Correction to: Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport - Jin-Ming Zhang; Ming-Jie Chen; Jiong-Hui He; Ya-Ping Li; Zhi-Cai Li; Zi-Jing Ye; Yong-Hui Bao; Bing-Jun Huang; Wen-Jie Zhang; Ping Kwan; Yu-Ling Mao; Jing-da Qiao (Journal of Molecular Neuroscience, 2023)

Viperin deficiency promotes dendritic cell activation and function via NF-kappaB activation during Mycobacterium tuberculosis infection - Xinying Zhou; Hui Xu; Qianna Li; Qi Wang; Honglin Liu; Yingqi Huang; Yao Liang; Linmiao Lie; Zhenyu Han; Yaoxin Chen; Yulan Huang; Wenle Zhou; et al. (Inflammation Research, 2023)
Objectives and design Dendritic cells (DCs) are one of the key immune cells in bridging innate and adaptive immune response against Mycobacterium tuberculosis (Mtb) infection. Interferons (IFNs) play important roles in regulating DC activation and function. Virus-inhibitory protein, endoplasmic reticulum-associated, interferon-inducible (Viperin) is one of the important IFN-stimulated genes (ISGs), and elicits host defense against infection. Methods We investigated the effects and mechanisms of Viperin on DC activation and function using Viperin deficient bone marrow-derived dendritic cells (BMDCs) during Mtb infection. Results Viperin deficiency enhanced phagocytic activity and increased clearance of Mtb in DCs, produced higher abundance of NO, cytokine including interleukin-12 (IL-12), Tumor necrosis factor-α (TNF- α ), IL-1 β , IL-6 and chemokine including CXCL1, CXCL2 and CXCL10, elevated MHC I, MHC II and co-stimulatory molecules expression, and enhanced CD4 + and CD8 + T cell responses. Mechanistically, Viperin deficiency promoted DC activation and function through NF-κB p65 activation. NF-κB p65 inhibitor prevented cytokine and chemokine production, and co-stimulatory molecules expression promoted by Viperin deficiency. Conclusions These results suggest that Mtb induced Viperin expression could impair the activation of host defense function of DCs and DC-T cell cross talk during Mtb infection. This research may provide a potential target for future HDT in TB therapy.

Exploration of long afterglow luminescent materials composited with graphitized carbon nitride for photocatalytic degradation of basic fuchsin - Shan-Shan Li; Min Liu; Li Wen; Zhou Xu; Yun-Hui Cheng; Mao-Long Chen (Environmental Science and Pollution Research, 2023)

Key technology for the construction and inspection of long-distance underwater tunnel for 1000 kV gas-insulated transmission line - Xiao-Ping Zhang; Shao-Hui Tang; Quan-Sheng Liu; Hao-Jie Wang; Xin-Fang Li; Peng Chen; Hao Liu (Bulletin of Engineering Geology and the Environment, 2023)

Solar ring mission: Building a panorama of the Sun and inner-heliosphere - Yuming Wang; Xianyong Bai; Changyong Chen; Linjie Chen; Xin Cheng; Lei Deng; Linhua Deng; Yuanyong Deng; Li Feng; Tingyu Gou; Jingnan Guo; Yang Guo; et al. (Advances in Space Research, 2023)

Effects of land clearing for agriculture on soil organic carbon stocks in drylands: A meta‐analysis - Yuangang Wang; Geping Luo; Chaofan Li; Hui Ye; Haiyang Shi; Binbin Fan; Wenqiang Zhang; Chen Zhang; Mingjuan Xie; Yu Zhang (Global Change Biology, 2023)
Agricultural activities have been expanding globally with the pressure to provide food security to the earth's growing population. These agricultural activities have profoundly impacted soil organic carbon (SOC) stocks in global drylands. However, the effects of clearing natural ecosystems for cropland (CNEC) on SOC are uncertain. To improve our understanding of carbon emissions and sequestration under different land uses, it is necessary to characterize the response patterns of SOC stocks to different types of CNEC. We conducted a meta‐analysis with mixed‐effect model based on 873 paired observations of SOC in croplands and adjacent natural ecosystems from 159 individual studies in global drylands. Our results indicate that CNEC significantly ( p p −1 ). The results derived from our meta‐analysis could be used for refining the estimation of dryland carbon dynamics and developing SOC sequestration strategies to achieve the removal of CO 2 from the atmosphere.

Warming reduced flowering synchrony and extended community flowering season in an alpine meadow on the Tibetan Plateau - Yaya Chen; Scott L. Collins; Yunpeng Zhao; Tianwu Zhang; Xiangrong Yang; Hang An; Guorui Hu; Chunming Xin; Juan Zhou; Xiongjie Sheng; Mingrui He; Panhong Zhang; et al. (Ecology, 2023)
The timing of phenological events is highly sensitive to climate change, and may influence ecosystem structure and function. Although changes in flowering phenology among species under climate change have been reported widely, how species‐specific shifts will affect phenological synchrony and community‐level phenology patterns remains unclear. We conducted a manipulative experiment of warming and precipitation addition and reduction to explore how climate change affected flowering phenology at the species and community levels in an alpine meadow on the eastern Tibetan Plateau. We found that warming advanced the first and last flowering times differently and with no consistent shifts in flowering duration among species, resulting in the entire flowering period of species emerging earlier in the growing season. Early‐flowering species were more sensitive to warming than mid‐ and late‐flowering species, thereby reducing flowering synchrony among species and extending the community‐level flowering season. However, precipitation and its interactions with warming had no significant effects on flowering phenology. Our results suggest that temperature regulates flowering phenology from the species to community levels in this alpine meadow community, yet how species shifted their flowering timing and duration in response to warming varied. This species‐level divergence may reshape flowering phenology in this alpine plant community. Decreasing flowering synchrony among species and the extension of community‐level flowering seasons under warming may alter future trophic interactions, with cascading consequences to community and ecosystem function.

Coupling phytotoxicity and human health risk assessment to refine the soil quality standard for As in farmlands - Kai-Wei Juang; Li-Jia Chu; Chien-Hui Syu; Bo-Ching Chen (Environmental Science and Pollution Research, 2022)

The signal-to-cutoff ratios to predict HCV infection among people who inject drugs - Bing Chen; Ling-yu Gao; Zhong-hui Ma; Hao Chang; Li-jian Pei; Qiang Zhou; Wen-ge Xing (VirusDisease, 2022)

Environmental impact of typical zinc smelting that implements solid waste collaborative utilization in China - Wei-Ning Liu; Yao Shi; Chen-Mu Zhang; Lang-Ming Liu; Hui-Quan Li; Bin Lu; Yuan-Bo Xie; Cai-Bei Zhuang; Tian-You Sun; Wei-Ping Liu; Xue Guan; Ying-Yan Hu (The International Journal of Life Cycle Assessment, 2022)

The landscape of aging - Yusheng Cai; Wei Song; Jiaming Li; Ying Jing; Chuqian Liang; Liyuan Zhang; Xia Zhang; Wenhui Zhang; Beibei Liu; Yongpan An; Jingyi Li; Baixue Tang; et al. (Science China Life Sciences, 2022)

Shanghai Autism Early Development: An Integrative Chinese ASD Cohort - Yuan Dai; Yuqi Liu; Lingli Zhang; Tai Ren; Hui Wang; Juehua Yu; Xin Liu; Zilin Chen; Lin Deng; Minyi Tao; Hangyu Tan; Chu-Chung Huang; et al. (Neuroscience Bulletin, 2022)

Transplantation of Nasal Olfactory Mucosa Mesenchymal Stem Cells Benefits Alzheimer’s Disease - Chun-Gu Hong; Meng-Lu Chen; Ran Duan; Xin Wang; Zhi-Lin Pang; Li-Te Ge; Ming Lu; Hui Xie; Zheng-Zhao Liu (Molecular Neurobiology, 2022)

An association study on the risk, glucocorticoids effectiveness, and prognosis of systemic lupus erythematosus: insight from mitochondrial DNA copy number - Zhen Li; Qi-Qun Zong; Chun-Xia Zhai; Guang-Hui Yu; Wan-Qin Hu; Yu-Hua Wang; Lin-Lin Wang; Zi-Ye Yan; Ting-Yu Zhang; Ying Teng; Shuang Liu; Jing Cai; et al. (Immunologic Research, 2022)

Study on the Relationship Between Diet, Physical Health and Gut Microflora of Chinese College Students - Xiafen Hu; Jiaqi Guo; Jiadun Wang; Wanxin Liu; Xiaochen Xiang; Siyang Chen; Xinquan Li; Jinhan Tang; Wei Zhang; Hui Chen; Rong Shu; Qingming Wu; et al. (Current Microbiology, 2022)

Olivine and melt inclusion chemical constraints on the nature and origin of the common mantle component beneath eastern Asia - Jian-Qiang Liu; Li-Hui Chen; Xiao-Jun Wang; Hui-Li Zhang; Gang Zeng; Saskia Erdmann; Le Zhang; Zhong-Yuan Ren (Contributions to Mineralogy and Petrology, 2022)

A water-soluble polysaccharide from Eucommia folium: the structural characterization and anti-tumor activity in vivo - Zhi-Qian Yan; Su-Yun Ding; Pei Chen; Hui-Ping Liu; Meng-Li Chang; Shu-Yuan Shi (Glycoconjugate Journal, 2022)

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression - Qin Jin; Xiaoyu Yang; Shixue Gou; Xiaoyi Liu; Zhenpeng Zhuang; Yanhui Liang; Hui Shi; Jiayuan Huang; Han Wu; Yu Zhao; Zhen Ouyang; Quanjun Zhang; et al. (Science China Life Sciences, 2022)

The association between hearing threshold and urinary personal care and consumer product metabolites in middle-aged and elderly people from the USA - Yan-Peng Fu; Wen-Yu Chen; Li-Qing Guo; Ya-Qiong Zhu; Jia-Sheng Yuan; Yue-Hui Liu (Environmental Science and Pollution Research, 2022)

Dietary exposure and risk assessment of chlorinated paraffins in roots and rhizomes of traditional Chinese medicine herbs - Huijuan Li; Hui Li; Shishan Zhang; Huizhi Li; Yanfang Zhao; Xiangfeng Chen; Zongwei Cai (Environmental Science and Pollution Research, 2022)

A histological study of vascular wall resident stem cells in venous malformations - Hou-Fu Xia; Wen-Qiang Lai; Gao-Hong Chen; Ye Li; Qi-Hui Xie; Yu-Lin Jia; Gang Chen; Yi-Fang Zhao (Cell and Tissue Research, 2022)

Complete genome sequence of Aconitum amalgavirus 1, a distinct member of the genus Amalgavirus - Jie Yang; Ping-Xiu Lan; Jin-Ming Li; Xiao-Jiao Chen; Guan-Lin Tan; Tai-Yun Wei; Ru-Hui Li; Fan Li (Archives of Virology, 2022)

Contrasting effects of altered precipitation regimes on soil nitrogen cycling at the global scale - Qiqian Wu; Kai Yue; Yuandan Ma; Petr Heděnec; Yanjiang Cai; Jian Chen; Hui Zhang; Junjiong Shao; Scott X. Chang; Yan Li (Global Change Biology, 2022)
Changes in precipitation regimes can strongly affect soil nitrogen (N) cycling in terrestrial ecosystems. However, whether altered precipitation regimes may differentially affect soil N cycling between arid and humid biomes at the global scale is unclear. We conducted a meta‐analysis using 1036 pairwise observations collected from 194 publications to assess the effects of increased and decreased precipitation on the input (N return from plants), storage (various forms of N in soil), and output (gaseous N emissions) of soil N in arid versus humid biomes at the global scale. We found that (1) increased precipitation significantly increased N input (+12.1%) and output (+34.9%) but decreased N storage (−13.7%), while decreased precipitation significantly decreased N input (−10.7%) and output (−34.8%) but increased N storage (+11.1%); (2) the sensitivity of soil N cycling to increased precipitation was higher in arid regions than in humid regions, while that to decreased precipitation was lower in arid regions than in humid regions; (3) the effect of altered precipitation regimes on soil N cycling was independent of precipitation type (i.e., rainfall vs. snowfall); and (4) the mean annual precipitation regulated soil N cycling in precipitation alteration experiments at the global scale. Overall, our results clearly show that the response of soil N cycling to increased versus decreased precipitation differs between arid and humid regions, indicating the uneven effect of climate change on soil N cycling between these two contrasting climate regions. This implies that ecosystem models need to consider the differential responses of N cycling to altered precipitation regimes in different climatic conditions under future global change scenarios.

Photosynthetic regulation in response to strontium stress in moss Racomitrium japonicum L - Hui Ren; Renhua Huang; Ying Li; Wanting Li; Liuliu Zheng; Yanbao Lei; Ke Chen (Environmental Science and Pollution Research, 2022)

Two new triterpenoid glycosides from leaves of Cyclocarya paliurus - Huihui Sun; Hui Zhu; Jianping Wu; Yuyan Wang; Guihua Li; Yiqian Liu; Xiwen Chang; Saiyu Ou; Wenwen Zha; Huiyun Chen; Rui Gui; Xiaoai He; et al. (Natural Product Research, 2022)

Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells - Yue Wang; Hui-Li Wang; Zhi-Ping Lin; Ji-Feng Zhong; Kun-Lin Chen; Xing Duan (Molecular Biology Reports, 2022)

First report of Bacillus velezensis JK-F2 for the biological control of crown gall in kiwifruit - Ting Ting Chen; Fei Ran; Jin Qiao Shi; Fei Xu Mo; Xian Hui Yin; Zhi Bo Zhao; Zhu Zhu Zhang; Wen Zhi Li; Li Nan He; You Hua Long (Journal of Plant Diseases and Protection, 2022)

IGFBP2 function as a novel biomarker for active lupus nephritis - Hui Li; Jun Liang; Yingying Gao; Min Liu; Nan Xia; Wei Kong; Lisha Zheng; Yikun Zhang; Zutong Li; Hongwei Chen; Shanshan Liu; Lingyun Sun (Journal of Molecular Medicine, 2022)
In search for new targets for the diagnosis and treatment of lupus nephritis (LN), we employed TMT-liquid chromatography-triple quadrupole mass spectrometry (TMT-LC–MS/MS) combined with RNA-seq and identified a panel of proteins that was dysregulated both at protein level and mRNA level in active LN patients compared with healthy controls. We chose to study the role of IGFBP2 since it is a relatively understudied protein in the context of LN. We further validated that IGFBP2 significantly increased and correlated with SLE activity index in active LN patients. The receiver operator characteristic (ROC) curve suggested that plasma IGFBP2 had a high diagnostic efficiency for distinguishing between inactive and active LN patients (AUC = 0.992; 95% CI = 0.974–1.000; P < 0.001). We demonstrated neutralizing IGFBP2-downregulated CD4 + T cell activation, upregulated the ratio of Treg, downregulated AKT/mTOR/4E-BP1 pathway, and significantly improved nephritis in MRL/lpr mice. In all, our work demonstrated IGFBP2 as a biomarker specific for active LN and blocking IGFBP2 could be a new target for treating LN. Key messages Plasma IGFBP2 is a promising diagnostic marker for distinguishing stable LN from active LN, and it is also a predictor for the poor prognosis of LN. Blockade of IGFBP2 can significantly improve the pathological damage of LN. IGFBP2 may regulate activation of CD4 + T and Treg ratio. Neutralizing IGFBP2 downregulates AKT/mTOR/4E-BP1 pathway.

Identification of a 5-gene-risk score model for predicting luminal A-invasive lobular breast cancer survival - Yi-Huan Chen; Tao-Feng Zhang; Yi-Yuan Liu; Jie-Hua Zheng; Wei-Xun Lin; Yao-Kun Chen; Jie-Hui Cai; Juan Zou; Zhi-Yang Li (Genetica, 2022)

Correction to: Protective effects of fowl‑origin cadmium‑tolerant lactobacillus against sub‑chronic cadmium‑induced toxicity in chickens - Da‑Wei Chen; Hui‑Jia Li; YinYin Liu; Li‑Na Ma; Jun‑Hua Pu; JunXian Lu; Xiu‑Jun Tang; Yu‑shi Gao (Environmental Science and Pollution Research, 2022)

Protective effects of fowl-origin cadmium-tolerant lactobacillus against sub-chronic cadmium-induced toxicity in chickens - Da-Wei Chen; Hui-Jia Li; YinYin Liu; Li-Na Ma; Jun-Hua Pu; JunXian Lu; Xiu-Jun Tang; Yu-shi Gao (Environmental Science and Pollution Research, 2022)

Maternal exposure to cooking oil fumes during pregnancy and autistic‐like behaviors in Chinese preschoolers - Jian-Hui Yang; Esben Strodl; Chuan-An Wu; Xiang-Yu Hou; Xiao-Na Yin; Guo-Min Wen; Deng-Li Sun; Dan-Xia Xian; Jing-Yi Chen; Ying-Jie Chen; Jing Chen; Wei-Qing Chen (Environmental Science and Pollution Research, 2022)

Urinary cadmium and peripheral blood telomere length predict the risk of renal function impairment: a study of 547 community residents of Shanxi, China - Jia-Chen Zhang; Shuang-Jing Li; Jian-Yong Guo; Guo-Yan Zhang; Hui Kang; Xiu-Jing Shi; Han Zhou; Yu-Fen Liang; Wei-Tong Shen; Li-Jian Lei (Environmental Science and Pollution Research, 2022)

Starch, cellulose and plant extracts as green inhibitors of metal corrosion: a review - Li Huang; Wei-Qiang Chen; Shan-Shan Wang; Qing Zhao; Hui-Jing Li; Yan-Chao Wu (Environmental Chemistry Letters, 2022)

Green building performance assessment in China using a cloud model - Xiao-Juan Li; Chen Wang; Wei-bin Chen; Shilpi Bora; Jeffrey Boon Hui Yap; Bimenyimana Samuel (Environment, Development and Sustainability, 2022)

The effect of Fe–Ti oxide separation on iron isotopic fractionation during basalt differentiation - Jian Zhao; Xiao-Jun Wang; Li-Hui Chen; Takeshi Hanyu; Jin-Hua Shi; Xiao-Wen Liu; Hiroshi Kawabata; Lie-Wen Xie (Contributions to Mineralogy and Petrology, 2022)

Gray matter alteration in medication overuse headache: a coordinates-based activation likelihood estimation meta-analysis - Wenjia Chen; Hui Li; Xiaoyan Hou; Xize Jia (Brain Imaging and Behavior, 2022)
Medication overuse headache (MOH) is a prevalent secondary headache, bringing heavy economic burden and neuropsychological damage. Neuroimaging studies on the disease reported divergent results. To merge the reported neuroimaging alterations in MOH patients and explore a pathophysiological mechanism of this disorder. A meta-analytic activation likelihood estimation (ALE) analysis method was used. We systematically searched English and Chinese databases for both morphological and functional neuroimaging studies published before Nov 18, 2021. Reported altered brain regions and the stereotactic coordinates of their peaks were extracted and pooled by GingerALE using Gaussian probability distribution into brain maps, illustrating converged regions of alteration among studies. We identified 927 articles, of which five studies on gray matter changes, using voxel-based morphometry (VBM) were eventually included for ALE analysis, with 344 subjects and 54 coordinates put into GingerALE. No functional magnetic resonance imaging (fMRI) or positron emission topography (PET) studies were included for pooling. Compared with healthy controls (HCs), MOH featured increased gray matter density in midbrain, striatum, cingulate, inferior parietal cortex and cerebellum ( P < 0.001 uncorrected), whereas decreased gray matter density in orbitofrontal cortex ( P < 0.05, family-wise error), frontal, insular and parietal cortices ( P < 0.001 uncorrected). Withdrawal of analgesics led to decreased gray matter density in superior temporal gyrus, cuneus, midbrain and cerebellum ( P < 0.001 uncorrected). This meta-analysis confirmed that medication overuse headache is associated with morphologic alteration in the reward system, the prefrontal cortex and a reversible modification in the pain network. Further functional imaging paradigms and longitudinal studies are required for a more definite conclusion and a causal mechanism.

Duck sewage source coliphage P762 can lyse STEC and APEC - Xuewei Kong; Hui Wang; Genglin Guo; Pei Li; Panpan Tong; Maojun Liu; Xun Ma; Chen Dong; Yubao Li; Haiyan Zhang; Wei Zhang (Virus Genes, 2022)

Permian-Triassic magmatic and thermal events in the Dunhuang orogenic belt: implications for subduction records of the Paleo-Asian Ocean - Qian W.L. Zhang; Yi-Chao Chen; Meng-Yan Shi; Zhen M.G. Li; Jia-Hui Liu; Chun-Ming Wu (International Geology Review, 2022)

Determination of extractable and non-extractable florfenicol residues as florfenicol amine in eggs by UPLC-MS/MS - Xia Li; Yu Zhang; Qifan Sun; Min Ding; Zengmei Li; Hui Yue; Ligang Deng; Lu Chen (Food Additives & Contaminants: Part A, 2022)

In sharing and explaining the history of socio-ecological practice, we must act as intergenerational mediators between the past and present historymakers - Yuncai Wang; Hui Wang; Wentao Yan; Wei Gao; Chundi Chen; Ying Chen; Wei-Ning Xiang; Yiman Li (Socio-Ecological Practice Research, 2022)

Late Mesozoic rifting and its deep dynamic mechanisms in the central Sulu orogenic belt: Records from Lingshan Island - Tengfei Zhou; Yaoqi Zhou; Nina Søager; Paul Martin Holm; Zhenkai Zhang; Jun Wang; Zhao Liang; Hongyu Mu; Yanjun Cheng; Feifei Liu; Miao Wang; Yue Zhang; et al. (Science China Earth Sciences, 2022)

CircRNA.0007127 triggers apoptosis through the miR-513a-5p/CASP8 axis in K-562 cells - Xiajing Li; Yiyu Zhang; Ning Wang; Zhaohu Yuan; Xiaojie Chen; Qicong Chen; Hui Deng; Xinxin Tong; Honglin Chen; Yuyou Duan; Yaming Wei (Journal of Zhejiang University-SCIENCE B, 2022)

Prediction of groundwater level using the hybrid model combining wavelet transform and machine learning algorithms - Aihua Wei; Yuanyao Chen; Duo Li; Xianfu Zhang; Tao Wu; Hui Li (Earth Science Informatics, 2022)

Correction to: Future precipitation changes in three key sub-regions of East Asia: the roles of thermodynamics and dynamics - Jiao Li; Yang Zhao; Deliang Chen; Yanzhen Kang; Hui Wang (Climate Dynamics, 2022)

Future precipitation changes in three key sub-regions of East Asia: the roles of thermodynamics and dynamics - Jiao Li; Yang Zhao; Deliang Chen; Yanzhen Kang; Hui Wang (Climate Dynamics, 2022)
Previous studies have projected an increase in future summer precipitation across East Asia (EA). This study investigates the relative contributions of thermodynamic and dynamic components to future precipitation changes in three key sub-regions of EA where the maximum centers of the historical precipitation are located (the tropical region, East China, and the Japan and Korea sector), and analyzes the causes of the changes in thermodynamic and dynamic components. Outputs from 30 climate models of the Coupled Model Intercomparison Project Phase 6 (CMIP6) are used. From these, the five best-performing models for historical summer precipitation climatology for EA are selected. The future summer precipitations in the three sub-regions over the near- to mid-term (2020–2069) and the long-term (2070–2095) are then examined using the multi-model ensemble mean of the five models selected (MMM05). The projections were driven by four combined scenarios of the Shared Socioeconomic Pathways (SSPs) and forcing levels of the Representative Concentration Pathways (SSP1-2.6, SSP2-4.5, SSP3-7.0, and SSP5-8.5). The results show that long-term precipitations under SSP5-8.5 are greater than those under the other scenarios across all sub-regions. After the 2070s under SSP5-8.5, a marked precipitation intensification is identified in all three sub-regions, but with different rates of increase. The projected precipitation increase is primarily attributed to the thermodynamic component, while the dynamic component related to circulation changes is relatively weak. Further analysis indicates that the pattern of the thermodynamic component in the three sub-regions is dominated by the climatological upward motion, mediated by an increase in moisture.

MicroRNA-223 downregulation promotes HBx-induced podocyte pyroptosis by targeting the NLRP3 inflammasome - Yani Yu; Hui Dong; Yue Zhang; Jingyi Sun; Baoshuang Li; Yueqi Chen; Moxuan Feng; Xiaoqian Yang; Shengbo Gao; Wei Jiang (Archives of Virology, 2022)

Distribution characteristics of delta reservoirs reshaped by bottom currents: A case study from the second member of the Yinggehai Formation in the DF1-1 gas field, Yinggehai Basin, South China Sea - Shuo Chen; Renhai Pu; Huiqiong Li; Hongjun Qu; Tianyu Ji; Siyu Su; Yunwen Guan; Hui Zhang (Acta Oceanologica Sinica, 2022)

Two new pyridine derivatives and two new furan derivatives from Irpex lacteus - Qiong Chen; Meng Wang; Xue-Wen Yi; Zheng-Hui Li; Tao Feng; Ji-Kai Liu (Natural Product Research, 2022)

Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport - Jin-Ming Zhang; Ming-Jie Chen; Jiong-Hui He; Ya-Ping Li; Zhi-Cai Li; Zi-Jing Ye; Yong-Hui Bao; Bing-Jun Huang; Wen-Jie Zhang; Ping Kwan; Yu-Ling Mao; Jing-da Qiao (Journal of Molecular Neuroscience, 2022)

Ginsenoside Rb3 attenuates skin flap ischemia-reperfusion damage by inhibiting STING-IRF3 signaling - Yuanbin Li; Haifen Liu; Zhaohui Zeng; Hui Lin; Xin Chen; Xianglian Yuan; Jizhe Qiu; Fengchun Fu; Zhuang Chen; Jianjun Kuang (Journal of Molecular Histology, 2022)

Identification of novel genes in Behcet’s disease using integrated bioinformatic analysis - Si Chen; Haolong Li; Haoting Zhan; Xiaoli Zeng; Hui Yuan; Yongzhe Li (Immunologic Research, 2022)
Behcet’s disease (BD) is a chronic vascular inflammatory disease. However, the etiology and molecular mechanisms underlying BD development have not been thoroughly understood. Gene expression data for BD were obtained from the Gene Expression Omnibus database. We used robust rank aggregation (RRA) to identify differentially expressed genes (DEGs) between patients with BD and healthy controls. Gene ontology functional enrichment was used to investigate the potential functions of the DEGs. Protein–protein interaction (PPI) network analysis was performed to identify the hub genes. Receiver operating characteristic analyses were performed to investigate the value of hub genes in the diagnosis of BD. GSE17114 and GSE61399 datasets were included, comprising 32 patients with BD and 26 controls. The RRA integrated analysis identified 44 significant DEGs among the GSE17114 and GSE61399 CD4 + T lymphocytes. Functional enrichment analysis revealed that protein tyrosine/threonine phosphatase activity and immunoglobulin binding were enriched in BD. PPI analysis identified FCGR3B as a hub gene in the CD4 + T lymphocytes of BD patients. Our bioinformatic analysis identified new genetic features, which will enable further understanding of the pathogenesis of BD.

Differential responses of polysaccharides and antioxidant enzymes in alleviating cadmium toxicity of tuber traditional Chinese medicinal materials - Li Yang; Yuchen Kang; Haibo Dai; Xiaoqin Wang; Mengdi Xie; Jiaxin Liu; Cheng Gao; Hui Sun; Tianqi Ao; Wenqing Chen (Environmental Science and Pollution Research, 2022)

Relationship between summer extreme precipitation anomaly in Central Asia and surface sensible heat variation on the Central-Eastern Tibetan Plateau - Hui Wang; Jie Zhang; Lian Chen; Dongliang Li (Climate Dynamics, 2022)
In the context of global warming, the frequency and intensity of extreme weather and climate events have increased, especially in Central Asia (CA). In this study, we investigate the characteristics of summer extreme precipitation (SEP) in CA and its relationship with the surface sensible heat (SSH) variation over the central–eastern Tibetan Plateau (CETP). The results suggest that the distribution of SEP in CA is extremely uneven, and the SEP thresholds range from 2 to 32 mm/day, and 80% of them are concentrated in 4–10 mm/day. Both the total amount of SEP and the number of SEP days show significant increasing trends, with the climatic tendencies of 4.4 mm/decade and 0.4 day/decade, respectively. The SSH anomalies over the CETP can affect the SEP and summer drought in CA by regulating the strength of South Asia High (SAH) and the subtropical jet over CA. The strong SSH anomalies over the CETP in late spring (April–May) can be transmitted from the lower to the upper layers through the continuous heating to the atmosphere and lead to the anomalously strong subtropical high over northern Africa and the Arabian Peninsula, the anomalously weak subtropical westerly jet over CA and the anomalously strong SAH in summer. At the same time, the Ural ridge strengthens, the CA trough weakens, and the northern CA is controlled by an anomaly of warm high-pressure ridge. Therefore, the anomaly of water vapor convergence in northern CA weakens. The SEP there will be abnormally less, and the summer drought intensifies. When the SSH over CETP is anomalously weak in late spring, the key circulations are just the opposite. Furthermore, the anomalous water vapor from the Arctic, North Atlantic and western Pacific converges in northern CA and northern Xinjiang, China, which is conducive to the generation of widespread extreme precipitation and the alleviation of summer drought in these regions.

Association between resting-state functional connectivity of amygdala subregions and peripheral pro-inflammation cytokines levels in bipolar disorder - Jiaying Gong; Guanmao Chen; Feng Chen; Shuming Zhong; Pan Chen; Hui Zhong; Shunkai Lai; Guixian Tang; Jurong Wang; Zhenye Luo; Zhangzhang Qi; Yanbin Jia; et al. (Brain Imaging and Behavior, 2022)

Cloning, identification, and functional analysis of chalcone isomerase gene and its promoter from Tartary buckwheat - Guohui Nan; Huala Wu; Qiong Wu; Lisong Liu; Qiancheng Liao; Chenglei Li; Hui Chen; Qi Wu (Acta Physiologiae Plantarum, 2022)

Research on an Extensible Monitoring System of a Seafloor Observatory Network in Laizhou Bay - Jie Chen; Hailin Liu; Bin Lv; Chao Liu; Xiaonan Zhang; Hui Li; Lin Cao; Junhe Wan (Journal of Marine Science and Engineering, 2022)
An extensible remote monitoring system for a seafloor observatory network in Laizhou Bay was established to realize long-term, continuous and on-line monitoring for a marine ranching environment. This paper deals with data communication, device management and data quality control. A control model is introduced that is structured into four layers, enabling bidirectional information flow. Based on the control model, the standardized communication protocol and device object model-oriented dynamic management method are designed as plug-and-play, for data processing and control of a large number of devices. An improved data quality control method is proposed to reduce the data error rate. The monitoring system was developed based on socket network programming, MySQL database technologies and modular ideas. The seafloor observatory network was successfully deployed in Laizhou Bay marine ranching. The experimental results demonstrate that the monitoring system obtains better performance. The proposed algorithms can also be used in many other similar systems with adaptive requirements.

Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum - Li Cheng; Xi Zheng; Qin Li; Meng-Sha Wei; Chun-Mei Chen; Hu-Cheng Zhu; Chang-Li Zeng; Xin-Cai Hao; Yong-Hui Zhang (Natural Product Research, 2022)

Editorial: Biological and Ecological Studies on Marine Ichthyoplankton - Hui Zhang; Yuan Li; Chen Jiang (Frontiers in Marine Science, 2022)

Application of an improved hollow fiber liquid phase microextraction technique coupled to LC-MS/MS to studying migration of fluorescent whitening agents from plastic food contact materials - Wen-Li Zhou; Li Ding; Yun-Hui Cheng; Zhou Xu; Mao-Long Chen; Xian-Shu Fu (Food Additives & Contaminants: Part A, 2022)

Geographic information system and system dynamics combination technique for municipal solid waste treatment station site selection - Chen Wang; Fengqiu Zou; Jeffrey Boon Hui Yap; Rui Tang; Heng Li (Environmental Monitoring and Assessment, 2022)

Grain size-dependent geochemical evidence reveals provenance and implications of aeolian sands, Dinggye region, southern Tibet - You-gui Chen; Mei-hui Pan; Ze-wen Hao; Yu-han Qi; Chen-lu Li (Journal of Mountain Science, 2022)

Streptococcus vulneris sp. nov., isolated from wound of patient with diabetic foot ulcer (DFU) - Jen-hao Chung; Li-Ting Wang; Yi-Sheng Chen; Yun-Shien Lee; Shih-Ting Lin; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Jui-hsiang Li (Archives of Microbiology, 2022)

The tetrameric assembly of 2‐aminomuconic 6‐semialdehyde dehydrogenase is a functional requirement of cofactor NAD + binding - Qiuli Shi; Yanjuan Chen; Xinxin Li; Hui Dong; Cheng Chen; Zhihui Zhong; Cheng Yang; Guangfeng Liu; Dan Su (Environmental Microbiology, 2022)
Summary The bacterium Pseudomonas sp. AP‐3 is able to use the environmental pollutant 2‐aminophenol as its sole source of carbon, nitrogen, and energy. Eight genes (amnA, B, C, D, E, F, G, and H) encoding 2‐aminophenol metabolizing enzymes are clustered into a single operon. 2‐Aminomuconic 6‐semialdehyde dehydrogenase (AmnC), a member of the aldehyde dehydrogenase (ALDH) superfamily, is responsible for oxidizing 2‐aminomuconic 6‐semialdehyde to 2‐aminomuconate. In contrast to many other members of the ALDH superfamily, the structural basis of the catalytic activity of AmnC remains elusive. Here, we present the crystal structure of AmnC, which displays a homotetrameric quaternary assembly that is directly involved in its enzymatic activity. The tetrameric state of AmnC in solution was also presented using small‐angle X‐ray scattering. The tetramerization of AmnC is mediated by the assembly of a protruding hydrophobic beta‐strand motif and residues V121 and S123 located in the NAD + ‐binding domain of each subunit. Dimeric mutants of AmnC dramatically lose NAD + binding affinity and failed to oxidize the substrate analogue 2‐hydroxymuconate‐6‐semialdehyde to α‐hydroxymuconic acid, indicating that tetrameric assembly of AmnC is functional requirement.

Otolith Marking With Strontium for Stock Assessment in Coilia nasus - Ming-Zhi Liu; Ri-jin Jiang; Hui Zhang; Fan Yang; Xia-Fang Li; Guang-Peng Feng; Rui Yin; Feng Chen (Frontiers in Marine Science, 2022)
Mass stock enhancement and release are excellent ways to recover Coilia nasus resources. However, it is challenging to evaluate stock enhancement effectively, and it is important to establish a method suitable for estimating C. nasus populations. We explored the effectiveness of marking otoliths in these fish with strontium by immersing C. nasus in hexahydrate strontium chloride solutions. We used laser ablation inductively coupled plasma mass spectrometry to measure the strontium content of otoliths and fish bodies. The larvae (40 d post hatch) were reared in five different concentrations of strontium (0, 12, 24, 48, and 60 mg/L) for 7 d, followed by treatment in non-additive water for 3 wk. The results showed that the cumulative mortality rate was not significantly different between treatment and control groups ( P >0.05), except in the group treated with 24 mg/L strontium. The swimming and feeding behaviors did not change significantly, indicating that strontium did not negatively affect survival in this species. The strontium/calcium ratios of otoliths in the control group were stable (1.78–2.32 mmol/mol), whereas those of the experimental (marked) groups ranged widely (4.47–61.02 mmol/mol). The strontium/calcium ratios increased with increasing strontium concentration, but gradually returned to baseline values, resulting in a 100% success rate of marking with strontium. Following immersion in 12 mg/L strontium, strontium levels in the body returned to normal after 24 d. In summary, a treatment of 12 mg/L strontium for 4 d was identified as viable for marking. We confirmed the feasibility of strontium marking for the mass marking and release of C. nasus . This marking method does not affect the physiology of the fish and may provide a new approach for reasonable and scientific stock assessment of C. nasus post hatch.

Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities - Lu Luo; Jun Yang; Cheng Wang; Jie Wu; Yafang Li; Xu Zhang; Hui Li; Hui Zhang; Yumei Zhou; Aiping Lu; Shilin Chen (Science China Life Sciences, 2022)

Genome-Wide Identification and Expression Analyses of CONSTANS-Like Family Genes in Cucumber (Cucumis sativus L.) - Zhen Tian; Xiaodong Qin; Hui Wang; Ji Li; Jinfeng Chen (Journal of Plant Growth Regulation, 2022)
The CONSTANS - like ( COL ) gene family is one of the plant-specific transcription factor families that play important roles in plant growth and development. However, the knowledge of COLs related in cucumber is limited, and their biological functions, especially in the photoperiod-dependent flowering process, are still unclear. In this study, twelve CsaCOL genes were identified in the cucumber genome. Phylogenetic and conserved motif analyses provided insights into the evolutionary relationship between the CsaCOLs . Further, the comparative genome analysis revealed that COL genes are conserved in different plant species, especially collinearity gene pairs related to CsaCOL5 . Ten kinds of cis-acting elements were vividly detected in CsaCOLs promoter regions, including five light-responsive elements, which echo the diurnal rhythm expression patterns of seven CsaCOL genes under SD and LD photoperiod regimes. Combined with the expression data of developmental stage, three CsaCOL genes are involved in the flowering network and play pivotal roles for the floral induction process. Our results provide useful information for further elucidating the structural characteristics, expression patterns, and biological functions of COL family genes in many plants

Arbuscular mycorrhizal fungal colonization improves growth, photosynthesis, and ROS regulation of split-root poplar under drought stress - Haoqiang Zhang; Li Li; Wei Ren; Wenrui Zhang; Ming Tang; Hui Chen (Acta Physiologiae Plantarum, 2022)

Pulmonary Infection Caused by Strongyloides stercoralis - Lingqing Xu; Qianjun He; Linjuan Chen; Jiaxi Lv; Yinxian Tang; Yuzhen Li; Zhongwen Zhang; Weihong Wen; Guoquan Zhong; Hui Liu; Bishi Fu (Acta Parasitologica, 2022)

Mycorrhizal fungi alleviate acidification‐induced phosphorus limitation: Evidence from a decade‐long field experiment of simulated acid deposition in a tropical forest in south China - Yuanliu Hu; Ji Chen; Dafeng Hui; Ying‐Ping Wang; Jianling Li; Jingwen Chen; Guoyin Chen; Yiren Zhu; Leiyi Zhang; Deqiang Zhang; Qi Deng (Global Change Biology, 2022)
South China has been experiencing very high rate of acid deposition and severe soil acidification in recent decades, which has been proposed to exacerbate the regional ecosystem phosphorus (P) limitation. We conducted a 10‐year field experiment of simulated acid deposition to examine how acidification impacts seasonal changes of different soil P fractions in a tropical forest with highly acidic soils in south China. As expected, acid addition significantly increased occluded P pool but reduced the other more labile P pools in the dry season. In the wet season, however, acid addition did not change microbial P, soluble P and labile organic P pools. Acid addition significantly increased exchangeable Al 3+ and Fe 3+ and the activation of Fe oxides in both seasons. Different from the decline of microbial abundance in the dry season, acid addition increased ectomycorrhizal fungi and its ratio to arbuscular mycorrhiza fungi in the wet season, which significantly stimulated phosphomonoesterase activities and likely promoted the dissolution of occluded P. Our results suggest that, even in already highly acidic soils, the acidification‐induced P limitation could be alleviated by stimulating ectomycorrhizal fungi and phosphomonoesterase activities. The differential responses and microbial controls of seasonal soil P transformation revealed here should be implemented into ecosystem biogeochemical model for predicting plant productivity under future acid deposition scenarios.

Study on Salicylanilide Analogue for Antioxidant Activity and Melanosis Prevention in Chinese White Shrimp ( Fenneropenaeus chinensis ) - Hua Fang; Mengyu Li; Hui Chen; Jun Chen; Zhuan Hong; Weizhu Chen; Meijuan Fang (Journal of Aquatic Food Product Technology, 2022)

Framework for Automatic Coral Reef Extraction Using Sentinel-2 Image Time Series - Qizhi Zhuang; Jian Zhang; Liang Cheng; Hui Chen; Yanruo Song; Song Chen; Sensen Chu; Shengkun Dongye; Manchun Li (Marine Geodesy, 2022)

Phenolic compounds from the sclerotia of Inonotus obliquus - Yan-Mei Wei; Li Yang; Wen-Li Mei; Hui-Qin Chen; Cai-Hong Cai; Wei Li; Wen-Hua Dong; Zhi-Bao Chen; Hao-Fu Dai (Natural Product Research, 2022)

Long-term fertilization effects on soil biotic communities are mediated by plant diversity in a Tibetan alpine meadow - Peng Wang; Fei Yang; Xiaoyun Chen; Junyong Li; Xianhui Zhou; Hui Guo (Plant and Soil, 2022)

Ventromedial Thalamus-Projecting DCN Neurons Modulate Associative Sensorimotor Responses in Mice - Jie Zhang; Hao Chen; Li-Bin Zhang; Rong-Rong Li; Bin Wang; Qian-Hui Zhang; Liu-Xia Tong; Wei-Wei Zhang; Zhong-Xiang Yao; Bo Hu (Neuroscience Bulletin, 2022)

Metagenomic analysis reveals wide distribution of phototrophic bacteria in hydrothermal vents on the ultraslow-spreading Southwest Indian Ridge - Hong Chen; Deng Hui Li; Ai Jun Jiang; Xue Gong Li; Shi Jun Wu; Jian Wei Chen; Meng Jie Qu; Xiao Qing Qi; Jie Dai; Rui Zhao; Wei-Jia Zhang; Shan Shan Liu; et al. (Marine Life Science & Technology, 2022)

Physicochemical properties, molecular structure, antioxidant activity, and biological function of extracellular melanin from Ascosphaera apis - Zhi Li; Hui Heng; Qiqian Qin; Lanchun Chen; Yuedi Wang; Zeyang Zhou (Journal of Zhejiang University-SCIENCE B, 2022)

Non-equilibrium seepage characteristics and stability analysis of macroporous soil slope under water level changes - Yun Que; Hui Ding; Zhenliang Jiang; Xian Chen; Shanghui Li; Anthony Kwan Leung (Arabian Journal of Geosciences, 2022)

Correction to: Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats - Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; Bo-Yuan Fan; Ming-Ming Zhang; Tao Chen; Hui Li; Yang Bai; Yun-Qing Li (Neuroscience Bulletin, 2022)
Central sensitization is essential in maintaining chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. Here, we examined the role of the anterior cingulate cortex (ACC) in the pathogenesis of abdominal hyperalgesia in a rat model of CP induced by intraductal administration of trinitrobenzene sulfonic acid (TNBS). TNBS treatment resulted in long-term abdominal hyperalgesia and anxiety in rats. Morphological data indicated that painful CP induced a significant increase in FOS-expressing neurons in the nucleus tractus solitarii (NTS) and ACC, and some FOS-expressing neurons in the NTS projected to the ACC. In addition, a larger portion of ascending fibers from the NTS innervated pyramidal neurons, the neural subpopulation primarily expressing FOS under the condition of painful CP, rather than GABAergic neurons within the ACC. CP rats showed increased expression of vesicular glutamate transporter 1, and increased membrane trafficking and phosphorylation of the N -methyl-D-aspartate receptor (NMDAR) subunit NR2B and the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) subunit GluR1 within the ACC. Microinjection of NMDAR and AMPAR antagonists into the ACC to block excitatory synaptic transmission significantly attenuated abdominal hyperalgesia in CP rats, which was similar to the analgesic effect of endomorphins injected into the ACC. Specifically inhibiting the excitability of ACC pyramidal cells via chemogenetics reduced both hyperalgesia and comorbid anxiety, whereas activating these neurons via optogenetics failed to aggravate hyperalgesia and anxiety in CP rats. Taken together, these findings provide neurocircuit, biochemical, and behavioral evidence for involvement of the ACC in hyperalgesia and anxiety in CP rats, as well as novel insights into the cortical modulation of painful CP, and highlights the ACC as a potential target for neuromodulatory interventions in the treatment of painful CP.

Effects of dihydroartemisinin, a metabolite of artemisinin, on colon cancer chemoprevention and adaptive immune regulation - Chong-Zhi Wang; Chunping Wan; Yun Luo; Chun-Feng Zhang; Qi-Hui Zhang; Lina Chen; Zhi Liu; Daniel H. Wang; Mallory Lager; Cang-Hai Li; Ting-Liang Jiang; Lifei Hou; et al. (Molecular Biology Reports, 2022)

Soil phosphorus availability and stoichiometry determine microbial activity and functional diversity of fluvo-aquic soils under long-term fertilization regimes - Wei He; Wenhua Ye; Mingjie Sun; Yaping Li; Manman Chen; Meng Wei; Guoqing Hu; Quangang Yang; Hong Pan; Yanhong Lou; Hui Wang; Yuping Zhuge (Journal of Soils and Sediments, 2022)

Cavin-1 promotes M2 macrophages/microglia polarization via SOCS3 - Wei Huang; Yiyi Hong; Wenjing He; Li Jiang; Wen Deng; Biyan Peng; Fen Tang; Chaolan Shen; Qianqian Lan; Hui Huang; Haibin Zhong; Jian Lv; et al. (Inflammation Research, 2022)

Development and application of novel InDel markers in flax (Linum usitatissimum L.) through whole-genome re-sequencing - Hui Jiang; Gen Pan; Touming Liu; Li Chang; Siqi Huang; Huijuan Tang; Yuan Guo; Yena Wu; Jie Tao; Anguo Chen (Genetic Resources and Crop Evolution, 2022)

Genetic diversity and population structure of Curcuma alismatifolia Gagnep. accessions revealed by SSR markers - Hui-Wen Yu; Ling-Jun Ke; Yi-Lan Xiao; Si-Jia Chen; Yuan-Yuan Li; Qi-Lin Tian; Yun-He Li; Jin-Shui Lin; Luan-Mei Lu (Genetic Resources and Crop Evolution, 2022)

Association between congenital heart defects and maternal manganese and iron concentrations: a case–control study in China - Meixian Wang; Yan Tian; Ping Yu; Nana Li; Ying Deng; Lu Li; Hong Kang; Dapeng Chen; Hui Wang; Zhen Liu; Juan Liang (Environmental Science and Pollution Research, 2022)
To investigate the correlation between maternal manganese and iron concentrations and the risk of CHD among their infant. A multi-center hospital-based case control study was conducted in China. There were 322 cases and 333 controls have been selected from pregnant women who received prenatal examinations. Correlations between CHDs and maternal manganese and iron concentrations were estimated by conditional logistic regression. Moreover, the interaction between manganese and iron on CHDs was analyzed. Compared with the controls, mothers whose hair manganese concentration was 3.01 μg/g or more were more likely to have a child with CHD than those with a lower concentration. The adjusted OR was 2.68 (95%CI = 1.44–4.99). The results suggested that mothers whose iron content was 52.95 μg/g or more had a significantly higher risk of having a child with CHD ( aOR = 2.87, 95%CI = 1.54–5.37). No interaction between maternal manganese and iron concentrations was observed in the multiplicative or additive model. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD ( OR = 7.02). Women with excessive manganese concentrations have a significantly increased risk of having offspring with CHDs. The high maternal iron status also correlates with CHDs. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD.

Effect of SpyTag/SpyCatcher cyclization on stability and refolding of green fluorescent protein - Haiyan Song; Yue Wang; Wenge Dong; Qiwei Chen; Hongxu Sun; Hui Peng; Ren Li; Yanhong Chang; Hui Luo (Biotechnology Letters, 2022)

Development of MEMS directed evolution strategy for multiplied throughput and convergent evolution of cytochrome P450 enzymes - Li Ma; Fengwei Li; Xingwang Zhang; Hui Chen; Qian Huang; Jing Su; Xiaohui Liu; Tianjian Sun; Bo Fang; Kun Liu; Dandan Tang; Dalei Wu; et al. (Science China Life Sciences, 2022)

Genetic loci and responsible genes for pod and seed traits under diverse environments via linkage mapping analysis in soybean [Glycine max (L.) Merr.] - Shiliang Chen; Yaqian Sun; Zhenqi Shao; Jiahao Chu; Wenlong Li; Youbin Kong; Hui Du; Xihuan Li; Caiying Zhang (Genetic Resources and Crop Evolution, 2022)

Association of long-term exposure to ambient air pollution with the number of tuberculosis cases notified: a time-series study in Hong Kong - Man Xu; Ping Hu; Ruoling Chen; Bing Liu; Hongying Chen; Jian Hou; Li ke; Jiao Huang; Hairong Ren; Hui Hu (Environmental Science and Pollution Research, 2022)

Photocatalytic degradation of imidacloprid by optimized Bi2WO6/NH2-MIL-88B(Fe) composite under visible light - Mao-Long Chen; Tian-Hui Lu; Shan-Shan Li; Li Wen; Zhou Xu; Yun-Hui Cheng (Environmental Science and Pollution Research, 2022)

A controversy on the three fundamental growth determinants in selected CEE countries - Hui-Yun Li; Shah Saud; Abdul Haseeb; Muhammad Wasif Zafar; Songsheng Chen; Sumayya (Environmental Science and Pollution Research, 2022)

A comprehensive exploration on the health risk quantification assessment of soil potentially toxic elements from different sources around large-scale smelting area - Chang-Chen Huang; Li-Mei Cai; Yao-Hui Xu; Luo Jie; Lai-Guo Chen; Guo-Cheng Hu; Hui-Hao Jiang; Xu-Bang Xu; Jing-Xian Mei (Environmental Monitoring and Assessment, 2022)

Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components - Tingting Lin; Jiaqi Tao; Ying Chen; Yitong Zhang; Fenglan Li; Yutong Zhang; Xueqing Han; Zihui Zhao; Guiyan Liu; Hui Li (Biological Trace Element Research, 2022)

Cultivation of arbuscular mycorrhizal Broussonetia papyrifera seedlings by planting the mycorrhizal nurse plant downwards - Zhihao Wang; Jingwei Liang; Yuxuan Kuang; Xue Li; Hui Chen; Ming Tang; Wentao Hu (Mycorrhiza, 2022)

Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Four new prenylflavonol glycosides from the leaves of Cyclocarya paliurus - Zi-Jun Ye; Hui-Hui Sun; Zu-Hui Chen; Jian-Ping Wu; Jing Li; Hui Zhu; Lu-Lu Huang; Xi-Wen Chang; Sai-Yu Ou; Wen-Xuan Wang; Xiao-Ai He; Gang-Zhi Zhu; et al. (Natural Product Research, 2022)

Seasonality and Sex-Biased Fluctuation of Birth Weight in Tibetan Populations - Yaoxi He; Jun Li; Tian Yue; Wangshan Zheng; Yongbo Guo; Hui Zhang; Li Chen; Chunxia Li; Hongyan Li; Chaoying Cui; Ouzhuluobu; Xuebin Qi; et al. (Phenomics, 2022)

Characteristics of typical air pollutants in a valley-basin city in South China - Chu Wu; Jibing Li; Xiaoping Lin; Yangzhi Mo; Hui Zhang; Zhihui Liao; Yu Wang; Duohong Chen (Meteorology and Atmospheric Physics, 2022)

Identification and bioinformatics analysis of differentially expressed milk exosomal microRNAs in milk exosomes of heat-stressed Holstein cows - Yue Wang; Jian Fang; Han-Fang Zeng; Ji-Feng Zhong; Hui-Xia Li; Kun-Lin Chen (Functional & Integrative Genomics, 2022)

East Asian summer monsoon changes in subtropical China since late Pleistocene: Evidence from the Ailuropoda-Stegodon fauna - Zhi-wen Li; Li Sun; Bao-sheng Li; Feng-nian Wang; Ding-ding Du; You-gui Song; Hui-Juan Zhang; Liu-qin Chen; Dan Xu (Journal of Mountain Science, 2022)

Responses and feedback of litter properties and soil mesofauna to herbaceous plants expansion into the alpine tundra on Changbai Mountain, China - Ying-jie Zhang; Ying-hua Jin; Jia-wei Xu; Hong-shi He; Yan Tao; Zhi-peng Yang; Jing Zhao; Yin-xia Diao; Chen-hui Sun; Mai-He Li (Journal of Mountain Science, 2022)

Effects of Silver Nanoparticles on Denitrification and Associated N2O Release in Estuarine and Marine Sediments - Pengfei Sun; Kuiran Li; Shaokui Yi; Hui Li; Xi Chen (Journal of Ocean University of China, 2022)

Multiple-Stage Mineralization in the Huayangchuan U−REE−Mo−Cu−Fe Ore Belt of the Qinling Orogen, Central China: Geological and Re−Os Geochronological Constraints - Hongjun Jiang; Chunsi Yang; Dequan Wang; Hui Zheng; Jie Li; Huayong Chen (Journal of Earth Science, 2022)
The Huayangchuan ore belt is located in the western segment of Xiaoqinling Orogen in the southern margin of the North China Craton (NCC), and hosts voluminous magmatism and significant U−REE−Mo−Cu−Fe polymetallic mineralization. However, geochronological framework of the various mineralization phases in this region is poorly understood. Here, we present new Re−Os isochron ages on magnetite from the Caotan Fe deposit (2 675 ± 410 Ma, MSWD = 0.55), and on pyrite from the Jialu REE deposit (2 127 ± 280 Ma, MSWD = 1.9) and Yuejiawa Cu deposit (418 ± 23 Ma, MSWD = 11.5), and Re−Os weighted average model age on pyrite from the Taoyuan Mo−U deposit (235 ± 14 Ma, MSWD = 0.17). These ages, combined with regional geology and mineralization ages from other deposits, suggest that mineralization in the Huayangchuan ore belt lasted from the Neoarchean to the Late Mesozoic. The mineralization corresponds to regional tectono-magmatic events, including the Neoar-chean alkali magmatism (REE mineralization), Paleoproterozoic plagioclase-amphibolite emplacement (Fe mineralization), Paleoproterozoic pegmatite magmatism (U mineralization), Paleozoic Shangdan oceanic slab subduction-related arc magmatism (Cu mineralization), Early Mesozoic Paleo-Tethys Ocean subduction-related arc magmatism (Mo−U mineralization), and Late Mesozoic Paleo-Pacific oceanic plate subduction direction change-related Mo(-Pb) mineralization. We proposed that the Huayang-chuan ore belt has undergone prolonged metallogenic evolution, and the magmatism and associated mineralization were controlled by regional geodynamic events.

Infectivity and antigenicity of pseudoviruses with high-frequency mutations of SARS-CoV-2 identified in Portugal - Hai-xin Wang; Li Zhang; Zi-teng Liang; Jian-hui Nie; Jia-jing Wu; Qian-qian Li; Ru-xia Ding; Yue Zhang; Guo-qing Chen; You-chun Wang; Hui-guo Wang; Wei-jin Huang (Archives of Virology, 2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a major impact on global human health. During the spread of SARS-CoV-2, weakened host immunity and the use of vaccines with low efficacy may result in the development of more-virulent strains or strains with resistance to existing vaccines and antibodies. The prevalence of SARS-CoV-2 mutant strains differs between regions, and this variation may have an impact on the effectiveness of vaccines. In this study, an epidemiological investigation of SARS-CoV-2 in Portugal was performed, and the VSV-ΔG-G* pseudovirus system was used to construct 12 spike protein epidemic mutants, D614G, A222V+D614G, B.1.1.7, S477N+D614G, P1162R+D614G+A222V, D839Y+D614G, L176F+D614G, B.1.1.7+L216F, B.1.1.7+M740V, B.1.258, B.1.258+L1063F, and B.1.258+N751Y. The mutant pseudoviruses were used to infect four susceptible cell lines (Huh7, hACE2-293T-293T, Vero, and LLC-MK2) and 14 cell lines overexpressing ACE2 from different species. Mutant strains did not show increased infectivity or cross-species transmission. Neutralization activity against these pseudoviruses was evaluated using mouse serum and 11 monoclonal antibodies. The neutralizing activity of immunized mouse serum was not significantly reduced with the mutant strains, but the mutant strains from Portugal could evade nine of the 11 monoclonal antibodies tested. Neutralization resistance was mainly caused by the mutations S477N, N439K, and N501Y in the spike-receptor binding domain. These findings emphasize the importance of SARS-CoV-2 mutation tracking in different regions for epidemic prevention and control.

Analysis of Pipeline Deformation Caused by Shield Tunnel Excavation that Obliquely Crosses Existing Pipelines - Sheng-Wu Zhao; Xiao-Li Li; Xin Li; Li-Guang Chen; Tong Li; Suo-Hui Li; Yu Bai (Arabian Journal of Geosciences, 2022)

Two new threonine-containing metabolites from fungus Curvularia inaequalis strain HS-FG-257 - Shao-Yong Zhang; Jian-Song Li; Hui Zhang; Huan Qi; Rui-Jun Wang; Chou-Fei Wu; Li-Qin Zhang; An-Liang Chen; Ji-Dong Wang; Zhi-Kui Hao (Natural Product Research, 2022)

SYL3-k increases style length and yield of F1 seeds via enhancement of endogenous GA4 content in Oryza sativa L. pistils - Xiaojing Dang; Yuanqing Zhang; Yulong Li; Siqi Chen; Erbao Liu; Bingjie Fang; Qiangming Liu; Dong She; Zhiyao Dong; Zhilan Fan; Dalu Li; Hui Wang; et al. (Theoretical and Applied Genetics, 2022)
Key message SYL3-k allele increases the outcrossing rate of male sterile line and the yield of hybrid F 1 seeds via enhancement of endogenous GA 4 content in Oryza sativa L. pistils. The change in style length might be an adaptation of rice cultivation from south to north in the northern hemisphere. Abstract The style length (SYL) in rice is one of the major factors influencing the stigma exertion, which affects the outcross rate of male sterile line and the yield of hybrid F 1 seeds. However, the biological mechanisms underlying SYL elongation remain elusive. Here, we report a map-based cloning and characterisation of the allele qSYL3-k . The qSYL3-k allele encodes a MADS-box family transcription factor, and it is expressed in various rice organs. The qSYL3-k allele increases SYL via the elongation of cell length in the style, which is associated with a higher GA 4 content in the pistil. The expression level of OsGA3ox2 in pistils with qSYL3-k alleles is significantly higher than that in pistils with qSYL3-n allele on the same genome background of Nipponbare. The yield of F 1 seeds harvested from plants with 7001S SYL3−k alleles was 16% higher than that from plants with 7001S SYL3−n allele. The sequence data at the qSYL3 locus in 136 accessions showed that alleles containing the haplotypes qSYL3 AA , qSYL3 AG , and qSYL3 GA increased SYL, whereas those containing the haplotype qSYL3 GG decreased it. The frequency of the haplotype qSYL3 GG increases gradually from the south to north in the northern hemisphere. These findings will facilitate improvement in SYL and yield of F 1 seeds henceforward.

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma - Cheng Wang; Mingtao Huang; Congcong Chen; Yuancheng Li; Na Qin; Zijian Ma; Jingyi Fan; Linnan Gong; Hui Zeng; Liu Yang; Xianfeng Xu; Jun Zhou; et al. (Science China Life Sciences, 2022)

Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling - Qingxiu Yao; Hui Wang; Hengchao Chen; Zhuangzhuang Li; Yumeng Jiang; Zhipeng Li; Jiping Wang; Yazhi Xing; Feng Liu; Dongzhen Yu; Shankai Yin (Molecular Neurobiology, 2022)
Hearing loss is the most common human sensory deficit. Hearing relies on stereocilia, inserted into the cuticular plate of hair cells (HCs), where they play an important role in the perception of sound and its transmission. Although numerous genes have been associated with hearing loss, the function of many hair cell genes has yet to be elucidated. Herein, we focused on nonerythroid spectrin αII (SPTAN1), abundant in the cuticular plate, surrounding the rootlets of stereocilia and along the plasma membrane. Interestingly, mice with HC-specific Sptan1 knockout exhibited rapid deafness, abnormal formation of stereocilia and cuticular plates, and loss of HCs from middle and apical turns of the cochlea during early postnatal stages. Additionally, Sptan1 deficiency led to the decreased spreading of House Ear Institute-Organ of Corti 1 cells, and induced abnormal formation of focal adhesions and integrin signaling in mouse HCs. Altogether, our findings highlight SPTAN1 as a critical molecule for HC stereocilia morphology and auditory function via regulation of focal adhesion signaling.

Effects of soil cadmium exposure on physio-ecological characteristics of Bletilla striata - Qin Xu; Jihong Qin; Hui Sun; Xiaoqin Wang; Wenqing Chen; Zhi Li (Environmental Science and Pollution Research, 2022)

Study on metal binding capacity of the freshwater crab Sinopotamon henanense’s recombinant copper specific binding metallothionein expressed in Escherichia coli - Lu Wang; Hui Zhen Yang; Wen Li Ma; Chien Min Chen; Lan Wang (Ecotoxicology, 2022)

Transcriptome analyses of the Chinese white pine beetle-fungal symbiont Leptographium qinlingensis under terpene stress or growth on host pine sawdust - Lulu Dai; Hui Li; Jie Zheng; Hui Chen (Symbiosis, 2022)

Geochemical characteristics and source of crude oil in the Shenhu uplift, Pearl River Mouth Basin, South China Sea - Xiaoyan Fu; Shijia Chen; Xin He; Junjun You; Hui Li; Mingzhu Lei (Arabian Journal of Geosciences, 2022)

Identification of the vertical sealing of faults by geochemical methods—taking the Zhu-3 sub-basin of the Pearl River Mouth Basin as an example - Xiaoyan Fu; Shijia Chen; Junjun You; Hui Li; Mingzhu Lei (Arabian Journal of Geosciences, 2022)

Not out of the woods yet: Signatures of the prolonged negative genetic consequences of a population bottleneck in a rapidly re‐expanding wader, the black‐faced spoonbill Platalea minor - Shou‐Hsien Li; Yang Liu; Chia‐Fen Yeh; Yuchen Fu; Carol K. L. Yeung; Chun‐Cheng Lee; Chi‐Cheng Chiu; Tung Hui Kuo; Fang‐Tse Chan; Yu‐Chia Chen; Wen‐Ya Ko; Cheng‐Te Yao (Molecular Ecology, 2022)
The long‐term persistence of a population which has suffered a bottleneck partly depends on how historical demographic dynamics impacted its genetic diversity and the accumulation of deleterious mutations. Here we provide genomic evidence for the genetic effect of a recent population bottleneck in the endangered black‐faced spoonbill ( Platalea minor ) after its rapid population recovery. Our data suggest that the bird's effective population size, N e , had been relatively stable (7500–9000) since 22,000 years ago; however, a recent brief yet severe bottleneck ( N e = 20) which we here estimated to occur around the 1940s wiped out >99% of its historical N e in roughly three generations. Despite a >15‐fold population recovery since 1988, we found that black‐faced spoonbill population has higher levels of inbreeding (7.4 times more runs of homozygosity) than its sister species, the royal spoonbill ( P. regia ), which is not thought to have undergone a marked population contraction. Although the two spoonbills have similar levels of genome‐wide genetic diversity, our results suggest that selection on more genes was relaxed in the black‐faced spoonbill; moreover individual black‐faced spoonbills carry more putatively deleterious mutations (Grantham's score > 50), and may therefore express more deleterious phenotypic effects than royal spoonbills. Here we demonstrate the value of using genomic indices to monitor levels of genetic erosion, inbreeding and mutation load in species with conservation concerns. To mitigate the prolonged negative genetic effect of a population bottleneck, we recommend that all possible measures should be employed to maintain population growth of a threatened species.

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

Investigation of factors influencing the release of chloropropanols (3-MCPD and 1,3-DCP) from food contact paper - Huai-ning Zhong; Ying Zeng; Dao-yuan Yang; Ze-chun Wu; Dan Li; Hai-xia Sui; Jie Gao; Yan-fen Chen; Ce-Hui Mo (Food Additives & Contaminants: Part A, 2021)

Adsorption of BDE-209 to Polyethylene Microplastics: Effect of Microplastics Property and Metal Ions - Yanfeng Zhu; Xiaoxiao Li; Liping Wang; Nan Hui; Jing Ma; Fu Chen (Water, Air, & Soil Pollution, 2021)

Experimental Study on the Response Characteristics of the Apparent Resistivity of Rock True Triaxial Hydraulic Fracturing - Nan Li; Manyue Yan; Hui Zhao; Peng Chen; Chao Cai; Enyuan Wang; Zhihuai Li (Natural Resources Research, 2021)

Molecular characterization and gene expression analysis of tomato WOX transcription factor family under abiotic stress and phytohormone treatment - Hui Li; Xiaohong Li; Meihua Sun; Shuisen Chen; Hui Ma; Jingwei Lin; Yibo Sun; Ming Zhong (Journal of Plant Biochemistry and Biotechnology, 2021)

Clinical and Molecular Features of POLG-Related Sensory Ataxic Neuropathy with Dysarthria and Ophthalmoparesis - Li-Xi Li; Li-Ting Jiang; You-Gui Pan; Xiao-Long Zhang; Li-Zhen Pan; Zhi-Yu Nie; Yu-Hui Chen; Ling-Jing Jin (Journal of Molecular Neuroscience, 2021)

Predicting circRNA-Disease Associations Based on Deep Matrix Factorization with Multi-source Fusion - Guobo Xie; Hui Chen; Yuping Sun; Guosheng Gu; Zhiyi Lin; Weiming Wang; Jianming Li (Interdisciplinary Sciences: Computational Life Sciences, 2021)

The first third-generation HIV-1 circulating recombinant form (CRF114_0155) identified in central China - Yang Li; Yan Zhang; Hongye Wang; Long Liu; Hui Chen; Shuanhu Zhang; Wenying Wu; Rongge Yang (Archives of Virology, 2021)

Differential effects of altered precipitation regimes on soil carbon cycles in arid versus humid terrestrial ecosystems - Bin Wang; Yali Chen; Yan Li; Hui Zhang; Kai Yue; Xingchang Wang; Yuandan Ma; Jian Chen; Meng Sun; Zhuo Chen; Qiqian Wu (Global Change Biology, 2021)
Changes in precipitation regimes have significant effects on soil carbon (C) cycles; however, these effects may vary in arid versus humid areas. Additionally, the corresponding details of soil C cycles in response to altered precipitation regimes have not been well documented. Here, a meta‐analysis was performed using 845 pairwise observations (control vs. increased or decreased precipitation) from 214 published articles to quantify the responses of the input process of exogenous C, the contents of various forms of C in soil, and the soil‐atmosphere C fluxes relative to increased or decreased precipitation. The results showed that the effects of altered precipitation regimes did not differ between rainfall and snowfall. Increased precipitation significantly enhanced the soil C inputs, pools and outputs by 18.17%, 18.50%, and 21.04%, respectively, while decreased precipitation led to a significant decline in these soil C parameters by 10.18%, 9.96%, and 17.98%, respectively. The effects of increased precipitation on soil C cycles were more significant in arid areas (where mean annual precipitation, MAP

Late Silurian to early Devonian development of the Chingiz accretion arc, West Junggar: insights into accretion arc evolution in the Central Asia Orogenic Belt - Yichao Chen; Ji’En Zhang; Wenjiao Xiao; Renjie Zhou; Shuaihua Song; Zhiyong Zhang; Songjian Ao; Miao Sang; Qian W.L. Zhang; Rui Li; Zhen M.G. Li; Yin Liu; et al. (International Geology Review, 2021)

Theoretical and Numerical Analysis of Blasting Pressure of Cylindrical Shells under Internal Explosive Loading - Zhan-Feng Chen; Hui-Jie Wang; Zhiqian Sang; Wen Wang; He Yang; Wei-Ming Meng; Yu-Xing Li (Journal of Marine Science and Engineering, 2021)
Cylindrical shells are principal structural elements that are used for many purposes, such as offshore, sub-marine, and airborne structures. The nonlinear mechanics model of internal blast loading was established to predict the dynamic blast pressure of cylindrical shells. However, due to the complexity of the nonlinear mechanical model, the solution process is time-consuming. In this study, the nonlinear mechanics model of internal blast loading is linearized, and the dynamic blast pressure of cylindrical shells is solved. First, a mechanical model of cylindrical shells subjected to internal blast loading is proposed. To simplify the calculation, the internal blast loading is reduced to linearly uniform variations. Second, according to the stress function method, the dynamic blast pressure equation of cylindrical shells subjected to blast loading is derived. Third, the calculated results are compared with those of the finite element method (FEM) under different durations of dynamic pressure pulse. Finally, to reduce the errors, the dynamic blast pressure equation is further optimized. The results demonstrate that the optimized equation is in good agreement with the FEM, and is feasible to linearize the internal blast loading of cylindrical shells.

Cytotoxic triterpenoid glycosides from leaves of Cyclocarya paliurus - Hui-Hui Sun; Wen-Yan Lv; Jie Tan; Yu-Cheng Tang; Hui Zhu; Jian-Bo Qu; Jing Li; Jian-Ping Wu; Xi-Wen Chang; Zhi-Chun Yang; Wen-Xuan Wang; Zu-Hui Chen; et al. (Natural Product Research, 2021)

Three new dimeric 2-(2-phenylethyl)chromones from artificial agarwood of Aquilaria sinensis - Pan Xiang; Wen-Hua Dong; Cai-Hong Cai; Wei Li; Li-Man Zhou; Hao-Fu Dai; Hui-Qin Chen; Wen-Li Mei (Natural Product Research, 2021)

Removal of roosters alters the domestic phenotype and microbial and genetic profile of hens - Hai Xiang; Siyu Chen; Hui Zhang; Xu Zhu; Dan Wang; Huagui Liu; Jikun Wang; Tao Yin; Langqing Liu; Minghua Kong; Jian Zhang; Hua Li; et al. (Science China Life Sciences, 2021)

Retraction Note to: Deoxynivalenol-induced alterations in the redox status of HepG2 cells: identification of lipid hydroperoxides, the role of Nrf2-Keap1 signaling, and protective effects of zinc - Wageh Sobhy Darwish; Zhen Chen; Yonghan Li; Hui Tan; Hitoshi Chiba; Shu-Ping Hui (Mycotoxin Research, 2021)

Analysis on improvement effect of subgrade by dynamic compaction - Hui Qi; Chenjun Yang; Chao Hu; Yu Rong; Zhanyong Yao; Hongguang Jiang; Kai Yao; Luchuan Chen; Hui Li; Xianfei Teng (Arabian Journal of Geosciences, 2021)

Simulation of indoor cigarette smoke particles in a ventilated room - Yunfei Song; Quan Yang; Hui Li; Shengnan Shen; Hongbin Chen; Yicang Huang; Guoqing Zhang; Jiayue Wang; Wei Wei (Air Quality, Atmosphere & Health, 2021)

A new ergostane derivative from the leaves of Heynea trijuga Roxburgh - Shou-Bai Liu; Zheng Cui; Hui-Qin Chen; Hao Wang; Wen-Hua Dong; Cai-Hong Cai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Whole-genome resequencing of 240 Gossypium barbadense accessions reveals genetic variation and genes associated with fiber strength and lint percentage - Jingwen Yu; Yixuan Hui; Jinhong Chen; Hurong Yu; Xinpeng Gao; Zhaohui Zhang; Qin Li; Shuijin Zhu; Tianlun Zhao (Theoretical and Applied Genetics, 2021)

Peripheral CD4+ T cell signatures in predicting the responses to anti-PD-1/PD-L1 monotherapy for Chinese advanced non-small cell lung cancer - Liliang Xia; Hui Wang; Mingjiao Sun; Yi Yang; Chengcheng Yao; Sheng He; Huangqi Duan; Weimin Xia; Ruiming Sun; Yaxian Yao; Zhiwei Chen; Qiong Zhao; et al. (Science China Life Sciences, 2021)

Functional analysis of indole 3-hexanoic acid as a novel auxin from Arabidopsis thaliana - Ping Song; Hui Xu; Jixiu Zhang; Huatao Chen; Li Li; Yana Qu; Feng Lin; Qun Zhang (Planta, 2021)

A review of the botany, traditional uses, phytochemistry and pharmacology of Nepeta tenuifolia Briq. - Mingqiu Shan; Yulan Jiang; Yuanyuan Fu; Yongyi Zhou; Zhihui Lu; Sheng Yu; Hui Yan; Chanchan Liu; Peidong Chen; Beihua Bao; Li Zhang; Qinan Wu (Phytochemistry Reviews, 2021)

Design and Evaluation of Multiplex One-Step Reverse Transcription PCR–Dipstick Chromatography Method for the Analysis of Seven Respiratory Pathogens - Li Luo; Qianming Chen; Sheng Qin; Qiang Luo; Zhenjie Liu; Qiong Li; Shuilan Zheng; Xianzhang Huang; Peifeng Ke; Xiangsheng Yang; Hui Xiao; Ning Xu (Current Microbiology, 2021)

High-K calc-alkaline to shoshonitic intrusions in SE Tibet: implications for metasomatized lithospheric mantle beneath an active continental margin - Ren-Zhi Zhu; Ewa Słaby; Shao-Cong Lai; Li-Hui Chen; Jiangfeng Qin; Chao Zhang; Shaowei Zhao; Fangyi Zhang; Wen-hang Liu; Mike Fowler (Contributions to Mineralogy and Petrology, 2021)

An Investigation of Toxic Metal Levels (Pb, Cd, Cr, As, Hg) in Dried Porphyra and Laminaria Collected from Coastal Cities, China - Yan Chen; Yong-tao Liu; Fu-hua Wang; Dian Wen; Hui Yang; Xiao-li Zhao (Biological Trace Element Research, 2021)

Performance evaluation of the filters with adaptive factor and fading factor for GNSS/INS integrated systems - Chen Jiang; Shubi Zhang; Hui Li; Zhen Li (GPS Solutions, 2021)

Interactive effects of nutrient availability, fluctuating supply, and plant parasitism on the post-invasion success of Bidens pilosa - Fang-Lei Gao; Qiao-Sheng He; Ru-Qian Xie; Jia-Hui Hou; Chen-Lu Shi; Jun-Min Li; Fei-Hai Yu (Biological Invasions, 2021)

Non-consumptive effects of Encarsia formosa on the reproduction and metabolism of the whitefly Bemisia tabaci - Ze-Yun Fan; Zhan-Peng Zhu; Jing Peng; Xin-Yi Chen; Zi-Tong Lu; Hui-Peng Pan; Bao-Li Qiu (BioControl, 2021)

Sandaracinobacteroides hominis gen. nov., sp. nov., isolated from human skin - Ping-Hua Qu; Hai-Min Luo; Jun-Hui Feng; Song Li; Cha Chen; Lei Dong; Yu-Zhen Ming; Wen-Jun Li; Ying Lin (Archives of Microbiology, 2021)

Ectobacillus aegiceratis sp. nov., a novel bacterium isolated from branch of Aegiceras corniculatum - Xiao-Hui Chen; Xiao-Rui Yan; Zi-Hao Huang; Ming-Sheng Chen; Li Tuo (Antonie van Leeuwenhoek, 2021)

Jiella mangrovi sp. nov., a novel endophytic bacterium isolated from leaf of Rhizophora stylosa - Ming-Sheng Chen; Fei-Na Li; Xiao-Hui Chen; Zi-Hao Huang; Xiao-Rui Yan; Li Tuo (Antonie van Leeuwenhoek, 2021)

Experimental study on integrated and autonomous conductivity-temperature-depth (CTD) sensor applied for underwater glider - Bin Lv; Hai-lin Liu; Yi-fan Hu; Cheng-xuan Wu; Jie Liu; Hai-jing He; Jie Chen; Jian Yuan; Zhao-wen Zhang; Lin Cao; Hui Li (Marine Georesources & Geotechnology, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

A Frameshift Variant in the SEMA6B Gene Causes Global Developmental Delay and Febrile Seizures - Li Shu; Yuchen Xu; Qi Tian; Yuanyuan Chen; Yaqin Wang; Hui Xi; Hua Wang; Neng Xiao; Xiao Mao (Neuroscience Bulletin, 2021)

Nutrient Uptake and Distribution in Mycorrhizal Cuttings of Populus × canadensis ‘Neva’ Under Drought Stress - Li Li; Haoqiang Zhang; Ming Tang; Hui Chen (Journal of Soil Science and Plant Nutrition, 2021)

Syntheses, Structures and Luminescent Properties of Eu- and Tb-MOFs with 3,5-Pyridinedicarboxylate and 1,2-Benzenedicarboxylate - Hongsheng Wang; Shichao Wang; Hui Li; Xinhua Chen (Journal of Fluorescence, 2021)

Biodegradation of Di-n-butyl phthalate in rhizosphere and growth-promoting effect of Cucumis sativus Linn. by a novel Pseudomonas sp. DNB-S1 - Shuqin Li; Lei Wang; Ying Li; Fuxin Huang; Hui Yu; Ying Zhang; Rui Li; Zhaobo Chen; Ningrui Wei; Zhengzhe Yu (Ecotoxicology, 2021)

An experimental study on cutting tool hardness optimization for shield TBMs during dense fine silty sand ground tunneling - Xiao-Ping Zhang; Shao-Hui Tang; Quan-Sheng Liu; Xin-Bin Tu; Peng Chen; Fang-Yi Li (Bulletin of Engineering Geology and the Environment, 2021)

Baicalin attenuates adriamycin-induced nephrotic syndrome by regulating fibrosis procession and inflammatory reaction - Ning Tan; Chen-Xia Sun; Hui-Jun Zhu; De-Yu Li; Sheng-Guang Huang; Shou-Di He (Genes & Genomics, 2021)

3D Step-by-step inversion strategy for audio magnetotellurics data based on unstructured mesh - San Cheng; Zhi-Yong Zhang; Feng Zhou; Man Li; Hui Chen; Fu-Sheng Shi; Lin-Pin Huang; Yong Li (Applied Geophysics, 2021)

Taxonomic description of Pseudomonas rhizovicinus sp. nov., isolated from the rhizosphere of a desert shrub Haloxylon ammodendron - Ao-Lei He; Hui-Ru Li; Hui-Ping Li; Jing-Yi Gou; Jia Chen; Qi Zhao; Jin-Lin Zhang (Antonie van Leeuwenhoek, 2021)

Phycicoccus avicenniae sp. nov., a novel endophytic actinomycete isolated from a branch of Avicennia mariana - Ming-Sheng Chen; Xiao-Hui Chen; Zi-Hao Huang; Xiao-Rui Yan; Li Tuo (Antonie van Leeuwenhoek, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

CsKTN1 for a katanin p60 subunit is associated with the regulation of fruit elongation in cucumber (Cucumis sativus L.) - Hui Wang; Jing Sun; Fan Yang; Yiqun Weng; Peng Chen; Shengli Du; Aimin Wei; Yuhong Li (Theoretical and Applied Genetics, 2021)

Hippocampal Interneurons are Required for Trace Eyeblink Conditioning in Mice - Wei-Wei Zhang; Rong-Rong Li; Jie Zhang; Jie Yan; Qian-Hui Zhang; Zhi-An Hu; Bo Hu; Zhong-Xiang Yao; Hao Chen (Neuroscience Bulletin, 2021)
While the hippocampus has been implicated in supporting the association among time-separated events, the underlying cellular mechanisms have not been fully clarified. Here, we combined in vivo multi-channel recording and optogenetics to investigate the activity of hippocampal interneurons in freely-moving mice performing a trace eyeblink conditioning (tEBC) task. We found that the hippocampal interneurons exhibited conditioned stimulus (CS)-evoked sustained activity, which predicted the performance of conditioned eyeblink responses (CRs) in the early acquisition of the tEBC. Consistent with this, greater proportions of hippocampal pyramidal cells showed CS-evoked decreased activity in the early acquisition of the tEBC. Moreover, optogenetic suppression of the sustained activity in hippocampal interneurons severely impaired acquisition of the tEBC. In contrast, suppression of the sustained activity of hippocampal interneurons had no effect on the performance of well-learned CRs. Our findings highlight the role of hippocampal interneurons in the tEBC, and point to a potential cellular mechanism subserving associative learning.

LncRNA TUG1 exhibits pro-fibrosis activity in hypertrophic scar through TAK1/YAP/TAZ pathway via miR-27b-3p - Xian-Min Li; Wen-Yuan Yu; Qi Chen; Hui-Ru Zhuang; Su-Yue Gao; Tian-Lan Zhao (Molecular and Cellular Biochemistry, 2021)

Three new 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones and one new dimeric 2-(2-phenylethyl)chromone from agarwood of Aquilaria crassna Pierre ex Lecomte in Laos - Yang-Mei Zhao; Li Yang; Fan-Dong Kong; Wen-Hua Dong; Wei Li; Hui-Qin Chen; Hao Wang; Cai-Hong Cai; Cui-Juan Gai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Two new flavonoid glucosides from the fruits of Sinopodophyllum hexandrum - Yan-Jun Sun; Hao-Jie Chen; Gui-Min Xue; Hui Chen; Yan-Li Zhang; Meng Li; Kun Du; Jun-Min Wang; Wei-Sheng Feng (Natural Product Research, 2021)

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

Distribution, source, and ecological risk assessment of potentially toxic elements in surface sediments from Qingfeng River, Hunan, China - Zhuo Chen; Shunhong Huang; Liang Chen; Bairui Cheng; Mengfei Li; Hui Huang (Journal of Soils and Sediments, 2021)

Transforming growth factor β as a possible independent factor in chronic hepatitis B - Ming-hui Li; Yao Lu; Fang-fang Sun; Qi-qi Chen; Lu Zhang; Hui-hui Lu; Zhan Zeng; Wei Yi; Yao Xie (Archives of Virology, 2021)

Cysteiniphilum marinum sp. nov., isolated from coastal seawater - Hai-Min Luo; Jun-Hui Feng; Liang-Hui Li; Meng-Meng Li; Ru-Qin Liu; Fu Chen; Ying Lin; Wen-Jun Li; Ping-Hua Qu; Min Xiao (Antonie van Leeuwenhoek, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

An Approach to Determine Optimal Bow Configuration of Polar Ships under Combined Ice and Calm-Water Conditions - Hui Li; Yan Feng; Muk Chen Ong; Xin Zhao; Li Zhou (Journal of Marine Science and Engineering, 2021)
Selecting an optimal bow configuration is critical to the preliminary design of polar ships. This paper proposes an approach to determine the optimal bow of polar ships based on present numerical simulation and available published experimental studies. Unlike conventional methods, the present approach integrates both ice resistance and calm-water resistance with the navigating time. A numerical simulation method of an icebreaking vessel going straight ahead in level ice is developed using SPH (smoothed particle hydrodynamics) numerical technique of LS-DYNA. The present numerical results for the ice resistance in level ice are in satisfactory agreement with the available published experimental data. The bow configurations with superior icebreaking capability are obtained by analyzing the sensitivities due to the buttock angle γ, the frame angle β and the waterline angle α. The calm-water resistance is calculated using FVM (finite volume method). Finally, an overall resistance index devised from the ship resistance in ice/water weighted by their corresponding weighted navigation time is proposed. The present approach can be used for evaluating the integrated resistance performance of the polar ships operating in both a water route and ice route.

Wave-Modified Ekman Current Solutions for the Time-Dependent Vertical Eddy Viscosity - Hui Chen; Shaofeng Li; Jinbao Song; Hailun He (Journal of Marine Science and Engineering, 2021)
This study aimed to highlight a general lack of clarity regarding the scale of the temporal averaging implicit in Ekman-type models. Under the assumption of time and depth-dependent eddy viscosity, we present an analytical Fourier series solution for a wave-modified Ekman model. The depth dependence of eddy viscosity is based on the K-Profile Parameterization (KPP) scheme. The solution reproduces major characteristics of diurnal variation in ocean velocity and shear. Results show that the time variability in eddy viscosity leads to an enhanced mean current near-surface and a decrease in the effective eddy viscosity, which finally results in an intensified near-surface shear and wakes a low-level jet flow. Rectification values are dominated by the strength of diurnal mixing, and partly due to the nonlinear depth dependence of the eddy viscosity.

Quantitative Proteomics Analysis of Sugarcane Ratoon Crop Chlorosis - Ye-Geng Fan; Rong-Fa Chen; Li-Hang Qiu; Zhong-Feng Zhou; Hui-Wen Zhou; Ji-Guang Wei; Xiu-Peng Song; Ting Luo; Prakash Lakshmanan; Xing Huang; Jian-Ming Wu; Yang-Rui Li (Sugar Tech, 2021)

Lipocalin-2-induced proliferative endoplasmic reticulum stress participates in Kawasaki disease-related pulmonary arterial abnormalities - Zhaoling Shi; Yue Yin; Chen Li; Hui Ding; Nan Mu; Yishi Wang; Shanshan Jin; Heng Ma; Manling Liu; Jie Zhou (Science China Life Sciences, 2021)

Sublethal dose of warfarin induction promotes the accumulation of warfarin resistance in susceptible Norway rats - Xiaohui Ma; Yan Chen; Yaqi Ying; Yuanzhao Geng; Dawei Wang; Ning Li; Xiao-Hui Liu; Ying Song (Journal of Pest Science, 2021)

Serum Progesterone and Testosterone Levels in Schizophrenia Patients at Different Stages of Treatment - Wei Huang; Yong-Hang Li; Shi-Qing Huang; Hui Chen; Zai-Fang Li; Xi-Xi Li; Xue-Song Li; Yong Cheng (Journal of Molecular Neuroscience, 2021)

Genome-Wide Investigation of Major Enzyme-Encoding Genes in the Flavonoid Metabolic Pathway in Tartary Buckwheat (Fagopyrum tataricum) - Yingjun Yao; Lei Sun; WenJing Wu; Shuang Wang; Xin Xiao; MinLun Hu; ChengLei Li; HaiXia Zhao; Hui Chen; Qi Wu (Journal of Molecular Evolution, 2021)

Grid algorithm for large-scale topographic oblique photogrammetry precision enhancement in vegetation coverage areas - Chen Wang; Xiaodi Xu; Liangcheng Yu; Heng Li; Jeffrey Boon Hui Yap (Earth Science Informatics, 2021)

Lipopeptide production by Bacillus atrophaeus strain B44 and its biocontrol efficacy against cotton rhizoctoniosis - Li Chen; Hui Zhang; Sifeng Zhao; Benchun Xiang; Zhaoqun Yao (Biotechnology Letters, 2021)

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

Effect of Zinc Oxide Nanoparticles on Denitrification and Denitrifying Bacteria Communities in Typical Estuarine Sediments - Xi Chen; Zhuangzhuang Xiang; Zhaomeng Ren; Xiao Huang; Hui Li; Pengfei Sun; Jie Bai (Journal of Ocean University of China, 2021)

Brachybacterium halotolerans sp. nov., a halotolerant, endophytic actinomycete isolated from branch of Bruguiera gymnoirhiza - Ming-Sheng Chen; Fei-Na Li; Xiao-Hui Chen; Xiao-Rui Yan; Li Tuo (Antonie van Leeuwenhoek, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Distinct methylome patterns contribute to ecotypic differentiation in the growth of the storage organ of a flowering plant (sacred lotus) - Hui Li; Xingyu Yang; Qingfeng Wang; Jinming Chen; Tao Shi (Molecular Ecology, 2021)
DNA methylation is an epigenetic modification involved in phenotypic diversity, plant development, and environmental responses. However, the mechanisms of DNA methylation underpinning the adaption of lotus ( Nelumbo nucifera ) ecotypes to high and low latitudes remain unsolved, especially adaptive evolution of their storage organs. Tropical and temperate lotus ecotypes have thin and enlarged rhizomes which are adapted to low and high latitudes, respectively. Here, we investigated the DNA methylomes and transcriptomes of rhizomes of the temperate and tropical lotus to address this issue. Compared with that of the tropical lotus, the DNA of the temperate lotus was significantly more hypermethylated, indicating an increase in global DNA methylation in the lotus, with rhizome enlargement. Meanwhile, genes associated with differentially methylated regions in their promoters tended to be differentially expressed between the two ecotypes. Interestingly, the genes with their expression negatively correlated with methylation levels in their promoters and genomic regions displayed significantly higher transposon coverage, while the genes showing a significant positive correlation between expression and methylation showed lesser transposon coverage. Further, we identified that DNA methylation, especially in the promoter region, was significantly correlated with the expression of many starch‐biosynthetic, gibberellin‐, and brassinosteroid‐signalling genes associated with rhizome differentiation. Overall, our study unveiled that distinct global and local methylation patterns between the two lotus ecotypes contribute to their expression differences and adaptive phenotypic divergence of their storage organs, highlighting the role of DNA methylation in shaping the ecotypic differentiation of lotus.

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

Biased allelic expression in tissues of F1 hybrids between tropical and temperate lotus (Nelumbo nuicfera) - Zhiyan Gao; Hui Li; Xingyu Yang; Pingfang Yang; Jinming Chen; Tao Shi (Plant Molecular Biology, 2021)

Spatial prediction of soil calcium carbonate content based on Bayesian maximum entropy using environmental variables - Mei Shan; Shuang Liang; Hongchen Fu; Xiaoli Li; Yu Teng; Jingwen Zhao; Yaxin Liu; Chen Cui; Li Chen; Hai Yu; Shunbang Yu; Yanling Sun; et al. (Nutrient Cycling in Agroecosystems, 2021)

New insights into the fine-scale history of western–eastern admixture of the northwestern Chinese population in the Hexi Corridor via genome-wide genetic legacy - Hongbin Yao; Mengge Wang; Xing Zou; Yingxiang Li; Xiaomin Yang; Ailin Li; Hui-Yuan Yeh; Peixin Wang; Zheng Wang; Jingya Bai; Jianxin Guo; Jinwen Chen; et al. (Molecular Genetics and Genomics, 2021)

Design, synthesis and evaluation of dihydrotriazine derivatives-bearing 5-aryloxypyrazole moieties as antibacterial agents - Tian-Yi Zhang; Chun-Shi Li; Ming-Yue Cui; Xue-Qian Bai; Jiang-Hui Chen; Ze-Wen Song; Bo Feng; Xue-Kun Liu (Molecular Diversity, 2021)

Targeted deletion of HAI-1 increases prostasin proteolysis but decreases matriptase proteolysis in human keratinocytes - Dajun D. Lu; Yayun Gu; Sheng-Wen A. Li; Robert J. Barndt; Shih-Ming Huang; Jehng-Kang Wang; Hui Chen Su; Michael D. Johnson; Chen-Yong Lin (Human Cell, 2021)

Genome sequencing and functional annotation of Bacillus sp. strain BS-Z15 isolated from cotton rhizosphere soil having antagonistic activity against Verticillium dahliae - Zhong-Yi Chen; Xieerwanimu Abuduaini; Nuramina Mamat; Qi-Lin Yang; Meng-Jun Wu; Xin-Rui Lin; Ru Wang; Rong-Rong Lin; Wei-Jun Zeng; Huan-Chen Ning; He-Ping Zhao; Jin-Yu Li; et al. (Archives of Microbiology, 2021)

Human β-Defensin 118 Attenuates Escherichia coli K88–Induced Inflammation and Intestinal Injury in Mice - Qian Lin; Qingqing Fu; Xiang Li; Yuheng Luo; Junqiu Luo; Daiwen Chen; Xiangbing Mao; Bing Yu; Ping Zheng; Zhiqing Huang; Jie Yu; Hui Yan; et al. (Probiotics and Antimicrobial Proteins, 2021)

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

DeepMapi: a Fully Automatic Registration Method for Mesoscopic Optical Brain Images Using Convolutional Neural Networks - Hong Ni; Zhao Feng; Yue Guan; Xueyan Jia; Wu Chen; Tao Jiang; Qiuyuan Zhong; Jing Yuan; Miao Ren; Xiangning Li; Hui Gong; Qingming Luo; et al. (Neuroinformatics, 2021)
The extreme complexity of mammalian brains requires a comprehensive deconstruction of neuroanatomical structures. Scientists normally use a brain stereotactic atlas to determine the locations of neurons and neuronal circuits. However, different brain images are normally not naturally aligned even when they are imaged with the same setup, let alone under the differing resolutions and dataset sizes used in mesoscopic imaging. As a result, it is difficult to achieve high-throughput automatic registration without manual intervention. Here, we propose a deep learning-based registration method called DeepMapi to predict a deformation field used to register mesoscopic optical images to an atlas. We use a self-feedback strategy to address the problem of imbalanced training sets (sampling at a fixed step size in nonuniform brains of structures and deformations) and use a dual-hierarchical network to capture the large and small deformations. By comparing DeepMapi with other registration methods, we demonstrate its superiority over a set of ground truth images, including both optical and MRI images. DeepMapi achieves fully automatic registration of mesoscopic micro-optical images, even macroscopic MRI datasets, in minutes, with an accuracy comparable to those of manual annotations by anatomists.

Gas Flow Characteristics and Optimization of Gas Drainage Borehole Layout in Protective Coal Seam Mining: A Case Study from the Shaqu Coal Mine, Shanxi Province, China - Zhiheng Cheng; Hui Pan; Quanle Zou; Zhenhua Li; Liang Chen; Jialin Cao; Kun Zhang; Yongguo Cui (Natural Resources Research, 2021)

A calculation model of the normal coefficient of restitution based on multi-factor interaction experiments - Zhong-Min Ji; Zhi-Jian Chen; Qing-He Niu; Ting-Hui Wang; Tian-Jun Wang; Tian-Li Chen (Landslides, 2021)

Identification and characterization of CONSTANS-like genes from Curcuma alismatifolia - Yuan-Yuan Li; Xiao-Huang Chen; Hui-Wen Yu; Qi-Lin Tian; Luan-Mei Lu (Horticulture, Environment, and Biotechnology, 2021)

Impact of solar ultraviolet radiation on daily outpatient visits of atopic dermatitis in Shanghai, China - Hui-jing Gu; Li Peng; Wen-cai Jiang; Yi-mei Tan; Guo-jiang Zhou; Hai-dong Kan; Ren-jie Chen; Ying Zou (Environmental Science and Pollution Research, 2021)

Increased depression risk for elderly women with high blood levels of strontium and barium - Jia Lv; Yan-ling Li; Wen-qiang Ren; Rong Li; Jian-rong Chen; Chao Bao; Zhi-ping Du; Shun Feng; Ling Gu; Hui Gao; Kai-yong Liu; Lin-sheng Yang; et al. (Environmental Chemistry Letters, 2021)