High-throughput creation of Nicotiana tabacum gene-targeted mutants based on CRISPR/Cas9 - Yudong Chen; Haiying Xiang; Ling Jia; Qianxu Yang; Jianduo Zhang; Jiarui Jiang; Wanli Zeng; Lele Deng; Jingjing Jin; Qian Gao; Xuemei Li (Plant Cell Reports, 2023)

Strength, deformation and failure behavior of bolted rock-like specimen with multiple cracks under uniaxial compression by particle flow simulation - Wendong Yang; Yiwei Li; Ling Wang; Kaicheng Zhang; Zhicheng Gong (Geosciences Journal, 2023)

Transcriptome analysis of flower colour reveals the correlation between SNP and differential expression genes in Phalaenopsis - Yu Ding; Ma-Yin Wang; Ding-Hai Yang; Dai-Cheng Hao; Wei-Shi Li; Peng Ling; Shang-Qian Xie (Genes & Genomics, 2023)

Review of Solar Energetic Particle Prediction Models - Kathryn Whitman; Ricky Egeland; Ian G. Richardson; Clayton Allison; Philip Quinn; Janet Barzilla; Irina Kitiashvili; Viacheslav Sadykov; Hazel M. Bain; Mark Dierckxsens; M. Leila Mays; Tilaye Tadesse; et al. (Advances in Space Research, 2023)

SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice - Jia-Wen Chen; Tian-Kai Shan; Tian-Wen Wei; Qi-Qi Jiang; Chong Du; Ling-Feng Gu; Tong-Tong Yang; Liu-Hua Zhou; Si-Bo Wang; Yu-Lin Bao; Hao Wang; Yong Ji; et al. (Archives of Toxicology, 2023)

Subchronic exposure to di-(2-ethylhexyl) phthalate (DEHP) elicits blood–brain barrier dysfunction and neuroinflammation in male C57BL/6J mice - Wen-qiang Ren; Nuo Liu; Yan Shen; Xian-yan Wang; Qiong Zhou; Chen Rui; Xiao-han Yang; Sheng-long Cao; Ling-yu Li; Yán Wāng; Qu-nan Wang (Toxicology, 2023)

Landscape genomics analysis provides insights into future climate change-driven risk in rhesus macaque - Ruifeng Wu; Jiwei Qi; Wenbo Li; Ling Wang; Ying Shen; Jiawen Liu; Yang Teng; Christian Roos; Ming Li (Science of The Total Environment, 2023)

Environmental cadmium exposure facilitates mammary tumorigenesis via reprogramming gut microbiota-mediated glutamine metabolism in MMTV-Erbb2 mice - Yang Yue; Huadong Zhang; Ping Deng; Miduo Tan; Chengzhi Chen; Bo Tang; Jingdian Li; Fengqiong Chen; Qi Zhao; Ling Li; Rongrong Hao; Hui Wang; et al. (Science of The Total Environment, 2023)

Prevalence of paratuberculosis in cattle in China: A systematic review and meta-analysis - Na Lu; Ya-Ling Niu; Yang Song; Dan-Dan Zhang; Jing Jiang; Jiaqi Wei; Hong-Li Geng; Hongwei Cao (Preventive Veterinary Medicine, 2023)

Pijx confers broad-spectrum seedling and panicle blast resistance by promoting the degradation of ATP β subunit and OsRbohC-mediated ROS burst in rice - Ning Xiao; Yunyu Wu; Xiaoxiang Zhang; Zeyun Hao; Zichun Chen; Zefeng Yang; Yue Cai; Ruyi Wang; Ling Yu; Zhiping Wang; Yue Lu; Wei Shi; et al. (Molecular Plant, 2023)

Development of a duplex PCR for the simultaneous detection of EHP and IHHNV and analysis of the correlation between these two pathogens - Yang Gao; Cai-Yi Chen; Zheng Cao; Ru-Qing Yuan; Lin-Rui Chang; Ting Li; Ling-Jun Si; Dong-Chun Yan; Fan Li (Journal of Invertebrate Pathology, 2023)

Evolution and driving forces of water use structures in China - Minhua Ling; Yuanqing Yang; Shuang Li; Cuimei Lv (Journal of Cleaner Production, 2023)

The fate of microplastic pollution in the Changjiang River estuary: A review - Yifei Li; Qingbing Lu; Jian Yang; Yi Xing; Wei Ling; Kai Liu; Qizhen Yang; Hongjie Ma; Zengxin Pei; Tianqi Wu; Haochen Guo; Ziyuan Gao; et al. (Journal of Cleaner Production, 2023)

Cost-benefits analysis of ultra-low emissions standard on air quality and health impact in thermal power plants in China - Ruxing Wan; Ling Tang; Jing Guo; Wenhui Zhai; Ling Li; Yang Xie; Xin Bo; Jun Wu (Journal of Environmental Management, 2023)

Constructing electrochemical sensor using molecular-imprinted polysaccharide for rapid identification and determination of l-tryptophan in diet - Yan-Jun Li; Li-Li Yang; Li Ni; Jia-Min Xiong; Jia-Yuan He; Lian-Di Zhou; Ling Luo; Qi-Hui Zhang; Chun-Su Yuan (Food Chemistry, 2023)

Adamantoyl chloride inhibited replication of the largemouth bass virus via enhanced immunity and inhibition of apoptosis - Mengmeng Wang; Bin Yang; Tao Liu; Pengfei Li; Shangjie Bai; Zhengyang Zhou; Xiang Liu; Maosheng He; Fei Ling; Gaoxue Wang (Fish & Shellfish Immunology, 2023)

Novel slow-release carbon source improves anodic denitrification and electricity generation efficiency in microbial fuel cells - Congyu Li; Yanjie Zhang; Yu Ling; Haiyan Wang; Huan Wang; Guokai Yan; Liang Duan; Weiyang Dong; Yang Chang (Environmental Research, 2023)

Seasonal distribution characteristics and ecological risk assessment of phthalate esters in surface sediment of Songhua River basin - Huan Wang; Congyu Li; Guokai Yan; Yanjie Zhang; Haiyan Wang; Weiyang Dong; Zhaosheng Chu; Yang Chang; Yu Ling (Environmental Pollution, 2023)

Early clues and molecular mechanism involved in neurodegenerative diseases induced in immature mice by combined exposure to polypropylene microplastics and DEHP - Ge Yang; Cunyi Gong; Xinyue Zheng; Fei Hu; Jie Liu; Tian Wang; Xinyue Chen; Min Li; Zhihong Zhu; Ling Zhang; Rui Li (Environmental Pollution, 2023)

Synergistic signal amplification of a 3D Dual-Core DNA nanomachine and PCNs@AuPdCe hybrid nanozymes for ultrasensitive electrochemical detection of Cell-free DNA - Yafei Fu; Jie Li; Dechao Niu; Gangyi Yang; Mengliu Yang; Huawei Shen; Ling Li (Chemical Engineering Journal, 2023)

Dampness and mould in Chinese homes and sick building syndrome (SBS) symptoms – Associations with climate, family size, cleaning and ventilation - Bin Zhang; Dan Norbäck; Hong Cheng; Baizhan Li; Yinping Zhang; Zhuohui Zhao; Qihong Deng; Chen Huang; Xu Yang; Chan Lu; Hua Qian; Tingting Wang; et al. (Building and Environment, 2023)

Transcriptome profiling reveals ethylene formation in rice seeds by trichloroisocyanuric acid - Yang Ling; Zhang Jinshi; Qian Yilu; Lian Jinjin; Li Mei; Zhang Weilin (Plant Cell Reports, 2023)

Enzymatic DNA repairing amplification-powered construction of an Au nanoparticle-based nanosensor for single-molecule monitoring of cytosine deaminase activity in cancer cells - Wen-jing Liu; Rui Song; Xiao-ran Zou; Dong-ling Li; Qinfeng Xu; Chun-yang Zhang (Analytica Chimica Acta, 2023)

Effects of regional groundwater discharge on transverse hyporheic exchange in compound channels - Nairu Wang; Yang Xiao; Lei Huang; Huai Chen; Qian Du; Taotao Zhang; Guangqiu Jin; Ling Li (Advances in Water Resources, 2023)

Functional-structural decoupling in visual network is associated with cognitive decline in patients with type 2 diabetes mellitus: evidence from a multimodal MRI analysis - Min-Hua Ni; Ying Yu; Yang Yang; Ze-Yang Li; Teng Ma; Hao Xie; Si-Ning Li; Pan Dai; Xin-Yu Cao; Yan-Yan Cui; Jun-Ling Zhu; Guang-Bin Cui; et al. (Brain Imaging and Behavior, 2023)

Coupling the digital twin technology and life cycle assessment: Carbon dioxide emissions from polysilicon production - Shengqiang Yang; Zhiqiang Yu; Wenhui Ma; Lin Ma; Chaochun Li; Ling Fu; Ming Li; Zewen Zhao; Yuchen Yang (Sustainable Production and Consumption, 2023)

Effect of salt vertical distribution on sulfate-affected soils deformation - Fan Wang; Shu-Quan Peng; Zai Chen; Ling Fan; Yang Li (Science of The Total Environment, 2023)

Mechanical properties and soil failure process of interface between grouser of tracked mining vehicle and deep-sea sediment - Ling Wang; Xuguang Chen; Lizhen Wang; Zhigang Li; Wendong Yang (Ocean Engineering, 2023)

Innovative pyrite-based constructed wetland-microbial fuel cell for enhancing nutrients removal and bioelectricity generation - Zhi-Wei Zhu; Pei Xu; Li Yu; Xian-Huai Huang; Hou-Yun Yang; Wei-Hua Li; Ping Zhang; Jian Chen; Ling-Tao Kong (Journal of Water Process Engineering, 2023)

Electrolysis characterization of saline wastewater discharged from a subsurface pipe in saline-alkali land - Changkun Yang; Hongguang Liu; Ping Gong; Pengfei Li; Ling Li (Journal of Water Process Engineering, 2023)

An efficiency-driven approach for global ecological industrial parks - Shih-Fang Lo; Wen-Min Lu; Che-Wei Chang; Shiu-Wan Hung; Li-Ling Yang (Journal of Cleaner Production, 2023)

Multiple path-dominated activation of peroxymonosulfate by MOF-derived Fe2O3/Mn3O4 for catalytic degradation of tetracycline - Chensi Tang; Min Cheng; Cui Lai; Ling Li; Zhen Wei; Dengsheng Ma; Li Du; Guangfu Wang; Lu Yang; Lin Tang (Journal of Environmental Chemical Engineering, 2023)

Contribution of carbonaceous strata to intrusion–related Au mineralization: Evidence from trace elements and S–Pb isotopes in pyrite from the Qukulekedong Au–Sb deposit, East Kunlun, NW China - Ling Xing; Wenchang Li; Fucheng Yang; Xiaobo Zhao; David T.A. Symons; Reimar Seltmann; Bing Liu (Gondwana Research, 2023)

Transcriptomic analysis reveals novel desiccation tolerance mechanism of Cronobacter based on type VI secretion system inhibition - Yang Wang; Na Ling; Rui Jiao; Xiyan Zhang; Yuwei Ren; Hui Li; Wenhua Zhao; Qingping Wu; Yingwang Ye (Food Research International, 2023)

Dietary threonine improves muscle nutritional value and muscle hardness associated with collagen synthesis in grass carp (Ctenopharyngodon idella) - Mei-Lan Wen; Pei Wu; Wei-Dan Jiang; Yang Liu; Cai-Mei Wu; Cheng-Bo Zhong; Shu-Wei Li; Ling Tang; Lin Feng; Xiao-Qiu Zhou (Food Chemistry, 2023)

Probiotic components of Bacillus siamensis LF4 mitigated β-conglycinin caused cell injury via modulating TLR2/MAPKs/NF-κB signaling in Lateolabrax maculatus - Zi-Yan Liu; Hong-Ling Yang; Sha Li; Guo-He Cai; Ji-Dan Ye; Chun-Xiao Zhang; Yun-Zhang Sun (Fish & Shellfish Immunology, 2023)

Photoassisted synthesis of high-crystallinity TS-1 with triblock copolymer F127 and its application for photodegradation of erythromycin - Fanjun Meng; Yujie Ling; Yanan Li; Mingrui Guo; Kunze Wei; Mingfei Zhang; Chong Yang; Xifeng Shi; Bo Tang (Chemical Engineering Journal, 2023)

Defective Au nanoparticles manipulated by Au-MgxAl-LDH interplay for alkali-free oxidation of benzyl alcohol - Jingjie Luo; Sihan Yang; Yu Ling; Wenhao Yang; Hongyu Niu; Wenlong Li; Huibin Liu; Changhai Liang (Chemical Engineering Journal, 2023)

Stable cerium isotope analysis of geological materials by MC-ICP-MS - Fang Liu; Mingxing Ling; Zhaofeng Zhang; Wenning Lu; Jianbing Xu; Xin Li; Di Yang; Jiaojiao Wu; Hong Yang (Chemical Geology, 2023)

Exploration of glycosyltransferases mutation status in cervical cancer reveals PARP14 as a potential prognostic marker - Hui Wang; Shen Luo; Xin Wu; Yuanyuan Ruan; Ling Qiu; Hao Feng; Shurong Zhu; Yanan You; Ming Li; Wenting Yang; Yanding Zhao; Xiang Tao; et al. (Glycoconjugate Journal, 2023)
This study investigates the potential role of Glycosyltransferases (GTs) in the glycosylation process and their association with malignant tumors. Specifically, the study focuses on PARP14, a member of GTs, and its potential as a target for tumors in the diagnosis and treatment of cervical cancer. To gather data, the study used somatic mutation data, gene expression data and clinical information from TCGA-CESE dataset as well as tissue samples from cervical cancer patients. Further verification was conducted through RT-qPCR and immunohistochemistry staining on cervical cancer tissues to confirm the expression of PARP14. The study utilized Kaplan-Meier for survival analysis of cervical cancer patient and found significant mutational abnormalities in GTs. The high frequency mutated gene was identified as PARP14. RT-qPCR revealed significantly higher mRNA expression of PARP14 compared to precancerous tissue. Using IHC combined with Kaplan-Meier,patients in the PARP14 high expression group had a better prognosis than the low expression group. The study identified PARP14 as a frequently mutated gene in cervical cancer and proposed its potential role in diagnosis and treatment.

Experimental study on unloading failure characteristics and damage evolution rules of deep diorite based on triaxial acoustic emission tests - Yang Li; Jianxin Fu; Nai Hao; Weidong Song; Ling Yu (Geosciences Journal, 2023)

Adenine phosphate-Cu nanozyme with multienzyme mimicking activity for efficient degrading phenolic compounds and detection of hydrogen peroxide, epinephrine and glutathione - Tong-Qing Chai; Guo-Ying Chen; Ling-Xiao Chen; Jia-Li Wang; Chun-Yan Zhang; Feng-Qing Yang (Analytica Chimica Acta, 2023)

Correction: Angiotensin-(1–9) prevents Angiotensin II-induced endothelial apoptosis through CNPY2/PERK pathway - Chun-ling Guo; Hui-min Liu; Bao Li; Zhao-yang Lu (Apoptosis, 2023)

Alsobacter ponti sp. nov., a novel denitrification and sulfate reduction bacterium isolated from Pearl River sediment - Qi-Qi Deng; Xiao-Qing Luo; Shan-Hui Li; Jia-Ling Li; Pan-Deng Wang; Yang Yuan; Zi-Wen Yang; Wen-Jun Li (Antonie van Leeuwenhoek, 2023)

Contactin-associated protein-like 2 antibody-associated autoimmune encephalitis in children: case reports and systematic review of literature - Yong-kang Cheng; Yao-zheng Ling; Chun-feng Yang; Yu-mei Li (Acta Neurologica Belgica, 2023)

Air pollution exposure and plasma fatty acid profile in pregnant women: a cohort study - Chenhui Yang; Ye Shen; Yiqiong Zhang; Han Xiao; Xiaojie Sun; Jiaqiang Liao; Xinmei Chen; Wenxin Zhang; Ling Yu; Wei Xia; Shunqing Xu; Yuanyuan Li (Environmental Science and Pollution Research, 2023)

Effect of Astragalus membranaceus on Transcriptome and Survival of Hybrid Yellow Catfish (Pseudobagrus vachellii ♂ × Tachysurus fulvidraco ♀) in Response to Aeromonas hydrophila Challenge - Tingshuang Pan; Min Yang; He Jiang; Tong Li; Guoqing Duan; Jun Ling; Qian Gao (Fishes, 2023)
Intensive culturing of hybrid yellow catfish (Pseudobagrus vachellii ♂ × Tachysurus fulvidraco ♀) has increased their mortality. Astragalus membranaceus has been used as an immune stimulant and antioxidant in fish for several years. A. membranaceus was decocted and mixed with the diet. After feeding for 28 d, the hybrid yellow catfish were challenged with Aeromonas hydrophila. To better understand the function of A. membranaceus in the defense of hybrid yellow catfish against A. hydrophila, we analyzed the spleen transcriptome data and relative percentage survival (RPS). There were 396 differentially expressed genes (DEGs) between the A. membranaceus and control groups at 24 h after A. hydrophila stimulation, including 263 upregulated and 133 downregulated DEGs. A significant enrichment of DEGs was found in the A. membranaceus group when the GO enrichment terms in the spleen were analyzed. The qRTPCRresults for the five upregulated and two downregulated DEGs from the spleen, intestine, and liver were consistent with the transcriptome data. The relative percentage survival of A. membranaceus was 85.71% after the fish were challenged with A. hydrophila.

Facile design of surface electric field driven tourmaline/g-C3N4 layered stacked photocatalysts with enhanced photocatalytic activity for antibiotic removal - Xiangwei Tang; Rongdi Tang; Zhanpeng Zhou; Ling Li; Yaocheng Deng; Daoxin Gong; Lihua Yang; Tianwei Song; Mingxuan He (Chemosphere, 2023)

Antiviral effect of prodigiosin isolated from fish intestinal bacteria against Micropterus salmoides rhabdovirus - Kaige Song; Jing Li; Fei Yang; Zhibin Wu; Weichao Chen; Pengfei Li; Fei Ling; Gaoxue Wang (Aquaculture, 2023)

Study on leaching characteristics and biotoxicity of porous asphalt with biochar fillers - Jiawen Liu; Hui Li; John Harvey; Gordon Airey; Sijie Lin; Stephanie Ling Jie Lee; Yitan Zhou; Bing Yang (Transportation Research Part D: Transport and Environment, 2023)

Tuning the intrinsic catalytic sites of magnetite to concurrently enhance the reduction of H2O2 and O2: Mechanism analysis and application potential evaluation - Ling Li; Min Cheng; Eydhah Almatrafi; Lei Qin; Shiyu Liu; Huan Yi; Lu Yang; Zhexin Chen; Dengsheng Ma; Mingming Zhang; Xuerong Zhou; Fuhang Xu; et al. (Journal of Hazardous Materials, 2023)

A bio-inspired mineral precipitation method to improve the freeze-thaw resistance of cement concrete pavement - Hongduo Zhao; Fan Yang; Xin Qian; Yu Tian; Heng Yang; Mengxiao Li; Yi Fang; Jialai Wang; Jianming Ling (Journal of Cleaner Production, 2023)

Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056] - Xu Chen; Ling Li; Fujia Yang; Jinhong Wu; Shaoyun Wang (Food and Chemical Toxicology, 2023)

Loss of Atg5 in Sertoli cells enhances the susceptibility of cadmium-impaired testicular spermatogenesis in mice - Yong-Wei Xiong; Dai-Xin Li; Zheng-Jia Ling; Lu-Lu Tan; Yu-Feng Zhang; Jin Zhang; Hao Li; Wei Chang; Hua-Long Zhu; Jun Zhang; Lan Gao; De-Xiang Xu; et al. (Food and Chemical Toxicology, 2023)

The relationship between extreme ambient temperature and small for gestational age: A cohort study of 1,436,480 singleton term births in China - Xiang Li; Jing Ma; Yang Cheng; Ling Feng; Shaoshuai Wang; Guanpeng Dong (Environmental Research, 2023)

Individual and joint associations of urinary phthalate metabolites with polycystic ovary and polycystic ovary syndrome: Results from the TREE cohort - Min Zhang; Chong Liu; Xiao-Qiong Yuan; Fei-Peng Cui; Yu Miao; Wen Yao; Dan-Yu Qin; Yan-Ling Deng; Pan-Pan Chen; Jia-Yue Zeng; Xiao-Ying Liu; Yang Wu; et al. (Environmental Toxicology and Pharmacology, 2023)

Microwave absorption-based magnetic liquid metal nano-missiles for thermodynamic/immunological cascade hepatoma therapy - Zonghao Liu; Xin Tan; Yueru Huang; Weikun Li; Ning Yang; Renqiang Yuan; Qiang Cheng; Ling Liu; Liqin Ge (Chemical Engineering Journal, 2023)

Heterostructure α-Fe2O3(0 0 1)/g-C3N4(0 0 2) adsorbent to remove As2O3 in simulated coal flue gas: Experimental and DFT study - Biao Wu; Jiang Wu; Jiachen Li; Zhanwei Qiao; Peng Shen; Qilin Zhang; Bowen Zhang; Yang Ling (Chemical Engineering Journal, 2023)

In situ deposition of double Fe-based Fenton catalysts on the porous membrane for the development of multi-defense against various foulants toward highly efficient water purification - Yu-Ling Yang; Gang Wang; Ping Zhu; Lei Tang; Zhi-Xiang Zeng; Li-Jing Zhu (Chemical Engineering Journal, 2023)

Nitidine chloride regulates cell function of bladder cancer in vitro through downregulating Lymphocyte antigen 75 - Shi-shuo Wang; Gao-qiang Zhai; Zhi-guang Huang; Jia-yuan Luo; Juan He; Jie-zhuang Huang; Ling Yang; Chu-nan Xiao; Su-li Li; Kai-rong Chen; Yan-yu Chen; Han-chu Ji; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2023)

A nosocomial Pseudomonas aeruginosa ST3495 isolated from a wild Burmese python (Python bivittatus) with suppurative pneumonia and bacteremia in Hainan, China - Roushan Li; Bo Ling; Jifeng Zeng; Xin Wang; Nuo Yang; Lixia Fan; Guiying Guo; Xuesong Li; Fei Yan; Jiping Zheng (Brazilian Journal of Microbiology, 2023)

Prediction of landslide block movement based on Kalman filtering data assimilation method - Yong Liu; Qing-jie Xu; Xing-rui Li; Ling-feng Yang; Hong Xu (Journal of Mountain Science, 2023)

Accumulation behavior of heavy metals by Bidens pilosa L. from metallurgical slag: effects on plant physiology and absorption characteristics - Meng Wei; Zheng Sun; Bu-li Cui; Yang He; Zhi-cheng Dong; Ling-xiao Meng (Journal of Mountain Science, 2023)

In vivo antibacterial activity of medicinal plant Sophora flavescens against Streptococcus agalactiae infection - Fa‐Li Zhang; Liu Yang; Wei‐Hao He; Ling‐Jun Xie; Fei Yang; Ying‐Hui Wang; Ai‐Guo Huang (Journal of Fish Diseases, 2023)
Streptococcosis disease caused by Streptococcus agalactiae (Group B Streptococcus, GBS) results in a huge economic loss of tilapia culture. It is urgent to find new antimicrobial agents against streptococcosis. In this study, 20 medicinal plants were evaluated in vitro and in vivo to obtain medicinal plants and potential bioactive compounds against GBS infection. The results showed that the ethanol extracts of 20 medicinal plants had low or no antibacterial properties in vitro, with a minimal inhibitory concentration ≥256 mg/L. Interestingly, in vivo tests showed that 7 medicinal plants could significantly inhibit GBS infection in tilapia, and Sophora flavescens (SF) had the strongest anti‐GBS activity in tilapia, reaching 92.68%. SF could significantly reduce the bacterial loads of GBS in different tissues (liver, spleen and brain) of tilapia after treated with different tested concentrations (12.5, 25.0, 50.0 and 100.0 mg/kg) for 24 h. Moreover, 50 mg/kg SF could significantly improve the survival rate of GBS‐infected tilapia by inhibiting GBS replication. Furthermore, the expression of antioxidant gene cat , immune‐related gene c‐type lysozyme and anti‐inflammatory cytokine il‐10 in liver tissue of GBS‐infected tilapia significantly increased after treated with SF for 24 h. Meanwhile, SF significantly reduced the expression of immune‐related gene myd88 and pro‐inflammatory cytokines il‐8 and il‐1β in liver tissue of GBS‐infected tilapia. The negative and positive models of UPLC‐QE‐MS, respectively, identified 27 and 57 components of SF. The major components of SF extract in the negative model were α, α‐trehalose, DL‐malic acid, D‐ (−)‐fructose and xanthohumol, while in the positive model were oxymatrine, formononetin, (−)‐maackiain and xanthohumol. Interestingly, oxymatrine and xanthohumol could significantly inhibit GBS infection in tilapia. Taken together, these results suggest that SF can inhibit GBS infection in tilapia, and it has potential for the development of anti‐GBS agents.

A novel city-level carbon emission quota allocation method for carbon peak and neutrality targets - Ling Tang; Junai Yang; Zixuan Li; Shuying Zhu; Xiaomeng Zhang; Bofeng Cai (Environment, Development and Sustainability, 2023)

A BlendMask-VoVNetV2 method for quantifying fish school feeding behavior in industrial aquaculture - Ling Yang; Yingyi Chen; Tao Shen; Huihui Yu; Daoliang Li (Computers and Electronics in Agriculture, 2023)

Moringa oleifera Lam. leaves as new raw food material: A review of its nutritional composition, functional properties, and comprehensive application - Min Yang; Liang Tao; Xin-Rui Kang; Zi-Lin Wang; Ling-Yan Su; Ling-Fei Li; Fan Gu; Cun-Chao Zhao; Jun Sheng; Yang Tian (Trends in Food Science & Technology, 2023)

Exploring the role of detoxification genes in the resistance of Bursaphelenchus xylophilus to different exogenous nematicidal substances using transcriptomic analyses - Jingxin Cao; Xin Hao; Yang Li; Ruina Tan; Zhixin Cui; Lu Li; Yue Zhang; Jingyu Cao; Mengru Min; Liwei Liang; Zhe Xu; Wei Ma; et al. (Pesticide Biochemistry and Physiology, 2023)

Genomic analysis of Marinomonas algicola SM1966T reveals its role in marine sulfur cycling - Min Zhang; Xiao-Di Wang; Yue Lin; Shu-Yan Wang; Shan Zhang; Jin Cheng; Mei-Ling Sun; Peng Wang; Hui-Hui Fu; Chun-Yang Li; Nan Zhang (Marine Genomics, 2023)

Effects of antibiotics on corncob supported solid-phase denitrification: Denitrification and antibiotics removal performance, mechanism, and antibiotic resistance genes - Yanjie Zhang; Weiyang Dong; Congyu Li; Haiyan Wang; Huan Wang; Yu Ling; Guokai Yan; Yang Chang (Journal of Environmental Sciences, 2023)

A functional intact SUMOylation machinery in Aspergillus flavus contributes to fungal and aflatoxin contamination of food - Xin-Yi Nie; Yang Xue; Ling Li; Zhixin Jiang; Bei Qin; Yu Wang; Shihua Wang (International Journal of Food Microbiology, 2023)

Increased risk of respiratory and allergic diseases in preschoolers from building envelope dampness exposure: Repeated cross-sectional surveys in multicity China - Wei Yu; Yan Zhang; Baizhan Li; Yinping Zhang; Chenqiu Du; Zhuohui Zhao; Dan Norback; Jiao Cai; Qihong Deng; Chan Lu; Hua Qian; Xiaohong Zheng; et al. (Building and Environment, 2023)

Wnt/β-Catenin Promotes the Osteoblastic Potential of BMP9 Through Down-Regulating Cyp26b1 in Mesenchymal Stem Cells - Xin-Tong Yao; Pei-pei Li; Jiang Liu; Yuan-Yuan Yang; Zhen-Ling Luo; Hai-Tao Jiang; Wen-Ge He; Hong-Hong Luo; Yi-Xuan Deng; Bai-Cheng He (Tissue Engineering and Regenerative Medicine, 2023)

Preparation of Continuous Silicate Fiber: Comparison of Natural Basalt and Artificial Stimulant with the Same Chemical Composition - Changjiang Liu; Hankun Zhang; Ling Guo; Zhao Yuan; Ding Wang; Hongchao Li; Letao Jiang; Chuncheng Yang (Natural Resources Research, 2023)

Migraine, chronic kidney disease and kidney function: observational and genetic analyses - Wenqiang Zhang; Li Zhang; Luo Yang; Chenghan Xiao; Xueyao Wu; Peijing Yan; Huijie Cui; Chao Yang; Jingwei Zhu; Xuan Wu; Mingshuang Tang; Yutong Wang; et al. (Human Genetics, 2023)
Epidemiological studies demonstrate an association between migraine and chronic kidney disease (CKD), while the genetic basis underlying the phenotypic association has not been investigated. We aimed to help avoid unnecessary interventions in individuals with migraine through the investigation of phenotypic and genetic relationships underlying migraine, CKD, and kidney function. We first evaluated phenotypic associations using observational data from UK Biobank ( N = 255,896). We then investigated genetic relationships leveraging genomic data in European ancestry for migraine ( N case / N control = 48,975/540,381), CKD ( N case / N control = 41,395/439,303), and two traits of kidney function (estimated glomerular filtration rate [eGFR, N = 567,460] and urinary albumin-to-creatinine ratio [UACR, N = 547,361]). Observational analyses suggested no significant association of migraine with the risk of CKD (HR = 1.13, 95% CI = 0.85–1.50). While we did not find any global genetic correlation in general, we identified four specific genomic regions showing significant for migraine with eGFR. Cross-trait meta-analysis identified one candidate causal variant (rs1047891) underlying migraine, CKD, and kidney function. Transcriptome-wide association study detected 28 shared expression–trait associations between migraine and kidney function. Mendelian randomization analysis suggested no causal effect of migraine on CKD (OR = 1.03, 95% CI = 0.98–1.09; P = 0.28). Despite a putative causal effect of migraine on an increased level of UACR (log-scale-beta = 0.02, 95% CI = 0.01–0.04; P = 1.92 × 10 −3 ), it attenuated to null when accounting for both correlated and uncorrelated pleiotropy. Our work does not find evidence supporting a causal association between migraine and CKD. However, our study highlights significant biological pleiotropy between migraine and kidney function. The value of a migraine prophylactic treatment for reducing future CKD in people with migraine is likely limited.

Mixed farming of rice and millets became the primary subsistence strategy 6400 years ago in the western Huanghuai Plain of Central China: New macrofossil evidence from Shigu - Yuzhang Yang; Miaomiao Yang; Binggui Sun; Weiya Li; Zhijie Cheng; Ling Yao; Wanli Lan; Xin Zhou; Juzhong Zhang (Archaeological and Anthropological Sciences, 2023)

Effect of humic acid-modified attapulgite on polycyclic aromatic hydrocarbon adsorption and release from paddy soil into the overlying water in a rice-crab coculture paddy ecosystem and the underlying process - Nan Sun; Jin Liu; Bo-Wei Qi; Li-Li Lu; Hui-Ling Du; Shuang Li; Chang-Qing Li; Si-Wen Jiang; Zi-Jian Wang; An-Pei Yang; Guang-Lei Zhu; Tian-Yi Wang; et al. (Chemosphere, 2023)

Emission characteristics of benzene series in FCC flue gas - Bohan Wang; Sen Li; DongXu Sun; Jiawei Bian; Hai Zhao; Hong Li; Yang Zhang; Feng Ju; Hao Ling (Chemosphere, 2023)

Benfotiamine attenuates the high-carbohydrate diet-induced mitochondrial redox imbalance in fish Megalobrama amblycephala by activating SIRT3 - Ling Zhang; Ya-Ping Ge; Yang-Yang Huang; Wei-Liang Chen; Wen-Bin Liu; Ding-Dong Zhang; Xiang-Fei Li (Aquaculture, 2023)

Discovery of a substance that enhances the immune response in Litopenaeus vannamei against WSSV: Baicalein, a major component of Scutellaria baicalensis - Li-Peng Shan; Ling Hu; Xu Zhang; Da-Wei Song; Yang Hu; Lei Liu; Jiong Chen (Aquaculture, 2023)

A peptide scanned from the capsid protein of NNV induces effective immune response and protects pearl gentian groupers from viral nervous necrosis - Gao-Yang Liu; Zhong-Yu Zhang; Fei Ling; Peng-Fei Li; Er-Long Wang; Gao-Xue Wang (Aquaculture, 2023)

Sinomenine ameliorates rheumatoid arthritis by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation - Zheng-Meng Jiang; Su-Ling Zeng; Tian-Qing Huang; Yang Lin; Fang-Fang Wang; Xing-Jiao Gao; Jing Li; Ping Li; E-Hu Liu (Science Bulletin, 2023)

Optimization and kinetic analysis of direct acid leaching of vanadium from converter vanadium slag under atmospheric pressure - Yuting Xiong; Ling Wang; Long Wang; Shen Li; Guohua Yang; Chong Cao; Shuxian Liu; Yimiao Nie; Lanbo Jia (Minerals Engineering, 2023)

Nitrogen removal enhanced by its migration and transformation in a three-chamber microbial electrolysis cell - Xiao-Li Yang; Ling Zang; Jia-Jin Chen; Han Xu; Yi-Jing Yang; Hai-Liang Song (Journal of Water Process Engineering, 2023)

Weibull distribution models for describing soil hydraulic properties over the entire matric suction range - Zhenlei Yang; Zi Li; Xin Tong; Shengjie Hu; Jun Wang; Shuting Ji; Ling Li (Journal of Hydrology, 2023)

Study of infectious hypodermal and hematopoietic necrosis virus (IHHNV) infection in different organs of Penaeus vannamei - Zi-Hao Hou; Yang Gao; Jing-Jing Wang; Cai-Yi Chen; Lin-Rui Chang; Ting Li; Ling-Jun Si; Fan Li; Dong-Chun Yan (Journal of Invertebrate Pathology, 2023)

Chronic exposure to (2 R,6 R)-hydroxynorketamine induces developmental neurotoxicity in hESC-derived cerebral organoids - Zhulin Du; Zhenle Zang; Jing Luo; Tianyao Liu; Ling Yang; Yun Cai; Liuyongwei Wang; Dandan Zhang; Jinghui Zhao; Junwei Gao; Keyi Lv; Lian Wang; et al. (Journal of Hazardous Materials, 2023)

Application of the global stability index method to shelf-life prediction and physiochemical characteristics analysis of enteral feeding formula during storage - Hong Yang; Li Li Xu; Ling Hou; Tong Cheng Xu; Shu Hong Ye (Journal of Food Engineering, 2023)

Corrigendum to “Co-folding of soy protein isolates and shellac by structural interplays to induce hydrogels” [Food Hydrocolloids 139 (2023) 108527] - Yang Guo; Zhi-guo Zhang; Jing Cai; Wei-rong Li; Ling-yun Chen; Wei-cheng Wu (Food Hydrocolloids, 2023)

Combined effects of light pollution and vegetation height on behavior and body weight in a nocturnal rodent - Ling-Ying Shuai; Li-Qing Wang; Yang Xia; Jin-Yu Xia; Kang Hong; Ya-Nan Wu; Xin-Yi Tian; Fu-Shun Zhang (Environmental Pollution, 2023)

High-entropy alloy nanoparticles/biochar as an efficient catalyst for high-performance treatment of organic pollutants - Ling-Zhen Miao; Yu-Xin Guo; Zi-Yi Liu; Yang Li; Jie Zhu; Lei Wu (Chemical Engineering Journal, 2023)

Electrochemical hydrogenation detoxication of p-nitrophenol via self-supported rGO/CoP/CF electrode: Performance, mechanism and biotoxicity - Chang Tan; Fubing Yao; Chi Ma; Li He; Xu Yang; Tantan Wang; Ling Xiang; Guanlong Yu; Zhigang Yu; Zhuotong Zeng; Chang Zhang (Chemical Engineering Journal, 2023)

Anaerobic-aerobic treatment of high-strength and recalcitrant textile dyeing effluents - Hai-Yong Yao; Hui Guo; Feng Shen; Ting Li; De-Yang Show; Ming Ling; Yue-Gen Yan; Kuan-Yeow Show; Duu-Jong Lee (Bioresource Technology, 2023)

Prediction of Omeprazole Pharmacokinetics and its Inhibition on Gastric Acid Secretion in Humans Using Physiologically Based Pharmacokinetic-Pharmacodynamic Model Characterizing CYP2C19 Polymorphisms - Shuai Li; Lei Xie; Lu Yang; Ling Jiang; Yiting Yang; Hao Zhi; Xiaodong Liu; Hanyu Yang; Li Liu (Pharmaceutical Research, 2023)

Chitinolyticbacter albus sp. Nov., A Novel Chitin-Degrading Bacterium Isolated from Ancient Wood Rhizosphere Soil - Meng-Yu Zhang; Jiang-Yuan Zhao; Le-Le Li; Cheng Ling; Jing Tang; Song-Guo Liang; Jian-Yu Li; Xiao-Di Liu; Lu-Yao Feng; Pei-Wen Yang; Zhu-Feng Shi; Zhang-Gui Ding; et al. (Current Microbiology, 2023)

Experimental study on seismic performance of novel precast concrete beam-column joints using mechanical connections - Chuanzhi Sun; Mei-Ling Zhuang; Liutao Bai; Li Gao; Changrong Yu; Jun Yang; Hanbo Zhu; Yan Qiao; Yuefeng Shao; Weihua Zhang (Bulletin of Earthquake Engineering, 2023)

Peak extraction and classification from digital elevation models based on the relationship between morphological characteristics and spatial position - Ming-wei Zhao; Yue Fang; Can-can Yang; Xiao-xiao Ju; Xiao-li Huang; Ling Jiang; Chun Wang; Yan Xu (Journal of Mountain Science, 2023)

Stable isotope labeling differential glycans discovery in the serum of acute myocardial infarction by ultrahigh-performance liquid chromatography-quadrupole-Orbitrap high resolution mass spectrometry - Xi-Ling Li; Yuxuan Li; Shuyun Xiao; Qingsong Li; Chengqiang Han; Danyang Liu; Tengfei Cui; Xiyang Rao; Kenichiro Todoroki; Guang Yang; Jun Zhe Min (Analytica Chimica Acta, 2023)

Validity, applicability, and universality of fractal scaling laws for lakes in China - Shengjie Hu; Zhenlei Yang; Sergio A. G. Torres; Zipeng Wang; Ling Li (Aquatic Sciences, 2023)

Using modular connectome-based predictive modeling to reveal brain-behavior relationships of individual differences in working memory - Huayi Yang; Junjun Zhang; Zhenlan Jin; Pouya Bashivan; Ling Li (Brain Structure and Function, 2023)

Dietary zearalenone alters gill epithelial morphology and subsequent risk of infection: Insights from a freshwater grass carp (Ctenopharyngodon idella) model - Hong-Yun Zhang; Ya-Li Wang; Wei-Dan Jiang; Pei Wu; Yang Liu; Lu Zhang; Hai-Feng Mi; Sheng-Yao Kuang; Ling Tang; Shu-wei Li; Xiao-Qiu Zhou; Lin Feng (Aquaculture, 2023)

Aflatoxin B1 exposure induced developmental toxicity and inhibited muscle development in zebrafish embryos and larvae - Xiang-Ning He; Pei Wu; Wei-Dan Jiang; Yang Liu; Sheng-Yao Kuang; Ling Tang; Hong-Mei Ren; Hua Li; Lin Feng; Xiao-Qiu Zhou (Science of The Total Environment, 2023)

Cytotoxic steroids from the stems of Strophanthus divaricatus - Hong-Ling Ran; Sheng-Zhuo Huang; Hao Wang; Li Yang; Cui-Juan Gai; Rui-Jun Duan; Hao-Fu Dai; Ya-Li Guan; Wen-Li Mei (Phytochemistry, 2023)

Aromatic polyketide aspergillones A-D from the endophytic fungus Aspergillus sclerotiorum - Yue Hu; Yi-Lei Zheng; Zhuo-Da Zhou; Min Li; Ming-Ling Wang; Ling-Yi Kong; Ming-Hua Yang (Phytochemistry Letters, 2023)

Complete genome sequence of Bacillus cereus 2-6A, a marine exopolysaccharide-producing bacterium isolated from deep-sea hydrothermal sediment of the Pacific Ocean - Xuan Zou; Chuan-Lei Suo; Xiao-Mei Geng; Chun-Yang Li; Hui-Hui Fu; Yi Zhang; Peng Wang; Mei-Ling Sun (Marine Genomics, 2023)

Changes in biochemical metabolites in manila clam after a temporary culture with high-quality microalgal feed mixed with the dinoflagellate species Karlodinium veneficum and K. zhouanum - Yuanbo Pan; Ran Meng; Yanrong Li; Ling Yang; Limin Mei; Yanhua Wu; Jilin Xu; Chengxu Zhou; Xiaojun Yan (Harmful Algae, 2023)

Effects of drying methods on bioactive components of Ganoderma lucidum fermented whole wheat in products & in vitro digestive model - Yang Li; Fengying Gu; Xin Guo; Qiaozhen Zhang; Runrun Hu; Ling Qin; Qiang Wang; Feng Wang (Food Research International, 2023)

Investigation on the interaction between 1,3-dimethyltrisulfide and aroma-active compounds in sesame-flavor baijiu by Feller Additive Model, Odor Activity Value and Partition Coefficient - Shiqi Yang; Guihu Zhang; Ling Xu; Jiawen Duan; Hehe Li; Jinyuan Sun; Baoguo Sun (Food Chemistry, 2023)

The fiber-bound polyphenols from highland barley with inhibitory effects against carbonyls during in vitro digestion of cookies and French fries - Jinxin Li; Hao Zhang; Xijuan Yang; Ling Zhu; Gangcheng Wu; Hui Zhang (Food Bioscience, 2023)

Commensal Bacillus siamensis LF4 ameliorates β-conglycinin induced inflammation in intestinal epithelial cells of Lateolabrax maculatus - Zi-Yan Liu; Hong-Ling Yang; Xi-Yue Ding; Sha Li; Guo-He Cai; Ji-Dan Ye; Chun-Xiao Zhang; Yun-Zhang Sun (Fish & Shellfish Immunology, 2023)

Optimization and mechanism of phosphorus removal in plant-biofilm oxidation ditches: Plant uptake, iron plaque adsorption, and rhizosphere regulation - Wen Liu; Feng-Juan Yang; Yong-Ling Zhou; Yi-Yong Li; Hui Liu; Dan A (Ecological Engineering, 2023)

Nanocomposite hydrogels flexible sensors with functional cellulose nanocrystals for monitoring human motion and lactate in sweat - Pan Li; Ziyue Ling; Xuanqi Liu; Liangjiu Bai; Wenxiang Wang; Hou Chen; Huawei Yang; Lixia Yang; Donglei Wei (Chemical Engineering Journal, 2023)

A notable reversible thermochromic (3,3-difluoropyrrolidinium)2[CuCl4] with ferroelectricity and ferroelasticity - Shulin Jiao; Zheng Tang; Dong Li; Cuiping Xu; Zhu Yang; Peng Chen; Xiaofan Sun; Hong-Ling Cai; Xiaoshan Wu (Chemical Engineering Journal, 2023)

Superior triethylamine sensing platform based on MOF activated by carbon dots for photoelectric dual-mode in biphasic system - Xue-Chun Yang; Sha-Qi Fu; Qian-Li Li; Zheng Jiao; Jing-Tai Zhao; Yun Guo; Zhi-Jun Zhang; Song Gao; Ling-Li Cheng (Chemical Engineering Journal, 2023)

Effects of Bacillus subtilis BS-Z15 on Intestinal Microbiota Structure and Body Weight Gain in Mice - Jun Yang; Huan-Chen Ning; Qi Zhang; Jun-Qi Yue; Xi-Yuan Cao; Jin-Yu Li; Ling Liu; He-Ping Zhao; Hui-Xin Zhao (Probiotics and Antimicrobial Proteins, 2023)

Impact of different nitrogen additions on microbes and exopolysaccharides excretion in cyanobacterial biocrusts - Long Qian; Jingshang Xiao; Zulin Zhang; Lie Yang; Ling Xia; María E. Farías; Rosa María Torres; Li Wu (Plant and Soil, 2023)

Ndufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2 - Fang Fu; Chen Chen; Kun Du; Lu-shan Li; Ru Li; Ting-ying Lei; Qiong Deng; Dan Wang; Qiu-xia Yu; Xin Yang; Jin Han; Min Pan; et al. (Molecular Neurobiology, 2023)
The Dandy–Walker malformation (DWM) is characterized by neuron dysregulation in embryonic development; however, the regulatory mechanisms associated with it are unclear. This study aimed to investigate the role of NADH dehydrogenase 1 alpha subcomplex 4 (NDUFA4) in regulating downstream signaling cascades and neuronal proliferation and apoptosis. Ndufa4 overexpression promoted the proliferation of neurons and inhibited their apoptosis in vitro, which underwent reverse regulation by the Ndufa4 short hairpin RNAs. Ndufa4 -knockout (KO) mice showed abnormal histological alterations in the brain tissue, in addition to impaired spatial learning capacity and exploratory activity. Ndufa4 depletion altered the microRNA expressional profiles of the cerebellum: Ndufa4 inhibited miR-145a-5p expression both in the cerebellum and neurons. miR-145a-5p inhibited the proliferation of neurons and promoted their apoptosis. Ndufa4 promoted and miR-145a-5p inhibited the expression of human homer protein homolog 1 and cyclin D2 in neurons. Thus, Ndufa4 promotes the proliferation of neurons and inhibits their apoptosis by inhibiting miR-145a-5p, which directly targets and inhibits the untranslated regions of Homer1 and Ccnd2 expression.

Clinical and genome-wide association analysis of chemoradiation-induced hearing loss in nasopharyngeal carcinoma - Yong-Qiao He; Lu-Ting Luo; Tong-Min Wang; Wen-Qiong Xue; Da-Wei Yang; Dan-Hua Li; Hua Diao; Ruo-Wen Xiao; Chang-Mi Deng; Wen-Li Zhang; Ying Liao; Yan-Xia Wu; et al. (Human Genetics, 2023)
Chemoradiation-induced hearing loss (CRIHL) is one of the most devasting side effects for nasopharyngeal carcinoma (NPC) patients, which seriously affects survivors’ long-term quality of life. However, few studies have comprehensively characterized the risk factors for CRIHL. In this study, we found that age at diagnosis, tumor stage, and concurrent cisplatin dose were positively associated with chemoradiation-induced hearing loss. We performed a genome-wide association study (GWAS) in 777 NPC patients and identified rs1050851 (within the exon 2 of NFKBIA ), a variant with a high deleteriousness score, to be significantly associated with hearing loss risk (HR = 5.46, 95% CI 2.93–10.18, P = 9.51 × 10 –08 ). The risk genotype of rs1050851 was associated with higher NFKBIA expression, which was correlated with lower cellular tolerance to cisplatin. According to permutation-based enrichment analysis, the variants mapping to 149 hereditary deafness genes were significantly enriched among GWAS top signals, which indicated the genetic similarity between hereditary deafness and CRIHL. Pathway analysis suggested that synaptic signaling was involved in the development of CRIHL. Additionally, the risk score integrating genetic and clinical factors can predict the risk of hearing loss with a relatively good performance in the test set. Collectively, this study shed new light on the etiology of chemoradiation-induced hearing loss, which facilitates high-risk individuals’ identification for personalized prevention and treatment.

ADGB variants cause asthenozoospermia and male infertility - Ronggui Qu; Zhihua Zhang; Ling Wu; Qun Li; Jian Mu; Lin Zhao; Zheng Yan; Wenjing Wang; Yang Zeng; Ruyi Liu; Jie Dong; Qiaoli Li; et al. (Human Genetics, 2023)

Pseudomonas subflava sp. nov., a new Gram-negative bacterium isolated from Guishan in Yunnan province, south–west China - Cheng Ling; Jiang-Yuan Zhao; Le-Le Li; Zhang-Gui Ding; Meng-Yu Zhang; Jing Tang; Song-Guo Liang; Jian-Yu Li; Xiao-Di Liu; Lu-Yao Feng; Pei-Wen Yang; Yao Lu; et al. (Antonie van Leeuwenhoek, 2023)

Isolation and characterization of three pairs of verrucosidin epimers from the marine sediment-derived fungus Penicillium cyclopium and configuration revision of penicyrone A and related analogues - Yan-He Li; Attila Mándi; Hong-Lei Li; Xiao-Ming Li; Xin Li; Ling-Hong Meng; Sui-Qun Yang; Xiao-Shan Shi; Tibor Kurtán; Bin-Gui Wang (Marine Life Science & Technology, 2023)
Verrucosidins, a methylated α-pyrone class of polyketides rarely reported upon, have been implicated in one or more neurological diseases. Despite the significance of verrucosidins as neurotoxins, the absolute configurations of most of the derivatives have not been accurately characterized yet. In this study, three pairs of C-9 epimeric verrucosidin derivatives, including the known compounds penicyrones A and B ( 1a/1b ) and 9- O -methylpenicyrones A and B ( 2a/2b ), the new compounds 9- O- ethylpenicyrones A and B ( 3a/3b ), together with the related known derivative verrucosidin ( 4 ), were isolated and identified from the culture extract of Penicillium cyclopium SD-413, which was obtained from the marine sediment collected from the East China sea. Their structures were established based on an in-depth analysis of nuclear magnetic resonances (NMR) and mass spectroscopic data. Determination of the absolute configurations of these compounds was accomplished by Mosher’s method and time-dependent density functional theory (TDDFT) calculations of electronic circular dichroism (ECD) and optical rotation (OR). The configurational assignment of penicyrone A demonstrated that the previously reported C-6 absolute configuration of verrucosidin derivatives needs to be revised from (6 S ) to (6 R ). The 9 R /9 S epimers of compounds 1–3 were found to exhibit growth inhibition against some pathogenic bacteria, indicating that they have potential as lead compounds for the creation of antimicrobial agents.

Calcium enhances phosphorus reclamation during biochar formation: Mechanisms and potential application as a phosphorus fertilizer in a paddy soil - Hongyan Nan; Fan Yang; Deping Li; Xinde Cao; Xiaoyun Xu; Hao Qiu; Ling Zhao (Waste Management, 2023)

High spatiotemporal resolution vehicular emission inventory in Beijing-Tianjin-Hebei and its surrounding areas (BTHSA) during 2000–2020, China - Chuanyong Zhu; Xinyue Qu; Mengyi Qiu; Changtong Zhu; Chen Wang; Baolin Wang; Lei Sun; Na Yang; Guihuan Yan; Chongqing Xu; Ling Li (Science of The Total Environment, 2023)

Colonic mechanism of serum NAD+ depletion induced by DEHP during pregnancy - Yun Hong; Xia Ning; Yue-yue Liang; Xiao-lu Li; Ya Cui; Wei Wu; Yang Cai; Shuai Zhao; Meng Zhu; Tian-xiao Zhong; Hua Wang; De-xiang Xu; et al. (Science of The Total Environment, 2023)

Underestimation of biomass burning contribution to PM2.5 due to its chemical degradation based on hourly measurements of organic tracers: A case study in the Yangtze River Delta (YRD) region, China - Qing Li; Kun Zhang; Rui Li; Liumei Yang; Yanan Yi; Zhiqiang Liu; Xiaojuan Zhang; Jialiang Feng; Qiongqiong Wang; Wu Wang; Ling Huang; Yangjun Wang; et al. (Science of The Total Environment, 2023)

Conversion of swine manure into biochar for soil amendment: Efficacy and underlying mechanism of dissipating antibiotic resistance genes - Yan He; Xin Zhao; Siman Zhu; Long Yuan; Xinyi Li; Zhihan Feng; Xuan Yang; Ling Luo; Yinlong Xiao; Yan Liu; Lilin Wang; Ouping Deng (Science of The Total Environment, 2023)

Global, regional, and national burden of preterm birth attributable to ambient and household PM2.5 from 1990 to 2019: Worsening or improving? - Xiao-Xuan Liu; Shu-Jun Fan; Ya-Na Luo; Li-Xin Hu; Cong-Cong Li; Yi-Dan Zhang; Jia-Xin Li; Hui-Ling Qiu; Guang-Hui Dong; Bo-Yi Yang (Science of The Total Environment, 2023)

Reliability and availability evaluation on hydraulic system of ship controllable pitch propeller based on evidence theory and dynamic Bayesian network - Xu Bai; Hao Ling; Xiao-fang Luo; Yu-shan Li; Li Yang; Ji-chuan Kang (Ocean Engineering, 2023)

Deciphering the photoactive species-directed antibacterial mechanism of bismuth oxychloride with modulated nanoscale thickness - Liuzhu Zhou; Xinyi Zhu; Jing Yang; Ling Cai; Li Zhang; Huijun Jiang; Hongjie Ruan; Jin Chen (Journal of Environmental Management, 2023)

Co-folding of soy protein isolates and shellac by structural interplays to induce hydrogels - Yang Guo; Zhi-guo Zhang; Jing Cai; Wei-rong Li; Ling-yun Chen; Wei-cheng Wu (Food Hydrocolloids, 2023)

Nickel exposure induces gut microbiome disorder and serum uric acid elevation - Jinfeng Yang; Pengya Feng; Zhenmin Ling; Aman Khan; Xing Wang; Yanli Chen; Gohar Ali; Yitian Fang; El-Sayed Salama; Ximei Wang; Pu Liu; Xiangkai Li (Environmental Pollution, 2023)

Triple-enzyme-mimicking AuPt3Cu hetero-structural alloy nanozymes towards cascade reactions in chemodynamic therapy - Lin Li; Yuanyuan Hu; Yuhe Shi; Yang Liu; Tianqi Liu; Huiwen Zhou; Wenxin Niu; Ling Zhang; Jiaheng Zhang; Guobao Xu (Chemical Engineering Journal, 2023)

Design of a highly efficient Cu-based catalyst with two functional areas: The role of Cu0 and oxygen vacancies in Fenton-like system - Cui Lai; Lu Yang; Ling Li; Dengsheng Ma; Min Cheng; Shiyu Liu; Mingming Zhang; Huchuan Yan; Chensi Tang; Zhexin Chen; Lin Tang (Chemical Engineering Journal, 2023)

Rab37 Promotes Endothelial Differentiation and Accelerates ADSC-Mediated Diabetic Wound Healing through Regulating Secretion of Hsp90α and TIMP1 - Haili Huang; Ling Liang; Dan Sun; Jin Li; Wentao Wang; Lixia Zha; Jiaqi Yang; Kunyan Pan; Xianmou Fan; Chengzhang He; Xudong Tang; Peihua Zhang (Stem Cell Reviews and Reports, 2023)

Disease resistance conferred by components of essential chrysanthemum oil and the epigenetic regulation of OsTPS1 - Chuansong Zhan; Long Lei; Hao Guo; Shen Zhou; Congping Xu; Zixin Liu; Zichen Wu; Yuan Deng; Yuanyuan Miao; Yu Han; Meng Zhang; Hua Li; et al. (Science China Life Sciences, 2023)

Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy - Xiaomin Chen; Jiahui Liu; Jun Li; Yinpeng Xie; Zichen Yu; Lu Shen; Qingfeng Liu; Wei Wu; Qiang Zhao; Haoxiang Lin; Gaotong Liu; Qiuping Luo; et al. (Genes & Genomics, 2023)

Study on the resourceful reuse in SBS-modified asphalt of waste bagasse fibers based on green modification with tannic acid and FeOOH - Ling Yang; Fuhu Han; Yaseen Muhammad; Yu Liu; Zhenxia Zhao; Hao Kong; Jing Li; Honggang Zhang (Environmental Science and Pollution Research, 2023)

Metagenomic insights into the effects of benzyl dodecyl dimethyl ammonium bromide (BDAB) shock on bacteria-driven nitrogen removal in a moving-bed biofilm reactor (MBBR) - Jing Wang; Ling Li; Baihui Chi; Jiajia Shan; Xianliang Yi; Yang Liu; Hao Zhou (Chemosphere, 2023)

In vitro and in vivo anti-tumor activity of Coenzyme Q0 against TWIST1-overexpressing HNSCC cells: ROS-mediated inhibition of EMT/metastasis and autophagy/apoptosis induction - Hsin-Ling Yang; Li-Wen Chiu; Yi-An Lin; Sudhir Pandey; Chithravel Vadivalagan; Jiunn-Wang Liao; Yugandhar Vudhya Gowrisankar; Hui-Jye Chen; Hui-Yi Lin; You-Cheng Hseu (Toxicology and Applied Pharmacology, 2023)

Effects of low salinity stress on osmoregulation and gill transcriptome in different populations of mud crab Scylla paramamosain - Wen-Bin Xu; Yan-Mei Zhang; Bang-Ze Li; Chen-Yang Lin; Da-Yong Chen; Yuan-Xin Cheng; Xiao-Ling Guo; Wei-Ren Dong; Miao-An Shu (Science of The Total Environment, 2023)

Proteomic analysis reveals differential responsive mechanisms in Solanum nigrum exposed to low and high dose of cadmium - Ling-Yu Song; Xiang Liu; Lu-Dan Zhang; Wen-Jun Hu; Chao-Qun Xu; Jing Li; Shi-Wei Song; Ze-Jun Guo; Chen-Yang Sun; Han-Chen Tang; Ji-Cheng Wang; Xue-Yi Zhu; et al. (Journal of Hazardous Materials, 2023)

Genome-resolved metagenomics reveals depth-related patterns of microbial community structure and functions in a highly stratified, AMD overlaying mine tailings - Zhen-Hao Luo; Qi Li; Nan Chen; Ling-Yun Tang; Bin Liao; Tao-Tao Yang; Li-Nan Huang (Journal of Hazardous Materials, 2023)

Recycling cinder in efficient methane production from wheat straw via solid-state anaerobic digestion (SS-AD) - Hongyi Lyu; Jing Chen; Mengyi Wang; Huaiwen Zhang; Heng Wu; Tairan Liu; Xuanmin Yang; Xiaohui Guo; Xiaojiao Wang; Ping Ai; Zhenyu Li; Minsong Lin; et al. (Chemical Engineering Journal, 2023)

Formation of Fe(IV) over a wide pH range via iron-carbon composite-catalyzed persulfate activation - Hong Li; Rongliang Qiu; Yetao Tang; Xiaoguang Duan; Yanling Gu; Hailan Yang; Qiang Chen; Zihan Shu; Ling Xiang; Shaobo Liu; Xiaofei Tan (Chemical Engineering Journal, 2023)

Prenatal and postnatal decoration in residence are associated with childhood allergies and respiratory diseases: A 10-year repeated retrospective observational study - Lexiang Wang; Wei Yu; Baizhan Li; Yan Zhang; Jiao Cai; Zhuohui Zhao; Dan Norbäck; Qihong Deng; Hua Qian; Xin Zhang; Tingting Wang; Ling Zhang; et al. (Building and Environment, 2023)

Cesium exposure and pulmonary function decline: Potential mediating role of oxidative stress in chronic obstructive pulmonary disease patients - Min-Min Tang; Xue-Feng Hou; Jing Sun; Jia-Yi Cheng; You-Peng Deng; Meng-Die Li; Ling Liu; Dong-Xu Hua; Jin Yang; Ya-Lin Jiang; Lin Fu; Hui Zhao (Atmospheric Pollution Research, 2023)

Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders - Chongyun Wu; Peibin Zou; Shu Feng; Ling Zhu; Fanghui Li; Timon Cheng-Yi Liu; Rui Duan; Luodan Yang (Molecular Neurobiology, 2023)

circANKRD17(has_circ_0007883) confers paclitaxel resistance of ovarian cancer via interacting with FUS to stabilize FOXR2 - Yue-Xiu Liang; Lian-Ling Zhang; Li Yang (Molecular and Cellular Biochemistry, 2023)

Production of MSTN knockout porcine cells using adenine base-editing-mediated exon skipping - Shuai-peng Yang; Xiang-xing Zhu; Zi-xiao Qu; Cai-yue Chen; Yao-bing Wu; Yue Wu; Zi-dan Luo; Xin-yi Wang; Chu-yu He; Jia-wen Fang; Ling-qi Wang; Guang-long Hong; et al. (In Vitro Cellular & Developmental Biology - Animal, 2023)

Changes in the Microbiota and their Roles in Patients with Type 2 Diabetes Mellitus - Qiao-ling He; Hui-chao Wang; Yu-ke Ma; Rui-lin Yang; Zhi-feng Dai; Jing-nan Yang; Yao Xu; Dan-dan Wei; Li-ping Zhu; Xu-hong Lin (Current Microbiology, 2023)

Two Novel Species of Mesophoma gen. nov. from China - Ai-Ling Yang; Lin Chen; Lu Cheng; Jin-Peng Li; Zhao-Ying Zeng; Han-Bo Zhang (Current Microbiology, 2023)

A Tiered Ecological Risk Assessment of Caffeine by Using Species Sensitivity Distribution Method in the Nansi Lake Basin - Lei Zheng; Juan Zhang; Yinan Wu; Linlin Li; Junhong Ling; Sai Wang; Wenlong Yang; Yezhu Yin; Liang Dong; Yizhang Zhang (Bulletin of Environmental Contamination and Toxicology, 2023)

One-pot RPA-Cas12a assay for instant and visual detection of Burkholderia pseudomallei - Ling Deng; Xiaoyi He; Ke Liu; Yuanli Li; Han Xia; Hang Qian; Xiaoxue Lu; Xuhu Mao; Yang Xiang (Analytica Chimica Acta, 2023)

Multiplex single-cell droplet PCR with machine learning for detection of high-risk human papillomaviruses - Yizheng Huang; Linjun Sun; Wenwen Liu; Ling Yang; Zhigang Song; Xin Ning; Weijun Li; Manqing Tan; Yude Yu; Zhao Li (Analytica Chimica Acta, 2023)

Angiotensin-(1–9) prevents angiotensin II-induced endothelial apoptosis through CNPY2/PERK pathway - Chun-ling Guo; Hui-min Liu; Bao Li; Zhao-yang Lu (Apoptosis, 2023)

Potential antiplatelet aggregation metabolites from the discarded sorghum ( Sorghum bicolor L.) root - Wan-ting Xu; Qiao An; Ling-hui Ruan; Fei Zhou; Lang Zhou; Mei Peng; Li-lang Li; Xiao-sheng Yang; Qi-ji Li; Juan Yang (Natural Product Research, 2023)

Research on the utilization of ultra-long carbon nanotubes in lithium-ion batteries based on an environment-friendly society - Xuanyu Yang; Ziling Xie; Xibin Lu; Min Wei; Xinxin Tan; Haihua Ling; Ying Li (Environmental Science and Pollution Research, 2023)

The essentiality of dietary myo-inositol to oriental river prawn (Macrobrachium nipponense): Evidence in growth performance, lipid metabolism and mitochondrial function - Ming-Yang Liu; Miao Sun; Ling Zhang; Ya-Ping Ge; Bo Liu; Xiang-Fei Li (Aquaculture, 2023)

Creation of intermuscular bone-free mutants in amphitriploid gibel carp by editing two duplicated runx2b homeologs - Rui-Hai Gan; Zhi Li; Zhong-Wei Wang; Xi-Yin Li; Yang Wang; Xiao-Juan Zhang; Jin-Feng Tong; Yue Wu; Ling-Yun Xia; Ze-Xia Gao; Li Zhou; Jian-Fang Gui (Aquaculture, 2023)

Experimental investigation on dynamic characteristics of fiber-binder modified subgrade filler after freezing-thawing under cyclic loading - Jiahui Wang; Yan Li; Ping Yang; Xianzhang Ling; Yingying Zhao; Lei Su (Transportation Geotechnics, 2023)

GSK2795039 prevents RIP1-RIP3-MLKL-mediated cardiomyocyte necroptosis in doxorubicin-induced heart failure through inhibition of NADPH oxidase-derived oxidative stress - Xiao-Juan Zhang; Lu Li; Ai-Ling Wang; Hong-Xia Guo; Hui-Ping Zhao; Rui-Fang Chi; Hui-Yu Xu; Li-Guo Yang; Bao Li; Fu-Zhong Qin; Jia-Pu Wang (Toxicology and Applied Pharmacology, 2023)

Di-(2-ethylhexyl) phthalate exposure impairs cortical development in hESC-derived cerebral organoids - Ling Yang; Jiao Zou; Zhenle Zang; Liuyongwei Wang; Zhulin Du; Dandan Zhang; Yun Cai; Minghui Li; Qiyou Li; Junwei Gao; Haiwei Xu; Xiaotang Fan (Science of The Total Environment, 2023)

Perfluorobutanesulfonate exposure induces metabolic disturbances in different regions of mouse gut - Ling Chen; Mengyuan Zhu; Yafeng Liu; Zhongchao Yang; Huan Li; Hongxin Mu; Su Liu; Bing Wu (Science of The Total Environment, 2023)

Improving VOC control strategies in industrial parks based on emission behavior, environmental effects, and health risks: A case study through atmospheric measurement and emission inventory - Ling Li; Dan Zhang; Wei Hu; Yi Yang; Sidi Zhang; Rui Yuan; Pingjiang Lv; Weidong Zhang; Yong Zhang; Yunhuai Zhang (Science of The Total Environment, 2023)

Prediction of BLEVE loads on structures using machine learning and CFD - Qilin Li; Yang Wang; Ling Li; Hong Hao; Ruhua Wang; Jingde Li (Process Safety and Environmental Protection, 2023)

Biological effects on the migration and transformation of microplastics in the marine environment - Songyao Fan; Zezheng Yan; Ling Qiao; Feng Gui; Tiejun Li; Qiao Yang; Xiaoling Zhang; Chengzhe Ren (Marine Environmental Research, 2023)

A 13 million-year record of Li isotope compositions in island carbonates: Constraints on bulk inorganic carbonate as a global seawater Li isotope archive - Guang-Yi Wei; Feifei Zhang; Yi-Sheng Yin; Yi-Bo Lin; Philip A.E. Pogge von Strandmann; Mengchun Cao; Na Li; Guolin Xiong; Xinran Chen; Caiwei Fan; Changgui Xu; Fei Tan; et al. (Geochimica et Cosmochimica Acta, 2023)

Accurate quantification of TAGs to identify adulteration of edible oils by ultra-high performance liquid chromatography-quadrupole-time of flight-tandem mass spectrometry - Hailian Wei; Dandan Yang; Jin Mao; Qi Zhang; Ling Cheng; Xianglong Yang; Peiwu Li (Food Research International, 2023)

Insight into the boosted ZEN degradation over defective Bi2WO6 ultrathin layers: ROS-mediated mechanism and application in corn oil - Xianglong Yang; Ling Cheng; Qi Zhang; Li Yu; Xin Qi; Jin Mao; Peiwu Li (Food Chemistry, 2023)

Behavior of wheat flour dough at different pretreated temperatures through rheological characteristics and molecular interactions of proteins - Yu-ling Yang; Er-qi Guan; Ting-jing Zhang; Fei Xu; Meng-meng Li; Ke Bian (Food Chemistry, 2023)

Diazotized polyamide membranes on commercial polyethylene textile with simultaneously improved water permeance, salt rejections and anti-fouling - Ling Wang; Hong Yang; Hongxiang Li; Peng Lu; Yifei Yu; Xianjuan Zhang; Yi Wang; Jianzhong Xia; Dingbing He; Yanshuo Li (Desalination, 2023)

High-activity and stability graphite felt supported by Fe, N, S co-doped carbon nanofibers derived from bimetal-organic framework for vanadium redox flow battery - Qingchun Jiang; Yujie Ren; Yujie Yang; Honghao Liu; Ling Wang; Jin Li; Lei Dai; Zhangxing He (Chemical Engineering Journal, 2023)

A facile “thick to thin” strategy for integrating high volumetric energy density and excellent flexibility into MXene/wood free-standing electrode for supercapacitors - Daotong Zhang; Kai Yang; Tao Zhang; Min Luo; Min Li; Zhao Li; Chaozheng Liu; Yiying Ling; Weimin Chen; Xiaoyan Zhou (Chemical Engineering Journal, 2023)

Chitosan-based carbon nitride-polydopamine‑silver composite dressing with antibacterial properties for wound healing - Chennan Liu; Junhong Ling; Li-Ye Yang; Xiao-kun Ouyang; Nan Wang (Carbohydrate Polymers, 2023)

Anaerobic–anoxic–oxic biological treatment of high-strength, highly recalcitrant polyphenylene sulfide wastewater - Hui Guo; Hai-Yong Yao; Qi-Qi Huang; Ting Li; De-Yang Show; Ming Ling; Yue-Gen Yan; Kuan-Yeow Show; Duu-Jong Lee (Bioresource Technology, 2023)

Liquid water determination by airborne millimeter cloud radar and in-situ size distribution measurements - Dongfei Zuo; Dantong Liu; Delong Zhao; Ling Yang; Yichen Chen; Wei Zhou; Mengyu Huang; Hui He; Ping Tian; Yuanmou Du; Wei Xiao; Ruijie Li; et al. (Atmospheric Research, 2023)

First evaluation of GPM-Era satellite precipitation products with new observations on the western Tibetan Plateau - Changhui Zhan; Yingying Chen; Kun Yang; Lazhu; Xu Zhou; Yaozhi Jiang; Xiaoyan Ling; Jiaxin Tian; Yan Wang; Xin Li; Hua Yang (Atmospheric Research, 2023)

Identification of structural variations related to drought tolerance in wheat (Triticum aestivum L.) - Jiajia Zhao; Xiaohua Li; Ling Qiao; Xingwei Zheng; Bangbang Wu; Meijun Guo; Meichen Feng; Zengjun Qi; Wude Yang; Jun Zheng (Theoretical and Applied Genetics, 2023)

Deep Sc-RNA sequencing decoding the molecular dynamic architecture of the human retina - Lulin Huang; Runze Li; Lin Ye; Shanshan Zhang; Huaping Tian; Mingyan Du; Chao Qu; Shujin Li; Jie Li; Mu Yang; Biao Wu; Ran Chen; et al. (Science China Life Sciences, 2023)

Fumigation activity of essential oils of Cinnamomum loureirii toward red imported fire ant workers - Huanling Xing; Yingqi Hu; Liupeng Yang; Jianhao Lin; Haiyi Bai; Yanqun Li; Rezwan Tanvir; Ling Li; Mei Bai; Zhixiang Zhang; Hanhong Xu; Hong Wu (Journal of Pest Science, 2023)

TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance - Juanjuan Zhao; Li Jia; YiJing Tao; Xu Zhao; Jing Yang; Yanxin Lu; Yaping Yan; Ling Mao; Lin Hu; Jia Lu; MengMeng Guo; Chao Chen; et al. (Inflammation Research, 2023)
Background Endotoxin tolerance (ET) is a protective mechanism in the process of sepsis, septic shock, and their sequelae including uncontrolled inflammation. Accumulating evidence has shown that peripheral T cells contribute to the induction of ET. However, what and how T-cell development contributes to ET inductions remain unclear. Methods Mice were intraperitoneally injected with LPS at a concentration of 5 mg/kg to establish an LPS tolerance model and were divided into two groups: a group examined 72 h after LPS injection (72-h group) and a group examined 8 days after LPS injection (8-day group). Injection of PBS was used as a control. We performed high-throughput sequencing to analyze the characteristics and changes of CD4 + SP TCR β CDR3 repertoires with respect to V direct to J rearrangement during the ET induction. Moreover, the proportion and proliferation, as well as surface molecules such as CD80 and CD86, of F4/80 + macrophages were analyzed using FCM. Furthermore, ACT assay was designed and administered by the tail vein into murine LPS-induced mouse model to evaluate the role of F4/80 + macrophages on the development of CD4 + SP thymocytes in ET condition. Results We found that the frequency and characteristics of the TCR β chain CDR3 changed obviously under condition of ET, indicating the occurrence of TCR rearrangement and thymocyte diversification. Moreover, the absolute numbers of F4/80 + macrophages, but not other APCs, were increased in thymic medulla at 72-h group, accompanied by the elevated function-related molecules of F4/80 + macrophages. Furthermore, adoptively transferred OVA 332-339 peptide-loaded macrophages into Rag-1 −/− mice induced the clone deletion of OVA-specific CD4 + SP, thereby ameliorating the pathology in lung tissue in LPS challenge. Conclusions These data reveal that the frequency and characteristics of the TCR β chain CDR3 undergo dynamic programming under conditions of LPS tolerance. Furthermore, the peripheral macrophages may be a key factor which carry peripheral antigen to thymic medulla and affect the negative selection of T-cell population, thereby contributing to the formation of ET. These results suggest that the clone selection in thymus in ET may confer protection against microbial sepsis.

circFLNA promotes intestinal injury during abdominal sepsis through Fas-mediated apoptosis pathway by sponging miR-766-3p - Ling Ye; Yuan Shi; Huifeng Zhang; Chao Chen; Jingjing Niu; Jianxu Yang; Zhifeng Li; Huanzhang Shao; Bingyu Qin (Inflammation Research, 2023)
Background Intra-abdominal infections are the second most common cause of sepsis in the intensive care unit. Intestinal epithelial injury due to abdominal sepsis results in a variety of pathological changes, such as intestinal bacteria and toxins entering the blood, leading to persistent systemic inflammation and multiple organ dysfunction. The increased apoptosis of intestinal epithelial cells induced by sepsis further exacerbates the progression of sepsis. Although several studies have revealed that circRNAs are involved in intestinal epithelial injury in sepsis, few studies have identified the roles of circRNAs in intestinal epithelial apoptosis. Methods We used laser capture microdissection to obtain purified epithelial cells located in intestinal crypts from four patients with abdominal sepsis induced by intestinal perforation and four samples from age and sex-matched non-septic patients. Microarray analysis of circRNAs was conducted to assess differentially expressed circRNAs between patients with and without sepsis. Lastly, in vitro and in vivo assays were performed to study the mechanism of circFLNA in intestinal epithelial apoptosis during sepsis. Results circFLNA was upregulated in the intestinal epithelium after abdominal sepsis induced by intestinal perforation. Inhibition of miR-766-3p impaired si-circFLNA-mediated inhibition of apoptosis and inflammation factor levels in lipopolysaccharide (LPS)-treated HIEC-6 cells. circFLNA aggravated apoptosis and inflammation through the Fas-mediated apoptosis pathway in both LPS-treated HIEC-6 cells and a mouse cecal ligation and puncture model. Conclusion Our findings showed that circFLNA promotes intestinal injury in abdominal sepsis through the Fas-mediated apoptosis pathway by sponging miR-766-3p. The circFLNA/miR-766-3p/Fas axis has potential as a novel therapeutic target for treating intestinal injury in sepsis.

Enhanced Lipid Productivity in Low-Starch Mutant of Monoraphidium sp. for Biodiesel Production - Yimeng Lin; Yunye Zhang; Yang Fan; Chang Li; Hongzhi Ling; Wenxiang Ping; Jingping Ge (BioEnergy Research, 2023)

Ambient nitrogen dioxide and cardiovascular diseases in rural regions: a time-series analyses using data from the new rural cooperative medical scheme in Fuyang, East China - Teng-Fei Dong; Zhen-Qiu Zha; Liang Sun; Ling-Li Liu; Xing-Yang Li; Yuan Wang; Xiang-Long Meng; Huai-Biao Li; Hong-Li Wang; Huan-Huan Nie; Lin-Sheng Yang (Environmental Science and Pollution Research, 2023)

CFD Simulation of Centrifugal Pump with Different Impeller Blade Trailing Edges - Hui Li; Yongjun Chen; Yang Yang; Shixin Wang; Ling Bai; Ling Zhou (Journal of Marine Science and Engineering, 2023)
The centrifugal pump is one of the most widely used types of power machinery in the field of ship and ocean engineering, and the shape of the impeller blade trailing edge has an important influence on their performance. To reveal the mechanism of the effect of different trailing edges on external performance, the internal flow of 16 types of impeller blade trailing edges of a centrifugal pump, consisting of Bezier trailing edges, rounding on the pressure side, cutting on the suction side, and the original trailing edge is studied by numerical simulation. The reverse flow, shaft power, and energy loss distribution in the impeller and diffuser along the streamwise direction are analyzed by calculating them on each micro control body sliced from the fluid domain. The entropy production theory and Ω-vortex identification method are used to display the magnitude and location of energy loss and the vortex structure. Finally, a static structural analysis of the impeller with different trailing edges is performed. The results show that different impeller trailing edges can clearly affect the efficiency of the pump, i.e., the thinner the trailing edge, the higher the efficiency, with the thickest model reducing efficiency by 5.71% and the thinnest model increasing efficiency by 0.59% compared to the original one. Changing the shape of the impeller trailing edge has a great influence on the reverse flow, shaft power, and energy loss near the impeller trailing edge and diffuser inlet but has little influence on the leading part of the impeller. The distribution of local entropy production rate, energy loss, and reverse flow along the streamwise direction shows similar rules, with a local maximum near the leading edge of the impeller due to the impact effect, and a global maximum near the impeller trailing edge resulting from strong flow separation and high vortex strength due to the jet-wake flow. Thinning the impeller trailing edge and smoothing its connection with the blade can reduce the vortex strength and entropy production near the impeller trailing edge and diffuser inlet, improve the flow pattern, and reduce energy loss, thus improving the pump efficiency. In all models, the maximum equivalent stress is less than 6.5 MPa and the maximum total deformation is less than 0.065mm. The results are helpful for a deeper understanding of the complex flow mechanism of the centrifugal pump with different blade trailing edges.

Identification of marine natural product Pretrichodermamide B as a STAT3 inhibitor for efficient anticancer therapy - Rui Li; Yue Zhou; Xinxin Zhang; Lujia Yang; Jieyu Liu; Samantha M. Wightman; Ling Lv; Zhiqing Liu; Chang-Yun Wang; Chenyang Zhao (Marine Life Science & Technology, 2023)
The Janus kinase (JAK)/signal transducer and activator of transcription 3 (STAT3) regulates the expression of various critical mediators of cancer and is considered as one of the central communication nodes in cell growth and survival. Marine natural products (MNP) represent great resources for discovery of bioactive lead compounds, especially anti-cancer agents. Through the medium-throughput screening of our in-house MNP library, Pretrichodermamide B, an epidithiodiketopiperazine, was identified as a JAK/STAT3 signaling inhibitor. Further studies identified that Pretrichodermamide B directly binds to STAT3, preventing phosphorylation and thus inhibiting JAK/STAT3 signaling. Moreover, it suppressed cancer cell growth, in vitro, at low micromolar concentrations and demonstrated efficacy in vivo by decreasing tumor growth in a xenograft mouse model. In addition, it was shown that Pretrichodermamide B was able to induce cell cycle arrest and promote cell apoptosis. This study demonstrated that Pretrichodermamide B is a novel STAT3 inhibitor, which should be considered for further exploration as a promising anti-cancer therapy.

Vitamin D serves as a modulator of immune organs in grass carp (Ctenopharyngodon idella) infected with Aeromonas hydrophila - Yao Zhang; Chao-Nan Li; Wei-Dan Jiang; Pei Wu; Yang Liu; Sheng-Yao Kuang; Ling Tang; Shu-Wei Li; Xiao-Wan Jin; Hong-Mei Ren; Xiao-Qiu Zhou; Lin Feng (Aquaculture, 2023)

RETRACTED: Boronic acid-modified bacterial cellulose microspheres as packing materials for enveloped virus removal - Zhiyang Lin; Linhan Li; Kaige Song; Bin Yang; Guoqing Zhou; Gengrong Zhang; Jiang Teng; Erlong Wang; Xiaoqiang Liu; Fei Ling; Gaoxue Wang; Tianqiang Liu (Science of The Total Environment, 2023)

Enhancements of dissociation of electrode materials in spent lithium-ion batteries by low-temperature heating pretreatment - Si-qi Jiang; Chun-chen Nie; Shun-xiang Shi; Yong-qiang Zhao; Xiang-guang Li; Chao-zhu Deng; Lu Yang; Ling Zhang; Xiang-nan Zhu (Process Safety and Environmental Protection, 2023)

Controlling effect and mechanism of burdock fructooligosaccharide against Alternaria fruit rot in blueberry during postharvest - Yajuan Wang; Jiaqi Wang; Yuxuan Li; Ling Yang; Bingxin Sun; Yunhe Zhang; Yufeng Xu; Xuerui Yan (Postharvest Biology and Technology, 2023)

A new phragmalin-type limonoid from the roots of Trichilia sinensis - Shou-Bai Liu; Jin-Ling Yang; Hui-Qin Chen; Cheng-min Yang; Hao Wang; Cai-Hong Cai; Jing-Zhe Yuan; Wen-Li Mei; Hao-Fu Dai (Phytochemistry Letters, 2023)

Functional analysis of 3 genes in xenobiotic detoxification pathway of Bursaphelenchus xylophilus against matrine - Yang Li; Bi Wu; Xin Hao; Jian Diao; Jingxin Cao; Ruina Tan; Wei Ma; Ling Ma (Pesticide Biochemistry and Physiology, 2023)

Are olefin aromatization reactions structure sensitive over Al pairs and single Al in H-ZSM-5 Zeolite? - Mengjiao Xing; Yunlei Chen; Jian Cao; Yuanlong Han; Zhichao Tao; Fei Wang; Kun Hao; Ling Zhang; Wentao Zheng; Hongwei Xiang; Yong Yang; Yongwang Li; et al. (Fuel, 2023)

A comparative study on the most effective machine learning model for blast loading prediction: From GBDT to Transformer - Qilin Li; Yang Wang; Yanda Shao; Ling Li; Hong Hao (Engineering Structures, 2023)

SWCNTs/Ag2Se film with superior bending resistance and enhanced thermoelectric performance via in situ compositing - Qin-Xue Hu; Wei-Di Liu; Li Zhang; Wei Sun; Han Gao; Xiao-Lei Shi; Yan-Ling Yang; Qingfeng Liu; Zhi-Gang Chen (Chemical Engineering Journal, 2023)

Microplastics-derived dissolved organic matters accelerate photodegradation of sulfamethazine in wastewater ultraviolet disinfection process - Zeyuan Yang; Peng Liu; Jian Wang; Ling Ding; Luqi Li; Hanzhong Jia; Tiecheng Wang; Xuetao Guo; Shixiang Gao (Chemical Engineering Journal, 2023)

Insights into reactive species generation and organics selective degradation in Fe-based heterogeneous Fenton-like systems: A critical review - Ling Li; Zhuo Yin; Min Cheng; Lei Qin; Shiyu Liu; Huan Yi; Mingming Zhang; Yukui Fu; Xiaofeng Yang; Xuerong Zhou; Guangming Zeng; Cui Lai (Chemical Engineering Journal, 2023)

Facile synthesis of spiro-core-based hole-transporting material for high-performance and stable perovskite solar cells - Kun-Mu Lee; Seid Yimer Abate; June Hung Yang; Wei-Hao Chiu; Seoungjun Ahn; Sie-Rong Li; Kang-Ling Liau; Yu-Tai Tao; Yan-Duo Lin (Chemical Engineering Journal, 2023)

Insights into the mechanism of elemental mercury removal via ferric chloride modified carbon Aerogel: An experimental and theoretical research - Jiachen Li; Tong Li; Fengting Li; Tao Jia; Jiang Wu; Sikai Wu; Yang Ling; Ping He; Xu Mao; Jie Dong (Chemical Engineering Journal, 2023)

Biofilm microenvironment response nanoplatform synergistically degrades biofilm structure and relieves hypoxia for efficient sonodynamic therapy - Heng Dong; Weijun Xiu; Ling Wan; Qiang Li; Yu Zhang; Meng Ding; Jingyang Shan; Kaili Yang; Zhaogang Teng; Lihui Yuwen; Yongbin Mou (Chemical Engineering Journal, 2023)