miR-23b Attenuates LPS-Induced Inflammatory Responses in Acute Lung Injury via Inhibition of HDAC2 - Zhi-Feng Luo; Xiang-Hui Jiang; Huan Liu; Li-Yuan He; Xiong Luo; Fu-Chun Chen; Yu-Lin Tan (Biochemical Genetics, 2021)

Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71 - Ya-Ping Li; Mu-Qi Wang; Chen-Rui Liu; Hui-Ling Deng; Yuan Wu; Shuang-Suo Dang; Li-Hong Xu (Archives of Virology, 2021)

Nocardioides acrostichi sp. nov., a novel endophytic actinobacterium isolated from leaf of Acrostichum aureum - Xiao-Hui Chen; Fei Li; Fei-Na Li; Ming-Sheng Chen; Xiao-Rui Yan; Zi-Bang He; Shun-Lian Li; You-Lang Wu; Li Tuo (Antonie van Leeuwenhoek, 2021)

Determination and risk assessment of perfluorinated alkylated substances (PFASs) in pork liver from mainland, China - Juan Zhang; Lu Qiao; Hui Li; Shuming Yang; Ailiang Chen (Food Additives & Contaminants: Part A, 2021)

Interest-activity symptom severity predicts response to ketamine infusion in treatment-resistant depression - Mu-Hong Chen; Wei-Chen Lin; Hui-Ju Wu; Ya-Mei Bai; Cheng-Ta Li; Shih-Jen Tsai; Chen-Jee Hong; Pei-Chi Tu; Tung-Ping Su (Psychopharmacology, 2021)

Unraveling Physiological and Metabolomic Responses Involved in Phlox subulata L. Tolerance to Drought Stress - Yan Xiong; Yanting Qu; Hui Han; Fei Chen; Li Li; Huanwei Tang; Daidi Che; Xing Zhang (Plant Molecular Biology Reporter, 2021)

Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling - Li Zhang; Lu Wang; Han Xiao; Hui Gan; Hui Chen; Shuyue Zheng; Dan Jian; Xuan Zhai; Ning Jiang; Zhao Jing; Ping Liang (Journal of Molecular Medicine, 2021)

High-Level Expression and Purification of Melittin in Escherichia coli Using SUMO Fusion Partner - Qiu-chi Chen; Lei Liu; Tian-Yi Yu; Lu Tang; Mo-li Yin; Wen-he Zhu; Xiu-yun Jiang; Hui-yan Wang (International Journal of Peptide Research and Therapeutics, 2021)

Efficient Editing of an Adenoviral Vector Genome with CRISPR/Cas9 - Qiang Li; Hui Wang; Chen-yu Gong; Zhao Chen; Jia-xing Yang; Hong-wei Shao; Wen-feng Zhang (Indian Journal of Microbiology, 2021)

Enhanced antioxidant capacity and upregulated transporter genes contribute to the UV-B-induced increase in blinin in Conyza blinii - Junyi Zhan; Qin Yang; Zhiyi Lin; Tianrun Zheng; Maojia Wang; Wenjun Sun; Tongliang Bu; Zizhong Tang; Chenglei Li; Xueyi Han; Haixia Zhao; Qi Wu; et al. (Environmental Science and Pollution Research, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Accumulation and Depuration of Cd and its Effect on the Expressions of Metallothionein and Apoptotic Genes in Litopenaeus vannamei - Ling Li; Yu-Chun Shen; Jin-Rong Liang; Hu Liu; Tian-Ci Chen; Hui Guo (Bulletin of Environmental Contamination and Toxicology, 2021)

Mechanism of pore water seepage in soil reinforced by step vacuum preloading - Wenchong Shan; Hui-e Chen; Xiaoqing Yuan; Wenliang Ma; Hui Li (Bulletin of Engineering Geology and the Environment, 2021)

Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease - Meng Zhang; Mengying Wang; Hui Wang; Ying Zhang; Zhengzheng Li; Yiping Feng; Yinan Liu; Yue Liu; Yucheng Liao; Wenjun Wang; Qian Fang; Jinghong Chen (Biological Trace Element Research, 2021)

Numerical study of scour depth effect on wave-induced seabed response and liquefaction around a pipeline - Hui Li; Shuqing Wang; Xuguang Chen; Cun Hu; Jinzhong Liu (Marine Georesources & Geotechnology, 2021)

QTL mapping for foxtail millet plant height in multi-environment using an ultra-high density bin map - Qiang He; Hui Zhi; Sha Tang; Lu Xing; Suying Wang; Haigang Wang; Aiying Zhang; Yuhui Li; Ming Gao; Haijin Zhang; Guoqiu Chen; Shutao Dai; et al. (Theoretical and Applied Genetics, 2021)

GmNAC06, a NAC domain transcription factor enhances salt stress tolerance in soybean - Ming Li; Rui Chen; Qiyan Jiang; Xianjun Sun; Hui Zhang; Zheng Hu (Plant Molecular Biology, 2021)
Key message We found GmNAC06 plays an important role in salt stress responses through the phenotypic, physiological and molecular analyses of OE, VC, and Mutant composite soybean. Abstract Salinization affects 20% of all cultivated land worldwide because of the high salinity of irrigation water and the excessive use of water, and this amount is increasing daily. NAC (NAM, ATAF, and CUC) have been found to be involved in salt stress. In this study, a soybean NAC gene, GmNAC06 (Glyma06g21020.1), was cloned and functionally characterized. The results of expression analysis suggested that salt stress could influence the expression level of GmNAC06 . The subcellular localization analysis results suggested that GmNAC06 may function as a transcription factor. Under salt stress, the overexpression technology combined with CRISPR-Cas9 system found that GmNAC06 could cause the accumulation of proline and glycine betaine to alleviate or avoid the negative effects of ROS; similarly, it could control the Na + /K + ratios in hairy roots to maintain ionic homeostasis. The fresh weight of the transgenic hairy roots and the histochemical ROS staining of wild leaves suggested that transgenic hairy roots influence the function of wild leaves under salt stress conditions. Moreover, the expression levels of GmUBC2 and GmHKT1 were higher in the GmNAC06 hairy roots than in the control. Thus, the overexpression of GmNAC06 in hairy roots notably causes an entire composite plant to exhibit salt tolerance. The phenotype of composite soybean plants and transgenic Arabidopsis plants suggest that GmNAC06 plays a role in response to salt stress and could be useful in generating salt tolerant transgenic crops.

Using Composite Phenotypes to Reveal Hidden Physiological Heterogeneity in High-Altitude Acclimatization in a Chinese Han Longitudinal Cohort - Yi Li; Yanyun Ma; Kun Wang; Menghan Zhang; Yi Wang; Xiaoyu Liu; Meng Hao; Xianhong Yin; Meng Liang; Hui Zhang; Xiaofeng Wang; Xingdong Chen; et al. (Phenomics, 2021)
Altitude acclimatization is a human physiological process of adjusting to the decreased oxygen availability. Since several physiological processes are involved and their correlations are complicated, the analyses of single traits are insufficient in revealing the complex mechanism of high-altitude acclimatization. In this study, we examined these physiological responses as the composite phenotypes that are represented by a linear combination of physiological traits. We developed a strategy that combines both spectral clustering and partial least squares path modeling (PLSPM) to define composite phenotypes based on a cohort study of 883 Chinese Han males. In addition, we captured 14 composite phenotypes from 28 physiological traits of high-altitude acclimatization. Using these composite phenotypes, we applied k-means clustering to reveal hidden population physiological heterogeneity in high-altitude acclimatization. Furthermore, we employed multivariate linear regression to systematically model (Models 1 and 2) oxygen saturation (SpO 2 ) changes in high-altitude acclimatization and evaluated model fitness performance. Composite phenotypes based on Model 2 fit better than single trait-based Model 1 in all measurement indices. This new strategy of using composite phenotypes may be potentially employed as a general strategy for complex traits research such as genetic loci discovery and analyses of phenomics.

LINC00173 promotes the apoptosis of hypertrophic scar fibroblasts through increasing β-catenin expression - Qian Li; Xin Chen; Ling Chen; Hui Yan; Jun Li (Molecular and Cellular Biochemistry, 2021)

Stability Control of the Equipment Recovery Passage in a Fully Mechanized Longwall Mining: Case Study - Zhiyi Zhang; Hui Chen; Dongfa Li; Zhiqiang Zhang (Geotechnical and Geological Engineering, 2021)

A coupled UV photolysis-biodegradation process for the treatment of decabrominated diphenyl ethers in an aerobic novel bioslurry reactor - Yi-Tang Chang; Huei-Chen Chen; Hsi-Ling Chou; Hui Li; Stephen A. Boyd (Environmental Science and Pollution Research, 2021)

Cerebral microbleeds and their influence on cognitive impairment in Dialysis patients - Yujun Qian; Ke Zheng; Haiyun Wang; Hui You; Fei Han; Jun Ni; Bo Hou; Limeng Chen; Yicheng Zhu; Feng Feng; Xuemei Li (Brain Imaging and Behavior, 2021)

A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization - Jinying Chen; Fan-Li Lin; Jacqueline Y. K. Leung; Leilei Tu; Jiang-Hui Wang; Yu-Fan Chuang; Fan Li; Hsin-Hui Shen; Gregory J. Dusting; Vickie H. Y. Wong; Leszek Lisowski; Alex W. Hewitt; et al. (Angiogenesis, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

The Effect of Composting on the Multiple Heavy Metals in the River Sediment Investigated by Multivariate Analysis - Yaoning Chen; Yanrong Chen; Yuanping Li; Yihuan Liu; Daoli Zhang; Yanxin Wu; Hui Li; Fangting Xu; Meiling Li (Water, Air, & Soil Pollution, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Partial recovery of disturbed V-J pairing profiles of T-cell receptor in people living with HIV receiving long-term antiretroviral therapy - Guoli Li; Jiarui Li; Henghui Zhang; Yu Zhang; Di Liu; Yu Hao; Junyan Han; Juan Du; Liuluan Zhu; Yongqin Zeng; Bei Li; Rui Li; et al. (Science China Life Sciences, 2021)

The Ocean Heat Content Changes in the South China Sea due to Tropical Cyclones with Different Tracks - Long Yu; Jia Sun; Zhenli Hui; Xuejun Xiong; Shanshan Jin; Lu Wang; Guangbing Yang; Yanliang Guo; Xia Ju; Liang Chen; Xiaomin Hu; Ying Li (Pure and Applied Geophysics, 2021)

A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice - Yuncheng Pan; Xi Yang; Feng Zhang; Siyuan Chen; Zixue Zhou; Hao Yin; Hui Ma; Lingyue Shang; Jialin Yang; Guoqing Li; Yingchen Wang; Li Jin; et al. (Molecular Genetics and Genomics, 2021)

A plant virus mediates interspecific competition between its insect vectors in Capsicuum annuum - Yong Chen; Xue Zheng; Hui Wei; Yong-Dui Chen; Kuan-Yu Zheng; Ye Mu; Xing-Yue Zhao; Li-Hua Zhao; Yu-Lin Gao; Li-Min Zheng; Jie Zhang (Journal of Pest Science, 2021)

A Fluorogenic and Chromogenic Probe Distinguishes Fluoride Anions and Thiols: Implications for Discrimination of Fluoride-Containing G Series and Sulfur-Containing V Series Nerve Agents - Wei-hui Wu; Xin Wang; Liang Zong; Dan Li; Yan-hua Xiao; Shao-hui Sui; Jian Li; Meng Liu; Gao-yun Chen; Teng Luo; Min Liu; Xin-ming Wang; et al. (Journal of Fluorescence, 2021)

Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice - Hehuan Lai; Tingting Nie; Yitong Zhang; Ying Chen; Jiaqi Tao; Tingting Lin; Tangdong Ge; Fenglan Li; Hui Li (Biological Trace Element Research, 2021)

From China’s Heavy Precipitation in 2020 to a “Glocal” Hydrometeorological Solution for Flood Risk Prediction - Huan Wu; Xiaomeng Li; Guy J.-P. Schumann; Lorenzo Alfieri; Yun Chen; Hui Xu; Zhifang Wu; Hong Lu; Yamin Hu; Qiang Zhu; Zhijun Huang; Weitian Chen; et al. (Advances in Atmospheric Sciences, 2021)

Observational study of super typhoon Meranti (2016) using satellite, surface drifter, Argo float and reanalysis data - Hui Chen; Shuang Li; Hailun He; Jinbao Song; Zheng Ling; Anzhou Cao; Zhongshui Zou; Wenli Qiao (Acta Oceanologica Sinica, 2021)

Chemical constituents from the South China sea soft coral Sinularia humilis - Jie Li; Xia-Juan Huan; Meng-Jun Wu; Zi-Hui Chen; Bao Chen; Ze-Hong Miao; Yue-Wei Guo; Xu-Wen Li (Natural Product Research, 2020)

Uncovering the mysterious identity of Taisui—an old Chinese folk legend - Erwei Li; Jinwei Ren; Qian Chen; Hanxing Zhang; Bin Lin; Hui Zhang; Shumin Zhang; Xiaoling Zhang; Lei Cai; Xingzhong Liu (Science China Life Sciences, 2020)

Genotype and Phenotype Correlations for TBL1XR1 in Neurodevelopmental Disorders - Yingting Quan; Qiumeng Zhang; Meilin Chen; Huidan Wu; Jianjun Ou; Yidong Shen; Kuokuo Li; Guanglei Xun; Jingping Zhao; Zhengmao Hu; Kun Xia; Hui Guo (Journal of Molecular Neuroscience, 2020)

The relationships of serum homocysteine levels and traditional lipid indicators with disease activity and coronary artery involvement in Takayasu arteritis - Si Chen; Haixia Luan; Jianxun He; Yan Wang; Xiaoli Zeng; Yongzhe Li; Hui Yuan (Immunologic Research, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Larger regional volume of the thalamus in diarrhea-predominant irritable bowel syndrome: a cross-sectional study - Cui Ping Mao; Fen Rong Chen; Hong Hong Sun; Mei Juan Shi; Hua Juan Yang; Xiao Hui Li; Dun Ding (Brain Imaging and Behavior, 2020)

Analyzing adaptation strategies for maize production under future climate change in Guanzhong Plain, China - Qaisar Saddique; Huanjie Cai; Jiatun Xu; Ali Ajaz; Jianqiang He; Qiang Yu; Yunfei Wang; Hui Chen; Muhammad Imran Khan; De Li Liu; Liang He (Mitigation and Adaptation Strategies for Global Change, 2020)

LncRNA NEAT1 accelerates renal mesangial cell injury via modulating the miR-146b/TRAF6/NF-κB axis in lupus nephritis - Li-Hua Zhang; Bin Xiao; Miao Zhong; Qiao Li; Jian-Ying Chen; Jie-Rou Huang; Hui Rao (Cell and Tissue Research, 2020)

Transcriptome analysis following enterovirus 71 and coxsackievirus A16 infection in respiratory epithelial cells - Jie Song; Yajie Hu; Weiyu Li; Hui Li; Huiwen Zheng; Yanli Chen; Shaozhong Dong; Longding Liu (Archives of Virology, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Solanrubiellin A, a hydroanthraquinone dimer with antibacterial and cytotoxic activity from Solanum lyratum - Hui Chen; Kun Du; Yan-Jun Sun; Zhi-You Hao; Yan-Li Zhang; Jiang Bai; Qing-Hua Wang; Hai-Yu Hu; Wei-Sheng Feng (Natural Product Research, 2020)

A practical method for employing multi-spectral LiDAR intensities in points cloud classification - Changhui Jiang; Yuwei Chen; Wenxin Tian; Haohao Wu; Wei Li; Hui Zhou; Hui Shao; Shaojing Song; Eetu Puttonen; Juha Hyyppä (International Journal of Remote Sensing, 2020)

Ferrous iron-induced increases in capitate glandular trichome density and upregulation of CbHO-1 contributes to increases in blinin content in Conyza blinii - Tianrun Zheng; Maojia Wang; Junyi Zhan; Wenjun Sun; Qin Yang; Zhiyi Lin; Tongliang Bu; Zizhong Tang; Chenglei Li; Jun Yan; Zhi Shan; Hui Chen (Planta, 2020)

Fasudil attenuates glial cell-mediated neuroinflammation via ERK1/2 and AKT signaling pathways after optic nerve crush - Wei Huang; Qianqian Lan; Li Jiang; Wenya Yan; Fen Tang; Chaolan Shen; Hui Huang; Haibin Zhong; Jian Lv; Siming Zeng; Min Li; Zhongxiang Mo; et al. (Molecular Biology Reports, 2020)

Circadian rhythm disorder: a potential inducer of vascular calcification? - Haoran Huang; Zhaohuai Li; Yuyi Ruan; Weijing Feng; Jie Chen; Xiaoxue Li; Liu Ouyang; Hui Huang (Journal of Physiology and Biochemistry, 2020)

Astragaloside protects rat brain from microwave-induced functional injuries via restoring acetylcholine and normalizing electroencephalogram - Li Zhao; Yunbo Sun; Chao Yu; Junjun Chen; Xinping Xu; Xueyan Zhang; Hui Wang; Jing Zhang; Haoyu Wang; Ji Dong; Binwei Yao; Hongmei Zhou; et al. (Environmental Science and Pollution Research, 2020)

Functional wastepaper-montmorillonite composite aerogel for Cd2+ adsorption - Yaoning Chen; Yihuan Liu; Yuanping Li; Li Zhao; Yanrong Chen; Hui Li; Yuqing Liu; Linshenzhang Li; Fangting Xu; Meiling Li (Environmental Science and Pollution Research, 2020)

Sulfur isotopic compositions of sulfides along the Southwest Indian Ridge: implications for mineralization in ultramafic rocks - Teng Ding; Chunhui Tao; Ágata Alveirinho Dias; Jin Liang; Jie Chen; Bin Wu; Dongsheng Ma; Rongqing Zhang; Jia Wang; Shili Liao; Yuan Wang; Weifang Yang; et al. (Mineralium Deposita, 2020)

A pair of new diastereoisomeric phenylpropanoid-substituted flavan from the leaves of Ilex centrochinensis - Hui Long; Yu Chen; Ze-Hua Hu; Shao-Jun Zhang; Lu-Jun Li (Natural Product Research, 2020)

Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis - Ning Xiao; Tian-long Liu; Hao Li; Hao-chen Xu; Jing Ge; Hong-yan Wen; Cong-xia Bai; Li Song; Ying-ying Sun; Yin-hui Zhang; Ru-tai Hui; Wei-hua Song; et al. (Translational Stroke Research, 2020)

Effects of arbuscular mycorrhizal fungi on redox homeostasis of rice under Cd stress - Hui Li; Xun Wen Chen; Li Wu; Na Luo; Wei Xiong Huang; Ce Hui Mo; Yan Wen Li; Lei Xiang; Hai Ming Zhao; Quan Ying Cai; Ming Hung Wong (Plant and Soil, 2020)

FtMYB18 acts as a negative regulator of anthocyanin/proanthocyanidin biosynthesis in Tartary buckwheat - Qixin Dong; Haixia Zhao; Yunji Huang; Ying Chen; Min Wan; Zixian Zeng; Panfeng Yao; Chenglei Li; Xiaoli Wang; Hui Chen; Qi Wu (Plant Molecular Biology, 2020)

Histidine kinase NME1 and NME2 are involved in TGF-β1-induced HSC activation and CCl4-induced liver fibrosis - Hui Gong; Zhiqiang Fan; Dan Yi; Junyu Chen; Zuojun Li; Ren Guo; Chunjiang Wang; Weijin Fang; Shikun Liu (Journal of Molecular Histology, 2020)

A LiDAR aiding ambiguity resolution method using fuzzy one-to-many feature matching - Chuang Qian; Hongjuan Zhang; Wenzhuo Li; Bao Shu; Jian Tang; Bijun Li; Zhijun Chen; Hui Liu (Journal of Geodesy, 2020)

Increased O-GlcNAcylation induces myocardial hypertrophy - Xiaoli Chen; Li Zhang; Hui He; Yikai Sun; Qin Shen; Linsheng Shi (In Vitro Cellular & Developmental Biology - Animal, 2020)

RNA-seq analysis reveals divergent adaptive response to hyper- and hypo-salinity in cobia, Rachycentron canadum - Danyu Cao; Jinfeng Li; Baosong Huang; Jiandong Zhang; Chuanhao Pan; Jiansheng Huang; Hui Zhou; Qian Ma; Gang Chen; Zhongliang Wang (Fish Physiology and Biochemistry, 2020)

Morphological and genetic characterisation of Centrorhynchus clitorideus (Meyer, 1931) (Acanthocephala: Centrorhynchidae) from the little owl Athene noctua (Scopoli) (Strigiformes: Strigidae) in Pakistan - Qing Zhao; Nehaz Muhammad; Hui-Xia Chen; Jun Ma; Suleman; Liang Li (Systematic Parasitology, 2020)

Molecular characterization of an emerging reassortant mammalian orthoreovirus in China - Dandan Ye; Zhaoyang Ji; Hongyan Shi; Jianfei Chen; Da Shi; Liyan Cao; Jianbo Liu; Mingwei Li; Hui Dong; Zhaoyang Jing; Xiaobo Wang; Qiuge Liu; et al. (Archives of Virology, 2020)

Characteristics of the spike and ORF3 genes of porcine epidemic diarrhea virus in Henan and Shanxi provinces of China - Jian-tao Cui; Han Qiao; Cheng-yao Hou; Hui-Hua Zheng; Xin-Sheng Li; Lan-lan Zheng; Hong-Ying Chen (Archives of Virology, 2020)

Depletion of florfenicol and florfenicol amine in eggs of laying hens and growing pullets after oral administration - Xia Li; Lu Chen; Hui Yue; Hua Feng; Enmin Xu; Xiuli Wei; Xiaoli Han; Ligang Deng; Zengmei Li (Food Additives & Contaminants: Part A, 2020)

Prevalence of Autism Spectrum Disorder in China: A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years - Hao Zhou; Xiu Xu; Weili Yan; Xiaobing Zou; Lijie Wu; Xuerong Luo; Tingyu Li; Yi Huang; Hongyan Guan; Xiang Chen; Meng Mao; Kun Xia; et al. (Neuroscience Bulletin, 2020)

NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy - Han Xiao; Hui Chen; Rong Jiang; Li Zhang; Lu Wang; Hui Gan; Ning Jiang; Jing Zhao; Xuan Zhai; Ping Liang (Journal of Molecular Medicine, 2020)

The protective effect of rosmarinic acid on myotube formation during myoblast differentiation under heat stress - Kun-Lin Chen; Yue Wang; Zhi-Ping Lin; Hui-Xia Li (In Vitro Cellular & Developmental Biology - Animal, 2020)

Characterization of Pneumocystis jirovecii pneumonia at three tertiary comprehensive hospitals in southern China - Yan-Hui Chen; Xue-Yao Fang; Yue-Ting Li; Yan-Ling Liu; Ya-Ping Hang; Yan-Ping Xiao; Xing-Wei Cao; Qiao-Shi Zhong; Long-Hua Hu (Brazilian Journal of Microbiology, 2020)

Rhodobacter xinxiangensis sp. nov., isolated from pakchoi-cultivated soil contaminated with heavy metal and its potential to reduce Cd and Pb accumulation in pakchoi (Brassica campestris L.) - Hui Han; Tiejun Wang; Zhaojin Chen; Yadong Li; Lunguang Yao (Archives of Microbiology, 2020)

A bacterial polysaccharide biosynthesis-related gene inversely regulates larval settlement and metamorphosis of Mytilus coruscus - Li-Hua Peng; Xiao Liang; Rui-Heng Chang; Jia-Yi Mu; Hui-E Chen; Asami Yoshida; Kiyoshi Osatomi; Jin-Long Yang (Biofouling, 2020)

Five new ent -kaurane diterpenes from Annona squamosa L. pericarps - Ya-Yun Chen; Cheng-Yao Ma; Mao-Lin Wang; Jia-Hui Lu; Peng Hu; Jian-Wei Chen; Xiang Li; Yong Chen (Natural Product Research, 2020)

Novel Magnetic Pomelo Peel Biochar for Enhancing Pb(II) And Cu(II) Adsorption: Performance and Mechanism - Yaoning Chen; Yihuan Liu; Yuanping Li; Yanrong Chen; Yanxin Wu; Hui Li; Sha Wang; Zhen Peng; Ran Xu; Ziping Zeng (Water, Air, & Soil Pollution, 2020)

Development of a daily soil moisture product for the period of 2002–2011 in Chinese mainland - Kun Yang; Yingying Chen; Jie He; Long Zhao; Hui Lu; Jun Qin; Donghai Zheng; Xin Li (Science China Earth Sciences, 2020)

Ablation of olfactory bulb glutamatergic neurons induces depressive-like behaviors and sleep disturbances in mice - Mao-Yun Yuan; Ze-Ka Chen; Jian Ni; Tian-Xiao Wang; Shi-Yu Jiang; Hui Dong; Wei-Min Qu; Zhi-Li Huang; Rui-Xi Li (Psychopharmacology, 2020)

Correction to: Deoxynivalenol-induced alterations in the redox status of HepG2 cells: identification of lipid hydroperoxides, the role of Nrf2-Keap1 signaling, and protective effects of zinc - Wageh Sobhy Darwish; Zhen Chen; Yonghan Li; Hui Tan; Hitoshi Chiba; Shu-Ping Hui (Mycotoxin Research, 2020)

RETRACTED ARTICLE: Deoxynivalenol-induced alterations in the redox status of HepG2 cells: identification of lipid hydroperoxides, the role of Nrf2-Keap1 signaling, and protective effects of zinc - Wageh Sobhy Darwish; Zhen Chen; Yonghan Li; Hui Tan; Hitoshi Chiba; Shu-Ping Hui (Mycotoxin Research, 2020)

Reconnaissance and learning after the February 6, 2018, earthquake in Hualien, Taiwan - Jui-Liang Lin; Chun-Hsiang Kuo; Yu-Wen Chang; Shu-Hsien Chao; Yi-An Li; Wen-Cheng Shen; Chung-Han Yu; Cho-Yen Yang; Fan-Ru Lin; Hsiao-Hui Hung; Chun-Chung Chen; Chin-Kuo Su; et al. (Bulletin of Earthquake Engineering, 2020)

Mesorhizobium rhizophilum sp. nov., a 1-aminocyclopropane-1-carboxylate deaminase producing bacterium isolated from rhizosphere of maize in Northeast China - Jun-lian Gao; Jing Xue; Yu-chen Sun; Han Xue; En Tao Wang; Hui Yan; Shuai Tong; Li-wei Wang; Xiuhai Zhang; Jian-guang Sun (Antonie van Leeuwenhoek, 2020)

Comparative transcriptome analysis reveals a gene expression profile that contributes to rhizome swelling in Panax japonicus var. major - Jun Rong Tang; Ying Chun Lu; Zheng Jie Gao; Wan Ling Song; Kun Hua Wei; Yan Zhao; Qing Yan Tang; Xue Jiao Li; Jun Wen Chen; Guang Hui Zhang; Guang Qiang Long; Wei Fan; et al. (Plant Biosystems, 2020)

New Terpenoids And Lignans From The Twigs Of T ripterygium Hypoglaucum - Hui Zheng; Li Wang; Tao Yang; Dan Liu; Hong-Mei Li; Xuan-Qin Chen; Rong-Tao Li (Natural Product Research, 2020)

Identification of QTLs for resistance to leaf spots in cultivated peanut (Arachis hypogaea L.) through GWAS analysis - Hui Zhang; Ye Chu; Phat Dang; Yueyi Tang; Tao Jiang; Josh Paul Clevenger; Peggy Ozias-Akins; Corley Holbrook; Ming Li Wang; Howard Campbell; Austin Hagan; Charles Chen (Theoretical and Applied Genetics, 2020)

Decreased sustained attention, processing speed and verbal learning memory in patients with insomnia in Chinese young and middle-aged adults: a cross-sectional study - Xie Chen; Cai-Lan Hou; Shi-Bin Wang; Zhuo-Hui Huang; Ying-Hua Huang; Xue-Li Li; Fu-Jun Jia (Sleep and Biological Rhythms, 2020)

Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort - Wei-Wei Li; Zhen Wang; Dong-Yu Fan; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Ling Li; Heng Yang; Yu-Hui Liu; Xian-Le Bu; Wang-Sheng Jin; Fan Zeng; et al. (Neuroscience Bulletin, 2020)

Hepatitis B virus X protein promotes liver cell pyroptosis under oxidative stress through NLRP3 inflammasome activation - Wen-hui Xie; Jian Ding; Xiao-xia Xie; Xiao-huang Yang; Xiao-Fan Wu; Zhi-xin Chen; Qi-lan Guo; Wen-yu Gao; Xiao-zhong Wang; Dan Li (Inflammation Research, 2020)
Objective Hepatitis B virus X protein (HBx) is a pivotal factor for HBV-induced hepatitis. Herein, we sought to investigate HBx-mediated NLR pyrin domain containing 3 (NLRP3) inflammasome activation and pyroptosis under oxidative stress. Methods The effect of HBx on the NLRP3 inflammasome was analyzed by enzyme-linked immunosorbent assays, quantitative reverse transcription-polymerase chain reaction, western blotting, and immunofluorescence in hepatic HL7702 cells. Pyroptosis was evaluated by western blotting, lactate dehydrogenase release, propidium iodide staining, and transmission electron microscopy. NLRP3 expression in the inflammasome from liver tissues was assessed by immunohistochemistry. Results In hydrogen peroxide (H 2 O 2 )-stimulated HL7702 cells, HBx triggered the release of pro-inflammatory mediators apoptosis-associated speck-like protein containing a CARD (ASC), interleukin (IL)-1β, IL-18, and high-mobility group box 1 (HMGB1); activated NLRP3; and initiated pro-inflammatory cell death (pyroptosis). HBx localized to the mitochondria, where it induced mitochondrial damage and production of mitochondrial reactive oxygen species (mitoROS). Treatment of HL7702 cells with a mitoROS scavenger attenuated HBx-induced NLRP3 activation and pyroptosis. Expression levels of NLRP3, ASC, and IL-1β in liver tissues from patients were positively correlated with HBV DNA concentration. Conclusions The NLRP3 inflammasome was activated by elevated mitoROS levels and mediated HBx-induced liver inflammation and hepatocellular pyroptosis under H 2 O 2 -stress conditions.

Dynamic behaviour and damage characteristics of loess in Xianyang, China - Huie Chen; Hui Li; Rui Fu; Xiaoqing Yuan (Bulletin of Engineering Geology and the Environment, 2020)

Crosstalk between PKC and MAPK pathway activation in cardiac fibroblasts in a rat model of atrial fibrillation - Wei-hua Guo; Xian Wang; Mei-sheng Shang; Zhe Chen; Qi Guo; Li Li; Hai-ying Wang; Rong-hui Yu; Chang-sheng Ma (Biotechnology Letters, 2020)

Miscanthus cultivation shapes rhizosphere microbial community structure and function as assessed by Illumina MiSeq sequencing combined with PICRUSt and FUNGUIld analyses - Yan Chen; Wei Tian; Yang Shao; Ying-Jun Li; Li-An Lin; Ying-Jun Zhang; Hui Han; Zhao-Jin Chen (Archives of Microbiology, 2020)

Analysis of virulence and immunogenic factors in Aeromonas hydrophila : Towards the development of live vaccines - Xian‐liang Zhao; Gan Wu; He Chen; Li Li; Xiang‐hui Kong (Journal of Fish Diseases, 2020)
Aeromonas hydrophila , a bacterium that is widespread in aquatic environments, is responsible for causing haemorrhagic disease in both aquatic and terrestrial species. With the purpose of developing a live vaccine, herein we have investigated nine strains of A. hydrophila (Ah‐01 to Ah‐09) isolated from diseased fish. A study of virulence factors that contribute to pathogenicity and immunogenicity in the host Cyprinus carpio suggests that the presence of β‐hly , act and fla genes contribute to pathogenesis: strains Ah‐01, Ah‐02 and Ah‐03 ( β‐hly + / act + / fla + genotype) were highly pathogenic to C. carpio , whereas Ah‐05 and Ah‐06 ( β‐hly − / act − / fla − genotype) showed weak pathogenicity. Accordingly, Ah‐02 and Ah‐03 were selected to prepare inactivated vaccines, whereas Ah‐05 and Ah‐06 were chosen as live vaccines. Ah‐06 live vaccine was found to have the best protective efficacy, with a protective rate of about 85%, whereas rates of other vaccines were significantly lower, in the range 37%–59%. In addition, DNA vaccines based on genes altA , aha and omp showed immune protection rates of 25%, 37.5% and 75%, respectively. Our data demonstrate that the β‐hly − / act − / fla − / altA + / aha + / omp + genotype has weak pathogenicity and high immunogenicity, and provide a simple and effective way to screen for live A. hydrophila vaccines.

Anti-hypertensive effects of Radix Rehmanniae and its active ingredients - Chiu-Haw Chao; Jue-Liang Hsu; Mu-Fen Chen; Ya-Hu Shih; Chia-Hui Lee; Mei-Li Wu; Chi-I Chang (Natural Product Research, 2020)

Whole-Brain Monosynaptic Inputs to Hypoglossal Motor Neurons in Mice - Han Guo; Xiang-Shan Yuan; Ji-Chuan Zhou; Hui Chen; Shan-Qun Li; Wei-Min Qu; Zhi-Li Huang (Neuroscience Bulletin, 2020)
Hypoglossal motor neurons (HMNs) innervate tongue muscles and play key roles in a variety of physiological functions, including swallowing, mastication, suckling, vocalization, and respiration. Dysfunction of HMNs is associated with several diseases, such as obstructive sleep apnea (OSA) and sudden infant death syndrome. OSA is a serious breathing disorder associated with the activity of HMNs during different sleep–wake states. Identifying the neural mechanisms by which the state-dependent activities of HMNs are controlled may be helpful in providing a theoretical basis for effective therapy for OSA. However, the presynaptic partners governing the activity of HMNs remain to be elucidated. In the present study, we used a cell-type-specific retrograde tracing system based on a modified rabies virus along with a Cre/loxP gene-expression strategy to map the whole-brain monosynaptic inputs to HMNs in mice. We identified 53 nuclei targeting HMNs from six brain regions: the amygdala, hypothalamus, midbrain, pons, medulla, and cerebellum. We discovered that GABAergic neurons in the central amygdaloid nucleus, as well as calretinin neurons in the parasubthalamic nucleus, sent monosynaptic projections to HMNs. In addition, HMNs received direct inputs from several regions associated with respiration, such as the pre-Botzinger complex, parabrachial nucleus, nucleus of the solitary tract, and hypothalamus. Some regions engaged in sleep–wake regulation (the parafacial zone, parabrachial nucleus, ventral medulla, sublaterodorsal tegmental nucleus, dorsal raphe nucleus, periaqueductal gray, and hypothalamus) also provided primary inputs to HMNs. These results contribute to further elucidating the neural circuits underlying disorders caused by the dysfunction of HMNs.

Simultaneous calcium recordings of hippocampal CA1 and primary motor cortex M1 and their relations to behavioral activities in freely moving epileptic mice - Xi Dong; Xin Zhang; Feifei Wang; Nannan Liu; Aili Liu; Yuanyuan Li; Liangpeng Wei; Feng Chen; Shiyang Yuan; Kai Zhang; Shaowei Hou; Qingyan Jiao; et al. (Experimental Brain Research, 2020)

Association between long-term exposure to Sulfur dioxide pollution and hypertension incidence in northern China: a 12-year cohort study - Mengfan Yan; Chaokang Li; Liwen Zhang; Xi Chen; Xueli Yang; Anqi Shan; Xuejun Li; Hui Wu; Zhao Ma; Yu Zhang; Pengyi Guo; Guanghui Dong; et al. (Environmental Science and Pollution Research, 2020)

Influence of wintertime surface sensible heat flux variability over the central and eastern Tibetan Plateau on the East Asian winter monsoon - Lian Chen; Renhe Zhang; Sara C. Pryor; Xiao Li; Hui Wang (Climate Dynamics, 2020)

Molecular evolution of GII.P17-GII.17 norovirus associated with sporadic acute gastroenteritis cases during 2013–2018 in Zhoushan Islands, China - Can Chen; Bing Wu; Hui Zhang; Ke-Feng Li; Rong Liu; Hong-Ling Wang; Jian-Bo Yan (Virus Genes, 2020)

N-Glycoproteome Reveals That N-Glycosylation Plays Crucial Roles in Photosynthesis and Carbon Metabolism in Young Rice Leaves - Jiafeng Wang; Hui Wen; Ming Li; Tao Guo; Chun Chen (Journal of Plant Biology, 2020)

HSV-1 infection and pathogenesis in the tree shrew eye following corneal inoculation - Lihong Li; Yan Li; Xin Li; Yujie Xia; Erlin Wang; Daohua Gong; Guijun Chen; Liping Yang; Ke Zhang; Zhuanghong Zhao; Nigel W. Fraser; Quanshui Fan; et al. (Journal of NeuroVirology, 2020)

Influence of Aphis gossypii feeding on defense strategy of native and introduced populations of Ageratina adenophora - Ying Lin; Shu-Qi He; Zhi-Hui Lu; Yu-Lin Gao; Yan-Ru Duan; Zheng-Yue Li; Bin Chen; Fu-Rong Gui (Arthropod-Plant Interactions, 2020)

Study on chemical constituents of an edible mushroom Volvariella volvacea and their antitumor activity in vitro - Ping Chen; Hui-Juan Qin; Yuan-Wei Li; Guo-Xu Ma; Jun-Shan Yang; Qi Wang (Natural Product Research, 2020)

Inhibitory effects of Dulcitol on rat C6 glioma by regulating autophagy pathway - Yuling Zhang; Hui Wang; Fangjuan Li; Xinxin Xu; Baogui Chen; Tao Zhang (Natural Product Research, 2020)

A new diterpenoid alkaloid from Aconitum hemsleyanum - Zhi-Hui Luo; Yang Chen; Xin-Yi Sun; Hua Fan; Wei Li; Liang Deng; Tian-Peng Yin (Natural Product Research, 2020)

Identification and characterization of two morphologically distinct stem cell subpopulations from human urine samples - An-Jing Chen; Jin-Kui Pi; Jun-Gen Hu; Yi-Zhou Huang; Hong-Wei Gao; Sheng-Fu Li; Jesse Li-Ling; Hui-Qi Xie (Science China Life Sciences, 2020)

Multiple omics analysis of the protective effects of SFN on estrogen-dependent breast cancer cells - Hui Huang; Shuyuan Cao; Zhan Zhang; Lei Li; Feng Chen; Qian Wu (Molecular Biology Reports, 2020)

Expression of long pentraxin 3 in human nasal mucosa fibroblasts, tissues, and secretions of chronic rhinosinusitis without nasal polyps - Yih-Jeng Tsai; Chung-Yu Hao; Chih-Li Chen; Pi-Hui Wu; Wen-Bin Wu (Journal of Molecular Medicine, 2020)

Numerical simulation investigations into the influence of the mass ratio of pulverized-coal in fuel-rich flow to that in fuel-lean flow on the combustion and NOx generation characteristics of a 600-MW down-fired boiler - Xiaoguang Li; Lingyan Zeng; Hongye Liu; Minhang Song; Wenjie Liu; Hui Han; Shaofeng Zhang; Zhichao Chen; Zhengqi Li (Environmental Science and Pollution Research, 2020)

Correction to: The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats - Yahong Liu; Hui Chen; Li Zhang; Tao Zhang; Xuan Ren (Biological Trace Element Research, 2020)

The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats - Yahong Liu; Hui Chen; Li Zhang; Tao Zhang; Xuan Ren (Biological Trace Element Research, 2020)

Illumina MiSeq sequencing and network analysis the distribution and co-occurrence of bacterioplankton in Danjiangkou Reservoir, China - Zhao-Jin Chen; Ge Xu; Chuan-Yu Ding; Bao-Hai Zheng; Yan Chen; Hui Han; Yu-Ying Li; Jian-Wei Shi; Lan-Qun Hu (Archives of Microbiology, 2020)

PX Domain-Containing Kinesin KIF16B and Microtubule-Dependent Intracellular Movements - Bo-jie Li; Hao Chen; Su-su Jiang; Chu-yao Wang; Qin-hui Tuo; Shi-yin Long; Cai-ping Zhang; Duan-fang Liao (The Journal of Membrane Biology, 2020)

Serum Uric Acid Levels and Risk of Intracranial Atherosclerotic Stenosis: A Cross-Sectional Study - Lin Li; Jun-Xia Zhu; Xiao-He Hou; Ya-Hui Ma; Wei Xu; Chen-Chen Tan; Fu-Rong Sun; Hong-Qi Li; Qiang Dong; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2020)

Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hippocampus of Epileptic Rats - Pan Gu; Zi-Hao Xu; Yu-Ze Cao; Sheng-Hui Liao; Qian-Fang Deng; Xian-Zhen Yin; Zhuo-Lu Wang; Zhuo-Hui Chen; Xin-Hang Hu; Hui Wang; Li-Zhi Li; Shi-Xin Liu; et al. (Neuroscience Bulletin, 2020)

Brain-Wide Shape Reconstruction of a Traced Neuron Using the Convex Image Segmentation Method - Shiwei Li; Tingwei Quan; Hang Zhou; Qing Huang; Tao Guan; Yijun Chen; Cheng Xu; Hongtao Kang; Anan Li; Ling Fu; Qingming Luo; Hui Gong; et al. (Neuroinformatics, 2020)

Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells - Kun-Lin Chen; Hui-Li Wang; Lin-Zheng Jiang; Yong Qian; Cai-Xia Yang; Wei-Wei Chang; Ji-Feng Zhong; Guang-Dong Xing (In Vitro Cellular & Developmental Biology - Animal, 2020)

Toxicological responses, bioaccumulation, and metabolic fate of triclosan in Chlamydomonas reinhardtii - Xiao Dong Wang; Yi Chen Lu; Xiao Hui Xiong; Yi Yuan; Li Xia Lu; Yuan Jian Liu; Jia Hao Mao; Wei Wei Xiao (Environmental Science and Pollution Research, 2020)

Human umbilical cord mesenchymal stem cell exosomes alleviate sepsis-associated acute kidney injury via regulating microRNA-146b expression - Rongxue Zhang; Yuan Zhu; Yang Li; Wanzhu Liu; Lei Yin; Siqi Yin; Cheng Ji; Yuyan Hu; Qiongni Wang; Xinru Zhou; Jingyan Chen; Wenrong Xu; et al. (Biotechnology Letters, 2020)

Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice - Ying Wang; Chao Yin; Zhidan Chen; Yang Li; Yan Zou; Xiang Wang; Yanpeng An; Feizhen Wu; Guoping Zhang; Chunjie Yang; Huiru Tang; Yunzeng Zou; et al. (Cell and Tissue Research, 2020)

Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission - Xintian Xu; Ping Chen; Jingfang Wang; Jiannan Feng; Hui Zhou; Xuan Li; Wu Zhong; Pei Hao (Science China Life Sciences, 2020)

Nanodosimetric understanding to the dependence of the relationship between dose-averaged lineal energy on nanoscale and LET on ion species - Tianyuan Dai; Hui Zhang; Xinguo Liu; Zhongying Dai; Pengbo He; Yuanyuan Ma; Guosheng Shen; Weiqiang Chen; Qiang Li (Physical and Engineering Sciences in Medicine, 2020)

Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity - Yujia Li; Hui Chen; Yating Yang; Menglan Niu; Jiaxin Wang; Yuanyuan Wu; Linhui Niu; Hongliang Liu; Dengke Bao (Journal of Natural Medicines, 2020)

Potential Genes Related to Levofloxacin Resistance in Mycobacterium tuberculosis Based on Transcriptome and Methylome Overlap Analysis - Hai-cheng Li; Hui-xin Guo; Tao Chen; Wei Wang; Zhu-hua Wu; Liang Chen; Hui-zhong Wu; Gao-po Xu; Xun-xun Chen; Lin Zhou (Journal of Molecular Evolution, 2020)
Drug-resistant Mycobacterium tuberculosis ( M. tuberculosis ) has become an increasingly serious public health problem and has complicated tuberculosis (TB) treatment. Levofloxacin (LOF) is an ideal anti-tuberculosis drug in clinical applications. However, the detailed molecular mechanisms of LOF-resistant M. tuberculosis in TB treatment have not been revealed. Our study performed transcriptome and methylome sequencing to investigate the potential biological characteristics of LOF resistance in M. tuberculosis H37Rv. In the transcriptome analysis, 953 differentially expressed genes (DEGs) were identified; 514 and 439 DEGs were significantly downregulated and upregulated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 97 pathways were enriched in this study. In the methylome analysis, 239 differentially methylated genes (DMGs) were identified; 150 and 89 DMGs were hypomethylated and hypermethylated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 74 pathways were enriched in this study. The overlap study suggested that 25 genes were obtained. It was notable that nine genes expressed downregulated mRNA and upregulated methylated levels, including pgi , fadE4 , php , cyp132 , pckA , rpmB1 , pfkB , acg , and ctpF , especially cyp132 , pckA , and pfkB , which were vital in LOF-resistant M. tuberculosis H37Rv. The overlapping genes between transcriptome and methylome could be essential for studying the molecular mechanisms of LOF-resistant M. tuberculosis H37Rv. These results may provide informative evidence for TB treatment with LOF.

Landslide mapping with remote sensing: challenges and opportunities - Cheng Zhong; Yue Liu; Peng Gao; Wenlong Chen; Hui Li; Yong Hou; Tuohuti Nuremanguli; Haijian Ma (International Journal of Remote Sensing, 2020)

Detection of Small Ship Objects Using Anchor Boxes Cluster and Feature Pyramid Network Model for SAR Imagery - Peng Chen; Ying Li; Hui Zhou; Bingxin Liu; Peng Liu (Journal of Marine Science and Engineering, 2020)
The synthetic aperture radar (SAR) has a special ability to detect objects in any climate and weather conditions. Consequently, SAR images are widely used in maritime transportation safety and fishery law enforcement for maritime object detection. Currently, deep-learning models are being extensively used for the detection of objects from images. Among them, the feature pyramid network (FPN) uses pyramids for representing semantic information regardless of the scale and has an improved accuracy of object detection. It is also suitable for the detection of multiple small ship objects in SAR images. This study aims to resolve the problems associated with small-object and multi-object ship detection in complex scenarios e.g., when a ship nears the port, by proposing a detection method based on an optimized FPN model. The feature pyramid model is first embedded in a traditional region proposal network (RPN) and mapped into a new feature space for object identification. Subsequently, the k-means clustering algorithm based on the shape similar distance (SSD) measure is used to optimize the FPN. Initial anchor boxes and tests are created using the SAR ship dataset. Experimental results show that the proposed algorithm for object detection shows an accuracy of 98.62%. Compared with Yolo, the RPN based on VGG/ResNet, FPN based on VGG/ResNet, and other models in complex scenarios, the proposed model shows a higher accuracy rate and better overall performance.

Phylogeography and population dynamics of an endemic oak (Quercus fabri Hance) in subtropical China revealed by molecular data and ecological niche modeling - Xiao-Dan Chen; Jia Yang; Li Feng; Tao Zhou; Hao Zhang; Hui-Min Li; Guo-Qing Bai; Xu Meng; Zhong-Hu Li; Gui-Fang Zhao (Tree Genetics & Genomes, 2020)

The expression and role of PIDD in retina after optic nerve crush - Fen Tang; Fan Xu; Ling Cui; Wei Huang; Li Jiang; Lifei Chen; Wenya Yan; Wenjing He; Chaolan Shen; Hui Huang; Jian Lv; Xin Zhao; et al. (Journal of Molecular Histology, 2020)

Optimizing the frequency ratio method for landslide susceptibility assessment: A case study of the Caiyuan Basin in the southeast mountainous area of China - Yi-xing Zhang; Heng-xing Lan; Lang-ping Li; Yu-ming Wu; Jun-hui Chen; Nai-man Tian (Journal of Mountain Science, 2020)

Fast Double Selectivity Index-CFAR Detection Method for the Multi-Beam Echo Sounder - Jiaqi Wang; Haisen Li; Jingxin Ma; Baowei Chen; Tianyao Xing; Hui Zhao (Marine Geodesy, 2020)

The Arabidopsis kinase-associated protein phosphatase KAPP, interacting with protein kinases SnRK2.2/2.3/2.6, negatively regulates abscisic acid signaling - Kai Lu; Ya-Dong Zhang; Chun-Fang Zhao; Li-Hui Zhou; Qing-Yong Zhao; Tao Chen; Cai-Lin Wang (Plant Molecular Biology, 2020)

Methamphetamine-Induced Cognitive Deficits and Psychiatric Symptoms Are Associated with Serum Markers of Liver Damage - Tingting Zhao; Changping Zhai; Hongmei Song; Yanhai Wu; Chuanhui Ge; Yonglin Zhang; Hongxia Xu; Zhengsuo Chi; Hui Chu; Wei Shi; Xiaodong Cheng; Xin Li; et al. (Neurotoxicity Research, 2020)

Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression - Fang Yang; Wang-wang Liu; Hui Chen; Jia Zhu; Ai-hua Huang; Fei Zhou; Yi Gan; Yan-hua Zhang; Li Ma (Journal of Zhejiang University-SCIENCE B, 2020)

Modified stepwise mini-incision microdissection testicular sperm extraction: a useful technique for patients with a history of orchidopexy affected by non-obstructive azoospermia - Peng Li; Chen-cheng Yao; Er-lei Zhi; Yuan Xu; Zhong Wan; Ying-chuan Jiang; Yu-hua Huang; Yue-hua Gong; Hui-xing Chen; Ru-hui Tian; Chao Yang; Liang-yu Zhao; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Identification of cadmium-produced lipid hydroperoxides, transcriptomic changes in antioxidant enzymes, xenobiotic transporters, and pro-inflammatory markers in human breast cancer cells (MCF7) and protection with fat-soluble vitamins - Wageh Sobhy Darwish; Zhen Chen; Yonghan Li; Yue Wu; Hitoshi Chiba; Shu-Ping Hui (Environmental Science and Pollution Research, 2020)

Silicon isotope composition of subduction zone fluids as recorded by jadeitites from Myanmar - An-Xia Chen; Yuan-Hong Li; Yi Chen; Hui-Min Yu; Fang Huang (Contributions to Mineralogy and Petrology, 2020)

Wave and current-induced dynamic response in a multilayered poroelastic seabed - Hui-Feng Qi; Zhang-Long Chen; Yi-Cheng Li; Shi-Jin Feng; Hong-Xin Chen (Bulletin of Engineering Geology and the Environment, 2020)

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages - Di Chen; Xiang-Yu Xu; Rui Li; Gen-Ao Zang; Yue Zhang; Ming-Rui Wang; Meng-Fei Xiong; Jia-Rui Xu; Ting Wang; Hui Fu; Qin Hu; Bin Wu; et al. (AAPS PharmSciTech, 2020)

Transcriptome Profile Analysis of Twisted Leaf Disease Response in Susceptible Sugarcane with Narenga porphyrocoma Genetic Background - Jinju Wei; Zhihui Xiu; Huiping Ou; Junhui Chen; Huayan Jiang; Xiaoqiu Zhang; Ronghua Zhang; Hui Zhou; Yiyun Gui; Haibi Li; Yangrui Li; Rongzhong Yang; et al. (Tropical Plant Biology, 2019)

Effects of Exogenous GA3 and DPC Treatments on Levels of Endogenous Hormone and Expression of Key Gibberellin Biosynthesis Pathway Genes During Stem Elongation in Sugarcane - Li-Hang Qiu; Rong-Fa Chen; Han-Min Luo; Ye-Geng Fan; Xing Huang; Jun-Xian Liu; Fa-Qian Xiong; Hui-Wen Zhou; Chong-Kun Gan; Jian-Ming Wu; Yang-Rui Li (Sugar Tech, 2019)

Collagen-binding basic fibroblast growth factor improves functional remodeling of scarred endometrium in uterine infertile women: a pilot study - Peipei Jiang; Xiaoqiu Tang; Huiyan Wang; Chenyan Dai; Jing Su; Hui Zhu; Minmin Song; Jingyu Liu; Ziqing Nan; Tong Ru; Yaling Li; Jingmei Wang; et al. (Science China Life Sciences, 2019)

Localization of Mucin 1 in endometrial luminal epithelium and its expression in women with reproductive failure during implantation window - Fangrong Wu; Di Mao; Yingyu Liu; Xiaoyan Chen; Hui Xu; Tin Chiu Li; Chi Chiu Wang (Journal of Molecular Histology, 2019)

Paramyxoviruses respiratory syncytial virus, parainfluenza virus, and human metapneumovirus infection in pediatric hospitalized patients and climate correlation in a subtropical region of southern China: a 7-year survey - Wen-Kuan Liu; De-Hui Chen; Wei-Ping Tan; Shu-Yan Qiu; Duo Xu; Li Zhang; Shu-Jun Gu; Rong Zhou; Qian Liu (European Journal of Clinical Microbiology & Infectious Diseases, 2019)

Short hairpin RNAs targeting M and N genes reduce replication of porcine deltacoronavirus in ST cells - Wen-yuan Gu; Yan Li; Bao-jing Liu; Jing Wang; Guang-fu Yuan; Shao-jie Chen; Yu-Zhu Zuo; Jing-Hui Fan (Virus Genes, 2019)

The complete chloroplast genome of the daimyo oak, Quercus dentata Thunb. - Hua-Lei Hu; Jing-Yu Zhang; Yu-Ping Li; Lu Xie; Dong-Bin Chen; Qun Li; Yan-Qun Liu; Shu-Rong Hui; Li Qin (Conservation Genetics Resources, 2019)

Development and characterization of 29 SNP markers for the Tibetan macaque (Macaca thibetana) - Xinshang Zhang; Lihong Niu; Liang Zhou; Zhifeng Yan; Fan Yang; Aiming Wu; Shaokun Min; Xiao Li; Kaishan Tao; Kefeng Dou; Hui Chen (Conservation Genetics Resources, 2019)

Effects of Chronic Voluntary Alcohol Drinking on Thiamine Concentrations, Endoplasmic Reticulum Stress, and Oxidative Stress in the Brain of Crossed High Alcohol Preferring Mice - Hong Xu; Dexiang Liu; Jing Chen; Hui Li; Mei Xu; Wen Wen; Jacqueline A. Frank; Nicholas J. Grahame; Haining Zhu; Jia Luo (Neurotoxicity Research, 2019)

Two episodes of REE mineralization in the Qinling Orogenic Belt, Central China: in-situ U-Th-Pb dating of bastnäsite and monazite - Wei Zhang; Wei Terry Chen; Jian-Feng Gao; Hua-Kai Chen; Jing-Hui Li (Mineralium Deposita, 2019)

Accumulation and Depuration of Nonylphenol and Its Effect on the Expressions of Vitellogenin and Vitellogenin Receptor in Freshwater Prawn Macrobrachium rosenbergii - Hui Guo; Luan-luan Chen; Guang-li Li; Si-ping Deng; Chun-hua Zhu (Bulletin of Environmental Contamination and Toxicology, 2019)

A loop-mediated isothermal amplification assay can rapidly diagnose soybean root-rot and damping-off diseases caused by Pythium spinosum - Hui Feng; Jiajia Chen; Ze Yu; Zhe Li; Wenwu Ye; Yuanchao Wang; Xiaobo Zheng (Australasian Plant Pathology, 2019)

Three new labdane-type diterpenoids from Callicarpa macrophylla Vahl. - Zhen-Hui Wang; Huan-Jun Xu; Yang-Yang Zhai; Lan-Ping Yang; Qiang Li; Mei Huang; Xing-Ying Chen; Wen-Kui Zhang; Yue-Li Meng; Qing-Ling Zhang; Chao Niu; Yan-Ru Zhang (Natural Product Research, 2019)

From Analysis of Ischemic Mouse Brain Proteome to Identification of Human Serum Clusterin as a Potential Biomarker for Severity of Acute Ischemic Stroke - Hailong Song; Hui Zhou; Zhe Qu; Jie Hou; Weilong Chen; Weiwu Cai; Qiong Cheng; Dennis Y. Chuang; Shanyan Chen; Shuwei Li; Jilong Li; Jianlin Cheng; et al. (Translational Stroke Research, 2019)

A specific assay for JmjC domain-containing lysine demethylase and its application to inhibitor screening - He Wen; Guo Li; Yongcan Chen; Meiting Li; Yafei Lv; Zhiming Li; Yinglu Li; Tianyun Hou; Hui Wang; Chaohua Liu; Xiaopeng Lu; Qian Zhu; et al. (Science China Life Sciences, 2019)

Refined chronology of prehistoric cultures and its implication for re-evaluating human-environment relations in the Hexi Corridor, northwest China - Yishi Yang; Shanjia Zhang; Chris Oldknow; Menghan Qiu; Tingting Chen; Haiming Li; Yifu Cui; Lele Ren; Guoke Chen; Hui Wang; Guanghui Dong (Science China Earth Sciences, 2019)

Two-factor ANOVA of SSH and RNA-seq analysis reveal development-associated Pi-starvation genes in oilseed rape - Zhong-Wei Zhang; Ling-Yang Feng; Jian-Hui Wang; Yu-Fan Fu; Xin Cai; Chang-Quan Wang; Jun-Bo Du; Ming Yuan; Yang-Er Chen; Pei-Zhou Xu; Ting Lan; Guang-Deng Chen; et al. (Planta, 2019)

Genetic Association Between NGFR, ADAM17 Gene Polymorphism, and Parkinson’s Disease in the Chinese Han Population - Wei-Wei Li; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Qian-Qian Shi; Jing Mei; Heng Yang; Fa-Ying Zhou; An-Yu Shi; Tao Zhang; Xiu-Qing Yao; Zhi-Qiang Xu; et al. (Neurotoxicity Research, 2019)

Immunological microenvironment alterations in follicles of women with proven severe endometriosis undergoing in vitro fertilization - Xiao-Dan Mao; Chen-Yu Hu; Meng-Chu Zhu; Hui-Lin Ou; Yu-Li Qian (Molecular Biology Reports, 2019)

Ginsenoside compound K ameliorates Alzheimer’s disease in HT22 cells by adjusting energy metabolism - Xijun Chen; Hui Li; Qing Yang; Xingcheng Lan; Jifeng Wang; Zhanhong Cao; Xiaozheng Shi; Jing Li; Mo Kan; Xiaobo Qu; Na Li (Molecular Biology Reports, 2019)

Trace metals in aquatic environments of a mangrove ecosystem in Nansha, Guangzhou, South China: pollution status, sources, and ecological risk assessment - Yingjie Chen; Huanfang Huang; Yang Ding; Wenwen Chen; Jie Luo; Hui Li; Jian Wu; Wei Chen; Shihua Qi (Environmental Monitoring and Assessment, 2019)

The mechanism of damage in the midgut of Bombyx mori after chlorantraniliprole exposure - Jiahuan Hu; Mengxue Li; Zhengting Lu; Tingting Mao; Jian Chen; Hui Wang; Jianwei Qu; Yilong Fang; Xiaoyu Cheng; Jinxin Li; Fanchi Li; Bing Li (Ecotoxicology, 2019)

ATP induces caspase-3/gasdermin E-mediated pyroptosis in NLRP3 pathway-blocked murine macrophages - Chen-Ying Zeng; Chen-Guang Li; Jun-Xiang Shu; Li-Hui Xu; Dong-Yun Ouyang; Feng-Yi Mai; Qiong-Zhen Zeng; Cheng-Cheng Zhang; Rui-Man Li; Xian-Hui He (Apoptosis, 2019)

Antihyperlipidemic glycosides from the root bark of Lycium chinense - Hui Chen; Yu-Jie Li; Yan-Jun Sun; Xiao-Kun Li; Gong Jian-Hong; Ya Wu; Fang-Yi Su; Kun Du; Yan-Li Zhang; Wei-Sheng Feng (Natural Product Research, 2019)

Accumulation of Pore Pressure in a Soft Clay Seabed around a Suction Anchor Subjected to Cyclic Loads - Hui Li; Xuguang Chen; Cun Hu; Shuqing Wang; Jinzhong Liu (Journal of Marine Science and Engineering, 2019)
A suction anchor is an appealing anchoring solution for floating production. However, the possible effects of residual pore pressure can be rarely found any report so far in term of the research and design. In this study, the residual pore pressure distribution characteristics around the suction anchor subjected to vertical cyclic loads are investigated in a soft clay seabed, and a three-dimensional damage-dependent bounding surface model is also proposed. This model adopts the combined isotropic-kinematic hardening rule to achieve isotropic hardening and kinematic hardening of the boundary surface. The proposed model is validated against triaxial tests on anisotropically consolidated saturated clays and normally consolidated saturated clays. The analytical results show that the excess pore water pressure accumulates primarily on the outside of the suction anchor, whereas negative pore water pressure mainly on the inside. The maximum values of both sides appear in the lower part of the seabed. According to the distribution characteristics of the residual pore pressure, a perforated anchor is proposed to reduce the accumulation of excess pore water pressure. A comparative study generally shows that the perforated anchor can effectively reduce the accumulation of excess pore water pressure.

MdHIR4 transcription and translation levels associated with disease in apple are regulated by MdWRKY31 - Xian-Yan Zhao; Chen-Hui Qi; Han Jiang; Ming-Shuang Zhong; Chun-Xiang You; Yuan-Yuan Li; Yu-Jin Hao (Plant Molecular Biology, 2019)

Functional Identification of Apple MdGLK1 Which Regulates Chlorophyll Biosynthesis in Arabidopsis - Xiu-Hong An; Yi Tian; Yan-Hui Chen; En-Mao Li; Min Li; Cun-Gang Cheng (Journal of Plant Growth Regulation, 2019)

Effects of Mn(II) on the Oxidation of Fe in Soils and the Uptake of Cadmium by Rice (Oryza sativa) - Hong Chen; Jing Lei; Hui Tong; Minghua Gu; Yuan Fang; Xueli Wang; Cuirong Tang; Zhiming Li; Chengshuai Liu (Water, Air, & Soil Pollution, 2019)

Improved partial trend method to detect rainfall trends in Hainan Island - Hao Wu; Xinyan Li; Hui Qian; Jie Chen (Theoretical and Applied Climatology, 2019)

Estrogen modulation of visceral pain - Li-hong Sun; Wen-xin Zhang; Qi Xu; Hui Wu; Cui-cui Jiao; Xin-zhong Chen (Journal of Zhejiang University-SCIENCE B, 2019)

Tamarixetin protects against cardiac hypertrophy via inhibiting NFAT and AKT pathway - Cheng Fan; Yuan Li; Hui Yang; Yuqian Cui; Hao Wang; Heng Zhou; Jianning Zhang; Binfeng Du; Qian Zhai; Dawei Wu; Xiaomei Chen; Haipeng Guo (Journal of Molecular Histology, 2019)

Distribution, source, and environmental risk assessment of phthalate esters (PAEs) in water, suspended particulate matter, and sediment of a typical Yangtze River Delta City, China - Hui Chen; Wei Mao; Yiqiu Shen; Weiwei Feng; Guanghua Mao; Ting Zhao; Lanqin Yang; Liuqing Yang; Chunfeng Meng; Yong Li; Xiangyang Wu (Environmental Science and Pollution Research, 2019)

U13 → C13 mutation in the variable region of the NA gene 3′UTR of H9N2 influenza virus influences the replication and transcription of NA and enhances virus infectivity - Xi Li; Yanci Chen; Xin Wang; Bo Peng; Weihua Wu; Hui Liu; Ying Sun; Xiujuan Tang; Qing Zheng; Shisong Fang (Virus Genes, 2019)

Dynamic expressions of hypothalamic genes regulate seasonal breeding in a natural rodent population - Dawei Wang; Ning Li; Lin Tian; Fei Ren; Zhengguang Li; Yan Chen; Lan Liu; Xiangfa Hu; Xuechang Zhang; Ying Song; Roelof A. Hut; Xiao‐Hui Liu (Molecular Ecology, 2019)
Seasonal breeding is a universal reproductive strategy in many animals. Hypothalamic genes, especially type 2 and 3 iodothyronine deiodinases ( Dio2 / 3 ), RFamide‐related peptide 3 ( Rfrp‐3 ), kisspeptin ( Kiss‐1 ) and gonadotropin‐releasing hormone ( GnRH ), are involved in a photoperiodic pathway that encodes seasonal signals from day length in many vertebrate species. However, the seasonal expression patterns of these genes in wild mammals are less studied. Here, we present a four‐year field investigation to reveal seasonal rhythm and age‐dependent reproductive activity in male Brandt's voles ( Lasiopodomys brandtii ) and to detect relationships among seasonal expression profiles of hypothalamic genes, testicular activity, age and annual day length. From breeding season (April) to nonbreeding season (October), adult male voles displayed a synchronous peak in gonadal activity with annual day length around summer solstice, which was jointly caused by age structure shifts and age‐dependent gonadal development patterns. Overwintered males maintained reproductive activity until late in the breeding season, whereas most newborn males terminated gonadal development completely, except for a minority of males born early in spring. Consistently, the synchronous and opposite expression profiles of Dio2/3 suggest their central function to decode photoperiodic signals and to predict the onset of the nonbreeding season. Moreover, changes in Dio2/3 signals may guide the actions of Kiss‐1 and Rfrp‐3 to regulate the age‐dependent divergence of reproductive strategy in wild Brandt's vole. Our results provide evidence on how hypothalamic photoperiod genes regulate seasonal breeding in a natural rodent population.

Skipping of an exon with a nonsense mutation in the DMD gene is induced by the conversion of a splicing enhancer to a splicing silencer - Yanrong Zhu; Huiting Deng; Xiangfa Chen; Hui Li; Cheng Yang; Shuo Li; Xiaoying Pan; Siqi Tian; Shuxin Feng; Xiaoyue Tan; Masafumi Matsuo; Zhujun Zhang (Human Genetics, 2019)

Structural characterisation and ACE-inhibitory activities of polysaccharide from Gastrodia elata Blume - Zhen-Yuan Zhu; Chun-Juan Chen; Hui-Qing Sun; Li-Jing Chen (Natural Product Research, 2019)

Structural properties and antioxidant activities of polysaccharide from fruit bodies of Pholiota nameko - Zhen-Yuan Zhu; Li-Chao Pan; Dan Han; Hui-qing Sun; Li-Jing Chen (Natural Product Research, 2019)

Associations between the red blood cell distribution width and primary angle-closure glaucoma: a potential for disease prediction - Qiang Chen; Bin Zhao; Meng-ya Wang; Xue-yu Chen; Dong Li; Xin-quan Jiang; Jing-hui Tian; Yong-jun Liu (EPMA Journal, 2019)

Soil microbial community assemblage and its seasonal variability in alpine treeline ecotone on the eastern Qinghai-Tibet Plateau - Li Kui; Hui Sun; Qian Lei; Wei Gao; Lijun Bao; Yuexi Chen; Zhongjun Jia (Soil Ecology Letters, 2019)

The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway - Ying Xu; Dan Chen; Xiu-Xian Lin; Qing Zhao; Jing Guo; Li-jie Chen; Wei Zhang; Jian Xiao; Guang-Hui Lian; Shi-Fang Peng; Dong Guo; Hong Yang; et al. (Archives of Toxicology, 2019)

Pseudofrancisella aestuarii gen. nov., sp. nov., a novel member of the family Francisellaceae isolated from estuarine seawater - Min-Ling Zheng; Jian-Yu Jiao; Lei Dong; Ming-Xian Han; Liang-Hui Li; Min Xiao; Cha Chen; Ping-Hua Qu; Wen-Jun Li (Antonie van Leeuwenhoek, 2019)

Effect of male sterile and fertile cytoplasm on nuclear DNA methylation in hybrid rice - Asif Ali; Yun Li; Hui Chen; Peizhou Xu; Hongyu Zhang; Xiaoqiong Chen; Liao Yongxiang; Shaohong Fu; Tingkai Wu; Muhammad Zafar Iqbal; Muhammad Umer Farooq; Xianjun Wu (Acta Physiologiae Plantarum, 2019)

Substitution of His260 residue alters the thermostability of Pseudoalteromonas carrageenovora arylsulfatase - Yanbing Zhu; Xiaoqian Yin; Han Liu; Hebin Li; Yanhong Chen; Lijun Li; Anfeng Xiao; Hui Ni (Acta Oceanologica Sinica, 2019)

Apple AP2/EREBP transcription factor MdSHINE2 confers drought resistance by regulating wax biosynthesis - Ya-Li Zhang; Chun-Ling Zhang; Gui-Luan Wang; Yong-Xu Wang; Chen-Hui Qi; Chun-Xiang You; Yuan-Yuan Li; Yu-Jin Hao (Planta, 2019)

Genome-wide investigation of the MADS gene family and dehulling genes in tartary buckwheat (Fagopyrum tataricum) - Moyang Liu; Qiankun Fu; Zhaotang Ma; Wenjun Sun; Li Huang; Qi Wu; Zizhong Tang; Tongliang Bu; Chenglei Li; Hui Chen (Planta, 2019)

Declining diurnal temperature range in the North China Plain related to environmental changes - Weitao Xue; Jianping Guo; Yong Zhang; Shunwu Zhou; Yuan Wang; Yucong Miao; Lin Liu; Hui Xu; Jian Li; Dandan Chen; Huan Liu (Climate Dynamics, 2019)

Analysis of genetic variation of porcine circovirus type 2 within pig populations in central China - Peng-Li Xu; Yu Zhao; Hui-Hua Zheng; Run-Bo Tian; Hao-Ying Han; Hong-Ying Chen; Lan-Lan Zheng (Archives of Virology, 2019)

Spatial and temporal evolution of landfast ice near Zhongshan Station, East Antarctica, over an annual cycle in 2011/2012 - Jiechen Zhao; Qinghua Yang; Bin Cheng; Matti Leppäranta; Fengming Hui; Surui Xie; Meng Chen; Yining Yu; Zhongxiang Tian; Ming Li; Lin Zhang (Acta Oceanologica Sinica, 2019)

Magma–magma interaction in the mantle recorded by megacrysts from Cenozoic basalts in eastern China - Xun Yu; Gang Zeng; Li-Hui Chen; Sen-Lin Hu; Zhi-Qiang Yu (International Geology Review, 2019)

Treatment with MQA, a Derivative of Caffeoylquinic Acid, Provides Neuroprotective Effects against Cerebral Ischemia Through Suppression of the p38 Pathway and Oxidative Stress in Rats - Long Chen; Dan-ni Liu; Yu Wang; Xue-ying Liu; Shuai Han; Ke Zhang; Guo-yu Li; Xing Tian; Hang-yu Wang; Jin-hui Wang (Journal of Molecular Neuroscience, 2019)

Diltiazem used as a tacrolimus-sparing agent for treatment of pediatric patients with refractory nephrotic syndrome: a case report and retrospective analysis - Jie-Yu Sun; Ya-Hui Hu; Hong-Li Guo; Xia Jing; Ze-Jun Xu; Fang Sun; Hui-Lei Guo; Xuan-Sheng Ding; Feng Chen; Jing Xu (European Journal of Clinical Pharmacology, 2019)

The resilience research of the plant and soil optimization design base on the habitat-site design in semiarid green space - Jingmao Wang; Hui Liu; Chundi Chen; Shun Zhang; Feng Guo; Yunyun Li (Environmental Monitoring and Assessment, 2019)

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation - Cheng-cheng Zhang; Chen-guang Li; Yao-feng Wang; Li-hui Xu; Xian-hui He; Qiong-zhen Zeng; Chen-ying Zeng; Feng-yi Mai; Bo Hu; Dong-yun Ouyang (Apoptosis, 2019)

Inhibition of EPAC2 Attenuates Intracerebral Hemorrhage-Induced Secondary Brain Injury via the p38/BIM/Caspase-3 Pathway - Yan Zhuang; Hui Xu; Seidu A. Richard; Jie Cao; Haiying Li; Haitao Shen; Zhengquan Yu; Jian Zhang; Zhong Wang; Xiang Li; Gang Chen (Journal of Molecular Neuroscience, 2019)

Cloning, Expression and Characterization of Two Beta Carbonic Anhydrases from a Newly Isolated CO2 Fixer, Serratia marcescens Wy064 - Fanbing Chen; Wensong Jin; Huifang Gao; Zewang Guo; Hui Lin; Jiahuan Li; Kaihui Hu; Xiong Guan; Vipin C. Kalia; Jung-Kul Lee; Liaoyuan Zhang; Yongyu Li (Indian Journal of Microbiology, 2019)

Novel mutation of type-1 insulin-like growth factor receptor (IGF-1R) gene in a severe short stature pedigree identified by targeted next-generation sequencing - Yu Yang; Hui Huang; Ka Chen; Li Yang; Li-ling Xie; Ting Xiong; Xian Wu (Journal of Genetics, 2019)

Experimental Study and Estimation of Groundwater Fluctuation and Ground Settlement due to Dewatering in a Coastal Shallow Confined Aquifer - Jiong Li; Ming-Guang Li; Lu-Lu Zhang; Hui Chen; Xiao-He Xia; Jin-Jian Chen (Journal of Marine Science and Engineering, 2019)
The coastal micro-confined aquifer (MCA) in Shanghai is characterized by shallow burial depth, high artesian head, and discontinuous distribution. It has a significant influence on underground space development, especially where the MCA is directly connected with deep confined aquifers. In this paper, a series of pumping well tests were conducted in the MCA located in such area to investigate the dewatering-induced groundwater fluctuations and stratum deformation. In addition, a numerical method is proposed for the estimation of hydraulic parameter, and an empirical prediction method is developed for dewatering-induced ground settlement. Test results show that groundwater drawdowns and soil settlement can be observed not only in MCA but also in the aquifers underneath it. This indicates that there is a close hydraulic connection among each aquifer. Moreover, the distributions and development of soil settlement at various depths are parallel to those of groundwater drawdowns in most areas of the test site except the vicinity of pumping wells, where collapse-induced subsidence due to high-speed flow may occur. Furthermore, the largest deformation usually occurs at the top of the pumping aquifer instead of the ground surface, because the top layer is expanded due to the stress arch formed in it. Finally, the proposed methods are validated to be feasible according to the pumping well test results and can be employed to investigate the responses of groundwater fluctuations and stratum deformations due to dewatering in MCA.

Prediction of annual dengue incidence by hydro-climatic extremes for southern Taiwan - Hsiang-Yu Yuan; Tzai-Hung Wen; Yi-Hung Kung; Hsiao-Hui Tsou; Chun-Hong Chen; Li-Wei Chen; Pei-Sheng Lin (International Journal of Biometeorology, 2019)

Two new polyketides from the fungus Penicillium oxalicum MHZ153 - Yi Ren; Ling-Hui Chao; Jing Sun; Xiao-Nan Chen; Hui-Na Yao; Zhi-Xiang Zhu; Dan Dong; Ting Liu; Peng-Fei Tu; Jun Li (Natural Product Research, 2019)

Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides - Qing-Yan Tang; Geng Chen; Wan-Ling Song; Wei Fan; Kun-Hua Wei; Si-Mei He; Guang-Hui Zhang; Jun-Rong Tang; Ying Li; Yuan Lin; Sheng-Chao Yang (Planta, 2019)

Chronic Intracerebroventricular Infusion of Metformin Inhibits Salt-Sensitive Hypertension via Attenuation of Oxidative Stress and Neurohormonal Excitation in Rat Paraventricular Nucleus - Xiao-Jing Yu; Ya-Nan Zhao; Yi-Kang Hou; Hong-Bao Li; Wen-Jie Xia; Hong-Li Gao; Kai-Li Liu; Qing Su; Hui-Yu Yang; Bin Liang; Wen-Sheng Chen; Wei Cui; et al. (Neuroscience Bulletin, 2019)

Hepatoprotective effect of gastrodin against alcohol-induced liver injury in mice - Xin-Xin Li; Zhi-Hui Jiang; Bo Zhou; Chen Chen; Xiao-Ying Zhang (Journal of Physiology and Biochemistry, 2019)

A thiopyran derivative with low murine toxicity with therapeutic potential on lung cancer acting through a NF-κB mediated apoptosis-to-pyroptosis switch - Liping Chen; Bixia Weng; Huimin Li; Haonan Wang; Qian Li; Xiaoyan Wei; Hui Deng; Sicen Wang; Chengxi Jiang; Renyu Lin; Jianzhang Wu (Apoptosis, 2019)

3D-RVSP experimental study above a carbonate outcrop for coal resource exploration - Mingshun Hu; Dongming Pan; Juanjuan Li; Hui Zhang; Shouhua Dong; Shenen Chen; Yongzhong Xu (Acta Geophysica, 2019)

Tropopause trend across China from 1979 to 2016: A revisit with updated radiosonde measurements - Xinyan Chen; Jianping Guo; Jinfang Yin; Yong Zhang; Yucong Miao; Yuxing Yun; Lin Liu; Jian Li; Hui Xu; Kaixi Hu; Panmao Zhai (International Journal of Climatology, 2019)
The long‐term trend in tropopause has profound implications for the expansion of tropical zone and the variation of large‐scale circulation. However, the changes of tropopause in China have not been explicitly investigated as yet. In this study, the trend of lapse rate tropopause (LRT) height over China has been comprehensively revisited for the period of 1979–2016, using the newly released quality‐controlled radiosonde data from China Meteorological Administration. Results show that the LRT height in most parts of China shows a significant upwards trend with a rate of 370 m/decade, most likely due to global warming. The fastest increase occurs in northwest region, followed by the low‐latitude regions (15°–25°N), while the slowest increase occurs in the high‐latitude regions (45°–55°N). Overall, the LRT height varies with latitudes, exhibiting a “south high and north low” pattern. In particular, high LRT height over low latitudes is found to be expanding rapidly polewards in recent years, in contrast to almost constant LRT height over mid and high latitudes. In terms of the seasonality, tropopause height reaches the peak in summer and bottom in winter. The frequency distribution in the vertical direction exhibits a bimodal pattern with the major peak mostly occurring at around 15 km and a secondary peak occurring between 8 and 12 km. This bimodal distribution is similar to the findings revealed in previous studies. Our findings offer important circumstantial observational evidence for the polewards expansion of the Tropics under global warming.

Colletotrichine B, a new sesquiterpenoid from Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla - Xiao-Wei Chen; Zhong-Duo Yang; Xiao-Fei Li; Jian-Hui Sun; Li-Jun Yang; Xin-Guo Zhang (Natural Product Research, 2019)

Daedaleanols A and B, two new sesquiterpenes from cultures of the basidiomycete Daedalea incana - Ying Huang; Shuai-Bing Zhang; He-Ping Chen; Zhen-Zhu Zhao; Zheng-Hui Li; Tao Feng; Ji-Kai Liu (Natural Product Research, 2019)