3D Seismic Stability Analysis of Bench Slope with Pile Reinforcement - Sheng-yu Yang; Zhen Wang; Jia-man Wang; Ming-wei Gong; Jian-fei Li; Zhi-bin Sun (Geotechnical and Geological Engineering, 2022)

Reliability Analysis of Reinforced Slope Combining Random Forest Algorithm and Meshless SPH Algorithm - Xu Liu; Liang Li; ShangShang Wang; Fu Chen; Ming Zhai; Zhengquan Yang; Yuan Gao (Geotechnical and Geological Engineering, 2022)

Study on the impact of comprehensive urbanization on urban civil building CO2 emissions in China - Rong Guo; Nan Li; Hailin Mu; Ming Zhang; Xiyue Yang; Yixuan Han; Rongkang Yao; Zhihao Shao (Environmental Science and Pollution Research, 2022)

The Q225P Mutation in SigB Promotes Membrane Vesicle Formation in Staphylococcus aureus - Li Qiao; Yi Yang; Keting Zhu; Yifan Rao; Gang Li; Xiancai Rao; Ming Li; Renjie Zhou (Current Microbiology, 2022)

The antioxidant activities of flavonoids in Jerusalem artichoke ( Helianthus tuberosus L.) leaves and their quantitative analysis - Ming-Yang Wang; Zhi-Li Ma; Cheng-Li He; Xiao-Yan Yuan (Natural Product Research, 2022)

Selenium Attenuates S. aureus-Induced Inflammation by Regulation TLR2 Signaling Pathway and NLRP3 Inflammasome in RAW 264.7 Macrophages - Ming-Ji Wei; Zhen-Nan Wang; Yan Yang; Shu-Jiu Zhang; He Tang; Hui Li; Chong-Liang Bi (Biological Trace Element Research, 2022)

Methods for the construction of DEMs of artificial slopes considering morphological features and semantic information - Yan Xu; Ming-wei Zhao; Jie Lu; Chun Wang; Ling Jiang; Can-can Yang; Xiao-li Huang (Journal of Mountain Science, 2022)

Flavobacterium proteolyticum sp. nov., isolated from aquaculture water - Juan Du; Yang Liu; Tao Pei; Anzhang Li; Ming-Rong Deng; Honghui Zhu (Archives of Microbiology, 2022)

A feasible vibration measurement and active control method of reinforced concrete lightweight pier railway bridges for heavy-haul monorail trains - Ling-kun Chen; Li-zhong Jiang; Rui Li; Qiao Li; Ming Zhang; Nan Zhang; Jin-zhang Luo; Liang Ling; Sheng-yang Zhu (European Journal of Environmental and Civil Engineering, 2022)

Integrins in the Regulation of Mesenchymal Stem Cell Differentiation by Mechanical Signals - Lei Wang; Fuwen Zheng; Ruixue Song; Lequan Zhuang; Ming Yang; Jian Suo; Lisha Li (Stem Cell Reviews and Reports, 2022)

Bivalent Regulation and Related Mechanisms of H3K4/27/9me3 in Stem Cells - Han Sun; Yin Wang; Ying Wang; Feng Ji; An Wang; Ming Yang; Xu He; Lisha Li (Stem Cell Reviews and Reports, 2022)

Scalp Acupuncture Protects Against Neuronal Ferroptosis by Activating The p62-Keap1-Nrf2 Pathway in Rat Models of Intracranial Haemorrhage - Ming-Yue Li; Xiao-Hong Dai; Xue-Ping Yu; Wei Zou; Wei Teng; Peng Liu; Xin-Yang Yu; Qi An; Xin Wen (Journal of Molecular Neuroscience, 2022)
Intracerebral haemorrhage (ICH) can be a catastrophic event; even if the initial stages of the pathology were well-managed, a number of patients experience varied residual neurological deficits following the insult. Ferroptosis is a recently identified type of cell demise which is tightly linked to the neurological impairment associated with ICH. In the current work, the prophylactic impact of scalp acupuncture (SA) therapy on autologous blood injection murine models of ICH was investigated in order to establish whether SA could mitigate the secondary damage arising following ICH by moderating ferroptosis. The pathophysiological mechanisms associated with this process were also explored. Ludmila Belayev tests were utilised for the characterisation of neurological damage. Haematoxylin–eosin staining was employed in order to determine the cerebral impact of the induced ICH. Malondialdehyde (MDA) and iron titres in peri-haemorrhagic cerebral tissues were appraised using purchased assay kits. Transmission electron microscopy delineated mitochondrial appearances within nerve cell bodies from the area of haemorrhage. Western blotting techniques were utilised to assay the degree of protein expression of NeuN, sequestosome 1 (p62), nuclear factor erythroid 2-related factor 2 (Nrf2), Kelch-like ECH-associated protein 1 (Keap1), glutathione peroxidase 4 (GPX4) and ferritin heavy chain 1 (FTH1). The frequencies of Nrf2, GPX4 and FTH1 positive cells, respectively, were documented with immunohistochemical staining. The results demonstrated that therapy with SA after ICH mitigated MDA and iron sequestration, diminished the appearance of contracted mitochondria with increased outer mitochondrial membrane diameter within the nerve cell bodies, and suppressed neuronal ferroptosis. The pathways responsible for these effects may encompass amplified p62, Nrf2, GPX4 and FTH1 expression, together with decreased Keap1 expression. Application of SA reduced identified neurobehavioural abnormalities after ICH; no disparities were observed between the consequences of SA therapy and deferoxamine delivery. It can be surmised that intervention with SA enhanced recovery after ICH by triggering the antioxidant pathway, p62/Keap1/Nrf2, and causing FTH1 and GPX4 upregulation, factors that participate in diminishing excess iron and thus in mitigating lipid peroxidation insults arising from ferroptosis following ICH.

Analysis of equivalent thickness of geological media for lab-scale study of radon exhalation - Changshou Hong; Yini Yang; Hong Wang; Yong Liu; Xiangyang Li; Bo Lei; Ming Lan; Yifan Chen; Xingwang Dai (Environmental Science and Pollution Research, 2022)

Using Mendelian randomization as the cornerstone for causal inference in epidemiology - Jianguo Xu; Muyang Li; Ya Gao; Ming Liu; Shuzhen Shi; Jiyuan Shi; Kelu Yang; Zheng Zhou; Jinhui Tian (Environmental Science and Pollution Research, 2022)

Williamsia soli sp. nov., an actinobacterium isolated from soil at a thermal power plant in Yantai, China - Ming-Jing Zhang; Xue-Han Li; Li-Yang Peng; Shuai-Ting Yun; Zhuo-Cheng Liu; Yan-Xia Zhou (Archives of Microbiology, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Species Composition and Assemblages of Ichthyoplankton in Sansha Bay, Fujian Province, China - Yan Jiang; Bai-an Lin; Hao-yang He; Guang-mao Ding; Li-ting Yan; Ge Zhang; Min Liu; Lian-ming Zheng (Frontiers in Marine Science, 2021)
Sansha Bay (26.40−27.00°N, 119.50−120.20°E) is a typical semi-enclosed bay, located in northern Fujian Province, China, and adjacent to the East China Sea. The ichthyoplankton species composition and assemblage structure were investigated based on monthly sampling at 25 stations in April−September 2019, covering the important spring and summer spawning seasons in the region. Sampling was conducted in the first 3−5 days of the full moon or new moon phases using a standard plankton net through horizontal and vertical tows during daytime. In total, 25,819 ichthyoplankton samples were collected, of which 25,449 samples (i.e., 24,757 eggs and 692 larvae) were from horizontal tows. For horizontal tow samples, the ichthyoplankton were classified into 58 taxa in 15 orders and 23 families with a combination of external morphology and DNA barcoding analyses, from pelagic to demersal and benthic species. The dominant order was the Gobiiformes, including 23 species (39.7% of all species). The dominant taxa, in terms of relative abundance and frequency of occurrence, consisted of commercially important fishes, such as Setipinna tenuifilis (Valenciennes, 1848) (Engraulidae), Epinephelus akaara (Temminck and Schlegel, 1842) (Serraenidae), Collichthys lucidus (Richardson, 1844), Nibea albiflora (Richardson, 1846) (Sciaenidae), Acanthopagrus schlegelii (Bleeker, 1854), and Pagrus major (Temminck and Schlegel, 1843) (Sparidae), accounting for 78.9% of the horizontal tow samples. Low-valued and small-sized fishes, such as Stolephorus commersonnii Lacepède, 1803 (Engraulidae), Solea ovata Richardson, 1846 (Soleidae), Nuchequula nuchalis (Temminck and Schlegel, 1845), and Photopectoralis bindus (Valenciennes, 1835) (Leiognathidae), were also dominant species, accounting for 11.4% of the horizontal tow samples. The ichthyoplankton assemblage was categorized into five different temporal assemblages based on the cluster and nonmetric multidimensional scaling analysis, namely, April, May, June, July, and August−September (ANOSIM, Global R = 0.656, p < 0.01) with the highest density and richness of ichthyoplankton occurred in May. The spatial distribution pattern showed that the high density (ind./m 3 ) of ichthyoplankton occurred mainly in S12–S25 in Guanjingyang and along the Dongchong Peninsula coastline into Dongwuyang, while low density occurred mainly in S01–S11 in the northwest waters of Sandu Island (ANOVA, F = 8.270, p < 0.05). Temperature, salinity, and chlorophyll a were key factors structuring the ichthyoplankton assemblages in Sansha Bay. In addition, this study revealed the changes of the ichthyoplankton composition, density, and spatial distribution in Sansha Bay over the past three decades.

Ferroptosis inhibitory constituents from the fruits of Cullen corylifolium - Aftab Yaseen; Fan Yang; Xia Zhang; Fu Li; Bin Chen; Ahmed Hassan Ibrahim Faraag; Ming-Kui Wang; Xiao-Fei Shen; Lun Wang (Natural Product Research, 2021)

Groundwater and root trait diversity jointly drive plant fine root biomass across arid inland river basin - Yin Wang; Jian-Ming Wang; Huan Yang; Guan-Jun Li; Chen Chen; Jing-Wen Li (Plant and Soil, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Muricauda chongwuensis sp. nov., isolated from coastal seawater of China - Ming-Xia Chen; Xiao-Yu He; He-Yang Li (Archives of Microbiology, 2021)

Optimization of immunization procedure for SWCNTs‐based subunit vaccine with mannose modification against spring viraemia of carp virus in common carp - Yu‐Ming Gong; Chen Zhang; Yang Li; Guo Chen; Gao‐Xue Wang; Bin Zhu (Journal of Fish Diseases, 2021)
Immersion vaccination of single‐walled carbon nanotubes loaded with mannose‐modified glycoprotein (SWCNTs‐MG) vaccine has been proved to be effective in preventing spring viraemia of carp virus (SVCV). Immunization procedure has immense consequence on the immune effect of the immersion vaccine. However, immunization procedure optimization for SWCNTs‐MG vaccine against SVCV has not been reported. In this study, accordingly, a full‐factor experiment was designed to optimize the immunization procedure of SWCNTs‐MG vaccine by three aspects of vaccine dose (30 mg/L, 40 mg/L and 50 mg/L), immunization density (8 fish L −1 , 24 fish L −1 and 48 fish L −1 ) and immunization time (6, 12 and 24 hr). Furthermore, we used the immunization group (A1B2C1, 30 mg/L, 24 fish L −1 and 6 hr) in the previous study as a positive control (PC) to evaluate the immunization effect optimized conditions from the expression of immune‐related genes and relative percentage survival (RPS). At 28 days post‐vaccination (DPV), common carps were intraperitoneal injected SVCV challenged test indicated that the A1B2C2 group (30 mg/L, 24 fish L −1 , 12 hr) displayed superiority of protective efficacy compare with other groups and the RPS with 77.9%, which was 15.6% higher than the PC group of RPS with 62.3%. Moreover, the expression of immune‐related genes such as IL‐10 , CD4 and MHC‐II was also significantly higher than PC group. The specific experimental flow chart is shown in Figure 1 . Conclusively, these results demonstrated that vaccine dose, immunization density and immunization time are 30 mg/L, 24 fish L −1 and 12 hr, which is the more appropriate immunization programme with juvenile carp for SWCNTs‐MG vaccine. This study provides a profitable reference for improving the immune efficiency of aquatic immersion vaccine. The experiment process and timeline chart of the present research image

Theoretical and Numerical Analysis of Blasting Pressure of Cylindrical Shells under Internal Explosive Loading - Zhan-Feng Chen; Hui-Jie Wang; Zhiqian Sang; Wen Wang; He Yang; Wei-Ming Meng; Yu-Xing Li (Journal of Marine Science and Engineering, 2021)
Cylindrical shells are principal structural elements that are used for many purposes, such as offshore, sub-marine, and airborne structures. The nonlinear mechanics model of internal blast loading was established to predict the dynamic blast pressure of cylindrical shells. However, due to the complexity of the nonlinear mechanical model, the solution process is time-consuming. In this study, the nonlinear mechanics model of internal blast loading is linearized, and the dynamic blast pressure of cylindrical shells is solved. First, a mechanical model of cylindrical shells subjected to internal blast loading is proposed. To simplify the calculation, the internal blast loading is reduced to linearly uniform variations. Second, according to the stress function method, the dynamic blast pressure equation of cylindrical shells subjected to blast loading is derived. Third, the calculated results are compared with those of the finite element method (FEM) under different durations of dynamic pressure pulse. Finally, to reduce the errors, the dynamic blast pressure equation is further optimized. The results demonstrate that the optimized equation is in good agreement with the FEM, and is feasible to linearize the internal blast loading of cylindrical shells.

Identification and antimicrobial properties of a new alkaloid produced by marine-derived Verrucosispora sp. FIM06-0036 - Ming-Hong Chen; Yun-Yang Lian; Dong-Sheng Fang; Li Chen; Jia Jia; Wen-Long Zhang; Ru Lin; Yang Xie; Hong-Kai Bi; Hong Jiang (Natural Product Research, 2021)

FHA domain of AGGF1 is essential for its nucleocytoplasmic transport and angiogenesis - Cui-Fang Zhang; Han-Ming Wang; Andong Wu; Yang Li; Xiao-Li Tian (Science China Life Sciences, 2021)

Exposure to 2,4-dichlorophenol, 2,4,6-trichlorophenol, pentachlorophenol and risk of thyroid cancer: a case-control study in China - Wan-Jun Yang; Hua-Bing Wu; Chi Zhang; Qi Zhong; Ming-Jun Hu; Jia-Liu He; Guo-Ao Li; Zhen-Yu Zhu; Jin-Liang Zhu; Huan-Huan Zhao; Han-Shuang Zhang; Fen Huang (Environmental Science and Pollution Research, 2021)

Carbonic Anhydrase III Attenuates Hypoxia-Induced Apoptosis and Activates PI3K/Akt/mTOR Pathway in H9c2 Cardiomyocyte Cell Line - Hua Li; Yibin Liu; Sha Tang; Jie Hu; Qiuling Wu; Yang Wei; Ming Niu (Cardiovascular Toxicology, 2021)

Effects of organic acids on the chemotaxis profiles and biocontrol traits of antagonistic bacterial endophytes against root-rot disease in Panax notoginseng - Li Ma; Wu-Qin Wang; Rui Shi; Xue-Mei Zhang; Xin Li; Yu-Sen Yang; Ming He Mo (Antonie van Leeuwenhoek, 2021)

Tissue distribution of SARS-CoV-2 in non-human primates after combined intratracheal and intranasal inoculation - Tian-Zhang Song; Jian-Bao Han; Xiang Yang; Ming-Hua Li; Yong-Tang Zheng (Science China Life Sciences, 2021)

Automatic feature extraction and fusion recognition of motor imagery EEG using multilevel multiscale CNN - Ming-ai Li; Jian-fu Han; Jin-fu Yang (Medical & Biological Engineering & Computing, 2021)

Inhibition of Maternal c-Src Ameliorates the Male Offspring Hypertension by Suppressing Inflammation and Neurotransmitters in the Paraventricular Nucleus - Qing Su; Xiao-Jing Yu; Qing Yang; Xiao-Min Wang; Wen-Jie Xia; Hong-Bao Li; Kai-Li Liu; Qiu-Yue Yi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Apportioning above- and below-ground effects of moss biocrusts on soil detachment by overland flow in a subtropical climate - Guan-hua Zhang; Liang Yi; Wen-feng Ding; Xu Lei; Yi-ran Wang; Bao-yang Sun; Jian-ming Li (Journal of Mountain Science, 2021)

A new strategy combined HASM and classical interpolation methods for DEM construction in areas without sufficient terrain data - Jing Wang; Ming-wei Zhao; Ling Jiang; Can-can Yang; Xiao-li Huang; Yan Xu; Jie Lu (Journal of Mountain Science, 2021)

Cross‐phytogroup assessment of foliar epiphytic mycobiomes - Ting Zhu; Jia Yao; Hao Liu; Chen‐Hao Zhou; Yuan‐Zhan Liu; Zheng‐Wei Wang; Zhe‐Xue Quan; Bo Li; Ji Yang; Wei‐Chang Huang; Ming Nie (Environmental Microbiology, 2021)
Summary The foliar surface forms one of the largest aboveground habitats on Earth and maintains plant‐fungus relationships that greatly affect ecosystem functioning. Despite many studies with particular plant species, the foliar epiphytic mycobiome has not been studied across a large number of plant species from different taxa. Using high‐throughput sequencing, we assessed epiphytic mycobiomes on leaf surfaces of 592 plant species in a botanical garden. Plants of angiosperms, gymnosperms, and pteridophytes were involved. Plant taxonomy, leaf side, growing environment, and evolutionary relationships were considered. We found that pteridophytes showed the higher fungal species diversity, stronger mutualistic fungal interactions, and a greater percentage of putative pathogens than gymnosperms and angiosperms. Plant taxonomic group, leaf side, and growing environment were significantly associated with the foliar epiphytic mycobiome, but the similarity of the mycobiomes among plants was not directly related to the distance of the host evolutionary tree. Our results provide a general understanding of the foliar fungal mycobiomes from pteridophytes to angiosperms. These findings will facilitate our understanding of foliar fungal epiphytes and their roles in plant communities and ecosystems.

Structure–activity relationship studies on Pd176252 derivatives leading to discovery of novel GRP receptor antagonist with potent anticancer activity - Ming-jun Yu; Chao Li; Meng He; Yu-ting Zhu; Rui Yang; Sheng-song Deng; Xiao-ming Meng; Ri-sheng Yao (Medicinal Chemistry Research, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

The ATP Level in the mPFC Mediates the Antidepressant Effect of Calorie Restriction - Qian Wang; Ying Kong; Song Lin; Ding-Yu Wu; Jian Hu; Lang Huang; Wen-Si Zang; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Synthesis and biological evaluation of novel 1,3-diphenylurea quinoxaline derivatives as potent anticancer agents - Gui-Zhen Li; Xi-Lin Ouyang; Zu-Yu Mo; Yao Gu; Xiao-Lin Cao; Li Yang; Hai-Tao Tang; Ying-Ming Pan (Medicinal Chemistry Research, 2021)

Application of Plant Print Identification Technology in Salt-resistant Soybean Breeding - Yan Li; Xia Li; Zi-qi Chen; Ying Ma; Guang-yu Yang; Ying Zhang; Ming-chun Sun; Li-hong Zhang; Jin-meng Chu; Jing-mei Lu; Jun Zhu; Ji-hong You (Journal of Plant Growth Regulation, 2021)

Flexible reconfiguration of functional brain networks as a potential neural mechanism of creativity - Junchao Li; Natasza Orlov; Zengjian Wang; Bingqing Jiao; Yibo Wang; Huawei Xu; Hui Yang; Yingying Huang; Yan Sun; Peng Zhang; Rengui Yu; Ming Liu; et al. (Brain Imaging and Behavior, 2021)

Associations between essential microelements exposure and the aggressive clinicopathologic characteristics of papillary thyroid cancer - Ming-Jun Hu; Jia-Liu He; Xin-Ran Tong; Wan-Jun Yang; Huan-Huan Zhao; Guo-Ao Li; Fen Huang (BioMetals, 2021)

OSL chronology of a Palaeolithic site in a humid subtropical mountainous area of southeast China - Jian-hui Jin; Xiao-yang Wang; Zhen-yu Zhou; Yun-ming Huang; Xue-chun Fan; Xin-xin Zuo; Zhi-zhong Li; Zhi-yong Ling; Yong-qing Ren; Shu-tong Li (Journal of Mountain Science, 2021)

Protective effects of SP600125 on mice infected with H1N1 influenza A virus - Yuling Tang; Guanghui Yang; Yuxiang Li; Ming Wang; Gebin Li; Yanxin Hu (Archives of Virology, 2021)

Neuroprotective triterpene saponins from the leaves of Panax notoginseng - Ji-Wu Huang; Yi-Qian Du; Chuang-Jun Li; Jing-Zhi Yang; Jie Ma; Ying-Da Zang; Nai-Hong Chen; Dong-Ming Zhang (Natural Product Research, 2021)

A new species of Pacifides from the Western Pacific Coast and the first fully freshwater species of the maricolan planarian genus Paucumara (Platyhelminthes, Tricladida, Maricola) - Ming-Yi Li; Xin-Yi Ma; Wei-Xuan Li; Ying Yang; Ronald Sluys; Jia-Jia Chen; Shuang-Fei Li; An-Tai Wang (Systematics and Biodiversity, 2021)

A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication - Ran Li; Peng Yang; Ming Li; Wenwen Fang; Xiangpeng Yue; Hojjat Asadollahpour Nanaei; Shangquan Gan; Duo Du; Yudong Cai; Xuelei Dai; Qimeng Yang; Chunna Cao; et al. (Science China Life Sciences, 2021)

HDAC3 Downregulation Improves Cerebral Ischemic Injury via Regulation of the SDC1-Dependent JAK1/STAT3 Signaling Pathway Through miR-19a Upregulation - Hua Fang; Hua-Feng Li; Ming-Hai He; Miao Yang; Jian-Ping Zhang (Molecular Neurobiology, 2021)

Strong in vitro and in vivo cytotoxic effects of two platinum(II) complexes with cryptolepine derivatives - Li-Qin Qin; Zu-Zhuang Wei; Lin Yang; Qi-Pin Qin; Jia-Jing Zeng; Ming-Xiong Tan; Hong Liang (Medicinal Chemistry Research, 2021)

The mechanism and application of high-pressure water jet technology to prevent compound dynamic disaster - Zeng-qiang Yang; Chang Liu; Feng-shuo Li; Lin-ming Dou; Gang-wei Li; Da-wei Wang (Arabian Journal of Geosciences, 2021)

Isolation and characterization of a new cytotoxic polyketide–amino acid hybrid from Thermothelomyces thermophilus ATCC 42464 - Yang-Le Gao; Ming-Liang Zhang; Xue Wang; Huai-Dong Zhang; Jian-Zhong Huang; Li Li (Natural Product Research, 2021)

Quantitative Proteomics Analysis of Sugarcane Ratoon Crop Chlorosis - Ye-Geng Fan; Rong-Fa Chen; Li-Hang Qiu; Zhong-Feng Zhou; Hui-Wen Zhou; Ji-Guang Wei; Xiu-Peng Song; Ting Luo; Prakash Lakshmanan; Xing Huang; Jian-Ming Wu; Yang-Rui Li (Sugar Tech, 2021)

Different posterior hippocampus and default mode network modulation in young APOE ε4 carriers: a functional connectome-informed phenotype longitudinal study - Li Juan Zheng; Li Lin; U. Joseph Schoepf; Akos Varga-Szemes; Rock H. Savage; Han Zhang; Yun Fei Wang; Xin Yuan Zhang; Song Luo; Ya Liu; Gui Fen Yang; Guang Ming Lu; et al. (Molecular Neurobiology, 2021)

Endocrine Dysfunction Following Stroke - Fei Wang; Ming-ying Luo; Lei Zhou; Li Yang; Giuseppe Lanzino; Heng-Jui Chang; George C Wellman (Journal of Neuroimmune Pharmacology, 2021)

A transcription factor TaTCP20 regulates the expression of Ppd-D1b in common wheat - Fan Wei; Tianqi Song; Jianfei Zhou; Jie Cheng; Ruibo Li; Ming Yu; Yunrui Zhang; Yang Yu; Bo Zhang; Xiaoke Zhang (Plant Biotechnology Reports, 2021)

Sphingopyxis microcysteis sp. nov., a novel bioactive exopolysaccharides-bearing Sphingomonadaceae isolated from the Microcystis phycosphere - Xiao-ling Zhang; Gui-xian Li; Ya-ming Ge; Nurhezreen Md Iqbal; Xi Yang; Zhen-dong Cui; Qiao Yang (Antonie van Leeuwenhoek, 2021)

Physiological determinants of biogeography: The importance of metabolic depression to heat tolerance - Ming‐ling Liao; Gao‐yang Li; Jie Wang; David J. Marshall; Tin Yan Hui; Shu‐yang Ma; Yi‐min Zhang; Brian Helmuth; Yun‐wei Dong (Global Change Biology, 2021)
A quantitative understanding of physiological thermal responses is vital for forecasting species distributional shifts in response to climate change. Many studies have focused on metabolic rate as a global metric for analyzing the sublethal effects of changing environments on physiology. Thermal performance curves (TPCs) have been suggested as a viable analytical framework, but standard TPCs may not fully capture physiological responses, due in part to failure to consider the process of metabolic depression. We derived a model based on the nonlinear regression of biological temperature‐dependent rate processes and built a heart rate data set for 26 species of intertidal molluscs distributed from 33°S to ~40°N. We then calculated physiological thermal performance limits with continuous heating using , the temperature at which heart rate is decreased to 50% of the maximal rate, as a more realistic measure of upper thermal limits. Results indicate that heat‐induced metabolic depression of cardiac performance is a common adaptive response that allows tolerance of harsh environments. Furthermore, our model accounted for the high inter‐individual variability in the shape of cardiac TPCs. We then used these TPCs to calculate physiological thermal safety margins (pTSM), the difference between the maximal operative temperature (95th percentile of field temperatures) and of each individual. Using pTSMs, we developed a physiological species distribution model (pSDM) to forecast future geographic distributions. pSDM results indicate that climate‐induced species range shifts are potentially less severe than predicted by a simple correlative SDM. Species with metabolic depression below the optimum temperature will be more thermal resistant at their warm trailing edges. High intraspecific variability further suggests that models based on species‐level vulnerability to environmental change may be problematic. This multi‐scale, mechanistic understanding that incorporates metabolic depression and inter‐individual variability in thermal response enables better predictions about the relationship between thermal stress and species distributions.

miR-34c inhibits PDGF-BB-induced HAVSMCs phenotypic transformation and proliferation via PDGFR-β/SIRT1 pathway - Wei-feng Wan; Xin Zhang; Chang-ren Huang; Li-gang Chen; Xiao-bo Yang; Kun-yang Bao; Tang-ming Peng (Molecular Biology Reports, 2021)
The purpose of this study was to explore the effect of miR-34c on PDGF-BB-induced HAVSMCs phenotypic transformation and proliferation via PDGFR-β/SIRT1 pathway, so as to find a new method for early diagnosis and treatment of cardiovascular disease. HA-VSMCs were treated with platelet-derived growth factor-BB (PDGF-BB) at 0 h, 12 h, 24 h, 48 h or 36 h to explore the optimal time for phenotypic transformation of VSMCs. And then, PDGF-BB-induced HA-VSMCs were transfected with miR-34c mimics/mimics NC and pcDNA3.1-PDGFR-β/pcDNA3.1-NC to observe cell biological behaviour. CCK8 was used to detect cell proliferation activity. Transwell chamber assay was used to detect cell invasion. Early apoptosis was analyzed by flow cytometry. The expression of α-SMA and Smemb was detected by immunofluorescence staining. The expressions of PDGFR-β, IRF9, Acetyl-NF-κB/p65, Acetyl-p53 and CyclinD1 were analyzed by Western blot analysis. The expression of miR-34a, miR-34b and miR-34c was detected by RT-PCR, and the targeting relationship between miR-34c and PDGFR-β was detected by luciferase reporting assay. The results indicated the proliferation and migration of PDGF-BB-induced HA-VSMCs significantly increased, and apoptosis significantly decreased. Besides, α-SMA decreased significantly, while Smemb increased significantly. Furthermore, expressions of PDGFR-β, IRF9, Acetyl-NF-κB/p65, Acetyl-p53 and CyclinD1 increased significantly, and SIRT1 decreased significantly. Experimental results showed that, miR-34c mimics significantly inhibited cell proliferation and migration, and promoted cell apoptosis, and miR-34c inhibitor had the opposite effects. MiR-34c mimics significantly increased α-SMA expression and decreased Smemb expression, while the opposite effects were reflected after transfection with miR-34c inhibitor. Moreover, miR-34c mimics significantly decreased the expressions of PDGFR-β, IRF9, Acetyl-NF-κB/p65, Acetyl-p53 and CyclinD1, and significantly increased the expression of SIRT1, while miR-34c inhibitor had the opposite effects. Luciferase assay confirmed that PDGFR-β was a potential target of miR-34c. Subsequently, PDGF-BB-induced HA-VSMCs were co-transfected with miR-34c mimics and pcDNA3.1-PDGFR-β. The results indicated that PDGFR-β reversed the biological function of miR-34c mimic. The results revealed the potential application value of miR-34c as a marker molecule of phenotypic transformation, providing a potential target for improving phenotypic transformation.

Shear strength and microstructure of silty clay subjected to CaSO4 solution and stability effect on a gypsum dump - Tao Wei; Guoqing Chen; Xiang Sun; Yang Li; Changan Qin; Ming Yan (Bulletin of Engineering Geology and the Environment, 2021)

Vegetation dynamics and climate variability over the past 2000 years inferred from Son Kul marsh in the western Tianshan Mountains - Dong-liang Zhang; Yao-ming Li; Kai-hui Li; Xue-xi Ma; Yun-peng Yang (Journal of Mountain Science, 2021)

Characteristics and Causes of Extreme Rainfall Induced by Binary Tropical Cyclones over China - Mingyang Wang; Fumin Ren; Yanjun Xie; Guoping Li; Ming-Jen Yang; Tian Feng (Asia-Pacific Journal of Atmospheric Sciences, 2021)
Binary tropical cyclones (BTC) often bring disastrous rainfall to China. From the viewpoint of the extreme of the BTC maximum daily rainfall, the characteristics of BTC extreme rainfall (BTCER) during 1960–2018 are analyzed, using daily rainfall data; and some representative large-scale mean flows, in which the associated BTCs are embedded, are analyzed. Results show that the frequency of BTCER shows a decreasing trend [−0.49 (10 yr) −1 ] and is mainly distributed within the BTC heavy rainstorm interval (100 mm ≤ BTCER

Subcellular Localization of the D27 Protein in Sugarcane (Saccharum spp. Hybrids) Using an Optimized Protoplast Isolation, Purification, and Transient Gene Expression Protocol - Zhuan-di Wu; Xin Hu; Feng-gang Zan; Yong-bao Pan; David M. Burner; Zheng-ying Luo; Jia-yong Liu; Li-ping Zhao; Li Yao; Yong Zhao; Xin-long Liu; Hong-ming Xia; et al. (Sugar Tech, 2021)

Effects of hydrological change on the risk of riverine algal blooms: case study in the mid-downstream of the Han River in China - Lisha Shen; Ming Dou; Rui Xia; Guiqiu Li; Baiheng Yang (Environmental Science and Pollution Research, 2021)

Crenobacter intestini sp. nov., Isolated from the Intestinal Tract of Konosirus punctatus - Song-Biao Shi; Jia-Fa Wu; Li-Fang Yang; Ming-Guo Jiang; Cai-Mi Gao; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Marinobacter shengliensis subsp. alexandrii Subsp. Nov., Isolated from Cultivable Phycosphere Microbiota of Highly Toxic Dinoflagellate Alexandrium catenella LZT09 and Description of Marinobacter shengliensis Subsp. shengliensis Subsp. Nov - Xi Yang; Rong Xiang; Nurhezreen Md Iqbal; Yu-Han Duan; Xiao-Ai Zhang; Lei Wang; Lin-Zeng Yu; Jia-Zhou Li; Ming-Fei Sun; Qiao Yang; Chun-Tian Zheng; Shen-Quan Liao (Current Microbiology, 2021)

miR-491-3p is Downregulated in Retinoblastoma and Inhibit Tumor Cells Growth and Metastasis by Targeting SNN - Yang Hu; Ming Zhao; Li Li; Jie Ding; Yu-Min Gui; Tan-Wei Wei (Biochemical Genetics, 2021)
Retinoblastoma (Rb) is the most common pediatric malignant tumor of the eyes. Previous studies demonstrated that miR-491-3p is downregulated in various cancers. However, its function in Rb remains unknown. A total of 15 pairs of primary Rb tissues and adjacent noncancerous tissues were collected. Quantitative real-time PCR (qRT-PCR) was used to investigate the expression profiles of miR-491-3p. qRT-PCR, western blotting and in situ immunocytochemistry were performed to investigate the expression profiles of epithelial–mesenchymal transition-related proteins (E-cadherin, Vimentin and N-cadherin) in Rb tissues and Rb cell lines as well as cell morphology. Cell proliferation was estimated by MTS and colony formation assays. Apoptosis was determined by FACS, cell migration and invasion were analyzed using transwell chambers. MiR-491-3p’s target genes were predicted using target gene prediction databases. The interplay between miR-491-3p and SNN was evaluated through dual luciferase reporter gene assay. MiR-491-3p was significantly downregulated in mixed collection of 15 pairs of Rb tissues and Rb cell lines. Overexpression of miR-491-3p enhanced apoptosis, and significantly suppressed proliferation, migration and invasion of Rb cells. In contrast, the present of miR-491-3p inhibitor showed reversed results which apoptosis decreased, while cell proliferation of ARPE-19 cells increased. In addition, miR-491-3p increased the expression of E-cadherin, and dramatically decreased the expression of Vimentin and N-cadherin in Rb tissues and Rb cell lines, noticeable changes in morphology, too, as cells became less cohesive and more adhering. We found out that SNN was the pairing target of miR-491-3p and result showed that miR-491-3p and SNN interacted with each other. We also found out that the effects of miR-491-3p were in Rb cells were almost entirely canceled out at the overexpression of SNN. Our findings collectively suggest that miR-491-3p is an important tumor suppressor in Rb, which inhibits tumor growth and metastasis in Rb. These implicate it may be explored as a new therapeutic target in Rb.

Simultaneous detection of multiple bacterial and viral aquatic pathogens using a fluorogenic loop‐mediated isothermal amplification‐based dual‐sample microfluidic chip - Qian‐Jin Zhou; Jian‐Fei Lu; Xiu‐Rong Su; Jing‐Lei Jin; Shang‐Yang Li; Yan Zhou; Lei Wang; Xin‐Bin Shao; Yao‐Hua Wang; Mao‐Cang Yan; Ming‐Yun Li; Jiong Chen (Journal of Fish Diseases, 2021)
Rapid and user‐friendly diagnostic tests are necessary for early diagnosis and immediate detection of diseases, particularly for on‐site screening of pathogenic microorganisms in aquaculture. In this study, we developed a dual‐sample microfluidic chip integrated with a real‐time fluorogenic loop‐mediated isothermal amplification assay (dual‐sample on‐chip LAMP) to simultaneously detect 10 pathogenic microorganisms, that is Aeromonas hydrophila , Edwardsiella tarda , Vibrio harveyi , V. alginolyticus , V. anguillarum , V. parahaemolyticus , V. vulnificus , infectious hypodermal and haematopoietic necrosis virus, infectious spleen and kidney necrosis virus, and white spot syndrome virus. This on‐chip LAMP provided a nearly automated protocol that can analyse two samples simultaneously, and the tests achieved limits of detection (LOD) ranging from 10 0 to 10 –1 pg/μl for genomic DNA of tested bacteria and 10 –4 to 10 –5 pg/μl for recombinant plasmid DNA of tested viruses, with run times averaging less than 30 min. The coefficient of variation for the time‐to‐positive value was less than 10%, reflecting a robust reproducibility. The clinical sensitivity and specificity were 93.52% and 85.53%, respectively, compared to conventional microbiological or clinical methods. The on‐chip LAMP assay provides an effective dual‐sample and multiple pathogen analysis, and thus would be applicable to on‐site detection and routine monitoring of multiple pathogens in aquaculture.

Effects of habitat fragmentation on the demography of the critically endangered tree Pterospermum kingtungense (Sterculiaceae) in Yunnan, China - Chun-Ming Yuan; Shan-Shan Zhang; Guo-Ping Yang; Jian Chen; Yun-Fen Geng; Xiao-Shuang Li; Wen-Zhong Yang (Tropical Ecology, 2021)

A CONSTANS-LIKE gene of Nelumbo nucifera could promote potato tuberization - Dingding Cao; Zhongyuan Lin; Longyu Huang; Rebecca Njeri Damaris; Ming Li; Pingfang Yang (Planta, 2021)

Arbuscular mycorrhizal colonization rate of an exotic plant, Galinsoga quadriradiata, in mountain ranges changes with altitude - Gang Liu; Rui-Ling Liu; Wen-Gang Zhang; Ying-Bo Yang; Xiao-Qiong Bi; Ming-Zhu Li; Xiao-Yan Chen; Hua Nie; Zhi-Hong Zhu (Mycorrhiza, 2021)

Pseudomonas laoshanensis sp. nov., isolated from peanut field soil - Ming-Qing Wang; Chu-Shu Zhang; Li-Na Yu; Wei-Qiang Yang; Kun Jiao; Kui-Jie Gong; Xiao-Yuan Chi; Jie Bi; Yu Song; Qing-Li Yang; Jian-Cheng Zhang; Gui-Wen Yang; et al. (Archives of Microbiology, 2021)

A single nucleotide polymorphism variant located in the cis ‐regulatory region of the ABCG2 gene is associated with mallard egg colour - Hehe Liu; Jian Hu; Zhanbao Guo; Wenlei Fan; Yaxi Xu; Suyun Liang; Dapeng Liu; Yunsheng Zhang; Ming Xie; Jing Tang; Wei Huang; Qi Zhang; et al. (Molecular Ecology, 2021)
Avian egg coloration is shaped by natural selection, but its genetic basis remains unclear. Here, we used genome‐wide association analysis and identity by descent to finely map green egg colour to a 179‐kb region of Chr4 based on the resequencing of 352 ducks ( Anas platyrhynchos ) from a segregating population resulting from the mating of Pekin ducks (white‐shelled eggs) and mallards (green‐shelled eggs). We further narrowed the candidate region to a 30‐kb interval by comparing genome divergence in seven indigenous duck populations. Among the genes located in the finely mapped region, only one transcript of the ABCG2 gene (XM_013093252.2) exhibited higher uterine expression in green‐shelled individuals than in white‐shelled individuals, as supported by transcriptome data from four populations. ABCG2 has been reported to encode a protein that functions as a membrane transporter for biliverdin. Sanger sequencing of the whole 30‐kb candidate region (Chr4: 47.41–47.44 Mb) and a plasmid reporter assay helped to identify a single nucleotide polymorphism (Chr4: 47,418,074 G>A) located in a conserved predicted promoter region whose variation may alter ABCG2 transcription activity. We provide a useful molecular marker for duck breeding and contribute data to the research on ecological evolution based on egg colour patterns among birds.

QTL mapping for foxtail millet plant height in multi-environment using an ultra-high density bin map - Qiang He; Hui Zhi; Sha Tang; Lu Xing; Suying Wang; Haigang Wang; Aiying Zhang; Yuhui Li; Ming Gao; Haijin Zhang; Guoqiu Chen; Shutao Dai; et al. (Theoretical and Applied Genetics, 2021)

Down-regulation of MANNANASE7 gene in Brassica napus L. enhances silique dehiscence-resistance - Yu-Long Li; Yan-Kun Yu; Ke-Ming Zhu; Li-Na Ding; Zheng Wang; Yan-Hua Yang; Jun Cao; Li-Zhang Xu; Yao-Ming Li; Xiao-Li Tan (Plant Cell Reports, 2021)

Postsynaptic Targeting and Mobility of Membrane Surface-Localized hASIC1a - Xing-Lei Song; Di-Shi Liu; Min Qiang; Qian Li; Ming-Gang Liu; Wei-Guang Li; Xin Qi; Nan-Jie Xu; Guang Yang; Michael Xi Zhu; Tian-Le Xu (Neuroscience Bulletin, 2021)
Acid-sensing ion channels (ASICs), the main H + receptors in the central nervous system, sense extracellular pH fluctuations and mediate cation influx. ASIC1a, the major subunit responsible for acid-activated current, is widely expressed in brain neurons, where it plays pivotal roles in diverse functions including synaptic transmission and plasticity. However, the underlying molecular mechanisms for these functions remain mysterious. Using extracellular epitope tagging and a novel antibody recognizing the hASIC1a ectodomain, we examined the membrane targeting and dynamic trafficking of hASIC1a in cultured cortical neurons. Surface hASIC1a was distributed throughout somata and dendrites, clustered in spine heads, and co-localized with postsynaptic markers. By extracellular pHluorin tagging and fluorescence recovery after photobleaching, we detected movement of hASIC1a in synaptic spine heads. Single-particle tracking along with use of the anti-hASIC1a ectodomain antibody revealed long-distance migration and local movement of surface hASIC1a puncta on dendrites. Importantly, enhancing synaptic activity with brain-derived neurotrophic factor accelerated the trafficking and lateral mobility of hASIC1a. With this newly-developed toolbox, our data demonstrate the synaptic location and high dynamics of functionally-relevant hASIC1a on the surface of excitatory synapses, supporting its involvement in synaptic functions.

Mechanism of a catastrophic landslide occurred on May 12, 2019, Qinghai Province, China - Min Xia; Guang Ming Ren; Xi Li Yang (Landslides, 2021)

Differential response of microbial diversity and abundance to hydrological residual time and age in cascade reservoirs - Yihong Yue; Fushun Wang; Zhiwei Fu; Yi Tang; Jing Ma; Yong Qin; Meng Li; Ming Yang; Xue-Ping Chen (Journal of Soils and Sediments, 2021)

The reproductive regulation of LPXRFa and its receptor in the hypothalamo-pituitary-gonadal axis of the spotted scat (Scatophagus argus) - Yi Zhai; Si-Ping Deng; Jian-Ye Liu; Dong-Neng Jiang; Yang Huang; Chun-Hua Zhu; Guang-Li Li; Ming-Hui Li (Fish Physiology and Biochemistry, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex - Zhijun Zhang; Hongxing Zhang; Chun-Ming Xie; Meng Zhang; Yachen Shi; Ruize Song; Xiang Lu; Haisan Zhang; Kun Li; Bi Wang; Yongfeng Yang; Xianrui Li; et al. (Science China Life Sciences, 2021)

Astrocyte-Derived Lactate Modulates the Passive Coping Response to Behavioral Challenge in Male Mice - Ya-Nan Yin; Jian Hu; Yi-Li Wei; Ze-Lin Li; Zhou-Cai Luo; Rui-Qi Wang; Ke-Xin Yang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Potential Himalayan community turnover through the Late Pleistocene - Feng Dong; Chih-Ming Hung; Shou-Hsien Li; Xiao-Jun Yang (Climatic Change, 2021)

Long-term (1975–2016) variations of aerosol optical depth in South Central Hebei Plain, China, and its correlations with East Asian monsoon and economic activities - Lingyun Zhang; Fuxing Li; Qiang Wei; Xiaohui Yang; Wei Wang; Ming Yan (Arabian Journal of Geosciences, 2021)

Phytochemical and antitumor studies on Cynanchum mongolicum (Maxim.) Kom - Yong-Cheng Yang; Yan-Ming Wang; Zi-Jian Rong; Li-Na Hong; Qian Zhang; Jing-Ming Jia; An-Hua Wang (Natural Product Research, 2020)

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Natural products development under epigenetic modulation in fungi - Chi-Ying Li; Yu-Ming Chung; Yang-Chang Wu; Attila Hunyadi; Clay C. C. Wang; Fang-Rong Chang (Phytochemistry Reviews, 2020)

Downregulation of Adhesion Molecule CHL1 in B Cells but Not T Cells of Patients with Major Depression and in the Brain of Mice with Chronic Stress - C. R. Yang; L. Ning; F. H. Zhou; Q. Sun; H. P. Meng; Z. Han; Y. Liu; W. Huang; S. Liu; X. H. Li; B. Zheng; Dong Ming; et al. (Neurotoxicity Research, 2020)

Anxiolytic Effects of 8-O-Acetyl Shanzhiside Methylester on Acute and Chronic Anxiety via Inflammatory Response Inhibition and Excitatory/Inhibitory Transmission Imbalance - Ting Sun; Li Luo; Qin-Qin Tian; Wen-Ju Wang; Qing-Qing Liu; Le Yang; Kun Zhang; Wei Zhang; Ming-Gao Zhao; Qi Yang (Neurotoxicity Research, 2020)
Anxiety leads to a global decline in quality of life and increase in social burden. However, treatments are limited, because the molecular mechanisms underlying complex emotional disorders are poorly understood. We explored the anxiolytic effects of 8-O-acetyl shanzhiside methylester (8-OaS), an active component in Lamiophlomis rotata ( L . rotata ; Benth.) or Kudo, a traditional herb that has been shown to be effective in the clinical treatment of chronic pain syndromes in China. Two mouse anxiety models were used: forced swimming stress (FSS)–induced anxiety and complete Freund’s adjuvant (CFA)–induced chronic inflammatory pain. All animal behaviors were analyzed on the elevated plus maze and in the open-field test. 8-OaS significantly ameliorated anxiety-like behaviors in both anxiety models and inhibited the translation enhancement of GluN2A, GluN2B, and PSD95. Moreover, a reduction in GABA receptors disrupted the excitatory/inhibitory (E/I) balance in the basolateral amygdala (BLA), indicated by increased excitatory and decreased inhibitory presynaptic release. 8-OaS also blocked microglia activation and reduced the phosphorylation of p38, c-Jun N-terminal kinase (JNK), NF-κB p65, and tumor necrosis factor alpha (TNF-α) in the BLA of anxiety mice. 8-OaS exhibits obvious anxiolytic effects by regulating the excitatory/inhibitory (E/I) synaptic transmission and attenuating inflammatory responses in the BLA.

Comparison Between the Gut Microbiota in Different Gastrointestinal Segments of Large-Tailed Han and Small-Tailed Han Sheep Breeds with High-Throughput Sequencing - Guangli Yang; Shuhong Zhang; Zhiqiang Li; Jie Huang; Yan Liu; Ying Liu; Qiankun Wang; Xiangyu Li; Yongfeng Yan; Ming Li (Indian Journal of Microbiology, 2020)

Dietary lipid concentrations influence growth, body composition, morphology of the liver and mid-intestine, and antioxidant status of marbled eel (Anguilla marmorata) - Shi-Jun Chen; Peng Liu; You-Ming Jia; Hong-Ping Liao; Shao-Xuan Zhu; Li-Liu Zhou; Xue-Ming Dan; Li Liu; Jia-Hao Li; Su-Bi Zheng; Jun-Jiang Yang; Lian Gan (Aquaculture International, 2020)

An Experimental and Analytical Research on the Evolution of Mining Cracks in Deep Floor Rock Mass - Juntao Chen; Jinhai Zhao; Shichuan Zhang; Yi Zhang; Fan Yang; Ming Li (Pure and Applied Geophysics, 2020)

Synthesis and molecular docking studies of novel pyrimidine derivatives as potential antibacterial agents - Xue-Qian Bai; Chun-Shi Li; Ming-Yue Cui; Ze-Wen Song; Xing-Yu Zhou; Chao Zhang; Yang Zhao; Tian-Yi Zhang; Tie-Yan Jiang (Molecular Diversity, 2020)

Incorporated maize residues will induce more accumulation of new POC in HF compared with that in LF soils: a comparison of different residue types - Yang Wang; Shuangyi Li; Yingde Xu; Ming Li; Te Shan; Weijun Zhang; Xu Liu; Muhammad Farhan Saeed; Jingkuan Wang (Journal of Soils and Sediments, 2020)

Body weight, CYP2C19, and P2Y12 receptor polymorphisms relate to clopidogrel resistance in a cohort of Chinese ischemic stroke patients with aspirin intolerance - Zhiqiang Li; Wanqing Dong; Daorong Yang; Linhai Sun; Xianjun He; Huanhuan Hu; Jianping Zhang; Chunyu Wang; Yulin Li; Ming Zhao; Yu Kong; Yan Wang (European Journal of Clinical Pharmacology, 2020)

Nobiletin Regulates ROS/ADMA/DDAHII/eNOS/NO Pathway and Alleviates Vascular Endothelium Injury by Iron Overload - Zhiqing Wang; Bin Yang; Xuepiao Chen; Qing Zhou; Hongwei Li; Shuping Chen; Dong Yin; Huan He; Ming He (Biological Trace Element Research, 2020)

Characterization and functional analysis of Krtap11-1 during hair follicle development in Angora rabbits (Oryctolagus cuniculus) - Shuang Liang; Zhiyuan Bao; Bohao Zhao; Tong Zhou; Jiali Li; Ming Liu; Shuaishuai Hu; Naisu Yang; Yang Chen; Xinsheng Wu (Genes & Genomics, 2020)

Tectonic nature of the NE Asian continental margin during the Late Jurassic–Early Cretaceous: constraints from the geochronology and geochemistry of igneous rocks in the NE North China Craton - Xiao-Ming Zhang; Wen-Liang Xu; Chen-Yang Sun; Feng Wang; Yu Li (International Geology Review, 2020)

One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko - Wan-Rong Niu; Cong-Liang Guo; Deng-Ji Lou; Rui-Ting Li; Qiao Xiang; Yu-Lin Zou; Xiu-Ming Cui; Xiao-Yan Yang (Natural Product Research, 2020)

Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice - Qi Yang; Li Luo; Ting Sun; Le Yang; Li-Fei Cheng; Yan Wang; Qing-Qing Liu; An Liu; Hai-Yan Liu; Ming-Gao Zhao; Sheng-Xi Wu; Bin Feng (Psychopharmacology, 2020)

Genetic diversity comparisons of wild populations of Nelumbo nucifera (Nelumbonaceae) in Russia and China using microsatellite markers - Zhi-Zhong Li; Md. Rabiul Islam; Shi-Xu Huang; Dan Yang; Yeshitila Mekbib; Popova Svetlana; Hong-Bing Sun; Jin-Ming Chen; Xing-Yu Yang (Plant Systematics and Evolution, 2020)

Competition between fulvic acid and phosphate-mediated surface properties and transport of titanium dioxide nanoparticles in sand porous media - Shiqi Wang; Duo Li; Mo Zhang; Ming Chen; Nan Xu; Li Yang; Jianping Chen (Journal of Soils and Sediments, 2020)

Effects of biochar properties on the bioremediation of the petroleum-contaminated soil from a shale-gas field - Hong-Yang Ren; Zi-Jing Wei; Yan Wang; Yuan-Peng Deng; Ming-Yu Li; Bing Wang (Environmental Science and Pollution Research, 2020)

Effects of moss-dominated biocrusts on soil detachment by overland flow in the Three Gorges Reservoir Area of China - Guan-hua Zhang; Wen-feng Ding; Jian Pu; Jian-ming Li; Feng Qian; Bao-yang Sun (Journal of Mountain Science, 2020)

Small RNA profiling reveal regulation of microRNAs in field peanut pod rot pathogen infection - Mian Wang; Chao-xin Zhang; Li-juan Pan; Tong Wang; Na Chen; Ming-na Chen; Zhen Yang; Xin-gang Guo; Shan-lin Yu; Xiao-yuan Chi (Biologia, 2020)

Antitumor activity on human bladder cancer T-24 cells and composition analysis of the core of Camellia osmantha fruit - Xi-Lin Ouyang; Li Yang; Lei Huang; Ying-Ming Pan (Natural Product Research, 2020)

Early use of dexamethasone increases Nr4a1 in Kupffer cells ameliorating acute liver failure in mice in a glucocorticoid receptor-dependent manner - Jing-wen Deng; Qin Yang; Xiao-peng Cai; Jia-ming Zhou; Wei-gao E; Yan-dong An; Qiu-xian Zheng; Meng Hong; Yan-li Ren; Jun Guan; Gang Wang; Shu-jing Lai; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Sauchinone: a prospective therapeutic agent-mediated EIF4EBP1 down-regulation suppresses proliferation, invasion and migration of lung adenocarcinoma cells - Sheng-Qian Li; Jing Feng; Ming Yang; Xiao-Peng Ai; Mei He; Fu Liu (Journal of Natural Medicines, 2020)

Surface heterogeneity mediated transport of hydrochar nanoparticles in heterogeneous porous media - Jing Yang; Ming Chen; Han Yang; Nan Xu; Gang Feng; Zuling Li; Chunming Su; Dengjun Wang (Environmental Science and Pollution Research, 2020)

Intrusion of Fall Armyworm (Spodoptera frugiperda) in Sugarcane and Its Control by Drone in China - Xiu-Peng Song; Yong-Jian Liang; Xiao-Qiu Zhang; Zhen-Qiang Qin; Jin-Ju Wei; Yang-Rui Li; Jian-Ming Wu (Sugar Tech, 2020)

Effects of Spray Parameters of Drone on the Droplet Deposition in Sugarcane Canopy - Xiao-Qiu Zhang; Xiu-Peng Song; Yong-Jian Liang; Zhen-Qiang Qin; Bao-Qing Zhang; Jin-Ju Wei; Yang-Rui Li; Jian-Ming Wu (Sugar Tech, 2020)

A fundamental theorem for eco-environmental surface modelling and its applications - Tianxiang Yue; Na Zhao; Yu Liu; Yifu Wang; Bin Zhang; Zhengping Du; Zemeng Fan; Wenjiao Shi; Chuanfa Chen; Mingwei Zhao; Dunjiang Song; Shihai Wang; et al. (Science China Earth Sciences, 2020)

DNA Methylation Analysis of the NR3C1 Gene in Patients with Schizophrenia - Linlin Liu; Jian Wu; Lili Qing; Jiajue Li; Hao Yang; Aicen Ji; Ming Yan; Liping Hu; Shengjie Nie (Journal of Molecular Neuroscience, 2020)

TMEM88 modulates the secretion of inflammatory factors by regulating YAP signaling pathway in alcoholic liver disease - Liang-yun Li; Chen-chen Yang; Su-wen Li; Yu-min Liu; Hao-dong Li; Shuang Hu; Hong Zhou; Jin-liang Wang; Hang Shen; Xiao-ming Meng; Jun Li; Tao Xu (Inflammation Research, 2020)

Privet golden leaves adapt unexpectedly well to light changes - Ming Yuan; Bo Huang; Li-Hua Dong; Qiao-Hong Han; Yong Yang; Chun-Bang Ding; Chao Hu; Yang-Er Chen; Zhong-Wei Zhang; Shu Yuan (Horticulture, Environment, and Biotechnology, 2020)

Seasonal abundance and activity of the tick Dermacentor everestianus (Acari: Ixodidae) in the Tibetan Plateau, China - Ming Liu; Tuo Li; Jia Yang; Si-Si Li; Zhi-Jun Yu; Jing-Ze Liu (Experimental and Applied Acarology, 2020)

Influences of ABC transporter and CYP3A4/5 genetic polymorphisms on the pharmacokinetics of lenvatinib in Chinese healthy subjects - Jiaming Li; Xiaoqian Wang; Chen Ning; Zhaoyu Wang; Yao Wang; Ming Zheng; Siliang Zhang; Yang Lu; Yongjie Zhang; Ning Li; Xijing Chen; Di Zhao (European Journal of Clinical Pharmacology, 2020)

Transcriptome Analysis of Two Strains of Proteus mirabilis with Swarming Migration Deficiency Isolated from Patients with Urinary Tract Infection - Liang Peng; Ding-Qiang Chen; Guan-Ming Jiang; Jing-Yi Ou; Qiao Jiang; Li-Ting Zeng; Yi Xiao; Qiong-Yan Jiang; Ling Yang; Ning Sun (Current Microbiology, 2020)

Naphthalene exerts non-target effects on the abundance of active fungi by stimulating basidiomycete abundance - Li-ying Lan; Li Zhang; Ya Shen; Jian Zhang; Wan-qin Yang; Zhen-feng Xu; Yang Liu; Shu-qin He; Wei Zhou; Han Li; Li-xia Wang; Si-ning Liu; et al. (Journal of Mountain Science, 2020)

Single B cells reveal the antibody responses of rhesus macaques immunized with an inactivated enterovirus D68 vaccine - Huiwen Zheng; Zening Yang; Bingxiang Li; Heng Li; Lei Guo; Jie Song; Dongpei Hou; Nan Li; Jinxi Yang; Qiongwen Wu; Ming Sun; Longding Liu (Archives of Virology, 2020)

Reinvestigation of the substrate specificity of a reverse prenyltransferase NotF from Aspergillus sp. MF297-2 - Keyan Yang; Shu-Ming Li; Xiaoqing Liu; Aili Fan (Archives of Microbiology, 2020)

Single-cell transcriptome analysis of the novel coronavirus (SARS-CoV-2) associated gene ACE2 expression in normal and non-obstructive azoospermia (NOA) human male testes - Xixi Liu; Yidong Chen; Wenhao Tang; Li Zhang; Wei Chen; Zhiqiang Yan; Peng Yuan; Ming Yang; Siming Kong; Liying Yan; Jie Qiao (Science China Life Sciences, 2020)

The trichome-specific acetolactate synthase NtALS1 gene, is involved in acylsugar biosynthesis in tobacco (Nicotiana tabacum L.) - Ai-Xia Chang; Biao Chen; Ai-Guo Yang; Ri-Sheng Hu; Quan-Fu Feng; Ming Chen; Xiao-Ning Yang; Cheng-Gang Luo; Yang-Yang Li; Yuan-Ying Wang (Planta, 2020)

Change in hydraulic properties of the rhizosphere of maize under different abiotic stresses - Di Wang; Yang Gao; Ming Li; Craig J. Sturrock; Andrew S. Gregory; Xiaoxian Zhang (Plant and Soil, 2020)

Selenium accumulation characteristics of Cyphomandra betacea (Solanum betaceum) seedlings - Linjin Lin; Jing Sun; Tonghao Cui; Xiong Zhou; Ming’an Liao; Yunmin Huan; Liu Yang; Caifang Wu; Xianmin Xia; Yuxi Wang; Zhiyu Li; Jinpeng Zhu; et al. (Physiology and Molecular Biology of Plants, 2020)

Astrocytic GABAB Receptors in Mouse Hippocampus Control Responses to Behavioral Challenges through Astrocytic BDNF - Ji-Hong Liu; Ze-Lin Li; Yi-Si Liu; Huai-De Chu; Neng-Yuan Hu; Ding-Yu Wu; Lang Huang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2020)

Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family - Juan Zhang; Yanjun Liu; Ming Li; Xiaoxu Ge; Ying Wang; Xin Huang; Di Yang; Rong Zhang; Yating Chen; Ming Lu; Jun Yin; Mingqiang Song; et al. (Molecular and Cellular Biochemistry, 2020)

Recommended turbulent energy dissipation rate for biomass and lipid production of Scenedesmus obliquus in an aerated photosynthetic culture system - Mei An; Songqi Yang; Haiming Wu; Guanghong Luo; Ming Li (Environmental Science and Pollution Research, 2020)

Comparative transcriptomic analysis of fireflies (Coleoptera: Lampyridae) to explore the molecular adaptations to fresh water - Qi‐Lin Zhang; Hong‐Wei Li; Zhi‐Xiang Dong; Xiao‐Jie Yang; Lian‐Bing Lin; Jun‐Yuan Chen; Ming‐Long Yuan (Molecular Ecology, 2020)
Aquatic insects are well adapted to freshwater environments, but the molecular basis of these adaptations remains largely unknown. Most firefly species (Coleoptera: Lampyridae) are terrestrial, but the larvae of several species are aquatic. Here, larval and adult transcriptomes from Aquatica leii (freshwater) and Lychnuris praetexta (terrestrial) were generated to test whether the genes associated with metabolic efficiency and morphology have undergone adaptive evolution to fresh water. The aquatic fireflies had a significantly lower ratio of nonsynonymous to synonymous substitutions than the terrestrial insects, indicating a genomewide evolutionary constraint in the aquatic fireflies. We identified 341 fast‐evolving genes and 116 positively selected genes in the aquatic fireflies. Of these, 76 genes exhibiting both fast evolution and positive selection were primarily involved in ATP production, energy metabolism and the hypoxia response. We identified 7,271 differentially expressed genes (DEGs) in A . leii (adults versus larvae) and 8,309 DEGs in L . praetexta (adults versus larvae). DEGs specific to the aquatic firefly ( n = 1,445) were screened via interspecific comparisons ( A . leii versus L . praetexta ) and were significantly enriched for genes involved in metabolic efficiency (e.g., ATP production, hypoxia, and immune responses) and certain aspects of morphology (e.g., cuticle chitin, tracheal and compound eye morphology). These results indicate that sequence and expression‐level changes in genes associated with both metabolic efficiency and morphological attributes related to the freshwater lifestyle contributed to freshwater adaptation in fireflies. This study provides new insights into the molecular mechanisms of aquatic adaptation in insects.

Structure and Functional Diversity of Surface Bacterioplankton Communities in an Overwintering Habitat for Large Yellow Croaker, Pseudosciaena crocea, of the Southern East China Sea - Wen Yang; Shi-Zhan Zheng; Shou-Heng Zhou; Li Zhao; Jin-Yong Zhu; Betina Lukwambe; Regan Nicholaus; Cheng-Hua Li; Zhong-Ming Zheng (Frontiers in Marine Science, 2020)

Antifungal, anti-inflamatory and neuritogenic activity of newly-isolated compounds from Disporopsis aspersa - Fang-Li Gang; Feng Zhu; Chao-Fu Yang; Xiao-Ting Li; Hua Yang; Ming-Xia Sun; Wen-Jun Wu; Ji-Wen Zhang (Natural Product Research, 2020)

A review of the estimation of downward surface shortwave radiation based on satellite data: Methods, progress and problems - Husi Letu; Jiancheng Shi; Ming Li; Tianxing Wang; Huazhe Shang; Yonghui Lei; Dabin Ji; Jianguang Wen; Kun Yang; Liangfu Chen (Science China Earth Sciences, 2020)

Genome-wide identification of the NPR1-like gene family in Brassica napus and functional characterization of BnaNPR1 in resistance to Sclerotinia sclerotiorum - Zheng Wang; Lu-Yue Ma; Xiao Li; Feng-Yun Zhao; Rehman Sarwar; Jun Cao; Yu-Long Li; Li-Na Ding; Ke-Ming Zhu; Yan-Hua Yang; Xiao-Li Tan (Plant Cell Reports, 2020)

Mapping and characterization of major QTL for spike traits in common wheat - Cheng-Hao Kuang; Xiao-Fang Zhao; Ke Yang; Zhi-Peng Zhang; Li Ding; Zhi-En Pu; Jian Ma; Qian-Tao Jiang; Guo-Yue Chen; Ji-Rui Wang; Yu-Ming Wei; You-Liang Zheng; et al. (Physiology and Molecular Biology of Plants, 2020)

Large paleo-rockslide induced by buckling failure at Jiasian in Southern Taiwan - Che-Ming Yang; Keng-Hao Kang; Shun-Hsing Yang; Kuo-Wei Li; Hui-Jung Wang; Yin-Tsan Lee; Kuei-Kun Lin; Yii-Wen Pan; Jyh-Jong Liao (Landslides, 2020)

Correction to: Simulated microgravity significantly altered metabolism in epidermal stem cells - Bin-Bin Li; Zheng-Yang Chen; Nan Jiang; Song Guo; Jia-Qi Yang; Shao-Bin Chai; Hong-Feng Yan; Pei-Ming Sun; Gang Hu; Tao Zhang; Bing-Xin Xu; Hong-Wei Sun; et al. (In Vitro Cellular & Developmental Biology - Animal, 2020)

Comparison of third-generation sequencing approaches to identify viral pathogens under public health emergency conditions - Yang Li; Xiao-zhou He; Ming-hui Li; Bo Li; Meng-jie Yang; Yao Xie; Yi Zhang; Xue-jun Ma (Virus Genes, 2020)

A DTW distance-based seismic waveform clustering method for layers of varying thickness - Zhong Hong; Kun-Hong Li; Ming-Jun Su; Guang-Min Hu; Jun Yang; Gai Gao; Bin Hao (Applied Geophysics, 2020)

Design, synthesis and cholinesterase inhibitory activity of α -mangostin derivatives - Xiao-Qian Chi; Bo Hou; Liu Yang; Cheng-Ting Zi; Yong-Feng Lv; Jin-Yu Li; Fu-Cai Ren; Ming-Yan Yuan; Jiang-Miao Hu; Jun Zhou (Natural Product Research, 2020)

Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines - Neng-Yuan Hu; Ya-Ting Chen; Qian Wang; Wei Jie; Yi-Si Liu; Qiang-Long You; Ze-Lin Li; Xiao-Wen Li; Sophie Reibel; Frank W. Pfrieger; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2020)

Spatio-temporal characteristics of agro-climatic indices and extreme weather events during the growing season for summer maize (Zea mays L.) in Huanghuaihai region, China - Zhentao Zhang; Xiaoguang Yang; Zhijuan Liu; Fan Bai; Shuang Sun; Jiayi Nie; Jiqing Gao; Bo Ming; Ruizhi Xie; Shaokun Li (International Journal of Biometeorology, 2020)

Parametric study of integrity on the mechanical properties of transversely isotropic rock mass using DEM - Jiu-yang Huan; Ming-ming He; Zhi-qiang Zhang; Ning Li (Bulletin of Engineering Geology and the Environment, 2020)

Establishment and characterization of an immortalized human chondrocyte cell line - Jiashu Yang; Yuting Tang; Wensun Chen; Ming Zhang; Fangling Hong; Dawei Yang; Qianyi Bao; Ying Yang; Yucui Jin; Lingyun Li; Changyan Ma (Biotechnology Letters, 2020)

Phylogenetic patterns of shrub communities along the longitudinal and latitudinal gradients on the northeastern Qinghai–Tibetan Plateau - Yuan-ming Xiao; Lu-cun Yang; Xiu-qing Nie; Chang-bin Li; Feng Xiong; Guo-ying Zhou (Journal of Mountain Science, 2020)

Induced defense responses against Rhizoctonia solani in rice seedling by a novel antifungalmycin N2 from Streptomyces sp. N2 - Shuai-wen Zhang; Yong Yang; Zhi-ming Wu; Kun-tai Li (Australasian Plant Pathology, 2020)

Aspergillolide, a new 12-membered macrolide from sea cucumber-derived fungus Aspergillus sp. S-3-75 - Jun-Jie Tan; Xiao-Yu Liu; Yang Yang; Feng-Hua Li; Chang-Heng Tan; Yi-Ming Li (Natural Product Research, 2020)

AAV/BBB-Mediated Gene Transfer of CHIP Attenuates Brain Injury Following Experimental Intracerebral Hemorrhage - Shuo Zhang; Zheng-wei Hu; Hai-yang Luo; Cheng-yuan Mao; Mi-bo Tang; Yu-sheng Li; Bo Song; Yao-he Wang; Zhong-xian Zhang; Qi-meng Zhang; Li-yuan Fan; Yao Zhang; et al. (Translational Stroke Research, 2020)

Blockade of c-Src Within the Paraventricular Nucleus Attenuates Inflammatory Cytokines and Oxidative Stress in the Mechanism of the TLR4 Signal Pathway in Salt-Induced Hypertension - Qing Yang; Xiao-Jing Yu; Qing Su; Qiu-Yue Yi; Xin-Ai Song; Xiao-Lian Shi; Hong-Bao Li; Jie Qi; Guo-Qing Zhu; Yu-Ming Kang (Neuroscience Bulletin, 2020)

Xanthohumol protects neuron from cerebral ischemia injury in experimental stroke - Yang Jiao; Yuze Cao; Xiaoyu Lu; Jianjian Wang; Aigul Saitgareeva; Xiaotong Kong; Chang Song; Jie Li; Kuo Tian; Shuoqi Zhang; Ming Bai; Shuang Li; et al. (Molecular Biology Reports, 2020)

Researches on the Internal Molecular Weight Uniformity of Chitosan Biomaterials - Xuqian Lang; Yang Li; Guohui Sun; Zhongzheng Zhou; Jing Li; Chao Feng; Ming Kong; Ya Liu; Xiaojie Cheng; Xiguang Chen (Journal of Ocean University of China, 2020)

Separation and preparation of N-glycans based on ammonia-catalyzed release method - Meifang Yang; Ming Wei; Chengjian Wang; Yu Lu; Wanjun Jin; Xi Gao; Cheng Li; Langhong Wang; Linjuan Huang; Zhongfu Wang (Glycoconjugate Journal, 2020)

Identification, characterization, and functional prediction of circular RNAs in maize - Yang Han; Xinxin Li; Yan Yan; Ming-Hua Duan; Jian-Hong Xu (Molecular Genetics and Genomics, 2020)

EDNRB Reverses Methylprednisolone-Mediated Decrease in Neural Progenitor Cell Viability via Regulating PI3K/Akt Pathway and lncRNA Expression - Shiyuan Li; Ming Zeng; Lin Yang; Jianqi Yang; Jianshao Tan; Hongye Guan; Manyuan Kuang (Journal of Molecular Neuroscience, 2020)

Simulated microgravity significantly altered metabolism in epidermal stem cells - Bin-Bin Li; Zheng-Yang Chen; Nan Jiang; Song Guo; Jia-Qi Yang; Shao-Bin Chai; Hong-Feng Yan; Pei-Ming Sun; Gang Hu; Tao Zhang; Bing-Xin Xu; Hong-Wei Sun; et al. (In Vitro Cellular & Developmental Biology - Animal, 2020)
Simulated microgravity can significantly affect various cell types and multiple systems of the human body, such as cardiovascular system, skeletal muscle system, and immune system, and is known to cause anemia and loss of electrolyte and fluids. Epidermal stem cells (EpSCs) were cultured in a rotary cell culture system (RCCS) bioreactor to simulate microgravity. The metabolites of EpSCs were identified by liquid chromatography-mass spectrometry (LC-MS). Compared with normal gravity (NG) group, a total of 57 different metabolites of EpSCs were identified ( P < 0.05, VIP > 1), including lipids and lipid-like molecules (51 molecules), amino acids (5 molecules), nucleosides, nucleotides, and analogues (1 molecule). According to the partial least squares discriminant analysis (PLS-DA) score plot, a VIP > 1 and P < 0.05 were obtained for the 57 different metabolites, of which 23 molecules were significantly downregulated and 34 were significantly upregulated in simulated microgravity (SMG) group. These results showed that SMG has a significant impact on different pathways, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis indicated that multiple pathways were involved, mainly the amino acid metabolism pathway, lipid metabolism pathway, membrane transport pathway, and cell growth and death pathways. Thus, the metabolic profile of EpSCs was changed under SMG. Exploring the metabolic profile of EpSCs would be helpful to further understand the growth characteristics of EpSCs under SMG, which will provide a new approach to explore the metabolomics mechanism of stress injury and repair trauma under SMG.

Multi-hole joint acquisition of a 3D-RVSP in a karst area: Case study in the Wulunshan Coal Field, China - Ming-Shun Hu; Dong-Ming Pan; Fu-Bao Zhou; Juan-Juan Li; Yang-Zhou Wang; Shen-En Chen; Yong-Zhong Xu (Applied Geophysics, 2020)

Analysis of nicotine-induced metabolic changes in Blakeslea trispora by GC-MS - Yang Liu; You-ran Shao; Xiang-yu Li; Zhi-ming Wang; Li-rong Yang; Yu-zhou Zhang; Mian-bin Wu; Jian-ming Yao (Journal of Zhejiang University-SCIENCE B, 2020)

An accounting of the external environmental costs of coal in Inner Mongolia using the pollution damage method - Hao-Dong Lv; Jin-Sheng Zhou; Lin Yang; Yi-Ming Li; Lu Liu (Environment, Development and Sustainability, 2020)

Antifungal Action of Antifungalmycin N2 Against Rhizoctonia solani by Disrupting Cell Membrane and Inhibiting Succinate Dehydrogenase - Shuai-wen Zhang; Zhi-ming Wu; Yong Yang; Kun-tai Li (Current Microbiology, 2020)

Analysing post-earthquake landslide susceptibility using multi-temporal landslide inventories — a case study in Miansi Town of China - Ning Li; Chuan Tang; Tao Yang; Ming Chen (Journal of Mountain Science, 2020)

Genome-wide identification and expression analysis of the StSWEET family genes in potato (Solanum tuberosum L.) - Ming Li; Haijuan Xie; Miaomiao He; Wang Su; Yongzhi Yang; Jian Wang; Guangji Ye; Yun Zhou (Genes & Genomics, 2020)

The false smut pathogen Ustilaginoidea virens requires rice stamens for false smut ball formation - Jing Fan; Jie Liu; Zhi‐You Gong; Pei‐Zhou Xu; Xiao‐Hong Hu; Jin‐Long Wu; Guo‐Bang Li; Juan Yang; Yu‐Qiu Wang; Yu‐Feng Zhou; Shuang‐Cheng Li; Li Wang; et al. (Environmental Microbiology, 2020)
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The disease is characterized by the transformation of individual rice florets into false smut balls, which is caused by the fungal pathogen Ustilaginoidea virens . To date, little is known about the host factors required for false smut ball formation by U . virens . In this study, we identified histological determinants for the formation of false smut balls by inoculating U . virens into rice floral mutants defective with respect to individual floral parts. The results showed that U . virens could form mature false smut balls in rice floral mutants with defective pistils, but failed to develop false smut balls in the superwoman mutant lacking stamens, identifying that U . virens requires rice stamens to complete its infection cycle. Comparative transcriptome analysis indicated a list of candidate host genes that may facilitate nutrient acquisition by U . virens from the rice stamens, such as SWEET11 , SWEET14 and SUT5 , and genes involved in the biosynthesis of trehalose and raffinose family sugars. These data pinpoint rice stamens as the key target organ of U . virens infection and provide a valuable starting point for dissecting the molecular mechanism of false smut ball formation.

Evidence for the paternal mitochondrial DNA in the crucian carp-like fish lineage with hybrid origin - Shi Wang; Ni Jiao; Lu Zhao; Meiwen Zhang; Pei Zhou; Xuexue Huang; Fangzhou Hu; Conghui Yang; Yuqin Shu; Wuhui Li; Chun Zhang; Min Tao; et al. (Science China Life Sciences, 2020)

The application of the ‘Gene-deletor’ technology in banana - Chun-hua Hu; Qiao-song Yang; Xiu-hong Shao; Tao Dong; Fang-cheng Bi; Chun-yu Li; Gui-ming Deng; Yi Li; Gan-jun Yi; Tong-xin Dou (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)
Banana ( Musa spp.) is an important tropical crop. Banana industry is under biotic and abiotic stresses such as Fusarium wilt, typhoon, cold stress. Genetic engineering offers a powerful strategy to create germplasm of banana with enhanced resistance. The safety of genetically modified organisms has become a bottleneck restricting the popularization and application of genetically modified technology. In this study, a candidate promoter, LEAFY (LFY) for expression and flower initiation in Arabidopsis , was cloned and constructed to ‘Gene-deletor’ vector. Histochemical β-glucuronidase (GUS) staining results showed that the ‘Gene-deletor’ vector driven by LFY promoter could lead to 88.5% excision efficiency from Arabidopsis seeds based on more than 200 T 3 progeny examined per event. GUS staining was found to be partially negative in transgenic bananas, however, polymerase chain reaction could still detect the presence of large fragments of the vector. These results suggest that although LFY promoter could not completely drive the ‘Gene-deletor’ vector to achieve the effect of complete elimination of exogenous gene in bananas, its efficiency of eliminating exogenous gene laid a theoretical foundation for cloning banana fruit-specific promoters, that is, ‘non-transgenic’ GM bananas.

Antidepressant Drugs Correct the Imbalance Between proBDNF/p75NTR/Sortilin and Mature BDNF/TrkB in the Brain of Mice with Chronic Stress - C. R. Yang; X. Y. Zhang; Y. Liu; J. Y. Du; R. Liang; M. Yu; F. Q. Zhang; X. F. Mu; F. Li; L. Zhou; F. H. Zhou; F. J. Meng; et al. (Neurotoxicity Research, 2020)

Uptake and accumulation of pentachloronitrobenzene in pak choi and the human health risk - Ming Li; Guanghui Xu; Rui Yu; Yang Wang; Yong Yu (Environmental Geochemistry and Health, 2020)

Effects of topography on dynamic responses of single piles under vertical cyclic loading - Li-ming Qu; Xuan-ming Ding; Chong-rong Wu; Yong-hong Long; Jin-chuan Yang (Journal of Mountain Science, 2020)

Water and heat availability are drivers of the aboveground plant carbon accumulation rate in alpine grasslands on the Tibetan Plateau - Jian Sun; Tian‐Cai Zhou; Miao Liu; You‐Chao Chen; Guo‐Hua Liu; Ming Xu; Pei‐Li Shi; Fei Peng; Atsushi Tsunekawa; Yu Liu; Xiao‐Dan Wang; Shi‐Kui Dong; et al. (Global Ecology and Biogeography, 2020)
Aim Climate change is expected to have important effects on plant phenology and carbon storage, with further shifts predicted in the future. Therefore, we proposed the community carbon accumulation rate (CAR) from the start of the growing season (SOS) to the peak of the growing season (POS) to fill the gap that the dynamic interactions between plant phenology and plant carbon research. Location Tibetan Plateau. Major taxa Alpine grassland plants. Time period 2015. Methods We conducted a transect survey across grasslands to measure community aboveground net primary production and carbon concentration. Additionally, phenology indicator data (SOS and POS) were extracted from the Global Inventory Modeling and Mapping Studies (GIMMS) normalized difference vegetation index version 3 database. Next, we used ‘ changepoint ’ analysis to detect the patterns of CARs, and performed linear regression and one‐way ANOVA to explore the variability of CARs in response to the environmental factors. Ultimately, the total effects of environmental factors on CARs were illustrated by a structural equation model. Results Our results indicated that three CAR patterns were detected, which are low‐CAR (0.15 g/m 2 /day), medium‐CAR (0.31 g/m 2 /day) and high‐CAR (0.84 g/m 2 /day) patterns. We found that the availabilities of water and heat mediated CARs by regulating soil nutrition variability, and that drought climate and insufficient soil resources co‐constrained the community CAR at long time‐scales. In contrast, high CAR could be explained by more water and heat availability via either direct or indirect effects on soil moisture and soil nutrients. Main conclusions Our findings highlight that water and heat availability are critical driving factors in ecological carbon accumulation processes undergoing climate change. Meanwhile, the vegetative phenology also has important effect on carbon accumulation. Consequently, we propose incorporating the dynamic interactions between plant phenology and plant carbon into the ecological carbon cycle model to improve our understanding of resource utilization and survival strategies of plants under environmental change.

Sikokianin A from Wikstroemia indica protects PC12 cells against OGD/R-induced injury via inhibiting oxidative stress and activating Nrf2 - Huankai Yao; Wenting Zhang; Huiling Wu; Ming Yang; Pengxiang Wei; Hang Ma; Jingyu Duan; Chunping Zhang; Yan Li (Natural Product Research, 2019)

Quantitative Tortuosity Measurements of Carbonate Rocks Using Pulsed Field Gradient NMR - Kaishuo Yang; Ming Li; Nicholas N. A. Ling; Eric F. May; Paul R. J. Connolly; Lionel Esteban; Michael B. Clennell; Mohamed Mahmoud; Ammar El-Husseiny; Abdulrauf R. Adebayo; Mahmoud Mohamed Elsayed; Michael L. Johns (Transport in Porous Media, 2019)

Effects of Exogenous GA3 and DPC Treatments on Levels of Endogenous Hormone and Expression of Key Gibberellin Biosynthesis Pathway Genes During Stem Elongation in Sugarcane - Li-Hang Qiu; Rong-Fa Chen; Han-Min Luo; Ye-Geng Fan; Xing Huang; Jun-Xian Liu; Fa-Qian Xiong; Hui-Wen Zhou; Chong-Kun Gan; Jian-Ming Wu; Yang-Rui Li (Sugar Tech, 2019)

Involvement of Interferon Regulatory Factor 7 in Nicotine’s Suppression of Antiviral Immune Responses - Haijun Han; Wenfei Huang; Wenjuan Du; Quan Shen; Zhongli Yang; Ming D. Li; Sulie L. Chang (Journal of Neuroimmune Pharmacology, 2019)

Flexible options to provide energy for capturing carbon dioxide in coal-fired power plants under the Clean Development Mechanism - Jiaquan Li; Zhifu Mi; Yi-Ming Wei; Jingli Fan; Yang Yang; Yunbing Hou (Mitigation and Adaptation Strategies for Global Change, 2019)

Interception of sulfate deposition from a closed canopy to a forest gap edge canopy in a subalpine dragon spruce plantation - Yu Zhang; Fu-zhong Wu; Bo Tan; Zhen-feng Xu; Han Li; Jun-cheng Liu; Hai-rong Zhao; Si-yi Tan; Cheng-ming You; Wan-qin Yang (Journal of Mountain Science, 2019)

Molecular identification and phylogenetic relationships of clinical Nocardia isolates - Ming Wei; Peng Wang; Chunxia Yang; Li Gu (Antonie van Leeuwenhoek, 2019)

Fine mapping and candidate gene analysis of a QTL associated with leaf rolling index on chromosome 4 of maize (Zea mays L.) - Lulu Gao; Guanghui Yang; Yufeng Li; Nannan Fan; Hongjian Li; Ming Zhang; Ruibin Xu; Mingyi Zhang; Aiju Zhao; Zhongfu Ni; Yirong Zhang (Theoretical and Applied Genetics, 2019)

Major advances in studies of the physical geography and living environment of China during the past 70 years and future prospects - Fahu Chen; Bojie Fu; Jun Xia; Duo Wu; Shaohong Wu; Yili Zhang; Hang Sun; Yu Liu; Xiaomin Fang; Boqiang Qin; Xin Li; Tingjun Zhang; et al. (Science China Earth Sciences, 2019)

Microencapsulated β-carotene preparation using different drying treatments - Xiang-yu Li; Mian-bin Wu; Min Xiao; Shu-huan Lu; Zhi-ming Wang; Jian-ming Yao; Li-rong Yang (Journal of Zhejiang University-SCIENCE B, 2019)

Ablation of serum response factor in hepatic stellate cells attenuates liver fibrosis - Ming Kong; Wenxuan Hong; Yang Shao; Fangqiao Lv; Zhiwen Fan; Ping Li; Yong Xu; Junli Guo (Journal of Molecular Medicine, 2019)

Protective role of curcumin in cadmium-induced testicular injury in mice by attenuating oxidative stress via Nrf2/ARE pathway - Shu-Hua Yang; Jian-Bin He; Li-Hui Yu; Lin Li; Miao Long; Ming-Da Liu; Peng Li (Environmental Science and Pollution Research, 2019)

Isolation, purification and identification of two new alkaloids metabolites from marine-derived Verrucosispora sp. FIM06025 - Ming-Hong Chen; Wen-Long Zhang; Li Chen; Ru Lin; Yang Xie; Dong-Sheng Fang; Yun-Yang Lian; Hong Jiang (Natural Product Research, 2019)

Two-factor ANOVA of SSH and RNA-seq analysis reveal development-associated Pi-starvation genes in oilseed rape - Zhong-Wei Zhang; Ling-Yang Feng; Jian-Hui Wang; Yu-Fan Fu; Xin Cai; Chang-Quan Wang; Jun-Bo Du; Ming Yuan; Yang-Er Chen; Pei-Zhou Xu; Ting Lan; Guang-Deng Chen; et al. (Planta, 2019)

Use of thermal imaging and Fourier transform infrared spectroscopy for the pre-symptomatic detection of cucumber downy mildew - Dong-Mei Wen; Mei-Xiang Chen; Li Zhao; Tao Ji; Ming Li; Xin-Ting Yang (European Journal of Plant Pathology, 2019)

Conflict between wild boars (Sus scrofa) and farmers: distribution, impacts, and suggestions for management of wild boars in the Three Gorges Reservoir Area - Qin Liu; Kun Yan; Ya-feng Lu; Ming Li; Yang-yang Yan (Journal of Mountain Science, 2019)

Assessing the influence of the minimum measured diameter on forest spatial patterns and nearest neighborhood relationships - Yuan-fa Li; Hai-peng Yang; Hong-xiang Wang; Shao-ming Ye; Wen-zhen Liu (Journal of Mountain Science, 2019)

Ottowia flava sp. nov., isolated from fish intestines - Song-Biao Shi; Gui-Ding Li; Li-Fang Yang; Cong Liu; Ming-Guo Jiang; Qin-Yuan Li; Jia-Fa Wu; Kun Zhang; Long-Qian Jiang; Nai-Kun Shen; Cheng-Lin Jiang; Yi Jiang (Antonie van Leeuwenhoek, 2019)

Paeoniflorin attenuates impairment of spatial learning and hippocampal long-term potentiation in mice subjected to chronic unpredictable mild stress - Si-Cheng Liu; Wei-Yan Hu; Wei-Yuan Zhang; Lu Yang; Yan Li; Zhi-Cheng Xiao; Ming Zhang; Zhi-Yong He (Psychopharmacology, 2019)

Detection and attribution of upper-tropospheric warming over the tropical western Pacific - Yana Li; Song Yang; Yi Deng; Xiaoming Hu; Ming Cai; Wen Zhou (Climate Dynamics, 2019)

Advances in plant GDSL lipases: from sequences to functional mechanisms - Li-Na Ding; Ming Li; Wei-Jie Wang; Jun Cao; Zheng Wang; Ke-Ming Zhu; Yan-Hua Yang; Yu-Long Li; Xiao-Li Tan (Acta Physiologiae Plantarum, 2019)

A breeding strategy targeting the secondary gene pool of bread wheat: introgression from a synthetic hexaploid wheat - Ming Hao; Lianquan Zhang; Laibin Zhao; Shoufen Dai; Aili Li; Wuyun Yang; Die Xie; Qingcheng Li; Shunzong Ning; Zehong Yan; Bihua Wu; Xiujin Lan; et al. (Theoretical and Applied Genetics, 2019)

Three BnaIAA7 homologs are involved in auxin/brassinosteroid-mediated plant morphogenesis in rapeseed (Brassica napus L.) - Ming Zheng; Maolong Hu; Hongli Yang; Min Tang; Liang Zhang; Hongfang Liu; Xiaokang Li; Jinglin Liu; Xingchao Sun; Shihang Fan; Jiefu Zhang; William Terzaghi; et al. (Plant Cell Reports, 2019)

The peculiar physiological responses of Rhizoctonia solani under the antagonistic interaction coupled by a novel antifungalmycin N2 from Streptomyces sp. N2 - Yong Yang; Zhi-ming Wu; Kun-tai Li (Archives of Microbiology, 2019)

Two new sesquiterpenes from cultures of the higher fungus Pholiota nameko - Xiao-Yan Yang; Wan-Rong Niu; Rui-Ting Li; Xiu-Ming Cui; Ji-Kai Liu (Natural Product Research, 2019)

A slab break-off model for mafic–ultramafic igneous complexes in the East Kunlun Orogenic Belt, northern Tibet: insights from early Palaeozoic accretion related to post-collisional magmatism - Jia-ming Yan; Feng-yue Sun; Liang Li; Yan-qian Yang; De-xin Zhang (International Geology Review, 2019)

Dynamics of maize straw–derived nitrogen in soil aggregates as affected by fertilization - Yang Wang; Ming Li; Jiubo Pei; Tingting An; Muhammad Farhan Saeed; Te Shan; Yingde Xu; Jingkuan Wang (Journal of Soils and Sediments, 2019)

Role of Maize Root Exudates in Promotion of Colonization of Bacillus velezensis Strain S3-1 in Rhizosphere Soil and Root Tissue - Yeqing Jin; Hangfei Zhu; Si Luo; Wenwu Yang; Li Zhang; Shanshan Li; Qing Jin; Qin Cao; Shurong Sun; Ming Xiao (Current Microbiology, 2019)

Complex rock slope deformation at Laxiwa Hydropower Station, China: background, characterization, and mechanism - Min Xia; Guang Ming Ren; Tian Bin Li; Ming Cai; Tian Jun Yang; Zong Li Wan (Bulletin of Engineering Geology and the Environment, 2019)

Strain identification and metabolites isolation of Aspergillus capensis CanS-34A from Brassica napus - Jing Qin; Ang Lyu; Qing-hua Zhang; Long Yang; Jing Zhang; Ming-de Wu; Guo-qing Li (Molecular Biology Reports, 2019)

Trend analysis and modeling of nutrient concentrations in a preliminary eutrophic lake in China - Xinnan Tong; Xinze Wang; Zekun Li; Pingping Yang; Ming Zhao; Kaiqin Xu (Environmental Monitoring and Assessment, 2019)

Multi-scale temporal-spatial variability of the East Asian summer monsoon frontal system: observation versus its representation in the GFDL HiRAM - Yana Li; Yi Deng; Song Yang; Henian Zhang; Yi Ming; Zhaoyi Shen (Climate Dynamics, 2019)