Aqueous-phase chemistry of atmospheric phenolic compounds: A critical review of laboratory studies - Fenghua Li; Shengzhen Zhou; Lin Du; Jun Zhao; Jian Hang; Xuemei Wang (Science of The Total Environment, 2023)

A multi-perspective study of atmospheric urban heat island effect in China based on national meteorological observations: Facts and uncertainties - Decheng Zhou; Shanlei Sun; Yu Li; Liangxia Zhang; Lin Huang (Science of The Total Environment, 2023)

Pod fossils of Albizia (Fabaceae: Caesalpinioideae) from the late Miocene of northern Vietnam and their phytogeographic history - Hung Ba Nguyen; Jian Huang; Truong Van Do; Gaurav Srivastava; Hoa Mai Thi Nguyen; Shu-Feng Li; Lin-Lin Chen; Minh Trung Nguyen; Hung Dinh Doan; Zhe-Kun Zhou; Tao Su (Review of Palaeobotany and Palynology, 2023)

Coupling of the ecosystems in North China with the East Asian summer monsoon rainfall during the Holocene - Jiaju Zhao; Jianbao Liu; Jinzhao Liu; Shengqian Chen; Li Wang; Aifeng Zhou; Zhiping Zhang; Zhongwei Shen; Jie Chen; Lin Chen; Yunning Cao; Jing Hu; et al. (Quaternary Science Reviews, 2023)

Continuous inactivation of human adenoviruses in water by a novel g-C3N4/WO3/biochar memory photocatalyst under light-dark cycles - Chi Zhang; Wei Xiong; Yi Li; Li Lin; Xinyi Zhou; Xinyan Xiong (Journal of Hazardous Materials, 2023)

Rational design of ordered porous nanoparticles for selective extraction of nitrobenzene compounds - Sheng Peng; Minhui Shen; Xiang Li; Yuan-Jun Tong; Jing Guo; Wei Lin; Yu-Xin Ye; Jianqiao Xu; Ningbo Zhou; Fang Zhu; Gangfeng Ouyang (Journal of Hazardous Materials, 2023)

Can hot water injection with chemical additives be an alternative to steam injection: Static and dynamic experimental evidence - Xuan Du; Tong Liu; Changfeng Xi; Bojun Wang; Zongyao Qi; You Zhou; Jiacheng Xu; Lixing Lin; Georgeta Istratescu; Tayfun Babadagli; Huazhou Andy Li (Fuel, 2023)

Dietary cinnamaldehyde improves muscle protein content by promoting muscle fiber growth via PTP1B/IGF1/PI3K/AKTs-TOR/FOXO3a signaling pathway in grass carp (Ctenopharyngodon idella) - Yang Zhou; Pei Wu; Wei-Dan Jiang; Yang Liu; Yan Peng; Sheng-Yao Kuang; Ling Tang; Shu-Wei Li; Lin Feng; Xiao-Qiu Zhou (Food Chemistry, 2023)

Improving probiotic (Lactobacillus casei) viability by encapsulation in alginate-based microgels: Impact of polymeric and colloidal fillers - Qian Li; Hongyi Lin; Jing Li; Lu Liu; Jialu Huang; Yi Cao; Tiantian Zhao; David Julian McClements; Jun Chen; Chengmei Liu; Jiyan Liu; Peiyi Shen; et al. (Food Hydrocolloids, 2023)

Combustible wood dust explosions and impacts on environments and health - A review - Xihe Zhou; Xiaoxu Li; Zhongwen Cui; Lin Wu; Handong Zhou; Xiaoning Lu (Environmental Research, 2023)

Screening of structural and functional alterations in duckweed (Lemna minor) induced by per- and polyfluoroalkyl substances (PFASs) with FTIR spectroscopy - Ying-Lin Wu; Qian Xiong; Ben Wang; You-Sheng Liu; Pei-Liang Zhou; Li-Xin Hu; Fang Liu; Guang-Guo Ying (Environmental Pollution, 2023)

Association between long-term ambient ozone exposure and attention-deficit/hyperactivity disorder symptoms among Chinese children - Peien Zhou; Wangjian Zhang; Yu-Jie Xu; Ru-Qing Liu; Zhengmin Qian; Stephen Edward McMillin; Elizabeth Bingheim; Li-Zi Lin; Xiao-Wen Zeng; Bo-Yi Yang; Li-Wen Hu; Wen Chen; et al. (Environmental Research, 2023)

Activated peroxydisulfate by sorghum straw-based biochar for enhanced tartrazine degradation: Roles of adsorption and radical/nonradical processes - Xiaojuan Chen; Yu Zhou; Jiesen Li; Suresh C. Pillai; Nanthi Bolan; Juhua He; Ning Li; Song Xu; Xin Chen; Qinghua Lin; Hailong Wang (Environmental Pollution, 2023)

Does fiscal expenditure promote green technological innovation in China? Evidence from Chinese cities - Li Wei; Boqiang Lin; Ziwei Zheng; Wei Wu; Yicheng Zhou (Environmental Impact Assessment Review, 2023)

Soil–structure interaction analysis of nuclear power plant considering three-dimensional surface topographic irregularities based on automatic octree mesh - Jianbo Li; Lei Zhou; Shiyi Li; Gao Lin; Zhixin Ding (Engineering Structures, 2023)

Sn2P2S6: A lead-free reversible thermochromic ferroelectric with high near-infrared reflectance - Meixia Wu; Xiao Zhou; Xihui Liang; Yifeng Han; Yonghong Li; Xingan Jiang; Xueyun Wang; Yisheng Chai; Xiang Zhou; Hui Yang; Dan Lin; Ping Xu; et al. (Chemical Engineering Journal, 2023)

Two silver energetic coordination polymers based on a new N-amino-contained ligand: Towards good detonation performance and excellent laser-initiating ability - Qing Lang; Xinyi Li; Jianxin Zhou; Yuangang Xu; Qiuhan Lin; Ming Lu (Chemical Engineering Journal, 2023)

N-type small molecule electron transport materials with D-A-D conjugated core for non-fullerene organic solar cells - Dan Zhou; Yubing Li; Hehui Zhang; Haolan Zheng; Xingxing Shen; Wen You; Lin Hu; Liangjing Han; Yongfen Tong; Lie Chen (Chemical Engineering Journal, 2023)

Near-infrared I/II emission and absorption carbon dots via constructing localized excited/charge transfer state for multiphoton imaging and photothermal therapy - Wen-Bo Zhao; Dan-Dan Chen; Kai-Kai Liu; Yong Wang; Rui Zhou; Shi-Yu Song; Fu-Kui Li; Lai-Zhi Sui; Qing Lou; Lin Hou; Chong-Xin Shan (Chemical Engineering Journal, 2023)

An S-scheme CdS/K2Ta2O6 heterojunction photocatalyst for production of H2O2 from water and air - Cui Lai; Mengyi Xu; Fuhang Xu; Bisheng Li; Dengsheng Ma; Yixia Li; Ling Li; Mingming Zhang; Danlian Huang; Lin Tang; Shiyu Liu; Huchuan Yan; et al. (Chemical Engineering Journal, 2023)

Flexible and highly piezoelectric nanofibers with organic–inorganic coaxial structure for self-powered physiological multimodal sensing - Xingyi Wan; Zhuo Wang; Xinyang Zhao; Quanhong Hu; Zhou Li; Zhong Lin Wang; Linlin Li (Chemical Engineering Journal, 2023)

The coupling of persulfate activation and membrane separation for the effective pollutant degradation and membrane fouling alleviation - Mingzhu Zhou; Junjie Chen; Shuning Yu; Binghong Chen; Cheng Chen; Liguo Shen; Bisheng Li; Hongjun Lin (Chemical Engineering Journal, 2023)

Response of performance, antibiotic resistance genes and bacterial community exposure to compound antibiotics stress: Full nitrification to shortcut nitrification and denitrification - Lin Wang; Zhaoli Wang; Fan Wang; Yue Guan; Dan Meng; Xin Li; Houzhen Zhou; Xudong Li; Yangwu Chen; Zhouliang Tan (Chemical Engineering Journal, 2023)

Intermolecular interaction assisted fabrication of Dion-Jacobson perovskite film with promoted photovoltaic property - Lin Zhang; Ganggang Qi; Yiqing Zhang; Haotian Wu; Xiaoyi Xu; Guanqing Zhou; Haiming Zhu; Xiaodong Li; Gang Wu; Hongzheng Chen (Chemical Engineering Journal, 2023)

Effects of dietary chitosan on the growth, health status and disease resistance of golden pompano (Trachinotus ovatus) - Wei Yu; Yukai Yang; Haimin Chen; Qicun Zhou; Yanwa Zhang; Xiaolin Huang; Zhong Huang; Tao Li; Chuanpeng Zhou; Zhenhua Ma; Qiaer Wu; Heizhao Lin (Carbohydrate Polymers, 2023)

Thin-walled vesicular Triazole-CN-PDI with electronic n→π* excitation and directional movement for enhanced atrazine photodegradation - Rongdi Tang; Hao Zeng; Daoxin Gong; Yaocheng Deng; Sheng Xiong; Ling Li; Zhanpeng Zhou; Jiajia Wang; Chengyang Feng; Lin Tang (Chemical Engineering Journal, 2023)

Investigation on the effectiveness of ventilation dilution on mitigating COVID-19 patients’ secondary airway damage due to exposure to disinfectants - Yifan Li; Yiran Lu; Ying Wang; Li Liu; Hao Zhou; Borong Lin; Zhiyong Peng; Yufeng Yuan (Building and Environment, 2023)

Migration, Health Risks, and Source Apportionment of Heavy Metals in Agricultural Soil–Dustfall–Crop Systems in a Typical Watershed of the Taihu Region, China - Lian Chen; Shenglu Zhou; Cuiming Tang; Guoqing Luo; Zhenjiang Wang; Sen Lin; Jianwu Zhong; Zhiyi Li; Yuan Wang (Water, Air, & Soil Pollution, 2023)

A near-infrared Fluorescent Probe Based on Dicyanisophorone for the Detection of Zinc Ions (Zn2+) in Water and Living Cells - Liqiang Yan; Cuiping Zhou; Jia Li; Hong Yang; Xiongzhi Wu; Lin Li (Journal of Fluorescence, 2023)

Spectrum and mortality of opportunistic infections among HIV/AIDS patients in southwestern China - Sirun Meng; Qiao Tang; Zhiman Xie; Nianning Wu; Yingmei Qin; Rongfeng Chen; Xiaoyu Chen; Xiu Chen; Yueqi Li; Minjuan Shi; Li Ye; Hao Liang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2023)
We describe the opportunistic infections (OIs) of HIV/AIDS to understand the spectrum, mortality, and frequency of multiple coinfected OIs among HIV/AIDS patients in southern China, where OIs are severe. We carried out a retrospective cohort study of hospitalized HIV-infected individuals at the Fourth People’s Hospital of Nanning, Guangxi, China, from Jan. 2011 to May. 2019. The chi-square test was used to analyze cross-infection; the Kaplan‒Meier analysis was used to compare mortality. A total of 12,612 HIV-infected patients were admitted to this cohort study. Among them, 8982 (71.2%) developed one or more OIs. The overall in-hospital mortality rate was 9.0%. Among the patients, 35.6% coinfected one OI, and 64.4% coinfected more than two OIs simultaneously. Almost half of the patients (60.6%) had CD4 + T-cell counts < 200 cells/μL. Pneumonia (39.8%), tuberculosis (35.3%), and candidiasis (28.8%) were the most common OIs. Coinfected cryptococcal meningitis and dermatitis are the most common combined OIs. The rate of anaemia (17.0%) was highest among those common HIV-associated complications. Multiple OIs are commonly found in hospitalized HIV/AIDS patients in southwestern China, which highlights the need for improved diagnosis and treatment.

Correction to: Exposure assessment of aflatoxins and zearalenone in edible vegetable oils in Shandong, China: health risks posed by mycotoxin immunotoxicity and reproductive toxicity in children - Fenghua Li; Xianqi Zhao; Yanni Jiao; Xinglan Duan; Lianlong Yu; Fengjia Zheng; Xiaolin Wang; Lin Wang; Jia‑Sheng Wang; Xiulan Zhao; Tianliang Zhang; Wei Li; et al. (Environmental Science and Pollution Research, 2023)

Cross-level interaction between individual education and regional chemical fertilizer consumption on the risk of hypertension: evidence from the China hypertension survey - Jiajia Li; Zengwu Wang; Shiqi Lin; Lijun Pei; Linfeng Zhang; Xin Wang; Zuo Chen; Congyi Zheng; Yuting Kang; Lu Chen; Haoqi Zhou; Runlin Gao (Environmental Science and Pollution Research, 2023)

Exposure assessment of aflatoxins and zearalenone in edible vegetable oils in Shandong, China: health risks posed by mycotoxin immunotoxicity and reproductive toxicity in children - Fenghua Li; Xianqi Zhao; Yanni Jiao; Xinglan Duan; Lianlong Yu; Fengjia Zheng; Xiaolin Wang; Lin Wang; Jia-Sheng Wang; Xiulan Zhao; Tianliang Zhang; Wei Li; et al. (Environmental Science and Pollution Research, 2023)

Geographical, Sex, Age, and Seasonal Differences in Serum Manganese Status Among Chinese Adults with Hypertension - Hong Chen; Zhixin Cui; Wenhai Lu; Ping Wang; Jia Wang; Ziyi Zhou; Nan Zhang; Zhuo Wang; Tengfei Lin; Yun Song; Lishun Liu; Xiao Huang; et al. (Biological Trace Element Research, 2023)

A new formula of recovery factor for non-equilibrium transport of graded suspended sediment in the Middle Yangtze River - Lin-lin Li; Jun-qiang Xia; Mei-rong Zhou; Shan-shan Deng; Zhi-wei Li (Journal of Mountain Science, 2023)

Dual-response and lysosome-targeted fluorescent probe for viscosity and sulfur dioxide derivatives - Feng Li; Bang-Zhao Zhou; Wen Yao; Shou-Kang Sun; Jun-Ying Miao; Bao-Xiang Zhao; Zhao-Min Lin (Analytica Chimica Acta, 2023)

Selenium attenuates the association of co-exposure to arsenic, cadmium, and lead with cognitive function among Chinese community-dwelling older adults - Bei-Jing Cheng; Jie Sheng; Hong-Li Wang; Yuan Wang; Hong-Juan Cao; Xiu-De Li; Ting-Ting Zhou; Xiang-Long Meng; Huan-Huan Nie; Su-Fang Wang; Dong-Mei Zhang; Gui-Mei Chen; et al. (Environmental Science and Pollution Research, 2022)

Rapid quantitative study of check dam breach floods under extreme rainstorm - Qiang Zhang; Yanlong Li; Shu Yu; Lin Wang; Zuyu Chen; Jiawei Zhou (Natural Hazards, 2022)

Size-specific particulate matter and outpatient visits for allergic conjunctivitis in children: a time-stratified case-crossover study in Guangzhou, China - Jin Zhou; Lijun Fan; Hualiang Lin; Dehui Zheng; Lihong Yang; Dan Zhuo; Jiayang Zhuoma; Huan Li; Shiyu Zhang; Zengliang Ruan (Environmental Science and Pollution Research, 2022)

Effects of exposure to phthalate during early pregnancy on gestational diabetes mellitus: a nested case–control study with propensity score matching - Wei Chen; Caidie He; Xiang Liu; Songlin An; Xia Wang; Lin Tao; Haonan Zhang; Yingkuan Tian; Nian Wu; Pei Xu; Dengqing Liao; Juan Liao; et al. (Environmental Science and Pollution Research, 2022)

Efficacy and Safety of Recombinant Human Prourokinase in Acute Ischemic Stroke: A Phase IIa Randomized Clinical Trial - Haiqing Song; Yuan Wang; Qingfeng Ma; Huisheng Chen; Bo Liu; Yi Yang; Jianguo Zhu; Shigang Zhao; Xiaoping Jin; Yongqiu Li; Yanyong Wang; Runxiu Zhu; et al. (Translational Stroke Research, 2022)

Golden 2-like transcription factor contributes to the major QTL against rice black-streaked dwarf virus disease - Xuejuan Li; Feng Lin; Chenyang Li; Linlin Du; Zhiyang Liu; Wenjuan Shi; Jianying Lv; Xiaoyan Cao; Ying Lan; Yongjian Fan; Yijun Zhou; Tong Zhou (Theoretical and Applied Genetics, 2022)

Dominant complementation of biological pathways in maize hybrid lines is associated with heterosis - Tao Zhou; Rabail Afzal; Muhammad Haroon; Yuting Ma; Hongwei Zhang; Lin Li (Planta, 2022)

Aloe polysaccharide promotes osteogenesis potential of adipose-derived stromal cells via BMP-2/Smads and prevents ovariectomized-induced osteoporosis - Xue-wei Yao; He-dong Liu; Mao-xian Ren; Tian-lin Li; Wen-kai Jiang; Zhi Zhou; Zhi-yi Liu; Min Yang (Molecular Biology Reports, 2022)
Background Aloe polysaccharide (AP) is a type of an active macromolecule of Aloe vera, which contributes to its function. However, whether AP possesses anti-osteoporosis properties is unknown. Methods Adipose-derived stromal cells were treated with different concentrations of AP. Early and late osteogenesis were, respectively, evaluated by ALP and Alizarin Red S staining. The effect of AP on the processes of adipogenesis inhibition in ADSCs was analyzed by oil red O staining. Western blot was used to assess the expression of osteogenic and adipogenic related factors. Then, Noggin was administered to further confirm the mechanism by which AP promotes the osteogenesis of ADSCs. Finally, 40 female SD rats were classified into a bilateral laparotomy group (Sham group) and three bilateral ovariectomy groups: OVX group, OVX + AP group, and OVX + AP + Noggin group. The bilateral rat femurs were collected to perform micro-CT scanning, HE, Masson trichrome, and Oil red O staining. Results The results indicated that AP could increase ALP expression and calcium deposition. Through molecular mechanisms, AP promotes the protein expression of COL1A1, OPN, and ALP in ADSCs, but downregulates the expression of PPARγ. Also, AP directs ADSCs’ fate by stimulating the BMP2/Smads signaling pathway. In vivo, the rat AP-treated had more trabecular bone than the OVX rat, indicating partial protection from cancellous bone loss after treatment with AP. Conclusion Our results show that AP may promote osteogenesis of ADSCs through BMP-2/Smads signaling pathway and inhibits lipogenic differentiation. Thus, AP might be a promising alternative medicine to treat postmenopausal osteoporosis.

Correction to: COX-2/PGE2 Pathway Inhibits the Ferroptosis Induced by Cerebral Ischemia Reperfusion - Yunfei Xu; Ying Liu; Kexin Li; Dun Yuan; Shun Yang; Lin Zhou; Yao Zhao; Shuying Miao; Caihong Lv; Jie Zhao (Molecular Neurobiology, 2022)

Whole-genome sequencing and comparative analysis of Helicobacter pylori GZ7 strain isolated from China - Xiaoyan Zeng; Lin Xiong; Wenling Wang; Yan Zhao; Yuan Xie; Qinrong Wang; Qifang Zhang; Leilei Li; Cencen Jia; Yonghui Liao; Jianjiang Zhou (Folia Microbiologica, 2022)

Therapeutic effects of JLX001 on neuronal necroptosis after cerebral ischemia–reperfusion in rats - Wanting Li; Xue Gou; Dan Xu; Lin Zhou; Fengyang Li; Anqi Ye; Yahui Hu; Yunman Li (Experimental Brain Research, 2022)

PCSK9 Knockdown Can Improve Myocardial Ischemia/Reperfusion Injury by Inhibiting Autophagy - Guangwei Huang; Xiyang Lu; Zonggang Duan; Kai Zhang; Lei Xu; Hailong Bao; Xinlin Xiong; Muzhi Lin; Chao Li; Yunquan Li; Haiyan Zhou; Zhenhua Luo; et al. (Cardiovascular Toxicology, 2022)

Development of a pressure-retaining separation and transfer system for sediment and overlying seawater - Jin Guo; Qixiao Zhou; Yongqiang Ge; Haonan Li; Qiaoling Gao; Ying Wang; Yuan Lin; Jiawang Chen (Frontiers in Marine Science, 2022)
Methane leakage at the interface between sediment and overlying seawater is an important basis for gas hydrate exploration. Therefore, a transfer device with working pressure of 30MPa and corresponding scheme are proposed to separate and transfer the sediment and overlying water inside the sampler under the condition of pressure-retaining. Based on the pressure relief valve with adjustable threshold pressure, the device transfers the overlying water by compressing the internal volume and transfers the sediment by secondary sampling. The performance of transfer device is studied by simulation and experiment. Based on the coupled Eulerian-Lagrangian approach in the Abaqus, the secondary sampling was investigated, and the penetration resistance and coring rate of the secondary sampling tube are 141N and 86.2%, respectively. By using the hydraulic simulation software AMESim, the pressure fluctuation caused by the movement of the mechanism during the transfer process was studied, and the pressure fluctuation amplitude is within 0.89 MPa. Furthermore, the laboratory transfer tests were carried out under high pressure conditions, and meantime, the simulation results are verified. Under the working condition of 30MPa, the device can maintain a pressure loss of no more than 8.0% (2.4MPa) within two hours, maintain pressure fluctuations during the transfer process within 4.8% (1.44MPa), and ensure that the pressure in the culture kettle decreases by 4.7% relative to the pressure in the sampler after the transfer, which shows the feasibility of the device application.

Feasibility Study of a Novel Open Ocean Aquaculture Ship Integrating with a Wind Turbine and an Internal Turret Mooring System - Hanyu Liu; Mingsheng Chen; Zhaolong Han; Hao Zhou; Lin Li (Journal of Marine Science and Engineering, 2022)
Marine aquaculture has been expanded into more remote areas due to the increasing demand for high value-added fish products, bringing more challenges in fuel supply and mooring safety to open ocean aquaculture farms. Therefore, the idea of integrating aquaculture farms with offshore renewable energy has attracted tremendous interest. This study proposes a novel open ocean aquaculture ship integrated with a NREL 5 MW wind turbine. In addition, an internal turret mooring system is installed at the bow of the aquaculture ship, making the wind turbine always face the wind blowing direction due to the weathervaning effect. In this study, a preliminary study of the dynamics and wind power generation of the proposed open ocean aquaculture ship was conducted. The aerodynamic and elastic effects of the wind turbine and the effect of nets under the wave and current behavior on the dynamics of the single-point moored aquaculture ship were investigated. Furthermore, the effects of the dynamics of the aquaculture ship on the power generation of the wind turbine were also studied to investigate the feasibility of the idea to integrate an aquaculture ship with a wind turbine.

Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction - Ping Zhou; Feng Deng; Zi Yang; Canhui Cao; Hongcui Zhao; Fenting Liu; Ke Zhong; Lin Fu; Tianliu Peng; Di Sun; Hui Liu; Rong Li; et al. (Science China Life Sciences, 2022)

Release of Endogenous Brain-derived Neurotrophic Factor into the Lateral Entorhinal Cortex from the Paraventricular Thalamus Ameliorates Social Memory Deficits in a Mouse Model of Alzheimer’s Disease - Yun-Long Xu; Lin Zhu; Zi-Jun Chen; Xiao-Fei Deng; Pei-Dong Liu; Shan Li; Bing-Chun Lin; Chuan-Zhong Yang; Wei Xu; Kui-Kui Zhou; Ying-Jie Zhu (Neuroscience Bulletin, 2022)

Multi-stage melt impregnation and magma–seawater interaction in a slow-spreading oceanic lithosphere: constraints from cumulates in the Lagkorco ophiolite (central Tibet) - Wei-Qi Zhang; Chuan-Zhou Liu; Tong Liu; Chang Zhang; Zhen-Yu Zhang; Xiao-Ni Li; Zhen Zhang; Yin-Zheng Lin (Contributions to Mineralogy and Petrology, 2022)

Exploring the Risk Thresholds of Soil Heavy Metals in Carbonate and Non-carbonate Rock Areas: The Case of Qianjiang District in Chongqing, China - Xiang Wang; Xuezhen Li; Xiaozhen Zhou; Weikang Sheng; Kun Lin; Xudong Ma (Bulletin of Environmental Contamination and Toxicology, 2022)

Circular RNA expression profile of systemic lupus erythematosus and its clinical significance as a potential novel biomarker - Wenyu Li; Runge Fan; Cheng Zhou; Yue Wei; Shunsheng Lin; Sijian Wen; Wen Zeng; Wei Hou; Cheng Zhao; Youkun Lin (Genes & Genomics, 2022)
Background Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs that are more abundant, specific, and highly organized than linear RNAs. Increasing evidence supports that circRNAs may serve as diagnostic biomarkers in many diseases, but their potential as biomarkers in systemic lupus erythematosus (SLE) remains unclear. Objective We investigated the critical circRNAs involved in SLE progression and explored their potential application as biomarkers in SLE. Method RNA sequencing was conducted on peripheral blood mononuclear cells (PBMCs) from 4 SLE patients and 4 healthy volunteers. CircRNA profile data were analyzed to identify differentially expressed circRNAs and visualized via R software. After screening, qPCR analysis of target circRNA expression was performed using PBMCs from 31 SLE patients and 35 healthy volunteers. Correlations between circRNA expression levels and the SLEDAI score were assessed via Spearman correlation analysis. Finally, the performance of circRNAs as biomarkers in SLE was examined by receiver operating characteristic curve analysis. Results The result identified six differentially expressed circRNAs between SLE patients and healthy controls: hsa_circ_0006689, hsa_circ_0070562, hsa_circ_0006117, hsa_circ_0007683, hsa_circ_0042519, and hsa_circ_0008647. The validation analysis showed differing relative expression levels of hsa_circ_0007683, hsa_circ_0042519, hsa_circ_0008647, and hsa_circ_0006689 between SLE patients and healthy volunteers (P < 0.05), and hsa_circ_0006689 expression in PBMCs correlated with the SLEDAI score (P < 0.05). Furthermore, addition of hsa_circ_0006689 expression increased the sensitivities of anti-dsDNA antibody and anti-Sm antibody levels for SLE diagnosis (from 29.03 to 61.30% and 32.26–71.00%, respectively). Conclusion Our results suggest hsa_circ_0006689 may be a useful circRNA biomarker for SLE diagnosis and prognosis.

Genome sequence of the novel freshwater Microcystis cyanophage Mwe-Yong1112-1 - Ruqian Cai; Dengfeng Li; Wei Lin; Weinan Qin; Lingting Pan; Fei Wang; Minhua Qian; Wencai Liu; Qin Zhou; Chengxu Zhou; Yigang Tong (Archives of Virology, 2022)

Theoretical analysis on influence factors of anchor cable internal force under over-excavation considering earth berm - Jiayong Lin; Feicong Zhou; Wenhao Fan; Mao Chen; Jinyi Li; Yifan Jiang; Ming Lin; Ping Zhou; Zhijie Wang (Arabian Journal of Geosciences, 2022)

Surfactin isoforms isolated from a mushroom derived Bacillus halotolerans DMG-7-2 - Guo-Feng Zhou; Lin Yang; Shu-Hua Zhang; Yi Wang; Yu Yang; Rui Xu; Xue Zhao; Dan Nie; Junjie Shan; Cheng-Bin Cui; Chang-Wei Li (Natural Product Research, 2022)

Identification of serum metabolites enhancing inflammatory responses in COVID-19 - Chen-Song Zhang; Bingchang Zhang; Mengqi Li; Xiaoyan Wei; Kai Gong; Zhiyong Li; Xiangyang Yao; Jianfeng Wu; Cixiong Zhang; Mingxia Zhu; Lei Zhang; Xiufeng Sun; et al. (Science China Life Sciences, 2022)

Petrogenesis and tectonic setting of Early Silurian island-arc-type quartz diorite at the southern margin of the East Kunlun orogenic belt: analysis of the evolution of the Proto-Tethyan Ocean - Zuochen Li; Xianzhi Pei; Ruibao Li; Paul D. Bons; Lei Pei; Youxin Chen; Chengjun Liu; Meng Wang; Shaowei Zhao; Guochao Chen; Hai Zhou; Jie Zhao; et al. (International Journal of Earth Sciences, 2022)

The full-length genome sequence of a novel amalgavirus in Lilium spp. in China - Yanyan Huo; Xiaoting Li; Jiale Zhou; Shengjie Lin; Jiahao Ding; Huan Liu; Jianglian Yu; Ni Hong; Guoping Wang; Fang Ding (Archives of Virology, 2022)

Streptomyces akebiae sp. nov., a novel actinomycete isolated from rhizosphere soil of Akebia trifoliate - Ping Mo; Kaiqin Li; Jinhua Zhou; Fumin Zhou; Yazhi Chen; Xiaojia Lin; Xiaoyu Liu; Kerui Huang; Wansheng Zou; Jian Gao (Antonie van Leeuwenhoek, 2022)

The Super-large Ensemble Experiments of CAS FGOALS-g3 - Pengfei Lin; Bowen Zhao; Jilin Wei; Hailong Liu; Wenxia Zhang; Xiaolong Chen; Jie Jiang; Mengrong Ding; Wenmin Man; Jinrong Jiang; Xu Zhang; Yuewen Ding; et al. (Advances in Atmospheric Sciences, 2022)
A super-large ensemble simulation dataset with 110 members has been produced by the fully coupled model FGOALS-g3 developed by researchers at the Institute of Atmospheric Physics, Chinese Academy of Sciences. This is the first dataset of large ensemble simulations with a climate system model developed by a Chinese modeling center. The simulation has the largest realizations up to now worldwide in terms of single-model initial-condition large ensembles. Each member includes a historical experiment (1850–2014) and an experiment (2015–99) under the very high greenhouse gas emissions Shared Socioeconomic Pathway scenario (SSP5-8.5). The dataset includes monthly and daily temperature, precipitation, and other variables, requiring storage of 275 TB. Additionally, the surface air temperature (SAT) and land precipitation simulated by the FGOALS-g3 super-large ensemble have been validated and projected. The ensemble can capture the response of SAT and land precipitation to external forcings well, and the internal variabilities can be quantified. The availability of more than 100 realizations will help researchers to study rare events and improve the understanding of the impact of internal variability on forced climate changes.

Immune responses to Vibrio vulnificus formalin‐killed vaccine and ghost vaccine in Scophthalmus maximus - Shun Zhou; Ying Li; Jingyuan Yi; Xujia Zheng; Qing Huang; Lin Su; Baoshan Guo; Zongrui Yang; Yunji Xiu (Journal of Fish Diseases, 2022)
In this research, Vibrio vulnificus formalin‐killed (FKCs) vaccine and ghost (VVGs) vaccine were successfully developed, and shown to prevent vibriosis of Scophthalmus maximus resulting from V. vulnificus. The antibody titre of FKCs and VVGs vaccine was 1: 2 8 and 1: 2 11 . The RPS of FKCs and VVGs vaccine was 60% and 80%. In order to improve the understanding of vaccine protection mechanism, transcriptome data was used to analyse the immune response of S. maximus infected with V. vulnificus after vaccination with FKCs and VVGs vaccine. In the SmCon and SmIV groups, a series of innate immune‐related genes were upregulated (such as, TLR5, Tp12, AP‐1 and IL‐1β) or downregulated (such as, CASP6 and CASP8), which suggested that the immune protection mechanism induced by inactivated vaccine was similar to that of autoimmune response. In the SmIV and SmGho group, a number of innate and adaptive immune‐related genes (such as, STAT1, IFN‐γ and MHC Ia) were activated, in which the expression of these genes was higher in SmGho, and VVGs vaccine induced stronger innate and acquired immune responses. In conclusion, the results lay a foundation for further study on the molecular mechanisms of immune protection induced by VVGs vaccine and FKCs vaccine.

Effect modification by aging on the associations of nicotine exposure with cognitive impairment among Chinese elderly - Jian Hou; Chao Huang; Bo Zhu; Wei Liu; Qing-qing Zhu; Lu Wang; Tian Li; Chun-jie Yuan; Shao-yang Lai; De-sheng Wu; Fei-qi Zhu; Jia-fei Zhang; et al. (Environmental Science and Pollution Research, 2022)

Bioremediation of quinclorac injury on tobacco by a rhizosphere bacterium - Linhan Li; Ting Zhou; Linyu Zhong; Qian Zhou; Gang Gu; Mengjun Hu; Fengping Chen; Sheng Lin (World Journal of Microbiology and Biotechnology, 2022)

Source variation and tempo-spatial characteristics of health risks of heavy metals in surface dust in Beijing, China - Leiping Cao; Ruimin Liu; Yiling Zhou; Cong Men; Lin Li (Stochastic Environmental Research and Risk Assessment, 2022)

Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia - Kang-Wei Qian; Yun-Yun Li; Xiao-Hua Wu; Xue Gong; Ai-Lin Liu; Wen-Hao Chen; Zhe Yang; Ling-Jie Cui; Yun-Feng Liu; Yuan-Yuan Ma; Chen-Xi Yu; Furong Huang; et al. (Neuroscience Bulletin, 2022)

The different effects of intramuscularly-injected lactate on white and brown adipose tissue in vivo - Yaqian Qu; Siyu Chen; Lei Zhou; Min Chen; Lin Li; Yihan Ni; Jingquan Sun (Molecular Biology Reports, 2022)

Effects of regular addition and discontinuation of biosurfactant on hydrocarbon biodegradation and microorganisms in heavy oily sludge - Hanghai Zhou; Shichen Li; Lijia Jiang; Feng Zeng; Xiaoyun Lin; Chunlei Chen; Yanhong Li; Chunfang Zhang (Journal of Soils and Sediments, 2022)

Correction to: Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2022)

Chromosomal mapping of a locus associated with adult-stage resistance to powdery mildew from Agropyron cristatum chromosome 6PL in wheat - Yida Lin; Shenghui Zhou; Xuezhong Liang; Baojin Guo; Bing Han; Haiming Han; Jingpeng Zhang; Yuqing Lu; Zhi Zhang; Xinming Yang; Xiuquan Li; Weihua Liu; et al. (Theoretical and Applied Genetics, 2022)

CREB1 contributes colorectal cancer cell plasticity by regulating lncRNA CCAT1 and NF-κB pathways - Bin Li; Lisi Zheng; Jiayi Ye; Chenmin Zhang; Jie Zhou; Qiaojuan Huang; Yanhua Guo; Luqin Wang; Peng Yu; Shurong Liu; Qiao Lin; Yuxia Luo; et al. (Science China Life Sciences, 2022)

Estimating litchi flower number using a multicolumn convolutional neural network based on a density map - Jiaquan Lin; Jun Li; Zhou Yang; Huazhong Lu; Yunhe Ding; Huajun Cui (Precision Agriculture, 2022)

Activation of the TREK-1 Potassium Channel Improved Cognitive Deficits in a Mouse Model of Alzheimer’s Disease by Modulating Glutamate Metabolism - Fang Li; Shu-ning Zhou; Xin Zeng; Zhen Li; Rui Yang; Xue-xi Wang; Bin Meng; Wei-lin Pei; Li Lu (Molecular Neurobiology, 2022)

Transport process and mechanism of the Hongshiyan rock avalanche triggered by the 2014 Ludian earthquake, China - Shi-lin Zhang; Yue-ping Yin; Hai-bo Li; Wen-pei Wang; Jia-wen Zhou (Landslides, 2022)

Effectively compound the heterojunction formed by flower-like Bi2S3 and g-C3N4 to enhance photocatalytic activity - Yunmeng Cao; Lin Yue; Zhuang He; Zaixing Li; Jing Lian; Shilei Zhou; Xiao Luo (Environmental Science and Pollution Research, 2022)

Indirect effect of diabatic heating on Mei-yu frontogenesis - Yang Hu; Yi Deng; Yanluan Lin; Zhimin Zhou; Chunguang Cui; Chao Li; Xiquan Dong (Climate Dynamics, 2022)

Nematicidal activity of volatile organic compounds produced by Bacillus altitudinis AMCC 1040 against Meloidogyne incognita - Lin Ye; Jian-Yu Wang; Xiao-Fang Liu; Qi Guan; Nong-Xiao Dou; Jian Li; Qian Zhang; Yan-Ming Gao; Min Wang; Jian-She Li; Bo Zhou (Archives of Microbiology, 2022)

A Novel Preparation Method for Effervescent Tablets of Xianganfang Containing Fresh Juice using a Semi-Solid Extrusion 3D Printer with Three Cartridge Holders - Xiangru Dong; Wenfang Zhang; Xiaoting Wang; Sijia Liu; Jiawei Liang; Chunqiao Liufu; Shaofeng Zeng; Jiali Pang; Siting Li; Lingjuan Xiong; Guoyan Zhou; Weixing Zhu; et al. (AAPS PharmSciTech, 2022)

Loss of anthocyanidin synthase gene is associated with white flowers of Salvia miltiorrhiza Bge. f. alba, a natural variant of S. miltiorrhiza - Caicai Lin; Piyi Xing; Hua Jin; Changhao Zhou; Xingfeng Li; Zhenqiao Song (Planta, 2022)

Effects of pre-oxidation by ozone, permanganate and ferrate on generation and toxicities of disinfection byproducts - Y. Lin; Y. Lou; A. Li; Y. Wei; H. Li; M. Zhou; Y. Li (International Journal of Environmental Science and Technology, 2022)

Production and Evaluation of a Novel Multi-Epitope Bivalent Vaccine Against Echinococcus multilocaularis Metacestode - Runle Li; Mingyuan Xin; Kunmei Liu; Bingwen Hu; Jingwei Ma; Pei Zhou; Lin Feng; Mingquan Pang; Ri-li Ge; Haining Fan; Le Guo; Feng Tang (International Journal of Peptide Research and Therapeutics, 2022)

Genetic Diversity Evaluation and Population Structure Analysis of Red Swamp Crayfish (Procambarus clarkii) from Lakes and Rice Fields by SSR Markers - Xin-Fen Guo; Min Liu; Yu-Lin Zhou; Wen-Yu Wei; Zhi Li; Li Zhou; Zhong-Wei Wang; Jian-Fang Gui (Fishes, 2022)
The red swamp crayfish (Procambarus clarkii) is an important aquatic animal and has developed as a popular aquaculture species in China. In this study, a total of 72,839 SSR motifs were identified from transcriptional data, and 20 microsatellite markers of them were finally developed to assess the genetic diversities of seven wild populations from natural lakes and nine cultured populations from rice fields. Genetic diversity was slightly higher in the cultured populations than in the wild populations. The degree of genetic differentiation between cultured populations is slight, while a moderate to a large degree of genetic differentiation between wild populations and most of the variations occurred within individuals (79%). The analysis of cluster, principal coordinate analysis and STRUCTURE were similar, and they showed that isolation-by-distance pattern was not significant. The microsatellite markers developed in this study can not only be used for genetic monitoring of population but also provide important information for the management of breeding and cultured population in red swamp crayfish.

H3K4me3 CUT&Tag and Transcriptome Analysis Reveal the Epigenetic Regulatory Landscape in Gill Tissue of Large Yellow Croaker (Larimichthys crocea) Under Low Salinity Stress - Jian Yang; Minhai Liu; Weiliang Shen; Tingting Zhou; Xiongfei Wu; Qi Li; Zhihua Lin (Frontiers in Marine Science, 2022)
H3K4me3 is an important histone modification that could influence DNA replication and RNA translation in response to abiotic stress. Here, RNA-seq analyses were conducted in gill tissues of large yellow croaker to identify the function of H3K4me3 under low salinity stress. Additionally, CUT&Tag analyses were performed to identify the genome-wide dynamic changes in H3K4me3 and explore the mechanisms by which H3K4me3 regulates gene expression. A total of 201 differentially expressed genes (DEGs) were identified between the 5‰ low salinity group (S-group) and 25‰ normal salinity group (C-group), among which 23 DEGs (11 up-regulated H3K4me3 targets and 12 down-regulated targets) were directly regulated by H3K4me3. Our findings thus describe the epigenetic regulatory landscape of H3K4me3 in gill of large yellow croaker during low salinity stress, and provide novel insights into the regulation mechanisms of H3K4me3 mediating the responses of aquatic animals to abiotic stress.

Ar-plasma enhanced copper-nickel alloy catalysis for ammonia synthesis - Zhou Yimeng; Lv Jiabao; Peng Yaqi; Lin Xiaoqing; Lv Xingjie; Ye Qiulin; Liu Shaojun; Wu Angjian; Li Xiaodong (Waste Disposal & Sustainable Energy, 2022)

Sandstorms cause shrinkage of Haloxylon ammodendron shrubs and limit their self-renewal - Sheng-bo Shi; Dang-wei Zhou; Fang-lin Wang; Rui Shi; Tao Sun; Tian-cai Li; Jia-lin Ma; Xiang Wan; Jian-ping Ma; Jing-nian Tang (Theoretical and Experimental Plant Physiology, 2022)
Haloxylon ammodendron is an excellent windproof and sand-fixing species whose shrubs are widely cultivated in arid desert areas of northwest China but are now at risk of degradation and shrinkage. Using the chlorophyll fluorescence image analysis technique, the response of photosystem II (PSII) photochemical efficiency and non-photochemical quenching capacity to sediment-carrying wind and sand-free wind (both 12 m s −1 ) lasting for 10, 20, and 40 min were studied with seedlings in a wind tunnel. The results indicated that the sand-free wind had little influence on the maximum quantum efficiency of PSII photochemistry, F v / F m , which was approximately 0.80 on average; however, the F v / F m decreased over exposure time in the sediment-carrying wind group, with values smaller than those in the wind-only group. The non-photochemical quenching was sensitive to wind erosion, and sediment-carrying wind could aggravate the reduction in non-photochemical quenching ( NPQ ). Except for the 10 min duration, the maximum quantum efficiency of PSII photochemistry after dark recovery for 15 min, F v r / F m r , was lower in seedlings exposed to sediment-carrying wind than in those in the wind-only group. Compared to wind-only, wind-blown sand led to a water imbalance and withering in seedlings, causing the concentration of photosynthetic pigments (when based on the fresh mass of green branches) to not decrease. With a longer exposure time to sediment-carrying wind, both the probability and extent of lignified spots occurring increased in green assimilative branches. Our results demonstrated that sediment-carrying wind at 12 m s −1 lasting for 20 min or more could cause irreversible damage to the photosynthetic apparatus of H. ammodendron seedlings. Therefore, frequent and strong sandstorms are the main disturbance factors leading to shrinkage of shrubs and limiting their self-renewal.

Chaperone-mediated Autophagy Regulates Cell Growth by Targeting SMAD3 in Glioma - Hanqun Liu; Yuxuan Yong; Xingjian Li; Panghai Ye; Kai Tao; Guoyou Peng; Mingshu Mo; Wenyuan Guo; Xiang Chen; Yangfu Luo; Yuwan Lin; Jiewen Qiu; et al. (Neuroscience Bulletin, 2022)

SmGDB: genome database of Salvia miltiorrhiza, an important TCM Plant - Changhao Zhou; Caicai Lin; Piyi Xing; Xingfeng Li; Zhenqiao Song (Genes & Genomics, 2022)

Comparison of different inversion methods of D-T2 two-dimensional nuclear magnetic resonance logging and applicability analysis - Cheng-Lin Li; Mao-Jin Tan; Ke-Wen Wang; Feng Zhou; Ying-Ming Liu; Hai-Tao Zhang; Li-Zhi Xiao (Applied Geophysics, 2022)

Functional differentiation and complementation of alkaline phosphatases and choreography of DOP scavenging in a marine diatom - Kaidian Zhang; Jiashun Li; Jierui Wang; Xin Lin; Ling Li; Yanchun You; Xiaomei Wu; Zhi Zhou; Senjie Lin (Molecular Ecology, 2022)
Facing phosphate deficiency, phytoplankton use alkaline phosphatase (AP) to scavenge dissolved organophosphate (DOP). AP is a multitype (e.g., PhoA, PhoD) family of hydrolases and is known as a promiscuous enzyme with broad DOP substrate compatibility. Yet, whether the multiple types differentiate on substrates and collaborate to provide physiological flexibility remain elusive. Here we identify PhoA and PhoDs and document the functional differentiation between PhoA and a PhoD (PhoD_45757) in Phaeodactylum tricornutum . CRISPR/Cas9‐based mutations and physiological analyses reveal that (1) PhoA is a secreted enzyme and contributes the majority of total AP activity whereas PhoD_45757 is intracellular and contributes a minor fraction of the total AP activity, (2) AP gene expression compensates for each other after one is disrupted, (3) the DOP→PhoA→phosphate_uptake and the DOP_uptake→PhoD→phosphate pathways function interchangeably for some DOP substrates. These findings shed light on the underpinning of AP’s multiformity and have important implications in phytoplankton phosphorus‐nutrient niche differentiation, physiological plasticity, and competitive strategy.

Optimization of aquaculture sustainability through ecological intensification in China - Shuang‐lin Dong; Yun‐wei Dong; Ling Cao; Johan Verreth; Yngvar Olsen; Wen‐jing Liu; Qi‐zhi Fang; Yan‐gen Zhou; Li Li; Jing‐yu Li; Yong‐tong Mu; Patrick Sorgeloos (Reviews in Aquaculture, 2022)
As the world's leading producer of farmed aquatic food products, China faces great uncertainty concerning the further sustainable development of its aquaculture industry due to high and increasing pressure from environmental and resource constraints. To realize truly sustainable development, it is imperative to establish an evaluation system that integrates social, economic, environmental and resource criteria, and optimizes aquaculture systems through a holistic approach. Here, we used analytical hierarchy processes combined with expert judgment and objective data to assess the sustainability of 10 major aquaculture production systems (APSs) in China. Based on the evaluation results, we propose the ecological intensification of aquaculture systems (ELIAS), rationally integrating anthropogenic inputs with aquaculture ecosystem services, to improve the sustainability of APSs. The holistic evaluation system and ELIAS are fundamental and critical for the future development of aquaculture in China and globally.

Cover Image, Volume 14, Issue 3 - Shuang‐lin Dong; Yun‐wei Dong; Ling Cao; Johan Verreth; Yngvar Olsen; Wen‐jing Liu; Qi‐zhi Fang; Yan‐gen Zhou; Li Li; Jing‐yu Li; Yong‐tong Mu; Patrick Sorgeloos (Reviews in Aquaculture, 2022)
The cover image is based on the Review Article Optimization of aquaculture sustainability through ecological intensification in China by Shuang‐lin Dong et al., https://doi.org/10.1111/raq.12648 image

Massive Heat Shock Protein 70 Genes Expansion and Transcriptional Signatures Uncover Hard Clam Adaptations to Heat and Hypoxia - Zhi Hu; Hao Song; Jie Feng; Cong Zhou; Mei-Jie Yang; Pu Shi; Zheng-Lin Yu; Yong-Ren Li; Yong-Jun Guo; Hai-Zhou Li; Tao Zhang (Frontiers in Marine Science, 2022)
Heat shock protein 70 (HSP70) members participate in a wide range of housekeeping and stress-related activities in eukaryotic cells. In marine ecosystems, bivalves encounter abiotic stresses, including high temperatures and low dissolved oxygen. Here, 133 MmHSP70 genes were identified through combined methods including Blastp, HMM and manual filtration, based on the whole Mercenaria mercenaria genome. The MmHSP70 genes were unevenly distributed, and 41 genes (33.08%) were located on Chr 7. Phylogenetic analyses indicated that the MmHSP70 gene family mainly consisted of two clusters and the Hspa12 subfamily underwent lineage-specific expansion. A high-density collinear gene block was observed between M. mercenaria Chr 7 and Cyclina sinensis Chr 14. Tandem duplication MmHSP70 gene pairs experienced different levels of purifying selection, which could be an important source of sequence and functional constraints. MmHSP70 genes showed tissue-specific and stress-specific expression. Most tandem duplication HSP70 gene pairs had high expression under hypoxia stress. HSP70 B2 tandem duplication gene pairs showed significantly increased expression under heat plus severe hypoxia stress. This study provided a comprehensive understanding of the MmHSP70 gene family in the M. mercenaria and laid a significant foundation for further studies on the functional characteristics of MmHSP70 genes during exposure to heat and hypoxia stress.

Secoiridoid glycosides from the fruits of Cornus officinalis - Xin Wang; Xiang-Jian Zhong; Na Zhou; Lin-Lin Ji; Jin-Jie Li; Ning Cai; Qing-Bo Wang; Peng-Cheng Lin; Xiao-Ya Shang (Natural Product Research, 2022)

The genes for sensory perception of sound should be considered in gene diagnosis of congenital sensorineural hearing loss and microtia - Ken Lin; Ding-Yun You; Li-Huan Zhang; Li-Juan Zhou; Jin-Yan Zu; Yang Xiao; Mei-Hua Sun; Dong-Su; Xue Cao; Tie-Song Zhang; Jing Ma (Journal of Applied Genetics, 2022)

Study on pressure arch effect of xigeda strata tunnel based on experiment and discrete element simulation - Ping Zhou; Yifan Jiang; Feicong Zhou; Jinyi Li; Ming Lin; Jiayong Lin; Zhijie Wang (Bulletin of Engineering Geology and the Environment, 2022)

The Macrophage IL-23/IL-17A Pathway: A New Neuro-Immune Mechanism in Female Mechanical Pain - Zhi Tan; Zhen-Jia Lin; Long-Jun Wu; Li-Jun Zhou (Neuroscience Bulletin, 2022)

Follicular Fluid-Derived Exosomal MicroRNA-18b-5p Regulates PTEN-Mediated PI3K/Akt/mTOR Signaling Pathway to Inhibit Polycystic Ovary Syndrome Development - Zhi Zhou; Zhihua Tu; Juan Zhang; Can tan; Xiaoyong Shen; Bangbei Wan; Yejuan Li; Anguo Wang; Liqiang Zhao; Jiajia Hu; Ning Ma; Jing Zhou; et al. (Molecular Neurobiology, 2022)

IgE Reactivity of Potential Allergens from the Swimming Crab Portunus trituberculatus and the Research of ELISA Reagent for Detecting Crab Food Anaphylaxis - Xueni Qiu; Qiongyan Zhou; Xiaoxia Zhu; Wei Lin; Changkao Mu; Ronghua Li; Yangfang Ye; Weiwei Song; Ce Shi; Lei Liu; Huan Wang; Chunlin Wang; et al. (Journal of Ocean University of China, 2022)

Sterols and triterpenoids from Ganoderma lucidum and their reversal activities of tumor multidrug resistance - Min Wu; Cui-e Shen; Qiao-fa Lin; Jin-yi Zhong; Yan-fei Zhou; Ben-chen Liu; Jian-hua Xu; Zhi-qiang Zhang; Peng Li (Natural Product Research, 2022)

Extensive sequence divergence between the reference genomes of Taraxacum kok-saghyz and Taraxacum mongolicum - Tao Lin; Xia Xu; Huilong Du; Xiuli Fan; Qingwen Chen; Chunyan Hai; Zijian Zhou; Xiao Su; Liquan Kou; Qiang Gao; Lingwei Deng; Jinsheng Jiang; et al. (Science China Life Sciences, 2022)

Associations of CXCL12 polymorphisms with clinicopathological features in breast cancer: a case-control study - Shuai Lin; Yi Zheng; Meng Wang; Linghui Zhou; Yuyao Zhu; Yujiao Deng; Ying Wu; Dai Zhang; Na Li; Huafeng Kang; Zhijun Dai (Molecular Biology Reports, 2022)
Background Previous studies suggested that CXCL12 was involved in the development, metastasis, and invasion of breast cancer, and genetic variants were associated with the diagnosis and prognosis of patients with breast cancer. The present study was aimed to assess the relationships between CXCL12 polymorphisms (rs1801157, rs2297630, and rs2839693) and susceptibility and clinicopathological features of breast cancer. Methods A case-control study was conducted in 434 breast cancer patients and 450 health controls. Student t -test and chi-square test were used to analyze the differences of age distribution and genotype frequencies between the two groups. Correlations between polymorphisms and clinical parameters were also assessed by chi-square test. The potential effects of the three polymorphisms on CXCL12 were investigated by the public database. Results A statistical association was found between CXCL12 rs1801157 polymorphism and breast cancer risk, possibility of metastasis, and estrogen receptor status. Patients with rs2839693 C/T or C/T-T/T genotypes were more likely to be progesterone receptor-negative. However, no associations of rs2297630 polymorphism with breast cancer risk or any clinicopathological characteristics were observed. In addition, rs2297630 affected the splicing quantitative trait loci of CXCL12 in the subcutaneous fat, rs2839693 polymorphism affected the splicing quantitative trait loci of CXCL12 in the human breast mammary tissues. Conclusions Those results indicated that CXCL12 polymorphisms might be potential diagnostic indicators, and more investigation is needed in the future.

COX-2/PGE2 Pathway Inhibits the Ferroptosis Induced by Cerebral Ischemia Reperfusion - Yunfei Xu; Ying Liu; Kexin Li; Dun Yuan; Shun Yang; Lin Zhou; Yao Zhao; Shuying Miao; Caihong Lv; Jie Zhao (Molecular Neurobiology, 2022)

Hemorrhage-Induced Sphingosine Kinase 1 Contributes to Ferroptosis-Mediated Secondary Brain Injury in Intracerebral Hemorrhage - Xiaojun Diao; Qi Cui; Ning Tian; Zixian Zhou; Wenjing Xiang; Yanlin Jiang; Jungang Deng; Hongzhan Liao; Xiaohui Lin; Qinghua Li; Rujia Liao (Molecular Neurobiology, 2022)

Establishment of Galectin-3 Time-resolved Fluoroimmunoassay and its Application in Idiopathic Membranous Nephropathy - Xiaomei Yu; Lingli Chen; Bo Lin; Li Zhang; Xue Yang; Xiaobin Liu; Pengguo Xia; Yueming Liu; Shaoxiong Zheng; Xiumei Zhou; Yigang Wang; Yuan Qin; et al. (Journal of Fluorescence, 2022)

Exogenous ascorbic acid application alleviates cadmium toxicity in seedlings of two wheat (Triticum aestivum L.) varieties by reducing cadmium uptake and enhancing antioxidative capacity - Zhen Zhou; Chang Wei; Haitao Liu; Qiujuan Jiao; Gezi Li; Jingjing Zhang; Biao Zhang; Weihuan Jin; Di Lin; Guo Chen; Suqin Yang (Environmental Science and Pollution Research, 2022)

Fine mapping of the tiller inhibition gene TIN4 contributing to ideal plant architecture in common wheat - Zhiqiang Wang; Fangkun Wu; Xudong Chen; Wanlin Zhou; Haoran Shi; Yu Lin; Shuai Hou; Shifan Yu; Hong Zhou; Caixia Li; Yaxi Liu (Theoretical and Applied Genetics, 2022)

Interferon-induced transmembrane protein 2 promotes epithelial-mesenchymal transition by activating transforming growth factor-β1/small mother against decapentaplegic 2 signaling in gastric cancer - Yonggang Liu; Minyu Zhou; Jianhua Wu; Zhaowei Wen; Yisheng Fang; Li Lin; Meihua Luo; Li Sun; Wangjun Liao (Molecular Biology Reports, 2022)

Upregulation of h-TERT and Ki-67 in ectopic endometrium is associated with recurrence of endometriosis - Jie Luo; Zhimin Song; Tao Zhang; Ketan Chu; Jingyi Li; Jianhong Zhou; Jun Lin (Journal of Zhejiang University-SCIENCE B, 2022)

Video target detection of East Asian migratory locust based on the MOG2-YOLOv4 network - Zhao Bai; Zhan Tang; Lei Diao; Shuhan Lu; Xuchao Guo; Han Zhou; Chengqi Liu; Lin li (International Journal of Tropical Insect Science, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Different effects of the DRD4 genotype on intrinsic brain network connectivity strength in drug-naïve children with ADHD and healthy controls - Shuangli Chen; Andan Qian; Jiejie Tao; Ronghui Zhou; Chuqi Fu; Chuang Yang; Qingxia Lin; JieJie Zhou; Jiance Li; Xiaoqi Huang; Meihao Wang (Brain Imaging and Behavior, 2022)
The dopamine D4 receptor gene (DRD4) has been consistently reported to be associated with attention-deficit/hyperactivity disorder (ADHD). Recent studies have linked DRD4 to functional connectivity among specific brain regions. The current study aimed to compare the effects of the DRD4 genotype on functional integrity in drug-naïve ADHD children and healthy children. Resting-state functional MRI images were acquired from 49 children with ADHD and 37 healthy controls (HCs). We investigated the effects of the 2-repeat allele of DRD4 on brain network connectivity in both groups using a parameter called the degree of centrality (DC), which indexes local functional relationships across the entire brain connectome. A voxel-wise two-way ANCOVA was performed to examine the diagnosis-by-genotype interactions on DC maps. Significant diagnosis-by-genotype interactions with DC were found in the temporal lobe, including the left inferior temporal gyrus (ITG) and bilateral middle temporal gyrus (MTG) (GRF corrected at voxel level p < 0.001 and cluster level p < 0.05, two-tailed). With the further subdivision of the DC network according to anatomical distance, additional brain regions with significant interactions were found in the long-range DC network, including the left superior parietal gyrus (SPG) and right middle frontal gyrus (MFG). The post-hoc pairwise analysis found that altered network centrality related to DRD4 differed according to diagnostic status (p < 0.05). This genetic imaging study suggests that the DRD4 genotype regulates the functional integration of brain networks in children with ADHD and HCs differently. This may have important implications for our understanding of the role of DRD4 in altering functional connectivity in ADHD subjects.

Synthesis of Silver- and Strontium-Substituted Hydroxyapatite with Combined Osteogenic and Antibacterial Activities - Yunfei Li; Wenying Wang; Jing Han; Zirui Li; Qiuxiang Wang; Xue Lin; Kun Ge; Guoqiang Zhou (Biological Trace Element Research, 2022)

Natural forests promote phosphorus retention in soil - Zhen Yu; Zhou Guoyi; Lei Liu; Stefano Manzoni; Philippe Ciais; Daniel Goll; Josep Peñuelas; Jordi Sardans; Wantong Wang; Jie Zhu; Lin Li; Junhua Yan; et al. (Global Change Biology, 2022)
Soil phosphorus (P) availability often limits plant productivity. Classical theories suggest that total P content declines at the temporal scale of pedogenesis, and ecosystems develop toward the efficient use of scarce P during succession. However, the trajectory of ecosystem P within shorter time scales of succession remains unclear. We analyzed changes to P pools at the early (I), middle (II), and late (III) stages of growth of plantation forests (PFs) and the successional stages of natural forests (NFs) at 1969 sites in China. We found significantly lower P contents at later growth stages compared to earlier ones in the PF ( p p

The role of social networks in relocation induced by climate-related hazards: an empirical investigation in China - Jing Tan; Kui Zhou; Li Peng; Lei Lin (Climate and Development, 2022)

Effect of Sodium Salicylate on Calcium Currents and Exocytosis in Cochlear Inner Hair Cells: Implications for Tinnitus Generation - Ting Fan; Meng-Ya Xiang; Ruo-Qiao Zhou; Wen Li; Li-Qin Wang; Peng-Fei Guan; Geng-Lin Li; Yun-Feng Wang; Jian Li (Neuroscience Bulletin, 2022)

The frequency of cannibalism by Spodoptera frugiperda larvae determines their probability of surviving food deprivation - Hualiang He; Ailin Zhou; Li He; Lin Qiu; Wenbing Ding; Youzhi Li (Journal of Pest Science, 2022)

Di(2-ethylhexyl) phthalate (DEHP) and thyroid: biological mechanisms of interference and possible clinical implications - Xueting Zhang; Wen Qi; Qi Xu; Xu Li; Liting Zhou; Lin Ye (Environmental Science and Pollution Research, 2022)

Performance and mechanisms of fly ash for graphene oxide removal from aqueous solution - Ping Jiang; Lin Zhou; Wei Wang; Na Li; Fang Zhang (Environmental Science and Pollution Research, 2022)

Molecular Mechanism of Aluminum-Induced Oxidative Damage and Apoptosis in Rat Cardiomyocytes - LiuFang Zhou; Mingjie He; XiaoLan Li; Erbing Lin; YingChuan Wang; Hua Wei; Xi Wei (Biological Trace Element Research, 2022)

Inhibition of FOSL2 aggravates the apoptosis of ovarian cancer cells by promoting the formation of inflammasomes - Jie Li; Li Zhou; Hongye Jiang; Lin Lin; Yinguang Li (Genes & Genomics, 2022)
Background Ovarian cancer is a common gynecological malignancy among female patients and poses a serious threat to women’s health. Although it has been established that Fos-like antigen 2 (FOSL2) is linked to ovarian cancer (OC), its exact role in the development of OC remains unknown. Objective This article aims to investigate the role of FOSL2 in ovarian cancer development. Methods FOSL2 expression in ovarian carcinoma and adjacent tissues was assessed using real-time fluorescent quantitative PCR and western blot. We constructed OE/sh-FOSL2 plasmids and Caspase-1 specific inhibitors (Yvad-CMK) and transfected A 2780 cells with them to identify the relevant cell functions. Furthermore, we used western blot assay to determine the changes in expression of apoptosis-associated speck-like protein containing a CARD (ASC), cysteine aspartate-specific proteasezymogen procaspase 1 (pro-caspase-1), cysteinyl aspartate-specific proteinase-1 (caspase-1), interleukin-1β precursor (pro-IL-1β), interleukin-1β (IL-1β), interleukin-18 precursor (pro-IL-18), and interleukin-18 (IL-18). In addition, we measured the concentration of IL-1β and IL-18 using an enzyme-linked immunosorbent assay (ELISA). Moreover, Tthe level of lactate dehydrogenase (LDH) in the cell supernatant was measured by LDH release assay kit. Results The expression of FOSL2 was significantly higher compared with the surrounding tissues. The proliferation, migration, and invasion of A2780 cells were enhanced after transfection with OE-FOSL2 plasmids; however, the cell apoptosis was significantly decreased. When FOSL2 was overexpressed, the inflammasome-associated proteins such as ASC, caspase-1, IL-1β, and IL-18 were downregulated. Furthermore, FOSL2 induced apoptosis and activated the production of inflammasomes in A2780 cells. Co-therapy with Yvad-CMK and substantially inhibited apoptosis and activation of inflammasomes. Conclusions Inhibition of FOSL2 promotes the apoptosis of OC cells by mediating the formation of an inflammasome.

An innovative echo detection system with STM32 gated and PMT adjustable gain for airborne LiDAR - Guoqing Zhou; Weihao Li; Xiang Zhou; Yizhi Tan; Gangchao Lin; Xianxing Li; Ronghua Deng (International Journal of Remote Sensing, 2021)

Antioxidant CPA-type indole alkaloids produced from the deep-sea derived fungus Aspergillus sp. SCSIO 41024 - Wei-Hao Chen; Kun-Long Li; Xiu-Ping Lin; Sheng-Rong Liao; Bin Yang; Xue-Feng Zhou; Jun-Jian Wang; Yong-Hong Liu; Jun-Feng Wang (Natural Product Research, 2021)

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2021)

Evolutionary characteristics and phylogeny of cotton chloroplast tRNAs - Ning Wang; Wan-Lin Dong; Xiao-Jing Zhang; Tong Zhou; Xiao-Juan Huang; Bao-Guo Li; Jian-Ni Liu; Xiong-Feng Ma; Zhong-Hu Li (Planta, 2021)

Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling - Yirong Chen; Renye Que; Na Zhang; Liubing Lin; Mengen Zhou; Yong Li (Molecular Biology Reports, 2021)
Background Hepatic fibrosis is the final pathway of chronic liver disease characterized by excessive accumulation of extracellular matrix (ECM), which eventually develop into cirrhosis and liver cancer. Emerging studies demonstrated that Saikosaponin-d (SSd) exhibits a protective role in liver fibrosis. However, the mechanism underlying anti-liver fibrosis of SSd in vivo and in vitro remains unclear. Methods and results Transforming growth factor (TGF)-β and carbon tetrachloride (CCl 4 ) were used for creating liver fibrosis model in vitro and in vivo, respectively. The role of SSd in regulating liver fibrosis was assessed through Sirius red and Masson staining, and IHC assay. We found that SSd attenuated remarkably CCl 4 -induced liver fibrosis as evidenced by decreased collagen level, and decreased expression of fibrotic markers Col 1 and α-SMA. Meanwhile, SSd repressed autophagy activation as suggested by decreased BECN1 expression and increased p62 expression. Compared with HSCs from CCl 4 -treated group, the primary HSCs from SSd-treated mice exhibited a marked inactivation of autophagy. Mechanistically, SSd treatment enhanced the expression of GPER1 in primary HSCs and in TGF-β-treated LX-2 cells. GPER1 agonist G1 repressed autophagy activation, whereas GPER1 antagonist G15 activated autophagy and G15 also damaged the function of SSd on suppressing autophagy, leading to subsequent increased levels of fibrotic marker level in LX-2 cells. Conclusions Our findings highlight that SSd alleviates hepatic fibrosis by regulating GPER1/autophagy pathway.

Melatonin Reduces Neuroinflammation and Improves Axonal Hypomyelination by Modulating M1/M2 Microglia Polarization via JAK2-STAT3-Telomerase Pathway in Postnatal Rats Exposed to Lipopolysaccharide - Qiuping Zhou; Lanfen Lin; Haiyan Li; Huifang Wang; Shuqi Jiang; Peixian Huang; Qiongyu Lin; Xuan Chen; Yiyu Deng (Molecular Neurobiology, 2021)
Microglia activation and associated inflammation are implicated in the periventricular white matter damage (PWMD) in septic postnatal rats. This study investigated whether melatonin would mitigate inflammation and alleviate the axonal hypomyelination in the corpus callosum in septic postnatal rats. We further explored if this might be related to the modulation of microglial polarization from M1 phenotype to M2 through the JAK2/STAT3/telomerase pathway. We reported here that indeed melatonin not only can it reduce the neurobehavioral disturbances in LPS-injected rats, but it can also dampen microglia-mediated inflammation. Thus, in LPS + melatonin group, the expression of proinflammatory mediators in M1 phenotype microglia was downregulated. As opposed to this, M2 microglia were increased which was accompanied by upregulated expression of anti-inflammatory mediators along with telomerase reverse transcriptase or melatonin receptor 1(MT1). In parallel to this was decreased NG2 expression but increased expression of myelin and neurofilament proteins. Melatonin can improve hypomyelination which was confirmed by electron microscopy. In vitro in primary microglia stimulated by LPS, melatonin decreased the expression of proinflammatory mediators significantly; but it increased the expression of anti-inflammatory mediators. Additionally, the expression levels of p-JAK2 and p-STAT3 were significantly elevated in microglia after melatonin treatment. Remarkably, the effect of melatonin on LPS-treated microglia was blocked by melatonin receptor, JAK2, STAT3 and telomerase reverse transcriptase inhibitors, respectively. Taken together, it is concluded that melatonin can attenuate PWMD through shifting M1 microglia towards M2 via MT1/JAK2/STAT3/telomerase pathway. The results suggest a new therapeutic strategy whereby melatonin may be adopted to convert microglial polarization from M1 to M2 phenotype that would ultimately contribute to the attenuation of PWMD.

Histological alterations, oxidative stress, and inflammatory response in the liver of swamp eel (Monopterus albus) acutely exposed to copper - Lin Liu; Qiubai Zhou; Changgao Lin; Li He; Lili Wei (Fish Physiology and Biochemistry, 2021)

Occurrence, source apportionment, and carcinogenic risk assessment of polycyclic aromatic hydrocarbons in urban road dusts in Shanghai - Xue-Tong Wang; Rui Fu; Ying Zhou; Cheng-Lin Wang; Guo-Fa Ren; Xiao-Li Wang; Hui Li (Environmental Science and Pollution Research, 2021)

Long-term changes of water acidity in an intact forested watershed in south China - Xiao-dong Liu; Ying-jie Feng; Qi-feng Mo; Guo-wei Chu; Yue-lin Li; Qian-mei Zhang; Wei-qiang Zhang; Xian-hua Gan; Qing Zhou (Journal of Mountain Science, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Characterization and identification of SFDC ‐1, a novel AmpC ‐type β‐lactamase in Serratia fonticola - Xu Dong; Peiyao Zhang; Kexin Zhou; Jialei Liang; Qiaoling Li; Xueya Zhang; Danying Zhou; Wei Lu; Zhewei Sun; Hongmao Liu; Junwan Lu; Xi Lin; et al. (Environmental Microbiology, 2021)
Summary The clinical and environmental infections caused by AmpC β‐lactamases have been increasingly reported recently. In this study, we characterize the novel chromosome‐encoded AmpC β‐lactamase SFDC‐1 identified in Serratia fonticola strain R28, which was isolated from a rabbit raised on a farm in southern China. SFDC‐1 shared the highest amino acid identity of 79.6% with the functionally characterized AmpC β‐lactamase gene bla YRC‐1 , although it had highly homologous functionally uncharacterized relatives in the same species from different sources, including some of the clinical significance. The cloned bla SFDC‐1 exhibited resistance to a broad spectrum of β‐lactam antibiotics, including most cephalosporins with the highest resistance to ampicillin, cefazolin and ceftazidime, with increased MIC levels ≥128‐fold compared with the control strains. The purified SFDC‐1 showed catalytic activities against β‐lactams with the highest catalytic activity to cefazolin. The genetic context of bla SFDC‐1 and its relatives was conserved in the chromosome, and no mobile genetic elements were found surrounding them.

Rapid visual genotyping method for germline mutants with small genomic fragment deletion by allele-specific PCR and lateral flow nucleic acid biosensor - Qiuju Su; Xiang Zhou; Tianwen Wu; Kui Li; Wentao Xu; Zhenyu Lin; Ping Shen; Bang Liu (Molecular Biology Reports, 2021)

Spatiotemporal change of vegetation coverage recovery and its driving factors in the Wenchuan earthquake-hit areas - Xiao-fei Sun; Lin-guo Yuan; Ying-zhi Zhou; Huai-yong Shao; Xian-feng Li; Ping Zhong (Journal of Mountain Science, 2021)

Local community assembly processes shape β‐diversity of soil phoD ‐harbouring communities in the Northern Hemisphere steppes - Lin Xu; Nianpeng He; Xiangzhen Li; Huili Cao; Chaonan Li; Ruili Wang; Changhui Wang; Minjie Yao; Shungui Zhou; Junming Wang (Global Ecology and Biogeography, 2021)
Aim The contemporary coexistence theory suggests that species pool, environmental filtering, dispersal assembly processes, ecological drift and biotic interactions collectively determine the β‐diversity of communities. However, we know little about the biogeographical patterns of the β‐diversity of microbial communities harbouring the alkaline phosphatase phoD gene ( phoD communities, hereafter) and whether these mechanisms are all‐important in shaping phoD communities’ β‐diversity in natural steppe ecosystems. Location Northern Hemisphere steppes. Time period July to August 2018. Major taxa studied Alkaline phosphatase ( phoD gene) encoding community. Methods Using the high throughput amplicon sequencing method, soil phoD communities were comparatively studied along three representative regions of the Northern Hemisphere steppes, namely the Qinghai‐Tibetan Plateau, Inner Mongolian Plateau and the Loess Plateau. Each region harbours three types of steppes (habitats): meadow, typical and desert steppes. Results We observed significantly higher phoD β‐diversity in the Qinghai‐Tibetan than in the Loess and Inner Mongolian Plateaus and significantly lower β‐diversity in the typical steppes than in other steppe types. The decay rates of phoD β‐diversity with geographical distance varied in different steppe regions and types. The phoD β‐diversity was not significantly influenced by species pool; instead, environmental filtering, dispersal assembly processes, ecological drift and biotic interactions jointly shaped the β‐diversity patterns. The β‐deviation variations (β‐diversity excluding the effects of species pool) were influenced by spatial and environmental factors and biotic interactions, among which soil pH was the key environmental determinant. The soil pH driving β‐diversity mechanism was steppe region and habitat specific. Main conclusions The biogeographical patterns of phoD β‐diversity were mainly driven by local community assembly processes in the Northern Hemisphere steppes.

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Meta-analyses of maternal exposure to atmospheric particulate matter and risk of congenital anomalies in offspring - Guangxia Yu; Yao Chen; Jianping Tang; Zhifeng Lin; Fuli Zheng; Chunyan Zheng; Jinfu Zhou; Qianqian Su; Siying Wu; Huangyuan Li (Environmental Science and Pollution Research, 2021)

Added value of kilometer-scale modeling over the third pole region: a CORDEX-CPTP pilot study - Xu Zhou; Kun Yang; Lin Ouyang; Yan Wang; Yaozhi Jiang; Xin Li; Deliang Chen; Andreas Prein (Climate Dynamics, 2021)

Damage mechanism of tunnels in the high-content salt rock stratum - Ping Zhou; Jinyi Li; Yifan Jiang; Feicong Zhou; Ming Lin; Jiayong Lin; Zhijie Wang (Bulletin of Engineering Geology and the Environment, 2021)

Degraded polysaccharides from Porphyra haitanensis: purification, physico-chemical properties, antioxidant and immunomodulatory activities - Yun-Feng Huo; Yin-Ting Li; Wei Xia; Chong Wang; Yuan-Yuan Xie; Yan-Bo Wang; Tao Zhou; Ling-Lin Fu (Glycoconjugate Journal, 2021)

Ambient climate determines the directional trend of community stability under warming and grazing - Peipei Liu; Wangwang Lv; Jianping Sun; Caiyun Luo; Zhenhua Zhang; Xiaoxue Zhu; Xingwu Lin; Jichuang Duan; Guangping Xu; Xiaofeng Chang; Yigang Hu; Qiaoyan Lin; et al. (Global Change Biology, 2021)
Changes in ecological processes over time in ambient treatments are often larger than the responses to manipulative treatments in climate change experiments. However, the impacts of human‐driven environmental changes on the stability of natural grasslands have been typically assessed by comparing differences between manipulative plots and reference plots. Little is known about whether or how ambient climate regulates the effects of manipulative treatments and their underlying mechanisms. We collected two datasets, one a 36‐year long‐term observational dataset from 1983 to 2018, and the other a 10‐year manipulative asymmetric warming and grazing experiment using infrared heaters with moderate grazing from 2006 to 2015 in an alpine meadow on the Tibetan Plateau. The 36‐year observational dataset shows that there was a nonlinear response of community stability to ambient temperature with a positive relationship between them due to an increase in ambient temperature in the first 25 years and then a decrease in ambient temperature thereafter. Warming and grazing decreased community stability with experiment duration through an increase in legume cover and a decrease in species asynchrony, which was due to the decreasing background temperature through time during the 10‐year experiment period. Moreover, the temperature sensitivity of community stability was higher under the ambient treatment than under the manipulative treatments. Therefore, our results suggested that ambient climate may control the directional trend of community stability while manipulative treatments may determine the temperature sensitivity of the response of community stability to climate relative to the ambient treatment. Our study emphasizes the importance of the context dependency of the response of community stability to human‐driven environmental changes.

High-throughput sequencing clarifies the spatial structures of microbial communities in cadmium-polluted rice soils - Li Song; Zhenzhi Pan; Yi Dai; Lin Chen; Li Zhang; Qilin Liao; Xiezhi Yu; Hongyan Guo; Guisheng Zhou (Environmental Science and Pollution Research, 2021)

Future variation in mountainous discharge in arid northwestern China: A basin case study - Lei Wu; Chang-bin Li; Xu-hong Xie; Jia-nan Lv; Jian-mei Wei; Xuan Zhou; Lin-shan Yang (Journal of Mountain Science, 2021)

3D Step-by-step inversion strategy for audio magnetotellurics data based on unstructured mesh - San Cheng; Zhi-Yong Zhang; Feng Zhou; Man Li; Hui Chen; Fu-Sheng Shi; Lin-Pin Huang; Yong Li (Applied Geophysics, 2021)

Wogonin Accelerates Hematoma Clearance and Improves Neurological Outcome via the PPAR-γ Pathway After Intracerebral Hemorrhage - Jianfeng Zhuang; Yucong Peng; Chi Gu; Huihui Chen; Zheng Lin; Hang Zhou; Xiao Wu; Jianru Li; Xiaobo Yu; Yang Cao; Hanhai Zeng; Xiongjie Fu; et al. (Translational Stroke Research, 2021)

Whole brain volume and cortical thickness abnormalities in Wilson’s disease: a clinical correlation study - Yukun Song; Lin Zou; Jing Zhao; Xiangxue Zhou; Yingqian Huang; Haishan Qiu; Haiwei Han; Zhiyun Yang; Xunhua Li; Xiaoying Tang; Jianping Chu (Brain Imaging and Behavior, 2021)

Long‐term nitrogen input alters plant and soil bacterial, but not fungal beta diversity in a semiarid grassland - Weixing Liu; Lingli Liu; Xian Yang; Meifeng Deng; Zhou Wang; Pandeng Wang; Sen Yang; Ping Li; Ziyang Peng; Lu Yang; Lin Jiang (Global Change Biology, 2021)
Anthropogenic nitrogen (N) input is known to alter plant and microbial α‐diversity, but how N enrichment influences β‐diversity of plant and microbial communities remains poorly understood. Using a long‐term multilevel N addition experiment in a temperate steppe, we show that plant, soil bacterial and fungal communities exhibited different responses in their β‐diversity to N input. Plant β‐diversity decreased linearly as N addition increased, as a result of increased directional environmental filtering, where soil environmental properties largely explained variation in plant β‐diversity. Soil bacterial β‐diversity first increased then decreased with increasing N input, which was best explained by corresponding changes in soil environmental heterogeneity. Soil fungal β‐diversity, however, remained largely unchanged across the N gradient, with plant β‐diversity, soil environmental properties, and heterogeneity together explaining an insignificant fraction of variation in fungal β‐diversity, reflecting the importance of stochastic community assembly. Our study demonstrates the divergent effect of N enrichment on the assembly of plant, soil bacterial and fungal communities, emphasizing the need to examine closely associated fundamental components (i.e., plants and microorganisms) of ecosystems to gain a more complete understanding of ecological consequences of anthropogenic N enrichment.

Identification of potential sex-related genes in Siniperca chuatsi - Qiaoying Zhu; Chong Han; Cheng Peng; Xingni Zhou; Chongwei Wang; Linqiang Han; Shuisheng Li; Guifeng Li; Haoran Lin; Yong Zhang (Journal of Oceanology and Limnology, 2021)

Human papillomavirus prevalence among men who have sex with men in China: a systematic review and meta-analysis - Yiguo Zhou; Yi-Fan Lin; Lei Gao; Jianghong Dai; Ganfeng Luo; Lanying Li; Tanwei Yuan; Peiyang Li; Yuewei Zhan; Yanxiao Gao; Huachun Zou (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

N6-methyladenine DNA Demethylase ALKBH1 Regulates Mammalian Axon Regeneration - Qiao Li; Cheng Qian; Harry Feng; Tyger Lin; Qingsan Zhu; Ying Huang; Feng-Quan Zhou (Neuroscience Bulletin, 2021)

Serum macrophage migration inhibitory factor as a potential biomarker to evaluate therapeutic response in patients with allergic asthma: an exploratory study - Huiyuan Zhu; Shaochun Yan; Jingshuo Wu; Zhong Zhang; Xiaolin Li; Zheng Liu; Xing Ma; Lina Zhou; Lin Zhang; Mingming Feng; Yiwei Geng; Aixin Zhang; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Al-PHOSLOCK thin-layer capping to control phosphorus release from sediment: effect of hydraulic retention time and phosphorus migration/transformation mechanism - Canyang Lin; Shuwen Li; Bolin Zhu; Shupo Liu; Fei Li; Zhenming Zhou; Tao Li (Journal of Soils and Sediments, 2021)

Combining ability and genetic diversity under low-temperature conditions at germination stage of maize (Zea mays L.) - Jiayue Zhang; Yichen Li; Ziwen Zhang; Hong Di; Lin Zhang; Xuerui Wang; Zhenhua Wang; Yu Zhou (Euphytica, 2021)

Exposed to Mercury-Induced Oxidative Stress, Changes of Intestinal Microflora, and Association between them in Mice - Yulan Zhao; Changming Zhou; Xiaoquan Guo; Guoliang Hu; Guyue Li; Yu Zhuang; Huabin Cao; Lin Li; Chonghong Xing; Caiying Zhang; Fan Yang; Ping Liu (Biological Trace Element Research, 2021)

Study on characteristics of waterflooding in fractured reservoirs based on discrete fracture model - Fanle Meng; Junjian Li; Hanqiao Jiang; Lin Zhao; Linkai Li; Yan Qiao; Yu Zhou; Fei Xu (Arabian Journal of Geosciences, 2021)

Mortality burden caused by diurnal temperature range: a nationwide time-series study in 364 Chinese locations - Min Cai; Jianxiong Hu; Chunliang Zhou; Zhulin Hou; Yanjun Xu; Maigeng Zhou; Yize Xiao; Biao Huang; Xiaojun Xu; Lifeng Lin; Tao Liu; Jianpeng Xiao; et al. (Stochastic Environmental Research and Risk Assessment, 2021)

Structure of SARS-CoV-2 main protease in the apo state - Xuelan Zhou; Fanglin Zhong; Cheng Lin; Xiaohui Hu; Yan Zhang; Bing Xiong; Xiushan Yin; Jinheng Fu; Wei He; Jingjing Duan; Yang Fu; Huan Zhou; et al. (Science China Life Sciences, 2021)

Protein kinase PpCIPK1 modulates plant salt tolerance in Physcomitrella patens - Fei Xiao; Xiaochuan Li; Jiaxian He; Jinfeng Zhao; Guochun Wu; Qianyuan Gong; Huapeng Zhou; Honghui Lin (Plant Molecular Biology, 2021)

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

The effect of secondary capping on the control of phosphorus release from sediment by activated thin-layer capping with Al-PIA - Bolin Zhu; Shuwen Li; Canyang Lin; Shupo Liu; Fei Li; Zhenming Zhou (Environmental Science and Pollution Research, 2021)

Marinobacter shengliensis subsp. alexandrii Subsp. Nov., Isolated from Cultivable Phycosphere Microbiota of Highly Toxic Dinoflagellate Alexandrium catenella LZT09 and Description of Marinobacter shengliensis Subsp. shengliensis Subsp. Nov - Xi Yang; Rong Xiang; Nurhezreen Md Iqbal; Yu-Han Duan; Xiao-Ai Zhang; Lei Wang; Lin-Zeng Yu; Jia-Zhou Li; Ming-Fei Sun; Qiao Yang; Chun-Tian Zheng; Shen-Quan Liao (Current Microbiology, 2021)

Abberant inverted U-shaped brain pattern and trait-related retinal impairment in schizophrenia patients with combined auditory and visual hallucinations: a pilot study - Chuanjun Zhuo; Bo Xiao; Ce Chen; Deguo Jiang; Gongying Li; Xiaoyan Ma; Ranli Li; Lina Wang; Yong Xu; Chunhua Zhou; Xiaodong Lin (Brain Imaging and Behavior, 2021)
Schizophrenic patients often experience auditory hallucinations (AHs) and visual hallucinations (VHs). However, brain and retinal alterations associated with combined AHs and VHs in schizophrenic patients are unknown. This study aimed o investigate brain and retinal alterations in first episode un-treated schizophrenic patients with combined AHs and VHs (FUSCHAV). FUSCHAV patients ( n = 120), divided into four groups according to severity of AH and VH symptoms, were compared to healthy controls ( n = 30). Gray matter volume (GMV) and global functional connectivity density (gFCD) were recorded to reflect brain structure and functional alterations. Total retinal thickness was acquired by optical coherence tomography to assess retinal impairment. The majority of FUSCHAV patients (85.8%) demonstrated both GMV reduction and gFCD increases along with retinal thinning compared to healthy controls. The severity of GMV reduction and gFCD increase differed between patient groups, ranked from highest to lowest severity as follows: severe AHs combined with severe VHs (FUSCHSASV, 20 patients), moderate AHs combined with severe VHs (FUSCHMASV, 23 patients), severe AHs combined with moderate VHs (FUSCHSAMV, 28 patients), and moderate AHs combined with moderate VHs (FUSCHMAMV, 26). Retinal impairment was similar among the four FUSCHAV groups. GMV reduction and gFCD increases in the frontal-parietal lobule show an inverted U-shaped pattern among FUSCHAV patients according to AH and VH severity, while retinal impairment remains stable among FUSCHAV groups. These findings indicate a reciprocal deterioration in auditory and visual disturbances among FUSCHAV patients.

DNAH17 is essential for rat spermatogenesis and fertility - Liling Chen; Jiamin Ouyang; Xueqing Li; Xueshan Xiao; Wenmin Sun; Shiqiang Li; Lin Zhou; Yuandong Liao; Qingjiong Zhang (Journal of Genetics, 2021)

The molecular mechanism of a novel derivative of BTO-956 induced apoptosis in human myelomonocytic lymphoma cells - Yu-Lin Li; De-Jun Zhou; Zheng-Guo Cui; Lu Sun; Qian-Wen Feng; Shahbaz Ahmad Zakki; Yusuke Hiraku; Cheng-Ai Wu; Hidekuni Inadera (Apoptosis, 2021)

Not vegetation itself but mis-revegetation reduces water resources - Guoyi Zhou; Jun Xia; Ping Zhou; Tingting Shi; Lin Li (Science China Earth Sciences, 2021)

TRIC-A regulates intracellular Ca2+ homeostasis in cardiomyocytes - Xinyu Zhou; Ang Li; Pei-hui Lin; Jingsong Zhou; Jianjie Ma (Pflügers Archiv - European Journal of Physiology, 2021)
Trimeric intracellular cation (TRIC) channels have been identified as monovalent cation channels that are located in the ER/SR membrane. Two isoforms discovered in mammals are TRIC-A (TMEM38a) and TRIC-B (TMEM38b). TRIC-B ubiquitously expresses in all tissues, and TRIC-B −/− mice is lethal at the neonatal stage. TRIC-A mainly expresses in excitable cells. TRIC-A −/− mice survive normally but show abnormal SR Ca 2+ handling in both skeletal and cardiac muscle cells. Importantly, TRIC-A mutations have been identified in human patients with stress-induced arrhythmia. In the past decade, important discoveries have been made to understand the structure and function of TRIC channels, especially its role in regulating intracellular Ca 2+ homeostasis. In this review article, we focus on the potential roles of TRIC-A in regulating cardiac function, particularly its effects on intracellular Ca 2+ signaling of cardiomyocytes and discuss the current knowledge gaps.

Simulation of the fragmentation and propagation of jointed rock masses in rockslides: DEM modeling and physical experimental verification - Qi-wen Lin; Qian-Gong Cheng; Yu Xie; Feng-shou Zhang; Kun Li; Yu-feng Wang; Yuan-yuan Zhou (Landslides, 2021)

First report of natural infection of tomato by pepper mild mottle virus in China - Wen Peng Zhou; Yue Yue Li; Fan Li; Guan Lin Tan (Journal of Plant Pathology, 2021)

NLRP3 inflammasome priming and activation in cholestatic liver injury via the sphingosine 1-phosphate/S1P receptor 2/Gα(12/13)/MAPK signaling pathway - Lei Hou; Zhi Zhang; Le Yang; Na Chang; Xinhao Zhao; Xuan Zhou; Lin Yang; Liying Li (Journal of Molecular Medicine, 2021)

Assisted selection of eating quality progeny of indica (O. sativa L. ssp. indica) and japonica (O. sativa L. ssp. japonica) hybrids using rice starch properties - Ting Mao; Zhan Zhang; Shan Jun Ni; Yi Zhou Zhao; Xin Li; Li Li Zhang; Yan Liu; Cheng Shun Zhong; He Huang; Shao Lin Wang; Xu Li (Genetic Resources and Crop Evolution, 2021)

The contrasting effects of thermodynamic and dynamic processes on East Asian summer monsoon precipitation during the Last Glacial Maximum: a data-model comparison - Yong Sun; Haibin Wu; Masa Kageyama; Gilles Ramstein; Laurent Z. X. Li; Ning Tan; Yating Lin; Bo Liu; Weipeng Zheng; Wenchao Zhang; Liwei Zou; Tianjun Zhou (Climate Dynamics, 2021)
The Last Glacial Maximum (LGM; 21 ka BP) was the most recent glacial period when the global ice sheet volume was at a maximum. Therefore, the LGM can be used to investigate atmospheric dynamics under a climate that differed significantly from the present. This study quantitatively compares pollen records of boreal summer (June–July–August) precipitation with the PMIP3 LGM simulations. The data-model comparison shows an overall agreement on a drier than pre-industrial East Asian summer monsoon (EASM) climate. Nevertheless, 17 out of 55 records show a regional precipitation increase that is also simulated over the additional land mass area due to sea level drop. The thermodynamic and dynamic responses are analyzed to explain a drier LGM EASM as a combination of these two antagonistic mechanisms. Relatively low atmospheric moisture content was the main thermodynamic control on the lower LGM (relative to pre-industrial levels) EASM precipitation amounts in both the reconstructions and the models. In contrast, two dynamic processes in relation to stationary eddy activity act to increase EASM precipitation regionally in records and simulations, respectively. Precipitation increase in records is explained by dynamic enhancement of the horizontal moisture transport, while dynamic enhancement of the vertical moisture transport leads to simulated precipitation increase over the specific region where landmass was exposed during LGM along continental coastlines of China due to significant drop in sea level (relative to pre-industrial levels). Overall, the opposing effects of thermodynamic and dynamic processes on precipitation during the LGM provide a means to reconcile the spatial heterogeneity of recorded precipitation changes in sign, although data-model comparison suggests that the simulated dynamic wetting mechanism is too weak relative to the thermodynamic drying mechanism over data-model disagreement regions.

Development of a 100 MPa water–gas two-phase fluid pressurization device - Shengbin Li; Heping Li; Lin Chen; Hongbin Zhou (Acta Geochimica, 2021)

Sesquiterpenoids and meroterpenoids from a mangrove derived fungus Diaporthe sp. SCSIO 41011 - Xiao-Wei Luo; Chun-Mei Chen; Kun-Long Li; Xiu-Ping Lin; Cheng-Hai Gao; Xue-Feng Zhou; Yong-Hong Liu (Natural Product Research, 2021)

Astrocyte-Derived Lactate Modulates the Passive Coping Response to Behavioral Challenge in Male Mice - Ya-Nan Yin; Jian Hu; Yi-Li Wei; Ze-Lin Li; Zhou-Cai Luo; Rui-Qi Wang; Ke-Xin Yang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Hydrothermal dolomitization in the Middle Permian in the Central Sichuan Basin, SW China: evidence from petrology, geochemistry, and fluid inclusions - Lin Qi; Yifan Gu; Puwei He; Zhanlei Wang; Yuqiang Jiang; Shun Li; Yadong Zhou (Arabian Journal of Geosciences, 2021)

Stocks and losses of soil organic carbon from Chinese vegetated coastal habitats - Chuancheng Fu; Yuan Li; Lin Zeng; Haibo Zhang; Chen Tu; Qian Zhou; Kuanxu Xiong; Jiaping Wu; Carlos M. Duarte; Peter Christie; Yongming Luo (Global Change Biology, 2021)
Global vegetated coastal habitats (VCHs) represent a large sink for organic carbon (OC) stored within their soils. The regional patterns and causes of spatial variation, however, remain uncertain. The sparsity and regional bias of studies on soil OC stocks from Chinese VCHs have limited the reliable estimation of their capacity as regional and global OC sinks. Here, we use field and published data from 262 sampled soil cores and 181 surface soils to report estimates of soil OC stocks, burial rates and losses of VCHs in China. We find that Chinese mangrove, salt marsh and seagrass habitats have relatively low OC stocks, storing 6.3 ± 0.6, 7.5 ± 0.6, and 1.6 ± 0.6 Tg C (±95% confidence interval) in the top meter of the soil profile with burial rates of 44 ± 17, 159 ± 57, and 6 ± 45 Gg C/year, respectively. The variability in the soil OC stocks is linked to biogeographic factors but is mostly impacted by sedimentary processes and anthropic activities. All habitats have experienced significant losses, resulting in estimated emissions of 94.2–395.4 Tg CO 2 e (carbon dioxide equivalent) over the past 70 years. Reversing this trend through conservation and restoration measures has, therefore, great potential in contributing to the mitigation of climate change while providing additional benefits. This assessment, on a national scale from highly sedimentary environments under intensive anthropogenic pressures, provides important insights into blue carbon sink mechanism and sequestration capacities, thus contributing to the synchronous progression of global blue carbon management.

Heterosis-associated genes confer high yield in super hybrid rice - Tianzi Lin; Cong Zhou; Gaoming Chen; Jun Yu; Wei Wu; Yuwei Ge; Xiaolan Liu; Jin Li; Xingzhou Jiang; Weijie Tang; Yunlu Tian; Zhigang Zhao; et al. (Theoretical and Applied Genetics, 2020)
Key message Heterosis QTLs, including qSS7 and qHD8, with dominance effects were identified through GBS and large-scale phenotyping of CSSLs and hybrid F 1 populations in a paddy field. Abstract Heterosis has contributed immensely to agricultural production, but its genetic basis is unclear. We evaluated dominance effects by creating two hybrid populations: a B-homo set with a homozygous background and heterozygous chromosomal segments and a B-heter set with a heterozygous background and homozygous segments. This was achieved by crossing a set of 156 backcrossed-derived chromosome segment substitution lines (CSSLs) with their recurrent parent (9311), the male parent of the first super-high-yield hybrid Liangyoupei9 (LYP9), and with the female parent (PA64s) of the hybrid. The CSSLs were subjected to a genotyping-by-sequencing analysis to develop a genetic map of segments introduced from the PA64s. We evaluated the heterotic effects on eight yield-related traits in the hybrid variety and F 1 populations in large-scale field experiments over 2 years. Using a linkage map consisting of high-density SNPs, we identified heterosis-associated genes in LYP9. Five candidate genes contributed to the high yield of LYP9, with qSS7 and qHD8 repeatedly detected in both B-hybrid populations. The heterozygous segments harboring qSS7 and qHD8 showed dominance effects that contributed to the heterosis of yield components in the hybrid rice variety Liangyoupei9.

Adakitic rocks at convergent plate boundaries: Compositions and petrogenesis - Qiang Wang; Lulu Hao; Xiuzheng Zhang; Jinsheng Zhou; Jun Wang; Qiwei Li; Lin Ma; Long Zhang; Yue Qi; Gongjian Tang; Wei Dan; Jingjing Fan (Science China Earth Sciences, 2020)

The origin of arc basalts: New advances and remaining questions - Yigang Xu; Qiang Wang; Gongjian Tang; Jun Wang; Hongyan Li; Jinsheng Zhou; Qiwei Li; Yue Qi; Pingping Liu; Lin Ma; Jingjing Fan (Science China Earth Sciences, 2020)

AMPK Ameliorates Tau Acetylation and Memory Impairment Through Sirt1 - Lin Wang; Fang-Xiao Shi; Na Li; Yun Cao; Ying Lei; Jian-Zhi Wang; Qing Tian; Xin-Wen Zhou (Molecular Neurobiology, 2020)

Effects of MC-LR on histological structure and cell apoptosis in the kidney of grass carp (Ctenopharyngodon idella) - Li He; Lin Liu; Changgao Lin; Jiming Ruan; Ximei Liang; Ying Zhou; Lili Wei (Fish Physiology and Biochemistry, 2020)

Epidemiological analysis of Group A Streptococcus infections in a hospital in Beijing, China - Hongxin Li; Lin Zhou; Yong Zhao; Lijuan Ma; Jing Xu; Yan Liu; Qin Qin; Jin Hu; Xiaoyan Liu (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Differences in functional connectivity density among subtypes of schizophrenic auditory hallucination - Chuanjun Zhuo; Gongying Li; Feng Ji; Ce Chen; Deguo Jiang; Xiaodong Lin; Yong Xu; Hongjun Tian; Lina Wang; Chunhua Zhou; Xiao Lin (Brain Imaging and Behavior, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Exploring the potential of deep factorization machine and various gradient boosting models in modeling daily reference evapotranspiration in China - Zhigao Zhou; Lin Zhao; Aiwen Lin; Wenmin Qin; Yunbo Lu; Jingyi Li; Yang Zhong; Lijie He (Arabian Journal of Geosciences, 2020)

Illumina sequencing revealed roles of microRNAs in different aluminum tolerance of two citrus species - Yang-Fei Zhou; Yan-Yu Wang; Wei-Wei Chen; Li-Song Chen; Lin-Tong Yang (Physiology and Molecular Biology of Plants, 2020)

Genetic diversity analysis reveals new badnaviruses infecting banana in South China - Xue-Qin Rao; Zi-Lin Wu; Wan Wang; Lin Zhou; Jie Sun; Hua-Ping Li (Journal of Plant Pathology, 2020)

Effects of high-intensity interval training on gut microbiota profiles in 12 months’ old ICR mice - Guiping Wang; Huanhuan Zhou; Lin Zhang; Ruyi Li; Li Luo; Zengli Yu; Zhongxiao Wan (Journal of Physiology and Biochemistry, 2020)

Adaptive transgenerational effects remain significant - Yuan‐Ye Zhang; Junjie Yin; Ming Zhou; Zeru Lin; Qingshun Q. Li (Ecology Letters, 2020)
The comment by Sánchez‐Tójar et al . (2020, Ecol Lett) questioned the methodology, transparency and conclusion of our study (Ecol Lett, 22, 2019, 1976). The comment has overlooked important evolutionary assumptions in their reanalysis, and the issues raised were in fact dealt with through the peer‐review process. Far from being biased, the key conclusion of our meta‐analysis still stands; transgenerational effects are largely adaptive.

Surface display system for probiotics and its application in aquaculture - Yuan‐Yuan Yao; Ya‐Lin Yang; Chen‐Chen Gao; Feng‐Li Zhang; Rui Xia; Dong Li; Juan Hu; Chao Ran; Zhen Zhang; Jihong Liu‐Clarke; Zhi‐Gang Zhou (Reviews in Aquaculture, 2020)
Aquaculture is a fast‐growing and rapidly expanding industry in the world. Probiotics are widely used in aquaculture and have provided benefits to aquatic animal health, and it is also a promising alternative to antibiotics for control of fish diseases. With the development of biotechnology, new expression systems and novel techniques for the surface display of heterologous proteins in surface of probiotics cells have been developed. This review provides an overview of the systems and strategies for displaying functional proteins on the surface of probiotics commonly used in aquaculture, which are Bacillus subtilis , Bacillus thuringiensis , lactic acid bacteria represented by Lactococcus lactis and yeast. Their applications in aquaculture especially for oral vaccine development afforded by this technology and prospects and challenges associated with this technology are also highlighted.

COMT-Val158Met polymorphism modulates antipsychotic effects on auditory verbal hallucinations and temporal lobe gray matter volumes in healthy individuals—symptom relief accompanied by worrisome volume reductions - Chuanjun Zhuo; Langlang Cheng; Gongying Li; Yong Xu; Rixing Jing; Shen Li; Li Zhang; Xiaodong Lin; Chunhua Zhou (Brain Imaging and Behavior, 2020)
Investigation of auditory verbal hallucinations (AVHs) in schizophrenics is complicated by psychiatric symptoms. Investigating healthy individuals with AVHs (H-AVHs) can obviate such confounding factors. The objective of this study was to explore the effects of antipsychotic treatment on AVHs and gray matter volumes (GMVs) in H-AVH subjects and whether such are effects are influenced by COMT - Val158Met genotype. Magnetic resonance imaging (MRI) and genotyping studies were completed for 42 H-AVH subjects and 42 well-matched healthy controls (HCs). COMT-Met/Met homozygotes (158th codon) were identified as COMT-Met genotype; COMT-Met/Val heterozygotes and COMT-Val/Val homozygotes were identified as COMT-Val genotype. Data were compared across groups (H-AVH vs. HC, and between genotypes) with two-sample t-tests. The H-AVH COMT-Met group showed a stronger response to antipsychotic treatment than the H-AVH COMT-Val group ( p < 0.001). Both H-AVH genotype groups exhibited temporal lobe GMV reductions after treatment, and relative to their respective genotype-matched HC groups. Antipsychotic treatment effects in H-AVH subjects were influenced by COMT-Val158Met genotype and associated with widespread GMV reductions. These findings provide clues for further exploration of treatment targets for AVHs. Treatment associated GMV reductions, however, raise concerns about use of antipsychotics in H-AVH subjects.

A study on the application of the distributed optical fiber sensing monitoring technology in the process of dismantling temporary tunnel shoring - Zi-Xiang Li; Gong-Yu Hou; Tao Hu; Tian-Ci Zhou; Hai-Lin Xiao (Arabian Journal of Geosciences, 2020)

Correction to: Telomerase reconstitution contributes to resetting of circadian rhythm in fibroblasts - Yi Qu; Meng Mao; Xihong Li; Yanyou Liu; Jianmin Ding; Zhou Jiang; Chaomin Wan; Lin Zhang; Zhengrong Wang; Dezhi Mu (Molecular and Cellular Biochemistry, 2020)

Gastrointestinal involvement of COVID-19 and potential faecal transmission of SARS-CoV-2 - Min Song; Zong-lin Li; Ye-jiang Zhou; Gang Tian; Ting Ye; Zhang-rui Zeng; Jian Deng; Hong Wan; Qing Li; Jin-bo Liu (Journal of Zhejiang University-SCIENCE B, 2020)

Evolution of Neolithic site distribution (9.0–4.0 ka BP) in Anhui, East China - Li Wu; Xiaoling Sun; Wei Sun; Cheng Zhu; Tongxin Zhu; Shuguang Lu; Hui Zhou; Qingchun Guo; Houchun Guan; Wei Xie; Rui Ke; Guiping Lin (Journal of Geographical Sciences, 2020)

Effect of Calcium-Based Catalysts on Pyrolysis Liquid Products from Municipal Sludge - Wei Luo; Yi-Feng Su; Qing Hu; Huai-Lin Yin; Shuo Wang; Li-Jiao Ao; Xiao-Xi Wen; Sheng-Xiong Huang; Nan Zhou; Wei Zhang; Zhi Zhou (BioEnergy Research, 2020)