Characteristics of tailpipe volatile halogenated hydrocarbon (VHC) emissions from in-use vehicles during real-world driving - Hui Mei; Menglei Wang; Boqiang Jin; Rencheng Zhu; Yunjing Wang; Lulu Wang; Shunyi Li; Ruiqin Zhang; Xiaofeng Bao (Environmental Science and Pollution Research, 2021)

Risk assessment and ecotoxicological diagnosis of soil from a chemical industry park in Nanjing, China - Tong Zhang; Feng Liu; Xiezhi Yu; Xiaofeng Jiang; Yibin Cui; Mei Li (Ecotoxicology, 2021)

Methane Concentration in the Heartwood of Living Trees and Estimated Methane Emission on Stems in Upland Forests - Zhi-Ping Wang; Huan-Long Li; Hong-Hui Wu; Shi-Jie Han; Jian-Hui Huang; Xi-Mei Zhang; Xing-Guo Han (Ecosystems, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Effects of temperature on the locomotor performance and contraction properties of skeletal muscle from two Phrynocephalus lizards at high and low altitude - Zhiyi Niu; Mei Li; Peng Pu; Huihui Wang; Tao Zhang; Xiaolong Tang; Qiang Chen (Journal of Comparative Physiology B, 2021)

Triterpene saponins from tea seed pomace ( Camellia oleifera Abel) and their cytotoxic activity on MCF-7 cells in vitro - Xin-Fu Zhang; Ying-Ying Han; Tai-Mei Di; Li-Ping Gao; Tao Xia (Natural Product Research, 2021)

Do rapid photosynthetic responses protect maize leaves against photoinhibition under fluctuating light? - Mei-Yu Qiao; Ya-Jun Zhang; Li-An Liu; Lei Shi; Qing-Hu Ma; Wah Soon Chow; Chuang-Dao Jiang (Photosynthesis Research, 2021)

Application of Plant Print Identification Technology in Salt-resistant Soybean Breeding - Yan Li; Xia Li; Zi-qi Chen; Ying Ma; Guang-yu Yang; Ying Zhang; Ming-chun Sun; Li-hong Zhang; Jin-meng Chu; Jing-mei Lu; Jun Zhu; Ji-hong You (Journal of Plant Growth Regulation, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Protective effects of astaxanthin from Haematococcus pluvialis on the survival and oxidative stress of zebrafish embryos induced by microcystin-LR - Jing Dong; Chenlu Li; Dujuan Dai; Man Zhang; Yunni Gao; Xuejun Li; Mei Li; Jingxiao Zhang; Xianfeng Wang; Chuanjiang Zhou (Journal of Applied Phycology, 2021)

Removal of N,N-dimethylformamide by dielectric barrier discharge plasma combine with manganese activated carbon - Wenjiao Sang; Longjie Mei; Cheng Zhan; Qian Zhang; Xi Jin; Shaohui Zhang; Shiyang Zhang; Cuihua Li; Min Li (Environmental Science and Pollution Research, 2021)

Efficient Degradation of 2,4-Dichlorophenol on Activation of Peroxymonosulfate Mediated by MnO2 - Jingliang Liu; Fengxia An; Mei Li; Lu Yang; Jinzhong Wan; Shengtian Zhang (Bulletin of Environmental Contamination and Toxicology, 2021)

Evaluation of the RNA extraction methods in different Ginkgo biloba L. tissues - Xiao-lin Zhang; Xiao-li Huang; Jia Li; Mei Mei; Wan-qi Zeng; Xiu-jun Lu (Biologia, 2021)

A new ent -kaurane diterpene from Isodon henryi - Xue Jiang; Ling-Xia Zhang; Qing-Mei Feng; Hong Wu; Ya-Lin Liu; De-Qin Wang; Li-Ping Dai; Zhi-Min Wang (Natural Product Research, 2021)

Structural, Functional, and Molecular Imaging of Autism Spectrum Disorder - Xiaoyi Li; Kai Zhang; Xiao He; Jinyun Zhou; Chentao Jin; Lesang Shen; Yuanxue Gao; Mei Tian; Hong Zhang (Neuroscience Bulletin, 2021)

Restricted Feeding Resets Endogenous Circadian Rhythm in Female Mice Under Constant Darkness - Yue Mei; Huajing Teng; Zhigang Li; Cheng Zeng; Yuanyuan Li; Wei Song; Kaifan Zhang; Zhong Sheng Sun; Yan Wang (Neuroscience Bulletin, 2021)

Complete genome sequence of a novel citrus virus with characteristics of members of the family Tymoviridae - Liu Yang; Song Zhang; Shiqiang Mei; Qiyan Liu; Yan Zhou; Ruhui Li; Mengji Cao (Archives of Virology, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Inhibition of the p38 MAPK pathway attenuates renal injury in pregnant rats with acute necrotizing pancreatitis - Jiacheng Zhang; Fangchao Mei; Liang Zhao; Teng Zuo; Yupu Hong; Man Li; Jia Yu; Weixing Wang (Immunologic Research, 2021)

Effects of film mulching on the distribution of phthalate esters in wheat grains from dryland - Yingying Sun; Chao Li; Xinxin Zhang; Mei Shi; Zhaohui Wang (Environmental Science and Pollution Research, 2021)

Correction to: Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

LAI scale effect research based on compact airborne spectrographic imager data in the Heihe Oasis - Xiao-ai Dai; Chao Liu; Nai-wen Li; Mei-lian Wang; Yu-wei Yang; Xing-ping Yang; Shi-qi Zhang; Xu-wei He; Zheng-li Yang; Heng Lu; Jing-zhong Li; Ze-kun Wang (Journal of Mountain Science, 2021)

Nutrigenomics reveals potential genetic underpinning of diverse taste preference of Chinese men - Zhouhai Zhu; Junpu Mei; Silong Sun; Sheming Lu; Meng Li; Ying Guan; Ying Chen; Yuqiong Xu; Tao Zhang; Fengxue Shi; Xuemei Li; Mingming Miao; et al. (Genes & Genomics, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Aberrant expression of miR-199a in newborns with hypoxic-ischemic encephalopathy and its diagnostic and prognostic significance when combined with S100B and NSE - Min Li; Mei Ye; Guangyun Zhang (Acta Neurologica Belgica, 2021)

Overcoming diverse homologous recombinations and single chimeric guide RNA competitive inhibition enhances Cas9‐based cyclical multiple genes coediting in filamentous fungi - Youzhi Miao; Yanwei Xia; Yanqiong Kong; Han Zhu; Huiling Mei; Pan Li; Haichao Feng; Weibing Xun; Zhihui Xu; Nan Zhang; Dongyang Liu; Qirong Shen; et al. (Environmental Microbiology, 2021)
Summary Deciphering the complex cellular behaviours and advancing the biotechnology applications of filamentous fungi increase the requirement for genetically manipulating a large number of target genes. The current strategies cannot cyclically coedit multiple genes simultaneously. In this study, we firstly revealed the existence of diverse homologous recombination (HR) types in marker‐free editing of filamentous fungi, and then, demonstrated that sgRNA efficiency‐mediated competitive inhibition resulted in the low integration of multiple genetic sites during coediting, which are the two major obstacles to limit the efficiency of cyclically coediting of multiple genes. To overcome these obstacles, we developed a biased cutting strategy by Cas9 to greatly enhance the desired HR type and applied a new selection marker labelling strategy for multiple donor DNAs, in which only the donor DNA with the lowest sgRNA efficiency was labelled. Combined with these strategies, we successfully developed a convenient method for cyclically coediting multiple genes in different filamentous fungi. In addition, diverse HRs resulted in a useful and convenient one‐step approach for gene functional study combining both gene disruption and complementation. This research provided both a useful one‐step approach for gene functional study and an efficient strategy for cyclically coediting multiple genes in filamentous fungi.

Spatial prediction of soil calcium carbonate content based on Bayesian maximum entropy using environmental variables - Mei Shan; Shuang Liang; Hongchen Fu; Xiaoli Li; Yu Teng; Jingwen Zhao; Yaxin Liu; Chen Cui; Li Chen; Hai Yu; Shunbang Yu; Yanling Sun; et al. (Nutrient Cycling in Agroecosystems, 2021)

KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice - Hao-Ran Wang; Su-Wan Hu; Song Zhang; Yu Song; Xiao-Yi Wang; Lei Wang; Yang-Yang Li; Yu-Mei Yu; He Liu; Di Liu; Hai-Lei Ding; Jun-Li Cao (Neuroscience Bulletin, 2021)
Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury (CCI) in mice increased the firing activity and decreased the KCNQ channel-mediated M-currents in ventral tegmental area (VTA) DA neurons projecting to the nucleus accumbens (NAc). Chemogenetic inhibition of the VTA-to-NAc DA neurons alleviated CCI-induced thermal nociception. Opposite changes in the firing activity and M-currents were recorded in VTA DA neurons projecting to the medial prefrontal cortex (mPFC) but did not affect nociception. In addition, intra-VTA injection of retigabine, a KCNQ opener, while reversing the changes of the VTA-to-NAc DA neurons, alleviated CCI-induced nociception, and this was abolished by injecting exogenous BDNF into the NAc. Taken together, these findings highlight a vital role of KCNQ channel-mediated modulation of mesolimbic DA activity in regulating thermal nociception in the chronic pain state.

Spatial variation and fractionation of fluoride in tobacco-planted soils and leaf fluoride concentration in tobacco in Bijie City, Southwest China - Mei Wang; Long Zhang; Yanxiang Liu; Dan Chen; Lei Liu; Caibing Li; Kyong Ju Kang; Lingyu Wang; Zhenli He; Xiaoe Yang (Environmental Science and Pollution Research, 2021)

Different physiological responses of C3 and C4 plants to nanomaterials - Tonghao Bai; Peng Zhang; Zhiling Guo; Andrew J. Chetwynd; Mei Zhang; Muhammad Adeel; Mingshu Li; Kerui Guo; Ruize Gao; Jianwei Li; Yi Hao; Yukui Rui (Environmental Science and Pollution Research, 2021)

Study on the spatial-temporal differences and evolution of ecological security in the typical area of the Loess Plateau - Jiafeng Wen; Kang Hou; Haihong Li; Yue Zhang; Dan He; Ruochen Mei (Environmental Science and Pollution Research, 2021)

Effect of fermentation bed on bacterial growth in the fermentation mattress material and cecum of ducks - Jian- mei Wang; Xin- meng Gan; Fa-jun Pu; Wan- xia Wang; Min Ma; Ling-li Sun; Ji-wei Hu; Bo Hu; Rong-ping Zhang; Li-li Bai; Liang Li; He-he Liu (Archives of Microbiology, 2021)

Paenibacillus puerhi sp. nov., isolated from the rhizosphere soil of Pu-erh tea plants (Camellia sinensis var. assamica) - Rui-Juan Yang; De Zhou; Qiao-Mei Wang; Xing-Hua Wang; Wen-Jie Zhang; Li Zhuang; Xuan-Jun Wang; Liang Yan; Jie Lv; Jun Sheng (Archives of Microbiology, 2021)

Influence of major water conservation projects on river channels and shorelines in the middle and lower reaches of the Yangtze River - Yue-hua Jiang; He-qin Cheng; Quan-ping Zhou; Yun Li; Guo-qiang Yang; Yang Jin; Shi-jia Mei; Xuan Gu; Hong Zhang (Arabian Journal of Geosciences, 2021)

Two novel flavonoids from the leaves of Rhododendron dauricum L. with their inhibition of TNF-α production in LPS-induced RAW 264.7 cells - Chao Ye; Mei Jin; Chunshi Jin; Rongshen Wang; Jiaming Wang; Ying Zhang; Sainan Li; Jinfeng Sun; Wei Zhou; Gao Li (Natural Product Research, 2021)

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Supply chain carbon emission reductions and coordination when consumers have a strong preference for low-carbon products - Mei-lian Liu; Zong-huo Li; Sajid Anwar; Yun Zhang (Environmental Science and Pollution Research, 2021)

Biotransformation of Phlorizin by Eurotium cristatum to Increase the Antioxidant and Antibacterial Activity of Docynia indica Leaves - Jie Xie; Jiang Chen; Xue-ran Mei; Ming-jun Zhu; Xue-li Li; Juan Du; Xiao-yu Zhang (Current Microbiology, 2021)

Haplotype networks of Phycocalidia tanegashimensis (Bangiales, Rhodophyta) indicate a probable invasion from the South China Sea to Brazil - Wan Zhao; Lei Dong; Dang Diem Hong; Juliet Brodie; Wei-Zhou Chen; Dam Duc Tien; Wei Zhou; Qin-Qin Lu; Mei-Ru Zhang; Li-En Yang (Marine Biodiversity, 2021)

Adaptive Evolution of Chalcone Isomerase Superfamily in Fagaceae - Li-Mei Lin; Hong-Yu Guo; Xin Song; Duo-Duo Zhang; Yue-Hong Long; Zhao-Bin Xing (Biochemical Genetics, 2021)

Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation - Xiaoli Liu; Yan Gu; Yaoyao Bian; Danhong Cai; Yu Li; Ye Zhao; Zhaofeng Zhang; Mei Xue; Liang Zhang (Apoptosis, 2021)
Acute promyelocytic leukemia (APL) is a blood system disease caused by the accumulation of a large number of immature blood cells in bone marrow. Although the introduction of all- trans retinoic acid (ATRA) and arsenic has reached a high level of complete remission rate and 5-year disease-free survival rate, the occurrence of various adverse reactions still severely affects the quality of life of patients. As a natural product, honokiol (HNK) has the advantages of low toxicity and high efficiency, and it is a potential drug for the treatment of cancer. Since cancer cells can escape apoptotic cell death through multiple adaptive mechanisms, HNK, a drug that induces cancer cell death in a nonapoptotic way, has attracted much interest. We found that HNK reduced the viability of human APL cell line (NB4 cells) by inducing paraptosis-like cell death. The process was accompanied by excessive reactive oxygen species (ROS), mitochondrial damage, endoplasmic reticulum stress, and increased microtubule-associated protein 1 light chain 3 (LC3) processing. The inactivation of proteasome activity was the main cause of misfolded and unfolded protein accumulation in endoplasmic reticulum, such as LC3II/I and p62. This phenomenon could be alleviated by adding cycloheximide (CHX), a protein synthesis inhibitor. We found that mTOR signaling pathway participated in paraptosis-like cell death induced by HNK in an autophagy-independent process. Moreover, the mitogen-activated protein kinase (MAPK) signaling pathway induced paraptosis of NB4 cells by promoting endoplasmic reticulum stress. In summary, these findings indicate that paraptosis may be a new way to treat APL, and provide novel insights into the potential mechanism of paraptosis-like cell death.

Complex microbial communities inhabiting natural Cordyceps militaris and the habitat soil and their predicted functions - Xiao-Mei Zhang; De-Xiang Tang; Qing-Qing Li; Yuan-Bing Wang; Zhi-Hong Xu; Wen-Jun Li; Hong Yu (Antonie van Leeuwenhoek, 2021)

Rare taxa maintain the stability of crop mycobiomes and ecosystem functions - Chao Xiong; Ji‐Zheng He; Brajesh K. Singh; Yong‐Guan Zhu; Jun‐Tao Wang; Pei‐Pei Li; Qin‐Bing Zhang; Li‐Li Han; Ju‐Pei Shen; An‐Hui Ge; Chuan‐Fa Wu; Li‐Mei Zhang (Environmental Microbiology, 2021)
Summary Plants harbour highly diverse mycobiomes which sustain essential functions for host health and productivity. However, ecological processes that govern the plant–mycobiome assembly, interactions and their impact on ecosystem functions remain poorly known. Here we characterized the ecological role and community assembly of both abundant and rare fungal taxa along the soil–plant continuums (rhizosphere, phyllosphere and endosphere) in the maize–wheat/barley rotation system under different fertilization practices at two contrasting sites. Our results indicate that mycobiome assembly is shaped predominantly by compartment niche and host species rather than by environmental factors. Moreover, crop‐associated fungal communities are dominated by few abundant taxa mainly belonging to Sordariomycetes and Dothideomycetes, while the majority of diversity within mycobiomes are represented by rare taxa. For plant compartments, the abundant sub‐community is mainly determined by stochastic processes. In contrast, the rare sub‐community is more sensitive to host selection and mainly governed by deterministic processes. Furthermore, our results demonstrate that rare taxa play an important role in fungal co‐occurrence network and ecosystem functioning like crop yield and soil enzyme activities. These results significantly advance our understanding of crop mycobiome assembly and highlight the key role of rare taxa in sustaining the stability of crop mycobiomes and ecosystem functions.

Essential oil from Artemisia annua aerial parts: composition and repellent activity against two storage pests - Hong Liu; Shan-Shan Guo; Li Lu; Dian Li; Jun Liang; Zhong-Hui Huang; Yan-Mei Zhou; Wen-Juan Zhang; Shushan Du (Natural Product Research, 2021)

Transcriptome sequencing and analysis for the pigmentation of scale and skin in common carp (Cyprinus carpio) - Yu-Jie Zhao; Jun Xiao; Mei-Di Huangyang; Ran Zhao; Qi Wang; Yan Zhang; Jiong-Tang Li (Molecular Biology Reports, 2021)

Microtubule Stabilization Promotes Microcirculation Reconstruction After Spinal Cord Injury - Yang-Yang Duan; Yong Chai; Nai-Li Zhang; Dong-Mei Zhao; Cheng Yang (Journal of Molecular Neuroscience, 2021)
Spinal cord microcirculation plays an important role in maintaining the function of spinal cord neurons and other cells. Previous studies have largely focused on the ability of microtubule stabilization to inhibit the fibroblast migration and promote axon regeneration after spinal cord injury (SCI). However, the effect of microtubule stabilization treatment on microcirculation reconstruction after SCI remains unclear. By using immunofluorescence, we found that microtubule stabilization treatment improved microcirculation reconstruction via increasing the number of microvessels, pericytes, and the perfused microvessels after SCI. To clarify the underlying mechanisms, rat brain microvascular endothelial cells and pericytes were subjected to glucose oxygen deprivation. By using flow cytometry and western blotting, we found that microtubule stabilization treatment inhibited apoptosis and migration of endothelial cells and pericytes but promoted proliferation and survival of endothelial cells and pericytes through upregulated expression of vascular endothelial growth factor A (VEGFA), VEGF receptor 2, platelet-derived growth factor-B (PDGFB), PDGF receptor β, and angiopoietin-1 after SCI. Taken together, this study provides evidence for the mechanisms underlying the promotion of microcirculation reconstruction after SCI by microtubule stabilization treatment. Importantly, this study suggests the potential of microtubule stabilization as a therapeutic target to reduce microcirculation dysfunction after SCI in the clinic.

Neobacillus sedimentimangrovi sp. nov., a Thermophilic Bacterium Isolated from Mangrove Sediment - Rong Tang; Qi Zhang; Manik Prabhu Narsing Rao; Guo-Hong Liu; Jian-Mei Che; Min Lei; Bo Liu; Wen-Jun Li; Shun-Gui Zhou (Current Microbiology, 2021)

Comparison of Class 2 Integron Integrase Activities - Xiaotong Wang; Nana Kong; Mei Cao; Long Zhang; Muzhen Sun; Linlin Xiao; Gang Li; Quhao Wei (Current Microbiology, 2021)

Lentibacillus saliphilus. sp. nov., a moderately halophilic bacterium isolated from a saltern in Korea - Yun Wang; Gang-Qiang Jiang; Hong-Ping Lin; Peng Sun; Hong-Yan Zhang; Dong-Mei Lu; Li-Yun Wang; Chang-Jin Kim; Shu-Kun Tang (Archives of Microbiology, 2021)

A global analysis on the systemic effects of antibiotics in cultured fish and their potential human health risk: a review - Samwel Mchele Limbu; Li‐Qiao Chen; Mei‐Ling Zhang; Zhen‐Yu Du (Reviews in Aquaculture, 2021)
The rearing of fish in intensive systems reduces their immunity leading to eruption of diseases, consequently prompting the use of antibiotics. Antibiotics are currently used in cultured fish globally to treat/prevent diseases. On the one hand, antibiotics used in aquaculture help to improve fish health by killing or inhibiting pathogenic bacteria proliferation. However, on the other hand, they cause multiple side effects. To date, information on systemic effects of antibiotics in cultured fish is scattered and their potential human health risk remains elusive. This review critically analyses and discusses the available information in the literature on the positive and negative effects of antibiotics in cultured fish and their potential human health risk via fish consumption. The review found 44 different antibiotics dominated by oxytetracycline were studied in various fish species worldwide. Antibiotics used in global aquaculture either decrease or increase fish growth and survival rates. They induce oxidative stress, which affect antioxidant and detoxification responses and cause host–microbiota dysbiosis. These changes compromise the fish immunity system, which ultimately lead to cellular damage. The toxicities generated inhibit the fish aerobic glycolysis, suppress lipogenesis and fatty acid β‐oxidation while increase energy demand by initiating gluconeogenesis and anaerobic glycolysis. Consumption of fish treated with antibiotics causes human health risk. Future studies are required on agents to restore dysfunctions induced by antibiotics in cultured fish, while attempts to limit their utilisation in aquaculture production are underway. [Correction added on 21 November 2020, after first online publication: The abstract has been amended to clarify the scope of the review.]

Report of epibenthic macrofauna found from Haima cold seeps and adjacent deep-sea habitats, South China Sea - Dong Dong; Xinzheng Li; Mei Yang; Lin Gong; Yang Li; Jixing Sui; Zhibin Gan; Qi Kou; Ning Xiao; Junlong Zhang (Marine Life Science & Technology, 2021)
This work reports on a preliminary taxonomic study of epibenthic macroinvertebrates collected or observed by underwater video at the Haima cold seeps and in adjacent deep-sea habitats, including a mud volcano field and Ganquan Plateau, during an expedition in the South China Sea by the Chinese-manned submersible Shenhai Yongshi in May 2018. A total of 41 species belonging to 6 phyla were identified, among which 34 species were collected from the Haima cold seeps. Mollusks and crustaceans that are specialized in reducing habitats were predominant in biotopes of the Haima cold seeps, whereas sponges and cold-water corals and their commensals were prominent in communities of the mud volcano field and the slopes of Ganquan Plateau. The distribution and faunal composition of each taxonomic group are discussed.

The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish - Si-Lan Han; Yan Liu; Samwel M. Limbu; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

Genetic Diversity Assessment of a Chinese Medicinal Endemic Species, Aspidopterys obcordata var. obcordata, by Combined Molecular Marker Methods (ISSR & SRAP) - Mei-Fang Song; Yan-Hong Guan; Yue Zhang; Hai-Tao Li; Li-Xia Zhang; Zhong-Lian Zhang (Biochemical Genetics, 2021)

Retraction Note to: NPC-16, a novel naphthalimide–polyamine conjugate, induced apoptosis and autophagy in human hepatoma HepG2 cells and Bel-7402 cells - Song-qiang Xie; Qian Li; Ya-hong Zhang; Jian-hong Wang; Zi-hou Mei; Jin Zhao; Chao-jie Wang (Apoptosis, 2021)

Diversity and potential biogeochemical impacts of viruses in bulk and rhizosphere soils - Li Bi; Dan‐Ting Yu; Shuai Du; Li‐Mei Zhang; Li‐Yu Zhang; Chuan‐Fa Wu; Chao Xiong; Li‐Li Han; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Viruses can affect microbial dynamics, metabolism and biogeochemical cycles in aquatic ecosystems. However, viral diversity and functions in agricultural soils are poorly known, especially in the rhizosphere. We used virome analysis of eight rhizosphere and bulk soils to study viral diversity and potential biogeochemical impacts in an agro‐ecosystem. The order Caudovirales was the predominant viral type in agricultural soils, with Siphoviridae being the most abundant family. Phylogenetic analysis of the terminase large subunit of Caudovirales identified high viral diversity and three novel groups. Viral community composition differed significantly between bulk and rhizosphere soils. Soil pH was the main environmental driver of the viral community structure. Remarkably, abundant auxiliary carbohydrate‐active enzyme (CAZyme) genes were detected in viromes, including glycoside hydrolases, carbohydrate esterases and carbohydrate‐binding modules. These results demonstrate that virus‐encoded putative auxiliary metabolic genes or metabolic genes that may change bacterial metabolism and indirectly contribute to biogeochemical cycling, especially carbon cycling, in agricultural soil.

Unconfined Compressive Properties of Fiber-Stabilized Coastal Cement Clay Subjected to Freeze–Thaw Cycles - Na Li; Yalan Zhu; Fang Zhang; Sin Mei Lim; Wangyi Wu; Wei Wang (Journal of Marine Science and Engineering, 2021)
This study aimed to investigate the feasibility of using polypropylene fiber-cement-stabilized coastal clay as base-course material or foundation material for city sustainable development by assessing its mechanical performance. The influence of the number of freeze–thaw cycles and curing ages on the mechanical properties of ordinary cemented clay (OCC) and polypropylene fiber-cemented clay (PCC) was investigated by using unconfined compressive test. The experimental results show that the addition of fiber with 1% content can increase the strength as well as the ductility of cemented clay by 12.5% and 15.6%, respectively. The strength of PCC and OCC at 22d age was 1.5 times than at 7d age. Under differently timed freeze–thaw cycles, the mechanical performance of PCC is improved, and, better than that, OCC improves by 11.8% in strength, 16.5% in strain and by 5% in degree of damage, indicating that fiber can improve the freeze–thaw resistance of cemented clay. The frost resistance of PCC and OCC increases with the increase in curing age. Finally, the variation of strength of OCC was explained through the change of micro-structure while the strength enhancing mechanism of polypropylene fiber for cemented clay was also revealed.

Diterpenoid and triterpenoid glycosides from Clinopodium chinense - Ling-Xia Qu; Yong-Qiao Liu; Yang Wang; Hong Wang; Xue-Li Huang; Mei-Ling Zhang; Yong-Xiao Mou; Tun-Hai Xu; Yin-Di Zhu (Natural Product Research, 2021)

A holistic strategy for discovering structural analogues of drug residues in meat using characteristic structural fragments filtering by high-resolution Orbitrap mass spectrometry - Xiao-Min Liu; Xiu-Li Xu; Xue-Mei Nie; Xue-Song Feng; Feng Zhang (Food Additives & Contaminants: Part A, 2021)

Performance evaluation of ensemble learning techniques for landslide susceptibility mapping at the Jinping county, Southwest China - Xudong Hu; Hongbo Mei; Han Zhang; Yuanyuan Li; Mengdi Li (Natural Hazards, 2021)

Description of Salinimonas profundi sp. nov., a deep-sea bacterium harboring a transposon Tn6333 - Dao-Feng Zhang; Xi-Wen Cui; Wen-Jun Li; Xiao-Mei Zhang; Hua-Peng Xue; Jian-Ke Huang; Ai-Hua Zhang (Antonie van Leeuwenhoek, 2021)

Flavonoids as key bioactive components of Oxytropis falcata bunge, a traditional anti-inflammatory and analgesic Tibetan medicine - Mei-Rong Zhang; Kan Jiang; Jun-Li Yang; Yan-Ping Shi (Natural Product Research, 2020)

A novel, validated, and plant height-independent QTL for spike extension length is associated with yield-related traits in wheat - Cong Li; Huaping Tang; Wei Luo; Xuemei Zhang; Yang Mu; Mei Deng; Yaxi Liu; Qiantao Jiang; Guoyue Chen; Jirui Wang; Pengfei Qi; Zhien Pu; et al. (Theoretical and Applied Genetics, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Identification, tissue distribution, periprandial expression, and anorexigenic effect of spexin in Siberian sturgeon, Acipenser baeri - Zhengzhi Tian; Shaoqi Xu; Mei Wang; Ya Li; Hu Chen; Ni Tang; Bin Wang; Xin Zhang; Zhiqiong Li (Fish Physiology and Biochemistry, 2020)

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

LncRNA A2M-AS1 lessens the injury of cardiomyocytes caused by hypoxia and reoxygenation via regulating IL1R2 - Xue-Lian Song; Fei-Fei Zhang; Wen-Jing Wang; Xin-Ning Li; Yi Dang; Ying-Xiao Li; Qian Yang; Mei-Jing Shi; Xiao-Yong Qi (Genes & Genomics, 2020)

A new demethyl abietane diterpenoid from the roots of Tripterygium wilfordii - Peng Li; Shao-Xin Shen; Ling-Xue Liu; Jian-Hua Xu; Xin-Hua Ma; Dong-Mei Shi; Zhi-Qiang Zhang (Natural Product Research, 2020)

Cascade marker removal algorithm for thyroid ultrasound images - Xiang Ying; Yulin Zhang; Mei Yu; Xi Wei; Jialin Zhu; Jie Gao; Zhiqiang Liu; Hongqian Shen; Ruixuan Zhang; Xuewei Li; Ruiguo Yu (Medical & Biological Engineering & Computing, 2020)

Whether the carbon emission from green roofs can be effectively mitigated by recycling waste building material as green roof substrate during five-year operation? - Liangqian Fan; Jingting Wang; Xiaoling Liu; Hongbing Luo; Ke Zhang; Xiaoying Fu; Mei Li; Xiaoting Li; Bing Jiang; Jia Chen; Shuzhi Fu; You Mo; et al. (Environmental Science and Pollution Research, 2020)

Characteristics of methane emissions in the Living Water Garden in Chengdu City from 2012 to 2017 - Ru Xue; Xiaoling Liu; Xiaoying Fu; Hongbing Luo; Ke Zhang; Bruce C. Anderson; Mei Li; Bo Huang; Lijuan Yu; Xiaoting Li; Shuzhi Fu; Aiping Pu; et al. (Environmental Science and Pollution Research, 2020)

Deinococcus detaillensis sp. nov., isolated from humus soil in Antarctica - Kun Zhang; Jing Zhu; Shuai Li; Manik Prabhu Narsing Rao; Ning-Mei Li; Ang-Yang Guo; Zhao Jiang; Qi-Yong Tang; Yi Wan; Zhi-Dong Zhang; Wen-Jun Li (Archives of Microbiology, 2020)

Two new compounds, Talaromycin A and B, isolated from an endophytic fungus, Talaromyces aurantiacus - Yi-Fei Zhang; Zhong-Duo Yang; Xing Yang; Li-Jun Yang; Xiao-Jun Yao; Zong-Mei Shu (Natural Product Research, 2020)

New cadinane sesquiterpenoids from Mikania micrantha - Yao Zhang; You-Mei Zeng; You-Kai Xu; Shu-Qi Wu; Shen Li; Hai-Yan Tian; Sheng Yin (Natural Product Research, 2020)

Circ_0068655 Promotes Cardiomyocyte Apoptosis via miR-498/PAWR Axis - Qiaoying Chai; Mingqi Zheng; Le Wang; Mei Wei; Yajuan Yin; Fangfang Ma; Xinping Li; Haijun Zhang; Gang Liu (Tissue Engineering and Regenerative Medicine, 2020)

Creation of fertility-restored materials for Ogura CMS in Brassica oleracea by introducing Rfo gene from Brassica napus via an allotriploid strategy - Hai-long Yu; Zhi-yuan Li; Wen-jing Ren; Feng-qing Han; Li-mei Yang; Mu Zhuang; Hong-hao Lv; Yu-mei Liu; Zhi-yuan Fang; Yang-yong Zhang (Theoretical and Applied Genetics, 2020)
Key message Ogura CMS fertility-restored materials, with 18 chromosomes, normal seed setting, stable fertility and closer genetic background to the parent Chinese kale, were successfully developed in B. oleracea via a triploid strategy for the first time. Abstract Ogura cytoplasmic male sterility (CMS) is the most widely used sterile type in seed production for commercial hybrids of Brassica oleracea vegetables. However, the natural Ogura CMS restorer line has not been found in B. oleracea crops. In this study, the triploid strategy was used with the aim to create euploid B. oleracea progenies with the Rfo gene. The allotriploid AAC hybrid YL2 was used as a male parent to backcross with Ogura CMS Chinese kale. After successive backcrosses, the BC 2 Rfo -positive individual 16CMSF2-11 and its BC 3 progenies, with 18 chromosomes, were developed, which were morphologically identical to the parent Chinese kale. Compared with F 1 and BC 1 plants, it showed stable fertility performance, and regular meiosis behavior and could produce seeds normally under natural pollination. The genomic composition analysis of Rfo -positive progenies by using molecular markers showed that more than 87% of the C-genome components of BC 3 Rfo -progenies recovered to the parent Chinese kale, while most or all of the A n -genome segments were lost in 16CMSF2-11 and its progenies. The results suggested that the genetic background of Rfo -positive individuals was closer to that of the parent Chinese kale along with backcrossing. Hereof, the Ogura CMS fertility-restored materials of Chinese kale were successfully created via triploid strategy for the first time, providing a bridge for utilizing the Ogura CMS B. oleracea germplasm in the future. Moreover, our study indicates that the triploid strategy is effective for transferring genes from B. napus into B. oleracea .

The combinatory effects of natural products and chemotherapy drugs and their mechanisms in breast cancer treatment - Yubo Zhang; Huajun Li; Jing Zhang; Chaoran Zhao; Shuai Lu; Jinping Qiao; Mei Han (Phytochemistry Reviews, 2020)

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway - Jia-Ru Wang; Tian-Zhu Li; Cheng Wang; Shu-Mei Li; Ying-Hua Luo; Xian-Ji Piao; Yu-Chao Feng; Yi Zhang; Wan-Ting Xu; Yu Zhang; Tong Zhang; Shi-Nong Wang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Upregulation of long non-coding RNA MEG3 in type 2 diabetes mellitus complicated with vascular disease: a case–control study - Wei-wei Chang; Liu Zhang; Xin-ming Yao; Yan Chen; Li-jun Zhu; Zheng-mei Fang; Ying Zhao; Ying-shui Yao; Yue-long Jin (Molecular and Cellular Biochemistry, 2020)

Variation of soil nitrate and bacterial diversity along soil profiles in manure disposal maize field and adjacent woodland - Yujia Cai; Ju-Pei Shen; Hong J. Di; Li-Mei Zhang; Chengjun Zhang; Ji-Zheng He (Journal of Soils and Sediments, 2020)

Comparing GWAS and Brain Structure-Specific Gene Expression Profiles Identifies Psychiatric Disorder-Related Brain Structures at Different Developmental Stages - Xin Qi; Cuiyan Wu; Yanan Du; Shiqiang Cheng; Yan Wen; Mei Ma; Chujun Liang; Li Liu; Bolun Cheng; Lu Zhang; Ping Li; Feng Zhang (Neuroscience Bulletin, 2020)

Vitamin D receptor gene methylation in patients with hand, foot, and mouth disease caused by enterovirus 71 - Ya-Ping Li; Hui-Ling Deng; Wen-Jun Wang; Mu-Qi Wang; Mei Li; Yu-Feng Zhang; Jun Wang; Shuang-Suo Dang (Archives of Virology, 2020)

An improved Gaussian frequency domain sparse inversion method based on compressed sensing - Yang Liu; Jun-Hua Zhang; Yan-Guang Wang; Li-Bin Liu; Hong-Mei Li (Applied Geophysics, 2020)

Impaired peroxisomal fat oxidation induces hepatic lipid accumulation and oxidative damage in Nile tilapia - Yan Liu; Si-Lan Han; Yuan Luo; Ling-Yu Li; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2020)

Prenatal di-(2-ethylhexyl) phthalate maternal exposure impairs the spatial memory of adult mouse offspring in a phase- and gender-dependent manner - Ling-Li Zhao; Ru Shen; Cong-Cong Sun; Shan-Yu Zhang; Bo Wang; Mei-Fang Sun; De-Xiang Xu (Environmental Science and Pollution Research, 2020)

Pseudomonas Saliphila sp. nov., a Bacterium Isolated from Oil-Well Production Water in Qinghai Oilfield of China - Xiao-Juan Zhang; Hong-Can Liu; Yu-Guang Zhou; Xiao-Lei Wu; Yong Nie; Qi-Rui Li; Mei-Zhu Wang; Liang Zhao; Man Cai; Ying-Qian Kang (Current Microbiology, 2020)

High throughput solid-phase screening of bacteria with cyclic amino alcohol deamination activity for enantioselective synthesis of chiral cyclic β-amino alcohols - Ya-Wen Chang; Jian-Dong Zhang; Xiao-Xiao Yang; Jing Li; Li-Li Gao; Shuang-Ping Huang; Xing-Mei Guo; Cao-Feng Zhang; Hong-Hong Chang; Jian-He Xu (Biotechnology Letters, 2020)

Isolation and identification of two new compounds from the Penicillium sp. SYPF7381 - Qing-Mei Feng; Xing-Yu Li; Bing-Xin Li; Tian-Yuan Zhang; Hai-Feng Wang; Meng-Yue Zhang; Ying-Ying Wu; Gang Chen; Yi-Xuan Zhang; Yue-Hu Pei (Natural Product Research, 2020)

Deregulated miR-384 serves as a biomarker in neonatal hypoxic-ischemic encephalopathy and alleviates microglia-mediated neuroinflammation - Guangyun Zhang; Mei Ye; Min Li (Molecular Biology Reports, 2020)

Identification and validation of reference genes for real-time RT-PCR in Aphelenchoides besseyi - Junyi Li; Zixu Zhang; Chunling Xu; Dongwei Wang; Mei Lv; Hui Xie (Molecular Biology Reports, 2020)
Fragments of four candidate reference genes of Aphelenchoides besseyi , including actin , glyceraldehyde-3-phosphate dehydrogenase ( GAPDH ) , ubiquitin conjugating-3 enzyme ( UBC ) and alpha-tubulin ( α-tubulin ) were cloned from the transcriptome database of A . besseyi . The expression level of these four candidate reference genes and a commonly used reference gene of A. besseyi ( 18S rRNA ) in three experimental conditions, including the four life stages (female, male, juvenile and egg) of two populations and the mixed-stage nematodes of four populations with different origins and hosts were analyzed by RT-qPCR. The expression stability of the five candidate reference genes under the three experimental conditions was analyzed by ΔCt, geNorm, NormFinder and RefFinder respectively. The analysis results of ΔCt, geNorm, NormFinder and RefFinder all indicated that UBC was the gene with the highest average ranking of stability. In conclusion, the expression stability of UBC was optimal under the three experimental conditions, indicating that UBC could be used as a suitable reference gene instead of 18S rRNA in the RT-qPCR analysis for A. besseyi.

SNX-2112, an Hsp90 inhibitor, suppresses cervical cancer cells proliferation, migration, and invasion by inhibiting the Akt/mTOR signaling pathway - Liang-Shun Fu; Hong-Hong Qiu; Min Liu; Liu-Bing Hu; Yan Wang; Peng-Chao Zhang; Man-Mei Li; Yi-Fei Wang; Zhong Liu (Medicinal Chemistry Research, 2020)

Sugar transporter genes in grass carp (Ctenopharyngodon idellus): molecular cloning, characterization, and expression in response to different stocking densities - Xiao Liang; Fengying Yan; Yu Gao; Mei Xiong; Haishan Wang; Kommaly Onxayvieng; Rong Tang; Li Li; Xi Zhang; Wei Chi; Marina Piria; Mirna Mrkonjić Fuka; et al. (Fish Physiology and Biochemistry, 2020)

Epidemiology and HBGA-susceptibility investigation of a G9P[8] rotavirus outbreak in a school in Lechang, China - Lun-Ai Guo; Meng Zhang; Yu-zhen Hou; Haitao Hu; Ling Fang; Ming Tan; Qiong Huang; Hui Li; Li-Mei Sun; Xi Jiang; Wen-Fang Tan; Shixing Tang; et al. (Archives of Virology, 2020)

A mycophenolic acid derivative from the fungus Penicillium sp. SCSIO sof101 - Xiaoxian Song; Ruxia Tu; Xiaoli Mei; Silan Wu; Bo Lan; Li Zhang; Xianqin Luo; Jianyi Liu; Minghe Luo (Natural Product Research, 2020)

Detection of serum IgM and IgG for COVID-19 diagnosis - Ling Zhong; Junlan Chuan; Bo Gong; Ping Shuai; Yu Zhou; Yi Zhang; Zhilin Jiang; Dingding Zhang; Xiaoqi Liu; Shi Ma; Yi Huang; He Lin; et al. (Science China Life Sciences, 2020)

Physiological and proteomic responses of mangrove plant Avicennia marina seedlings to simulated periodical inundation - Huan Li; Zan Li; Zhi-Jun Shen; Mei-Rong Luo; Yi-Ling Liu; Ming-Yue Wei; Wen-Hua Wang; Ying-Ying Qin; Chang-Hao Gao; Ke-Ke Li; Qian-Su Ding; Shan Zhang; et al. (Plant and Soil, 2020)

Analysis of Myoglobin Stability and Bacterial Community Diversity in Mutton Chop Rolls During Cold Preservation - Xue-Qi Zhang; Tao Jiang; Na Guo; Li Bai; Dong-Mei Zhao (Current Microbiology, 2020)

Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs. 3 doses in young women - Yue-Mei Hu; Meng Guo; Chang-Gui Li; Kai Chu; Wen-Gang He; Jing Zhang; Jian-Xiang Gu; Juan Li; Hui Zhao; Xiang-Hong Wu; BiZhen Lin; Zhi-Jie Lin; et al. (Science China Life Sciences, 2020)

Naturally Occurring Antibodies to Tau Exists in Human Blood and Are Not Changed in Alzheimer’s Disease - Zhong-Yuan Yu; Wei-Wei Li; Hai-Mei Yang; Noralyn B. Mañucat-Tan; Jun Wang; Ye-Ran Wang; Bin-Lu Sun; Zi-Cheng Hu; Li-Li Zhang; Liang Tan; Juan Deng; Yu-Hui Liu (Neurotoxicity Research, 2020)

Aluminum-induced “mixed” cell death in mice cerebral tissue and potential intervention - Yan-xia Hao; Mei-qin Li; Jing-si Zhang; Qin-li Zhang; Xia Jiao; Xiu-liang Ji; Huan Li; Qiao Niu (Neurotoxicity Research, 2020)

Myelin Deficits Caused by Olig2 Deficiency Lead to Cognitive Dysfunction and Increase Vulnerability to Social Withdrawal in Adult Mice - Xianjun Chen; Fei Wang; Jingli Gan; Zhonghua Zhang; Xuejun Liang; Tao Li; Nanxin Huang; Xiaofeng Zhao; Feng Mei; Lan Xiao (Neuroscience Bulletin, 2020)

High-carbohydrate diet promotes the adaptation to acute hypoxia in zebrafish - Qiang Ma; Chun-Ting Hu; Junjiayu Yue; Yuan Luo; Fang Qiao; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2020)

An empirical study on energy utilization efficiency, economic development, and sustainable management - Xin-Xin Pan; Mei-Lan Chen; Li-Meng Ying; Fang-Fang Zhang (Environmental Science and Pollution Research, 2020)

Evaluating the Genetic Correlations Between Left-Handedness and Mental Disorder Using Linkage Disequilibrium Score Regression and Transcriptome-Wide Association Study - Bolun Cheng; Chujun Liang; Ping Li; Li Liu; Shiqiang Cheng; Mei Ma; Lu Zhang; Xin Qi; Yan Wen; Feng Zhang (Biochemical Genetics, 2020)

Polymorphisms in arsenic (+ 3 oxidation state) methyltransferase (AS3MT) predict the occurrence of hyperleukocytosis and arsenic metabolism in APL patients treated with As2O3 - Wen-Sheng Liu; Xin-Yu Wang; Jing Lu; Ying-Mei Zhang; Xiang-Mei Ye; Jin-Mei Li; Qi-Lei Zhao; Zhi-Qiang Wu; Jin Zhou; Xin Hai (Archives of Toxicology, 2020)

Scorpion Venom Heat-Resistant Peptide is Neuroprotective against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway - Xu-Gang Wang; Dan-Dan Zhu; Na Li; Yue-Lin Huang; Ying-Zi Wang; Ting Zhang; Chen-Mei Wang; Bin Wang; Yan Peng; Bi-Ying Ge; Shao Li; Jie Zhao (Neuroscience Bulletin, 2020)

The inhibition of miR-17-5p promotes cortical neuron neurite growth via STAT3/GAP-43 pathway - Liang Zhang; Zhijie Wang; Bo Li; Ziwei Xia; Xin Wang; Yucai Xiu; Zheng Zhang; Chuanjie Chen; Hong Song; Wenhua Li; Mei Yu; Meiling Zhang; et al. (Molecular Biology Reports, 2020)

DNA stable isotope probing revealed no incorporation of 13CO2 into comammox Nitrospira but ammonia-oxidizing archaea in a subtropical acid soil - Zi-Yang He; Ju-Pei Shen; Li-Mei Zhang; Hua-Jing Tian; Bing Han; Hong-Jie Di; Ji-Zheng He (Journal of Soils and Sediments, 2020)

Microbial methane production is affected by secondary metabolites in the heartwood of living trees in upland forests - Huan-Long Li; Xi-Mei Zhang; Feng-Dan Deng; Xing-Guo Han; Chun-Wang Xiao; Shi-Jie Han; Zhi-Ping Wang (Trees, 2020)

Plasma biomarkers and plaque strain predict long-term cardiovascular events in patients with acute coronary syndrome - Mingjun Xu; Xiaobo Hu; Lin Wang; Wei Zhang; Lindi Wu; Jifu Li; Yuguo Chen; Pengfei Zhang; Haijun Su; Yaling Han; Cheng Zhang; Mei Zhang; et al. (Science China Life Sciences, 2020)

Co-expression Network of mRNAs and lncRNAs Regulated by Stress-Linked Behavioral Assays - Jianghong Zhang; Meiying Xue; Yue Mei; Zhigang Li; Zeng Ceng; Yuanyuan Li; Yi Zhang; Na Li; Huajing Teng; Zhong Sheng Sun; Yan Wang (Psychopharmacology, 2020)

Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression - Brandy Garzel; Tao Hu; Linhao Li; Yuanfu Lu; Scott Heyward; James Polli; Lei Zhang; Shiew-Mei Huang; Jean-Pierre Raufman; Hongbing Wang (Pharmaceutical Research, 2020)

Tillage practices improve rice yield and soil phosphorus fractions in two typical paddy soils - Waqas Ahmed; Muhammad Qaswar; Huang Jing; Dong Wenjun; Sun Geng; Liu Kailou; Meng Ying; Tang Ao; Sun Mei; Li Chao; Xu Yongmei; Sehrish Ali; et al. (Journal of Soils and Sediments, 2020)

Developing stripe rust resistant wheat (Triticum aestivum L.) lines with gene pyramiding strategy and marker-assisted selection - Rong Liu; Jing Lu; Min Zhou; Shigang Zheng; Zehou Liu; Chihong Zhang; Mei Du; Minxiu Wang; Yunfang Li; Yu Wu; Lei Zhang (Genetic Resources and Crop Evolution, 2020)

Production of waxy tetraploid wheat (Triticum turgidum durum L.) by EMS mutagenesis - Siyu Li; Xiaojuan Zhong; Xuteng Zhang; Md. Mostafijur Rahman; Jingyu Lan; Huaping Tang; Pengfei Qi; Jian Ma; Jirui Wang; Guoyue Chen; Xiujin Lan; Mei Deng; et al. (Genetic Resources and Crop Evolution, 2020)

Inhibition of intestinal lipases alleviates the adverse effects caused by high-fat diet in Nile tilapia - Yu-Xue Zhang; Zhe-Yue Jiang; Si-Lan Han; Ling-Yu Li; Fang Qiao; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2020)

Effectiveness analysis of the prediction of regional debris flow susceptibility in post-earthquake and drought site - Ning-sheng Chen; Yong Zhang; Shu-feng Tian; Ming-feng Deng; Tao Wang; Li-hong Liu; Mei Liu; Gui-sheng Hu (Journal of Mountain Science, 2020)

Comparison between two kinds of natural pollen traps in tropical China: ants’ nests on tree branches versus surface soil - Zhi-Yong Zhang; Feng-Chun Yang; Dong-Mei Cheng; David K. Ferguson; Wan Hu; Yue-Zhuo Li; Cheng-Sen Li (Palynology, 2020)

Evaluation of the genetic diversity of mango (Mangifera indica L.) seedling germplasm resources and their potential parents with start codon targeted (SCoT) markers - Li Zhou; Xin-Hua He; Hai-Xia Yu; Mei-Yan Chen; Yan Fan; Xiu-Juan Zhang; Zhong-Bing Fang; Cong Luo (Genetic Resources and Crop Evolution, 2020)

Valuing urban air quality: a hedonic price analysis in Beijing, China - Yingdan Mei; Li Gao; Jiawei Zhang; Jiahao Wang (Environmental Science and Pollution Research, 2020)

Effect of long-term fertilization on decomposition of crop residues and their incorporation into microbial communities of 6-year stored soils - Zengqiang Li; Mei Song; Dandan Li; Lei Ma; Bingzi Zhao; Jiabao Zhang (Biology and Fertility of Soils, 2020)

Cytological, genetic, and proteomic analysis of a sesame (Sesamum indicum L.) mutant Siyl-1 with yellow–green leaf color - Tong-Mei Gao; Shuang-Ling Wei; Jing Chen; Yin Wu; Feng Li; Li-Bin Wei; Chun Li; Yan-Juan Zeng; Yuan Tian; Dong-Yong Wang; Hai-Yang Zhang (Genes & Genomics, 2020)
Background Both photosynthetic pigments and chloroplasts in plant leaf cells play an important role in deciding on the photosynthetic capacity and efficiency in plants. Systematical investigating the regulatory mechanism of chloroplast development and chlorophyll (Chl) content variation is necessary for clarifying the photosynthesis mechanism for crops. Objective This study aims to explore the critical regulatory mechanism of leaf color mutation in a yellow–green leaf sesame mutant Siyl - 1 . Methods We performed the genetic analysis of the yellow-green leaf color mutation using the F 2 population of the mutant Siyl - 1 . We compared the morphological structure of the chloroplasts, chlorophyll content of the three genotypes of the mutant F 2 progeny. We performed the two-dimensional gel electrophoresis (2-DE) and compared the protein expression variation between the mutant progeny and the wild type. Results Genetic analysis indicated that there were 3 phenotypes of the F 2 population of the mutant Siyl - 1 , i.e., YY type with light-yellow leaf color (lethal); Yy type with yellow-green leaf color, and yy type with normal green leaf color. The yellow-green mutation was controlled by an incompletely dominant nuclear gene, Siyl - 1 . Compared with the wild genotype, the chloroplast number and the morphological structure in YY and Yy mutant lines varied evidently. The chlorophyll content also significantly decreased ( P < 0.05 ). The 2-DE comparison showed that there were 98 differentially expressed proteins (DEPs) among YY, Yy, and yy lines. All the 98 DEPs were classified into 5 functional groups. Of which 82.7% DEPs proteins belonged to the photosynthesis and energy metabolism group. Conclusion The results revealed the genetic character of yellow-green leaf color mutant Siyl - 1 . 98 DEPs were found in YY and Yy mutant compared with the wild genotype. The regulation pathway related with the yellow leaf trait mutation in sesame was analyzed for the first time. The findings supplied the basic theoretical and gene basis for leaf color and chloroplast development mechanism in sesame.

Risks of maternal prepregnancy overweight/obesity, excessive gestational weight gain, and bottle-feeding in infancy rapid weight gain: evidence from a cohort study in China - Shaoping Yang; Hong Mei; Hui Mei; Yan Yang; Na Li; Yafei Tan; Yiming Zhang; Dan Zhang; Yan Zhang; An’na Peng; Bin Zhang (Science China Life Sciences, 2019)

Enhancement of growth and salt tolerance of tomato seedlings by a natural halotolerant actinobacterium Glutamicibacter halophytocola KLBMP 5180 isolated from a coastal halophyte - You-Wei Xiong; Yuan Gong; Xue-Wei Li; Pan Chen; Xiu-Yun Ju; Chun-Mei Zhang; Bo Yuan; Zuo-Peng Lv; Ke Xing; Sheng Qin (Plant and Soil, 2019)

The efflux pump inhibitor tetrandrine exhibits synergism with fluconazole or voriconazole against Candida parapsilosis - Ya-Jing Zhao; Wei-Da Liu; Yong-Nian Shen; Dong-Mei Li; Kun-Ju Zhu; Hong Zhang (Molecular Biology Reports, 2019)

Bioinformatic prediction of critical genes and pathways involved in longevity in Drosophila melanogaster - Jia-qi Li; Dan-dan Duan; Jian-qin Zhang; Yu-zhi Zhou; Xue-mei Qin; Guan-hua Du; Li Gao (Molecular Genetics and Genomics, 2019)

Stress-dependent anisotropy index of strength and deformability of jointed rock mass: insights from a numerical study - Na Wu; Zheng-zhao Liang; Ying-chun Li; Hong Li; Wan-run Li; Mei-li Zhang (Bulletin of Engineering Geology and the Environment, 2019)

Degradation of 3-fluoroanilne by Rhizobium sp. JF-3 - Zhi-Qing Zhao; Tu-Cai Zheng; Wen-Jing Zhang; Xiao-Li Shen; Liang Lv; Yan-Mei Li (Biodegradation, 2019)

Chachezhania antarctica gen. nov., sp. nov., a novel member of the family ‘Rhodobacteraceae’ isolated from Antarctic seawater - Xiao-xue Yuan; Ning Wang; Meng-yao Zhang; Xiu-lan Chen; Chun-yang Li; Yu-zhong Zhang; Mei Shi; Xi-ying Zhang (Antonie van Leeuwenhoek, 2019)

Rapid diversification of alpine bamboos associated with the uplift of the Hengduan Mountains - Xia‐Ying Ye; Peng‐Fei Ma; Guo‐Qian Yang; Cen Guo; Yu‐Xiao Zhang; Yun‐Mei Chen; Zhen‐Hua Guo; De‐Zhu Li (Journal of Biogeography, 2019)
Aim The Hengduan Mountains (HDM) of southwest China is a biodiversity hotspot and harbours one of the world's richest temperate floras. However, the origin and evolution of its biota remain largely unresolved. Here we explore the impact of mountain uplift on the diversification process of biodiversity in this hotspot using alpine bamboos. Location The HDM region, southwest China. Taxon Alpine bamboos. Methods We used ddRAD‐seq data from the most complete sampling of alpine bamboos undertaken to date (79% of the species diversity), to investigate their evolutionary history. The ancestral area of these bamboos was reconstructed using a time‐calibrated phylogeny in BioGeoBEARS and diversification rates were inferred using BAMM analyses. In addition, the impact of mountain uplift on the divergence of alpine bamboos was evaluated using trait‐dependent models of diversification. Results The alpine bamboos were strongly supported as monophyletic, and the relationships within them were robustly resolved. Fargesia was found to be polyphyletic and Yushania was resolved as monophyletic. Alpine bamboos originated outside the HDM region during the late Miocene, and spread to this region in the Pliocene, undergoing a significant acceleration in net diversification, which is temporally congruent with the orogeny. The speciation rate increased with altitude and a high diversification rate, estimated to be 0.75 species per million years, was detected for alpine bamboos distributed in high elevations. Main Conclusions Our study demonstrates that heterogeneous mountain habitats and geographical isolation of alpine bamboos, which have limited dispersal ability, are important drivers for their rapid diversification. This study also highlights the power of complementary analyses in revealing the link between species diversification and past geological changes.

The Verticillium dahliae Sho1‐MAPK pathway regulates melanin biosynthesis and is required for cotton infection - Jun‐Jiao Li; Lei Zhou; Chun‐Mei Yin; Dan‐Dan Zhang; Steven J. Klosterman; Bao‐Li Wang; Jian Song; Dan Wang; Xiao‐Ping Hu; Krishna V. Subbarao; Jie‐Yin Chen; Xiao‐Feng Dai (Environmental Microbiology, 2019)
Summary Verticillium dahliae is a soil‐borne fungus that causes vascular wilt on numerous plants worldwide. The fungus survives in the soil for up to 14 years by producing melanized microsclerotia. The protective function of melanin in abiotic stresses is well documented. Here, we found that the V . dahliae tetraspan transmembrane protein VdSho1, a homolog of the Saccharomyces cerevisiae Sho1, acts as an osmosensor, and is required for plant penetration and melanin biosynthesis. The deletion mutant Δ Sho1 was incubated on a cellophane membrane substrate that mimics the plant epidermis, revealing that the penetration of Δ Sho1 strain was reduced compared to the wild‐type strain. Furthermore, VdSho1 regulates melanin biosynthesis by a signalling mechanism requiring a kinase‐kinase signalling module of Vst50‐Vst11‐Vst7. Strains, Δ Vst50 , Δ Vst7 and Δ Vst11 also displayed defective penetration and melanin production like the Δ Sho1 strain. Defects in penetration and melanin production in Δ Sho1 were restored by overexpression of Vst50 , suggesting that Vst50 lies downstream of VdSho1 in the regulatory pathway governing penetration and melanin biosynthesis. Data analyses revealed that the transmembrane portion of VdSho1 was essential for both membrane penetration and melanin production. This study demonstrates that Vst50‐Vst11‐Vst7 module regulates VdSho1‐mediated plant penetration and melanin production in V . dahliae , contributing to virulence.

Combined gastroscopic and choledochoscopic transabdominal nasobiliary drainage - Song-mei Lou; Min Zhang; Zheng-rong Wu; Gui-xing Jiang; Hua Shen; Yi Dai; Yue-long Liang; Li-ping Cao; Guo-ping Ding (Journal of Zhejiang University-SCIENCE B, 2019)

Study on dynamic adsorption of p-nitrophenol by multi-walled carbon nanotubes dispersed cyclodextrin - Lizhu Zhang; Wei Tan; Zhenjuan Duan; Mei Bai; Qiuliang Li; Zhibiao Zhao; Min Yang; Hongbin Wang (Environmental Science and Pollution Research, 2019)

Study on main Frequency precursor characteristics of Acoustic Emission from Deep buried Dali Rock explosion - Fuding Mei; Chuanyu Hu; Panyu Li; Junsi Zhang (Arabian Journal of Geosciences, 2019)

Flavivirga rizhaonensis sp. nov., a marine bacterium isolated from intertidal sand - Ang Liu; Hong-Mei Liu; Feng Du; Shuang Wang; Long-Yu Zhao; Hong-Hua Zhang; Yun-Qing Li; Qing-Jie Xue; Xiu-Zhen Li (Antonie van Leeuwenhoek, 2019)

In situ meta‐omic insights into the community compositions and ecological roles of hadal microbes in the Mariana Trench - Zhao‐Ming Gao; Jiao‐Mei Huang; Guo‐Jie Cui; Wen‐Li Li; Jun Li; Zhan‐Fei Wei; Jun Chen; Yong‐Zhi Xin; Du‐Si Cai; Ai‐Qun Zhang; Yong Wang (Environmental Microbiology, 2019)
Summary The low temperature and elevated hydrostatic pressure in hadal trenches at water depths below 6000 m render sample collection difficult. Here, in situ hadal water microbial samples were collected from the Mariana Trench and analysed. The hadal microbial communities at different depths were revealed to be consistent and were dominated by heterotrophic Marinimicrobia. Thirty high‐quality metagenome‐assembled genomes (MAGs) were retrieved to represent the major hadal microbes affiliated with 12 prokaryotic phyla. Most of the MAGs were newly reported and probably derived from novel hadal inhabitants as exemplified by a potentially new candidate archaeal phylum in the DPANN superphylum. Metabolic reconstruction indicated that a great number of the MAGs participated in nitrogen and sulfur cycling, in which the nitrification process was driven sequentially by Thaumarchaeota and Nitrospirae and sulfur oxidization by Rhodospirillales in the Alphaproteobacteria class. Moreover, several groups of hadal microbes were revealed to be potential carbon monoxide oxidizers. Metatranscriptomic result highlighted the contribution of Chloroflexi in degrading recalcitrant dissolved organic matter and Marinimicrobia in extracellular protein decomposition. The present work provides an in‐depth view on the hadal microbial communities regarding their endemism and element cycles.

The metabolic regulation of dietary L‐carnitine in aquaculture nutrition: present status and future research strategies - Ling‐Yu Li; Samwel M. Limbu; Qiang Ma; Li‐Qiao Chen; Mei‐Ling Zhang; Zhen‐Yu Du (Reviews in Aquaculture, 2019)
L‐carnitine is a multi‐functional nutrient which plays a leading role in fatty acid metabolism in mammals and other eukaryotes. Its main physiological function is to promote fatty acid β‐oxidation to produce energy, which reduces body fat content and improves body weight without affecting moisture content in whole body and muscle. In recent years, its dietary supplementation in aquaculture nutrition has been studied in different cultured species. It has been proved that L‐carnitine can improve growth and increase lipid utilization rate in some aquatic animals. However, such beneficial effects of dietary L‐carnitine are limited or absent in other species. The reasons for the conflicting results obtained on L‐carnitine functions in aquatic animals need to be elucidated. This review explores comprehensively the different physiological functions of L‐carnitine in various aquatic animals. In the end, research strategies are provided to elucidate the existing conflicts on dietary L‐carnitine application in aquaculture nutrition in order to promote its utilization in aquatic feed industry.

Three new labdane-type diterpenoids from Callicarpa macrophylla Vahl. - Zhen-Hui Wang; Huan-Jun Xu; Yang-Yang Zhai; Lan-Ping Yang; Qiang Li; Mei Huang; Xing-Ying Chen; Wen-Kui Zhang; Yue-Li Meng; Qing-Ling Zhang; Chao Niu; Yan-Ru Zhang (Natural Product Research, 2019)

A new abietane diterpenoid glycoside from ajuga ovalifolia var. calantha - Fan Yang; Hong-Ping Chen; Xiao-Fei Shen; Hu-Lan Chen; Yin Chen; Li-Xia Wang; Hai Zhang; Wen-Ji Zhao; Mei Zhang; Yu-Zhu Tan (Natural Product Research, 2019)

Genetic Association Between NGFR, ADAM17 Gene Polymorphism, and Parkinson’s Disease in the Chinese Han Population - Wei-Wei Li; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Qian-Qian Shi; Jing Mei; Heng Yang; Fa-Ying Zhou; An-Yu Shi; Tao Zhang; Xiu-Qing Yao; Zhi-Qiang Xu; et al. (Neurotoxicity Research, 2019)

Carbon Monoxide Attenuates High Salt-Induced Hypertension While Reducing Pro-inflammatory Cytokines and Oxidative Stress in the Paraventricular Nucleus - Dong-Dong Zhang; Yan-Feng Liang; Jie Qi; Kai B. Kang; Xiao-Jing Yu; Hong-Li Gao; Kai-Li Liu; Yan-Mei Chen; Xiao-Lian Shi; Guo-Rui Xin; Li-Yan Fu; Yu-Ming Kang; et al. (Cardiovascular Toxicology, 2019)

Isolation and characterization of a novel strain (YH01) of Micropterus salmoides rhabdovirus and expression of its glycoprotein by the baculovirus expression system - Sun-jian Lyu; Xue-mei Yuan; Hai-qi Zhang; Wei-da Shi; Xiao-ying Hang; Li Liu; Ying-lei Wu (Journal of Zhejiang University-SCIENCE B, 2019)

The complete chloroplast genome of Taiwania cryptomerioides (Cupressales: Cupressaceae), an endangered relict conifer species endemic to East Asia - Ling-Li Wang; Yong-Liang Shi; Qi-Lin Zhang; Yan-Ru Guo; Hong-Mei Teng (Conservation Genetics Resources, 2019)

A novel astrovirus identified in wild rhesus monkey feces in China - Yun-yun Xin; Li-li Li; Yuan-yun Ao; Zhi-ping Xie; Jin-song Li; Zhao-jun Duan; Jie-mei Yu; Bing Zhang (Archives of Virology, 2019)

RETRACTED ARTICLE: Cancer-derived exosomal miR-221-3p promotes angiogenesis by targeting THBS2 in cervical squamous cell carcinoma - Xiang-Guang Wu; Chen-Fei Zhou; Yan-Mei Zhang; Rui-Ming Yan; Wen-Fei Wei; Xiao-Jing Chen; Hong-Yan Yi; Luo-Jiao Liang; Liang-sheng Fan; Li Liang; Sha Wu; Wei Wang (Angiogenesis, 2019)

Synthesis of oleanolic acid/ursolic acid/glycyrrhetinic acid-hydrogen sulfide donor hybrids and their antitumor activity - Li-xin Sheng; Jia-yan Huang; Chun-mei Liu; Ju-zheng Zhang; Ke-guang Cheng (Medicinal Chemistry Research, 2019)

Half-dose ticagrelor versus high-dose clopidogrel in reducing platelet reactivity in acute coronary syndrome patients with high on-clopidogrel platelet reactivity (divide study) - Guang Zhong Liu; Song Zhang; Dang Hui Sun; Jing Shi; Wan Lan Bo; Wen Nan Wang; Chong Yang Zhang; Zhong Hua Wang; Wei Feng; Mei Jiao He; Yuan Yuan Liu; Shuang Li; et al. (European Journal of Clinical Pharmacology, 2019)

Knowledge and behavior regarding pesticide use: a survey among caregivers of children aged 1–6 years from rural China - Yuanying Deng; Hongmei Dai; Ming Zeng; Lan Guan; Xiangwen Luo; Chen Zhang; Jing Tian; Jie Zhang; Ying Li; Qiong Xi; Mengwen Zhao; Mei Jiang; et al. (Environmental Science and Pollution Research, 2019)

Biodiversity and antifouling activity of fungi associated with two soft corals from the South China Sea - Xiao-Yong Zhang; Hui-Li Hao; Stanley Chun Kwan Lau; Huai-You Wang; Yu Han; Li-Mei Dong; Ri-Ming Huang (Archives of Microbiology, 2019)

Bacterial community pattern along the sediment seafloor of the Arctic fjorden (Kongsfjorden, Svalbard) - Xiao-Mei Fang; Tao Zhang; Jun Li; Neng-Fei Wang; Zhen Wang; Li-Yan Yu (Antonie van Leeuwenhoek, 2019)

Lignans, flavonoids and coumarins from Viola philippica and their α-glucosidase and HCV protease inhibitory activities - Ya-Li Wang; Lin Zhang; Meng-Yan Li; Li-Wei Wang; Chao-Mei Ma (Natural Product Research, 2019)

Insights from avian influenza surveillance of chickens and ducks before and after exposure to live poultry markets - Mei Li; Xin Yin; Lizheng Guan; Xia Zhang; Guohua Deng; Tao Li; Pengfei Cui; Yong Ma; Yujie Hou; Jianzhong Shi; Hualan Chen (Science China Life Sciences, 2019)

Favus of Scrotum Due to Trichophyton rubrum in Immunocompetent Patients: A Clinical, Mycological and Ultrastructural Study - Ze-Hu Liu; Xiu-Jiao Xia; Yong Zhang; Yan Zhong; Bo Sang; Qiu-Ping Li; Mei Wang; Wen-Wen Lv; Hui-Lin Zhi; Xiang-Dong Wang; Cui-Ping Guan; Hong Shen (Mycopathologia, 2019)

Large Addition of Freshwater to the Tidal Reaches of the Yangtze (Changjiang) River - Xuefei Mei; Min Zhang; Zhijun Dai; Wen Wei; Weihua Li (Estuaries and Coasts, 2019)

Resistance of alfalfa and Indian mustard to Cd and the correlation of plant Cd uptake and soil Cd form - Chunlai Zhang; Yongqin Chen; Weihong Xu; Sunlin Chi; Tao Li; Yanhua Li; Zhangmi He; Mei Yang; Deyu Feng (Environmental Science and Pollution Research, 2019)

Differences of Cd uptake and expression of MT family genes and NRAMP2 in two varieties of ryegrasses - Yanhua Li; Yuli Qin; Weihong Xu; Yourong Chai; Tao Li; Chunlai Zhang; Mei Yang; Zhangmi He; Deyu Feng (Environmental Science and Pollution Research, 2019)

Effects of dietary Allium mongolicum Regel polysaccharide on growth, lipopolysaccharide-induced antioxidant responses and immune responses in Channa argus - Mu-Yang Li; Xin-Ming Zhu; Xiao-Tian Niu; Xiu-Mei Chen; Jia-Xin Tian; Yi-Di Kong; Dong-Ming Zhang; Lei Zhao; Gui-Qin Wang (Molecular Biology Reports, 2019)

Complete nucleotide sequence of a novel mycovirus from Trichoderma harzianum in China - Chenchen Liu; Mei Li; Estifanos Tsegaye Redda; Jie Mei; Jiantai Zhang; Santiago F. Elena; Beilei Wu; Xiliang Jiang (Archives of Virology, 2019)

Expression of the intrarenal angiotensin receptor and the role of renin-angiotensin system inhibitors in IgA nephropathy - Zheng Zhang; Shi-min Jiang; Ye-ping Ma; Pei-lin Dai; Yi-ning Wang; Gu-ming Zou; Hong-mei Gao; Yue Yang; Wen-ge Li (Molecular and Cellular Biochemistry, 2019)

Simultaneous prediction of rock matrix modulus and critical porosity - Nuo Li; Hao Chen; Xiu-Mei Zhang; Jian-Qiang Han; Jian Wang; Xiu-Ming Wang (Applied Geophysics, 2019)

Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides - Qing-Yan Tang; Geng Chen; Wan-Ling Song; Wei Fan; Kun-Hua Wei; Si-Mei He; Guang-Hui Zhang; Jun-Rong Tang; Ying Li; Yuan Lin; Sheng-Chao Yang (Planta, 2019)

L-3-n-butylphthalide attenuates cognitive deficits in db/db diabetic mice - Song-yun Zhang; Su-xiao Ji; Xiao-mei Bai; Fang Yuan; Li-hui Zhang; Jie Li (Metabolic Brain Disease, 2019)

Luminescence chronology of the Palaeolithic–Neolithic transition in the Yujiagou site at the Nihewan Basin, northern China - Xue Rui; Yu‐Jie Guo; Jia‐Fu Zhang; Yue Hu; Hui‐Jie Mei; You‐Ping Wang; Fei Xie; Bo Li (Journal of Quaternary Science, 2019)
The relationship between the Palaeolithic–Neolithic cultural transition and environmental changes is important for understanding human history. However, the timing and nature of human behaviour at the transition, and their relationship to local environmental conditions, remain poorly understood. The Yujiagou archaeological site in the Nihewan Basin, northern China, provides valuable chronological and archaeological information about cultural changes in northern China due to its continuous archaeological sequence of cultural layers from the Palaeolithic to Neolithic. In this study, we apply post‐infrared infrared stimulated luminescence (pIRIR) dating on individual feldspar grains to date the Yujiagou deposits. We provide a revised chronology for the archaeological sequence at the site. We combine these results with multi‐proxy climatic indicators to gain insights into palaeoenvironmental changes in the region. The results show that the age of the artefact‐bearing deposits ranges from 13.5 to 9.7 ka. Polished stones and pottery begin to occur in the archaeological layer around 13 ka, corresponding to a transitional period when the local climate changed from cold to warm. This site provides evidence for understanding the process that led to the regional transition from hunter‐gathering to farming.

Genomics insights into ecotype formation of ammonia‐oxidizing archaea in the deep ocean - Yong Wang; Jiao‐Mei Huang; Guo‐Jie Cui; Takuro Nunoura; Yoshihiro Takaki; Wen‐Li Li; Jun Li; Zhao‐Ming Gao; Ken Takai; Ai‐Qun Zhang; Ramunas Stepanauskas (Environmental Microbiology, 2019)
Summary Various lineages of ammonia‐oxidizing archaea (AOA) are present in deep waters, but the mechanisms that determine ecotype formation are obscure. We studied 18 high‐quality genomes of the marine group I AOA lineages (alpha, gamma and delta) from the Mariana and Ogasawara trenches. The genomes of alpha AOA resembled each other, while those of gamma and delta lineages were more divergent and had even undergone insertion of some phage genes. The instability of the gamma and delta AOA genomes could be partially due to the loss of DNA polymerase B ( polB) and methyladenine DNA glycosylase ( tag ) genes responsible for the repair of point mutations. The alpha AOA genomes harbour genes encoding a thrombospondin‐like outer membrane structure that probably serves as a barrier to gene flow. Moreover, the gamma and alpha AOA lineages rely on vitamin B 12 ‐independent MetE and B 12 ‐dependent MetH, respectively, for methionine synthesis. The delta AOA genome contains genes involved in uptake of sugar and peptide perhaps for heterotrophic lifestyle. Our study provides insights into co‐occurrence of cladogenesis and anagenesis in the formation of AOA ecotypes that perform differently in nitrogen and carbon cycling in dark oceans.

Viral metagenomics analysis and eight novel viral genomes identified from the Dushanzi mud volcanic soil in Xinjiang, China - Dan-Ting Yu; Ji-Zheng He; Li-Mei Zhang; Li-Li Han (Journal of Soils and Sediments, 2019)

Distributions and environmental drivers of archaea and bacteria in paddy soils - Chao-Lei Yuan; Li-Mei Zhang; Jun-Tao Wang; Hang-Wei Hu; Ju-Pei Shen; Peng Cao; Ji-Zheng He (Journal of Soils and Sediments, 2019)

Effects of tetrabromobisphenol A on maize (Zea mays L.) physiological indexes, soil enzyme activity, and soil microbial biomass - Ying Wang; Mei Zhang; Lifang Zhao; Wei Zhang; Ting Zhao; Jingxuan Chu; Yanhao Qiu; Hangyuan Gong; Ruijin Li (Ecotoxicology, 2019)

Identification of QTL regions for seedling root traits and their effect on nitrogen use efficiency in wheat (Triticum aestivum L.) - Xiaoli Fan; Wei Zhang; Na Zhang; Mei Chen; Shusong Zheng; Chunhua Zhao; Jie Han; Jiajia Liu; Xilan Zhang; Liqiang Song; Jun Ji; Xigang Liu; et al. (Theoretical and Applied Genetics, 2018)

miR-377-3p regulates adipogenic differentiation of human bone marrow mesenchymal stem cells by regulating LIFR - Xingnuan Li; Yaofang Yang; Ruiqiao Yan; Xiaoyuan Xu; Liyun Gao; Jun Mei; Jianyun Liu; Xinping Wang; Jie Zhang; Ping Wu; Weidong Li; Zhijun Zhao; et al. (Molecular and Cellular Biochemistry, 2018)

Genetic characterization and fine mapping for multi-inflorescence in Brassica napus L. - Yongjing Zhang; Qinfei Li; Yixin Cui; Zhi Liu; Zhifu Chen; Yajun He; Jiaqin Mei; Qing Xiong; Xiaorong Li; Wei Qian (Theoretical and Applied Genetics, 2018)

KH-type splicing regulatory protein is regulated by nuclear factor-κB signaling to mediate innate immunity in Caco-2 cells infected by Salmonella enteritidis - Yuanyang Nie; Mei Cao; Daoyan Wu; Ningzhe Li; Jingshan Peng; Sijun Yi; Xiaofan Yang; Mao Zhang; Guoku Hu; Jian Zhao (Folia Microbiologica, 2018)

Uptake of Urea Nitrogen by Oocystis borgei in Prawn (Litopenaeus vannamei) Aquaculture Ponds - Mei Liu; Xianghu Huang; Rui Zhang; Changling Li; Binhe Gu (Bulletin of Environmental Contamination and Toxicology, 2018)

Novel Self-Assembled Ibrutinib-Phospholipid Complex for Potently Peroral Delivery of Poorly Soluble Drugs with pH-Dependent Solubility - Qiujun Qiu; Mei Lu; Cong Li; Xiang Luo; Xinrong Liu; Ling Hu; Mingqi Liu; Huangliang Zheng; Hongxia Zhang; Min Liu; Chaoyang Lai; Yanzhi Song; et al. (AAPS PharmSciTech, 2018)

Associations of HSP90AA2 gene polymorphisms with disease susceptibility, glucocorticoids efficacy and health-related quality of life in Chinese systemic lupus erythematosus patients - Man Zhang; Su-Su Li; Qiao-Mei Xie; Jian-Hua Xu; Xiu-Xiu Sun; Fa-Ming Pan; Sheng-Qian Xu; Sheng-Xiu Liu; Jin-Hui Tao; Shuang Liu; Jing Cai; Pei-Ling Chen; et al. (Genes & Genomics, 2018)

Anxiolytic potency of iridoid fraction extracted from Valeriana jatamansi Jones and its mechanism: a preliminary study - Xue-Mei Zhang; Jia-Li Zhu; Yong Sun; Yao-Lan Dai; Xiu Chen; Jia-Hong Cao; Ruo-Cong Yang; Chang Chen; Chao-Ying Ma; Tian-E Zhang; Yun-Hui Chen; Zhi-Yong Yan (Natural Product Research, 2018)

Engineering herbicide-resistant watermelon variety through CRISPR/Cas9-mediated base-editing - Shouwei Tian; Linjian Jiang; Xiaxia Cui; Jie Zhang; Shaogui Guo; Maoying Li; Haiying Zhang; Yi Ren; Guoyi Gong; Mei Zong; Fan Liu; Qijun Chen; et al. (Plant Cell Reports, 2018)

Chromosome-wide gene dosage rebalance may benefit tumor progression - Honglei Zhang; Xing Yang; Xu Feng; Haibo Xu; Qin Yang; Li Zou; Mei Yan; Dequan Liu; Xiaosan Su; Baowei Jiao (Molecular Genetics and Genomics, 2018)

Intermittent micro-aeration control of methane emissions from an integrated vertical-flow constructed wetland during agricultural domestic wastewater treatment - Xiaoling Liu; Ke Zhang; Liangqian Fan; Hongbing Luo; Mingshu Jiang; Bruce C. Anderson; Mei Li; Bo Huang; Lijuan Yu; Guozhu He; Jingting Wang; Aiping Pu (Environmental Science and Pollution Research, 2018)

A New Approach of Rpf Addition to Explore Bacterial Consortium for Enhanced Phenol Degradation Under High Salinity Conditions - Ziqiao Li; Yunge Zhang; Yuyang Wang; Rongwu Mei; Yu Zhang; Muhammad Zaffar Hashmi; Hongjun Lin; Xiaomei Su (Current Microbiology, 2018)

Community and functional shifts in ammonia oxidizers across terrestrial and marine (soil/sediment) boundaries in two coastal Bay ecosystems - Li‐Mei Zhang; Aoife M. Duff; Cindy J. Smith (Environmental Microbiology, 2018)
Summary Terrestrial–marine boundaries are significant sites of biogeochemical activity with delineated gradients from land to sea. While niche differentiation of ammonia‐oxidizing archaea (AOA) and bacteria (AOB) driven by pH and nitrogen is well known, the patterns and environmental drivers of AOA and AOB community structure and activity across soil‐sediment boundaries have not yet been determined. In this study, nitrification potential rate, community composition and transcriptional activity of AOA and AOB in soil, soil/sediment interface and sediments of two coastal Bays were characterized using a combination of field investigations and microcosm incubations. At DNA level, amoA gene abundances of AOA were significantly greater than AOB in soil, while in sediments AOB were significantly more abundant than AOA, but at the soil/sediment interface there were equal numbers of AOA and AOB amoA genes. Microcosm incubations provided further evidence, through qPCR and DGGE‐sequencing analysis of amoA transcripts, that AOA were active in soil, AOB in sediment and both AOA and AOB were active at the soil/sediment interface. The AOA and AOB community composition shifted across the coastal soil‐interface‐sediment gradient with salinity and pH identified as major environmental drivers.

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress - Qiao Huang; Meiling Sun; Mei Li; Dingmei Zhang; Feng Han; Jun Chao Wu; Kohji Fukunaga; Zhong Chen; Zheng-Hong Qin (Molecular Neurobiology, 2018)

Variable hydrological effects of herbs and shrubs in the arid northeastern Qinghai-Tibet Plateau, China - Ya-bin Liu; Ying Zhang; Jiang-tao Fu; Dong-mei Yu; Xia-song Hu; Xi-lai Li; Zhao-xin Qi; Shu-xia Li (Journal of Mountain Science, 2018)

Focusing quorum sensing signalling by nano‐magnetic assembly - Yongguang Guan; Chen‐Yu Tsao; David N. Quan; Ying Li; Lei Mei; Yingying Song; Boce Zhang; Yi Liu; Gregory F. Payne; William E. Bentley; Qin Wang (Environmental Microbiology, 2018)
Summary Quorum sensing (QS) exists widely among bacteria, enabling a transition to multicellular behaviour after bacterial populations reach a particular density. The coordination of multicellularity enables biotechnological application, dissolution of biofilms, coordination of virulence, and so forth. Here, a method to elicit and subsequently disperse multicellular behaviour among QS‐negative cells is developed using magnetic nanoparticle assembly. We fabricated magnetic nanoparticles (MNPs, ∼5 nm) that electrostatically collect wild‐type (WT) Escherichia coli BL21 cells and brings them into proximity of bioengineered E. coli [CT104 (W3110 lsrFG − luxS − pCT6 + pET‐DsRed)] reporter cells that exhibit a QS response after receiving autoinducer‐2 (AI‐2). By shortening the distance between WT and reporter cells (e.g., increasing local available AI‐2 concentrations), the QS response signalling was amplified four‐fold compared to that in native conditions without assembly. This study suggests potential applications in facilitating intercellular communication and modulating multicellular behaviours based on user‐specified designs.

An integrated assessment of INDCs under Shared Socioeconomic Pathways: an implementation of C3IAM - Yi-Ming Wei; Rong Han; Qiao-Mei Liang; Bi-Ying Yu; Yun-Fei Yao; Mei-Mei Xue; Kun Zhang; Li-Jing Liu; Juan Peng; Pu Yang; Zhi-Fu Mi; Yun-Fei Du; et al. (Natural Hazards, 2018)

Repressible Transgenic Sterilization in Channel Catfish, Ictalurus punctatus, by Knockdown of Primordial Germ Cell Genes with Copper-Sensitive Constructs - Hanbo Li; Baofeng Su; Guyu Qin; Zhi Ye; Ahmed Elaswad; Ahmed Alsaqufi; Dayan A. Perera; Zhenkui Qin; Ramji Odin; Khoi Vo; David Drescher; Dalton Robinson; et al. (Marine Biotechnology, 2018)

Experimental infection of Marmota monax with a novel hepatitis A virus - Jie-mei Yu; Li-li Li; Guang-cheng Xie; Cui-yuan Zhang; Yuan-yun Ao; Zhao-jun Duan (Archives of Virology, 2018)

Responses of soil microbial community to nitrogen fertilizer and precipitation regimes in a semi-arid steppe - Yi-Fei Sun; Ju-Pei Shen; Cui-Jing Zhang; Li-Mei Zhang; Wen-Ming Bai; Ying Fang; Ji-Zheng He (Journal of Soils and Sediments, 2018)

Safety, pharmacokinetics, and pharmacodynamics of S-(−)-pantoprazole sodium injections after single and multiple intravenous doses in healthy Chinese subjects - Hui-Wen Jiao; Lu-Ning Sun; Yue-Qi Li; Lei Yu; Hong-Wen Zhang; Mei-Feng Wang; Li-Yuan Yu; Zi-Qing-Yun Yuan; Li-Jun Xie; Juan Chen; Ling Meng; Xue-Hui Zhang; et al. (European Journal of Clinical Pharmacology, 2018)

Use of freeze-dried bone allografts in osteoporotic patients undergoing median sternotomy - Mei Liang; Jianzhou Liu; Qi Miao; Guotao Ma; Xingrong Liu; Xiaofeng Li; Chaoji Zhang (Cell and Tissue Banking, 2018)

Comparative WGBS identifies genes that influence non-ripe phenotype in tomato epimutant Colourless non-ripening - Weiwei Chen; Zhiming Yu; Junhua Kong; Hui Wang; Yichen Li; Mei Zhao; Xiaohong Wang; Qianqian Zheng; Nongnong Shi; Pengcheng Zhang; Silin Zhong; Paul Hunter; et al. (Science China Life Sciences, 2018)

Optimization of culture conditions for the production of polysaccharides and kinsenoside from the rhizome cultures of Anoectochilus roxburghii (Wall.) Lindl. - Mei Yu Jin; Li Qiu Zhang; Xuan Chun Piao; Ri Gao; Mei Lan Lian (In Vitro Cellular & Developmental Biology - Plant, 2018)

Knockdown of PRMT1 suppresses IL-1β-induced cartilage degradation and inflammatory responses in human chondrocytes through Gli1-mediated Hedgehog signaling pathway - Lei Xia; Hong-Xing Zhang; Mei-Li Xing; Yu-Ben Xu; Peng Li; Liang-Ku Huang; Jie Bai; Zhao Tian; Zan-Dong Zhao (Molecular and Cellular Biochemistry, 2018)

Vimentin is a crucial target for anti-metastasis therapy of nasopharyngeal carcinoma - Wei Wang; Mei Yi; Renya Zhang; Junjun Li; Shengnan Chen; Jing Cai; Zhaoyang Zeng; Xiaoling Li; Wei Xiong; Li Wang; Guiyuan Li; Bo Xiang (Molecular and Cellular Biochemistry, 2018)

Complementary feeding patterns among ethnic groups in rural western China - Peng-fei Qu; Ya Zhang; Jia-mei Li; Ruo Zhang; Jiao-mei Yang; Fang-liang Lei; Shan-shan Li; Dan-meng Liu; Shao-nong Dang; Hong Yan (Journal of Zhejiang University-SCIENCE B, 2018)

C21 steroid derivatives from the Dai herbal medicine Dai-Bai-Jie, the dried roots of Marsdenia tenacissima, and their screening for anti-HIV activity - Xu Pang; Li-Ping Kang; Xiao-Mei Fang; He-Shui Yu; Li-Feng Han; Yang Zhao; Li-Xia Zhang; Li-Yan Yu; Bai-Ping Ma (Journal of Natural Medicines, 2018)

Enhanced stabilization of Pb, Zn, and Cd in contaminated soils using oxalic acid-activated phosphate rocks - Zhuo Zhang; Guanlin Guo; Mei Wang; Jia Zhang; Zhixin Wang; Fasheng Li; Honghan Chen (Environmental Science and Pollution Research, 2018)

Involvement of IL-17 in Secondary Brain Injury After a Traumatic Brain Injury in Rats - Tan Li; Yong-mei Zhang; Dong Han; Rong Hua; Bing-nan Guo; Shu-qun Hu; Xian-liang Yan; Tie Xu (NeuroMolecular Medicine, 2017)

Down-regulation of Noggin and miR-138 coordinately promote osteogenesis of mesenchymal stem cells - Xing-Kun Sun; Jin Zhou; Lei Zhang; Tian Ma; Yu-Han Wang; Yan-Mei Yang; Yan-Ting Tang; Hong Li; Li-Jun Wang (Journal of Molecular Histology, 2017)