Correction to: Involvement of regulation of the excitation:inhibition functional balance in the mPFC in the antidepressant-anxiolytic effect of YL-IPA08, a novel TSPO ligand - Jin Yuan; Jun-Qi Yao; Xin-Xin Fang; Wei Dai; Yun-Hui Wang; Li-Ming Zhang; Yun-Feng Li (Metabolic Brain Disease, 2022)

Association between gestational arsenic exposure and intrauterine growth restriction: the role of folate content - Fei-Xiang Xu; Xu Chen; Heng Zhang; Yi-Jun Fan; Ya-Ping Song; Jin-Wei Lv; Ya-Li Xie; Yichao Huang; Dao-Zhen Chen; Hua Wang; De-Xiang Xu (Environmental Science and Pollution Research, 2022)

Olivine and melt inclusion chemical constraints on the nature and origin of the common mantle component beneath eastern Asia - Jian-Qiang Liu; Li-Hui Chen; Xiao-Jun Wang; Hui-Li Zhang; Gang Zeng; Saskia Erdmann; Le Zhang; Zhong-Yuan Ren (Contributions to Mineralogy and Petrology, 2022)

Partial recovery of the left DLPFC-right insula circuit with reduced craving in abstinent heroin users: a longitudinal study - Shan Zhang; Wenhan Yang; Minpeng Li; Shicong Wang; Jun Zhang; Jun Liu; Kai Yuan (Brain Imaging and Behavior, 2022)

A modified TOPMODEL introducing the bedrock surface topographic index in Huangbengliu watershed, China - An-ni Qiu; Yan-jun Zhang; Gen-xu Wang; Jun Cui; Yuan-xin Song; Xiang-yang Sun; Li Chen (Journal of Mountain Science, 2022)

Time Domain Full Waveform Inversion Based on Gradient Preconditioning with an Angle-Dependent Weighting Factor - Dongming Xia; Peng Song; Xishuang Li; Jun Tan; Chuang Xie; Shaowen Wang; Kai Liu; Bo Zhao; Shibo Mao (Journal of Ocean University of China, 2022)

Visual cues and body volatile β-ocimene are used by the blue tiger butterfly Tirumala limniace to identify conspecifics during courtship - Chengzhe Li; Hua Wang; Xiaoming Chen; Jun Yao; Jianyu Deng (Behavioral Ecology and Sociobiology, 2022)

Immunogenicity and protective efficacy of a DNA vaccine inducing optimal expression of the SARS-CoV-2 S gene in hACE2 mice - Zhuo-xin Li; Sheng Feng; He Zhang; Xin-yu Zhuang; Chao Shang; Shi-yu Sun; Ji-cheng Han; Yu-biao Xie; Jin-yong Zhang; Wei Wang; Cheng-hui Li; Guan-yu Zhao; et al. (Archives of Virology, 2022)

CACNA1C-AS2 inhibits cell proliferation and suppresses cell migration and invasion via targeting FBXO45 and PI3K/AKT/mTOR pathways in glioma - Tong Cao; Yue Cui; Yingying Wang; Linhui Wu; Ke Yu; Kai Chen; Jun Xia; Yuyun Li; Zhiwei Peter Wang; Jia Ma (Apoptosis, 2022)

Morphological and histological changes in the brains of turbot (Scophthalmus maximus) with gonadal development - Chunyan Zhao; Liang Chi; Yongshuang Xiao; Bing Li; Yunliang Lu; Yanting Cui; Wenqi Wang; Jun Li (Acta Oceanologica Sinica, 2022)

In situ cultivation of deep-sea water with bicarbonate fueled a different microbial community - Yong Wang; Jun Li; Zhanfei Wei; Qingmei Li; Yingli Zhou; Wenli Li; Jun Chen; Suixue Wang; Yongzhi Xin; Aiqun Zhang (Acta Oceanologica Sinica, 2022)

Evaluation of nitrogen mineralization under various irrigation water qualities and nitrogen application rates for mulched drip irrigation in an arid region - Chao Ma; Jun Wang; Jiusheng Li (Irrigation and Drainage, 2022)
Understanding the interactive effects of irrigation water quality and fertilization on nitrogen mineralization ( N min ) and accurately predicting N min are of great importance for the secure and efficient utilization of brackish water in arid regions. A pot experiment was conducted to determine the N min under different drip irrigation water salinities and nitrogen application rates and to modify the nitrogen mineralization potential ( N 0 ) and mineralization rate constants ( k ) of the first‐order kinetic equation of N min . An in situ field experiment was conducted to validate the modified equation. The results showed that the amounts of N min for water salinities of 1.27, 3.03, and 4.90 g L −1 were 58.9, 76.1, and 45.4 kg ha −1 , respectively. N min was stimulated when the soil salinities were lower than 6.6, 6.1 and 3.9 g kg −1 for nitrogen application rates of 255, 315 and 375 kg ha −1 , respectively. Nitrogen application significantly reduced N min . When the nitrogen application rate increased to 375 kg ha −1 , the net N min rate remained lower, and the effects of salinity on N min were attenuated. The N min model with modified N 0 and k values was developed considering the impacts of soil organic nitrogen, nitrogen application rate, and soil salinity. Model testing indicated that the modified model provided an acceptable estimation of N min under field conditions. It will be helpful for developing rational fertilization strategies of drip irrigation with brackish water in arid regions.

Persistence and Ecological Impact of Ionic Liquids in Soil - Jingwen Zhang; Chengbo Lu; Bing Li; Albert Juhasz; Zhongkun Du; Lusheng Zhu; Jun Wang; Jinhua Wang (Current Pollution Reports, 2022)

Crustal electrical structure across the Tangra-Yumco tectonic belt revealed by magnetotelluric data: new insights on the east–west extension mechanism of the Tibetan plateau - Ning Chen; Xuben Wang; Changsheng Shao; Jun Zou; Zhengwei Xu; Dewei Li; Xiangpeng Wang (Acta Geophysica, 2022)

Typhoon-Resistant Performance Assessment of Coastal Rural Residential Keel Brick Walls Reinforced with High Ductility Concrete - Qiang Li; Jun Zhang; Rui Wang; Jing Liu; Ping Li (Journal of Marine Science and Engineering, 2022)
The keel brick wall belongs to the rural residential exterior wall unique to the southeast coastal region of China. The wooden keel inside the wall and the external tie members can improve the stability of the whole wall. However, due to the age of construction, the wooden keel inside the existing residential keel brick walls has basically rotted and lost the tie with the external members, which seriously reduces the stability of the whole wall. Moreover, the collapse of keel brick walls caused by typhoons has become more and more frequent in recent years, seriously endangering the lives and properties of residents. Therefore, it is necessary to carry out reinforcement and repair for the existing residential buildings with keel brick walls. In this paper, the keel brick walls of rural houses in Ningbo area were taken as the research object, a framework for evaluating the performance of keel brick walls against typhoons was established, tests on the lateral force resistance of keel brick walls reinforced with high ductility concrete and mortar were carried out. With the help of typhoon full-track simulation and wind field simulation technology, the 600-year near-surface typhoon wind speeds affecting Ningbo area were obtained. A joint probability distribution model of multi-directional extreme wind speed was constructed using t-Copula function to determine the mixed wind climate of Ningbo area. The extreme wind loads that keel brick walls can withstand under four types of reinforcement were finally given. The results show that the high ductility concrete reinforcement has great advantages over mortar reinforcement and avoids brittle damage of the masonry structure. The keel brick walls reinforced with single-sided mortar can withstand wind loads of a 3-year return period, the keel brick walls reinforced with single-sided high ductile concrete can withstand extreme wind loads of a 110-year return period, while the keel brick walls reinforced with double-sided mortar as well as double-sided high ductile concrete can withstand extreme wind loads of well over a 110-year return period.

CircHIPK3 promotes proliferation and metastasis of villous trophoblasts through miR-30a-3p/Wnt2 axis - Shuhong Li; Ning Li; Bing Li; Lili Zhu; Tingting Xu; Li Wang; Jun Zhang; Fanqiang Kong (Journal of Genetics, 2022)

Correction to: Soybean genetic resources contributing to sustainable protein production - Bingfu Guo; Liping Sun; Siqi Jiang; Honglei Ren; Rujian Sun; Zhongyan Wei; Huilong Hong; Xiaoyan Luan; Jun Wang; Xiaobo Wang; Donghe Xu; Wenbin Li; et al. (Theoretical and Applied Genetics, 2022)

Soybean genetic resources contributing to sustainable protein production - Bingfu Guo; Liping Sun; Siqi Jiang; Honglei Ren; Rujian Sun; Zhongyan Wei; Huilong Hong; Xiaoyan Luan; Jun Wang; Xiaobo Wang; Donghe Xu; Wenbin Li; et al. (Theoretical and Applied Genetics, 2022)
Key message Genetic resources contributes to the sustainable protein production in soybean. Abstract Soybean is an important crop for food, oil, and forage and is the main source of edible vegetable oil and vegetable protein. It plays an important role in maintaining balanced dietary nutrients for human health. The soybean protein content is a quantitative trait mainly controlled by gene additive effects and is usually negatively correlated with agronomic traits such as the oil content and yield. The selection of soybean varieties with high protein content and high yield to secure sustainable protein production is one of the difficulties in soybean breeding. The abundant genetic variation of soybean germplasm resources is the basis for overcoming the obstacles in breeding for soybean varieties with high yield and high protein content. Soybean has been cultivated for more than 5000 years and has spread from China to other parts of the world. The rich genetic resources play an important role in promoting the sustainable production of soybean protein worldwide. In this paper, the origin and spread of soybean and the current status of soybean production are reviewed; the genetic characteristics of soybean protein and the distribution of resources are expounded based on phenotypes; the discovery of soybean seed protein-related genes as well as transcriptomic, metabolomic, and proteomic studies in soybean are elaborated; the creation and utilization of high-protein germplasm resources are introduced; and the prospect of high-protein soybean breeding is described.

CAF-derived midkine promotes EMT and cisplatin resistance by upregulating lncRNA ST7-AS1 in gastric cancer - Ke-Da Yang; Ying Wang; Fan Zhang; Qing-Ling Li; Bai-Hua Luo; De-Yun Feng; Zhi-Jun Zeng (Molecular and Cellular Biochemistry, 2022)

The evaluation of Bacillus-secreted polyglutamic acid as anti-scaling treatment for circulating cooling water - Yutong Li; Zhen Yan; Jun Liu; Chao Song; Fanping Zhu; Shuguang Wang (Environmental Science and Pollution Research, 2022)

Hydrogeochemical characterization and water quality assessment in Altay, Xinjiang, northwest China - Juan-Qin Gao; Yang Yu; Deng-Hong Wang; Li-Jun Liu; Wei Wang; Hong-Zhang Dai; Kuang Cen (Environmental Monitoring and Assessment, 2022)

Effects of lead and cadmium co-exposure on liver function in residents near a mining and smelting area in northwestern China - Jun Yan; Honglong Zhang; Jingping Niu; Bin Luo; Haiping Wang; Meng Tian; Xun Li (Environmental Geochemistry and Health, 2022)

Dongia deserti sp. nov., Isolated from the Gurbantunggut Desert Soil - Chun-Yan Lu; Lei Dong; Dong Wang; Shuai Li; Bao-Zhu Fang; Ming-Xian Han; Feng Liu; Hong-Chen Jiang; Iftikhar Ahmed; Wen-Jun Li (Current Microbiology, 2022)

Complete genome analysis of a novel chuvirus from a southern green stink bug (Nezara viridula) - Peng-Peng Ren; Zhuang-Xin Ye; Sai-Nan Wang; Jun-Min Li; Jian-Ping Chen; Chuan-Xi Zhang; Jia-Bao Lu (Archives of Virology, 2022)

Paenibacillus hamazuiensis sp. nov., a bacterium isolated from Hamazui hot spring in Yunnan province, south-west China - Juan Wang; Ming Deng; En-Min Zhou; Lei Ran; Cui-Ping Miao; Yi-Qing Li; Jun-Mei Ding; Shu-Kun Tang (Archives of Microbiology, 2022)

Rare earth element characteristics of the Permian Lucaogou Formation shale in the Junggar Basin, Northwest China - Jun Yin; Li Wang; Haitao Lin; Yali Zhu (Arabian Journal of Geosciences, 2022)

Two new chemical constituents from Lonicera japonica - Jian-liang Geng; Hai-bo Li; Wen-jun Liu; Zhen-zhong Wang; Wen Ge; Wei Xiao (Natural Product Research, 2022)

Oxidative stress and DNA damage in earthworms induced by methyl tertiary-butyl ether in natural soils - Yanqiang Li; Jun Wang; Zhongkang Yang; Guangde Li; Zhongwen Zhang; Dexin Zhang; Hui Sun (Environmental Science and Pollution Research, 2022)

Sexual size dimorphism in golden pompano (Trachinotus blochii): Potential roles of changes in energy allocation and differences in muscle metabolism - Jun Long Sun; Fei Biao Song; Lei Wang; Wei Wei Zhang; You Ming Chen; Li Zhou; Jian Fang Gui; Jian Luo (Frontiers in Marine Science, 2022)
Golden pompano ( Trachinotus blochii ) is becoming increasingly popular and produces high yields, but the growth differences between males and females are a concern. In this study, the differences between the growth of males and females were compared, and the transcriptome analysis of muscle tissues was performed. A significant difference between the growth of males and females was observed; females were found to be 17% larger than males after reaching 7 months of age. Gonadal histological analysis revealed that the ovaries were arrested in 7- to 9-month-old golden pompano, whereas the testes continued to develop. The AMPK and adipocytokine signaling pathways were also found to be involved in the regulation of muscle growth and metabolism. After reaching 7 months of age, the expression levels of glut1 , glut4 , ldh , gys, acsl and cpt2 in the muscle of females were lower than those in males, but the hk gene, which is involved in glycolysis, was found to remain highly expressed in females. Additionally, in females, the synthesis of arginine and ornithine and the production of carnosine were found to be inhibited, but the breakdown of glutamine was found to be enhanced and OXPHOS ability was found to be stronger in females after reaching 7 months of age. These results support a certain negative correlation between gonadal development and muscle metabolism depending on differences in energy distribution. Clearly, the faster growth in females after reaching 7 months of age was found to be associated with the more active metabolism of glucose, and amino acids, as well as stronger oxidative phosphorylation levels.

Seismic Shot Gather Denoising by Using a Supervised-Deep-Learning Method with Weak Dependence on Real Noise Data: A Solution to the Lack of Real Noise Data - Xintong Dong; Jun Lin; Shaoping Lu; Xingguo Huang; Hongzhou Wang; Yue Li (Surveys in Geophysics, 2022)

Chili residue and Bacillus laterosporus synergy impacts soil bacterial microbiome and agronomic performance of leaf mustard (Brassica juncea L.) in a solar ﻿greenhouse - Ibraheem Olamide Olasupo; Jun Wang; Xiaoxuan Wei; Mintao Sun; Yansu Li; Xianchang Yu; Yan Yan; Chaoxing He (Plant and Soil, 2022)

Involvement of regulation of the excitation:inhibition functional balance in the mPFC in the antidepressant-anxiolytic effect of YL-IPA08, a novel TSPO ligand - Jin Yuan; Jun-Qi Yao; Xin-Xin Fang; Wei Dai; Yun-Hui Wang; Li-Ming Zhang; Yun-Feng Li (Metabolic Brain Disease, 2022)

Expression patterns and correlation analyses of muscle-specific genes in the process of sheep myoblast differentiation - Hejie Wang; Minmin Dou; Jun Li; Peng Cao; Junling Li; Tianyan Guo; Dipeng Zhao; Ajab Khan; Yingliang Li; Baojun Li; Jian Qin; Rong Du (In Vitro Cellular & Developmental Biology - Animal, 2022)

Comparative transcriptome analyses identify genes involved into the biosynthesis of forsythin and forsythoside A in Forsythia suspensa - Wang Jun Yuan; Su Ping Zhang; Zhi Yin He; Yan Xia He; She Qi He; Li Jun Liu; Xin Sun; Qin Li (Functional & Integrative Genomics, 2022)

Ambient gaseous pollutant exposure and incidence of visual impairment among children and adolescents: findings from a longitudinal, two-center cohort study in China - Li Chen; Jing Wei; Tao Ma; Di Gao; Xijie Wang; Bo Wen; Manman Chen; Yanhui Li; Jun Jiang; Lijuan Wu; Weiming Li; Xiangtong Liu; et al. (Environmental Science and Pollution Research, 2022)

Mycotoxin surveillance on wheats in Shandong province, China, reveals non-negligible probabilistic health risk of chronic gastrointestinal diseases posed by deoxynivalenol - Fenghua Li; Xinglan Duan; Liwen Zhang; Dafeng Jiang; Xianqi Zhao; En Meng; Ran Yi; Chang Liu; Yirui Li; Jia-Sheng Wang; Xiulan Zhao; Wei Li; et al. (Environmental Science and Pollution Research, 2022)

Knowledge domain and emerging trends of climate-smart agriculture: a bibliometric study - Jun Li; Enjun Xia; Lingling Wang; Kuan Yan; Li Zhu; Jieping Huang (Environmental Science and Pollution Research, 2022)

Investigating the environmental impacts of coal mining using remote sensing and in situ measurements in Ruqigou Coalfield, China - Varinder Saini; Jun Li; Yinan Yang; Jinsong Li; Baoming Wang; Jun Tan (Environmental Monitoring and Assessment, 2022)

Distribution, source, and health risk assessment of polycyclic aromatic hydrocarbons in the soils from a typical petroleum refinery area in south China - Wenmin Ma; Jian Hu; Jun Li; Jun Li; Peng Wang; Chukwunonso Peter Okoli (Environmental Monitoring and Assessment, 2022)

Sphingosinicella terrae sp. nov. Isolated from a Desert Soil and Reclassification of Sphingomonas deserti as Sphingosinicella deserti comb. nov. - Dong Wang; Lei Dong; Neeli Habib; Feng Liu; Sohail Ahmad Jan; Jian-Yu Jiao; Min Xiao; Nimaichand Salam; Wen-Jun Li (Current Microbiology, 2022)

Oceanobacillus saliphilus sp. nov., Isolated from Saline−Alkali Soil in Heilongjiang Province, China - Yu-Ting OuYang; Meng-Meng Li; Ai-Ping Lv; Pin-Jiao Jin; Lan Liu; Ze-Tao Liu; Jian-Yu Jiao; Wen-Jun Li; Li-Xiang Cao; Shuang Wang (Current Microbiology, 2022)

The effect of Fe–Ti oxide separation on iron isotopic fractionation during basalt differentiation - Jian Zhao; Xiao-Jun Wang; Li-Hui Chen; Takeshi Hanyu; Jin-Hua Shi; Xiao-Wen Liu; Hiroshi Kawabata; Lie-Wen Xie (Contributions to Mineralogy and Petrology, 2022)

Dynamic impact of boulders on different types of concrete dam - Zhu-jun Feng; Xiu-li Wang; Yong-hong Ran (Journal of Mountain Science, 2022)

Spatio-temporal variations and influencing factors of energy-related carbon emissions for Xinjiang cities in China based on time-series nighttime light data - Li Zhang; Jun Lei; Changjian Wang; Fei Wang; Zhifei Geng; Xiaoli Zhou (Journal of Geographical Sciences, 2022)

Complete genome analysis of a novel iflavirus from the spotted lanternfly Lycorma delicatula - Yi-Zhe Wang; Zhuang-Xin Ye; Jian‑Ping Chen; Chuan‑Xi Zhang; Jun‑Min Li; Hai-Jian Huang (Archives of Virology, 2022)

Paracandidimonas lactea sp. nov., a urea-utilizing bacterium isolated from landfill - Chu Zhang; Qian Pu; Jun-jie Ying; Ying Chen; Cheng-ze Li; Hang-tao Wu; Bin-jie Wang; Yu-han Zhang; Guo-hong Zeng; Ou Li; Xiu-fang Hu; Cong Sun (Archives of Microbiology, 2022)

Identification of terrigenous and autochthonous organic carbon in sediment cores from cascade reservoirs in the upper stream of Pearl River and Wujiang River, southwest China: lignin phenol as a tracer - Li Gao; Xin Lin; Jun Fan; Ming Yang; Xueping Chen; Fushun Wang; Jing Ma (Acta Geochimica, 2022)

Transcriptome analysis and co‐expression network reveal the mechanism linking mitochondrial function to immune regulation in red crucian carp ( Carassius auratus red var) after Aeromonas hydrophila challenge - Ning‐Xia Xiong; Xu‐Ying Kuang; Zi‐Xuan Fang; Jie Ou; Shi‐Yun Li; Jia‐Hui Zhao; Jin‐Fang Huang; Ke‐Xin Li; Rou Wang; Lan‐Fen Fan; Sheng‐Wei Luo; Shao‐Jun Liu (Journal of Fish Diseases, 2022)
Aeromonas hydrophila is a common pathogen of freshwater fish. In this study, A. hydrophila infection was shown to cause tissue damage, trigger physiological changes as well as alter the expression profiles of immune‐ and metabolic‐related genes in immune tissues of red crucian carp (RCC). Transcriptome analysis revealed that acute A. hydrophila infection exerted a profound effect on mitochondrial oxidative phosphorylation linking metabolic regulation to immune response. In addition, we further identified cellular senescence, apoptosis, necrosis and mitogen‐activated protein kinase signal pathways as crucial signal pathways in the kidney of RCC subjected to A. hydrophila infection. These findings may have important implications for understanding modulation of immunometabolic response to bacterial infection.

Corrigendum: Sea urchins in acute high temperature and low oxygen environments: The regulatory role of microRNAs in response to environmental stress - Lingshu Han; Yanglei Wu; Pengfei Hao; Beichen Ding; Yuanxin Li; Wenpei Wang; Xianglei Zhang; Chuang Gao; Heng Wang; Luo Wang; Weijie Zhang; Yaqing Chang; et al. (Frontiers in Marine Science, 2022)

Effect modification by aging on the associations of nicotine exposure with cognitive impairment among Chinese elderly - Jian Hou; Chao Huang; Bo Zhu; Wei Liu; Qing-qing Zhu; Lu Wang; Tian Li; Chun-jie Yuan; Shao-yang Lai; De-sheng Wu; Fei-qi Zhu; Jia-fei Zhang; et al. (Environmental Science and Pollution Research, 2022)

Aculeaquamide A, cytotoxic paraherquamide from the marine fungus Aspergillus aculeatinus WHUF0198 - Jun Wu; Fuqian Wang; Li-Ming He; Si-Yuan Zhou; Shou-Bao Wang; Jia Jia; Kui Hong; You-Sheng Cai (Natural Product Research, 2022)

Bioactivity-guided isolation of compounds from Sophora flavescens with antibacterial activity against Acinetobacter baumannii - Pin Li; Wern Chern Chai; Zhan-Yi Wang; Kai-Jun Tang; Jin-Yao Chen; Henrietta Venter; Susan J. Semple; Lan Xiang (Natural Product Research, 2022)

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

A urinary proteomic landscape of COVID-19 progression identifies signaling pathways and therapeutic options - Yuntao Liu; Lan Song; Nairen Zheng; Jinwen Shi; Hongxing Wu; Xing Yang; Nianci Xue; Xing Chen; Yimin Li; Changqing Sun; Cha Chen; Lijuan Tang; et al. (Science China Life Sciences, 2022)

Late Mesozoic rifting and its deep dynamic mechanisms in the central Sulu orogenic belt: Records from Lingshan Island - Tengfei Zhou; Yaoqi Zhou; Nina Søager; Paul Martin Holm; Zhenkai Zhang; Jun Wang; Zhao Liang; Hongyu Mu; Yanjun Cheng; Feifei Liu; Miao Wang; Yue Zhang; et al. (Science China Earth Sciences, 2022)

Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia - Kang-Wei Qian; Yun-Yun Li; Xiao-Hua Wu; Xue Gong; Ai-Lin Liu; Wen-Hao Chen; Zhe Yang; Ling-Jie Cui; Yun-Feng Liu; Yuan-Yuan Ma; Chen-Xi Yu; Furong Huang; et al. (Neuroscience Bulletin, 2022)

Pathological Networks Involving Dysmorphic Neurons in Type II Focal Cortical Dysplasia - Yijie Shao; Qianqian Ge; Jiachao Yang; Mi Wang; Yu Zhou; Jin-Xin Guo; Mengyue Zhu; Jiachen Shi; Yiqi Hu; Li Shen; Zhong Chen; Xiao-Ming Li; et al. (Neuroscience Bulletin, 2022)

Astrocyte-Derived TNF-α-Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating the RIP1/RIP3/AKT Signaling Pathway - Wei Li; Dengping Liu; Jiaqi Xu; Jun Zha; Chen Wang; Jianzhong An; Zhanli Xie; Shigang Qiao (Molecular Neurobiology, 2022)
Ischemic stroke is a clinical syndrome caused by the disruption of blood flow into cerebral tissues and is associated with high disability and mortality rates. Studies have established the pathological role of platelets in cerebral ischemia/reperfusion (I/R) injury, although the underlying mechanism of action remains largely unclear. In this study, we created an I/R mouse model via middle cerebral artery occlusion and reperfusion (MCAO/R) and analyzed the transcriptomic profiles of the ipsilateral and contralateral cortices using RNA-seq. We found that cerebral I/R injury induced platelet invasion and accumulation in the cerebral cortex by stimulating TNF-α secretion from activated astrocytes in the ischemic region, while TNF-α expression enhanced platelet reactivity through the RIP1/RIP3/AKT pathway. Furthermore, the inoculation of TNF-α-stimulated platelets aggravated I/R injury in mice, whereas the administration of anti-TNF-α antibodies at the onset of reperfusion alleviated ischemic damage. The RNA-seq results further showed that AP-1 transcriptionally activated TNF-α in the I/R-injured cortex by directly binding to the promoter region. These findings provide novel insights into the pathological role of platelets activated by reactive astrocyte-derived TNF-α in cerebral I/R injury.

Relationship between exposure to cadmium, lead, and mercury and the occurrence of urinary incontinence in women - Jinliang Ni; Ziye Li; Yi Lu; Houliang Zhang; Guangchun Wang; Jinbo Xie; Jun Xie; Yidi Wang; Yifan Zhang; Keyi Wang; Weipu Mao; Bo Peng (Environmental Science and Pollution Research, 2022)

Uncertainty or trust? Political trust, perceived uncertainty and public acceptance of personal carbon trading policy - Lan Gao; Jingjing Jiang; Haonan He; Qi Zhou; Shanyong Wang; Jun Li (Environmental Geochemistry and Health, 2022)

What drives resident acceptance of personal carbon trading policy in China? - Lan Gao; Haonan He; Shanyong Wang; Jun Li (Environmental Geochemistry and Health, 2022)

How can government environmental enforcement and corporate environmental responsibility consensus reduce environmental emergencies? - Liang Wan; Chengyuan Wang; Shanyong Wang; Jianing Zang; Jun Li (Environmental Geochemistry and Health, 2022)

The effect of environmental regulation competition on haze pollution: evidence from China’s province-level data - Li Li; Junwei Sun; Jingjing Jiang; Jun Wang (Environmental Geochemistry and Health, 2022)

Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota - Xian-Feng Yang; Shao-Chen Yang; Fu-Li Wen; Lin Feng; Bo Meng; Hai-Yan Hu; Bao-Lin Wang; Jun Li; Alexandre J. Poulain; Ping Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Occurrence of Phthalate Acid Esters (PAEs) in Protected Agriculture Soils and Implications for Human Health Exposure - Xianxu Li; Na Li; Can Wang; Anyu Wang; Wenjia Kong; Peipei Song; Jun Wang (Bulletin of Environmental Contamination and Toxicology, 2022)

The Effects of Lead and Cadmium Co-exposure on Serum Ions in Residents Living Near a Mining and Smelting Area in Northwest China - Qian Luo; Honglong Zhang; Haiping Wang; Li Ma; Min Huang; Jingping Niu; Bin Luo; Jun Yan; Xun Li (Biological Trace Element Research, 2022)

Correction to: Microvirga puerhi sp. nov., isolated from Puerh tea garden soil - Zhi-Da Zi; Wen Wen; Fu Ma; Wei Li; Zhao-Xuan Wang; Jun Lu; Jie Lv (Archives of Microbiology, 2022)

Hyphomonas sediminis sp. nov., isolated from marine sediment - Lu Wang; Wei He; Zeng-Yu Gao; Dao-Feng Zhang; Jian-Ke Huang; Chuang Liu; Wen-Jun Li; Ai Hua Zhang (Antonie van Leeuwenhoek, 2022)

Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors - Li-Ping Shen; Wei Li; Ling-Zhu Pei; Jun Yin; Shu-Tao Xie; Hong-Zhao Li; Chao Yan; Jian-Jun Wang; Qipeng Zhang; Xiao-Yang Zhang; Jing-Ning Zhu (The Cerebellum, 2022)

Spatio-temporal distribution and mechanism of Cenozoic magmatism in the South China Sea and adjacent areas: Insight from seismic, geochemical and geochronological data - Song Zhu; Yongjian Yao; Xuejie Li; Hongfang Gao; Jiangyong Zhang; Ziying Xu; Jun Wang (International Geology Review, 2022)

Synthesis and in vitro biological evaluation of novel dendrocandin analogue as potential anti-tumor agent - Jing-Yun Yan; Hao-Nan Yang; Ning Yang; Yin-Rong Xie; Xiu-Li Sun; Ye-Wei Huang; Cheng-Ting Zi; Xuan-Jun Wang; Jun Sheng (Natural Product Research, 2022)

Genetic basis underlying tiller angle in rice (Oryza sativa L.) by genome-wide association study - Shaoxing Bai; Jun Hong; Su Su; Zhikang Li; Wensheng Wang; Jianxin Shi; Wanqi Liang; Dabing Zhang (Plant Cell Reports, 2022)

The traditional uses, secondary metabolites, and pharmacology of Eleutherococcus species - Yue-Hui Huang; Jin-Tao Li; Ke Zan; Jun Wang; Qiang Fu (Phytochemistry Reviews, 2022)

Genome-Wide Transcriptomic Analysis Reveals the Gene Regulatory Network Controlled by SRL1 in Regulating Rice Leaf Rolling - Min Li; Xizhi Li; Liang Zhu; Pengbo Xue; Jinlin Bao; Beibei Zhou; Jian Jin; Jun Wang (Journal of Plant Growth Regulation, 2022)

CRIF1 promotes the progression of non-small-cell lung cancer by SIRT3- mediated deacetylation of PYCR1 - Qi Wang; Zhuolin Xie; Chang Li; Chun Xu; Cheng Ding; Sheng Ju; Jun Chen; Zihan Cui; Chen Chen; Biao Gu; Tengteng Wei; Jun Zhao (Journal of Molecular Histology, 2022)

Identification and expression of potential olfactory-related genes related to Niemann–Pick C2 protein and ionotropic receptors in Haemaphysalis longicornis - Yingying Cui; Jungang Wang; Qiyong Liu; Dongmei Li; Wen Zhang; Xiaobo Liu; Jun Wang; Xiuping Song; Feng Yao; Haixia Wu; Ning Zhao (Experimental and Applied Acarology, 2022)

Comparative low lethal effects of three insecticides on demographical traits and enzyme activity of the Spodoptera exigua (Hübner) - Muhammad Hafeez; Farman Ullah; Muhammad Musa Khan; Zhangqian Wang; Hina Gul; Xiaowei Li; Jun Huang; Junaid Ali Siddiqui; Muhammad Qasim; Rui-Long Wang; Muhammad Imran; Mohammed A. Assiri; et al. (Environmental Science and Pollution Research, 2022)

Microfluidic preparation of a novel phoxim nanoemulsion pesticide against Spodoptera litura - Zong-Nan Li; Yu-Xuan Zhang; Zhi-Ang Zhang; Lian-Han Pan; Ping Li; Yan Xu; Sheng Sheng; Fu-An Wu; Jun Wang (Environmental Science and Pollution Research, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Alterations to cognitive abilities and functional networks in rats post broad-band intense noise exposure - Xiao-Min Xu; Yu-Qun Zhang; Feng-Chao Zang; Chun-Qiang Lu; Li-Jie Liu; Jian Wang; Richard Salvi; Yu-Chen Chen; Gao-Jun Teng (Brain Imaging and Behavior, 2022)

Experimental investigation on debris flow resistance and entrainment characteristics: effects of the erodible bed with discontinuous grading - Pu Li; Jia-ding Wang; Kai-heng Hu; Hai-jun Qiu; Jia-lin Xie (Journal of Mountain Science, 2022)

Main controlling factors and enrichment model of a multi-layer tight sandstone gas reservoir: case study from the Linxing Gas Field, eastern Ordos Basin, Northern China - Weitao Wu; Jingzhou Zhao; Yingbin Wang; Mingqiang Guo; Heyuan Wu; Jun Li; Jiacheng Dang (Arabian Journal of Geosciences, 2022)

Effects of climate change on major elements of the hydrological cycle in Aksu River basin, northwest China - Peng Yang; Wenyu Wang; Jun Xia; Yaning Chen; Chesheng Zhan; Shengqing Zhang; Cai Wei; Xiangang Luo; Jiang Li (International Journal of Climatology, 2022)
Water resources systems in arid regions are sensitive to climate change, which critically impacts the water cycle. In this study, we applied historical hydrometeorological data, CMIP5 data, and a large‐scale hydrological model (Community Land Model–Distributed Time‐Variant Gain Model [CLM–DTVGM]) to study the impact of climate change on the hydrological cycle (i.e., runoff, actual evapotranspiration (ET a ), and terrestrial water storage [TWS]) under different scenarios at the Aksu River basin (ARB) located in the arid region of northwest China. The primary findings of this study: (a) As the determination coefficient ( R 2 ) and Nash–Sutcliffe efficiency coefficient (NSE) reached desirable levels ( R 2 ≥ 0.583, NSE ≥ 0.371, and root‐mean‐square error ≤ 155.727), the CLM–DTVGM achieved a better simulation of runoff in the ARB; under climate change, the runoff depth in the irrigation area became shallower and followed a decreasing trend, with a minimum depth of 0.5 mm and a significant decreasing trend of −8 mm·a −1 . (b) Along with changes in the precipitation and temperature of the baseline period (i.e., 1980–2010), runoff, ET a , and TWS were predicted to change significantly in future scenarios. (c) Climate change significantly impacted the historical runoff from the Shaliguilanke and Xiehela hydrological stations, with correlation coefficients larger than 0.9; however, the runoff from the Alaer hydrological station was not affected. However, runoff, ET a , and TWS in the ARB were very closely correlated with climate change in the future scenarios, with correlation coefficients exceeding 0.9. Related research in the future would be important for guiding the sustainable development of the ARB.

Improving protected area effectiveness through consideration of different human‐pressure baselines - Chun‐Ting Feng; Ming Cao; Fang‐Zheng Liu; Yue Zhou; Jin‐Hong Du; Li‐Bo Zhang; Wen‐Jie Huang; Jian‐Wu Luo; Jun‐Sheng Li; Wei Wang (Conservation Biology, 2022)
Previous assessments of the effectiveness of protected areas (PAs) focused primarily on changes in human pressure over time and did not consider the different human‐pressure baselines of PAs, thereby potentially over‐ or underestimating PA effectiveness. We developed a framework that considers both human‐pressure baseline and change in human pressure over time and assessed the effectiveness of 338 PAs in China from 2010 to 2020. The initial state of human pressure on PAs was taken as the baseline, and changes in human pressure index (HPI) were further analyzed under different baselines. We used the random forest models to identify the management measures that most improved effectiveness in resisting human pressure for the PAs with different baselines. Finally, the relationships between the changes in the HPI and the changes in natural ecosystems in PAs were analyzed with different baselines. Of PAs with low HPI baselines, medium HPI baselines, and high HPI baselines, 76.92% ( n =150), 11.11% ( n =12), and 22.86% ( n =8) , respectively, showed positive effects in resisting human pressure. Overall, ignoring human‐pressure baselines somewhat underestimated the positive effects of PAs, especially for those with low initial human pressure. For PAs with different initial human pressures, different management measures should be taken to improve effectiveness and reduce threats to natural ecosystems. We believe our framework is useful for assessing the effectiveness of PAs globally, and we recommend it be included in the Convention on Biological Diversity Post‐2020 Strategy.

Transition between Mycobacterium tuberculosis and nontuberculous mycobacteria in recurrent “tuberculosis” patients - Qing Li; Haoran Li; Jun An; Xuxia Zhang; Wei Wang; Yufeng Wang; Zhongtan Xue; Shanshan Li; Yu Pang (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Effects of Heavy Metal Ions on Microbial Reductive Dechlorination of 1, 2-Dichloroethane and Tetrachloroethene - Jingjing Wang; Xiuying Li; Jun Yan; Yi Yang (Frontiers in Marine Science, 2022)
Microbial reductive dechlorination has been considered an effective process for the clean-up of organohalide-contaminated sites. Heavy metal ions are commonly present as co-contaminants in various organohalide-contaminated sites. To understand the impacts of heavy metal ions on the environmental fate of organohalides, we investigated the effects of Zn 2+ , Cu 2+ and Cd 2+ on reductive dechlorination of tetrachloroethene (PCE) and 1,2-dichloroethane (1,2-DCA) in sediment microcosms and transferred enrichment cultures. PCE and 1,2-DCA-dechlorinating enrichment cultures could be consecutively transferred in the presence of up to 10 mg/L Cu 2+ or 10 mg/L Zn 2+ ; by comparison, up to 50 mg/L Cd 2+ had minor impacts on the microbial reductive dechlorination of PCE and 1,2-DCA. The inhibitory effects of tested heavy metal ions on microbial reductive dechlorination ranked in descending order are Zn 2+ , Cu 2+ , and Cd 2+ . Community profiling and principal component analysis indicate that the concentration and type of contaminants (e.g., heavy metal ions, organohalides) shaped the microbial community structure, an observation similar to a prior report. The enrichment of certain organohalide-respring bacteria (e.g., Dehalococcoides , Dehalogenimonas ) during continuous transfers exposed to heavy metal ions suggests that they are capable of tolerating high concentrations of heavy metal ions. Our findings provide insights into the impacts of heavy metal ions on microbial reductive dechlorination and may be helpful for in situ bioremediation at sites contaminated with organohalides and heavy metals.

Revealing Selection in Breeding and Genetic Characteristics of Economically Important Traits of New Species of Apostichopus Japonicas Based on Genome Resequencing and GWAS Analysis - Chao Guo; Yuanxin Li; Jiahui Xie; Lingshu Han; Youquan Wang; Xianglei Zhang; YangLei Wu; Jian Song; Yaqing Chang; Jun Ding (Frontiers in Marine Science, 2022)
Apostichopus japonicas is an economically important species with high nutritional value. However, our knowledge of its genetic diversity and the genetic changes that occurred during its domestication or trait selection is quite limited. In this study, the whole genomes of 254 A . japonicas samples were resequenced. Analyses of the population genetic structure revealed that the genetic diversity of A. japonicas in the north of China is generally high, there was no difference in the population structure among the six cultured populations, and they were divided into two subpopulations together with AY-1 (new species). The results also showed that the genetic diversity of the AY-1 population was relatively low, the degree of linkage of alleles was high, and this population had been subjected to more positive selection. Based on Tajima’s D, F ST analysis, and ROD analysis, the selected intervals and genes of the AY-1 population were identified, with some of the candidate intervals being related to an economically important trait and breeding target, namely, the number of parapodia. Gene Ontology analysis of the candidate genes revealed that the two subpopulations differed in their immune function, protein synthesis, decomposition, and transport, among others. Using GWAS, we identified 39 candidate genes for four economically important traits of A. japonicas , and we verified that those genes contained non-synonymous SNPs. Through this verification, BSL78_00022 and BSL78_00023 were found to be key genes for the number of parapodia in A. japonicas . Of these two genes, BSL78_00022 encodes a protein related to cell differentiation and proliferation, so it was assumed that three non-synonymous substitutions (Ser-Phe, Glu-Asp, and Ala-Val) in this gene are related to the changes in the number of parapodia. Meanwhile, the pleiotropic gene BSL78_04631, which is related to body weight and body wall weight, and promotes protein synthesis and cell growth, has a non-synonymous substitution (IlE-Val), which is assumed to be the reason for the difference in body weight and body wall weight of A. japonicas . These results provide a new perspective for explaining the genetic structure characteristics of A. japonicas and analyzing the selection and economically important traits in the breeding of new species.

Effects of 3,6-Dibromocarbazole on Soil Health—Based on Soil Enzymes and the Biolog-ECO Test - Zhongkun Du; Ji Zhang; Chao Cheng; Baihui Shi; Lusheng Zhu; Jun Wang; Jinhua Wang; Bing Li (Water, Air, & Soil Pollution, 2022)

Experimental Investigation of Decoupled Charge Effect on Rock Fragmentation by Blasting - Li Yuan Chi; Cheng Wang; Zong-Xian Zhang; Xuan Xu; Jun Yang (Rock Mechanics and Rock Engineering, 2022)

Intensified rainfall in the wet season alters the microbial contribution to soil carbon storage - Jinge Zhou; Jingfan Zhang; Hans Lambers; Jingtao Wu; Guoming Qin; Yingwen Li; Yongxing Li; Zhian Li; Jun Wang; Faming Wang (Plant and Soil, 2022)

lncRNAs MALAT1 and LINC00657 upstream to miR-214-3p/BMP2 regulate osteogenic differentiation of human mesenchymal stem cells - Jun Li; He Zhuang; Zhe Wang; Jun Cai; Xinqiang Ma; Wenxiang Chen; Xibing Jiang; Dongsheng Zhao; Wangjun Hou; Yewei Tao (Molecular Biology Reports, 2022)

Design and synthesis of ludartin derivatives as potential anticancer agents against hepatocellular carcinoma - Jin-Jin Sun; Jin-Ping Wang; Tian-Ze Li; Yun-Bao Ma; Dong Xue; Ji-Jun Chen (Medicinal Chemistry Research, 2022)

Identification of a major stable QTL for spikelet number in wheat (Triticum aestivum L.) and its genetic effects analysis on yield-related traits - Mingsu Cao; Jizi Dong; Hao Wang; Yibiao Cai; Tianhang Ma; Xiaohan Zhou; Jingguo Xiao; Shihui Li; Linqu Chen; Huiyuan Xu; Chunhua Zhao; Yongzhen Wu; et al. (Euphytica, 2022)

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

Uptake and accumulation of naphthalene, phenanthrene, and benzo(b)fluoranthene in winter wheat affected by foliar exposure at different growth stages - Jinfeng Wang; Huanyu Bao; Jun Cai; Jia Li; Jiao Li; Fuyong Wu (Environmental Science and Pollution Research, 2022)

Magnetization of Bauxite Residue to Enhance the Removal Efficiency Towards Heavy Metals - Chuxuan Li; Jingju Zhou; Jun Jiang; Huagang Lv; Jun Wang; Dewen He (Bulletin of Environmental Contamination and Toxicology, 2022)

Oct4 facilitates chondrogenic differentiation of mesenchymal stem cells by mediating CIP2A expression - Lexiang Li; Qiwei Fu; Jiahua Shao; Bo Wang; Zheru Ding; Shuai Yuan; Jinhui Peng; Wei Xin; Jun Zhu; Yi Chen (Cell and Tissue Research, 2022)

Proposal for transfer Bacillus alkalicola to the genus Evansella as Evansella alkalicola comb. nov - Manik Prabhu Narsing Rao; Shuang Wang; Haijie Wang; Ying-Qian Kang; Wen-Jun Li (Archives of Microbiology, 2022)

Microvirga puerhi sp. nov., isolated from Puerh tea garden soil - Zhi-Da Zi; Wen Wen; Fu Ma; Wei Li; Zhao-Xuan Wang; Jun Lu; Jie Lv (Archives of Microbiology, 2022)

Pelagic cyanobacterial nitrogen fixation in lakes and ponds of different latitudinal zones - Yan Li; Ye-Xin Yu; Shuo-Nan Ma; Rui-Ting Qiao; Yong-De Cui; Hai-Jun Wang; Hong-Zhu Wang (Aquatic Sciences, 2022)

Stiripentol Enteric Solid Dispersion-Loaded Effervescent Tablets: Enhanced Dissolution, Stability, and Absorption - Ying Wang; Siyuan Xu; Ziyue Xiao; Yuxin Jiang; Qi Jiang; Jun Li; Wei He (AAPS PharmSciTech, 2022)

Historical biogeography of the gingers and its implications for shifts in tropical rain forest habitats - Jian‐Li Zhao; Xiang‐Qin Yu; W. John Kress; Ya‐Li Wang; Yong‐Mei Xia; Qing‐Jun Li (Journal of Biogeography, 2022)
Aim The relationships between biome shifts and global environmental changes in temperate zone habitats have been extensively explored; yet, the historical dynamics of taxa found in the tropical rain forest (TRF) remain poorly known. This study aims to reconstruct the relationships between tropical rain forest shifts and global environmental changes through the patterns of historical biogeography of a pantropical family of monocots, the Zingiberaceae. Location Global. Taxon Zingiberaceae. Methods We sampled DNA sequences (nrITS, trn K, trn L‐ trn F and psb A‐ trn H) from GenBank for 77% of the genera, including 30% of species, in the Zingiberaceae. Global fossil records of the Zingiberaceae were collected from literatures. Rates of speciation, extinction and diversification were estimated based on phylogenetic data and fossil records through methods implemented in BAMM. Ancestral ranges were estimated using single‐tree BioGeoBEARS and multiple‐trees BioGeoBEARS in RASP. Dispersal rate through time and dispersal rate among regions were calculated in R based on the result of ancestral estimation. Results The common ancestor of the Zingiberaceae likely originated in northern Africa during the mid‐Cretaceous, with later dispersal to the Asian tropics. Indo‐Burma, rather than Malesia, was likely a provenance of the common ancestor of Alpinioideae–Zingiberoideae. Several abrupt shifts of evolutionary rates from the Palaeocene were synchronized with sudden global environmental changes. Main conclusions Integrating phylogenetic patterns with fossil records suggests that the Zingiberaceae dispersed to Asia through drift of the Indian Plate from Africa in the late Palaeocene. Formation of island chains, land corridors and warming temperatures facilitated the emigration of the Zingiberaceae to a broad distribution across the tropics. Moreover, dramatic fluctuations of the speciation rate of Zingiberoideae appear to have been synchronized with global climate fluctuations. In general, the evolutionary history of the Zingiberaceae broadens our understanding of the association between TRF shifts in distribution and past global environmental changes, especially the origin of TRF in Southeast Asia.

Sea Urchins in Acute High Temperature and Low Oxygen Environments: The Regulatory Role of microRNAs in Response to Environmental Stress - Lingshu Han; Yanglei Wu; Pengfei Hao; Beichen Ding; Yuanxin Li; Wenpei Wang; Xianglei Zhang; Chuang Gao; Heng Wang; Luo Wang; Weijie Zhang; Yaqing Chang; et al. (Frontiers in Marine Science, 2022)
Strongylocentrotus intermedius is an economically valuable sea urchin species in China. However, its growth and survival are severely constrained by ocean warming and the hypoxia that often accompanies high water temperatures. MicroRNAs (miRNAs) are important regulators of gene expression in response to environmental change. In this study, high-throughput RNA sequencing was used to investigate changes in miRNA expression in S. intermedius under heat (25°C), hypoxia (2 mg/L O 2 ), and combined heat and hypoxia stresses. Twelve small RNAs libraries were constructed and 17, 14, and 23 differentially expressed miRNAs (DEMs) were identified in the heat, hypoxia, and combined stress groups ( P <0.05), respectively. Gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway functional analyses of putative target genes of the DEMs suggested that these miRNAs were important in basal metabolism, apoptosis, oxidative stress, and immune-related pathways. By co-analysis with published transcriptome data, key DEMs (miR-193, miR-184, miR-133, miR-125, miR-2008) and their key target genes ( EGF3 , ABCB4 , CYCL , PAN2 , CALN ) were identified. Quantitative real-time PCR analysis of the expression of 10 DEMs and their key target genes confirmed the RNA sequencing results. These results provide information on gene expression regulation of the molecular mechanisms underlying the response of S. intermedius to multi-cause environmental stresses.

Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells - Zhangyu Yao; Xiang Li; Jun Gao; Yutao Wang; Linmei Xiao; Xinxia Chang; Fangzhou Liu; Zhenqing Feng; Xiao Zhang (Human Cell, 2022)

Response of Size-Fractionated Chlorophyll a to Upwelling and Kuroshio in Northeastern South China Sea - Danyang Li; Shuang Yang; Yuqiu Wei; Xingzhou Wang; Yingjie Mao; Congcong Guo; Jun Sun (Journal of Marine Science and Engineering, 2022)
The variability of size-fractionated chlorophyll a (Chl a) biomass and related environmental variables was investigated in a survey conducted in the northeastern South China Sea (NESCS), to assess their responses to upwelling, Kuroshio, and nutrients in the summer of 2017. The depth-weighted total Chl a concentration varied from 0.057 to 0.496 μg/L. The contribution of size-fractionated Chl a to total Chl a biomass was determined, with the contributions of pico-Chl a (0.2–2 μm), nano-Chl a (2–20 μm), and micro-Chl a (>20 μm) found to be 52.87%, 38.54%, and 8.59%, respectively. We found that nano-Chl a contributes more to total-Chl a than pico-Chl a in areas affected by upwelling. In addition, the results indicated an upward shift in the deep chlorophyll maximum (DCM) content in the upwelling area and the Kuroshio intrusion area. The Chl a biomass was increased in the physical process. Overall, correlation analysis showed that environmental variables (temperature, salinity, phosphate, silicate, nitrate, nitrite, ammonium) significantly influenced the phytoplankton biomass. However, physical processes determined the changes in environmental variables, with upwelling and Kuroshio being the main factors regulating the distribution of Chl a.

The Motion and Deformation of Viscoplastic Slide while Entering a Body of Water - Zhenzhu Meng; Xueyou Li; Shoujie Han; Xiao Wang; Jun Meng; Zhipeng Li (Journal of Marine Science and Engineering, 2022)
Landslide-generated waves are hazards that, commonly, exist in the natural world. The motion and deformation of a submerged landslide significantly affect the efficiency of the momentum transfer, between the slide material and the water body, and, thereby, dominate the characteristics of the associated waves. Therefore, investigating how the submerged sliding mass is moved and deformed is of great importance, not only for understanding the physical mechanism behind the slide–water interaction but also for optimizing the predictive models of the wave characteristics. In this study, we assumed the landslide as a viscoplastic fluid and used an ideal viscoplastic material, called Carbopol, to mimic a natural landslide, at the laboratory scale. We, first, determined the coordinates of three control points, including the frontal point, deepest point, and center of mass, so as to quantify the time evolution of the submerged slide motion. We, then, fit the maximums of the coordinates of the control points with an integrated parameter of the incoming landslide, with the support of experimental data. Results indicated that not only the wave features but also the submerged slide motion can be quantified by the slide parameters on impact.

Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities - Lu Luo; Jun Yang; Cheng Wang; Jie Wu; Yafang Li; Xu Zhang; Hui Li; Hui Zhang; Yumei Zhou; Aiping Lu; Shilin Chen (Science China Life Sciences, 2022)

Revealing the Modular Similarities and Differences Among Alzheimer’s Disease, Vascular Dementia, and Parkinson’s Disease in Genomic Networks - Yafei Chen; Qiong Liu; Jun Liu; Penglu Wei; Bing Li; Nongyun Wang; Zhenquan Liu; Zhong Wang (NeuroMolecular Medicine, 2022)

Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat - Dong Peng; Han-Zi Qiao; Hong-Yu Tan; Yi-Xue Wang; Dan Luo; Li-Jun Qiao; Ye-Feng Cai; Shi-Jie Zhang; Qi Wang; Li Guan (Metabolic Brain Disease, 2022)

Application of Exogenous KH2PO4 and Salicylic Acid and Optimization of the Sowing Date Enhance Rice Yield Under High-Temperature Conditions - Jun Yang; Licheng Duan; Haohua He; Yingchun Li; Xiangxiang Li; Dan Liu; Jianjun Wang; Guohua Jin; Shue Huang (Journal of Plant Growth Regulation, 2022)

Neurovascular abnormalities in retinopathy of prematurity and emerging therapies - Chang Dai; Jun Xiao; Chenguang Wang; Wei Li; Guanfang Su (Journal of Molecular Medicine, 2022)

Testing the isotopic equilibrium fractionation on active speleothem based on cave monitoring - Yang-Yang Huang; Ting-Yong Li; Chao-Jun Chen; Ran Huang; Tao Wang; Yao Wu; Si-Ya Xiao; Yu-Zhen Xu; Hai-Ying Qiu; Yan Yang; Jun-Yun Li (Journal of Earth System Science, 2022)

Novel insights for PI3KC3 in mediating lipid accumulation in yellow catfish Pelteobagrus fulvidraco - Mei-Qin Zhuo; Jun Chen; Mei-Li Wu; Wen-Biao Wang (Fish Physiology and Biochemistry, 2022)

Experimental study on coal dust wettability strengthened by surface active ionic liquids - Weiqing Zhang; Qiang Hu; Shuguang Jiang; Li Wang; Jun Chai; Jingxin Mei (Environmental Science and Pollution Research, 2022)

Impacts of nanoplastics on life-history traits of marine rotifer (Brachionus plicatilis) are recovered after being transferred to clean seawater - Dong Wang; Shaoguo Ru; Wei Zhang; Zhenzhong Zhang; Yuejiao Li; Lingchao Zhao; Lianxu Li; Jun Wang (Environmental Science and Pollution Research, 2022)

FLO8 deletion leads to decreased adhesion and virulence with downregulated expression of EPA1, EPA6, and EPA7 in Candida glabrata - Jun-Tao Zhao; Ke-Zhi Chen; Jin-Yan Liu; Wei-Hua Li; Yu-Zhu Wang; Lu-Ling Wang; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2022)

Therapeutic Effects of Sodium Para-Aminosalicylic Acid on Cognitive Deficits and Activated ERK1/2-p90RSK/NF-κB Inflammatory Pathway in Pb-Exposed Rats - Li-li Lu; Yu-wen Zhang; Zhao-cong Li; Yuan-yuan Fang; Lei-lei Wang; Yue-song Zhao; Shao-jun Li; Shi-yan Ou; Michael Aschner; Yue-ming Jiang (Biological Trace Element Research, 2022)

Alternate freezing and thawing enhanced the sediment and nutrient runoff loss in the restored soil of the alpine mining area - Fa-Yong Li; Ren-jie Luo; Yong-jun You; Xue-fei Hu; Xiao-yan Qian; Peng-yan Zhang; Shan Wang; Guo-yu Li; Mohamed Eltohamy Kamel (Journal of Mountain Science, 2022)

The Impact of Urban Expansion on Plant Diversity Change in Karst Regions of Southwest China - Shengtian Yang; Chaojun Li; Hezhen Lou; Ya Luo; Pengfei Wang; Jun Zhang; Xi Li; Xijin Wu (Chinese Geographical Science, 2022)

Re-evaluation of the identities of Glossadelphus borneensis and its associated synonyms, G. attenuatus and G. nitidus - Zhao-Qin Yi; Si He; Jun-Jie Wang; Li-Qiang Mu; Yu Jia (Brittonia, 2022)

Associations between species-level indoor microbiome, environmental characteristics, and asthma in junior high schools of Terengganu, Malaysia - Xi Fu; Yi Meng; Yanling Li; Xunhua Zhu; Qianqian Yuan; Aminnuddin Ma’pol; Jamal Hisham Hashim; Zailina Hashim; Gunilla Wieslander; Yi-Wu Zheng; Xu-Xin Lai; Michael Dho Spangfort; et al. (Air Quality, Atmosphere & Health, 2022)

Natural component plumbagin as a potential antibacterial agent against Streptococcus agalactiae infection - Ai‐Guo Huang; Lin‐Jun Su; Wei‐Hao He; Fa‐Li Zhang; Chao‐Shuai Wei; Ying‐Hui Wang (Journal of Fish Diseases, 2022)
Streptococcus agalactiae , also known as Group B Streptococcus (GBS), can infect humans, terrestrial animals and fish. The emergence of bacterial resistance of S. agalactiae to antibiotics leads to an urgent need of exploration of new antimicrobial agents. In the study, the antibacterial activity of natural component plumbagin (PLB) against S. agalactiae was investigated in vitro and in vivo. The results showed that the minimal inhibitory concentration (MIC) of PLB against S. agalactiae was 8 mg/L. The growth curve assay revealed that PLB could inhibit the growth of S. agalactiae . In addition, the time‐killing curve showed that S. agalactiae was killed almost completely by 2‐fold MIC of PLB within 12 h. Transmission electron microscopy results showed obvious severe morphological destruction and abnormal cells of S. agalactiae after treated with PLB. The pathogenicity of S. agalactiae to zebrafish was significantly decreased after preincubation with PLB for 2 h in vitro, further indicating the bactericidal activity of PLB. Interestingly, PLB could kill S. agalactiae without inducing resistance development. Furthermore, pretreatment and post‐treatment assays suggested that PLB also exhibited the antibacterial activity against S. agalactiae infection in vivo by effectively reducing the bacterial load and improving the survival rate of S. agalactiae ‐infected zebrafish. In summary, PLB had potent antibacterial activity against S. agalactiae in vitro and in vivo, and it could be an excellent antimicrobial candidate to prevent and control S. agalactiae infection.

Functional diversity loss and change in nocturnal behavior of mammals under anthropogenic disturbance - Xueyou Li; Wenqiang Hu; William V. Bleisch; Quan Li; Hongjiao Wang; Wen Lu; Jun Sun; Fuyou Zhang; Bu Ti; Xuelong Jiang (Conservation Biology, 2022)
In the Anthropocene, understanding the impacts of anthropogenic influence on biodiversity and behavior of vulnerable wildlife communities is increasingly relevant to effective conservation. However, comparative studies aimed at disentangling the concurrent effect of different types of human disturbance on multifaceted biodiversity and on activity patterns of mammals are surprisingly rare. We applied a multiregion community model to separately estimate the effects of cumulative human modification (e.g., settlement, agriculture, and transportation) and human presence (aggregated presence of dogs, people, and livestock) on species richness and functional composition of medium‐ and large‐bodied mammals based on camera trap data collected across 45 subtropical montane forests. We divided the detected mammal species into three trophic guilds–carnivores, herbivores, and omnivores–and assessed the nocturnal shifts of each guild in response to anthropogenic activities. Overall, species richness tended to increase ( β coefficient = 0.954) as human modification increased but richness decreased as human presence increased ( β = –1.054). Human modification was associated with significantly lower functional diversity (mean nearest taxon distance [MNTD], β = –0.134; standardized effect sizes of MNTD, β = –0.397), community average body mass ( β = –0.240), and proportion of carnivores ( β = –0.580). Human presence was associated with a strongly reduced proportion of herbivores ( β = –0.522), whereas proportion of omnivores significantly increased as human presence ( β = 0.378) and habitat modification ( β = 0.419) increased. In terms of activity patterns, omnivores ( β = 12.103) and carnivores ( β = 9.368) became more nocturnal in response to human modification. Our results suggest that human modification and human presence have differing effects on mammals and demonstrate that anthropogenic disturbances can lead to drastic loss of functional diversity and result in a shift to nocturnal behavior of mammals. Conservation planning should consider concurrent effects of different types of human disturbance on species richness, functional diversity, and behavior of wildlife communities.

Retraction Note: Bimatoprost-Loaded Silica Shell–Coated Nanoparticles-Laden Soft Contact Lenses to Manage Glaucoma: In Vitro and In Vivo Studies - He Xiaojie; Jiang Fagang; Jing Jun; Wang Chunfang; Li Chengquan; Wang Xinghua (AAPS PharmSciTech, 2022)

Revealing the Effectiveness of Fisheries Policy: A Biological Observation of Species Johnius belengerii in Xiamen Bay - Liang-Min Huang; Jia-Qiao Wang; Yi-Jia Shih; Jun Li; Ta-Jen Chu (Journal of Marine Science and Engineering, 2022)
The rapid development of China’s economy has brought tremendous pressure to the marine ecosystem, and about 57% of marine fish populations have been overexploited or collapsed. A series of fisheries policies have been implemented successively to improve the decline of resources. Over the past decade, the fisheries sector has particularly increased focus on resource and ecosystem sustainability, which has led to the wider use of stock management policies in China. Therefore, fishery resource assessment is crucial, such as assessing the long-term changes in biological information. This study is based on biological characteristics of Johnius belengerii captured by bottom trawls in Xiamen Bay during two periods, beginning in 2006 and 2016. Length composition, length–weight relationship, growth, mortality, sexual maturation, and feeding intensity were analyzed. The changes in biological characteristics show that there is a phenomenon of improvement in the later period, of which the changes are closely related to a series of fisheries management strategies, such as setting closed fishing periods and non-fishing areas, and establishing fishery restoration marine protected areas. This result seems to reveal the effectiveness of a long-term series of fisheries policies. It can provide an important basis and visibility for management effectiveness.

Anti-hyperglycaemic effect of labdane diterpenes isolated from the rhizome of Amomum maximum Roxb., an edible plant in Southwest China - Chuan-Li Lu; Li-Ning Wang; Ya-Jun Li; Qing-Fei Fan; Qing-Hua Huang; Jun-Jia Chen (Natural Product Research, 2022)

Prediction Method and Validation Study of Tensile Performance of Reinforced Armor Layer in Marine Flexible Pipe/Cables - Hualin Wang; Zhixun Yang; Jun Yan; Gang Wang; Dongyan Shi; Baoshun Zhou; Yanchun Li (Journal of Marine Science and Engineering, 2022)
Marine flexible pipe/cables, such as umbilicals, flexible pipes and cryogenic hoses, are widely adopted in ocean engineering. The reinforcing armor layer in these pipe/cables is the main component for bearing loads, which is a typical multi-layer helically wound slender structure with different winding angles for different devices. There has been no general theoretical methodology to describe the tensile performance of these flexible pipe/cables. This paper first introduces a theory to solve the tensile mechanical behavior of a helically wound structure. Based on the curved beam theory, a solution of the tensile stress of a helically wound slender is derived. Then, the deformation mechanism of the marine flexible pipe/cables structure with different winding angles is studied. Through comparing theoretical and numerical results, the deformation characteristic of the helically wound slender structure is further explained. It is found that a sectional torsional deformation generates when the structure with a larger winding angle is under tension condition, while the sectional deformation of the structure with a smaller winding angle is mainly tension. Finally, a couple types of marine flexible pipe/cables under the tension condition are provided to analyze the mechanical performance and compare the difference between different theoretical models. The research conclusion from this paper provides a useful reference for the structural analysis and design of marine flexible pipe/cables.

Numerical simulation and cause analysis of persistent summer drought during the 1920s in eastern China - Meng Luo; Jinming Feng; Zhongfeng Xu; Jun Wang; Li Dan (Science China Earth Sciences, 2022)

Multiple indeterminate domain (IDD)–DELLA1 complexes participate in gibberellin feedback regulation in peach - Yajun Jiang; Jiajia Chen; Xianbo Zheng; Bin Tan; Xia Ye; Wei Wang; Langlang Zhang; Jidong Li; Zhiqian Li; Jun Cheng; Jiancan Feng (Plant Molecular Biology, 2022)

Mutation of Beclin1 acetylation site at K414 alleviates high glucose-induced podocyte impairment in the early stage of diabetic nephropathy by inhibiting hyperactivated autophagy - Jun Xu; Yujie Deng; Yingying Ke; Yunxia Zhu; Ping Wang; Qing Yu; Chengqian Li; Bimin Shi (Molecular Biology Reports, 2022)

Kai-Xin-San Inhibits Tau Pathology and Neuronal Apoptosis in Aged SAMP8 Mice - Ya-Nan Jiao; Jing-Sheng Zhang; Wen-Jun Qiao; Shu-Yu Tian; Yi-Bin Wang; Chun-Yan Wang; Yan-Hui Zhang; Qi Zhang; Wen Li; Dong-Yu Min; Zhan-You Wang (Molecular Neurobiology, 2022)
Alzheimer’s disease (AD) is an age-related neurological disorder. Currently, there is no effective cure for AD due to its complexity in pathogenesis. In light of the complex pathogenesis of AD, the traditional Chinese medicine (TCM) formula Kai-Xin-San (KXS), which was used for amnesia treatment, has been proved to improve cognitive function in AD animal models. However, the active ingredients and the mechanism of KXS have not yet been clearly elucidated. In this study, network pharmacology analysis predicts that KXS yields 168 candidate compounds acting on 863 potential targets, 30 of which are associated with AD. Enrichment analysis revealed that the therapeutic mechanisms of KXS for AD are associated with the inhibition of Tau protein hyperphosphorylation, inflammation, and apoptosis. Therefore, we chose 7-month-old senescence-accelerated mouse prone 8 (SAMP8) mice as AD mouse model, which harbors the behavioral and pathological hallmarks of AD. Subsequently, the potential underlying action mechanisms of KXS on AD predicted by the network pharmacology analyses were experimentally validated in SAMP8 mice after intragastric administration of KXS for 3 months. We observed that KXS upregulated AKT phosphorylation, suppressed GSK3β and CDK5 activation, and inhibited the TLR4/MyD88/NF-κB signaling pathway to attenuate Tau hyperphosphorylation and neuroinflammation, thus suppressing neuronal apoptosis and improving the cognitive impairment of aged SAMP8 mice. Taken together, our findings reveal a multi-component and multi-target therapeutic mechanism of KXS for attenuating the progression of AD, contributing to the future development of TCM modernization, including KXS, and broader clinical application. Graphical abstract

Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model - Wan-yi Li; Jun-yan Gao; Su-Yang Lin; Shao-tao Pan; Biao Xiao; Yu-tao Ma; Kai Xie; Wei Shen; Zhi-tao Liu; Guang-yu Li; Jie-jie Guo; Qin-wen Wang; et al. (Molecular Neurobiology, 2022)

Correction to: Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Effects of Shellfish and Macro-Algae IMTA in North China on the Environment, Inorganic Carbon System, Organic Carbon System, and Sea–Air CO2 Fluxes - Yi Liu; Jihong Zhang; Wenguang Wu; Yi Zhong; Hongmei Li; Xinmeng Wang; Jun Yang; Yongyu Zhang (Frontiers in Marine Science, 2022)
Shellfish and macro-algae integrated multi-trophic aquaculture (IMTA) contribute greatly to the sustainability of aquaculture. However, the effects of large-scale shellfish and macro-algae aquaculture on the functions of the ocean carbon sink are not clear. To clarify these effects, we studied the spatial and temporal changes of inorganic and organic carbon systems in seawater under different aquaculture modes (monoculture or polyculture of shellfish and macro-algae) in Sanggou Bay, together with the variation of other environmental factors. The results show that the summertime dissolved oxygen (DO) concentration in the shellfish culture zone was significantly lower than other zones ( p < 0.05), with a minimum value of 7.07 ± 0.25 mg/L. The variation of pH and total alkalinity (TA) were large across different culture modes, and the seawater in the shellfish culture zone had the lowest pH and TA than the other zones. Seasonal environment and aquaculture modes significantly affected the variation of dissolved inorganic carbon (DIC), CO 2 partial pressure ( p CO 2 ), dissolved organic carbon (DOC), and particulate organic carbon (POC) concentrations. The highest values of DIC, p CO 2 , and POC appeared in summer, and the lowest appeared in winter. For DOC concentration, the lowest value appeared in autumn. Spatially, DIC and p CO 2 were highest in the shellfish culture zone and lowest in the macro-algae culture zone, DOC was highest in the macro-algae culture zone and lowest in the shellfish culture zone, and POC was lower in the shellfish culture zone and macro-algae culture zone and higher in the remaining zones. The results of sea–air CO 2 fluxes showed that except for the shellfish culture zone during summertime, which released CO 2 to the atmosphere, all culture zones were the sinks of atmospheric CO 2 during the culture period, with the whole bay being a strong CO 2 sink during autumn and winter. In summary, large-scale shellfish–macro-algae IMTA plays an important role in the local carbon cycle and contributes to mitigating ocean acidification and hypoxia.

Full-Length Transcriptome Data for the White Cloud Mountain Minnow (Tanichthys albonubes) From a Wild Population Based on Isoform Sequencing - Chao Li; Shenhang Zhong; Jinjin Jin; Han Xiao; Junjie Wang; Jun Zhao (Frontiers in Marine Science, 2022)

Dilatancy behaviour of rockfill materials and its description - Wan-Li Guo; Zheng-Yin Cai; Ying-Li Wu; Chen Zhang; Jun-Jie Wang (European Journal of Environmental and Civil Engineering, 2022)

Dissection of the practical soybean breeding pipeline by developing ZDX1, a high-throughput functional array - Rujian Sun; Bincheng Sun; Yu Tian; Shanshan Su; Yong Zhang; Wanhai Zhang; Jingshun Wang; Ping Yu; Bingfu Guo; Huihui Li; Yanfei Li; Huawei Gao; et al. (Theoretical and Applied Genetics, 2022)
Key message We developed the ZDX1 high-throughput functional soybean array for high accuracy evaluation and selection of both parents and progeny, which can greatly accelerate soybean breeding. Abstract Microarray technology facilitates rapid, accurate, and economical genotyping. Here, using resequencing data from 2214 representative soybean accessions, we developed the high-throughput functional array ZDX1, containing 158,959 SNPs, covering 90.92% of soybean genes and sites related to important traits. By application of the array, a total of 817 accessions were genotyped, including three subpopulations of candidate parental lines, parental lines and their progeny from practical breeding. The fixed SNPs were identified in progeny, indicating artificial selection during the breeding process. By identifying functional sites of target traits, novel soybean cyst nematode-resistant progeny and maturity-related novel sources were identified by allele combinations, demonstrating that functional sites provide an efficient method for the rapid screening of desirable traits or gene sources. Notably, we found that the breeding index (BI) was a good indicator for progeny selection. Superior progeny were derived from the combination of distantly related parents, with at least one parent having a higher BI. Furthermore, new combinations based on good performance were proposed for further breeding after excluding redundant and closely related parents. Genomic best linear unbiased prediction (GBLUP) analysis was the best analysis method and achieved the highest accuracy in predicting four traits when comparing SNPs in genic regions rather than whole genomic or intergenic SNPs. The prediction accuracy was improved by 32.1% by using progeny to expand the training population. Collectively, a versatile assay demonstrated that the functional ZDX1 array provided efficient information for the design and optimization of a breeding pipeline for accelerated soybean breeding.

Application of acid protease in the industrial production of corn ethanol - Liangliang Wang; Qi Yao; Jun Yue; Xirui Jiang; Fangfang Li (Systems Microbiology and Biomanufacturing, 2022)

The solar wind plasma upstream of Mars observed by Tianwen-1: Comparison with Mars Express and MAVEN - Kai Fan; Limei Yan; Yong Wei; Aibing Zhang; Linggao Kong; Markus Fränz; Fei He; Lihui Chai; Chongjing Yuan; Yuqi Wang; Jun Zhong; Zhaojin Rong; et al. (Science China Earth Sciences, 2022)

HaCYC2c regulating the heteromorphous development and functional differentiation of florets by recognizing HaNDUA2 in sunflower - Zhuoyuan He; Wenjing Zeng; Weiying Chen; Yichao Wu; Guoqin Wen; Xitong Chen; Qian Wang; Jiayan Zhou; Yunxiang Li; Zaijun Yang; Jian Zou; Jun Yang (Plant Cell Reports, 2022)

Crocin Alleviates Intracerebral Hemorrhage–Induced Neuronal Ferroptosis by Facilitating Nrf2 Nuclear Translocation - Fei Wang; Wu-lin Li; Li-juan Shen; Ting-ting Jiang; Jian-jun Xia; Da-li You; Shan-you Hu; Li Wang; Xiao Wu (Neurotoxicity Research, 2022)

Melatonin inhibits autophagy in TM3 cells via AKT/FOXO1 pathway - Zhiqiang Li; Hongtao Wang; Kaiyan Zhang; Jing Zhao; Hongyu Liu; Xin Ma; Jing Guo; Jun Wang; Wenfa Lu (Molecular Biology Reports, 2022)

Cassiterite oxygen isotopes in magmatic-hydrothermal systems: in situ microanalysis, fractionation factor, and applications - Yang Li; Sheng He; Rong-Qing Zhang; Xian-Wu Bi; Lian-Jun Feng; Guo-Qiang Tang; Wen-Zhong Wang; Fang Huang; Xian-Hua Li (Mineralium Deposita, 2022)

Dihydroartemisinin ameliorates chronic nonbacterial prostatitis and epithelial cellular inflammation by blocking the E2F7/HIF1α pathway - Yan Zhou; Jun-hao Wang; Jian-peng Han; Jian-yong Feng; Kuo Guo; Fei Du; Wen-bin Chen; Yong-zhang Li (Inflammation Research, 2022)

Cloning and expression of kiss genes and regulation of feeding in Siberian sturgeon (Acipenser baerii) - Shaoqi Xu; Mei Wang; Ya Li; Ni Tang; Xin Zhang; Hu Chen; Shupeng Zhang; Yanling Liu; Jun Wang; Defang Chen; Zhiqiong Li (Fish Physiology and Biochemistry, 2022)

Short-term effect of ambient air pollutant change on the risk of tuberculosis outpatient visits: a time-series study in Fuyang, China - Xin-Qiang Wang; Ying-Qing Li; Cheng-Yang Hu; Kai Huang; Kun Ding; Xiao-Jing Yang; Xin Cheng; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Yong-Zhong Zhang; Zhen-tao Ding; et al. (Environmental Science and Pollution Research, 2022)

Research on Transfer Rate of Heavy Metals and Harmful Elements in Traditional Chinese Medicine Extraction and Refining Processes and Product Health Risk Assessment - Dujia Jin; Lin Li; Wujun Dong; Xiangyang Zhu; Xuejun Xia; Renyun Wang; Jun Ye; Ran Li; Zhihua Liu; Xueqing Xu; Lili Gao; Yuling Liu; et al. (Biological Trace Element Research, 2022)

An evaluation method for internal erosion potential of gravelly soil based on particle size distribution - Qin Zhu; Li-jun Su; Zhen-yu Liu; Bin Wang (Journal of Mountain Science, 2022)

Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma - Peipei Han; Shu Wu; Limei Li; Danping Li; Jun Zhao; Haishan Zhang; Yifang Wang; Xuemin Zhong; Zhe Zhang; Ping Li; Liudmila Matskova; Xiaoying Zhou (Genes & Genomics, 2022)

Complete genome sequence of a novel arlivirus from a yellow spotted stink bug (Erthesina fullo (Thunberg, 1783)) - Zhuang-Xin Ye; Shao-Min Wang; Gang Lu; Jian-Ping Chen; Chuan-Xi Zhang; Liao-Yuan Xu; Jun-Min Li (Archives of Virology, 2022)

Investigation on Natural Infection of Covert Mortality Nodavirus in Large Yellow Croaker, Larimichthys crocea - Tingting Xu; Yuding Fan; Tianchang Jia; Chong Wang; Wei Wang; Jun Li; Qingli Zhang; Cuiluan Yao (Frontiers in Marine Science, 2022)
Covert mortality nodavirus (CMNV) recently became more prevalent, severely affecting farmed shrimps, and also other invertebrates and teleost fish, in the coastal areas of China. For better understanding of its prevalence and susceptibility of large yellow croaker Larimichthys crocea to CMNV, an epidemiological survey was carried out in the main producing areas (Ningbo, Zhejiang, China, and Ningde, Fujian, China) and its offshore feeding grounds in the Southern Yellow Sea. The collected cultured L. crocea individuals showed clinical symptoms such as anorexia and abnormal swimming and diagnosed for CMNV infection by using RT-nPCR assay. The positive rates for CMNV in the collected L. crocea samples from Ningbo, Ningde, and the Yellow Sea were 14.29% (4/28), 20.00% (7/35), and 16.67% (1/6), respectively. Furthermore, CMNV diagnosis using TaqMan probe-based reverse transcription quantitative PCR (TaqMan RT-qPCR) yielded positive rates of 25.00% (7/28), 22.86% (8/35), and 16.67% (1/6) respectively in the above-mentioned samples, and with a range of 12.73–3,108.33 of CMNV copy numbers/μg total RNA. Phylogenetic tree analysis based on the RNA-dependent RNA polymerase (RdRp) and capsid protein genes showed that CMNV isolates from L. crocea samples were clustered tightly with the original isolate of CMNV from Penaeus vannamei . The histopathological studies indicated that severe cellular necrosis occurred in the heart, liver, spleen, eye, and gill of naturally infected fish. Stronger positive signals for CMNV-specific probes appeared in the necrotic cells and tissues in the in situ hybridization (ISH) analysis. Transmission electron microscopy (TEM) revealed the presence of numerous 30 nm diameter CMNV-like viral particles. The purified CMNV suspension could cause a significant cytopathic effect (CPE) in epithelioma papilloma cyprini (EPC) cells and resulted in the formation of typical inclusion bodies, and also visible CMNV particles around the lysed EPC cells under the TEM. Taken together, all results of this study demonstrated that L. crocea is susceptible to CMNV. The prevalence of CMNV and its potential impacts on the wild population of L. crocea see the need for further investigations.

Petrogenesis and tectonic setting of the early-middle triassic subduction-related granite in the eastern segment of East Kunlun: evidences from petrology, geochemistry, and zircon U-Pb-Hf isotopes - Zuo-Chen Li; Xian-Zhi Pei; Paul D. Bons; Rui-Bao Li; Lei Pei; Guo-Chao Chen; You-Xin Chen; Cheng-Jun Liu; Meng Wang; Shao-Wei Zhao; Xiao-Bing Li; Feng Gao (International Geology Review, 2022)

Influence of initial water content and strain rate on remolded yield stress in marine clay - Xiaobing Li; Jianpeng Chen; Xiuqing Hu; Hongtao Fu; Jun Wang; Xueyu Geng (Marine Georesources & Geotechnology, 2022)

Transcriptomic analyses reveal the effect of nitric oxide on the lateral root development and growth of mangrove plant Kandelia obovata - Ming-Yue Wei; Huan Li; You-Hui Zhong; Zhi-Jun Shen; Dong-Na Ma; Chang-Hao Gao; Yi-Ling Liu; Wen-Hua Wang; Jing-Ya Zhang; Yan-Ping You; Hai-Lei Zheng (Plant and Soil, 2022)

RhoGEF Trio Regulates Radial Migration of Projection Neurons via Its Distinct Domains - Chengwen Wei; Mengwen Sun; Xiaoxuan Sun; Hu Meng; Qiongwei Li; Kai Gao; Weihua Yue; Lifang Wang; Dai Zhang; Jun Li (Neuroscience Bulletin, 2022)
The radial migration of cortical pyramidal neurons (PNs) during corticogenesis is necessary for establishing a multilayered cerebral cortex. Neuronal migration defects are considered a critical etiology of neurodevelopmental disorders, including autism spectrum disorders (ASDs), schizophrenia, epilepsy, and intellectual disability (ID). TRIO is a high-risk candidate gene for ASDs and ID. However, its role in embryonic radial migration and the etiology of ASDs and ID are not fully understood. In this study, we found that the in vivo conditional knockout or in utero knockout of Trio in excitatory precursors in the neocortex caused aberrant polarity and halted the migration of late-born PNs. Further investigation of the underlying mechanism revealed that the interaction of the Trio N-terminal SH3 domain with Myosin X mediated the adherence of migrating neurons to radial glial fibers through regulating the membrane location of neuronal cadherin (N-cadherin). Also, independent or synergistic overexpression of RAC1 and RHOA showed different phenotypic recoveries of the abnormal neuronal migration by affecting the morphological transition and/or the glial fiber-dependent locomotion. Taken together, our findings clarify a novel mechanism of Trio in regulating N-cadherin cell surface expression via the interaction of Myosin X with its N-terminal SH3 domain. These results suggest the vital roles of the guanine nucleotide exchange factor 1 (GEF1) and GEF2 domains in regulating radial migration by activating their Rho GTPase effectors in both distinct and cooperative manners, which might be associated with the abnormal phenotypes in neurodevelopmental disorders.

CAV1 is a prognostic predictor for patients with idiopathic pulmonary fibrosis and lung cancer - Dongdong Yin; Jiayang Qiu; Suxia Hu; Longqiang Cheng; Hui Li; Xingpu Cheng; Shun Wang; Jun Lu (Journal of Biosciences, 2022)

Determination of threshold soil salinity with consideration of salinity stress alleviation by applying nitrogen in the arid region - Zheng Che; Jun Wang; Jiusheng Li (Irrigation Science, 2022)

Circular RNA circ_0008934 promotes hepatocellular carcinoma growth and metastasis through modulating miR-1305/TMTC3 axis - Jia-Xi Li; Jin-Jiang Wang; Zhou-Feng Deng; Hao Zheng; Chun-Mei Yang; Ying Yuan; Cheng Yang; Fang-Fang Gu; Wei-Qi Wu; Guang-Lei Qiao; Li-Jun Ma (Human Cell, 2022)

Population pharmacokinetics of valproic acid in adult Chinese patients with bipolar disorder - Yan-Nan Zang; Wei Guo; Meng-Xi Niu; Shuang Bao; Qian Wang; Yan Wang; Fang Dong; An-Ning Li; Can-Jun Ruan (European Journal of Clinical Pharmacology, 2022)

NTA-assisted mineral element and lead transportation in Eremochloa ophiuroides (Munro) Hack - Siyi Pu; Xinyi Cai; Wenjuan Wang; Xingke Liu; Shangguan Li; Jingyi Fu; Lingxia Sun; Jun Ma; Mingyan Jiang; Xi Li (Environmental Science and Pollution Research, 2022)

Spatial Spillover Effects of Renewable Energy on Carbon Emissions in Less-developed Areas of China - Jun Bai; Shixiang Li; Qiying Kang; Nan Wang; Kailu Guo; Jinfeng Wang; Jinhua Cheng (Environmental Science and Pollution Research, 2022)

Same total normal forms sperm counts of males from Lhasa and Shanghai, China - Benhong Gu; Shangren Wang; Feng Liu; Yuxuan Song; Jun Li; Yongtao Ni; Min Chen; Jianlin Hu; Luobu Ouzhu; Zheng Li; Li Liu; Xia Li; et al. (Environmental Science and Pollution Research, 2022)

Is Zooplankton Body Size an Indicator of Water Quality in (Sub)tropical Reservoirs in China? - Li Wang; Jun Chen; Haojie Su; Xufa Ma; Zhixu Wu; Hong Shen; Jia Yu; Jiarui Liu; Yao Wu; Guangyi Ding; Ping Xie (Ecosystems, 2022)

Load transfer laws of tensile anchors in rock masses with weak interlayers based on a shear-slipping updating model - Yan Wang; Xin Xiang; Chang-dong Li; Guo-qiang Zhu; Cheng-bin Song; Jin-ye Xian; Jia-jun Zhang (Journal of Mountain Science, 2022)

Haloterrigena gelatinilytica sp. nov., a new extremely halophilic archaeon isolated from salt-lake - Bing-Bing Liu; Nimaichand Salam; Manik Prabhu Narsing Rao; Shuang Cheng; Yuan-Guo Xie; Lai-You Wang; Yuan-ru Zhang; Xin-Yuan Yu; Shu-xian Guo; Wen-Jun Li (Archives of Microbiology, 2022)

Can artificial light promote submerged macrophyte growth in summer? - Chao Xu; Hai-Jun Wang; Yan Li; Chi Xu; Qing Yu; Miao Liu; Miao Zhang; Hong-Zhu Wang; David P. Hamilton; Erik Jeppesen (Aquatic Ecology, 2022)

Seismic high-resolution processing method based on spectral simulation and total variation regularization constraints - Guo Xin; Gao Jian-Hu; Yin Xun-De; Yong Xue-Shan; Wang Hong-Qiu; Li Sheng-Jun (Applied Geophysics, 2022)

Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Dysfunction of FadA‐cAMP signalling decreases Aspergillus flavus resistance to antimicrobial natural preservative Perillaldehyde and AFB1 biosynthesis - Kunlong Yang; Qingru Geng; Yue Luo; Rui Xie; Tongzheng Sun; Zhen Wang; Ling Qin; Wei Zhao; Man Liu; Yongxin Li; Jun Tian (Environmental Microbiology, 2022)
Summary Aspergillus flavus is an opportunistic fungal pathogen that colonizes agriculture crops with aflatoxin contamination. We found that Perillaldehyde (PAE) effectively inhibited A . flavus viability and aflatoxin production by inducing excess reactive oxygen species (ROS). Transcriptome analysis indicated that the Gα protein FadA was significantly induced by PAE. Functional characterization of FadA showed it is important for asexual development and aflatoxin biosynthesis by regulation of cAMP‐PKA signalling. The Δ fadA mutant was more sensitive to PAE, while Δ pdeL and Δ pdeH mutants can tolerate excess PAE compared to wild‐type A . flavus . Further RNA‐sequence analysis showed that fadA was important for expression of genes involved in oxidation–reduction and cellular metabolism. The flow cytometry and fluorescence microscopy demonstrated that Δ fadA accumulated more concentration of ROS in cells, and the transcriptome data indicated that genes involved in ROS scavenging were downregulated in Δ fadA mutant. We further found that FadA participated in regulating response to extracellular environmental stresses by increasing phosphorylation levels of MAPK Kinase Slt2 and Hog1. Overall, our results indicated that FadA signalling engages in mycotoxin production and A . flavus resistance to antimicrobial PAE, which provide valuable information for controlling this fungus and AF biosynthesis in pre‐ and postharvest of agricultural crops.

Interactions and associated resistance development mechanisms between microplastics, antibiotics and heavy metals in the aquaculture environment - Zhen Li; Muhammad Junaid; Guanglong Chen; Jun Wang (Reviews in Aquaculture, 2022)
Microplastics (MPs), antibiotics and heavy metals unavoidably contaminate the aquaculture environment, with serious ecological and human health consequences. Antibiotic‐resistance genes (ARGs) and metal resistance genes (MRGs) are induced in microorganisms in the environment as a defence mechanism against antibiotics and heavy metals respectively. Furthermore, heavy metals in the aquaculture environment will cause bacteria to employ antibiotic resistance through co‐selection (co‐resistance or cross‐resistance) and other potential mechanisms. MPs may also act as potential carriers of multidrug resistance in aquaculture environments because they are hotspots for the enrichment and transmission of antibiotic resistance. Multidrug‐resistant (MDR) microorganisms in the aquaculture environment may infiltrate aquatic organisms via the food chain (eg MDR‐microorganisms→myctophids→ tuna/ squid/ whales/ seabirds/ seals), and after long‐term enrichment, they may gain access to the human body, posing a major risk to aquaculture and human health. As a result, this review article summarises contamination of MPs, heavy metal and antibiotics in global aquaculture settings; discusses the generation of ARGs, MRGs and common selection mechanisms for resistance development and emphasises the role of MPs as hot spots for antibiotic‐resistance selective enrichment, as well as potential carriers of multi‐drug‐resistant genes (MDRGs), in the aquaculture environment, posing an increasing threat to aquaculture and even human health.

Four new prenylflavonol glycosides from the leaves of Cyclocarya paliurus - Zi-Jun Ye; Hui-Hui Sun; Zu-Hui Chen; Jian-Ping Wu; Jing Li; Hui Zhu; Lu-Lu Huang; Xi-Wen Chang; Sai-Yu Ou; Wen-Xuan Wang; Xiao-Ai He; Gang-Zhi Zhu; et al. (Natural Product Research, 2022)

Genome-wide genetic diversity and IBD analysis reveals historic dissemination routes of pear in China - Xuening Chen; Mingyue Zhang; Manyi Sun; Yueyuan Liu; Shengnan Li; Bobo Song; Mengyan Li; Shaoling Zhang; Runze Wang; Jiaming Li; Kejiao Zhao; Jun Wu (Tree Genetics & Genomes, 2022)

The Relationship of Morphological-Hemodynamic Characteristics, Inflammation, and Remodeling of Aneurysm Wall in Unruptured Intracranial Aneurysms - Qingyuan Liu; Yisen Zhang; Junhua Yang; Yi Yang; Maogui Li; Shanwen Chen; Pengjun Jiang; Nuochuan Wang; Yanan Zhang; Jia Liu; Jun Wu; Shuo Wang (Translational Stroke Research, 2022)

Identification and characterization of QTL for spike morphological traits, plant height and heading date derived from the D genome of natural and resynthetic allohexaploid wheat - Huanwen Xu; Runqi Zhang; Mingming Wang; Linghong Li; Lei Yan; Zhen Wang; Jun Zhu; Xiyong Chen; Aiju Zhao; Zhenqi Su; Jiewen Xing; Qixin Sun; et al. (Theoretical and Applied Genetics, 2022)

Cancer metabolism and tumor microenvironment: fostering each other? - Yiyuan Yuan; Huimin Li; Wang Pu; Leilei Chen; Dong Guo; Hongfei Jiang; Bo He; Siyuan Qin; Kui Wang; Na Li; Jingwei Feng; Jing Wen; et al. (Science China Life Sciences, 2022)

Litter nitrogen concentration changes mediate effects of drought and plant species richness on litter decomposition - Jiang Wang; Yuan Ge; Johannes H. C. Cornelissen; Xiao-Yan Wang; Song Gao; Yi Bai; Tong Chen; Zhong-Wang Jing; Chong-Bang Zhang; Wen-Li Liu; Jun-Min Li; Fei-Hai Yu (Oecologia, 2022)

Circ_0001588 Upregulates ERBB4 to Promote Glioma Malignant Progression Through Sponging miR-1281 - Jun Wang; Juan Li; Peng Duan; Yanwei Dang; Tao Shi (Neurotoxicity Research, 2022)

A Reliable Murine Model of Disseminated Infection Induced by Talaromyces Marneffei - Juan He; Jia-Sheng Li; Hong-Yan Xu; Yi-Qun Kuang; Jun Li; Hong-Bin Li; Zhe Li; Hui-Ling Zhou; Rui-Rui Wang; Yu-Ye Li (Mycopathologia, 2022)

Reference gene selection for quantitative RT-PCR in Miscanthus sacchariflorus under abiotic stress conditions - Junqin Zong; Jingbo Chen; Ling Li; Jianjian Li; Dandan Li; Jingjing Wang; Jun Liu; Jianxiu Liu (Molecular Biology Reports, 2022)

The relationship between health expenditure, CO2 emissions, and economic growth in the BRICS countries—based on the Fourier ARDL model - Fangjhy Li; Tsangyao Chang; Mei-Chih Wang; Jun Zhou (Environmental Science and Pollution Research, 2022)

High-resolution dynamical downscaling for regional climate projection in Central Asia based on bias-corrected multiple GCMs - Yuan Qiu; Jinming Feng; Zhongwei Yan; Jun Wang; Zhen Li (Climate Dynamics, 2022)

Yohimbine Directly Induces Cardiotoxicity on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes - Yiqi Gong; Li Yang; Jun Tang; Jijian Zheng; Nevin Witman; Philipp Jakob; Yao Tan; Minglu Liu; Ying Chen; Huijing Wang; Wei Fu; Wei Wang (Cardiovascular Toxicology, 2022)

Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout - Ya-Wei Geng; Zhen Zhang; Han Jin; Jun-Long Da; Kai Zhang; Jian-Qun Wang; Yu-Yao Guo; Bin Zhang; Ying Li (Genes & Genomics, 2022)

Impact of caterpillars and plant-parasitic nematodes on Chinese tallow tree are more strongly affected by nematode density than by caterpillar identity - Sha Yang; Wenfeng Guo; Jun Tang; Wei Wang; Qingbiao Wu; Xiaoqiong Li (Arthropod-Plant Interactions, 2022)

Oxidation of organoarsenicals and antimonite by a novel flavin monooxygenase widely present in soil bacteria - Jun Zhang; Jian Chen; Yi‐Fei Wu; Zi‐Ping Wang; Ji‐Guo Qiu; Xiao‐Long Li; Feng Cai; Ke‐Qing Xiao; Xiao‐Xu Sun; Barry P. Rosen; Fang‐Jie Zhao (Environmental Microbiology, 2022)
Summary Arsenic can be biomethylated to form a variety of organic arsenicals differing in toxicity and environmental mobility. Trivalent methylarsenite (MAs(III)) produced in the methylation process is more toxic than inorganic arsenite (As(III)). MAs(III) also serves as a primitive antibiotic and, consequently, some environmental microorganisms have evolved mechanisms to detoxify MAs(III). However, the mechanisms of MAs(III) detoxification are not well understood. In this study, we identified an arsenic resistance ( ars ) operon consisting of three genes, arsRVK , that contribute to MAs(III) resistance in Ensifer adhaerens ST2. ArsV is annotated as an NADPH‐dependent flavin monooxygenase with unknown function. Expression of arsV in the arsenic hypersensitive Escherichia coli strain AW3110 Δars conferred resistance to MAs(III) and the ability to oxidize MAs(III) to MAs(V). In the presence of NADPH and either FAD or FMN, purified ArsV protein was able to oxidize both MAs(III) to MAs(V) and Sb(III) to Sb(V). Genes with arsV ‐like sequences are widely present in soils and environmental bacteria. Metagenomic analysis of five paddy soils showed the abundance of arsV ‐like sequences of 0.12–0.25 ppm. These results demonstrate that ArsV is a novel enzyme for the detoxification of MAs(III) and Sb(III) and the genes encoding ArsV are widely present in soil bacteria.

Research on hoop capacity of composite foundation of discarded rubber tires - Feng-Chi Wang; Jun Li; Zhen-Huan Lin; Pei-Pei Tian; Han-Yu Zhao (European Journal of Environmental and Civil Engineering, 2022)

Best Practice Data Standards for Discrete Chemical Oceanographic Observations - Li-Qing Jiang; Denis Pierrot; Rik Wanninkhof; Richard A. Feely; Bronte Tilbrook; Simone Alin; Leticia Barbero; Robert H. Byrne; Brendan R. Carter; Andrew G. Dickson; Jean-Pierre Gattuso; Dana Greeley; et al. (Frontiers in Marine Science, 2022)
Effective data management plays a key role in oceanographic research as cruise-based data, collected from different laboratories and expeditions, are commonly compiled to investigate regional to global oceanographic processes. Here we describe new and updated best practice data standards for discrete chemical oceanographic observations, specifically those dealing with column header abbreviations, quality control flags, missing value indicators, and standardized calculation of certain properties. These data standards have been developed with the goals of improving the current practices of the scientific community and promoting their international usage. These guidelines are intended to standardize data files for data sharing and submission into permanent archives. They will facilitate future quality control and synthesis efforts and lead to better data interpretation. In turn, this will promote research in ocean biogeochemistry, such as studies of carbon cycling and ocean acidification, on regional to global scales. These best practice standards are not mandatory. Agencies, institutes, universities, or research vessels can continue using different data standards if it is important for them to maintain historical consistency. However, it is hoped that they will be adopted as widely as possible to facilitate consistency and to achieve the goals stated above.

Anti-Roll Characteristics of Marine Gyrostabilizer Based on Adaptive Control and Hydrodynamic Simulation - Biao Li; Xianku Zhang; Jun Wang; Ning Chen (Journal of Marine Science and Engineering, 2022)
The gyrostabilizer produces the anti-roll effect through the precession output moment generated by a high-speed rotating flywheel. As a floating-base multi-body system composed of ship and gyrostabilizer, the recent research that has only focused on the control strategies or multi-body dynamics is obviously not comprehensive. This study presents an adaptive controller based on the variable gain control strategy for a marine gyrostabilizer installed on a port salvage tug. The variable gain control strategy controlled the flywheel precession output moment of the gyrostabilizer and thereby of the precession process, to reduce the ship roll motion effectively. Furthermore, a full-system hydrodynamic model of a gyrostabilizer-ship-wave based on three-dimensional numerical wave flume technology was innovatively established to evaluate its anti-roll performance under irregular wave conditions. The simulation results show that, for the sea state considered, the increase of spin rate of gyrostabilizer flywheel improved the anti-roll effect significantly. The average anti-roll rate of the gyrostabilizer decreased with the increase of significant wave height, wave period and wave encounter angle.

Two new threonine-containing metabolites from fungus Curvularia inaequalis strain HS-FG-257 - Shao-Yong Zhang; Jian-Song Li; Hui Zhang; Huan Qi; Rui-Jun Wang; Chou-Fei Wu; Li-Qin Zhang; An-Liang Chen; Ji-Dong Wang; Zhi-Kui Hao (Natural Product Research, 2022)

Comparative Study of Flood Coincidence Risk Estimation Methods in the Mainstream and its Tributaries - Na Li; Shenglian Guo; Feng Xiong; Jun Wang; Yuzuo Xie (Water Resources Management, 2022)

Genetic dissection of quantitative trait loci for grain size and weight by high-resolution genetic mapping in bread wheat (Triticum aestivum L.) - Tao Li; Guangbing Deng; Yan Su; Zhao Yang; Yanyan Tang; Jinhui Wang; Juanyu Zhang; Xvebing Qiu; Xi Pu; Wuyun Yang; Jun Li; Zehou Liu; et al. (Theoretical and Applied Genetics, 2022)

Characterization of Mesenchymal Stem Cells Derived from Bisphosphonate-Related Osteonecrosis of the Jaw Patients’ Gingiva - Mengyu Li; Jiajia Wang; Yejia Yu; Yuqiong Zhou; Yueqi Shi; Wenjie Zhang; Geehun Son; Jing Ge; Jun Zhao; Chi Yang; Shaoyi Wang (Stem Cell Reviews and Reports, 2022)
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a clinical condition that specifically occurs in the oral cavity, characterized by retarded wound healing in oral mucosa accelerating the exposure of bone. Moreover, the pathological mechanism remains poorly understood. Gingival mesenchymal stem cells (GMSCs) play a critical role in gingival healing and soft tissue regeneration. Although previous studies have showed that bisphosphonates (BPs) are highly toxic to healthy GMSC, there is overall lack of direct evidence demonstrating the characterization of GMSCs derived from BRONJ patients. In present study, we isolated GMSCs for the first time from the central area of BRONJ patients’ gingiva (center-BRONJ GMSCs) and the peripheral area (peri-BRONJ GMSCs), and found that they exhibited decreased proliferation, adhesion, migration capacities and underwent early apoptosis in vitro compared control GMSCs. Notably, the central and peripheral BRONJ GMSCs transplantation in a mice excisional skin model also displayed lower cell survival rate and poor healing effects than that of controls. Mechanistically, TGF-β1 signaling pathway was suppressed not only in BRONJ patients’ gingival lesions but also in BRONJ GMSCs transplantation animal model. The results above suggested that under the microenvironment of BRONJ patients, the dysfunction of GMSCs and the suppressed TGF-β1 signaling pathway may be the vital factors in impaired gingival healing, thus contributing to persistent exposure of underlying bone and development of BRONJ. This study provides new insights into the prevention for BRONJ by improving the functions of GMSCs and upregulating TGF-β1 in accelerating gingival wound healing. Graphical Abstract Schematic illustration of the dysfunction of BRONJ GMSCs in vitro and BRONJ GMSCs transplantation in a mice skin model delaying cutaneous wound healing mainly via suppressing TGF-β1 signaling pathway.

Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma - Cheng Wang; Mingtao Huang; Congcong Chen; Yuancheng Li; Na Qin; Zijian Ma; Jingyi Fan; Linnan Gong; Hui Zeng; Liu Yang; Xianfeng Xu; Jun Zhou; et al. (Science China Life Sciences, 2022)

Fruit and vegetable consumption, cardiovascular disease, and all-cause mortality in China - Jun Wang; Fangchao Liu; Jianxin Li; Keyong Huang; Xueli Yang; Jichun Chen; Xiaoqing Liu; Jie Cao; Shufeng Chen; Chong Shen; Ling Yu; Fanghong Lu; et al. (Science China Life Sciences, 2022)

Flood vulnerability assessment using the triangular fuzzy number-based analytic hierarchy process and support vector machine model for the Belt and Road region - Yu Duan; Junnan Xiong; Weiming Cheng; Nan Wang; Yi Li; Yufeng He; Jun Liu; Wen He; Gang Yang (Natural Hazards, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

Temperature might increase the hospital admission risk for rheumatoid arthritis patients in Anqing, China: a time-series study - Li-Juan Huang; Jun-Jing Zha; Nv-Wei Cao; Hao-Yue Zhou; Xiu-Jie Chu; Hua Wang; Xian-Bao Li; Bao-Zhu Li (International Journal of Biometeorology, 2022)

Seasonal and spatial variations in the phytoplankton community and their correlation with environmental factors in the Jinjiang River Estuary in Quanzhou, China - Yanmei Wu; Peiyong Guo; Haitao Su; Yuxuan Zhang; Jun Deng; Meixian Wang; Yinshi Sun; Yanqi Li; Xiaoyan Zhang (Environmental Monitoring and Assessment, 2022)

Paracoccus shandongensis sp. nov., Isolated from Activated Sludge - Xiao-Fan Gong; Fang Wang; Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Zong-Jun Du; Qiang Li (Current Microbiology, 2022)

Mitochondrial Ferritin Deficiency Promotes Osteoblastic Ferroptosis Via Mitophagy in Type 2 Diabetic Osteoporosis - XinDong Wang; HongDong Ma; Jun Sun; TianYu Zheng; Peng Zhao; HaiTian Li; MaoWei Yang (Biological Trace Element Research, 2022)