Design, synthesis, and biological evaluation of novel 2-acetylphenol-rivastigmine hybrids as potential multifunctional agents for the treatment of Alzheimer’s disease - Cong Deng; Jing Mi; Yi Zhou; Xinjuan Li; Zhengwei Liu; Zhipei Sang; Hui Li (Medicinal Chemistry Research, 2022)

Shear behavior of sliding zone soil of loess landslides via ring shear tests in the South Jingyang Plateau - Rongsen Zhu; Wan-li Xie; Qiqi Liu; Hui Yang; Qiyao Wang (Bulletin of Engineering Geology and the Environment, 2022)
Since the 1970s, a large number of loess collapses and landslides have occurred in the Loess Plateau of China due to water diversion and irrigation projects. A large amount of ancient landslide deposits are accumulated at the foot of the tableland, which is likely to slide again in the case of a rapid increase in short-term rainfall or long-term irrigation. The weak characteristics of the sliding zone soil often become the key factor affecting the revival of old landslides. To explore the effects of water content and shear rate on shear behavior of the sliding zone soil, a series of ring shear tests were conducted on reconstituted loess in the South Jingyang Plateau. Experimental results suggest that under the condition of normal consolidation, the soil sample with the optimum moisture content has the highest shear strength. The increase in the shear rate effectively reduces the strength of the soil. Because of the high shear rate, the pore water that cannot be dissipated and fine particles accumulated at the shear plane form a weak base (slurry making theory), which cannot be easily stopped once the landslides start, leading to high-speed and long-distance landslides. In addition, the changes in the soil particles and pores were observed using a scanning electron microscope (SEM), and the observations were consistent with macroscopic results. From these studies, we come to the conclusion that the motion mechanism of reactivated landslide was associated with the interaction of water content and shear rate, which reduces the shear strength of the displaced materials to a great extent.

Pulmonary Infection Caused by Strongyloides stercoralis - Lingqing Xu; Qianjun He; Linjuan Chen; Jiaxi Lv; Yinxian Tang; Yuzhen Li; Zhongwen Zhang; Weihong Wen; Guoquan Zhong; Hui Liu; Bishi Fu (Acta Parasitologica, 2022)

A systematic review of synthetic tyrosinase inhibitors and their structure-activity relationship - Zhiyun Peng; Guangcheng Wang; Qiao-Hui Zeng; Yufeng Li; Haiquan Liu; Jing Jing Wang; Yong Zhao (Critical Reviews in Food Science and Nutrition, 2022)

Tomato yellow leaf curl virus V3 protein traffics along microfilaments to plasmodesmata to promote virus cell-to-cell movement - Pan Gong; Siwen Zhao; Hui Liu; Zhaoyang Chang; Fangfang Li; Xueping Zhou (Science China Life Sciences, 2022)

The study of schizogenous formation of secretory ducts in Ferula ferulaeoides (Steud.) Korov. - Meng-meng Liu; Yuan-yuan Zhao; Ying Ma; Shuang-shuang Liu; Jia-qi Yao; Ya-ping Chi; Hui-fang Li; Kai Liao; Yun Zhu (Protoplasma, 2022)

Ventromedial Thalamus-Projecting DCN Neurons Modulate Associative Sensorimotor Responses in Mice - Jie Zhang; Hao Chen; Li-Bin Zhang; Rong-Rong Li; Bin Wang; Qian-Hui Zhang; Liu-Xia Tong; Wei-Wei Zhang; Zhong-Xiang Yao; Bo Hu (Neuroscience Bulletin, 2022)

Metagenomic analysis reveals wide distribution of phototrophic bacteria in hydrothermal vents on the ultraslow-spreading Southwest Indian Ridge - Hong Chen; Deng Hui Li; Ai Jun Jiang; Xue Gong Li; Shi Jun Wu; Jian Wei Chen; Meng Jie Qu; Xiao Qing Qi; Jie Dai; Rui Zhao; Wei-Jia Zhang; Shan Shan Liu; et al. (Marine Life Science & Technology, 2022)

Taxonomy and toxin profile of harmful benthic Prorocentrum (Dinophyceae) species from the Xisha Islands, South China Sea - Jian Zou; Qun Li; Hui Liu; Ying Liu; Lifen Huang; Haiyan Wu; Jiangbing Qiu; Hua Zhang; Songhui Lü (Journal of Oceanology and Limnology, 2022)

Spatial conflict simulation of land-use based on human-land-landscape elements intercoordination: a case study in Tianjin, China - Xiangping Liu; Zhen Zhang; Mingxin Li; Yanhua Fu; Yu Hui (Environmental Monitoring and Assessment, 2022)

Correction to: Plastome phylogenomics of Allaeanthus, Broussonetia and Malaisia (Dorstenieae, Moraceae) and the origin of B. × kazinoki - Wen-Hsi Kuo; Shih-Hui Liu; Chiung-Chih Chang; Chia-Lun Hsieh; Yi-Hsuan Li; Takuro Ito; Hyosig Won; Goro Kokubugata; Kuo-Fang Chung (Journal of Plant Research, 2022)

Ecological source identification based on the PSR model framework and structural features: a case study in Tianjin, China - Xiangping Liu; Zhen Zhang; Mingxin Li; Yanhua Fu; Yu Hui (Arabian Journal of Geosciences, 2022)

Two new dammarane-type triterpenoids from the green walnut husks of Juglans mandshurica Maxim - Yuan-Yuan Zhou; Hui-Rui Gao; Hong-Juan Song; Dan-Da Ma; Xiao-Juan Zhang; Yan-Ping Sun; Yan Liu; Xiao-Li Wang; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Rate-Dependent Characteristics of Damage and Roughness Degradation of Three-Dimensional Artificial Joint Surfaces - Hui Shen; Yaqun Liu; Haibo Li; Duohua Wu; Xiang Xia; Bo Liu; Chong Yu (Rock Mechanics and Rock Engineering, 2022)

Effects of dihydroartemisinin, a metabolite of artemisinin, on colon cancer chemoprevention and adaptive immune regulation - Chong-Zhi Wang; Chunping Wan; Yun Luo; Chun-Feng Zhang; Qi-Hui Zhang; Lina Chen; Zhi Liu; Daniel H. Wang; Mallory Lager; Cang-Hai Li; Ting-Liang Jiang; Lifei Hou; et al. (Molecular Biology Reports, 2022)

Deciphering therapeutic options for neurodegenerative diseases: insights from SIRT1 - Ruike Wang; Yingying Wu; Rundong Liu; Mengchen Liu; Qiong Li; Yue Ba; Hui Huang (Journal of Molecular Medicine, 2022)

Development and application of novel InDel markers in flax (Linum usitatissimum L.) through whole-genome re-sequencing - Hui Jiang; Gen Pan; Touming Liu; Li Chang; Siqi Huang; Huijuan Tang; Yuan Guo; Yena Wu; Jie Tao; Anguo Chen (Genetic Resources and Crop Evolution, 2022)

Association between congenital heart defects and maternal manganese and iron concentrations: a case–control study in China - Meixian Wang; Yan Tian; Ping Yu; Nana Li; Ying Deng; Lu Li; Hong Kang; Dapeng Chen; Hui Wang; Zhen Liu; Juan Liang (Environmental Science and Pollution Research, 2022)
To investigate the correlation between maternal manganese and iron concentrations and the risk of CHD among their infant. A multi-center hospital-based case control study was conducted in China. There were 322 cases and 333 controls have been selected from pregnant women who received prenatal examinations. Correlations between CHDs and maternal manganese and iron concentrations were estimated by conditional logistic regression. Moreover, the interaction between manganese and iron on CHDs was analyzed. Compared with the controls, mothers whose hair manganese concentration was 3.01 μg/g or more were more likely to have a child with CHD than those with a lower concentration. The adjusted OR was 2.68 (95%CI = 1.44–4.99). The results suggested that mothers whose iron content was 52.95 μg/g or more had a significantly higher risk of having a child with CHD ( aOR = 2.87, 95%CI = 1.54–5.37). No interaction between maternal manganese and iron concentrations was observed in the multiplicative or additive model. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD ( OR = 7.02). Women with excessive manganese concentrations have a significantly increased risk of having offspring with CHDs. The high maternal iron status also correlates with CHDs. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD.

The Predictability of Ocean Environments that Contributed to the 2020/21 Extreme Cold Events in China: 2020/21 La Niña and 2020 Arctic Sea Ice Loss - Fei Zheng; Ji-Ping Liu; Xiang-Hui Fang; Mi-Rong Song; Chao-Yuan Yang; Yuan Yuan; Ke-Xin Li; Ji Wang; Jiang Zhu (Advances in Atmospheric Sciences, 2022)
Several consecutive extreme cold events impacted China during the first half of winter 2020/21, breaking the low-temperature records in many cities. How to make accurate climate predictions of extreme cold events is still an urgent issue. The synergistic effect of the warm Arctic and cold tropical Pacific has been demonstrated to intensify the intrusions of cold air from polar regions into middle-high latitudes, further influencing the cold conditions in China. However, climate models failed to predict these two ocean environments at expected lead times. Most seasonal climate forecasts only predicted the 2020/21 La Niña after the signal had already become apparent and significantly underestimated the observed Arctic sea ice loss in autumn 2020 with a 1–2 month advancement. In this work, the corresponding physical factors that may help improve the accuracy of seasonal climate predictions are further explored. For the 2020/21 La Niña prediction, through sensitivity experiments involving different atmospheric–oceanic initial conditions, the predominant southeasterly wind anomalies over the equatorial Pacific in spring of 2020 are diagnosed to play an irreplaceable role in triggering this cold event. A reasonable inclusion of atmospheric surface winds into the initialization will help the model predict La Niña development from the early spring of 2020. For predicting the Arctic sea ice loss in autumn 2020, an anomalously cyclonic circulation from the central Arctic Ocean predicted by the model, which swept abnormally hot air over Siberia into the Arctic Ocean, is recognized as an important contributor to successfully predicting the minimum Arctic sea ice extent.

Global divergent trends of algal blooms detected by satellite during 1982–2018 - Chong Fang; Kaishan Song; Hans W Paerl; Pierre‐Andre Jacinthe; Zhidan Wen; Ge Liu; Hui Tao; Xiaofeng Xu; Tiit Kutser; Zongming Wang; Hongtao Duan; Kun Shi; et al. (Global Change Biology, 2022)
Algal blooms (ABs) in inland lakes have caused adverse ecological effects, and health impairment of animals and humans. We used archived Landsat images to examine ABs in lakes (>1 km 2 ) around the globe over a 37‐year time span (1982–2018). Out of the 176032 lakes with area >1 km 2 detected globally, 863 were impacted by ABs, 708 had sufficiently long records to define a trend, and 66% exhibited increasing trends in frequency ratio (FRQR, ratio of the number of ABs events observed in a year in a given lake to the number of available Landsat images for that lake) or area ratio (AR, ratio of annual maximum area covered by ABs observed in a lake to the surface area of that lake), while 34% showed a decreasing trend. Across North America, an intensification of ABs severity was observed for FRQR ( p p p p

Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra) - Li-Chao Pan; Yang-Yang Sun; Xiao-Ling Zhang; Zhen-Yuan Zhu; Chun-Yu Liu; Hui-Qing Sun; Xue-Qing Geng; Wei Jiang; Jia-He Wang (Natural Product Research, 2022)

Development of MEMS directed evolution strategy for multiplied throughput and convergent evolution of cytochrome P450 enzymes - Li Ma; Fengwei Li; Xingwang Zhang; Hui Chen; Qian Huang; Jing Su; Xiaohui Liu; Tianjian Sun; Bo Fang; Kun Liu; Dandan Tang; Dalei Wu; et al. (Science China Life Sciences, 2022)

Identification and Expression Analysis of the SBP-box Gene Family Related to Abiotic Stress in Tea Plant (Camellia sinensis (L.) O. Kuntze) - Rui-Min Teng; Yong-Xin Wang; Hui Li; Hao Liu; Yu Wang; Jing Zhuang (Plant Molecular Biology Reporter, 2022)

Transcriptomic analyses reveal the effect of nitric oxide on the lateral root development and growth of mangrove plant Kandelia obovata - Ming-Yue Wei; Huan Li; You-Hui Zhong; Zhi-Jun Shen; Dong-Na Ma; Chang-Hao Gao; Yi-Ling Liu; Wen-Hua Wang; Jing-Ya Zhang; Yan-Ping You; Hai-Lei Zheng (Plant and Soil, 2022)

Decreased glomalin-related soil protein with nitrogen deposition in a 3-year-old Cunninghamia lanceolata plantation - Shuxian Jia; Xiaofei Liu; Weisheng Lin; Yong Zheng; Jianwei Li; Dafeng Hui; Jianfen Guo (Journal of Soils and Sediments, 2022)

Dissecting four correlated growth period traits using a genome-wide association study approach in soybean - Yanfei Li; Ying-hui Li; Huilong Hong; Yansong Ma; Yongzhe Gu; Zhangxiong Liu; Scott A. Jackson; Li-juan Qiu (Genetic Resources and Crop Evolution, 2022)

Association of long-term exposure to ambient air pollution with the number of tuberculosis cases notified: a time-series study in Hong Kong - Man Xu; Ping Hu; Ruoling Chen; Bing Liu; Hongying Chen; Jian Hou; Li ke; Jiao Huang; Hairong Ren; Hui Hu (Environmental Science and Pollution Research, 2022)

Driving factors of carbon emissions in China’s municipalities: a LMDI approach - Yuanxin Liu; Yajing Jiang; Hui Liu; Bo Li; Jiahai Yuan (Environmental Science and Pollution Research, 2022)

Oxidative stress is involved in the activation of NF-κB signal pathway and immune inflammatory response in grass carp gill induced by cypermethrin and/or sulfamethoxazole - Baoying Li; Yu Wang; Hongjing Zhao; Kai Yin; Yachen Liu; Dongxu Wang; Hui Zong; Mingwei Xing (Environmental Science and Pollution Research, 2022)

Predicting acupuncture efficacy for functional dyspepsia based on routine clinical features: a machine learning study in the framework of predictive, preventive, and personalized medicine - Tao Yin; Hui Zheng; Tingting Ma; Xiaoping Tian; Jing Xu; Ying Li; Lei Lan; Mailan Liu; Ruirui Sun; Yong Tang; Fanrong Liang; Fang Zeng (EPMA Journal, 2022)

Text visualization for geological hazard documents via text mining and natural language processing - Ying Ma; Zhong Xie; Gang Li; Kai Ma; Zhen Huang; Qinjun Qiu; Hui Liu (Earth Science Informatics, 2022)

Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components - Tingting Lin; Jiaqi Tao; Ying Chen; Yitong Zhang; Fenglan Li; Yutong Zhang; Xueqing Han; Zihui Zhao; Guiyan Liu; Hui Li (Biological Trace Element Research, 2022)

Plastome phylogenomics of Allaeanthus, Broussonetia and Malaisia (Dorstenieae, Moraceae) and the origin of B. × kazinoki - Wen-Hsi Kuo; Shih-Hui Liu; Chiung-Chih Chang; Chia-Lun Hsieh; Yi-Hsuan Li; Takuro Ito; Hyosig Won; Goro Kokubugata; Kuo-Fang Chung (Journal of Plant Research, 2022)

Characterization and genomic analysis of a Demerecviridae phage SP76 with lytic multiple-serotypes of Salmonella - Hui Wang; Yun Shen; Pei LI; Yuyi Xiao; Yanxiu Li; Xiapei Hu; Zhuohao Wang; Zile Cheng; Zitong Wang; Qingxin Liu; Si Qin; Xiang Huo; et al. (Archives of Microbiology, 2022)

Heavy metal pollution and risk assessment of farmland soil in eco-tourism resort - Qifa Sun; Zhuoan Sun; Jianheng Wang; Weiguo Xing; Guojie Hao; Zhijie Liu; Tao Liu; Zhonglin Sun; Xuguang Li; Hui Tian; Wei Zhu (Arabian Journal of Geosciences, 2022)

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Discerning the Putative U and V Chromosomes of Saccharina japonica (Phaeophyta) by Cytogenetic Mapping of Sex-Linked Molecular Markers - Yu Du; Peng-Fei Liu; Zhi Li; Qian Zheng; Yan-Hui Bi; Zhi-Gang Zhou (Frontiers in Marine Science, 2022)
Saccharina japonica , an importantly industrial species in brown seaweeds, has a typical alternate life history of heteromorphic generations and UV sex determination system. But up to now, the sex chromosomes, U and V, in this kelp remain to be evidenced cytologically. In the present study, the female-linked (SJ-f_000170 and MSj68-58-2) and male-linked (SJ-13_001840 and MSj68-16-2) molecular markers developed on the basis of Ectocarpus sex-determining regions (SDRs) were selected after PCR amplification and Southern blotting analysis. Mono-color fluorescence in situ hybridization (FISH) to the kelp metaphase chromosomes with each of these confirmed sex-linked markers as a probe indicated that the hybridization signals were confined to either female or male gametophytes exclusively. The shape and size of hybridized chromosomes and the relative location of these sex-linked markers on them suggested that the marked chromosomes in a sex were the same, which was further confirmed by dual-color FISH observations. SJ-f_000170 and SJ-13_001840, corresponding to each sex, were therefore used to map the sporophyte metaphase chromosomes by dual-color FISH technique, and they were hybridized on different chromosomes as expected. The sporophyte metaphase chromosomes as hybridized by SJ-f_000170 and SJ-13_001840 resembled those in either female or male gametophytes, suggesting that they were the putative U and V, respectively, chromosomes in S . japonica . To further demonstrate the reliability of this inference, genomic information of the screened bacterial artificial chromosome (BAC) clones carrying two female-linked markers, for example, from the constructed BAC libraries of the kelp female gametophytes was provided. The insert sequencing of two selected BAC clones revealed that repetitive elements were rich whereas gene density was poor, which was characterized as non-recombining SDR sequences in brown seaweed Ectocarpus sp. and liverwort Marchantia polymorpha . The present study laid a solid foundation for unveiling the mystery of S . japonica sex chromosomes.

Integration Bioprocess of B-Phycoerythrin and Exopolysaccharides Production From Photosynthetic Microalga Porphyridium cruentum - Hao-Chan Yin; Ji-Kang Sui; Tian-Li Han; Tian-Zhong Liu; Hui Wang (Frontiers in Marine Science, 2022)
Red microalga Porphyridium cruentum has great potential for converting CO 2 into high-value bioactive compounds, such as B-phycoerythrin (B-PE) and extracellular polysaccharides or exopolysaccharides (EPS). This study aimed to establish the integration bioprocess of B-PE and EPS production from P. cruentum . First, different kinds of growth medium and CO 2 concentration were assessed indoor in terms of high biomass and B-PE and EPS contents. As follows, P. cruentum cells were outdoor scale-up cultured in 700 L pressurized tubular reactors for 9 days till the biomass reached 0.85 g/L and then separated from supernatants via centrifugation. Three different methods were adopted to extract phycobiliproteins, and the highest PE contents were extracted from cells by repeated freeze-thawing treatment along with the optimization of significant variables, and finally, 7.99 mg/L B-PE (16,500 Da) with a purity index of 0.82 was obtained. Moreover, analysis of physicochemical properties of EPS extracted from P. cruentum showed that the sulfate content was 14.85% and the uronic acid content was 9.36%.

Automatic White Blood Cell Classification Based on Whole-Slide Images with a Deeply Aggregated Neural Network - Qiang Zhai; Bing Fan; Bing Zhang; Jing-Hui Li; Ji-Zhong Liu (Journal of Medical and Biological Engineering, 2022)

Numerical Simulation of the Combined Slope Protection Effect of Living Stump and Bamboo Anchor - Yingbo Zhu; Hui Yang; Yong Liu; Xueliang Jiang; Riwen Deng; Li Huang; Peng Yin; Guojie Lai (Geotechnical and Geological Engineering, 2022)

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss) - Hui-Xia Yu; Yang Li; Wei-Jia Song; Hui Wang; Hao-Lin Mo; Qiao Liu; Xin-Miao Zhang; Ze-Bin Jiang; Li-Xin Wang (Fish Physiology and Biochemistry, 2022)

The neonatal PROC gene rs1799809 polymorphism modifies the association between prenatal air pollutants exposure and PROC promoter methylation - Zhiyuan Li; Meng Yang; Leizhen Duan; Yongxiang Gong; Hongxia Xia; Francis-Kojo Afrim; Hui Huang; Xiaoxue Liu; Fangfang Yu; Yawei Zhang; Yue Ba; Guoyu Zhou (Environmental Science and Pollution Research, 2022)

Sex-specific mediation of placental inflammatory biomarkers in the effects of prenatal phthalate coexposure on preschooler cognitive development - Hui Gao; Juan Tong; Bei-bei Zhu; Meng-long Geng; Hong Gan; Li Sun; Xiao-yan Wu; Kun Huang; Hui Cao; Wen-wen Liu; Shu-man Tao; Peng Ding; et al. (Environmental Science and Pollution Research, 2022)

East Asian summer monsoon changes in subtropical China since late Pleistocene: Evidence from the Ailuropoda-Stegodon fauna - Zhi-wen Li; Li Sun; Bao-sheng Li; Feng-nian Wang; Ding-ding Du; You-gui Song; Hui-Juan Zhang; Liu-qin Chen; Dan Xu (Journal of Mountain Science, 2022)

miR-181b-5p Promotes the Progression of Cholangiocarcinoma by Targeting PARK2 via PTEN/PI3K/AKT Signaling Pathway - Zhe-Long Jiang; Fu-Xing Zhang; Hong-Liang Zhan; He-Jun Yang; Si-Yu Zhang; Zhao-Hui Liu; Yi Jiang; Li-Zhi Lv; Rui-Sheng Ke (Biochemical Genetics, 2022)

Decreased incidence of acute hemorrhagic conjunctivitis associated with enhanced public health intervention during the COVID-19 epidemic in China, 2020 - Li Zhang; Xiangyu Guo; Hui Jiang; Na Zhao; Wei Cheng; Wangli Xu; Shelan Liu (Archives of Virology, 2022)

Comparative transcriptome analysis in three sorghum ( Sorghum bicolor ) cultivars reveal genomic basis of differential seed quality - Wei Zhou; Yaxing Zhou; Zhenguo Wang; Yan Li; Hui Liu; Fengjuan Cui; Shoujun Xu; Zhensheng Shi (Plant Biosystems, 2022)

SYL3-k increases style length and yield of F1 seeds via enhancement of endogenous GA4 content in Oryza sativa L. pistils - Xiaojing Dang; Yuanqing Zhang; Yulong Li; Siqi Chen; Erbao Liu; Bingjie Fang; Qiangming Liu; Dong She; Zhiyao Dong; Zhilan Fan; Dalu Li; Hui Wang; et al. (Theoretical and Applied Genetics, 2022)
Key message SYL3-k allele increases the outcrossing rate of male sterile line and the yield of hybrid F 1 seeds via enhancement of endogenous GA 4 content in Oryza sativa L. pistils. The change in style length might be an adaptation of rice cultivation from south to north in the northern hemisphere. Abstract The style length (SYL) in rice is one of the major factors influencing the stigma exertion, which affects the outcross rate of male sterile line and the yield of hybrid F 1 seeds. However, the biological mechanisms underlying SYL elongation remain elusive. Here, we report a map-based cloning and characterisation of the allele qSYL3-k . The qSYL3-k allele encodes a MADS-box family transcription factor, and it is expressed in various rice organs. The qSYL3-k allele increases SYL via the elongation of cell length in the style, which is associated with a higher GA 4 content in the pistil. The expression level of OsGA3ox2 in pistils with qSYL3-k alleles is significantly higher than that in pistils with qSYL3-n allele on the same genome background of Nipponbare. The yield of F 1 seeds harvested from plants with 7001S SYL3−k alleles was 16% higher than that from plants with 7001S SYL3−n allele. The sequence data at the qSYL3 locus in 136 accessions showed that alleles containing the haplotypes qSYL3 AA , qSYL3 AG , and qSYL3 GA increased SYL, whereas those containing the haplotype qSYL3 GG decreased it. The frequency of the haplotype qSYL3 GG increases gradually from the south to north in the northern hemisphere. These findings will facilitate improvement in SYL and yield of F 1 seeds henceforward.

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma - Cheng Wang; Mingtao Huang; Congcong Chen; Yuancheng Li; Na Qin; Zijian Ma; Jingyi Fan; Linnan Gong; Hui Zeng; Liu Yang; Xianfeng Xu; Jun Zhou; et al. (Science China Life Sciences, 2022)

AgMYB12, a novel R2R3-MYB transcription factor, regulates apigenin biosynthesis by interacting with the AgFNS gene in celery - Hao Wang; Jie-Xia Liu; Kai Feng; Tong Li; Ao-Qi Duan; Yan-Hua Liu; Hui Liu; Ai-Sheng Xiong (Plant Cell Reports, 2022)

β-Catenin Deletion in Regional Neural Progenitors Leads to Congenital Hydrocephalus in Mice - Lin Ma; Yanhua Du; Xiangjie Xu; Hexi Feng; Yi Hui; Nan Li; Guanyu Jiang; Xiaoqing Zhang; Xiaocui Li; Ling Liu (Neuroscience Bulletin, 2022)

QTL mapping and candidate gene mining of flag leaf size traits in Japonica rice based on linkage mapping and genome-wide association study - Jiangxu Wang; Tao Wang; Qi Wang; Xiaodong Tang; Yang Ren; Haiyan Zheng; Kai Liu; Luomiao Yang; Hui Jiang; Yidan Li; Qi Liu; Detang Zou; et al. (Molecular Biology Reports, 2022)

Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury - Yicong Liu; Hui Li; Jiangqi Hu; Zhou Wu; Jie Meng; Yoshinori Hayashi; Hiroshi Nakanishi; Hong Qing; Junjun Ni (Molecular Neurobiology, 2022)

Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling - Qingxiu Yao; Hui Wang; Hengchao Chen; Zhuangzhuang Li; Yumeng Jiang; Zhipeng Li; Jiping Wang; Yazhi Xing; Feng Liu; Dongzhen Yu; Shankai Yin (Molecular Neurobiology, 2022)
Hearing loss is the most common human sensory deficit. Hearing relies on stereocilia, inserted into the cuticular plate of hair cells (HCs), where they play an important role in the perception of sound and its transmission. Although numerous genes have been associated with hearing loss, the function of many hair cell genes has yet to be elucidated. Herein, we focused on nonerythroid spectrin αII (SPTAN1), abundant in the cuticular plate, surrounding the rootlets of stereocilia and along the plasma membrane. Interestingly, mice with HC-specific Sptan1 knockout exhibited rapid deafness, abnormal formation of stereocilia and cuticular plates, and loss of HCs from middle and apical turns of the cochlea during early postnatal stages. Additionally, Sptan1 deficiency led to the decreased spreading of House Ear Institute-Organ of Corti 1 cells, and induced abnormal formation of focal adhesions and integrin signaling in mouse HCs. Altogether, our findings highlight SPTAN1 as a critical molecule for HC stereocilia morphology and auditory function via regulation of focal adhesion signaling.

Retraction Note to: Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes - Michael Nothnagel; Guangyao Fan; Fei Guo; Yongfeng He; Yiping Hou; Shengping Hu; Jiang Huang; Xianhua Jiang; Wook Kim; Kicheol Kim; Chengtao Li; Hui Li; et al. (Human Genetics, 2022)

Regulatory role of miR-129 and miR-384-5p on apoptosis induced by oxygen and glucose deprivation in PC12 cell - Hui-Lin Guan; Yue Guan; Wen-Yuan Li; Jia-Wei Liu; Yu-Jia Zheng; Yan-Zhong Guan; Hong-Feng Liu; Li-Xin Guan; Feng-Guo Zhai (Experimental Brain Research, 2022)

Deinococcus aestuarii sp. nov. and Deinococcus aquaedulcis sp. nov., two novel resistant bacteria isolated from pearl river estuary - Ling-Zi Yin; Jia-Ling Li; Ze-Tao Liu; Bao-Zhu Fang; Pandeng Wang; Xiao-Qing Luo; Lei Dong; Li Duan; Shan-Hui Li; Wen-Jun Li (Antonie van Leeuwenhoek, 2022)

Kangiella shandongensis sp. nov., a novel species isolated from saltern in Yantai, China - Li-Yang Peng; Rui Yin; Shu-Kun Gao; Hui-Ning Jiang; Xiao-Xiao Liu; Yu Ma; Yan-Xia Zhou (Antonie van Leeuwenhoek, 2022)

Not out of the woods yet: Signatures of the prolonged negative genetic consequences of a population bottleneck in a rapidly re‐expanding wader, the black‐faced spoonbill Platalea minor - Shou‐Hsien Li; Yang Liu; Chia‐Fen Yeh; Yuchen Fu; Carol K. L. Yeung; Chun‐Cheng Lee; Chi‐Cheng Chiu; Tung Hui Kuo; Fang‐Tse Chan; Yu‐Chia Chen; Wen‐Ya Ko; Cheng‐Te Yao (Molecular Ecology, 2022)
The long‐term persistence of a population which has suffered a bottleneck partly depends on how historical demographic dynamics impacted its genetic diversity and the accumulation of deleterious mutations. Here we provide genomic evidence for the genetic effect of a recent population bottleneck in the endangered black‐faced spoonbill ( Platalea minor ) after its rapid population recovery. Our data suggest that the bird's effective population size, N e , had been relatively stable (7500–9000) since 22,000 years ago; however, a recent brief yet severe bottleneck ( N e = 20) which we here estimated to occur around the 1940s wiped out >99% of its historical N e in roughly three generations. Despite a >15‐fold population recovery since 1988, we found that black‐faced spoonbill population has higher levels of inbreeding (7.4 times more runs of homozygosity) than its sister species, the royal spoonbill ( P. regia ), which is not thought to have undergone a marked population contraction. Although the two spoonbills have similar levels of genome‐wide genetic diversity, our results suggest that selection on more genes was relaxed in the black‐faced spoonbill; moreover individual black‐faced spoonbills carry more putatively deleterious mutations (Grantham's score > 50), and may therefore express more deleterious phenotypic effects than royal spoonbills. Here we demonstrate the value of using genomic indices to monitor levels of genetic erosion, inbreeding and mutation load in species with conservation concerns. To mitigate the prolonged negative genetic effect of a population bottleneck, we recommend that all possible measures should be employed to maintain population growth of a threatened species.

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

The xyloglucan galactosylation modulates the cell wall stability of pollen tube - Qiqi Wei; Ying Yang; Hui Li; Zhiwen Liu; Rong Fu; Hanqian Feng; Chao Li (Planta, 2021)

Variations in soil properties rather than functional gene abundances dominate soil phosphorus dynamics under short-term nitrogen input - Bing Han; Jingjing Li; Kesi Liu; Hui Zhang; Xiaoting Wei; Xinqing Shao (Plant and Soil, 2021)

Detoxification difference of cadmium between the application of selenate and selenite in native cadmium-contaminated soil - Mingxing Qi; Yang Liu; Yanan Li; Min Wang; Nana Liu; Pornpimol Kleawsampanjai; Fei Zhou; Hui Zhai; Mengke Wang; Quang Toan Dinh; Rui Ren; Dongli Liang (Environmental Science and Pollution Research, 2021)

Driving forces for recovery of forest vegetation after harvesting a subalpine oak forest in eastern Tibetan Plateau - Qinli Xiong; Lingjuan Li; Xiaojin Luo; Xingjin He; Lin Zhang; Kaiwen Pan; Chenggang Liu; Hui Sun (Environmental Science and Pollution Research, 2021)

Dinoflagellate-targeted PCR reveals highly abundant and diverse communities of parasitic dinoflagellates in and near Zhubi Reef, South China Sea - Dajun Qiu; Liangmin Huang; Yunyun Zhuang; Yu Zhong; Yuehui Tan; Xiubao Li; Sheng Liu; Hui Huang; Senjie Lin (Coral Reefs, 2021)

Australian propolis ethanol extract exerts antibacterial activity against methicillin-resistant Staphylococcus aureus by mechanisms of disrupting cell structure, reversing resistance, and resisting biofilm - Fei Wang; Hui Liu; Junya Li; Wenwen Zhang; Bin Jiang; Hongzhuan Xuan (Brazilian Journal of Microbiology, 2021)

Application of lipidomics strategy to explore aging-related biomarkers and potential anti-aging mechanisms of ginseng - Shenshen Yang; Yaqian Dong; Yuechen Liu; Xingxu Yan; Guijiang Sun; Guoxiang Jia; Xiaokai Li; Hui Liu; Haihua Su; Yubo Li (Biogerontology, 2021)

Evaluation of four artificial diets on demography parameters of Neoseiulus barkeri - Ya-Ying Li; Jin-Ge Yuan; Ming-Xiu Liu; Zi-Hui Zhang; Hai-Wei Zhou; Huai Liu (BioControl, 2021)

Enhanced expression of DNA methyltransferase 1-associated protein1 gene thermotolerance in a high-temperature acclimated predatory mite Neoseiulus barkeri - Ya-Ying Li; Chuan-Bei Tian; Yi-Xia Wu; Tian-Di Niu; Hao Wang; Wen-Hui Fan; Huai Liu (BioControl, 2021)

The first third-generation HIV-1 circulating recombinant form (CRF114_0155) identified in central China - Yang Li; Yan Zhang; Hongye Wang; Long Liu; Hui Chen; Shuanhu Zhang; Wenying Wu; Rongge Yang (Archives of Virology, 2021)

Assessment of probiotic adhesion and inhibitory effect on Escherichia coli and Salmonella adhesion - Ya Wang; Dan Jia; Jia-hui Wang; He-hai Li; Jun-long Liu; Ai-hong Liu; Jin-ming Wang; Gui-quan Guan; Jian-xun Luo; Hong Yin; You-quan Li (Archives of Microbiology, 2021)

Correction to: AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis - Yu Liu; Hui Yang; Lina Song; Nan Li; Qiu-Yue Han; Cui Tian; Erhe Gao; Jie Du; Yun-Long Xia; Hui-Hua Li (Apoptosis, 2021)

Controlling pathogenic risks of water treatment biotechnologies at the source by genetic editing means - Jie Wu; Dong‐Feng Liu; Hui‐Hui Li; Di Min; Jia‐Qi Liu; Peng Xu; Wen‐Wei Li; Han‐Qing Yu; Yong‐Guan Zhu (Environmental Microbiology, 2021)
Summary Antimicrobial‐resistant pathogens in the environment and wastewater treatment systems, many of which are also important pollutant degraders and are difficult to control by traditional disinfection approaches, have become an unprecedented treat to ecological security and human health. Here, we propose the adoption of genetic editing techniques as a highly targeted, efficient and simple tool to control the risks of environmental pathogens at the source. An ‘all‐in‐one’ plasmid system was constructed in Aeromonas hydrophila to accurately identify and selectively inactivate multiple key virulence factor genes and antibiotic resistance genes via base editing, enabling significantly suppressed bacterial virulence and resistance without impairing their normal phenotype and pollutant‐degradation functions. Its safe application for bioaugmented treatment of synthetic textile wastewater was also demonstrated. This genetic‐editing technique may offer a promising solution to control the health risks of environmental microorganisms via targeted gene inactivation, thereby facilitating safer application of water treatment biotechnologies.

Late Silurian to early Devonian development of the Chingiz accretion arc, West Junggar: insights into accretion arc evolution in the Central Asia Orogenic Belt - Yichao Chen; Ji’En Zhang; Wenjiao Xiao; Renjie Zhou; Shuaihua Song; Zhiyong Zhang; Songjian Ao; Miao Sang; Qian W.L. Zhang; Rui Li; Zhen M.G. Li; Yin Liu; et al. (International Geology Review, 2021)

Dammarane-type saponins from Gynostemma pentaphyllum and their cytotoxicities - Wei-Ye Cui; Yulian Jin; Hui Liu; Ma-Li Zu; Xin-Fang Zhai; Ce Yang; Yu-Long Gu; Yong Cheng; Xiang-Lan Piao (Natural Product Research, 2021)

Alkaloids with acetylcholinesterase inhibitory activity from Corydalis racemosa (Thunb.) Pers - Hui-Na Yao; Zhi-Tian Peng; Yun-Feng Zhang; Di-Fa Liu; Bing-Feng Huang; Peng-Fei Tu; Yun-Fang Zhao; Hui-Xia Huo; Jun Li (Natural Product Research, 2021)

Abnormal meiosis in fertile and sterile triploid cyprinid fish - Chun Zhang; Qi Li; La Zhu; Wangchao He; Conghui Yang; Hui Zhang; Yu Sun; Luojing Zhou; Yuandong Sun; Shurun Zhu; Chang Wu; Min Tao; et al. (Science China Life Sciences, 2021)

Removal of roosters alters the domestic phenotype and microbial and genetic profile of hens - Hai Xiang; Siyu Chen; Hui Zhang; Xu Zhu; Dan Wang; Huagui Liu; Jikun Wang; Tao Yin; Langqing Liu; Minghua Kong; Jian Zhang; Hua Li; et al. (Science China Life Sciences, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

A new ergostane derivative from the leaves of Heynea trijuga Roxburgh - Shou-Bai Liu; Zheng Cui; Hui-Qin Chen; Hao Wang; Wen-Hua Dong; Cai-Hong Cai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

A review of the botany, traditional uses, phytochemistry and pharmacology of Nepeta tenuifolia Briq. - Mingqiu Shan; Yulan Jiang; Yuanyuan Fu; Yongyi Zhou; Zhihui Lu; Sheng Yu; Hui Yan; Chanchan Liu; Peidong Chen; Beihua Bao; Li Zhang; Qinan Wu (Phytochemistry Reviews, 2021)

Pseudotime Ordering Single-Cell Transcriptomic of β Cells Pancreatic Islets in Health and Type 2 Diabetes - Kaixuan Bao; Zhicheng Cui; Hui Wang; Hui Xiao; Ting Li; Xingxing Kong; Tiemin Liu (Phenomics, 2021)

Influence of sedimentation rate on the environmental capacity of total nitrogen in the water of Bohai Bay, China - Yan Zhang; Anding Li; Ye Tian; Bin Zhou; Man Chai; Hui Li; Qiongqiong Liu; Hui Zeng; Weijie Xu (Journal of Soils and Sediments, 2021)

Ectomycorrhizal symbioses increase soil calcium availability and water use efficiency of Quercus acutissima seedlings under drought stress - Yanan Li; Tengzi Zhang; Yongbin Zhou; Xiaoming Zou; You Yin; Hui Li; Liying Liu; Songzhu Zhang (European Journal of Forest Research, 2021)

Design and Evaluation of Multiplex One-Step Reverse Transcription PCR–Dipstick Chromatography Method for the Analysis of Seven Respiratory Pathogens - Li Luo; Qianming Chen; Sheng Qin; Qiang Luo; Zhenjie Liu; Qiong Li; Shuilan Zheng; Xianzhang Huang; Peifeng Ke; Xiangsheng Yang; Hui Xiao; Ning Xu (Current Microbiology, 2021)

High-K calc-alkaline to shoshonitic intrusions in SE Tibet: implications for metasomatized lithospheric mantle beneath an active continental margin - Ren-Zhi Zhu; Ewa Słaby; Shao-Cong Lai; Li-Hui Chen; Jiangfeng Qin; Chao Zhang; Shaowei Zhao; Fangyi Zhang; Wen-hang Liu; Mike Fowler (Contributions to Mineralogy and Petrology, 2021)

Resting-state abnormalities in functional connectivity of the default mode network in autism spectrum disorder: a meta-analysis - Qing Wang; Hua-Yun Li; Yun-Da Li; Ya-Ting Lv; Hui-Bin Ma; An-Feng Xiang; Xi-Ze Jia; Dong-Qiang Liu (Brain Imaging and Behavior, 2021)

An Investigation of Toxic Metal Levels (Pb, Cd, Cr, As, Hg) in Dried Porphyra and Laminaria Collected from Coastal Cities, China - Yan Chen; Yong-tao Liu; Fu-hua Wang; Dian Wen; Hui Yang; Xiao-li Zhao (Biological Trace Element Research, 2021)

Genome-Wide Analysis of the Thioredoxin Gene Family in Gossypium hirsutum L. and the Role of the Atypical Thioredoxin Gene GhTRXL3-2 in Flowering - Hui Liu; Yunfei Li; Xianzhong Huang (Journal of Plant Biology, 2021)
Thioredoxin (TRX) is a highly conserved low-molecular-weight protein and a ubiquitous antioxidant enzyme that plays key role in the regulation of plant growth and development. Here, using the whole-genome sequence, we performed a systematic analysis for the TRX gene family in upland cotton ( Gossypium hirsutum L.) and analyzed their structural characteristics, evolution, and expression profiles during growth and development. At least 86 GhTRX members, 40 typical and 46 atypical, were identified in the cotton genome, and they were unevenly distributed on the 26 chromosomes. Conserved domains and phylogenic tree construction classified the typical TRX gene family into seven subfamilies and the atypical TRX into nine subfamilies. An evolutionary analysis revealed that the TRX gene family underwent purification selection during evolution. In addition, an RNA-Seq analysis showed that, during vegetative and reproductive development, the differences in transcript abundance levels and organ-specific expression patterns suggest functional diversity. Biochemical assays demonstrated that the atypical TRX protein GhTRXL3-2 interacted with the cotton FLOWERING LOCUS T protein GhFT. The overexpression of GhTRXL3-2 in Arabidopsis thaliana resulted in early flowering compared with control plants. Additionally, the silencing of GhTRXL3-2 in cotton delayed maturation, suggesting that it has important roles in cotton’s flowering regulation. These results help clarify the evolution of the TRX genes and elucidate their biological functions in cotton flowering regulation.

Whole-exome sequencing identified a novel mutation in CHM of a Chinese family - Hui Tang; Jun Mao; Jingjing Xiang; Minjuan Liu; Haibo Li; Ting Wang (Journal of Genetics, 2021)

Experimental study on integrated and autonomous conductivity-temperature-depth (CTD) sensor applied for underwater glider - Bin Lv; Hai-lin Liu; Yi-fan Hu; Cheng-xuan Wu; Jie Liu; Hai-jing He; Jie Chen; Jian Yuan; Zhao-wen Zhang; Lin Cao; Hui Li (Marine Georesources & Geotechnology, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

Transcriptome Sequencing of a Novel Albino Mutant of Hexaploid Sweetpotato - Mohamed Hamed Arisha; Yan Hui; Muhammad Qadir Ahmad; Tang Wei; Kou Meng; Liu Yaju; Wang Xin; Zhang Yungang; Li Qiang (Plant Molecular Biology Reporter, 2021)

Experimental investigation on synergetic prediction of rockburst using the dominant-frequency entropy of acoustic emission - Chunlai Wang; Cong Cao; Yubo Liu; Changfeng Li; Guangyong Li; Hui Lu (Natural Hazards, 2021)

Developing a two-step improved damage creep constitutive model based on soft rock saturation-loss cycle triaxial creep test - Anrun Li; Hui Deng; Haojie Zhang; Mingliang Jiang; Hanhan Liu; Yuyue Xiao; Jing Wen (Natural Hazards, 2021)

Spatio-temporal characteristics and control strategies in the early period of COVID-19 spread: a case study of the mainland China - Jiachen Ning; Yuhan Chu; Xixi Liu; Daojun Zhang; Jinting Zhang; Wangjun Li; Hui Zhang (Environmental Science and Pollution Research, 2021)

Combined use of lime, bentonite, and biochar for immobilization of Cd and mobilization of Se in paddy soil - Zhiqiang Xu; Bin Liang; Zhonghui Li; Hui Jiang; Ting Liu; Qiubo Wang; Jiaxin Duan (Environmental Science and Pollution Research, 2021)

An experimental study on cutting tool hardness optimization for shield TBMs during dense fine silty sand ground tunneling - Xiao-Ping Zhang; Shao-Hui Tang; Quan-Sheng Liu; Xin-Bin Tu; Peng Chen; Fang-Yi Li (Bulletin of Engineering Geology and the Environment, 2021)

Metabolic pathway analysis of walnut endophytic bacterium Bacillus subtilis HB1310 related to lipid production from fermentation of cotton stalk hydrolysate based on genome sequencing - Qin Zhang; Panpan Liu; Yanbin Li; Hui Jiang (Biotechnology Letters, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

Alpha-Lipoic Acid Attenuates Cadmium- and Lead-Induced Neurotoxicity by Inhibiting Both Endoplasmic-Reticulum Stress and Activation of Fas/FasL and Mitochondrial Apoptotic Pathways in Rat Cerebral Cortex - Yan Yuan; Shi Wen Zhao; Shuang Quan Wen; Qiao Ping Zhu; Li Wang; Hui Zou; Jian Hong Gu; Xue Zhong Liu; Jian Chun Bian; Zong Ping Liu (Neurotoxicity Research, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Higher photochemical production of bromophenol by quinone-like substances extracted from humic substances using a new emodin-imprinted polymer - Hui Liu; Xiaojun Qiu; Zhi Li; Xiaomei Zhu; Bing Sun; Xiaoxing Zhang (Environmental Chemistry Letters, 2021)

Flexible reconfiguration of functional brain networks as a potential neural mechanism of creativity - Junchao Li; Natasza Orlov; Zengjian Wang; Bingqing Jiao; Yibo Wang; Huawei Xu; Hui Yang; Yingying Huang; Yan Sun; Peng Zhang; Rengui Yu; Ming Liu; et al. (Brain Imaging and Behavior, 2021)

Heterogeneity of tight sandstone reservoirs based on fractal theory: the Xu-6 member of Xujiahe Formation in Guang'an area, central Sichuan Basin - Fang Shen; Liang Yue; Ziliang Liu; Wei Yang; Kaarel Mänd; Hui Jin; Fengjie Li; Yue Zhou; Minghe Zhang; Rui Jiang (Arabian Journal of Geosciences, 2021)

Disturbance-Mediated Changes in Coral Reef Habitat Provoke a Positive Feeding Response in a Major Coral Reef Detritivore, Ctenochaetus striatus - Xianzhi Lin; Simin Hu; Yong Liu; Li Zhang; Hui Huang; Sheng Liu (Frontiers in Marine Science, 2021)
Coral reefs are undergoing global phase shifts from coral-dominated to algae-dominated stages. The negative effects of this substratum shift on the diversity and abundance of fish have been well documented, but the influence on fish feeding is less studied, which may limit a deeper understanding of trophic pathways in such a disturbed system. In this study, we investigated the feeding response of a numerically dominant fish species Ctenochaetus striatus to different substrate types, including hard coral, short algal turfs (SATs, <5 mm), and long algal turfs (LATs, >5 mm), on reefs in the South China Sea. The biomass of C. striatus showed an inverted U-shaped relationship with coral coverage and a significant positive correlation with SAT coverage ( p < 0.05), indicating that rising SAT coverage associated with moderate coral loss provoked a feeding response in C. striatus . Stomach contents of C. striatus , analyzed using high-throughput sequencing (HTS), were dominated by algal sequences (relative read abundance, RRA > 80.0%), including macroalgae, filamentous algae, and microalgae (e.g., Symbiodinium and Prorocentrum ). The sequence number and diversity of microalgae (mainly dinoflagellates) tended to be abundant (RRA 13.5–36.5%) with increased SAT cover, but brown algae sequences (RRA 17.2–57.8%) or green algae sequences (RRA > 50.7% except one site) dominated the stomach content DNA in reefs with high coral cover and high LAT or macroalgal cover, respectively. Considering the limited ability of C. striatus to remove mature algae, macroalgal DNA might be from algal debris. Our results indicate that C. striatus populations respond positively to conditions of moderate coral loss through increases in body condition identified as increased biomass. These responses are correlated to the expansion of SAT’s as coral cover declined, however, this relationship reverses if coral loss is high due to the succession of LAT’s over SAT’s and a corresponding decrease in the quality of food available. Our use of HTS has nevertheless identified the importance of detritivory in the flow of energy through reefs in the Anthropocene which are increasingly becoming depauperate in hard coral.

Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway - Zhiheng Zhang; Wenhan Liu; Meilun Shen; Xiangying Ma; Rouqian Li; Xiaodi Jin; Hui Bai; Li Gao (Molecular Neurobiology, 2021)

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

The effect of land use change and soil redistribution on soil organic carbon dynamics in karst graben basin of China - Gaoyong Lan; Chun Liu; Hua Wang; Wei Tang; Xia Wu; Hui Yang; Linling Tu; Bill X. Hu; Jianhua Cao; Qiang Li (Journal of Soils and Sediments, 2021)

Cysteiniphilum marinum sp. nov., isolated from coastal seawater - Hai-Min Luo; Jun-Hui Feng; Liang-Hui Li; Meng-Meng Li; Ru-Qin Liu; Fu Chen; Ying Lin; Wen-Jun Li; Ping-Hua Qu; Min Xiao (Antonie van Leeuwenhoek, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

Lipocalin-2-induced proliferative endoplasmic reticulum stress participates in Kawasaki disease-related pulmonary arterial abnormalities - Zhaoling Shi; Yue Yin; Chen Li; Hui Ding; Nan Mu; Yishi Wang; Shanshan Jin; Heng Ma; Manling Liu; Jie Zhou (Science China Life Sciences, 2021)

Association of Single Nucleotide Polymorphism at rs2275294 in the ZNF512B Gene with Prognosis in Amyotrophic Lateral Sclerosis - Haixia Jiang; Baiyuan Yang; Fang Wang; Kelu Li; Yongyun Zhu; Bin Liu; Hui Ren; Sijia Tian; Yanming Xu; Ailan Pang; Xinglong Yang (NeuroMolecular Medicine, 2021)

Seismic signal characteristics and interpretation of the 2020 “6.17” Danba landslide dam failure hazard chain process - Yan Yan; Yifei Cui; Dingzhu Liu; Hui Tang; Yongjian Li; Xin Tian; Lei Zhang; Sheng Hu (Landslides, 2021)

Sublethal dose of warfarin induction promotes the accumulation of warfarin resistance in susceptible Norway rats - Xiaohui Ma; Yan Chen; Yaqi Ying; Yuanzhao Geng; Dawei Wang; Ning Li; Xiao-Hui Liu; Ying Song (Journal of Pest Science, 2021)

L-3-n-Butylphthalide Effectively Improves the Glymphatic Clearance and Reduce Amyloid-β Deposition in Alzheimer’s Transgenic Mice - Bo Zhang; Wei Li; Youguang Zhuo; Hui Xiang; Wenfeng Li; Hongying Liu; Longchang Xie; Qingchun Gao; Sheng Tan (Journal of Molecular Neuroscience, 2021)

Using water-based drilling cuttings from shale gas development to manufacture sintered bricks: a case study in the southern Sichuan Basin, China - Wenshi Liu; Hui Yuan; Zhenzhen Fan; Jing Li; Lingru Sun (Environmental Science and Pollution Research, 2021)

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

Spatial distribution pattern in mammal and bird richness and their relationship with ecosystem services in Sanjiangyuan National Park, China - Hua-wei Wan; Hao-xin Li; Jin-hui Wu; Yu-ping Liu (Journal of Mountain Science, 2021)

Synergistic Effect of Moderate Steam Explosion Pretreatment and Bovine Serum Albumin Addition for Enhancing Enzymatic Hydrolysis of Poplar - Xiaodi Wang; Dayong Ding; Zhong Liu; Jinru Cheng; Xin Li; Lanfeng Hui (BioEnergy Research, 2021)

Molecular surveillance of coxsackievirus A16 in southern China, 2008–2019 - Lina Yi; Hanri Zeng; Huanying Zheng; Jinju Peng; Xue Guo; Leng Liu; Qianling Xiong; Limei Sun; Xiaohua Tan; Jianfeng He; Jing Lu; Hui Li (Archives of Virology, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Natural abundance of 13 C and 15 N provides evidence for plant–soil carbon and nitrogen dynamics in a N‐fertilized meadow - Ruzhen Wang; Josep Peñuelas; Tian Li; Heyong Liu; Hui Wu; Yuge Zhang; Jordi Sardans; Yong Jiang (Ecology, 2021)
Natural abundance of carbon (C) and nitrogen (N) stable isotope ratios (δ 13 C and δ 15 N) has been used to indicate ecosystem C and N status and cycling; however, use of this approach to infer plant and microbial N preference under projected ecosystem N enrichment is limited. Here, we investigated natural abundance δ 13 C and δ 15 N of five dominant plant species, and soil δ 15 N of microbial biomass and available N forms under N addition in a meadow steppe. Additional N, applied as urea, led to decreases in δ 15 N of soil NO 3 − (δ 15 N nitrate , from 3.0 to 0.4‰) and increases in δ 15 N of soil (δ 15 N ammonium , from −1.3 to 11‰) and dissolved organic N (δ 15 N DON , from 8.5 to 15‰) that reflected increased net nitrification rates, a possible increase in NH 3 volatilization, and greater availability of the three N forms. An overall increase in δ 15 N of soil total N (δ 15 N TN ) from 7.1 to 7.9‰ indicated accelerated and greater openness of soil N cycling that was also partially revealed by enhanced net N mineralization rates. Plant δ 15 N, which ranged from −1.8 to 2.1‰, generally decreased with N addition, indicating a greater reliance on soil NO 3 − under N‐enrichment conditions. Nitrogen addition decreased δ 15 N of microbial biomass N (from 14 to 2.8‰), possibly because of a shift in preferential N form (DON to ), that indicated a convergence of plant and microbial preferential N forms and an increase in plant–microbial N competition. Microbes were thus more flexible than plants in the use of different forms of N. Addition of N decreased plant litter δ 13 C, whereas plant species δ 13 C remained unaffected, likely because of a shift in the abundance of dominant species with a greater proportion of biomass coming from δ 13 C‐depleted species. Enrichment factor (the difference in plant δ 15 N relative to δ 15 N TN ) of four nonlegume species was negatively related to soil inorganic N availability, net nitrification rate, and net N mineralization rate, and was proven to be a good indicator of ecosystem N status. Our study highlights the importance of natural abundance of 15 N as an indicator of plant–microbial N competition and ecosystem N cycling in meadow steppe grasslands under projected ecosystem N enrichment.

Underwater Image Restoration via Non-Convex Non-Smooth Variation and Thermal Exchange Optimization - Qingliang Jiao; Ming Liu; Pengyu Li; Liquan Dong; Mei Hui; Lingqin Kong; Yuejin Zhao (Journal of Marine Science and Engineering, 2021)
The quality of underwater images is an important problem for resource detection. However, the light scattering and plankton in water can impact the quality of underwater images. In this paper, a novel underwater image restoration based on non-convex, non-smooth variation and thermal exchange optimization is proposed. Firstly, the underwater dark channel prior is used to estimate the rough transmission map. Secondly, the rough transmission map is refined by the proposed adaptive non-convex non-smooth variation. Then, Thermal Exchange Optimization is applied to compensate for the red channel of underwater images. Finally, the restored image can be estimated via the image formation model. The results show that the proposed algorithm can output high-quality images, according to qualitative and quantitative analysis.

Effects of prenatal exposure to bisphenols on newborn leucocyte telomere length: a prospective birth cohort study in China - Jun Liang; Yantao Shao; Dongping Huang; Chunxiu Yang; Tao Liu; Xiaoyun Zeng; Chunling Li; Zhenghua Tang; Jennifer Tan Hui Juan; Yanye Song; Shun Liu; Xiaoqiang Qiu (Environmental Science and Pollution Research, 2021)

Transcriptomic and metabolomic profiling reveals the protective role of anthocyanins in alleviating low phosphate stress in maize - Laming Pei; Jiajia Liu; Yuanyuan Zhou; Yuhang Jiang; Hui Li (Physiology and Molecular Biology of Plants, 2021)

Taste Masking Study Based on an Electronic Tongue: the Formulation Design of 3D Printed Levetiracetam Instant-Dissolving Tablets - Zengming Wang; Jingru Li; Xiaoxuan Hong; Xiaolu Han; Boshi Liu; Xianfu Li; Hui Zhang; Jing Gao; Nan Liu; Xiang Gao; Aiping Zheng (Pharmaceutical Research, 2021)
Purpose Proper taste-masking formulation design is a critical issue for instant-dissolving tablets (IDTs). The purpose of this study is to use the electronic tongue to design the additives of the 3D printed IDTs to improve palatability. Methods A binder jet 3D printer was used to prepare IDTs of levetiracetam. A texture analyzer and dissolution apparatus were used to predict the oral dispersion time and in vitro drug release of IDTs, respectively. The palatability of different formulations was investigated using the ASTREE electronic tongue in combination with the design of experiment and a model for masking bitter taste. Human gustatory sensation tests were conducted to further evaluate the credibility of the results. Results The 3D printed tablets exhibited rapid dispersion (<30 s) and drug release (2.5 min > 90%). The electronic tongue had an excellent ability of taste discrimination, and levetiracetam had a good linear sensing performance based on a partial least square regression analysis. The principal component analysis was used to analyze the signal intensities of different formulations and showed that 2% sucralose and 0.5% spearmint flavoring masked the bitterness well and resembled the taste of corresponding placebo. The results of human gustatory sensation test were consistent with the trend of the electronic tongue evaluation. Conclusions Owing to its objectivity and reproducibility, this technique is suitable for the design and evaluation of palatability in 3D printed IDT development.

Spatial prediction of soil calcium carbonate content based on Bayesian maximum entropy using environmental variables - Mei Shan; Shuang Liang; Hongchen Fu; Xiaoli Li; Yu Teng; Jingwen Zhao; Yaxin Liu; Chen Cui; Li Chen; Hai Yu; Shunbang Yu; Yanling Sun; et al. (Nutrient Cycling in Agroecosystems, 2021)

Design, synthesis and evaluation of dihydrotriazine derivatives-bearing 5-aryloxypyrazole moieties as antibacterial agents - Tian-Yi Zhang; Chun-Shi Li; Ming-Yue Cui; Xue-Qian Bai; Jiang-Hui Chen; Ze-Wen Song; Bo Feng; Xue-Kun Liu (Molecular Diversity, 2021)

Flavonoids improve drought tolerance of maize seedlings by regulating the homeostasis of reactive oxygen species - Baozhu Li; Ruonan Fan; Guiling Sun; Ting Sun; Yanting Fan; Shenglong Bai; Siyi Guo; Shiquan Huang; Jiong Liu; Hui Zhang; Pengtao Wang; Xiaohong Zhu; et al. (Plant and Soil, 2021)
Background and aims As drought threatens the yield and quality of maize ( Zea mays L.), it is important to dissect the molecular basis of maize drought tolerance. Flavonoids, participate in the scavenging of oxygen free radicals and alleviate stress-induced oxidative damages. This study aims to dissect the function of flavonoids in the improvement of maize drought tolerance. Methods Using far-infrared imaging screening, we previously isolated a drought overly insensitivity ( doi ) mutant from an ethyl methanesulfonate (EMS)-mutagenized maize library and designated it as doi57 . In this study, we performed a physiological characterization and transcriptome profiling of doi57 in comparison to corresponding wild-type B73 under drought stress. Results Under drought stress, doi57 seedlings displayed lower leaf-surface temperature (LST), faster water loss, and better performance in growth than B73. Transcriptome analysis reveals that key genes involved in flavonoid biosynthesis are enriched among differentially expressed genes in doi57 . In line with these results, more flavonols and less hydrogen peroxide (H 2 O 2 ) were accumulated in guard cells of doi57 than in those of B73 with the decrease of soil water content (SWC). Moreover, the capacity determined from doi57 seedling extracts to scavenge oxygen free radicals was more effective than that of B73 under the drought treatment. Additionally, doi57 seedlings had higher photosynthetic rates, stomatal conductance, transpiration rates, and water use efficiency than B73 exposed to drought stress, resulting in high biomass and greater root/shoot ratios in doi57 mutant plants. Conclusion Flavonoids may facilitate maize seedling drought tolerance by lowering drought-induced oxidative damage as well regulating stomatal movement.

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

COVID-19 illness and autoimmune diseases: recent insights - Juan Li; Hong-Hui Liu; Xiao-Dong Yin; Cheng-Cheng Li; Jing Wang (Inflammation Research, 2021)

Comprehensive dynamic analysis of proteins in the spermatheca of female Haemaphysalis longicornis after copulation - Xiaoshuang Wang; Yuhong Hu; Yanan Han; Xiaomin Xue; Mengxue Li; Xiaohong Yang; Siyang Zhou; Hui Wang; Jingze Liu (Experimental and Applied Acarology, 2021)

Clinical and microbiological characteristics of adults with hospital-acquired pneumonia: a 10-year prospective observational study in China - Yuyao Yin; Chunjiang Zhao; Henan Li; Longyang Jin; Qi Wang; Ruobing Wang; Yawei Zhang; Jiangang Zhang; Hui Wang; Chunxia Yang; Bin Cao; Yingmei Liu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Morphology and composition of particles emitted from conventional and alternative fuel vehicles - Zhenzhen Lu; Shunxi Deng; Xi Liu; Lihui Huang; Ruixu Zhang; Hui Song; Guanghua Li (Environmental Science and Pollution Research, 2021)

Increased depression risk for elderly women with high blood levels of strontium and barium - Jia Lv; Yan-ling Li; Wen-qiang Ren; Rong Li; Jian-rong Chen; Chao Bao; Zhi-ping Du; Shun Feng; Ling Gu; Hui Gao; Kai-yong Liu; Lin-sheng Yang; et al. (Environmental Chemistry Letters, 2021)

miR-23b Attenuates LPS-Induced Inflammatory Responses in Acute Lung Injury via Inhibition of HDAC2 - Zhi-Feng Luo; Xiang-Hui Jiang; Huan Liu; Li-Yuan He; Xiong Luo; Fu-Chun Chen; Yu-Lin Tan (Biochemical Genetics, 2021)

Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71 - Ya-Ping Li; Mu-Qi Wang; Chen-Rui Liu; Hui-Ling Deng; Yuan Wu; Shuang-Suo Dang; Li-Hong Xu (Archives of Virology, 2021)

Spatial environment design and comfort simulation of high-latitude building bottom based on geological conditions - Hui Liu; Nan Zhang; Ning Li; Ping Zhang; Xiujuan Jiang (Arabian Journal of Geosciences, 2021)

New cytotoxic biflavones from Selaginella doederleinii - Li-Fei Liu; Hui-Hui Sun; Jian-Bing Tan; Qi Huang; Fei Cheng; Kang-Ping Xu; Zhen-Xing Zou; Gui-Shan Tan (Natural Product Research, 2021)

DBSCAN-based point cloud extraction for Tomographic synthetic aperture radar (TomoSAR) three-dimensional (3D) building reconstruction - Ziye Guo; Hui Liu; Lei Pang; Li Fang; Wenna Dou (International Journal of Remote Sensing, 2021)

Essential oil from Artemisia annua aerial parts: composition and repellent activity against two storage pests - Hong Liu; Shan-Shan Guo; Li Lu; Dian Li; Jun Liang; Zhong-Hui Huang; Yan-Mei Zhou; Wen-Juan Zhang; Shushan Du (Natural Product Research, 2021)

Genome-Wide Analysis of the WRKY Transcription Factor Gene Family and Their Response to Salt Stress in Rubber Tree - Hong Nan; Yang-Lei Lin; Jin Liu; Hui Huang; Wei Li; Li-zhi Gao (Tropical Plant Biology, 2021)

Peptides YYGGEGSSSEQG and SESEM Inhibit TNF-α-Induced Smooth Muscle Cells Proliferation and Migration Through Their Bindings to TNF-α Receptor - Dong-Hui Geng; Zhiyuan Ju; Tianzhen Xiao; Sumei Zhou; Lu Huang; Liya Liu; Xianrong Zhou; Lili Wang; Li-Tao Tong (International Journal of Peptide Research and Therapeutics, 2021)

High-Level Expression and Purification of Melittin in Escherichia coli Using SUMO Fusion Partner - Qiu-chi Chen; Lei Liu; Tian-Yi Yu; Lu Tang; Mo-li Yin; Wen-he Zhu; Xiu-yun Jiang; Hui-yan Wang (International Journal of Peptide Research and Therapeutics, 2021)

SP1-induced AFAP1-AS1 contributes to proliferation and invasion by regulating miR-497-5p/CELF1 pathway in nasopharyngeal carcinoma - Hui Jin; Gengtian Liang; Liping Yang; Li Liu; Binru Wang; Fengqin Yan (Human Cell, 2021)

Protective effects of dietary betaine on intestinal barrier function and cecal microbial community in indigenous broiler chickens exposed to high temperature environment - Wen-Chao Liu; Yan Guo; Li-Long An; Zhi-Hui Zhao (Environmental Science and Pollution Research, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Reclassification of Algibacter wandonensis as a Later Heterotypic Synonym of Algibacter lectus Based on Whole-Genome Sequence Analysis - Ang Liu; Hui Wang; Yuan-Yuan Yang; Qing-Jie Xue; Xiu-Zhen Li (Current Microbiology, 2021)

Accumulation and Depuration of Cd and its Effect on the Expressions of Metallothionein and Apoptotic Genes in Litopenaeus vannamei - Ling Li; Yu-Chun Shen; Jin-Rong Liang; Hu Liu; Tian-Ci Chen; Hui Guo (Bulletin of Environmental Contamination and Toxicology, 2021)

Production of 1,3-propanediol and lactic acid from crude glycerol by a microbial consortium from intertidal sludge - Li-Li Jiang; Feng-Yi Liu; Wei Yang; Chang-Li Li; Bao-Wei Zhu; Xiu-Hui Zhu (Biotechnology Letters, 2021)

Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease - Meng Zhang; Mengying Wang; Hui Wang; Ying Zhang; Zhengzheng Li; Yiping Feng; Yinan Liu; Yue Liu; Yucheng Liao; Wenjun Wang; Qian Fang; Jinghong Chen (Biological Trace Element Research, 2021)

Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China - Qing-Hai Wang; Xiang-Ying Li; Ting-Ting Xu; Meng-Ai Zhang; Yu-Hui Yang; Pei-Bo Feng; Su-Su Fan; Zhen-Yu Liu (Journal of General Plant Pathology, 2021)

Suppression of miR-4463 promotes phenotypic switching in VSMCs treated with Ox-LDL - Xueqin Wang; Hui Li; Yuetian Zhang; Qi Liu; Xiaolei Sun; Xuemei He; Qian Yang; Ping Yuan; Xiangyu Zhou (Cell and Tissue Research, 2021)

A novel ensemble reinforcement learning gated unit model for daily PM2.5 forecasting - Yanfei Li; Zheyu Liu; Hui Liu (Air Quality, Atmosphere & Health, 2021)

Numerical study of scour depth effect on wave-induced seabed response and liquefaction around a pipeline - Hui Li; Shuqing Wang; Xuguang Chen; Cun Hu; Jinzhong Liu (Marine Georesources & Geotechnology, 2021)

QTL mapping for foxtail millet plant height in multi-environment using an ultra-high density bin map - Qiang He; Hui Zhi; Sha Tang; Lu Xing; Suying Wang; Haigang Wang; Aiying Zhang; Yuhui Li; Ming Gao; Haijin Zhang; Guoqiu Chen; Shutao Dai; et al. (Theoretical and Applied Genetics, 2021)

A candidate PpRPH gene of the D locus controlling fruit acidity in peach - Lu Wang; Xiaohan Jiang; Li Zhao; Furong Wang; Yudi Liu; Hui Zhou; Huaping He; Yuepeng Han (Plant Molecular Biology, 2021)

Seed-specific expression of TaYUC10 significantly increases auxin and protein content in wheat seeds - Yanlin Yang; Na Li; Wenrong Hui; Binjie Yuan; Pan Fan; Jingxia Liu; Honggang Wang; Deshun Feng (Plant Cell Reports, 2021)

Using Composite Phenotypes to Reveal Hidden Physiological Heterogeneity in High-Altitude Acclimatization in a Chinese Han Longitudinal Cohort - Yi Li; Yanyun Ma; Kun Wang; Menghan Zhang; Yi Wang; Xiaoyu Liu; Meng Hao; Xianhong Yin; Meng Liang; Hui Zhang; Xiaofeng Wang; Xingdong Chen; et al. (Phenomics, 2021)
Altitude acclimatization is a human physiological process of adjusting to the decreased oxygen availability. Since several physiological processes are involved and their correlations are complicated, the analyses of single traits are insufficient in revealing the complex mechanism of high-altitude acclimatization. In this study, we examined these physiological responses as the composite phenotypes that are represented by a linear combination of physiological traits. We developed a strategy that combines both spectral clustering and partial least squares path modeling (PLSPM) to define composite phenotypes based on a cohort study of 883 Chinese Han males. In addition, we captured 14 composite phenotypes from 28 physiological traits of high-altitude acclimatization. Using these composite phenotypes, we applied k-means clustering to reveal hidden population physiological heterogeneity in high-altitude acclimatization. Furthermore, we employed multivariate linear regression to systematically model (Models 1 and 2) oxygen saturation (SpO 2 ) changes in high-altitude acclimatization and evaluated model fitness performance. Composite phenotypes based on Model 2 fit better than single trait-based Model 1 in all measurement indices. This new strategy of using composite phenotypes may be potentially employed as a general strategy for complex traits research such as genetic loci discovery and analyses of phenomics.

Curcumin protects thymus against D-galactose-induced senescence in mice - Jie-han Li; Ting-ting Wei; Li Guo; Jia-hui Cao; Yuan-kang Feng; Shu-ning Guo; Guo-hong Liu; Yi Ding; Yu-rong Chai (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Preliminary report on the improved resistance towards Pseudomonas syringae pv. actinidiae of cultivated kiwifruit (Actinidia chinensis) when grafted onto wild Actinidia guilinensis rootstock in vitro - Fa-ming Wang; Jie-wei Li; Kai-yu Ye; Hong-juan Gong; Ping-ping Liu; Qiao-sheng Jiang; Bei-bei Qi; Quan-hui Mo (Journal of Plant Pathology, 2021)

The reproductive regulation of LPXRFa and its receptor in the hypothalamo-pituitary-gonadal axis of the spotted scat (Scatophagus argus) - Yi Zhai; Si-Ping Deng; Jian-Ye Liu; Dong-Neng Jiang; Yang Huang; Chun-Hua Zhu; Guang-Li Li; Ming-Hui Li (Fish Physiology and Biochemistry, 2021)

Simultaneously decreased temporal variability and enhanced variability-strength coupling of emotional network connectivities are related to positive symptoms in patients with schizophrenia - Yanjia Deng; Shuguang Han; Dongliang Cheng; Hui Li; Bin Zhang; Youyong Kong; Yong Lin; Yingjia Li; Ge Wen; Kai Liu (Brain Imaging and Behavior, 2021)

Downregulation of miR-296-3p by highly pathogenic porcine reproductive and respiratory syndrome virus activates the IRF1/TNF-α signaling axis in porcine alveolar macrophages - Yanbing Zhang; Xiao Xiang; Yan Lu; Hui Li; Abdul Wahaab; Mona Sharma; Ke Liu; Jianchao Wei; Zongjie Li; Donghua Shao; Beibei Li; Zhiyong Ma; et al. (Archives of Virology, 2021)

A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization - Jinying Chen; Fan-Li Lin; Jacqueline Y. K. Leung; Leilei Tu; Jiang-Hui Wang; Yu-Fan Chuang; Fan Li; Hsin-Hui Shen; Gregory J. Dusting; Vickie H. Y. Wong; Leszek Lisowski; Alex W. Hewitt; et al. (Angiogenesis, 2021)

Mechanisms of high-frequency dinoflagellate blooms of Scrippsiella trochoidea in Daya Bay, South China Sea - Yuan Tian; Simin Hu; Xianzhi Lin; Hui Huang; Xingyu Song; Yan Yan; Xuedong Xie; Tao Li; Sheng Liu (Journal of Oceanology and Limnology, 2021)

The Effect of Composting on the Multiple Heavy Metals in the River Sediment Investigated by Multivariate Analysis - Yaoning Chen; Yanrong Chen; Yuanping Li; Yihuan Liu; Daoli Zhang; Yanxin Wu; Hui Li; Fangting Xu; Meiling Li (Water, Air, & Soil Pollution, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Partial recovery of disturbed V-J pairing profiles of T-cell receptor in people living with HIV receiving long-term antiretroviral therapy - Guoli Li; Jiarui Li; Henghui Zhang; Yu Zhang; Di Liu; Yu Hao; Junyan Han; Juan Du; Liuluan Zhu; Yongqin Zeng; Bei Li; Rui Li; et al. (Science China Life Sciences, 2021)

Identification and expression analysis of caffeoyl-coenzyme A O-methyltransferase family genes related to lignin biosynthesis in tea plant (Camellia sinensis) - Shi-Jia Lin; Ya-Zhuo Yang; Rui-Min Teng; Hao Liu; Hui Li; Jing Zhuang (Protoplasma, 2021)

Effects of shading on lignin biosynthesis in the leaf of tea plant (Camellia sinensis (L.) O. Kuntze) - Rui-Min Teng; Yong-Xin Wang; Hui Li; Shi-Jia Lin; Hao Liu; Jing Zhuang (Molecular Genetics and Genomics, 2021)

Advances in intervention methods and brain protection mechanisms of in situ and remote ischemic postconditioning - Chun-Yan Li; Wei Ma; Kuang-Pin Liu; Jin-Wei Yang; Xian-Bin Wang; Zhen Wu; Tong Zhang; Jia-Wei Wang; Wei Liu; Jie Liu; Yu Liang; Xing-Kui Zhang; et al. (Metabolic Brain Disease, 2021)

A Fluorogenic and Chromogenic Probe Distinguishes Fluoride Anions and Thiols: Implications for Discrimination of Fluoride-Containing G Series and Sulfur-Containing V Series Nerve Agents - Wei-hui Wu; Xin Wang; Liang Zong; Dan Li; Yan-hua Xiao; Shao-hui Sui; Jian Li; Meng Liu; Gao-yun Chen; Teng Luo; Min Liu; Xin-ming Wang; et al. (Journal of Fluorescence, 2021)

Improving the observation and prediction capabilities for Arctic marine environment: from the perspective of Arctic Shipping - Hui Wang; Qizhen Sun; Lin Zhang; Xi Liang; Qinghua Yang; Na Liu; Chunhua Li; Qingsheng Liu; Bingrui Li; Qian Feng; Xiao Cheng; Yi Yu (Acta Oceanologica Sinica, 2021)

Phosphorus addition decreases microbial residual contribution to soil organic carbon pool in a tropical coastal forest - Ye Yuan; Yue Li; Zhijian Mou; Luhui Kuang; Wenjia Wu; Jing Zhang; Faming Wang; Dafeng Hui; Josep Peñuelas; Jordi Sardans; Hans Lambers; Jun Wang; et al. (Global Change Biology, 2021)
The soil nitrogen (N) and phosphorus (P) availability often constrains soil carbon (C) pool, and elevated N deposition could further intensify soil P limitation, which may affect soil C cycling in these N‐rich and P‐poor ecosystems. Soil microbial residues may not only affect soil organic carbon (SOC) pool but also impact SOC stability through soil aggregation. However, how soil nutrient availability and aggregate fractions affect microbial residues and the microbial residue contribution to SOC is still not well understood. We took advantage of a 10‐year field fertilization experiment to investigate the effects of nutrient additions, soil aggregate fractions, and their interactions on the concentrations of soil microbial residues and their contribution to SOC accumulation in a tropical coastal forest. We found that continuous P addition greatly decreased the concentrations of microbial residues and their contribution to SOC, whereas N addition had no significant effect. The P‐stimulated decreases in microbial residues and their contribution to SOC were presumably due to enhanced recycling of microbial residues via increased activity of residue‐decomposing enzymes. The interactive effects between soil aggregate fraction and nutrient addition were not significant, suggesting a weak role of physical protection by soil aggregates in mediating microbial responses to altered soil nutrient availability. Our data suggest that the mechanisms driving microbial residue responses to increased N and P availability might be different, and the P‐induced decrease in the contribution of microbial residues might be unfavorable for the stability of SOC in N‐rich and P‐poor tropical forests. Such information is critical for understanding the role of tropical forests in the global carbon cycle.

Production of functional human nerve growth factor from the submandibular glands of mice using a CRISPR/Cas9 genome editing system - Yi Gu; Hui Cao; Fei Li; Jianli Yu; Rui Nian; Dongxiao Feng; Jingtao Lin; Haipeng Song; Wenshuai Liu (World Journal of Microbiology and Biotechnology, 2020)

Uncovering the mysterious identity of Taisui—an old Chinese folk legend - Erwei Li; Jinwei Ren; Qian Chen; Hanxing Zhang; Bin Lin; Hui Zhang; Shumin Zhang; Xiaoling Zhang; Lei Cai; Xingzhong Liu (Science China Life Sciences, 2020)

Inland fisheries development versus aquatic biodiversity conservation in China and its global implications - Hui Zhang; Jinming Wu; Harry Gorfine; Xiujuan Shan; Li Shen; Haile Yang; Hao Du; Junyi Li; Chengyou Wang; Qiong Zhou; Zhigang Liu; Myounghee Kang; et al. (Reviews in Fish Biology and Fisheries, 2020)

Neonatal curcumin treatment restores hippocampal neurogenesis and improves autism-related behaviors in a mouse model of autism - Hongyu Zhong; Rui Xiao; Ruotong Ruan; Hui Liu; Xin Li; Yun Cai; Jinghui Zhao; Xiaotang Fan (Psychopharmacology, 2020)

Carbon storage and plant-soil linkages among soil aggregates as affected by nitrogen enrichment and mowing management in a meadow grassland - Ruzhen Wang; Hui Wu; Jordi Sardans; Tianpeng Li; Heyong Liu; Josep Peñuelas; Feike A. Dijkstra; Yong Jiang (Plant and Soil, 2020)

ADP-ribosylation factors improve biomass yield and salinity tolerance in transgenic switchgrass (Panicum virgatum L.) - Cong Guan; Xue Li; Dan-Yang Tian; Hua-Yue Liu; Hui-Fang Cen; Million Tadege; Yun-Wei Zhang (Plant Cell Reports, 2020)

Correction to: Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Chang-Qi Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Silver(I) Coordination Polymers: Photocatalytic Properties and Enhanced Treatment Activity of Haloperidol on Children Tic Disorder by Regulating Neurotransmitter Content - Hui-Li Qian; Xin Yu; Guo-Feng Liu (Journal of Fluorescence, 2020)

Transcriptome-wide identification and profiling of miRNAs in a stress-tolerant conifer Sabina chinensis - Xian-Ge Hu; Shan-Shan Zhou; Ying Yang; Hui Liu; Shrestha Anil; Qing Wang; Wei Zhao; Qiong Gao; Yousry A El-Kassaby; Tongli Wang; Yue Li; Jian-Feng Mao (Journal of Biosciences, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Relationships among cigarette smoking, urinary biomarkers, and urothelial carcinoma risk: a case-control study - Chi-Jung Chung; Hui-Tsung Hsu; Chao-Hsiang Chang; Sheng-Wei Li; Chiu-Shong Liu; Mu-Chi Chung; Guo-Wei Wu; Wei-Ting Jung; Yen-Jung Kuo; Hui-Ling Lee (Environmental Science and Pollution Research, 2020)

Analyzing adaptation strategies for maize production under future climate change in Guanzhong Plain, China - Qaisar Saddique; Huanjie Cai; Jiatun Xu; Ali Ajaz; Jianqiang He; Qiang Yu; Yunfei Wang; Hui Chen; Muhammad Imran Khan; De Li Liu; Liang He (Mitigation and Adaptation Strategies for Global Change, 2020)

SNP of AHSA2 gene in three cattle breeds using snapshot technology - Shu-Zhu Cheng; E. Guang-Xin; Cheng-Li Liu; Wang-Dui Basang; Yan-Bin Zhu; Ri-Su Na; Yan-Guo Han; Yan Zeng; Xiao Wang; Wei-Wei Ni; Bai-Gao Yang; Xing-Hai Duan; et al. (Journal of Genetics, 2020)

Comparison of chemical characteristics of PM2.5 during two winters in Xiangtan City in south central China - Xiao-Yao Ma; Zheng-Hui Xiao; Li-Zhi He; Yun-Jiang Cao; Ji-Song Liu (Journal of Atmospheric Chemistry, 2020)

Transcriptome analysis following enterovirus 71 and coxsackievirus A16 infection in respiratory epithelial cells - Jie Song; Yajie Hu; Weiyu Li; Hui Li; Huiwen Zheng; Yanli Chen; Shaozhong Dong; Longding Liu (Archives of Virology, 2020)

Small Jellyfish as a Supplementary Autumnal Food Source for Juvenile Chaetognaths in Sanya Bay, China - Lingli Wang; Minglan Guo; Tao Li; Hui Huang; Sheng Liu; Simin Hu (Journal of Marine Science and Engineering, 2020)
Information on the in situ diet of juvenile chaetognaths is critical for understanding the population recruitment of chaetognaths and their functional roles in marine food web. In this study, a molecular method based on PCR amplification targeted on 18S rDNA was applied to investigate the diet composition of juvenile Flaccisagitta enflata collected in summer and autumn in Sanya Bay, China. Diverse diet species were detected in the gut contents of juvenile F. enflata, including copepods, small jellyfish, anthozoa, polychaetes, echinoderms, diatoms and dinoflagellates. The diet composition showed obvious differences between summer and autumn. Copepod, such as Temora turbinata, Canthocalanus pauper and Subeucalanus crassus, dominated the diet in summer, representing up to 61% of the total prey items. However, small jellyfish, mainly consisting of Bougainvillia fulva, Solmissus marshalli and Pleurobrachia globosa, was the main food group (72.9%) in autumn. Environmental parameters showed no significant difference between summer and autumn. The mean abundance of juvenile chaetognaths in autumn was about eight times higher than that in summer, while the abundance of potential food prey was similar in both seasons. Our results suggested that juveniles chaetognaths might consume small jellyfish as a supplementary food source under enhanced feeding competition in autumn.

WDR5a functions in cadmium-inhibited root meristem growth by regulating nitric oxide accumulation in Arabidopsis - Yu Zhang; Yang-Yang Tian; Lin-Feng Wang; Yun-Hui Li; Ting-Ting Li; Wen-Cheng Liu (Planta, 2020)

Vertical fine-root distributions in five subalpine forest types shifts with soil properties across environmental gradients - Fang Lan Li; M. Luke McCormack; Xin Liu; Hui Hu; De Feng Feng; Wei Kai Bao (Plant and Soil, 2020)

MiR-132-3p serves as a tumor suppressor in mantle cell lymphoma via directly targeting SOX11 - Baoyu Wu; Jingyu Li; Han Wang; Qian Wu; Hui Liu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)