Hyphomonas sediminis sp. nov., isolated from marine sediment - Lu Wang; Wei He; Zeng-Yu Gao; Dao-Feng Zhang; Jian-Ke Huang; Chuang Liu; Wen-Jun Li; Ai Hua Zhang (Antonie van Leeuwenhoek, 2022)

Ancylostoma ceylanicum Infection in a Miniature Schnauzer Dog Breed - Xu-Hui Lin; Hai-Ming Cai; Zhuan-Qiang Yan; Shen-Quan Liao; Min-Na Lv; Cai-Yan Wu; Juan Li; Jun-Jing Hu; Wen-Wan Xiao; Jian-Fei Zhang; Nan-Shan Qi; Ming-Fei Sun (Acta Parasitologica, 2022)

Potential millennial‐scale avian declines by humans in southern China - Feng Dong; Qiang Zhang; Yi‐Lin Chen; Fu‐Min Lei; Shou‐Hsien Li; Fei Wu; Xiao‐Jun Yang (Global Change Biology, 2022)
Mounting observational records demonstrate human‐caused faunal decline in recent decades, while accumulating archaeological evidence suggests an early biodiversity impact of human activities during the Holocene. A fundamental question arises concerning whether modern wildlife population declines began during early human disturbance. Here, we performed a population genomic analysis of six common forest birds in East Asia to address this question. For five of them, demographic history inference based on 25–33 genomes of each species revealed dramatic population declines by 4‐ to 48‐fold over millennia (e.g. 2000–5000 thousand years ago). Nevertheless, summary statistics detected nonsignificant correlations between these population size trajectories and Holocene temperature variations, and ecological niche models explicitly predicted extensive range persistence during the Holocene, implying limited demographic consequence of Holocene climate change. Further analyses suggest high negative correlations between the reconstructed population declines and human disturbance intensities and indicate a potential driver of human activities. These findings provide a deep‐time and large‐scale insight into the recently recognized avifaunal decline and support an early origin hypothesis of human effects on biodiversity. Overall, our study sheds light on the current biodiversity crisis in the context of long‐term human–environment interactions and offers a multi‐evidential framework for quantitatively assessing the ecological consequences of human disturbance.

Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors - Li-Ping Shen; Wei Li; Ling-Zhu Pei; Jun Yin; Shu-Tao Xie; Hong-Zhao Li; Chao Yan; Jian-Jun Wang; Qipeng Zhang; Xiao-Yang Zhang; Jing-Ning Zhu (The Cerebellum, 2022)

Quantitative susceptibility atlas construction in Montreal Neurological Institute space: towards histological-consistent iron-rich deep brain nucleus subregion identification - Chenyu He; Xiaojun Guan; Weimin Zhang; Jun Li; Chunlei Liu; Hongjiang Wei; Xiaojun Xu; Yuyao Zhang (Brain Structure and Function, 2022)

Exploring the Spatial and Temporal Distribution of Frigate Tuna (Auxis thazard) Habitat in the South China Sea in Spring and Summer during 2015–2019 Using Fishery and Remote Sensing Data - Xingxing Zhou; Zuozhi Chen; Pengli Xiong; Yancong Cai; Jie Li; Peng Zhang; Jun Zhang; Miao Li; Jiangtao Fan (Fishes, 2022)
Frigate tuna Auxis thazard fishery is considered a potential marine resource in the open South China Sea (SCS). However, little is known about the spatial and temporal distribution of its habitat, and how this may respond to environmental changes. Using fish survey and remote sensing data from 2015–2019, we applied generalized additive models to identify relationships between environmental factors and the distribution of A. thazard in the SCS. To examine seasonal patterns in the habitat of A. thazard in the SCS, we generated a habitat suitability index model using environmental factors screened by generalized additive models. Results showed that A. thazard migrates from south to north in the SCS, and its suitable habitat is patchily distributed. Significant environmental factors affecting the habitat of A. thazard distribution were different in different seasons; we demonstrated A. thazard to be sensitive to Chl-a in spring (optimum 0.155, optimal range ~0.1252–0.1840), and in summer to be sensitive to SST (optimum 30.405, optimal range ~29.789–31.021) and SSH (optimum 0.741, optimal range ~0.618–0.864). Suitable habitat in spring occurs mainly in northeastern areas, while in summer it occurs mainly around the southeastern Nansha Islands. Compared with that in spring, the area of suitable habitat increases in summer, as does the habitat suitability index of the entire sea area. These results improve our understanding of environmental factors that affect the distribution of A. thazard habitat in the SCS, and provide a scientific basis for the development and management of A. thazard resources.

Spatio-temporal distribution and mechanism of Cenozoic magmatism in the South China Sea and adjacent areas: Insight from seismic, geochemical and geochronological data - Song Zhu; Yongjian Yao; Xuejie Li; Hongfang Gao; Jiangyong Zhang; Ziying Xu; Jun Wang (International Geology Review, 2022)

Genetic basis underlying tiller angle in rice (Oryza sativa L.) by genome-wide association study - Shaoxing Bai; Jun Hong; Su Su; Zhikang Li; Wensheng Wang; Jianxin Shi; Wanqi Liang; Dabing Zhang (Plant Cell Reports, 2022)

Heroin Addiction Induces Axonal Transport Dysfunction in the Brain Detected by In Vivo MRI - Yueyuan Luo; Chengde Liao; Long Chen; Yongjin Zhang; Shasha Bao; Ailin Deng; Tengfei Ke; Qinqing Li; Jun Yang (Neurotoxicity Research, 2022)

Microglia-induced autophagic death of neurons via IL-6/STAT3/miR-30d signaling following hypoxia/ischemia - Jun Shu; Xu-Hao Fang; Ya-Jian Li; Yao Deng; Wen-Shi Wei; Li Zhang (Molecular Biology Reports, 2022)

Updated taxonomy of Chinese Clavaria subg. Syncoryne (Clavariaceae, Agaricales): description of two new species and one newly recorded species - Jun Yan; Gui-Wu Li; Wen-Hao Liu; Zuo-Hong Chen; Ping Zhang (Mycological Progress, 2022)

Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport - Jin-Ming Zhang; Ming-Jie Chen; Jiong-Hui He; Ya-Ping Li; Zhi-Cai Li; Zi-Jing Ye; Yong-Hui Bao; Bing-Jun Huang; Wen-Jie Zhang; Ping Kwan; Yu-Ling Mao; Jing-da Qiao (Journal of Molecular Neuroscience, 2022)

Integrated analysis of the miRNA and mRNA expression profiles in Leiocassis longirostris at gonadal maturation - Han Zhao; Lu Zhang; Qiang Li; Zhongmeng Zhao; Yuanliang Duan; Zhipeng Huang; Hongyu Ke; Chao Liu; Huadong Li; Lu Liu; Jun Du; Zhen Wei; et al. (Functional & Integrative Genomics, 2022)

Identification and expression of potential olfactory-related genes related to Niemann–Pick C2 protein and ionotropic receptors in Haemaphysalis longicornis - Yingying Cui; Jungang Wang; Qiyong Liu; Dongmei Li; Wen Zhang; Xiaobo Liu; Jun Wang; Xiuping Song; Feng Yao; Haixia Wu; Ning Zhao (Experimental and Applied Acarology, 2022)

Microfluidic preparation of a novel phoxim nanoemulsion pesticide against Spodoptera litura - Zong-Nan Li; Yu-Xuan Zhang; Zhi-Ang Zhang; Lian-Han Pan; Ping Li; Yan Xu; Sheng Sheng; Fu-An Wu; Jun Wang (Environmental Science and Pollution Research, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Effects of Cinnamomum camphora Leaves Extracts-Flocculants Composite Algaecide on Microcystis aeruginosa Growth and Microcystins Release - Han-yun Li; Yin-dong Ye; Qi-jun Zhang; Cun-hao Du; Hui-ming Li; Li Yin (Bulletin of Environmental Contamination and Toxicology, 2022)

Alterations to cognitive abilities and functional networks in rats post broad-band intense noise exposure - Xiao-Min Xu; Yu-Qun Zhang; Feng-Chao Zang; Chun-Qiang Lu; Li-Jie Liu; Jian Wang; Richard Salvi; Yu-Chen Chen; Gao-Jun Teng (Brain Imaging and Behavior, 2022)

Fertility conversion between cytoplasmic maintainer lines and restorer lines through molecular marker-assisted selection in pepper (Capsicum annuum L.) - Fu-Sen Ren; Hai-Feng Yang; Yu-Shun Jiao; Rui-Ping Zhang; Zhi-Wei Guo; He-Juan Liu; Qiang Sun; Xi-Jun Li; Xiu-Fang Tan; Bei Zhang; Jun-Qi Zhen; Yan-Qi Dong (Biologia, 2022)

Effects of climate change on major elements of the hydrological cycle in Aksu River basin, northwest China - Peng Yang; Wenyu Wang; Jun Xia; Yaning Chen; Chesheng Zhan; Shengqing Zhang; Cai Wei; Xiangang Luo; Jiang Li (International Journal of Climatology, 2022)
Water resources systems in arid regions are sensitive to climate change, which critically impacts the water cycle. In this study, we applied historical hydrometeorological data, CMIP5 data, and a large‐scale hydrological model (Community Land Model–Distributed Time‐Variant Gain Model [CLM–DTVGM]) to study the impact of climate change on the hydrological cycle (i.e., runoff, actual evapotranspiration (ET a ), and terrestrial water storage [TWS]) under different scenarios at the Aksu River basin (ARB) located in the arid region of northwest China. The primary findings of this study: (a) As the determination coefficient ( R 2 ) and Nash–Sutcliffe efficiency coefficient (NSE) reached desirable levels ( R 2 ≥ 0.583, NSE ≥ 0.371, and root‐mean‐square error ≤ 155.727), the CLM–DTVGM achieved a better simulation of runoff in the ARB; under climate change, the runoff depth in the irrigation area became shallower and followed a decreasing trend, with a minimum depth of 0.5 mm and a significant decreasing trend of −8 mm·a −1 . (b) Along with changes in the precipitation and temperature of the baseline period (i.e., 1980–2010), runoff, ET a , and TWS were predicted to change significantly in future scenarios. (c) Climate change significantly impacted the historical runoff from the Shaliguilanke and Xiehela hydrological stations, with correlation coefficients larger than 0.9; however, the runoff from the Alaer hydrological station was not affected. However, runoff, ET a , and TWS in the ARB were very closely correlated with climate change in the future scenarios, with correlation coefficients exceeding 0.9. Related research in the future would be important for guiding the sustainable development of the ARB.

Improving protected area effectiveness through consideration of different human‐pressure baselines - Chun‐Ting Feng; Ming Cao; Fang‐Zheng Liu; Yue Zhou; Jin‐Hong Du; Li‐Bo Zhang; Wen‐Jie Huang; Jian‐Wu Luo; Jun‐Sheng Li; Wei Wang (Conservation Biology, 2022)
Previous assessments of the effectiveness of protected areas (PAs) focused primarily on changes in human pressure over time and did not consider the different human‐pressure baselines of PAs, thereby potentially over‐ or underestimating PA effectiveness. We developed a framework that considers both human‐pressure baseline and change in human pressure over time and assessed the effectiveness of 338 PAs in China from 2010 to 2020. The initial state of human pressure on PAs was taken as the baseline, and changes in human pressure index (HPI) were further analyzed under different baselines. We used the random forest models to identify the management measures that most improved effectiveness in resisting human pressure for the PAs with different baselines. Finally, the relationships between the changes in the HPI and the changes in natural ecosystems in PAs were analyzed with different baselines. Of PAs with low HPI baselines, medium HPI baselines, and high HPI baselines, 76.92% ( n =150), 11.11% ( n =12), and 22.86% ( n =8) , respectively, showed positive effects in resisting human pressure. Overall, ignoring human‐pressure baselines somewhat underestimated the positive effects of PAs, especially for those with low initial human pressure. For PAs with different initial human pressures, different management measures should be taken to improve effectiveness and reduce threats to natural ecosystems. We believe our framework is useful for assessing the effectiveness of PAs globally, and we recommend it be included in the Convention on Biological Diversity Post‐2020 Strategy.

Transition between Mycobacterium tuberculosis and nontuberculous mycobacteria in recurrent “tuberculosis” patients - Qing Li; Haoran Li; Jun An; Xuxia Zhang; Wei Wang; Yufeng Wang; Zhongtan Xue; Shanshan Li; Yu Pang (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Revealing Selection in Breeding and Genetic Characteristics of Economically Important Traits of New Species of Apostichopus Japonicas Based on Genome Resequencing and GWAS Analysis - Chao Guo; Yuanxin Li; Jiahui Xie; Lingshu Han; Youquan Wang; Xianglei Zhang; YangLei Wu; Jian Song; Yaqing Chang; Jun Ding (Frontiers in Marine Science, 2022)
Apostichopus japonicas is an economically important species with high nutritional value. However, our knowledge of its genetic diversity and the genetic changes that occurred during its domestication or trait selection is quite limited. In this study, the whole genomes of 254 A . japonicas samples were resequenced. Analyses of the population genetic structure revealed that the genetic diversity of A. japonicas in the north of China is generally high, there was no difference in the population structure among the six cultured populations, and they were divided into two subpopulations together with AY-1 (new species). The results also showed that the genetic diversity of the AY-1 population was relatively low, the degree of linkage of alleles was high, and this population had been subjected to more positive selection. Based on Tajima’s D, F ST analysis, and ROD analysis, the selected intervals and genes of the AY-1 population were identified, with some of the candidate intervals being related to an economically important trait and breeding target, namely, the number of parapodia. Gene Ontology analysis of the candidate genes revealed that the two subpopulations differed in their immune function, protein synthesis, decomposition, and transport, among others. Using GWAS, we identified 39 candidate genes for four economically important traits of A. japonicas , and we verified that those genes contained non-synonymous SNPs. Through this verification, BSL78_00022 and BSL78_00023 were found to be key genes for the number of parapodia in A. japonicas . Of these two genes, BSL78_00022 encodes a protein related to cell differentiation and proliferation, so it was assumed that three non-synonymous substitutions (Ser-Phe, Glu-Asp, and Ala-Val) in this gene are related to the changes in the number of parapodia. Meanwhile, the pleiotropic gene BSL78_04631, which is related to body weight and body wall weight, and promotes protein synthesis and cell growth, has a non-synonymous substitution (IlE-Val), which is assumed to be the reason for the difference in body weight and body wall weight of A. japonicas . These results provide a new perspective for explaining the genetic structure characteristics of A. japonicas and analyzing the selection and economically important traits in the breeding of new species.

Effects of 3,6-Dibromocarbazole on Soil Health—Based on Soil Enzymes and the Biolog-ECO Test - Zhongkun Du; Ji Zhang; Chao Cheng; Baihui Shi; Lusheng Zhu; Jun Wang; Jinhua Wang; Bing Li (Water, Air, & Soil Pollution, 2022)

Experimental Investigation of Decoupled Charge Effect on Rock Fragmentation by Blasting - Li Yuan Chi; Cheng Wang; Zong-Xian Zhang; Xuan Xu; Jun Yang (Rock Mechanics and Rock Engineering, 2022)

Intensified rainfall in the wet season alters the microbial contribution to soil carbon storage - Jinge Zhou; Jingfan Zhang; Hans Lambers; Jingtao Wu; Guoming Qin; Yingwen Li; Yongxing Li; Zhian Li; Jun Wang; Faming Wang (Plant and Soil, 2022)

Correction to: Matrine Treatment Blocks NogoA-Induced Neural Inhibitory Signaling Pathway in Ongoing Experimental Autoimmune Encephalomyelitis - Quan-Cheng Kan; Hui-Jun Zhang; Yuan Zhang; Xing Li; Yu-Ming Xu; Rodolfo Thome; Ming-Liang Zhang; Nan Liu; Yao-Juan Chu; Guang-Xian Zhang; Lin Zhu (Molecular Neurobiology, 2022)

Co-regulation of circadian clock genes and microRNAs in bone metabolism - Tingting Li; Shihua Zhang; Yuxuan Yang; Lingli Zhang; Yu Yuan; Jun Zou (Journal of Zhejiang University-SCIENCE B, 2022)

Pharmacokinetics of benapenem for injection in subjects with mild to moderate renal impairment - Haijing Yang; Min Zhang; Yuancheng Chen; Hong Ren; Hong Zhang; Chen Yu; Jianda Lu; Li You; Jicheng Yu; Hong Liang; Cuilan Xiao; Zishuang He; et al. (European Journal of Clinical Pharmacology, 2022)

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

Transition metal ions-modified birnessite toward highly efficiency photocatalytic formaldehyde oxidation under visible light irradiation - Changye Mang; Guanghui Li; Mingjun Rao; Xin Zhang; Jun Luo; Tao Jiang (Environmental Science and Pollution Research, 2022)

Does green credit policy promote the green innovation efficiency of heavy polluting industries?—empirical evidence from China’s industries - Su Li; Wei Zhang; Jun Zhao (Environmental Science and Pollution Research, 2022)

Study on Preparation and Properties of Red Mud Magnesium Oxysulfate Cement Foamed Concrete - Wei-Ying Li; Jun-Bo Zhou; Zhi-Yuan Zhang; Xin-Xiong Zhu (Bulletin of Environmental Contamination and Toxicology, 2022)

Total, bioavailable and free 25-hydroxyvitamin D are associated with the prognosis of patients with non-small cell lung cancer - Si-Min Peng; Na Yu; Jun Che; Jia-Ying Xu; Guo-Chong Chen; Da-Peng Li; Yu-Song Zhang; Li-Qiang Qin (Cancer Causes & Control, 2022)

Testing the transfer functions for the Geonor T-200B and Chinese standard precipitation gauge in the central Qinghai—Tibet Plateau - Le-le Zhang; Li-ming Gao; Ji Chen; Lin Zhao; Ke-long Chen; Jing-yi Zhao; Guo-jun Liu; Ting-xi Song; Yan-kun Li (Journal of Mountain Science, 2022)

ArsZ from Ensifer adhaerens ST2 is a novel methylarsenite oxidase - Jun Zhang; Yan‐Ning Li; Jian Chen; Yu Yan; Barry P. Rosen; Fang‐Jie Zhao (Environmental Microbiology, 2022)
Summary Trivalent methylarsenite [MAs(III)] produced by biomethylation is more toxic than inorganic arsenite [As(III)]. Hence, MAs(III) has been proposed to be a primordial antibiotic. Other bacteria evolved mechanisms to detoxify MAs(III). In this study, the molecular mechanisms of MAs(III) resistance of Ensifer adhaerens ST2 were investigated. In the chromosome of E. adhaerens ST2 is a gene encoding a protein of unknown function. Here, we show that this gene, designated arsZ , encodes a novel MAs(III) oxidase that confers resistance by oxidizing highly toxic MAs(III) to relatively nontoxic MAs(V). Two other genes, arsRK , are adjacent to arsZ but are divergently encoded in the opposite direction. Heterologous expression of arsZ in Escherichia coli confers resistance to MAs(III) but not to As(III). Purified ArsZ catalyses thioredoxin‐ and NAPD + ‐dependent oxidation of MAs(III). Mutational analysis of ArsZ suggests that Cys59 and Cys123 are involved in the oxidation of MAs(III). Expression of arsZ , arsR and arsK genes is induced by MAs(III) and As(III) and is likely controlled by the ArsR transcriptional repressor. These results demonstrate that ArsZ is a novel MAs(III) oxidase that contributes to E. adhaerens tolerance to environmental organoarsenicals. The arsZRK operon is widely present in bacteria within the Rhizobiaceae family.

Sea Urchins in Acute High Temperature and Low Oxygen Environments: The Regulatory Role of microRNAs in Response to Environmental Stress - Lingshu Han; Yanglei Wu; Pengfei Hao; Beichen Ding; Yuanxin Li; Wenpei Wang; Xianglei Zhang; Chuang Gao; Heng Wang; Luo Wang; Weijie Zhang; Yaqing Chang; et al. (Frontiers in Marine Science, 2022)
Strongylocentrotus intermedius is an economically valuable sea urchin species in China. However, its growth and survival are severely constrained by ocean warming and the hypoxia that often accompanies high water temperatures. MicroRNAs (miRNAs) are important regulators of gene expression in response to environmental change. In this study, high-throughput RNA sequencing was used to investigate changes in miRNA expression in S. intermedius under heat (25°C), hypoxia (2 mg/L O 2 ), and combined heat and hypoxia stresses. Twelve small RNAs libraries were constructed and 17, 14, and 23 differentially expressed miRNAs (DEMs) were identified in the heat, hypoxia, and combined stress groups ( P <0.05), respectively. Gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway functional analyses of putative target genes of the DEMs suggested that these miRNAs were important in basal metabolism, apoptosis, oxidative stress, and immune-related pathways. By co-analysis with published transcriptome data, key DEMs (miR-193, miR-184, miR-133, miR-125, miR-2008) and their key target genes ( EGF3 , ABCB4 , CYCL , PAN2 , CALN ) were identified. Quantitative real-time PCR analysis of the expression of 10 DEMs and their key target genes confirmed the RNA sequencing results. These results provide information on gene expression regulation of the molecular mechanisms underlying the response of S. intermedius to multi-cause environmental stresses.

Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells - Zhangyu Yao; Xiang Li; Jun Gao; Yutao Wang; Linmei Xiao; Xinxia Chang; Fangzhou Liu; Zhenqing Feng; Xiao Zhang (Human Cell, 2022)

Diversity and Structure of Demersal Fish Community Over the Northern Slope in the South China Sea - Jun Zhang; Kui Zhang; Yan-e Jiang; Yuan-jie Li; Jiang-tao Fan; Wen-ming Yu; Zuo-zhi Chen (Frontiers in Marine Science, 2022)
Three bottom trawl surveys over the northern continental slope in the South China Sea (18°50′–20°40′N, 112°50′–115°10′E) were carried out, in June 2015, March 2017 and September 2018, to investigate species composition, biodiversity and community structure of demersal fish. Surveys in 2015, 2017 and 2018 captured 97 fish species (representing 77 genera, 52 families, 26 orders), 108 fish species (representing 84 genera, 61 families, 19 orders) and 126 fish species (representing 105 genera, 74 families, 25 orders), respectively. Three surveys captured a total of 252 fish species, representing 164 genera, 97 families, 30 orders. Perciformes dominated. Species richness in station linking shallow continental shelf with deep slope was the lowest among stations. In three surveys, 16 species occurred in the catches of three surveys, accounting for 6.35% of all species. Species replacement rate between stations showed a significant linear relationship with the depth difference and latitude difference. Margalef’s species richness index ( D ), Shannon–Weiner diversity index ( H’ ) and Pielou’s evenness index ( J’ ) among stations ranged 2.65–6.74, 1.02–4.15 and 0.28–1.14, respectively. Differences of D , H ’ and J ’ were insignificant among seasons. There were significant positive linear relations between H’ and J’ and latitude. D , H’ and J’ decreased with increasing sampling depth, however the relations were not significant. Based on multivariate statistical analysis, fish community at species level was divided into five groups with average dissimilarities of 95.69%–99.96%. In terms of genus and family, average dissimilarities among groups were more than 88.11% and 82.69%. There were significant differences in species composition between depths, but no significant differences between seasons and temperatures, as well as in genus and family composition.

Spatiotemporal variation of precipitation on a global scale from 1960 to 2016 in a new normalized daily precipitation dataset - Jun Liu; Dongyou Wu; Yue Li; Hongli Ren; Yongtao Zhao; Xiaoyu Sun; Haitao Zhang; Mingxia Ji (International Journal of Climatology, 2022)
Increases in total and extreme precipitation have been investigated worldwide using limited spatiotemporal data based on surface observations and satellite remote sensing during recent decades. However, it remains unclear whether rain gauge daily precipitation records also show a significant increase in global precipitation. In this study, we first apply the transformed version of the penalized maximum F test (“transPMFred”) to homogenize daily precipitation (P) records from 10,629 stations around the world during 1960–2016 from a dataset (GHCN‐CMA) that combines the daily precipitation data from the Global Historical Climatology Network (GHCN‐Daily) dataset and the China Meteorological Administration (CMA), and then utilize the homogenized data to study the frequency of daily precipitation on a global scale. The results indicate that precipitation frequency exhibited significant increasing trends from 1960 to 2016 across most of the globe, except for East Asia. Moreover, the variability of global precipitation frequency was more pronounced in wet regions than dry regions, especially in North America, Europe and East Asia based multiple daily precipitation datasets. The regional average frequency for moderate (30th 90th percentile) precipitation increased in North America and Europe. Changes in precipitation frequency decreased for light (P ≤ 30th percentile) and moderate precipitation but increased for heavy and very heavy precipitation, which mainly occurs in dry regions of Australia. Moreover, precipitation frequency in wet and dry regions of East Asia showed opposite trends, with a decrease in wet regions and an increase in dry regions.

New bioactive α-pyrone from wild mushroom Paxillus involutus - Jian-Hua Lv; Lan Yao; Chao Duan; Zhuang Li; Jun Zhang; Chang-Tian Li; Yu Li (Natural Product Research, 2022)

Improved and Flexible HDR Editing by Targeting Introns in iPSCs - Juan Fu; Ya-Wen Fu; Juan-Juan Zhao; Zhi-Xue Yang; Si-Ang Li; Guo-Hua Li; Zi-Jun Quan; Feng Zhang; Jian-Ping Zhang; Xiao-Bing Zhang; Chang-Kai Sun (Stem Cell Reviews and Reports, 2022)
Highly efficient gene knockout (KO) editing of CRISPR–Cas9 has been achieved in iPSCs, whereas homology-directed repair (HDR)-mediated precise gene knock-in (KI) and high-level expression are still bottlenecks for the clinical applications of iPSCs. Here, we developed a novel editing strategy that targets introns. By targeting the intron before the stop codon, this approach tolerates reading frameshift mutations caused by nonhomologous end-joining (NHEJ)-mediated indels, thereby maintaining gene integrity without damaging the non-HDR-edited allele. Furthermore, to increase the flexibility and screen for the best intron-targeting sgRNA, we designed an HDR donor with an artificial intron in place of the endogenous intron. The presence of artificial introns, particularly an intron that carries an enhancer element, significantly increased the reporter expression levels in iPSCs compared to the intron-deleted control. In addition, a combination of the small molecules M3814 and trichostatin A (TSA) significantly improves HDR efficiency by inhibiting NHEJ. These results should find applications in gene therapy and basic research, such as creating reporter cell lines.

Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities - Lu Luo; Jun Yang; Cheng Wang; Jie Wu; Yafang Li; Xu Zhang; Hui Li; Hui Zhang; Yumei Zhou; Aiping Lu; Shilin Chen (Science China Life Sciences, 2022)

Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat - Dong Peng; Han-Zi Qiao; Hong-Yu Tan; Yi-Xue Wang; Dan Luo; Li-Jun Qiao; Ye-Feng Cai; Shi-Jie Zhang; Qi Wang; Li Guan (Metabolic Brain Disease, 2022)

Isolation and identification of a mesenchymal stem/stromal cell-like population from pediatric urethral tissue - Shilin Zhang; Jierong Li; Chunjing Li; XuminXie; Jun He; Fengsheng Ling; Guoqing Liu (In Vitro Cellular & Developmental Biology - Animal, 2022)

Experimental study on coal dust wettability strengthened by surface active ionic liquids - Weiqing Zhang; Qiang Hu; Shuguang Jiang; Li Wang; Jun Chai; Jingxin Mei (Environmental Science and Pollution Research, 2022)

Impacts of nanoplastics on life-history traits of marine rotifer (Brachionus plicatilis) are recovered after being transferred to clean seawater - Dong Wang; Shaoguo Ru; Wei Zhang; Zhenzhong Zhang; Yuejiao Li; Lingchao Zhao; Lianxu Li; Jun Wang (Environmental Science and Pollution Research, 2022)

Comment on “Relationship of Circulating Copper Level with Gestational Diabetes Mellitus: a Meta-analysis and Systemic Review” - Shu-ping Li; Xiao-ping Zhang; Xin-hong Cui; Li-juan Zhao; Yan-jun Rong (Biological Trace Element Research, 2022)

Therapeutic Effects of Sodium Para-Aminosalicylic Acid on Cognitive Deficits and Activated ERK1/2-p90RSK/NF-κB Inflammatory Pathway in Pb-Exposed Rats - Li-li Lu; Yu-wen Zhang; Zhao-cong Li; Yuan-yuan Fang; Lei-lei Wang; Yue-song Zhao; Shao-jun Li; Shi-yan Ou; Michael Aschner; Yue-ming Jiang (Biological Trace Element Research, 2022)

Hydrogeochemical Processes of Carboniferous Limestone Groundwater in the Yangzhuang Coal Mine, Huaibei Coalfield, China - Jie Zhang; Luwang Chen; Xiaowei Hou; Xingxing Ren; Jun Li; Yifei Chen (Mine Water and the Environment, 2022)

Failure mechanisms and risk mitigation of check dams on the Chinese Loess Plateau: A case study at the Gutun Gully - Rui-jun Jiang; Mao-sheng Zhang; Li Feng; Ping-ping Sun (Journal of Mountain Science, 2022)

Alternate freezing and thawing enhanced the sediment and nutrient runoff loss in the restored soil of the alpine mining area - Fa-Yong Li; Ren-jie Luo; Yong-jun You; Xue-fei Hu; Xiao-yan Qian; Peng-yan Zhang; Shan Wang; Guo-yu Li; Mohamed Eltohamy Kamel (Journal of Mountain Science, 2022)

Risk factors of herpes simplex virus reactivation after surgery for primary trigeminal neuralgia - Xueke Zhen; Xiaoli Xu; Xu Shao; Hong Tian; Jun Xu; Bin Zhu; Ying Zuo; Li Zhang; Yanbing Yu (Journal of NeuroVirology, 2022)

The Impact of Urban Expansion on Plant Diversity Change in Karst Regions of Southwest China - Shengtian Yang; Chaojun Li; Hezhen Lou; Ya Luo; Pengfei Wang; Jun Zhang; Xi Li; Xijin Wu (Chinese Geographical Science, 2022)

The Role of Long Non-coding RNA, Nuclear Enriched Abundant Transcript 1 (NEAT1) in Cancer and Other Pathologies - Miao Zhang; Jianmin Guo; Lifei Liu; Mei Huang; Yuexuan Li; Samuel Bennett; JiaKe Xu; Jun Zou (Biochemical Genetics, 2022)

Three-dimensional modeling and porosity calculation of coal rock pore structure - Qiong Li; Zheng Chen; Lin Yue; Yu Zhang; Jian-Jun He; Yong Li (Applied Geophysics, 2022)

In vitro Scolicidal Efficacy of 5-Fluorouracil and Radiation Against Protoscoleces of Echinococcus granulosus Sensu Lato - Pengfei Lu; Jun Li; Rui Mao; Hongzhi Qi; Liping Yang; Qin Zhou; Mengxiao Tian; Wenbao Zhang; Yongxing Bao (Acta Parasitologica, 2022)

Distribution of phytoplankton in the East China Sea and the southern Yellow Sea in spring in relation to environmental variables and dimethylsulfide compounds - Jiawei Zhang; Yanghang Chen; Xueyan Ren; Vishal Patil; Lin Sun; Xuesong Li; Junrong Liang; Jun Zhang; Yahui Gao; Changping Chen (Acta Oceanologica Sinica, 2022)

Natural component plumbagin as a potential antibacterial agent against Streptococcus agalactiae infection - Ai‐Guo Huang; Lin‐Jun Su; Wei‐Hao He; Fa‐Li Zhang; Chao‐Shuai Wei; Ying‐Hui Wang (Journal of Fish Diseases, 2022)
Streptococcus agalactiae , also known as Group B Streptococcus (GBS), can infect humans, terrestrial animals and fish. The emergence of bacterial resistance of S. agalactiae to antibiotics leads to an urgent need of exploration of new antimicrobial agents. In the study, the antibacterial activity of natural component plumbagin (PLB) against S. agalactiae was investigated in vitro and in vivo. The results showed that the minimal inhibitory concentration (MIC) of PLB against S. agalactiae was 8 mg/L. The growth curve assay revealed that PLB could inhibit the growth of S. agalactiae . In addition, the time‐killing curve showed that S. agalactiae was killed almost completely by 2‐fold MIC of PLB within 12 h. Transmission electron microscopy results showed obvious severe morphological destruction and abnormal cells of S. agalactiae after treated with PLB. The pathogenicity of S. agalactiae to zebrafish was significantly decreased after preincubation with PLB for 2 h in vitro, further indicating the bactericidal activity of PLB. Interestingly, PLB could kill S. agalactiae without inducing resistance development. Furthermore, pretreatment and post‐treatment assays suggested that PLB also exhibited the antibacterial activity against S. agalactiae infection in vivo by effectively reducing the bacterial load and improving the survival rate of S. agalactiae ‐infected zebrafish. In summary, PLB had potent antibacterial activity against S. agalactiae in vitro and in vivo, and it could be an excellent antimicrobial candidate to prevent and control S. agalactiae infection.

Functional diversity loss and change in nocturnal behavior of mammals under anthropogenic disturbance - Xueyou Li; Wenqiang Hu; William V. Bleisch; Quan Li; Hongjiao Wang; Wen Lu; Jun Sun; Fuyou Zhang; Bu Ti; Xuelong Jiang (Conservation Biology, 2022)
In the Anthropocene, understanding the impacts of anthropogenic influence on biodiversity and behavior of vulnerable wildlife communities is increasingly relevant to effective conservation. However, comparative studies aimed at disentangling the concurrent effect of different types of human disturbance on multifaceted biodiversity and on activity patterns of mammals are surprisingly rare. We applied a multiregion community model to separately estimate the effects of cumulative human modification (e.g., settlement, agriculture, and transportation) and human presence (aggregated presence of dogs, people, and livestock) on species richness and functional composition of medium‐ and large‐bodied mammals based on camera trap data collected across 45 subtropical montane forests. We divided the detected mammal species into three trophic guilds–carnivores, herbivores, and omnivores–and assessed the nocturnal shifts of each guild in response to anthropogenic activities. Overall, species richness tended to increase ( β coefficient = 0.954) as human modification increased but richness decreased as human presence increased ( β = –1.054). Human modification was associated with significantly lower functional diversity (mean nearest taxon distance [MNTD], β = –0.134; standardized effect sizes of MNTD, β = –0.397), community average body mass ( β = –0.240), and proportion of carnivores ( β = –0.580). Human presence was associated with a strongly reduced proportion of herbivores ( β = –0.522), whereas proportion of omnivores significantly increased as human presence ( β = 0.378) and habitat modification ( β = 0.419) increased. In terms of activity patterns, omnivores ( β = 12.103) and carnivores ( β = 9.368) became more nocturnal in response to human modification. Our results suggest that human modification and human presence have differing effects on mammals and demonstrate that anthropogenic disturbances can lead to drastic loss of functional diversity and result in a shift to nocturnal behavior of mammals. Conservation planning should consider concurrent effects of different types of human disturbance on species richness, functional diversity, and behavior of wildlife communities.

Massive Heat Shock Protein 70 Genes Expansion and Transcriptional Signatures Uncover Hard Clam Adaptations to Heat and Hypoxia - Zhi Hu; Hao Song; Jie Feng; Cong Zhou; Mei-Jie Yang; Pu Shi; Zheng-Lin Yu; Yong-Ren Li; Yong-Jun Guo; Hai-Zhou Li; Tao Zhang (Frontiers in Marine Science, 2022)
Heat shock protein 70 (HSP70) members participate in a wide range of housekeeping and stress-related activities in eukaryotic cells. In marine ecosystems, bivalves encounter abiotic stresses, including high temperatures and low dissolved oxygen. Here, 133 MmHSP70 genes were identified through combined methods including Blastp, HMM and manual filtration, based on the whole Mercenaria mercenaria genome. The MmHSP70 genes were unevenly distributed, and 41 genes (33.08%) were located on Chr 7. Phylogenetic analyses indicated that the MmHSP70 gene family mainly consisted of two clusters and the Hspa12 subfamily underwent lineage-specific expansion. A high-density collinear gene block was observed between M. mercenaria Chr 7 and Cyclina sinensis Chr 14. Tandem duplication MmHSP70 gene pairs experienced different levels of purifying selection, which could be an important source of sequence and functional constraints. MmHSP70 genes showed tissue-specific and stress-specific expression. Most tandem duplication HSP70 gene pairs had high expression under hypoxia stress. HSP70 B2 tandem duplication gene pairs showed significantly increased expression under heat plus severe hypoxia stress. This study provided a comprehensive understanding of the MmHSP70 gene family in the M. mercenaria and laid a significant foundation for further studies on the functional characteristics of MmHSP70 genes during exposure to heat and hypoxia stress.

Developmental Expression Pattern of the Piwi1 Gene, Timing of Sex Differentiation and Maturation in Artificially Produced Juvenile Boring Giant Clam, Tridacna crocea - Yinyin Zhou; Yunqing Li; Qingliang Liao; Gongpengyang Shi; Yanpin Qin; Yuehuan Zhang; Haitao Ma; Jun Li; Ziniu Yu (Frontiers in Marine Science, 2022)
P-element-induced wimpy testis ( Piwi ) is a key gene involved in germ cell development in a diverse range of organisms. However, in giant clams, the function of Piwi remains unclear. In the present study, we isolated the full-length cDNA of Piwi ortholog ( Tc-Piwi1 ) and analyzed its expression patterns in the gonads of adult and juvenile Tridacna crocea . The results of qPCR showed that the transcript of Tc-Piwi1 was mainly expressed in gonad tissue. In addition, the relative expression level of Tc-Piwi1 increased with the proliferation of male and female germ cells during the adult gonad development stage, suggesting that Tc-Piwi1 might be involved in gametogenesis. In situ hybridization revealed that Tc-Piwi1 RNA was located in female and male germ cells and strongly expressed in male germ cells in the early stage. Furthermore, immunohistochemical experiments further confirmed that Tc-Piwi1 was mainly located in primordial germ cells (PGCs), germ stem cells (GSCs), and female and male germ cells of early development, so it could be used as a marker gene of T. crocea germ cells. Whole-mount in situ hybridization suggested that Tc-Piwi1 was of maternal origin and located in two clusters of cells in the trochophore-larvae stage, implying that these cells might be putative PGCs during the embryo development. Finally, Tc-Piwi1 was used as a molecular marker to elucidate the gonadal formation, sex differentiation, and gonadal maturation process of juvenile T. crocea for the first time in the Tridacna family. Collectively, all these results revealed that Tc-Piwi1 was involved in germline formation and sex differentiation in T. crocea .

Multiple indeterminate domain (IDD)–DELLA1 complexes participate in gibberellin feedback regulation in peach - Yajun Jiang; Jiajia Chen; Xianbo Zheng; Bin Tan; Xia Ye; Wei Wang; Langlang Zhang; Jidong Li; Zhiqian Li; Jun Cheng; Jiancan Feng (Plant Molecular Biology, 2022)

Kai-Xin-San Inhibits Tau Pathology and Neuronal Apoptosis in Aged SAMP8 Mice - Ya-Nan Jiao; Jing-Sheng Zhang; Wen-Jun Qiao; Shu-Yu Tian; Yi-Bin Wang; Chun-Yan Wang; Yan-Hui Zhang; Qi Zhang; Wen Li; Dong-Yu Min; Zhan-You Wang (Molecular Neurobiology, 2022)
Alzheimer’s disease (AD) is an age-related neurological disorder. Currently, there is no effective cure for AD due to its complexity in pathogenesis. In light of the complex pathogenesis of AD, the traditional Chinese medicine (TCM) formula Kai-Xin-San (KXS), which was used for amnesia treatment, has been proved to improve cognitive function in AD animal models. However, the active ingredients and the mechanism of KXS have not yet been clearly elucidated. In this study, network pharmacology analysis predicts that KXS yields 168 candidate compounds acting on 863 potential targets, 30 of which are associated with AD. Enrichment analysis revealed that the therapeutic mechanisms of KXS for AD are associated with the inhibition of Tau protein hyperphosphorylation, inflammation, and apoptosis. Therefore, we chose 7-month-old senescence-accelerated mouse prone 8 (SAMP8) mice as AD mouse model, which harbors the behavioral and pathological hallmarks of AD. Subsequently, the potential underlying action mechanisms of KXS on AD predicted by the network pharmacology analyses were experimentally validated in SAMP8 mice after intragastric administration of KXS for 3 months. We observed that KXS upregulated AKT phosphorylation, suppressed GSK3β and CDK5 activation, and inhibited the TLR4/MyD88/NF-κB signaling pathway to attenuate Tau hyperphosphorylation and neuroinflammation, thus suppressing neuronal apoptosis and improving the cognitive impairment of aged SAMP8 mice. Taken together, our findings reveal a multi-component and multi-target therapeutic mechanism of KXS for attenuating the progression of AD, contributing to the future development of TCM modernization, including KXS, and broader clinical application. Graphical abstract

Metagenomic analysis reveals wide distribution of phototrophic bacteria in hydrothermal vents on the ultraslow-spreading Southwest Indian Ridge - Hong Chen; Deng Hui Li; Ai Jun Jiang; Xue Gong Li; Shi Jun Wu; Jian Wei Chen; Meng Jie Qu; Xiao Qing Qi; Jie Dai; Rui Zhao; Wei-Jia Zhang; Shan Shan Liu; et al. (Marine Life Science & Technology, 2022)

The Effects of Ground and Treadmill Running on Energy Metabolism and Muscle Contractile Properties: A Randomized Cross-Over Study - Yuan Zhou; Jian-gang Chen; Xiao-long Li; Xin-liang Pan; Yi-zheng Zhou; Zheng-ao Li; Zhi-cheng Liang; Jia-min Long; Ming-ze Qin; Jing Zhang; Bing Shi; Bing-jun Wan; et al. (Journal of Science in Sport and Exercise, 2022)
Purpose This study aimed to compare the effects of ground and treadmill running on energy metabolism and muscle contractile properties, providing a basis for the general public to choose running venues. Methods Ten male college students (age, 20.10 ± 1.53 years; height, 176.20 ± 5.49 cm; weight, 72.14 ± 8.25 kg; body fat percent, 12.41% ± 4.65%) were recruited in this study. Energy expenditure (EE) was measured using the accelerometer (GT9X) combined with specific estimation equations. Average heart rate (HR) was measured using a heart rate band (Polar). Muscle contractile properties were assessed by measuring muscle displacement (Dm) and contraction velocity (Vc) using tensiomyography (TMG-S1). Blood glucose (Glu) and lactate (Lac) were measured by portable devices (eB-G and Lactate Scout). The running speed was 9 km/h and the duration was 25 min. Two-way ANOVA (protocol × time) was used to analyze the effect of running protocols on energy metabolism and muscle contractile properties. Results EE of treadmill running was significantly higher than EE of ground running (protocol main effect, P < 0.001), and HR of treadmill running was significantly higher than that of ground running in the first testing time (protocol simple effect, P = 0.026; protocol × time interaction P = 0.043). The decrease in Dm of the rectus femoris after treadmill running was significantly higher than that of ground running (protocol main effect, P = 0.009). The interaction of different running protocols and testing times on Lac was significant ( P = 0.025), but all results of the simple effects analysis were not statistically significant ( P > 0.05). Conclusion Our study found a difference in energy expenditure between treadmill and ground running at 9 km/h with duration of 25 min. In addition, treadmills are more likely to cause a decrease in muscle displacement distance of the rectus femoris measured after exercise than ground running. Future studies are needed to further investigate whether the differences are induced by internal metabolism or the environmental conditions of running.

Marker-assisted introgression of Xa39 improve rice resistance to five Xanthomonas oryzae pv. oryzae strains - Yingyao Shi; Wei Zeng; Junping Xie; Fan Zhang; Dalong Zhuo; Lingling Gao; Mingfu Zhao; Xiaorong Shi; Minghui Xu; Zhenzhen Zheng; Zhiqi Hao; Hongyan Yuan; et al. (Journal of Plant Pathology, 2022)

The Status of Polychlorinated Biphenyls (PCBs) Extract from Zhanjiang Mangrove Sediments and the Effects on Tissue Structure and Inflammatory Cytokines in Zebrafish Liver - Aftab Qamar; Javaria Waheed; Sahar Ghulam Mohyuddin; Zhi-Bao Chen; Dan-Ju Kang; Zhang Li; Glen Hay Anthony; Ravi Gooneratne; Fang-Hong Nie; Jin-Jun Chen (Bulletin of Environmental Contamination and Toxicology, 2022)

Serum Copper and Zinc Levels and Colorectal Cancer in Adults: Findings from the National Health and Nutrition Examination 2011–2016 - Chaofeng Zhang; Renqiang Cheng; Jun Ding; Xingjia Li; Hongwen Niu; Xing Li (Biological Trace Element Research, 2022)

RhoGDI2 induced malignant phenotypes of pancreatic cancer cells via regulating Snail expression - Bin Yi; You Hu; Dongming Zhu; Jun Yao; Jian Zhou; Yi Zhang; Zhilong He; Lifeng Zhang; Zixiang Zhang; Jian Yang; Yuchen Tang; Yujie Huang; et al. (Genes & Genomics, 2022)

Soil and structure deformation during deep foundation pit excavation in soft clay: case study and sensitivity analysis - Angran Tian; Jun Ju; Haolong Zhang; Peng Yin; Qiang Tang; Wenwen Li (Arabian Journal of Geosciences, 2022)

Correction to: Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Effects of Shellfish and Macro-Algae IMTA in North China on the Environment, Inorganic Carbon System, Organic Carbon System, and Sea–Air CO2 Fluxes - Yi Liu; Jihong Zhang; Wenguang Wu; Yi Zhong; Hongmei Li; Xinmeng Wang; Jun Yang; Yongyu Zhang (Frontiers in Marine Science, 2022)
Shellfish and macro-algae integrated multi-trophic aquaculture (IMTA) contribute greatly to the sustainability of aquaculture. However, the effects of large-scale shellfish and macro-algae aquaculture on the functions of the ocean carbon sink are not clear. To clarify these effects, we studied the spatial and temporal changes of inorganic and organic carbon systems in seawater under different aquaculture modes (monoculture or polyculture of shellfish and macro-algae) in Sanggou Bay, together with the variation of other environmental factors. The results show that the summertime dissolved oxygen (DO) concentration in the shellfish culture zone was significantly lower than other zones ( p < 0.05), with a minimum value of 7.07 ± 0.25 mg/L. The variation of pH and total alkalinity (TA) were large across different culture modes, and the seawater in the shellfish culture zone had the lowest pH and TA than the other zones. Seasonal environment and aquaculture modes significantly affected the variation of dissolved inorganic carbon (DIC), CO 2 partial pressure ( p CO 2 ), dissolved organic carbon (DOC), and particulate organic carbon (POC) concentrations. The highest values of DIC, p CO 2 , and POC appeared in summer, and the lowest appeared in winter. For DOC concentration, the lowest value appeared in autumn. Spatially, DIC and p CO 2 were highest in the shellfish culture zone and lowest in the macro-algae culture zone, DOC was highest in the macro-algae culture zone and lowest in the shellfish culture zone, and POC was lower in the shellfish culture zone and macro-algae culture zone and higher in the remaining zones. The results of sea–air CO 2 fluxes showed that except for the shellfish culture zone during summertime, which released CO 2 to the atmosphere, all culture zones were the sinks of atmospheric CO 2 during the culture period, with the whole bay being a strong CO 2 sink during autumn and winter. In summary, large-scale shellfish–macro-algae IMTA plays an important role in the local carbon cycle and contributes to mitigating ocean acidification and hypoxia.

Study on the Individual Coloring Mechanism of Iridescent Cells in the Mantle of the Boring Giant Clam, Tridacna crocea - Yunqing Li; Yinyin Zhou; Jinkuan Wei; Gongpengyang Shi; Qingliang Liao; Shuming Guo; Zihua Zhou; Jun Li; Yanping Qin; Haitao Ma; Ziniu Yu; Yuehuan Zhang (Frontiers in Marine Science, 2022)
Giant clams are marine bivalves that inhabit Indo-Pacific coral reefs. The boring giant clam, Tridacna crocea , exhibits bright and conspicuous mantle coloration based on the specialized cells (iridocytes) that generate structural colors. In order to illustrate the coloring mechanism of individual iridocytes, the reflection spectra curve of iridocytes was obtained by a micro-hyperspectral imager. TEM images were obtained to show the inner nanostructures of iridocytes. FDTD simulation was conducted to analyze the relationship between the color of iridocytes and the unique lamellar structure. We found that the laminae in the regular arrangement within cells govern the coloration of individual iridocytes. With the gradual increase of lamellar thickness and spacing, the color of the structure varies from bright violet to orange-red, forming a full visible spectrum. This study provides a new understanding of the various colors produced by individual iridocytes.

Chromosome-Scale Assembly and Characterization of the Albino Northern Snakehead, Channa argus var. (Teleostei: Channidae) Genome - Chaowei Zhou; Yan Li; Yan Zhou; Yu Zou; Dengyue Yuan; Xingxing Deng; Luo Lei; Jian Su; Chengke Zhu; Hua Ye; Hui Luo; Guangjun Lv; et al. (Frontiers in Marine Science, 2022)
Northern snakehead, Channa argus ( C. argus ), is an important economic and ecological fish species. The wild population of the species was sharply declined in the last decade. A high-quality reference genome could lay a solid foundation for the genetic and conservation studies for C. argus . In this work, we report a chromosomal genome assembly with PacBio and Hi-C technology using the albino northern snakehead, a color variety of C. argus . A 644.1-Mb genome with 24 chromosomes was obtained with a contig and scaffold N50 of 11.78 and 27.8 Mb, respectively. We inferred that C. argus diverged from A. testudineus around 85.6 million years ago. 514 expanded gene families and 214 positively selected genes were identified in the C. argus genome. The chromosome-level genome provides a valuable high-quality genomic resource for population, as well as genetic and evolutionary studies for C. argus and other species in Channidae.

Dilatancy behaviour of rockfill materials and its description - Wan-Li Guo; Zheng-Yin Cai; Ying-Li Wu; Chen Zhang; Jun-Jie Wang (European Journal of Environmental and Civil Engineering, 2022)

A new sesquiterpene from mangrove endophytic fungus Aspergillus sp. GXNU-MA1 - Dexiong Zhou; Wenxiu Zhang; Lili Hao; Xiaoya Qin; Ruiyun Yang; Jun Li; Xishan Huang (Natural Product Research, 2022)

Quinolizidine alkaloids from the roots of Sophora flavescens - Jian-Chun Li; Zhi-Jun Zhang; Dan Liu; Ming-Yan Jiang; Rong-Tao Li; Hong-Mei Li (Natural Product Research, 2022)

A new depsidone derivative from mangrove endophytic fungus Aspergillus sp. GXNU-A9 - Lili Hao; Dexiong Zhou; Xiaoya Qin; Wenxiu Zhang; Ruiyun Yang; Jun Li; Xishan Huang (Natural Product Research, 2022)

Dissection of the practical soybean breeding pipeline by developing ZDX1, a high-throughput functional array - Rujian Sun; Bincheng Sun; Yu Tian; Shanshan Su; Yong Zhang; Wanhai Zhang; Jingshun Wang; Ping Yu; Bingfu Guo; Huihui Li; Yanfei Li; Huawei Gao; et al. (Theoretical and Applied Genetics, 2022)
Key message We developed the ZDX1 high-throughput functional soybean array for high accuracy evaluation and selection of both parents and progeny, which can greatly accelerate soybean breeding. Abstract Microarray technology facilitates rapid, accurate, and economical genotyping. Here, using resequencing data from 2214 representative soybean accessions, we developed the high-throughput functional array ZDX1, containing 158,959 SNPs, covering 90.92% of soybean genes and sites related to important traits. By application of the array, a total of 817 accessions were genotyped, including three subpopulations of candidate parental lines, parental lines and their progeny from practical breeding. The fixed SNPs were identified in progeny, indicating artificial selection during the breeding process. By identifying functional sites of target traits, novel soybean cyst nematode-resistant progeny and maturity-related novel sources were identified by allele combinations, demonstrating that functional sites provide an efficient method for the rapid screening of desirable traits or gene sources. Notably, we found that the breeding index (BI) was a good indicator for progeny selection. Superior progeny were derived from the combination of distantly related parents, with at least one parent having a higher BI. Furthermore, new combinations based on good performance were proposed for further breeding after excluding redundant and closely related parents. Genomic best linear unbiased prediction (GBLUP) analysis was the best analysis method and achieved the highest accuracy in predicting four traits when comparing SNPs in genic regions rather than whole genomic or intergenic SNPs. The prediction accuracy was improved by 32.1% by using progeny to expand the training population. Collectively, a versatile assay demonstrated that the functional ZDX1 array provided efficient information for the design and optimization of a breeding pipeline for accelerated soybean breeding.

The solar wind plasma upstream of Mars observed by Tianwen-1: Comparison with Mars Express and MAVEN - Kai Fan; Limei Yan; Yong Wei; Aibing Zhang; Linggao Kong; Markus Fränz; Fei He; Lihui Chai; Chongjing Yuan; Yuqi Wang; Jun Zhong; Zhaojin Rong; et al. (Science China Earth Sciences, 2022)

Changes of community composition strengthen the positive effects of nitrogen deposition on litter N:P stoichiometry in a semi-arid grassland - Shuang-Li Hou; Jun-Jie Yang; Jiang-Xia Yin; Hai-Wei Wei; Yan-Yu Hu; Zhi-Wei Zhang; Guo-Jiao Yang; Xiao-Tao Lü (Plant and Soil, 2022)

Melatonin inhibits autophagy in TM3 cells via AKT/FOXO1 pathway - Zhiqiang Li; Hongtao Wang; Kaiyan Zhang; Jing Zhao; Hongyu Liu; Xin Ma; Jing Guo; Jun Wang; Wenfa Lu (Molecular Biology Reports, 2022)

Cassiterite oxygen isotopes in magmatic-hydrothermal systems: in situ microanalysis, fractionation factor, and applications - Yang Li; Sheng He; Rong-Qing Zhang; Xian-Wu Bi; Lian-Jun Feng; Guo-Qiang Tang; Wen-Zhong Wang; Fang Huang; Xian-Hua Li (Mineralium Deposita, 2022)

Sodium tanshinone IIA sulfonate improves cognitive impairment via regulating Aβ transportation in AD transgenic mouse model - Hui-Han Ma; Can Wan; Lu-Di Zhang; Rong-Rong Zhang; Dong Peng; Li-Jun Qiao; Shi-Jie Zhang; Ye-Feng Cai; Hong-Qiang Huang (Metabolic Brain Disease, 2022)

Dihydroartemisinin ameliorates chronic nonbacterial prostatitis and epithelial cellular inflammation by blocking the E2F7/HIF1α pathway - Yan Zhou; Jun-hao Wang; Jian-peng Han; Jian-yong Feng; Kuo Guo; Fei Du; Wen-bin Chen; Yong-zhang Li (Inflammation Research, 2022)

Cloning and expression of kiss genes and regulation of feeding in Siberian sturgeon (Acipenser baerii) - Shaoqi Xu; Mei Wang; Ya Li; Ni Tang; Xin Zhang; Hu Chen; Shupeng Zhang; Yanling Liu; Jun Wang; Defang Chen; Zhiqiong Li (Fish Physiology and Biochemistry, 2022)

Short-term effect of ambient air pollutant change on the risk of tuberculosis outpatient visits: a time-series study in Fuyang, China - Xin-Qiang Wang; Ying-Qing Li; Cheng-Yang Hu; Kai Huang; Kun Ding; Xiao-Jing Yang; Xin Cheng; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Yong-Zhong Zhang; Zhen-tao Ding; et al. (Environmental Science and Pollution Research, 2022)

Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma - Peipei Han; Shu Wu; Limei Li; Danping Li; Jun Zhao; Haishan Zhang; Yifang Wang; Xuemin Zhong; Zhe Zhang; Ping Li; Liudmila Matskova; Xiaoying Zhou (Genes & Genomics, 2022)

Complete genome analysis of a novel picorna-like virus from a ladybird beetle (Cheilomenes sexmaculata) - Yu-Juan He; Zhuang-Xin Ye; Jian-Ping Chen; Chuan-Xi Zhang; Gang Lu; Jun-Min Li (Archives of Virology, 2022)

Complete genome sequence of a novel arlivirus from a yellow spotted stink bug (Erthesina fullo (Thunberg, 1783)) - Zhuang-Xin Ye; Shao-Min Wang; Gang Lu; Jian-Ping Chen; Chuan-Xi Zhang; Liao-Yuan Xu; Jun-Min Li (Archives of Virology, 2022)

Retraction Note: The evolution of spatial and temporal patterns of Zhengzhou ecological network based on MSPA - Xiao Zhe-tao; Zhang Wan-ying; HAO Li-jun (Arabian Journal of Geosciences, 2022)

Petrogenesis and tectonic implications of Late Triassic dikes from the Suolun within the central Great Xing’an Range, NE China: constraints from geochronology and geochemistry - Yan Li; Hai-yin Xi; Feng-Jun Nie; Yao Zhang; Yue-ye Fan; Dong-yu Fang; Zhao-Bin Yan (Arabian Journal of Geosciences, 2022)

Two new amide glycosides with anti-inflammatory activity from the leaves of Streblus ilicifolius (Vidal) Corner - Yan Huang; Xishan Huang; Guobiao Tian; Wenxiu Zhang; Shanshan Su; Xia Xu; Jun Li; Buming Liu (Natural Product Research, 2022)

Water Circulation Driven by Cold Fronts in the Wax Lake Delta (Louisiana, USA) - Qian Zhang; Chunyan Li; Wei Huang; Jun Lin; Matthew Hiatt; Victor H. Rivera-Monroy (Journal of Marine Science and Engineering, 2022)
Atmospheric cold fronts can periodically generate storm surges and affect sediment transport in the Northern Gulf of Mexico (NGOM). In this paper, we evaluate water circulation spatiotemporal patterns induced by six atmospheric cold front events in the Wax Lake Delta (WLD) in coastal Louisiana using the 3-D hydrodynamic model ECOM-si. Model simulations show that channelized and inter-distributary water flow is significantly impacted by cold fronts. Water volume transport throughout the deltaic channel network is not just constrained to the main channels but also occurs laterally across channels accounting for about a quarter of the total flow. Results show that a significant landward flow occurs across the delta prior to the frontal passage, resulting in a positive storm surge on the coast. The along-channel current velocity dominates while cross-channel water transport occurs at the southwest lobe during the post-frontal stage. Depending on local weather conditions, the cold-front-induced flushing event lasts for 1.7 to 7 days and can flush 32–76% of the total water mass out of the system, a greater range of variability than previous reports. The magnitude of water flushed out of the system is not necessarily dependent on the duration of the frontal events. An energy partitioning analysis shows that the relative importance of subtidal energy (10–45% of the total) and tidal energy (20–70%) varies substantially from station to station and is linked to the weather impact. It is important to note that within the WLD region, the weather-induced subtidal energy (46–66% of the total) is much greater than the diurnal tidal energy (13–25% of the total). The wind associated with cold fronts in winter is the main factor controlling water circulation in the WLD and is a major driver in the spatial configuration of the channel network and delta progradation rates.

Investigation on Natural Infection of Covert Mortality Nodavirus in Large Yellow Croaker, Larimichthys crocea - Tingting Xu; Yuding Fan; Tianchang Jia; Chong Wang; Wei Wang; Jun Li; Qingli Zhang; Cuiluan Yao (Frontiers in Marine Science, 2022)
Covert mortality nodavirus (CMNV) recently became more prevalent, severely affecting farmed shrimps, and also other invertebrates and teleost fish, in the coastal areas of China. For better understanding of its prevalence and susceptibility of large yellow croaker Larimichthys crocea to CMNV, an epidemiological survey was carried out in the main producing areas (Ningbo, Zhejiang, China, and Ningde, Fujian, China) and its offshore feeding grounds in the Southern Yellow Sea. The collected cultured L. crocea individuals showed clinical symptoms such as anorexia and abnormal swimming and diagnosed for CMNV infection by using RT-nPCR assay. The positive rates for CMNV in the collected L. crocea samples from Ningbo, Ningde, and the Yellow Sea were 14.29% (4/28), 20.00% (7/35), and 16.67% (1/6), respectively. Furthermore, CMNV diagnosis using TaqMan probe-based reverse transcription quantitative PCR (TaqMan RT-qPCR) yielded positive rates of 25.00% (7/28), 22.86% (8/35), and 16.67% (1/6) respectively in the above-mentioned samples, and with a range of 12.73–3,108.33 of CMNV copy numbers/μg total RNA. Phylogenetic tree analysis based on the RNA-dependent RNA polymerase (RdRp) and capsid protein genes showed that CMNV isolates from L. crocea samples were clustered tightly with the original isolate of CMNV from Penaeus vannamei . The histopathological studies indicated that severe cellular necrosis occurred in the heart, liver, spleen, eye, and gill of naturally infected fish. Stronger positive signals for CMNV-specific probes appeared in the necrotic cells and tissues in the in situ hybridization (ISH) analysis. Transmission electron microscopy (TEM) revealed the presence of numerous 30 nm diameter CMNV-like viral particles. The purified CMNV suspension could cause a significant cytopathic effect (CPE) in epithelioma papilloma cyprini (EPC) cells and resulted in the formation of typical inclusion bodies, and also visible CMNV particles around the lysed EPC cells under the TEM. Taken together, all results of this study demonstrated that L. crocea is susceptible to CMNV. The prevalence of CMNV and its potential impacts on the wild population of L. crocea see the need for further investigations.

Analysis of heterogeneity in a sedimentary aquifer using Generalized sub-Gaussian model based on logging resistivity - Kaixuan Li; Jichun Wu; Tongchao Nan; Xiankui Zeng; Lihe Yin; Jun Zhang (Stochastic Environmental Research and Risk Assessment, 2022)

Mechanism of Adipose-Derived Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying miR-21-5p in Hyperoxia-Induced Lung Injury - Yunfei Wu; Zhihui Zhang; Jun Li; Hai Zhong; Rui Yuan; Zihui Deng; Xu Wu (Stem Cell Reviews and Reports, 2022)

Transcriptomic analyses reveal the effect of nitric oxide on the lateral root development and growth of mangrove plant Kandelia obovata - Ming-Yue Wei; Huan Li; You-Hui Zhong; Zhi-Jun Shen; Dong-Na Ma; Chang-Hao Gao; Yi-Ling Liu; Wen-Hua Wang; Jing-Ya Zhang; Yan-Ping You; Hai-Lei Zheng (Plant and Soil, 2022)

RhoGEF Trio Regulates Radial Migration of Projection Neurons via Its Distinct Domains - Chengwen Wei; Mengwen Sun; Xiaoxuan Sun; Hu Meng; Qiongwei Li; Kai Gao; Weihua Yue; Lifang Wang; Dai Zhang; Jun Li (Neuroscience Bulletin, 2022)
The radial migration of cortical pyramidal neurons (PNs) during corticogenesis is necessary for establishing a multilayered cerebral cortex. Neuronal migration defects are considered a critical etiology of neurodevelopmental disorders, including autism spectrum disorders (ASDs), schizophrenia, epilepsy, and intellectual disability (ID). TRIO is a high-risk candidate gene for ASDs and ID. However, its role in embryonic radial migration and the etiology of ASDs and ID are not fully understood. In this study, we found that the in vivo conditional knockout or in utero knockout of Trio in excitatory precursors in the neocortex caused aberrant polarity and halted the migration of late-born PNs. Further investigation of the underlying mechanism revealed that the interaction of the Trio N-terminal SH3 domain with Myosin X mediated the adherence of migrating neurons to radial glial fibers through regulating the membrane location of neuronal cadherin (N-cadherin). Also, independent or synergistic overexpression of RAC1 and RHOA showed different phenotypic recoveries of the abnormal neuronal migration by affecting the morphological transition and/or the glial fiber-dependent locomotion. Taken together, our findings clarify a novel mechanism of Trio in regulating N-cadherin cell surface expression via the interaction of Myosin X with its N-terminal SH3 domain. These results suggest the vital roles of the guanine nucleotide exchange factor 1 (GEF1) and GEF2 domains in regulating radial migration by activating their Rho GTPase effectors in both distinct and cooperative manners, which might be associated with the abnormal phenotypes in neurodevelopmental disorders.

The parasitoid Aenasius arizonensis prefers its natural host but can parasitize a nonnatural host in the laboratory: an opportunity for control of a new invasive mealybug - Jun Huang; Fuying Zhi; Juan Zhang; Xiaowei Li; Yaobin Lu (Journal of Pest Science, 2022)
The absence of natural enemies in newly invaded areas is a key factor in the successful invasion of alien species. Whether a specific parasitoid can be domesticated to attack a nonnatural host that has no reported parasitic enemies in invasive areas remains unclear. Here, we analyzed two invasive mealybugs (PSS- Phenacoccus solenopsis and PSI- Phenacoccus solani ) and a specific parasitoid of P. solenopsis ( Aenasius arizonensis ) to verify this hypothesis under laboratory conditions. A. arizonensis preferred to parasitize PSS, but after 6 h, it also parasitized PSI female adults. The number of visits and parasitism rate was significantly higher for PSS than for PSI. However, the contact time was influenced by the natal host. The chemical volatiles emitted by the two hosts were different and may be an important factor for host choice. Offspring fitness, measured as emergence time, longevity, and hind tibia length, in those emerging from PSS was better in those emerging from PSI, but the emergence rate was higher in the latter. We supposed that A. arizonensis accepts and parasitizes low-quality hosts not because of an "incomplete" evaluation but because it may be more profitable to parasitize than not given circumstances; this may provide an opportunity for the control of a new invasive mealybug in the future.

Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China - Tie-Ning Zhang; Qi-Jun Wu; Yan-Hong Huang; Jing Li; Zong-Jiao Chen; Li-Li Li; Yan-Ling Chen; Shu Liu; Cheng-Zhi Jiang; Yu-Hong Zhao (Environmental Science and Pollution Research, 2022)

Remarkable enhancement in the N2 selectivity of NH3-SCR over the CeNb3Fe0.3/TiO2 catalyst in the presence of chlorobenzene - Pengchao Zang; Jun Liu; Xiaoqing Liu; Guojie Zhang; Jianjun Chen; Junhua Li; Yongfa Zhang (Environmental Science and Pollution Research, 2022)

Polycyclic aromatic hydrocarbons in street dust from different functional areas in Chengdu, China: seasonal variation and health risk assessment - Han-Han Li; Zhan-Biao Yang; Xiao-Xun Xu; Xue-Mei Zhu; Jun-Ren Xian; Yuan-Xiang Yang; Zhang Cheng (Environmental Geochemistry and Health, 2022)

Load transfer laws of tensile anchors in rock masses with weak interlayers based on a shear-slipping updating model - Yan Wang; Xin Xiang; Chang-dong Li; Guo-qiang Zhu; Cheng-bin Song; Jin-ye Xian; Jia-jun Zhang (Journal of Mountain Science, 2022)

Haloterrigena gelatinilytica sp. nov., a new extremely halophilic archaeon isolated from salt-lake - Bing-Bing Liu; Nimaichand Salam; Manik Prabhu Narsing Rao; Shuang Cheng; Yuan-Guo Xie; Lai-You Wang; Yuan-ru Zhang; Xin-Yuan Yu; Shu-xian Guo; Wen-Jun Li (Archives of Microbiology, 2022)

Can artificial light promote submerged macrophyte growth in summer? - Chao Xu; Hai-Jun Wang; Yan Li; Chi Xu; Qing Yu; Miao Liu; Miao Zhang; Hong-Zhu Wang; David P. Hamilton; Erik Jeppesen (Aquatic Ecology, 2022)

Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Risk and protection strategies of Amolops wuyiensis intestine against gastrointestinal nematode ( Cosmocercoides wuyiensis n. sp.) infection - Yilin Shu; Yunyun Xie; Shikun Li; Liming Cai; Ying Liu; Yalin Feng; Jun He; Huijuan Zhang; Menglong Ran; Qina Jia; Hailong Wu; Linming Lu (Environmental Microbiology, 2022)
Summary Anuran amphibians are susceptible to infection by intestinal nematodes, but the damage and response mechanisms that occur in their intestines after infection are only partially understood. In this study, the intestinal disruption and response mechanisms in Amolops wuyiensis frogs infected with Cosmocercoides wuyiensis n. sp. were revealed through analysis of the intestinal histopathology, digestive enzyme activity, transcriptome and intestinal microbiota. Tissue section analysis showed histological damage and inflammation in the infected intestine, and the digestive enzyme activity indicated a decrease in digestion and absorption of some nutrients. We found that infection led to differences in the intestinal microbiota composition, including lower diversity and symbiotic relationships. The greater relative abundance of the genera Burkholderia and Rhodococcus may enhance intestinal immunity to resist pathogenic infections. A comparison of the transcriptomes of infected and uninfected intestines revealed 1055 differentially expressed genes. GO enrichment and KEGG pathways analyses suggested that the guts of infected C . wuyiensis n. sp. show enhanced complement activation, cell adhesion molecule function, NOD‐like receptor signalling pathway activity and other innate immunity responses. Among the adaptive immune responses, the intestinal immune network for IgA production was significantly enriched, and the expression of IL‐17D and transforming growth factor beta‐1 genes were upregulated in the infected intestine. These results imply that C . wuyiens is n. sp. infection of A . wuyiensis intestine may trigger innate and adaptive immune responses, which reduce the post‐infection burden. Furthermore, the intestine of A . wuyiensis may also respond to C . wuyiensis n. sp. infection by increasing metallocarboxypeptidase activity and accelerating smooth muscle contraction.

Short-Term Variations in Water Temperature of the Antarctic Surface Layer - Yuyi Hu; Weizeng Shao; Jun Li; Chunling Zhang; Lingqiao Cheng; Qiyan Ji (Journal of Marine Science and Engineering, 2022)
Against the background of global climate change, the warming water temperature of Antarctic surface water (

Genome-wide genetic diversity and IBD analysis reveals historic dissemination routes of pear in China - Xuening Chen; Mingyue Zhang; Manyi Sun; Yueyuan Liu; Shengnan Li; Bobo Song; Mengyan Li; Shaoling Zhang; Runze Wang; Jiaming Li; Kejiao Zhao; Jun Wu (Tree Genetics & Genomes, 2022)

The Relationship of Morphological-Hemodynamic Characteristics, Inflammation, and Remodeling of Aneurysm Wall in Unruptured Intracranial Aneurysms - Qingyuan Liu; Yisen Zhang; Junhua Yang; Yi Yang; Maogui Li; Shanwen Chen; Pengjun Jiang; Nuochuan Wang; Yanan Zhang; Jia Liu; Jun Wu; Shuo Wang (Translational Stroke Research, 2022)

Identification and characterization of QTL for spike morphological traits, plant height and heading date derived from the D genome of natural and resynthetic allohexaploid wheat - Huanwen Xu; Runqi Zhang; Mingming Wang; Linghong Li; Lei Yan; Zhen Wang; Jun Zhu; Xiyong Chen; Aiju Zhao; Zhenqi Su; Jiewen Xing; Qixin Sun; et al. (Theoretical and Applied Genetics, 2022)

Superiority of Adipose-derived CD34 + Cells over Adipose-derived Stem Cells in Promoting Ischemic Tissue Survival - Yan-Jun Liu; Tian-Yu Zhang; Poh-Ching Tan; Pei-Qi Zhang; Yun Xie; Qing-Feng Li; Shuang-Bai Zhou (Stem Cell Reviews and Reports, 2022)

Cancer metabolism and tumor microenvironment: fostering each other? - Yiyuan Yuan; Huimin Li; Wang Pu; Leilei Chen; Dong Guo; Hongfei Jiang; Bo He; Siyuan Qin; Kui Wang; Na Li; Jingwei Feng; Jing Wen; et al. (Science China Life Sciences, 2022)

Fractal analysis of root architecture responses of Saussurea salsa to a gradient of flooding intensity and salinity - Qun Li; Cheng-Zhang Zhao; Jun Wen; Manping Kang; Xiaoya Li (Plant and Soil, 2022)

Seasonality and Sex-Biased Fluctuation of Birth Weight in Tibetan Populations - Yaoxi He; Jun Li; Tian Yue; Wangshan Zheng; Yongbo Guo; Hui Zhang; Li Chen; Chunxia Li; Hongyan Li; Chaoying Cui; Ouzhuluobu; Xuebin Qi; et al. (Phenomics, 2022)

Litter nitrogen concentration changes mediate effects of drought and plant species richness on litter decomposition - Jiang Wang; Yuan Ge; Johannes H. C. Cornelissen; Xiao-Yan Wang; Song Gao; Yi Bai; Tong Chen; Zhong-Wang Jing; Chong-Bang Zhang; Wen-Li Liu; Jun-Min Li; Fei-Hai Yu (Oecologia, 2022)

Protein Kinase C Controls the Excitability of Cortical Pyramidal Neurons by Regulating Kv2.2 Channel Activity - Zhaoyang Li; Wenhao Dong; Xinyuan Zhang; Jun-Mei Lu; Yan-Ai Mei; Changlong Hu (Neuroscience Bulletin, 2022)

Synthesis and evaluation of ursolic acid-based 1,2,4-triazolo[1,5-a]pyrimidines derivatives as anti-inflammatory agents - Tian-Yi Zhang; Chun-Shi Li; Ping Li; Xue-Qian Bai; Shu-Ying Guo; Ying Jin; Sheng-Jun Piao (Molecular Diversity, 2022)

Upregulation of h-TERT and Ki-67 in ectopic endometrium is associated with recurrence of endometriosis - Jie Luo; Zhimin Song; Tao Zhang; Ketan Chu; Jingyi Li; Jianhong Zhou; Jun Lin (Journal of Zhejiang University-SCIENCE B, 2022)

Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout - Ya-Wei Geng; Zhen Zhang; Han Jin; Jun-Long Da; Kai Zhang; Jian-Qun Wang; Yu-Yao Guo; Bin Zhang; Ying Li (Genes & Genomics, 2022)

miR-181b-5p Promotes the Progression of Cholangiocarcinoma by Targeting PARK2 via PTEN/PI3K/AKT Signaling Pathway - Zhe-Long Jiang; Fu-Xing Zhang; Hong-Liang Zhan; He-Jun Yang; Si-Yu Zhang; Zhao-Hui Liu; Yi Jiang; Li-Zhi Lv; Rui-Sheng Ke (Biochemical Genetics, 2022)

Oxidation of organoarsenicals and antimonite by a novel flavin monooxygenase widely present in soil bacteria - Jun Zhang; Jian Chen; Yi‐Fei Wu; Zi‐Ping Wang; Ji‐Guo Qiu; Xiao‐Long Li; Feng Cai; Ke‐Qing Xiao; Xiao‐Xu Sun; Barry P. Rosen; Fang‐Jie Zhao (Environmental Microbiology, 2022)
Summary Arsenic can be biomethylated to form a variety of organic arsenicals differing in toxicity and environmental mobility. Trivalent methylarsenite (MAs(III)) produced in the methylation process is more toxic than inorganic arsenite (As(III)). MAs(III) also serves as a primitive antibiotic and, consequently, some environmental microorganisms have evolved mechanisms to detoxify MAs(III). However, the mechanisms of MAs(III) detoxification are not well understood. In this study, we identified an arsenic resistance ( ars ) operon consisting of three genes, arsRVK , that contribute to MAs(III) resistance in Ensifer adhaerens ST2. ArsV is annotated as an NADPH‐dependent flavin monooxygenase with unknown function. Expression of arsV in the arsenic hypersensitive Escherichia coli strain AW3110 Δars conferred resistance to MAs(III) and the ability to oxidize MAs(III) to MAs(V). In the presence of NADPH and either FAD or FMN, purified ArsV protein was able to oxidize both MAs(III) to MAs(V) and Sb(III) to Sb(V). Genes with arsV ‐like sequences are widely present in soils and environmental bacteria. Metagenomic analysis of five paddy soils showed the abundance of arsV ‐like sequences of 0.12–0.25 ppm. These results demonstrate that ArsV is a novel enzyme for the detoxification of MAs(III) and Sb(III) and the genes encoding ArsV are widely present in soil bacteria.

Anti-Roll Characteristics of Marine Gyrostabilizer Based on Adaptive Control and Hydrodynamic Simulation - Biao Li; Xianku Zhang; Jun Wang; Ning Chen (Journal of Marine Science and Engineering, 2022)
The gyrostabilizer produces the anti-roll effect through the precession output moment generated by a high-speed rotating flywheel. As a floating-base multi-body system composed of ship and gyrostabilizer, the recent research that has only focused on the control strategies or multi-body dynamics is obviously not comprehensive. This study presents an adaptive controller based on the variable gain control strategy for a marine gyrostabilizer installed on a port salvage tug. The variable gain control strategy controlled the flywheel precession output moment of the gyrostabilizer and thereby of the precession process, to reduce the ship roll motion effectively. Furthermore, a full-system hydrodynamic model of a gyrostabilizer-ship-wave based on three-dimensional numerical wave flume technology was innovatively established to evaluate its anti-roll performance under irregular wave conditions. The simulation results show that, for the sea state considered, the increase of spin rate of gyrostabilizer flywheel improved the anti-roll effect significantly. The average anti-roll rate of the gyrostabilizer decreased with the increase of significant wave height, wave period and wave encounter angle.

Two new threonine-containing metabolites from fungus Curvularia inaequalis strain HS-FG-257 - Shao-Yong Zhang; Jian-Song Li; Hui Zhang; Huan Qi; Rui-Jun Wang; Chou-Fei Wu; Li-Qin Zhang; An-Liang Chen; Ji-Dong Wang; Zhi-Kui Hao (Natural Product Research, 2022)

Genetic dissection of quantitative trait loci for grain size and weight by high-resolution genetic mapping in bread wheat (Triticum aestivum L.) - Tao Li; Guangbing Deng; Yan Su; Zhao Yang; Yanyan Tang; Jinhui Wang; Juanyu Zhang; Xvebing Qiu; Xi Pu; Wuyun Yang; Jun Li; Zehou Liu; et al. (Theoretical and Applied Genetics, 2022)

Characterization of Mesenchymal Stem Cells Derived from Bisphosphonate-Related Osteonecrosis of the Jaw Patients’ Gingiva - Mengyu Li; Jiajia Wang; Yejia Yu; Yuqiong Zhou; Yueqi Shi; Wenjie Zhang; Geehun Son; Jing Ge; Jun Zhao; Chi Yang; Shaoyi Wang (Stem Cell Reviews and Reports, 2022)
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a clinical condition that specifically occurs in the oral cavity, characterized by retarded wound healing in oral mucosa accelerating the exposure of bone. Moreover, the pathological mechanism remains poorly understood. Gingival mesenchymal stem cells (GMSCs) play a critical role in gingival healing and soft tissue regeneration. Although previous studies have showed that bisphosphonates (BPs) are highly toxic to healthy GMSC, there is overall lack of direct evidence demonstrating the characterization of GMSCs derived from BRONJ patients. In present study, we isolated GMSCs for the first time from the central area of BRONJ patients’ gingiva (center-BRONJ GMSCs) and the peripheral area (peri-BRONJ GMSCs), and found that they exhibited decreased proliferation, adhesion, migration capacities and underwent early apoptosis in vitro compared control GMSCs. Notably, the central and peripheral BRONJ GMSCs transplantation in a mice excisional skin model also displayed lower cell survival rate and poor healing effects than that of controls. Mechanistically, TGF-β1 signaling pathway was suppressed not only in BRONJ patients’ gingival lesions but also in BRONJ GMSCs transplantation animal model. The results above suggested that under the microenvironment of BRONJ patients, the dysfunction of GMSCs and the suppressed TGF-β1 signaling pathway may be the vital factors in impaired gingival healing, thus contributing to persistent exposure of underlying bone and development of BRONJ. This study provides new insights into the prevention for BRONJ by improving the functions of GMSCs and upregulating TGF-β1 in accelerating gingival wound healing. Graphical Abstract Schematic illustration of the dysfunction of BRONJ GMSCs in vitro and BRONJ GMSCs transplantation in a mice skin model delaying cutaneous wound healing mainly via suppressing TGF-β1 signaling pathway.

LATS1 K751 acetylation blocks activation of Hippo signalling and switches LATS1 from a tumor suppressor to an oncoprotein - Siyuan Yang; Weizhi Xu; Cheng Liu; Jiaqi Jin; Xueying Li; Yuhan Jiang; Lei Zhang; Xianbin Meng; Jun Zhan; Hongquan Zhang (Science China Life Sciences, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

Genetic improvement of grain quality traits in indica inbred rice cultivars developed in South China during 1956–2020 - Xin-Qiao Zhou; Da-Gang Chen; Jie Guo; Ping-Li Chen; Li-Jun Li; Ke Chen; You-Ding Chen; Chuan-Guang Liu; Ze-Min Zhang (Euphytica, 2022)

Seasonal and spatial variations in the phytoplankton community and their correlation with environmental factors in the Jinjiang River Estuary in Quanzhou, China - Yanmei Wu; Peiyong Guo; Haitao Su; Yuxuan Zhang; Jun Deng; Meixian Wang; Yinshi Sun; Yanqi Li; Xiaoyan Zhang (Environmental Monitoring and Assessment, 2022)

A method for precisely predicting satellite clock bias based on robust fitting of ARMA models - Guochao Zhang; Songhui Han; Jun Ye; Ruizhe Hao; Jingchao Zhang; Xia Li; Kun Jia (GPS Solutions, 2022)

First complete mitochondrial genome of Acronictinae (Lepidoptera: Noctuidae): genome description and its phylogenetic implications - Chen Chen; Jun Li; Wenjing Ding; Xuexia Geng; Haijun Zhang; Yuxuan Sun (Biologia, 2022)

Complete genome analysis of a nege-like virus in aphids (Astegopteryx formosana) - Xiao-Di Zhang; Gang Lu; Zhuang-Xin Ye; Jian-Ping Chen; Chuan-Xi Zhang; Jun-Min Li (Archives of Virology, 2022)

Alteribacter salitolerans sp. nov., isolated from a saline-alkaline soil - Shuang Wang; Lei Sun; Manik Prabhu Narsing Rao; Guo-Hong Liu; Pin-Jiao Jin; Zhou-Yan Dong; Zheng-Han Lian; Xiao-Yu Hao; Ming-Yi Zhang; Wen-Jun Li (Archives of Microbiology, 2022)

Mesorhizobium xinjiangense sp. nov., isolated from rhizosphere soil of Alhagi sparsifolia - Dong Meng; Yu-Ling Liu; Jun-Jie Zhang; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Heng Meng; Zong-Jun Du; Wei-Min Li; Qiang Li (Archives of Microbiology, 2022)

Environmental drivers of phytoplankton crops and taxonomic composition in northeastern Antarctic Peninsula adjacent sea area - Yubin Feng; Dong Li; Jun Zhao; Zhengbing Han; Jianming Pan; Gaojing Fan; Haisheng Zhang; Ji Hu; Haifeng Zhang; Jiaqi Wu; Qiuhong Zhu (Acta Oceanologica Sinica, 2022)

Responses of soil pH to no‐till and the factors affecting it: A global meta‐analysis - Xin Zhao; Cong He; Wen‐Sheng Liu; Wen‐Xuan Liu; Qiu‐Yue Liu; Wei Bai; Li‐Jun Li; Rattan Lal; Hai‐Lin Zhang (Global Change Biology, 2022)
No‐till (NT) is a sustainable option because of its benefits in controlling erosion, saving labor, and mitigating climate change. However, a comprehensive assessment of soil pH response to NT is still lacking. Thus, a global meta‐analysis was conducted to determine the effects of NT on soil pH and to identify the influential factors and possible consequences based on the analysis of 114 publications. When comparing tillage practices, the results indicated an overall significant decrease by 1.33 ± 0.28% in soil pH under NT than that under conventional tillage ( p −1 (−1.83%), or crop residue retention (−1.52%). Changes in organic matter decomposition under undisturbed soil and with crop residue retention might lead to a higher concentration of H + and lower of basic cations (i.e., calcium, magnesium, and potassium), which decrease the soil pH, and consequently, impact nutrient dynamics (i.e., soil phosphorus) in the surface layer under NT. Furthermore, soil acidification may be aggravated by NT within site‐specific conditions and improper fertilizer and crop residue management and consequently leading to adverse effects on soil nutrient availability. Thus, there is a need to identify strategies to ameliorate soil acidification under NT to minimize the adverse consequences.

Fish Composition and Diversity of Four Coral Reefs in the South China Sea Based on Hand-Line Catch - Yuanjie Li; Zuozhi Chen; Jun Zhang (Journal of Marine Science and Engineering, 2021)
To improve the overall understanding of the fish diversity and spatial patterns of major coral reefs in the South China Sea, fish assemblage composition, dominant species, biodiversity indices, and multivariate analysis of community structure were reported for four major coral reefs based on hand-line survey data in May and September 2018. A total of five orders, 21 families, 45 genera and 121 species of fish were recorded with Perciformes (78.5%) being the most diverse. The highest number (5) of dominant species was found near Chenhang Island while the lowest (2) number was detected at Zhubi Reef. The highest abundance index (7.21) occurred at Zhubi Reef, while the Shannon–Wiener diversity (4.80), Pielou’s evenness (0.81), and Simpson’s dominance (0.95) indexes were all highest at Qiliangyu Island. Based on cluster analysis and non-metric multi-dimensional scaling (NMDS), fish communities varied more spatially than seasonally. Our results led us to hypothesize that the habitat complexity and level of anthropogenic disturbance were the main factors affecting the composition of reef-dwelling fish on each coral reef. Topography was likely responsible for most variation in the spatial pattern of fish diversity.

Ocean Acidification Triggers Cell Signaling, Suppress Immune and Calcification in the Pacific Oyster Larvae - Ramadoss Dineshram; Shu Xiao; Ginger Wai Kuen Ko; Jun Li; Kovilingal Smrithi; Vengatesen Thiyagarajan; Yang Zhang; Ziniu Yu (Frontiers in Marine Science, 2021)
Elevated carbon dioxide levels in ocean waters, an anthropogenic stressor, can alter the chemical equilibrium of seawater through a process called ocean acidification (OA). The resultant reduction of pH can be detrimental during the early developmental stages of the commercially important edible Pacific oyster Crassostrea gigas ; the ability of larvae to join a population is likely to be compromised by declining ocean pH. Given this threat, it is important to study the molecular mechanisms that these organisms use to overcome OA stress at the gene expression level. Here, we performed transcriptome profiling in oyster larvae following exposure to ambient (8.1) and reduced (7.4) pH during the pre-settlement growth period (i.e., 18 d post fertilization) using RNA-seq with Illumina sequencing technology. In total, 1,808 differentially expressed genes (DEGs) were identified, 1,410 of which were matched by BLAST against the Swiss-Prot database. Gene ontology classification showed that most of these DEGs were related to ribosomal, calcium ion binding, cell adhesion and apoptotic processes. Pathway enrichment analysis revealed that low pH (7.4) enhanced energy production and organelle biogenesis but prominently suppressed several immune response pathways. Moreover, activation of the MAPK signaling pathway was observed along with inhibition of the Wnt, VEGF, and ErbB pathways, highlighting the fact that the initiation of stress responses is given priority over larval development or shell growth when the larvae cope with low pH. In conclusion, our study demonstrated a unique gene expression profiling approach in studying oyster larval responses to OA, which not only provides comprehensive insights into the mechanisms underlying oyster tolerance to CO 2 -driven decreases in ocean pH but also supplies a valuable genomic resource for further studies in this species.

Contrasting latest Permian intracontinental gabbro and Late Triassic arc gabbro–diorite in the Gangdese constrain the subduction initiation of the Neo-Tethys - Qiu-Huan Li; Kai-Jun Zhang; Li-Long Yan; Xin Jin (International Geology Review, 2021)

Clinical Value of 3D-Printed Navigation Technology Combined with Neuroendoscopy for Intracerebral Hemorrhage - Yuqian Li; Hongyu Cheng; Zhenzhu Li; Haikang Zhao; Jiancai Wang; Peng Wang; Tongxin Jin; Guiyong Zheng; Haoxiang Ye; Shaopeng Li; Jun Zhang (Translational Stroke Research, 2021)

Genome-Wide Identification and Expression Analysis of the Carotenoid Cleavage Oxygenase Gene Family in Five Rosaceae Species - Jianrong Zhao; Jiyu Li; Jun Zhang; Dan Chen; Huping Zhang; Chunyan Liu; Gaihua Qin (Plant Molecular Biology Reporter, 2021)

LCZ696 Possesses a Protective Effect Against Homocysteine (Hcy)-Induced Impairment of Blood–Brain Barrier (BBB) Integrity by Increasing Occludin, Mediated by the Inhibition of Egr-1 - Wenfeng Li; Wenjin Yuan; Dandan Zhang; Shuchun Cai; Jun Luo; Kanghua Zeng (Neurotoxicity Research, 2021)

Hydrogen Sulfide Maintains Good Nutrition and Delays Postharvest Senescence in Postharvest Tomato Fruits by Regulating Antioxidative Metabolism - Ting-Ying Zhong; Gai-Fang Yao; Sha-Sha Wang; Ting-Ting Li; Ke-Ke Sun; Jun Tang; Zhong-Qin Huang; Feng Yang; Yan-Hong Li; Xiao-Yan Chen; Lan-Ying Hu; Hua Zhang; et al. (Journal of Plant Growth Regulation, 2021)

Characterization of the novel hybrid cultivar E25 of Saccharina japonica in the northern farming region of China - Li Su; Ti Feng Shan; Jing Li; Su Qin Gao; Shao Jun Pang; Xiao Fei Leng; Yan Zhang; Ming Fu Zhang; Hong Tao Gao (Journal of Applied Phycology, 2021)

Treatment of the actual landfill leachate in different constructed wetlands through intermittent and varied aeration mode - Yi Wang; Wen-Huai Wang; Heng Zhang; Fei-Long Yan; Jia-Jun Li (Environmental Science and Pollution Research, 2021)

Susceptibility assessment of small, shallow and clustered landslide - Xuemei Liu; Pengcheng Su; Yong Li; Jun Zhang; Taiqiang Yang (Earth Science Informatics, 2021)

Different Changing Patterns of Three NOS–NO System Activities after Ischemia–Reperfusion in Rabbit with AMI - Jun Zhang; Chao Chen; Fengpeng Li; Guangren Gao; Jinguo Fu; Heping Niu; Kai Yu; Lei Wang; Run Guo; Yanfang Wan; Zhanfeng Ma; Qianyu Zhang; et al. (Cell Biochemistry and Biophysics, 2021)

Fitting of magnetic measurements of Swarm satellites based on 3D surface spline model - Liu Shuang; Feng Yan; Jiang Yi; Li Yi-Jun; Zhang Jin-Yuan (Applied Geophysics, 2021)

Stress response mechanisms and description of three novel species Shewanella avicenniae sp. nov., Shewanella sedimentimangrovi sp. nov. and Shewanella yunxiaonensis sp. nov., isolated from mangrove ecosystem - Guo-Hong Liu; Qi Zhang; Manik Prabhu Narsing Rao; Shang Yang; Rong Tang; Huai Shi; Jie-Ping Wang; Guan-Min Huang; Bo Liu; Shun-Gui Zhou; Wen-Jun Li (Antonie van Leeuwenhoek, 2021)

Spatio‐temporal variation of macroinvertebrate metacommunity organization in a monsoon‐climate region - Zhengfei Li; Jani Heino; Zhuoyan Song; Xiaoming Jiang; Jun Wang; Zhenyuan Liu; Xiao Chen; Xingliang Meng; Junqian Zhang; Zhicai Xie (Journal of Biogeography, 2021)
Aim Disentangling the drivers of community assembly and species diversity in space and time is critical to elucidating metacommunity theory. However, our understanding of how metacommunity structuring will change over time remains insufficient, especially in rivers in the monsoon climate zone. We examined whether (1) the idealized metacommunity structure is different among seasons and (2) the relative importance of underlying mechanisms on community assembly varies within and across tributaries as well as among seasons. Location Five tributaries in the Hanjiang River Basin. Taxon Macroinvertebrates. Methods Benthic macroinvertebrates and environmental data were collected seasonally (i.e. spring, summer, autumn and winter) from the same 70 sampling sites. The elements of metacommunity structure (EMS) framework was employed to identify which idealized topology best characterizes the actual metacommunity. Redundancy analysis and variance partitioning procedures were applied to determine key environmental and spatial factors and to examine their relative contributions to variation in community structure in different seasons. Results The best‐fit metacommunity typologies were consistent over time, with metacommunity structure in each season displaying Clementsian gradients, characterized by high degrees of coherence and turnover, and positive boundary clumping. Environmental control prevailed over spatial processes in structuring macroinvertebrate communities, but their relative influence on community variation was context‐dependent. Particularly, environmental filtering was the predominant mechanism at the intermediate spatial scale. However, spatial processes had gradually stronger effects at smaller and larger extents. Main conclusions Both EMS analysis and the variance partitioning approach suggested environmental filtering was the principal structuring processes for macroinvertebrate assemblages throughout the year, although mass effects and dispersal limitation also played significant roles at smaller and larger spatial extents respectively. Considering that the most influential environmental factors shaping macroinvertebrate communities were variable across seasons, we argue that spatio‐temporal investigations would provide more information on community assembly than single snapshot studies.

Alkaloids with acetylcholinesterase inhibitory activity from Corydalis racemosa (Thunb.) Pers - Hui-Na Yao; Zhi-Tian Peng; Yun-Feng Zhang; Di-Fa Liu; Bing-Feng Huang; Peng-Fei Tu; Yun-Fang Zhao; Hui-Xia Huo; Jun Li (Natural Product Research, 2021)

Two new 7, 20-epoxy- ent -kauranes from the aerial parts of Isodon eriocalyx - Shu-Ying Li; Li-Hua Zhu; Zheng-Yun Rao; Chao-Jun Wang; Min Jiang; Jian Zhang; Zhi-Qi Yin (Natural Product Research, 2021)

Fine mapping and validation of a major QTL for grain weight on chromosome 5B in bread wheat - Dehui Zhao; Li Yang; Dan Liu; Jianqi Zeng; Shuanghe Cao; Xianchun Xia; Jun Yan; Xiyue Song; Zhonghu He; Yong Zhang (Theoretical and Applied Genetics, 2021)

Identification and validation of two major QTLs for spike compactness and length in bread wheat (Triticum aestivum L.) showing pleiotropic effects on yield-related traits - Tao Li; Guangbing Deng; Yan Su; Zhao Yang; Yanyan Tang; Jinhui Wang; Xvebing Qiu; Xi Pu; Jun Li; Zehou Liu; Haili Zhang; Junjun Liang; et al. (Theoretical and Applied Genetics, 2021)

Linking circular intronic RNA degradation and function in transcription by RNase H1 - Xiang Li; Jia-Lin Zhang; Yun-Ni Lei; Xiao-Qi Liu; Wei Xue; Yang Zhang; Fan Nan; Xiang Gao; Jun Zhang; Jia Wei; Li Yang; Ling-Ling Chen (Science China Life Sciences, 2021)

The selective TAAR1 partial agonist RO5263397 promoted novelty recognition memory in mice - Ruyan Wu; Jianfeng Liu; Robert Seaman; Bernard Johnson; Yanan Zhang; Jun-Xu Li (Psychopharmacology, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Tetraploid induction of Crassostrea hongkongensis and C. sikamea by inhibiting the polar body 1 release in diploid fertilized eggs - Yanping Qin; Zohaib Noor; Xingyou Li; Haitao Ma; Jun Li; Yinyin Zhou; Riguan Mo; Yuehuan Zhang; Ziniu Yu (Marine Life Science & Technology, 2021)

First report of sunflower leaf spot caused by Curvularia lunata in China - Mandela Elorm Addrah; Bixian Shi; Haoyu Li; Yan Ningning; Jian Zhang; Jun Zhao (Journal of Plant Pathology, 2021)

Exposure to 2,4-dichlorophenol, 2,4,6-trichlorophenol, pentachlorophenol and risk of thyroid cancer: a case-control study in China - Wan-Jun Yang; Hua-Bing Wu; Chi Zhang; Qi Zhong; Ming-Jun Hu; Jia-Liu He; Guo-Ao Li; Zhen-Yu Zhu; Jin-Liang Zhu; Huan-Huan Zhao; Han-Shuang Zhang; Fen Huang (Environmental Science and Pollution Research, 2021)

Comparison of the Bulk and Rhizosphere Soil Prokaryotic Communities Between Wild and Reintroduced Manglietiastrum sinicum Plants, a Threatened Species with Extremely Small Populations - Dai-Fa Su; Qing-Qing Shen; Jun-Yu Yang; Zhi-Ying Li; Wei Xiao; Yong-Xia Wang; Zhang-Gui Ding; Xiao-Long Cui (Current Microbiology, 2021)

An novel energy dissipator with self-recovery capability after deformation for structurally energy-dissipating rock-shed - Qi-jun Xie; Li-jun Su; Hao Bai; Hao Tang; Chong-lei Zhang; Fang-wei Yu (Journal of Mountain Science, 2021)

Halegenticoccus tardaugens sp. nov., an extremely halophilic archaeon isolated from a saline soil - Bing-Bing Liu; Nimaichand Salam; Shuang Cheng; Wen-qing Zhang; Yong-qing Zhou; Shu-xian Guo; Wen-Jun Li (Extremophiles, 2021)

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

Retraction Note to: Real-time water quality prediction model based on variance statistics and measurement of college students’ physical health - Guoqing Zhang; Yu Peng; Jun Li (Arabian Journal of Geosciences, 2021)

Phosphorus rather than nitrogen regulates ecosystem carbon dynamics after permafrost thaw - Guibiao Yang; Yunfeng Peng; Benjamin W. Abbott; Christina Biasi; Bin Wei; Dianye Zhang; Jun Wang; Jianchun Yu; Fei Li; Guanqin Wang; Dan Kou; Futing Liu; et al. (Global Change Biology, 2021)
Ecosystem carbon (C) dynamics after permafrost thaw depends on more than just climate change since soil nutrient status may also impact ecosystem C balance. It has been advocated that nitrogen (N) release upon permafrost thaw could promote plant growth and thus offset soil C loss. However, compared with the widely accepted C‐N interactions, little is known about the potential role of soil phosphorus (P) availability. We combined 3‐year field observations along a thaw sequence (constituted by four thaw stages, i.e., non‐collapse and 5, 14, and 22 years since collapse) with an in‐situ fertilization experiment (included N and P additions at the level of 10 g N m −2 year −1 and 10 g P m −2 year −1 ) to evaluate ecosystem C‐nutrient interactions upon permafrost thaw. We found that changes in soil P availability rather than N availability played an important role in regulating gross primary productivity and net ecosystem productivity along the thaw sequence. The fertilization experiment confirmed that P addition had stronger effects on plant growth than N addition in this permafrost ecosystem. These two lines of evidence highlight the crucial role of soil P availability in altering the trajectory of permafrost C cycle under climate warming.

Induced production of a new polyketide in Penicillium sp. HS-11 by chemical epigenetic manipulation - You-Min Ying; Ling Li; Hang-Fei Yu; Yi-Lian Xu; Lu Huang; Wei Mao; Cui-Ping Tong; Zhi-Dong Zhang; Zha-Jun Zhan; Yun Zhang (Natural Product Research, 2021)

Behaviour of thick marine deposits subjected to vacuum combined with surcharge preloading - Dikang Zhang; Hongtao Fu; Jun Wang; Dongqi Zhu; Xiuqing Hu; Yunguo Du; Changfei Gou; Chaoliang Wang; Mingfeng Li; Hai Wu (Marine Georesources & Geotechnology, 2021)

Genetic and molecular characterization of determinant of six-rowed spike of barley carrying vrs1.a4 - Jin-Hui Wang; Zhen-Mei Xu; Xue-Bing Qiu; Li-Lan Li; Shui-Yang Yu; Tao Li; Yan-Yan Tang; Xi Pu; Juan-Yu Zhang; Hai-Li Zhang; Jun-Jun Liang; Ya-Wei Tang; et al. (Theoretical and Applied Genetics, 2021)

Single cell transcriptomic analysis identifies novel vascular smooth muscle subsets under high hydrostatic pressure - Zhenzhen Chen; Haizeng Zhang; Yingnan Bai; Changting Cui; Shuangyue Li; Wenjie Wang; Yue Deng; Qiannan Gao; Lu Wang; Wei Qi; Lijun Zhang; Yan Yang; et al. (Science China Life Sciences, 2021)

Responses of leaf litter decomposability to nitrogen and phosphorus additions are associated with cell wall carbohydrate composition in a subtropical plantation - Xiang-Min Fang; Xiu-Lan Zhang; Ying-Ying Zong; Wen-Qing Li; Jian-Jun Li; Li-Ping Guo; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

CCN1 gene polymorphisms associated with congenital heart disease susceptibility in Northwest Chinese population from different high-altitude areas - Wenke Yang; Jun Bai; Xinyu Song; Shasha Zhang; Nana Chen; Tao You; Kang Yi; Zhenglin Li; Dingxiong Xie; Xiaodong Xie (Environmental Science and Pollution Research, 2021)

Microplastic Pollution in China, an Invisible Threat Exacerbated by Food Delivery Services - Jun Liu; Ting Zhang; Sarah Piché-Choquette; Guofang Wang; Jun Li (Bulletin of Environmental Contamination and Toxicology, 2021)

Impulsivity in heroin‐dependent individuals: structural and functional abnormalities within frontostriatal circuits - Shicong Wang; Min Zhang; Shuang Liu; Yan Xu; Ziqiang Shao; Longmao Chen; Jun Li; Wenhan Yang; Jun Liu; Kai Yuan (Brain Imaging and Behavior, 2021)

High nitrogen uptake and utilization contribute to the dominance of invasive Spartina alterniflora over native Phragmites australis - Qian-Wei Li; Xiao-Ya Zhang; Jin-Feng Liang; Jun-Qin Gao; Xing-Liang Xu; Fei-Hai Yu (Biology and Fertility of Soils, 2021)

Cloning and functional characterization of two GsSnRK1 gene promoters from wild soybean - Jun Chen; Qiang Li; Pengmin Zhang; Haoran Lu; Ya Bian; Yi Jian; Yizhu Wang; Xiaodong Ding; Jialei Xiao (Plant Biotechnology Reports, 2021)

MiR-137 inhibits the proliferation, invasion and migration of glioma via targeting to regulate EZH2 - Jingshun Gu; Juntong Wang; Aiwu You; Jun Li; Yuyan Zhang; Guomin Rao; Xuehua Ge; Kun Zhang; Xuan Liu; Dongchun Wang (Genes & Genomics, 2021)

Supply‐controlled calcium carbonate dissolution decouples the seasonal dissolved oxygen and pH minima in Chesapeake Bay - Jianzhong Su; Wei‐Jun Cai; Jeremy M. Testa; Jean R. Brodeur; Baoshan Chen; K. Michael Scaboo; Ming Li; Chunqi Shen; Margaret Dolan; Yuan‐Yuan Xu; Yafeng Zhang; Najid Hussain (Limnology and Oceanography, 2021)
Acidification can present a stress on organisms and habitats in estuaries in addition to hypoxia. Although oxygen and pH decreases are generally coupled due to aerobic respiration, pH dynamics may be more complex given the multiple modes of buffering in the carbonate system. We studied the seasonal cycle of dissolved oxygen (DO), pH, dissolved inorganic carbon, total alkalinity, and calcium ion (Ca 2+ ) along the main channel of Chesapeake Bay from May to October in 2016. Contrary to the expected co‐occurrence of seasonal DO and pH declines in subsurface water, we found that the pH decline ended in June while the DO decline continued until August in mid‐Chesapeake Bay. We discovered that aerobic respiration was strong from May to August, but carbonate dissolution was minor in May and June and became substantial in August, which buffered further pH declines and caused the seasonal DO and pH minima mismatch. The rate of calcium carbonate (CaCO 3 ) dissolution was not primarily controlled by the saturation state in bottom water, but was instead likely controlled by the supply of CaCO 3 particles. The seasonal variability of Ca 2+ addition in the mid‐bay was connected to Ca 2+ removal in the upper bay, and the timing of high carbonate dissolution coincided with peak seasonal biomass of upper Bay submerged aquatic vegetation. This study suggests a mechanism for a novel decoupling of DO and pH in estuarine waters associated with CaCO 3 , but future studies are needed to fully investigate the seasonality of physical transport and cycling of CaCO 3 .

Faster recovery of soil biodiversity in native species mixture than in Eucalyptus monoculture after 60 years afforestation in tropical degraded coastal terraces - Wenjia Wu; Luhui Kuang; Yue Li; Lingfeng He; Zhijian Mou; Faming Wang; Jing Zhang; Jun Wang; Zhi’an Li; Hans Lambers; Jordi Sardans; Josep Peñuelas; et al. (Global Change Biology, 2021)
Afforestation is an effective method to restore degraded land. Afforestation methods vary in their effects on ecosystem multifunctionality, but their effects on soil biodiversity have been largely overlooked. Here, we mapped the biodiversity and functioning of multiple soil organism groups resulting from diverse afforestation methods in tropical coastal terraces. Sixty years after afforestation from bare land (BL), plant species richness and the abundance of plant litter (398 ± 85 g m −2 ) and plant biomass (179 ± 3.7 t ha −1 ) in native tree species mixtures (MF) were restored to the level of native forests (NF; 287 ± 21 g m −2 and 243.0 ± 33 t ha −1 , respectively), while Eucalyptus monoculture (EP) only successfully restored the litter mass (388 ± 43 g m −2 ) to the level of NF. Soil fertility in EP and MF was increased but remained lower than in NF. For example, soil nitrogen and phosphorus concentrations in MF (1.2 ± 0.2 g kg −1 and 408 ± 49 mg kg −1 , respectively; p −1 and 523 ± 24 mg kg −1 , respectively; p

Cysestermerol A, a rare stilbene sestermer with significant hypoglycemic activities from Cynodon dactylon - Feng Wang; Li Zhang; Bi-Jun Li; Qiu-Ming Liang; A-Li Chen; Zhen-Feng Fang; Shu-Mei Wang (Natural Product Research, 2021)

A new indole alkaloid with HUVEC proliferation activities from Nauclea officinalis - Shi-Ying Mai; Yong-Hui Li; Xu-Guang Zhang; Yi-Ran Wang; Jun-Qing Zhang; An Jia (Natural Product Research, 2021)

Effects of Melanin Extraction on Biosorption Behavior of Chestnut Shells Towards Methylene Blue - Zhang-Fen Liu; Zhang-Jun Liu; Li-Mei Qie; Zeng-Yu Yao (Water Conservation Science and Engineering, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean - Xiaolong Fang; Xiaoyuan Sun; Xiangdong Yang; Qing Li; Chunjing Lin; Jie Xu; Wenjun Gong; Yifan Wang; Lu Liu; Limei Zhao; Baohui Liu; Jun Qin; et al. (Science China Life Sciences, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Descending Modulation of Spinal Itch Transmission by Primary Somatosensory Cortex - Zi-Han Wu; Han-Yu Shao; Yuan-Yuan Fu; Xiao-Bo Wu; De-Li Cao; Sheng-Xiang Yan; Wei-Lin Sha; Yong-Jing Gao; Zhi-Jun Zhang (Neuroscience Bulletin, 2021)

Inhibited HDAC3 or Elevated MicroRNA-494-3p Plays a Protective Role in Myocardial Ischemia-Reperfusion Injury via Suppression of BRD4 - Wuyang Zheng; Qiang Xie; Ziguan Zhang; Jun Li; Lihuan Fang; Weihua Li (Molecular Neurobiology, 2021)

Octamer transcription factor-1 induces the Warburg effect via up-regulation of hexokinase 2 in non-small cell lung cancer - Zhen Li; Jin Su; Mingming Sun; Jiaqi Song; Huanran Sun; Jun Fan; Guo Chen; Changliang Shan; Qi Qi; Shuai Zhang (Molecular and Cellular Biochemistry, 2021)

Fast estimation method of volumes of landslide deposit by the 3D reconstruction of smartphone images - Lin Fu; Jun Zhu; Wei-lian Li; Ji-gang You; Zhang-yu Hua (Landslides, 2021)

Simple and Sensitive Multi-components Detection Using Synthetic Nitrogen-doped Carbon Dots Based on Soluble Starch - Yuanyuan Hu; Wenxuan Ji; Jinjuan Qiao; Heng Li; Yun Zhang; Jun Luo (Journal of Fluorescence, 2021)

Transcriptome sequencing of wild soybean revealed gene expression dynamics under low nitrogen stress - Qi Sun; Haoran Lu; Qing Zhang; Di Wang; Jun Chen; Jialei Xiao; Xiaodong Ding; Qiang Li (Journal of Applied Genetics, 2021)

Adaptive Total-Variation Regularized Low-Rank Representation for Analyzing Single-Cell RNA-seq Data - Jin-Xing Liu; Chuan-Yuan Wang; Ying-Lian Gao; Yulin Zhang; Juan Wang; Sheng-Jun Li (Interdisciplinary Sciences: Computational Life Sciences, 2021)

Randomized, placebo-controlled trial of orally administered vitamin K1 for warfarin-associated coagulopathy in Chinese patients with mechanical heart valves - Heng Zhang; Mei Li; Xue-lian Ao; Yi-jun Dong; Li Dong (European Journal of Clinical Pharmacology, 2021)

Fabrication of gelatin microspheres containing ammonium hydrogen carbonate for the tunable release of herbicide - He Liu; Zheng Zhang; Jiaxin Li; Wanyu Zang; Qing Yang; Jun Yang (Biotechnology Letters, 2021)

Trace metal contamination in soils from mountain regions across China: spatial distribution, sources, and potential drivers - Haijian Bing; Shaojun Qiu; Xin Tian; Jun Li; He Zhu; Yanhong Wu; Gan Zhang (Soil Ecology Letters, 2021)

RETRACTED ARTICLE: Real-time water quality prediction model based on variance statistics and measurement of college students’ physical health - Guoqing Zhang; Yu Peng; Jun Li (Arabian Journal of Geosciences, 2021)

Gas permeability evolution of granite under confining pressure unloading tests - Dawei Hu; Jun Li; Hui Zhou; Jingjing Lu; Dongdong Ma; Fan Zhang (European Journal of Environmental and Civil Engineering, 2021)