Challenges and solutions to biodiversity conservation in arid lands - Yuanming Zhang; Akash Tariq; Alice C. Hughes; Deyuan Hong; Fuwen Wei; Hang Sun; Jordi Sardans; Josep Peñuelas; Gad Perry; Jianfang Qiao; Alishir Kurban; Xiaoxia Jia; et al. (Science of The Total Environment, 2023)

Joint role of land cover types and microbial processing on molecular composition of dissolved organic matter in inland lakes - Zhicheng Hong; Hua Ma; Ting Zhang; Qianru Wang; Yilin Chang; Yingyue Song; Zhe Li; Fuyi Cui (Science of The Total Environment, 2023)

Formation pathways, gas-solid partitioning, and reaction kinetics of PCDD/Fs associated with baghouse filters operated at high temperatures: A case study - Xiaoqing Lin; Xiaoxiao Wang; Yuxuan Ying; Angjian Wu; Zhiliang Chen; Lei Wang; Hong Yu; Hao Zhang; Aizhong Ruan; Xiaodong Li; Jianhua Yan (Science of The Total Environment, 2023)

Mapping Chinese annual gross primary productivity with eddy covariance measurements and machine learning - Xian-Jin Zhu; Gui-Rui Yu; Zhi Chen; Wei-Kang Zhang; Lang Han; Qiu-Feng Wang; Shi-Ping Chen; Shao-Min Liu; Hui-Min Wang; Jun-Hua Yan; Jun-Lei Tan; Fa-Wei Zhang; et al. (Science of The Total Environment, 2023)

Insights into production and consumption processes of nitrous oxide emitted from soilless culture systems by dual isotopocule plot and functional genes - Wei Lin; QiaoZhen Li; Wanlai Zhou; Rui Yang; Dongdong Zhang; Hong Wang; Yujia Li; Zhiyong Qi; Yuzhong Li (Science of The Total Environment, 2023)

Reducing food-system nitrogen input and emission through circular agriculture in montane and coastal regions - Li Xing; Tao Lin; Yuanchao Hu; Meixia Lin; Yuqin Liu; Guoqin Zhang; Hong Ye; Xiongzhi Xue (Resources, Conservation and Recycling, 2023)

Charge instability of topological Fermi arcs in chiral crystal CoSi - Zhicheng Rao; Quanxin Hu; Shangjie Tian; Qing Qu; Congrun Chen; Shunye Gao; Zhenyu Yuan; Cenyao Tang; Wenhui Fan; Jierui Huang; Yaobo Huang; Li Wang; et al. (Science Bulletin, 2023)

Paddy rice methane emissions across Monsoon Asia - Zutao Ouyang; Robert B. Jackson; Gavin McNicol; Etienne Fluet-Chouinard; Benjamin R.K. Runkle; Dario Papale; Sara H. Knox; Sarah Cooley; Kyle B. Delwiche; Sarah Feron; Jeremy Andrew Irvin; Avni Malhotra; et al. (Remote Sensing of Environment, 2023)

A repeated dose 28-day oral toxicity study of sodium dehydroacetate (DHA-S) in Wistar rats - Hong-ju Du; Guo-hui Tong; Jun-yu Ning; Shan Gao; Qing Yang; Ying Feng; Peng Zhang; Wei Zhang; Hai-ming Jing; Guo-jun Li (Regulatory Toxicology and Pharmacology, 2023)

Widely targeted metabolomics analysis reveals the effect of exogenous auxin on postharvest resistance to Botrytis cinerea in kiwifruit (Actinidia chinensis L.) - Zhe-Xin Li; Shuai Yang; Xu Wang; Qin-Hong Liao; Wen-Lin Zhang; Jing Liu; Guo-Hua Liu; Jian-Min Tang (Postharvest Biology and Technology, 2023)

Stilbenes with potent cytotoxicity from the seedcases of Paeonia suffruticosa Andrews - Meng-Yue Yang; Zhao-Xiang Shao; Yue-Tong Wang; Yong-Lian Hou; Ding-Kang Zhu; Sha Chen; Ya-Hui Zhang; Fei Cao; Yong-Kui Jing; Bin Lin; Zhan-Lin Li; Da-Hong Li; et al. (Phytochemistry, 2023)

Sesquiterpenoids and monoterpenoids from the water decoction of Valeriana officinalis L - Shi-Wei Li; Bian-Xia Xue; Tian-Tian Yang; Ran Li; Mingjie Zhang; Miao Wang; Li-Hua Zhang; Peng Zhang; Yi Zhang; Tao Wang; Shao-Xia Wang; Hong-Hua Wu (Phytochemistry, 2023)

Biogenetic peloidal micrites within coral skeletons cause geochemical anomalies in reef limestones, Zhongsha Atoll, South China Sea - Hong-Qiang Yang; Xi-Yang Zhang; Yue Li; Qi Shi; Shi-Chen Tao; Xi-Nan Mu; Ming-Zhuang Wang; Xiao-Ju Liu; Fei Tan; Sheng-Nan Zhou; Guan Wang (Palaeogeography, Palaeoclimatology, Palaeoecology, 2023)

Phylogeny, character evolution, and biogeography of the fern genus Bolbitis (Dryopteridaceae) - Li-Yun Nie; Liang Zhang; Zhen-Long Liang; Rossarin Pollawatn; Yue-Hong Yan; Ngan Thi Lu; Ralf Knapp; Xia Wan; Daniele Cicuzza; Xin-Xin Cheng; Hong-Feng Chen; Ai-Hua Wang; et al. (Molecular Phylogenetics and Evolution, 2023)

Ultra-depleted melt product preserved in the Ladong ophiolitic peridotites of the North Qilian Orogenic Belt, Northern Tibet - Xiang Zhou; Jian-Ping Zheng; Zeng-Bao Huang; Zhi-Yong Li; Wei-Qi Zhang; Hong-Da Zheng; Qing Xiong; Hong-Kun Dai (Lithos, 2023)

Can evaporation from urban impervious surfaces be ignored? - Han Chen; Jinhui Jeanne Huang; Hong Liang; Weimin Wang; Han Li; Yizhao Wei; Albert Z. Jiang; Pengwei Zhang (Journal of Hydrology, 2023)

Modeling study on the roles of the deposition and transport of PM2.5 in air quality changes over central-eastern China - Lei Zhang; Jianjun He; Sunling Gong; Xiaomei Guo; Tianliang Zhao; Huizheng Che; Hong Wang; Chunhong Zhou; Jingyue Mo; Ke Gui; Yu Zheng; Lei Li; et al. (Journal of Environmental Sciences, 2023)

Recovery of Ni matte from Ni-bearing electroplating sludge - Hong-Yang Wang; Yu Li; Shu-Qiang Jiao; Kuo-Chih Chou; Guo-Hua Zhang (Journal of Environmental Management, 2023)

Impact of hydrophilic functional groups of macromolecular organic fractions on food waste digestate dewaterability - Li Zhu; Hong Tao; Xiaohu Dai; Bin Dong; Wei Zhang (Journal of Environmental Management, 2023)

Efficient caproate production from ethanol and acetate in open culture system through reinforcement of chain elongation process - Cunsheng Zhang; Zhihui Ling; Li Yang; Yan Liu; Tianyu Cao; Yuxuan Sun; Weimin Liu; Shuhao Huo; Zhi-Hong Zhang; Haijia Su; Jan Baeyens; Xianghui Qi (Journal of Cleaner Production, 2023)

Formation mechanism of typical aromatic sulfuric anhydrides and their potential role in atmospheric nucleation process - Haijie Zhang; Rui Gao; Hong Li; Yunfeng Li; Yisheng Xu; Fahe Chai (Journal of Environmental Sciences, 2023)

Early Paleozoic collision-related structures in the Tarim Craton, NW China: Implications for the Proto-Tethys evolution - Yue-Jun Li; Yong-Jin Gao; Hui Zhou; Guang-Ya Zhang; Lei Wen; Yan Zhao; Cheng Li; Duo-Ming Zheng; Ya-Lei Liu; Hong-Hui Li; Cai-Ming Luo; Tong-Fei Huang; et al. (Journal of Asian Earth Sciences, 2023)

Differences in the effectiveness of the high-efficient concentrated pretreatment method on the norovirus detection in oysters and mussels - Yijing Li; Liang Xue; Junshan Gao; Weicheng Cai; Yanhui Liang; Zilei Zhang; Linping Wang; Xiaojing Hong; Luobing Meng; Mingfang Xu; Qingping Wu; Jumei Zhang (International Journal of Food Microbiology, 2023)

Impact of air pollutants on influenza-like illness outpatient visits under urbanization process in the sub-center of Beijing, China - Zhong-Song Zhang; Lu Xi; Li-Li Yang; Xin-Yao Lian; Juan Du; Yan Cui; Hong-Jun Li; Wan-Xue Zhang; Chao Wang; Bei Liu; Yan-Na Yang; Fuqiang Cui; et al. (International Journal of Hygiene and Environmental Health, 2023)

Construction of an unmarked genetically engineered strain Bacillus subtilis WB800-ipaH capable of degrading iprodione and its pilot application - Mingliang Zhang; Qian Li; Xuekun Bai; Siyuan Gao; Qian Zhu; Bin Ye; Yidong Zhou; Jiguo Qiu; Xin Yan; Qing Hong (International Biodeterioration & Biodegradation, 2023)

Molting-related proteases in the brown planthopper, Nilaparvata lugens - Yu-Cheng Xie; Hou-Hong Zhang; Han-Jing Li; Xiao-Ya Zhang; Xu-Mei Luo; Ming-Xing Jiang; Chuan-Xi Zhang (Insect Biochemistry and Molecular Biology, 2023)

Physicochemical properties, texture, and in vitro protein digestibility in high-moisture extrudate with different oil/water ratio - Hong Wang; Ruican Wang; Longteng Zhang; Wei Zhang; Serafim Bakalis; Yan Li; René Lametsch (Food Research International, 2023)

A chemometric study on the identification of 5-methylfurfural and 2-acetylfuran as particular volatile compounds of oxidized fish oil based on SHS-GC-IMS - Yun-Qi Wen; Hong-Wei Zhang; Chang-Hu Xue; Xiao-Han Wang; Shi-Jie Bi; Li-Li Xu; Qian-Qian Xue; Yong Xue; Zhao-Jie Li; Joaquín Velasco; Xiao-Ming Jiang (Food Chemistry, 2023)

Gut microbiota and metabolic profile as affected by Maillard reaction products derived from bighead carp meat hydrolysates with galactose and galacto-oligosaccharides during in vitro pig fecal fermentation - Yifan Liang; Huijuan Zhang; Li Tian; Ce Shi; Yanyan Zheng; Jinfeng Wang; Yuqing Tan; Yongkang Luo; Hui Hong (Food Chemistry, 2023)

Impact of wheat starch granule size on viscoelastic behaviors of noodle dough sheet and the underlying mechanism - Jiaying Shang; Bo Zhao; Chong Liu; Limin Li; Jing Hong; Mei Liu; Xiaohui Zhang; Yiming Lei; Xueling Zheng (Food Hydrocolloids, 2023)

PGC-1α/NRF1-dependent cardiac mitochondrial biogenesis: A druggable pathway of calycosin against triptolide cardiotoxicity - Xiao-Ming Qi; Yuan-Biao Qiao; Yuan-Lin Zhang; Ai-Cheng Wang; Jin-Hong Ren; Hui-Zhi Wei; Qing-Shan Li (Food and Chemical Toxicology, 2023)

A novel C1qDC (PoC1qDC) with a collagen domain in Paralichthys olivaceus mediates complement activation and against bacterial infection - Mo-fei Li; Hong-qiang Zhang; Jin-sheng Sun (Fish & Shellfish Immunology, 2023)

Accumulated temperature and allocation of photo-thermal resources are key meteorological factors affecting rice cadmium content - Wei Zhou; Fengjun Yan; Yu Fan; Chi Zhang; Fan Yang; Qi Liu; Tao Wang; Bo Li; Yong Chen; Fei Deng; Jianfeng Hu; Xiaolong Lei; et al. (European Journal of Agronomy, 2023)

Crystallization control of air-processed wide-bandgap perovskite for carbon-based perovskite solar cells with 17.69% efficiency - Lingcong Li; Ruike Zhang; Zhujie Wu; Yao Wang; Jin Hong; Huashang Rao; Zhenxiao Pan; Xinhua Zhong (Chemical Engineering Journal, 2023)

One-step fabrication of self-healing poly(thioctic acid) coatings on ZE21B Mg alloys for enhancing corrosion resistance, anti-bacterial/oxidation, hemocompatibility and promoting re-endothelialization - Zhao-Qi Zhang; Pei-Duo Tong; Li Wang; Zheng-Hui Qiu; Jing-An Li; Hang Li; Shao-Kang Guan; Cun-Guo Lin; Hong-Yan Wang (Chemical Engineering Journal, 2023)

Multi-functional bilayer carbon structures with micrometer-level physical encapsulation as a flexible cathode host for high-performance lithium-sulfur batteries - Yonghui Xie; Juan Ao; Li Zhang; Yeqing Shao; Hong Zhang; Shuying Cheng; Xinghui Wang (Chemical Engineering Journal, 2023)

High performance carbon dioxide electroreduction in ionic liquids with in situ shell-isolated nanoparticle-enhanced Raman spectroscopy - Ye Hu; Zhongdong Gan; Shixian Xin; Wenhui Fang; Min Li; Yanlei Wang; Wei Cui; Hong Zhao; Zengxi Li; Xiangping Zhang (Chemical Engineering Journal, 2023)

Passivation of positively charged cationic defects in perovskite with nitrogen-donor crown ether enabling efficient perovskite solar cells - Yuxuan Yang; Tao Zhao; Ming-Hua Li; Xiaoxue Wu; Mingyue Han; Shih-Chi Yang; Qiaoling Xu; Lede Xian; Xiang Chi; Ning-Jiu Zhao; Hong Cui; Sihan Li; et al. (Chemical Engineering Journal, 2023)

Age differences in thermal comfort and physiological responses in thermal environments with temperature ramp - Yuxin Wu; Zixuan Zhang; Hong Liu; Baizhan Li; Baofan Chen; Risto Kosonen; Juha Jokisalo (Building and Environment, 2023)

Building a satisfactory indoor environment for healthcare facility occupants: A literature review - Xiumei Shen; Hong Zhang; Ying Li; Kaichen Qu; Liang Zhao; Guangyan Kong; Wenzhao Jia (Building and Environment, 2023)

Low concentrations of benzophenone-type UV-filters impair testis development in the amphibian Xenopus laevis - Hong-Mei Li; Ying-Chi Zhang; Yuan-Yuan Li; Qing-Qing Zhu; Jie Li; Hai-Ming Xu; Yi-Ming Xiong; Zhan-Fen Qin (Aquatic Toxicology, 2023)

Resistance of QYm.nau-2D to wheat yellow mosaic virus was derived from an alien introgression into common wheat - Yiming Chen; Jialun Ji; Dehui Kong; Xiong Tang; Mingxing Wen; Guoqing Wang; Keli Dai; Peiyao Shi; Xu Zhang; Huajian Zhang; Chengzhi Jiao; Zongkuan Wang; et al. (Theoretical and Applied Genetics, 2023)

Combining Bone Collagen Matrix with hUC-MSCs for Application to Alveolar Process Cleft in a Rabbit Model - Xue-Cheng Sun; Hu Wang; Dan Zhang; Jian-Hui Li; Li-Qiang Yin; Yu-Fang Yan; Xu Ma; Hong-Fei Xia (Stem Cell Reviews and Reports, 2023)

The Nucleus Accumbens CRH–CRHR1 System Mediates Early-Life Stress-Induced Sleep Disturbance and Dendritic Atrophy in the Adult Mouse - Ting Wang; Yu-Nu Ma; Chen-Chen Zhang; Xiao Liu; Ya-Xin Sun; Hong-Li Wang; Han Wang; Yu-Heng Zhong; Yun-Ai Su; Ji-Tao Li; Tian-Mei Si (Neuroscience Bulletin, 2023)

Color medical image cryptography technology based on segmentation and fractional-order hyperchaotic system - Xie Hong-wei; Zhang Yu-zhou; Li Zhen-yu; Zhang Hao (Medical & Biological Engineering & Computing, 2023)

Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease - Li-Sha Ran; Ya-Zeng Wu; Yi-Wen Gan; Hong-Lian Wang; Li-Juan Wu; Chun-Mei Zheng; Yao Ming; Ran Xiong; Yong-Lin Li; Shi-Hang Lei; Xue Wang; Xiao-Qing Lao; et al. (Journal of Natural Medicines, 2023)
Excessive intrahepatocellular lipid accumulation or steatosis is caused by abnormal lipid metabolism and a common character of nonalcoholic fatty liver disease (NAFLD), which may progress into cirrhosis and hepatocellular cancer. Andrographolide (Andro) is the primary active ingredient extracted from Andrographis paniculata , showing a protective role against dietary steatosis with the mechanism not fully understood. In this study, we showed that administration of Andro (50, 100, and 200 mg/kg/day for 8 weeks, respectively) attenuated obesity and metabolic syndrome in high-fat diet (HFD)-fed mice with improved glucose tolerance, insulin sensitivity, and reduced hyperinsulinemia, hyperglycemia, and hyperlipidemia. HFD-fed mice presented hepatic steatosis, which was significantly prevented by Andro. In vitro, Andro decreased the intracellular lipid droplets in oleic acid-treated LO2 cells. The selected RT-PCR array revealed a robust expression suppression of the fatty acid transport proteins (FATPs) by Andro treatment. Most importantly, we found that Andro consistently reduced the expression of FATP2 in both the oleic acid-treated LO2 cells and liver tissues of HFD-fed mice. Overexpression of FATP2 abolished the lipid-lowering effect of Andro in oleic acid-treated LO2 cells. Andro treatment also reduced the fatty acid uptake in oleic acid-treated LO2 cells, which was blunted by FATP2 overexpression. Collectively, our findings reveal a novel mechanism underlying the anti-steatosis effect of Andro by suppressing FATP2-mediated fatty acid uptake, suggesting the potential therapeutic application of Andro in the treatment of NAFLD. Graphical abstract

Geographical, Sex, Age, and Seasonal Differences in Serum Manganese Status Among Chinese Adults with Hypertension - Hong Chen; Zhixin Cui; Wenhai Lu; Ping Wang; Jia Wang; Ziyi Zhou; Nan Zhang; Zhuo Wang; Tengfei Lin; Yun Song; Lishun Liu; Xiao Huang; et al. (Biological Trace Element Research, 2023)

Solar ring mission: Building a panorama of the Sun and inner-heliosphere - Yuming Wang; Xianyong Bai; Changyong Chen; Linjie Chen; Xin Cheng; Lei Deng; Linhua Deng; Yuanyong Deng; Li Feng; Tingyu Gou; Jingnan Guo; Yang Guo; et al. (Advances in Space Research, 2023)

SHAKING: Adjusted spherical harmonics adding KrigING method for near real-time ionospheric modeling with multi-GNSS observations - Ang Liu; Zishen Li; Ningbo Wang; Yan Zhang; Andrzej Krankowski; Hong Yuan (Advances in Space Research, 2023)

Association between short- and long-term exposures to air pollutants and internalizing/externalizing behavior in children aged 4 to 7 years - Haiqin Qi; Anna Peng; Hong Mei; Yuanyuan Zhang; Ya Zhang; Paiziyeti Tuerxun; Wenli Dong; Chunan Li; Ke Xu; Ruixia Chang; Shaoping Yang; Jianduan Zhang (Environmental Science and Pollution Research, 2022)

Selenium attenuates the association of co-exposure to arsenic, cadmium, and lead with cognitive function among Chinese community-dwelling older adults - Bei-Jing Cheng; Jie Sheng; Hong-Li Wang; Yuan Wang; Hong-Juan Cao; Xiu-De Li; Ting-Ting Zhou; Xiang-Long Meng; Huan-Huan Nie; Su-Fang Wang; Dong-Mei Zhang; Gui-Mei Chen; et al. (Environmental Science and Pollution Research, 2022)

Magnetic Plug Sensor with Bridge Nonlinear Correction Circuit for Oil Condition Monitoring of Marine Machinery - Yuwei Zhang; Jiaju Hong; Haotian Shi; Yucai Xie; Hongpeng Zhang; Shuyao Zhang; Wei Li; Haiquan Chen (Journal of Marine Science and Engineering, 2022)
Diesel engines in marine power systems often work in extreme environments. Oil monitoring technology can guarantee the operational safety of diesel engines. In this paper, a magnetic plug sensor for oil debris monitoring is proposed to improve sensitivity and accuracy. Through finite element analysis, absolute deviation is reduced by optimizing the sensor structure. A bridge nonlinear correction circuit is designed to make sensitivity consistent over the entire scale range, which can facilitate calibration and data processing. In order to reduce noise and amplify the signal effectively, a signal post-processing circuit is adopted as well, which consists of a first stage filter circuit, a second stage filter, an active filter module, and an instrumentation amplifier. Therefore, this magnetic plug sensor exhibits better sensitivity and accuracy. Furthermore, a void test and a dynamic test are carried out to investigate its performance. There is a linear relationship between the voltage and the particle mass for the sensor with a bridge nonlinear correction circuit. The results illustrate a minimum of 0.033 mg iron debris with a 1.647 signal-to-noise ratio. Additionally, it can capture and detect 47 μm particles with a debris capture rate of over 90%, which allows it to excel in early fault diagnosis as well.

Effects of Electron Donors and Acceptors on Cr(VI) Removal in Biotic Fe0 Columns Preloaded with Microorganisms - Weiquan Li; Mingxi Li; Weizhao Yin; Weinan Zhang; Jiawei Zhong; Ping Li; Hong Deng; Jinhua Wu (Water, Air, & Soil Pollution, 2022)

Novel development of VOx–CeOx–WOx/TiO2 catalyst for low-temperature catalytic oxidation of chloroaromatic organics - Yunfeng Ma; Jianwen Lai; Jiayao Wu; Xiaoqing Lin; Hong Yu; Hao Zhang; Angjian Wu; Jisheng Long; Xiaodong Li (Waste Disposal & Sustainable Energy, 2022)

Development and Application of Three-Dimensional Bioprinting Scaffold in the Repair of Spinal Cord Injury - Dezhi Lu; Yang Yang; Pingping Zhang; Zhenjiang Ma; Wentao Li; Yan Song; Haiyang Feng; Wenqiang Yu; Fuchao Ren; Tao Li; Hong Zeng; Jinwu Wang (Tissue Engineering and Regenerative Medicine, 2022)

Promoting Oligodendrocyte Differentiation from Human Induced Pluripotent Stem Cells by Activating Endocannabinoid Signaling for Treating Spinal Cord Injury - Hong Gao; Ying Guo; Sangita Biswas; Jing Li; Haojie Zhang; Zhaolin Chen; Wenbin Deng (Stem Cell Reviews and Reports, 2022)

Evidence in Support of Analogical Reasoning Improvements with Executive Attention Intervention in Healthy Young Adults - Yixuan Lin; Qing Li; Mengke Zhang; Yujie Su; Xiangpeng Wang; Hong Li; Antao Chen (Neuroscience Bulletin, 2022)

Research on time series InSAR monitoring method for multiple types of surface deformation in mining area - Ya-xing Li; Ke-ming Yang; Jian-hong Zhang; Zhi-xian Hou; Shuang Wang; Xin-ming Ding (Natural Hazards, 2022)

Effect and Mechanism of Cotrimoxazole Against Talaromyces marneffei in vitro - Jie Chen; Rongfeng Chen; Wudi Wei; Fengxiang Qin; Xiu Chen; Jinhao He; Hong Zhang; Gang Wang; Minjuan Shi; Tongxue Qin; Yinlu Liao; Yuting Wu; et al. (Mycopathologia, 2022)

FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS - Binbin Zhou; Yilei Zheng; Xiaobing Li; Huifang Dong; Jiaxi Yu; Yang Zou; Min Zhu; Yanyan Yu; Xin Fang; Meihong Zhou; Wei Zhang; Yun Yuan; et al. (Molecular Neurobiology, 2022)

Evaluation of instantaneous impact forces on fixed pipelines from submarine slumps - Xingsen Guo; Xiaolei Liu; Hong Zhang; Minqiang Li; Qianyu Luo (Landslides, 2022)

Phosphorus Fertigation Conferred Lodging Tolerance and Improved Grain Quality in Chenopodium quinoa via Enhanced Root Proliferation and Stalk Strength - Yan Deng; Li Zhao; Sumera Anwar; Li-Guang Zhang; Fahad Shafiq; Hong-Xia Guo; Li-Xia Qin; Mei-Xia Wang; Chuang-Yun Wang (Journal of Soil Science and Plant Nutrition, 2022)

Genome-Wide Identification Reveals the Potential Functions of the bZIP Gene Family in Common Bean (Phaseolus vulgaris) in Response to Salt Stress During the Sprouting Stage - Qi Zhang; Wen-jing Zhang; Zhen-gong Yin; Wei-jia Li; Chun-Yang Xia; Hao-Yue Sun; Yi-Ming Yang; Hong-Bin Wu; Shuo Zhang; Hao-hao Zhao; Wen-Hui Zhang; Yong-xia Guo; et al. (Journal of Plant Growth Regulation, 2022)

Microplastic pollution and its impact on marine microbes in Zhanjiang, China - Qing-Lang Song; Fang-Hong Nie; Di-Hua Zhu; Yun-Li Wei; Min Zhang; Yao Hu; Meng-Meng Chen; Dan-Ju Kang; Zhi-Bao Chen; Hong-Ying Lin; Jin-Jun Chen (Journal of Coastal Conservation, 2022)

Enhance energy supply of largemouth bass (Micropterus salmoides) in gills during acute hypoxia exposure - Qiao Liu; Hong Wang; Jiayu Ge; Jie Luo; Kuo He; Haoxiao Yan; Xin Zhang; Rabia Tahir; Wei Luo; Zhiqiong Li; Song Yang; Liulan Zhao (Fish Physiology and Biochemistry, 2022)

Selenium improved mitochondrial quality and energy supply in the liver of high-fat diet-fed grass carp (Ctenopharyngodon idella) after heat stress - Xiaotian Zhang; Haibo Yu; Xianfang Yan; Pengju Li; Chi Wang; Cheng Zhang; Hong Ji; Qinfeng Gao; Shuanglin Dong (Fish Physiology and Biochemistry, 2022)

Dietary sea buckthorn polysaccharide reduced lipid accumulation, alleviated inflammation and oxidative stress, and normalized imbalance of intestinal microbiota that was induced by high-fat diet in zebrafish Danio rerio - Ying Lan; Chi Wang; Cheng Zhang; Pengju Li; Jinding Zhang; Hong Ji; Haibo Yu (Fish Physiology and Biochemistry, 2022)

Synthesis and characterization of TiO2/ZnO heterostructural composite for ultraviolet photocatalytic degrading DOM in landfill leachate - Bicai Li; Donghai Yuan; Caiyun Gao; Hong Zhang; Zhicheng Li (Environmental Science and Pollution Research, 2022)

Environmental regulations, social networks and corporate green innovation: how do social networks influence the implementation of environmental pilot policies? - Zhijun Li; Runze Zhang; Hong Zhu (Environment, Development and Sustainability, 2022)

Internal Cavitating Flow Distribution and Performance Comparison of a Disc Pump with Radial Straight Blade - Weibin Zhang; Hong Li; Kun Shen; Qifeng Jiang; Bois Gérard (Journal of Marine Science and Engineering, 2022)
Disc pumps with radial straight blade are unconventional designs that have been developed for hard-to-pump mixtures for many industrial applications. They are frequently used in chemical industries, sub-sea petroleum pumping systems with multi-phase media and so on. Due to the radial straight blade arrangement, they may suffer from cavitation onsets when being used under different pressure conditions. To study the influence of cavitation characteristic inside the present disc pump flow passages, experimental data analysis on a radial blade disc pump for a wide flow rate range (0 to 110 m3/h) is obtained. In addition, the Reynolds averaged (RANS) approach using the RNG k-ε turbulence model, is carried out under different working conditions with and without cavitation modelling. Two different pump meshing models are also implemented: the first one without hub and shroud side channels between the discs and the volute casing, the second one with both side channels corresponding to the complete real case geometry. The comparisons between experimental and numerical results reveal first that the complete geometry meshing must be used to recover the experimental performance curve especially at low flow rates whatever the rotational speed. Secondly, the cavitation effect is found to take place in precise locations (straight blade and connection column) inside the impeller at high rotational speed and high flow rates. Their effects correspond to the unexpected performance curve deterioration found for the highest rotational speed and high flow rates. Moreover, with the decrease of the inlet absolute pressure, the cavitation degree becomes serious, and the coupling phenomenon of straight blade cavitation and connection column cavitation is formed, which enlarges the scope and enhances the degree of cavitation. The present study proposes a data reduction procedure when open loop experimental testing procedure is used for specific disc pump design and the importance of the impeller-side channels interactions on head pump decrease at low flow coefficients.

Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy - Chengzhi Han; Xinyi Qian; Xiaorong Ren; Shutian Zhang; Li Hu; Jingyao Li; Yijun Huang; Renhui Huang; Kokwin Ooi; Hong Lin; Chunmei Xia (Molecular Neurobiology, 2022)

Acyloxyacyl hydrolase deficiency induces chronic inflammation and bone loss in male mice - Xu Cheng; Xiaoting Song; Zhiyan Li; Chiting Yuan; Xinhuan Lei; Mingxuan Feng; Zhenghua Hong; Liwei Zhang; Dun Hong (Journal of Molecular Medicine, 2022)

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice - Bo Yang; Zhan Gao; Qi-Shuang Li; Xiang-Ye Zhang; Lan Song; Yi-Ni Wang; Xin-Yue Wang; Lin-Lin Ji; Hong-Liang Xu; Hui Xie; Fu-Kai Feng; Xiao-Ping Li; et al. (Inflammation Research, 2022)

Occurrence and damage of epidemic fungal diseases in middle and late stages of sugarcane growth in Yunnan Province of China - Wen-Feng Li; Xiao-Yan Wang; Hong-Li Shan; Rong-Yue Zhang; Yin-Hu Li; Wen-Jie Lu; Ying-Kun Huang (European Journal of Plant Pathology, 2022)

Hydrogeochemical characterization and water quality assessment in Altay, Xinjiang, northwest China - Juan-Qin Gao; Yang Yu; Deng-Hong Wang; Li-Jun Liu; Wei Wang; Hong-Zhang Dai; Kuang Cen (Environmental Monitoring and Assessment, 2022)

The Development of Environmental Geoscience Contributes to the Construction of Ecological Civilization - Pei Lei; Hong Zhang; Qihang Wu; Ping Li; Bing Wang; Pan Wu (Bulletin of Environmental Contamination and Toxicology, 2022)

Effect of gravel content on the detachment of colluvial deposits in Benggang - Li-ting Zhang; Fang Shuai; Li-bo Chen; Yan-he Huang; Jin-shi Lin; Yue Zhang; Hong-li Ge; Fang-shi Jiang (Journal of Mountain Science, 2022)

Modal Identification of Structures by Eliminating the Effect of the High Ocean Wind - Chun-Xu Qu; Chang-Chong Liu; Xiao-Mei Yang; Hui-Juan Liu; Hong-Nan Li; Yu-Feng Zhang (Journal of Marine Science and Engineering, 2022)
Tropical cyclone is a rapidly rotating storm system with severe excitation such as high wind. This severe excitation may change the performance of structures, such as bridges, wharves and wind turbine structures. It is very necessary to monitor this important change. Modal parameters are the ones to reflect the structural instinct behavior. However, many identification methods assume that the excitation is white noise, which is not the truth during high ocean wind excitation. Therefore, the modal identification method to deal with severe ocean wind excitation should be investigated. This paper proposes an innovative method to eliminate the effect of high ocean wind on modal identification. The formulation to generate an impulse response is described, where the effect of high wind is pointed. Then the elimination method is derived using the wind velocity spectrum and correlation function. After the wind field is simulated, the wind velocities and spectra at all accelerometer positions are obtained. The real impulse response form is obtained. Then, modal identification using the real impulse response is performed. Finally, a practical cable-stayed bridge is employed and modal identification is performed. The results show that the identified modes can reflect structural real behavior.

Effects of climate change on the geographical distribution and potential distribution areas of 35 Millettia Species in China - Kai Zhao; Xuetong Li; Jingru Yang; Zebin Huang; Chunlian Li; Lewen Yao; Zekai Tan; Xianyi Wu; Shiyuan Huang; Yanghe Yuan; Zhengyi Hong; Qiuyang Cai; et al. (Environmental Science and Pollution Research, 2022)

Stem Cell-Derived Exosomes: A New Method for Reversing Skin Aging - Jin-Yan Wu; Sai-Nan Wu; Li-Ping Zhang; Xian-Sheng Zhao; Yue Li; Qu-Yang Yang; Ruo-Yue Yuan; Jian-Lan Liu; Hong-Ju Mao; Ning-Wen Zhu (Tissue Engineering and Regenerative Medicine, 2022)

Isolation and Analysis of Reverse Transcriptase of Ty1-copia-Like Retrotransposons in Sugarcane - Jun-Xian Liu; Jing Liu; Tai-Yi Yang; Li-Min Liu; Li-Hang Qiu; Yi-Jing Gao; Wei-Xing Duan; Jing-Chao Lei; Hong-Jian Liu; Rong-Hua Zhang; Wei-Zhong He; Song Li; et al. (Sugar Tech, 2022)

Identification of serum metabolites enhancing inflammatory responses in COVID-19 - Chen-Song Zhang; Bingchang Zhang; Mengqi Li; Xiaoyan Wei; Kai Gong; Zhiyong Li; Xiangyang Yao; Jianfeng Wu; Cixiong Zhang; Mingxia Zhu; Lei Zhang; Xiufeng Sun; et al. (Science China Life Sciences, 2022)

A cumulative Bayesian network meta-analysis on the comparative efficacy of pharmacotherapies for mania over the last 40 years - Yu Hong; Wenbo Huang; Daiyin Cao; Jilai Xu; Huifan Wei; Jie Zhang; Li Wang (Psychopharmacology, 2022)

Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway - Dongbin Lyu; Fan Wang; Mengke Zhang; Weichieh Yang; Haijing Huang; Qinte Huang; Chenglin Wu; Nuoshi Qian; Meiti Wang; Huanfei Zhang; Sichai Zheng; Jing Chen; et al. (Psychopharmacology, 2022)

Phosphorylation of Truncated Tau Promotes Abnormal Native Tau Pathology and Neurodegeneration - Longfei Li; Yanli Jiang; Gang Wu; Yacoubou Abdoul Razak Mahaman; Dan Ke; Qun Wang; Bin Zhang; Jian-Zhi Wang; Hong-Lian Li; Rong Liu; Xiaochuan Wang (Molecular Neurobiology, 2022)

Tetramethylpyrazine protects neural stem cells against sevoflurane-induced toxicity through Akt/GSK-3β pathway - Yan Feng; Kui Wang; Ning Wang; Pengyu Jia; Lei Zhang; Haozheng Yuan; Pan Lu; Yang Lu; Hong Zhang; Rong Li; Yan Zhang; Qianqian Li; et al. (Metabolic Brain Disease, 2022)

Protective effects of Ulva clathrata derived polyphenols against oxidative stress in lipopolysaccharide-induced RAW 264.7 cells via Nrf2/HO-1 pathway - Jingxia Hong; Ping Huang; Bolun Sun; Jie Mi; Jinjie Zhang; Chao Li; Wenge Yang (Journal of Applied Phycology, 2022)

Dietary supplementation of two indigenous Bacillus spp on the intestinal morphology, intestinal immune barrier and intestinal microbial diversity of Rhynchocypris lagowskii - Xin-yu Lei; Dong-ming Zhang; Qiu-ju Wang; Gui-qin Wang; Yue-hong Li; Yu-rou Zhang; Men-nan Yu; Qi Yao; Yu-ke Chen; Zhi-xin Guo (Fish Physiology and Biochemistry, 2022)

Cumulative risk assessment of dietary exposure to phthalates in pregnant women in Beijing, China - Danping Shan; Tao Zhang; Ludi Li; Yuqing Sun; Di Wang; Yingzi Li; Zheng Yang; Kanglong Cui; Shaowei Wu; Lei Jin; Bo Hong; Xuejun Shang; et al. (Environmental Science and Pollution Research, 2022)

Mrz1, a Novel Mitochondrial Outer Membrane RING Finger Protein, is Degraded Through the Ubiquitin–Proteasome Pathway in Schizosaccharomyces pombe - Zecheng Liu; Pan Zhang; Minjie Li; Limayan A; Guihong Yang; Yao Yu; Hong Lu; Jinjie Shang; Ying Huang (Current Microbiology, 2022)

Differences in small-world networks between methamphetamine and heroin use disorder patients and their relationship with psychiatric symptoms - Yan Liu; Qiang Li; Tianyi Zhang; Lei Wang; Yarong Wang; Jiajie Chen; Jia Zhu; Hong Shi; Wei Wang; Wei Li (Brain Imaging and Behavior, 2022)

Paracandidimonas lactea sp. nov., a urea-utilizing bacterium isolated from landfill - Chu Zhang; Qian Pu; Jun-jie Ying; Ying Chen; Cheng-ze Li; Hang-tao Wu; Bin-jie Wang; Yu-han Zhang; Guo-hong Zeng; Ou Li; Xiu-fang Hu; Cong Sun (Archives of Microbiology, 2022)

Functional analysis, diversity, and distribution of carbendazim hydrolases MheI and CbmA , responsible for the initial step in carbendazim degradation - Mingliang Zhang; Xuekun Bai; Qian Li; Lu Zhang; Qian Zhu; Siyuan Gao; Zhijian Ke; Mingli Jiang; Junqiang Hu; Jiguo Qiu; Qing Hong (Environmental Microbiology, 2022)
Strains Rhodococcus qingshengii djl‐6 and Rhodococcus jialingiae djl‐6‐2 both harbour the typical carbendazim degradation pathway with the hydrolysis of carbendazim to 2‐aminobenzimidazole (2‐AB) as the initial step. However, the enzymes involved in this process are still unknown. In this study, the previous reported carbendazim hydrolase MheI was found in strain djl‐6, but not in strain djl‐6‐2, then another carbendazim hydrolase CbmA was obtained by a four‐step purification strategy from strain djl‐6‐2. CbmA was classified as a member of the amidase signature superfamily with conserved catalytic site residues Ser157, Ser181, and Lys82, while MheI was classified as a member of the Abhydrolase superfamily with conserved catalytic site residues Ser77 and His224. The catalytic efficiency ( k cat / K m ) of MheI (24.0–27.9 μM −1 min −1 ) was 200 times more than that of CbmA (0.032–0.21 μM −1 min −1 ). The mheI gene (plasmid encoded) was highly conserved (>99% identity) in the strains from different bacterial genera and its plasmid encoded flanked by mobile genetic elements. The cmbA gene was highly conserved only in strains of the genus Rhodococcus and it was chromosomally encoded. Overall, the function, diversity, and distribution of carbendazim hydrolases MheI and CbmA will provide insights into the microbial degradation of carbendazim.

Quantitative analysis of lake-cooling effect in Hefei City, China, based on multispectral remote sensing and its response to urban expansion - Xuening Lin; Yuhuan Cui; Shuang Hao; Hong Hong; Man Zhang; Jingdong Zhang; Ruonan Li; Mengyu Liu (Environmental Science and Pollution Research, 2022)

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

A novel irinotecan derivative ZBH-1207 with different anti-tumor mechanism from CPT-11 against colon cancer cells - Dawei Zhao; Di Wu; Gengyue Zhang; Yongqi Li; Weiguo Shi; Bohua Zhong; Hong Yu (Molecular Biology Reports, 2022)

Phylogeny and species diversity in Hygrophorus section Aurei in China - Hong-Yan Huang; Wen-Hao Zhang; Ting Huang; Gabriel Moreno; Yun-Ju Pu; Yu-Guang Fan; Shu-Da Yang; Tie-Zhi Liu; Li-Ping Tang (Mycological Progress, 2022)

Comprehensive profiling of phytochemicals in the fruits of Gardenia jasminoides Ellis and its variety using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry - Xiao Ye; Xiao-Qian Liu; Dong Zhang; Wei-Hong Feng; Yao-Hua Liang; Chun Li; Zhi-Min Wang (Journal of Natural Medicines, 2022)

Formation and evolution of secondary particulate matter during heavy haze pollution episodes in winter in a severe cold climate region of Northeast China - Ye Hong; Junying Sun; Yanjun Ma; Yangfeng Wang; Xiaolan Li; Yunhai Zhang; Ningwei Liu; Deping Zhou (Environmental Science and Pollution Research, 2022)

Phthalate exposure enhances incidence of urinary incontinence: US NHANES, 2003–2004 and 2005–2006 - Xianyanling Yi; Kun Jin; Shi Qiu; Xingyu Xiong; Tianyi Zhang; Ge Peng; Dazhou Liao; Xiaonan Zheng; Hang Xu; Hong Li; Lu Yang; Qiang Wei; et al. (Environmental Science and Pollution Research, 2022)

Flow characteristics in curved open channel with partial suspended vegetation - Qiao-ling Zhang; He-fang Jing; Chun-guang Li; Wei-hong Wang; Wen-sheng Zhang (Journal of Mountain Science, 2022)

Molecular characterization of a novel botourmiavirus with inverted complementary termini from the rice blast fungus Magnaporthe oryzae isolate HF04 - Simnin Shuai; Hong Zheng; Hang Ding; Yao Wang; Jinzhe Li; Fuyu Liu; Fengying Liu; Hongliu An; Shouguo Fang; Songbai Zhang; Qingchao Deng (Archives of Virology, 2022)

Complete genome sequence of a novel virus belonging to the genus Badnavirus in jujube (Ziziphus jujuba Mill.) in China - Baojun Liu; Guoxin Zhang; Danbo Song; Quan Wang; Hong Li; Aixing Gu; Jianyu Bai (Archives of Virology, 2022)

Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors - Li-Ping Shen; Wei Li; Ling-Zhu Pei; Jun Yin; Shu-Tao Xie; Hong-Zhao Li; Chao Yan; Jian-Jun Wang; Qipeng Zhang; Xiao-Yang Zhang; Jing-Ning Zhu (The Cerebellum, 2022)

Effects of Cerebellar Transcranial Direct Current Stimulation in Patients with Stroke: a Systematic Review - Li Hong-yu; Zhang Zhi-jie; Li Juan; Xiong Ting; He Wei-chun; Zhu Ning (The Cerebellum, 2022)

Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy - Huijun Li; Jialin Xu; Yanan Zhang; Lei Hong; Zhijian He; Zhiheng Zeng; Li Zhang (Human Cell, 2022)
Astragaloside IV (AS-IV), as one of the main active components of Astragalus membranaceus , has been reported to have cardiovascular protective effects. However, the role and molecular mechanism of AS-IV in vascular senescence have not been clearly stated. The in vitro aging model was constructed using bleomycin (BLM) in vascular smooth muscle cells (VSMCs). Cell senescence were assessed through Western blotting analysis of aging markers, flow cytometry, and the β-galactosidase (SA-β-Gal) kit. Mitophagy was determined through transmission electron microscopy, TMRM staining, and Western blotting analysis of p62. A model of aging blood vessels was induced by d -gal. The vascular wall thickness of mice was also evaluated by H&E staining. Our data proved that AS-IV plays an anti-senescent role in vitro and in vivo. Results showed that AS-IV effectively improved mitochondrial injury, raised MMP, and mediated mitophagy in BLM-induced senescent VSMCs and d -gal induced aging mice. Parkin expression strengthened AS-IV’s anti-senescent function. In conclusions, AS-IV attenuated BLM-induced VSMC senescence via Parkin to regulate mitophagy. Therefore, AS-IV-mediated Parkin might be a latent therapeutic agent and target for VSMC senescence.

Genetic basis underlying tiller angle in rice (Oryza sativa L.) by genome-wide association study - Shaoxing Bai; Jun Hong; Su Su; Zhikang Li; Wensheng Wang; Jianxin Shi; Wanqi Liang; Dabing Zhang (Plant Cell Reports, 2022)

Updated taxonomy of Chinese Clavaria subg. Syncoryne (Clavariaceae, Agaricales): description of two new species and one newly recorded species - Jun Yan; Gui-Wu Li; Wen-Hao Liu; Zuo-Hong Chen; Ping Zhang (Mycological Progress, 2022)

Chemical and biological diversity of new natural products from marine sponges: a review (2009–2018) - Li-Li Hong; Ya-Fang Ding; Wei Zhang; Hou-Wen Lin (Marine Life Science & Technology, 2022)
Marine sponges are productive sources of bioactive secondary metabolites with over 200 new compounds isolated each year, contributing 23% of approved marine drugs so far. This review describes statistical research, structural diversity, and pharmacological activity of sponge derived new natural products from 2009 to 2018. Approximately 2762 new metabolites have been reported from 180 genera of sponges this decade, of which the main structural types are alkaloids and terpenoids, accounting for 50% of the total. More than half of new molecules showed biological activities including cytotoxic, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, enzyme inhibition, and antimalarial activities. As summarized in this review, macrolides and peptides had higher proportions of new bioactive compounds in new compounds than other chemical classes. Every chemical class displayed cytotoxicity as the dominant activity. Alkaloids were the major contributors to antibacterial, antifungal, and antioxidant activities while steroids were primarily responsible for pest resistance activity. Alkaloids, terpenoids, and steroids displayed the most diverse biological activities. The statistic research of new compounds by published year, chemical class, sponge taxonomy, and biological activity are presented. Structural novelty and significant bioactivities of some representative compounds are highlighted. Marine sponges are rich sources of novel bioactive compounds and serve as animal hosts for microorganisms, highlighting the undisputed potential of sponges in the marine drugs research and development.

Role of host plants in the suitability and dispersal of an omnivorous predator Arma chinensis Fallou (Hemiptera: Pentatomidae: Asopinae) in a biological control context - Ming-Zhen Pan; Zhi-Xiao Fu; Yu-Yan Li; Hong-Yin Chen; Li-Sheng Zhang; Tong-Xian Liu (Journal of Plant Diseases and Protection, 2022)

Aromatic-turmerone ameliorates DSS-induced ulcerative colitis via modulating gut microbiota in mice - Chunlian Li; Weicheng Zhang; Xianyi Wu; Qiuyang Cai; Zekai Tan; Zhengyi Hong; Shiyuan Huang; Yanghe Yuan; Lewen Yao; Lanyue Zhang (Inflammopharmacology, 2022)

The dynamical-statistical subseasonal prediction of precipitation over China based on the BCC new-generation coupled model - Jie Wu; Hong-Li Ren; Peiqun Zhang; Yan Wang; Ying Liu; Chongbo Zhao; Qiaoping Li (Climate Dynamics, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Rs7853346 Polymorphism in lncRNA-PTENP1 and rs1799864 Polymorphism in CCR2 are Associated with Radiotherapy-Induced Cognitive Impairment in Subjects with Glioma Via Regulating PTENP1/miR-19b/CCR2 Signaling Pathway - Sen Yang; Zhan-zhao Fu; Yan-qiu Zhang; Bao-hong Fu; Li-xin Dong (Biochemical Genetics, 2022)

Improving protected area effectiveness through consideration of different human‐pressure baselines - Chun‐Ting Feng; Ming Cao; Fang‐Zheng Liu; Yue Zhou; Jin‐Hong Du; Li‐Bo Zhang; Wen‐Jie Huang; Jian‐Wu Luo; Jun‐Sheng Li; Wei Wang (Conservation Biology, 2022)
Previous assessments of the effectiveness of protected areas (PAs) focused primarily on changes in human pressure over time and did not consider the different human‐pressure baselines of PAs, thereby potentially over‐ or underestimating PA effectiveness. We developed a framework that considers both human‐pressure baseline and change in human pressure over time and assessed the effectiveness of 338 PAs in China from 2010 to 2020. The initial state of human pressure on PAs was taken as the baseline, and changes in human pressure index (HPI) were further analyzed under different baselines. We used the random forest models to identify the management measures that most improved effectiveness in resisting human pressure for the PAs with different baselines. Finally, the relationships between the changes in the HPI and the changes in natural ecosystems in PAs were analyzed with different baselines. Of PAs with low HPI baselines, medium HPI baselines, and high HPI baselines, 76.92% ( n =150), 11.11% ( n =12), and 22.86% ( n =8) , respectively, showed positive effects in resisting human pressure. Overall, ignoring human‐pressure baselines somewhat underestimated the positive effects of PAs, especially for those with low initial human pressure. For PAs with different initial human pressures, different management measures should be taken to improve effectiveness and reduce threats to natural ecosystems. We believe our framework is useful for assessing the effectiveness of PAs globally, and we recommend it be included in the Convention on Biological Diversity Post‐2020 Strategy.

RIG-I acts as a tumor suppressor in melanoma via regulating the activation of the MKK/p38MAPK signaling pathway - Rui Guo; Shun-Yuan Lu; Jin-Xia Ma; Qian-Lan Wang; Lu Zhang; Ling-Yun Tang; Yan Shen; Chun-Ling Shen; Jin-Jin Wang; Li-Ming Lu; Zhu-Gang Wang; Hong-Xin Zhang (Human Cell, 2022)
Studies have indicated that RIG-I may act as a tumor suppressor and participate in the tumorigenesis of some malignant diseases. However, RIG-I induces distinct cellular responses via different downstream signaling pathways depending on the cell type. To investigate the biological function and underlying molecular mechanism of RIG-I in the tumorigenesis of melanoma, we constructed RIG-I knockout, RIG-I -overexpressing B16-F10 and RIG-I knockdown A375 melanoma cell lines, and analyzed the RIG-I-mediated change in the biological behavior of tumor cells in spontaneous and poly (I:C)-induced RIG-I activation. Cell proliferation, cell cycling, apoptosis and migration were detected by CCK-8 assay, BrdU incorporation assay, Annexin V–PI staining assay and Transwell assay, respectively. In vivo tumorigenicity was evaluated by tumor xenograft growth in nude mice and subsequently by Ki67 staining and TUNEL assays. Furthermore, Western blotting was utilized to explore the underlying mechanism of RIG-I in melanoma cells. Our data showed that RIG-I promotes apoptosis and inhibits proliferation by G1 phase cell cycle arrest in the melanoma cell lines. Mechanistically, RIG-I induced the phosphorylation of p38 MAPK and MAPK kinases MKK3 and MKK4. In conclusion, the current study demonstrated that RIG-I suppressed the development of melanoma by regulating the activity of the MKK/p38 MAPK signaling pathway, which is relevant to research on novel therapeutic targets for this malignant disease.

Pharmacokinetics of benapenem for injection in subjects with mild to moderate renal impairment - Haijing Yang; Min Zhang; Yuancheng Chen; Hong Ren; Hong Zhang; Chen Yu; Jianda Lu; Li You; Jicheng Yu; Hong Liang; Cuilan Xiao; Zishuang He; et al. (European Journal of Clinical Pharmacology, 2022)

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

Deep-Sea-Derived Fungi as Valuable Producers of Cytotoxic Secondary Metabolites and Their Leads Potential - Guangrong Zhao; Wenli Tang; Jianlong Zhang; Peimin Shi; Youzhi Li; Jiao Wang; Qingqin Shen; Haixia Si; Linlin Jiang; Xin Yu; Hongwei Zhu; Guozhong Chen; et al. (Frontiers in Marine Science, 2022)
Cancer is the leading lethal disease worldwide. Natural products have contributed significantly to the development of approved therapeutic agents. Therefore, research into new bioactive naturally sourced metabolites with lead potential is urgently needed. It is well-known that marine microorganisms are by far one of the most notable and prolific sources of bioactive natural products. Among them, deep-sea-derived fungi are extraordinarily adapted and metabolically active under extreme environmental conditions, which enable them to produce a large number of novel secondary metabolites. Chemical examination of deep-sea-derived fungi has yielded enormous amounts of cytotoxic natural products and potential drug leads. This review summarizes a total of 229 cytotoxic compounds isolated from deep-sea-derived fungi from 2010 to 2021. The emphasis is on the unique chemical diversity of these metabolic products, together with their relevant cytotoxic properties. Among the isolated metabolites, 82 compounds have been found to possess moderate to potent cytotoxic activities. Meanwhile, we also highlight some compounds with potent cytotoxicities (namely “star molecules”) considering their high drug lead potential. This review reveals deep-sea-derived fungi as considerable resources for the development of new drugs and the potential of the newly discovered secondary metabolites as valuable antitumor lead compounds.

Submarine Optical Fiber Sensing System for the Real-Time Monitoring of Depth, Vibration, and Temperature - Zhengyong Liu; Shengqi Zhang; Chengkun Yang; Weng-Hong Chung; Zhaohui Li (Frontiers in Marine Science, 2022)
Ocean observation becomes increasingly important as the ocean climate changes diversely and the marine disasters (such as tsunamis, typhoon, and earthquakes) occur frequently, which typically requires widespread and reliable monitoring techniques. In such a scenario, this paper presents a submarine optical fiber sensing system to realize real-time monitoring of the environmental parameters. The system consists of an undersea optical interrogation module together with multiple fiber Bragg grating (FBG)-based sensors, particularly for the measurement of depth, vibration, and temperature. The experimentally demonstrated sensitivities of the pressure, temperature, and vibration sensors are -1.993 nm/MPa, 0.08 nm/°C, and 0.139 nm/g (g = 9.8 m/s 2 ), corresponding to the resolutions of 0.25 kPa, 0.006°C, and 0.004 g, respectively, based on the interrogation resolution of ~0.5 pm. To verify the feasibility and reliability of the proposed submarine sensing system, a prototype was developed and a proof test under the sea was conducted in an area close to Pearl River Estuary in China. The achieved results from the sea test show promising accuracy that is comparable to the commercially available electric-based sensors. Good characteristics of the surface water wave were observed by conducting the fast Fourier transform of the measured depth change, which shows a dominant frequency of ~0.25 Hz. The system provides the flexibility of replacing various optical fiber sensors easily and the capability of real-time monitoring in a remote way. The demonstrated submarine sensing system could find potential applications in real-time monitoring of the undersea ecosystem and the environmental evolution where multiparameter sensing is in demand.

Low-carbon production or not? Co-opetition supply chain manufacturers’ production strategy under carbon cap-and-trade policy - Huiqin Zhang; Yuxiang Zhang; Ping Li; Hong Zheng; Zhigang Li (Environment, Development and Sustainability, 2022)

Basic Phenotyping of Male Fertility from 2019 to 2020 at the Human Sperm Bank of Fudan University - Yadong Li; Can Sun; Haitao Ma; Hong Zhu; Feng Zhang; Feng Jiang (Phenomics, 2022)

Primary Cutaneous Mucormycosis, Candida Onychomycosis and Endophthalmitis in a Patient with CARD9 Mutation - Lu Zhang; Jianfeng Huang; Yubo Ma; Zhe Wan; Hong Dai; Ruoyu Li; Heng Gu; Xiaowen Wang (Mycopathologia, 2022)

lncRNA BDNF-AS Attenuates Propofol-Induced Apoptosis in HT22 Cells by Modulating the BDNF/TrkB Pathway - Yu-Hai Xu; Yuan Luo; Jiang-Bei Cao; Yan-Hong Liu; Yu-Xiang Song; Xiao-Ying Zhang; Qiang Fu; Wei-Dong Mi; Hao Li (Molecular Neurobiology, 2022)
Propofol is widely used as an intravenous anesthetic in clinical practice. Previous studies have indicated that propofol induces apoptosis in neurons. Brain-derived neurotrophic factor (BDNF), a neurotrophic factor, is associated with neuronal apoptosis. BDNF-AS, a relatively conserved long non-coding RNA, can reverse the transcription of BDNF. This study aimed to investigate the involvement of BDNF-AS in propofol-induced apoptosis in HT22 cells. HT22 cells were treated with various concentrations of propofol at different time points. BDNF-AS was silenced using BDNF-AS-targeting siRNA. TrkB was antagonized by the TrkB inhibitor, ANA-12. Flow cytometry, quantitative reverse-transcription PCR, and western blotting were performed to analyze apoptosis and the expression of genes and proteins, respectively. In propofol-treated HT22 cells, BDNF-AS was upregulated, and BDNF was downregulated in a time- and dose-dependent manner. BDNF-AS downregulation mediated by siRNA mitigated apoptosis, upregulated the expression of Bcl-2, and downregulated the expression of Bax and caspase-3, 7, and 9. ANA-12 downregulated the expression of Bcl-2, upregulated the expression of Bax and caspase-3, 7, and 9, and increased apoptosis. Our study implied that inhibition of BDNF-AS can decrease propofol-induced apoptosis by activating the BDNF/TrkB pathway. Thus, the BDNF-AS-BDNF/TrkB signaling pathway may be a valuable target for treating propofol-induced neurotoxicity.

Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat - Dong Peng; Han-Zi Qiao; Hong-Yu Tan; Yi-Xue Wang; Dan Luo; Li-Jun Qiao; Ye-Feng Cai; Shi-Jie Zhang; Qi Wang; Li Guan (Metabolic Brain Disease, 2022)

The Association Between Arsenic Metabolism and Hypertension Among Population with Varying Arsenic Exposure Levels in China - Yinqiao Dong; Miao Zhou; Mingming Zhang; Huanhuan Wang; Yao Chen; Xudan Liu; Shuyi Yang; Hong Lang; Guifan Sun; Xin Li (Exposure and Health, 2022)

Response of bacterial communities in saline-alkali soil to different pesticide stresses - Juan Che; Yan Lei Zhu; Yan Hong Li; Rui Zhang; Zhi Yong Ruan; Wei Zhang (Environmental Science and Pollution Research, 2022)

Impact of land cover transformation on urban heat islands in Harbin, China - Stephen Dauda Yabo; Donglei Fu; Bo Li; Xiaofei Shi; Samit Thapa; Xie Shengjin; Lu Lu; Hong Qi; Wei Zhang (Environmental Monitoring and Assessment, 2022)

Different Surface Appearances Caused by Unbalanced Mn2+ Accumulation in Gallstones Consisting of Cholesterol and CaCO3 Obtained from a Patient After Cholecystectomy - Da-Yong Lu; Jin Zhang; Qiao-Li Liu; Hong-Guang Wang; Meng Cui (Biological Trace Element Research, 2022)

Comment on “Relationship of Circulating Copper Level with Gestational Diabetes Mellitus: a Meta-analysis and Systemic Review” - Shu-ping Li; Xiao-ping Zhang; Xin-hong Cui; Li-juan Zhao; Yan-jun Rong (Biological Trace Element Research, 2022)

Risk factors of herpes simplex virus reactivation after surgery for primary trigeminal neuralgia - Xueke Zhen; Xiaoli Xu; Xu Shao; Hong Tian; Jun Xu; Bin Zhu; Ying Zuo; Li Zhang; Yanbing Yu (Journal of NeuroVirology, 2022)

Intelligent identification method and application of seismic faults based on a balanced classification network - Jing Yang; Ren-Wei Ding; Hui-Yong Wang; Nian-Tian Lin; Li-Hong Zhao; Shuo Zhao; Yu-Jie Zhang (Applied Geophysics, 2022)

An integrated belowground trait‐based understanding of nitrogen‐driven plant diversity loss - Qiuying Tian; Peng Lu; Xiufeng Zhai; Ruifang Zhang; Yao Zheng; Hong Wang; Bao Nie; Wenming Bai; Shuli Niu; Peili Shi; Yuanhe Yang; Kaihui Li; et al. (Global Change Biology, 2022)
Belowground plant traits play important roles in plant diversity loss driven by atmospheric nitrogen (N) deposition. However, the way N enrichment shapes plant microhabitats by patterning belowground traits and finally determines aboveground responses is poorly understood. Here, we investigated the rhizosheath trait of 74 plant species in seven N‐addition simulation experiments across multiple grassland ecosystems in China. We found that rhizosheath formation differed among plant functional groups and contributed to changes in plant community composition induced by N enrichment. Compared with forb species, grass and sedge species exhibited distinct rhizosheaths; moreover, grasses and sedges expanded their rhizosheaths with increasing N‐addition rate which allowed them to colonize belowground habitats. Grasses also shaped a different microenvironment around their roots compared with forbs by affecting the physicochemical, biological, and stress‐avoiding properties of their rhizosphere soil. Rhizosheaths act as a “biofilm‐like shield” by the accumulation of protective compounds, carboxylic anions and polysaccharides, determined by both plants and microorganisms. This enhanced the tolerance of grasses and sedges to stresses induced by N enrichment. Conversely, forbs lacked the protective rhizosheaths which renders their roots sensitive to stresses induced by N enrichment, thus contributing to their disappearance under N‐enriched conditions. This study uncovers the processes by which belowground facilitation and trait matching affect aboveground responses under conditions of N enrichment, which advances our mechanistic understanding of the contribution of competitive exclusion and environmental tolerance to plant diversity loss caused by N deposition.

Community Competition Is the Microorganism Feedback to Sedimentary Carbon Degradation Process in Aquaculture Tidal Flats - Min Zhou; Fu-Tao Fang; Cong Zeng; Li-Hong Zhang; Cheng-Xu Zhou; Zhuo-Yi Zhu (Frontiers in Marine Science, 2022)
How the microbial community response to carbon degradation is unclear, while it plays an essential role in predicting microbial community shift and determining carbon cycling. Surface sediments in two contrasting aquacultural tidal flat sites in Fujian Province, China, were collected in October, 2020. In addition to 16s rRNA gene high-throughput sequencing for determining bacteria and archaea biodiversity, an amino acids-based molecular degradation index DI was used to quantify the carbon degradation status. The results revealed that the microorganism response to DI at the family level was community competition. Specifically, the winning microbes that grew under carbon degradation (i.e., operational taxa unit numbers negatively related with the degradation index) accounted for only 18% of the total family number, but accounted for 54% of the total operational taxa unit numbers. Network analysis confirmed the oppressive relation between winners and the rest (losers + centrists), and further suggested the losers survival strategy as uniting the centrists. These findings shed new light on microorganism feedback to carbon degradation, and provide a scientific basis for the explanation of microbial community shift under progressive carbon degradation.

Impact of the evolution of Plateau Lake landscape pattern on ecosystem service value in the Pearl River basin: a case study of Yilong Lake Basin in Yunnan Province, China - Guoqiang Ma; Jianping Xiao; Qiujie Li; Lixun Zhang; Bei An; Guojun Sun; Hua Cheng; Jiaqi Tang; Hong Li (Acta Geophysica, 2022)

Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway - Baoyu Shen; Dongxian Zhang; Xiaofeng Zeng; Lina Guan; Genmeng Yang; Liu Liu; Jian Huang; Yuanyuan Li; Shijun Hong; Lihua Li (Psychopharmacology, 2022)

Identification and functional characterization of safflower cysteine protease 1 as negative regulator in response to low-temperature stress in transgenic Arabidopsis - Hong Yingqi; Yanxi Lv; Jianyi Zhang; Naveed Ahmad; Youbao Li; Nan Wang; Liu Xiuming; Yao Na; Xiaokun Li (Planta, 2022)

Revising the species diversity of Hygrophorus section Olivaceoumbrini s.l. (Hygrophoraceae, Agaricales) in China - Hong-Yan Huang; Wen-Hao Zhang; Ting Huang; Shuai Jiang; Yan-Jia Hao; Man Mu; Li-Ping Tang (Mycological Progress, 2022)

Metagenomic analysis reveals wide distribution of phototrophic bacteria in hydrothermal vents on the ultraslow-spreading Southwest Indian Ridge - Hong Chen; Deng Hui Li; Ai Jun Jiang; Xue Gong Li; Shi Jun Wu; Jian Wei Chen; Meng Jie Qu; Xiao Qing Qi; Jie Dai; Rui Zhao; Wei-Jia Zhang; Shan Shan Liu; et al. (Marine Life Science & Technology, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2 - Jinbao Zong; Yanping Zhang; Fenfen Guo; Changyuan Wang; Hong Li; Gaoyang Lin; Wenqing Jiang; Xiaoping Song; Xiufang Zhang; Feng Huang; Min Qi; Xin Zheng (Journal of Applied Genetics, 2022)

Pathways of soil N2O uptake, consumption, and its driving factors: a review - Hongshan Liu; Yuefen Li; Baobao Pan; Xiangzhou Zheng; Juhua Yu; Hong Ding; Yushu Zhang (Environmental Science and Pollution Research, 2022)

The Status of Polychlorinated Biphenyls (PCBs) Extract from Zhanjiang Mangrove Sediments and the Effects on Tissue Structure and Inflammatory Cytokines in Zebrafish Liver - Aftab Qamar; Javaria Waheed; Sahar Ghulam Mohyuddin; Zhi-Bao Chen; Dan-Ju Kang; Zhang Li; Glen Hay Anthony; Ravi Gooneratne; Fang-Hong Nie; Jin-Jun Chen (Bulletin of Environmental Contamination and Toxicology, 2022)

Transcriptome revealing the dual regulatory mechanism of ethylene on the rhynchophylline and isorhynchophylline in Uncaria rhynchophylla - Xue Li; Xiao-hong Wang; Wei Qiang; Hao-jie Zheng; Li-yang ShangGuan; Ming-sheng Zhang (Journal of Plant Research, 2022)

Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities - Ying-Ying Chen; Jiang-Ping Hou; Ling Huang; Afsar Khan; Fei-Fei Xing; Xiao-Han Zhang; De-Feng Han; Shi-Li Yan; Gui-Dong Cao; Qi-Yang Jiao; Dejie Liu; Xuwei Zhu; et al. (Natural Product Research, 2022)

Two new dammarane-type triterpenoids from the green walnut husks of Juglans mandshurica Maxim - Yuan-Yuan Zhou; Hui-Rui Gao; Hong-Juan Song; Dan-Da Ma; Xiao-Juan Zhang; Yan-Ping Sun; Yan Liu; Xiao-Li Wang; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Quinolizidine alkaloids from the roots of Sophora flavescens - Jian-Chun Li; Zhi-Jun Zhang; Dan Liu; Ming-Yan Jiang; Rong-Tao Li; Hong-Mei Li (Natural Product Research, 2022)

Spatiotemporal distribution of perfluoroalkyl acid in Chinese eggs - Xinxuan Wang; Hong Zhang; Hui Zhao; Jianying Li (Food Additives & Contaminants Part B-Surveillance, 2022)

Dissection of the practical soybean breeding pipeline by developing ZDX1, a high-throughput functional array - Rujian Sun; Bincheng Sun; Yu Tian; Shanshan Su; Yong Zhang; Wanhai Zhang; Jingshun Wang; Ping Yu; Bingfu Guo; Huihui Li; Yanfei Li; Huawei Gao; et al. (Theoretical and Applied Genetics, 2022)
Key message We developed the ZDX1 high-throughput functional soybean array for high accuracy evaluation and selection of both parents and progeny, which can greatly accelerate soybean breeding. Abstract Microarray technology facilitates rapid, accurate, and economical genotyping. Here, using resequencing data from 2214 representative soybean accessions, we developed the high-throughput functional array ZDX1, containing 158,959 SNPs, covering 90.92% of soybean genes and sites related to important traits. By application of the array, a total of 817 accessions were genotyped, including three subpopulations of candidate parental lines, parental lines and their progeny from practical breeding. The fixed SNPs were identified in progeny, indicating artificial selection during the breeding process. By identifying functional sites of target traits, novel soybean cyst nematode-resistant progeny and maturity-related novel sources were identified by allele combinations, demonstrating that functional sites provide an efficient method for the rapid screening of desirable traits or gene sources. Notably, we found that the breeding index (BI) was a good indicator for progeny selection. Superior progeny were derived from the combination of distantly related parents, with at least one parent having a higher BI. Furthermore, new combinations based on good performance were proposed for further breeding after excluding redundant and closely related parents. Genomic best linear unbiased prediction (GBLUP) analysis was the best analysis method and achieved the highest accuracy in predicting four traits when comparing SNPs in genic regions rather than whole genomic or intergenic SNPs. The prediction accuracy was improved by 32.1% by using progeny to expand the training population. Collectively, a versatile assay demonstrated that the functional ZDX1 array provided efficient information for the design and optimization of a breeding pipeline for accelerated soybean breeding.

Distinct co-occurrence patterns and driving forces of abundant and rare bacterial communities in the multispecies solid-state fermentation process of cereal vinegar - Ming-Ye Peng; Zhen-Ming Lu; Xiao-Juan Zhang; Ting Huang; Yong-Jian Deng; Li-Juan Chai; Jin-Song Shi; Zheng-Hong Xu (Systems Microbiology and Biomanufacturing, 2022)

Sodium tanshinone IIA sulfonate improves cognitive impairment via regulating Aβ transportation in AD transgenic mouse model - Hui-Han Ma; Can Wan; Lu-Di Zhang; Rong-Rong Zhang; Dong Peng; Li-Jun Qiao; Shi-Jie Zhang; Ye-Feng Cai; Hong-Qiang Huang (Metabolic Brain Disease, 2022)

Cavin-1 promotes M2 macrophages/microglia polarization via SOCS3 - Wei Huang; Yiyi Hong; Wenjing He; Li Jiang; Wen Deng; Biyan Peng; Fen Tang; Chaolan Shen; Qianqian Lan; Hui Huang; Haibin Zhong; Jian Lv; et al. (Inflammation Research, 2022)

Short-term effect of ambient air pollutant change on the risk of tuberculosis outpatient visits: a time-series study in Fuyang, China - Xin-Qiang Wang; Ying-Qing Li; Cheng-Yang Hu; Kai Huang; Kun Ding; Xiao-Jing Yang; Xin Cheng; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Yong-Zhong Zhang; Zhen-tao Ding; et al. (Environmental Science and Pollution Research, 2022)

Preparatory delta phase response is correlated with naturalistic speech comprehension performance - Jiawei Li; Bo Hong; Guido Nolte; Andreas K. Engel; Dan Zhang (Cognitive Neurodynamics, 2022)

RPTOR methylation in the peripheral blood and breast cancer in the Chinese population - Yifei Yin; Shuifang Lei; Lixi Li; Xiaoqin Yang; Qiming Yin; Tian Xu; Wenjie Zhou; Hong Li; Wanjian Gu; Fei Ma; Rongxi Yang; Zhengdong Zhang (Genes & Genomics, 2022)

Extensive sequence divergence between the reference genomes of Taraxacum kok-saghyz and Taraxacum mongolicum - Tao Lin; Xia Xu; Huilong Du; Xiuli Fan; Qingwen Chen; Chunyan Hai; Zijian Zhou; Xiao Su; Liquan Kou; Qiang Gao; Lingwei Deng; Jinsheng Jiang; et al. (Science China Life Sciences, 2022)

A truncated CC-NB-ARC gene TaRPP13L1-3D positively regulates powdery mildew resistance in wheat via the RanGAP-WPP complex-mediated nucleocytoplasmic shuttle - Xiangyu Zhang; Guanghao Wang; Xiaojian Qu; Mengmeng Wang; Huan Guo; Lu Zhang; Tingdong Li; Yajuan Wang; Hong Zhang; Wanquan Ji (Planta, 2022)

Mungbean VrCOL1 regulates flowering time under short-day conditions in Arabidopsis - Qianqian Zhang; Jing Dong; Zhanqi Wang; Ying Wang; Chunmei Cai; Hong Zhu; Shuai Li (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Study of the Involvement of the P2Y12 Receptor in Chronic Itching in Type 2 Diabetes Mellitus - Xiumei Xu; Huiqing Zhang; Lin Li; Runan Yang; Guilin Li; Shuangmei Liu; Günther Schmalzing; Hong Nie; Shangdong Liang (Molecular Neurobiology, 2022)

MiR-1246 regulates the PI3K/AKT signaling pathway by targeting PIK3AP1 and inhibits thyroid cancer cell proliferation and tumor growth - Jingyan Li; Zhanlei Zhang; Jieting Hu; Xiaoting Wan; Wei Huang; Hong Zhang; Ningyi Jiang (Molecular and Cellular Biochemistry, 2022)
One of the most prevalent forms of endocrine malignancies is thyroid cancer. Herein, we explored the mechanisms whereby miR-1246 is involved in thyroid cancer. Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1) was identified as a potential miR-1246 target, with the online Gene Expression Omnibus (GEO) database. The binding between miR-1246 and PIK3AP1 and the dynamic role of these two molecules in downstream PI3K/AKT signaling were evaluated. Analysis of GEO data demonstrated significant miR-1246 downregulation in thyroid cancer, and we confirmed that overexpression of miR-1246 can inhibit migratory, invasive, and proliferative activity in vitro and tumor growth in vivo. Subsequent studies indicated that miR-1246 overexpression decreased the protein level of PIK3AP1 and the phosphorylation of PI3K and AKT, which were reversed by PIK3AP1 overexpression. At the same time, overexpression of PIK3AP1 also reversed the miR-1246 mimics-induced inhibition proliferative, migratory, and invasive activity, while promoting increases in apoptotic death, confirming that miR-1246 function was negatively correlated with that of PIK3AP1. Subsequently, we found that the miR-1246 mimics-induced inhibition of PI3K/AKT phosphorylation was reversed by the PI3K/AKT activator IGF-1. miR-1246 mimics inhibited proliferative, migratory, and invasive activity while promoting increases in apoptotic death, which were reversed by IGF-1. Furthermore, miR-1246 agomir can inhibit tumor growth in vivo. We confirmed that miR-1246 affects the signaling pathway of PI3K/AKT via targeting PIK3AP1 and inhibits the development of thyroid cancer. Thus, miR-1246 is a new therapeutic target for thyroid cancer.

Vermicompost Application Enhances Halophyte Suaeda salsa Performance and Improves Coastal Saline Soil Quality - Jing-Fang Cai; Xuan-Shao Liu; Kai Sun; Fan Jiang; Ming-Xiang Zhang; Hong-Li Li; Fei-Hai Yu (Journal of Soil Science and Plant Nutrition, 2022)

Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis - Zhuo-Zhi Liang; Yi-Xin Zhang; Rui-Mei Zhu; Yue-Lin Li; Hong-Mei Jiang; Ruo-Bi Li; Qian-Xin Chen; Qing Wang; Lu-Ying Tang; Ze-Fang Ren (Environmental Science and Pollution Research, 2022)

Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China - Tie-Ning Zhang; Qi-Jun Wu; Yan-Hong Huang; Jing Li; Zong-Jiao Chen; Li-Li Li; Yan-Ling Chen; Shu Liu; Cheng-Zhi Jiang; Yu-Hong Zhao (Environmental Science and Pollution Research, 2022)

Effectiveness of Disinfectants Suitable for Inactivating SARS-CoV-2 at Cold-Chain Temperature - Xiaosong Wu; Yin Chen; Ling Wang; Xiling Guo; Lunbiao Cui; Yiming Shen; Fang Li; Hong Sun; Liubo Zhang; Jin Shen; Yan Xu (Food and Environmental Virology, 2022)

Schwann-like cell conditioned medium promotes angiogenesis and nerve regeneration - Jiahong Yu; Kai Ye; Jing Li; Yusheng Wei; Jiqin Zhou; Wei Ni; Lei Zhang; Tianyan Chen; Bin Tang; Hong Xu; Jiabo Hu (Cell and Tissue Banking, 2022)

Caldalkalibacillus salinus sp. nov., isolated from a salt lake in Xinjiang, northwest China - Ting-Hao Ouyang; Man Peng; Zhen Zhang; Wei-Xun Chunyu; Li-Ming Wang; En-Min Zhou; Xu-Hong Gao; Shu-Kun Tang (Archives of Microbiology, 2022)

Can artificial light promote submerged macrophyte growth in summer? - Chao Xu; Hai-Jun Wang; Yan Li; Chi Xu; Qing Yu; Miao Liu; Miao Zhang; Hong-Zhu Wang; David P. Hamilton; Erik Jeppesen (Aquatic Ecology, 2022)

Making of Massoia Lactone-Loaded and Food-Grade Nanoemulsions and Their Bioactivities against a Pathogenic Yeast - Li Yuan; Hong-Qian Zhang; Zhe Chi; Guang-Lei Liu; Zhen-Ming Chi (Journal of Marine Science and Engineering, 2022)
Nanoemulsions (NEs) have been made for improving the delivery and disperse of bioactive compounds. In this study, it was found that the best ingredients for the stable Massoia lactone-loaded and food-grade NEs making were 560.0 µL of Tween-80, 240.0 µL of Span-80 and 200.0 µL of Massoia lactone. Then, 9.0 mL of distilled water was titrated into the mixture under continuous magnetic stirring (750 rotations min−1) with about 2 drops per second for 20 min. Finally, the system was treated by ultrasonication using an ultrasonic generator (180 W and 22 KHz) for 5 min. All the prepared particles with a mean droplet diameter of 43 nm were spherical, had uniform size distribution and were equally distributed in the Massoia lactone-loaded NEs. The obtained Massoia lactone-loaded nanoemulsions (NEs) were very stable without changes of the mean droplet diameter and polydispersity indexes (PDI) for over two months under different conditions. As with free Massoia lactone, Massoia lactone loaded in the NEs had high anti-fungal activity against Metschnikowia bicuspidate LIAO, a pathogenic yeast causing milky disease in the Chinese mitten crab by damaging its cell membrane and causing cellular necrosis. Massoia lactone loaded in the NEs also had the DPPH radical scavenging activity and the hydroxyl radical scavenging activity.

Stilbenoids from the roots of Stemona tuberosa - Hong-Mei Li; Tian-Tian He; Miao Zhang; Jia-Ning Liu; Xue Zhao; Jie Liu; Lei Fang (Natural Product Research, 2022)

White Matter Free Water is a Composite Marker of Cerebral Small Vessel Degeneration - Peiyu Huang; Ruiting Zhang; Yeerfan Jiaerken; Shuyue Wang; Hui Hong; Wenke Yu; Chunfeng Lian; Kaicheng Li; Qingze Zeng; Xiao Luo; Xinfeng Yu; Xiao Wu; et al. (Translational Stroke Research, 2022)

Comparative transcriptome analysis revealed the molecular mechanism of the effect of light intensity on the accumulation of rhynchophylline and isorhynchophylline in Uncaria rhynchophylla - Xiao-Hong Wang; Xue Li; Wei Qiang; Xiao-Song Yu; Hao-Jie Zheng; Ming-Sheng Zhang (Physiology and Molecular Biology of Plants, 2022)

Plant-derived lignans as potential antiviral agents: a systematic review - Xin-Ya Xu; Dong-Ying Wang; Yi-Ping Li; Stephen T. Deyrup; Hong-Jie Zhang (Phytochemistry Reviews, 2022)

Production of dimethyl sulfide and acrylic acid from dissolved dimethylsulfoniopropionate during the growth of Prorocentrum minimum - Pei-Feng Li; Pei-Pei Gao; Chun-Ying Liu; Hong-Hai Zhang; Gui-Peng Yang (Journal of Applied Phycology, 2022)

LINC01087 indicates a poor prognosis of glioma patients with preoperative MRI - Wangsheng Chen; Fei Wang; Jianhua Zhang; Changqing Li; Lan Hong (Functional & Integrative Genomics, 2022)
Long intergenic non-coding RNA 01,087 (LINC01087) has been concerned as an oncogene in breast cancer, while its mechanism in glioma has been little surveyed. Thus, we searched the prognostic value and functional action of LINC01087 in glioma. Glioma patients after preoperative MRI diagnosis were enrolled, and LINC01087, microRNA (miR)-1277-5p, and alkaline ceramidase 3 (ACER3) levels were tested in glioma cancer tissue. The correlation between LINC01087 expression and the survival of patients were analyzed. LINC01087, miR-1277-5p, and ACER3 levels in U251 cells were altered via transfection, and cell malignant phenotypes were monitored. The relationship between miR-1277-5p and LINC01087 or ACER3 was detected. The LINC01087 and ACER3 expression was in up-regulation and the miR-1277-5p expression was in down-regulation in clinical glioma samples. High expression of LINC01087 was associated with poor prognosis of glioma patients with preoperative MRI. LINC01087 silencing restrained tumor malignancy in glioma cells. Mechanistically, LINC01087 directly interacted with miR-1277-5p. ACER3 was a known target of miR-1277-5p. Moreover, rescue assays reveal that miR-1277-5p overexpression (or ACER3 overexpression) reversed the effects of LINC01087 upregulation (or miR-1277-5p upregulation) on glioma cells. LINC01087 has prognostic significance in glioma and silencing LINC01087 deters glioma development through elevating miR-1277-5p to reduce ACER3 expression.

Association between exposure to ambient air pollution and semen quality in adults: a meta-analysis - Hong Qian; Qiaoqiao Xu; Wenkai Yan; Yun Fan; Zhi Li; Chengzhe Tao; Feng Zhang; Chuncheng Lu (Environmental Science and Pollution Research, 2022)

Aberrant functional and effective connectivity of the frontostriatal network in unilateral acute tinnitus patients with hearing loss - Gang-Ping Zhou; Yu-Chen Chen; Wang-Wei Li; Heng-Le Wei; Yu-Sheng Yu; Qing-Qing Zhou; Xindao Yin; Yue-Jin Tao; Hong Zhang (Brain Imaging and Behavior, 2022)

Responses and feedback of litter properties and soil mesofauna to herbaceous plants expansion into the alpine tundra on Changbai Mountain, China - Ying-jie Zhang; Ying-hua Jin; Jia-wei Xu; Hong-shi He; Yan Tao; Zhi-peng Yang; Jing Zhao; Yin-xia Diao; Chen-hui Sun; Mai-He Li (Journal of Mountain Science, 2022)

miR-181b-5p Promotes the Progression of Cholangiocarcinoma by Targeting PARK2 via PTEN/PI3K/AKT Signaling Pathway - Zhe-Long Jiang; Fu-Xing Zhang; Hong-Liang Zhan; He-Jun Yang; Si-Yu Zhang; Zhao-Hui Liu; Yi Jiang; Li-Zhi Lv; Rui-Sheng Ke (Biochemical Genetics, 2022)

Numerical investigation of the control factors driving Zhe-Min Coastal Current - Yang Zhang; Fei Chai; Joseph Zhang; Yang Ding; Min Bao; Yunwei Yan; Hong Li; Wei Yu; Liang Chang (Acta Oceanologica Sinica, 2022)

Two new nor -lignans from Selaginella pulvinata (Hook. & Grev.) Maxim and their antihyperglycemic activities - Hua-Wei Lv; Yu-Xia Li; Meng Luo; Jia-Meng Qi; Ze-Fei Fu; Hong-Jian Zhang; Yuan-Qiang Guo; Chu Chu; Han-Bing Li; Ji-Zhong Yan (Natural Product Research, 2022)

SYL3-k increases style length and yield of F1 seeds via enhancement of endogenous GA4 content in Oryza sativa L. pistils - Xiaojing Dang; Yuanqing Zhang; Yulong Li; Siqi Chen; Erbao Liu; Bingjie Fang; Qiangming Liu; Dong She; Zhiyao Dong; Zhilan Fan; Dalu Li; Hui Wang; et al. (Theoretical and Applied Genetics, 2022)
Key message SYL3-k allele increases the outcrossing rate of male sterile line and the yield of hybrid F 1 seeds via enhancement of endogenous GA 4 content in Oryza sativa L. pistils. The change in style length might be an adaptation of rice cultivation from south to north in the northern hemisphere. Abstract The style length (SYL) in rice is one of the major factors influencing the stigma exertion, which affects the outcross rate of male sterile line and the yield of hybrid F 1 seeds. However, the biological mechanisms underlying SYL elongation remain elusive. Here, we report a map-based cloning and characterisation of the allele qSYL3-k . The qSYL3-k allele encodes a MADS-box family transcription factor, and it is expressed in various rice organs. The qSYL3-k allele increases SYL via the elongation of cell length in the style, which is associated with a higher GA 4 content in the pistil. The expression level of OsGA3ox2 in pistils with qSYL3-k alleles is significantly higher than that in pistils with qSYL3-n allele on the same genome background of Nipponbare. The yield of F 1 seeds harvested from plants with 7001S SYL3−k alleles was 16% higher than that from plants with 7001S SYL3−n allele. The sequence data at the qSYL3 locus in 136 accessions showed that alleles containing the haplotypes qSYL3 AA , qSYL3 AG , and qSYL3 GA increased SYL, whereas those containing the haplotype qSYL3 GG decreased it. The frequency of the haplotype qSYL3 GG increases gradually from the south to north in the northern hemisphere. These findings will facilitate improvement in SYL and yield of F 1 seeds henceforward.

Methyl jasmonate treatment, aphid resistance assay, and transcriptomic analysis revealed different herbivore defensive roles between tobacco glandular and non-glandular trichomes - Zhaojun Wang; Yanhua Li; Hongying Zhang; Xiaoxiao Yan; Hong Cui (Plant Cell Reports, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

Long noncoding RNA XIST modulates microRNA-135/CREB1 axis to influence osteogenic differentiation of osteoblast-like cells in mice with tibial fracture healing - Ying Zhang; Qiang Yuan; Qiushi Wei; Peifeng Li; Zhikun Zhuang; Jitian Li; Youwen Liu; Leilei Zhang; Zhinan Hong; Wei He; Haibin Wang; Wuyin Li (Human Cell, 2022)

Exploratory analysis of the associations between urinary phytoestrogens and thyroid hormones among adolescents and adults in the United States: National Health and Nutrition Examination Survey 2007–2010 - Yun Fan; Hong Qian; Zhuo Wu; Zhi Li; Xiuzhu Li; Yan Zhang; Qiaoqiao Xu; Chuncheng Lu; Xinru Wang (Environmental Science and Pollution Research, 2022)

Microbial controls on heavy metals and nutrients simultaneous release in a seasonally stratified reservoir - Xuecheng Zhang; Shiyuan Ding; Hong Lv; Gaoyang Cui; Mengdi Yang; Yiyao Wang; Tianhao Guan; Xiao-Dong Li (Environmental Science and Pollution Research, 2022)

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells - Xiang-xing Zhu; Jia-sheng Pan; Tao Lin; Ye-cheng Yang; Qiu-yan Huang; Shuai-peng Yang; Zi-xiao Qu; Zi-sheng Lin; Jian-cong Wen; Ai-fen Yan; Juan Feng; Lian Liu; et al. (Biotechnology Letters, 2022)

Different changes in pre- and postsynaptic components in the hippocampal CA1 subfield after transient global cerebral ischemia - Yan Zhang; Bai-Hong Tan; Shuang Wu; Cheng-Hao Wu; Jia-Le Suo; Yue Gui; Cheng-Mei Zhou; Yan-Chao Li (Brain Structure and Function, 2022)

LncSNHG3 promotes hepatocellular carcinoma epithelial mesenchymal transition progression through the miR-152-3p/JAK1 pathway - Hong Li; Yu Wu; Runmei Wang; Junmei Guo; Qin Yu; Lihe Zhang; Haiping Zhao; Hao Yang (Genes & Genomics, 2022)

Subproteomic profiling from renal cortices in OLETF rats reveals mutations of multiple novel genes in diabetic nephropathy - Zhiguo Li; Hong Shen; Yeqiang Liu; Xuefeng Zhou; Meihua Yan; Hailan He; Tingting Zhao; Haojun Zhang; Ping Li (Genes & Genomics, 2022)

Alteribacter salitolerans sp. nov., isolated from a saline-alkaline soil - Shuang Wang; Lei Sun; Manik Prabhu Narsing Rao; Guo-Hong Liu; Pin-Jiao Jin; Zhou-Yan Dong; Zheng-Han Lian; Xiao-Yu Hao; Ming-Yi Zhang; Wen-Jun Li (Archives of Microbiology, 2022)

Streptomyces blattellae, a novel actinomycete isolated from the in vivo of a Blattella germanica - Gui-Min Liu; Lin-Lin Yuan; Li-Li Zhang; Hong Zeng (Antonie van Leeuwenhoek, 2022)

The in vitro and in vivo anti-inflammatory activities of triterpene saponins from Clematis florida - Na-Na Yang; Yi-Fan Zhang; Hai-Tao Zhang; Xin-Hua Ma; Jin-Huang Shen; Peng Li; Tian-Hua Zhong; Yong-Hong Zhang (Natural Product Research, 2021)

Review of the regional nomenclature and tectonic setting for mesozoic gold deposits in the Malanyu Anticline area of Eastern Hebei Province, North China - Leon Bagas; Frank Bierlein; Si-Hong Jiang; Yi-Fei Liu; Li-Li Zhang (International Geology Review, 2021)

Discriminative optimization algorithm with global–local feature for LIDAR point cloud registration - Jia Wang; Ping Wang; Biao Li; Ruigang Fu; Siyi Zhao; Hong Zhang (International Journal of Remote Sensing, 2021)

MicroRNA-197-3p mediates damage to human coronary artery endothelial cells via targeting TIMP3 in Kawasaki disease - Chaowu Liu; Deguang Yang; Hong Wang; Shengwei Hu; Xiaofei Xie; Li Zhang; Hongling Jia; Qi Qi (Molecular and Cellular Biochemistry, 2021)

Hydrogen Sulfide Maintains Good Nutrition and Delays Postharvest Senescence in Postharvest Tomato Fruits by Regulating Antioxidative Metabolism - Ting-Ying Zhong; Gai-Fang Yao; Sha-Sha Wang; Ting-Ting Li; Ke-Ke Sun; Jun Tang; Zhong-Qin Huang; Feng Yang; Yan-Hong Li; Xiao-Yan Chen; Lan-Ying Hu; Hua Zhang; et al. (Journal of Plant Growth Regulation, 2021)

Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology - Yuhong Zhang; Xu Chen; Qiqi Wang; Congcong Du; Wenbin Lu; Hong Yuan; Zhenzhen Zhang; Danqing Li; Xing Ling; Xiang Ren; Yang Zhao; Qi Su; et al. (Journal of Molecular Medicine, 2021)

Characterization of the novel hybrid cultivar E25 of Saccharina japonica in the northern farming region of China - Li Su; Ti Feng Shan; Jing Li; Su Qin Gao; Shao Jun Pang; Xiao Fei Leng; Yan Zhang; Ming Fu Zhang; Hong Tao Gao (Journal of Applied Phycology, 2021)

Genome-wide identification and expression analysis of glycosyltransferase gene family 1 in Quercus robur L. - Jie Zhang; Li-Mei Lin; Wen-Wen Cheng; Xin Song; Yue-Hong Long; Zhao-Bin Xing (Journal of Applied Genetics, 2021)