and allocation of photo-thermal resources are key meteorological factors affecting rice cadmium content - Wei Zhou; Fengjun Yan; Yu Fan; Chi Zhang; Fan Yang; Qi Liu; Tao Wang; Bo Li; Yong Chen; Fei Deng; Jianfeng Hu; Xiaolong Lei; et al. (European Journal of Agronomy, 2023)

Solid-liquid interface adsorption of antibiotic resistance plasmids induced by nanoplastics aggravates gene pollution in aquatic ecosystems - Zhiheng Li; Mengjun Wang; Hong Fang; Zhangchao Yao; Huijun Liu; Wenlu Zhao; Jie Chen (Environmental Pollution, 2023)

Evolving a high-performance bio-imaging tool derived from a compact fluorophore as well as creating a reaction-based fluorescent probe for precise determination of Ag+ - Zi Yi Xu; Xiao Hu Wang; Sha Li Huang; Jing Rong Chen; Hong Qun Luo; Nian Bing Li (Chemical Engineering Journal, 2023)

Graphene induced structure and doping level tuning of evaporated CsPbBr3 on different substrates - Zhaorui Wen; Yunlei Zhong; Bingchen He; Gang Wang; Shengwen Li; Zhen Mu; Jielei Li; Junpeng Xie; Yi Zheng; Guichuan Xing; Guo Hong; Shi Chen (Chemical Engineering Journal, 2023)

Formation mechanism and metabolic pathways of photogranule in batch and continuous-flow mode under high salinity stress - Jing Zhu; Hong You; Zhipeng Li; Binghan Xie; Weirun Li; Shaojie Qi; Rui Wang; Hongying Chen; Binyu Ma; Yi Ding; Haili Tan; Feng Liu; et al. (Chemical Engineering Journal, 2023)

Unravelling Effective-Medium transport and interfacial resistance in (CaTe) (GeTe)100- thermoelectrics - Meng Li; Sheng-Duo Xu; Wan-Yu Lyu; Qiang Sun; Min Hong; Yuan Wang; Ji-Xing Liu; Yu Yin; Jin Zou; Zhi-Gang Chen (Chemical Engineering Journal, 2023)

High performance of Mn-doped VO2 cathode for aqueous zinc-ion batteries: An insight into Zn2+ storage mechanism - Shiyao Deng; Hong Li; Bohong Chen; Zijie Xu; Yu Jiang; Chuanhua Li; Wei Xiao; Xuemin Yan (Chemical Engineering Journal, 2023)

Lanthanoid hydrogen-bonded organic frameworks: Enhancement of luminescence by the coordination-promoted antenna effect and applications in heavy-metal ion sensing and sterilization - Yun-Lan Li; Hai-Ling Wang; Zhi-Chuan Chen; Zhong-Hong Zhu; Yan-Cheng Liu; Rui-Yun Yang; Fu-Pei Liang; Hua-Hong Zou (Chemical Engineering Journal, 2023)

Spraying EPDM@NPs as an efficient strategy for polyethylene-based high-voltage insulation - Fan-Bo Meng; Xiangrong Chen; Yiwen Shi; Zelin Hong; Hanshan Zhu; Awais Muhammad; Hao Li; Ashish Paramane (Chemical Engineering Journal, 2023)

Ir nanodots decorated Ni3Fe nanoparticles for boosting electrocatalytic water splitting - Yaru Li; Yong-Chen Miao; Chen Yang; Yu-Xin Chang; Yu Su; Hong Yan; Sailong Xu (Chemical Engineering Journal, 2023)

Age differences in thermal comfort and physiological responses in thermal environments with temperature ramp - Yuxin Wu; Zixuan Zhang; Hong Liu; Baizhan Li; Baofan Chen; Risto Kosonen; Juha Jokisalo (Building and Environment, 2023)

Resistance of QYm.nau-2D to wheat yellow mosaic virus was derived from an alien introgression into common wheat - Yiming Chen; Jialun Ji; Dehui Kong; Xiong Tang; Mingxing Wen; Guoqing Wang; Keli Dai; Peiyao Shi; Xu Zhang; Huajian Zhang; Chengzhi Jiao; Zongkuan Wang; et al. (Theoretical and Applied Genetics, 2023)

The Nucleus Accumbens CRH–CRHR1 System Mediates Early-Life Stress-Induced Sleep Disturbance and Dendritic Atrophy in the Adult Mouse - Ting Wang; Yu-Nu Ma; Chen-Chen Zhang; Xiao Liu; Ya-Xin Sun; Hong-Li Wang; Han Wang; Yu-Heng Zhong; Yun-Ai Su; Ji-Tao Li; Tian-Mei Si (Neuroscience Bulletin, 2023)

Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease - Li-Sha Ran; Ya-Zeng Wu; Yi-Wen Gan; Hong-Lian Wang; Li-Juan Wu; Chun-Mei Zheng; Yao Ming; Ran Xiong; Yong-Lin Li; Shi-Hang Lei; Xue Wang; Xiao-Qing Lao; et al. (Journal of Natural Medicines, 2023)
Excessive intrahepatocellular lipid accumulation or steatosis is caused by abnormal lipid metabolism and a common character of nonalcoholic fatty liver disease (NAFLD), which may progress into cirrhosis and hepatocellular cancer. Andrographolide (Andro) is the primary active ingredient extracted from Andrographis paniculata , showing a protective role against dietary steatosis with the mechanism not fully understood. In this study, we showed that administration of Andro (50, 100, and 200 mg/kg/day for 8 weeks, respectively) attenuated obesity and metabolic syndrome in high-fat diet (HFD)-fed mice with improved glucose tolerance, insulin sensitivity, and reduced hyperinsulinemia, hyperglycemia, and hyperlipidemia. HFD-fed mice presented hepatic steatosis, which was significantly prevented by Andro. In vitro, Andro decreased the intracellular lipid droplets in oleic acid-treated LO2 cells. The selected RT-PCR array revealed a robust expression suppression of the fatty acid transport proteins (FATPs) by Andro treatment. Most importantly, we found that Andro consistently reduced the expression of FATP2 in both the oleic acid-treated LO2 cells and liver tissues of HFD-fed mice. Overexpression of FATP2 abolished the lipid-lowering effect of Andro in oleic acid-treated LO2 cells. Andro treatment also reduced the fatty acid uptake in oleic acid-treated LO2 cells, which was blunted by FATP2 overexpression. Collectively, our findings reveal a novel mechanism underlying the anti-steatosis effect of Andro by suppressing FATP2-mediated fatty acid uptake, suggesting the potential therapeutic application of Andro in the treatment of NAFLD. Graphical abstract

Geographical, Sex, Age, and Seasonal Differences in Serum Manganese Status Among Chinese Adults with Hypertension - Hong Chen; Zhixin Cui; Wenhai Lu; Ping Wang; Jia Wang; Ziyi Zhou; Nan Zhang; Zhuo Wang; Tengfei Lin; Yun Song; Lishun Liu; Xiao Huang; et al. (Biological Trace Element Research, 2023)

GNSS antispoofing method using the intersection angle between two directions of arrival (IA-DOA) for multiantenna receivers - Zhiyuan Chen; Hong Li; Yimin Wei; Ziheng Zhou; Mingquan Lu (GPS Solutions, 2023)

The dual detection of formaldehydes and sulfenic acids with a reactivity fluorescent probe in cells and in plants - Man Li; Zhiyi Cai; Mengzhao Li; Linfeng Chen; Weili Zeng; Hong Yuan; Chunrong Liu (Analytica Chimica Acta, 2023)

Solar ring mission: Building a panorama of the Sun and inner-heliosphere - Yuming Wang; Xianyong Bai; Changyong Chen; Linjie Chen; Xin Cheng; Lei Deng; Linhua Deng; Yuanyong Deng; Li Feng; Tingyu Gou; Jingnan Guo; Yang Guo; et al. (Advances in Space Research, 2023)

Decreases in the urban heat island effect during the Coronavirus Disease 2019 ( COVID ‐19) lockdown in Wuhan, China: Observational evidence - Sun Shanlei; Zhou Decheng; Chen Haishan; Li Jinjian; Ren Yongjian; Liao Hong; Liu Yibo (International Journal of Climatology, 2022)
The Coronavirus Disease 2019 (COVID‐19) lockdown in early 2020 reduced human activities in Wuhan, China, thereby altering the urban heat island (UHI) effect. The epidemic period (EP) during January 1, 2020–May 31, 2020 is divided into four stages, including pre‐lockdown, first (EP_LS1) and second (EP_LS2) lockdown, and after‐lockdown (EP_ALS) stages, which are identified according to different antivirus measures in early 2020 and confirmed by comparing the daily electricity consumption over the Wuhan metropolitan area during 2020 and 2019. Then, the Wuhan UHI intensity (UHII) during each stage is compared to that during the baseline period of 2016–2019 and 2021. Daytime, night‐time, and daily UHIIs are reduced; the larger decrease is during EP_LS1 and EP_LS2, of which EP_LS1 with the strictest antivirus measures shows a significant decrease (

Selenium attenuates the association of co-exposure to arsenic, cadmium, and lead with cognitive function among Chinese community-dwelling older adults - Bei-Jing Cheng; Jie Sheng; Hong-Li Wang; Yuan Wang; Hong-Juan Cao; Xiu-De Li; Ting-Ting Zhou; Xiang-Long Meng; Huan-Huan Nie; Su-Fang Wang; Dong-Mei Zhang; Gui-Mei Chen; et al. (Environmental Science and Pollution Research, 2022)

Study on typhoon disaster assessment by mining data from social media based on artificial neural network - Shaopan Li; Yan Wang; Hong Huang; Lida Huang; Yang Chen (Natural Hazards, 2022)

The AP2/ERF transcription factor SlERF.J2 functions in hypocotyl elongation and plant height in tomato - Yanan Chen; Hong Yang; Boyan Tang; Fenfen Li; Qiaoli Xie; Guoping Chen; Zongli Hu (Plant Cell Reports, 2022)

Magnetic Plug Sensor with Bridge Nonlinear Correction Circuit for Oil Condition Monitoring of Marine Machinery - Yuwei Zhang; Jiaju Hong; Haotian Shi; Yucai Xie; Hongpeng Zhang; Shuyao Zhang; Wei Li; Haiquan Chen (Journal of Marine Science and Engineering, 2022)
Diesel engines in marine power systems often work in extreme environments. Oil monitoring technology can guarantee the operational safety of diesel engines. In this paper, a magnetic plug sensor for oil debris monitoring is proposed to improve sensitivity and accuracy. Through finite element analysis, absolute deviation is reduced by optimizing the sensor structure. A bridge nonlinear correction circuit is designed to make sensitivity consistent over the entire scale range, which can facilitate calibration and data processing. In order to reduce noise and amplify the signal effectively, a signal post-processing circuit is adopted as well, which consists of a first stage filter circuit, a second stage filter, an active filter module, and an instrumentation amplifier. Therefore, this magnetic plug sensor exhibits better sensitivity and accuracy. Furthermore, a void test and a dynamic test are carried out to investigate its performance. There is a linear relationship between the voltage and the particle mass for the sensor with a bridge nonlinear correction circuit. The results illustrate a minimum of 0.033 mg iron debris with a 1.647 signal-to-noise ratio. Additionally, it can capture and detect 47 μm particles with a debris capture rate of over 90%, which allows it to excel in early fault diagnosis as well.

Body mass index–based predictions and personalized clinical strategies for colorectal cancer in the context of PPPM - Yun-Jia Gu; Li-Ming Chen; Mu-En Gu; Hong-Xiao Xu; Jing Li; Lu-Yi Wu (EPMA Journal, 2022)
Currently colorectal cancer (CRC) is the third most prevalent cancer worldwide. Body mass index (BMI) is frequently used in CRC screening and risk assessment to quantitatively evaluate weight. However, the impact of BMI on clinical strategies for CRC has received little attention. Within the framework of the predictive, preventive, and personalized medicine (3PM/PPPM), we hypothesized that BMI stratification would affect the primary, secondary, and tertiary care options for CRC and we conducted a critical evidence-based review. BMI dynamically influences CRC outcomes, which helps avoiding adverse treatment effects. The outcome of surgical and radiation treatment is adversely affected by overweight (BMI ≥ 30) or underweight (BMI < 20). A number of interventions, such as enhanced recovery after surgery and robotic surgery, can be applied to CRC at all levels of BMI. BMI-controlling modalities such as exercise, diet control, nutritional therapy, and medications may be potentially beneficial for patients with CRC. Patients with overweight are advised to lose weight through diet, medication, and physical activity while patients suffering of underweight require more focus on nutrition. BMI assists patients with CRC in better managing their weight, which decreases the incidence of adverse prognostic events during treatment. BMI is accessible, noninvasive, and highly predictive of clinical outcomes in CRC. The cost–benefit of the PPPM paradigm in developing countries can be advanced, and the clinical benefit for patients can be improved with the promotion of BMI-based clinical strategy models for CRC.

MdbHLH51 plays a positive role in anthocyanin accumulation in ‘Red Delicious’ apples - Gai-Xing Ning; Wen-Fang Li; Ming-Yu Chu; Zong-Huan Ma; Ping Wang; Juan Mao; Bai-Hong Chen (Trees, 2022)

Promoting Oligodendrocyte Differentiation from Human Induced Pluripotent Stem Cells by Activating Endocannabinoid Signaling for Treating Spinal Cord Injury - Hong Gao; Ying Guo; Sangita Biswas; Jing Li; Haojie Zhang; Zhaolin Chen; Wenbin Deng (Stem Cell Reviews and Reports, 2022)

Effect of Liquid Nitrogen Freezing on the Mechanical Strength and Fracture Morphology in a Deep Shale Gas Reservoir - Hai Qu; Chengying Li; Chengwei Qi; Xiangjun Chen; Yang Xu; Hong Jun; Xiaoguang Wu (Rock Mechanics and Rock Engineering, 2022)

Evidence in Support of Analogical Reasoning Improvements with Executive Attention Intervention in Healthy Young Adults - Yixuan Lin; Qing Li; Mengke Zhang; Yujie Su; Xiangpeng Wang; Hong Li; Antao Chen (Neuroscience Bulletin, 2022)

Effect and Mechanism of Cotrimoxazole Against Talaromyces marneffei in vitro - Jie Chen; Rongfeng Chen; Wudi Wei; Fengxiang Qin; Xiu Chen; Jinhao He; Hong Zhang; Gang Wang; Minjuan Shi; Tongxue Qin; Yinlu Liao; Yuting Wu; et al. (Mycopathologia, 2022)

Transplantation of Nasal Olfactory Mucosa Mesenchymal Stem Cells Benefits Alzheimer’s Disease - Chun-Gu Hong; Meng-Lu Chen; Ran Duan; Xin Wang; Zhi-Lin Pang; Li-Te Ge; Ming Lu; Hui Xie; Zheng-Zhao Liu (Molecular Neurobiology, 2022)

Microplastic pollution and its impact on marine microbes in Zhanjiang, China - Qing-Lang Song; Fang-Hong Nie; Di-Hua Zhu; Yun-Li Wei; Min Zhang; Yao Hu; Meng-Meng Chen; Dan-Ju Kang; Zhi-Bao Chen; Hong-Ying Lin; Jin-Jun Chen (Journal of Coastal Conservation, 2022)

RCAN1 deficiency aggravates sepsis-induced cardiac remodeling and dysfunction by accelerating mitochondrial pathological fission - Jinqiang Zhuang; Liming Chen; Gongke Li; Le Xia; Shaohong Wu; Junling Leng; Xuefei Tao; Jiang Hong; Yong Wu; Shijun Wang; Ruijun Yuan (Inflammation Research, 2022)

The association between essential trace element mixture and atherosclerotic cardiovascular disease risk among Chinese community-dwelling older adults - Xiang-long Meng; Yuan Wang; Hong-li Wang; Huan-huan Nie; Bei-jing Cheng; Hong-juan Cao; Xiu-de Li; Su-fang Wang; Gui-mei Chen; Fang-biao Tao; Jie Sheng; Lin-sheng Yang (Environmental Science and Pollution Research, 2022)

Gender-specific effects of prenatal mixed exposure to serum phthalates on neurodevelopment of children aged 2–3 years:the Guangxi Birth Cohort Study - Yuan Zheng; Longman Li; Hong Cheng; Shengzhu Huang; Xiuming Feng; Lulu Huang; Luyun Wei; Dehao Cao; Sida Wang; Long Tian; Weijun Tang; Caitong He; et al. (Environmental Science and Pollution Research, 2022)

Land subsidence calculation model under the coupling effect of groundwater and coal mining - Yiguo Xue; Hong Chen; Fanmeng Kong; Zhiqiang Li; Daohong Qiu; Qiqi Chen; Fan Yang; Xudong Jiang (Earth Science Informatics, 2022)

Effect of Iron Plaque on Gaseous Elemental Mercury Uptake, Translocation, and Volatilization by Paddy Rice - Yanlin Wang; Shuai Shang; Xin Li; Sinan Chen; Ran Li; Weiwei Jia; Hong Deng (Bulletin of Environmental Contamination and Toxicology, 2022)

Classification of primary dysmenorrhea by brain effective connectivity of the amygdala: a machine learning study - Siyi Yu; Liying Liu; Ling Chen; Menghua Su; Zhifu Shen; Lu Yang; Aijia Li; Wei Wei; Xiaoli Guo; Xiaojuan Hong; Jie Yang (Brain Imaging and Behavior, 2022)

Microplastics in Surface Waters and Floodplain Sediments of the Dagu River in the Jiaodong Peninsula, China - Jie Jiao; Gang Chen; Zechuan Yang; Zhengyan Li; Hong Hu (Journal of Ocean University of China, 2022)

The Seasonal and Stage-Specific Expression Patterns of HMGB2 Suggest Its Key Role in Spermatogenesis in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis) - Wei Li; Junxian Zhu; Luo Lei; Chen Chen; Xiaoli Liu; Yakun Wang; Xiaoyou Hong; Lingyun Yu; Hongyan Xu; Xinping Zhu (Biochemical Genetics, 2022)

Transcriptome analysis of gonads and brain of giant freshwater prawn (Macrobrachium rosenbergii): screening and validation of genes related to germ cell development - Jie Wei; Kunhao Hong; Qiaoyan Zhou; Yakun Wang; Wei Li; Xiaoli Liu; Xiaoyou Hong; Chen Chen; Lingyun Yu; Xinping Zhu (Frontiers in Marine Science, 2022)
Macrobrachium rosenbergii is an important cultured shrimp worldwide, and its precocious puberty has led to serious economic losses. Although reproductive sterilization can avoid this problem, little is known about the molecular mechanisms underlying gonadal development and gametogenesis in M. rosenbergii . Here, we conducted transcriptome analysis of the ovaries, testes, and male/female brain tissues of M. rosenbergii to discover germ cell development-related genes. A total of 60,607 unigenes were identified, of which 20,963 unigenes could be functionally annotated. Eighteen candidate genes were identified by Venn diagram analysis, keyword, and known marker search, followed by elimination of low-expression and repetitive genes. Subsequent real-time quantitative reverse transcription polymerase chain reaction and in situ hybridization identified five genes ( RAD51 , vasa , SPDS , MRR , and Fem-1C ) associated with germ cell development— RAD51 , vasa , and SPDS were expressed in both male and female gonads, whereas Fem-1C was specifically expressed in the ovary and MRR in the testis. In the ovary, vasa , SPDS , and Fem-1C were mainly expressed in stage 1–3 oocytes, while RAD51 was expressed in stage 2–3 oocytes. In testis, vasa were significantly expressed in spermatogonia and primary spermatocytes, whereas RAD51 and SPDS were only enriched in spermatogonia and MRR in vas deferens. Our research indicates that these five genes are important germ cell development-related genes, of which RAD51 , SPDS , and Fem-1C were proven to function in germ cells of this species for the first time. The discovery of these genes could help develop molecular breeding techniques to overcome precocious puberty in M. rosenbergii .

Brevilaterin B from Brevibacillus laterosporus has selective antitumor activity and induces apoptosis in epidermal cancer - Zhou Chen; Lulu Wang; Yangliu Liu; Panpan Han; Dan Hong; Siting Li; Aijin Ma; Yingmin Jia (World Journal of Microbiology and Biotechnology, 2022)

Inverse problem of magneto-acoustic concentration tomography for magnetic nanoparticles with magnetic induction in a saturation magnetization state based on the least squares QR factorization method–trapezoidal method - Xiaoheng Yan; Hong Xu; Jun Li; Weihua Chen; Yu Hu (Medical & Biological Engineering & Computing, 2022)

Effect of simulated earthquake loading on radon exhalation from uranium tailings dam - Yan Chen; Changshou Hong; Xiangyang Li; Yong Liu; Yifan Chen; Xingwang Dai; Hong Wang; Dongying Lin (Environmental Science and Pollution Research, 2022)

Dongia deserti sp. nov., Isolated from the Gurbantunggut Desert Soil - Chun-Yan Lu; Lei Dong; Dong Wang; Shuai Li; Bao-Zhu Fang; Ming-Xian Han; Feng Liu; Hong-Chen Jiang; Iftikhar Ahmed; Wen-Jun Li (Current Microbiology, 2022)

Effect of gravel content on the detachment of colluvial deposits in Benggang - Li-ting Zhang; Fang Shuai; Li-bo Chen; Yan-he Huang; Jin-shi Lin; Yue Zhang; Hong-li Ge; Fang-shi Jiang (Journal of Mountain Science, 2022)

A histological study of vascular wall resident stem cells in venous malformations - Hou-Fu Xia; Wen-Qiang Lai; Gao-Hong Chen; Ye Li; Qi-Hui Xie; Yu-Lin Jia; Gang Chen; Yi-Fang Zhao (Cell and Tissue Research, 2022)

Effects of Different Oxytocin and Temperature on Reproductive Activity in Nile tilapia (Oreochromis niloticus): Based on Sex Steroid Hormone and GtHR Gene Expression - Jie Yu; Dayu Li; Jinglin Zhu; Zhiying Zou; Wei Xiao; Binglin Chen; Hong Yang (Fishes, 2022)
Luteinizing hormone receptor (LHR) and follicle-stimulating hormone receptor (FSHR) belong to the gonadotropic hormone receptors (GtHR), which are highly expressed in fish gonads and participate in the regulation of fish reproductive activities. Fish gonadal development and gamete maturation are not only regulated by their BPG axis but also affected by natural environmental factors (such as temperature, salinity, pH, nutrients, light, etc.). Nile tilapia (Oreochromis niloticus) is a farmed fish with a short reproductive cycle, fast growth, and high economic value. To study the relationship between gonadotropic hormone receptors (GtHR) and the reproductive activity of Nile tilapia, different oxytocin injection experiments and different temperature treatment experiments were set up, and the expression changes of the GtHR gene in the gonads and the concentration changes of the estradiol (E2) in the female serum and testosterone (T) in the male serum were determined employing a quantitative RT-PCR assay and enzyme-linked immunosorbent assay (ELISA), respectively. After the injection of oxytocin, with the change of E2 in females and T in males, the FSHR showed an expression pattern of first increase, then decrease, and the LHR showed an expression pattern of first increase, then decrease, and finally increase in the gonads, and the expression level of FSHR and LHR in the injection group was significantly higher than that in the control group at multiple time points; in addition, the expression level of FSHR and LHR in the oxytocin-combination injection group was higher than that in the single injection group. During 28 days of treatment at different temperatures, the sex steroid hormones and GtHR genes also showed regular changes, and the relationship between each group was 28 °C > 32 °C > 24 °C at most time points. According to the research results, it is speculated that FSHR and LHR play an important role in the development of Nile tilapia gonads and participate in the reproductive activities of Nile tilapia. By comparing and analyzing the changes in the sex steroid hormones and GtHR genes in each experimental group, it is speculated that different oxytocin injections could affect the expression of FSHR and LHR genes in Nile tilapia, and the combined effect of oxytocin was better than single oxytocin; the optimum temperature for the reproduction of Nile tilapia is between 28–32 °C. This study provides a theoretical basis for further elucidating the physiological functions and molecular mechanisms of FSHR and LHR and also provides a reference for the research of reproductive regulation in Nile tilapia.

Effects of climate change on the geographical distribution and potential distribution areas of 35 Millettia Species in China - Kai Zhao; Xuetong Li; Jingru Yang; Zebin Huang; Chunlian Li; Lewen Yao; Zekai Tan; Xianyi Wu; Shiyuan Huang; Yanghe Yuan; Zhengyi Hong; Qiuyang Cai; et al. (Environmental Science and Pollution Research, 2022)

Within-day variation and health risk assessment of trihalomethanes (THMs) in a chlorinated indoor swimming pool in China - Xianyun Zheng; Jingchao Xu; Ye Gao; Wanghong Li; Yimei Chen; Hong Geng; Jianwei Yue; Min Xu (Environmental Science and Pollution Research, 2022)

Identification of serum metabolites enhancing inflammatory responses in COVID-19 - Chen-Song Zhang; Bingchang Zhang; Mengqi Li; Xiaoyan Wei; Kai Gong; Zhiyong Li; Xiangyang Yao; Jianfeng Wu; Cixiong Zhang; Mingxia Zhu; Lei Zhang; Xiufeng Sun; et al. (Science China Life Sciences, 2022)

Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway - Dongbin Lyu; Fan Wang; Mengke Zhang; Weichieh Yang; Haijing Huang; Qinte Huang; Chenglin Wu; Nuoshi Qian; Meiti Wang; Huanfei Zhang; Sichai Zheng; Jing Chen; et al. (Psychopharmacology, 2022)

The strigolactone receptor SlDWARF14 plays a role in photosynthetic pigment accumulation and photosynthesis in tomato - Zhifei Li; Ying Pi; Changsheng Zhai; Dong Xu; Wenyao Ma; Hong Chen; Yi Li; Han Wu (Plant Cell Reports, 2022)

Dietary supplementation of two indigenous Bacillus spp on the intestinal morphology, intestinal immune barrier and intestinal microbial diversity of Rhynchocypris lagowskii - Xin-yu Lei; Dong-ming Zhang; Qiu-ju Wang; Gui-qin Wang; Yue-hong Li; Yu-rou Zhang; Men-nan Yu; Qi Yao; Yu-ke Chen; Zhi-xin Guo (Fish Physiology and Biochemistry, 2022)

Differences in small-world networks between methamphetamine and heroin use disorder patients and their relationship with psychiatric symptoms - Yan Liu; Qiang Li; Tianyi Zhang; Lei Wang; Yarong Wang; Jiajie Chen; Jia Zhu; Hong Shi; Wei Wang; Wei Li (Brain Imaging and Behavior, 2022)

Paracandidimonas lactea sp. nov., a urea-utilizing bacterium isolated from landfill - Chu Zhang; Qian Pu; Jun-jie Ying; Ying Chen; Cheng-ze Li; Hang-tao Wu; Bin-jie Wang; Yu-han Zhang; Guo-hong Zeng; Ou Li; Xiu-fang Hu; Cong Sun (Archives of Microbiology, 2022)

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline - Liangcai Zhao; Haowei Jiang; Jiaojiao Xie; Danjie Shen; Qingqing Yi; Jiapin Yan; Chen Li; Hong Zheng; Hongchang Gao (Molecular Neurobiology, 2022)

Examining asymmetric outer-core CAPE in sheared tropical cyclones based on the FNL data set - Yufan Dai; Qingqing Li; Lijuan Wang; Hong Chen (Frontiers of Earth Science, 2022)

Ovary transcriptomic analysis reveals regulation effects of dietary fish oil on hormone, lipid, and glucose metabolism in female adult spotted scat (Scatophagus argus) - Tuo Wang; Zhi-Long Liu; Guang-Li Li; Umar Farouk Mustapha; Charles Brighton Ndandala; Hong-Juan Shi; Chun-Hua Zhu; Hua-Pu Chen; Yang Huang; Dong-Neng Jiang (Frontiers in Marine Science, 2022)
In the aquaculture industry, fish oil is widely used as a nutritional supplement to promote the gonadal maturation of broodstocks, while the mechanism of fish oil on ovary development remain unclear. Herein, female adult spotted scat ( Scatophagus argus ) with most ovaries at phase II were fed with diets containing 8% soybean oil (SO) or 8% fish oil (FO) for 60 days. The final average fish body weight was similar between FO and SO groups. The average gonadosomatic index (GSI) of FO group was higher (non-significant) than that of SO group. Finally, the phase IV ovary of the FO and SO groups were 7 and 5 out of 10, respectively. The serum estradiol (E2) level of the FO group was significantly higher than that of the SO group. The proportions of n-3 long-chain polyunsaturated fatty acids (LC-PUFA, such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)) in the ovaries were much higher in the FO group than in the SO group. These results suggest that the maturity level of the FO group is relatively higher than that of the SO group. Transcriptome sequencing was used to detect the ovary gene expression. Comparatively, the ovary transcriptome analysis showed 68 up-regulated and 193 down-regulated genes in the FO group. The expression levels of Jund and Jun necessary for the ovary maturation were up-regulated in the FO group, while Pparγ and Cxcl12 , which could inhibit the ovary development, were down-regulated in the FO group. Cyp3a27 coding the enzyme for degrading the estrogen was significantly down-regulated in the FO group and coincided with the increase of its serum E2. Kif5b which could regulate the glucose metabolism was up-regulated in the FO group. Serum insulin level was also increased in the FO group. Additionally, Aldh3a2 and Plin2 related to lipid metabolism were significantly down-regulated in the FO group. Briefly, dietary fish oil can influence the expression of genes related to steroid hormone, glucose and lipid metabolism. This study will clarify the mechanism of dietary fish oil in promoting ovary development in teleost fish.

A κ-OR Agonist Protects the Endothelial Function Impaired by Hyperuricemia Through Regulating the Akt/eNOS Signal Pathway - Qin Zheng; Qi Wu; Hong Yang; Qiuhong Chen; Xiaohui Li; Jingyi Guo (Probiotics and Antimicrobial Proteins, 2022)

Causal Effect of Genetically Determined Blood Copper Concentrations on Multiple Diseases: A Mendelian Randomization and Phenome-Wide Association Study - Xiuming Feng; Wenjun Yang; Lulu Huang; Hong Cheng; Xiaoting Ge; Gaohui Zan; Yanli Tan; Lili Xiao; Chaoqun Liu; Xing Chen; Zengnan Mo; Longman Li; et al. (Phenomics, 2022)

Overexpression of TaLAX3-1B alters the stomatal aperture and improves the salt stress resistance of tobacco - Luhua Li; Dingli Hong; Chang An; Yuxuan Chen; Pengpeng Zhao; Xin Li; Fumin Xiong; Mingjian Ren; Ruhong Xu (Molecular Biology Reports, 2022)

Correction to: Exosome-Derived lncRNA NEAT1 Exacerbates Sepsis-Associated Encephalopathy by Promoting Ferroptosis Through Regulating miR-9-5p/ TFRC and GOT1 Axis - Xue-biao Wei; Wen-qiang Jiang; Ju-hao Zeng; Lin-qiang Huang; Hong-guang Ding; Yuan-wen Jing; Yong-li Han; Yi-chen Li; Sheng-long Chen (Molecular Neurobiology, 2022)

Updated taxonomy of Chinese Clavaria subg. Syncoryne (Clavariaceae, Agaricales): description of two new species and one newly recorded species - Jun Yan; Gui-Wu Li; Wen-Hao Liu; Zuo-Hong Chen; Ping Zhang (Mycological Progress, 2022)

Role of host plants in the suitability and dispersal of an omnivorous predator Arma chinensis Fallou (Hemiptera: Pentatomidae: Asopinae) in a biological control context - Ming-Zhen Pan; Zhi-Xiao Fu; Yu-Yan Li; Hong-Yin Chen; Li-Sheng Zhang; Tong-Xian Liu (Journal of Plant Diseases and Protection, 2022)

History of suicide attempts associated with the thinning right superior temporal gyrus among individuals with schizophrenia - Yi Yin; Jinghui Tong; Junchao Huang; Baopeng Tian; Song Chen; Shuping Tan; Zhiren Wang; Fude Yang; Yongsheng Tong; Fengmei Fan; Peter Kochunov; Neda Jahanshad; et al. (Brain Imaging and Behavior, 2022)

Association of cognitive impairment and reduced cortical thickness in prefrontal cortex and anterior cingulate cortex with treatment-resistant depression - Mu-Hong Chen; Wan-Chen Chang; Pei-Chi Tu; Wei-Chen Lin; Cheng-Ta Li; Wen-Sheng Huang; Ya-Mei Bai; Shih-Jen Tsai; Tung-Ping Su (Brain Imaging and Behavior, 2022)

Evansella halocellulosilytica sp. nov., an alkali-halotolerant and cellulose-dissolving bacterium isolated from bauxite residue - Guo-Hong Liu; Manik Prabhu Narsing Rao; Qian-Qian Chen; Jian-Mei Che; Huai Shi; Bo Liu; Wen-Jun Li (Extremophiles, 2022)

Size distribution, emission rate, and decay characteristics of particles emitted by printers - Changwei Zou; Miaoting Jiang; Hong Huang; Hunan Chen; Li Sheng; Jianlong Li; Chenglong Yu (Air Quality, Atmosphere & Health, 2022)

Pharmacokinetics of benapenem for injection in subjects with mild to moderate renal impairment - Haijing Yang; Min Zhang; Yuancheng Chen; Hong Ren; Hong Zhang; Chen Yu; Jianda Lu; Li You; Jicheng Yu; Hong Liang; Cuilan Xiao; Zishuang He; et al. (European Journal of Clinical Pharmacology, 2022)

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

Ancylobacter gelatini sp. nov., isolated from beach sediment of Zhairuo Island, China - Pinmei Wang; Huan Sheng; Kaiwen Zheng; Yi Hong; Sanjit Chandra Debnath; Cen Yan; Kejing Li; Gen Chen; Jinzhong Xu; Fabai Wu; Zhen Guo; Daoqiong Zheng (Archives of Microbiology, 2022)

Deep-Sea-Derived Fungi as Valuable Producers of Cytotoxic Secondary Metabolites and Their Leads Potential - Guangrong Zhao; Wenli Tang; Jianlong Zhang; Peimin Shi; Youzhi Li; Jiao Wang; Qingqin Shen; Haixia Si; Linlin Jiang; Xin Yu; Hongwei Zhu; Guozhong Chen; et al. (Frontiers in Marine Science, 2022)
Cancer is the leading lethal disease worldwide. Natural products have contributed significantly to the development of approved therapeutic agents. Therefore, research into new bioactive naturally sourced metabolites with lead potential is urgently needed. It is well-known that marine microorganisms are by far one of the most notable and prolific sources of bioactive natural products. Among them, deep-sea-derived fungi are extraordinarily adapted and metabolically active under extreme environmental conditions, which enable them to produce a large number of novel secondary metabolites. Chemical examination of deep-sea-derived fungi has yielded enormous amounts of cytotoxic natural products and potential drug leads. This review summarizes a total of 229 cytotoxic compounds isolated from deep-sea-derived fungi from 2010 to 2021. The emphasis is on the unique chemical diversity of these metabolic products, together with their relevant cytotoxic properties. Among the isolated metabolites, 82 compounds have been found to possess moderate to potent cytotoxic activities. Meanwhile, we also highlight some compounds with potent cytotoxicities (namely “star molecules”) considering their high drug lead potential. This review reveals deep-sea-derived fungi as considerable resources for the development of new drugs and the potential of the newly discovered secondary metabolites as valuable antitumor lead compounds.

Prediction of disability-free survival in healthy older people - Johannes Tobias Neumann; Le T. P. Thao; Anne M. Murray; Emily Callander; Prudence R. Carr; Mark R. Nelson; Rory Wolfe; Robyn L. Woods; Christopher M. Reid; Raj C. Shah; Anne B. Newman; Jeff D. Williamson; et al. (GeroScience, 2022)
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)

Testicular miRNAs and tsRNAs provide insight into gene regulation during overwintering and reproduction of Onychostoma macrolepis - Guofan Peng; Chao Zhu; Qingfang Sun; Jincan Li; Yining Chen; Yingjie Guo; Hong Ji; Fangxia Yang; Wuzi Dong (Fish Physiology and Biochemistry, 2022)

Dietary calcium pyruvate could improve growth performance and reduce excessive lipid deposition in juvenile golden pompano (Trachinotus ovatus) fed a high fat diet - Yiru Shao; Zhiyong Xie; Shusheng Liang; Cuiying Chen; Douglas R. Tocher; Li Lin; Yanhua Huang; Yuanyou Li; Dizhi Xie; Yucong Hong; Shuqi Wang; Cuihong You (Fish Physiology and Biochemistry, 2022)

The Association Between Arsenic Metabolism and Hypertension Among Population with Varying Arsenic Exposure Levels in China - Yinqiao Dong; Miao Zhou; Mingming Zhang; Huanhuan Wang; Yao Chen; Xudan Liu; Shuyi Yang; Hong Lang; Guifan Sun; Xin Li (Exposure and Health, 2022)

Knowledge domain and research progress in green consumption: a phase upgrade study - Han Huang; Ruyin Long; Hong Chen; Qianwen Li; Meifen Wu; Xin Gan (Environmental Science and Pollution Research, 2022)

Aberrant Gene Expression of Selenoproteins in Chicken Spleen Lymphocytes Induced by Mercuric Chloride - Jia-Hong Chu; Yu-Xue Yan; Xue-Wei Chen; Pei-Chao Gao; Lan-Xin Li; Rui-Feng Fan (Biological Trace Element Research, 2022)

Stability evaluation for steep bank slope with microseismic monitoring in Three Gorges Reservoir area - Qing-ming Xie; Kui Long; Zi-mu Li; Li-chuan Chen; Hong Liu; Hong Xu; Fei He; Dan Liang; Xue-kun Xiang; Qiang Ma (Journal of Mountain Science, 2022)

Study on Salicylanilide Analogue for Antioxidant Activity and Melanosis Prevention in Chinese White Shrimp ( Fenneropenaeus chinensis ) - Hua Fang; Mengyu Li; Hui Chen; Jun Chen; Zhuan Hong; Weizhu Chen; Meijuan Fang (Journal of Aquatic Food Product Technology, 2022)

Phenolic compounds from the sclerotia of Inonotus obliquus - Yan-Mei Wei; Li Yang; Wen-Li Mei; Hui-Qin Chen; Cai-Hong Cai; Wei Li; Wen-Hua Dong; Zhi-Bao Chen; Hao-Fu Dai (Natural Product Research, 2022)

Erratum to: MYH7B variants cause hypertrophic cardiomyopathy by activating the CaMK-signaling pathway - Peng Chen; Zongzhe Li; Jiali Nie; Hong Wang; Bo Yu; Zheng Wen; Yang Sun; Xiaolu Shi; Li Jin; Dao-Wen Wang (Science China Life Sciences, 2022)

PdeHCA2 affects biomass in Populus by regulating plant architecture, the transition from primary to secondary growth, and photosynthesis - Biligen-Gaowa Zhao; Guo Li; Yue-Feng Wang; Zhen Yan; Feng-Qin Dong; Ying-Chang Mei; Wei Zeng; Meng-Zhu Lu; Hong-Bin Li; Qing Chao; Bai-Chen Wang (Planta, 2022)

Predisposition to atrioventricular septal defects may be caused by SOX7 variants that impair interaction with GATA4 - Baolei Li; Zhuoyan Li; Jianping Yang; Nanchao Hong; Lihui Jin; Yuejuan Xu; Qihua Fu; Kun Sun; Yu Yu; Yanan Lu; Sun Chen (Molecular Genetics and Genomics, 2022)

Metagenomic analysis reveals wide distribution of phototrophic bacteria in hydrothermal vents on the ultraslow-spreading Southwest Indian Ridge - Hong Chen; Deng Hui Li; Ai Jun Jiang; Xue Gong Li; Shi Jun Wu; Jian Wei Chen; Meng Jie Qu; Xiao Qing Qi; Jie Dai; Rui Zhao; Wei-Jia Zhang; Shan Shan Liu; et al. (Marine Life Science & Technology, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

MiR-1260b protects against LPS-induced degenerative changes in nucleus pulposus cells through targeting TCF7L2 - Shijie Chen; Guixia Shi; Jin Zeng; Ping Huang Li; Yi Peng; Zhiyu Ding; Hong Qing Cao; Ruping Zheng; Weiguo Wang (Human Cell, 2022)

The Status of Polychlorinated Biphenyls (PCBs) Extract from Zhanjiang Mangrove Sediments and the Effects on Tissue Structure and Inflammatory Cytokines in Zebrafish Liver - Aftab Qamar; Javaria Waheed; Sahar Ghulam Mohyuddin; Zhi-Bao Chen; Dan-Ju Kang; Zhang Li; Glen Hay Anthony; Ravi Gooneratne; Fang-Hong Nie; Jin-Jun Chen (Bulletin of Environmental Contamination and Toxicology, 2022)

Neobacillus rhizophilus sp. nov. and Neobacillus citreus sp. nov., isolated from the citrus rhizosphere soil - Guo-Hong Liu; Manik Prabhu Narsing Rao; Qian-Qian Chen; Huai Shi; Jian-Mei Che; Bo Liu; Wen-Jun Li (Archives of Microbiology, 2022)

Geochronology and geochemistry of Late Triassic intrusions in the Liaodong Peninsula, eastern North China Craton: implications for post-collisional lithospheric thinning - Chen Wang; Zheng-Hong Liu; Gang Li; Xiao-Jie Dong; Shi-Chao Li; Qing-Ying Zhao (International Geology Review, 2022)

A new picrotoxane-type sesquiterpene from Dendrobium nobile Lindl - Pei Wang; Xin Chen; Cai-Hong Cai; Fan-Dong Kong; Sheng-Zhuo Huang; Jing-Zhe Yuan; Xing-Lian Xu; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2022)

Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities - Ying-Ying Chen; Jiang-Ping Hou; Ling Huang; Afsar Khan; Fei-Fei Xing; Xiao-Han Zhang; De-Feng Han; Shi-Li Yan; Gui-Dong Cao; Qi-Yang Jiao; Dejie Liu; Xuwei Zhu; et al. (Natural Product Research, 2022)

Soil phosphorus availability and stoichiometry determine microbial activity and functional diversity of fluvo-aquic soils under long-term fertilization regimes - Wei He; Wenhua Ye; Mingjie Sun; Yaping Li; Manman Chen; Meng Wei; Guoqing Hu; Quangang Yang; Hong Pan; Yanhong Lou; Hui Wang; Yuping Zhuge (Journal of Soils and Sediments, 2022)

Cavin-1 promotes M2 macrophages/microglia polarization via SOCS3 - Wei Huang; Yiyi Hong; Wenjing He; Li Jiang; Wen Deng; Biyan Peng; Fen Tang; Chaolan Shen; Qianqian Lan; Hui Huang; Haibin Zhong; Jian Lv; et al. (Inflammation Research, 2022)

Association between congenital heart defects and maternal manganese and iron concentrations: a case–control study in China - Meixian Wang; Yan Tian; Ping Yu; Nana Li; Ying Deng; Lu Li; Hong Kang; Dapeng Chen; Hui Wang; Zhen Liu; Juan Liang (Environmental Science and Pollution Research, 2022)
To investigate the correlation between maternal manganese and iron concentrations and the risk of CHD among their infant. A multi-center hospital-based case control study was conducted in China. There were 322 cases and 333 controls have been selected from pregnant women who received prenatal examinations. Correlations between CHDs and maternal manganese and iron concentrations were estimated by conditional logistic regression. Moreover, the interaction between manganese and iron on CHDs was analyzed. Compared with the controls, mothers whose hair manganese concentration was 3.01 μg/g or more were more likely to have a child with CHD than those with a lower concentration. The adjusted OR was 2.68 (95%CI = 1.44–4.99). The results suggested that mothers whose iron content was 52.95 μg/g or more had a significantly higher risk of having a child with CHD ( aOR = 2.87, 95%CI = 1.54–5.37). No interaction between maternal manganese and iron concentrations was observed in the multiplicative or additive model. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD ( OR = 7.02). Women with excessive manganese concentrations have a significantly increased risk of having offspring with CHDs. The high maternal iron status also correlates with CHDs. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD.

Molybdenum background and pollution levels in the Taipu River, China - Feipeng Li; Yue Wang; Lingchen Mao; Hong Tao; Mengmeng Chen (Environmental Chemistry Letters, 2022)

Correction to: Lederbergia citri sp. nov., and Lederbergia citrisecundus sp. nov., isolated from citrus rhizosphere - Guo‑Hong Liu; Manik Prabhu Narsing Rao; Qian‑Qian Chen; Jian‑Mei Che; Huai Shi; Bo Liu; Wen‑Jun Li (Current Microbiology, 2022)

Monitoring the behavior of subway tunnels during early operation in saturated soft strata - Ben-Guo He; Rong-Li Zhen; Tian-Yu Chen; Hong-Pu Li (Bulletin of Engineering Geology and the Environment, 2022)

Correction to: Spindle‑related brain activation in patients with insomnia disorder: An EEG‑fMRI study - Yan Shao; Guangyuan Zou; Serik Tabarak; Jie Chen; Xuejiao Gao; Ping Yao; Jiayi Liu; Yuezhen Li; Nana Xiong; Wen Pan; Mengying Ma; Shuqin Zhou; et al. (Brain Imaging and Behavior, 2022)

Spindle-related brain activation in patients with insomnia disorder: An EEG-fMRI study - Yan Shao; Guangyuan Zou; Serik Tabarak; Jie Chen; Xuejiao Gao; Ping Yao; Jiayi Liu; Yuezhen Li; Nana Xiong; Wen Pan; Mengying Ma; Shuqin Zhou; et al. (Brain Imaging and Behavior, 2022)

A review on food processing and preparation methods for altering fish allergenicity - Binaka Prabashini Dasanayaka; Zhenxing Li; Siddanakoppalu Narayana Pramod; Yan Chen; Mati Ullah Khan; Hong Lin (Critical Reviews in Food Science and Nutrition, 2022)

Extensive sequence divergence between the reference genomes of Taraxacum kok-saghyz and Taraxacum mongolicum - Tao Lin; Xia Xu; Huilong Du; Xiuli Fan; Qingwen Chen; Chunyan Hai; Zijian Zhou; Xiao Su; Liquan Kou; Qiang Gao; Lingwei Deng; Jinsheng Jiang; et al. (Science China Life Sciences, 2022)

Exosome-Derived lncRNA NEAT1 Exacerbates Sepsis-Associated Encephalopathy by Promoting Ferroptosis Through Regulating miR-9-5p/TFRC and GOT1 Axis - Xue-biao Wei; Wen-qiang Jiang; Ju-hao Zeng; Lin-qiang Huang; Hong-guang Ding; Yuan-wen Jing; Yong-li Han; Yi-chen Li; Sheng-long Chen (Molecular Neurobiology, 2022)
Sepsis can cause sepsis-associated encephalopathy (SAE), but whether SAE was induced or exacerbated by ferroptosis remains unknown. In this study, the rat sepsis model was constructed using the cecal ligation and puncture method. The blood–brain barrier (BBB) permeability was measured by Evans blue dye (EBD) in vivo. The levels of ROS, Fe ion, MDA, GSH, and GPX4 were assessed by enzyme-linked immunosorbent assay (ELISA). The exosomes isolated from serum were cultured with bEnd.3 cells for the in vitro analysis. Moreover, bEnd.3 cells cultured with 100 μM FeCl3 (iron-rich) were to simulate ferroptosis stress. The cell viability was evaluated by Cell Counting Kit-8 (CCK-8) assay. A dual-luciferase reporter gene assay was performed to confirm the relationship between miR-9-5p with NEAT1, TFRC , and GOT1 . In vivo, it is found that BBB permeability was damaged in model rats. Level of ROS, Fe ion, and MDA was increased, and level of GSH and GPX4 was decreased, which means ferroptosis was induced by sepsis. Exosome-packaged NEAT1 in serum was significantly upregulated in model rats. In vitro, it is found that NEAT1 functions as a ceRNA for miR-9-5p to facilitate TFRC and GOT1 expression. Overexpression of NEAT1 enhanced ferroptosis stress in bEnd.3 cells. Increased miR-9-5p alleviated sepsis-induced ferroptosis by suppressing the expression of TFRC and GOT1 both in vivo and in vitro. In conclusion, these findings suggest that sepsis induced high expression of serous exosome-derived NEAT1, and it might exacerbate SAE by promoting ferroptosis through regulating miR-9-5p/ TFRC and GOT1 axis.

Legacy organochlorines in estuarine sediment in relation to socioeconomic pattern in multi-coastal watersheds - Bing Hong; Min Zhou; Juan Li; Shen Yu; Bo Xu; Xun Liu; Peiji Chen; Tongtong Zhou; Yongshan Chen (Environmental Science and Pollution Research, 2022)

Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis - Zhuo-Zhi Liang; Yi-Xin Zhang; Rui-Mei Zhu; Yue-Lin Li; Hong-Mei Jiang; Ruo-Bi Li; Qian-Xin Chen; Qing Wang; Lu-Ying Tang; Ze-Fang Ren (Environmental Science and Pollution Research, 2022)

Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China - Tie-Ning Zhang; Qi-Jun Wu; Yan-Hong Huang; Jing Li; Zong-Jiao Chen; Li-Li Li; Yan-Ling Chen; Shu Liu; Cheng-Zhi Jiang; Yu-Hong Zhao (Environmental Science and Pollution Research, 2022)

Is Zooplankton Body Size an Indicator of Water Quality in (Sub)tropical Reservoirs in China? - Li Wang; Jun Chen; Haojie Su; Xufa Ma; Zhixu Wu; Hong Shen; Jia Yu; Jiarui Liu; Yao Wu; Guangyi Ding; Ping Xie (Ecosystems, 2022)

Effectiveness of Disinfectants Suitable for Inactivating SARS-CoV-2 at Cold-Chain Temperature - Xiaosong Wu; Yin Chen; Ling Wang; Xiling Guo; Lunbiao Cui; Yiming Shen; Fang Li; Hong Sun; Liubo Zhang; Jin Shen; Yan Xu (Food and Environmental Virology, 2022)

Schwann-like cell conditioned medium promotes angiogenesis and nerve regeneration - Jiahong Yu; Kai Ye; Jing Li; Yusheng Wei; Jiqin Zhou; Wei Ni; Lei Zhang; Tianyan Chen; Bin Tang; Hong Xu; Jiabo Hu (Cell and Tissue Banking, 2022)