Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds - Minmin Qu; Hua Xu; Wuju Li; Jia Chen; Yajiao Zhang; Bin Xu; Zhi Li; Tao Liu; Lei Guo; Jianwei Xie (Archives of Toxicology, 2021)

A new ergostane derivative from the leaves of Heynea trijuga Roxburgh - Shou-Bai Liu; Zheng Cui; Hui-Qin Chen; Hao Wang; Wen-Hua Dong; Cai-Hong Cai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Two new isoquinoline alkaloids from the seeds of Nandina domestica - Juan Qin; Sheng-Yuan Zhang; Yu-Bo Zhang; Li-Feng Chen; Neng-Hua Chen; Zhong-Nan Wu; Ding Luo; Guo-Cai Wang; Yao-Lan Li (Natural Product Research, 2021)

Seasonal progression of photoprotection responses in different aged savin juniper plants under shade and sun - Jin-Ling Zhang; Xiao-Gang Li; Xue-Hua Xu; Hai-Peng Chen; Yu-Ling Li; Robert D. Guy (Trees, 2021)

Identification of RNA helicases in Medicago truncatula and their expression patterns under abiotic stress - Jie Cheng; Songsong Zhou; Kun Yang; Hongyang Yu; Rongrong Chen; Liming Zeng; Hua Li; Yihua Wang; Jianbo Song (Physiology and Molecular Biology of Plants, 2021)

Downregulation of fibronectin 1 attenuates ATRA-induced inhibition of cell migration and invasion in neuroblastoma cells - Xiaolin Tan; Wei Gong; Bo Chen; Baocheng Gong; Zhongyan Hua; Simeng Zhang; Yang Chen; Qi Li; Zhijie Li (Molecular and Cellular Biochemistry, 2021)

An Investigation of Toxic Metal Levels (Pb, Cd, Cr, As, Hg) in Dried Porphyra and Laminaria Collected from Coastal Cities, China - Yan Chen; Yong-tao Liu; Fu-hua Wang; Dian Wen; Hui Yang; Xiao-li Zhao (Biological Trace Element Research, 2021)

Sandaracinobacteroides hominis gen. nov., sp. nov., isolated from human skin - Ping-Hua Qu; Hai-Min Luo; Jun-Hui Feng; Song Li; Cha Chen; Lei Dong; Yu-Zhen Ming; Wen-Jun Li; Ying Lin (Archives of Microbiology, 2021)

Influence of elevation on bioregionalisation: A case study of the Sino‐Himalayan flora - Yun Liu; Jian‐Fei Ye; Hai‐Hua Hu; Dan‐Xiao Peng; Li‐Na Zhao; Li‐Min Lu; Wajid Zaman; Zhi‐Duan Chen (Journal of Biogeography, 2021)
Aim Elevation is an important factor that influences bioregionalisation in mountainous areas, but its effects are not well known. Taking the Sino‐Himalayan flora as a case, we aimed to test the effect of elevation on bioregionalisation and provide a regionalisation scheme of the Sino‐Himalayan flora. Location The Sino‐Himalaya (East Himalaya, the Hengduan Mountains and the Yunnan Plateau in China). Taxon Angiosperms. Methods We compiled distribution data and elevation ranges of angiosperms in the Sino‐Himalaya and adjacent areas and reconstructed a species‐level phylogenetic tree of 19,313 angiosperm species. The area was divided into 398 grid cells, each 1 × 1°. Nine datasets of different elevation ranges were then used to delineate the flora of the Sino‐Himalaya and adjacent areas using the phylogenetic dissimilarity approach. Results A comparison of nine regionalisation schemes of the Sino‐Himalayan flora based on different elevation range datasets revealed that more than half of grid cells were allocated to more than one subregion. Most of these grid cells were located in areas with a wide range of elevation and/or at the boundaries between subregions. After revising the subregion allocations of eight shifting grid cells, we generated a phylogeny‐ and elevation‐based regionalisation scheme of three regions, comprising eight subregions, for the Sino‐Himalayan flora. Main conclusions By integrating phylogenetic and elevational information, the Sino‐Himalaya can be divided into three floristic regions: the Yunnan Plateau region, the Hengduan Mountains region and the East Himalaya region. Our study provides novel insights into the regionalisation of the flora and highlights the importance of incorporating elevation data in the bioregionalisation of areas with a broad elevational range.

On the origin of SARS-CoV-2—The blind watchmaker argument - Chung-I Wu; Haijun Wen; Jian Lu; Xiao-dong Su; Alice C. Hughes; Weiwei Zhai; Chen Chen; Hua Chen; Mingkun Li; Shuhui Song; Zhaohui Qian; Qihui Wang; et al. (Science China Life Sciences, 2021)

A Frameshift Variant in the SEMA6B Gene Causes Global Developmental Delay and Febrile Seizures - Li Shu; Yuchen Xu; Qi Tian; Yuanyuan Chen; Yaqin Wang; Hui Xi; Hua Wang; Neng Xiao; Xiao Mao (Neuroscience Bulletin, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Enhancing oil recovery through immiscible water-alternating-CO2 in tight oil formations—a case study of Yaoyingtai Field in China - Hua Liu; Lin Chen; Xiangfang Li; Hongya Wang; Zheng Sun (Arabian Journal of Geosciences, 2021)

What induces the interdecadal shift of the dipole patterns of summer precipitation trends over the Tibetan Plateau? - Yong Liu; Huopo Chen; Hua Li; Guoqing Zhang; Huijun Wang (International Journal of Climatology, 2021)
Precipitation on the Tibetan Plateau (TP) exert great impacts on the energy, water cycle, and regional ecosystem. But due to the wide differences in climate regimes and complicated topography, TP precipitation is characterized as greater spatial diversity and lower confidence of temporal tendency. Based on the precipitation datasets from in situ observations, reanalysis, and satellites, this study identifies the interdecadal shift of the summer precipitation trends in the southern and northern TP, which corresponds well with the remarkable changes of TP lakes area in recent years. The statistical results indicate that the TP summer precipitation has experienced an interdecadal transition in the late 1990s, with precipitation increasing and then decreasing in the southern TP, and decreasing and then increasing in the northern TP. Further analyses suggest that the changes in moisture budget and convection activities play an important role in the interdecadal variations of precipitation in the northern and southern TP, respectively. More specifically, the variations in the southern TP are contributed largely by the persistent weakening sensible heat source, which can depress the ascending motion and hinder the northward moisture transport in the southern TP. While in the northern TP, both observations and model sensitivity experiments indicate that the co‐effect of the cold interdecadal Pacific oscillation (IPO) and warm Atlantic multidecadal oscillation (AMO) has profound impacts on the decadal shift of the net moisture budget in the northern TP. Specifically, the AMO can impact the Lake Baikal anticyclone through the anomalous wave propagation and then decrease the moisture output in the eastern TP. While the IPO can weaken the climatological westerlies and prompt the moisture to get stuck in the northern TP. Consequently, the variations in the net moisture budget can give rise to the decadal variations in summer precipitation in the northern TP.

Corticosterone Can Be an Essential Stress Index in Channel Catfish (Ictalurus punctatus) - Kang Xiao; Xi Wang; Wen-Bin Liu; Ding-Dong Zhang; Xiang-Fei Li; Chun-Nuan Zhang; Wei-Hua Chen; Kenneth Prudence Abasubong; Guang-Zhen Jiang (Frontiers in Marine Science, 2021)
Although cortisol is considered the main glucocorticoid involved in regulating stress in fish by elevating the serum glucose, the presence of serum corticosterone and whether its level can be used as an indicator for fish stress activation and reflect the degree of fish stress remains to be determined. To comprehensively and accurately evaluate the performance of two glucocorticoids after stress, in this study, seven of the most common stressors (ammonia nitrogen, high-temperature, acid, alkali, Aeromonas hydrophila, and salinity) in aquaculture were selected. The levels of serum corticosterone, cortisol, and glucose were detected within 48 h, and then the dynamic changes were analyzed. In addition, the kidneys were collected to detect the expression of corresponding proteins involved in corticosterone and cortisol synthesis (3 β-HSD and CYP17A1) for further exploration. From the results obtained, the content of serum corticosterone was about 100 times higher than that of cortisol, and it was found that corticosterone and cortisol showed different dynamic changes within 48 h among the seven kinds of stress. In the subsequent detection of glucose, it was found that the dynamic shift in glucose was not consistent with the dynamic changes of corticosterone or cortisol entirely but seemed to be caused by the combination of the two. In the follow-up protein expression detection, we found that corticosterone seemed to respond to stress earlier. Therefore, it is concluded that the responses of corticosterone and cortisol to stress are independent, corticosterone may be more sensitive in the current seven acute stresses, and then they regulate glucose together to resist stress. The study aimed to fill the vacancy of corticosterone in fish research and provide a reference for the complete evaluation of fish stress degree.

The Amygdala Responds Rapidly to Flashes Linked to Direct Retinal Innervation: A Flash-evoked Potential Study Across Cortical and Subcortical Visual Pathways - Yanmei Chen; Yiling Ni; Jianhong Zhou; Hua Zhou; Qian Zhong; Xinyue Li; Jichuan Zhang; Yuanye Ma; Jingkuan Wei (Neuroscience Bulletin, 2021)

Maternal exposure to sulfur dioxide and the risk of oral clefts in Liaoning Province, China: a population-based case-control study - Fang-Hua Liu; Ze Xing; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; et al. (Environmental Science and Pollution Research, 2021)

Biochar co-application mitigated the stimulation of organic amendments on soil respiration by decreasing microbial activities in an infertile soil - Qifeng Wu; Ruiyuan Lian; Meixia Bai; Jianping Bao; Yang Liu; Songhao Li; Chenfei Liang; Hua Qin; Junhui Chen; Qiufang Xu (Biology and Fertility of Soils, 2021)

Phase field model for hydraulic fracture propagation in porous medium and numerical simulation analysis of hydraulic fracture propagation in a layered reservoir - Liang-Ping Yi; Chang-Xin Yang; Rui Chen; Jing-Yi Zhu; Xiao-Hua Zhu; Zhao-Zhong Yang; Xiao-Gang Li (Arabian Journal of Geosciences, 2021)

Three new 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones and one new dimeric 2-(2-phenylethyl)chromone from agarwood of Aquilaria crassna Pierre ex Lecomte in Laos - Yang-Mei Zhao; Li Yang; Fan-Dong Kong; Wen-Hua Dong; Wei Li; Hui-Qin Chen; Hao Wang; Cai-Hong Cai; Cui-Juan Gai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Stripe rust resistance gene Yr34 (synonym Yr48) is located within a distal translocation of Triticum monococcum chromosome 5AmL into common wheat - Shisheng Chen; Joshua Hegarty; Tao Shen; Lei Hua; Hongna Li; Jing Luo; Hongyu Li; Shengsheng Bai; Chaozhong Zhang; Jorge Dubcovsky (Theoretical and Applied Genetics, 2021)
Key message The stripe rust resistance gene Yr34 was transferred to polyploid wheat chromosome 5AL from T. monococcum and has been used for over two centuries. Wheat stripe (or yellow) rust, caused by Puccinia striiformis f. sp. tritici ( Pst ), is currently among the most damaging fungal diseases of wheat worldwide. In this study, we report that the stripe rust resistance gene Yr34 (synonym Yr48 ) is located within a distal segment of the cultivated Triticum monococcum subsp. monococcum chromosome 5A m L translocated to chromosome 5AL in polyploid wheat. The diploid wheat species Triticum monococcum (genome A m A m ) is closely related to T . urartu (donor of the A genome to polyploid wheat) and has good levels of resistance against the stripe rust pathogen. When present in hexaploid wheat, the T. monococcum Yr34 resistance gene confers a moderate level of resistance against virulent Pst races present in California and the virulent Chinese race CYR34. In a survey of 1,442 common wheat genotypes, we identified 5A m L translocations of fourteen different lengths in 17.5% of the accessions, with higher frequencies in Europe than in other continents. The old European wheat variety “Mediterranean” was identified as a putative source of this translocation, suggesting that Yr34 has been used for over 200 years. Finally, we designed diagnostic CAPS and sequenced-based markers that will be useful to accelerate the deployment of Yr34 in wheat breeding programs to improve resistance to this devastating pathogen.

Layers of interstitial fluid flow along a “slit-shaped” vascular adventitia - Hongyi Li; You Lyu; Xiaoliang Chen; Bei Li; Qi Hua; Fusui Ji; Yajun Yin; Hua Li (Journal of Zhejiang University-SCIENCE B, 2021)

An effective interpolation strategy for mitigating the day boundary discontinuities of precise GNSS orbit products - Chuanfeng Song; Hua Chen; Weiping Jiang; Xiangdong An; Qusen Chen; Wudong Li (GPS Solutions, 2021)

Cysteiniphilum marinum sp. nov., isolated from coastal seawater - Hai-Min Luo; Jun-Hui Feng; Liang-Hui Li; Meng-Meng Li; Ru-Qin Liu; Fu Chen; Ying Lin; Wen-Jun Li; Ping-Hua Qu; Min Xiao (Antonie van Leeuwenhoek, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Correction to: Development of Apremilast Solid Dispersion Using TPGS and PVPVA with Enhanced Solubility and Bioavailability - Liuhong Yang; Penghui Wu; Jinchao Xu; Dihuan Xie; Zhongqing Wang; Qian Wang; Yong Chen; Chuan Hua Li; Jiaxin Zhang; Hangping Chen; Guilan Quan (AAPS PharmSciTech, 2021)

Analyzing 13 Years of Cetacean Strandings: Multiple Stressors to Cetaceans in Taiwanese Waters and Their Implications for Conservation and Future Research - Wen-Ta Li; Lien-Siang Chou; Hue-Ying Chiou; I-Hua Chen; Wei-Cheng Yang (Frontiers in Marine Science, 2021)
This study summarizes the postmortem investigations of 73 cetaceans stranded on the coast of Taiwan between 2001 and 2013, including 51 Delphinidae, 17 Kogiidae, 3 Ziphiidae, 1 Physeteridae, and 1 Balaenopteridae. Of these, eight (11%) were categorized into direct human-related strandings, including fisheries interaction (bycatch), vessel collision and other anthropogenic-related pathology. Gastrointestinal foreign bodies were found in eight individuals (11%). Most of the bacteria isolated from stranded dolphins were zoonotic pathogens including extended-spectrum β-lactamases Escherichia coli , which indicates waste pollution from land. Severe parasite infestation was found in 36 of the cases (49%), which suggests that the immune function could be compromised. Thirty-eight cases (52%) were diagnosed with myocardial patchy fibrosis or dilated cardiomyopathy. The evidence shown here indicates that cetaceans around Taiwanese waters may suffer from multiple stressors. This study provides baseline data for the health assessment of cetacean populations in Taiwan, which may ultimately provide recommendations for future cetacean conservation and research throughout the western Pacific.

Analysis of unigenes involved in lateral root development in Bupleurum chinense and B. scorzonerifolium - Ma Yu; Hua Chen; Qian Liu; Jing Huang; Kassa Semagn; Dan Liu; Yuchan Li; Bin Yang; Yilian He; Chun Sui; Dabin Hou; Jianhe Wei (Planta, 2021)

Genome-Wide Identification and Expression Analysis of Heavy Metal Stress–Responsive Metallothionein Family Genes in Nicotiana tabacum - Qin Yu; Linshen He; Chunsong Huo; Xiaohan Jiang; Hua Chen; Run Wang; Minzhi Tang; Ling Dong; Ji Chen; Yonghao Li; Shunqin Zhu; Wanhong Liu (Plant Molecular Biology Reporter, 2021)

Somatic embryogenesis of masson pine (Pinus massoniana): initiation, maturation and genetic stability analysis at SSR loci - Xin-Rui Xia; Fan Yang; Xin Ke; You-Mei Chen; Jian-Ren Ye; Li-Hua Zhu (Plant Cell, Tissue and Organ Culture (PCTOC), 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment - Rui-Yuan Zhang; Jie-Bai Tu; Rui-Tu Ran; Wen-Xuan Zhang; Qiang Tan; Ping Tang; Tao Kuang; Shu-Qun Cheng; Cheng-Zhi Chen; Xue-Jun Jiang; Chang Chen; Ting-Li Han; et al. (Neurotoxicity Research, 2021)

RNA-Seq Transcriptome Analysis of the Liver and Brain of the Black Carp (Mylopharyngodon piceus) During Fasting - Ya-Fan Dai; Yu-bang Shen; Shen-Tong Wang; Jia-Hua Zhang; Yu-Hong Su; Sheng-Chen Bao; Xiao-Yan Xu; Jia-Le Li (Marine Biotechnology, 2021)

Soil fertility, enzyme activity, and microbial community structure diversity among different soil textures under different land use types in coastal saline soil - Yun Zhu; Bin Guo; Chen Liu; Yicheng Lin; Qinglin Fu; Ningyu Li; Hua Li (Journal of Soils and Sediments, 2021)

Differences in immunity between pathogen-resistant and -susceptible yam cultivars reveal insights into disease prevention underlying ethylene supplementation - Shumei Hua; Zhihua Chen; Lihong Li; Kuan-Hung Lin; Yangwen Zhang; Jieyu Yang; Shi-Peng Chen (Journal of Plant Biochemistry and Biotechnology, 2021)

Seasonal variation of nitrogen biogeochemical processes constrained by nitrate dual isotopes in cascade reservoirs, Southwestern China - Sai-Nan Chen; Fu-Jun Yue; Xiao-Long Liu; Jun Zhong; Yuan-Bi Yi; Wan-Fa Wang; Yulin Qi; Hua-Yun Xiao; Si-Liang Li (Environmental Science and Pollution Research, 2021)

Disrupted pathways from frontal-parietal cortex to basal ganglia and cerebellum in patients with unmedicated obsessive compulsive disorder as observed by whole-brain resting-state effective connectivity analysis – a small sample pilot study - Wei Liu; Minghui Hua; Jun Qin; Qiuju Tang; Yunyi Han; Hongjun Tian; Daxiang Lian; Zhengqing Zhang; Wenqiang Wang; Chunxiang Wang; Ce Chen; Deguo Jiang; et al. (Brain Imaging and Behavior, 2021)

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

Erratum to: Spatio-temporal variation of Fraction of Photosynthetically Active Radiation absorbed by vegetation in the Hengduan Mountains, China - Zheng-lan Yang; Ting-bin Zhang; Gui-hua Yi; Jing-ji Li; Yan-bin Qin; Yang Chen (Journal of Mountain Science, 2021)

Ground roll separation method via threshold filtering and constraint of seismic wavelet support in curvelet domain - De-ying Wang; Li-hua Chen; Lie-qian Dong; Li-hong Zhao; Ren-wei Ding; Cheng-zhen Ding (Applied Geophysics, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Multiple diversity facets of crucial microbial groups in biological soil crusts promote soil multifunctionality - Hua Li; Youxin Chen; Gongliang Yu; Federico Rossi; Da Huo; Roberto De Philippis; Xiaoli Cheng; Weibo Wang; Renhui Li (Global Ecology and Biogeography, 2021)
Aim Microbial diversity is one of the most important factors for maintaining the performance of multiple functions in soils (multifunctionality). However, existing studies typically consider the taxonomic richness or Shannon diversity of the entire community. We know little about the connection network of taxonomic and phylogenetic facets of diversity and their collective impact on multifunctionality. In this study, the linkages of effects of diversity within functional groups were disentangled in drylands. Location The central Tibetan Plateau. Time period Present. Major taxa studied Phototrophs and diazotrophs (mainly cyanobacteria). Methods Given the carbon‐ and nitrogen‐limited nature of drylands, we conducted a high‐throughput sequencing of C/N‐fixing functional groups from biocrusts and evaluated multiple facets of diversity (i.e., richness, evenness and phylogeny‐related trait dissimilarity), together with seven crucial variables of soil functioning to calculate multifunctionality. The relationships between multifaceted diversity and abundance with individual functions and multifunctionality were validated by a set of solid statistical analyses. Results We found that the integrated biodiversity index was a stronger predictor of multifunctionality than richness. The divergent performance of different facets of diversity determined the idiosyncratic effect of each functional group on soil multifunctionality. Moreover, the evaluation of functional significance at the species level gave important clues on the trade‐offs and redundancy in each functional group, explaining the distinct patterns of effects of diversity. Richness was the dominant factor for diazotrophs to maximize multifunctionality, whereas phylogenetic dissimilarity was the essential one for phototrophs. Main conclusions Our study demonstrated that multiple facets of diversity should be considered when assessing the effects of biodiversity. In contrast to the community level, within‐functional group measures might adequately capture the features of diversity that are most correlated with soil multifunctionality. Our results provide a perspective to bridge the gap between taxonomic and trait‐based approaches for elucidating the biodiversity–ecosystem function relationship.

Diversity, metabolism and cultivation of archaea in mangrove ecosystems - Cui-Jing Zhang; Yu-Lian Chen; Yi-Hua Sun; Jie Pan; Ming-Wei Cai; Meng Li (Marine Life Science & Technology, 2021)

Establishment and characterization of 38 novel patient-derived primary cancer cell lines using multi-region sampling revealing intra-tumor heterogeneity of gallbladder carcinoma - Feiling Feng; Qingbao Cheng; Bin Li; Chen Liu; Huizhen Wang; Bin Li; Xiaoya Xu; Yong Yu; Zishuo Chen; Xiaobing Wu; Hua Dong; Kaijian Chu; et al. (Human Cell, 2021)
Gallbladder carcinoma (GBC) is a lethal biliary tract malignant neoplasm. Patient-derived primary cancer cell lines (PDPCs) are appropriate models to explore biological characteristics and potential therapeutics; however, there is a lack of PDPCs in GBC. In this study, we aimed to establish and characterize the GBC PDPCs, and further investigated the intra-tumor heterogeneity (ITH). Multi-region sampling (3–9 regions) of the operable tumor tissue samples was used to establish PDPCs. Short tandem repeat genotyping for cell authentication and karyotyping was performed, followed by whole-exome sequencing and RNA sequencing to assess the ITH at the genetic and transcriptional levels, respectively. Thirty-eight PDPCs were successfully established from seven GBC patients and characterized. ITH was observed with a median of 38.3% mutations being heterogeneous (range, 26.6–59.4%) across all patients. Similar with other tumor types, TP53 mutations were always truncal. In addition, there were three genes, KMT2C , CDKN2A , and ARID1A , with truncal mutations in at least two patients. A median of 370 differentially expressed genes (DEGs) was identified per patient. Distinct expression patterns were observed between major histocompatibility complex (MHC) class I and II genes. We found the expression of MHC class II genes in the PDPC samples was closely regulated by CIITA , while that of MHC class I genes were not correlated with CIITA expression. The PDPCs established from GBC patients can serve as novel in vitro models to identify the ITH, which may pave a crucial molecular foundation for enhanced understanding of tumorigenesis and progression.

Electrochemical performance and response of bacterial community during phenanthrene degradation in single-chamber air-cathode microbial fuel cells - Tao Hua; Haonan Wang; Shengnan Li; Peng Chen; Fengxiang Li; Wei Wang (Environmental Science and Pollution Research, 2021)

ZnO nanorods/Fe3O4-graphene oxide/metal-organic framework nanocomposite: recyclable and robust photocatalyst for degradation of pharmaceutical pollutants - Li Chen; Jun Peng; Fangqi Wang; Donghao Liu; Wenrong Ma; Jinmeng Zhang; Wenqing Hu; Ning Li; Pierre Dramou; Hua He (Environmental Science and Pollution Research, 2021)

Di-(2-ethylhexyl) phthalate induces testicular endoplasmic reticulum stress and germ cell apoptosis in adolescent mice - Bin-Bin Zhu; Zhi-Cheng Zhang; Jian Li; Xing-Xing Gao; Yuan-Hua Chen; Hua Wang; Lan Gao; De-Xiang Xu (Environmental Science and Pollution Research, 2021)

Impacts of land use change on thermodynamic and dynamic changes of precipitation for the Yangtze River Basin, China - Qian Lin; Jie Chen; Wei Li; Kailin Huang; Xuezhi Tan; Hua Chen (International Journal of Climatology, 2021)
Many studies found that land use change (LUC) had great impacts on regional precipitation, due to thermodynamic and dynamic responses. However, the relative contributions of these two factors to changes in precipitation due to LUC are rarely investigated. This study quantifies the relative contributions of thermodynamic and dynamic to the changes of mean and extreme precipitation due to LUC based on simulations of the Weather Research and Forecasting (WRF) model. The Yangtze River Basin (YRB) is used as a case study, as it has experienced great LUC during the past decades. Four land use scenarios (two factual cases and two hypothetical reforestation scenarios) were used to test the sensitivity of precipitation changes to LUC. Changes in mean and extreme precipitation over the YRB for all seasons are attributed to thermodynamic and dynamic changes using 500‐hPa geopotential height and precipitation data derived from the simulations of WRF. The results show that the factual process of LUC results in a decrease in summer mean daily precipitation and precipitation extremes in most areas of the YRB (except for the middle reaches of the YRB), while the hypothetical reforestation contributes to an increase in summer mean and extreme precipitation, and the impacts of reforestation on increasing precipitation are limited. The thermodynamic change contributes to an increase in seasonal mean daily precipitation, extreme precipitation totals and occurrence frequency of precipitation extremes with contributions ranging from 94 to 102%, which is the main contributor of changes in precipitation due to LUC. The dynamic change only makes a small contribution to the change of precipitation. Because the contributions of thermodynamic can be offset by dynamic changes to changes in precipitation, it could result in minimal changes in precipitation and occurrences of precipitation extremes.

Development of Apremilast Solid Dispersion Using TPGS and PVPVA with Enhanced Solubility and Bioavailability - Liuhong Yang; Penghui Wu; Jinchao Xu; Dihuan Xie; Zhongqing Wang; Qian Wang; Yong Chen; Chuan Hua Li; Jiaxin Zhang; Hangping Chen; Guilan Quan (AAPS PharmSciTech, 2021)

Evaluation of the efficacy and safety of hydroxychloroquine in comparison with chloroquine in moderate and severe patients with COVID-19 - Qiuyu Li; Cheng Cui; Fei Xu; Jianping Zhao; Nan Li; Haichao Li; Tianbing Wang; Hua Zhang; Na Liu; Yudong Wei; Xiaoye Niu; Yan Xu; et al. (Science China Life Sciences, 2021)

The Roles of Epinephelus coioides miR-122 in SGIV Infection and Replication - Hong-Yan Sun; Yu-Ling Su; Pin-Hong Li; Jia-Yang He; He-Jia Chen; Gang Wang; Shao-Wen Wang; Xiao-Hong Huang; You-Hua Huang; Qi-Wei Qin (Marine Biotechnology, 2021)
In mammals, mature miR-122 is 22 nucleotides long and can be involved in regulating a variety of physiological and biological pathways. In this study, the expression profile and effects of grouper Epinephelus coioides miR-122 response to Singapore grouper iridovirus (SGIV) infection were investigated. The sequences of mature microRNAs (miRNAs) from different organisms are highly conserved, and miR-122 from E. coioides exhibits high similarity to that from mammals and other fish. The expression of miR-122 was up-regulated during SGIV infection. Up-regulation of miR-122 could significantly enhance the cytopathic effects (CPE) induced by SGIV, the transcription levels of viral genes (MCP, VP19, LITAF and ICP18), and viral replication; reduce the expression of inflammatory factors (TNF-a, IL-6, and IL-8), and the activity of AP-1 and NF-κB, and miR-122 can bind the target gene p38α MAPK to regulate the SGIV-induced cell apoptosis and the protease activity of caspase-3. The results indicated that SGIV infection can up-regulate the expression of E. coioides miR-122, and up-regulation of miR-122 can affect the activation of inflammatory factors, the activity of AP-1 and NF-κB, and cell apoptosis to regulate viral replication and proliferation.

Spatio-temporal variation of Fraction of Photosynthetically Active Radiation absorbed by vegetation in the Hengduan Mountains, China - Zheng-Ian Yang; Ting-bin Zhang; Gui-hua Yi; Jing-ji Li; Yan-bin Qin; Yang Chen (Journal of Mountain Science, 2021)

Simultaneous detection of multiple bacterial and viral aquatic pathogens using a fluorogenic loop‐mediated isothermal amplification‐based dual‐sample microfluidic chip - Qian‐Jin Zhou; Jian‐Fei Lu; Xiu‐Rong Su; Jing‐Lei Jin; Shang‐Yang Li; Yan Zhou; Lei Wang; Xin‐Bin Shao; Yao‐Hua Wang; Mao‐Cang Yan; Ming‐Yun Li; Jiong Chen (Journal of Fish Diseases, 2021)
Rapid and user‐friendly diagnostic tests are necessary for early diagnosis and immediate detection of diseases, particularly for on‐site screening of pathogenic microorganisms in aquaculture. In this study, we developed a dual‐sample microfluidic chip integrated with a real‐time fluorogenic loop‐mediated isothermal amplification assay (dual‐sample on‐chip LAMP) to simultaneously detect 10 pathogenic microorganisms, that is Aeromonas hydrophila , Edwardsiella tarda , Vibrio harveyi , V. alginolyticus , V. anguillarum , V. parahaemolyticus , V. vulnificus , infectious hypodermal and haematopoietic necrosis virus, infectious spleen and kidney necrosis virus, and white spot syndrome virus. This on‐chip LAMP provided a nearly automated protocol that can analyse two samples simultaneously, and the tests achieved limits of detection (LOD) ranging from 10 0 to 10 –1 pg/μl for genomic DNA of tested bacteria and 10 –4 to 10 –5 pg/μl for recombinant plasmid DNA of tested viruses, with run times averaging less than 30 min. The coefficient of variation for the time‐to‐positive value was less than 10%, reflecting a robust reproducibility. The clinical sensitivity and specificity were 93.52% and 85.53%, respectively, compared to conventional microbiological or clinical methods. The on‐chip LAMP assay provides an effective dual‐sample and multiple pathogen analysis, and thus would be applicable to on‐site detection and routine monitoring of multiple pathogens in aquaculture.

Cortical Hemodynamic Response Associated with Spatial Coding: A Near-Infrared Spectroscopy Study - Abiot Y. Derbie; Bolton Chau; Bess Lam; Yun-hua Fang; Kin-Hung Ting; Clive Y. H. Wong; Jing Tao; Li-dian Chen; Chetwyn C. H. Chan (Brain Topography, 2021)

Soil amendment in plastic greenhouse using modified biochar: soil bacterial diversity responses and microbial biomass carbon and nitrogen - Bin Hua; Zhouwen Li; Weikai Gao; Huilin Feng; Nan Chen; Jiayi Li; Xiaoming Ji; Lu Zhang; Zhiyong Wu; Shen Yan; Tianbao Ren; Chensheng Xu; et al. (Biotechnology Letters, 2021)

Arbuscular mycorrhizal colonization rate of an exotic plant, Galinsoga quadriradiata, in mountain ranges changes with altitude - Gang Liu; Rui-Ling Liu; Wen-Gang Zhang; Ying-Bo Yang; Xiao-Qiong Bi; Ming-Zhu Li; Xiao-Yan Chen; Hua Nie; Zhi-Hong Zhu (Mycorrhiza, 2021)

Adsorption Separation of CO2/CH4 from Landfill Gas by Ethanolamine-Modified Silica Gel - Yong Zhang; Kejin Chen; Chao Lv; Taijun Wu; Yonglin Wen; Hua He; Sheng Yu; Li’ao Wang (Water, Air, & Soil Pollution, 2021)

The MYB transcription factor Baymax1 plays a critical role in rice male fertility - Xiao-Jiao Xiang; Lian-Ping Sun; Ping Yu; Zheng-Fu Yang; Pei-Pei Zhang; Ying-Xin Zhang; Wei-Xun Wu; Dai-Bo Chen; Xiao-Deng Zhan; Riaz-Muhammad Khan; Adil Abbas; Shi-Hua Cheng; et al. (Theoretical and Applied Genetics, 2021)

Ferroptosis occurs in phase of reperfusion but not ischemia in rat heart following ischemia or ischemia/reperfusion - Li-Jing Tang; Xiu-Ju Luo; Hua Tu; Heng Chen; Xiao-Ming Xiong; Nian-Sheng Li; Jun Peng (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Deep Placement of Nitrogen Fertilizer Affects Grain Yield, Nitrogen Recovery Efficiency, and Root Characteristics in Direct-Seeded Rice in South China - Yunyan Chen; Pingshan Fan; Zhaowen Mo; Leilei Kong; Hua Tian; Meiyang Duan; Lin Li; Liji Wu; Zaimang Wang; Xiangru Tang; Shenggang Pan (Journal of Plant Growth Regulation, 2021)

Genetic and epigenetic variations in barley (Hordeum vulgare L.) using SSR and MSAP approaches - Bo Li; Qiang Gong; Wei Hua; Gonghai Chen; Wenying Zhang; Yanhao Xu; Chengdao Li (Genetic Resources and Crop Evolution, 2021)

Study on Rock Burst Prediction of Deep Buried Tunnel Based on Cusp Catastrophe Theory - Chen Qiao; Yan-hua Guo; Chang-hong Li (Geotechnical and Geological Engineering, 2021)

The CMIP6 Historical Simulation Datasets Produced by the Climate System Model CAMS-CSM - Xinyao Rong; Jian Li; Haoming Chen; Jingzhi Su; Lijuan Hua; Zhengqiu Zhang; Yufei Xin (Advances in Atmospheric Sciences, 2021)
This paper describes the historical simulations produced by the Chinese Academy of Meteorological Sciences (CAMS) climate system model (CAMS-CSM), which are contributing to phase 6 of the Coupled Model Intercomparison Project (CMIP6). The model description, experiment design and model outputs are presented. Three members’ historical experiments are conducted by CAMS-CSM, with two members starting from different initial conditions, and one excluding the stratospheric aerosol to identify the effect of volcanic eruptions. The outputs of the historical experiments are also validated using observational data. It is found that the model can reproduce the climatological mean states and seasonal cycle of the major climate system quantities, including the surface air temperature, precipitation, and the equatorial thermocline. The long-term trend of air temperature and precipitation is also reasonably captured by CAMS-CSM. There are still some biases in the model that need further improvement. This paper can help the users to better understand the performance and the datasets of CAMS-CSM.

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

IbERF71, with IbMYB340 and IbbHLH2, coregulates anthocyanin accumulation by binding to the IbANS1 promoter in purple-fleshed sweet potato (Ipomoea batatas L.) - Zhiyuan Ning; Kangdi Hu; Zhilin Zhou; Donglan Zhao; Jun Tang; Hong Wang; Lixia Li; Chen Ding; Xiaoyan Chen; Gaifang Yao; Hua Zhang (Plant Cell Reports, 2021)

Characterization of the complete mitochondrial genome of Macrotocinclus affinis (Siluriformes; Loricariidae) and phylogenetic studies of Siluriformes - Kun Zhang; Yifan Liu; Jian Chen; Hua Zhang; Li Gong; Lihua Jiang; Liqin Liu; Zhenming Lü; Bingjian Liu (Molecular Biology Reports, 2021)

A plant virus mediates interspecific competition between its insect vectors in Capsicuum annuum - Yong Chen; Xue Zheng; Hui Wei; Yong-Dui Chen; Kuan-Yu Zheng; Ye Mu; Xing-Yue Zhao; Li-Hua Zhao; Yu-Lin Gao; Li-Min Zheng; Jie Zhang (Journal of Pest Science, 2021)

A Fluorogenic and Chromogenic Probe Distinguishes Fluoride Anions and Thiols: Implications for Discrimination of Fluoride-Containing G Series and Sulfur-Containing V Series Nerve Agents - Wei-hui Wu; Xin Wang; Liang Zong; Dan Li; Yan-hua Xiao; Shao-hui Sui; Jian Li; Meng Liu; Gao-yun Chen; Teng Luo; Min Liu; Xin-ming Wang; et al. (Journal of Fluorescence, 2021)

Design of the Blade under Low Flow Velocity for Horizontal Axis Tidal Current Turbine - Jun-Hua Chen; Xian-Cheng Wang; Hao Li; Chu-Hua Jiang; Ling-Jie Bao (Journal of Marine Science and Engineering, 2020)
The blade is the key component for energy capture in horizontal axis tidal current turbine, and the blade’s design is directly related to the efficiency of the power generation device. The seawater flow velocity is a crucial parameter for blade design. Since the seawater velocity changes constantly, it is extremely important to determine the design velocity of the blade. This article proposes a calculation method for the design velocity of the blade so that the designed blade can achieve better energy collection efficiency under a variable flow velocity. This study performed the following investigations: (1) The author tested and analyzed the seawater velocity variation at the experimental site, determining the designed flow velocity via calculations; (2) The author combined the blade element momentum and Wilson’s optimization design method using the MATLAB software to calculate the blade shape parameters and predict the performance under a number of different flow velocity forecasts; (3) When testing the device under sea conditions, the experimental results showed that the performance capture devices and digital projections are basically the same, which verifies the validity and effectiveness of the design method.

Etv5 safeguards trophoblast stem cells differentiation from mouse EPSCs by regulating fibroblast growth factor receptor 2 - Kui Zhu; Yuan Liu; Chen Fan; Mengyao Zhang; Hongxia Cao; Xin He; Na Li; Dianfeng Chu; Fang Li; Min Zou; Jinlian Hua; Huayan Wang; et al. (Molecular Biology Reports, 2020)

MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1 - Xuesong Yang; Dongna Li; Ying-Zi Qi; Wenjing Chen; Chuan-Hua Yang; Yue-Hua Jiang (Molecular and Cellular Biochemistry, 2020)

Straw Incorporation Coupled with Deep Placement of Nitrogen Fertilizer Improved Grain Yield and Nitrogen Use Efficiency in Direct-Seeded Rice - Yunyan Chen; Pingshan Fan; Lin Li; Hua Tian; Umair Ashraf; Zhaowen Mo; Meiyang Duan; Qiantong Wu; Zheng Zhang; Xiangru Tang; Shenggang Pan (Journal of Soil Science and Plant Nutrition, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Larger regional volume of the thalamus in diarrhea-predominant irritable bowel syndrome: a cross-sectional study - Cui Ping Mao; Fen Rong Chen; Hong Hong Sun; Mei Juan Shi; Hua Juan Yang; Xiao Hui Li; Dun Ding (Brain Imaging and Behavior, 2020)

LncRNA NEAT1 accelerates renal mesangial cell injury via modulating the miR-146b/TRAF6/NF-κB axis in lupus nephritis - Li-Hua Zhang; Bin Xiao; Miao Zhong; Qiao Li; Jian-Ying Chen; Jie-Rou Huang; Hui Rao (Cell and Tissue Research, 2020)

Influence of complex topography on magnetotelluric-observed data using three-dimensional numerical simulation: A case from Guangxi area, China - Xiong Bin; Luo Tian-Ya; Chen Long-Wei; Dai Shi-Kun; Xu Zhi-Feng; Li Chang-Wei; Ding Yan-Li; Wang Hong-Hua; Li Jing-He (Applied Geophysics, 2020)

Sphingosylphosphorylcholine alleviates hypoxia-caused apoptosis in cardiac myofibroblasts via CaM/p38/STAT3 pathway - Ying Li; Qi Qi; Wan-cheng Yang; Tian-liang Zhang; Chen-chen Lu; Yu-juan Yao; Wei-hua Kong; Jing Zhao (Apoptosis, 2020)

Solanrubiellin A, a hydroanthraquinone dimer with antibacterial and cytotoxic activity from Solanum lyratum - Hui Chen; Kun Du; Yan-Jun Sun; Zhi-You Hao; Yan-Li Zhang; Jiang Bai; Qing-Hua Wang; Hai-Yu Hu; Wei-Sheng Feng (Natural Product Research, 2020)

Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex - Fen Zheng; Chao Ye; Guo-Wei Wan; Bing Zhou; Ying Tong; Jian-Zhen Lei; Qi Chen; Yue-Hua Li; Yu-Ming Kang; Guo-Qing Zhu (Pflügers Archiv - European Journal of Physiology, 2020)

Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells - Yiran Sun; Libo He; Taoyu Wang; Wan Hua; Huan Qin; Jingjin Wang; Li Wang; Wanqin Gu; Tingting Li; Na Li; Xinanbei Liu; Fang Chen; et al. (Molecular Neurobiology, 2020)

Effect of various doses of 3,4-dimethylpyrazole phosphate on mineral nitrogen losses in two paddy soils - Hua Li; Xiaodong Chen; Chen Liu; Shaoxian Wang; Bin Guo; Ningyu Li; Yuequn Jin; Qinglin Fu; Xinqiang Liang (Journal of Soils and Sediments, 2020)

Photosynthetic properties and biochemical metabolism of Cucurbita moschata genotypes following infection with powdery mildew - Bi-Hua Chen; Wei-Li Guo; He-Lian Yang; Qing-Fei Li; Jun-Guo Zhou; Xin-Zheng Li (Journal of Plant Pathology, 2020)
Powdery mildew (PM) is one of the most important fungal diseases in Cucurbita moschata (pumpkin) cultivation. This experiment was conducted to shed light on the physiological mechanisms of PM resistance in pumpkin cultivars. PM pathogen was inoculated on pumpkin seedlings, PM-susceptible genotype (JJJD) and PM-resistant genotype (inbred line 112–2) to study the PM-fungal growth, plant photosynthetic and biochemical parameters with different intervals of time. The disease index and pathogen growth observed for the PM-infected 112–2 seedlings were milder than those observed for the JJJD seedlings. The net photosynthetic rate (Pn), stomatal conductance (gs) and transpiration rate (Tr) were reduced for both the PM-infected genotypes, while the internal CO 2 concentration (Ci) increased in comparison with the non-infected controls. PM pathogen inoculation impaired the photosynthetic performance in seedlings of both genotypes and this was largely associated with stomatal closure. In comparison with the non-infected controls, the superoxide dismutase (SOD) and β-1,3-glucanase activities were reduced for both the PM-infected genotypes, while the peroxidase (POD) and phenylalanine ammonia lyase (PAL) activities were increased. The catalase (CAT) activity was reduced in the 112–2 genotype and increased in the JJJD genotype after PM pathogen inoculation. Together, our data show that PM resistance in pumpkin seedlings is associated with the maintenance of photosynthetic performance and the regulation of defense-related enzyme activities .

A pair of new diastereoisomeric phenylpropanoid-substituted flavan from the leaves of Ilex centrochinensis - Hui Long; Yu Chen; Ze-Hua Hu; Shao-Jun Zhang; Lu-Jun Li (Natural Product Research, 2020)

Applications and research advance of genome shuffling for industrial microbial strains improvement - Liang Chen; Qiu-Hua Xin; Li-Min Ma; Rui-Fang Li; Ke Bian (World Journal of Microbiology and Biotechnology, 2020)

Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis - Ning Xiao; Tian-long Liu; Hao Li; Hao-chen Xu; Jing Ge; Hong-yan Wen; Cong-xia Bai; Li Song; Ying-ying Sun; Yin-hui Zhang; Ru-tai Hui; Wei-hua Song; et al. (Translational Stroke Research, 2020)

The molecular mechanisms of copper metabolism and its roles in human diseases - Ji Chen; Yunhui Jiang; Hua Shi; Yougong Peng; Xueying Fan; Chenghua Li (Pflügers Archiv - European Journal of Physiology, 2020)

Identification, functional characterization, and estrogen regulation on gonadotropin-releasing hormone in the spotted scat, Scatophagus argus - Hua-pu Chen; Xue-fan Cui; Yao-rong Wang; Zhi-yuan Li; Chang-xu Tian; Dong-neng Jiang; Chun-Hua Zhu; Yong Zhang; Shui-sheng Li; Guang-li Li (Fish Physiology and Biochemistry, 2020)

Puerarin Alleviates Lipopolysaccharide-Induced Myocardial Fibrosis by Inhibiting PARP-1 to Prevent HMGB1-Mediated TLR4-NF-κB Signaling Pathway - Shu-Yuan Ni; Xing-Long Zhong; Ze-Hua Li; Dong-Jian Huang; Wen-Ting Xu; Yan Zhou; Cai-Wen Ou; Min-Sheng Chen (Cardiovascular Toxicology, 2020)

Typical gene expression profile of pseudorabies virus reactivation from latency in swine trigeminal ganglion - Hai-Hua Wang; Jie Liu; Lin-Tao Li; Huan-Chun Chen; Wan-Po Zhang; Zheng-Fei Liu (Journal of NeuroVirology, 2020)

Characteristics of the spike and ORF3 genes of porcine epidemic diarrhea virus in Henan and Shanxi provinces of China - Jian-tao Cui; Han Qiao; Cheng-yao Hou; Hui-Hua Zheng; Xin-Sheng Li; Lan-lan Zheng; Hong-Ying Chen (Archives of Virology, 2020)

Noise does not equal bias in assessing the evolutionary history of the angiosperm flora of China: A response to Qian (2019) - Li‐Min Lu; Hai‐Hua Hu; Dan‐Xiao Peng; Bing Liu; Jian‐Fei Ye; Tuo Yang; Hong‐Lei Li; Miao Sun; Stephen A. Smith; Pamela S. Soltis; Douglas E. Soltis; Zhi‐Duan Chen (Journal of Biogeography, 2020)
In response to our paper on the evolutionary history of the Chinese flora, Qian suggests that certain features of the divergence time estimation employed might have led to biased conclusions in Lu et al (2018). Here, we consider Qian's specific criticisms, explore the extent of uncertainty in the data and demonstrate that (i) no systematic bias toward dates that are too young or too old is detected in Lu et al.; (ii) constraint of the crown age of angiosperms does not bias the generic ages estimated by Lu et al.; and (iii) ages derived from the Chinese regional phylogeny do not bias the conclusions reported by Lu et al. All these analyses confirm that the conclusions reported previously are robust. We argue that, like many large‐scale biodiversity analyses, sources of noise in divergence time estimation are to be expected, but these should not be confused with bias.

Cytotoxic triquinane-type sesquiterpenoids from the endophytic fungus Cerrena sp. A593 - Hong-Xin Liu; Hai-Bo Tan; Yu-Chan Chen; Sai-Ni Li; Hao-Hua Li; Wei-Min Zhang (Natural Product Research, 2020)

Depletion of florfenicol and florfenicol amine in eggs of laying hens and growing pullets after oral administration - Xia Li; Lu Chen; Hui Yue; Hua Feng; Enmin Xu; Xiuli Wei; Xiaoli Han; Ligang Deng; Zengmei Li (Food Additives & Contaminants: Part A, 2020)

A novel function of IRF9 in acute pancreatitis by modulating cell apoptosis, proliferation, migration, and suppressing SIRT1-p53 - Bin-Hua Xue; Yi Liu; Hu Chen; Yun Sun; Wei-Li Yu (Molecular and Cellular Biochemistry, 2020)

Characterization of Pneumocystis jirovecii pneumonia at three tertiary comprehensive hospitals in southern China - Yan-Hui Chen; Xue-Yao Fang; Yue-Ting Li; Yan-Ling Liu; Ya-Ping Hang; Yan-Ping Xiao; Xing-Wei Cao; Qiao-Shi Zhong; Long-Hua Hu (Brazilian Journal of Microbiology, 2020)

Reconstructing the 3D digital core with a fully convolutional neural network - Qiong Li; Zheng Chen; Jian-Jun He; Si-Yu Hao; Rui Wang; Hao-Tao Yang; Hua-Jun Sun (Applied Geophysics, 2020)

A bacterial polysaccharide biosynthesis-related gene inversely regulates larval settlement and metamorphosis of Mytilus coruscus - Li-Hua Peng; Xiao Liang; Rui-Heng Chang; Jia-Yi Mu; Hui-E Chen; Asami Yoshida; Kiyoshi Osatomi; Jin-Long Yang (Biofouling, 2020)

Privet golden leaves adapt unexpectedly well to light changes - Ming Yuan; Bo Huang; Li-Hua Dong; Qiao-Hong Han; Yong Yang; Chun-Bang Ding; Chao Hu; Yang-Er Chen; Zhong-Wei Zhang; Shu Yuan (Horticulture, Environment, and Biotechnology, 2020)

Design and synthesis of novel 7-[( N -substituted-thioureidopiperazinyl)-methyl]-camptothecin derivatives as potential cytotoxic agents - Zi-Long Song; Guan-Zhou Yang; Jun-Cai Li; Ying-Qian Liu; Chen-Jie Yang; Masuo Goto; Zhi-Jun Zhang; Susan L. Morris-Natschke; Hua Liu; Kuo-Hsiung Lee (Natural Product Research, 2020)

Comparative transcriptome analysis reveals a gene expression profile that contributes to rhizome swelling in Panax japonicus var. major - Jun Rong Tang; Ying Chun Lu; Zheng Jie Gao; Wan Ling Song; Kun Hua Wei; Yan Zhao; Qing Yan Tang; Xue Jiao Li; Jun Wen Chen; Guang Hui Zhang; Guang Qiang Long; Wei Fan; et al. (Plant Biosystems, 2020)

Decreased sustained attention, processing speed and verbal learning memory in patients with insomnia in Chinese young and middle-aged adults: a cross-sectional study - Xie Chen; Cai-Lan Hou; Shi-Bin Wang; Zhuo-Hui Huang; Ying-Hua Huang; Xue-Li Li; Fu-Jun Jia (Sleep and Biological Rhythms, 2020)

A review of progress in coupled ocean-atmosphere model developments for ENSO studies in China - Rong-Hua Zhang; Yongqiang Yu; Zhenya Song; Hong-Li Ren; Youmin Tang; Fangli Qiao; Tongwen Wu; Chuan Gao; Junya Hu; Feng Tian; Yuchao Zhu; Lin Chen; et al. (Journal of Oceanology and Limnology, 2020)

MicroRNA-153-3p enhances the sensitivity of chronic myeloid leukemia cells to imatinib by inhibiting B-cell lymphoma-2-mediated autophagy - Yu-Ling Li; Jia-Ming Tang; Xiao-Yun Chen; Bing Luo; Guo-Hua Liang; Qian Qu; Zi-Yuan Lu (Human Cell, 2020)

The association between dioxins and steroid hormones in general adult males: a cross-sectional study in an e-waste region of China - Li Li Shi; Mei Qin Wang; Shoji F. Nakayama; Chau-Ren Jung; Yue Hua Wang; Jing Jian Dong; Chao Chen Ma; Teruhiko Kido; Xian Liang Sun; Hao Feng (Environmental Science and Pollution Research, 2020)

Distinct Characteristics of Bacterial Community in the Soil of Nanshazhou Island, South China Sea - Yong-gan Chen; Zhen-hua Zhang; Hong-wei Luo; Zhen Li; Lai-jun Zhang; Hai Huang (Current Microbiology, 2020)

Crosstalk between PKC and MAPK pathway activation in cardiac fibroblasts in a rat model of atrial fibrillation - Wei-hua Guo; Xian Wang; Mei-sheng Shang; Zhe Chen; Qi Guo; Li Li; Hai-ying Wang; Rong-hui Yu; Chang-sheng Ma (Biotechnology Letters, 2020)

Isolation and characterization of 34 SNP markers in Hucho bleekeri - Yeyu Chen; Huanchao Yang; Quan Gong; Yanling Chen; Quanyu Tu; Hua Li (Conservation Genetics Resources, 2020)

A new diterpenoid alkaloid from Aconitum hemsleyanum - Zhi-Hui Luo; Yang Chen; Xin-Yi Sun; Hua Fan; Wei Li; Liang Deng; Tian-Peng Yin (Natural Product Research, 2020)

Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation - Yun Qiu; Fen Zheng; Chao Ye; Ai-Dong Chen; Jue-Jin Wang; Qi Chen; Yue-Hua Li; Yu-Ming Kang; Guo-Qing Zhu (Neuroscience Bulletin, 2020)

Analysis of an improved workflow of endoscope reprocessing for bedside endoscopic diagnosis and treatment on COVID-19 patients - Qing Gu; Hua-fen Wang; Ying Fang; Ye Lu; Zhe Shen; Yan Wang; Xin Wu; Li Cen; Yi-shu Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Efficacy of internet-based integrated intervention on depression and anxiety symptoms in patients with COVID-19 - Ning Wei; Bo-chao Huang; Shao-jia Lu; Jian-bo Hu; Xiao-yi Zhou; Chan-chan Hu; Jing-kai Chen; Jin-wen Huang; Shu-guang Li; Zheng Wang; Dan-dan Wang; Yi Xu; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Dialectical behavior therapy-based psychological intervention for woman in late pregnancy and early postpartum suffering from COVID-19: a case report - Jin-wen Huang; Xiao-yi Zhou; Shao-jia Lu; Yi Xu; Jian-bo Hu; Man-li Huang; Hua-fen Wang; Chan-chan Hu; Shu-guang Li; Jing-kai Chen; Zhong Wang; Shao-hua Hu; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Nanobody against PDL1 - Shufeng Li; Kunpeng Jiang; Ting Wang; Wei Zhang; Minke Shi; Baojun Chen; Zichun Hua (Biotechnology Letters, 2020)

The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line - Gen-Meng Yang; Lu Li; Feng-Lin Xue; Chen-Li Ma; Xiao-Feng Zeng; Yong-Na Zhao; Dong-Xian Zhang; Yang Yu; Qian-Wen Yan; Yi-Qing Zhou; Shi-Jun Hong; Li-Hua Li (Neurotoxicity Research, 2020)

Tracing solute sources and carbon dynamics under various hydrological conditions in a karst river in southwestern China - Jing Liu; Bo Chen; Zhu-Yan Xu; Yuan Wei; Zhi-Hua Su; Rui Yang; Yong-Xue Ji; Xiao-Dan Wang; Li-Li Zhang; Ning An; Fei Yang (Environmental Science and Pollution Research, 2020)

Multifunctionality of biocrusts is positively predicted by network topologies consistent with interspecies facilitation - Hua Li; Da Huo; Weibo Wang; Youxin Chen; Xiaoli Cheng; Gongliang Yu; Renhui Li (Molecular Ecology, 2020)
The potential of biodiversity loss to impair the delivery of ecosystem services has motived ecologists to better understand the relationship between biodiversity and ecosystem functioning. Although increasing evidence underlines the collective contribution of different biodiversity components on the simultaneous performance of multiple functions (multifunctionality), we know little about the trade‐offs between individual diversity effects and the extent to which they determine multifunctionality differentially. Here, at a subcontinental scale of 62 dryland sites, we show in phototrophic microbiota of biological soil crusts (biocrusts) that, whereas richness alone is unable to guarantee the maxima of multifunctional performance, interspecies facilitation and compositional identity are particularly stronger but often neglected predictors. The inconsistent effects of different biodiversity components imply that soil multifunctionality can be lost despite certain species remaining present. Moreover, we reveal a significant empirical association between species functional importance and its topological feature in co‐occurrence networks, indicating a functional signal of species interaction. Nevertheless, abundant species tend to isolate and merely interact within small topological structures, but rare species were tightly connected in complicated network modules. Our findings suggest that abundant and rare species of soil phototrophs exhibit distinct functional relevance. These results give a comprehensive view of how soil constructive species drive multifunctionality in biocrusts and ultimately promote a deeper understanding of the consequences of biodiversity loss in real‐world ecosystems.

Potential Genes Related to Levofloxacin Resistance in Mycobacterium tuberculosis Based on Transcriptome and Methylome Overlap Analysis - Hai-cheng Li; Hui-xin Guo; Tao Chen; Wei Wang; Zhu-hua Wu; Liang Chen; Hui-zhong Wu; Gao-po Xu; Xun-xun Chen; Lin Zhou (Journal of Molecular Evolution, 2020)
Drug-resistant Mycobacterium tuberculosis ( M. tuberculosis ) has become an increasingly serious public health problem and has complicated tuberculosis (TB) treatment. Levofloxacin (LOF) is an ideal anti-tuberculosis drug in clinical applications. However, the detailed molecular mechanisms of LOF-resistant M. tuberculosis in TB treatment have not been revealed. Our study performed transcriptome and methylome sequencing to investigate the potential biological characteristics of LOF resistance in M. tuberculosis H37Rv. In the transcriptome analysis, 953 differentially expressed genes (DEGs) were identified; 514 and 439 DEGs were significantly downregulated and upregulated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 97 pathways were enriched in this study. In the methylome analysis, 239 differentially methylated genes (DMGs) were identified; 150 and 89 DMGs were hypomethylated and hypermethylated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 74 pathways were enriched in this study. The overlap study suggested that 25 genes were obtained. It was notable that nine genes expressed downregulated mRNA and upregulated methylated levels, including pgi , fadE4 , php , cyp132 , pckA , rpmB1 , pfkB , acg , and ctpF , especially cyp132 , pckA , and pfkB , which were vital in LOF-resistant M. tuberculosis H37Rv. The overlapping genes between transcriptome and methylome could be essential for studying the molecular mechanisms of LOF-resistant M. tuberculosis H37Rv. These results may provide informative evidence for TB treatment with LOF.

Development of a loop-mediated isothermal amplification (LAMP) assay for rapid detection of Pseudomonas syringae pv. tomato in planta - Zhen-Dong Chen; Hua-Jun Kang; A-Li Chai; Yan-Xia Shi; Xue-Wen Xie; Lei Li; Bao-Ju Li (European Journal of Plant Pathology, 2020)

Grazing Offsets Nitrogen Enrichment Effects on Species Richness by Promoting the Random Colonization of Local Species in an Alpine Grassland - Ming-Hua Song; Jin Chen; Xing-Liang Xu; Yi-Kang Li; Jun-Qin Gao; Hua OuYang (Ecosystems, 2020)

Chemical Stimulation of Renal Tissue Induces Sympathetic Activation and a Pressor Response via the Paraventricular Nucleus in Rats - Chao Ye; Yun Qiu; Feng Zhang; Ai-Dong Chen; Hong Zhou; Jue-Jin Wang; Qi Chen; Yue-Hua Li; Yu-Ming Kang; Guo-Qing Zhu (Neuroscience Bulletin, 2020)

Utilization of pre-existing competent and barren quartz veins as hosts to later orogenic gold ores at Huangjindong gold deposit, Jiangnan Orogen, southern China - Liang Zhang; David I. Groves; Li-Qiang Yang; Si-Chen Sun; Roberto F. Weinberg; Jiu-Yi Wang; Sheng-Gang Wu; Lei Gao; Lan-Ling Yuan; Rong-Hua Li (Mineralium Deposita, 2020)

Vertical variation in Vibrio community composition in Sansha Yongle Blue Hole and its ability to degrade macromolecules - Bei Li; Jiwen Liu; Shun Zhou; Liang Fu; Peng Yao; Lin Chen; Zuosheng Yang; Xiaolei Wang; Xiao-Hua Zhang (Marine Life Science & Technology, 2020)
With the advantages of wide distribution, fast growth, and broad metabolic spectrum to organic carbon compounds, Vibrio may play an important role in organic carbon cycling. However, the ecological roles of Vibrio in many marine environments have not been explored. Here, the world’s deepest ‘blue hole’, the Sansha Yongle Blue Hole (SYBH) in the South China Sea, which is a geographically semi-enclosed environment featuring unique chemical characters, was investigated. The abundance, diversity and carbon source utilization capability of Vibrio were studied by quantification and high-throughput sequencing of Vibrio specific 16S rRNA genes and cultivation methods. The abundance of Vibrio in water column of the SYBH ranged from 3.78 × 10 4 to 7.35 × 10 6 16S rRNA gene copies L −1 . Free-living Vibrio was more abundant than particle-associated Vibrio (~ 1.20 × 10 6 versus~ 2.68 × 10 5 gene copies L −1 ), indicating that Vibrio prefers a free-living life style. The Vibrio assemblages showed clear vertical stratification and could be divided into three groups: aerobic-transition, middle anaerobic and bottom anaerobic zones. Dissolved oxygen (DO), temperature, pH and salinity were the main environmental factors affecting the abundance and community composition. Cultivated Vibrio demonstrated a degrading capability to various macromolecular substrates, including starch, Tween 20/40/80, DNA, gelatin, alginate, casein, chitin, lecithin, κ-carrageenan, mannan, xylan and hyaluronic acid. This suggests that Vibrio could produce a variety of highly active extracellular enzymes. Our study provides new insights into the distribution pattern and possible role in carbon cycle of Vibrio in the unique environment of a ‘blue hole’.

Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression - Fang Yang; Wang-wang Liu; Hui Chen; Jia Zhu; Ai-hua Huang; Fei Zhou; Yi Gan; Yan-hua Zhang; Li Ma (Journal of Zhejiang University-SCIENCE B, 2020)

Modified stepwise mini-incision microdissection testicular sperm extraction: a useful technique for patients with a history of orchidopexy affected by non-obstructive azoospermia - Peng Li; Chen-cheng Yao; Er-lei Zhi; Yuan Xu; Zhong Wan; Ying-chuan Jiang; Yu-hua Huang; Yue-hua Gong; Hui-xing Chen; Ru-hui Tian; Chao Yang; Liang-yu Zhao; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Hirsutella sinensis inhibits NLRP3 inflammasome activation to block aristolochic acid-induced renal tubular epithelial cell transdifferentiation - Min Yu; Yu-lin Man; Meng-hua Chen; Li-hua Wu; Yi Zhou; Xiao-ling Zhou; Na Chen; Rui Ma; Li-na Sun (Human Cell, 2020)

Evaluation of the genetic diversity of mango (Mangifera indica L.) seedling germplasm resources and their potential parents with start codon targeted (SCoT) markers - Li Zhou; Xin-Hua He; Hai-Xia Yu; Mei-Yan Chen; Yan Fan; Xiu-Juan Zhang; Zhong-Bing Fang; Cong Luo (Genetic Resources and Crop Evolution, 2020)

Quantification of restricting factors of agricultural development in Min County of Gansu, China - Yong Chen; Li-hua Zhou (Journal of Mountain Science, 2020)

Seasonal rainfall forecasting for the Yangtze River basin using statistical and dynamical models - Shuni Qian; Jie Chen; Xiangquan Li; Chong‐Yu Xu; Shenglian Guo; Hua Chen; Xushu Wu (International Journal of Climatology, 2020)
Summer monsoon rainfall forecasting in the Yangtze River basin is highly valuable for water resource management and for the control of floods and droughts. However, improving the accuracy of seasonal forecasting remains a challenge. In this study, a statistical model and four dynamical global circulation models (GCMs) are applied to conduct seasonal rainfall forecasts for the Yangtze River basin. The statistical forecasts are achieved by establishing a linear regression relationship between the sea surface temperature (SST) and rainfall. The dynamical forecasts are achieved by downscaling the rainfall predicted by the four GCMs at the monthly and seasonal scales. Historical data of monthly SST and GCM hindcasts from 1982 to 2010 are used to make the forecast. The results show that the SST‐based statistical model generally outperforms the GCM simulations, with higher forecasting accuracy that extends to longer lead times of up to 12 months. The SST statistical model achieves a correlation coefficient up to 0.75 and the lowest mean relative error of 6%. In contrast, the GCMs exhibit a sharply decreasing forecast accuracy with lead times longer than 1 month. Accordingly, the SST statistical model can provide reliable guidance for the seasonal rainfall forecasts in the Yangtze River basin, while the results of GCM simulations could serve as a reference for shorter lead times. Extensive scope exists for further improving the rainfall forecasting accuracy of GCM simulations.

Water and heat availability are drivers of the aboveground plant carbon accumulation rate in alpine grasslands on the Tibetan Plateau - Jian Sun; Tian‐Cai Zhou; Miao Liu; You‐Chao Chen; Guo‐Hua Liu; Ming Xu; Pei‐Li Shi; Fei Peng; Atsushi Tsunekawa; Yu Liu; Xiao‐Dan Wang; Shi‐Kui Dong; et al. (Global Ecology and Biogeography, 2020)
Aim Climate change is expected to have important effects on plant phenology and carbon storage, with further shifts predicted in the future. Therefore, we proposed the community carbon accumulation rate (CAR) from the start of the growing season (SOS) to the peak of the growing season (POS) to fill the gap that the dynamic interactions between plant phenology and plant carbon research. Location Tibetan Plateau. Major taxa Alpine grassland plants. Time period 2015. Methods We conducted a transect survey across grasslands to measure community aboveground net primary production and carbon concentration. Additionally, phenology indicator data (SOS and POS) were extracted from the Global Inventory Modeling and Mapping Studies (GIMMS) normalized difference vegetation index version 3 database. Next, we used ‘ changepoint ’ analysis to detect the patterns of CARs, and performed linear regression and one‐way ANOVA to explore the variability of CARs in response to the environmental factors. Ultimately, the total effects of environmental factors on CARs were illustrated by a structural equation model. Results Our results indicated that three CAR patterns were detected, which are low‐CAR (0.15 g/m 2 /day), medium‐CAR (0.31 g/m 2 /day) and high‐CAR (0.84 g/m 2 /day) patterns. We found that the availabilities of water and heat mediated CARs by regulating soil nutrition variability, and that drought climate and insufficient soil resources co‐constrained the community CAR at long time‐scales. In contrast, high CAR could be explained by more water and heat availability via either direct or indirect effects on soil moisture and soil nutrients. Main conclusions Our findings highlight that water and heat availability are critical driving factors in ecological carbon accumulation processes undergoing climate change. Meanwhile, the vegetative phenology also has important effect on carbon accumulation. Consequently, we propose incorporating the dynamic interactions between plant phenology and plant carbon into the ecological carbon cycle model to improve our understanding of resource utilization and survival strategies of plants under environmental change.

Phenolic glycoside constituents from Brassica rapa flowers and their α -glucosidase inhibitory activity - Chun-Chao Zhao; Jie Shen; Jia Chen; Jian-Hua Shao; Ke-Huan Li; Wen-Yan Gu; Ben-Jie Miao (Natural Product Research, 2019)

Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia - Liansheng Zhao; Huijuan Wang; Yamin Zhang; Jinxue Wei; Peiyan Ni; Hongyan Ren; Gang Li; Qiang Wang; Gavin P Reynolds; Weihua Yue; Wei Deng; Hao Yan; et al. (Neuroscience Bulletin, 2019)

Integrated 3D bioprinting-based geometry-control strategy for fabricating corneal substitutes - Bin Zhang; Qian Xue; Han-yi Hu; Meng-fei Yu; Lei Gao; Yi-chen Luo; Yang Li; Jin-tao Li; Liang Ma; Yu-feng Yao; Hua-yong Yang (Journal of Zhejiang University-SCIENCE B, 2019)

MiR-195 inhibits migration, invasion and epithelial-mesenchymal transition (EMT) of endometrial carcinoma cells by targeting SOX4 - Xiaomeng Zhao; Lili Dai; Qifang Yue; Hua Wang; Xu Wang; Yuan Li; Ran Chen (Journal of Biosciences, 2019)

CRISPR/Cas9 facilitates genomic editing for large-scale functional studies in pluripotent stem cell cultures - Xiao-Fei Li; Yong-Wei Zhou; Peng-Fei Cai; Wei-Cong Fu; Jin-Hua Wang; Jin-Yang Chen; Qi-Ning Yang (Human Genetics, 2019)

Comparative transcriptome analysis of male and female gonads reveals sex-biased genes in spotted scat (Scatophagus argus) - Fei-Xiang He; Dong-Neng Jiang; Yuan-Qing Huang; Umar Farouk Mustapha; Wei Yang; Xue-Fan Cui; Chang-Xu Tian; Hua-Pu Chen; Hong-Juan Shi; Si-Ping Deng; Guang-Li Li; Chun-Hua Zhu (Fish Physiology and Biochemistry, 2019)

The complete chloroplast genome of the daimyo oak, Quercus dentata Thunb. - Hua-Lei Hu; Jing-Yu Zhang; Yu-Ping Li; Lu Xie; Dong-Bin Chen; Qun Li; Yan-Qun Liu; Shu-Rong Hui; Li Qin (Conservation Genetics Resources, 2019)

Rapid diversification of alpine bamboos associated with the uplift of the Hengduan Mountains - Xia‐Ying Ye; Peng‐Fei Ma; Guo‐Qian Yang; Cen Guo; Yu‐Xiao Zhang; Yun‐Mei Chen; Zhen‐Hua Guo; De‐Zhu Li (Journal of Biogeography, 2019)
Aim The Hengduan Mountains (HDM) of southwest China is a biodiversity hotspot and harbours one of the world's richest temperate floras. However, the origin and evolution of its biota remain largely unresolved. Here we explore the impact of mountain uplift on the diversification process of biodiversity in this hotspot using alpine bamboos. Location The HDM region, southwest China. Taxon Alpine bamboos. Methods We used ddRAD‐seq data from the most complete sampling of alpine bamboos undertaken to date (79% of the species diversity), to investigate their evolutionary history. The ancestral area of these bamboos was reconstructed using a time‐calibrated phylogeny in BioGeoBEARS and diversification rates were inferred using BAMM analyses. In addition, the impact of mountain uplift on the divergence of alpine bamboos was evaluated using trait‐dependent models of diversification. Results The alpine bamboos were strongly supported as monophyletic, and the relationships within them were robustly resolved. Fargesia was found to be polyphyletic and Yushania was resolved as monophyletic. Alpine bamboos originated outside the HDM region during the late Miocene, and spread to this region in the Pliocene, undergoing a significant acceleration in net diversification, which is temporally congruent with the orogeny. The speciation rate increased with altitude and a high diversification rate, estimated to be 0.75 species per million years, was detected for alpine bamboos distributed in high elevations. Main Conclusions Our study demonstrates that heterogeneous mountain habitats and geographical isolation of alpine bamboos, which have limited dispersal ability, are important drivers for their rapid diversification. This study also highlights the power of complementary analyses in revealing the link between species diversification and past geological changes.

Multi‐model analysis of climate impacts on plant photosynthesis in China during 2000–2015 - Hao Yan; Shao‐Qiang Wang; Jun‐Bang Wang; Yun Cao; Ling‐Ling Xu; Men‐Xin Wu; Lu Cheng; Liu‐Xi Mao; Feng‐Hua Zhao; Xian‐Zhou Zhang; Yun‐Fen Liu; Yan‐Fen Wang; et al. (International Journal of Climatology, 2019)
Differences, arising from differences in gross primary production (GPP) model structures and driving forces, have fuelled arguments concerning interannual changes of GPP in China since 2000. To better investigate the interannual variability of GPP and its covariance with climate factors in China, this study adopted a multi‐model analysis based on three GPP models (i.e., Terrestrial Ecosystem Carbon flux model [TEC], Breathing Earth System Simulator model [BESS], and MOD17 GPP model). The results show that annual GPP in China increased by 0.021–0.057 Pg C year −1 from 2000 to 2015 attributable to atmospheric‐CO 2 fertilization effects and favourable climate change, that is, increasing precipitation ( P r ) and temperature ( T a ). However, northern China and southern China had a large difference in the amplitude of these GPP changes; annual GPP increased by 0.017–0.039 Pg C year −1 in northern China but only 0.001–0.018 Pg C year −1 in southern China. Northern China and southern China occupy contrasting climate zones and this contrast produced different interannual variability of GPP through different mechanisms. Northern China has a dry climate with GPP changes sensitive to P r . As a result, more P r along with higher T a in northern China produced the strong uptrend of GPP from 2000 to 2015. In contrast, southern China has a wet climate with its GPP sensitive to solar radiation and T a . For the interval of 2000–2015, decreasing radiation plus drought exerted a negative influence on GPP in southern China. This study highlights the diverse mechanisms in which climate change affects GPP in dry and wet climate zones. A robust multi‐model analysis is preferred to reduce uncertainties arising from a single GPP model and its driving data.

New benzyl-aporphine alkaloids from Thalictrum cultratum - Wenjia Kang; Jianyong Li; Dahong Li; Zhanlin Li; Shengshuang Chen; Huiming Hua; Jiao Bai (Natural Product Research, 2019)

Two episodes of REE mineralization in the Qinling Orogenic Belt, Central China: in-situ U-Th-Pb dating of bastnäsite and monazite - Wei Zhang; Wei Terry Chen; Jian-Feng Gao; Hua-Kai Chen; Jing-Hui Li (Mineralium Deposita, 2019)

Accumulation and Depuration of Nonylphenol and Its Effect on the Expressions of Vitellogenin and Vitellogenin Receptor in Freshwater Prawn Macrobrachium rosenbergii - Hui Guo; Luan-luan Chen; Guang-li Li; Si-ping Deng; Chun-hua Zhu (Bulletin of Environmental Contamination and Toxicology, 2019)

Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study - Li-Yin Zhang; Deng-Lin Zhan; Yuan-Yuan Chen; Wei-Hua Wang; Cheng-Yong He; Yi Lin; Yu-Chun Lin; Zhong-Ning Lin (Archives of Toxicology, 2019)

Artemisinin suppresses hepatocellular carcinoma cell growth, migration and invasion by targeting cellular bioenergetics and Hippo-YAP signaling - Yujie Li; Jing Lu; Qin Chen; Shengnan Han; Hua Shao; Pingyi Chen; Qiumei Jin; Mingyue Yang; Fugen Shangguan; Mingming Fei; Lu Wang; Yongzhang Liu; et al. (Archives of Toxicology, 2019)

Spatiotemporal characteristics of precipitation concentration and the possible links of precipitation to monsoons in China from 1960 to 2015 - Ya Huang; Hao Wang; Wei-hua Xiao; Li-hua Chen; Heng Yang (Theoretical and Applied Climatology, 2019)

X-linked hyper-IgM syndrome complicated with interstitial pneumonia and liver injury: a new mutation locus in the CD40LG gene - Tian-Jiao Wang; Li-Fang Wu; Junguo Chen; Wen Zhu; Hua Wang; Xiao-Lin Liu; Yi-Qun Teng (Immunologic Research, 2019)

Identifying spatial heterogeneity of groundwater and its response to anthropogenic activities - Zhi-wei Wang; Hua-wei Chen; Fu-lin Li (Environmental Science and Pollution Research, 2019)

Unraveling prevalence and public health risks of arsenic, uranium and co-occurring trace metals in groundwater along riverine ecosystem in Sindh and Punjab, Pakistan - Waqar Ali; Muhammad Wajahat Aslam; Caiyan Feng; Muhammad Junaid; Kamran Ali; Shehong Li; Zhe Chen; Ziheng Yu; Atta Rasool; Hua Zhang (Environmental Geochemistry and Health, 2019)

Serratia microhaemolytica sp. nov., isolated from an artificial lake in Southern China - Juan Wang; Min-Ling Zheng; Jian-Yu Jiao; Wei-Jia Wang; Shuai Li; Min Xiao; Cha Chen; Ping-Hua Qu; Wen-Jun Li (Antonie van Leeuwenhoek, 2019)

Insecticidal and α -glucosidase inhibitory activities of chemical constituents from Viburnum fordiae Hance - Jian-Hua Shao; Jia Chen; Chun-Chao Zhao; Jie Shen; Wen-Yan Liu; Wen-Yan Gu; Ke-Huan Li (Natural Product Research, 2019)

Advance in biological activities of natural guaiane-type sesquiterpenes - Gang-Hua Ma; Kai-Xian Chen; Liu-Qiang Zhang; Yi-Ming Li (Medicinal Chemistry Research, 2019)

Isolation and identification of new prenylated acetophenone derivatives from Acronychia oligophlebia - Qian-Wen Niu; Neng-Hua Chen; Zhong-Nan Wu; Ding Luo; Ying-Ying Li; Yu-Bo Zhang; Qing-Guo Li; Yao-Lan Li; Guo-Cai Wang (Natural Product Research, 2019)

Association of Genetic Polymorphisms with Age at Onset in Han Chinese Patients with Bipolar Disorder - Shao-Hua Hu; Yu-Qing Han; Ting-Ting Mou; Man-Li Huang; Jian-Bo Lai; Chee H Ng; Jing Lu; Qiao-Qiao Lu; Qiu-Yan Lin; Yu-Zhi Zhang; Jian-Bo Hu; Ning Wei; et al. (Neuroscience Bulletin, 2019)

Ginsenoside Rg1 Prevents Chemotherapy-Induced Cognitive Impairment: Associations with Microglia-Mediated Cytokines, Neuroinflammation, and Neuroplasticity - Dong-Dong Shi; Yu-Hua Huang; Cora Sau Wan Lai; Celia M. Dong; Leon C. Ho; Xiao-Yang Li; Ed X. Wu; Qi Li; Xiao-Min Wang; Yong-Jun Chen; Sookja Kim Chung; Zhang-Jin Zhang (Molecular Neurobiology, 2019)

Residue, dissipation, and safety evaluation of etoxazole and pyridaben in Goji berry under open-field conditions in the China’s Qinghai–Tibet Plateau - Hongyu Chen; Wei Li; Liangzhi Guo; Hua Weng; Youhai Wei; Qingyun Guo (Environmental Monitoring and Assessment, 2019)

Cloud Radiative Feedbacks during the ENSO Cycle Simulated by CAMS-CSM - Lin Chen; Lijuan Hua; Xinyao Rong; Jian Li; Lu Wang; Guo Zhang; Ming Sun; Zi’an Ge (Journal of Meteorological Research, 2019)

Performance of Post-Processed Methods in Hydrological Predictions Evaluated by Deterministic and Probabilistic Criteria - Xiang-Quan Li; Jie Chen; Chong-Yu Xu; Lu Li; Hua Chen (Water Resources Management, 2019)

Improved recombinant protein production by regulation of transcription and protein transport in Chinese hamster ovary cells - Kaiming Chen; Dong Li; Hongwen Li; Bing Li; Ruiqin Wang; Lingxiao Jiang; Lei Huang; Xiaoqing Xu; Jie Li; Fei Teng; Cizhong Jiang; Hua Gu; et al. (Biotechnology Letters, 2019)

Predicting the cytotoxicity of disinfection by-products to Chinese hamster ovary by using linear quantitative structure–activity relationship models - Li-Tang Qin; Xin Zhang; Yu-Han Chen; Ling-Yun Mo; Hong-Hu Zeng; Yan-Peng Liang; Hua Lin; Dun-Qiu Wang (Environmental Science and Pollution Research, 2019)

Pseudofrancisella aestuarii gen. nov., sp. nov., a novel member of the family Francisellaceae isolated from estuarine seawater - Min-Ling Zheng; Jian-Yu Jiao; Lei Dong; Ming-Xian Han; Liang-Hui Li; Min Xiao; Cha Chen; Ping-Hua Qu; Wen-Jun Li (Antonie van Leeuwenhoek, 2019)

Novel hepacivirus in Asian house shrew, China - Hua Guo; Chunlin Cai; Bo Wang; Fei Zhuo; Rendi Jiang; Ning Wang; Bei Li; Wei Zhang; Yan Zhu; Yi Fan; Wushen Chen; Weihong Chen; et al. (Science China Life Sciences, 2019)

Long-term straw mulch effects on crop yields and soil organic carbon fractions at different depths under a no-till system on the Chengdu Plain, China - Zijun Zhou; Xiangzhong Zeng; Kun Chen; Zhu Li; Song Guo; Yuxian Shangguan; Hua Yu; Shihua Tu; Yusheng Qin (Journal of Soils and Sediments, 2019)

Analysis of genetic variation of porcine circovirus type 2 within pig populations in central China - Peng-Li Xu; Yu Zhao; Hui-Hua Zheng; Run-Bo Tian; Hao-Ying Han; Hong-Ying Chen; Lan-Lan Zheng (Archives of Virology, 2019)

Immunity induced by recombinant attenuated IHNV (infectious hematopoietic necrosis virus)‐G N438A expresses VP2 gene‐encoded IPNV (infectious pancreatic necrosis virus) against both pathogens in rainbow trout - Yaping Chen; Mengting Guo; Yanxue Wang; Xiaojing Hua; Shuai Gao; Yuting Wang; Dechuan Li; Wen Shi; Lijie Tang; Yijing Li; Min Liu (Journal of Fish Diseases, 2019)
Infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV) are important pathogens in rainbow trout farming worldwide. Their co‐infection is also common, which causes great economic loss in juvenile salmon species. Development of a universal virus vaccine providing broadly cross‐protective immunity will be of great importance. In this study, we generated two recombinant (r) virus (rIHNV‐N438A‐ΔNV‐EGFP and rIHNV‐N438A‐ΔNV‐VP2) replacing the NV gene of the backbone of rIHNV at the single point mutation at residue 438 with an efficient green fluorescent protein ( EGFP ) reporter gene and antigenic VP2 gene of IPNV. Meanwhile, we tested their efficacy against the wild‐type (wt) IHNV HLJ‐09 virus and IPNV serotype Sp virus challenge. The relative per cent survival rates of two recombinant viruses against (wt) IHNV HLJ‐09 virus challenge were 84.6% and 81.5%, respectively. Simultaneously, the relative per cent survival rate of rIHNV‐N438A‐ΔNV‐VP2 against IPNV serotype Sp virus challenge was 88.9%. It showed the two recombinant viruses had high protection rates and induced a high level of antibodies against IHNV or IPNV. Taken together, these results suggest the VP2 gene of IPNV can act as candidate gene for vaccine and attenuated multivalent live vaccines and molecular marker vaccines have potential application for viral vaccine.

Successful Treatment of Eczema-Like Mucormycosis in a Child by Combination of Intravenous Drip and Percutaneous Injection Amphotericin B - Mei-hua Fu; Jia Liu; Guan-zhao Liang; Cheng-rang Li; Xiao-mei Zhu; Le Wang; Hao Chen; Wen-long Hu; Gui-xia Lv; Wei-da Liu (Mycopathologia, 2019)

Field-evolved resistance and cross-resistance of the two-spotted spider mite, Tetranychus urticae, to bifenazate, cyenopyrafen and SYP-9625 - Jin-Cui Chen; Ya-Jun Gong; Pan Shi; Ze-Hua Wang; Li-Jun Cao; Peng Wang; Shu-Jun Wei (Experimental and Applied Acarology, 2019)

Ethyl lucidenates A reverses P-glycoprotein mediated vincristine resistance in K562/A02 cells - Peng Li; Shi-yu Chen; Shao-xin Shen; Ling-xue Liu; Jian-hua Xu; Zhi-qiang Zhang (Natural Product Research, 2019)

Relationship between polymorphisms of the lipid metabolism-related gene PLA2G16 and risk of colorectal cancer in the Chinese population - Xiao-Nv Xie; Jing Yu; Li-Hua Zhang; Zhi-Ying Luo; Dong-Sheng Ouyang; Ling-Jie Zheng; Chun-Yang Wang; Li Yang; Ling Chen; Zhi-Rong Tan (Functional & Integrative Genomics, 2019)

Landslide integrated characteristics and susceptibility assessment in Rongxian county of Guangxi, China - Li-ping Liao; Ying-yan Zhu; Yan-lin Zhao; Hai-tao Wen; Yun-chuan Yang; Li-hua Chen; Shao-kun Ma; Ying-zi Xu (Journal of Mountain Science, 2019)

A predictive deconvolution method for non-white-noise reflectivity - De-Ying Wang; Xue Kong; Lie-Qian Dong; Li-Hua Chen; Yong-Jun Wang; Xiao-Chen Wang (Applied Geophysics, 2019)

Correction to: Magnesium deficiency affects secondary lignification of the vascular system in Citrus sinensis seedlings - Jing-Hao Huang; Jing Xu; Xin Ye; Tu-Yan Luo; Li-Hua Ren; Guo-Cheng Fan; Yi-Ping Qi; Qiang Li; Rhuanito S. Ferrarezi; Li-Song Chen (Trees, 2019)

Magnesium deficiency affects secondary lignification of the vascular system in Citrus sinensis seedlings - Jing-Hao Huang; Jing Xu; Xin Ye; Tu-Yan Luo; Li-Hua Ren; Guo-Cheng Fan; Yi-Ping Qi; Qiang Li; Rhuanito S. Ferrarezi; Li-Song Chen (Trees, 2019)

Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides - Qing-Yan Tang; Geng Chen; Wan-Ling Song; Wei Fan; Kun-Hua Wei; Si-Mei He; Guang-Hui Zhang; Jun-Rong Tang; Ying Li; Yuan Lin; Sheng-Chao Yang (Planta, 2019)

Organic carbon quality, composition of main microbial groups, enzyme activities, and temperature sensitivity of soil respiration of an acid paddy soil treated with biochar - Junhui Chen; De Chen; Qiufang Xu; Jeffry J. Fuhrmann; Lianqing Li; Genxing Pan; Yongfu Li; Hua Qin; Chenfei Liang; Xuan Sun (Biology and Fertility of Soils, 2019)

An Assessment of ENSO Stability in CAMS Climate System Model Simulations - Lijuan Hua; Lin Chen; Xinyao Rong; Jian Li; Guo Zhang; Lu Wang (Journal of Meteorological Research, 2019)

Calcium-dependent protein kinase CPK9 negatively functions in stomatal abscisic acid signaling by regulating ion channel activity in Arabidopsis - Dong-Hua Chen; Hui-Ping Liu; Chun-Long Li (Plant Molecular Biology, 2019)

The Influence of Cellulosic Polymer’s Variables on Dissolution/Solubility of Amorphous Felodipine and Crystallization Inhibition from a Supersaturated State - Nian-Qiu Shi; Ying Jin; Yong Zhang; Xiao-Xia Che; Xiao Xiao; Gui-Hua Cui; Yu-Zhou Chen; Bo Feng; Zheng-Qiang Li; Xian-Rong Qi (AAPS PharmSciTech, 2019)

β2-AR regulates the expression of AKR1B1 in human pancreatic cancer cells and promotes their proliferation via the ERK1/2 pathway - Ming-Bing Xiao; Dan-Dan Jin; Yu-Jie Jiao; Wen-Kai Ni; Jin-Xia Liu; Li-Shuai Qu; Cui-Hua Lu; Run-Zhou Ni; Feng Jiang; Wei-Chang Chen (Molecular Biology Reports, 2018)

Contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of Alzheimer’s disease - Ni Gao; Li-Xin Tao; Jian Huang; Feng Zhang; Xia Li; Finbarr O’Sullivan; Si-Peng Chen; Si-Jia Tian; Gehendra Mahara; Yan-Xia Luo; Qi Gao; Xiang-Tong Liu; et al. (Metabolic Brain Disease, 2018)

Positive PCNA and Ki-67 Expression in the Testis Correlates with Spermatogenesis Dysfunction in Fluoride-Treated Rats - Wen-peng Zhao; Hong-wei Wang; Jing Liu; Pan-pan Tan; Xiang-long Luo; Shi-quan Zhu; Xue-li Chen; Bian-hua Zhou (Biological Trace Element Research, 2018)

The CAMS Climate System Model and a Basic Evaluation of Its Climatology and Climate Variability Simulation - Xinyao Rong; Jian Li; Haoming Chen; Yufei Xin; Jingzhi Su; Lijuan Hua; Tianjun Zhou; Yanjun Qi; Zhengqiu Zhang; Guo Zhang; Jianduo Li (Journal of Meteorological Research, 2018)

An Assessment of CAMS-CSM in Simulating Land–Atmosphere Heat and Water Exchanges - Guo Zhang; Jianduo Li; Xinyao Rong; Yufei Xin; Jian Li; Haoming Chen; Jingzhi Su; Lijuan Hua (Journal of Meteorological Research, 2018)

Bhargavaea changchunensis sp. nov. isolated from soil in China - Feng-Hua Tian; Dong-Yu Fan; Chen Zhang; Chuan-Wen Jia; Wei Gao; Yu Li; Chang-Tian Li (Archives of Microbiology, 2018)

Acute effect of fine and coarse particular matter on cardiovascular visits in Ningbo, China - Pei-wen Zheng; Peng Shen; Zhen-hua Ye; Zhen-yu Zhang; Peng-fei Chai; Die Li; Ming-juan Jin; Meng-Ling Tang; Huai-chu Lu; Hong-bo Lin; Jian-bing Wang; Kun Chen (Environmental Science and Pollution Research, 2018)

Presence of rat bocavirus in oropharyngeal and fecal samples from murine rodents in China - Yi-Quan Xiong; Jun-Hua Zhou; Min-Yi Zhang; Fang-Fei You; Dong-Liang Li; Qing Chen (Archives of Virology, 2018)

Three new 3,4-seco-cycloartane triterpenes from Gardenia sootepensis - Wei-Wu Song; Xue-Qin Wang; Hua-Li Jia; Zheng-Kun Zhang; Yong-Jie Ding; Ya-Hong Chen (Natural Product Research, 2018)

Secondary metabolites from the Colletotrichum gloeosporioides A12, an endophytic fungus derived from Aquilaria sinensis - Hong-Xin Liu; Hai-Bo Tan; Yu-Chan Chen; Sai-Ni Li; Hao-Hua Li; Wei-Min Zhang (Natural Product Research, 2018)

Nitrogen additions reduce rhizospheric and heterotrophic respiration in a subtropical evergreen broad-leaved forest - Yong Peng; Guan-tao Chen; Shun Li; Hong-ling Hu; Ting-xing Hu; Li Liu; Yi Tang; Li-hua Tu (Plant and Soil, 2018)

Preference and performance of the two-spotted spider mite Tetranychus urticae (Acari: Tetranychidae) on strawberry cultivars - Ya-Jun Gong; Jin-Cui Chen; Liang Zhu; Li-Jun Cao; Gui-Hua Jin; Ary A. Hoffmann; Chuan-Fei Zhong; Peng Wang; George Lin; Shu-Jun Wei (Experimental and Applied Acarology, 2018)

Quantitative contribution of Cd2+ adsorption mechanisms by chicken-manure-derived biochars - Fei Huang; Li-Yang Gao; Jin-Huan Deng; Shao-Hua Chen; Kun-Zheng Cai (Environmental Science and Pollution Research, 2018)

A Dual-Replicon Shuttle Vector System for Heterologous Gene Expression in a Broad Range of Gram-Positive and Gram-Negative Bacteria - Mingxi Hua; Jingjing Guo; Min Li; Chen Chen; Yuanyuan Zhang; Chuan Song; Dong Jiang; Pengcheng Du; Hui Zeng (Current Microbiology, 2018)

Impact of atmospheric model resolution on simulation of ENSO feedback processes: a coupled model study - Lijuan Hua; Lin Chen; Xinyao Rong; Jingzhi Su; Lu Wang; Tim Li; Yongqiang Yu (Climate Dynamics, 2018)

Role of AGEs in the progression and regression of atherosclerotic plaques - Zhong-qun Wang; Le-le Jing; Jin-chuan Yan; Zhen Sun; Zheng-yang Bao; Chen Shao; Qi-wen Pang; Yue Geng; Li-li Zhang; Li-hua Li (Glycoconjugate Journal, 2018)

Associations of HSP90AA2 gene polymorphisms with disease susceptibility, glucocorticoids efficacy and health-related quality of life in Chinese systemic lupus erythematosus patients - Man Zhang; Su-Su Li; Qiao-Mei Xie; Jian-Hua Xu; Xiu-Xiu Sun; Fa-Ming Pan; Sheng-Qian Xu; Sheng-Xiu Liu; Jin-Hui Tao; Shuang Liu; Jing Cai; Pei-Ling Chen; et al. (Genes & Genomics, 2018)

Dependence of 3‐month Standardized Precipitation‐Evapotranspiration Index dryness/wetness sensitivity on climatological precipitation over southwest China - Shanlei Sun; Haishan Chen; Jinjian Li; Jiangfeng Wei; Guojie Wang; Ge Sun; Wenjian Hua; Shujia Zhou; Peng Deng (International Journal of Climatology, 2018)
In this study, we estimated the respective contributions of precipitation and reference evapotranspiration (ET 0 ) to annual SPEI‐3 (3‐month Standardized Precipitation‐Evapotranspiration Index) anomalies over southwest China (SWC) using numerical experiments. Results show that the dominant factor (i.e., precipitation or ET 0 ) for the dryness/wetness anomalies during 1961–2012 existed due to inter‐annual and inter‐decadal changes over SWC, which indicates the underlying mechanisms of dry/wet conditions have changed. On the other hand, we calculate the dryness/wetness sensitivity to precipitation or ET 0 (defined as changes in SPEI‐3 per millimetre) and find that the dryness/wetness sensitivity to ET 0 is higher than that to precipitation for the whole SWC and the overwhelming majority (99%) of the 269 sites. Overall, the above findings imply that the role of ET 0 in the dry/wet condition evolution is vital and should be paid more attentions. For the magnitude of the dryness/wetness sensitivity to precipitation or ET 0 , an evident increase from the southeast to northwest SWC is identified. Based on the analyses of the relationship between dryness/wetness sensitivity and climatological condition (i.e., precipitation, ET 0 , and aridity), the sensitivity magnitude is dependent on climatological precipitation and generally decreases with its increase. This study provides a wealth of quantitative information (e.g., dryness/wetness anomalies [sensitivity] caused by [to] precipitation and ET 0 ) for better understanding the underlying mechanisms of the dry/wet condition evolution.

Thimet oligopeptidase and prolyl endopeptidase of spotted scat Scatophagus argus: characterization, tissue distribution, expression at different ovarian stages and down-regulation by estradiol - Si-ping Deng; Dong-neng Jiang; Jian-ye Liu; Zhi-qi Liang; Hua-pu Chen; Tian-li Wu; Chun-hua Zhu; Guang-li Li (Fisheries Science, 2018)

An inversion of transient electromagnetic data from a conical source - Hai-Yan Yang; Feng-Ping Li; Shen-En Chen; Jian-Hua Yue; Fu-Sheng Guo; Xiao Chen; Hua Zhang (Applied Geophysics, 2018)

Chemical constituents from Curcuma longa L. and their inhibitory effects of nitric oxide production - Ting Yuan; Cuiyun Zhang; Chongyue Qiu; Guiyang Xia; Fei Wang; Bin Lin; Hua Li; Lixia Chen (Natural Product Research, 2018)

Intraspecific functional trait variability across different spatial scales: a case study of two dominant trees in Korean pine broadleaved forest - Tingting Li; Jian Wu; Hua Chen; Lanzhu Ji; Dapao Yu; Li Zhou; Wangming Zhou; Yuewei Tong; Yinghua Li; Limin Dai (Plant Ecology, 2018)

Neonatal Exposure to Low-Dose (1.2%) Sevoflurane Increases Rats’ Hippocampal Neurogenesis and Synaptic Plasticity in Later Life - Xi Chen; Xue Zhou; Lu Yang; Xu Miao; Di-Han Lu; Xiao-Yu Yang; Zhi-Bin Zhou; Wen-Bin Kang; Ke-Yu Chen; Li-Hua Zhou; Xia Feng (Neurotoxicity Research, 2018)

Regulation of myostatin expression is associated with growth and muscle development in commercial broiler and DMC muscle - Tengfei Dou; Zhengtian Li; Kun Wang; Lixian Liu; Hua Rong; Zhiqiang Xu; Ying Huang; Dahai Gu; Xiaobo Chen; Wenyuan Hu; Jiarong Zhang; Sumei Zhao; et al. (Molecular Biology Reports, 2018)