Ioversol Induced Microglia Proinflammatory Activation and Oxidative Stress in Rats - Tao Li; Lili Zhao; Hong Fan; Zhiyang Chen; Ye Li; Meijuan Dang; Ziwei Lu; Jialiang Lu; Qiao Huang; Heying Wang; Shengxi Wu; Guilian Zhang; et al. (Neurotoxicity Research, 2023)

Distinct cytokine profiles in patients with preeclampsia - Ling Guo; Xiangxin Lan; Shanshan Liu; Lianqiong Xu; Shiqin Zhu; Hong-jin Zhao; Jinlai Meng; Yan Li (Inflammation Research, 2023)

Loss of SUN1 function in spermatocytes disrupts the attachment of telomeres to the nuclear envelope and contributes to non-obstructive azoospermia in humans - Qingxia Meng; Binbin Shao; Dan Zhao; Xu Fu; Jiaxiong Wang; Hong Li; Qiao Zhou; Tingting Gao (Human Genetics, 2023)

Comparison of droplet digital PCR and real‐time quantitative PCR for quantitative detection of the parasitic ciliate Ichthyophthirius multifiliis in the water environment - Guangran Hu; Ke Huang; Weitian Zhou; Runqiu Wang; Weishan Zhao; Hong Zou; Wenxiang Li; Shangong Wu; Ming Li; Guitang Wang (Journal of Fish Diseases, 2023)
Ichthyophthiriasis, caused by the parasitic ciliate Ichthyophthirius multifiliis (Ich), is considered one of the most harmful diseases affecting freshwater fish globally. It can cause mass mortalities of fish in intensive farming systems. In such systems, it is thus necessary to detect and quantify the number of Ich in the water so that control measures can be implemented before Ichthyophthiriasis breaks out. In recent years, molecular diagnostic methods have become increasingly important in aquaculture. Real‐time quantitative polymerase chain reaction (qPCR) and droplet digital polymerase chain reaction (ddPCR) have become robust assays for detecting pathogens. In this study, a set of specific primers and a TaqMan‐minor groove binder probe targeting the small‐subunit rDNA (SSU rDNA) of Ich were developed. They were used in qPCR and ddPCR assays to compare the performance of these two different methods in quantitatively detecting Ich. After optimizing the reaction conditions, both qPCR and ddPCR assays were found to have high linearity and quantitative correlations for standard plasmid DNA. When used for the detection of Ich eDNA in water samples, the qPCR assay had a wider detection range, making it a suitable method to screen for the prevalence of Ichthyophthiriasis. However, the ddPCR approach had higher sensitivity, which would help provide advance notice of the disease in complex water environmental samples.

Ecotoxicity stress and bioaccumulation in Eisenia fetida earthworms exposed to vanadium pentoxide in soil - Shi-qing Zhao; Hong Ni; Ji Li; Shun-hao Ai; Xiao-nan Wang; Xiang-yun Gao; Qian-yun Xu; Zheng-tao Liu (Environmental Science and Pollution Research, 2023)

GSK2795039 prevents RIP1-RIP3-MLKL-mediated cardiomyocyte necroptosis in doxorubicin-induced heart failure through inhibition of NADPH oxidase-derived oxidative stress - Xiao-Juan Zhang; Lu Li; Ai-Ling Wang; Hong-Xia Guo; Hui-Ping Zhao; Rui-Fang Chi; Hui-Yu Xu; Li-Guo Yang; Bao Li; Fu-Zhong Qin; Jia-Pu Wang (Toxicology and Applied Pharmacology, 2023)

New insight into enhanced transport of multi-component porous covalent-organic polymers with alkyl chains as injection agents for levofloxacin removal in saturated sand columns - Aiyuan Jia; Yongsheng Zhao; Zhi Liu; Fangyuan Zhang; Can Shi; Zhisheng Liu; Mei Hong; Yangxue Li (Science of The Total Environment, 2023)

New insights into the microbial-driven metal reductive dissolution for enhanced phosphorus release from iron-rich sludge - Ruo-hong Li; Wei-jun Wang; Ren-xin Zhao; Jia-yu Zhang; Lianpeng Sun; Xiao-yan Li; Bing Li (Journal of Cleaner Production, 2023)

Emergence of lnu(C) variant conferring lincomycin resistance in Campylobacter coli of chicken origin - Wenjun Li; Dian Jiao; Jin Kang; Runhao Yu; Wenbo Zhao; Chunyan Xu; Ruichao Li; Xiang-Dang Du; Hong Yao (International Journal of Food Microbiology, 2023)

Compositional changes of CH, O, and N moieties in petroleum ether-extractable portions from the three-step mild degradation of Dongming lignite - Yan-Jun Li; Wei Zhao; Guang-Hui Liu; Hao-Dong An; Ya-Jun Ma; Yu-Hong Kang; Yong Gao; Ni Bai; Ding-Kai Wang; Xian-Yong Wei; Hong-Cun Bai (Fuel, 2023)

Insight into the conformational and allergenicity alterations of shrimp tropomyosin induced by Sargassum fusiforme polyphenol - Yiming Zhao; Ziye Zhang; Zhenxing Li; Xiu-Min Li; Hao Wang; Hong Lin (Food Research International, 2023)

Impact of A/B-type wheat starch granule ratio on rehydration behavior and cooking quality of noodles and the underlying mechanisms - Jiaying Shang; Bo Zhao; Limin Li; Mei Liu; Jing Hong; Xiangqi Fan; Tengfei Wu; Chong Liu; Xueling Zheng (Food Chemistry, 2023)

Concomitant oxidation of fatty acids other than DHA and EPA plays a role in the characteristic off-odor of fish oil - Yun-Qi Wen; Chang-Hu Xue; Hong-Wei Zhang; Li-Li Xu; Xiao-Han Wang; Shi-Jie Bi; Qian-Qian Xue; Yong Xue; Zhao-Jie Li; Joaquín Velasco; Xiao-Ming Jiang (Food Chemistry, 2023)

The compositional characteristics, influencing factors, effects on wine quality and relevant analytical methods of wine polysaccharides: A review - Hong-Yue Zhai; Si-Yu Li; Xu Zhao; Yi-Bin Lan; Xin-Ke Zhang; Ying Shi; Chang-Qing Duan (Food Chemistry, 2023)

Comparison of tropomyosin released peptide and epitope mapping after in vitro digestion from fish (Larimichthys crocea), shrimp (Litopenaeus vannamei) and clam (Ruditapes philippinarum) through SWATH-MS based proteomics - LiLi Xu; Xiao Mei Zhang; Yun Qi Wen; Jin Long Zhao; Tong Cheng Xu; Ling Yong; Hong Lin; Hong Wei Zhang; Zhen Xing Li (Food Chemistry, 2023)

The protective role of vitamin C on intestinal damage induced by high-dose glycinin in juvenile Rhynchocypris lagowskii Dybowski - Rui Zhu; Zongyu Liu; Minghui Lu; Xueqin Wu; Xueyuan Zhao; Hong-He Wang; Ya-Nan Quan; Li-Fang Wu (Fish & Shellfish Immunology, 2023)

Slab dehydration and magmatism in the Kurile arc as a function of depth: An investigation based on B-Sr-Nd-Hf isotopes - Hong-Yan Li; Chao Xie; Jeffrey G. Ryan; Chuan-Mao Yang; Rui-Peng Zhao; Chao Zhang; Yi-Gang Xu (Chemical Geology, 2023)

Distribution patterns of landslides triggered by the 2022 Ms 6.8 Luding earthquake, Sichuan, China - Jian-qiang Zhang; Zong-ji Yang; Qing-kai Meng; Jiao Wang; Kai-heng Hu; Yong-gang Ge; Feng-huan Su; Bo Zhao; Bo Zhang; Ning Jiang; Yu Huang; Zai-yang Ming; et al. (Journal of Mountain Science, 2023)

Individual tree segmentation and biomass estimation based on UAV Digital aerial photograph - Zhao Sun; Yi-fu Wang; Zhi-dan Ding; Rui-ting Liang; Yun-hong Xie; Rui Li; Hao-wei Li; Lei Pan; Yu-jun Sun (Journal of Mountain Science, 2023)

Effect of molding on the structure and properties of poly(butylene adipate-co-terephthalate)/poly(propylene carbonate)/organically modified montmorillonite nanocomposites - Yang Zhao; Jinqing Lai; Ya Huang; Hong Jiang; Yongrong Sun; Yuyin Li; Yuan Li; Fayong Li; Zhengtang Luo; Dong Xie (Applied Clay Science, 2023)

Glyphosate based-herbicide disrupts energy metabolism and activates inflammatory response through oxidative stress in mice liver - Lei Qi; Yan-Mei Dong; Hong Chao; Peng Zhao; Shu-Li Ma; Gang Li (Chemosphere, 2023)

Ecological toxicity of Cd, Pb, Zn, Hg and regulation mechanism in Solanum nigrum L. - Rui Zhao; Xiufeng Cao; Xinxin Li; Tao Li; Hong Zhang; Xiaowei Cui; Zhaojie Cui (Chemosphere, 2023)

In situ degradation of low-density polyethylene film in irrigation maize field: Thickness-dependent effect - Xiao-Bin Xiong; Ze-Ying Zhao; Peng-Yang Wang; Rui Zhou; Jing Cao; Jing Wang; Kiprotich Wesly; Wen-Li Wang; Ning Wang; Meng Hao; Yi-Bo Wang; Hong-Yan Tao; et al. (Science of The Total Environment, 2023)

2000 years of lake-level fluctuations and human adaptation around China's largest freshwater lake - Huanye Wang; Weiguo Liu; Qin Leng; Lin Yang; Hui Zhao; Jun Yang; Yuwei Chen; Shangbin Xiao; Yunning Cao; Jing Hu; Xiaoke Qiang; Peng Cheng; et al. (Palaeogeography, Palaeoclimatology, Palaeoecology, 2023)

Risks of applying mobilising agents for remediation of arsenic-contaminated soils: Effects of dithionite–EDTA and citric acid on arsenic fractionation, leachability, oral bioavailability/bioaccessibility and speciation - Xiao-Chen Chen; Cong-Cong Yao; Ao Wang; Zeng-Di Zhang; Long-Zhao Chen; Jian-Yu Zhang; Xian-Hua Liu; Hong-Bo Li (Journal of Hazardous Materials, 2023)

Adaptation of bacterial community in maize rhizosphere for enhancing dissipation of phthalic acid esters in agricultural soil - Yu-Hong Huang; Yu-Jie Yang; Xiaolian Wu; Cui-Lan Zhu; Huixiong Lü; Hai-Ming Zhao; Lei Xiang; Hui Li; Ce-Hui Mo; Yan-Wen Li; Quan-Ying Cai; Qing X. Li (Journal of Hazardous Materials, 2023)

Comparative chemical and non-contact bioleaching of ion-adsorption type rare earth ore using ammonium sulfate and metabolites of Aspergillus niger and Yarrowia lipolytica to rationalise the role of organic acids for sustainable processing - Li Shen; Hao Zhou; Qiyuan Shi; Xiaoyu Meng; Yu Zhao; Guanzhou Qiu; Xigang Zhang; Hong Yu; Xiao He; Huajin He; Hongbo Zhao (Hydrometallurgy, 2023)

Comparative metabolomics of flavonoids in twenty vegetables reveal their nutritional diversity and potential health benefits - Han Tao; Yao Zhao; Linying Li; Yuqing He; Xueying Zhang; Ying Zhu; Gaojie Hong (Food Research International, 2023)

Resistance vs. surrender: Different responses of functional traits of soybean and peanut to intercropping with maize - Wei-Ping Zhang; Zhao-Xin Li; Sai-Nan Gao; Hao Yang; Hua-Sen Xu; Xin Yang; Hong-Xia Fan; Ye Su; Surigaoge; Jacob Weiner; Dario Fornara; Long Li (Field Crops Research, 2023)

Predicting ozone formation in petrochemical industrialized Lanzhou city by interpretable ensemble machine learning - Li Wang; Yuan Zhao; Jinsen Shi; Jianmin Ma; Xiaoyue Liu; Dongliang Han; Hong Gao; Tao Huang (Environmental Pollution, 2023)

A water-gating and zinc-sieving lignocellulose nanofiber separator for dendrite-free rechargeable aqueous zinc ion battery - Zhenglin Li; Lei Ye; Guoqiang Zhou; Wangwang Xu; Kangning Zhao; Xiaoman Zhang; Shu Hong; Tongtong Ma; Mei-Chun Li; Chaozheng Liu; Changtong Mei (Chemical Engineering Journal, 2023)

Mimicking the competitive interactions to reduce resistance induction in antibacterial actions - Shuo Zhao; Zheyu Li; Suyao Yin; Qi-dai Chen; Hong-bo Sun; Liping Wen; Lei Jiang; Kai Sun (Chemical Engineering Journal, 2023)

A robust protein-peptide co-assembling nanoformulation (PePCAN) platform with significant cell-entry characteristics for targeted cancer therapy - Xiaoyuan Zhao; Xiang Li; Bo Li; Yao Sun; Yejiao Shi; Huaxing Shen; Fan Wang; Jingjing Li; Farukh Sharopov; Zainiddin Mukhiddinov; Chao Ma; Kai Liu; et al. (Chemical Engineering Journal, 2023)

Photodynamic amplified immune checkpoint-blockade therapy of self-delivery bioregulator via epigenetic reprogramming - Linping Zhao; Chuyu Huang; Rongrong Zheng; Xiaona Rao; Renjiang Kong; Runtian Guan; Zuxiao Chen; Xiyong Yu; Hong Cheng; Shiying Li (Chemical Engineering Journal, 2023)

Chronic hypoxia and Cu2+ exposure induce gill remodeling of largemouth bass through endoplasmic reticulum stress, mitochondrial damage and apoptosis - Qiao Liu; Hong Wang; Jiayu Ge; Lisen Li; Jie Luo; Kuo He; Haoxiao Yan; Xin Zhang; Rabia Tahir; Wei Luo; Shiyi Chen; Zhang Cheng; et al. (Aquatic Toxicology, 2023)

Genome-wide signatures of the geographic expansion and breeding of soybean - Ying-Hui Li; Chao Qin; Li Wang; Chengzhi Jiao; Huilong Hong; Yu Tian; Yanfei Li; Guangnan Xing; Jun Wang; Yongzhe Gu; Xingpeng Gao; Delin Li; et al. (Science China Life Sciences, 2023)

Co-application of biochar and microbial inoculants increases soil phosphorus and potassium fertility and improves soil health and tomato growth - Wei Yang; Yingnan Zhao; Yang Yang; Minshuo Zhang; Xiaoxi Mao; Yanjie Guo; Xiangyu Li; Bu Tao; Yongzhi Qi; Li Ma; Wenju Liu; Bowen Li; et al. (Journal of Soils and Sediments, 2023)

Analysis of Whole Blood and Urine Trace Elements in Children with Autism Spectrum Disorders and Autistic Behaviors - Gang Zhao; Si-jin Liu; Xin-yu Gan; Jun-ru Li; Xiao-xue Wu; Si-yan Liu; Yi-si Jin; Ke-rang Zhang; Hong-mei Wu (Biological Trace Element Research, 2023)
The relationship between trace elements and neurological development is an emerging research focus. We performed a case–control study to explore (1) the differences of 13 trace elements chromium (Cr), manganese (Mn), cobalt (Co), zinc (Zn), arsenic (As), selenium (Se), molybdenum (Mo), cadmium (Cd), stannum (Sn), stibium (Sb), mercury (Hg), titanium (TI), and plumbum (Pb) concentration in whole blood and urine between autism spectrum disorder (ASD) children and their typical development peers, and (2) the association between the 13 trace elements and core behaviors of ASD. Thirty ASD subjects (cases) and 30 age-sex-matched healthy subjects from Baise City, Guangxi Zhuang Autonomous Region, China, were recruited. Element analysis was carried out by inductively coupled plasma-optical emission spectrometry. Autistic behaviors were assessed using Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS), and Children Neuropsychological and Behavior Scale (CNBS). The whole blood concentrations of Mo ( p = 0.004), Cd (0.007), Sn ( p = 0.003), and Pb ( p = 0.037) were significantly higher in the ASD cases than in the controls. Moreover, Se (0.393), Hg (0.408), and Mn (− 0.373) concentrations were significantly correlated between whole blood and urine levels in ASD case subjects. There were significant correlations between whole blood Sb (0.406), Tl (0.365), Mo (− 0.4237), Mn (− 0.389), Zn (0.476), and Se (0.375) levels and core behaviors of ASD. Although the mechanism of trace element imbalance in ASD is unclear, these data demonstrate that core behaviors of ASD may be affected by certain trace elements. Further studies are recommended for exploring the mechanism of element imbalance and providing corresponding clinical treatment measures.

Porewater dissolved inorganic carbon released due to artificial sediment scouring in the Yellow River - Xing-yu Huang; Dong Zhang; Fu-shun Wang; Zhi-qi Zhao; Ai-chun Chen; Jun-wen Zhang; Cong Zhang; Li Wu; Yu-hong Li; Bing-juan Ma; Qi-yan Feng (Applied Geochemistry, 2023)

Evaluating the Genetic Role of Circadian Clock Genes in Parkinson’s Disease - Yaqin Xiang; JuanJuan Huang; Yige Wang; XiuRong Huang; Qian Zeng; Lizhi Li; Yuwen Zhao; Hongxu Pan; Qian Xu; Zhenhua Liu; Qiying Sun; Junling Wang; et al. (Molecular Neurobiology, 2023)

A Review and Perspective of Environmental Disinfection Technology Based on Microwave Irradiation - Liming Liu; Na Wang; Azhar Ali Laghari; Hong Li; Can Wang; Zhenyu Zhao; Xin Gao; Qiang Zeng (Current Pollution Reports, 2023)

A novel hybrid prediction model for PM2.5 concentration based on decomposition ensemble and error correction - Hong Yang; Junlin Zhao; Guohui Li (Environmental Science and Pollution Research, 2023)

Labile and refractory fractions of sedimentary organic carbon off the Changjiang Estuary and its implications for sedimentary oxygen consumption - Yu Cao; Hong Huang; Xu Zhao; Jun Li; Teng Wang; Jun Lin; Zhuo-Yi Zhu (Frontiers in Marine Science, 2023)
Estuarine and coastal area is dynamic zone for both marine carbon and oxygen cycles. There is limited evaluation of the labile and refractory fraction of sedimentary organic carbon and further a lack of attention to the corresponding potential in dissolved oxygen utilization. In this study, we collected sediment samples from the Changjiang estuary and adjacent coastal areas in the East China Sea in June 2019 to reveal the distribution, main controlling factor, and implications of four operational fractions of sediment organic carbon that range from labile to refraction. In the laboratory, we processed and defined the four operational fractions of sedimentary organic carbon, includes 1) pure water extractable carbon (WEC), 2) salt (K2SO4 solution) extractable carbon (SEC), 3) Microbial biomass carbon (MBC; chloroform extractable carbon), and 4) refractory organic carbon (ROC; the acid-processed fraction). We revealed that off the Changjiang Estuary, the bulk sedimentary organic carbon (SOC), WEC, SEC, MBC, and ROC were 9.43 ± 3.07 g/kg, 0.12 ± 0.10 g/kg, 0.16 ± 0.07 g/kg, 1.58 ± 0.45 g/kg, and 4.38 ± 1.95 g/kg, respectively. Sediment grain size played a vital role in constraining the LOC fractions, and samples from aquaculture areas showed extra-higher levels of LOC when compared to samples from the non-aquaculture area. The LOC and MBC fraction showed clear negative relation with dissolved oxygen (DO) in the near bottom waters under high DO background (DO > 5.5 mg/L), whereas in a low DO background (DO < 3-4 mg/L) no clear relation can be found. Based on our observed LOC content and DO concentration in the near bottom waters, the depth of hypoxia in the near bottom waters, which would be caused by a total decomposition of 4 mm of LOC in the top sediment, ranged between 0.3 m to 4.7 m with an average depth of 2 m. This value (2 m) means that sedimentary oxygen consumption would contribute 10% in the occurrence of hypoxia, with the rest contributing from water column respiration. Overall, we used the LOC fraction of sedimentary organic carbon to address the dissolved oxygen consumption in the near bottom waters and further study is needed to evaluate this approach.

CircMAN1A2 contributes to nasopharyngeal carcinoma progression via enhancing the ubiquitination of ATMIN through miR-135a-3p/UBR5 axis - Qian-Qian Dang; Pei-Hong Li; Juan Wang; Jing-Yi Zhao; Su-Nan Zhai; Ying-Juan Zheng; Dao-Ke Yang (Human Cell, 2023)

Immobilization of heavy metals in ceramsite prepared using contaminated soils: Effectiveness and potential mechanisms - Chengming Li; Bing Song; Zhiliang Chen; Zequan Liu; Lei Yu; ZeJian Zhi; Yan Zhao; Hong Wei; Min Song (Chemosphere, 2023)

H3K4me3 as a target of di(2-ethylhexyl) phthalate (DEHP) impairing primordial follicle assembly - Ming-Hao Li; Jun-Jie Wang; Yan-Qin Feng; Xuan Liu; Zi-Hui Yan; Xiao-Jun Zhang; Ya-Xin Wen; Hao-Wei Luo; Lan Li; Massimo De Felici; Ai-Hong Zhao; Wei Shen (Chemosphere, 2023)

Experimental investigation of tunnel temperature field and smoke spread under the influence of a slow moving train with a fire in the carriage - Zhiqiang Zhang; Yinjun Tan; Runlin Hong; Yu Zhao; Heng Zhang; Yuchun Zhang; Zhisheng Li (Tunnelling and Underground Space Technology, 2023)

Mapping Chinese annual gross primary productivity with eddy covariance measurements and machine learning - Xian-Jin Zhu; Gui-Rui Yu; Zhi Chen; Wei-Kang Zhang; Lang Han; Qiu-Feng Wang; Shi-Ping Chen; Shao-Min Liu; Hui-Min Wang; Jun-Hua Yan; Jun-Lei Tan; Fa-Wei Zhang; et al. (Science of The Total Environment, 2023)

Stilbenes with potent cytotoxicity from the seedcases of Paeonia suffruticosa Andrews - Meng-Yue Yang; Zhao-Xiang Shao; Yue-Tong Wang; Yong-Lian Hou; Ding-Kang Zhu; Sha Chen; Ya-Hui Zhang; Fei Cao; Yong-Kui Jing; Bin Lin; Zhan-Lin Li; Da-Hong Li; et al. (Phytochemistry, 2023)

Modeling study on the roles of the deposition and transport of PM2.5 in air quality changes over central-eastern China - Lei Zhang; Jianjun He; Sunling Gong; Xiaomei Guo; Tianliang Zhao; Huizheng Che; Hong Wang; Chunhong Zhou; Jingyue Mo; Ke Gui; Yu Zheng; Lei Li; et al. (Journal of Environmental Sciences, 2023)

Early Paleozoic collision-related structures in the Tarim Craton, NW China: Implications for the Proto-Tethys evolution - Yue-Jun Li; Yong-Jin Gao; Hui Zhou; Guang-Ya Zhang; Lei Wen; Yan Zhao; Cheng Li; Duo-Ming Zheng; Ya-Lei Liu; Hong-Hui Li; Cai-Ming Luo; Tong-Fei Huang; et al. (Journal of Asian Earth Sciences, 2023)

A chemometric study on the identification of 5-methylfurfural and 2-acetylfuran as particular volatile compounds of oxidized fish oil based on SHS-GC-IMS - Yun-Qi Wen; Hong-Wei Zhang; Chang-Hu Xue; Xiao-Han Wang; Shi-Jie Bi; Li-Li Xu; Qian-Qian Xue; Yong Xue; Zhao-Jie Li; Joaquín Velasco; Xiao-Ming Jiang (Food Chemistry, 2023)

Impact of wheat starch granule size on viscoelastic behaviors of noodle dough sheet and the underlying mechanism - Jiaying Shang; Bo Zhao; Chong Liu; Limin Li; Jing Hong; Mei Liu; Xiaohui Zhang; Yiming Lei; Xueling Zheng (Food Hydrocolloids, 2023)

Properties and microstructure of pickering emulsion synergistically stabilized by silica particles and soy hull polysaccharides - Guilan Zhao; Shengnan Wang; Yangyang Li; Lina Yang; Hong Song (Food Hydrocolloids, 2023)

Freeze-thaw stability and rheological properties of high internal phase emulsions stabilized by phosphorylated perilla protein isolate: Effect of tea saponin concentration - Qiaoli Zhao; Xin Hong; Liuping Fan; Yuanfa Liu; Jinwei Li (Food Hydrocolloids, 2023)

Solid-liquid interface adsorption of antibiotic resistance plasmids induced by nanoplastics aggravates gene pollution in aquatic ecosystems - Zhiheng Li; Mengjun Wang; Hong Fang; Zhangchao Yao; Huijun Liu; Wenlu Zhao; Jie Chen (Environmental Pollution, 2023)

One-step fabrication of self-healing poly(thioctic acid) coatings on ZE21B Mg alloys for enhancing corrosion resistance, anti-bacterial/oxidation, hemocompatibility and promoting re-endothelialization - Zhao-Qi Zhang; Pei-Duo Tong; Li Wang; Zheng-Hui Qiu; Jing-An Li; Hang Li; Shao-Kang Guan; Cun-Guo Lin; Hong-Yan Wang (Chemical Engineering Journal, 2023)

High performance carbon dioxide electroreduction in ionic liquids with in situ shell-isolated nanoparticle-enhanced Raman spectroscopy - Ye Hu; Zhongdong Gan; Shixian Xin; Wenhui Fang; Min Li; Yanlei Wang; Wei Cui; Hong Zhao; Zengxi Li; Xiangping Zhang (Chemical Engineering Journal, 2023)

Passivation of positively charged cationic defects in perovskite with nitrogen-donor crown ether enabling efficient perovskite solar cells - Yuxuan Yang; Tao Zhao; Ming-Hua Li; Xiaoxue Wu; Mingyue Han; Shih-Chi Yang; Qiaoling Xu; Lede Xian; Xiang Chi; Ning-Jiu Zhao; Hong Cui; Sihan Li; et al. (Chemical Engineering Journal, 2023)

Efficient H2 production in a novel separator electrode assembly (SEA) microbial electrolysis cell - Na Zhao; Dawei Liang; Hong Liu; Shujuan Meng; Xiaohu Li (Chemical Engineering Journal, 2023)

Building a satisfactory indoor environment for healthcare facility occupants: A literature review - Xiumei Shen; Hong Zhang; Ying Li; Kaichen Qu; Liang Zhao; Guangyan Kong; Wenzhao Jia (Building and Environment, 2023)

Lower expression of the equine maternally imprinted gene IGF2R is related to the slow proliferation of hinny embryonic fibroblast in vitro - Xisheng Wang; Nairag Asgenbaatar; Yingchao Shen; Minna Yi; Bilig Zhao; Hong Ren; Toli Davshilt; Tseweendolmaa Ulaangerel; Min Wang; Als Burenbaatar; Shuyue Tian; Bei Li; et al. (Molecular Biology Reports, 2023)

Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease - Li-Sha Ran; Ya-Zeng Wu; Yi-Wen Gan; Hong-Lian Wang; Li-Juan Wu; Chun-Mei Zheng; Yao Ming; Ran Xiong; Yong-Lin Li; Shi-Hang Lei; Xue Wang; Xiao-Qing Lao; et al. (Journal of Natural Medicines, 2023)
Excessive intrahepatocellular lipid accumulation or steatosis is caused by abnormal lipid metabolism and a common character of nonalcoholic fatty liver disease (NAFLD), which may progress into cirrhosis and hepatocellular cancer. Andrographolide (Andro) is the primary active ingredient extracted from Andrographis paniculata , showing a protective role against dietary steatosis with the mechanism not fully understood. In this study, we showed that administration of Andro (50, 100, and 200 mg/kg/day for 8 weeks, respectively) attenuated obesity and metabolic syndrome in high-fat diet (HFD)-fed mice with improved glucose tolerance, insulin sensitivity, and reduced hyperinsulinemia, hyperglycemia, and hyperlipidemia. HFD-fed mice presented hepatic steatosis, which was significantly prevented by Andro. In vitro, Andro decreased the intracellular lipid droplets in oleic acid-treated LO2 cells. The selected RT-PCR array revealed a robust expression suppression of the fatty acid transport proteins (FATPs) by Andro treatment. Most importantly, we found that Andro consistently reduced the expression of FATP2 in both the oleic acid-treated LO2 cells and liver tissues of HFD-fed mice. Overexpression of FATP2 abolished the lipid-lowering effect of Andro in oleic acid-treated LO2 cells. Andro treatment also reduced the fatty acid uptake in oleic acid-treated LO2 cells, which was blunted by FATP2 overexpression. Collectively, our findings reveal a novel mechanism underlying the anti-steatosis effect of Andro by suppressing FATP2-mediated fatty acid uptake, suggesting the potential therapeutic application of Andro in the treatment of NAFLD. Graphical abstract

Solar ring mission: Building a panorama of the Sun and inner-heliosphere - Yuming Wang; Xianyong Bai; Changyong Chen; Linjie Chen; Xin Cheng; Lei Deng; Linhua Deng; Yuanyong Deng; Li Feng; Tingyu Gou; Jingnan Guo; Yang Guo; et al. (Advances in Space Research, 2023)

Cultivation of fish ciliate parasites: Progress and prospects - Ming Li; Giana Bastos Gomes; Weishan Zhao; Guangran Hu; Ke Huang; Tomoyoshi Yoshinaga; Theodore G. Clark; Wenxiang Li; Hong Zou; Shangong Wu; Guitang Wang (Reviews in Aquaculture, 2023)
Ciliates are considered the most harmful parasites of fish, causing mass mortalities and thus substantial economic losses to the aquaculture and ornamental fish industries. To better elucidate their pathogenic mechanisms and facilitate the development of effective prevention and control strategies, it is essential to apply novel technologies to ensure the continuous and sufficient supply of parasite specimens. This review discusses the latest research progress in the artificial culture of six important parasitic ciliates affecting both freshwater and marine fish globally: Ichthyophthirius multifiliis , Cryptocaryon irritans , Chilodonella ( C. hexasticha , C. piscicola and C. uncinata ), Balantidium ctenopharyngodoni , Scuticociliatida gen. spp., and Tetrahymena spp. Methods for in vitro and in vivo culture as well as cryopreservation/preservation (depending on the specific species) of these organisms are described herein. Challenges and future applications of parasite culture are also discussed.

Cover Image - Ming Li; Giana Bastos Gomes; Weishan Zhao; Guangran Hu; Ke Huang; Tomoyoshi Yoshinaga; Theodore G. Clark; Wenxiang Li; Hong Zou; Shangong Wu; Guitang Wang (Reviews in Aquaculture, 2023)

Protein Arginine Methyltransferase 5 Is Necessary for Embryonic Development in Medaka Oryzias latipes - Xiaoting Liang; Shi Duan; Qing Yang; Xiaoqin Ma; Zhenyu Li; Qiting Yao; Kongyue Wu; Pei Chang; Gongqing Feng; Wentao Hong; Mengxi Cao; Qingchun Zhou; et al. (Fishes, 2022)
Protein arginine methyltransferase 5 (Prmt5), conserved from yeast to humans, catalyzes arginine’s dimethylation in proteins. Prmt5 is necessary for embryonic development in mice because it maintains embryonic stem cells. However, the embryos of zebrafish (Danio rerio) remain viable with a deficiency in germ cells and sexual development after the knockout of prmt5. Therefore, it was considered whether prmt5 is dispensable during embryogenesis in fish. Medaka (Oryzias latipes), another model fish organism, was used in this experiment. The medaka prmt5 was mutated with Transcription Activator-Like Effector Nucleases (TALEN) causing the premature stopping of transcription. None of the homozygous prmt5 mutant fish were viable, only the heterozygous offspring survived. Quantitative reverse transcription-polymerase chain reaction (qPCR) results showed a significant decrease in octamer-binding transcription factor 4 (oct4), homeobox transcription factor nanog (nanog), vasa, B-cell CLL/lymphoma 2 (bcl2), and the ratio of bcl2 to bax (bcl2 associated x), and a significant increase in caspase3 and caspase8 in the embryos of the heterozygous prmt5 mutant compared with that of the wild type. The results showed that the mutation of prmt5 caused down-regulation of the genes functioning in stemness and up-regulation of the genes in the cascade of cell death. These results suggested that prmt5 is necessary for embryogenesis via maintaining stemness and repressing apoptosis in medaka.

Transplantation of Nasal Olfactory Mucosa Mesenchymal Stem Cells Benefits Alzheimer’s Disease - Chun-Gu Hong; Meng-Lu Chen; Ran Duan; Xin Wang; Zhi-Lin Pang; Li-Te Ge; Ming Lu; Hui Xie; Zheng-Zhao Liu (Molecular Neurobiology, 2022)

Phosphorus Fertigation Conferred Lodging Tolerance and Improved Grain Quality in Chenopodium quinoa via Enhanced Root Proliferation and Stalk Strength - Yan Deng; Li Zhao; Sumera Anwar; Li-Guang Zhang; Fahad Shafiq; Hong-Xia Guo; Li-Xia Qin; Mei-Xia Wang; Chuang-Yun Wang (Journal of Soil Science and Plant Nutrition, 2022)

Genome-Wide Identification Reveals the Potential Functions of the bZIP Gene Family in Common Bean (Phaseolus vulgaris) in Response to Salt Stress During the Sprouting Stage - Qi Zhang; Wen-jing Zhang; Zhen-gong Yin; Wei-jia Li; Chun-Yang Xia; Hao-Yue Sun; Yi-Ming Yang; Hong-Bin Wu; Shuo Zhang; Hao-hao Zhao; Wen-Hui Zhang; Yong-xia Guo; et al. (Journal of Plant Growth Regulation, 2022)

Enhance energy supply of largemouth bass (Micropterus salmoides) in gills during acute hypoxia exposure - Qiao Liu; Hong Wang; Jiayu Ge; Jie Luo; Kuo He; Haoxiao Yan; Xin Zhang; Rabia Tahir; Wei Luo; Zhiqiong Li; Song Yang; Liulan Zhao (Fish Physiology and Biochemistry, 2022)

Assessment of the Bioavailability of Mercury Sulfides in Paddy Soils Using Sodium Thiosulfate Extraction - Results from Microcosm Experiments - Hong Li; Yunyun Li; Wenli Tang; Huan Zhong; Jiating Zhao; Xu Bai; Shengnan Sha; Diandou Xu; Pei Lei; Yuxi Gao (Bulletin of Environmental Contamination and Toxicology, 2022)

A histological study of vascular wall resident stem cells in venous malformations - Hou-Fu Xia; Wen-Qiang Lai; Gao-Hong Chen; Ye Li; Qi-Hui Xie; Yu-Lin Jia; Gang Chen; Yi-Fang Zhao (Cell and Tissue Research, 2022)

Preservation of soil organic carbon in coastal wetlands promoted by glomalin–iron–organic carbon ternary system - Bo Zhao; Yunlong Jia; Shengjie Wu; Lili Wei; Jian Li; Hualong Hong; Chongling Yan; Mark A. Williams; Qiang Wang (Limnology and Oceanography, 2022)
Iron‐bound soil organic carbon (Fe‐bound SOC) and microbial residues are vital for SOC preservation, a process crucial for drawdown of anthropogenic carbon. However, the relative importance of Fe‐bound SOC in coastal wetlands, and its interaction with microbial residues remain poorly understood. Here, we used glomalin as a proxy for microbial residues, with the goal of determining microbial residues binding to Fe and Fe‐bound SOC across a 1000 km coastline of China including seven typical mangrove wetlands. As hypothesized, it was found that the glomalin fraction was strongly associated with and likely bound to Fe‐bound SOC complexes, which accounted for 21.4% ± 1.6% of mangrove SOC. Mean level of Fe‐bound glomalin was 1.2 ± 0.1 mg cm −3 , accounting for 40.6% ± 1.5% of total glomalin and 35.4% ± 3.2% of Fe‐bound SOC in the top 10 cm mangrove soil layer at regional scale. Due to the growing realization that Fe may be a crucial factor of glomalin cycling, we performed multiple chemical characterization techniques to identify the association between Fe and glomalin. Our results suggested that association to Fe was a main stabilization mechanism of glomalin in soils, and glomalin served as organic ligands in the formation of Fe‐bound SOC. We also found that the bulk glomalin extracts were a glomalin–Fe–OC ternary complex, which constituted an important proportion of mangrove SOC. These findings highlight the important effect of glomalin bound to Fe as a major mechanism of SOC persistence in coastal wetlands.

Effects of climate change on the geographical distribution and potential distribution areas of 35 Millettia Species in China - Kai Zhao; Xuetong Li; Jingru Yang; Zebin Huang; Chunlian Li; Lewen Yao; Zekai Tan; Xianyi Wu; Shiyuan Huang; Yanghe Yuan; Zhengyi Hong; Qiuyang Cai; et al. (Environmental Science and Pollution Research, 2022)

Stem Cell-Derived Exosomes: A New Method for Reversing Skin Aging - Jin-Yan Wu; Sai-Nan Wu; Li-Ping Zhang; Xian-Sheng Zhao; Yue Li; Qu-Yang Yang; Ruo-Yue Yuan; Jian-Lan Liu; Hong-Ju Mao; Ning-Wen Zhu (Tissue Engineering and Regenerative Medicine, 2022)

Identification of serum metabolites enhancing inflammatory responses in COVID-19 - Chen-Song Zhang; Bingchang Zhang; Mengqi Li; Xiaoyan Wei; Kai Gong; Zhiyong Li; Xiangyang Yao; Jianfeng Wu; Cixiong Zhang; Mingxia Zhu; Lei Zhang; Xiufeng Sun; et al. (Science China Life Sciences, 2022)

Local and remote forcing on the interannual variations of the sedimentary δ15N in Santa Barbara Basin during the past 80 years - Hanyue Xu; Da-Wei Li; Hong-Chun Li; Meixun Zhao; William M. Berelson; Gui’e Jin; Li Li; Satabdi Misra (Frontiers in Marine Science, 2022)
Sedimentary nitrogen isotope (δ 15 N sed ) in Santa Barbara Basin (SBB) has been mostly interpreted as the record of the eastern tropical North Pacific (ETNP) intermediate water denitrification process. Nevertheless, debate remains regarding sources and control mechanisms of δ 15 N sed signal in SBB. Multi-proxy analyses including δ 15 N sed , total organic carbon (TOC), total nitrogen (TN), C/N ratio, and marine biomarkers were performed on a 46-cm sediment core (SBB-190629) collected from SBB in 2019. The core was dated with varve counting and 210 Pb dating method, showing a depositional history of 1938–2019 CE with a sedimentation rate of 0.564 cm/year. The findings show that the δ 15 N sed record (at ~0.25-year resolution) ranges from 6.24‰ to 7.43‰, which was affected by both local and remote forcing. The long-term variations of the SBB δ 15 N sed signature show a general decreasing trend from 1940 to the late 1980s, low values during 1980~2000, and an increase afterward, which is thought to reflect changes in ETNP denitrification induced by the strength of tropical trade winds. Our results also reveal a series of abrupt annual to multiannual changes, superimposed on the long-term variation mentioned above. The SBB local δ 15 N signal (Δδ 15 N SBB ) is accessed by using the deviation from the mean δ 15 N (Δδ 15 N) of SBB-190629 to subtract the Δδ 15 N of the ETNP. The Δδ 15 N SBB record compares well with redox-sensitive proxies (Re/Mo ratio and C 29 stanol/stenol ratio) from the SBB bottom water and with the OC marine content calculated based on the C/N ratio mixing model, indicating that the Δδ 15 N SBB is mainly controlled by bottom water denitrification, which was induced by the change of upwelling intensity and marine productivity. Since various climatic factors (e.g., El Niño–Southern Oscillation (ENSO), Pacific Decadal Oscillation (PDO), and North Pacific Gyre Oscillation (NPGO)) have different impacts on the upwelling intensity (hence the marine productivity and denitrification) in SBB on different timescales, the influence of combined climatic factors on SBB denitrification is time dependent.

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Anthocyanins identification and transcriptional regulation of anthocyanin biosynthesis in purple Brassica napus - Hong Fu; Hongbo Chao; Xuejie Zhao; Haoyi Wang; Huaixin Li; Weiguo Zhao; Tao Sun; Maoteng Li; Jinyong Huang (Plant Molecular Biology, 2022)

A novel irinotecan derivative ZBH-1207 with different anti-tumor mechanism from CPT-11 against colon cancer cells - Dawei Zhao; Di Wu; Gengyue Zhang; Yongqi Li; Weiguo Shi; Bohua Zhong; Hong Yu (Molecular Biology Reports, 2022)

Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline - Liangcai Zhao; Haowei Jiang; Jiaojiao Xie; Danjie Shen; Qingqing Yi; Jiapin Yan; Chen Li; Hong Zheng; Hongchang Gao (Molecular Neurobiology, 2022)

A new hybrid prediction model of PM2.5 concentration based on secondary decomposition and optimized extreme learning machine - Hong Yang; Junlin Zhao; Guohui Li (Environmental Science and Pollution Research, 2022)

Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors - Li-Ping Shen; Wei Li; Ling-Zhu Pei; Jun Yin; Shu-Tao Xie; Hong-Zhao Li; Chao Yan; Jian-Jun Wang; Qipeng Zhang; Xiao-Yang Zhang; Jing-Ning Zhu (The Cerebellum, 2022)

Overexpression of TaLAX3-1B alters the stomatal aperture and improves the salt stress resistance of tobacco - Luhua Li; Dingli Hong; Chang An; Yuxuan Chen; Pengpeng Zhao; Xin Li; Fumin Xiong; Mingjian Ren; Ruhong Xu (Molecular Biology Reports, 2022)

The dynamical-statistical subseasonal prediction of precipitation over China based on the BCC new-generation coupled model - Jie Wu; Hong-Li Ren; Peiqun Zhang; Yan Wang; Ying Liu; Chongbo Zhao; Qiaoping Li (Climate Dynamics, 2022)

Rs7853346 Polymorphism in lncRNA-PTENP1 and rs1799864 Polymorphism in CCR2 are Associated with Radiotherapy-Induced Cognitive Impairment in Subjects with Glioma Via Regulating PTENP1/miR-19b/CCR2 Signaling Pathway - Sen Yang; Zhan-zhao Fu; Yan-qiu Zhang; Bao-hong Fu; Li-xin Dong (Biochemical Genetics, 2022)

Interannual Variations of D14CTOC and Elemental Contents in the Laminated Sediments of the Santa Barbara Basin During the Past 200 Years - Hong-Chun Li; Yiwei Chang; William M. Berelson; Meixun Zhao; Satabdi Misra; Tzu-Tsen Shen (Frontiers in Marine Science, 2022)
A 51-cm core (SBB-8-2012) from the depo-center of Santa Barbara Basin (SBB), California has been dated by 210 Pb dating and varve counting, spanning a depositional history during 1815-2011 CE. A total of 89 AMS 14 C measurements on samples from 66 horizons, including animal cartilage, shell and total organic carbon (TOC) in the sediments show apparent 14 C ages between 500 and 4000 yr BP. Among these AMS dates, D 14 C values measured in 78 samples from 62 horizons vary in the range of -64.3‰ to -383.8‰. The 14 C TOC ages much older than predicted from our sedimentation model are influenced by the input of terrigenous sediments, changes in ocean circulation, biological input and carbon remineralization. Three strong old 14 C TOC excursions at 1964~69, 1884~87 and 1819~21 CE indicate higher old carbon input caused by some unusual events (e.g., oil spill, flood event and earthquake). On multi-decadal timescales, the D 14 C TOC shifts in three zones were mainly caused by changes in fossil carbon emission from the seafloor, fraction of marine productivity to terrigenous input of organic carbon (OC) and the atmospheric nuclear bomb testing input of 14 C into the SBB. On interannual to decadal timescales, variations of D 14 C TOC correspond to El Niño-Southern Oscillation effects. During the La Niña period, stronger upwelling and northerly California Current bring nutrient-enriched water into SBB and lead to higher productivity hence more marine OC with higher D 14 C TOC . In addition, reduced terrigenous input of OC with lower D 14 C under less coastal rainfall during La Niña could further elevate the D 14 C TOC . Lower scanning XRF (K+Ti)/2 (indicating lower terrigenous input), higher scanning XRF Sr/Ti as well as acid-leachable elements (reflecting higher biogenic components), and higher D 14 C TOC occur during La Niña. During the El Niño period, the phenomena are opposite. Spectrum analyses of the Southern Oscillation Index (SOI) and the D 14 C TOC as well as the comparison of SOI and SBB-8-2012 records support our scenarios.

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

Air quality assessment and Gray model prediction for the 2022 Winter Olympics in Zhangjiakou, China - Mi Wang; Wenhui Zhao; Lingjun Li; Tong Liu; Lili Wang; Nanchi Shen; Jianming Hong; Wenji Zhao; Zhuowei Hu (Air Quality, Atmosphere & Health, 2022)

Deep-Sea-Derived Fungi as Valuable Producers of Cytotoxic Secondary Metabolites and Their Leads Potential - Guangrong Zhao; Wenli Tang; Jianlong Zhang; Peimin Shi; Youzhi Li; Jiao Wang; Qingqin Shen; Haixia Si; Linlin Jiang; Xin Yu; Hongwei Zhu; Guozhong Chen; et al. (Frontiers in Marine Science, 2022)
Cancer is the leading lethal disease worldwide. Natural products have contributed significantly to the development of approved therapeutic agents. Therefore, research into new bioactive naturally sourced metabolites with lead potential is urgently needed. It is well-known that marine microorganisms are by far one of the most notable and prolific sources of bioactive natural products. Among them, deep-sea-derived fungi are extraordinarily adapted and metabolically active under extreme environmental conditions, which enable them to produce a large number of novel secondary metabolites. Chemical examination of deep-sea-derived fungi has yielded enormous amounts of cytotoxic natural products and potential drug leads. This review summarizes a total of 229 cytotoxic compounds isolated from deep-sea-derived fungi from 2010 to 2021. The emphasis is on the unique chemical diversity of these metabolic products, together with their relevant cytotoxic properties. Among the isolated metabolites, 82 compounds have been found to possess moderate to potent cytotoxic activities. Meanwhile, we also highlight some compounds with potent cytotoxicities (namely “star molecules”) considering their high drug lead potential. This review reveals deep-sea-derived fungi as considerable resources for the development of new drugs and the potential of the newly discovered secondary metabolites as valuable antitumor lead compounds.

Prediction of disability-free survival in healthy older people - Johannes Tobias Neumann; Le T. P. Thao; Anne M. Murray; Emily Callander; Prudence R. Carr; Mark R. Nelson; Rory Wolfe; Robyn L. Woods; Christopher M. Reid; Raj C. Shah; Anne B. Newman; Jeff D. Williamson; et al. (GeroScience, 2022)
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)

Comment on “Relationship of Circulating Copper Level with Gestational Diabetes Mellitus: a Meta-analysis and Systemic Review” - Shu-ping Li; Xiao-ping Zhang; Xin-hong Cui; Li-juan Zhao; Yan-jun Rong (Biological Trace Element Research, 2022)

Continuous cropping of alfalfa (Medicago sativa L.) reduces bacterial diversity and simplifies cooccurrence networks in aeolian sandy soil - Yanxia Xu; Junjie Liu; Xuefeng Liu; Hong Li; Zhao Yang; Hongbao Wang; Xinyu Huang; Lan Lan; Yutong An; Lujun Li; Qin Yao; Guanghua Wang (Soil Ecology Letters, 2022)

Qipengyuania thermophila sp. nov., isolated from a Chinese hot spring - Zi-Yu Zhao; Ting-Ting Xia; Jian-Yu Jiao; Lan Liu; Qing-Yang Su; Meng-Meng Li; Ai-Ping Lv; Yu-Ting Ouyang; Wen-Jun Li; Hong Ming (Archives of Microbiology, 2022)

Intelligent identification method and application of seismic faults based on a balanced classification network - Jing Yang; Ren-Wei Ding; Hui-Yong Wang; Nian-Tian Lin; Li-Hong Zhao; Shuo Zhao; Yu-Jie Zhang (Applied Geophysics, 2022)

Fishery Resources, Ecological Environment Carrying Capacity Evaluation and Coupling Coordination Analysis: The Case of the Dachen Islands, East China Sea - Hong Huang; Zuanyi Wang; Yingdong Li; Xu Zhao; Zhenhua Wang; Xiaopeng Cheng (Frontiers in Marine Science, 2022)
Impacts of human activity on the sustainable development of marine fisheries have been greatly concerned, and the carrying capacity with theoretic and practical meanings has become a focused area over the past two decades. More importantly, there are few studies on the fishery resources and environment compound system. In this study, based on the investigation data in Dachen Islands during 2019–2021, we proposed the evaluation method of fishery resources and ecological environment carrying capacity (FRCC & MEECC) and analyzed the coupling coordination degree between the fishery resources and environment. The results showed that (1) the MEECC of Dachen Islands was in the critical overload state and fluctuated significantly among seasons and the winter voyage of 2021 was the worst. (2) The nekton index of Dachen Islands was basically stable, the fish eggs and juvenile index dropped markedly, and the FRCC was also critically overloaded. (3) The fishery resources and marine environment were moderately balanced. Further, the development was relatively synchronized in autumn of 2019 and 2020, while the fishery resources in spring of 2021 lagged behind the marine environment.

PdeHCA2 affects biomass in Populus by regulating plant architecture, the transition from primary to secondary growth, and photosynthesis - Biligen-Gaowa Zhao; Guo Li; Yue-Feng Wang; Zhen Yan; Feng-Qin Dong; Ying-Chang Mei; Wei Zeng; Meng-Zhu Lu; Hong-Bin Li; Qing Chao; Bai-Chen Wang (Planta, 2022)

Metagenomic analysis reveals wide distribution of phototrophic bacteria in hydrothermal vents on the ultraslow-spreading Southwest Indian Ridge - Hong Chen; Deng Hui Li; Ai Jun Jiang; Xue Gong Li; Shi Jun Wu; Jian Wei Chen; Meng Jie Qu; Xiao Qing Qi; Jie Dai; Rui Zhao; Wei-Jia Zhang; Shan Shan Liu; et al. (Marine Life Science & Technology, 2022)

Geochronology and geochemistry of Late Triassic intrusions in the Liaodong Peninsula, eastern North China Craton: implications for post-collisional lithospheric thinning - Chen Wang; Zheng-Hong Liu; Gang Li; Xiao-Jie Dong; Shi-Chao Li; Qing-Ying Zhao (International Geology Review, 2022)

Spatiotemporal distribution of perfluoroalkyl acid in Chinese eggs - Xinxuan Wang; Hong Zhang; Hui Zhao; Jianying Li (Food Additives & Contaminants Part B-Surveillance, 2022)

The impact of particulate matter 2.5 on the risk of hepatocellular carcinoma: a meta-analysis - Zeng-Hong Wu; Meng Zhao; Hong Yu; Hua-Dong Li (International Archives of Occupational and Environmental Health, 2022)

Alternaria species causing leaf spot on hemp (Cannabis sativa) in Northern China - Hong Cheng; Lin Zhao; Xin Wei; Xi Liu; Guo-Yang Gao; Jian-Xin Deng; Mei-Jia Li (European Journal of Plant Pathology, 2022)

Electrochemical enhancement of high-efficiency wet removal of mercury from flue gas - Nai-jiao Xu; Sen Li; Yu-hong Fu; Zhao-yang Wang; Li-juan Feng; Ji Wang (Environmental Science and Pollution Research, 2022)

Correction to: Role of HMGB1 in TNF-α Combined with Z-VAD-fmk-Induced L929 Cells Necroptosis - Zhao Lei; Can Yu; Xia Li; Li-Hua Huang; Zhi-Qiang Li; Hong-Wei Zhu; Duo Han; Hui Huang; Xiao Yu (Biochemical Genetics, 2022)

Role of HMGB1 in TNF-α Combined with Z-VAD-fmk-Induced L929 Cells Necroptosis - Can Yu; Zhao Lei; Xia Li; Li-Hua Huang; Zhi-Qiang Li; Hong-Wei Zhu; Duo Han; Hui Huang; Xiao Yu (Biochemical Genetics, 2022)

Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China - Tie-Ning Zhang; Qi-Jun Wu; Yan-Hong Huang; Jing Li; Zong-Jiao Chen; Li-Li Li; Yan-Ling Chen; Shu Liu; Cheng-Zhi Jiang; Yu-Hong Zhao (Environmental Science and Pollution Research, 2022)

Impacts of late-spring North Eurasian soil moisture variation on summer rainfall anomalies in Northern East Asia - Yinghan Sang; Hong-Li Ren; Yi Deng; Xiaofeng Xu; Xueli Shi; Shuo Zhao (Climate Dynamics, 2022)

Land development suitability analysis for transport planning evaluation and optimization in mountainous ecological region - Gao-ru Zhu; Man Wang; Qi-li Li; Jie Liu; Yan-ni Zhao; Jia-wei Gao; Hong-lei Xu (Journal of Mountain Science, 2022)

Stilbenoids from the roots of Stemona tuberosa - Hong-Mei Li; Tian-Tian He; Miao Zhang; Jia-Ning Liu; Xue Zhao; Jie Liu; Lei Fang (Natural Product Research, 2022)

The influences of α-hemolytic Streptococcus on class switching and complement activation of human tonsillar cells in IgA nephropathy - Muyao Ye; Chang Wang; Ling Li; Qiulan Zhao; Youming Peng; Hong Liu (Immunologic Research, 2022)

Delayed body development with reduced triglycerides levels in leptin transgenic pigs - Yubo Qing; Muhammad Ameen Jamal; Dejia Shi; Sumei Zhao; Kaixiang Xu; Deling Jiao; Heng Zhao; Honghui Li; Baoyu Jia; Haizhen Wang; Hong-Ye Zhao; Hong-Jiang Wei (Transgenic Research, 2022)

Responses and feedback of litter properties and soil mesofauna to herbaceous plants expansion into the alpine tundra on Changbai Mountain, China - Ying-jie Zhang; Ying-hua Jin; Jia-wei Xu; Hong-shi He; Yan Tao; Zhi-peng Yang; Jing Zhao; Yin-xia Diao; Chen-hui Sun; Mai-He Li (Journal of Mountain Science, 2022)

miR-181b-5p Promotes the Progression of Cholangiocarcinoma by Targeting PARK2 via PTEN/PI3K/AKT Signaling Pathway - Zhe-Long Jiang; Fu-Xing Zhang; Hong-Liang Zhan; He-Jun Yang; Si-Yu Zhang; Zhao-Hui Liu; Yi Jiang; Li-Zhi Lv; Rui-Sheng Ke (Biochemical Genetics, 2022)

Stereumamides E-H, four new minor quaternary ammonium hybrids from Stereum hirsutum - Qian-Yi Hu; Yuan-Chang Duan; Xue-Juan Pu; Su-Su Li; Guo-Hong Li; Pei-Ji Zhao (Natural Product Research, 2022)

LncSNHG3 promotes hepatocellular carcinoma epithelial mesenchymal transition progression through the miR-152-3p/JAK1 pathway - Hong Li; Yu Wu; Runmei Wang; Junmei Guo; Qin Yu; Lihe Zhang; Haiping Zhao; Hao Yang (Genes & Genomics, 2022)

Subproteomic profiling from renal cortices in OLETF rats reveals mutations of multiple novel genes in diabetic nephropathy - Zhiguo Li; Hong Shen; Yeqiang Liu; Xuefeng Zhou; Meihua Yan; Hailan He; Tingting Zhao; Haojun Zhang; Ping Li (Genes & Genomics, 2022)

Discriminative optimization algorithm with global–local feature for LIDAR point cloud registration - Jia Wang; Ping Wang; Biao Li; Ruigang Fu; Siyi Zhao; Hong Zhang (International Journal of Remote Sensing, 2021)

Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology - Yuhong Zhang; Xu Chen; Qiqi Wang; Congcong Du; Wenbin Lu; Hong Yuan; Zhenzhen Zhang; Danqing Li; Xing Ling; Xiang Ren; Yang Zhao; Qi Su; et al. (Journal of Molecular Medicine, 2021)

Genome-wide identification and expression analysis of glycosyltransferase gene family 1 in Quercus robur L. - Jie Zhang; Li-Mei Lin; Wen-Wen Cheng; Xin Song; Yue-Hong Long; Zhao-Bin Xing (Journal of Applied Genetics, 2021)

The spatiotemporal distribution and potential risk assessment of 19 phthalate acid esters in wastewater treatment plants in China - Shaojing Sun; Jimin Shen; Bo Li; Jialu Geng; Lixin Ma; Hong Qi; Anping Zhang; Zebin Zhao (Environmental Science and Pollution Research, 2021)

A novel thermophilic β-carotene 15,15′-monooxygenase with broad substrate specificity from the marine bacterium Candidatus Pelagibacter sp. HTCC7211 - Zhangde Long; Yuzhe Zhao; Yun Xue; Min Wang; Jigang Li; Zan Su; Jiansheng Sun; Qibin Liu; Hong Liu; Duobin Mao; Tao Wei (Biotechnology Letters, 2021)

Two new phenylpropanoids and a new dihydrostilbenoid from the flower buds of Magnolia biondii pamp and their acetylcholinesterase inhibitory activities - Yan-Gang Cao; Hong-Wei Li; Bing Cao; Jian-Chao Wang; Yan-Li Zhang; Xuan Zhao; Xiao-Ke Zheng; Wei-Sheng Feng (Natural Product Research, 2021)

Peripheral CD4+ T cell signatures in predicting the responses to anti-PD-1/PD-L1 monotherapy for Chinese advanced non-small cell lung cancer - Liliang Xia; Hui Wang; Mingjiao Sun; Yi Yang; Chengcheng Yao; Sheng He; Huangqi Duan; Weimin Xia; Ruiming Sun; Yaxian Yao; Zhiwei Chen; Qiong Zhao; et al. (Science China Life Sciences, 2021)

Isolation, Identification and Characterization of Paenibacillus pabuli E1 to Explore Its Aflatoxin B1 Degradation Potential - Gen Li; Xiaoyu Li; Liming Dong; Caixia Li; Panpan Zou; Muhammas Kashif Saleemi; Bilal Murtaza; Bowen Jin; Hong Zhao; Lili Wang; Shuying Li; Huan Yang; et al. (Current Microbiology, 2021)

Regional brain network and behavioral alterations in EGR3 gene transfected rat model of schizophrenia - Wenwen Gao; Guangfei Li; Xiaowei Han; Zeyu Song; Shuai Zhao; Feiyi Sun; Hong Ma; Ailing Cui; Yige Wang; Xiuxiu Liu; Yue Chen; Lu Zhang; et al. (Brain Imaging and Behavior, 2021)

LncRNA MALAT1 Functions as a Competing Endogenous RNA to Regulate BMI1 Expression by Sponging miR-200c/miR-203 in the Control of the Differentiation of Pulp Cells - Hong Jin; Junhai Zhao; Cheng Li (Biochemical Genetics, 2021)

Ambient climate determines the directional trend of community stability under warming and grazing - Peipei Liu; Wangwang Lv; Jianping Sun; Caiyun Luo; Zhenhua Zhang; Xiaoxue Zhu; Xingwu Lin; Jichuang Duan; Guangping Xu; Xiaofeng Chang; Yigang Hu; Qiaoyan Lin; et al. (Global Change Biology, 2021)
Changes in ecological processes over time in ambient treatments are often larger than the responses to manipulative treatments in climate change experiments. However, the impacts of human‐driven environmental changes on the stability of natural grasslands have been typically assessed by comparing differences between manipulative plots and reference plots. Little is known about whether or how ambient climate regulates the effects of manipulative treatments and their underlying mechanisms. We collected two datasets, one a 36‐year long‐term observational dataset from 1983 to 2018, and the other a 10‐year manipulative asymmetric warming and grazing experiment using infrared heaters with moderate grazing from 2006 to 2015 in an alpine meadow on the Tibetan Plateau. The 36‐year observational dataset shows that there was a nonlinear response of community stability to ambient temperature with a positive relationship between them due to an increase in ambient temperature in the first 25 years and then a decrease in ambient temperature thereafter. Warming and grazing decreased community stability with experiment duration through an increase in legume cover and a decrease in species asynchrony, which was due to the decreasing background temperature through time during the 10‐year experiment period. Moreover, the temperature sensitivity of community stability was higher under the ambient treatment than under the manipulative treatments. Therefore, our results suggested that ambient climate may control the directional trend of community stability while manipulative treatments may determine the temperature sensitivity of the response of community stability to climate relative to the ambient treatment. Our study emphasizes the importance of the context dependency of the response of community stability to human‐driven environmental changes.

Pinocembrin Promotes OPC Differentiation and Remyelination via the mTOR Signaling Pathway - Qi Shao; Ming Zhao; Wenwen Pei; Yingyan Pu; Mingdong Liu; Weili Liu; Zhongwang Yu; Kefu Chen; Hong Liu; Benqiang Deng; Li Cao (Neuroscience Bulletin, 2021)

Experimental study of displacement field of layered soils surrounding laterally loaded pile based on transparent soil - Bingxiang Yuan; Zihao Li; Zuqing Zhao; Hong Ni; Zhilei Su; Zhijie Li (Journal of Soils and Sediments, 2021)

Influencing factors and physiochemical changes of embryogenesis through in vitro isolated microspore culture in Brassica species - Yan-Qi Dong; Yu-Hong Gao; Te Zhao; Guang-Qian Ren; Yan-Li Liu; Bin Guan; Rong-Xian Jin; Fei Gao; Yan-Li Zhang; Xiu-Fang Tan; Hong-Cai Zhu; Yu-Hong Zhang; et al. (Biologia, 2021)

Correlation of CD38 expression with the progression of hemorrhagic fever with renal syndrome - Han-Dong Zhao; Yan-Ping Li; Wei-Wei Zhao; Peng Li; Hong-Li Liu (Archives of Virology, 2021)

Alpha-Lipoic Acid Attenuates Cadmium- and Lead-Induced Neurotoxicity by Inhibiting Both Endoplasmic-Reticulum Stress and Activation of Fas/FasL and Mitochondrial Apoptotic Pathways in Rat Cerebral Cortex - Yan Yuan; Shi Wen Zhao; Shuang Quan Wen; Qiao Ping Zhu; Li Wang; Hui Zou; Jian Hong Gu; Xue Zhong Liu; Jian Chun Bian; Zong Ping Liu (Neurotoxicity Research, 2021)

Psychological and occupational impact on healthcare workers and its associated factors during the COVID-19 outbreak in China - Xiaodan Zhang; Ye Jiang; Hu Yu; Yafen Jiang; Qiongfeng Guan; Weihe Zhao; Yingying Mao; Danfeng Huang; Wenke Hong; Da Li (International Archives of Occupational and Environmental Health, 2021)

Construction of high density genetic map and QTL mapping in sorghum × sudangrass - Peng Jin; Lihua Wang; Wenjie Zhao; Jian Zheng; Yi-Hong Wang; Yanlong Liu; Ruirui Meng; Jichao Dai; Lei Zhou; Jieqin Li (Euphytica, 2021)

Maternal exposure to sulfur dioxide and the risk of oral clefts in Liaoning Province, China: a population-based case-control study - Fang-Hua Liu; Ze Xing; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; et al. (Environmental Science and Pollution Research, 2021)

Safety evaluation and ibuprofen removal via an Alternanthera philoxeroides-based biochar - Yuan-da Du; Xin-qian Zhang; Li Shu; Yu Feng; Cui Lv; Hong-qiang Liu; Fei Xu; Qian Wang; Cong-cong Zhao; Qiang Kong (Environmental Science and Pollution Research, 2021)

Three new 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones and one new dimeric 2-(2-phenylethyl)chromone from agarwood of Aquilaria crassna Pierre ex Lecomte in Laos - Yang-Mei Zhao; Li Yang; Fan-Dong Kong; Wen-Hua Dong; Wei Li; Hui-Qin Chen; Hao Wang; Cai-Hong Cai; Cui-Juan Gai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

DNA Methyltransferase 1 Is Dysregulated in Parkinson’s Disease via Mediation of miR-17 - Hong-Qiu Zhang; Jian-Yong Wang; Zhao-Feng Li; Lei Cui; Shi-Shi Huang; Lan-Bing Zhu; Yue Sun; Rui Yang; Hui-Hui Fan; Xiong Zhang; Jian-Hong Zhu (Molecular Neurobiology, 2021)

Roles of bulk and rhizosphere denitrifying bacteria in denitrification from paddy soils under straw return condition - Ning Wang; Ya-Hui Zhao; Jian-Guang Yu; Li-Hong Xue; Hong-Bo Li; Lin-Zhang Yang (Journal of Soils and Sediments, 2021)

Inhibition of the p38 MAPK pathway attenuates renal injury in pregnant rats with acute necrotizing pancreatitis - Jiacheng Zhang; Fangchao Mei; Liang Zhao; Teng Zuo; Yupu Hong; Man Li; Jia Yu; Weixing Wang (Immunologic Research, 2021)

Performance of VITEK 2, E-test, Kirby–Bauer disk diffusion, and modified Kirby–Bauer disk diffusion compared to reference broth microdilution for testing tigecycline susceptibility of carbapenem-resistant K. pneumoniae and A. baumannii in a multicenter study in China - Dandan Yin; Yan Guo; Min Li; Wenjuan Wu; Jin Tang; Ying Liu; Feng Chen; Yuxing Ni; Jingyong Sun; Hong Zhang; Hu Zhao; Fupin Hu (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Ground roll separation method via threshold filtering and constraint of seismic wavelet support in curvelet domain - De-ying Wang; Li-hua Chen; Lie-qian Dong; Li-hong Zhao; Ren-wei Ding; Cheng-zhen Ding (Applied Geophysics, 2021)

Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020 - Encheng Sun; Zhenjiang Zhang; Zilong Wang; Xijun He; Xianfeng Zhang; Lulu Wang; Wenqing Wang; Lianyu Huang; Fei Xi; Haoyue Huangfu; Ghebremedhin Tsegay; Hong Huo; et al. (Science China Life Sciences, 2021)

Overexpression of ring finger protein 20 inhibits the progression of liver fibrosis via mediation of histone H2B lysine 120 ubiquitination - Shanshan Chen; Xuan Dai; Hong Li; Yuhan Gong; Yueyue Zhao; Haijun Huang (Human Cell, 2021)

Effective means to alleviate the greenhouse effect: case study of history match simulations on a brief CO2 injection into less-deep low-rank coal seams - Shuaiwu Gou; Hong Li; Jianyu Li; Yu Zhao (Arabian Journal of Geosciences, 2021)

Subcellular Localization of the D27 Protein in Sugarcane (Saccharum spp. Hybrids) Using an Optimized Protoplast Isolation, Purification, and Transient Gene Expression Protocol - Zhuan-di Wu; Xin Hu; Feng-gang Zan; Yong-bao Pan; David M. Burner; Zheng-ying Luo; Jia-yong Liu; Li-ping Zhao; Li Yao; Yong Zhao; Xin-long Liu; Hong-ming Xia; et al. (Sugar Tech, 2021)

DeepMapi: a Fully Automatic Registration Method for Mesoscopic Optical Brain Images Using Convolutional Neural Networks - Hong Ni; Zhao Feng; Yue Guan; Xueyan Jia; Wu Chen; Tao Jiang; Qiuyuan Zhong; Jing Yuan; Miao Ren; Xiangning Li; Hui Gong; Qingming Luo; et al. (Neuroinformatics, 2021)
The extreme complexity of mammalian brains requires a comprehensive deconstruction of neuroanatomical structures. Scientists normally use a brain stereotactic atlas to determine the locations of neurons and neuronal circuits. However, different brain images are normally not naturally aligned even when they are imaged with the same setup, let alone under the differing resolutions and dataset sizes used in mesoscopic imaging. As a result, it is difficult to achieve high-throughput automatic registration without manual intervention. Here, we propose a deep learning-based registration method called DeepMapi to predict a deformation field used to register mesoscopic optical images to an atlas. We use a self-feedback strategy to address the problem of imbalanced training sets (sampling at a fixed step size in nonuniform brains of structures and deformations) and use a dual-hierarchical network to capture the large and small deformations. By comparing DeepMapi with other registration methods, we demonstrate its superiority over a set of ground truth images, including both optical and MRI images. DeepMapi achieves fully automatic registration of mesoscopic micro-optical images, even macroscopic MRI datasets, in minutes, with an accuracy comparable to those of manual annotations by anatomists.

Mannheimia bovis sp. nov., Isolated from a Dead Cow with Hemorrhagic Pneumonia - Fuxiang Li; Wenhua Zhao; Qionghua Hong; Qingyong Shao; Jianbo Zhu; Shibiao Yang (Current Microbiology, 2021)

Haplotype networks of Phycocalidia tanegashimensis (Bangiales, Rhodophyta) indicate a probable invasion from the South China Sea to Brazil - Wan Zhao; Lei Dong; Dang Diem Hong; Juliet Brodie; Wei-Zhou Chen; Dam Duc Tien; Wei Zhou; Qin-Qin Lu; Mei-Ru Zhang; Li-En Yang (Marine Biodiversity, 2021)

Adaptive Evolution of Chalcone Isomerase Superfamily in Fagaceae - Li-Mei Lin; Hong-Yu Guo; Xin Song; Duo-Duo Zhang; Yue-Hong Long; Zhao-Bin Xing (Biochemical Genetics, 2021)

Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells - Fa-Wu Dong; Fang Li; Jia-Jia Ren; Cheng-Mei Zhao; Hong-Li Diao; Bao-Jing Li; Yan-Ping Li; Jiang-Miao Hu; Hong-Ping He (Natural Product Research, 2021)

Correction to: P2Y12 receptor upregulation in satellite glial cells is involved in neuropathic pain induced by HIV glycoprotein 120 and 2',3'-dideoxycytidine - Zhihua Yi; Lihui Xie; Congfa Zhou; Huilong Yuan; Shuai Ouyang; Zhi Fang; Shanhong Zhao; Tianyu Jia; Lifang Zou; Shouyu Wang; Yun Xue; Bing Wu; et al. (Purinergic Signalling, 2021)

Integrity investigation of global ionospheric TEC maps for high-precision positioning - Jiaojiao Zhao; Manuel Hernández-Pajares; Zishen Li; Ningbo Wang; Hong Yuan (Journal of Geodesy, 2021)
Aside from the ionospheric total electron content (TEC) information, root-mean-square (RMS) maps are also provided as the standard deviations of the corresponding TEC errors in global ionospheric maps (GIMs). As the RMS maps are commonly used as the accuracy indicator of GIMs to optimize the stochastic model of precise point positioning algorithms, it is of crucial importance to investigate the reliability of RMS maps involved in GIMs of different Ionospheric Associated Analysis Centers (IAACs) of the International GNSS Service (IGS), i.e., the integrity of GIMs. We indirectly analyzed the reliability of RMS maps by comparing the actual error of the differential STEC (dSTEC) with the RMS of the dSTEC derived from the RMS maps. With this method, the integrity of seven rapid IGS GIMs (UQRG, CORG, JPRG, WHRG, EHRG, EMRG, and IGRG) and six final GIMs (UPCG, CODG, JPLG, WHUG, ESAG and IGSG) was examined under the maximum and minimum solar activity conditions as well as the geomagnetic storm period. The results reveal that the reliability of the RMS maps is significantly different for the GIMs from different IAACs. Among these GIMs, the values in the RMS maps of UQRG are large, which can be used as ionospheric protection level, while the RMS values in EHRG and ESAG are significantly lower than the realistic RMS. The rapid and final GIMs from CODE, JPL and WHU provide quite reasonable RMS maps. The bounding performance of RMS maps can be influenced by the location of the stations, while the influence of solar activity and the geomagnetic storm is not obvious.

Efficient Editing of an Adenoviral Vector Genome with CRISPR/Cas9 - Qiang Li; Hui Wang; Chen-yu Gong; Zhao Chen; Jia-xing Yang; Hong-wei Shao; Wen-feng Zhang (Indian Journal of Microbiology, 2021)

Comprehensive upstream and downstream regulatory analyses identify miR-675-3p as a potential prognostic biomarker in melanoma - Cai-Chou Zhao; Hao Guo; Ying Wang; Jiu-Hong Li (Human Cell, 2021)
This study assessed miR-675-3p-related regulatory mechanisms in melanoma and the clinical relevance of such regulatory activities. We downloaded miRNA mature strand expression RNA-Seq, phenotypic, and DNA methylation data pertaining to the TCGA Melanoma cohort. Differentially expressed miRNAs (DEMs) between metastatic and primary melanoma patient tissues were then identified, and miR-675-3p expression in melanoma patient peripheral blood was confirmed using the GSE20994 GEO dataset, while its expression in melanoma cell lines was evaluated via qRT-RCR. The clinical and prognostic implications of miR-675-3p in melanoma were assessed, and miR-675-3p target genes were identified using bioinformatics tools. Functional roles of this miRNA were explored via Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. We identified 3 and 22 miRNAs that were up- and downregulated, respectively, in metastatic melanoma samples relative to primary melanoma samples. Upregulation of miR-675-3p was associated with poorer overall patient survival, tumor histologic grade, and Clark's level. Consistently, miR-675-3p was also overexpressed in the peripheral blood of melanoma patients relative to healthy controls, and in melanoma cell lines relative to control cells. Gene regulatory networks indicated that 32 transcription factors control miR-675-3p expression, and that it, in turn, regulates 10 target genes. KEGG analyses indicated that these genes were associated with cell cycle, transcriptional misregulation in cancer, TGF-beta signaling, and HIF-1 signaling pathways. Gain-of-function assays revealed that miR-675-3p could promote cell proliferation via accelerating cell cycle progression. Western blotting results indicated that miR-675-3p could active TGF-beta and HIF-1 signaling. Through upstream and downstream analyses of miR-675-3p-related regulatory activity, we confirmed that this miRNA participates in key melanoma-related processes and offers value as a prognostic biomarker in melanoma patients.

Maternal exposure to ambient SO2 and risk of polydactyly and syndactyly: a population-based case-control study in Liaoning Province, China - Yu-Ting Jiang; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; Qi-Jun Wu (Environmental Science and Pollution Research, 2021)

Expression of G9a in Auditory Cortex Is Downregulated in a Rat Model of Age-Related Hearing Loss - Qian Li; Yang-hong Xiang; Xiao-jun Liang; Yun Zhang; Peng-peng Zhao; Min Wang; Xiao-min Bao; Xian-bai Zhu; An-chun Deng (Journal of Molecular Neuroscience, 2021)

TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial–mesenchymal transition - Zhi-Han Li; Lei Lei; Liang-Ru Fei; Wen-Jing Huang; Yi-Wen Zheng; Mai-Qing Yang; Zhao Wang; Chen-Chen Liu; Hong-Tao Xu (Journal of Molecular Histology, 2021)

Research progress and hot spots of hydrothermal liquefaction for bio-oil production based on bibliometric analysis - Jian Yang; Chen Hong; Yi Xing; Zixuan Zheng; Zaixing Li; Xiumei Zhao; Chenhao Qi (Environmental Science and Pollution Research, 2021)

Retraction Note to: NPC-16, a novel naphthalimide–polyamine conjugate, induced apoptosis and autophagy in human hepatoma HepG2 cells and Bel-7402 cells - Song-qiang Xie; Qian Li; Ya-hong Zhang; Jian-hong Wang; Zi-hou Mei; Jin Zhao; Chao-jie Wang (Apoptosis, 2021)

IbERF71, with IbMYB340 and IbbHLH2, coregulates anthocyanin accumulation by binding to the IbANS1 promoter in purple-fleshed sweet potato (Ipomoea batatas L.) - Zhiyuan Ning; Kangdi Hu; Zhilin Zhou; Donglan Zhao; Jun Tang; Hong Wang; Lixia Li; Chen Ding; Xiaoyan Chen; Gaifang Yao; Hua Zhang (Plant Cell Reports, 2021)

Study on NOx removal from simulated flue gas by an electrobiofilm reactor: EDTA-ferrous regeneration and biological kinetics mechanism - Nan Liu; Ying-ying Li; Du-juan Ouyang; Rui Guo; Run Chen; Wei Li; Ji-xiang Li; Ji-hong Zhao (Environmental Science and Pollution Research, 2021)

The isolation of two new compounds from Valeriana jatamansi - Li-Qiu Quan; Qian Zhao; Rong-Tao Li; Hong-Mei Li (Natural Product Research, 2020)

A non-structural protein encoded by Rice Dwarf Virus targets to the nucleus and chloroplast and inhibits local RNA silencing - Feng Gao; Shanshan Zhao; Shuzhen Men; Zhensheng Kang; Jian Hong; Chunhong Wei; Wei Hong; Yi Li (Science China Life Sciences, 2020)

Mannheimia ovis sp. nov., Isolated from Dead Sheep with Hemorrhagic Pneumonia - Fuxiang Li; Wenhua Zhao; Jianbo Zhu; Qionghua Hong; Qingyong Shao; Shibiao Yang (Current Microbiology, 2020)

Leptin promotes endothelial dysfunction in chronic kidney disease by modulating the MTA1-mediated WNT/β-catenin pathway - Bing Liu; Jiao Qiao; Jinxiu Hu; Minghua Fan; Yanfang Zhao; Hong Su; Ziyang Wang; Qun Yu; Qiqi Ma; Yanmei Li; Zhimei Lv; Rong Wang (Molecular and Cellular Biochemistry, 2020)

LncRNA NFIA-AS2 promotes glioma progression through modulating the miR-655-3p/ZFX axis - Jun Xin; Yu-Hong Zhao; Xi-Yun Zhang; Li-Qiang Tian (Human Cell, 2020)

Comparison of mRNA Expression of P2X Receptor Subtypes in Different Arterial Tissues of Rats - Ling-Zhi Li; Li-Hui Yue; Zhi-Min Zhang; Jing Zhao; Lei-Ming Ren; Hong-Jie Wang; Lu Li (Biochemical Genetics, 2020)

OP16 induces deadly autophagy and apoptosis of cells by inhibiting Akt in esophageal squamous cell carcinoma - Guiqin Hou; Ang Jia; Li Yang; Yu Zhao; Yi Hu; Wuduo Zhao; Wen Zhao; Hong-Min Liu; Zhaoming Lu (Molecular and Cellular Biochemistry, 2020)

Retraction Note to: Ambient air pollution and adverse birth outcomes: a systematic review and meta-analysis - Le-qian Guo; Yu Chen; Bai-bing Mi; Shao-nong Dang; Dou-dou Zhao; Rong Liu; Hong-li Wang; Hong Yan (Journal of Zhejiang University-SCIENCE B, 2020)

Directional seismic response to the complex topography: A case study of 2013 Lushan Ms 7.0 earthquake - Bo Zhao; Yun-sheng Wang; Li-jun Su; Yong-hong Luo; Jing Zhang (Journal of Mountain Science, 2020)

Analysis of endophytic and rhizosphere bacterial diversity and function in the endangered plant Paeonia ludlowii - Yazhou Lu; Erhao Zhang; Mingsheng Hong; Xiu Yin; Hao Cai; Lei Yuan; Fang Yuan; Lianqiang Li; Kentian Zhao; Xiaozhong Lan (Archives of Microbiology, 2020)
Paeonia ludlowii is indigenous to Tibet and has an important ecological and economic value in China. In Tibet, P. ludlowii has been used in folk medicine with relative success. Plant microbial endophytes play an important role in plant growth, health and ecological function. The diversity of endophytic bacteria associated with P. ludlowii remains poorly understood. In this study, the structure of the endophytic bacterial communities associated with different tissues, including fruits, flowers, leaves, stems, and roots, and rhizosphere soils was analyzed with Illumina MiSeq sequencing of bacterial 16S rDNA. A total of 426,240 sequences and 4847 operational taxonomic units (OTUs) were obtained. The OTUs abundance of roots was higher than that of other tissues; however, the OTUs abundance was similar among different deep soil samples. In the plant tissues, Cyanobacteria was the most abundant bacterial phylum, followed by Proteobacteria; however, the most abundant phyla were Proteobacteria and Acidobacteria in soil samples from three different layers. In addition, the diversity and richness of the microorganisms in the soil were very similar to those in roots but higher than those in other tissues of P. ludlowii . Predictive metagenome analysis revealed that endophytic bacteria play critical functional roles in P. ludlowii . This conclusion could facilitate the study of the ecological functions of endophytic bacteria and their interactions with P. ludlowii to analyze the reasons why this important medicinal plant is becoming endangered.

Effective identification of CRISPR/Cas9-induced and naturally occurred mutations in rice using a multiplex ligation-dependent probe amplification-based method - Sukumar Biswas; Rong Li; Jun Hong; Xiangxiang Zhao; Zheng Yuan; Dabing Zhang; Jianxin Shi (Theoretical and Applied Genetics, 2020)

Effects of crop straw biochars on aluminum species in soil solution as related with the growth and yield of canola (Brassica napus L.) in an acidic Ultisol under field condition - Wen-rui Zhao; Jiu-yu Li; Kai-ying Deng; Ren-yong Shi; Jun Jiang; Zhi-neng Hong; Wei Qian; Xian He; Ren-kou Xu (Environmental Science and Pollution Research, 2020)

Pseudomonas Saliphila sp. nov., a Bacterium Isolated from Oil-Well Production Water in Qinghai Oilfield of China - Xiao-Juan Zhang; Hong-Can Liu; Yu-Guang Zhou; Xiao-Lei Wu; Yong Nie; Qi-Rui Li; Mei-Zhu Wang; Liang Zhao; Man Cai; Ying-Qian Kang (Current Microbiology, 2020)

Arsenic, lead, and cadmium bioaccessibility in contaminated soils: Measurements and validations - Hong-Bo Li; Meng-Ya Li; Di Zhao; Jie Li; Shi-Wei Li; Ping Xiang; Albert L. Juhasz; Lena Q. Ma (Critical Reviews in Environmental Science and Technology, 2020)

High-rate Doppler-aided cycle slip detection and repair method for low-cost single-frequency receivers - Jiaojiao Zhao; Manuel Hernández-Pajares; Zishen Li; Liang Wang; Hong Yuan (GPS Solutions, 2020)

Comparison of metabolites in juice, seed and peel of sea buckthorn (Hippophae rhamnoides L. subsp. sinensis) - Chuangyun Wang; Menglin Lei; Hong Zhang; Lijuan Zhao; Zhixin Mu; Meixia Wang; Jianhua Zhang; Yan Deng; Li Zhao (Journal of Plant Biochemistry and Biotechnology, 2020)

Epidemiological survey and genetic evolution of H3N2 subtype influenza viruses from stray dogs in Shanghai, China - Hai-Xiao Shen; Fei-Fei Ge; Xin Li; Jian Liu; Hou-Bing Ju; De-Quan Yang; Xian-Chao Yang; Jian Wang; Hong-Jin Zhao (Virus Genes, 2020)

Improved production of GTKO/hCD55/hCD59 triple-gene-modified Diannan miniature pigs for xenotransplantation by recloning - Heng Zhao; Yuying Li; Thanapa Wiriyahdamrong; Zaimei Yuan; Yubo Qing; Honghui Li; Kaixiang Xu; Jianxiong Guo; Baoyu Jia; Xuezeng Zhang; Wenmin Cheng; Yanhua Su; et al. (Transgenic Research, 2020)

Biological Aerosol Particles in Polluted Regions - Wei Hu; Zihan Wang; Shu Huang; Lujie Ren; Siyao Yue; Ping Li; Qiaorong Xie; Wanyu Zhao; Lianfang Wei; Hong Ren; Libin Wu; Junjun Deng; et al. (Current Pollution Reports, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

Identification of novel functional CpG-SNPs associated with type 2 diabetes and coronary artery disease - Zun Wang; Chuan Qiu; Xu Lin; Lan-Juan Zhao; Yong Liu; Xinrui Wu; Qian Wang; Wei Liu; Kelvin Li; Hong-Wen Deng; Si-Yuan Tang; Hui Shen (Molecular Genetics and Genomics, 2020)

Response of soil microbial communities to continuously mono-cropped cucumber under greenhouse conditions in a calcareous soil of north China - Yingnan Zhao; Xiaoxi Mao; Minshuo Zhang; Wei Yang; Hong J. Di; Li Ma; Wenju Liu; Bowen Li (Journal of Soils and Sediments, 2020)

Conversion between porcine naïve-like and primed ESCs and specific pluripotency marker identification - Qiaoyu Chen; Hong Zhang; Haibin Jiang; Manling Zhang; Junzheng Wang; Lihua Zhao; Chenyu Wang; Manling Liu; Rongfeng Li (In Vitro Cellular & Developmental Biology - Animal, 2020)

Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs. 3 doses in young women - Yue-Mei Hu; Meng Guo; Chang-Gui Li; Kai Chu; Wen-Gang He; Jing Zhang; Jian-Xiang Gu; Juan Li; Hui Zhao; Xiang-Hong Wu; BiZhen Lin; Zhi-Jie Lin; et al. (Science China Life Sciences, 2020)

The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line - Gen-Meng Yang; Lu Li; Feng-Lin Xue; Chen-Li Ma; Xiao-Feng Zeng; Yong-Na Zhao; Dong-Xian Zhang; Yang Yu; Qian-Wen Yan; Yi-Qing Zhou; Shi-Jun Hong; Li-Hua Li (Neurotoxicity Research, 2020)

Gypenosides Prevent H2O2-Induced Retinal Ganglion Cell Apoptosis by Concurrently Suppressing the Neuronal Oxidative Stress and Inflammatory Response - Hong-Kan Zhang; Yuan Ye; Kai-Jun Li; Zhen-ni Zhao; Jian-Feng He (Journal of Molecular Neuroscience, 2020)
Our previous study demonstrated that gypenosides (Gp) exert protective effects on retinal nerve fibers and axons in a mouse model of experimental autoimmune optic neuritis. However, the therapeutic mechanisms remain unclear. Thus, in this study, a model of oxidative damage in retinal ganglion cells (RGCs) was established to investigate the protective effect of Gp, and its possible influence on oxidative stress in RGCs. Treatment of cells with H 2 O 2 induced RGC injury owing to the generation of intracellular reactive oxygen species (ROS). In addition, the activities of antioxidative enzymes decreased and the expression of inflammatory factors increased, resulting in an increase in cellular apoptosis. Gp helped RGCs to become resistant to oxidation damage by directly reducing the amount of ROS in cells and exerting protective effects against H 2 O 2 -induced apoptosis. Treatment with Gp also reduced the generation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), and increased nuclear respiratory factor 2 (Nrf-2) levels so as to increase the levels of heme oxygenase-1 (HO-1) and glutathione peroxidase 1/2 (Gpx1/2), which can enhance antioxidation in RGCs. In conclusion, our data indicate that neuroprotection by Gp involves its antioxidation and anti-inflammation effects. Gp prevents apoptosis through a mitochondrial apoptotic pathway. This finding might provide novel insights into understanding the mechanism of the neuroprotective effects of gypenosides in the treatment of optic neuritis.

Litorilituus lipolyticus sp. nov., isolated from intertidal sand of the Yellow Sea in China, and emended description of Colwellia asteriadis - Ang Liu; Yan-Jiao Zhang; Qing-Jie Xue; Hui Wang; Yuan-Yuan Yang; Feng Du; Long-Yu Zhao; Hong-Hua Zhang; Yun-Qing Li; Xiu-Zhen Li (Antonie van Leeuwenhoek, 2020)

Effects of Dietary Supplementation of Recombinant Plectasin on Growth Performance, Intestinal Health and Innate Immunity Response in Broilers - Jing Lin Ma; Li Hua Zhao; Dan Dan Sun; Jing Zhang; Yong Peng Guo; Zhi Qiang Zhang; Qiu Gang Ma; Cheng Ji; Li Hong Zhao (Probiotics and Antimicrobial Proteins, 2020)

The false smut pathogen Ustilaginoidea virens requires rice stamens for false smut ball formation - Jing Fan; Jie Liu; Zhi‐You Gong; Pei‐Zhou Xu; Xiao‐Hong Hu; Jin‐Long Wu; Guo‐Bang Li; Juan Yang; Yu‐Qiu Wang; Yu‐Feng Zhou; Shuang‐Cheng Li; Li Wang; et al. (Environmental Microbiology, 2020)
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The disease is characterized by the transformation of individual rice florets into false smut balls, which is caused by the fungal pathogen Ustilaginoidea virens . To date, little is known about the host factors required for false smut ball formation by U . virens . In this study, we identified histological determinants for the formation of false smut balls by inoculating U . virens into rice floral mutants defective with respect to individual floral parts. The results showed that U . virens could form mature false smut balls in rice floral mutants with defective pistils, but failed to develop false smut balls in the superwoman mutant lacking stamens, identifying that U . virens requires rice stamens to complete its infection cycle. Comparative transcriptome analysis indicated a list of candidate host genes that may facilitate nutrient acquisition by U . virens from the rice stamens, such as SWEET11 , SWEET14 and SUT5 , and genes involved in the biosynthesis of trehalose and raffinose family sugars. These data pinpoint rice stamens as the key target organ of U . virens infection and provide a valuable starting point for dissecting the molecular mechanism of false smut ball formation.

Psychophysiological and cognitive effects of strawberry plants on people in isolated environments - Zhao-ming Li; Hui Liu; Wen-zhu Zhang; Hong Liu (Journal of Zhejiang University-SCIENCE B, 2020)

One bis-indole alkaloid-voacamine from Voacanga africana Stapf: biological activity evaluation of PTP1B in vitro utilizing enzymology method based on SPRi expriment - Yan-Qiu Wang; Hong-Xiang Li; Xiao-Chun Liu; Jin-Shuang Zhao; Rong-Qiang Liu; Wen-ying Huai; Wei-Jun Ding; Tian-E Zhang; Yun Deng (Natural Product Research, 2019)

Plant regeneration in Ixora chinensis from young leaves - TingGe Li; Hong Cai; TongXin Wang; YingGe Fu; WenHan Yang; AnJin Zhao; Zheng Cui; Jian Wang (Plant Cell, Tissue and Organ Culture (PCTOC), 2019)

The efflux pump inhibitor tetrandrine exhibits synergism with fluconazole or voriconazole against Candida parapsilosis - Ya-Jing Zhao; Wei-Da Liu; Yong-Nian Shen; Dong-Mei Li; Kun-Ju Zhu; Hong Zhang (Molecular Biology Reports, 2019)

Stress-dependent anisotropy index of strength and deformability of jointed rock mass: insights from a numerical study - Na Wu; Zheng-zhao Liang; Ying-chun Li; Hong Li; Wan-run Li; Mei-li Zhang (Bulletin of Engineering Geology and the Environment, 2019)

Genome-Wide Identification and Comparative Expression Profile Analysis of the Long-Chain Acyl-CoA synthetase (LACS) Gene Family in Two Different Oil Content Cultivars of Brassica napus - Zhongchun Xiao; Nannan Li; Shufeng Wang; Juanjuan Sun; Liyuan Zhang; Chao Zhang; Hong Yang; Huiyan Zhao; Bo Yang; Lijuan Wei; Hai Du; Cunmin Qu; et al. (Biochemical Genetics, 2019)

Effects of micrite microtextures on the elastic and petrophysical properties of carbonate reservoirs - Jian-Guo Pan; Ji-Xin Deng; Chuang Li; Hong-Bin Wang; Hu-Quan Zhang; Jian-Guo Zhao; Gen-Yang Tang (Applied Geophysics, 2019)