Mechanisms of high ammonium loading promoted phosphorus release from shallow lake sediments: A five-year large-scale experiment - Shuo-Nan Ma; Yuan-Feng Xu; Hai-Jun Wang; Hong-Zhu Wang; Yan Li; Xu-Meng Dong; Ji-Lin Xu; Qing Yu; Martin Søndergaard; Erik Jeppesen (Water Research, 2023)

Inactivation of chlorine-resistant bacteria (CRB) via various disinfection methods: Resistance mechanism and relation with carbon source metabolism - Yu-Qing Xu; Yin-Hu Wu; Li-Wei Luo; Bang-Hao Huang; Zhuo Chen; Hao-Bin Wang; Han Liu; Nozomu Ikuno; Nakata Koji; Hong-Ying Hu (Water Research, 2023)

Overexpression of Sly-miR167a delayed postharvest chilling injury of tomato fruit under low temperature storage - Lei Li; Xuanqi Wang; Jieyu Lv; Wenhui Duan; Taishan Huang; Keyan Zhao; Lanhuan Meng; Hongmiao Song; Qing Wang; Xiangbin Xu; Jiangkuo Li (Postharvest Biology and Technology, 2023)

Effect of short-term ambient air pollution exposure on early miscarriage and pregnancy hormones with critical window identification - Qing Xu; Quanquan Guan; Yingying Lu; Jie Xu; Siting Deng; Chao Dong; Xiaochen Zhang; Wen Li; Yankai Xia (Journal of Hazardous Materials, 2023)

Association between urinary neonicotinoid insecticide levels and dyslipidemia risk: A cross-sectional study in Chinese community-dwelling elderly - Jian Sun; Pei He; Rui Wang; Zhong-Yuan Zhang; Yu-Qing Dai; Xiao-Yu Li; Si-Yu Duan; Cai-Ping Liu; Hao Hu; Guang-Jun Wang; Yan-Ping Zhang; Fei Xu; et al. (Journal of Hazardous Materials, 2023)

Molybdenum disulfide-loaded multilayer AuNPs with colorimetric-SERS dual-signal enhancement activities for flexible immunochromatographic diagnosis of monkeypox virus - Qing Yu; Jiaxuan Li; Shuai Zheng; Xuan Xia; Changyue Xu; Chaoguang Wang; Chongwen Wang; Bing Gu (Journal of Hazardous Materials, 2023)

High throughput, antibacterial and nonflammable melamine sponges for oil/water separation - Yu Li; Shusu Ren; Qing Yu; Tao Wang; Xiang Xu; Weiwei He; Lifen Zhang; Zhenping Cheng (Journal of Environmental Chemical Engineering, 2023)

Chalcogen-modified copper-nitrogen co-doped carbon as a stable and efficient antimicrobial cathode catalyst for microbial fuel cells - Bi-Lin Lai; Hai-Xia Liao; Shu-Qi Zhou; Hui-Xu Wei; Ai-Yi Li; Nan Li; Zhao-Qing Liu (Journal of Environmental Chemical Engineering, 2023)

Efficient removal of Cr(VI) from wastewater by ZnO-polyacrylic acid/cellulose fiber/polyethylene glycol hydrogel: Synergistic effect of adsorption and photocatalytic reduction - Qing Li; Xiaojie Zhuang; Guanhong Zhou; Zhenfei Yang; Ting Yang; Hongbo Xiao; Tao Xu; Wenlei Wang (Journal of Environmental Chemical Engineering, 2023)

A bispecific nanobody with high sensitivity/efficiency for simultaneous determination of carbaryl and its metabolite 1-naphthol in the soil and rice samples - Min-ling Liu; Zi-jian Chen; Xiao-qing Huang; Hong Wang; Jin-li Zhao; Yu-dong Shen; Lin Luo; Xiao-wei Wen; Bruce Hammock; Zhen-lin Xu (Environmental Pollution, 2023)

Long-term detraining reverses the improvement of lifelong exercise on skeletal muscle ferroptosis and inflammation in aging rats: fiber-type dependence of the Keap1/Nrf2 pathway - Zhuang-Zhi Wang; Hai-Chen Xu; Huan-Xia Zhou; Chen-Kai Zhang; Bo-Ming Li; Jia-Han He; Pin-Shi Ni; Xiao-Ming Yu; Yun-Qing Liu; Fang-Hui Li (Biogerontology, 2023)

Complete Genome Sequence of Streptomyces sp. HP-A2021, a Promising Bacterium for Natural Product Discovery - Lan-Fang Li; Qing-Xuan Wu; Hao Wu; Yao Li; Qian Peng; Ren-Hao Han; Da-Hu Zhang; Wei-Dong Yu; Rui Xu; Juan Wang; Zhaobin Fan; Shao-Yang Hou (Biochemical Genetics, 2023)

Diverse diterpenoids from Callicarpa rubella Lindl. as natural inhibitors of macrophage foam cell formation - Xue-Wen Wu; Qian-Lang Feng; Yi-Fan Xie; Si-Chen Song; Bin Cheng; Yan Ma; Qing Li; Xu Ji; Xiao-Li Li; Guang Cao; Wei-Lie Xiao (Phytochemistry, 2023)

Revealing the mechanism underlying the effects of γ-aminobutyric acid-dioscorin interactions on dioscorin structure and emulsifying properties by molecular dynamic simulations - Yun-long Chen; Hao-nan Nie; Hui Dong; Qi Gao; Xue Peng; Ning Wang; Xueling Chen; Qing-zheng Liu; Jiang-kuo Li; Xiang-bin Xu; You-lin Xue (Food Research International, 2023)

The effect of BVOCs produced by Lysinibacillus fusiformis and LED irradiation on pigment metabolism in stored broccoli - Junyan Shi; Taishan Huang; Ying Zhang; Zengting Xing; Xiaozhen Yue; Shuzhi Yuan; Hua Li; Xiangbin Xu; Jinhua Zuo; Qing Wang (Food Chemistry, 2023)

Performance and mechanism of calcium peroxide reducing H2S production from sludge anaerobic fermentation - Yunhao Xu; Qizi Fu; Wenming Wang; Fan Yang; Xuemei Li; Fengming Song; Yanguang Qing; Ziqi Lin; Weiqi Long; Dongbo Wang (Chemical Engineering Journal, 2023)

Design of amphoteric micro/nanofiber-coupling fabric for ultrafast, precise, and robust removal of water droplets from oils - Chenglong Li; Cai Long; Yang Cai; Zhaohang Li; Ziyu Guan; Haoyang Song; Lu Guo; Xinyu Xu; Changsheng Liu; Yongquan Qing (Chemical Engineering Journal, 2023)

Catechol-chitosan/carboxymethylated cotton-based Janus hemostatic patch for rapid hemostasis in coagulopathy - Qian Xu; Enling Hu; Haoyu Qiu; Lu Liu; Qing Li; Bitao Lu; Kun Yu; Fei Lu; Ruiqi Xie; Guangqian Lan; Yuansong Zhang (Carbohydrate Polymers, 2023)

Prediction of landslide block movement based on Kalman filtering data assimilation method - Yong Liu; Qing-jie Xu; Xing-rui Li; Ling-feng Yang; Hong Xu (Journal of Mountain Science, 2023)

Age- and gender-related dispersion of brain networks across the lifespan - Qing Wang; Lingyu Qi; Cancan He; Haixia Feng; Chunming Xie; Chao-Gan Yan; Xiao Chen; Le Li; Francisco Xavier Castellanos; Tong-Jian Bai; Ning-Xuan Chen; Wei Chen; et al. (GeroScience, 2023)

Investigation of the peak punch-through capacity of spudcan on sand overlying spatially variable clay - Jiang Tao Yi; Shi Jie Xu; Xiao Bin Li; Qing Shan Yang; Si Yu Li (Ocean Engineering, 2023)

Structure-guided camera localization for indoor environments - Qing Li; Rui Cao; Kanglin Liu; Zongze Li; Jiasong Zhu; Zhenyu Bao; Xu Fang; Qingquan Li; Xianfeng Huang; Guoping Qiu (ISPRS Journal of Photogrammetry and Remote Sensing, 2023)

Effects of linking group on the desalination performance of three-dimensional covalent organic framework membranes - Mengjiao Guan; Qingzhi Liu; Huiting Zhang; Qing Li; Jianan Xu; Mengmeng Cai; Weike Lin; Weina Li; Dengfeng Yang (Desalination, 2023)

AIWW: a new nutrition-screening tool for the oncologic population - Yi-Zhong Ge; Zhen-Ming Fu; Qi Zhang; Meng-Meng Song; Guo-Tian Ruan; Xi Zhang; Xiao-Wei Zhang; Xiang-Rui Li; Kang-Ping Zhang; Meng Tang; Xiao-Yue Liu; Ming Yang; et al. (Science China Life Sciences, 2023)

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions - He-Wei Jiang; Hong Chen; Yun-Xiao Zheng; Xue-Ning Wang; Qingfeng Meng; Jin Xie; Jiong Zhang; ChangSheng Zhang; Zhao-Wei Xu; Zi-Qing Chen; Lei Wang; Wei-Sha Kong; et al. (Science China Life Sciences, 2023)

Mucilage secretion by aerial roots in sorghum (Sorghum bicolor): sugar profile, genetic diversity, GWAS and transcriptomic analysis - Si Xu; Xiu-Qing Li; Hong Guo; Xiao-Yuan Wu; Ning Wang; Zhi-Quan Liu; Huai-Qing Hao; Hai-Chun Jing (Plant Molecular Biology, 2023)

The fate of carbon resulting from pore water exchange in a mangrove and Spartina alterniflora ecozone - Weizhen Jiang; Guizhi Wang; Qing Li; Manab Kumar Dutta; Shilei Jin; Guiyuan Dai; Yi Xu (Acta Oceanologica Sinica, 2023)

Coupled anaerobic methane oxidation and metal reduction in soil under elevated CO 2 - Chenchao Xu; Naifang Zhang; Kaihang Zhang; Shuyao Li; Qing Xia; Jing Xiao; Maojun Liang; Weilei Lei; Junpan He; Gaiping Chen; Chengjun Ge; Xunhua Zheng; et al. (Global Change Biology, 2023)
Continued current emissions of carbon dioxide (CO 2 ) and methane (CH 4 ) by human activities will increase global atmospheric CO 2 and CH 4 concentrations and surface temperature significantly. Fields of paddy rice, the most important form of anthropogenic wetlands, account for about 9% of anthropogenic sources of CH 4 . Elevated atmospheric CO 2 may enhance CH 4 production in rice paddies, potentially reinforcing the increase in atmospheric CH 4 . However, what is not known is whether and how elevated CO 2 influences CH 4 consumption under anoxic soil conditions in rice paddies, as the net emission of CH 4 is a balance of methanogenesis and methanotrophy. In this study, we used a long‐term free‐air CO 2 enrichment experiment to examine the impact of elevated CO 2 on the transformation of CH 4 in a paddy rice agroecosystem. We demonstrate that elevated CO 2 substantially increased anaerobic oxidation of methane (AOM) coupled to manganese and/or iron oxides reduction in the calcareous paddy soil. We further show that elevated CO 2 may stimulate the growth and metabolism of Candidatus Methanoperedens nitroreducens , which is actively involved in catalyzing AOM when coupled to metal reduction, mainly through enhancing the availability of soil CH 4 . These findings suggest that a thorough evaluation of climate‐carbon cycle feedbacks may need to consider the coupling of methane and metal cycles in natural and agricultural wetlands under future climate change scenarios.

Determinants affecting the blood mercury levels of preschool children in Shanghai, China: A cross-sectional study - Xi Xu; Yu-Qing Wang; Chen-Yin Dong; Chun-Ping Hu; Li-Na Zhang; Zhen-Yan Gao; Min-Ming Li; Su-Su Wang; Chong-Huai Yan (Environmental Science and Pollution Research, 2023)

Novel fatty acids-governed cannibalism in beneficial rhizosphere Bacillus enhances biofilm formation via a two-component system OmpS/R and toxin transporter - Rong Huang; Qing Li; Dandan Wang; Haichao Feng; Nan Zhang; Jiahui Shao; Qirong Shen; Zhihui Xu; Ruifu Zhang (Science Bulletin, 2023)

Highly oxygenated germacrane-type sesquiterpenoids from the whole plant of Salvia cavaleriei H.Lév. and their biological activities - Xiao-Han Chen; Xu Liu; Wen-Bo Cui; Feng-Li An; Li Liu; Qian Wu; Jian-Ning Yu; Jian-Ye Dai; Zhan-Xin Zhang; Dong-Qing Fei (Phytochemistry, 2023)

Punching shear behavior and strength prediction of UHTCC-enhanced RC slab-column joints - Xiao-Ning Huang; Qing-Hua Li; Jing-Zhong Tong; Shi-Lang Xu; Yu-Chen Lu (Engineering Structures, 2023)

Methane distribution and sea-to-air methane flux in the Dongsha area of the South China Sea - Cuiling Xu; Zhilei Sun; Qing Li; Xianrong Zhang; Xilin Zhang; Bin Zhai; Qiang Fu; Yuhai Sun; Wei Geng; Hong Cao; Ye Chen; Nengyou Wu (Continental Shelf Research, 2023)

Investigating the thermal conductivity and flame-retardant properties of BN/MoS2/PCNF composite film containing low BN and MoS2 nanosheets loading - Lei Yang; Wei Xu; Xiaolong Shi; Menglin Wu; Ziyi Yan; Qing Zheng; Gongneng Feng; Li Zhang; Rong Shao (Carbohydrate Polymers, 2023)

Characterization of iron, sulfur, and phosphorus diagenesis in muddy sediments of the South Yellow Sea using the diffusive gradients in thin films (DGT) technique - Zhen Xu; Wen-Xuan Sun; Qing-Qing Li; Ying-Jian Han; Wei-Wei Ma; Tie Li; Mao-Xu Zhu (Aquatic Sciences, 2023)

Real-time perception of rock–machine interaction information in TBM tunnelling using muck image analysis - Wei-Qiang Xie; Xiao-Ping Zhang; Xiao-Li Liu; Chen-Yu Xu; Xin-Fang Li; Dan-Qing Song; Qing Ma; Nan Hu (Tunnelling and Underground Space Technology, 2023)

Long-term cadmium exposure induces chronic obstructive pulmonary disease-like lung lesions in a mouse model - Wen-Jing Wang; Kun Peng; Xue Lu; Yan-Yan Zhu; Zhao Li; Qing-Hua Qian; Ya-Xin Yao; Lin Fu; Yan Wang; Yi-Chao Huang; Hui Zhao; Hua Wang; et al. (Science of The Total Environment, 2023)

Global association of greenness exposure with risk of nervous system disease: A systematic review and meta-analysis - Fangzheng Li; Wei Liu; Chengyang Hu; Mingcheng Tang; Yunquan Zhang; Hung Chak Ho; Shijia Peng; Zhouyuan Li; Qing Wang; Xiong Li; Bing Xu; Fengyi Li (Science of The Total Environment, 2023)

Extending the record of dolabellane-type diterpenoids from the soft coral Clavularia viridis: Structures and stereochemistry - Ye-Qing Du; Yuan Gao; Yi Zang; Jia Li; Xu-Wen Li; Yue-Wei Guo (Phytochemistry, 2023)

Site-directed transformants with E407K substitution in Bcmdl1 possesses different fitness from field anilinopyrimidine resistant isolates with E407K mutation in Botrytis cinerea - Fei Fan; Ming-Yi Wu; Yong-Xu Zhu; Guo-Qing Li; Chao-Xi Luo (Pesticide Biochemistry and Physiology, 2023)

Removal of Zn2+ from glycolytic monomers of the polyethylene terephthalate based on electrodeposition - Wenxia Hou; Yi Li; Shuting Xu; Qian Wang; Kuntong Song; Junhong Liu; Nan Wang; Qing Zhou; Dongxia Yan; Xingmei Lu (Journal of Environmental Chemical Engineering, 2023)

Gestational cadmium exposure disrupts fetal liver development via repressing estrogen biosynthesis in placental trophoblasts - Yi-Ting Fu; Jin Zhang; Wei-Bo Liu; Yu-Feng Zhang; Shuang Zhang; Lu-Lu Tan; Qing Lin; Kong-Wen Ou-Yang; Yong-Wei Xiong; Wei Chang; Hao Li; Jun-Ying Yu; et al. (Food and Chemical Toxicology, 2023)

Rapid identification of high and low cadmium (Cd) accumulating rice cultivars using machine learning models with molecular markers and soil Cd levels as input data - Zhong Tang; Ting-Ting You; Ya-Fang Li; Zhi-Xian Tang; Miao-Qing Bao; Ge Dong; Zhong-Rui Xu; Peng Wang; Fang-Jie Zhao (Environmental Pollution, 2023)

RETRACTED ARTICLE: RAD54L promotes progression of hepatocellular carcinoma via the homologous recombination repair pathway - Hongda Li; Haiwen Zhuang; Tengfei Gu; Guangyu Li; Yuhang Jiang; Sanrong Xu; Qing Zhou (Functional & Integrative Genomics, 2023)

Methane emission reduction oriented extracellular electron transfer and bioremediation of sediment microbial fuel cell: A review - Chong Xu; Shiquan Sun; Yifu Li; Yang Gao; Wei Zhang; Liu Tian; Tian Li; Qing Du; Jingju Cai; Lean Zhou (Science of The Total Environment, 2023)

Norgestrel causes digestive gland injury in the clam Mactra veneriformis: An integrated histological, transcriptomics, and metabolomics study - Xiaoran Zhao; Qing Wang; Xiangfei Li; Hua Xu; Chuanbo Ren; Yanyan Yang; Shuhao Xu; Guoxing Wei; Yujun Duan; Zhitao Tan; Yan Fang (Science of The Total Environment, 2023)

Iron geochemistry in surface sediments of the subtropical northern South China Sea and a comparison with the temperate East China Sea - Ying-Jian Han; Jian-Hua Ren; Qing-Qing Li; Wen-Xuan Sun; Tie Li; Mao-Xu Zhu (Journal of Marine Systems, 2023)

Deciphering mantle heterogeneity associated with ancient subduction-related metasomatism: Insights from Mg-K isotopes in potassic alkaline rocks - Zhuang Miao; Xiaoqiang Li; Zhidan Zhao; Yaoling Niu; Bo Xu; Hangshan Lei; Jingkai Wu; Yiyun Yang; Qian Ma; Dong Liu; Qing Wang; Di-Cheng Zhu; et al. (Geochimica et Cosmochimica Acta, 2023)

Adenosine triphosphate induced transition-metal phosphide nanostructures encapsulated with N, P-codoped carbon toward electrochemical water splitting - Peng Wei; Xueping Sun; Zhimin He; Fangyuan Cheng; Jia Xu; Qing Li; Yurong Ren; Jianhua He; Jiantao Han; Yunhui Huang (Fuel, 2023)

Machine learning based age-authentication assisted by chemo-kinetics: Case study of strong-flavor Chinese Baijiu - Qing-Ru Liu; Xiao-Juan Zhang; Lei Zheng; Lian-Jun Meng; Guang-Qian Liu; Ting Yang; Zhen-Ming Lu; Li-Juan Chai; Song-Tao Wang; Jin-Song Shi; Cai-Hong Shen; Zheng-Hong Xu (Food Research International, 2023)

Multiple biological activities and biosynthesis mechanisms of specific conjugated linoleic acid isomers and analytical methods for prospective application - Suhong Li; Liangwei Xu; Junjun Qing; Xiaodan Wu; Haixing Li; Hongbing Chen; Xiaohua Liu (Food Chemistry, 2023)

Effects of spray drying and freeze drying on the structure and emulsifying properties of yam soluble protein: A study by experiment and molecular dynamics simulation - Hao-nan Nie; Hui Dong; Yun-long Chen; Miao-miao Hao; Jia-nan Chen; Zi-cheng Tang; Qing-zheng Liu; Jiang-kuo Li; Xiang-bin Xu; You-lin Xue (Food Chemistry, 2023)

Assembly of zein/propylene glycol alginate nanoparticles in aqueous ethanol and the binding kinetics - Yang Yu; Shi-Yu Li; Tong-Cheng Xu; Guo-Qing Huang; Jun-Xia Xiao (Food Hydrocolloids, 2023)

Rolling flexible double-MXenes TiCT/VCT hybrid films for microsupercapacitors - Shuaikai Xu; Hongpeng Yang; Yubing Li; Haifu Huang; Xianqing Liang; Yuanhao Wang; Qing Hu; Guodong Wei; Ya Yang (Chemical Engineering Journal, 2023)

Developments of efficient dithionite-zerovalent iron/persulfate systems with accelerated Fe(III)/Fe(II) cycle for PAHs removal in water and soils - Maolin Wang; Yaling Wang; Xudong Jing; Jiahui Xu; Min Li; Qing Xie; Xiyun Cai (Chemical Engineering Journal, 2023)

Urea impregnation into fungus pretreated corn stover to perform pyrolysis for production of nitrogen-containing bio-oil and nitrogen-doped biochar - Zhenjie Sun; Shanjian Liu; Yue Xu; Jingqi Lu; Hao Shi; Songlin Li; Chuping Luo; Qing Dong (Bioresource Technology, 2023)

Biomarkers of aging - Hainan Bao; Jiani Cao; Mengting Chen; Min Chen; Wei Chen; Xiao Chen; Yanhao Chen; Yu Chen; Yutian Chen; Zhiyang Chen; Jagadish K. Chhetri; Yingjie Ding; et al. (Science China Life Sciences, 2023)

Biphasic Cholinergic Modulation of Reverberatory Activity in Neuronal Networks - Xiao-Wei Li; Yi Ren; Dong-Qing Shi; Lei Qi; Fang Xu; Yanyang Xiao; Pak-Ming Lau; Guo-Qiang Bi (Neuroscience Bulletin, 2023)
Acetylcholine (ACh) is an important neuromodulator in various cognitive functions. However, it is unclear how ACh influences neural circuit dynamics by altering cellular properties. Here, we investigated how ACh influences reverberatory activity in cultured neuronal networks. We found that ACh suppressed the occurrence of evoked reverberation at low to moderate doses, but to a much lesser extent at high doses. Moreover, high doses of ACh caused a longer duration of evoked reverberation, and a higher occurrence of spontaneous activity. With whole-cell recording from single neurons, we found that ACh inhibited excitatory postsynaptic currents (EPSCs) while elevating neuronal firing in a dose-dependent manner. Furthermore, all ACh-induced cellular and network changes were blocked by muscarinic, but not nicotinic receptor antagonists. With computational modeling, we found that simulated changes in EPSCs and the excitability of single cells mimicking the effects of ACh indeed modulated the evoked network reverberation similar to experimental observations. Thus, ACh modulates network dynamics in a biphasic fashion, probably by inhibiting excitatory synaptic transmission and facilitating neuronal excitability through muscarinic signaling pathways.

Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis - Jin Chen; Li Xu; Xue-Qing Zhang; Xue Liu; Zi-Xuan Zhang; Qiu-Mei Zhu; Jian-Yu Liu; Muhammad Omer Iqbal; Ning Ding; Chang-Lun Shao; Mei-Yan Wei; Yu-Chao Gu (Marine Life Science & Technology, 2023)
Non-alcoholic steatohepatitis (NASH) is a primary cause of cirrhosis and hepatocellular carcinoma. Unfortunately, there is no approved drug treatment for NASH. AMP-activated kinase (AMPK) is an important metabolic sensor and whole-body regulator. It has been proposed that AMPK activators could be used for treating metabolic diseases such as obesity, type 2 diabetes and NASH. In this study, we screened a marine natural compound library by monitoring AMPK activity and found a potent AMPK activator, candidusin A ( CHNQD-0803 ). Further studies showed that CHNQD-0803 directly binds recombinant AMPK with a K D value of 4.728 × 10 –8 M and activates AMPK at both molecular and intracellular levels. We then investigated the roles and mechanisms of CHNQD-0803 in PA-induced fat deposition, LPS-stimulated inflammation, TGF-β-induced fibrosis cell models and the MCD-induced mouse model of NASH. The results showed that CHNQD-0803 inhibited the expression of adipogenesis genes and reduced fat deposition, negatively regulated the NF-κB-TNFα inflammatory axis to suppress inflammation, and ameliorated liver injury and fibrosis. These data indicate that CHNQD-0803 as an AMPK activator is a novel potential therapeutic candidate for NASH treatment.

Triassic granitoids in the East Kunlun Orogenic Belt, Northwestern China: magmatic source and implications for geodynamic evolution - Zhi-He Xu; Wei Xin; Xiao-Dong Zhou; Qing-Lin Xu; Fu-Wen Li; Zhao-Jun Song (International Geology Review, 2023)

Retrieving leaf area index from FY-3D MERSI-II data using a sensor-adaptive algorithm - Yepei Chen; Pengfei Li; Chuan Xu; Zhina Song; Kaimin Sun; Wenzhuo Li; Xiuqing Hu; Qing An (International Journal of Remote Sensing, 2023)

Advances and challenges in interaction between heteroglycans and Bifidobacterium: Utilization strategies, intestinal health and future perspectives - Long-Qing Li; Xu Chen; Jie Zhu; Shuyan Zhang; Si-Qian Chen; Xiaozhen Liu; Lin Li; Jing-Kun Yan (Trends in Food Science & Technology, 2023)

Harnessing data assimilation and spatial autocorrelation for forest inventory - Qing Xu; Bo Li; Ronald E. McRoberts; Zengyuan Li; Zhengyang Hou (Remote Sensing of Environment, 2023)

Knockdown of Sly-miR160a using short tandem target mimic (STTM) enhanced expression of auxin signaling genes and delayed postharvest ripening of tomato fruit - Francine Ngaffo Mekontso; Shuhui Wu; Ruizuo Fu; Wen Li; Lanhuan Meng; Qing Wang; Jiangkuo Li; Hongmiao Song; Xiangbin Xu (Postharvest Biology and Technology, 2023)

JA-induced TaMPK6 enhanced the freeze tolerance of Arabidopsis thaliana through regulation of ICE-CBF-COR module and antioxidant enzyme system - Meng-Meng Yu; Rui Wang; Jing-Qiu Xia; Chang Li; Qing-Hua Xu; Jing Cang; Yu-Ying Wang; Da Zhang (Plant Science, 2023)

Bimetal Cu and Fe modified g-C3N4 sheets grown on carbon skeleton for efficient and selective photocatalytic reduction of CO2 to CO - Songyuan Bian; Xueyan Li; Long Zhang; Libin Wang; Jingzhen Wang; Qing Xu; Linlin Zang; Yanhong Zhang; Liguo Sun (Journal of Environmental Chemical Engineering, 2023)

One-step extraction and solidification of uranium (VI) from sulfate leaching liquor using bifunctional ionic liquids - Fang Zhang; Qiang Wu; Jia-Xuan Yan; Lei-Tao Sha; Yang Li; Xu-Xin Li; Qing-Gang Huang; Ze-Yi Yan (Journal of Environmental Chemical Engineering, 2023)

An investigation into the modification of microwave-assisted oxidation in the macromolecular structure of coal via XRD and Raman spectroscopy - Chaoping Xu; He Li; Jiexin Lu; Yi Lu; Shiliang Shi; Qing Ye; Min Li; Zheng Wang (Fuel, 2023)

Effect of flavonoids and CYP3A4 variants on midostaurin metabolism - Ren-ai Xu; Qing-qing Li; Nan-yong Gao; Jing Wang; Xin-yue Li; Feng Ye; Jin-huan Ni; Guo-xin Hu; Jian-chang Qian (Food and Chemical Toxicology, 2023)

Pre- and postnatal particulate matter exposure and blood pressure in children and adolescents: A systematic review and meta-analysis - Yufan Liu; Yan Li; Hailin Xu; Xinying Zhao; Yawen Zhu; Bosen Zhao; Qing Yao; Huawei Duan; Caixia Guo; Yanbo Li (Environmental Research, 2023)

Experimental study on flexural performance of steel-UHTCC composite bridge decks considering different shear connection degrees - Jing-Zhong Tong; Yun-Long Chen; Qing-Hua Li; Shi-Lang Xu; Tian Zeng; Wei Gao (Engineering Structures, 2023)

A Refined Extraction Method for Street Trees in Mobile Laser System Point Clouds - Yong Zhou; Rufei Liu; Hui Qi; Bori Cong; Jiamiao Xu; Minye Wang; Qing-ying Li (Journal of the Indian Society of Remote Sensing, 2023)

Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway - Xiao-Hui Niu; Rong-Hua Liu; Xiao Lv; Rui-Lin He; Fang-Zhou Lv; Shu-Jie Wu; Xu-Qing Li; Lei Li; Jia-Feng Lin (Inflammation Research, 2023)

Ecotoxicity stress and bioaccumulation in Eisenia fetida earthworms exposed to vanadium pentoxide in soil - Shi-qing Zhao; Hong Ni; Ji Li; Shun-hao Ai; Xiao-nan Wang; Xiang-yun Gao; Qian-yun Xu; Zheng-tao Liu (Environmental Science and Pollution Research, 2023)

Sources, chemical components, and toxicological responses of size segregated urban air PM samples in high air pollution season in Guangzhou, China - Mo Yang; Hui-Xian Zeng; Xin-Feng Wang; Henri Hakkarainen; Ari Leskinen; Mika Komppula; Marjut Roponen; Qi-Zhen Wu; Shu-Li Xu; Li-Zi Lin; Ru-Qing Liu; Li-Wen Hu; et al. (Science of The Total Environment, 2023)

The compositional characteristics, influencing factors, effects on wine quality and relevant analytical methods of wine polysaccharides: A review - Hong-Yue Zhai; Si-Yu Li; Xu Zhao; Yi-Bin Lan; Xin-Ke Zhang; Ying Shi; Chang-Qing Duan (Food Chemistry, 2023)

Biological magnetic ion exchange resin on advanced treatment of synthetic wastewater - Shanshan Xu; Yunbao Yan; Chendong Shuang; Qing Zhou; Rong Ji; Aimin Li (Bioresource Technology, 2023)

Depth-Dependent Controls Over Soil Organic Carbon Stock across Chinese Shrublands - Jielin Ge; Wenting Xu; Gaoming Xiong; Changming Zhao; Jiaxiang Li; Qing Liu; Zhiyao Tang; Zongqiang Xie (Ecosystems, 2023)

rTFPI Protects Cardiomyocytes from Hypoxia/Reoxygenation Injury through Inhibiting Autophagy and the Class III PI3K/Beclin-1 Pathway - Runan Yan; Wei Gao; Wenjia Chen; Yue Liu; Li Shen; Yue Dai; Rui Xu; Qing Chang; Yu Fu; Yong Zhao (Cell Biochemistry and Biophysics, 2023)

Comparative cytotoxicity, endocrine-disrupting effects, oxidative stress of halophenolic disinfection byproducts and the underlying molecular mechanisms revealed by transcriptome analysis - Xiuwen Li; Xinran Gao; Aimin Li; Shuhui Xu; Qing Zhou; Lulu Zhang; Yang Pan; Wei Shi; Maoyong Song; Peng Shi (Water Research, 2023)

An antioxidant lignan glycoside and triterpenoid saponins from the leaves of Synsepalum dulcificum - Xin-Peng Li; Jun-Fei Wang; Rong Huang; Tang-Chang Xu; Si-Si Liu; Qing-Rong Yang; Shao-Hua Wu (Phytochemistry Letters, 2023)

The preparation of PANI-doped Co-Ni-ZIF carbonized derivatives and the exploration of EET process by the DFT calculation and the prediction of related functional genes - Xu Pan; Fei Li; Ye Chen; Qing Wen; Xiaoqian Li; Junhong Wang; Haitao Xu; Liuqingying Yang (Fuel, 2023)

Synergy of yolk-shelled structure and tunable oxygen defect over CdS/CdCO3-CoS2: Wide band-gap semiconductors assist in efficient visible-light-driven H2 production and CO2 reduction - Siyi Zhang; Shiwen Du; Yumin Wang; Ziwu Han; Xu Li; Guojun Li; Qing Hu; Hu Xu; Chunqing He; Pengfei Fang (Chemical Engineering Journal, 2023)

Short-Term Limited Water Irrigation Influences the Photosynthetic Pigments, Enzymatic and Non-Enzymatic Activities in Saccharum spontaneum L. at Vegetative Stage - Zhi-Nian Deng; Hai-Rong Huang; Cheng-Mei Huang; Krishan K. Verma; Hai-Bin Luo; Sheng-Li Jiang; Yi-Jie Li; Hui-Qing Cao; Kai-Chao Wu; Lin Xu (Sugar Tech, 2023)

Effects of Acidification on the Wettability Modification of Coal and Adsorption Characteristics of Coalbed Methane - Rui Zhang; Mei Yuan; Bobo Li; Zhaoping Li; Qing Lv; Shiqing Xu (Natural Resources Research, 2023)

Late Holocene glacier variations indicated by the δ18O of ice core enclosed gaseous oxygen in the central Tibetan Plateau - Jiu-le Li; Bai-qing Xu; Ning-lian Wang; Ping Yao; Xiang-ke Xu (Journal of Mountain Science, 2023)

Effects of bepridil on early cardiac development of zebrafish - Ya-Lan Wei; Yu-Qing Lei; Zhou-Jie Ye; Xu-Dong Zhuang; Li-Ping Zhu; Xin-Rui Wang; Hua Cao (Cell and Tissue Research, 2023)

CRISPR-based DNA methylation editing of NNT rescues the cisplatin resistance of lung cancer cells by reducing autophagy - Chi Xu; Shuyun Jiang; Xingyu Ma; Zeyong Jiang; Youguang Pan; Xiang Li; Liying Zhang; Hao Zhou; Shen Chen; Xiumei Xing; Liping Chen; Wenfan Fu; et al. (Archives of Toxicology, 2023)

Effects of single or conjoint administration of lactic acid bacteria as potential probiotics on the growth, immune responses, and disease resistance of Carassius auratus - Ruoming Li; Teng Chi; Qing Xu; Juntong Liu; Xiaofeng Shan; Rui Zhou; Jiayun Yao; Wuwen Sun; Guiqin Wang (Aquaculture International, 2023)

Black soldier fly larvae replace traditional iced trash fish diet to enhance the delicious flavor of Chinese mitten crab (Eriocheir sinensis) - Jian-Feng Qiu; Cheng Luo; Li-Hua Ren; Wei Li; Tai-Ming Dai; Guang Wang; Xiao-Ning Sun; Kou-Chang Chong Moua; Yang-Hu Sima; Shi-Qing Xu (Frontiers in Marine Science, 2023)
Chinese mitten crabs ( Eriocheir sinensis ) are traditionally fed iced trash fish, but the industry is facing problems such as low breeding safety. Black soldier fly ( Hermetia illucens ) is an alternative protein source in animal diets, including diets for aquatic animals, due to its high nutritional value. However, studies on the effects of black soldier fly on the flavor characteristics of aquatic animals are still limited. In the present study, we investigated the effects of the complete replacement of iced trash fish with black soldier fly larvae during the fattening period of Chinese mitten crab on the flavor molecule contents and evaluation indices. The levels of free amino acids and nucleotides were determined in three edible parts (muscle, hepatopancreas, and gonads) of crab. Taste activity value analysis showed that glutamic acid, glycine, alanine, and arginine were the main amino acids contributing to the umami taste and sweetness, while histidine, lysine, valine, and methionine were the main amino acids contributing to the bitterness. Equivalent umami concentration (EUC) analysis showed that female gonads had the strongest umami taste, followed by the hepatopancreas and muscle. Sweetness value (SWT) analysis showed that the sweetness of muscle was the highest. Feeding black soldier fly larvae affected the flavor characteristics of crabs with tissue and sex differences. The EUC of the female gonads and SWT of the muscle were significantly increased. Meanwhile, the EUC of the hepatopancreas and SWT of the gonads were slightly decreased in male crabs. Our results indicate that the complete replacement of iced trash fish with black soldier fly larvae during the fattening period significantly enhances the flavor characteristics of crabs based on the contents of flavoring amino acids and nucleotides. It is important for sustainable aquaculture to replace animal protein with alternative protein sources such as black soldier fly larvae.

Investigation of zeolite H-β effect on pyrolysis of polystyrene by multiple kinetic analysis methods - Qing-yuan Ma; Zhen Huang; Yu-si Li; Chen-xu Zhao (Environmental Science and Pollution Research, 2023)

Water microecology is affected by seasons but not sediments: A spatiotemporal dynamics survey of bacterial community composition in Lake Changshou—The largest artificial lake in southwest China - Ai-ling Chen; Fu-qing Xu; Xia Su; Fu-pan Zhang; Wan-chao Tian; Shang-jie Chen; Fang Gou; Zhi-lin Xing; Jin-xin Xiang; Juan Li; Tian-tao Zhao (Marine Pollution Bulletin, 2023)

ZIF-8-derived Cu, N co-doped carbon as a bifunctional cathode catalyst for enhanced performance of microbial fuel cell - Bi-Lin Lai; Hui-Xu Wei; Zi-Nuo Luo; Tong Zheng; Yi-Hui Lin; Zhao-Qing Liu; Nan Li (Science of The Total Environment, 2023)

Within-crown plasticity of hydraulic properties influence branch dieback patterns of two woody plants under experimental drought conditions - Gui-Qing Xu; Tu-Qiang Chen; Shen-Si Liu; Jie Ma; Yan Li (Science of The Total Environment, 2023)

Charge instability of topological Fermi arcs in chiral crystal CoSi - Zhicheng Rao; Quanxin Hu; Shangjie Tian; Qing Qu; Congrun Chen; Shunye Gao; Zhenyu Yuan; Cenyao Tang; Wenhui Fan; Jierui Huang; Yaobo Huang; Li Wang; et al. (Science Bulletin, 2023)

Overexpression of Sly-miR164a in tomato decreases expression of NAC and delays pre- and postharvest ripening of fruit - Zhiqiang Wang; Qing Wang; Wenhui Duan; Lanhuan Meng; Jiangkuo Li; Hongmiao Song; Xiangbin Xu (Postharvest Biology and Technology, 2023)

Nitric oxide effects on postharvest and Alternaria-infected pear fruit - Suhui Zheng; Ruiqiang Xu; Jia Wei; Jia Tian; Qing He; Fulin Zhang; Jiang Li; Bin Wu; Junfeng Guan (Postharvest Biology and Technology, 2023)

Disruption of tetrahydrobiopterin (BH4) biosynthesis pathway affects cuticle pigmentation in Henosepilachna vigintioctopunctata - Long-Ji Ze; Ping Xu; Jian-Jian Wu; Lin Jin; Ahmad Ali Anjum; Guo-Qing Li (Journal of Insect Physiology, 2023)

The landscape of micron-scale particles including microplastics in human enclosed body fluids - Quanquan Guan; Jin Jiang; Yan Huang; Qing Wang; Zhaofeng Liu; Xuan Ma; Xiaona Yang; Yong Li; Shangqian Wang; Weiding Cui; Junwei Tang; Hua Wan; et al. (Journal of Hazardous Materials, 2023)

Learn then match: A fast coarse-to-fine depth image-based indoor localization framework for dark environments via deep learning and keypoint-based geometry alignment - Qing Li; Rui Cao; Jiasong Zhu; Hao Fu; Baoding Zhou; Xu Fang; Sen Jia; Shenman Zhang; Kanglin Liu; Qingquan Li (ISPRS Journal of Photogrammetry and Remote Sensing, 2023)

A novel approach to investigating 3D fracture connectivity in ultrahigh steep rock slopes - Yansong Zhang; Jianping Chen; Fujun Zhou; Wen Zhang; Jianhua Yan; Yuchao Li; Zhihai Li; Mingyu Zhao; Wanglai Xu; Yongqiang Liu; Qing Wang (International Journal of Rock Mechanics and Mining Sciences, 2023)

Thermal behavior, synergistic effect and thermodynamic parameter evaluations of biomass/plastics co–pyrolysis in a concentrating photothermal TGA - Abdulmajid Abdullahi Shagali; Song Hu; Hanjian Li; Huanying Chi; Haoran Qing; Jun Xu; Long Jiang; Yi Wang; Sheng Su; Jun Xiang (Fuel, 2023)

Ultrasonic-assisted stewing enhances the aroma intensity of chicken broth: A perspective of the aroma-binding behavior of fat - Jun Qi; Chuan-kang Jia; Wen-wen Zhang; Hui-min Yan; Qing-yuan Cai; Xiu-ning Yao; Kuo Xu; Ying Xu; Wen-ping Xu; Guo-yuan Xiong; Mei-qi Li (Food Chemistry, 2023)

Association between long-term ambient ozone exposure and attention-deficit/hyperactivity disorder symptoms among Chinese children - Peien Zhou; Wangjian Zhang; Yu-Jie Xu; Ru-Qing Liu; Zhengmin Qian; Stephen Edward McMillin; Elizabeth Bingheim; Li-Zi Lin; Xiao-Wen Zeng; Bo-Yi Yang; Li-Wen Hu; Wen Chen; et al. (Environmental Research, 2023)

Association between ambient carbon monoxide levels and hospitalization costs of patients with myocardial infarction: Potential effect modification by ABO blood group - Qing-Song Huang; Lai-Xin Zhou; Li-Li Yang; Yue-Xu Jiang; Hua Xiao; Da-Wei Li; Yu-Meng Zhou; Yue-Gu Hu; Na Li; Ya-Fei Li; Ai-Ling Ji; Peng Luo; et al. (Environmental Research, 2023)

Multifunctional binder capable of promoting the reaction dynamics of wide temperature operable lithium-sulfur battery - Chen Li; Qifang Sun; Qing Zhang; Chaoran Xu; Su Wang; Yue Ma; Xixi Shi; Hongzhou Zhang; Dawei Song; Lianqi Zhang (Chemical Engineering Journal, 2023)

Two silver energetic coordination polymers based on a new N-amino-contained ligand: Towards good detonation performance and excellent laser-initiating ability - Qing Lang; Xinyi Li; Jianxin Zhou; Yuangang Xu; Qiuhan Lin; Ming Lu (Chemical Engineering Journal, 2023)

Low concentrations of benzophenone-type UV-filters impair testis development in the amphibian Xenopus laevis - Hong-Mei Li; Ying-Chi Zhang; Yuan-Yuan Li; Qing-Qing Zhu; Jie Li; Hai-Ming Xu; Yi-Ming Xiong; Zhan-Fen Qin (Aquatic Toxicology, 2023)

Positional cloning identified HvTUBULIN8 as the candidate gene for round lateral spikelet (RLS) in barley (Hordeum vulgare L.) - Dandan Qin; Gang Liu; Rui Liu; Chunchao Wang; Fuchao Xu; Qing Xu; Yu Ling; Guoqing Dong; Yanchun Peng; Shuangtao Ge; Ganggang Guo; Jing Dong; et al. (Theoretical and Applied Genetics, 2023)
Key message Map-based cloning, subcellular localization, virus-induced-gene-silencing and transcriptomic analysis reveal HvTUB8 as a candidate gene with pleiotropic effects on barley spike and leaf development via ethylene and chlorophyll metabolism. Abstract Barley lateral spikelet morphology and grain shape play key roles in grain physical quality and yield. Several genes and QTLs for these traits have been cloned or fine mapped previously. Here, we report the phenotypic and genotypic analysis of a barley mutant with round lateral spikelet (rls) from cv. Edamai 934. rls had round lateral spikelet, short but round grain, shortened awn, thick glume and dark green leaves. Histocytologic and ultrastructural analysis revealed that the difference of grain shape of rls was caused by change of cell arrangement in glume, and the dark leaf color resulted from enlarged chloroplast. HvTUBULIN8 ( HvTUB8 ) was identified as the candidate gene for rls by combination of RNA-Seq, map-based-cloning, virus-induced-gene-silencing (VIGS) and protein subcellular location. A single G-A substitution at the third exon of HvTUB8 resulted in change of Cysteine 354 to tyrosine. Furthermore, the mutant isoform Hvtub8 could be detected in both nucleus and cytoplasm, whereas the wild-type protein was only in cytoplasm and granular organelles of wheat protoplasts. Being consistent with the rare phenotype, the “A” allele of HvTUB8 was only detected in rls , but not in a worldwide barley germplasm panel with 400 accessions. VIGS confirmed that HvTUB8 was essential to maintain spike integrity. RNA-Seq results suggested that HvTUB8 may control spike morphogenesis via ethylene homeostasis and signaling, and control leaf color through chlorophyll metabolism. Collectively, our results support HvTUB8 as a candidate gene for barley spike and leaf morphology and provide insight of a novel mechanism of it in barley development.

Genetic diversity in early maturity Chinese and European elite soybeans: A comparative analysis - Xindong Yao; Jiang-yuan Xu; Zhang-xiong Liu; Martin Pachner; Eva Maria Molin; Leopold Rittler; Volker Hahn; Willmar Leiser; Yong-zhe Gu; Yu-qing Lu; Li-juan Qiu; Johann Vollmann (Euphytica, 2023)
Soybean ( Glycine max [L.] Merr.) is a legume crop important for global food security due to supplying high-quality vegetable protein and oil. China is the origin and rich center of soybean genetic diversity represented by numerous landraces and other genetic resources. During the nineteenth and twentieth centuries, world-wide dissemination of plant introductions laid the foundation of modern soybean production. Due to selection for regional adaptation, present-day elite soybean cultivars do have a comparatively narrow genetic base. However, as genetic variation is the major component of future breeding progress, diversity of early maturity Chinese and European elite soybeans was comparatively analyzed using a high-throughput functional SNP array and an SSR marker set. Results revealed a clear differentiation between Chinese and European elite cultivars, and the level of genetic diversity was similar between the two populations. Both in Chinese and European cultivars, unique SSR alleles were found which indicates that selection for specific adaptation can preserve genetic variation. The European population was markedly structured by maturity groups which was less clear in the Chinese population. Structure analysis indicated that European cultivars are based on two major ancestral lines, whereas Chinese elite soybean cultivars trace back to more ancestral lines pointing to the rich natural soybean diversity of China. The results confirm that long-term selection under divergent environmental and agronomic conditions can produce specific diversity which could potentially be utilized for future enhancing both Chinese and European soybean breeding.

Cymbopogom Citratus Essential Oils: A Promising Source of Antifungals Against Panax Notoginseng-Associated Pathogenic Fungi - Jing Yang; Tian T. Li; Ying Y. Huo; Heng Y. Huang; Qing H. Meng; Fu R. Xu; Xian Dong (Current Microbiology, 2023)

Water-in-zircon: a discriminant between S- and I-type granitoid - Jing Mo; Xiao-Ping Xia; Peng-Fei Li; Christopher J. Spencer; Chun-Kit Lai; Jian Xu; Qing Yang; Ming-Dao Sun; Yang Yu; Luke Milan (Contributions to Mineralogy and Petrology, 2023)

Uncovering expression and functional analysis of newly discovered high-affinity K+ transporter family members from sugarcane - Hai-bin Luo; Cheng-mei Huang; Yuan-wen Wei; Hui-ming Zhu; Hui-qing Cao; Sheng-li Jiang; Zhi-nian Deng; Kai-chao Wu; Lin Xu (Journal of Plant Biochemistry and Biotechnology, 2022)

Inhibition of Microglial NLRP3 with MCC950 Attenuates Microglial Morphology and NLRP3/Caspase-1/IL-1β Signaling In Stress-induced Mice - Qing Liu; Man-Man Zhang; Min-Xia Guo; Qiu-Ping Zhang; Na-Zhi Li; Jie Cheng; Shi-Le Wang; Guang-Hui Xu; Cheng-Fu Li; Ji-Xiao Zhu; Li-Tao Yi (Journal of Neuroimmune Pharmacology, 2022)

STING/NF-κB/IL-6-Mediated Inflammation in Microglia Contributes to Spared Nerve Injury (SNI)-Induced Pain Initiation - Jia Sun; Ya-qun Zhou; Bing-yang Xu; Jia-yan Li; Long-qing Zhang; Dan-yang Li; Shuang Zhang; Jia-yi Wu; Shao-jie Gao; Da-wei Ye; Wei Mei (Journal of Neuroimmune Pharmacology, 2022)

46,XY disorders of sex development: the use of NGS for prevalent variants - Qi-Gen Xie; Peng Luo; Kai Xia; Zuo-Qing Li; Zhe Xu; Cheng Su; Chun-Hua Deng (Human Genetics, 2022)

Comparison of infections with respiratory syncytial virus between children and adults: a multicenter surveillance from 2015 to 2019 in Beijing, China - Ming Luo; Cheng Gong; Yan Zhang; Xue Wang; Yang Liu; Qing Luo; Maozhong Li; Aihua Li; Yiting Wang; Mei Dong; Wenbo Xu; Fang Huang (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

High-temperature exposure and risk of spontaneous abortion during early pregnancy: a case–control study in Nanjing, China - Shuangshuang Zhao; Jie Xu; Wen Li; Yingying Lu; Linxiang Huang; Haoyi Xu; Mingxia Shi; Yan Wang; Qiaoying Zhu; Qing Xu (Environmental Science and Pollution Research, 2022)

Will farmers follow their peers in adopting straw returning? Evidence from rural Sichuan Province, China - Yanjiao Li; Chen Qing; Shili Guo; Xin Deng; Jiahao Song; Dingde Xu (Environmental Science and Pollution Research, 2022)

Starvation shrinks the mussel foot secretory glands and impairs the byssal attachment - Yi Zheng; Yue-Ming Yang; Yue-Feng Xu; Yu-Qing Wang; Xue Shi; Gao-Hai Zheng; Yi-Feng Li (Frontiers in Marine Science, 2022)
Mussel is an economically and ecologically important species widely distributed throughout the world. The mussel adheres to the attachment substrate by secreting byssus external to the body. Various environmental and biological factors influence the process of byssus secretion, and the present study investigated the effect of starvation on byssal secretion in the hard-shelled mussel Mytilus coruscus . Histological changes in mussel foot secretory glands and gene expression of mussel foot proteins were also determined. The experimental setup consisted of starvation treatments for 7, 14 and 21 days, and the control groups. The results showed that the number of produced byssus was higher in the starvation group compared to the control (CTR) group, and the starvation group had a significantly higher of byssal shedding number from 6 days of starvation treatment onwards ( p < 0.05). The byssal thread diameter was significantly reduced in all starvation treatment groups ( p < 0.05). However, starvation treatment had no effect on the length of the byssal thread ( p > 0.05). After 21 days of starvation treatment, the byssal thread volume was significantly lower than that of the CTR group ( p < 0.05). A significant decrease in the breaking force of the byssal thread was observed after 14 and 21 days of starvation treatment ( p < 0.05), along with an upward shift in the breakpoints. Starvation treatment significantly reduced the percentage of foot secretory glands area to total tissue ( p < 0.05). The expression of the mussel foot protein genes ( Mcfp-1P and Mcfp-1T ) was significantly up-regulated at 7 days of starvation treatment ( p < 0.05). These findings reveal that starvation weakens byssal thread performance by influencing mussel foot secretory glands, which increases the dislodgment risks of suspended-cultured mussels.

Preparation of Pinocembrin-Loaded F127/MPEG-PDLLA Polymer Micelles and Anti-Osteoporotic Activity - Xia Cao; Qing He; Michael Adu-Frimpong; Xinyi Shen; Wanjing Rong; Xiaoxiao Li; Jian Zhang; Xiaoli Xia; Feng Shi; Hao Ji; Elmurat Toreniyazov; Qilong Wang; et al. (AAPS PharmSciTech, 2022)

The association between short-term ambient sulfur dioxide exposure and hospitalization costs of ischemic stroke: a hospital-based study in Chongqing, China - En-Jie Tang; Yu-Meng Zhou; Li-Li Yang; Nan Wang; Yue-Xu Jiang; Hua Xiao; Yue-Gu Hu; Da-Wei Li; Na Li; Qing-Song Huang; Ning Du; Ya-Fei Li; et al. (Environmental Science and Pollution Research, 2022)

Selective TAAR1 agonists induce conditioned taste aversion - Jianfeng Liu; Ruyan Wu; Bernard Johnson; Yanan Zhang; Qing Zhu; Jun-Xu Li (Psychopharmacology, 2022)

Screening for SH3TC2 variants in Charcot–Marie–Tooth disease in a cohort of Chinese patients - Bo Sun; Zheng-Qing He; Yan-Ran Li; Jiong-Ming Bai; Hao-Ran Wang; Hong-Fen Wang; Fang Cui; Fei Yang; Xu-Sheng Huang (Acta Neurologica Belgica, 2022)

Transcriptome Analysis of Greenfin Horse-Faced Filefish (Thamnaconus septentrionalis) Gills in Response to Amyloodinium ocellatum (AO) Infection - Li-Guo Yang; Yue Wang; Wen-Bin Xu; Bo Qin; Na Ying; Xue-Feng Song; Yan-Feng Yue; Xiao-Shan Wang; Bian-Bian Zhang; Yan-Qing Wu (Fishes, 2022)
The greenfin horse-faced filefish (Thamnaconus septentrionalis) is susceptible to recurrent Amyloodinium ocellatum (AO) infestation over the grow-out production cycle. This parasite breeds mainly on the gills, causing hypoxia in the fish body, and leading to many deaths. The host-parasite response drives a complex immune reaction, which is poorly understood. To generate a model for host-parasite interaction and the pathogenesis of AO in greenfin horse-faced filefish, an RNA-seq approach, differential gene expression, GO, and KEGG analyses were employed. Overall, 624 new genes and 2076 differentially expressed genes (DEGs) were detected, including 942 upregulated and 1134 downregulated genes in the gills. Compared with the control group, the expression of leptin a, GTPase IMAP family member 4, and NLR family CARD domain-containing protein 3 was significantly higher in the AO-infected group. Conversely, cell wall integrity and stress response component 1-like, and hepcidin-like were significantly downregulated in the gills of AO-infected fish. GO and KEGG enrichment analysis indicated that DEGs were significantly enriched in signaling pathways associated with viral protein interaction with cytokine and cytokine receptor and cytokine–cytokine receptor interaction. Collectively, this transcriptomic study provides novel molecular insights into the pathology caused by AO infestation and alternative theories for future research implementing strategies to control and manage AO.

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Association between ambient temperature and ambulance dispatch: a systematic review and meta-analysis - Er Xu; Yanni Li; Tingting Li; Qing Li (Environmental Science and Pollution Research, 2022)

Negative air ion exposure ameliorates depression-like behaviors induced by chronic mild stress in mice - Yun-Qing Hu; Ting-Ting Niu; Jian-ming Xu; Li Peng; Qing-Hua Sun; Ying Huang; Ji Zhou; Yu-Qiang Ding (Environmental Science and Pollution Research, 2022)
The presence of negative air ions (NAI) is suggested to be a beneficial factor in improving psychological status and used in treating depression as an alternative approach. However, more biological evidence from animal models is needed to ensure the effects of NAI on the mood regulation, through which can facilitate identification of possible underlying mechanisms. In this study, the chronic mild stress (CMS) protocol was used to induce depressive-like behaviors in mice, and the effects of NAI exposure on CMS-induced depression-like behaviors were examined. Thirty-day NAI exposure prevented the CMS-induced depression-like behaviors as shown by the restoration of sucrose preference and reduced immobility time in the tail suspension test. In addition, the elevation of serous corticosterone was present in CMS-treated mice but not existed in those with the NAI exposure. Furthermore, we observed altered ratios of some cytokines secreted by type 1 T helper (Th1) cells and Th2 cells in CMS-treated mice, but it could be restored after NAI exposure. In conclusion, NAI intervention is able to ameliorate CMS-induced depression-like behaviors in mice, and this effect is associated with the alteration of corticosterone and functional rebalance between Th1 and Th2 cells.

Ensemble forecast of tropical cyclone tracks based on deep neural networks - Chong Wang; Qing Xu; Yongcun Cheng; Yi Pan; Hong Li (Frontiers of Earth Science, 2022)

Starch accumulation dynamics and transcriptome analysis of Chlorella sorokiniana during transition of sulfur nutritional status - Haiqing Xu; Jinzhi Yang; Xu Wang; Qing Peng; Yanxia Han; Xudong Liu; Kexin Liu; Shijuan Dou; Liyun Li; Guozhen Liu; Ming Yang (Frontiers in Marine Science, 2022)
Microalgae can effectively accumulate starch by using nutritional limitation methods in the context of bioalcohol fuel production. However, relatively few studies have focused on starch accumulation in microalgae and its molecular basis, especially under sulfur limitation conditions. In this study, the starch accumulation dynamics and physiological responses of Chlorella sorokiniana under sulfur starvation (SS) and sulfur replenishment (SR) conditions were investigated, and the genes involved in the transcriptional regulation were explored using RNA-seq. The starch content in C. sorokiniana cells significantly increased from 1.6% to 55.0% of dry weight within 24 h under SS conditions, and then, it decreased to 3.4% within 12 h after transition to SR conditions. However, cell growth was inhibited, and pigment content decreased under SS conditions. Using RNA-seq analysis, a total of 9720 differentially expressed genes (DEGs) induced by sulfur status were obtained. These genes were narrowed down to 454 starvation and replenishment cross-validated (SRV)-DEGs, among which 283 SRV-DEGs were significantly up-regulated and 171 SRV-DEGs were down-regulated under SS conditions, and returned to their previous state under SR conditions. The SRV-DEGs enriched in the sulfate metabolism pathway were all up-regulated under SS conditions after 6 h to speed up the sulfur metabolic cycle, and the transcriptional abundance of a sulfate transporter (SULTR4), cysteine synthase[O-acetylserine(thiol)-lyase] (OASTL), serine acetyltransferase (SAT), and methanethiol oxidase (SELENBP1) increased 8.6-fold, 12.6-fold, 8.7-fold, and 12.4-fold, respectively. Protein synthesis was correspondingly inhibited, which resulted in the reallocation of carbon and elevated the starch synthesis pathway, in which the expressions of glycogen branching enzyme (GBE) and starch synthase (SS) were up-regulated 12.0- and 3.0-fold, respectively. The fatty acid desaturase (FAD) and phosphatidic acid phosphatase (PAP) in the lipid synthesis pathway were strongly up-regulated 8.8- and 16.2-fold, respectively, indicating the competitive synthesis of lipids. The down-regulation of SRV-DEGs associated with carbon fixation, such as those in the Calvin cycle, possibly affected cell growth. The time-resolved transcriptional analysis identified the SRV-DEGs, revealing the underlying starch accumulation mechanism, as well as the relationship with cell growth and lipid synthesis.

Preparation and Biocompatibility Study of Contrast-Enhanced Hernia Mesh Material - Xuzhong Ding; Jiachen Zhu; Anning Liu; Qiyang Guo; Qing Cao; Yu Xu; Ye Hua; Yumin Yang; Peng Li (Tissue Engineering and Regenerative Medicine, 2022)

MSC Promotes the Secretion of Exosomal miR-34a-5p and Improve Intestinal Barrier Function Through METTL3-Mediated Pre-miR-34A m6A Modification - Yi-Jun Li; Qing-Wen Xu; Cong-Hui Xu; Wei-Ming Li (Molecular Neurobiology, 2022)

Comparison of Behavior, Histology and ImpL2 Gene Expression of Octopus sinensis Under Starvation and Senescence Conditions - Li Bian; Fenghui Li; Qing Chang; Changlin Liu; Jie Tan; Shengnong Zhang; Xuemei Li; Meishuai Li; Yikang Sun; Rongjing Xu; Siqing Chen (Frontiers in Marine Science, 2022)
Offshore cephalopods usually experience a short and extreme senescence process at the end of their lives. Unique behaviors such as brooding and fasting occur during this period. The cause of senescent cephalopod death is still unknown. Excessive energy consumption under prolonged starvation is one possible reason for death. A comparison analysis between normal starvation and senescence may provide valuable information to deepen our understanding of the senescence process of cephalopods. In this study, a comparison of behavior, histology and expression of a candidate senescence-specific gene (Imaginal morphogenesis protein-Late 2, ImpL2) of female Octopus sinensis under normal starvation and senescence was conducted. The females in the starvation group had similar behaviors, histology and ImpL2 expression level to the control group. The females in the senescence group exhibited typical behaviors and symptoms of senescent octopus, including fasting and unhealed lesions on the skin. Moreover, swimming and grasping ability was weakened in senescent individuals. The muscle tissue in the mantle and arm of senescent females showed a histolytic appearance. The secretory cells and their microvilli in the digestive gland gradually degraded and disappeared during senescence. The expression level of ImpL2 gene significantly changes in multiple organs of senescent females. The results showed that O. sinensis underwent different physiological and molecular processes during starvation and senescence. Starvation alone could not lead to senescent symptoms in the octopus. Tissue degeneration in the mantle, arm and digestive gland would increase the death risk of the octopus.

Temporal Dynamics in Energy Fluxes and Trophic Structure of a Portunus trituberculatus Polyculture Ecosystem During Different Culture Periods - Jie Feng; Xiang-Li Tian; Shuang-Lin Dong; Rui-Peng He; Kai Zhang; Dong-Xu Zhang; Qing-Qi Zhang (Frontiers in Marine Science, 2022)
Swimming crab ( Portunus trituberculatus ) are an important aquaculture species in eastern coastal areas of China. To improve the understanding of P. trituberculatus culture ecosystem functioning, the dynamics of energy flow and trophic structure of a P. trituberculatus polyculture system (co-culture with white shrimp Litopenaeus vannamei and short-necked clam Ruditapes philippinarum ) were investigated in this study. Three Ecopath models representing the early, middle, and late culture periods of a P. trituberculatus polyculture ecosystem, respectively, were constructed to compare ecosystem traits at different culture periods. The results demonstrated that detritus was the main energy source in this polyculture ecosystem, and most of the total system throughput occurred at trophic levels I and II. Artificial food input and consumption by the culture organisms increased from early to middle and late periods, which produced marked impacts on biomass structure and primary production. R. philippinarum was considered to have a dominant influence on phytoplankton community dynamics which changed from nano- to pico-phytoplankton predominance, from the middle to the late period. Considering the low utilization efficiency of pico-phytoplankton production, large amounts of detritus accumulated in the sediment in the late period, which may constitute a potential risk for the ecosystem. Ecological network analyses indicated that the total energy flow and level of system organization increased from the early to the middle and late periods, whereas food web complexity and system resilience decreased from early to middle and late periods, which may indicate a trend of decreasing ecosystem stability. The system may be further optimized by increased stocking density of R. philippinarum and by introducing macro-algae at a suitable biomass to increase ecosystem stability, energy utilization efficiency, and aquaculture production.

Whole-transcriptome sequencing identifies key mRNAs, miRNAs, lncRNAs, and circRNAs associated with unexplained recurrent pregnancy loss - Yan Wang; Qing Cheng; Zhengyi Xia; Ran Zhou; Yiming Li; Lulu Meng; Qing Xu; Jianxin Tan; Zhengfeng Xu (Cell and Tissue Research, 2022)

Anti-inflammatory and antioxidant activities of chemical constituents from the flower buds of Buddleja officinalis - Fei-Bing Huang; Na Liang; Nusrat Hussain; Xu-Dong Zhou; Muhammad Ismail; Qing-Ling Xie; Huang-He Yu; Yu-Qing Jian; Cai-Yun Peng; Bin Li; Bin Liu; Sheng-Huang Chen; et al. (Natural Product Research, 2022)

Research on Ecological Security of Shengjin Lake Wetland (Anhui Province of China) Based on TM Images - Zhili Xu; Bin Dong; Xiang Gao; Ping Wang; Qing Wang; Sheng Li; Haifeng Xu; Yaru Liu; Tong Wang; Chunqiu Ren (Journal of the Indian Society of Remote Sensing, 2022)

Stability evaluation for steep bank slope with microseismic monitoring in Three Gorges Reservoir area - Qing-ming Xie; Kui Long; Zi-mu Li; Li-chuan Chen; Hong Liu; Hong Xu; Fei He; Dan Liang; Xue-kun Xiang; Qiang Ma (Journal of Mountain Science, 2022)

Identification of Key Pathways and Genes in SARS-CoV-2 Infecting Human Intestines by Bioinformatics Analysis - Ji-Chun Chen; Tian-Ao Xie; Zhen-Zong Lin; Yi-Qing Li; Yu-Fei Xie; Zhong-Wei Li; Xu-Guang Guo (Biochemical Genetics, 2022)
COVID-19 is a serious infectious disease that has recently swept the world, and research on its causative virus, SARS-CoV-2, remains insufficient. Therefore, this study uses bioinformatics analysis techniques to explore the human digestive tract diseases that may be caused by SARS-CoV-2 infection. The gene expression profile data set, numbered GSE149312, is from the Gene Expression Omnibus (GEO) database and is divided into a 24-h group and a 60-h group. R software is used to analyze and screen out differentially expressed genes (DEGs) and then gene ontology (GO) term and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses are performed. In KEGG, the pathway of non-alcoholic fatty liver disease exists in both the 24-h group and 60-h group. STRING is used to establish a protein–protein interaction (PPI) network, and Cytoscape is then used to visualize the PPI and define the top 12 genes of the node as the hub genes. Through verification, nine statistically significant hub genes are identified: AKT1, TIMP1, NOTCH, CCNA2, RRM2, TTK, BUB1B, KIF20A, and PLK1. In conclusion, the results of this study can provide a certain direction and basis for follow-up studies of SARS-CoV-2 infection of the human digestive tract and provide new insights for the prevention and treatment of diseases caused by SARS-CoV-2.

Medicinal herbs and phytochemicals to combat pathogens in aquaculture - Mengmeng Li; Dongdong Wei; Shuaishuai Huang; Lin Huang; Fengqiao Xu; Qing Yu; Mingzhu Liu; Pengfei Li (Aquaculture International, 2022)

Comparative Analysis of Pseudo-nitzschia Chloroplast Genomes Revealed Extensive Inverted Region Variation and Pseudo-nitzschia Speciation - Ziyan He; Yang Chen; Yichao Wang; Kuiyan Liu; Qing Xu; Yang Li; Nansheng Chen (Frontiers in Marine Science, 2022)
Pseudo-nitzschia is a species-rich genus where many species can induce harmful algae blooms (HABs) associated with the toxin domoic acid (DA) production. Despite the importance of Pseudo-nitzschia species to coastal environments, their genomic information is rather limited, hindering research on biodiversity and evolutionary analysis. In this study, we report full-length chloroplast genomes (cpDNAs) of nine Pseudo‐nitzschia , among which cpDNAs of eight Pseudo-nitzschia species were reported for the first time. The sizes of these Pseudo-nitzschia cpDNAs, which showed typical quadripartite structures, varied substantially, ranging from 116,546 bp to 158,840 bp in size. Comparative analysis revealed the loss of photosynthesis-related gene psaE in cpDNAs of all Pseudo-nitzschia species except that of P. americana , and the selective loss of rpl36 in P. hainanensis . Phylogenetic analysis showed that all Pseudo-nitzschia strains were grouped into two clades, with clade 1 containing cpDNAs of P. multiseries , P. pungens , P. multistriata , and P. americana , and clade 2 containing cpDNAs of P. hainanensis , P. cuspidata , Pseudo-nitzschia sp. CNS00097, P. delicatissima , and P. micropora . The small size of the P. americana cpDNA was primarily due to its shortened inverted repeat (IR) regions. While psaA and psaB were found in the IR regions of cpDNAs of other eight species, these two genes were found outside of the IR regions of P. americana cpDNA. In contrast, P. hainanensis had the largest size because of expansion of IR regions with each IR region containing 15 protein-coding genes (PCGs). Eleven genetic regions of these Pseudo-nitzschia cpDNAs exhibited high nucleotide diversity (Pi) values, suggesting that these regions may be used as molecular markers for distinguishing different Pseudo-nitzschia species with high resolution and high specificity. Phylogenetic analysis of the divergence of nine Pseudo-nitzschia species indicated that these species appeared at approximately 41 Mya. This study provides critical cpDNA resources for future research on the biodiversity and speciation of Pseudo-nitzschia species.

A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam - Yi-Fan Yu; Yue-Qian Li; Ru-Yue Wang; Xu Liu; Wen-Bo Cui; Xiao-Han Chen; Cheng-Mu Zhao; Feng-Ming Qi; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

Mutation of Beclin1 acetylation site at K414 alleviates high glucose-induced podocyte impairment in the early stage of diabetic nephropathy by inhibiting hyperactivated autophagy - Jun Xu; Yujie Deng; Yingying Ke; Yunxia Zhu; Ping Wang; Qing Yu; Chengqian Li; Bimin Shi (Molecular Biology Reports, 2022)

Hyperlipidemia patients carrying LDLR splicing mutation c.1187-2A>G respond favorably to rosuvastatin and PCSK9 inhibitor evolocumab - Xiaoyu Zhang; Qianqian Liu; Hongfu Zhang; Chengcheng Tan; Qiangfeng Zhu; Saiyong Chen; Yinglong Du; Haitao Yang; Qingli Li; Chengqi Xu; Chun Wu; Qing K. Wang (Molecular Genetics and Genomics, 2022)

Responses of photosynthesis, antioxidant enzymes, and related gene expression to nicosulfuron stress in sweet maize (Zea mays L.) - Zhen-Xing Wu; Ning-Wei Xu; Min Yang; Xiang-Ling Li; Jin-Ling Han; Xiao-Hu Lin; Qing Yang; Gui-Hua Lv; Jian Wang (Environmental Science and Pollution Research, 2022)

Reproductive Dynamics of the Large Yellow Croaker Larimichthys crocea (Sciaenidae), A Commercially Important Fishery Species in China - Li-ting Yan; Yan Jiang; Qing Xu; Guang-mao Ding; Xin-yi Chen; Min Liu (Frontiers in Marine Science, 2022)
The large yellow croaker Larimichthys crocea (Richardson, 1846) (Sciaenidae) is distributed in southern Yellow Sea, East China Sea, and northern South China Sea of China and is a commercially important nearshore fishery species. L. crocea was listed on the IUCN Red List as “Critically Endangered” in 2020 mainly due to the over-exploration of its spawning and over-wintering aggregations in the 1950s–1980s throughout its distribution region. However, detailed studies on reproductive dynamics of L. crocea were limited in the past three decades. In this study, the reproductive dynamics of L. crocea was examined in the traditional Guanjingyang (GJY) spawning ground, one of the 15 well-known ones in its distribution region. Samples were collected using set nets from April 2019 to November 2021 to ensure at least 20 samples for all 12 months. A total of 1,006 individuals were caught, ranging from 46 to 391 mm standard length (SL) and 1.45 to 1,110.05 g body weight (BW). A growth dimorphism was found between sexes with females heavier than males when body sizes exceeded 61 mm SL (non-parametric ANCOVA, p < 0.01). Gonad histology of all 1,006 individuals revealed, for the first time, that L. crocea was able to spawn almost year-round for both females and males. Two spawning peaks, spring and autumn, were identified in March and May and in November for females and in April to June and in October to November for males. The minimum sizes at sexual maturity were 160 mm SL for females and 112 mm SL for male. The sizes at 50% sexual maturity were 187.2 mm SL for females and 150.2 mm SL for males. Results showed that the minimum SL for female maturity decreased about 20% in the past six decades. The spawning peaks were 2 months earlier in spring and 1 month extension in autumn in GJY. Clearly, the national fishing moratorium regulation in May to August, an important fishery management measure in China, can only protect the spring spawning peak partly. Further evaluation on the influence of climate change on reproductive strategies and stock recruitment of L. crocea is highly recommended.

Dynamics of nitrogen and phosphorus profile and its driving forces in a subtropical deep reservoir - Cunli Li; Ping Zhang; Guangwei Zhu; Chao Chen; Yucheng Wang; Mengyuan Zhu; Hai Xu; Cuiling Jiang; Wei Zou; Pengcheng Shi; Qing Zheng (Environmental Science and Pollution Research, 2022)

Insights into sorption and leaching behavior of sulfadiazine in soil as affected by humic acid - Qing Lin; Boliang Li; Xiaowen Liu; Budi Zhang; Shaohui Xu (Journal of Soils and Sediments, 2022)

Shewanella jiangmenensis sp. nov., isolated from aquaculture water - Yingli Song; Anzhang Li; Shuaishuai Xu; Mingxia Zhang; Qing Yao; Lian Ma; Honghui Zhu (Archives of Microbiology, 2022)

Can artificial light promote submerged macrophyte growth in summer? - Chao Xu; Hai-Jun Wang; Yan Li; Chi Xu; Qing Yu; Miao Liu; Miao Zhang; Hong-Zhu Wang; David P. Hamilton; Erik Jeppesen (Aquatic Ecology, 2022)

Delayed body development with reduced triglycerides levels in leptin transgenic pigs - Yubo Qing; Muhammad Ameen Jamal; Dejia Shi; Sumei Zhao; Kaixiang Xu; Deling Jiao; Heng Zhao; Honghui Li; Baoyu Jia; Haizhen Wang; Hong-Ye Zhao; Hong-Jiang Wei (Transgenic Research, 2022)

Oxidation of organoarsenicals and antimonite by a novel flavin monooxygenase widely present in soil bacteria - Jun Zhang; Jian Chen; Yi‐Fei Wu; Zi‐Ping Wang; Ji‐Guo Qiu; Xiao‐Long Li; Feng Cai; Ke‐Qing Xiao; Xiao‐Xu Sun; Barry P. Rosen; Fang‐Jie Zhao (Environmental Microbiology, 2022)
Summary Arsenic can be biomethylated to form a variety of organic arsenicals differing in toxicity and environmental mobility. Trivalent methylarsenite (MAs(III)) produced in the methylation process is more toxic than inorganic arsenite (As(III)). MAs(III) also serves as a primitive antibiotic and, consequently, some environmental microorganisms have evolved mechanisms to detoxify MAs(III). However, the mechanisms of MAs(III) detoxification are not well understood. In this study, we identified an arsenic resistance ( ars ) operon consisting of three genes, arsRVK , that contribute to MAs(III) resistance in Ensifer adhaerens ST2. ArsV is annotated as an NADPH‐dependent flavin monooxygenase with unknown function. Expression of arsV in the arsenic hypersensitive Escherichia coli strain AW3110 Δars conferred resistance to MAs(III) and the ability to oxidize MAs(III) to MAs(V). In the presence of NADPH and either FAD or FMN, purified ArsV protein was able to oxidize both MAs(III) to MAs(V) and Sb(III) to Sb(V). Genes with arsV ‐like sequences are widely present in soils and environmental bacteria. Metagenomic analysis of five paddy soils showed the abundance of arsV ‐like sequences of 0.12–0.25 ppm. These results demonstrate that ArsV is a novel enzyme for the detoxification of MAs(III) and Sb(III) and the genes encoding ArsV are widely present in soil bacteria.

Investigation of the risk of valproic acid–induced tremor: clinical, neuroimaging, and genetic factors - Lili Lan; Xu Zhao; Si Jian; Cun Li; Man Wang; Qing Zhou; Shanshan Huang; Suiqiang Zhu; Huicong Kang; Heidi E. Kirsch (Psychopharmacology, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

Overexpression of the PLK4 Gene as a Novel Strategy for the Treatment of Autosomal Recessive Microcephaly by Improving Centrosomal Dysfunction - Ya-Song Xu; Zhi-Ying Su; Li Sun; Xiao-Mei Yang; Shi-Yu Sun; Xiao-Fei Ji; Yi-Zhen Ji; Su-Qing Zhang; Jie Tian; Qi-Chang Wu (Journal of Molecular Neuroscience, 2021)

Correction to: lncRNA MEG3, Acting as a ceRNA, Modulates RPE Differentiation Through the miR-7-5p/Pax6 Axis - Hong-Jing Sun; Fang-Fang Zhang; Qing Xiao; Jia Xu; Li-Jin Zhu (Biochemical Genetics, 2021)

lncRNA MEG3, Acting as a ceRNA, Modulates RPE Differentiation Through the miR-7-5p/Pax6 Axis - Hong-Jing Sun; Fang-Fang Zhang; Qing Xiao; Jia Xu; Li-Jin Zhu (Biochemical Genetics, 2021)

Controlling pathogenic risks of water treatment biotechnologies at the source by genetic editing means - Jie Wu; Dong‐Feng Liu; Hui‐Hui Li; Di Min; Jia‐Qi Liu; Peng Xu; Wen‐Wei Li; Han‐Qing Yu; Yong‐Guan Zhu (Environmental Microbiology, 2021)
Summary Antimicrobial‐resistant pathogens in the environment and wastewater treatment systems, many of which are also important pollutant degraders and are difficult to control by traditional disinfection approaches, have become an unprecedented treat to ecological security and human health. Here, we propose the adoption of genetic editing techniques as a highly targeted, efficient and simple tool to control the risks of environmental pathogens at the source. An ‘all‐in‐one’ plasmid system was constructed in Aeromonas hydrophila to accurately identify and selectively inactivate multiple key virulence factor genes and antibiotic resistance genes via base editing, enabling significantly suppressed bacterial virulence and resistance without impairing their normal phenotype and pollutant‐degradation functions. Its safe application for bioaugmented treatment of synthetic textile wastewater was also demonstrated. This genetic‐editing technique may offer a promising solution to control the health risks of environmental microorganisms via targeted gene inactivation, thereby facilitating safer application of water treatment biotechnologies.

MamZ protein plays an essential role in magnetosome maturation process of Magnetospirillum gryphiswaldense MSR-1 - Sha Wu; Qing Wang; Xu Wang; Ruixue Guo; Tongwei Zhang; Yongxin Pan; Feng Li; Ying Li (Journal of Oceanology and Limnology, 2021)

Geochemistry of the Lower Cretaceous limestones in the Eastern Tethys Gyabula Formation (Himalaya, southern Tibet): implications for the depositional environment and tectonic setting - Qing Li; Feng Ding; Micha Ruhl; Yongdong Wang; Ying Li; Lei Yang; Kunzhi Xu; Xiangang Xie (Arabian Journal of Geosciences, 2021)

Effects of Dietary Protein and Lipid Levels on Growth Performance, Muscle Composition, Immunity Index and Biochemical Index of the Greenfin Horse-Faced Filefish (Thamnaconus septentrionalis) Juvenile - Zhengxin Xu; Pengfei Zhang; Qing Chang; Siqing Chen; Li Bian; Zhida Wang (Journal of Ocean University of China, 2021)

A new indole alkaloid with HUVEC proliferation activities from Nauclea officinalis - Shi-Ying Mai; Yong-Hui Li; Xu-Guang Zhang; Yi-Ran Wang; Jun-Qing Zhang; An Jia (Natural Product Research, 2021)

MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean - Xiaolong Fang; Xiaoyuan Sun; Xiangdong Yang; Qing Li; Chunjing Lin; Jie Xu; Wenjun Gong; Yifan Wang; Lu Liu; Limei Zhao; Baohui Liu; Jun Qin; et al. (Science China Life Sciences, 2021)

Clinical characteristics and serotype distribution of invasive pneumococcal disease in pediatric patients from Beijing, China - Yan Xu; Qing Wang; Kaihu Yao; Fang Dong; Wenqi Song; Gang Liu; Baoping Xu; Wei Shi; Yue Li; Kechun Li; Yingchao Liu; Suyun Qian (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Recombinant L-HN Fusion Antigen Derived from the L and HN Domains of Botulinum Neurotoxin B Stimulates a Protective Antibody Response Against Active Neurotoxin - Zhen Li; Jian-Sheng Lu; Shan Liu; Rong Wang; Qing Xu; Yun-Zhou Yu; Zhi-Xin Yang (Neurotoxicity Research, 2021)

The Protective A673T Mutation of Amyloid Precursor Protein (APP) in Alzheimer’s Disease - Qing Xia; XinYu Yang; JiaBin Shi; ZiJie Liu; YaHui Peng; WenJing Wang; BoWen Li; Yu Zhao; JiaYing Xiao; Lei Huang; DaYong Wang; Xu Gao (Molecular Neurobiology, 2021)

Effects of drought and heat on the productivity and photosynthetic characteristics of alpine meadow plants on the Qinghai-Tibetan Plateau - Li Ma; Zhong-hua Zhang; Bu-qing Yao; Zhen Ma; Xiao-tao Huang; Bing-rong Zhou; Man-hou Xu; Jing Guo; Hua-kun Zhou (Journal of Mountain Science, 2021)

Comparison and Calibration of Elemental Measurements in Sediments Using X-Ray Fluorescence Core Scanning with ICP Methods: A Case Study of the South China Sea Deep Basin - Fangjian Xu; Bangqi Hu; Chen Wang; Jingtao Zhao; Feifei Wang; Xue Ding; Qing Li; Jianwei Guo (Journal of Ocean University of China, 2021)

Trade-offs/Synergies in Land-use Function Changes in Central China from 2000 to 2015 - Qing Li; Yong Zhou; Tao Xu; Li Wang; Qian Zuo; Jingyi Liu; Xueping Su; Nan He; Zhengxiang Wu (Chinese Geographical Science, 2021)

Short-term waterlogging-induced autophagy in root cells of wheat can inhibit programmed cell death - Li-Lang Zhou; Kai-Yue Gao; Li-Sha Cheng; Yue-Li Wang; Yi-Keng Cheng; Qiu-Tao Xu; Xiang-Yi Deng; Ji-Wei Li; Fang-Zhu Mei; Zhu-Qing Zhou (Protoplasma, 2021)

Calcineurin inhibitor–associated new-onset diabetes mellitus in chronic kidney disease treatment: a 4-year single-center cross-sectional study in China - Pan Kun-ming; Chen Can; Xu Qing; Wu Wei; Lv Qian-zhou; Li Xiao-yu (European Journal of Clinical Pharmacology, 2021)

Neurovascular Units and Neural-Glia Networks in Intracerebral Hemorrhage: from Mechanisms to Translation - Qing Sun; Xiang Xu; Tianyi Wang; Zhongmou Xu; Xiaocheng Lu; Xiang Li; Gang Chen (Translational Stroke Research, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Galectin-9 Promotes Neuronal Restoration via Binding TLR-4 in a Rat Intracerebral Hemorrhage Model - Tianyu Liang; Cheng Ma; Tianyi Wang; Ruming Deng; Jiasheng Ding; Wenjie Wang; Zhongmou Xu; Xiang Li; Haiying Li; Qing Sun; Haitao Shen; Zhong Wang; et al. (NeuroMolecular Medicine, 2021)

MiR-146a Negatively Regulates Aspergillus fumigatus-Induced TNF-α and IL-6 Secretion in THP-1 Macrophages - Jianbo Tong; Zhimin Duan; Rong Zeng; Leilei Du; Song Xu; Liwei Wang; Yuzhen Liu; Qing Chen; Xu Chen; Min Li (Mycopathologia, 2021)

Sesquiterpenoids from Pilea cavaleriei - Yong Zhou; Ling-Yu Li; Xu Yin; Qing-Ying Zhang; Hong Liang; Peng-Fei Tu (Natural Product Research, 2021)

On the ~ 7 year periodic signal in length of day from a frequency domain stepwise regression method - Can-Can Hsu; Peng-Shuo Duan; Xue-Qing Xu; Yong-Hong Zhou; Cheng-Li Huang (Journal of Geodesy, 2021)
The intradecadal variations in length-of-day (LOD) and their time-varying characteristics still need to be further studied. Given that the corresponding signal periods on the intradecadal scales are quite close to each other and the span of currently observed ΔLOD data (i.e., 1962–2019, only 57 years) is not long enough, accurate detection of these signals depends on using effective mathematical method. On the basis of the traditional harmonic retrieval model, this work proposes a frequency domain stepwise regression method, which can well identify the periodic components with close periods and recognize the weaker signals to estimate the relevant harmonic parameters (i.e., amplitude, frequency and phase). Furthermore, we apply this method to detection of the actual LOD intradecadal variations, the result of which shows that there are three components (i.e., the ~ 5.9 years, ~ 8.3 years and ~ 7.3 years) existing in LOD intradecadal variations. Here, we firstly give the time-domain harmonic expression of the ~ 7.3 years signal, i.e., $$y\left(t\right)=Acos\left(\frac{2π }{T}\left(t-1962+ψ \right)\right)$$ y t = A cos 2 π T t - 1962 + ψ , where the period $$T=7.33$$ T = 7.33 years, amplitude $$A=0.0413(± 0.0099)$$ A = 0.0413 ( ± 0.0099 ) ms, phase $$ψ =-1.58(± 0.30)$$ ψ = - 1.58 ( ± 0.30 ) years. The mechanism of this ~ 7.3 years signal needs to be further studied.

The optimal number of embryo cells for effective pregnancy and decrease of multiple pregnancy rate in frozen-thawed embryo transfer - Xu-Li Zhu; Zhi-Ming Zhao; Yuan-Jie Du; Liang Zhou; Yue Wang; Qing-Yun Sun; Gui-Min Hao; Bu-Lang Gao (Human Cell, 2021)

A novel Schiff base cobalt(III) complex induces a synergistic effect on cervical cancer cells by arresting early apoptosis stage - Wen-Hui Liao; Xue-Qing Song; Yan-Jie Kong; Rui-Dan Bao; Fang-Fang Li; Jie Zhou; Qi-Hua Zhao; Jing-Yuan Xu; Ni Xie; Ming-Jin Xie (BioMetals, 2021)

Complex microbial communities inhabiting natural Cordyceps militaris and the habitat soil and their predicted functions - Xiao-Mei Zhang; De-Xiang Tang; Qing-Qing Li; Yuan-Bing Wang; Zhi-Hong Xu; Wen-Jun Li; Hong Yu (Antonie van Leeuwenhoek, 2021)

Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China - Qing-Hai Wang; Xiang-Ying Li; Ting-Ting Xu; Meng-Ai Zhang; Yu-Hui Yang; Pei-Bo Feng; Su-Su Fan; Zhen-Yu Liu (Journal of General Plant Pathology, 2021)

Cloning and functional characterization of auxin receptor TIR1 in Gossypium hirsutum - Yu Wu; Hainan Ming; Jing Xu; Jie Bing; Qing Chen; Qing Wang; Hongjie Li; Genfa Zhang (Acta Physiologiae Plantarum, 2021)

Alkaloids and phenylpropanoid from Rhizomes of Arundo donax L - Qing-Ru Liu; Juan Li; Xiao-Fang Zhao; Bo Xu; Xing-Hua Xiao; Jie Ren; Shun-Xiang Li (Natural Product Research, 2021)

TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial–mesenchymal transition - Zhi-Han Li; Lei Lei; Liang-Ru Fei; Wen-Jing Huang; Yi-Wen Zheng; Mai-Qing Yang; Zhao Wang; Chen-Chen Liu; Hong-Tao Xu (Journal of Molecular Histology, 2021)

Construction and characterization of UAA-controlled recombinant Zika virus by genetic code expansion - Rong-Rong Zhang; Qing Ye; Xiao-Feng Li; Yong-Qiang Deng; Yan-Peng Xu; Xing-Yao Huang; Qing Xia; Cheng-Feng Qin (Science China Life Sciences, 2021)

FED: a web tool for foreign element detection of genome-edited organism - Qing Liu; Xiaozhen Jiao; Xiangbing Meng; Chun Wang; Cao Xu; Zhixi Tian; Chuanxiao Xie; Genying Li; Jiayang Li; Hong Yu; Kejian Wang (Science China Life Sciences, 2021)

7,8-Dihydroxyflavone Alleviates Anxiety-Like Behavior Induced by Chronic Alcohol Exposure in Mice Involving Tropomyosin-Related Kinase B in the Amygdala - Na Wang; Xing Liu; Xin-Tong Li; Xin-Xin Li; Wei Ma; Yan-Min Xu; Yong Liu; Qing Gao; Tao Yang; Hongxuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2021)

Safety of hydroxychloroquine in COVID-19 and other diseases: a systematic review and meta-analysis of 53 randomized trials - Can Chen; Kunming Pan; Bingjie Wu; Xiaoye Li; Zhangzhang Chen; Qing Xu; Xiaoyu Li; Qianzhou Lv (European Journal of Clinical Pharmacology, 2021)

Long-term impact of accidental pollution on the distribution and risks of metals and metalloids in the sediment of the Longjiang River, China - Qian-Li Ma; Ling-Ai Yao; Qing-Wei Guo; Guang-Jie Zhou; Rong-Chang Liang; Qiao-Li Fang; Zhen-Cheng Xu; Xue-Min Zhao (Environmental Science and Pollution Research, 2021)

Distance decay of place attachment and perceived authenticity of mountain tourism destinations in China - Xiao Xiao; Jie Zhang; Jun-yu Lu; Li Li; Yan-qing Xu; Hong-lei Zhang; Geoffrey K. Riungu (Journal of Mountain Science, 2021)

Tuberculosis relapse is more common than reinfection in Beijing, China - Yi Liu; Xu Xia Zhang; Jia Jia Yu; Chen Liang; Qing Xing; Cong Yao; Chuan You Li (Infectious Diseases, 2020)

Anticancer Activity and Mechanism of Action of kla-TAT Peptide - Xiaolong Chen; Cuihua Hu; Yanan Zhang; Wenjing Hao; Xu He; Qing Li; Yuxi Huang; Yibing Huang; Yuxin Chen (International Journal of Peptide Research and Therapeutics, 2020)

Correction to: The effect of teprenone on the intestinal morphology and microbial community of Chinese sea bass (Lateolabrax maculatus) under intermittent hypoxic stress - Hong-biao Dong; Yong-xu Sun; Ya-fei Duan; Hua Li; Yong Li; Qing-song Liu; Wen-hao Wang; Jia-song Zhang (Fish Physiology and Biochemistry, 2020)

Comparative transcriptome analysis of gynoecious and monoecious inflorescences reveals regulators involved in male flower development in the woody perennial plant Jatropha curcas - Mei-Li Zhao; Mao-Sheng Chen; Jun Ni; Chuan-Jia Xu; Qing Yang; Zeng-Fu Xu (Plant Reproduction, 2020)

Prevalence and Bayesian Phylogenetics of Enteroviruses Derived From Environmental Surveillance Around Polio Vaccine Switch Period in Shandong Province, China - Chenxu Zhao; Xiaojuan Lin; Feng Ji; Ping Xiong; Yao Liu; Suting Wang; Peng Chen; Qing Xu; Li Zhang; Zexin Tao; Aiqiang Xu (Food and Environmental Virology, 2020)

A new oleanane type pentacyclic triterpenoid saponin from the husks of xanthoceras sorbifolium bunge and its neuroprotection on PC12 cells injury induced by Aβ 25-35 - Kewen Ding; Sirui Guo; Weiwei Rong; Qing Li; Ran Liu; Huarong Xu; Yidi Yin; Kaishun Bi (Natural Product Research, 2020)

Zircon U-Pb-Hf isotopes and geochemistry of Jurassic igneous rocks from the southern Zhangguangcai Range, NE China: constraints on magmatism, petrogenesis and tectonic implications - Zuo-Zhen Han; Xiang Ren; Hans-Peter Schertl; Xu-Ping Li; Zhi-Gang Song; Qing-Xiang Du; Chao Han; Wen-Jian Zhong; Li-Hua Gao (International Geology Review, 2020)

The effect of teprenone on the intestinal morphology and microbial community of Chinese sea bass (Lateolabrax maculatus) under intermittent hypoxic stress - Hong-biao Dong; Yong-xu Sun; Ya-fei Duan; Hua Li; Yong Li; Qing-song Liu; Wen-hao Wang; Jia-song Zhang (Fish Physiology and Biochemistry, 2020)

Molecular epidemiology of enteroviruses associated with severe hand, foot and mouth disease in Shenzhen, China, 2014-2018 - Long Chen; Shao-Jian Xu; Xiang-Jie Yao; Hong Yang; Hai-Long Zhang; Jun Meng; Han-Ri Zeng; Xu-He Huang; Ren-Li Zhang; Ya-Qing He (Archives of Virology, 2020)

Protein extraction and database construction in tea rhizosphere soil - Hai-bin Wang; Chun-lian Zhu; Yu-hua Wang; Qing-xu Zhang; Peng Wang; Ding Li; Xiao-li Jia; Jiang-hua Ye; Hai-bin He (Acta Physiologiae Plantarum, 2020)