First report of chilli veinal mottle virus infecting tobacco in Guizhou, China - Yue Chen; Ting Ting Li; Jing Zhong; Li Ling Zhao; Ya Li Guo; Ye Chun Lin; Gui Gao; Yi Cao; Ming Ding (Journal of Plant Pathology, 2022)

A SOM−RBFnn-Based Calibration Algorithm of Modeled Significant Wave Height for Nearshore Areas - Hengyu Hu; Zhengwei He; Yanfang Ling; Junmin Li; Lu Sun; Bo Li; Junliang Liu; Wuyang Chen (Journal of Marine Science and Engineering, 2022)
In this paper, a calibration algorithm for forecasting the significant wave height (SWH) in nearshore areas is proposed, based on artificial neural networks. The algorithm has two features: first, it is based on SOM−BRFnn (self−organizing map–radial basis function neural network) to better reflect the clustering characteristics of the input parameters regarding wind and wave. In addition, the high-frequency variation part and the low-frequency variation part of SWH are separated by a threshold of 24 h to better describe the diurnal variation of SWH under the influence of tidal current. The algorithm is applied to the nearshore region of Nan-ao Island in the northeastern South China Sea. The results show that the algorithm can effectively correct the modeling results of nearshore SWH. Compared with the original outputs of the ERA5 model, the correlation coefficient is increased from 0.472 to 0.774, the root mean square error is reduced from 0.252 m to 0.103 m, and the mean relative error is reduced from 41% to 17.6%, respectively. Further analysis indicates that the frequency division is crucial in realizing the correction of the high-frequency variation of SWH. The results have reference significance for the application of wave numerical models in coastal areas.

Hypoxia Stress Induces Tissue Damage, Immune Defense, and Oxygen Transport Change in Gill of Silver Carp (Hypophthalmichthys molitrix): Evaluation on Hypoxia by Using Transcriptomics - Xiaohui Li; Chen Ling; Qiaoxin Wang; Cui Feng; Xiangzhong Luo; Hang Sha; Guoyu He; Guiwei Zou; Hongwei Liang (Frontiers in Marine Science, 2022)
The silver carp ( Hypophthalmichthys molitrix ) is an economically, as well as environmentally, important fish that harbors low environmental hypoxia tolerance and frequently contributes to a loss of aquaculture productivity. The gill is the first tissue attacked by hypoxia; however, the response of the gills of H. molitrix to hypoxia stress at the tissue, cellular, and molecular levels has not been clearly established. The influence of hypoxia on histological features along with gene expression in silver carp gills were explored in this research. The hematoxylin and eosin-stained sections and electron microscopy examinations of gills indicated that the gill lamellae were seriously twisted, gill filaments were dehisced, and the swelling and shedding of epithelial cell layer in the gill tissue were intensified along with the degree of hypoxia. In the hypoxia, semi-asphyxia, and asphyxia groups, the gill transcriptomic assessment of shifts in key genes, as well as modulatory networks in response to hypoxic conditions revealed 587, 725, and 748 differentially expressed genes, respectively. These genes are abundant in immune response signaling cascades (e.g., complement and coagulation cascades, Nucleotide-binding and oligomerization domain (NOD)-like receptor signaling cascade, and differentiation of Th1 along with Th2 cells) and oxygen transport [e.g., MAPK, PI3K-Akt, and hypoxia-inducible factor 1 (HIF-1) signaling cascades]. Genes linked to immune response (e.g., c2 , c3 , c6 , klf4 , cxcr4 , cd45 , and cd40 ) and oxygen transport (e.g., egln1 , egln3 , epo , ldh , and vegfa ) were additionally identified. According to our findings, the silver carp may be using “HIF-1” to obtain additional oxygen during hypoxia. These findings illustrate that hypoxia stress might damage gill tissue, trigger an immunological response, and activate HIF-1 signaling to increase oxygen availability under hypoxic situations. The findings of this work will help scientists better understand the molecular mechanisms driving hypoxia responses in hypoxia-sensitive fish and speed up the development of hypoxia-resistant varieties.

Porewater-Derived Blue Carbon Outwelling and Greenhouse Gas Emissions in a Subtropical Multi-Species Saltmarsh - Peiyuan Zhu; Xiaogang Chen; Yan Zhang; Qianyu Zhang; Xuan Wu; Huawen Zhao; Liang Qi; Xuexin Shao; Ling Li (Frontiers in Marine Science, 2022)
Saltmarshes can sequester atmospheric CO 2 in sediments, but limited studies have quantified porewater-derived carbon exports and identified related carbon sources. Here, we estimated porewater exchange, carbon outwelling, and greenhouse gas emissions in a subtropical multi-species saltmarsh. The radon-based porewater exchange rate was estimated to be 5.60 ± 2.78 cm d -1 . As the most dominant (~90%) carbon species, dissolved inorganic carbon (DIC) fluxes through porewater exchange and outwelling were 447 ± 227 and 1200 ± 61 mmol m -2 d -1 , respectively, which were 1.2 and 3.2 times that of carbon burial. As most DIC can remain in the ocean for a long time, porewater-derived DIC outwelling represents another important carbon sink, in addition to carbon burial. CO 2 and CH 4 emissions from creek water were 54.6 ± 0.5 and 0.19 ± 0.01 mmol m -2 d -1 , respectively, which could offset 16% of carbon burial. The δ 13 C and C/N ratios suggest that saltmarsh organic carbon mainly originates from the C3 plant Scirpus mariqueter rather than the C4 plant Spartina alterniflora . Overall, we suggest that porewater-derived DIC outwelling is an important long-term carbon sink in multi-species saltmarshes, providing a scientific basis for the protection and restoration of saltmarshes in the context of global climate change.

Treatment of Ammonium-Nitrogen–Contaminated Groundwater by Tidal Flow Constructed Wetlands Using Different Substrates: Evaluation of Performance and Microbial Nitrogen Removal Pathways - Dan Xu; Huilan Ling; Zebing Li; Yun Li; Renxiang Chen; Shuo Cai; Bai Gao (Water, Air, & Soil Pollution, 2022)

Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities - Ying-Ying Chen; Jiang-Ping Hou; Ling Huang; Afsar Khan; Fei-Fei Xing; Xiao-Han Zhang; De-Feng Han; Shi-Li Yan; Gui-Dong Cao; Qi-Yang Jiao; Dejie Liu; Xuwei Zhu; et al. (Natural Product Research, 2022)

Cavin-1 promotes M2 macrophages/microglia polarization via SOCS3 - Wei Huang; Yiyi Hong; Wenjing He; Li Jiang; Wen Deng; Biyan Peng; Fen Tang; Chaolan Shen; Qianqian Lan; Hui Huang; Haibin Zhong; Jian Lv; et al. (Inflammation Research, 2022)

Genetic diversity and population structure of Curcuma alismatifolia Gagnep. accessions revealed by SSR markers - Hui-Wen Yu; Ling-Jun Ke; Yi-Lan Xiao; Si-Jia Chen; Yuan-Yuan Li; Qi-Lin Tian; Yun-He Li; Jin-Shui Lin; Luan-Mei Lu (Genetic Resources and Crop Evolution, 2022)

Effects of synthetic nitrification inhibitor (3,4-dimethylpyrazole phosphate; DMPP) and biological nitrification inhibitor (methyl 3-(4-hydroxyphenyl) propionate; MHPP) on the gross N nitrification rate and ammonia oxidizers in two contrasting soils - Ting Lan; Mengxiao Li; Xiaoqian He; Ouping Deng; Wei Zhou; Ling Luo; Guangdeng Chen; Shu Yuan; Jing Ling; Min Zeng; Xuesong Gao (Biology and Fertility of Soils, 2022)

Meta‐analysis of diazotrophic signatures across terrestrial ecosystems at the continental scale - Chen Zhu; Ville‐Petri Friman; Ling Li; Qicheng Xu; Junjie Guo; Shiwei Guo; Qirong Shen; Ning Ling (Environmental Microbiology, 2022)
Summary Biological nitrogen fixation performed by diazotrophs forms a cornerstone of Earth's terrestrial ecosystem productivity. However, the composition, diversity and distribution of soil diazotrophs are poorly understood across different soil ecosystems. Furthermore, the biological potential of the key diazotroph species in relation to key environmental parameters is unknown. To address this, we used meta‐analysis approach to merge together 39 independent diazotroph amplicon sequencing ( nifH gene) datasets consisting of 1988 independent soil samples. We then employed multiple statistical analyses and machine‐learning approaches to compare diazotroph community differences and indicator species between terrestrial ecosystems on a global scale. The distribution, composition and structure of diazotroph communities varied across seven different terrestrial ecosystems, with community composition exhibiting an especially clear effect. The Cyanobacteria were the most abundant taxa in crust ecosystems (accounting for ~45% of diazotrophs), while other terrestrial ecosystems were dominated by Proteobacteria , including Alpha ‐, Beta ‐ and Gamma ‐ Proteobacteria (accounting for ~70% of diazotrophs). Farmland ecosystems harboured the highest and crust ecosystems the lowest alpha and phylogenetic diversities. Azospirillum zeae , Skermanella aerolata and four Bradyrhizobium species were identified as key indicator species of potential diazotroph activity. Overall, diazotroph abundances and distribution were affected by multiple environmental parameters, including soil pH, nitrogen, organic carbon, C:N ratio and annual mean precipitation and temperature. Together, our findings suggest that based on the relative abundance and diversity of nifH marker gene, diazotrophs have adapted to a range of environmental niches globally.

The mouse resource at National Resource Center for Mutant Mice - Cunxiang Ju; Juan Liang; Mingkun Zhang; Jinlong Zhao; Ling’en Li; Shuai Chen; Jing Zhao; Xiang Gao (Mammalian Genome, 2022)

Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China - Tie-Ning Zhang; Qi-Jun Wu; Yan-Hong Huang; Jing Li; Zong-Jiao Chen; Li-Li Li; Yan-Ling Chen; Shu Liu; Cheng-Zhi Jiang; Yu-Hong Zhao (Environmental Science and Pollution Research, 2022)

Using Caenorhabditis elegans to assess the ecological health risks of heavy metals in soil and sediments around Dabaoshan Mine, China - Xin Li; Qingqing Yang; Ling Wang; Chuxin Song; Lufeng Chen; Jie Zhang; Yong Liang (Environmental Science and Pollution Research, 2022)

Effectiveness of Disinfectants Suitable for Inactivating SARS-CoV-2 at Cold-Chain Temperature - Xiaosong Wu; Yin Chen; Ling Wang; Xiling Guo; Lunbiao Cui; Yiming Shen; Fang Li; Hong Sun; Liubo Zhang; Jin Shen; Yan Xu (Food and Environmental Virology, 2022)

Reference gene selection for quantitative RT-PCR in Miscanthus sacchariflorus under abiotic stress conditions - Junqin Zong; Jingbo Chen; Ling Li; Jianjian Li; Dandan Li; Jingjing Wang; Jun Liu; Jianxiu Liu (Molecular Biology Reports, 2022)

Estrogen alleviates hepatocyte necroptosis depending on GPER in hepatic ischemia reperfusion injury - Zhonglin Li; Liuying Chen; Huikuan Chu; Weijun Wang; Ling Yang (Journal of Physiology and Biochemistry, 2022)

Publisher Correction to: Compression Sleeve Changes Corticomuscular Connectivity and Sensorimotor Function - Wen‑Wen Yang; Li‑Ling Hope Pan; Chen‑Sheng Chen; Shun‑Hwa Wei; Chiang Liu; Li‑Wei Chou (Journal of Medical and Biological Engineering, 2022)

Gut microbiome diversity mediates the association between right dorsolateral prefrontal cortex and anxiety level - Xinyue Huang; Lei Li; Zihan Ling; Leying Gao; Huafu Chen; Xujun Duan (Brain Imaging and Behavior, 2022)

Pattern of cerebellar grey matter loss associated with ataxia severity in spinocerebellar ataxias type 3: a multi-voxel pattern analysis - Jianping Hu; Xinyuan Chen; Mengcheng Li; Hao-Ling Xu; Ziqiang Huang; Naping Chen; Yuqing Tu; Qunlin Chen; Shirui Gan; Dairong Cao (Brain Imaging and Behavior, 2022)

Multiple Modulating Processes for Intensive Tropical Cyclone Activity Affecting Taiwan in September 2016 - Wei-Teh Li; Jau-Ming Chen; Ruo-Shan Tseng; Tzu-Ling Lai (Asia-Pacific Journal of Atmospheric Sciences, 2022)

New paraconic acids from the endophytic fungus Xylariaceae sp. J4 - Chao Yuan; Xue-Chun Shu; Lin Fan; Ying-Bo Zhang; Ling-Liang Guan; Fu-Lai Yu; Xiao-Lu Chen; Gang Li (Natural Product Research, 2022)

A feasible vibration measurement and active control method of reinforced concrete lightweight pier railway bridges for heavy-haul monorail trains - Ling-kun Chen; Li-zhong Jiang; Rui Li; Qiao Li; Ming Zhang; Nan Zhang; Jin-zhang Luo; Liang Ling; Sheng-yang Zhu (European Journal of Environmental and Civil Engineering, 2022)

Fruit and vegetable consumption, cardiovascular disease, and all-cause mortality in China - Jun Wang; Fangchao Liu; Jianxin Li; Keyong Huang; Xueli Yang; Jichun Chen; Xiaoqing Liu; Jie Cao; Shufeng Chen; Chong Shen; Ling Yu; Fanghong Lu; et al. (Science China Life Sciences, 2022)

Spatio-temporal analysis of the coupling relationship between urbanization and eco-environment in backward regions of China - Hao Chen; Ling Liu; Jiaohui Fang; Changchao Li; Lifei Wang; Quan Quan; Jian Liu (Environmental Science and Pollution Research, 2022)

Identification of bacterial blight resistance genes in rice landraces from Yunnan Province, China - Caimei Zhao; Fuyou Yin; Ling Chen; Dingqin Li; Suqin Xiao; Qiaofang Zhong; Bo Wang; Xue Ke; Jian Fu; Xiang Li; Yue Chen; Lingxian Wang; et al. (Australasian Plant Pathology, 2022)
Bacterial blight (BB), a serious bacterial disease caused by pathogen Xanthomonas oryzae pv. oryzae ( Xoo ) affects rice growth and yield. Yunnan Province is regarded as a center of rice diversity in China and indeed the world, and has abundant rice landrace resources, which may offer prospective candidate donors in rice improvement and breeding. In this study, a set of 200 rice landraces were evaluated to determine their resistance to 10 pathogenic Xoo strains resistance by the leaf-clipping method. The results indicated that the tested rice landraces had different resistance levels against different Xoo strains. Multiple comparisons showed that the Xoo strain PXO99 was virulent to the tested rice landraces. Sixty-six rice landraces conferred resistance against at least one Xoo strain. These resistant rice landraces screened were then performed the presence of 14 cloned BB resistance genes by closely linked molecular markers and designed specific primers. The results showed that none of these resistant accessions contained xa13 , Xa21 , Xa27 , and Xa45(t) homologous fragments, while 9, 24, 4, 7, 9, 15, 1, 5, 4 and 27 accessions contained Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa7 , Xa10 , Xa23 and xa25 homologous fragments, respectively. Sequence analysis further revealed that nucleotide variations around functional nucleotide polymorphisms region were observed within these accessions containing the Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa10 , Xa23 and xa25 homologous fragments. These results along with phenotypic resistance spectrum supported that these accessions carried nine resistance homologous genes. Only one accession (Qishanggu_Wenshan) carried the Xa7 resistance gene. We also found that some resistant rice landraces, especially Xilandigu_Baoshan, and Laoyaling_Lincang without the above resistance genes, which mediated broad spectrum resistance to multiple Xoo strains, were identified as potential sources for breeding rice lines resistance to BB.

Mongoliitalea daihaiensis sp. nov., isolated from Daihai Lake in Inner Mongolia - Kai Jiang; Bo Yuan; Chun Ling Cao; Chen Ying Zhang; Ruo Xuan Li; Yan An (Archives of Microbiology, 2022)

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

Recent Advances in Enhancement of Dissolution and Supersaturation of Poorly Water-Soluble Drug in Amorphous Pharmaceutical Solids: A Review - Qin Shi; Fang Li; Stacy Yeh; Sakib M. Moinuddin; Junbo Xin; Jia Xu; Hao Chen; Bai Ling (AAPS PharmSciTech, 2021)

Standard litterbags underestimate early-stage lower-order root decomposition rate in a subtropical forest, China - Guan-tao Chen; Yu-qin Chen; Yong Peng; Hong-ling Hu; Jiu-long Xie; Gang Chen; Yin-long Xiao; Li Liu; Yi Tang; Li-hua Tu (Plant and Soil, 2021)

Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology - Yuhong Zhang; Xu Chen; Qiqi Wang; Congcong Du; Wenbin Lu; Hong Yuan; Zhenzhen Zhang; Danqing Li; Xing Ling; Xiang Ren; Yang Zhao; Qi Su; et al. (Journal of Molecular Medicine, 2021)

Clinical and Molecular Features of POLG-Related Sensory Ataxic Neuropathy with Dysarthria and Ophthalmoparesis - Li-Xi Li; Li-Ting Jiang; You-Gui Pan; Xiao-Long Zhang; Li-Zhen Pan; Zhi-Yu Nie; Yu-Hui Chen; Ling-Jing Jin (Journal of Molecular Neuroscience, 2021)

Controls of Wind-Driven Jet on the Distribution of Pelagic Cnidarians in the Midwestern South China Sea - Ruping Ge; Hongju Chen; Ling Li; Guangxing Liu; Bangqin Huang; Lisha Wang; Yunyun Zhuang; Xin Liu (Frontiers in Marine Science, 2021)
The coastal water transported by the combined action of southwest wind jet and anticyclonic eddy substantially influences the biological processes in the midwestern South China Sea. However, how the wind-driven jet affects the zooplankton community remains unclear. In this study, the species number, abundance, and vertical distribution of medusae were investigated in the wind-driven jet (WJR) and non-wind-driven jet regions (NWJR). The low-salinity and nutrient-rich coastal water substantially influenced species composition, abundance, and vertical distribution of medusae in the WJR. The species number of the meroplanktonic hydromedusae in the WJR was approximately twice that in the NWJR due to the horizontal transport of wind-driven jets. The abundances of holoplanktonic hydromedusae in WJR were 38.2 ± 9.3 ind⋅m –3 , which were thrice of that in the NWJR regions, caused by the abundant diet in the WJR. Additionally, only the abundance of medusae above the thermocline was affected by the coastal water in WJR, while these showed no significant difference below the thermocline between the WJR and the NWJR. Generalized additive model analyses suggested that the diet was the most important factor affecting the abundance of the holoplanktonic hydromedusae and siphonophore, whereas meroplanktonic hydromedusae were influenced by the combination of temperature, salinity, and diet.

Ice-binding proteins: a remarkable ice crystal regulator for frozen foods - Xu Chen; Xiaodan Shi; Xixi Cai; Fujia Yang; Ling Li; Jinhong Wu; Shaoyun Wang (Critical Reviews in Food Science and Nutrition, 2021)

Linking circular intronic RNA degradation and function in transcription by RNase H1 - Xiang Li; Jia-Lin Zhang; Yun-Ni Lei; Xiao-Qi Liu; Wei Xue; Yang Zhang; Fan Nan; Xiang Gao; Jun Zhang; Jia Wei; Li Yang; Ling-Ling Chen (Science China Life Sciences, 2021)

A Case Study on MJO Energy Transport Path in a Local Multi-scale Interaction Framework - Yuanwen Zhang; Guiwan Chen; Jian Ling; Shenming Fu; Chongyin Li (Advances in Atmospheric Sciences, 2021)

Petrogenesis and tectonic implication of lavas from the Yap Trench, western Pacific - Ling Chen; Limei Tang; Jichao Yang; Xiaohu Li; Wei Wang; Fengyou Chu; Jie Zhang (Acta Oceanologica Sinica, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Seasonal progression of photoprotection responses in different aged savin juniper plants under shade and sun - Jin-Ling Zhang; Xiao-Gang Li; Xue-Hua Xu; Hai-Peng Chen; Yu-Ling Li; Robert D. Guy (Trees, 2021)

Design and Evaluation of a Novel Transversal Double-bud Sugarcane Planter with Seed Pre-cutting - Jia-Qin Zhong; Li-Min Tao; Shang-Ping Li; Fang-Lan Ma; Yuan-Ling Chen (Sugar Tech, 2021)

Metabolic responses of Chinese perch (Siniperca chuatsi) to different levels of dietary carbohydrate - Yanpeng Zhang; Xu-fang Liang; Shan He; Jie Wang; Ling Li; Zhen Zhang; Jiao Li; Xu Chen; Lu Li; Muhammad Shoaib Alam (Fish Physiology and Biochemistry, 2021)

Four genetic loci affecting swine lung lesions identified by whole-genome sequencing-based association studies - Xinkai Tong; Tao Huang; Mingpeng Zhang; Jiaqi Chen; Zhou Zhang; Jingquan Li; Huipeng Du; Ziqi Ling; Zhongzi Wu; Bin Yang; Shijun Xiao; Huashui Ai (Science China Life Sciences, 2021)

Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype - Hao Li; Shihao Wu; Xia Ma; Xiao Li; Tianlin Cheng; Zhifang Chen; Jing Wu; Longbao Lv; Ling Li; Liqi Xu; Wenchao Wang; Yingzhou Hu; et al. (Neuroscience Bulletin, 2021)
Whether direct manipulation of Parkinson’s disease (PD) risk genes in the adult monkey brain can elicit a Parkinsonian phenotype remains an unsolved issue. Here, we used an adeno-associated virus serotype 9 (AAV9)-delivered CRISPR/Cas9 system to directly co-edit PINK1 and DJ-1 genes in the substantia nigras (SNs) of two monkey groups: an old group and a middle-aged group. After the operation, the old group exhibited all the classic PD symptoms, including bradykinesia, tremor, and postural instability, accompanied by key pathological hallmarks of PD, such as severe nigral dopaminergic neuron loss (>64%) and evident α-synuclein pathology in the gene-edited SN. In contrast, the phenotype of their middle-aged counterparts, which also showed clear PD symptoms and pathological hallmarks, were less severe. In addition to the higher final total PD scores and more severe pathological changes, the old group were also more susceptible to gene editing by showing a faster process of PD progression. These results suggested that both genetic and aging factors played important roles in the development of PD in the monkeys. Taken together, this system can effectively develop a large number of genetically-edited PD monkeys in a short time (6–10 months), and thus provides a practical transgenic monkey model for future PD studies.

A De Novo SEMA6B Variant in a Chinese Patient with Progressive Myoclonic Epilepsy-11 and Review of the Literature - Qian Li; Min Liu; Dan-ping Huang; Tao Li; Jing Huang; Ping Jiang; Wei-hao Ling; Xu-qin Chen (Journal of Molecular Neuroscience, 2021)

Effects of nFe3O4 capping on phosphorus release from sediments in a eutrophic lake - Xiang Chen; Ling Liu; Wenming Yan; Minjuan Li; Xiaolei Xing; Qi Li; Liangzhen Zhu; Tingfeng Wu; Xiangyu He (Environmental Science and Pollution Research, 2021)

Numerical modeling of 3D DC resistivity method in the mixed space-wavenumber domain - Shi-Kun Dai; Jia-Xuan Ling; Qing-Rui Chen; Kun Li; Qian-Jiang Zhang; Dong-Dong Zhao; Ying Zhang (Applied Geophysics, 2021)

An improved convolution perfectly matched layer for elastic second-order wave equation - Ling-Yun Yang; Guo-Chen Wu; Qing-Yang Li; Zhan-Yuan Liang (Applied Geophysics, 2021)

Modulation of the 5-HT 3 A receptor current by desacylbaldrinal - Li-Xia Wang; Hu-Lan Chen; Hong-Ling Yan; Fei Tang; Hai Zhang; Hong-Xiang Li; Qiang Ye; Cheng Peng; Yu-Zhu Tan (Natural Product Research, 2021)

Maternal exposure to sulfur dioxide and the risk of oral clefts in Liaoning Province, China: a population-based case-control study - Fang-Hua Liu; Ze Xing; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; et al. (Environmental Science and Pollution Research, 2021)

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

Vibrio nitrifigilis sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll - Wei-Sheng Huang; Li-Ting Wang; Jwo-Sheng Chen; Yen-Ting Chen; Sean Ting-Shyang Wei; Yin-Ru Chiang; Pei-Ling Wang; Tzong-Huei Lee; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Genome-Wide Identification and Expression Analysis of Heavy Metal Stress–Responsive Metallothionein Family Genes in Nicotiana tabacum - Qin Yu; Linshen He; Chunsong Huo; Xiaohan Jiang; Hua Chen; Run Wang; Minzhi Tang; Ling Dong; Ji Chen; Yonghao Li; Shunqin Zhu; Wanhong Liu (Plant Molecular Biology Reporter, 2021)

Rhizosphere microbiome modulated effects of biochar on ryegrass 15N uptake and rhizodeposited 13C allocation in soil - Yingyi Fu; Amit Kumar; Lijun Chen; Yuji Jiang; Ning Ling; Runze Wang; Qiong Pan; Bhupinder Pal Singh; Marc Redmile-Gordon; Lu Luan; Qin Li; Quan Shi; et al. (Plant and Soil, 2021)

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

Ameliorative effect of graphene nanosheets against arsenic-induced toxicity in mice by oral exposure - Huan Li; Bing Wu; Jingli Zhang; Yue Yu; Ling Chen; Su Liu (Environmental Science and Pollution Research, 2021)

Physical interactions facilitate sex change in the protogynous orange‐spotted grouper, Epinephelus coioides - Jiaxing Chen; Cheng Peng; Jingjun Huang; Herong Shi; Ling Xiao; Lin Tang; Haoran Lin; Shuisheng Li; Yong Zhang (Journal of Fish Biology, 2021)
Sex change in teleost fishes is commonly regulated by social factors. In species that exhibit protogynous sex change, such as the orange‐spotted grouper Epinephelus coioides , when the dominant males are removed from the social group, the most dominant female initiates sex change. The aim of this study was to determine the regulatory mechanisms of socially controlled sex change in E. coioides . We investigated the seasonal variation in social behaviours and sex change throughout the reproductive cycle of E. coioides , and defined the behaviour pattern of this fish during the establishment of a dominance hierarchy. The social behaviours and sex change in this fish were affected by season, and only occurred during the prebreeding season and breeding season. Therefore, a series of sensory isolation experiments was conducted during the breeding season to determine the role of physical, visual and olfactory cues in mediating socially controlled sex change. The results demonstrated that physical interactions between individuals in the social groups were crucial for the initiation and completion of sex change, whereas visual and olfactory cues alone were insufficient in stimulating sex change in dominant females. In addition, we propose that the steroid hormones 11‐ketotestosterone and cortisol are involved in regulating the initiation of socially controlled sex change.

Effects of Co-Applications of Biochar and Solid Digestate on Enzyme Activities and Heavy Metals Bioavailability in Cd-Polluted Greenhouse Soil - Shuaixing Xue; Fengfen Chen; Yuying Wang; Zhijiang Shao; Congguang Zhang; Ling Qiu; Yi Ran; Li He (Water, Air, & Soil Pollution, 2021)

Resveratrol-induced apoptosis is associated with regulating the miR-492/CD147 pathway in malignant melanoma cells - Shuang Zhao; Ling Tang; Wangqing Chen; Juan Su; Fangfang Li; Xiang Chen; Lisha Wu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

The Roles of Epinephelus coioides miR-122 in SGIV Infection and Replication - Hong-Yan Sun; Yu-Ling Su; Pin-Hong Li; Jia-Yang He; He-Jia Chen; Gang Wang; Shao-Wen Wang; Xiao-Hong Huang; You-Hua Huang; Qi-Wei Qin (Marine Biotechnology, 2021)
In mammals, mature miR-122 is 22 nucleotides long and can be involved in regulating a variety of physiological and biological pathways. In this study, the expression profile and effects of grouper Epinephelus coioides miR-122 response to Singapore grouper iridovirus (SGIV) infection were investigated. The sequences of mature microRNAs (miRNAs) from different organisms are highly conserved, and miR-122 from E. coioides exhibits high similarity to that from mammals and other fish. The expression of miR-122 was up-regulated during SGIV infection. Up-regulation of miR-122 could significantly enhance the cytopathic effects (CPE) induced by SGIV, the transcription levels of viral genes (MCP, VP19, LITAF and ICP18), and viral replication; reduce the expression of inflammatory factors (TNF-a, IL-6, and IL-8), and the activity of AP-1 and NF-κB, and miR-122 can bind the target gene p38α MAPK to regulate the SGIV-induced cell apoptosis and the protease activity of caspase-3. The results indicated that SGIV infection can up-regulate the expression of E. coioides miR-122, and up-regulation of miR-122 can affect the activation of inflammatory factors, the activity of AP-1 and NF-κB, and cell apoptosis to regulate viral replication and proliferation.

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Increased depression risk for elderly women with high blood levels of strontium and barium - Jia Lv; Yan-ling Li; Wen-qiang Ren; Rong Li; Jian-rong Chen; Chao Bao; Zhi-ping Du; Shun Feng; Ling Gu; Hui Gao; Kai-yong Liu; Lin-sheng Yang; et al. (Environmental Chemistry Letters, 2021)

Association Between Blood Heavy Metal Concentrations and Dyslipidemia in the Elderly - Xingmeng Zhu; Yong Fan; Jie Sheng; Ling Gu; Qi Tao; Rui Huang; Kaiyong Liu; Linsheng Yang; Guimei Chen; Hongjuan Cao; Kaichun Li; Fangbiao Tao; et al. (Biological Trace Element Research, 2021)

Activity evolution of landslides and debris flows after the Wenchuan earthquake in the Qipan catchment, Southwest China - Qing-yun Shi; Chuan Tang; Ling-feng Gong; Ming Chen; Ning Li; Wei Zhou; Jiang Xiong; Hai Tang; Xiao-di Wang; Ming-wei Li (Journal of Mountain Science, 2021)

Different Impacts of Madden-Julian Oscillation on Winter Rainfall over Southern China - Xiong Chen; Jian Ling; Chongyin Li; Lifeng Li; Minghao Yang (Journal of Meteorological Research, 2021)

Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71 - Ya-Ping Li; Mu-Qi Wang; Chen-Rui Liu; Hui-Ling Deng; Yuan Wu; Shuang-Suo Dang; Li-Hong Xu (Archives of Virology, 2021)

The mangrove CO 2 pump: Tidally driven pore‐water exchange - Xiaogang Chen; Isaac R. Santos; Mitchell Call; Gloria M. S. Reithmaier; Damien Maher; Ceylena Holloway; Praktan D. Wadnerkar; Paula Gómez‐Álvarez; Christian J. Sanders; Ling Li (Limnology and Oceanography, 2021)
Atmospheric carbon dioxide (CO 2 ) is fixed by mangrove vegetation and stored in its biomass and sediments. Part of the sediment carbon can be exported to coastal waters via tidally driven pore‐water exchange. Here, we quantify pore water‐derived dissolved CO 2 export using in situ, high‐resolution observations of 222 Rn and CO 2 over a spring‐neap tidal cycle in a mangrove‐fringed estuary (Coffs Creek, Australia). 222 Rn‐derived pore‐water exchange rates were 11.5–34.9 cm d −1 (23.0 ± 6.7) over 30 tidal cycles. Pore‐water exchange released CO 2 from intertidal sediment at rates of 61–213 (136 ± 43) mmol m −2 d −1 . This is equivalent to ~ 94% of the total CO 2 input into the estuary and approximately two times of the water‐atmosphere CO 2 emission. These observations reveal that tidal pumping is a major regulator of both mangrove pore‐water exchange and associated dissolved CO 2 export to the ocean. Combining our estimates with literature data, a first‐order global pore water‐derived dissolved CO 2 export from mangroves was estimated to be 83 ± 50 Tg C yr −1 . This is higher than an earlier estimates of global mangrove CO 2 emissions to the atmosphere (34.1 ± 5.4 Tg C yr −1 ) and carbon burial in sediments (18.4–34.4 Tg C yr −1 ), implying that pore water‐derived CO 2 escapes to the atmosphere within and beyond mangrove waters. Overall, CO 2 ‐rich pore water seems to be a widespread, important pathway of CO 2 into mangrove‐dominated estuaries and should be considered in mangrove carbon assessments in the context of global climate change and blue carbon.

A Fluorescent Visual Proton Donor and Photoacid Sterilant Based on Sulfonate‐conjugated BODIPY - Abbas Mohammed Ali; Jian Shao; Jia-Xin Wang; Qiu-Yun Chen; Yang Li; Ling-Ling Qu (Journal of Fluorescence, 2021)

Maternal exposure to ambient SO2 and risk of polydactyly and syndactyly: a population-based case-control study in Liaoning Province, China - Yu-Ting Jiang; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; Qi-Jun Wu (Environmental Science and Pollution Research, 2021)

Remediation of contaminated soil and groundwater using chemical reduction and solidification/stabilization method: a case study - Shi-Feng Lu; Yu-Lin Wu; Zhan Chen; Tao Li; Chao Shen; Lin-Kang Xuan; Ling Xu (Environmental Science and Pollution Research, 2021)

Accumulation and Depuration of Cd and its Effect on the Expressions of Metallothionein and Apoptotic Genes in Litopenaeus vannamei - Ling Li; Yu-Chun Shen; Jin-Rong Liang; Hu Liu; Tian-Ci Chen; Hui Guo (Bulletin of Environmental Contamination and Toxicology, 2021)

Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway - Jin Hou; Ling Zhao; Huaqiao Tang; Xiaoli He; Gang Ye; Fei Shi; Min Kang; Helin Chen; Yinglun Li (Biological Trace Element Research, 2021)

Arbuscular mycorrhizal colonization rate of an exotic plant, Galinsoga quadriradiata, in mountain ranges changes with altitude - Gang Liu; Rui-Ling Liu; Wen-Gang Zhang; Ying-Bo Yang; Xiao-Qiong Bi; Ming-Zhu Li; Xiao-Yan Chen; Hua Nie; Zhi-Hong Zhu (Mycorrhiza, 2021)

A global analysis on the systemic effects of antibiotics in cultured fish and their potential human health risk: a review - Samwel Mchele Limbu; Li‐Qiao Chen; Mei‐Ling Zhang; Zhen‐Yu Du (Reviews in Aquaculture, 2021)
The rearing of fish in intensive systems reduces their immunity leading to eruption of diseases, consequently prompting the use of antibiotics. Antibiotics are currently used in cultured fish globally to treat/prevent diseases. On the one hand, antibiotics used in aquaculture help to improve fish health by killing or inhibiting pathogenic bacteria proliferation. However, on the other hand, they cause multiple side effects. To date, information on systemic effects of antibiotics in cultured fish is scattered and their potential human health risk remains elusive. This review critically analyses and discusses the available information in the literature on the positive and negative effects of antibiotics in cultured fish and their potential human health risk via fish consumption. The review found 44 different antibiotics dominated by oxytetracycline were studied in various fish species worldwide. Antibiotics used in global aquaculture either decrease or increase fish growth and survival rates. They induce oxidative stress, which affect antioxidant and detoxification responses and cause host–microbiota dysbiosis. These changes compromise the fish immunity system, which ultimately lead to cellular damage. The toxicities generated inhibit the fish aerobic glycolysis, suppress lipogenesis and fatty acid β‐oxidation while increase energy demand by initiating gluconeogenesis and anaerobic glycolysis. Consumption of fish treated with antibiotics causes human health risk. Future studies are required on agents to restore dysfunctions induced by antibiotics in cultured fish, while attempts to limit their utilisation in aquaculture production are underway. [Correction added on 21 November 2020, after first online publication: The abstract has been amended to clarify the scope of the review.]

Siccirubricoccus phaeus sp. nov., isolated from oil reservoir water and emended description of the genus Siccirubricoccus - Fang-Ling Li; Ya-Xi Zhang; Ya-Kun Zhang; Wen-Feng Chen; Wen-Jun Li; Lei Wang (Antonie van Leeuwenhoek, 2021)

LINC00173 promotes the apoptosis of hypertrophic scar fibroblasts through increasing β-catenin expression - Qian Li; Xin Chen; Ling Chen; Hui Yan; Jun Li (Molecular and Cellular Biochemistry, 2021)

MSC-AS1 knockdown inhibits cell growth and temozolomide resistance by regulating miR-373-3p/CPEB4 axis in glioma through PI3K/Akt pathway - Chong Li; Shiyu Feng; Ling Chen (Molecular and Cellular Biochemistry, 2021)
Long non-coding RNAs (lncRNAs) have been widely reported to regulate the development and chemoresistance of a variety of tumors. Temozolomide (TMZ) is a first-line chemotherapy for treatment of glioma. However, the effect and the regulatory mechanism of lncRNA MSC-AS1 (MSC-AS1) in TMZ-resistant glioma remain unrevealed. Levels of MSC-AS1, microRNA-373-3p (miR-373-3p), and cytoplasmic polyadenylation element binding protein 4 (CPEB4) were determined by quantitative real-time polymerase chain reaction (qRT-PCR). All protein expression was detected by western blot. Cell viability and the half maximal inhibitory concentration (IC 50 ) value of TMZ was assessed by cell counting kit-8 (CCK-8) assay. Cell cloning ability and apoptosis were examined by colony formation and flow cytometry assays, respectively. Dual-luciferase reporter and RNA immunoprecipitation (RIP) assays were performed to verify the correlation between miR-373-3p and MSC-AS1 or CPEB4. The xenograft models were established to determine the effect of MSC-AS1 in vivo. MSC-AS1 was up-regulated in TMZ-resistant glioma tissues and cells, and glioma patients with high MSC-AS1 expression tend to have lower overall survival rate. MSC-AS1 suppression reduced the IC 50 value of TMZ and proliferation, promoted apoptosis and TMZ sensitivity, and affected PI3K/Akt pathway in TMZ-resistant glioma cells. MSC-AS1 acted as miR-373-3p sponge, and miR-373-3p directly targeted CPEB4. Silencing miR-373-3p reversed the promoting effect of MSC-AS1 or CPEB4 knockdown on TMZ sensitivity. Furthermore, MSC-AS1 knockdown inhibited TMZ-resistant glioma growth in vivo by regulating miR-373-3p/CPEB4 axis through PI3K/Akt pathway. Collectively, MSC-AS1 knockdown suppressed cell growth and the chemoresistance of glioma cells to TMZ by regulating miR-373-3p/CPEB4 axis in vitro and in vivo through activating PI3K/Akt pathway.

Compression Sleeve Changes Corticomuscular Connectivity and Sensorimotor Function - Wen-Wen Yang; Li-Ling Hope Pan; Chen-Sheng Chen; Shun-Hwa Wei; Chiang Liu; Li-Wei Chou (Journal of Medical and Biological Engineering, 2021)

The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish - Si-Lan Han; Yan Liu; Samwel M. Limbu; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2021)

Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients - Hou-wei Du; Jun-nian Chen; Xiao-bin Pan; Xiao-ling Chen; Yixian-Zhang; Shuang-fang Fang; Xiao-qing Li; Pin-cang Xia; Lei Gao; Hai-long Lin; Li-min Chen; Nan Liu (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

A coupled UV photolysis-biodegradation process for the treatment of decabrominated diphenyl ethers in an aerobic novel bioslurry reactor - Yi-Tang Chang; Huei-Chen Chen; Hsi-Ling Chou; Hui Li; Stephen A. Boyd (Environmental Science and Pollution Research, 2021)

The Association Between Trace Elements Exposure and the Cognition in the Elderly in China - Ling Gu; Jinhui Yu; Yong Fan; Sufang Wang; Linsheng Yang; Kaiyong Liu; Qunan Wang; Guimei Chen; Dongmei Zhang; Ying Ma; Li Wang; Annuo Liu; et al. (Biological Trace Element Research, 2021)

Quantitatively determine the dominant driving factors of the spatial—temporal changes of vegetation NPP in the Hengduan Mountain area during 2000–2015 - Shu-ting Chen; Bing Guo; Rui Zhang; Wen-qian Zang; Cui-xia Wei; Hong-wei Wu; Xiao Yang; Xiao-yan Zhen; Xing Li; Da-fu Zhang; Bao-min Han; Hai-ling Zhang (Journal of Mountain Science, 2021)

Maximum July–September temperatures derived from tree‐ring densities on the western Loess Plateau, China - Huiming Song; Ruochen Mei; Yu Liu; Daniel Nievergelt; Anne Verstege; Paolo Cherubini; Ruoshi Liu; Changfeng Sun; Qiang Li; Ling Chen; Xueli Zeng; Junqin Guo (International Journal of Climatology, 2021)
Tree‐ring densitometric studies conducted in semi‐arid regions are exceedingly rare. In this study, we evaluate a new maximum latewood density chronology from a collection of Picea purpurea trees growing in semi‐arid northwestern China for climatic reconstruction purposes. We find statistically significant correlations between annual maximum density variations and July–September maximum temperatures over the 1957–2014 calibration period. Using a linear model to transfer the density variations to temperature estimates, we then reconstruct maximum summer temperatures from 1840 to 2014. Statistical analyses and verification tests demonstrate that the resulting transfer function is both reliable and stable. The reconstructed temperature series shows strong inter‐annual and decadal variability. Several extremely cool and warm years are apparent on an inter‐annual scale, while three extended cool periods and a warm period are observed on a decadal scale. In addition, the reconstructed temperature series exhibits a pattern synchronous with that of the Indian monsoon index, as well as a moderate relationship to volcanic eruptions. This densitometric study reveals typical climatic variation characteristics and provides useful data for deepening our understanding of climate history in the semi‐arid regions of China.

Sialic Acid Conjugate–Modified Liposomal Dexamethasone Palmitate Targeting Neutrophils for Rheumatoid Arthritis Therapy: Influence of Particle Size - Shuo Wang; Shuaishuai Yang; Xiaoxue Lai; Yanzhi Song; Ling Hu; Cong Li; Tao Shi; Xinrong Liu; Yihui Deng; Guoliang Chen (AAPS PharmSciTech, 2021)

Application of 1H-NMR combined with qRT-PCR technology in the exploration of rosmarinic acid biosynthesis in hair roots of Salvia miltiorrhiza Bunge and Salvia castanea f. tomentosa Stib - Zhuoni Hou; Yuanyuan Li; Feng Su; Jipeng Chen; Xiaodan Zhang; Ling Xu; Dongfeng Yang; Zongsuo Liang (Planta, 2021)
Main conclusion Methyl jasmonate promotes the synthesis of rosmarinic acid in Salvia miltiorrhiza Bunge and Salvia castanea f. tomentos a Stib, and it promotes the latter more strongly. Abstract Salvia miltiorrhiza Bunge (SMB) is a traditional Chinese medicinal material, its water-soluble phenolic acid component rosmarinic acid has very important medicinal value. Salvia castanea f . tomentosa Stib (SCT) mainly distributed in Nyingchi, Tibet. Its pharmacological effects are similar to SMB, but its rosmarinic acid is significantly higher than the former. Methyl jasmonate (MJ) as an inducer can induce the synthesis of phenolic acids in SMB and SCT. However, the role of MJ on rosmarinic acid in SMB is controversial. Therefore, this study used SMB and SCT hair root as an experimental material and MJ as a variable. On one hand, exploring the controversial reports in SMB; on the other hand, comparing the differences in the mechanism of action of MJ on the phenolic acids in SMB and SCT. The content of related metabolites and the expression of key genes in the synthesis pathway of rosmarinic acid was analyzed by 1 H-NMR combined with qRT-PCR technology. Our research has reached the following conclusions: first of all, MJ promotes the accumulation of rosmarinic acid and related phenolic acids in the metabolic pathways of SMB and SCT. After MJ treatment, the content of related components and gene expression are increased. Second, compared to SMB, SCT has a stronger response to MJ. It is speculated that the different responses of secondary metabolism-related genes to MJ may lead to different metabolic responses of salvianolic acid between the two.

Observational study of super typhoon Meranti (2016) using satellite, surface drifter, Argo float and reanalysis data - Hui Chen; Shuang Li; Hailun He; Jinbao Song; Zheng Ling; Anzhou Cao; Zhongshui Zou; Wenli Qiao (Acta Oceanologica Sinica, 2021)

Design of the Blade under Low Flow Velocity for Horizontal Axis Tidal Current Turbine - Jun-Hua Chen; Xian-Cheng Wang; Hao Li; Chu-Hua Jiang; Ling-Jie Bao (Journal of Marine Science and Engineering, 2020)
The blade is the key component for energy capture in horizontal axis tidal current turbine, and the blade’s design is directly related to the efficiency of the power generation device. The seawater flow velocity is a crucial parameter for blade design. Since the seawater velocity changes constantly, it is extremely important to determine the design velocity of the blade. This article proposes a calculation method for the design velocity of the blade so that the designed blade can achieve better energy collection efficiency under a variable flow velocity. This study performed the following investigations: (1) The author tested and analyzed the seawater velocity variation at the experimental site, determining the designed flow velocity via calculations; (2) The author combined the blade element momentum and Wilson’s optimization design method using the MATLAB software to calculate the blade shape parameters and predict the performance under a number of different flow velocity forecasts; (3) When testing the device under sea conditions, the experimental results showed that the performance capture devices and digital projections are basically the same, which verifies the validity and effectiveness of the design method.

Dissipation Behavior and Residue Distribution of Famoxadone and Cymoxanil in Cucumber and Soil Ecosystem Under Open-Field Conditions - Jifa Rao; Ling Chen; Yujia Xiang; Jiayu Li; Xiao Chen; Yaoyu Zhou (Water, Air, & Soil Pollution, 2020)

Clinical characteristics and plasma antibody titer of patients with COVID-19 in Zhejiang, China - Wei-ling Xiang; Jing-jing Cheng; Lian-peng Wu; Bing-yu Chen; Wen-xin Li; Dan-ying Qiu; Wei Zhang; Fei-hang Ge; Dong Chen; Zhen Wang (Journal of Zhejiang University-SCIENCE B, 2020)

The extract of aquatic macrophyte Carex cinerascens induced colony formation in bloom-forming cyanobacterium Microcystis aeruginosa - Lin Li; Xiao-ling Jing; Ling Wang; Zhi-gao Zeng; Wen-hong Chen; Jia-hao Zhai; Si-qin Qi (Environmental Science and Pollution Research, 2020)

Examining the determinants of energy-related carbon emissions in Central Asia: country-level LMDI and EKC analysis during different phases - Fei Wang; Changjian Wang; Jing Chen; Zeng Li; Ling Li (Environment, Development and Sustainability, 2020)

Inconsistency between cortical reorganization and functional connectivity alteration in the sensorimotor cortex following incomplete cervical spinal cord injury - Xuejing Li; Qian Chen; Weimin Zheng; Xin Chen; Ling Wang; Wen Qin; Kuncheng Li; Jie Lu; Nan Chen (Brain Imaging and Behavior, 2020)

Compositional variations of active autotrophic bacteria in paddy soils with elevated CO2 and temperature - Chen Zhu; Ning Ling; Ling Li; Xiaoyu Liu; Michaela A. Dippold; Xuhui Zhang; Shiwei Guo; Yakov Kuzyakov; Qirong Shen (Soil Ecology Letters, 2020)

Effects of the Lower Airway Secretions on Airway Opening Pressures and Suction Pressures in Critically Ill COVID-19 Patients: A Computational Simulation - Zhenglong Chen; Ming Zhong; Li Jiang; Nanshan Chen; Shengjin Tu; Yuan Wei; Ling Sang; Xia Zheng; Chunyuan Zhang; Jiale Tao; Linhong Deng; Yuanlin Song (Annals of Biomedical Engineering, 2020)

Isotopic fingerprinting of dissolved iron sources in the deep western Pacific since the late Miocene - Ruolin Liu; Bai Guo; Maoyu Wang; Weiqiang Li; Tao Yang; Hongfei Ling; Tianyu Chen (Science China Earth Sciences, 2020)

Fasudil attenuates glial cell-mediated neuroinflammation via ERK1/2 and AKT signaling pathways after optic nerve crush - Wei Huang; Qianqian Lan; Li Jiang; Wenya Yan; Fen Tang; Chaolan Shen; Hui Huang; Haibin Zhong; Jian Lv; Siming Zeng; Min Li; Zhongxiang Mo; et al. (Molecular Biology Reports, 2020)

Sleep deprivation aggravated lipopolysaccharide/d-galactosamine-induced acute liver injury by suppressing melatonin production - Lu Liu; Li Zhang; Longjiang Li; Mengting Chen; Zhe Wang; Yi Shen; Jiayi Huang; Ling Tang (Inflammation Research, 2020)

Cloning and Characterization of a Ginsenoside-Hydrolyzing α-L-Arabinofuranosidase, CaAraf51, From Cellulosimicrobium aquatile Lyp51 - Sha-Sha Zuo; Yu-Chen Wang; Ling Zhu; Jiang-Yuan Zhao; Ming-Gang Li; Xiu-Lin Han; Meng-Liang Wen (Current Microbiology, 2020)

Combined addition of chemical and organic amendments enhances plant resistance to aboveground herbivores through increasing microbial abundance and diversity - Linhui Jiang; Michael Bonkowski; Ling Luo; Paul Kardol; Yu Zhang; Xiaoyun Chen; Daming Li; Zhenggao Xiao; Feng Hu; Manqiang Liu (Biology and Fertility of Soils, 2020)

CAS FGOALS-g3 Model Datasets for the CMIP6 Scenario Model Intercomparison Project (ScenarioMIP) - Ye Pu; Hongbo Liu; Ruojing Yan; Hao Yang; Kun Xia; Yiyuan Li; Li Dong; Lijuan Li; He Wang; Yan Nie; Mirong Song; Jinbo Xie; et al. (Advances in Atmospheric Sciences, 2020)
This paper describes the datasets from the Scenario Model Intercomparison Project (ScenarioMIP) simulation experiments run with the Chinese Academy of Sciences Flexible Global Ocean-Atmosphere-Land System Model, GridPoint version 3 (CAS FGOALS-g3). FGOALS-g3 is driven by eight shared socioeconomic pathways (SSPs) with different sets of future emission, concentration, and land-use scenarios. All Tier 1 and 2 experiments were carried out and were initialized using historical runs. A branch run method was used for the ensemble simulations. Model outputs were three-hourly, six-hourly, daily, and/or monthly mean values for the primary variables of the four component models. An evaluation and analysis of the simulations is also presented. The present results are expected to aid research into future climate change and socio-economic development.

Associations of egg consumption with incident cardiovascular disease and all-cause mortality - Xue Xia; Fangchao Liu; Xueli Yang; Jianxin Li; Jichun Chen; Xiaoqing Liu; Jie Cao; Chong Shen; Ling Yu; Yingxin Zhao; Xianping Wu; Liancheng Zhao; et al. (Science China Life Sciences, 2020)

Pattern Informatics and the Soup-of-Groups Model of Earthquakes: A Case Study of Italian Seismicity - Ling-Yun Chang; Chien-Chih Chen; Luciano Telesca; Hsien-Chi Li; S. A. Cheong (Pure and Applied Geophysics, 2020)

Transcriptome analysis of different rice cultivars provides novel insights into the rice response to bacterial leaf streak infection - Ling Lu; Dewei Yang; Dingzhong Tang; Shengping Li; Zhiwei Chen (Functional & Integrative Genomics, 2020)

Characterization of Pneumocystis jirovecii pneumonia at three tertiary comprehensive hospitals in southern China - Yan-Hui Chen; Xue-Yao Fang; Yue-Ting Li; Yan-Ling Liu; Ya-Ping Hang; Yan-Ping Xiao; Xing-Wei Cao; Qiao-Shi Zhong; Long-Hua Hu (Brazilian Journal of Microbiology, 2020)

First case of Shewanella indica isolated from a Bryde’s whale (Balaenoptera edeni) stranded in the northern Beibu Gulf, China - Jia Li; Richard W. McLaughlin; Mo Chen; Ying Li Liu; Hia Xia Xie; Xiao Ling Wan; Jun Ying Zhou; Jin Song Zheng (Antonie van Leeuwenhoek, 2020)

Impaired peroxisomal fat oxidation induces hepatic lipid accumulation and oxidative damage in Nile tilapia - Yan Liu; Si-Lan Han; Yuan Luo; Ling-Yu Li; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2020)

Transcriptome Analysis of Two Strains of Proteus mirabilis with Swarming Migration Deficiency Isolated from Patients with Urinary Tract Infection - Liang Peng; Ding-Qiang Chen; Guan-Ming Jiang; Jing-Yi Ou; Qiao Jiang; Li-Ting Zeng; Yi Xiao; Qiong-Yan Jiang; Ling Yang; Ning Sun (Current Microbiology, 2020)

Methane Seeps and Independent Methane Plumes in the South China Sea Offshore Taiwan - Susan Mau; Tzu-Hsuan Tu; Marius Becker; Christian dos Santos Ferreira; Jhen-Nien Chen; Li-Hung Lin; Pei-Ling Wang; Saulwood Lin; Gerhard Bohrmann (Frontiers in Marine Science, 2020)

Comparative transcriptome analysis reveals a gene expression profile that contributes to rhizome swelling in Panax japonicus var. major - Jun Rong Tang; Ying Chun Lu; Zheng Jie Gao; Wan Ling Song; Kun Hua Wei; Yan Zhao; Qing Yan Tang; Xue Jiao Li; Jun Wen Chen; Guang Hui Zhang; Guang Qiang Long; Wei Fan; et al. (Plant Biosystems, 2020)

High-level soluble expression of human Cu,Zn superoxide dismutase with high activity in Escherichia coli - Jin-Ling Yang; Xing-Lun Li; Feng-Lin Jiang; Ting Gong; Jing-Jing Chen; Tian-Jiao Chen; Ping Zhu (World Journal of Microbiology and Biotechnology, 2020)

Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort - Wei-Wei Li; Zhen Wang; Dong-Yu Fan; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Ling Li; Heng Yang; Yu-Hui Liu; Xian-Le Bu; Wang-Sheng Jin; Fan Zeng; et al. (Neuroscience Bulletin, 2020)

Targeting Inflammation, PHA-767491 Shows a Broad Spectrum in Protein Aggregation Diseases - Yu-Han Chung; Chia-Wei Lin; Hsin-Yu Huang; Shu-Ling Chen; Hei-Jen Huang; Ying-Chieh Sun; Guan-Chiun Lee; Guey-Jen Lee-Chen; Ya-Ching Chang; Hsiu Mei Hsieh-Li (Journal of Molecular Neuroscience, 2020)

MicroRNA-153-3p enhances the sensitivity of chronic myeloid leukemia cells to imatinib by inhibiting B-cell lymphoma-2-mediated autophagy - Yu-Ling Li; Jia-Ming Tang; Xiao-Yun Chen; Bing Luo; Guo-Hua Liang; Qian Qu; Zi-Yuan Lu (Human Cell, 2020)

Correction to: Intra-host diversity of hepatitis B virus during mother-to-child transmission: the X gene may play a key role in virus survival in children after transmission - Yanjie Li; Chenguang Shen; Liuqing Yang; Yang Yang; Miao Wang; Shanqin Li; Feng Chen; Min Yang; Ling Peng; Jinmin Ma; Zhongping Duan; Liqiang Li; et al. (Archives of Virology, 2020)

Genome-Wide Analysis of NAC Transcription Factors and Characterization of the Cold Stress Response in Sweet Osmanthus - Yuanzheng Yue; Ling Li; Yuli Li; Haiyan Li; Wenjie Ding; Tingting Shi; Gongwei Chen; Xiulian Yang; Lianggui Wang (Plant Molecular Biology Reporter, 2020)

Identification of PP2A and S6 Kinase as Modifiers of Leucine-Rich Repeat Kinase-Induced Neurotoxicity - Joan Poh Ling Sim; Wang Ziyin; Adeline Henry Basil; Shuping Lin; Zhongcan Chen; Chengwu Zhang; Li Zeng; Yu Cai; Kah-Leong Lim (NeuroMolecular Medicine, 2020)
Mutations in LRRK2 are currently recognized as the most common monogenetic cause of Parkinsonism. The elevation of kinase activity of LRRK2 that frequently accompanies its mutations is widely thought to contribute to its toxicity. Accordingly, many groups have developed LRRK2-specific kinase inhibitors as a potential therapeutic strategy. Given that protein phosphorylation is a reversible event, we sought to elucidate the phosphatase(s) that can reverse LRRK2-mediated phosphorylation, with the view that targeting this phosphatase(s) may similarly be beneficial. Using an unbiased RNAi phosphatase screen conducted in a Drosophila LRRK2 model, we identified PP2A as a genetic modulator of LRRK2-induced neurotoxicity. Further, we also identified ribosomal S6 kinase (S6K), a target of PP2A, as a novel regulator of LRRK2 function. Finally, we showed that modulation of PP2A or S6K activities ameliorates LRRK2-associated disease phenotype in Drosophila .

Genome-Wide Analysis of LAZ1 Gene Family from Maize - Bing Liang Liu; Hao Qiang Yu; Qian Wen; Feng Ling Fu; Wan Chen Li (Journal of Plant Growth Regulation, 2020)

Cognitive Load of Exercise Influences Cognition and Neuroplasticity of Healthy Elderly: An Exploratory Investigation - Yi-Ping Chao; Changwei W. Wu; Li-Jung Lin; Cheng-Hung Lai; Hong-Yi Wu; Ai-Ling Hsu; Chiao-Nan Chen (Journal of Medical and Biological Engineering, 2020)
This study explored the effects of exercise with either high cognitive load or low cognitive load on cognitive performance and neuroplasticity in healthy elderly. Twenty-eight sedentary community-dwelling seniors participated in this study. Participants were assigned to one of three groups: the control group (C), low-cognitive load exercise group (LE), or high-cognitive load exercise group (HE). Individuals in both exercise groups engaged in moderate-intensity aerobic exercise for 4 months. Resting-state functional MRI and diffusion MRI were used to investigate the effects of intervention on functional and structural connectivity, respectively. Analysis of covariance with baseline, age and the education year as covariates was used to determine the effects of intervention. We found 4 months of exercise with high-cognitive load, but not exercise with low-cognitive load, improved the overall cognitive function of healthy elderly. Additionally, the HE group showed increased resting-state functional connectivity of superior frontal gyrus and anterior cingulate cortex and decreased functional connectivity of middle occipital gyrus and postcentral gyrus. The age-related alterations in local efficiency and betweenness were protected by exercise. Our findings might suggest that exercise with greater cognitive load likely results in greater training effects on cognition and brain connectivity than exercise requiring lower cognitive loads for healthy elderly.

Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China - Cheng-yi Lin; Die Li; Jie-ming Lu; Zhe-bin Yu; Yao Zhu; Peng Shen; Meng-ling Tang; Ming-juan Jin; Hong-bo Lin; Li-ming Shui; Kun Chen; Jian-bing Wang (Environmental Science and Pollution Research, 2020)

Molecular evolution of GII.P17-GII.17 norovirus associated with sporadic acute gastroenteritis cases during 2013–2018 in Zhoushan Islands, China - Can Chen; Bing Wu; Hui Zhang; Ke-Feng Li; Rong Liu; Hong-Ling Wang; Jian-Bo Yan (Virus Genes, 2020)

Assessing the effects of payments for ecosystem services programs on forest structure and species biodiversity - Hsiang Ling Chen; Rebecca L. Lewison; Li An; Yu Hsin Tsai; Douglas Stow; Lei Shi; Shuang Yang (Biodiversity and Conservation, 2020)
Globally, biodiversity has declined at an unprecedented rate, challenging the viability of ecosystems, species, and ecological functions and their corresponding services. Payments for ecosystem services (PES) programs have been established and implemented worldwide to combat the degradation or loss of essential ecosystems and ecosystem services without sacrificing the well-being of people. With an overarching goal of reducing soil erosion, China’s Grain-to-Green program (GTGP) converts cropland to forest or grassland. As one of the largest PES programs in the world, GTGP has great potential to offer biodiversity conservation co-benefits. To consider how GTGP may influence biodiversity, we measured forest structure and plant and wildlife species diversity at both GTGP forest and natural forest sites in Fangjingshan National Nature Reserve, China. We also evaluated the relationship between canopy cover and biodiversity measures to test whether forest cover, the most commonly measured and reported ecological metric of PES programs, might act as a good proxy for other biodiversity related parameters. We found that forest cover and species diversity increased after GTGP implementation as understory and overstory plant cover, and understory and midstory plant diversity at GTGP sites were similar to natural forest. Our results suggest that GTGP may also have been associated with increased habitat for protected and vulnerable wildlife species including Elliot’s pheasant ( Syrmaticus ellioti ), hog badger ( Arctonyx collaris ), and wild boar ( Sus scrofa ). Nevertheless, we identified key differences between GTGP forest and natural forest, particularly variation in forest types and heterogeneity of overstory vegetation. As a result, plant overstory diversity and wildlife species richness at GTGP forest were significantly lower than at natural forest. Our findings suggest, while forest cover may be a good proxy for some metrics of forest structure, it does not serve as a robust proxy for many biodiversity parameters. These findings highlight the need for and importance of robust and representative indicators or proxy variables for measuring ecological effects of PES programs on compositional and structural diversity. We demonstrate that PES may lead to biodiversity co-benefits, but changes in program implementation could improve the return on investment of PES programs to support conservation of biodiversity.

Intra-host diversity of hepatitis B virus during mother-to-child transmission: the X gene may play a key role in virus survival in children after transmission - Yanjie Li; Chenguang Shen; Liuqing Yang; Yang Yang; Miao Wang; Shanqin Li; Feng Chen; Min Yang; Ling Peng; Jinmin Ma; Zhongping Duan; Liqiang Li; et al. (Archives of Virology, 2020)

Plastic pollution in croplands threatens long‐term food security - Dan Zhang; Ee Ling Ng; Wanli Hu; Hongyuan Wang; Pablo Galaviz; Hude Yang; Wentao Sun; Chongxiao Li; Xingwang Ma; Bin Fu; Peiyi Zhao; Fulin Zhang; et al. (Global Change Biology, 2020)
Plastic pollution is a global concern given its prevalence in aquatic and terrestrial ecosystems. Studies have been conducted on the distribution and impact of plastic pollution in marine ecosystems, but little is known on terrestrial ecosystems. Plastic mulch has been widely used to increase crop yields worldwide, yet the impact of plastic residues in cropland soils to soil health and crop production in the long term remained unclear. In this paper, using a global meta‐analysis, we found that the use of plastic mulch can indeed increase crop yields on average by 25%–42% in the immediate season due to the increase of soil temperature (+8%) and moisture (+17%). However, the unabated accumulation of film residues in the field negatively impacts its physicochemical properties linked to healthy soil and threatens food production in the long term. It has multiple negative impacts on plant growth including crop yield (at the mean rate of −3% for every additional 100 kg/ha of film residue), plant height (−2%) and root weight (−5%), and soil properties including soil water evaporation capacity (−2%), soil water infiltration rate (−8%), soil organic matter (−0.8%) and soil available phosphorus (−5%) based on meta‐regression. Using a nationwide field survey of China, the largest user of plastic mulch worldwide, we found that plastic residue accumulation in cropland soils has reached 550,800 tonnes, with an estimated 6%–10% reduction in cotton yield in some polluted sites based on current level of plastic residue content. Immediate actions should be taken to ensure the recovery of plastic film mulch and limit further increase in film residue loading to maintain the sustainability of these croplands.

Tracing mantle sources in the northern Lau back-arc basin by independent component analysis of basalt isotopic compositions - Xichang Wu; Liyan Tian; Xuan-Ce Wang; Fengyou Chu; Quanshu Yan; Fengyue Sun; Xiaohu Li; Wei Wang; Luyao Yu; Zhenggang Li; Ling Chen (International Geology Review, 2020)

Identification and characterization of two morphologically distinct stem cell subpopulations from human urine samples - An-Jing Chen; Jin-Kui Pi; Jun-Gen Hu; Yi-Zhou Huang; Hong-Wei Gao; Sheng-Fu Li; Jesse Li-Ling; Hui-Qi Xie (Science China Life Sciences, 2020)

Effects of carbon source addition on microbial community and water quality in recirculating aquaculture systems for Litopenaeus vannamei - Zhao Chen; Zhiqiang Chang; Long Zhang; Jiajia Wang; Ling Qiao; Xiefa Song; Jian Li (Fisheries Science, 2020)

Brain-Wide Shape Reconstruction of a Traced Neuron Using the Convex Image Segmentation Method - Shiwei Li; Tingwei Quan; Hang Zhou; Qing Huang; Tao Guan; Yijun Chen; Cheng Xu; Hongtao Kang; Anan Li; Ling Fu; Qingming Luo; Hui Gong; et al. (Neuroinformatics, 2020)

High-carbohydrate diet promotes the adaptation to acute hypoxia in zebrafish - Qiang Ma; Chun-Ting Hu; Junjiayu Yue; Yuan Luo; Fang Qiao; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2020)

Coix seed oil prolongs lifespan and enhances stress resistance in Caenorhabditis elegans - Xin-Yan Chen; De-Chun Liao; Ying-Ting Yu; Cong-Min Wei; Ling-Yan Xuan; Shan Li; Hong-Bing Wang (Biogerontology, 2020)

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury - Yingxia Liu; Yang Yang; Cong Zhang; Fengming Huang; Fuxiang Wang; Jing Yuan; Zhaoqin Wang; Jinxiu Li; Jianming Li; Cheng Feng; Zheng Zhang; Lifei Wang; et al. (Science China Life Sciences, 2020)

ABA and sucrose co-regulate strawberry fruit ripening and show inhibition of glycolysis - Ya Luo; Cong Ge; Yajie Ling; Fan Mo; Min Yang; Leiyu Jiang; Qing Chen; Yuanxiu Lin; Bo Sun; Yong Zhang; Yan Wang; Mengyao Li; et al. (Molecular Genetics and Genomics, 2020)

Comparative study on the bioaccumulation of lead, cadmium and nickel and their toxic effects on the growth and enzyme defence strategies of a heavy metal accumulator, Hydrilla verticillata (L.f.) Royle - Hong Zhang; Ling-Lei Zhang; Jia Li; Min Chen; Rui-Dong An (Environmental Science and Pollution Research, 2020)

Mapping landslide susceptibility at the Three Gorges Reservoir, China, using gradient boosting decision tree, random forest and information value models - Tao Chen; Li Zhu; Rui-qing Niu; C John Trinder; Ling Peng; Tao Lei (Journal of Mountain Science, 2020)

A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus - Yan Wang; Xuejiao Cui; Xu Chen; Shixing Yang; Yu Ling; Qianben Song; Su Zhu; Luying Sun; Chuang Li; Yu Li; Xutao Deng; Eric Delwart; et al. (Archives of Virology, 2020)

The protective effect of Geniposide on diabetic cognitive impairment through BTK/TLR4/NF-κB pathway - Shengnan Liu; Menglin Zheng; Yixuan Li; Ling He; Tong Chen (Psychopharmacology, 2020)

Utilization of pre-existing competent and barren quartz veins as hosts to later orogenic gold ores at Huangjindong gold deposit, Jiangnan Orogen, southern China - Liang Zhang; David I. Groves; Li-Qiang Yang; Si-Chen Sun; Roberto F. Weinberg; Jiu-Yi Wang; Sheng-Gang Wu; Lei Gao; Lan-Ling Yuan; Rong-Hua Li (Mineralium Deposita, 2020)

The expression and role of PIDD in retina after optic nerve crush - Fen Tang; Fan Xu; Ling Cui; Wei Huang; Li Jiang; Lifei Chen; Wenya Yan; Wenjing He; Chaolan Shen; Hui Huang; Jian Lv; Xin Zhao; et al. (Journal of Molecular Histology, 2020)

Pharmacokinetics of and maintenance dose recommendations for vancomycin in severe pneumonia patients undergoing continuous venovenous hemofiltration with the combination of predilution and postdilution - Qiang Li; Fenghua Liang; Ling Sang; Pengpeng Li; Bijun Lv; Lu Tan; Xiaoqing Liu; Wenying Chen (European Journal of Clinical Pharmacology, 2020)

Agrobacterium-mediated genetic transformation of Chinese chestnut (Castanea mollissima Blume) - Zhi-lin Sun; Xiao Li; Wan Zhou; Jun-di Yan; Yue-rong Gao; Xiao-wei Li; Jia-chen Sun; Ke-feng Fang; Qing Zhang; Yu Xing; Ling Qin; Qing-qin Cao (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)
Chinese chestnut ( Castanea mollissima ) is an important germplasm resource for the breeding of Castanea species worldwide with vital ecological and economic value. Biotechnology overcomes the limitations of traditional breeding and accelerates germplasm improvement. However, a genetic transformation system for Chinese chestnut has not yet been established. In this study, a stable and efficient Agrobacterium -mediated genetic transformation method for Chinese chestnut is described. Embryogenic calli of C. mollissima cv. ‘Yanshanhongli’ were used as the target material. The sensitivity of embryogenic calli to kanamycin was determined, whereby the proliferation of non-transformed calli was completely inhibited at 180 mg/L. Antibiotic inhibition results for Chinese chestnut embryogenic calli showed that 50 mg/L cefotaxime and 500 μM timentin completely inhibited the growth of Agrobacterium tumefaciens but did not affect the normal growth of Chinese chestnut embryogenic calli. When embryogenic calli were co-cultured for 2 days with Agrobacterium tumefaciens strain AGL1 harboring the PBI121-EGFP plasmid, an embryogenic callus transformation efficiency of 4.55% was obtained, and two transgenic chimera were acquired. This Agrobacterium -mediated transformation system for Chinese chestnut provides a fundamental platform for genetic improvement of core germplasm and for further verification of gene function.

Hirsutella sinensis inhibits NLRP3 inflammasome activation to block aristolochic acid-induced renal tubular epithelial cell transdifferentiation - Min Yu; Yu-lin Man; Meng-hua Chen; Li-hua Wu; Yi Zhou; Xiao-ling Zhou; Na Chen; Rui Ma; Li-na Sun (Human Cell, 2020)

Cytological, genetic, and proteomic analysis of a sesame (Sesamum indicum L.) mutant Siyl-1 with yellow–green leaf color - Tong-Mei Gao; Shuang-Ling Wei; Jing Chen; Yin Wu; Feng Li; Li-Bin Wei; Chun Li; Yan-Juan Zeng; Yuan Tian; Dong-Yong Wang; Hai-Yang Zhang (Genes & Genomics, 2020)
Background Both photosynthetic pigments and chloroplasts in plant leaf cells play an important role in deciding on the photosynthetic capacity and efficiency in plants. Systematical investigating the regulatory mechanism of chloroplast development and chlorophyll (Chl) content variation is necessary for clarifying the photosynthesis mechanism for crops. Objective This study aims to explore the critical regulatory mechanism of leaf color mutation in a yellow–green leaf sesame mutant Siyl - 1 . Methods We performed the genetic analysis of the yellow-green leaf color mutation using the F 2 population of the mutant Siyl - 1 . We compared the morphological structure of the chloroplasts, chlorophyll content of the three genotypes of the mutant F 2 progeny. We performed the two-dimensional gel electrophoresis (2-DE) and compared the protein expression variation between the mutant progeny and the wild type. Results Genetic analysis indicated that there were 3 phenotypes of the F 2 population of the mutant Siyl - 1 , i.e., YY type with light-yellow leaf color (lethal); Yy type with yellow-green leaf color, and yy type with normal green leaf color. The yellow-green mutation was controlled by an incompletely dominant nuclear gene, Siyl - 1 . Compared with the wild genotype, the chloroplast number and the morphological structure in YY and Yy mutant lines varied evidently. The chlorophyll content also significantly decreased ( P < 0.05 ). The 2-DE comparison showed that there were 98 differentially expressed proteins (DEPs) among YY, Yy, and yy lines. All the 98 DEPs were classified into 5 functional groups. Of which 82.7% DEPs proteins belonged to the photosynthesis and energy metabolism group. Conclusion The results revealed the genetic character of yellow-green leaf color mutant Siyl - 1 . 98 DEPs were found in YY and Yy mutant compared with the wild genotype. The regulation pathway related with the yellow leaf trait mutation in sesame was analyzed for the first time. The findings supplied the basic theoretical and gene basis for leaf color and chloroplast development mechanism in sesame.

Fishing for feed in China: Facts, impacts and implications - Wenbo Zhang; Min Liu; Yvonne Sadovy de Mitcheson; Ling Cao; Duncan Leadbitter; Richard Newton; David C. Little; Songlin Li; Yi Yang; Xiao Chen; Wei Zhou (Fish and Fisheries, 2020)
China is the world's largest capture fisheries and aquaculture producer. Over recent decades, China's domestic marine catch composition has changed markedly, from large volumes of a few high‐valued food species to multiple, small, low‐valued, species, a significant proportion of which is primarily used as animal, especially fish, feed. Despite the growing volume and economic importance of the feed catches, their species composition, catch volumes and socio‐environmental impacts are all poorly understood. Based on a nationwide survey of >800 fishing vessels, and the identification and measurement of >12,000 fish and invertebrate individuals, the present study provides an overview of the feed component of China's domestic marine catch, by volumes, species and sizes, and found it to be substantial and biologically unsustainable. Half of the trawler catch (3 million metric tons, mmt), or 35% of the total catch (4.6 mmt) in China's exclusive economic zone, are now comprised of low‐valued “feed‐grade fish”. The present study identified 218 fish species, 50 crustaceans and five cephalopods, and of these, 102 fish species were food species with 89% individuals in their juvenile size ranges. Feed‐grade fish were mainly used as aquaculture feed directly, or indirectly, through the feed industry after reduction to fishmeal and fish oil. The unparalleled scale and poor fisheries resource condition of China's domestic marine fisheries, in parallel with severe overfishing of juveniles, creates a demand for fundamental changes to fishery management practices, including a significant reduction of fishing effort to ensure productivity and ecosystem resilience.

Identification and Expression Pattern Analysis of Bacterial Blight Resistance Genes in Oryza officinalis Wall ex Watt Under Xanthomonas oryzae Pv. oryzae Stress - Chunmiao Jiang; Suqin Xiao; Dingqin Li; Ling Chen; Qiaofang Zhong; Fuyou Yin; Tengqiong Yu; Xue Ke; Dunyu Zhang; Jian Fu; Yue Chen; Bo Wang; et al. (Plant Molecular Biology Reporter, 2019)
Background Bacterial blight (BB) caused by Xanthomonas oryzae Pv. oryzae ( Xoo ) is one of the most serious diseases of rice worldwide. Oryza officinalis Wall ex Watt, harboring abundant genetic diversity and disease resistance features, are important resources of exploring resistance genes with broad-spectrum resistance to BB. However, the molecular mechanisms and genes of BB resistance in O. officinalis have been rarely explored. Results Here, the BB resistance of four different origin O. officinalis populations in Yunnan were identified by seven representative hypervirulent Xoo races, which exhibited different BB resistance among four populations, in which the BB resistance of the Gengma_Lincang population was the strongest. In addition, the pathogenetic ability of seven Xoo races to O. officinalis was different in that the pathogenicity of PXO99 was stronger than that of C5. There were no remarkable differences in leaf microstructures among four O. officinalis populations, revealing the differences in resistance of four O. officinalis to BB are caused by the endogenous resistance genes. Furthermore, our results proved that there were no nine cloned BB resistance genes in four populations but possessed dominant Xa5 , dominant Xa13 , and recessive xa3/xa26 homologous alleles of xa5 , xa13 , and Xa3 / Xa26 resistance genes. These three homologous genes were isolated and cloned from four populations and named OoXa5 , OoXa13 , and Ooxa3 / xa26 . The expression profile revealed that the expression levels of OoXa13 and Ooxa3/xa26 were significantly down-regulated under PXO99 and C5 stress, especially in the Gengma_Lincang population, suggesting the O. officinalis might enhance BB resistance by down-regulating the expression level of OoXa13 and Ooxa3 / xa26 . Conclusion The BB resistance genes of O. officinalis had its own characteristics by expression pattern and BLAST analysis of OoXa5 , OoXa13 , and Ooxa3 / xa26 , which indicated that there might be new genes or molecular mechanism of BB resistance in O. officinalis. Our studies provided a solid foundation and reference for revealing the molecular mechanism of BB resistance in O. officinalis .

Stabilization of hydrophobic organic contaminants in sediments by natural zeolites: bioavailability-based assessment of efficacy using equilibrium passive sampling - Yiqin Chen; Wenjian Yu; Ling Jin; Qian Wang; Jie Yin; Jianwei Lin; Juan-Ying Li (Journal of Soils and Sediments, 2019)

Multi‐model analysis of climate impacts on plant photosynthesis in China during 2000–2015 - Hao Yan; Shao‐Qiang Wang; Jun‐Bang Wang; Yun Cao; Ling‐Ling Xu; Men‐Xin Wu; Lu Cheng; Liu‐Xi Mao; Feng‐Hua Zhao; Xian‐Zhou Zhang; Yun‐Fen Liu; Yan‐Fen Wang; et al. (International Journal of Climatology, 2019)
Differences, arising from differences in gross primary production (GPP) model structures and driving forces, have fuelled arguments concerning interannual changes of GPP in China since 2000. To better investigate the interannual variability of GPP and its covariance with climate factors in China, this study adopted a multi‐model analysis based on three GPP models (i.e., Terrestrial Ecosystem Carbon flux model [TEC], Breathing Earth System Simulator model [BESS], and MOD17 GPP model). The results show that annual GPP in China increased by 0.021–0.057 Pg C year −1 from 2000 to 2015 attributable to atmospheric‐CO 2 fertilization effects and favourable climate change, that is, increasing precipitation ( P r ) and temperature ( T a ). However, northern China and southern China had a large difference in the amplitude of these GPP changes; annual GPP increased by 0.017–0.039 Pg C year −1 in northern China but only 0.001–0.018 Pg C year −1 in southern China. Northern China and southern China occupy contrasting climate zones and this contrast produced different interannual variability of GPP through different mechanisms. Northern China has a dry climate with GPP changes sensitive to P r . As a result, more P r along with higher T a in northern China produced the strong uptrend of GPP from 2000 to 2015. In contrast, southern China has a wet climate with its GPP sensitive to solar radiation and T a . For the interval of 2000–2015, decreasing radiation plus drought exerted a negative influence on GPP in southern China. This study highlights the diverse mechanisms in which climate change affects GPP in dry and wet climate zones. A robust multi‐model analysis is preferred to reduce uncertainties arising from a single GPP model and its driving data.

Permanent disappearance and seasonal fluctuation of urban lake area in Wuhan, China monitored with long time series remotely sensed images from 1987 to 2016 - Lingfei Shi; Feng Ling; Giles M Foody; Cheng Chen; Shiming Fang; Xiaodong Li; Yihang Zhang; Yun Du (International Journal of Remote Sensing, 2019)

The metabolic regulation of dietary L‐carnitine in aquaculture nutrition: present status and future research strategies - Ling‐Yu Li; Samwel M. Limbu; Qiang Ma; Li‐Qiao Chen; Mei‐Ling Zhang; Zhen‐Yu Du (Reviews in Aquaculture, 2019)
L‐carnitine is a multi‐functional nutrient which plays a leading role in fatty acid metabolism in mammals and other eukaryotes. Its main physiological function is to promote fatty acid β‐oxidation to produce energy, which reduces body fat content and improves body weight without affecting moisture content in whole body and muscle. In recent years, its dietary supplementation in aquaculture nutrition has been studied in different cultured species. It has been proved that L‐carnitine can improve growth and increase lipid utilization rate in some aquatic animals. However, such beneficial effects of dietary L‐carnitine are limited or absent in other species. The reasons for the conflicting results obtained on L‐carnitine functions in aquatic animals need to be elucidated. This review explores comprehensively the different physiological functions of L‐carnitine in various aquatic animals. In the end, research strategies are provided to elucidate the existing conflicts on dietary L‐carnitine application in aquaculture nutrition in order to promote its utilization in aquatic feed industry.

Three new labdane-type diterpenoids from Callicarpa macrophylla Vahl. - Zhen-Hui Wang; Huan-Jun Xu; Yang-Yang Zhai; Lan-Ping Yang; Qiang Li; Mei Huang; Xing-Ying Chen; Wen-Kui Zhang; Yue-Li Meng; Qing-Ling Zhang; Chao Niu; Yan-Ru Zhang (Natural Product Research, 2019)

Indication of dynamic neurovascular coupling from inconsistency between EEG and fMRI indices across sleep–wake states - Changwei W. Wu; Pei-Jung Tsai; Sharon Chia-Ju Chen; Chia-Wei Li; Ai-Ling Hsu; Hong-Yi Wu; Yu-Ting Ko; Pai-Chuan Hung; Chun-Yen Chang; Ching-Po Lin; Timothy J. Lane; Chia-Yuen Chen (Sleep and Biological Rhythms, 2019)

Two-factor ANOVA of SSH and RNA-seq analysis reveal development-associated Pi-starvation genes in oilseed rape - Zhong-Wei Zhang; Ling-Yang Feng; Jian-Hui Wang; Yu-Fan Fu; Xin Cai; Chang-Quan Wang; Jun-Bo Du; Ming Yuan; Yang-Er Chen; Pei-Zhou Xu; Ting Lan; Guang-Deng Chen; et al. (Planta, 2019)

Association of the Polygenic Risk Score with the Incidence Risk of Parkinson’s Disease and Cerebrospinal Fluid α-Synuclein in a Chinese Cohort - Wei-Wei Li; Dong-Yu Fan; Ying-Ying Shen; Fa-Ying Zhou; Yang Chen; Ye-Ran Wang; Heng Yang; Jing Mei; Ling Li; Zhi-Qiang Xu; Yan-Jiang Wang (Neurotoxicity Research, 2019)

Serratia microhaemolytica sp. nov., isolated from an artificial lake in Southern China - Juan Wang; Min-Ling Zheng; Jian-Yu Jiao; Wei-Jia Wang; Shuai Li; Min Xiao; Cha Chen; Ping-Hua Qu; Wen-Jun Li (Antonie van Leeuwenhoek, 2019)

Correction to: Occurrence of polybrominated diphenyl ethers in floor and elevated surface house dust from Shanghai, China - Dong Niu; Yanling Qiu; Li Li; Yihui Zhou; Xinyu Du; Zhiliang Zhu; Ling Chen; Zhifen Lin (Environmental Science and Pollution Research, 2019)

Potential hypoglycemic effect of acetophenones from the root bark of Cynanchum wilfordii - Hao-Wen Jiang; Shan-Shan Gu; Lei Cao; Sheng-Shi Jiang; Jing Lin; Yan Chen; Ling Wang; He Jiao; Jing-Ya Li; Wei-Min Zhao; Jin-Long Li (Natural Product Research, 2019)

RNA-Seq-based transcriptomic profiling of primary interstitial cells of Cajal in response to bovine viral diarrhea virus infection - Shengnan Li; Xinyan Hu; Ruixin Tian; Yanting Guo; Junzhen Chen; Zhen Li; Xinyan Zhao; Ling Kuang; Duoliang Ran; Hongqiong Zhao; Xiaohong Zhang; Jinquan Wang; et al. (Veterinary Research Communications, 2019)

Genetic diversity of ten black walnut (Juglans nigra L.) cultivars and construction of a mapping population - S. Jacob Schneider; Anna Y. Hwang; Sadie D. Land; Li-Ling Chen; Andrew L. Thomas; Chin-Feng Hwang (Tree Genetics & Genomes, 2019)

Correction to: In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrPV180I Mutation - Zerui Wang; Jue Yuan; Pingping Shen; Romany Abskharon; Yue Lang; Johnny Dang; Alise Adornato; Ling Xu; Jiafeng Chen; Jiachun Feng; Mohammed Moudjou; Tetsuyuki Kitamoto; et al. (Molecular Neurobiology, 2019)

In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrPV180I Mutation - Zerui Wang; Jue Yuan; Pingping Shen; Romany Abskharon; Yue Lang; Johnny Dang; Alise Adornato; Ling Xu; Jiafeng Chen; Jiachun Feng; Mohammed Moudjou; Tetsuyuki Kitamoto; et al. (Molecular Neurobiology, 2019)

Population Genetics of Calotropis gigantea, a Medicinal and Fiber Resource Plant, as Inferred from Microsatellite Marker Variation in two Native Countries - Md. Rabiul Islam; Zhi-Zhong Li; Andrew W. Gichira; Mohammad Nur Alam; Peng-Cheng Fu; Guang-Wan Hu; Qing-Feng Wang; Ling-Yun Chen (Biochemical Genetics, 2019)

A novel QTL QTrl.saw-2D.2 associated with the total root length identified by linkage and association analyses in wheat (Triticum aestivum L.) - Xingwei Zheng; Xiaojie Wen; Ling Qiao; Jiajia Zhao; Xiaojun Zhang; Xin Li; Shuwei Zhang; Zujun Yang; Zhijian Chang; Jianli Chen; Jun Zheng (Planta, 2019)

Geodynamic transition from subduction to extension: evidence from the geochronology and geochemistry of granitoids in the Sangsang area, southern Lhasa Terrane, Tibet - Feng Huang; Mingjian Li; Jifeng Xu; Yunchuan Zeng; Jianlin Chen; Baodi Wang; Hongxia Yu; Ling Chen; Peipei Zhao; Zhao Zhang (International Journal of Earth Sciences, 2019)

Heavy metals and PAHs in an open fishing area of the East China Sea: Multimedia distribution, source diagnosis, and dietary risk assessment - Qian Wang; Fei Peng; Yiqin Chen; Ling Jin; Jun Lin; Xu Zhao; Jie Yin; Juan-Ying Li (Environmental Science and Pollution Research, 2019)

Blood and seminal plasma mercury levels and predatory fish intake in relation to low semen quality - Chin-En Ai; Ching-Jen Li; Ming-Chien Tsou; Jun-Lin Chen; Hsing-Cheng Hsi; Ling-Chu Chien (Environmental Science and Pollution Research, 2019)

Geochemistry of peridotites from the Yap Trench, Western Pacific: implications for subduction zone mantle evolution - Ling Chen; Limei Tang; Xiaohu Li; Yanhui Dong; Xing Yu; Weiwei Ding (International Geology Review, 2019)

PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model - Ching-Chi Chiu; Chin-Song Lu; Yi-Hsin Weng; Ying-Ling Chen; Ying-Zu Huang; Rou-Shayn Chen; Yi-Chuan Cheng; Yin-Cheng Huang; Yu-Chuan Liu; Szu-Chia Lai; Kun-Jun Lin; Yan-Wei Lin; et al. (Molecular Neurobiology, 2019)

Temporal–spatial distribution of synthetic pyrethroids in overlying water and surface sediments in Guangzhou waterways: potential input mechanisms and ecological risk to aquatic systems - Wen-Gai Li; De-Yin Huang; Dong Chen; Cong Wang; Gao-Ling Wei (Environmental Science and Pollution Research, 2019)

Predicting the cytotoxicity of disinfection by-products to Chinese hamster ovary by using linear quantitative structure–activity relationship models - Li-Tang Qin; Xin Zhang; Yu-Han Chen; Ling-Yun Mo; Hong-Hu Zeng; Yan-Peng Liang; Hua Lin; Dun-Qiu Wang (Environmental Science and Pollution Research, 2019)

A novel phage from periodontal pockets associated with chronic periodontitis - Yu Zhang; Tong-Ling Shan; Fei Li; Tian Yu; Xi Chen; Xu-Tao Deng; Eric Delwart; Xi-Ping Feng (Virus Genes, 2019)

Pseudofrancisella aestuarii gen. nov., sp. nov., a novel member of the family Francisellaceae isolated from estuarine seawater - Min-Ling Zheng; Jian-Yu Jiao; Lei Dong; Ming-Xian Han; Liang-Hui Li; Min Xiao; Cha Chen; Ping-Hua Qu; Wen-Jun Li (Antonie van Leeuwenhoek, 2019)

New pyrazinoquinazoline alkaloids Isolated from a culture of Stenotrophomonas maltophilia QB-77 - Sheng-Yan Qian; Cai-Ling Yang; Afsar Khan; Rong-Xiang Chen; Ming-Song Wu; Li Tuo; Qian Wang; Jian-Guo Liu; Gui-Guang Cheng (Natural Product Research, 2019)

Apple AP2/EREBP transcription factor MdSHINE2 confers drought resistance by regulating wax biosynthesis - Ya-Li Zhang; Chun-Ling Zhang; Gui-Luan Wang; Yong-Xu Wang; Chen-Hui Qi; Chun-Xiang You; Yuan-Yuan Li; Yu-Jin Hao (Planta, 2019)

Early heading 7 interacts with DTH8, and regulates flowering time in rice - Maohong Cai; Saihua Chen; Mingming Wu; Tianhui Zheng; Liang Zhou; Chaonan Li; Huan Zhang; Jiachang Wang; Xinyang Xu; Juntao Chai; Yulong Ren; Xiuping Guo; et al. (Plant Cell Reports, 2019)

Sodium Fluoride (NaF) Induces Inflammatory Responses Via Activating MAPKs/NF-κB Signaling Pathway and Reducing Anti-inflammatory Cytokine Expression in the Mouse Liver - Linlin Chen; Ping Kuang; Huan Liu; Qin Wei; Hengmin Cui; Jing Fang; Zhicai Zuo; Junliang Deng; Yinglun Li; Xun Wang; Ling Zhao (Biological Trace Element Research, 2019)

Dynamics of physiological and miRNA changes after long-term proliferation in somatic embryogenesis of Picea balfouriana - Qingfen Li; Cheng Deng; Tianqing Zhu; Juanjuan Ling; Hanguo Zhang; Lisheng Kong; Shougong Zhang; Junhui Wang; Xiaoyang Chen (Trees, 2019)

Whole-genome analysis of the colonization-resistant bacterium Phytobacter sp. SCO41T isolated from Bacillus nematocida B16-fed adult Caenorhabditis elegans - Bowen Wang; Bingfen Huang; Junmei Chen; Wenpeng Li; Ling Yang; Lunguang Yao; Qiuhong Niu (Molecular Biology Reports, 2019)

Novel mutations in ZP1, ZP2, and ZP3 cause female infertility due to abnormal zona pellucida formation - Zhou Zhou; Caixia Ni; Ling Wu; Biaobang Chen; Yao Xu; Zhihua Zhang; Jian Mu; Bin Li; Zheng Yan; Jing Fu; Wenjing Wang; Lin Zhao; et al. (Human Genetics, 2019)

Ethyl lucidenates A reverses P-glycoprotein mediated vincristine resistance in K562/A02 cells - Peng Li; Shi-yu Chen; Shao-xin Shen; Ling-xue Liu; Jian-hua Xu; Zhi-qiang Zhang (Natural Product Research, 2019)

Relationship between polymorphisms of the lipid metabolism-related gene PLA2G16 and risk of colorectal cancer in the Chinese population - Xiao-Nv Xie; Jing Yu; Li-Hua Zhang; Zhi-Ying Luo; Dong-Sheng Ouyang; Ling-Jie Zheng; Chun-Yang Wang; Li Yang; Ling Chen; Zhi-Rong Tan (Functional & Integrative Genomics, 2019)

Novel mutation of type-1 insulin-like growth factor receptor (IGF-1R) gene in a severe short stature pedigree identified by targeted next-generation sequencing - Yu Yang; Hui Huang; Ka Chen; Li Yang; Li-ling Xie; Ting Xiong; Xian Wu (Journal of Genetics, 2019)

Socially controlled male‐to‐female sex reversal in the protogynous orange‐spotted grouper, Epinephelus coioides - Jiaxing Chen; Ling Xiao; Cheng Peng; Zhifeng Ye; Dengdong Wang; Yuqing Yang; Haifa Zhang; Mi Zhao; Shuisheng Li; Haoran Lin; Yong Zhang (Journal of Fish Biology, 2019)
Socially controlled sex change in teleosts is a dramatic example of adaptive reproductive plasticity. In many cases, the occurrence of sex change is triggered by a change in the social context, such as the disappearance of the dominant individual. The orange‐spotted grouper Epinephelus coioides is a typical protogynous hermaphrodite fish that changes sex from female to male and remains male throughout its life span. In this study, male‐to‐female sex reversal in male Epinephelus coioides was successfully induced by social isolation. The body length and mass, gonadal change, serum sex steroid hormone levels and sex‐related gene expression patterns during the process of socially controlled male‐to‐female sex reversal in E. coioides were systematically examined. This report investigates the physiological mechanisms of the socially controlled male‐to‐female sex reversal process in a protogynous hermaphrodite grouper species. The results enable us to study the physiological control of sex change, not only from female to male, but also from male to female.

Two new polyketides from the fungus Penicillium oxalicum MHZ153 - Yi Ren; Ling-Hui Chao; Jing Sun; Xiao-Nan Chen; Hui-Na Yao; Zhi-Xiang Zhu; Dan Dong; Ting Liu; Peng-Fei Tu; Jun Li (Natural Product Research, 2019)

Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice - Hei-Jen Huang; Shu-Ling Chen; Hsin-Yu Huang; Ying-Chieh Sun; Guan-Chiun Lee; Guey-Jen Lee-Chen; Hsiu Mei Hsieh-Li; Ming-Tsan Su (Psychopharmacology, 2019)

Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides - Qing-Yan Tang; Geng Chen; Wan-Ling Song; Wei Fan; Kun-Hua Wei; Si-Mei He; Guang-Hui Zhang; Jun-Rong Tang; Ying Li; Yuan Lin; Sheng-Chao Yang (Planta, 2019)

Complete genome analysis of a novel phage GW1 lysing Cronobacter - Haiyan Zeng; Wenjing He; Chengsi Li; Jumei Zhang; Na Ling; Yu Ding; Liang Xue; Moutong Chen; Haoming Wu; Qingping Wu (Archives of Virology, 2019)

Construction of a high-density linkage map and QTL detection of downy mildew resistance in Vitis aestivalis-derived ‘Norton’ - Surya Sapkota; Li-Ling Chen; Shanshan Yang; Katie E. Hyma; Lance Cadle-Davidson; Chin-Feng Hwang (Theoretical and Applied Genetics, 2019)

A Genome-Wide Association Study of α-Synuclein Levels in Cerebrospinal Fluid - Xiao-ling Zhong; Jie-Qiong Li; Li Sun; Ya-Qing Li; Hui-Fu Wang; Xi-Peng Cao; Chen-Chen Tan; Ling Wang; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2019)

Transcriptome characterization and SSR discovery in Squaliobarbus curriculus - Caijuan Li; Teng Teng; Fanfan Shen; Jinqiang Guo; Yining Chen; Chuankun Zhu; Qufei Ling (Journal of Oceanology and Limnology, 2019)

Identification of QTL regions for seedling root traits and their effect on nitrogen use efficiency in wheat (Triticum aestivum L.) - Xiaoli Fan; Wei Zhang; Na Zhang; Mei Chen; Shusong Zheng; Chunhua Zhao; Jie Han; Jiajia Liu; Xilan Zhang; Liqiang Song; Jun Ji; Xigang Liu; et al. (Theoretical and Applied Genetics, 2018)

Functions of PKS Genes in Lipid Synthesis of Schizochytrium sp. by Gene Disruption and Metabolomics Analysis - Zhipeng Li; Xi Chen; Jun Li; Tong Meng; Lingwei Wang; Zhen Chen; Yanyan Shi; Xueping Ling; Weiang Luo; Dafeng Liang; Yinghua Lu; Qingbiao Li; et al. (Marine Biotechnology, 2018)

AAV-Vectored Fms-Related Tyrosine Kinase 3 Ligand Inhibits CD34+ Progenitor Cell Engraftment in Humanized Mice - Lijun Ling; Xian Tang; Xiuyan Huang; Jingjing Li; Hui Wang; Zhiwei Chen (Journal of Neuroimmune Pharmacology, 2018)

Rhodanobacter ginsengiterrae sp. nov., an antagonistic bacterium against root rot fungal pathogen Fusarium solani, isolated from ginseng rhizospheric soil - Yue Huo; Jong-Pyo Kang; Jin-Kyu Park; Jinfeng Li; Ling Chen; Deok-Chun Yang (Archives of Microbiology, 2018)

Proteomic discovery of H2O2 response in roots and functional characterization of PutGLP gene from alkaligrass - Juanjuan Yu; Yongxue Zhang; Junming Liu; Lin Wang; Panpan Liu; Zepeng Yin; Siyi Guo; Jun Ma; Zhuang Lu; Tai Wang; Yimin She; Yuchen Miao; et al. (Planta, 2018)

Acute effect of fine and coarse particular matter on cardiovascular visits in Ningbo, China - Pei-wen Zheng; Peng Shen; Zhen-hua Ye; Zhen-yu Zhang; Peng-fei Chai; Die Li; Ming-juan Jin; Meng-Ling Tang; Huai-chu Lu; Hong-bo Lin; Jian-bing Wang; Kun Chen (Environmental Science and Pollution Research, 2018)

Isolation and purification of diterpenoids from the aerial parts of Isodon excisoides target-guided by UPLC-LTQ-Orbitrap-MS - Li-Ping Dai; Ling-Xia Zhang; Ya-Lin Liu; Hong Wu; Rui-Xin Liu; Meng Zhao; Shuang-Shuang Tian; Xue Jiang; Sui-Qing Chen (Natural Product Research, 2018)

Nitrogen additions reduce rhizospheric and heterotrophic respiration in a subtropical evergreen broad-leaved forest - Yong Peng; Guan-tao Chen; Shun Li; Hong-ling Hu; Ting-xing Hu; Li Liu; Yi Tang; Li-hua Tu (Plant and Soil, 2018)

Associations of HSP90AA2 gene polymorphisms with disease susceptibility, glucocorticoids efficacy and health-related quality of life in Chinese systemic lupus erythematosus patients - Man Zhang; Su-Su Li; Qiao-Mei Xie; Jian-Hua Xu; Xiu-Xiu Sun; Fa-Ming Pan; Sheng-Qian Xu; Sheng-Xiu Liu; Jin-Hui Tao; Shuang Liu; Jing Cai; Pei-Ling Chen; et al. (Genes & Genomics, 2018)

New podolactones from the seeds of Podocarpus nagi and their anti-inflammatory effect - Zhe-Ling Feng; Tian Zhang; Jing-Xin Liu; Xiu-Ping Chen; Li-She Gan; Yang Ye; Li-Gen Lin (Journal of Natural Medicines, 2018)

Fast 3D forward modeling of the magnetic field and gradient tensor on an undulated surface - Kun Li; Long-Wei Chen; Qing-Rui Chen; Shi-Kun Dai; Qian-Jiang Zhang; Dong-Dong Zhao; Jia-Xuan Ling (Applied Geophysics, 2018)

Source Contributions to PM2.5 under Unfavorable Weather Conditions in Guangzhou City, China - Nan Wang; Zhenhao Ling; Xuejiao Deng; Tao Deng; Xiaopu Lyu; Tingyuan Li; Xiaorong Gao; Xi Chen (Advances in Atmospheric Sciences, 2018)

The lncRNA MIR4435-2HG promotes lung cancer progression by activating β-catenin signalling - Haiyun Qian; Li Chen; Jiangping Huang; Xianghui Wang; Shengwei Ma; Fenghe Cui; Liyun Luo; Li Ling; Kai Luo; Guopei Zheng (Journal of Molecular Medicine, 2018)