Superior Fenton-like and photo-Fenton-like activity of MoS2@TiO2/N-doped carbon nanofibers with phase-regulated and vertically grown MoS2 nanosheets - Yue Li; Bo Yu; Bo Liu; Xiang Yu; Gang Qin; Menghao Fan; Yongcai Zhang; Longlu Wang (Chemical Engineering Journal, 2023)

Design and efficacy of all-in-one sandwich-like multifunctional platform for drug delivery - Bo Zhang; Yumei Qin; Yanyan Li; Yu Wang; Huining Wan; Xiyu Liu; Xiaoqin Hu; Yongqi An; Hao Zhang; Li Yang; Rifang Luo; Yunbing Wang (Chemical Engineering Journal, 2023)

Biomimetic niche of vascular intima with biophysical orientation and biochemical stimulation for rapid endothelialization and long-term patency - Zihao Wang; Mengyu Li; Bin Wang; Yin Xu; Jinyu Li; Shengmin Zhang; Qinghua Qin; Jianglin Wang (Chemical Engineering Journal, 2023)

Temperature tolerant all-solid-state touch panel with high stretchablity, transparency and self-healing ability - Zhenglin Chen; Fang Li; Likun Zhang; Zhengyang Lei; Canhui Yang; Chufan Xiao; Lijin Lian; Xi Yuan; Gul Ijaz; Jia'e Yang; Zijun Lin; Yunfeng He; et al. (Chemical Engineering Journal, 2023)

Ni(OH)2 clusters decorated NiTiO3 Z-scheme heterojunctions with strong O2 activation and robust interfacial built-in electric field for efficient NO photo-oxidation - Guojun Li; Zheng Lian; Zhengwei Wan; Zhinian Liu; Jingwen Qian; Yue Deng; Shule Zhang; Qin Zhong (Chemical Engineering Journal, 2023)

Anionic metal-organic framework modified separator boosting efficient Li-ion transport - Jiaqi Li; Long Chen; Fengling Wang; Zuoyu Qin; Ying Zhang; Ning Zhang; Xiaohe Liu; Gen Chen (Chemical Engineering Journal, 2023)

In-situ etching and ion exchange induced 2D-2D MXene@Co9S8/CoMo2S4 heterostructure for superior Na+ storage - Mengqi Wang; Xinlong Liu; Binyang Qin; Zhiyong Li; Yufei Zhang; Wei Yang; Haosen Fan (Chemical Engineering Journal, 2023)

Low concentrations of benzophenone-type UV-filters impair testis development in the amphibian Xenopus laevis - Hong-Mei Li; Ying-Chi Zhang; Yuan-Yuan Li; Qing-Qing Zhu; Jie Li; Hai-Ming Xu; Yi-Ming Xiong; Zhan-Fen Qin (Aquatic Toxicology, 2023)

Nattokinase enhances the preventive effects of Escherichia coli Nissle 1917 on dextran sulfate sodium-induced colitis in mice - Manyu Liang; Jing Zhang; Yanhong Yang; Yi Xia; Lintao Liu; Li Liu; Qin Wang; Xiaowei Gao (World Journal of Microbiology and Biotechnology, 2023)

Fine mapping and cloning of a novel BrSCC1 gene for seed coat color in Brassica rapa L - Yinghuan Zhang; Yao Qin; Dongxiao Li; Wei Wang; Xu Gao; Chunming Hao; Hui Feng; Yugang Wang; Tianlai Li (Theoretical and Applied Genetics, 2023)

The genomic, transcriptomic, and immunological profiles of perineural invasion in pancreatic ductal adenocarcinoma - Shu-Heng Jiang; Rong-Kun Li; De-Jun Liu; Jun-Li Xue; Min-Hao Yu; Shan Zhang; Li-Min Liu; Jun-Feng Zhang; Rong Hua; Yong-Wei Sun; Xu Wang; Qin Yang; et al. (Science China Life Sciences, 2023)

Combined wind profile characteristics based on wind parameters joint probability model in a mountainous gorge - Mingjin Zhang; Jinxiang Zhang; Fanying Jiang; Lianhuo Wu; Jingxi Qin; Yongle Li (Natural Hazards, 2023)

PGC-1α participates in tumor chemoresistance by regulating glucose metabolism and mitochondrial function - Yanqing Li; Hu Hei; Songtao Zhang; Wenbo Gong; Yann Liu; Jianwu Qin (Molecular and Cellular Biochemistry, 2023)

Functional characterization of powdery mildew resistance-related genes HbSGT1a and HbSGT1b in Hevea brasiliensis Muell. Arg. - Meng Wang; Huaxing Xiao; Xiaona Li; Sanlian Wan; Ye Yang; Haiyang Yu; Yu Zhang; Bi Qin (European Journal of Plant Pathology, 2023)

Spatial distribution and quantitative source identification of nutrients and beneficial elements in the soil of a typical suburban area, Beijing - Qin-Rui Zhang; Sheng-Qiang Zhang; Yong Huang; Huan Li; Yan-Hui Jia; Jun Li; Guo-Li Yuan (Environmental Monitoring and Assessment, 2023)

Geographical, Sex, Age, and Seasonal Differences in Serum Manganese Status Among Chinese Adults with Hypertension - Hong Chen; Zhixin Cui; Wenhai Lu; Ping Wang; Jia Wang; Ziyi Zhou; Nan Zhang; Zhuo Wang; Tengfei Lin; Yun Song; Lishun Liu; Xiao Huang; et al. (Biological Trace Element Research, 2023)

Flow distribution in the air cooler of HTGR passive cavity cooling system - Haiqi Qin; Xiaowei Li; Li Zhang; Xinxin Wu (Annals of Nuclear Energy, 2023)

A dual-responsive fluorescent turn-on sensor for sensitively detecting and bioimaging of hydrazine and hypochlorite in biofluids, live-cells, and plants - Ruiming Chen; Tingting Hu; Shu Xing; Tao Wei; Jianbin Chen; Tianduo Li; Qingfen Niu; Zhengyang Zhang; Huijun Ren; Xiaoxu Qin (Analytica Chimica Acta, 2023)

Longitudinal expression profiles of flavonoid synthesis-related genes and their correlations with contents of flavonoids including anthocyanins in purplish-green aerial stems of Panax notoginseng - Hongling Zhang; Guiqiong Li; Min Jiang; Changling Zhao; Pengyu Zhao; Chen Wang; Guosong Wen; Feng Zhou; Wenhua Dongchen; Shaozhong Xu; Ting Mu; Fanlai Meng; et al. (Acta Physiologiae Plantarum, 2023)

Evaluation of ERA5 , ERA‐Interim , JRA55 and MERRA2 reanalysis precipitation datasets over the Poyang Lake Basin in China - Xiangxiang Li; Xiaochen Qin; Jun Yang; Yizhi Zhang (International Journal of Climatology, 2022)
Increasing variability of precipitation induced by climate change raises uncertainties for ecosystem services and agricultural production in the Poyang Lake Basin (PLB), China. Reanalysis precipitation datasets (RPDs) are attractive alternatives for monitoring the hydro‐climate cycles. However, their applicability in China has mainly been evaluated at the national scale, while less attention has been paid to the PLB or southeastern China. Here, we apply various metrics to evaluate the magnitude and spatial similarity of annual, monthly, different intensities and the spatial structure of precipitation from four reanalysis—the fifth global atmospheric analysis dataset of the European Center for Medium‐Range Weather Forecasts (ECMWF) (ERA5), Interim ECMWF Reanalysis (ERA‐Interim), Japanese 55‐year Reanalysis project (JRA55) and Modern‐Era Retrospective analysis for Research and Applications, Version 2 (MERRA‐2), against the rain‐gauges over the PLB during 1980–2018. The results showed that the detection capacity of ERA5 and MERRA2 shifted around 2002, whereas that of ERA‐Interim and JRA55 did not substantially change. Before 2002, ERA‐Interim had the lowest biases for the magnitude of annual, monthly and different intensities of precipitation (except for heavy rain), while ERA5 and MERRA2 had strengths in capturing spatial correlation. Notably, ERA5 and MERRA2 had region‐wide wet and dry biases, respectively, before 2002, which can be attributed mainly to the estimation of flood season precipitation (from April to June) and heavy rain. In contrast, the fractional contribution of light–moderate rain was underestimated and overestimated by ERA5 and MERRA2, respectively. However, after 2002, because of the improved reproducibility of flood season precipitation and heavy rain magnitude, the systematic biases of ERA5 and MERRA2 significantly decreased, especially for ERA5, which outperformed other RPDs on all aspects of precipitation. The conclusions of this paper suggest that the variation of applicability over time should be seriously tested before the utilization of RPDs in hydro‐climate analyses.

Effect and Mechanism of Cotrimoxazole Against Talaromyces marneffei in vitro - Jie Chen; Rongfeng Chen; Wudi Wei; Fengxiang Qin; Xiu Chen; Jinhao He; Hong Zhang; Gang Wang; Minjuan Shi; Tongxue Qin; Yinlu Liao; Yuting Wu; et al. (Mycopathologia, 2022)

Periodic phosphorus fertilization is beneficial to lowering potential risk of phosphorus loss from Inceptisols - Yongzhuang Wang; Liuying Lai; Xiangying Peng; Hongxing Chen; Joann K. Whalen; Caiyan Lu; Dan Li; Xinying Zhang; Lingling Qin; Xin Chen; Lingtian Xie (Journal of Soils and Sediments, 2022)

Phosphorus Fertigation Conferred Lodging Tolerance and Improved Grain Quality in Chenopodium quinoa via Enhanced Root Proliferation and Stalk Strength - Yan Deng; Li Zhao; Sumera Anwar; Li-Guang Zhang; Fahad Shafiq; Hong-Xia Guo; Li-Xia Qin; Mei-Xia Wang; Chuang-Yun Wang (Journal of Soil Science and Plant Nutrition, 2022)

An association study on the risk, glucocorticoids effectiveness, and prognosis of systemic lupus erythematosus: insight from mitochondrial DNA copy number - Zhen Li; Qi-Qun Zong; Chun-Xia Zhai; Guang-Hui Yu; Wan-Qin Hu; Yu-Hua Wang; Lin-Lin Wang; Zi-Ye Yan; Ting-Yu Zhang; Ying Teng; Shuang Liu; Jing Cai; et al. (Immunologic Research, 2022)

Study on prediction in far-field aerodynamic noise of long-marshalling high-speed train - Deng Qin; Tian Li; Zhiyuan Dai; Jiye Zhang (Environmental Science and Pollution Research, 2022)

Effects of STAT3 Inhibitor BP-1-102 on The Proliferation, Invasiveness, Apoptosis and Neurosphere Formation of Glioma Cells in Vitro - Cheng-Chen Zhang; Ting Wu; Li Guan; Yu-Jue Wang; Rui-Qin Yao; Dian-Shuai Gao; Feng Li (Cell Biochemistry and Biophysics, 2022)

Escherichia coli phage phi2013: genomic analysis and receptor identification - Donghang Li; Zhiqiang Zhang; Yueying Li; Xixi Zhang; Xuying Qin; Dongsheng Wei; Hongjiang Yang (Archives of Virology, 2022)

Longitude correction method for the field magnetic surveyed diurnal-variation correction - Shu-Peng Su; Bo Li; Hai-Yang Zhang; Hui-Qin Zhao; Jin-Peng Huang (Applied Geophysics, 2022)

Abundant and diverse endophytic bacteria associated with medicinal plant Arctium lappa L. and their potential for host plant growth promoting - Jia-Qi Liu; Shu-Mei Chen; Chun-Mei Zhang; Ming-Jie Xu; Ke Xing; Cheng-Guo Li; Kui Li; Yu-Qin Zhang; Sheng Qin (Antonie van Leeuwenhoek, 2022)

The cAMP‐PKA signalling pathway regulates hyphal growth, conidiation, trap morphogenesis, stress tolerance, and autophagy in Arthrobotrys oligospora - Mei‐Chen Zhu; Na Zhao; Yan‐Kun Liu; Xue‐Mei Li; Zheng‐Yi Zhen; Ya‐Qing Zheng; Ke‐Qin Zhang; Jin‐Kui Yang (Environmental Microbiology, 2022)
The cyclic adenosine monophosphate‐protein kinase A (cAMP‐PKA) signalling pathway is evolutionarily conserved in eukaryotes and plays a crucial role in defending against external environmental challenges, which can modulate the cellular response to external stimuli. Arthrobotrys oligospora is a typical nematode‐trapping fungus that specializes in adhesive networks to kill nematodes. To elucidate the biological roles of the cAMP‐PKA signalling pathway, we characterized the orthologous adenylate cyclase AoAcy, a regulatory subunit (AoPkaR), and two catalytic subunits (AoPkaC1 and AoPkaC2) of PKA in A. oligospora by gene disruption, transcriptome, and metabolome analyses. Deletion of Aoacy significantly reduced the levels of cAMP and arthrobotrisins. Results revealed that Aoacy , AopkaR , and AopkaC1 were involved in hyphal growth, trap morphogenesis, sporulation, stress resistance, and autophagy. In addition, Aoacy and AopkaC1 were involved in the regulation of mitochondrial morphology, thereby affecting energy metabolism, whereas AopkaC2 affected sporulation, nuclei, and autophagy. Multi‐omics results showed that the cAMP‐PKA signalling pathway regulated multiple metabolic and cellular processes. Collectively, these data highlight the indispensable role of cAMP‐PKA signalling pathway in the growth, development, and pathogenicity of A. oligospora, and provide insights into the regulatory mechanisms of signalling pathways in sporulation, trap formation, and lifestyle transition.

Effects of coexposure to noise and mixture of toluene, ethylbenzene, xylene, and styrene (TEXS) on hearing loss in petrochemical workers of southern China - Yan Zhang; Yan Liu; Zongxin Li; Xin Liu; Qingfei Chen; Jingyao Qin; Qilong Liao; Rui Du; Qifei Deng; Yongmei Xiao; Xiumei Xing (Environmental Science and Pollution Research, 2022)

The Responses of the Ovary and Eyestalk in Exopalaemon carinicauda under Low Salinity Stress - Xiuhong Zhang; Jiajia Wang; Chengwei Wang; Wenyang Li; Qianqian Ge; Zhen Qin; Jian Li; Jitao Li (Fishes, 2022)
As a euryhaline shrimp, the ridgetail white prawn Exopalaemon carinicauda is strongly adaptable to salinity. Exploring the effect of long-term low salinity stress on ovarian development in E. carinicauda is essential to promote its culture in a non-marine environment. In this study, we performed biochemical assays and ovary histology analysis, finding that the E. carinicauda can adapt to low salinity stress through osmotic adjustment, and there was no substantial damage to the ovary of E. carinicauda under low salinity stress. Then, the ovarian development of E. carinicauda under low salt stress was further explored by RNA sequencing of eyestalk and ovarian tissues. A total of 389 differentially expressed genes (DEGs) in ovary tissue were identified under low salinity stress, and the 16 important DEGs were associated with ovarian development. The majority of the DEGs were enriched in ECM-receptor interaction, folate biosynthesis, arginine biosynthesis, insect hormone biosynthesis and lysosome which were involved in the ovarian development of E. carinicauda. A total of 1223 DEGs were identified in eyestalk tissue under low salinity stress, and the 18 important DEGs were associated with ovarian development. KEGG enrichment analysis found that ECM-receptor interaction, folate biosynthesis, lysosome, arginine biosynthesis and retinol metabolism may be involved in the ovarian development under low salinity stress. Our results provided new insights and revealed new genes and pathways involved in ovarian development of E. carinicauda under long-term low salinity stress.

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression - Qin Jin; Xiaoyu Yang; Shixue Gou; Xiaoyi Liu; Zhenpeng Zhuang; Yanhui Liang; Hui Shi; Jiayuan Huang; Han Wu; Yu Zhao; Zhen Ouyang; Quanjun Zhang; et al. (Science China Life Sciences, 2022)

Investigation of microplastic pollution on paddy fields in Xiangtan City, Southern China - Yudi Wang; Wenjie Cui; Zhenghua Duan; Li Qin; Haihong Zhang; Haodong Cheng; Lei Wang (Environmental Science and Pollution Research, 2022)

Hydrogeochemical characterization and water quality assessment in Altay, Xinjiang, northwest China - Juan-Qin Gao; Yang Yu; Deng-Hong Wang; Li-Jun Liu; Wei Wang; Hong-Zhang Dai; Kuang Cen (Environmental Monitoring and Assessment, 2022)

Concentrations, distribution, and risk assessment of endosulfan residues in the cotton fields of northern Xinjiang, China - Yang Zhang; Rong Guo; Yang Li; Mingyu Qin; Jingquan Zhu; Zhihong Ma; Yong Ren (Environmental Geochemistry and Health, 2022)

Salinimicrobium sediminilitoris sp. nov., Isolated from a Tidal Flat - Cheng-Qiang Xia; Hui-Jing Niu; Kai-Shi Dong; Li Guan; Li-Ping Sun; Qin Wang; Yan-Jiao Zhang; Yi Li; Cai-Xia Pei (Current Microbiology, 2022)

Altered Resting State Networks Before and After Temporal Lobe Epilepsy Surgery - Wei Li; Yuchao Jiang; Yingjie Qin; Xiuli Li; Du Lei; Heng Zhang; Ding Lei; Dezhong Yao; Cheng Luo; Qiyong Gong; Dong Zhou; Dongmei An (Brain Topography, 2022)

PDGFD switches on stem cell endothelial commitment - Weisi Lu; Peipei Xu; Boxiong Deng; Jianing Zhang; Ying Zhan; Xianchai Lin; Xiangzhong Xu; Zhaoxia Xia; Xiaoxi Yang; Xiaoling Zeng; Lijuan Huang; Bingbing Xie; et al. (Angiogenesis, 2022)
The critical factors regulating stem cell endothelial commitment and renewal remain not well understood. Here, using loss- and gain-of-function assays together with bioinformatic analysis and multiple model systems, we show that PDGFD is an essential factor that switches on endothelial commitment of embryonic stem cells (ESCs). PDGFD genetic deletion or knockdown inhibits ESC differentiation into EC lineage and increases ESC self-renewal, and PDGFD overexpression activates ESC differentiation towards ECs. RNA sequencing reveals a critical requirement of PDGFD for the expression of vascular-differentiation related genes in ESCs. Importantly, PDGFD genetic deletion or knockdown increases ESC self-renewal and decreases blood vessel densities in both embryonic and neonatal mice and in teratomas. Mechanistically, we reveal that PDGFD fulfills this function via the MAPK/ERK pathway. Our findings provide new insight of PDGFD as a novel regulator of ESC fate determination, and suggest therapeutic implications of modulating PDGFD activity in stem cell therapy.

Overexpression of the maize phytochelatin synthase gene (ZmPCS1) enhances Cd tolerance in plants - Demiao Jin; Qin Zhang; Yuqing Liu; Mengna Liang; Aiqi Li; Jiandong Wu (Acta Physiologiae Plantarum, 2022)

Extreme temperatures and circulatory mortality in a temperate continental monsoon climate city in Northeast China - Yuxia Ma; Heping Li; Pengpeng Qin; Bowen Cheng; Fengliu Feng; Yifan Zhang; Haoran Jiao (Environmental Science and Pollution Research, 2022)

Molecular phylogeny and divergence time estimates for native giant clams (Cardiidae: Tridacninae) in the Asia-Pacific: Evidence from mitochondrial genomes and nuclear 18S rRNA genes - Haitao Ma; Dongmei Yu; Jun Li; Yanping Qin; Yang Zhang; Zhiming Xiang; Yuehuan Zhang; Ziniu Yu (Frontiers in Marine Science, 2022)
Giant clams are conspicuous bivalves that inhabit in coral reefs. Among the giant clams, eight species of subfamily Tridacninae are the most common in the Asia-Pacific. However, very little is known about their evolutionary history. Here, we determined the complete mitochondria genome of Hippopus porcellanus , which was 29,434 bp in size and contained 13 protein-coding genes, 2 rRNAs and 23 tRNAs. The A+T composition of protein-coding regions was 57.99%, and the AT composition of the 3 rd codon position was 59.33%, of which in agreement with the invertebrate bias favoring codons ending in A or T. Analysis of phylogenetic relationships according to the concatenated nucleotide data set containing 18S rRNA gene and 13 protein-coding genes, the phylogenetic relationship was analyzed by Maximum likelihood and Bayesian inference methods. The results showed that T. maxima was placed with the clade comprising T. noae , T. squamosa , and T. crocea , in which T. squamosa was highly similar to T. crocea and is consistent with the results of the previous studies using15 mitochondrial markers and nuclear 18S rRNA. Moreover, the inferred divergence time of Tridacnidae species is generally consistent with the fossil record of Tridacnidae. The divergence time of H. porcellanus and H. hippopus was about 10.64 Mya, this result is in agreement with the speculation that H. porcellanus also originated in Miocene. The availability of molecular phylogeny and divergence time estimation provides information genetic relationship of Tridacninae, which could be helpful to the ecological research and conservation of giant clams.

Effects of initial particle sizes of Triarrhena lutarioriparia on processing performance, material properties, and heavy metal speciation in sewage sludge composting - Min Ruan; Yanru Zhang; Xikai Wu; Yutong Sun; Zhongliang Huang; Hui Li; Zhangmao Hu; Zijian Wu; Xuan Zhang; Xiaoli Qin; Jing Huang (Environmental Science and Pollution Research, 2022)

Variation in the attached community structure and function of artificial habitats during ecological succession: A case study of the artificial reef area in Bailong Pearl Bay, China - Ruolin Li; Yu Guo; Ankai Zhang; Shuo Zhang; Hui Zhang; Chuanxin Qin (Frontiers in Marine Science, 2022)
With the continuous development of ports, ship transportation, resource extraction and artificial habitat deployment, an increasing number of artificial structures have created new usable spaces for marine organisms, and the biological communities living on their surfaces have undergone ecological succession. However, related studies have ignored ecological functions, interspecific relationships, and stability in different successional stages. Based on traditional taxonomy, this study applied functional diversity, niche overlap and niche breadth indexes to compare the attached organisms on artificial reefs (ARs) with different construction times in Bailong Pearl Bay, Fangchenggang City, Guangxi Zhuang Autonomous Region, China. The change trends of richness, habitat resource supply, resource utilization degree and efficiency, and interspecific relationships during the succession process were analysed. The results indicated that richness increased with functional diversity. While the number of species increased, the attached organisms showed different functional characteristics, and the number of species with identical traits decreased. The attached community in the later stage of development had a higher degree of utilization of ecological space, more comprehensive and efficient utilization of effective resources, a stronger degree of complementarity of organismal niches, and weaker interspecific competition. In the early stage of the developmental process, the attached community was affected by more environmental factors and had very significant correlations with those factors. The combination of the niche overlap index and the niche breadth index indicated that the resource supply supporting the survival and development of the attached organisms on the ARs with earlier construction times may be greater. The decrease in the number of biomarkers, the similarity of biomarkers belonging to the same family, and the similarity of dominance alternation all indicated that during the process of long-term development and community succession, the organisms attached to the various parts of the ARs tended to become more similar.

MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin - Xiangyu Zhang; Lijun Chen; Xingnan Huang; Huan Chen; Baomei Cai; Yue Qin; Yating Chen; Sihua Ou; Xiaoxi Li; Zichao Wu; Ziyu Feng; Mengying Zeng; et al. (Stem Cell Reviews and Reports, 2022)

Carbon sequestration in soil and biomass under native and non-native mangrove ecosystems - Ziming Zhang; Ying Wang; Yakun Zhu; Kehong He; Tingting Li; Umakant Mishra; Yisheng Peng; Fan Wang; Lingfei Yu; Xiaosong Zhao; Liye Zhu; Xudong Zhu; et al. (Plant and Soil, 2022)

Comparative Transcriptome Analysis Reveals Potential Gene Modules Associated with Cold Tolerance in Sugarcane (Saccharum officinarum L.) - Xing Huang; Yongsheng Liang; Baoqing Zhang; Xiupeng Song; Yangrui Li; Changning Li; Zhengqiang Qin; Dewei Li; Jiguang Wei; Jianming Wu (Journal of Plant Growth Regulation, 2022)
Sugarcane is an important crop worldwide, and most sugar is derived directly from sugarcane. Due to its thermophilic nature, the yield of sugarcane is largely influenced by extreme climate conditions, especially cold stress. Therefore, the development of sugarcane with improved cold tolerance is an important goal. However, little is known about the multiple mechanisms underlying cold acclimation at the bud stage in sugarcane. In this study, we emphasized that sensitivity to cold stress was higher for the sugarcane variety ROC22 than for GT42, as determined by physical signs, including bud growth capacity, relative conductivity, malonaldehyde contents, and soluble sugar contents. To understand the factors contributing to the difference in cold tolerance between ROC22 and GT42, comparative transcriptome analyses were performed. We found that genes involved in the regulation of the stability of the membrane system were the relative determinants of difference in cold tolerance. Additionally, genes related to protein kinase activity, starch metabolism, and calcium signal transduction were associated with cold tolerance. Finally, 25 candidate genes, including 23 variety-specific and 2 common genes, and 7 transcription factors were screened out for understanding the possible cold resistance mechanism. The findings of this study provide candidate gene resources for cold resistance and will improve our understanding of the regulation of cold tolerance at the bud stage in sugarcane.

Comparative transcriptome analyses identify genes involved into the biosynthesis of forsythin and forsythoside A in Forsythia suspensa - Wang Jun Yuan; Su Ping Zhang; Zhi Yin He; Yan Xia He; She Qi He; Li Jun Liu; Xin Sun; Qin Li (Functional & Integrative Genomics, 2022)

Dietary supplementation of two indigenous Bacillus spp on the intestinal morphology, intestinal immune barrier and intestinal microbial diversity of Rhynchocypris lagowskii - Xin-yu Lei; Dong-ming Zhang; Qiu-ju Wang; Gui-qin Wang; Yue-hong Li; Yu-rou Zhang; Men-nan Yu; Qi Yao; Yu-ke Chen; Zhi-xin Guo (Fish Physiology and Biochemistry, 2022)

Associations of urinary polycyclic aromatic hydrocarbon metabolites and blood pressure with the mediating role of cytokines: A panel study among children - Miao Liu; Lei Zhao; Linlin Liu; Wenting Guo; Huihua Yang; Jie Yu; Shuang Chen; Meng Li; Qin Fang; Xuefeng Lai; Liangle Yang; Rui Zhu; et al. (Environmental Science and Pollution Research, 2022)

Dynamic networks of P300-related process - Qin Tao; Lin Jiang; Fali Li; Yuan Qiu; Chanlin Yi; Yajing Si; Cunbo Li; Tao Zhang; Dezhong Yao; Peng Xu (Cognitive Neurodynamics, 2022)

The interaction between DOC released by cultured kelp (Saccharina japonica) and the bacterial community reveals the potential for increasing marine carbon sequestration by macroalgae culture - Mingliang Zhang; Huawei Qin; Zhidong Wang; Bin Li; Yuanqing Ma (Frontiers in Marine Science, 2022)
Macroalgae culture as a marine carbon sequestration strategy has been recently proposed. To understand the potential for carbon sequestration by macroalgae culture, we studied the interaction of dissolved organic carbon (DOC) released by Saccharina japonica , an important cultured kelp species in China, and the bacterial community. We found that S. japonica effectively released DOC containing both labile and refractory components, and the DOC released by S. japonica into the water decreased average molecular weight (Mass wa ) by 18 Da, meaning it was rich in low molecular weight matter. Degradation of labile DOC components occurred during the initial 2 months of the experiment. The Mass wa and molecular diversity of the DOC was increased in turn by bacterial degradation, and the variation in the DOC composition resulted in the succession of the bacterial community. During labile DOC degradation, anaerobic Gammaproteobacteria, Bacteroidia and Campylobacteria were the dominant microbial classes in the water, and aerobic Iodidimonadaceae became the dominant family during the final stage of the experiment. Finally, 5% of the DOC was transformed into refractory DOC. Although the sinking biomass was not involved in the study, the produced refractory DOC through the interaction between releasing DOC and bacterial degradation indicates a potential of carbon sequestration by macroalgae culture.

Transcriptome Analysis of Greenfin Horse-Faced Filefish (Thamnaconus septentrionalis) Gills in Response to Amyloodinium ocellatum (AO) Infection - Li-Guo Yang; Yue Wang; Wen-Bin Xu; Bo Qin; Na Ying; Xue-Feng Song; Yan-Feng Yue; Xiao-Shan Wang; Bian-Bian Zhang; Yan-Qing Wu (Fishes, 2022)
The greenfin horse-faced filefish (Thamnaconus septentrionalis) is susceptible to recurrent Amyloodinium ocellatum (AO) infestation over the grow-out production cycle. This parasite breeds mainly on the gills, causing hypoxia in the fish body, and leading to many deaths. The host-parasite response drives a complex immune reaction, which is poorly understood. To generate a model for host-parasite interaction and the pathogenesis of AO in greenfin horse-faced filefish, an RNA-seq approach, differential gene expression, GO, and KEGG analyses were employed. Overall, 624 new genes and 2076 differentially expressed genes (DEGs) were detected, including 942 upregulated and 1134 downregulated genes in the gills. Compared with the control group, the expression of leptin a, GTPase IMAP family member 4, and NLR family CARD domain-containing protein 3 was significantly higher in the AO-infected group. Conversely, cell wall integrity and stress response component 1-like, and hepcidin-like were significantly downregulated in the gills of AO-infected fish. GO and KEGG enrichment analysis indicated that DEGs were significantly enriched in signaling pathways associated with viral protein interaction with cytokine and cytokine receptor and cytokine–cytokine receptor interaction. Collectively, this transcriptomic study provides novel molecular insights into the pathology caused by AO infestation and alternative theories for future research implementing strategies to control and manage AO.

A urinary proteomic landscape of COVID-19 progression identifies signaling pathways and therapeutic options - Yuntao Liu; Lan Song; Nairen Zheng; Jinwen Shi; Hongxing Wu; Xing Yang; Nianci Xue; Xing Chen; Yimin Li; Changqing Sun; Cha Chen; Lijuan Tang; et al. (Science China Life Sciences, 2022)

Tidal water exchanges can shape the phytoplankton community structure and reduce the risk of harmful cyanobacterial blooms in a semi-closed lake - Wenxu Zheng; Renhui Li; Wenli Qin; Binbin Chen; Min Wang; Wanchun Guan; Xiaoling Zhang; Qiao Yang; Min Zhao; Zengling Ma (Journal of Oceanology and Limnology, 2022)

Competitiveness of alga Microcystis aeruginosa co-cultivated with cyanobacterium Raphidiopsis raciborskii confirms its dominating position - Zengling Ma; Xiaoqiao Zhang; Renhui Li; Min Wang; Wenli Qin; He Zhang; Gang Li; Henguo Yu; Chuanjun Dai; Min Zhao (Journal of Oceanology and Limnology, 2022)

Progress in urban resilience research and hotspot analysis: a global scientometric visualization analysis using CiteSpace - Yijun Liu; Qin Li; Wenlong Li; Yang Zhang; Xingwang Pei (Environmental Science and Pollution Research, 2022)

Preparation of Ni-La/Al2O3-CeO2-Bamboo Charcoal Catalyst and Its Application in Co-pyrolysis of Straw and Plastic for Hydrogen Production - Yiran Zhang; Jianfen Li; Bolin Li; Zeshan Li; Yun He; Zhenhua Qin; Rongyi Gao (BioEnergy Research, 2022)

Applicability of standard forward column/row recurrence equations for ALFs - Han-Wei Zhang; Hua Zhang; Xiao-Ling Li; Yong-Qin Yang (Applied Geophysics, 2022)

Fried-food consumption and risk of overweight/obesity, type 2 diabetes mellitus, and hypertension in adults: a meta-analysis of observational studies - Pei Qin; Dechen Liu; Xiaoyan Wu; Yunhong Zeng; Xizhuo Sun; Yanyan Zhang; Yang Li; Yuying Wu; Minghui Han; Ranran Qie; Shengbing Huang; Yang Zhao; et al. (Critical Reviews in Food Science and Nutrition, 2022)

Sensitive time-resolved fluoroimmunoassay for the quantitative detection of okadaic acid - Yuan Qin; Jiayu Li; Jiani Kuang; Sicheng Shen; Jingwen Jiang; Zhi Zhang; Chenhao Zhao; Xiumei Zhou; Biao Huang; Bingnan Han (Frontiers in Marine Science, 2022)
Okadaic acid (OA) is a biotoxin from marine microalgae and widely present in shellfish, which severely affects the seafood safety. Therefore, it is essential to establish a highly sensitive OA analysis and detection method. In this study, a new type of immunoassay technology was established on the basis of the competition method using time-resolved fluoroimmunoassay (TRFIA). OA-bovine serum albumin (OA-BSA) coated on a 96-well plate competes with OA standard or samples to bind OA antibodies. A rare-earth ion-labeled secondary antibody, which fluoresces strongly under the effect of the enhancement solution, was then added as a tracer for detection. The established linear range of OA detected by TRFIA was 2.49 × 10 -3 – 50 ng/ml, and the limit of detection was 2.49 × 10 -3 ng/ml. The average coefficients of variation from intra-assay and inter-assay batches were 3.34% and 5.87%, respectively, and the recovery rate was 93.04%–111.66%. The OA in shellfish samples was determined by TRFIA and high-performance liquid chromatography (HPLC), and the results showed a good correlation. This study established a TRFIA to detect OA, which has the characteristics of simplicity, sensitivity, precision, and high accuracy, far exceeding the EU or the US standards for the detection of shellfish toxins. It is expected to make proper contribution in marine biotoxin detection.

A Realistic and Integrated Model for Evaluating Offshore Oil Development - Rui Qiu; Zhuochao Li; Qin Zhang; Xin Yao; Shuyi Xie; Qi Liao; Bohong Wang (Journal of Marine Science and Engineering, 2022)
With the rising consumption of oil resources, major oil companies around the world have increasingly engaged in offshore oil exploration and development, and offshore oil resources have accounted for an increasing proportion. Offshore oil engineering projects are capital intensive, and the development of offshore oil fields faces a tough battle, especially in a period of low oil prices. Thus, a comprehensive evaluation model is highly needed to help assess economic benefits and provide meaningful and valuable information for operators and investors to make sensible decisions. This study firstly proposed a realistic and integrated evaluation model for offshore oil development based on actual historical project data. This evaluation model incorporated modules from the underwater system to the platform system and processes from oil reservoir extraction to oil, gas and water treatment. The uncertain parameters in the evaluation process are dealt with by sensitivity analysis and Monte Carlo simulation. The proposed model is applied to a typical offshore oil development project in Bohai Bay, China. The results reveal that the recovery factor and oil price have the greatest impact on the economic benefits. In the case of deterministic analysis, the breakeven oil price of the project is 40.59 USD/bbl. After considering the uncertainty of project parameters, the higher the oil price, the greater the probability of NPV > 0. When the oil price is higher than 70 USD/bbl, even with uncertain project parameters, the probability of NPV > 0 can still be as high as 97.39%.

Geochemical and palynological records of rapid climatic change from the early to late Aptian: evidence from the Jiaolai Basin, eastern China - X. X. Wang; X. Y. Zhang; W. X. Wang; S. J. Li; M. Qin (Australian Journal of Earth Sciences, 2022)

RNAi-Based Transcriptome Suggests Candidate Genes Regulated by ZxNHX1 to Affect The Salt Tolerance of Zygophyllum xanthoxylum - Hai-Shuang Liu; Xiao-Nong Guo; Wei-Wei Chai; Rui-Xin Zhang; Pei-Qin Li; Cui-Min Ma; Qing Ma; Suo-Min Wang (Journal of Plant Growth Regulation, 2022)

Runoff projections of the Qinling Mountains and their impact on water demand of Guanzhong region in Northwest China - Zhao-peng Zhang; Ke-qin Duan; Huan-cai Liu; Ya-li Meng; Rong Chen; Da-wei Li; Shuang-shuang Li (Journal of Mountain Science, 2022)

Study on the Mechanical Properties of Silty Clay Sediments with Nodular Hydrate Occurrence - Cheng Lu; Pengfei Xie; Hui Li; Xuhui Zhang; Xiaobing Lu; Bin Zhang; Ziqin Zhang; Xuwen Qin; Shuai Zhang; Hang Bian (Journal of Marine Science and Engineering, 2022)
Natural gas hydrates are a strategic energy resource in China. The China Geological Survey has discovered segregated hydrate mass formations under the seepage mechanism in the South China Sea through exploration, and gas hydrates occur in nodular, massive, and vein formations in silty clay sediment. Previous work has focused on the analysis of sediment mechanical properties with respect to the uniform distribution of natural gas hydrates in pore spaces, but the mechanical properties of hydrate-bearing sediments containing segregated hydrate masses are not well understood. Spherical hydrates are used to characterize nodular hydrates, a method is proposed for the preparation of sediment samples containing segregated hydrates masses, and a series of triaxial compression tests are carried out on the samples containing spherical hydrates with two kinds of particle sizes at a certain volume fraction. The paper presents triaxial stress–strain curves for the samples containing spherical hydrates. A model for predicting elastic modulus is established. The results present two distinct stages in the triaxial compression tests of silty clay sediments containing spherical hydrates; they also show that the elastic moduli predicted by the model are in good agreement with the experimental results when the model parameters are set at α = 0.5 and β = −0.21. These results provide fundamental mechanical parameters for the safety evaluation of strata containing segregated gas hydrates.

Nitrogen input enhances microbial carbon use efficiency by altering plant–microbe–mineral interactions - Xuehui Feng; Shuqi Qin; Dianye Zhang; Pengdong Chen; Jie Hu; Guanqin Wang; Yang Liu; Bin Wei; Qinlu Li; Yuanhe Yang; Leiyi Chen (Global Change Biology, 2022)
Microbial growth and respiration are at the core of the soil carbon (C) cycle, as these microbial physiological performances ultimately determine the fate of soil C. Microbial C use efficiency (CUE), a critical metric to characterize the partitioning of C between microbial growth and respiration, thus controls the sign and magnitude of soil C‐climate feedback. Despite its importance, the response of CUE to nitrogen (N) input and the relevant regulatory mechanisms remain poorly understood, leading to large uncertainties in predicting soil C dynamics under continuous N input. By combining a multi‐level field N addition experiment with a substrate‐independent 18 O‐H 2 O labelling approach as well as high‐throughput sequencing and mineral analysis, here we elucidated how N‐induced changes in plant–microbial–mineral interactions drove the responses of microbial CUE to N input. We found that microbial CUE increased significantly as a consequence of enhanced microbial growth after 6‐year N addition. In contrast to the prevailing view, the elevated microbial growth and CUE were not mainly driven by the reduced stoichiometric imbalance, but strongly associated with the increased soil C accessibility from weakened mineral protection. Such attenuated organo–mineral association was further linked to the N‐induced changes in the plant community and the increased oxalic acid in the soil. These findings provide empirical evidence for the tight linkage between mineral‐associated C dynamics and microbial physiology, highlighting the need to disentangle the complex plant–microbe–mineral interactions to improve soil C prediction under anthropogenic N input.

The fate of flavonoids after oral administration: a comprehensive overview of its bioavailability - Abid Naeem; Yang Ming; Hu Pengyi; Kang Yong Jie; Liu Yali; Zhang Haiyan; Xiao Shuai; Li Wenjing; Wu Ling; Zhang Ming Xia; Liu Shan Shan; Zheng Qin (Critical Reviews in Food Science and Nutrition, 2022)

Electrospun nanofibers food packaging: trends and applications in food systems - Dur E. Sameen; Saeed Ahmed; Rui Lu; Rui Li; Jianwu Dai; Wen Qin; Qing Zhang; Suqing Li; Yaowen Liu (Critical Reviews in Food Science and Nutrition, 2022)

Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum - Li Cheng; Xi Zheng; Qin Li; Meng-Sha Wei; Chun-Mei Chen; Hu-Cheng Zhu; Chang-Li Zeng; Xin-Cai Hao; Yong-Hui Zhang (Natural Product Research, 2022)

Intensified rainfall in the wet season alters the microbial contribution to soil carbon storage - Jinge Zhou; Jingfan Zhang; Hans Lambers; Jingtao Wu; Guoming Qin; Yingwen Li; Yongxing Li; Zhian Li; Jun Wang; Faming Wang (Plant and Soil, 2022)

Total, bioavailable and free 25-hydroxyvitamin D are associated with the prognosis of patients with non-small cell lung cancer - Si-Min Peng; Na Yu; Jun Che; Jia-Ying Xu; Guo-Chong Chen; Da-Peng Li; Yu-Song Zhang; Li-Qiang Qin (Cancer Causes & Control, 2022)

Secretory phospholipase A2 group XIIBs play potential roles in intestine antibacterial responses in seahorse - Wanghong Xiao; Geng Qin; Yanhong Zhang; Bo Zhang; Tao Li; Zelin Chen; Qiang Lin (Journal of Fish Diseases, 2022)

Basin‐scale approach needed for Yangtze River fisheries restoration - Binsong Jin; Kirk O. Winemiller; Wenwei Ren; Dave Tickner; Xiaohua Wei; Li Guo; Qin Li; Hui Zhang; Paulo Santos Pompeu; Marc Goichot; Sikai Wang; Ruichang Shen; et al. (Fish and Fisheries, 2022)
The Yangtze River contains the highest fish diversity and most important inland fishery resources in China, but its biota and ecosystem services face an uncertain future. The river and its basin have undergone vast changes from centuries of human impacts, and fish stocks are in a particularly dire situation. A complete 10‐year moratorium on commercial fishing within the entire Yangtze River was implemented starting in January 2021. By itself, the ban on fishing will unlikely guarantee full recovery. We conclude that multiple human impacts to the basin and its fish stocks require multidisciplinary strategies implemented at the whole basin scale for effective conservation.

Treatment of Wastewater-CPL by Biochar-Based Fenton-Like Catalyst in the Presence of Micro-nano Bubbles - Ruiling Zhang; Jiajun Wang; Jianyu Yang; Songyan Qin; Feiyue Li; Lixin Zhao; Zhe Zhu (Water, Air, & Soil Pollution, 2022)

De Novo SMARCC2 Variant in a Chinese Woman with Coffin-Siris Syndrome 8: a Case Report with Mild Intellectual Disability and Endocrinopathy - Sheng Yi; Mengting Li; Qi Yang; Zailong Qin; Shang Yi; Juanjuan Xu; Junjie Chen; Hao Wei; Yaoyao Jiang; Rongmin Wei; Qinle Zhang; Chengyun Yang; et al. (Journal of Molecular Neuroscience, 2022)

Whole-Transcriptome Analysis of Serum L1CAM-Captured Extracellular Vesicles Reveals Neural and Glycosylation Changes in Autism Spectrum Disorder - Yannan Qin; Li Cao; Jinyuan Zhang; Haiqing Zhang; Shuang Cai; Bo Guo; Fei Wu; Lingyu Zhao; Wen Li; Lei Ni; Liying Liu; Xiaofei Wang; et al. (Journal of Molecular Neuroscience, 2022)

Identification and feeding characteristics of the mixotrophic flagellate Poterioochromonas malhamensis, a microalgal predator isolated from planting water of Pontederia cordata - Hao Yan; Qin Li; Bo Chen; Mei Shi; Tingting Zhang (Environmental Science and Pollution Research, 2022)

Environmental risks and the potential benefits of nanopesticides: a review - Zhenlan Xu; Tao Tang; Qin Lin; Jianzhong Yu; Changpeng Zhang; Xueping Zhao; Melanie Kah; Lingxiangyu Li (Environmental Chemistry Letters, 2022)

Galanin enhanced insulin-mediated intracellular signaling by regulating the stability of membrane-localized insulin/IR - GuangZhi Li; Yongting Qin; Shizhen Wang; Jie Ni; Dongmei Zhang (Cell Biochemistry and Biophysics, 2022)

Effects of dietary protein concentration on growth and anti-oxidant capacity of coho salmon Oncorhynchus kisutch (Walbaum, 1792) alevins - Cong-mei Xu; Hai-rui Yu; Qin Zhang; Ling-yao Li; Jing-jing Fan; Meng-jie Guo; Fang-hui Li; Xiang-yi Qiu; Ling-ling Shan (Aquaculture International, 2022)

In vitro Scolicidal Efficacy of 5-Fluorouracil and Radiation Against Protoscoleces of Echinococcus granulosus Sensu Lato - Pengfei Lu; Jun Li; Rui Mao; Hongzhi Qi; Liping Yang; Qin Zhou; Mengxiao Tian; Wenbao Zhang; Yongxing Bao (Acta Parasitologica, 2022)

Quinoline, with the active site of 8‐hydroxyl, efficiently inhibits Micropterus salmoides rhabdovirus (MSRV) infection in vitro and in vivo - Bo‐Yang Li; Fei Yang; Zhong‐Yu Zhang; Yu‐Feng Shen; Tao Wang; Liang Zhao; Jia‐Cheng Qin; Fei Ling; Gao‐Xue Wang (Journal of Fish Diseases, 2022)
Micropterus salmoides rhabdovirus (MSRV) is an significant pathogen that causes high mortality and related economic losses in bass aquaculture. There is no effective or approved therapy to date. In this study, we evaluated the anti‐MSRV effects of 22 quinoline derivatives in grass carp ovary (GCO) cells. Among these compounds, 8‐hydroxyquinoline exhibited valid inhibition in decreasing MSRV nucleoprotein gene expression levels of 99.3% with a half‐maximal inhibitory concentrations (IC 50 ) value of 4.66 μM at 48 h. Moreover, 8‐hydroxyquinoline significantly enhanced a protective effect in GCO cells by reducing the cytopathic effect (CPE). By comparing the anti‐MSRV activity of 22 quinoline derivatives, we found that 8‐hydroxyquinoline possessed the efficient active site of 8‐hydroxyl and inhibited MSRV infection in vitro. For in vivo studies, 8‐hydroxyquinoline via intraperitoneal injection exhibited an antiviral effect in MSRV‐infected largemouth bass by substantially enhancing the survival rate by 15.0%. Importantly, the viral loads in the infected largemouth bass notably reduced in the spleen on the third days post‐infection. Overall, 8‐hydroxyquinoline was considered to be an efficient agent against MSRV in aquaculture.

Comparative Transcriptomics of Gonads Reveals the Molecular Mechanisms Underlying Gonadal Development in Giant Freshwater Prawns (Macrobrachium rosenbergii) - Guang Yang; Zhendong Qin; Zhijie Lu; Rishen Liang; Lijuan Zhao; Gan Pan; Li Lin; Kai Zhang (Journal of Marine Science and Engineering, 2022)
The giant freshwater prawn, Macrobrachium rosenbergii, is a prawn that has economic significance throughout the world. It exhibits sex-related growth dimorphism, whereby the males grow significantly more rapidly than the females. Therefore, a study on the molecular regulatory mechanism, which underlies the sexual differentiation of M. rosenbergii, is of both scientific and commercial importance. However, a scarcity of genomic and transcriptomic resources severely limits our knowledge of the sexual differentiation mechanisms in M. rosenbergii. Here, transcriptome sequencing of several gonadic samples of males and females in M. rosenbergii was performed to investigate the molecular basis underlying gonadal development. Our results showed that 2149 unigenes presented as differentially expressed genes (DEGs) in the ovaries of females compared to the testes of males, which contained 484 down-regulated and 1665 up-regulated genes. Enrichment analysis of DEGs revealed many of these genes to be related to sexual differentiation and gonadal development. From our transcriptome analyses, and as confirmed by quantitative real-time PCR, male-related genes (Mrr, MRPINK, IR, IAGBP, TESK1, and dsx) in the testes were significantly up-regulated, and female-related genes (ERR, Sxl3, cyclinB, Dmrt99B, PPP2A, and ADCY9) in the ovaries were also significantly up-regulated. This indicates the potential role these genes play in the gonadal development of M. rosenbergii. Furthermore, multiple signal transduction pathways relating to gonadal maturation and spermatogenesis, including MAPK, were identified herein. Our data also supports previous ideas that IAG and IAGBP-IR signaling schemes could help in the regulation of testis’ development in M. rosenbergii and the ERR gene could regulate ovarian development by affecting the expression of cyclinB, PPP2A, and ADCY9. The data from this study provides incredibly usefully genomic resources for future research on the sexual differentiation and practical aquaculture of M. rosenbergii.

Developmental Expression Pattern of the Piwi1 Gene, Timing of Sex Differentiation and Maturation in Artificially Produced Juvenile Boring Giant Clam, Tridacna crocea - Yinyin Zhou; Yunqing Li; Qingliang Liao; Gongpengyang Shi; Yanpin Qin; Yuehuan Zhang; Haitao Ma; Jun Li; Ziniu Yu (Frontiers in Marine Science, 2022)
P-element-induced wimpy testis ( Piwi ) is a key gene involved in germ cell development in a diverse range of organisms. However, in giant clams, the function of Piwi remains unclear. In the present study, we isolated the full-length cDNA of Piwi ortholog ( Tc-Piwi1 ) and analyzed its expression patterns in the gonads of adult and juvenile Tridacna crocea . The results of qPCR showed that the transcript of Tc-Piwi1 was mainly expressed in gonad tissue. In addition, the relative expression level of Tc-Piwi1 increased with the proliferation of male and female germ cells during the adult gonad development stage, suggesting that Tc-Piwi1 might be involved in gametogenesis. In situ hybridization revealed that Tc-Piwi1 RNA was located in female and male germ cells and strongly expressed in male germ cells in the early stage. Furthermore, immunohistochemical experiments further confirmed that Tc-Piwi1 was mainly located in primordial germ cells (PGCs), germ stem cells (GSCs), and female and male germ cells of early development, so it could be used as a marker gene of T. crocea germ cells. Whole-mount in situ hybridization suggested that Tc-Piwi1 was of maternal origin and located in two clusters of cells in the trochophore-larvae stage, implying that these cells might be putative PGCs during the embryo development. Finally, Tc-Piwi1 was used as a molecular marker to elucidate the gonadal formation, sex differentiation, and gonadal maturation process of juvenile T. crocea for the first time in the Tridacna family. Collectively, all these results revealed that Tc-Piwi1 was involved in germline formation and sex differentiation in T. crocea .

Improved Process Management of Glacial Lake Outburst Flood Hazards by Integrating Modular Monitoring, Assessment, and Simulation - Xiang Wang; Guo Chen; Xiaoai Dai; Jingjing Zhao; Xian Liu; Yu Gao; Junmin Zhang; Yongjun Chen; Xiaozhen Li; Wenyi Qin; Peng Wang (Water Resources Management, 2022)

Understanding the impacts induced by cut-off thresholds and likelihood measures on confidence interval when applying GLUE approach - Zhenya Li; Tao Yang; Na Zhang; Yandong Zhang; Jiahu Wang; Chong-Yu Xu; Pengfei Shi; Youwei Qin (Stochastic Environmental Research and Risk Assessment, 2022)

Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction - Qin Zhong; Zongren Li; Wenjun Wang; Lei Zhang; Kunlun He (Science China Life Sciences, 2022)

The Effects of Ground and Treadmill Running on Energy Metabolism and Muscle Contractile Properties: A Randomized Cross-Over Study - Yuan Zhou; Jian-gang Chen; Xiao-long Li; Xin-liang Pan; Yi-zheng Zhou; Zheng-ao Li; Zhi-cheng Liang; Jia-min Long; Ming-ze Qin; Jing Zhang; Bing Shi; Bing-jun Wan; et al. (Journal of Science in Sport and Exercise, 2022)
Purpose This study aimed to compare the effects of ground and treadmill running on energy metabolism and muscle contractile properties, providing a basis for the general public to choose running venues. Methods Ten male college students (age, 20.10 ± 1.53 years; height, 176.20 ± 5.49 cm; weight, 72.14 ± 8.25 kg; body fat percent, 12.41% ± 4.65%) were recruited in this study. Energy expenditure (EE) was measured using the accelerometer (GT9X) combined with specific estimation equations. Average heart rate (HR) was measured using a heart rate band (Polar). Muscle contractile properties were assessed by measuring muscle displacement (Dm) and contraction velocity (Vc) using tensiomyography (TMG-S1). Blood glucose (Glu) and lactate (Lac) were measured by portable devices (eB-G and Lactate Scout). The running speed was 9 km/h and the duration was 25 min. Two-way ANOVA (protocol × time) was used to analyze the effect of running protocols on energy metabolism and muscle contractile properties. Results EE of treadmill running was significantly higher than EE of ground running (protocol main effect, P < 0.001), and HR of treadmill running was significantly higher than that of ground running in the first testing time (protocol simple effect, P = 0.026; protocol × time interaction P = 0.043). The decrease in Dm of the rectus femoris after treadmill running was significantly higher than that of ground running (protocol main effect, P = 0.009). The interaction of different running protocols and testing times on Lac was significant ( P = 0.025), but all results of the simple effects analysis were not statistically significant ( P > 0.05). Conclusion Our study found a difference in energy expenditure between treadmill and ground running at 9 km/h with duration of 25 min. In addition, treadmills are more likely to cause a decrease in muscle displacement distance of the rectus femoris measured after exercise than ground running. Future studies are needed to further investigate whether the differences are induced by internal metabolism or the environmental conditions of running.

Evaluating crop coefficient and associated processes in a drip irrigation with different color of biodegradable film mulching - Ning Chen; Xianyue Li; Haibin Shi; Qi Hu; Yuehong Zhang; Qin’ge Dong; Guoshuai Wang (Irrigation Science, 2022)

Protective Effect of Selenium-Enriched Green Tea on Carbon Tetrachloride-Induced Liver Fibrosis - Lin Zhang; Jia-Ying Xu; Yanyan Wei; Shi-Lin Gao; Lin Wang; Jia-Yang Zheng; Minghua Gu; Li-Qiang Qin (Biological Trace Element Research, 2022)

Alpine vegetation responses to snow phenology in the Chinese Tianshan mountainous region - Bo Zhang; Xue-mei Li; Chao Li; Christine Nyiransengiyumva; Qi-yong Qin (Journal of Mountain Science, 2022)

Application of pretensioned grouting support in repairing surrounding rock damaged by dynamic load - Zhongcheng Qin; Yongle Liu; Jinxiao Liu; Bin Cao; Feng Zhang; Wenxin Li (Arabian Journal of Geosciences, 2022)

Study on the Individual Coloring Mechanism of Iridescent Cells in the Mantle of the Boring Giant Clam, Tridacna crocea - Yunqing Li; Yinyin Zhou; Jinkuan Wei; Gongpengyang Shi; Qingliang Liao; Shuming Guo; Zihua Zhou; Jun Li; Yanping Qin; Haitao Ma; Ziniu Yu; Yuehuan Zhang (Frontiers in Marine Science, 2022)
Giant clams are marine bivalves that inhabit Indo-Pacific coral reefs. The boring giant clam, Tridacna crocea , exhibits bright and conspicuous mantle coloration based on the specialized cells (iridocytes) that generate structural colors. In order to illustrate the coloring mechanism of individual iridocytes, the reflection spectra curve of iridocytes was obtained by a micro-hyperspectral imager. TEM images were obtained to show the inner nanostructures of iridocytes. FDTD simulation was conducted to analyze the relationship between the color of iridocytes and the unique lamellar structure. We found that the laminae in the regular arrangement within cells govern the coloration of individual iridocytes. With the gradual increase of lamellar thickness and spacing, the color of the structure varies from bright violet to orange-red, forming a full visible spectrum. This study provides a new understanding of the various colors produced by individual iridocytes.

Hanseniaspora pseudoguilliermondii Improves the Flavor of Tilapia Fish Protein Hydrolysates - Shiguo Liu; Qiao Zhang; Qin Xiang; Lirui Duan; Zhisheng Pei; Yongcheng Li (Journal of Aquatic Food Product Technology, 2022)

A new sesquiterpene from mangrove endophytic fungus Aspergillus sp. GXNU-MA1 - Dexiong Zhou; Wenxiu Zhang; Lili Hao; Xiaoya Qin; Ruiyun Yang; Jun Li; Xishan Huang (Natural Product Research, 2022)

A new depsidone derivative from mangrove endophytic fungus Aspergillus sp. GXNU-A9 - Lili Hao; Dexiong Zhou; Xiaoya Qin; Wenxiu Zhang; Ruiyun Yang; Jun Li; Xishan Huang (Natural Product Research, 2022)

QTL identification, fine mapping, and marker development for breeding peanut (Arachis hypogaea L.) resistant to bacterial wilt - Feiyan Qi; Ziqi Sun; Hua Liu; Zheng Zheng; Li Qin; Lei Shi; Qingzheng Chen; Haidong Liu; Xiufang Lin; Lijuan Miao; Mengdi Tian; Xiao Wang; et al. (Theoretical and Applied Genetics, 2022)
Key message A major QTL, qBWA12 , was fine mapped to a 216.68 kb physical region, and A12.4097252 was identified as a useful KASP marker for breeding peanut varieties resistant to bacterial wilt. Abstract Bacterial wilt, caused by Ralstonia solanacearum , is a major disease detrimental to peanut production in China. Breeding disease-resistant peanut varieties is the most economical and effective way to prevent the disease and yield loss. Fine mapping the QTLs for bacterial wilt resistance is critical for the marker-assisted breeding of disease-resistant varieties. A recombinant inbred population comprising 521 lines was used to construct a high-density genetic linkage map and to identify QTLs for bacterial wilt resistance following restriction-site-associated DNA sequencing. The genetic map, which included 5120 SNP markers, covered a length of 3179 cM with an average marker distance of 0.6 cM. Four QTLs for bacterial wilt resistance were mapped on four chromosomes. One major QTL, qBWA12 , with LOD score of 32.8–66.0 and PVE of 31.2–44.8%, was stably detected in all four development stages investigated over the 3 trial years. Additionally, qBWA12 spanned a 2.7 cM region, corresponding to approximately 0.4 Mb and was fine mapped to a 216.7 kb region by applying KASP markers that were polymorphic between the two parents based on whole-genome resequencing data. In a large collection of breeding and germplasm lines, it was proved that KASP marker A12.4097252 can be applied for the marker-assisted breeding to develop peanut varieties resistant to bacterial wilt. Of the 19 candidate genes in the region covered by qBWA12 , nine NBS-LRR genes should be further investigated regarding their potential contribution to the resistance of peanut against bacterial wilt.

Reconstruction of alpine snowfall in southern Kazakhstan based on oxygen isotopes in tree rings - Li Qin; Kainar Bolatov; Huaming Shang; Shulong Yu; Xiaohua Gou; Maisupova Bagila; Aigerim Bolatova; Utebekova Ainur; Ruibo Zhang (Theoretical and Applied Climatology, 2022)

An imputed whole-genome sequence-based GWAS approach pinpoints causal mutations for complex traits in a specific swine population - Guorong Yan; Xianxian Liu; Shijun Xiao; Wenshui Xin; Wenwu Xu; Yiping Li; Tao Huang; Jiangtao Qin; Lei Xie; Junwu Ma; Zhiyan Zhang; Lusheng Huang (Science China Life Sciences, 2022)

Synthesis and fungicidal activity of methyl (E)-1-(2-((E)-2-methoxy-1-(methoxyimino)-2-oxoethyl)benzyl)-2-(1-arylidene)hydrazine-1-carboxylates †‡ - Xuelian Liu; Changqing Jia; Fahong Yin; Li Zhang; Shijie Du; Jia-Qi Li; Yumei Xiao; Zhaohai Qin (Molecular Diversity, 2022)

LncRNA OGFRP1 promotes cell proliferation and suppresses cell radiosensitivity in gastric cancer by targeting the miR-149-5p/MAP3K3 axis - Huihao Qin; Xing Li; Wei Zhang; Zhiqiang Ding (Journal of Molecular Histology, 2022)

The Predominance of Nongrowing Season Emissions to the Annual Methane Budget of a Semiarid Alpine Meadow on the Northeastern Qinghai-Tibetan Plateau - Hongqin Li; Jingbin Zhu; Fawei Zhang; Gang Qin; Yongsheng Yang; Yikang Li; Junbang Wang; Guangmin Cao; Yingnian Li; Huakun Zhou; Mingyuan Du (Ecosystems, 2022)

Distribution patterns of SOC/TN content and their relationship with topography, vegetation and climatic factors in China’s north-south transitional zone - Junhua Zhang; Lianqi Zhu; Guodong Li; Fang Zhao; Jingting Qin (Journal of Geographical Sciences, 2022)

A reconstruction of June–July temperature since AD 1383 for Western Sichuan Plateau, China using tree‐ring width - Yu Zhang; Jinjian Li; Shu Wang; Xuemei Shao; Ningsheng Qin; Wenling An (International Journal of Climatology, 2022)
Global warming has a significant impact on the ecosystem of the high‐altitude areas of the Tibetan Plateau, such as land degradation and the rapid retreat of glaciers. It is important to understand the effects of global warming occurring over hundreds or thousands of years. However, the long‐term reconstruction of temperature is still lacking for the region of Western Sichuan Plateau (WSP). In this study, we reconstructed summer (June–July) temperatures back to 1383 for the WSP region based on a significant positive correlation between the standard chronology and summer temperature. The reconstruction passed statistical tests and explained 55.4% of the climatic variance in the period for which data are available (1962–2005). There have been five periods with warm summers and five with cold summers during the past 623 years. Warm periods occurred in 1383–1445, 1525–1590, 1700–1724, 1825–1870, and 1930–1960, while relatively cold periods occurred in 1446–1524, 1591–1675, 1725–1824, 1900–1929, and 1961–1990. A comparison with observed data and regional temperature reconstruction series shows that the reconstruction has a high degree of consistency and is indicative and reliability. The spatial correlation was analysed with Climatic Research Unit gridded data to detect the spatial representativeness of the reconstruction, confirming that the reconstruction has a strong regional temperature signal for the WSP. Furthermore, ensemble empirical mode decomposition indicates quasi‐oscillations of 2.8–3.3, 6.4–8.3, 11.1–14.2, 25–38.4, 89, and 138 years in the reconstructed temperature time series during the past 623 years. El Niño Southern Oscillation cycles, solar activity, and Atlantic multi‐decadal oscillation may be the primary forcing factors. Meanwhile, the coordinated action of temperature‐induced drought stress with a late growing season related to delayed snowmelt can potentially be attributed to the divergence problem (observed around 2005).

Inhibition of red chlorophyll catabolite reductase improved chlorophyll and carotenoid synthesis in tobacco - Chen Dong; Mei Zhang; Fang Wei; Yushuang Guo; Lili Qin; Pan Wei; Yubo Wang; Lifeng Jin; Weina Song; Tao Sun; Feng Li; Ran Wang (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

The phycocyanin-chlorophyll-protein complexes isolated from Chroomonas placoidea - Min Chen; Qin Li; Yuxuan Wang; Jing Wang; Kun Zhang (Journal of Oceanology and Limnology, 2022)

Establishment of Galectin-3 Time-resolved Fluoroimmunoassay and its Application in Idiopathic Membranous Nephropathy - Xiaomei Yu; Lingli Chen; Bo Lin; Li Zhang; Xue Yang; Xiaobin Liu; Pengguo Xia; Yueming Liu; Shaoxiong Zheng; Xiumei Zhou; Yigang Wang; Yuan Qin; et al. (Journal of Fluorescence, 2022)

QTL mapping integrated with BSA-Seq analysis identifies a novel gene conferring resistance to brown planthopper from common wild rice (Oryza rufipogon Griff.) - Xuan Wang; Yue Han; Yue-xiong Zhang; Biao Deng; Bi-qiu Wu; Xin-ying Guo; Yu-fen Qin; Yao-yu Fang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Euphytica, 2022)

Characterization and genomic analysis of a Demerecviridae phage SP76 with lytic multiple-serotypes of Salmonella - Hui Wang; Yun Shen; Pei LI; Yuyi Xiao; Yanxiu Li; Xiapei Hu; Zhuohao Wang; Zile Cheng; Zitong Wang; Qingxin Liu; Si Qin; Xiang Huo; et al. (Archives of Microbiology, 2022)

Cancer metabolism and tumor microenvironment: fostering each other? - Yiyuan Yuan; Huimin Li; Wang Pu; Leilei Chen; Dong Guo; Hongfei Jiang; Bo He; Siyuan Qin; Kui Wang; Na Li; Jingwei Feng; Jing Wen; et al. (Science China Life Sciences, 2022)

Risk assessment of coal and gas outburst in driving face based on finite interval cloud model - Guorui Zhang; Enyuan Wang; Zhonghui Li; Ben Qin (Natural Hazards, 2022)

Effect of pre-oxidation process on V2O5/AC catalyst for the selective catalytic reduction of NOx with NH3 - Jiahua Xie; Mengyu Li; Zihua Wu; Yiqing Zeng; Shule Zhang; Jing Liu; Qin Zhong (Environmental Science and Pollution Research, 2022)

A survey of brain network analysis by electroencephalographic signals - Cuihua Luo; Fali Li; Peiyang Li; Chanlin Yi; Chunbo Li; Qin Tao; Xiabing Zhang; Yajing Si; Dezhong Yao; Gang Yin; Pengyun Song; Huazhang Wang; et al. (Cognitive Neurodynamics, 2022)

East Asian summer monsoon changes in subtropical China since late Pleistocene: Evidence from the Ailuropoda-Stegodon fauna - Zhi-wen Li; Li Sun; Bao-sheng Li; Feng-nian Wang; Ding-ding Du; You-gui Song; Hui-Juan Zhang; Liu-qin Chen; Dan Xu (Journal of Mountain Science, 2022)

Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function - Huijie Zhang; Jiawei Qin; Xinqiang Lan; Weirong Zeng; Jing Zhou; Tian-E Huang; Wan-Li Xiao; Qi-Quan Wang; Sujiao Sun; Weiting Su; Wenhui Nie; Shan Yang; et al. (Biogerontology, 2022)

Advenella mandrilli sp. nov., a bacterium isolated from the faeces of Mandrillus sphinx - Qiong Wang; Xiu-Lin Han; Zhi-Qin Fang; Chen-Lu Zhang; Chun Li; Tao Lu (Antonie van Leeuwenhoek, 2022)

PrupeFUL4 regulates ripening and softening of peach fruits through ethylene biosynthesis - Shaoyu Zhang; Xianju Wang; Ze Xu; Pei Shi; Meijiao Gu; Tongyang Kang; Qin Li; Dong Zhang; Caiping Zhao (Acta Physiologiae Plantarum, 2022)

Cu/Zn Superoxide Dismutase and Catalase of Yangtze Sturgeon, Acipenser dabryanus: Molecular Cloning, Tissue Distribution and Response to Fasting and Refeeding - Qingchao Shi; Xiaoqin Xiong; Zhengyong Wen; Chuanjie Qin; Rui Li; Zhiyong Zhang; Quan Gong; Xiaoyun Wu (Fishes, 2022)
Superoxide dismutase and catalase are two major antioxidant enzymes in the fish antioxidant defense system, which can remove excess reactive oxygen species and protect fish from stress-induced oxidative damage. The present study aimed to clone the sequences of Yangtze sturgeon, Acipenser dabryanus, Cu/Zn superoxide dismutase (AdCu/Zn-SOD) and catalase (AdCAT), and to explore changes of gene expression in the liver and intestine during fasting and refeeding. A total of 120 fish were exposed to four fasting and refeeding protocols (fasting for 0, 3, 7, or 14 d and then refeeding for 14 d). The coding sequences of AdCu/Zn-SOD and AdCAT encoded 155 and 526 amino acid proteins, respectively, both of which were expressed mainly in the liver. During fasting, when compared to the control group, liver AdCu/Zn-SOD expression was significantly higher in the 3- and 14-d groups, whereas its intestinal expression increased significantly only in the 7-d group. Liver AdCAT expression increased significantly in the 3-, 7-, and 14-d groups. During refeeding, liver AdCu/Zn-SOD expression increased significantly in the 3-, 7-, and 14-d groups compared with those in the control group. Similarly, intestinal AdCu/Zn-SOD expression increased significantly in the 3- and 7-d groups. Moreover, intestinal AdCAT expression was significantly higher in the 3-d group than in the control group, but decreased significantly in the 14-d group. Our findings indicated that AdCu/Zn-SOD and AdCAT play important roles in protecting fish against starvation-induced oxidative stress. Yangtze sturgeon exhibited the potential to adapt to a starvation and refeeding regime.

Modelling deep convective activity using lightning clusters and machine learning - Manxing Shi; Wei Zhang; Peng Fan; Qihao Chen; Zhipeng Liu; Qin Li; Xiuguo Liu (International Journal of Climatology, 2022)
Retrieving thunderstorm activity through specific thermodynamic and kinematic parameters is paramount for predicting deep convective weather and investigating long‐term climatology of storm. However, the reliability of the relationship between parameters and convective events is restricted by the modelling methods and sampling of thunderstorm activity. There is no objective definition of a thunderstorm, so the clustering method is applied to the cloud‐to‐ground (CG) lightning stroke data in Central China to identify lightning clusters. These clusters are then gridded and associated with environmental variables derived from ERA5 reanalysis. Finally, machine learning (ML) technologies are applied to model the occurrence of thunderstorms. In addition, ERA5 is also evaluated. The parameters related to moisture and lapse rate calculated by ERA5 are close to sounding measurements, such as Td850, PW, LR700_400 and KI, whose correlation coefficients exceed 0.90. ERA5 has a good estimation of some parameters that are susceptible to the influence of the boundary layer. Compared with the lightning strike‐based scheme, our scheme obtains the best performance index values. An agreement between observations and predictions based on lightning clusters is also evident from the diurnal cycle of thunderstorm probabilities. Although thunderstorm activity on complex terrain is underestimated, the created ML model can explain 61.4% of the variance in the observed frequency. The results of the significance test reveal that there are statistically significant differences between the soundings corresponding to some isolated CG strikes and the thunderstorm class, but the distribution is the same as that of the non‐thunderstorm class. Solar radiation, topographic features and lake distribution play a major role in promoting the occurrence and development of thunderstorms.

New Insight Into the Mechanism of Ecological Effects of Artificial Habitats: Elucidating the Relationship Between Protists Associated With Artificial Reefs and Adjacent Seawater - Ruolin Li; Yu Guo; Chuanxin Qin; Shuo Zhang; Dongping Ji; Hui Zhang; Jing Wang; Naiqian Zhao (Frontiers in Marine Science, 2022)
Artificial habitat deployment can restore natural habitats or supplement existing natural habitats. The effect of resource proliferation and protection is obvious. However, few reports have addressed the biological community association between artificial habitats and adjacent environments. Here, Illumina sequencing of 18S rDNA was performed, and the diversity, community structure, and co-occurrence networks of protists in different layers of artificial reefs (ARs) and adjacent seawater (WAR) were described to verify that constructing ARs in Bailong Pearl Bay improves local spatial heterogeneity and functional diversity. In terms of the degree of species interaction, the protist communities were ranked as follows: surface and bottom of WAR > ARs and WAR > different layers of ARs. The α-diversity of protists associated with ARs and WAR decreased with an increase in depth. Protist diversity was greater in WAR than in ARs. β-Diversity analysis revealed significant differences in protist community structure between WAR and ARs ( P < 0.05), and the upper layers of ARs and the middle or bottom layers of ARs differed. The key topological features of protist networks showed more positive interspecific interactions in the AR-associated protist community, a higher degree of niche differentiation, and higher complexity and stability. The keystone protists in the bottom seawater layer displayed community functions that were biased toward initial fixation in the ocean carbon cycle. The AR-associated protist community tended to participate in carbon transfer in the food chain and decomposition and utilization of dissolved organic matter (DOM). This study revealed significant differences in protist community structure between ARs and the adjacent environment, and the ecological functions of the key phyla were found to be related. In conclusion, protist communities in WAR may provide food sources for AR-associated heterotrophic protists. A variety of key phyla associated with ARs have biological roles in the carbon pump via their ecological characteristics.

Influence of Functional Group Modification on the Toxicity of Nanoplastics - Haihong Zhang; Haodong Cheng; Yudi Wang; Zhenghua Duan; Wenjie Cui; Yansong Shi; Li Qin (Frontiers in Marine Science, 2022)
Nanoplastics (NPs) are ubiquitous in harvested organisms at various trophic levels, and more concerns on their diverse responses and wide species-dependent sensitivity are continuously increasing. However, systematic study on the toxic effects of NPs with different functional group modifications is still limited. In this review, we gathered and analyzed the toxic effects of NPs with different functional groups on microorganisms, plants, animals, and mammalian/human cells in vitro. The corresponding toxic mechanisms were also described. In general, most up-to-date relevant studies focus on amino (−NH 2 ) or carboxyl (−COOH)-modified polystyrene (PS) NPs, while research on other materials and functional groups is lacking. Positively charged PS-NH 2 NPs induced stronger toxicity than negatively charged PS-COOH. Plausible toxicity mechanisms mainly include membrane interaction and disruption, reactive oxygen species generation, and protein corona and eco-corona formations, and they were influenced by surface charges of NPs. The effects of NPs in the long-term exposure and in the real environment world also warrant further study.

Two new threonine-containing metabolites from fungus Curvularia inaequalis strain HS-FG-257 - Shao-Yong Zhang; Jian-Song Li; Hui Zhang; Huan Qi; Rui-Jun Wang; Chou-Fei Wu; Li-Qin Zhang; An-Liang Chen; Ji-Dong Wang; Zhi-Kui Hao (Natural Product Research, 2022)

Synthesis, characterization, and antioxidant activity of carboxymethyl chitosan derivatives containing sulfonium salt - Xueqi Sun; Jingjing Zhang; Yingqi Mi; Qin Miao; Wenqiang Tan; Qing Li; Zhanyong Guo (Journal of Oceanology and Limnology, 2022)

LncSNHG3 promotes hepatocellular carcinoma epithelial mesenchymal transition progression through the miR-152-3p/JAK1 pathway - Hong Li; Yu Wu; Runmei Wang; Junmei Guo; Qin Yu; Lihe Zhang; Haiping Zhao; Hao Yang (Genes & Genomics, 2022)

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

Angiogenic effects of low molecular weight organic acids present in fulvic acids of different sources - Zhi Wang; Huifen Zhang; Yi Qin; Weifeng Dai; Baocai Li; Mi Zhang (Natural Product Research, 2021)

Antioxidant, DNA damage protective, antibacterial activities and nitrite scavenging ability of essential oil of Amomum kravanh from China - Qin Li; Liang-Liang Zhang; Jian-Guo Xu (Natural Product Research, 2021)

Lathyrane diterpenoids from Jatropha podagrica and their antitumor activities in human osteosarcoma cells - Han-Tao Yuan; Qun-Feng Li; Tian Tian; Chun-Yan Zhang; Zou-Qin Huang; Chun-Xiang Fan; Ke Mei; Jie Zhou; Xiao-Xiang Zhai; Si-Bo Li; Jian-Yong Zhu (Natural Product Research, 2021)

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Correction to: Comparative Transcriptome Analysis of Hybrid Population Provides Insights Into Starch Content in Sweet Potato (Ipomoea batatas L.) Storage Root - Zhen Qin; Aixian Li; Shunxu Dong; Qingmei Wang; Fuyun Hou; Haiyan Zhang (Plant Molecular Biology Reporter, 2021)

Genome-Wide Identification and Expression Analysis of the Carotenoid Cleavage Oxygenase Gene Family in Five Rosaceae Species - Jianrong Zhao; Jiyu Li; Jun Zhang; Dan Chen; Huping Zhang; Chunyan Liu; Gaihua Qin (Plant Molecular Biology Reporter, 2021)

Comparative Transcriptome Analysis of Hybrid Population Provides Insights Into Starch Content in Sweet Potato (Ipomoea batatas L.) Storage Root - Zhen Qin; Aixian Li; Shunxu Dong; Qingmei Wang; Fuyun Hou; Haiyan Zhang (Plant Molecular Biology Reporter, 2021)

Contribution and Coupling Effect of Adsorption on Clay Minerals and Organic Matter in the Early Diagenetic Stage of Coal Measures - Geng Li; Yong Qin; Haipeng Yao; Xianqing Zhou; Xiaohu Xiao; Zhen Zhang (Natural Resources Research, 2021)

Hydrogen Sulfide Maintains Good Nutrition and Delays Postharvest Senescence in Postharvest Tomato Fruits by Regulating Antioxidative Metabolism - Ting-Ying Zhong; Gai-Fang Yao; Sha-Sha Wang; Ting-Ting Li; Ke-Ke Sun; Jun Tang; Zhong-Qin Huang; Feng Yang; Yan-Hong Li; Xiao-Yan Chen; Lan-Ying Hu; Hua Zhang; et al. (Journal of Plant Growth Regulation, 2021)

Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology - Yuhong Zhang; Xu Chen; Qiqi Wang; Congcong Du; Wenbin Lu; Hong Yuan; Zhenzhen Zhang; Danqing Li; Xing Ling; Xiang Ren; Yang Zhao; Qi Su; et al. (Journal of Molecular Medicine, 2021)

Characterization of the novel hybrid cultivar E25 of Saccharina japonica in the northern farming region of China - Li Su; Ti Feng Shan; Jing Li; Su Qin Gao; Shao Jun Pang; Xiao Fei Leng; Yan Zhang; Ming Fu Zhang; Hong Tao Gao (Journal of Applied Phycology, 2021)

Neural responses to rapidly selecting color names with different novelty - Hanqing Ma; Yunyi Zhang; Jingyi Zhang; Yong Liu; Zhiliang Long; Huangyanqiu Ran; Jingwen Li; Yingmei Qin; Jia Zhao (Cognitive Neurodynamics, 2021)

Establishment of an immortalized cell line derived from the pupal ovary of Mythimna separata (Lepidoptera: Noctuidae) and identification of the cell source - Yan Tong; Lu-Qiang Cheng; Xuan Li; Xu-Peng Yu; Rui-Hao Shu; Ji-Hong Zhang; Qian Meng; Qi-Lian Qin; Kai Tang; Jian-Xiang Xu; Huan Zhang (Cell and Tissue Research, 2021)

A novel polymycovirus with defective RNA isolated from the entomopathogenic fungus Beauveria bassiana Vuillemin - Qin Kang; Le Li; Jincang Li; Songbai Zhang; Jiatao Xie; Qiyun Li; Zhengkun Zhang (Archives of Virology, 2021)

The complete genome sequence of a novel chrysovirus from the entomopathogenic fungus Beauveria bassiana Vuillemin - Le Li; Qin Kang; Songbai Zhang; Du Hai; Yang Lu; Li Sui; Zhengkun Zhang; Qiyun Li (Archives of Virology, 2021)

Tetraploid induction of Crassostrea hongkongensis and C. sikamea by inhibiting the polar body 1 release in diploid fertilized eggs - Yanping Qin; Zohaib Noor; Xingyou Li; Haitao Ma; Jun Li; Yinyin Zhou; Riguan Mo; Yuehuan Zhang; Ziniu Yu (Marine Life Science & Technology, 2021)

Wnt8a is one of the candidate genes that play essential roles in the elongation of the seahorse prehensile tail - Bo Zhang; Geng Qin; Lili Qu; Yanhong Zhang; Chunyan Li; Chunlei Cang; Qiang Lin (Marine Life Science & Technology, 2021)

The effect and prediction of diurnal temperature range in high altitude area on outpatient and emergency room admissions for cardiovascular diseases - Wenzhi Zhu; Xingfu Wei; Li Zhang; Qin Shi; Guoxiu Shi; Xiaofei Zhang; Minzhen Wang; Chun Yin; Feng Kang; Yana Bai; Yonghong Nie; Shan Zheng (International Archives of Occupational and Environmental Health, 2021)

Effects of organic acids on the chemotaxis profiles and biocontrol traits of antagonistic bacterial endophytes against root-rot disease in Panax notoginseng - Li Ma; Wu-Qin Wang; Rui Shi; Xue-Mei Zhang; Xin Li; Yu-Sen Yang; Ming He Mo (Antonie van Leeuwenhoek, 2021)

Two new isoquinoline alkaloids from the seeds of Nandina domestica - Juan Qin; Sheng-Yuan Zhang; Yu-Bo Zhang; Li-Feng Chen; Neng-Hua Chen; Zhong-Nan Wu; Ding Luo; Guo-Cai Wang; Yao-Lan Li (Natural Product Research, 2021)

Master regulator NtrC controls the utilization of alternative nitrogen sources in Pseudomonas stutzeri A1501 - Zhimin Yang; Qin Li; Yongliang Yan; Xiubin Ke; Yueyue Han; Shaoyu Wu; Fanyang Lv; Yahui Shao; Shanshan Jiang; Min Lin; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2021)
Pseudomonas stutzeri A1501 is a model strain used to study associative nitrogen fixation, and it possesses the nitrogen regulatory NtrC protein in the core genome. Nitrogen sources represent one of the important factors affecting the efficiency of biological nitrogen fixation in the natural environment. However, the regulation of NtrC during nitrogen metabolism in P. stutzeri A1501 has not been clarified. In this work, a phenotypic analysis of the ntrC mutant characterized the roles of NtrC in nitrogen metabolism and the oxidative stress response of P. stutzeri A1501. To systematically identify NtrC-controlled gene expression, RNA-seq was performed to further analyse the gene expression differences between the wild-type strain and the ∆ ntrC mutant under nitrogen fixation conditions. A total of 1431 genes were found to be significantly altered by ntrC deletion, among which 147 associative genes had NtrC-binding sites, and the pathways for nitrogen fixation regulation, nitrogenous compound acquisition and catabolism and nitrate assimilation were discussed. Furthermore, the oxidative stress-related gene ( katB ), which was upregulated by ntrC deletion, was suggested to be a potential target gene of NtrC, thus highlighting the importance of NtrC in nitrogenase protection against oxygen damage. Based on these findings, we propose that NtrC is a high-ranking element in the regulatory network of P. stutzeri A1501 that controls a variety of nitrogen metabolic and oxidative stress responsive traits required for adaptation to complex rhizosphere environments.

Whole-genome resequencing of 240 Gossypium barbadense accessions reveals genetic variation and genes associated with fiber strength and lint percentage - Jingwen Yu; Yixuan Hui; Jinhong Chen; Hurong Yu; Xinpeng Gao; Zhaohui Zhang; Qin Li; Shuijin Zhu; Tianlun Zhao (Theoretical and Applied Genetics, 2021)

Degradation of wetlands on the Qinghai-Tibetan Plateau causing a loss in soil organic carbon in 1966–2016 - Hailing Li; Tingting Li; Wenjuan Sun; Wen Zhang; Qing Zhang; Lijun Yu; Zhangcai Qin; Bin Guo; Jia Liu; Xingchu Zha (Plant and Soil, 2021)

Additive and Epistatic QTL on Cadmium (Cd) Tolerance Associated with Seed Germinating Ability in Rice - Changsheng Li; Peng Wang; Guangliang Wu; Yanning Wang; Qin Cheng; Yicong Cai; Dahu Zhou; Caijing Li; Xiangyu Zhang; Jingai Tan; Cuijuan Li; Haohua He; et al. (Journal of Plant Growth Regulation, 2021)

Sox2 controls asymmetric patterning of ameloblast lineage commitment by regulation of FGF signaling in the mouse incisor - Dan Li; Xiaofei Wang; Liping Yao; Huaixiang Jing; Tiantian Qin; Mingyue Li; Shuyu Zhang; Zhi Chen; Li Zhang (Journal of Molecular Histology, 2021)

Resistance to pokkah boeng disease in new and main sugarcane varieties cultivated in China - Hongli Shan; Xiaoyan Cang; Wei Qin; Wenfeng Li; Xiaoyan Wang; Rongyue Zhang; Yingkun Huang (Euphytica, 2021)

Nitrogen removal from ammonium- and sulfate-rich wastewater in an upflow anaerobic sludge bed reactor: performance and microbial community structure - Yongli Qin; Qiaoyan Wei; Yuanyuan Zhang; Haixiang Li; Yongrong Jiang; Junjian Zheng (Ecotoxicology, 2021)

High-K calc-alkaline to shoshonitic intrusions in SE Tibet: implications for metasomatized lithospheric mantle beneath an active continental margin - Ren-Zhi Zhu; Ewa Słaby; Shao-Cong Lai; Li-Hui Chen; Jiangfeng Qin; Chao Zhang; Shaowei Zhao; Fangyi Zhang; Wen-hang Liu; Mike Fowler (Contributions to Mineralogy and Petrology, 2021)

Historical and recent change in extreme climate over East Asia - Guoyu Ren; Johnny C. L. Chan; Hisayuki Kubota; Zhongshi Zhang; Jinbao Li; Yongxiang Zhang; Yingxian Zhang; Yuda Yang; Yuyu Ren; Xiubao Sun; Yun Su; Yuhui Liu; et al. (Climatic Change, 2021)

Changing incidence and projections of thyroid cancer in mainland China, 1983–2032: evidence from Cancer Incidence in Five Continents - Mandi Li; Jiao Pei; Minghan Xu; Ting Shu; Chengjie Qin; Meijing Hu; Yawei Zhang; Min Jiang; Cairong Zhu (Cancer Causes & Control, 2021)

High nitrogen uptake and utilization contribute to the dominance of invasive Spartina alterniflora over native Phragmites australis - Qian-Wei Li; Xiao-Ya Zhang; Jin-Feng Liang; Jun-Qin Gao; Xing-Liang Xu; Fei-Hai Yu (Biology and Fertility of Soils, 2021)

Dietary selenium requirement of coho salmon (Oncorhynchus kisutch W.) alevins - Lian-cai Du; Hai-rui Yu; Ling-yao Li; Qin Zhang; Qi Tian; Jin-qian Liu; Ling-ling Shan (Aquaculture International, 2021)

Microorganism and Physiochemical Characteristic of High-salt (Suan Yu), a Traditional Chinese Fermented Fish - Chengxing Lin; Furong Zhang; Qin Yang; Ju Meng; Laping He; Li Deng; Chun Ye; Xuefeng Zeng (Journal of Aquatic Food Product Technology, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean - Xiaolong Fang; Xiaoyuan Sun; Xiangdong Yang; Qing Li; Chunjing Lin; Jie Xu; Wenjun Gong; Yifan Wang; Lu Liu; Limei Zhao; Baohui Liu; Jun Qin; et al. (Science China Life Sciences, 2021)

Effects of Vegetation Restoration on Soil Enzyme Activity in Copper and Coal Mining Areas - Hui Sun; Jianfeng Zhang; Rongjia Wang; Zongtai Li; Shiyong Sun; Guanghua Qin; Yumin Song (Environmental Management, 2021)

Metabolic pathway analysis of walnut endophytic bacterium Bacillus subtilis HB1310 related to lipid production from fermentation of cotton stalk hydrolysate based on genome sequencing - Qin Zhang; Panpan Liu; Yanbin Li; Hui Jiang (Biotechnology Letters, 2021)

Effects of ultrasound on functional properties, structure and glycation properties of proteins: a review - Derong Lin; Qiuting Zhang; Lijuan Xiao; Yichen Huang; Zhengfang Yang; Zhijun Wu; Zongcai Tu; Wen Qin; Hong Chen; Dingtao Wu; Qing Zhang; Suqing Li (Critical Reviews in Food Science and Nutrition, 2021)

An object-based graph model for unsupervised change detection in high resolution remote sensing images - Junzheng Wu; Biao Li; Yao Qin; Weiping Ni; Han Zhang (International Journal of Remote Sensing, 2021)

A Significant Genetic Admixture in Farmed Populations of the Noble Scallop Chlamys nobilis Revealed by Microsatellite DNA Analysis in Southern China - Haitao Ma; Dongmei Yu; Shu Xiao; Yanping Qin; Yang Zhang; Jun Li; Yuehuan Zhang; Ziniu Yu (Frontiers in Marine Science, 2021)
The noble scallop, Chlamys nobilis , is an important bivalve mollusk with high commercial value and is usually farmed in the waters of southern China. To date, very little is known about the genetic diversity and population structure of C. nobilis . In this study, 10 microsatellite loci of four farmed C. nobilis populations were compared with one another and compared wild population in southern China. A total of 83 alleles were found. Surprisingly, the level of genetic diversity of the farmed C. nobilis populations was higher than that of the wild population. Although the population genetic of wild population was completely in the Hardy–Weinberg equilibrium, due to heterozygote deficiency, significant deviations from the Hardy–Weinberg equilibrium were found in all farmed populations, suggesting a genetic admixture caused by the mixing of seeds from various hatcheries. The Fst and AMOVA values showed significant genetic differences between wild and farmed populations. The Bayesian assignment also confirmed that genetic admixture was significant and widespread in artificial breeding of C. nobilis . Furthermore, the UPGMA tree topology and PCA demonstrated that the genetic diversity of wild population can be clearly distinguished from farmed populations. In a nutshell, the findings of this study not only fill the knowledge gaps in genetic diversity of wild and farmed C. nobilis populations, but also serve as a guide for maintaining the genetic diversity of C. nobilis in both farmed and wild populations.

Enhanced Biodegradation of Hexachlorocyclohexane in Soil by Application of Exogenous Amendments - Xutong Liu; He Huang; Dan Huang; Kai Zhong; Qun Rong; Xingzi Qin; Chaolan Zhang; Xue Li (Water, Air, & Soil Pollution, 2021)

Proteomics provides individualized options of precision medicine for patients with gastric cancer - Wenwen Huang; Dongdong Zhan; Yazhuo Li; Nairen Zheng; Xin Wei; Bin Bai; Kecheng Zhang; Mingwei Liu; Xuefei Zhao; Xiaotian Ni; Xia Xia; Jinwen Shi; et al. (Science China Life Sciences, 2021)

The downregulation of PpPG21 and PpPG22 influences peach fruit texture and softening - Ming Qian; Ze Xu; Zehua Zhang; Qin Li; Xiangyan Yan; Hangkong Liu; Mingyu Han; Furui Li; Jicheng Zheng; Dong Zhang; Caiping Zhao (Planta, 2021)

Smad3 gene C-terminal phosphorylation site mutation exacerbates CCl4-induced hepatic fibrogenesis by promoting pSmad2L/C-mediated signaling transduction - Juan Yang; Yongfang Gong; Wenjing Xu; Lili Li; Zhenghao Shi; Qin Wang; Yinghao He; Chong Zhang; Chenchen Luo; Zhirui Fang; Yan Yang (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Prediction of landslide displacement using multi-kernel extreme learning machine and maximum information coefficient based on variational mode decomposition: a case study in Shaanxi, China - Qing Ling; Qin Zhang; Jing Zhang; Lingjie Kong; Weiqi Zhang; Li Zhu (Natural Hazards, 2021)

Evaluation of field resistance to brown stripe disease in novel and major cultivated sugarcane varieties in China - Xiao-Yan Wang; Xiao-Yan Cang; Wei Qin; Hong-Li Shan; Rong-Yue Zhang; Chang-Mi Wang; Wen-Feng Li; Ying-Kun Huang (Journal of Plant Pathology, 2021)

Occurrence and bioaccumulation of sulfonamide antibiotics in different fish species from Hangbu-Fengle River, Southeast China - Chunmeng Ye; Jiaqi Shi; Xuesheng Zhang; Li Qin; Zhongguan Jiang; Jinhua Wang; Yucheng Li; Bingxiang Liu (Environmental Science and Pollution Research, 2021)

Effect of diurnal temperature change on cardiovascular risks differed under opposite temperature trends - Pan Ma; Ying Zhang; Xinzi Wang; Xingang Fan; Lei Chen; Qin Hu; Shigong Wang; Tanshi Li (Environmental Science and Pollution Research, 2021)

Diversity and co-occurrence network modularization of bacterial communities determine soil fertility and crop yields in arid fertigation agroecosystems - Zhencheng Ye; Jing Li; Jie Wang; Chao Zhang; Guobin Liu; Qin’ge Dong (Biology and Fertility of Soils, 2021)

Petrophysical Texture Heterogeneity of Vesicles in Andesite Reservoir on Micro-Scales - Mutian Qin; Shuyun Xie; Jianbo Zhang; Tianfu Zhang; Emmanuel John M. Carranza; Hongjun Li; Jiayi Ma (Journal of Earth Science, 2021)

Development of CRISPR_Cas9 genome editing system and its application in rice molecular breeding - Zengfeng Ma; Minyi Wei; Yuexiong Zhang; Gang Qin; Chi Liu; Zhenjing Li; Dahui Huang (In Vitro Cellular & Developmental Biology - Plant, 2021)

Concentration determination of gold nanoparticles by flame atomic absorption spectrophotometry - Yuhong Fu; Quan Wan; Zonghua Qin; Shanshan Li; Sen Li; Ji Wang; Wei Zhang (Acta Geochimica, 2021)

A new ent -kaurane diterpene from Isodon henryi - Xue Jiang; Ling-Xia Zhang; Qing-Mei Feng; Hong Wu; Ya-Lin Liu; De-Qin Wang; Li-Ping Dai; Zhi-Min Wang (Natural Product Research, 2021)

Genetic Recombination of the Mantle Color Pattern of Two Boring Giant Clam (Tridacna crocea) Strains - Junjie Wang; Zihua Zhou; Haitao Ma; Jun Li; Yanping Qin; Jinkuan Wei; Xingyou Li; Qingliang Liao; Yunqing Li; Gongpengyang Shi; Yinyin Zhou; Yuehuan Zhang; et al. (Frontiers in Marine Science, 2021)
According to the RGB law display, the polymorphism of the giant clam mantle color pattern is through four iridocytes. The boring giant clam ( Tridacna crocea ) exhibits diverse mantle colors, including blue, green, purple, gold, and orange. In order to evaluate the genetic laws driving these mantle color patterns, a complete diallel cross between two color strains [blue strain (only blue iridocyte) and the yellow-green strain (yellow and green iridocytes)] was performed. Using a single-to-single mating system, two intra-strain crosses (BB and YY) and two reciprocal inter-strain crosses (BY and YB) were produced in triplicates. Higher fertilization rate and hatching rate were observed in all experimental groups, suggesting that there was no sperm–egg recognition barrier between the two strains. In the grow-out stage, the size of the reciprocal hybrids was larger than that of the two pure strains with a degree of heterosis. In addition, compared with the two pure strains, the hybrids have higher larval metamorphosis rate and higher survival rate. At 1 year of age, the mantle color pattern of pure strains showed 100% stable inheritance, while the reciprocal hybrids exhibited colorful patterns (a combination of blue, yellow, and green), suggesting that there was a genetic recombination of the mantle colors during the stable expression period. These results provide a theoretical basis for the formation of the mantle color of giant clam and its genetic segregation law, as well as provide guidance for genetic breeding of giant clams.

Utilizing multichannel electrical resistivity methods to examine the contributions of submarine groundwater discharges - Kun-kun Zhang; Xiu-jun Guo; Ning Li; Xi-qin Cui (Marine Georesources & Geotechnology, 2021)

Divergent Anatomical Correlates and Functional Network Connectivity Patterns in Temporal Lobe Epilepsy with and Without Depression - Yingjie Qin; Xin Tong; Wei Li; Le Zhang; Yingying Zhang; Xiuli Li; Jing Yang; Kun Qin; Du Lei; Qiyong Gong; Dong Zhou; Dongmei An (Brain Topography, 2021)

Establishment of an indirect ELISA-based method involving the use of a multiepitope recombinant S protein to detect antibodies against canine coronavirus - Yun-Feng Hao; Shao-Han Li; Guang-Zhi Zhang; Yi Xu; Guang-zong Long; Xiao-xiong Lu; Shang-Jin Cui; Tong Qin (Archives of Virology, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Identification, expression and enzyme activity of the group III sPLA 2 s in Cyprinus carpio L - Yuxin Xu; Hongxia Li; Dihui Xu; Jianlin Li; Fan Yu; Meiyao Wang; Qin Wang; Yunsheng Wu; Qiyuan Zhang; Yongkai Tang; Juhua Yu (Journal of Fish Biology, 2021)
Five group III secreted phospholipase (pla2g3s) homologous genes located on different linkage groups were identified from common carp ( Cyprinus carpio ), which we named Ccpla2g3a1 , Ccpla2g3a2 , Ccpla2g3b , Ccpla2g3c1 and Ccpla2g3c2 . The five genes encode 530, 525, 461, 752 and 753 amino acids, respectively. Sequence analysis showed that the Ccpla2g3a s contain seven exons and the others contain four exons. Synteny analysis of fish pla2g3s indicated that pla2g3a and pla2g3b were from the same ancestor gene, and Ccpla2g3a 1, Ccpla2g3a 2, Ccpla2g3c 1 and Ccpla2g3c 2 were from the specific genome duplication of common carp. Due to the significant variation of the pla2g3bs from common carp and zebrafish ( Danio rerio ), they formed a separate group in the phylogenetic tree. The tissue distributions of Ccpla2g3 s coincided with their expression profiles during the embryo stages. The expression levels of Ccpla2g3a s and Ccpla2g3c s were low at the embryo stages, and they were abundant in the liver and brain, respectively, whereas the expression of Ccpla2g3b was high at 0.5 h after fertilization and in the ovary. We obtained three soluble recombinant proteins of the bee venom‐like PLA2 (BVLP) from Ccpla2g3 and evaluated their PLA 2 enzyme properties. The optimum pHs of MBP‐a1‐BVLP, MBP‐b‐BVLP and MBP‐c1‐BVLP were 7.5, 7.0 and 8.0, respectively, and specific activities were 7.68 ± 0.66, 4.155 ± 0.158 and 1.93 ± 0.05 U μmol –1 , respectively. The K d for Ca 2+ of MBP‐b‐BVLP was the lowest (2.6 μM), whereas the values for both MBP‐a1‐BVLP and MBP‐c1‐BVLP were about 15 μM. The K m values of three proteins ranged from 31.9 to 41.91 μM.

Biochar Derived from Treated Lotus Stem and Adsorption of Phthalic Acid Esters - Ruiling Zhang; Linlin Chen; Binbin Qiu; Xiaojing Sun; Songyan Qin; Bo Wang; Feiyue Li; Lixin Zhao; Zhe Zhu (Water, Air, & Soil Pollution, 2021)

Fast and accurate detection of kiwifruit in orchard using improved YOLOv3-tiny model - Longsheng Fu; Yali Feng; Jingzhu Wu; Zhihao Liu; Fangfang Gao; Yaqoob Majeed; Ahmad Al-Mallahi; Qin Zhang; Rui Li; Yongjie Cui (Precision Agriculture, 2021)

Magnolol attenuates inflammatory pain by inhibiting sodium currents in mouse dorsal root ganglion neurons - Lu-lu Zhang; Jie Qiu; Jiang-ru Hong; Xiu-qi Xu; Guang-qin Zhang; Guang Li (Inflammopharmacology, 2021)

Phthalate exposure in association with the use of personal care products among general population from Shanghai - Jin Qin; Ruihua Dong; Min Wu; Yaqun Yuan; Han Zhang; Pai Meng; Meiru Zhang; Jingsi Chen; Shuguang Li; Bo Chen (Environmental Science and Pollution Research, 2021)

Disrupted pathways from frontal-parietal cortex to basal ganglia and cerebellum in patients with unmedicated obsessive compulsive disorder as observed by whole-brain resting-state effective connectivity analysis – a small sample pilot study - Wei Liu; Minghui Hua; Jun Qin; Qiuju Tang; Yunyi Han; Hongjun Tian; Daxiang Lian; Zhengqing Zhang; Wenqiang Wang; Chunxiang Wang; Ce Chen; Deguo Jiang; et al. (Brain Imaging and Behavior, 2021)

Erratum to: Spatio-temporal variation of Fraction of Photosynthetically Active Radiation absorbed by vegetation in the Hengduan Mountains, China - Zheng-lan Yang; Ting-bin Zhang; Gui-hua Yi; Jing-ji Li; Yan-bin Qin; Yang Chen (Journal of Mountain Science, 2021)

Paleoclimatic proxies from global closed basins and the possible beginning of Anthropocene - Yu Li; Qin Han; Lu Hao; Xinzhong Zhang; Dawei Chen; Yuxin Zhang; Lingmei Xu; Wangting Ye; Simin Peng; Yichan Li; Zhuowen Feng; Hebin Liu (Journal of Geographical Sciences, 2021)

Middle Triassic (Anisian) Conodont Biostratigraphy at the Shaiwa Section, Guizhou, South China - Binxian Qin; Martyn Lee Golding; Haishui Jiang; Yan Chen; Muhui Zhang; Li Kang; Dacheng Wang; Jinling Yuan (Journal of Earth Science, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Natural Climate Solutions for China: The Last Mile to Carbon Neutrality - Zhangcai Qin; Xi Deng; Bronson Griscom; Yao Huang; Tingting Li; Pete Smith; Wenping Yuan; Wen Zhang (Advances in Atmospheric Sciences, 2021)

Microbiome-Metabolomics Reveals Prebiotic Benefits of Fucoidan Supplementation in Mice - Jingyi Yuan; Song Qin; Wenjun Li; Yubing Zhang; Yuting Wang; Xiulian Chang; Lili Li (Journal of Marine Science and Engineering, 2021)
Fucoidan is a kind of polysaccharide with antitumor and antioxidant properties, which is mainly isolated from brown algae. Although there are many reports about the prebiotic effects of polysaccharides on hosts, there are few reports about the effects of fucoidan on blood biochemical indexes, intestinal microbiome, and metabolic function on healthy hosts. We applied 16S rRNA gene amplicon sequencing and LC-MS/MS metabolomics to evaluate the changes in the gut microbiome and metabolite profiles of fucoidan treatment in mice over 10 weeks. Fucoidan treatment modulated lipid metabolism, including significantly decreasing serum triglyceride level in healthy mice. Fucoidan also significantly inhibited serum lipopolysaccharide-binding protein (LBP) concentration, a biomarker of endotoxemia. Correlation analysis further showed that Lactobacillus animalis populations that were enriched by fucoidan demonstrated significantly negative correlations with serum triglyceride level. The abundance of Lactobacillus gasseri and Lactobacillus reuteri, increased by fucoidan supplementation, demonstrated significantly negative correlation with lipopolysaccharide-binding protein levels. Lactobacillus gasseri also demonstrated significantly positive correlations with three tryptophan-related metabolites, including indoleacrylic acid, 3-indoleacrylic acid, and 5-hydroxytryptamine, which were all increased by fucoidan administration. Combined with the previous evidence, the results indicate that fucoidan exerts prebiotic effects, such as lipid metabolism suppression and metabolic endotoxemia suppression, by modulating the abundance of gut microbiota, such as Lactobacillus animalis, Lactobacillus gasseri, and Lactobacillus reuteri, as well as microbiota-dependent metabolites, such as tryptophan-related metabolites.

Elucidating the Effect of Fine Lactose Ratio on the Rheological Properties and Aerodynamic Behavior of Dry Powder for Inhalation - Ying Sun; Lu Qin; Jiayi Li; Jian Su; Ruxiao Song; Xin Zhang; Jian Guan; Shirui Mao (The AAPS Journal, 2021)

Spatiotemporal variation of nitrogen and phosphorus and its main influencing factors in Huangshui River basin - Biqiong Dong; Tianling Qin; Yu Wang; Yan Zhao; Shanshan Liu; Jianming Feng; Chenhao Li; Xin Zhang (Environmental Monitoring and Assessment, 2021)
The foundation of managing excess nutrients in river is the identification of key physical processes and the control of decisive influencing factors. The existing studies seldom consider the influence of rainfall-runoff relationship and only focus on a few anthropogenic activities and natural attributes factors. To address this issue, a comprehensive set of influencing factors including rainfall-runoff relationship (represented by runoff coefficient), basic physical and chemical parameters of water quality, land use types, landscape patterns, topography, and socioeconomic development was constructed in this study. M–K test and cluster analysis were conducted to identify the temporal mutation and spatial clustering characteristics of NH 3 -N and TP in Huangshui River basin, respectively. Partial least squares regression was used to elucidate the linkages between water contaminants and the factors. As shown in the results, the temporal mutations of NH 3 -N and TP were obvious in the middle reaches, with 4 out of 7 catchments in the middle reaches have a larger number of mutations of NH 3 -N than other catchments. The cluster analysis results of NH 3 -N and TP among catchments were similar. This study also indicated that although the Huangshui River basin was located in the upper reaches of the Yellow River, the influences of rainfall-runoff relationship on spatiotemporal changes of NH 3 -N and TP in its sub-basins were limited. Only the temporal change of NH 3 -N in Jintan catchment in the upstream area was significantly affected by runoff coefficient. The indexes of proportion of water area (PWA), proportion of impervious area (PIA), and proportion of primary industry (PPI) were the top three influencing factors of temporal variation of NH 3 -N and TP for most catchments in the middle reaches. The temporal change of NH 3 -N in Jintan catchment in the upstream area was obviously affected by runoff coefficient. The spatial variation of NH 3 -N and TP were all affected by PWA and proportion of secondary industry significantly. The results of this study can provide theoretical basis and technical support for the control and management of nitrogen and phosphorus pollution in upper reaches of rivers.

Lithological and environmental controls on large tafoni along conglomerate cliffs in subtropic humid Danxiashan UNESCO Global Geopark - Xin Chen; Liu-qin Chen; Yan-hong Zhang; Ding-ding Du; Hai-ping Hu; Dong-xing Liu; Wen-zhuo Li (Journal of Mountain Science, 2021)

Influence of major water conservation projects on river channels and shorelines in the middle and lower reaches of the Yangtze River - Yue-hua Jiang; He-qin Cheng; Quan-ping Zhou; Yun Li; Guo-qiang Yang; Yang Jin; Shi-jia Mei; Xuan Gu; Hong Zhang (Arabian Journal of Geosciences, 2021)