Enhanced Absorption of Hg2+ by a Recyclable Thiol-Functionalized Salix Psammophila - Qi Shi; Xinglin Yang; Baiyun Zhao; Ze Liu; Yanrong Liu; Xiaokai Liu; Li Wang (Water, Air, & Soil Pollution, 2022)

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

AgMYB12, a novel R2R3-MYB transcription factor, regulates apigenin biosynthesis by interacting with the AgFNS gene in celery - Hao Wang; Jie-Xia Liu; Kai Feng; Tong Li; Ao-Qi Duan; Yan-Hua Liu; Hui Liu; Ai-Sheng Xiong (Plant Cell Reports, 2022)

STAT3-induced NCK1 elevation promotes migration of triple-negative breast cancer cells via regulating ERK1/2 signaling - Peina He; Jianyun Sheng; Jinxu Qi; Xianguang Bai; Jiaxin Li; Fubao Wang; Yamin Yuan; Xinhua Zheng (Molecular Biology Reports, 2022)

QTL mapping and candidate gene mining of flag leaf size traits in Japonica rice based on linkage mapping and genome-wide association study - Jiangxu Wang; Tao Wang; Qi Wang; Xiaodong Tang; Yang Ren; Haiyan Zheng; Kai Liu; Luomiao Yang; Hui Jiang; Yidan Li; Qi Liu; Detang Zou; et al. (Molecular Biology Reports, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

Construction of circRNA-related ceRNA networks in longissimus dorsi muscle of Queshan Black and Large White pigs - Kunlong Qi; Yingke Liu; Chenlei Li; Xinjian Li; Xiuling Li; Kejun Wang; Ruimin Qiao; Xuelei Han (Molecular Genetics and Genomics, 2022)

Effects of cascade reservoir systems on the longitudinal distribution of sediment characteristics: a case study of the Heihe River Basin - Yu Wang; Bao-long Li; Juan-juan Liu; Qi Feng; Wei Liu; Xu Wang; Yu-hua He (Environmental Science and Pollution Research, 2022)
Spatial variations in grain size parameters can reflect river sediment transport patterns and depositional dynamics. Therefore, 22 surficial sediment samples taken from the Heihe River and its cascade reservoirs were analyzed to better understand the impact of cascade reservoir construction on sediment transport patterns in inland rivers in China. The results showed that the longitudinal distribution of sediment grain size in the Heihe River was significantly affected by the influence of the cascade reservoirs. The retention rate in the cascade reservoir of the Heihe River reached 79% (193.53 Mt/year), which caused most of the fine sand to accumulate in the reservoir, and the sediment fining degree reached approximately 50%. However, the water discharged from the dam caused serious erosion of the riverbed and coarsening of the sediment, and the coarsening degree was approximately 500%. The backwater zone of the reservoir was influenced by both backwater and released water, and the coarsening degree of sediment was approximately 101%. Sedimentary environmental analysis revealed that the characteristics of the sediment grain size in an upstream tributary of the Heihe River were more influenced by source material than by hydrodynamic conditions, while the grain size characteristics of the mainstream sediments were controlled mainly by hydrodynamic conditions. The characteristics of sediment transport in different reaches of the Heihe River were studied, and the results may provide references for the operation of cascade reservoirs and the sediment control of reservoirs.

The Protective Effect of Selenium on T-2-Induced Nephrotoxicity Is Related to the Inhibition of ROS-Mediated Apoptosis in Mice Kidney - Xuliang Zhang; Qi Wang; Jian Zhang; Miao Song; Bing Shao; Yanfei Han; Xu Yang; Yanfei Li (Biological Trace Element Research, 2022)

Effect of feed restriction on the intestinal microbial community structure of growing ducks - Jun-peng Li; Qi-fan Wu; Sheng-chao Ma; Jian-mei Wang; Bin Wei; Yang Xi; Chun-chun Han; Liang Li; Hua He; He-he Liu (Archives of Microbiology, 2022)

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

Application of microbially induced calcium carbonate precipitation (MICP) in sand embankments for scouring/erosion control - Zhaoyu Wang; Nan Zhang; Yong Jin; Qi Li; Junhao Xu (Marine Georesources & Geotechnology, 2021)

Spatiotemporal characteristics of human activity on coastal landscape of Laizhou Bay - Fan Yang; Jie Li; Jiaqing Wang; Jiantao Huang; Tong Qi; Yiman Liu; Tianyu Fu; Shuting Yu; Lingyan Zhao (Wetlands Ecology and Management, 2021)

The decreased expression of GW2 homologous genes contributed to the increased grain width and thousand‑grain weight in wheat-Dasypyrum villosum 6VS·6DL translocation lines - Zhiyu Feng; Long Song; Wanjun Song; Zhongqi Qi; Jun Yuan; Run Li; Haiming Han; Huifang Wang; Zhaoyan Chen; Weilong Guo; Mingming Xin; Jie Liu; et al. (Theoretical and Applied Genetics, 2021)

Enlightenment about using TCM constitutions for individualized medicine and construction of Chinese-style precision medicine: research progress with TCM constitutions - Lingru Li; Zhenyu Wang; Ji Wang; Yanfei Zheng; Yingshuai Li; Qi Wang (Science China Life Sciences, 2021)

Recombinant Avian β-Defensin Produced by Food-Grade Lactococcus as a Novel and Potent Immunological Enhancer Adjuvant for Avian Vaccine - Tingting Wang; Zhihao Wang; Jielan Mi; Wenqian Wang; Kai Li; Xiaole Qi; Yulong Gao; Li Gao; Changjun Liu; Yanping Zhang; Qing Pan; Xiaomei Wang; et al. (Probiotics and Antimicrobial Proteins, 2021)
In this study, we expressed rAvBD1-2–6-13 protein through Lactococcus lactis NZ3900, and the effects of the recombinant L. lactis NZ3900 as an immune enhancer and immune adjuvant were verified using in vivo and in vitro tests. In vitro tests revealed that recombinant L. lactis NZ3900 significantly activated the NF-κB signaling pathway and IRF signaling pathway in J774-Dual™ report cells and significantly increased the transcript levels of IL-10, IL-12p70, CD80, and CD86 in chicken PBMCs and chicken HD11 cells. In vivo experiments revealed that the immunized group supplemented with recombinant L. lactis NZ3900 as an adjuvant had significantly higher serum antibody titers and higher proliferative activity of PBMCs in the blood of the chickens immunized with NDV live and inactivated vaccines. Our study shows that the recombinant L. lactis NZ3900 has strong immunomodulatory activity both in vivo and in vitro and is a potential immune enhancer. Our work lays the foundation for the research and development of new animal immune enhancers for application in the poultry industry.

Transcriptome-based identification and expression profiling of AP2/ERF members in Caragana intermedia and functional analysis of CiDREB3 - Kun Liu; Qi Yang; Tianrui Yang; Feiyun Yang; Ruigang Wang; Jingyu Cong; Guojing Li (Molecular Biology Reports, 2021)

Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum–Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats - Kokwin Ooi; Li Hu; Yi Feng; Chenzhi Han; Xiaorong Ren; Xinyi Qian; Haofeng Huang; Sijia Chen; Qi Shi; Hong Lin; Jijiang Wang; Danian Zhu; et al. (Molecular Neurobiology, 2021)

MicroRNA-197-3p mediates damage to human coronary artery endothelial cells via targeting TIMP3 in Kawasaki disease - Chaowu Liu; Deguang Yang; Hong Wang; Shengwei Hu; Xiaofei Xie; Li Zhang; Hongling Jia; Qi Qi (Molecular and Cellular Biochemistry, 2021)

Analysis of the current activity of the Red River fault based on GPS data: new seismological inferences - XiaoFei Lu; Kai Tan; Qi Li; Chengtao Li; Dongzhen Wang; Caihong Zhang (Journal of Seismology, 2021)

Hydrogen Sulfide–Phytohormone Interaction in Plants Under Physiological and Stress Conditions - Zhong-Guang Li; Ru-Hua Xiang; Jia-Qi Wang (Journal of Plant Growth Regulation, 2021)

Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology - Yuhong Zhang; Xu Chen; Qiqi Wang; Congcong Du; Wenbin Lu; Hong Yuan; Zhenzhen Zhang; Danqing Li; Xing Ling; Xiang Ren; Yang Zhao; Qi Su; et al. (Journal of Molecular Medicine, 2021)

c-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3β Survival Pathway - Cong Yan; Hongwei Yu; Yao Liu; Pei Wu; Chunlei Wang; Hongbo Zhao; Kongbin Yang; Qi Shao; Yingqiang Zhong; Wenyang Zhao; Jingwei Li; Nan Liu; et al. (Journal of Molecular Neuroscience, 2021)

Allelopathically inhibitory effects of 5,4′-dihydroxyflavone on the growth, antioxidant system and photosynthesis of the bloom-forming cyanobacterium Microcystis aeruginosa - Jie Wang; Ying Shi; Meng Zhang; Yanhui Li; Qi Liu; Shulian Xie (Journal of Applied Phycology, 2021)

Detoxification difference of cadmium between the application of selenate and selenite in native cadmium-contaminated soil - Mingxing Qi; Yang Liu; Yanan Li; Min Wang; Nana Liu; Pornpimol Kleawsampanjai; Fei Zhou; Hui Zhai; Mengke Wang; Quang Toan Dinh; Rui Ren; Dongli Liang (Environmental Science and Pollution Research, 2021)

Dissimilatory nitrate reduction and functional genes in two subtropical rivers, China - Binjie Zhao; Xinshuai Li; Yang Wang; Xiang Tan; Wenhua Qi; Hongran Li; Junwei Wei; Yong You; Wenjun Shi; Quanfa Zhang (Environmental Science and Pollution Research, 2021)

Analysis of the starch properties in tetraploid wheat–Aegilops sharonensis amphidiploid - Qing Li; Xuteng Zhang; Na Lin; Guzmán Carlos; Jingyu Lan; Huaping Tang; Pengfei Qi; Jian Ma; Jirui Wang; Guoyue Chen; Wei Li; Zhien Pu; et al. (Cereal Research Communications, 2021)

Geochemical characteristics and genesis of deep marine carbonate natural gas in China - Jianglong Shi; Jian Li; Jin Li; Aisheng Hao; Zhongsheng Shi; Bin Zhang; Bin Hao; Xuening Qi; Bintao Chen; Luo Xue; Lun Ma; Lei Wang; et al. (Carbonates and Evaporites, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Halomonas salipaludis sp. nov., isolated from a saline-alkali wetland soil - Juyuan Xing; Qi Gong; Liu Tang; Jiao Li; Hua Fan; Xiaowei Wang; Hongxia Liu; Guishan Zhang; Jinxing Zhu (Archives of Microbiology, 2021)

Stress response mechanisms and description of three novel species Shewanella avicenniae sp. nov., Shewanella sedimentimangrovi sp. nov. and Shewanella yunxiaonensis sp. nov., isolated from mangrove ecosystem - Guo-Hong Liu; Qi Zhang; Manik Prabhu Narsing Rao; Shang Yang; Rong Tang; Huai Shi; Jie-Ping Wang; Guan-Min Huang; Bo Liu; Shun-Gui Zhou; Wen-Jun Li (Antonie van Leeuwenhoek, 2021)

Immersion immunization of common carp with bacterial ghost‐based DNA vaccine inducing prophylactic protective immunity against spring viraemia of carp virus - Yu‐Ying Zheng; Chen Zhang; Yang Li; Peng‐Qi Zhang; Guo Chen; Gao‐Xue Wang; Bin Zhu (Journal of Fish Diseases, 2021)
The interactive applications of immunization route, vaccine type and delivery vectors are emerging as a key area of research within the field of mass immunization in fishery production. In an effort to improve DNA vaccine's immune efficiency in large‐scale immunization, a promising bacterial ghost‐loaded DNA vaccine was constructed based on Escherichia coli DH5α. In common carp was investigated the immune response to immersion immunization via related indicator analysis, and the challenge test of spring viraemia of carp virus (SVCV) was carried out. The result indicated that BG‐loaded DNA vaccine induced higher serum antibody level than naked pEG‐G. Simultaneously, the immunophysiological indicators and genes change at the more advanced levels in the BG/pEG‐G immune group. At the treatment concentration of 20 mg/L of the BG/pEG‐G group, IgM and IgZ expressions in vivo were markedly increased by 21.62 times and 6.91 times, respectively, and the relative percentage survival reached the peak of 59.57%. This study paves the way for future aquatic animal vaccine research, which aimed to develop the highly effective immersion vaccine system by delivery vectors, with the ultimate aim to prevent and restrict SVCV in actual production.

Warming reshaped the microbial hierarchical interactions - Yuqi Zhou; Baoyu Sun; Baohua Xie; Kai Feng; Zhaojing Zhang; Zheng Zhang; Shuzhen Li; Xiongfeng Du; Qi Zhang; Songsong Gu; Wen Song; Linlin Wang; et al. (Global Change Biology, 2021)
Global warming may alter microbially mediated ecosystem functions through reshaping of microbial diversity and modified microbial interactions. Here, we examined the effects of 5‐year experimental warming on different microbial hierarchical groups in a coastal nontidal soil ecosystem, including prokaryotes (i.e., bacteria and archaea), fungi, and Cercozoa, which is a widespread phylum of protists. Warming significantly altered the diversity and structure of prokaryotic and fungal communities in soil and additionally decreased the complexity of the prokaryotic network and fragmented the cercozoan network. By using the Inter‐Domain Ecological Network approach, the cross‐trophic interactions among prokaryotes, fungi, and Cercozoa were further investigated. Under warming, cercozoan–prokaryotic and fungal–prokaryotic bipartite networks were simplified, whereas the cercozoan–fungal network became slightly more complex. Despite simplification of the fungal–prokaryotic network, the strengthened synergistic interactions between saprotrophic fungi and certain prokaryotic groups, such as the Bacteroidetes, retained these phyla within the network under warming. In addition, the interactions within the fungal community were quite stable under warming conditions, which stabilized the interactions between fungi and prokaryotes or protists. Additionally, we found the microbial hierarchical interactions were affected by environmental stress (i.e., salinity and pH) and soil nutrients. Interestingly, the relevant microbial groups could respond to different soil properties under ambient conditions, whereas under warming these two groups tended to respond to similar soil properties, suggesting network hub species responded to certain environmental changes related to warming, and then transferred this response to their partners through trophic interactions. Finally, warming strengthened the network modules’ negative association with soil organic matters through some fungal hub species, which might trigger soil carbon loss in this ecosystem. Our study provides new insights into the response and feedback of microbial hierarchical interactions under warming scenario.

Terpenoids with neurotrophic and anti-neuroinflammatory activities from the cultures of the fungus Cyathus stercoreus - Xia Yin; Jianzhao Qi; Yixiao Li; Ze’an Bao; Peng Du; Rongwei Kou; Weiwei Wang; Jin-Ming Gao (Natural Product Research, 2021)

Two new 7, 20-epoxy- ent -kauranes from the aerial parts of Isodon eriocalyx - Shu-Ying Li; Li-Hua Zhu; Zheng-Yun Rao; Chao-Jun Wang; Min Jiang; Jian Zhang; Zhi-Qi Yin (Natural Product Research, 2021)

Sociohydrology: An Effective Way to Reveal the Coupled Evolution of Human and Water Systems - Jiali Gu; Shikun Sun; Yubao Wang; Xiaojuan Li; Yali Yin; Jingxin Sun; Xinyu Qi (Water Resources Management, 2021)

Hydrogen-rich water promotes the formation of bulblets in Lilium davidii var. unicolor through regulating sucrose and starch metabolism - Xuemei Hou; Nana Qi; Chunlei Wang; Changxia Li; Dengjing Huang; Yihua Li; Ni Wang; Weibiao Liao (Planta, 2021)

Effect of coronatine on synthesis of cephalotaxine in suspension cells of Cephalotaxus mannii and its transcriptome analysis - Liu-Yan Wang; Qiao Zhang; Zi-Qi Wang; Yong-Cheng Li (Plant Cell, Tissue and Organ Culture (PCTOC), 2021)

Genetic Prion Disease: Insight from the Features and Experience of China National Surveillance for Creutzfeldt-Jakob Disease - Qi Shi; Cao Chen; Kang Xiao; Wei Zhou; Li-Ping Gao; Dong-Dong Chen; Yue-Zhang Wu; Yuan Wang; Chao Hu; Chen Gao; Xiao-Ping Dong (Neuroscience Bulletin, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Optimization of 4D flow MRI velocity field in the aorta with divergence-free smoothing - Qi Gao; Xingli Liu; Hongping Wang; Peng Wu; Mansu Jin; RunJie Wei; Wei Wang; Zhaozhuo Niu; Shihua Zhao; Fei Li (Medical & Biological Engineering & Computing, 2021)

A 168-year temperature recording based on tree rings and latitude differences in temperature changes in northeast China - Yangao Jiang; Yuting Cao; Junhui Zhang; Zhuo Li; Guoqiang Shi; Shijie Han; Cassius E. O. Coombs; Chuan Liu; Xiaoguang Wang; Junwei Wang; Lin Hao; Qi Xu; et al. (International Journal of Biometeorology, 2021)

Ecological risk assessment of heavy metals in farmland soils in Beijing by three improved risk assessment methods - Rui Chen; Xuying Cai; Guoyu Ding; Fumin Ren; Qi Wang; Nuo Cheng; Jiaxing Liu; Lanxin Li; Rongguang Shi (Environmental Science and Pollution Research, 2021)

Do China’s coal-to-gas policies improve regional environmental quality? A case of Beijing - Jianliang Wang; Zonghan Li; Hongkai Ye; Yingdan Mei; Jiaxin Fu; Qi Li (Environmental Science and Pollution Research, 2021)

Genome mining of secondary metabolites from a marine-derived Aspergillus terreus B12 - Xinyang Du; Huanhuan Li; Jiangfeng Qi; Chaoyi Chen; Yuanyuan Lu; Ying Wang (Archives of Microbiology, 2021)

Suppressed Thermocline Mixing in the Center of Anticyclonic Eddy in the North South China Sea - Yongfeng Qi; Huabin Mao; Xia Wang; Linhui Yu; Shumin Lian; Xianpeng Li; Xiaodong Shang (Journal of Marine Science and Engineering, 2021)
Direct microstructure observations and fine-scale measurements of an anticyclonic mesoscale eddy were conducted in the northern South China Sea in July 2020. An important finding was that suppressed turbulent mixing in the thermocline existed at the center of the eddy, with an averaged diapycnal diffusivity at least threefold smaller than the peripheral diffusivity. Despite the strong background shear and significant wave–mean flow interactions, the results indicated that the lack of internal wave energy in the corresponding neap tide period during measurement of the eddy’s center was the main reason for the suppressed turbulent mixing in the thermocline. The applicability of the fine-scale parameterization method in the presence of significant wave–mean flow interactions in a mesoscale eddy was evaluated. Overprediction via fine-scale parameterization occurred in the center of the eddy, where the internal waves were inactive; however, the parameterization results were consistent with microstructure observations along the eddy’s periphery, where active internal waves existed. This indicates that the strong background shear and wave–mean flow interactions affected by the mesoscale eddy were not the main contributing factors that affected the applicability of fine-scale parameterization in the northern South China Sea. Instead, our results showed that the activity of internal waves is the most important consideration.

A new triterpenoid and other constituents with cytotoxic activity from the roots of Sanguisorba officinalis L - Rongshen Wang; Jinfeng Sun; Mei Jin; Lan Jin; Yanqiu Qi; Lihua Cao; Wei Zhou; Gao Li (Natural Product Research, 2021)

Expression of the SPL-like gene LaSPL9 in Japanese larch (Larix leptolepis) is regulated by miR156 during somatic embryogenesis - Li-feng Zhang; Yan-ru Fan; Qian Lan; Li-wang Qi; Su-ying Han (Trees, 2021)

Urban nocturnal cooling mediated by bluespace - Yuanfeng Cui; Leiqiu Hu; Zhihua Wang; Qi Li (Theoretical and Applied Climatology, 2021)

Single cell transcriptomic analysis identifies novel vascular smooth muscle subsets under high hydrostatic pressure - Zhenzhen Chen; Haizeng Zhang; Yingnan Bai; Changting Cui; Shuangyue Li; Wenjie Wang; Yue Deng; Qiannan Gao; Lu Wang; Wei Qi; Lijun Zhang; Yan Yang; et al. (Science China Life Sciences, 2021)

SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function - Xiangyu Xu; Yu Cui; Congqin Li; Yuyang Wang; Jing Cheng; Songfeng Chen; Jiangdong Sun; Jinyang Ren; Xujin Yao; Jingchen Gao; Xiaohong Huang; Qi Wan; et al. (Molecular Neurobiology, 2021)

The severe toxicity of CuO nanoparticles to the photosynthesis of the prokaryotic algae Arthrospira sp - Xingkai Che; Ruirui Ding; Qiang Zhang; Yujie Li; Qi Sun; Yuting Li; Zishan Zhang; Wei Wang; Huiyuan Gao (Environmental Science and Pollution Research, 2021)

Release characteristics of inorganic nitrogen in different water layers and its impact on overlying water from Liaohe River, China - Chen Qiuying; Wang Qi; Li Zhidong; Zhang Mingwei; Sun Manzhong (Ecotoxicology, 2021)

Water resources response and prediction under climate change in Tao’er River Basin, Northeast China - Jia-qi Sun; Hong-yan Li; Xiao-jun Wang; Shamsuddin Shahid (Journal of Mountain Science, 2021)

A comparative analysis of navigation signals in BDS-2 and BDS-3 using zero-baseline experiments - Chenlong Deng; Shufeng Qi; Yangyang Li; Yawei Wang; Xuan Zou; Weiming Tang; Chi Guo (GPS Solutions, 2021)

Correction to: Development of a GNSS‑IR instrument based on low‑cost positioning chips and its performance evaluation for estimating the reflector height - Yunwei Li; Kegen Yu; Taoyong Jin; Xin Chang; Qi Wang; Jiancheng Li (GPS Solutions, 2021)

Development of a GNSS-IR instrument based on low-cost positioning chips and its performance evaluation for estimating the reflector height - Yunwei Li; Kegen Yu; Taoyong Jin; Xin Chang; Qi Wang; Jiancheng Li (GPS Solutions, 2021)

Ambient climate determines the directional trend of community stability under warming and grazing - Peipei Liu; Wangwang Lv; Jianping Sun; Caiyun Luo; Zhenhua Zhang; Xiaoxue Zhu; Xingwu Lin; Jichuang Duan; Guangping Xu; Xiaofeng Chang; Yigang Hu; Qiaoyan Lin; et al. (Global Change Biology, 2021)
Changes in ecological processes over time in ambient treatments are often larger than the responses to manipulative treatments in climate change experiments. However, the impacts of human‐driven environmental changes on the stability of natural grasslands have been typically assessed by comparing differences between manipulative plots and reference plots. Little is known about whether or how ambient climate regulates the effects of manipulative treatments and their underlying mechanisms. We collected two datasets, one a 36‐year long‐term observational dataset from 1983 to 2018, and the other a 10‐year manipulative asymmetric warming and grazing experiment using infrared heaters with moderate grazing from 2006 to 2015 in an alpine meadow on the Tibetan Plateau. The 36‐year observational dataset shows that there was a nonlinear response of community stability to ambient temperature with a positive relationship between them due to an increase in ambient temperature in the first 25 years and then a decrease in ambient temperature thereafter. Warming and grazing decreased community stability with experiment duration through an increase in legume cover and a decrease in species asynchrony, which was due to the decreasing background temperature through time during the 10‐year experiment period. Moreover, the temperature sensitivity of community stability was higher under the ambient treatment than under the manipulative treatments. Therefore, our results suggested that ambient climate may control the directional trend of community stability while manipulative treatments may determine the temperature sensitivity of the response of community stability to climate relative to the ambient treatment. Our study emphasizes the importance of the context dependency of the response of community stability to human‐driven environmental changes.

Mapping QTL for seedling morphological and physiological traits under normal and salt treatments in a RIL wheat population - Qiaoling Luo; Pan Hu; Guotang Yang; Hongwei Li; Liqin Liu; Zishan Wang; Bin Li; Zhensheng Li; Qi Zheng (Theoretical and Applied Genetics, 2021)

Genomic structural equation modelling provides a whole-system approach for the future crop breeding - Tianhua He; Tefera Tolera Angessa; Camilla Beate Hill; Xiao-Qi Zhang; Kefei Chen; Hao Luo; Yonggang Wang; Sakura D. Karunarathne; Gaofeng Zhou; Cong Tan; Penghao Wang; Sharon Westcott; et al. (Theoretical and Applied Genetics, 2021)

A Frameshift Variant in the SEMA6B Gene Causes Global Developmental Delay and Febrile Seizures - Li Shu; Yuchen Xu; Qi Tian; Yuanyuan Chen; Yaqin Wang; Hui Xi; Hua Wang; Neng Xiao; Xiao Mao (Neuroscience Bulletin, 2021)

Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson’s disease: a systematic review and meta-analysis - De-Qi Jiang; Qing-Min Zang; Li-Lin Jiang; Yan Wang; Ming-Xing Li; Jing-Yi Qiao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

A Rare Variation in the 3’ Untranslated Region of the Presenilin 2 Gene Is Linked to Alzheimer’s Disease - Yana Pang; Tingting Li; Qi Wang; Wei Qin; Ying Li; Yiping Wei; Longfei Jia (Molecular Neurobiology, 2021)

CircUBQLN1 Promotes Proliferation but Inhibits Apoptosis and Oxidative Stress of Hippocampal Neurons in Epilepsy via the miR-155-Mediated SOX7 Upregulation - Zhujun Zhu; Sihong Wang; Qi Cao; Gang Li (Journal of Molecular Neuroscience, 2021)

Transcriptome sequencing of wild soybean revealed gene expression dynamics under low nitrogen stress - Qi Sun; Haoran Lu; Qing Zhang; Di Wang; Jun Chen; Jialei Xiao; Xiaodong Ding; Qiang Li (Journal of Applied Genetics, 2021)

Protective Effects of Pidotimod Against Salmonella Infections - Yuanhao Zhou; Xiaolin Ye; Baikui Wang; Jiafu Ying; Zihan Zeng; Li Tang; Qi Wang; Peng Zou; Xiaoli Zhan; Luoqin Fu (International Journal of Peptide Research and Therapeutics, 2021)

Comparative responses of cadmium accumulation and subcellular distribution in wheat and rice supplied with selenite or selenate - Kang Wang; Jingying Linghu; Lingxuan Kong; Siyu Huang; Qi Wang; Huafen Li; Yanan Wan (Environmental Science and Pollution Research, 2021)

Analysis of wet deposition characteristics in the city of Guilin, China - Qi Feng; Youling Li; Jianhui Wen; Hongqiang Wang; Lei Liao (Environmental Monitoring and Assessment, 2021)

Microbiogenic thrombolites from the Cambrian Miaolingian Series of southern North China Craton - Xiaofang Sun; Mingyue Dai; Yong’an Qi; Bingchen Liu; Wei Zheng; Zhifeng Xing; Min Wang; Da Li; Yuchao Fan (Carbonates and Evaporites, 2021)

A leucoanthocyanidin dioxygenase gene (RtLDOX2) from the feral forage plant Reaumuria trigyna promotes the accumulation of flavonoids and improves tolerance to abiotic stresses - Ningning Li; Xue Wang; Binjie Ma; Zhigang Wu; Linlin Zheng; Zhi Qi; Yingchun Wang (Journal of Plant Research, 2021)

Characteristics of airborne microbial community in Hefei, eastern China, under a good quality in mid-spring - Li Wang; Changnian Wu; Qi Ling; Jiangying Yu; Weihua Li; Weiyue Wang; Jinkang Zhao (Aerobiologia, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

Long-Endurance Dynamic Path Planning Method of NSV Considering Wind Energy Capture - Qi Jia; Yulei Liao; Peihong Xu; Zixiao Wang; Shuo Pang; Xiangjie Li (Journal of Marine Science and Engineering, 2021)
To meet the mission requirements of long-endurance and unmanned marine environment observation, the natural energy-driven unmanned surface vehicle (NSV) usually takes special sailing paths to increase energy capture to achieve the purpose of improving endurance. Aiming at the route planning problems of the “Wave Rider” NSV in the time-varying ocean wind field, this paper is organized as follows. Firstly, a visual modeling method of the real-time-varying ocean wind field for NSV is proposed. Then, through the wind energy capture experiment, the NSV system energy net output model is calculated, and a Dynamic Dijkstra algorithm considering wind energy capture (DW–Dijkstra) has been proposed in this paper based on a Dijkstra algorithm, of which weight function has been improved. Accordingly, the NSV long-endurance dynamic path planning method is designed. Finally, the DW–Dijkstra algorithm has been verified through a set of comparison simulations and a set of semi-physical comparison simulations. The results show that the DW–Dijkstra algorithm can plan a collision-free and high-efficiency energy capture path in the real-time-varying ocean wind field environment in the southern waters of China. Compared with the traditional A* algorithm and the Wind_A* algorithm, the proposed method can save energy by between 15.07% and 6.50%, respectively, which effectively increases the endurance of the NSV.

Paleoproterozoic S-type granites in the Lengshui complex, South China: Implications for the tectonic evolution of the Yangtze Block - Kuizhou Li; Qi Deng; Jian Wang; Chris Yakymchuk; Mingcai Hou; Xiaozhuang Cui; Guangming Ren; Fei Ren; Wen Luo (International Geology Review, 2021)

Identification and mapping of CpPM10.1, a major gene involved in powdery mildew (race 2 France of Podosphaera xanthii) resistance in zucchini (Cucurbita pepo L.) - Yunli Wang; Cong Qi; Yusong Luo; Feng Zhang; Zuyun Dai; Man Li; Shuping Qu (Theoretical and Applied Genetics, 2021)

Identification and function analysis of fasciclin-like arabinogalactan protein family genes in pear (Pyrus bretschneideri) - Xiaoqiang Li; Mengyu Cheng; Chao Tang; Xiaoxuan Zhu; Kaijie Qi; Shaoling Zhang; Juyou Wu; Peng Wang (Plant Systematics and Evolution, 2021)

LncRNA MYCNOS promotes glioblastoma cell proliferation by regulating miR-216b/FOXM1 axis - Ping Zhao; Ting Li; Youliang Wang; Yong Wang; Qi Gu; Zhi Li (Metabolic Brain Disease, 2021)

Autophagy blockage promotes the pyroptosis of ox-LDL-treated macrophages by modulating the p62/Nrf2/ARE axis - Jiaru Liu; Chao Wang; Jiashan Li; Ying Yu; Yuee Liu; Huihui Liu; Qi Peng; Xiuru Guan (Journal of Physiology and Biochemistry, 2021)

miR-455-5p regulates atrial fibrillation by targeting suppressor of cytokines signaling 3 - Weiling Li; Na Qi; Shuo Wang; Wenyan Jiang; Tao Liu (Journal of Physiology and Biochemistry, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Transcriptome analysis reveals the importance of exogenous nutrition in regulating antioxidant defenses during the mouth-opening stage in oviparous fish - Hao Xu; Shi-Qi Fan; Guo Wang; Xiao-Min Miao; Yun Li (Fish Physiology and Biochemistry, 2021)

Gonadal lipidomics profile of an ovoviviparity teleost, black rockfish, during gonadal development - Jianshuang Li; Min Song; Haishen Wen; Ying Zhang; Yun Li; Likang Lyu; Xiaojie Wang; Xin Qi (Fish Physiology and Biochemistry, 2021)

The comparative impact among different intensive statins and combination therapies with niacin/ezetimibe on carotid intima-media thickness: a systematic review, traditional meta-analysis, and network meta-analysis of randomized controlled trials - Hongwei Li; Xiaolin Xu; Liming Lu; Runlu Sun; Qi Guo; Qian Chen; Junjie Wang; Zhijian He; Yuling Zhang (European Journal of Clinical Pharmacology, 2021)

Associations of Dietary Exposure to Organochlorine Pesticides from Plant-Origin Foods with Lipid Metabolism and Inflammation in Women: A Multiple Follow-up Study in North China - Xuepeng Wang; Miaomiao Gao; Yixi Tan; Qi Li; Junxi Chen; Changxin Lan; Bahabieke Jiangtulu; Bin Wang; Guofeng Shen; Yanxin Yu; Zhiwen Li (Bulletin of Environmental Contamination and Toxicology, 2021)

Terpenoids from the South China Sea soft coral Sinularia multiflora - Zheng Wang; Ping-Lin Li; Xiang-Chao Luo; Qi Wang; Leen van Ofwegen; Xu-Li Tang; Guo-Qiang Li (Natural Product Research, 2021)

Screening lager yeast with higher ethyl-acetate production by adaptive laboratory evolution in high concentration of acetic acid - Xin Xu; Chengtuo Niu; Chunfeng Liu; Jinjing Wang; Feiyun Zheng; Qi Li (World Journal of Microbiology and Biotechnology, 2021)

Metabolic energy variation of yeast affects its antioxidant properties in beer brewing - Jinjing Wang; Xuerong Fu; Mengqi Li; Feiyun Zheng; Chengtuo Niu; Chunfeng Liu; Qi Li (Systems Microbiology and Biomanufacturing, 2021)

Roles and Mechanisms of Axon-Guidance Molecules in Alzheimer’s Disease - Lei Zhang; Zhipeng Qi; Jiashuo Li; Minghui Li; Xianchao Du; Shuang Wang; Guoyu Zhou; Bin Xu; Wei Liu; Shuhua Xi; Zhaofa Xu; Yu Deng (Molecular Neurobiology, 2021)

Maternal exposure to O3 and NO2 may increase the risk of newborn congenital hypothyroidism: a national data-based analysis in China - Cuifang Qi; Li Shang; Wenfang Yang; Liyan Huang; Liren Yang; Juan Xin; Shanshan Wang; Jie Yue; Lingxia Zeng; Mei Chun Chung (Environmental Science and Pollution Research, 2021)
Maternal exposure to air pollution during pregnancy is associated with adverse outcomes in the offspring, but limited studies focused on the impacts of gaseous air pollution on newborn congenital hypothyroidism (CH). Therefore, a national data-based analysis was conducted to explore the association between maternal exposure to gaseous air pollution and the incidence of CH in China. Annual average exposure levels of SO 2 , NO 2 , CO, and O 3 from January 1, 2014, to December 30, 2014, were acquired from the Chinese Air Quality Online Monitoring and Analysis Platform. The annual incidence of newborn CH from October 1, 2014, to September 30, 2015, was collected from the Chinese Maternal and Child Health Surveillance Network. Temperature and toxic metal in wastewater in 2014 were also collected as covariates. Maternal exposure to O 3 and NO 2 in 1 μg/m 3 level increment was positively associated with newborn CH, with an OR of 1.055 (95% CI 1.011, 1.102) and 1.097 (95% CI 1.019, 1.182) after adjusting for covariates completely. Compared with the lowest level of O 3 , maternal exposure to the 4th quartile of O 3 was positively associated with newborn CH (OR 1.393, 95% CI 1.081, 1.794) after adjusting for covariates completely. And the 3rd and 4th quartiles of NO 2 were associated positively with CH (OR 1.576, 95% CI 1.025, 2.424, and OR 1.553, 95% CI 0.999, 2.414, respectively) compared with the lowest level of NO 2 . By fitting the ROC curve, 93.688 μg/m 3 in O 3 might be used as cutoff to predict the incidence of newborn CH in China.

Programmed sequential cutting endows Cas9 versatile base substitution capability in plants - Wei Yang; Wei Qi; Yucai Li; Jiyao Wang; Yanmin Luo; Dehui Ding; Sudong Mo; Bo Chen; Yu Lu; Huarong Li; Linjian Jiang (Science China Life Sciences, 2021)

The impacts of base level and lithology on fluvial geomorphic evolution at the tectonically active Laohu and Hasi Mountains, northeastern Tibetan Plateau - Zhengchen Li; Xianyan Wang; Yang Yu; Huiping Zhang; Qi Su; Xiaodong Miao; Huayu Lu (Science China Earth Sciences, 2021)

Analysis of the Promoter of Emb5 from Zea mays Identifies a Region of 523 bp Responsible for Its Embryo-Specific Activity - Yang Li; Liping Yu; Qiushuang Wang; Xiangyu Zhao; Xinzheng Li; Baoxiu Qi (Plant Molecular Biology Reporter, 2021)
The maize Emb5 is an abscisic acid–responsive gene which is specifically expressed in the late embryo during seed maturity. To further dissect and identify the elements specific for its embryo expression pattern, we investigated the activity of the − 1653 bp upstream of the “full-length” promoter region of this gene in transgenic Arabidopsis plants. We first confirmed that the “full-length” promoter could indeed drive the expression of β-glucuronidase reporter gene ( GUS ) in the transgenic Arabidopsis seed embryo. Subsequently, DNA fragments of ~ 500 bp in length were generated after a series of progressive deletions from positions − 1653 bp to − 1 bp relative to the transcriptional initiation site. These fragments were fused with GUS and introduced into Arabidopsis. Measurement of the GUS activity in the immature seeds isolated from the transgenic plants revealed that the region between positions − 523 bp and − 1 bp, namely Pro Em-D, is absolutely required and sufficient for the temporal and embryo-specific expression of GUS with an activity comparable with the full-length Emb5 promoter in Arabidopsis. Therefore, our results clearly demonstrated that the 523 bp Pro Em-D can replace the − 1653 bp Emb5 promoter to drive embryo-specific expression in Arabidopsis seed. Because of its small size and strong embryo-specific activity, it could become the promoter of choice in metabolic pathway engineering to transfer multiple genes for the production of valuable pharmaceutical products in seeds, such as polyunsaturated fatty acids found in fish oils, or pro-vitamin A where at least three transgenes are required to assemble the entire metabolic pathways.

Mapping Domain- and Age-Specific Functional Brain Activity for Children’s Cognitive and Affective Development - Lei Hao; Lei Li; Menglu Chen; Jiahua Xu; Min Jiang; Yanpei Wang; Linhua Jiang; Xu Chen; Jiang Qiu; Shuping Tan; Jia-Hong Gao; Yong He; et al. (Neuroscience Bulletin, 2021)

SR-B1 and CD10 combined immunoprofile for differential diagnosis of metastatic clear cell renal cell carcinoma and clear cell carcinoma of the ovary - Teng Jiang; Xiaoli Diao; Meili Ding; Xiao Niu; Chao Wang; Yan Qi; Wei Jia; Lijuan Pang; Wenhao Hu; Hong Zou; Feng Li (Journal of Molecular Histology, 2021)
Both clear cell renal carcinoma (ccRCC) and clear cell carcinoma of the ovary (CCOC) have a clear cytoplasmic morphological feature, hence it is difficult to identify metastatic ccRCC and CCOC by morphology alone. At present, there are no effective immunohistochemical markers to distinguish between these two tumors. Studies have shown that the clear cytoplasm of ccRCC is mainly caused by cholesterol-rich lipids in the cytoplasm, while that of CCOC is due to the accumulation of cytoplasmic glycogen. Objective: to hypothesize that the scavenger receptor class B-type 1 (SR-B1) protein responsible for HDL cholesterol uptake may be differentially expressed in ccRCC and CCOC, and high CD10 expression in the renal tubular epithelium may assist in distinguishing between ccRCC and CCOC. Methods: effective immunohistochemical markers were applied in 90 cases of renal clear cell carcinoma and 31 cases of ovarian cancer to distinguish between the two types of tumors.Result: SR-B1 and CD10 expression is significantly higher in ccRCC than CCOC. Both SR-B1 and CD10 exhibited focal weak-medium intensity staining in CCOC, and their staining extent and intensity were significantly lower than ccRCC. The sensitivity and specificity of SR-B1 for identifying ccRCC were 74.4% and 83.9%, respectively. The sensitivity and specificity of CD10 for identifying CCOC were 93.3% and 80.6%, respectively. The combined SR-B1( +) CD10( +) immunoprofile supports the diagnosis of ccRCC with a specificity of 93.5%. The combined SR-B1(-) CD10(-) immunoprofile supports the diagnosis of CCOC with a specificity of 93.3%. Conclusions: our findings demonstrate that the combination of SR-B1 and CD10 immunoprofiling is a valuable tool for differential diagnosis of ccRCC and CCOC.

Genome-Wide Investigation of Major Enzyme-Encoding Genes in the Flavonoid Metabolic Pathway in Tartary Buckwheat (Fagopyrum tataricum) - Yingjun Yao; Lei Sun; WenJing Wu; Shuang Wang; Xin Xiao; MinLun Hu; ChengLei Li; HaiXia Zhao; Hui Chen; Qi Wu (Journal of Molecular Evolution, 2021)

Seasonal variation of nitrogen biogeochemical processes constrained by nitrate dual isotopes in cascade reservoirs, Southwestern China - Sai-Nan Chen; Fu-Jun Yue; Xiao-Long Liu; Jun Zhong; Yuan-Bi Yi; Wan-Fa Wang; Yulin Qi; Hua-Yun Xiao; Si-Liang Li (Environmental Science and Pollution Research, 2021)

Anticancer effect of sodium metavanadate on murine breast cancer both in vitro and in vivo - Yu Tian; Haihui Qi; Gang Wang; Li Li; Dinglun Zhou (BioMetals, 2021)

LAI scale effect research based on compact airborne spectrographic imager data in the Heihe Oasis - Xiao-ai Dai; Chao Liu; Nai-wen Li; Mei-lian Wang; Yu-wei Yang; Xing-ping Yang; Shi-qi Zhang; Xu-wei He; Zheng-li Yang; Heng Lu; Jing-zhong Li; Ze-kun Wang (Journal of Mountain Science, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Wave Dissipation and Sediment Transport Patterns during Shoreface Nourishment towards Equilibrium - Yuan Li; Chi Zhang; Yu Cai; Mingxiao Xie; Hongshuai Qi; Yigang Wang (Journal of Marine Science and Engineering, 2021)
Implementing shoreface nourishment is an effective method to protect sandy beaches. A better understanding of the equilibrium mechanism of shoreface nourishments is necessary for coastal engineering designs and constructions. Two experiments on the beach profile equilibrium of the shoreface nourishment are carried out under mild wave conditions on the reflective and intermediate beach. It is observed that the shoreface nourishment increases local wave height and strengthens wave nonlinearity by its shallow water depth. The most intense wave breaking dissipation has been found on the crest of the shoreface nourishment, and the distribution of wave energy dissipation rate is more uniform on the quasi-equilibrium profile than that on the initial profile. A process-based numerical model is used to reproduce bed profile evolution successfully. On that basis, it is found that onshore bedload transport is the primary cause for the onshore migration of the shoreface nourishment. The magnitude of bedload transport decreases during the evolution of the shoreface nourishment towards equilibrium. The most intense sediment transport rate occurs over the shoreface nourishment or in front of the shoreline, depending on the ’lee effect’ of the nourishment. Furthermore, the effects of incident wave height, wave period, and sea-level rise on the equilibrium profile of the shoreface nourishment under mild wave conditions are analyzed.

Quantum dot-labelled antibody based on fluorescence immunoassays for the determination of arsanilic acid in edible pork and liver - Aiping Wang; Jinge Li; Hongliang Liu; Yumei Chen; Jingming Zhou; Yankai Liu; Yanhua Qi; Wenjing Jiang; Gaiping Zhang (Food Additives & Contaminants: Part A, 2021)

Gut microbiome alterations and its link to corticosteroid resistance in immune thrombocytopenia - Yanan Wang; Fengqi Liu; Gaochao Zhang; Yan Su; Xueyan Sun; Qi Chen; Chencong Wang; Haixia Fu; Yun He; Xiaolu Zhu; Xiao Liu; Meng Lv; et al. (Science China Life Sciences, 2021)

Normal Faulting Movement During the 2020 Mw 6.4 Yutian Earthquake: A Shallow Rupture in NW Tibet Revealed by Geodetic Measurements - Jiansheng Yu; Dongzhen Wang; Bin Zhao; Qi Li (Pure and Applied Geophysics, 2021)

Neuromodulation-Based Stem Cell Therapy in Brain Repair: Recent Advances and Future Perspectives - Ti-Fei Yuan; Yi Dong; Li Zhang; Jieyu Qi; Chun Yao; Yongjun Wang; Renjie Chai; Yan Liu; Kwok-Fai So (Neuroscience Bulletin, 2021)

Experiments on granular flow behavior and deposit characteristics: implications for rock avalanche kinematics - Kun Li; Yu-Feng Wang; Qi-Wen Lin; Qian-Gong Cheng; Yue Wu (Landslides, 2021)

Construction of the first high-density genetic map for growth related QTL analysis in Ancherythroculter nigrocauda - Yanhong Sun; Pei Li; Guiying Wang; Renli Sun; Jian Chen; Qi Zhou; Jingou Tong; Qing Li (Journal of Oceanology and Limnology, 2021)

RET compound inheritance in Chinese patients with Hirschsprung disease: lack of penetrance from insufficient gene dysfunction - Qian Jiang; Yang Wang; Yang Gao; Hui Wang; Zhen Zhang; Qi Li; Shuhua Xu; Wei Cai; Long Li (Human Genetics, 2021)

Development and evaluation of a serological test for diagnosis of COVID-19 with selected recombinant spike proteins - Pingping Zhang; Qi Gao; Tang Wang; Yuehua Ke; Fei Mo; Ruizhong Jia; Wanbing Liu; Lei Liu; Shangen Zheng; Yuzhen Liu; Luping Li; Yao Wang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Recent progress in induced pluripotent stem cell-derived 3D cultures for cardiac regeneration - Kai-Li Wang; Qi Xue; Xun-Hong Xu; Fang Hu; Hong Shao (Cell and Tissue Research, 2021)

Genome sequencing and functional annotation of Bacillus sp. strain BS-Z15 isolated from cotton rhizosphere soil having antagonistic activity against Verticillium dahliae - Zhong-Yi Chen; Xieerwanimu Abuduaini; Nuramina Mamat; Qi-Lin Yang; Meng-Jun Wu; Xin-Rui Lin; Ru Wang; Rong-Rong Lin; Wei-Jun Zeng; Huan-Chen Ning; He-Ping Zhao; Jin-Yu Li; et al. (Archives of Microbiology, 2021)

An upper bound design method for roof bolting support in roadways with top coal - Hongtao Wang; Luyao Liu; Shucai Li; Qi Wang; Weiteng Li; Qingbin Meng (Arabian Journal of Geosciences, 2021)

Seasonal Variations in Total Lipid and Fatty Acid Composition of Haliotis discus Hannai from Three Different Production Zones - Lipin Chen; Qi Wang; Xiaohan Cong; Fanqianhui Yu; Yong Xue; Qingjuan Tang; Changhu Xue; Yanqing Liu; Zhaojie Li (Journal of Aquatic Food Product Technology, 2021)

Fine mapping QTL and mining genes for protein content in soybean by the combination of linkage and association analysis - Xiyu Li; Ping Wang; Kaixin Zhang; Shulin Liu; Zhongying Qi; Yanlong Fang; Yue Wang; Xiaocui Tian; Jie Song; Jiajing Wang; Chang Yang; Xu Sun; et al. (Theoretical and Applied Genetics, 2021)

The association between hand grip strenght and global PSQI score in the middleaged and elderly population - Jinlin Li; Qingping Zhang; Qi Wang; Lingli Zhou; Xin Wan; Xi Zeng (Sleep and Biological Rhythms, 2021)

Decoding Cortical Glial Cell Development - Xiaosu Li; Guoping Liu; Lin Yang; Zhenmeiyu Li; Zhuangzhi Zhang; Zhejun Xu; Yuqun Cai; Heng Du; Zihao Su; Ziwu Wang; Yangyang Duan; Haotian Chen; et al. (Neuroscience Bulletin, 2021)
Mouse cortical radial glial cells (RGCs) are primary neural stem cells that give rise to cortical oligodendrocytes, astrocytes, and olfactory bulb (OB) GABAergic interneurons in late embryogenesis. There are fundamental gaps in understanding how these diverse cell subtypes are generated. Here, by combining single-cell RNA-Seq with intersectional lineage analyses, we show that beginning at around E16.5, neocortical RGCs start to generate ASCL1 + EGFR + apical multipotent intermediate progenitors (MIPCs), which then differentiate into basal MIPCs that express ASCL1, EGFR, OLIG2, and MKI67. These basal MIPCs undergo several rounds of divisions to generate most of the cortical oligodendrocytes and astrocytes and a subpopulation of OB interneurons. Finally, single-cell ATAC-Seq supported our model for the genetic logic underlying the specification and differentiation of cortical glial cells and OB interneurons. Taken together, this work reveals the process of cortical radial glial cell lineage progression and the developmental origins of cortical astrocytes and oligodendrocytes.

A feedback loop: Interactions between Inflammatory Signals and Clonal Hematopoiesis in Cardiovascular Disease - Jiashan Li; Chao Wang; Jiaru Liu; Ying Yu; Yuee Liu; Qi Peng; Huihui Liu; Xiuru Guan (Molecular Biology Reports, 2021)

Transcriptomic analysis of saffron at different flowering stages using RNA sequencing uncovers cytochrome P450 genes involved in crocin biosynthesis - Guangchun Gao; Jiming Wu; Bai Li; Qi Jiang; Ping Wang; Jun Li (Molecular Biology Reports, 2021)

Maternal Separation-Induced Histone Acetylation Correlates with BDNF-Programmed Synaptic Changes in an Animal Model of PTSD with Sex Differences - Haoran Sun; Xianqiang Zhang; Yujia Kong; Luping Gou; Bo Lian; Yanyu Wang; Li Jiang; Qi Li; Hongwei Sun; Lin Sun (Molecular Neurobiology, 2021)

Simvastatin Enhances Muscle Regeneration Through Autophagic Defect-Mediated Inflammation and mTOR Activation in G93ASOD1 Mice - Yafei Wang; Lin Bai; Shuai Li; Ya Wen; Qi Liu; Rui Li; Yaling Liu (Molecular Neurobiology, 2021)

The Roles of Epinephelus coioides miR-122 in SGIV Infection and Replication - Hong-Yan Sun; Yu-Ling Su; Pin-Hong Li; Jia-Yang He; He-Jia Chen; Gang Wang; Shao-Wen Wang; Xiao-Hong Huang; You-Hua Huang; Qi-Wei Qin (Marine Biotechnology, 2021)
In mammals, mature miR-122 is 22 nucleotides long and can be involved in regulating a variety of physiological and biological pathways. In this study, the expression profile and effects of grouper Epinephelus coioides miR-122 response to Singapore grouper iridovirus (SGIV) infection were investigated. The sequences of mature microRNAs (miRNAs) from different organisms are highly conserved, and miR-122 from E. coioides exhibits high similarity to that from mammals and other fish. The expression of miR-122 was up-regulated during SGIV infection. Up-regulation of miR-122 could significantly enhance the cytopathic effects (CPE) induced by SGIV, the transcription levels of viral genes (MCP, VP19, LITAF and ICP18), and viral replication; reduce the expression of inflammatory factors (TNF-a, IL-6, and IL-8), and the activity of AP-1 and NF-κB, and miR-122 can bind the target gene p38α MAPK to regulate the SGIV-induced cell apoptosis and the protease activity of caspase-3. The results indicated that SGIV infection can up-regulate the expression of E. coioides miR-122, and up-regulation of miR-122 can affect the activation of inflammatory factors, the activity of AP-1 and NF-κB, and cell apoptosis to regulate viral replication and proliferation.

Microbiological profiles and antimicrobial resistance patterns of pediatric bloodstream pathogens in China, 2016–2018 - Yue Qiu; Junwen Yang; Yiping Chen; Jinhong Yang; Qingxiong Zhu; Chunhui Zhu; Shuangjie Li; Jing Liu; Chaomin Wan; Yu Zhu; Minxia Chen; Yi Xu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Clinical and microbiological characteristics of adults with hospital-acquired pneumonia: a 10-year prospective observational study in China - Yuyao Yin; Chunjiang Zhao; Henan Li; Longyang Jin; Qi Wang; Ruobing Wang; Yawei Zhang; Jiangang Zhang; Hui Wang; Chunxia Yang; Bin Cao; Yingmei Liu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Population-based meta-analysis of chloroquine: informing chloroquine pharmacokinetics in COVID-19 patients - Xueting Yao; Xiaoyu Yan; Xiaohan Wang; Ting Cai; Shun Zhang; Cheng Cui; Xiaoxu Wang; Zhe Hou; Qi Liu; Haiyan Li; Jing Lin; Zi Xiong; et al. (European Journal of Clinical Pharmacology, 2021)
Aims Chloroquine (CQ) has been repurposed to treat coronavirus disease 2019 (COVID-19). Understanding the pharmacokinetics (PK) in COVID-19 patients is essential to study its exposure–efficacy/safety relationship and provide a basis for a possible dosing regimen optimization. Subject and methods In this study, we used a population-based meta-analysis approach to develop a population PK model to characterize the CQ PK in COVID-19 patients. An open-label, single-center study (ethical review approval number: PJ-NBEY-KY-2020-063-01) was conducted to assess the safety, efficacy, and pharmacokinetics of CQ in patients with COVID-19. The sparse PK data from 50 COVID-19 patients, receiving 500 mg CQ phosphate twice daily for 7 days, were combined with additional CQ PK data from 18 publications. Results A two-compartment model with first-order oral absorption and first-order elimination and an absorption lag best described the data. Absorption rate (ka) was estimated to be 0.559 h −1 , and a lag time of absorption (ALAG) was estimated to be 0.149 h. Apparent clearance (CL/F) and apparent central volume of distribution (V2/F) was 33.3 l/h and 3630 l. Apparent distribution clearance (Q/F) and volume of distribution of peripheral compartment (Q3/F) were 58.7 l/h and 5120 l. The simulated CQ concentration under five dosing regimens of CQ phosphate were within the safety margin (400 ng/ml). Conclusion Model-based simulation using PK parameters from the COVID-19 patients shows that the concentrations under the currently recommended dosing regimen are below the safety margin for side-effects, which suggests that these dosing regimens are generally safe. The derived population PK model should allow for the assessment of pharmacokinetics–pharmacodynamics (PK-PD) relationships for CQ when given alone or in combination with other agents to treat COVID-19.

Correction to: Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Bai; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Ba; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Promoter engineering for high ectoine production in a lower saline medium by Halomonas hydrothermalis Y2 - Shannan Li; Yan Shang; Qi Zhao; Yuanxiang Liu; Xueqian Dong; Wenkai Wang; Chunyu Yang (Biotechnology Letters, 2021)

Association Between Blood Heavy Metal Concentrations and Dyslipidemia in the Elderly - Xingmeng Zhu; Yong Fan; Jie Sheng; Ling Gu; Qi Tao; Rui Huang; Kaiyong Liu; Linsheng Yang; Guimei Chen; Hongjuan Cao; Kaichun Li; Fangbiao Tao; et al. (Biological Trace Element Research, 2021)

Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71 - Ya-Ping Li; Mu-Qi Wang; Chen-Rui Liu; Hui-Ling Deng; Yuan Wu; Shuang-Suo Dang; Li-Hong Xu (Archives of Virology, 2021)

Cold-induced Yes-associated-protein expression through miR-429 mediates the browning of white adipose tissue - Chenji Ye; Jinjie Duan; Xuejiao Zhang; Liu Yao; Yayue Song; Guangyan Wang; Qi Li; Biqing Wang; Ding Ai; Chunjiong Wang; Yi Zhu (Science China Life Sciences, 2021)

Transcriptome sequencing and analysis for the pigmentation of scale and skin in common carp (Cyprinus carpio) - Yu-Jie Zhao; Jun Xiao; Mei-Di Huangyang; Ran Zhao; Qi Wang; Yan Zhang; Jiong-Tang Li (Molecular Biology Reports, 2021)

EphA1 Activation Induces Neuropathological Changes in a Mouse Model of Parkinson’s Disease Through the CXCL12/CXCR4 Signaling Pathway - Jianjun Ma; Zhidong Wang; Siyuan Chen; Wenhua Sun; Qi Gu; Dongsheng Li; Jinhua Zheng; Hongqi Yang; Xue Li (Molecular Neurobiology, 2021)

Simulation of the fragmentation and propagation of jointed rock masses in rockslides: DEM modeling and physical experimental verification - Qi-wen Lin; Qian-Gong Cheng; Yu Xie; Feng-shou Zhang; Kun Li; Yu-feng Wang; Yuan-yuan Zhou (Landslides, 2021)

Impact of densely distributed debris flow dams on river morphology of the Grand Canyon of the Nu River (upper Salween River) at the east margin of the Tibetan Plateau - Liqun Lyu; Mengzhen Xu; Zhaoyin Wang; Lijian Qi; Xin Li (Landslides, 2021)

Spatial distribution and ecological assessment of nickel in sediments of a typical small plateau lake from Yunnan Province, China - Bo Li; Hang Wang; Qingguo Yu; Feng Wei; Qi Zhang (Environmental Science and Pollution Research, 2021)

Enhanced antioxidant capacity and upregulated transporter genes contribute to the UV-B-induced increase in blinin in Conyza blinii - Junyi Zhan; Qin Yang; Zhiyi Lin; Tianrun Zheng; Maojia Wang; Wenjun Sun; Tongliang Bu; Zizhong Tang; Chenglei Li; Xueyi Han; Haixia Zhao; Qi Wu; et al. (Environmental Science and Pollution Research, 2021)

Determination of nonlinear seepage slope for dislocation interface by in situ tests - Zhifang Zhou; Zhe Wang; Sijia Li; Qi Shen; Meng Chen; Hu Zheng (Bulletin of Engineering Geology and the Environment, 2021)

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

Suppression of miR-4463 promotes phenotypic switching in VSMCs treated with Ox-LDL - Xueqin Wang; Hui Li; Yuetian Zhang; Qi Liu; Xiaolei Sun; Xuemei He; Qian Yang; Ping Yuan; Xiangyu Zhou (Cell and Tissue Research, 2021)

A novel alginate localization molding technique for cross-sectional area measurement of human tendon to access biomechanical properties - Xiaojing Ge; Jinju Ding; Minghui Wang; Qi Li; Yongcheng Hu; Dengxing Lun; Lei Zhang; Limin Wang; Wenru Wang; Bin Liu (Cell and Tissue Banking, 2021)

Least-squares reverse time migration method using the factorization of the Hessian matrix - Sun Xiao-Dong; Teng Hou-Hua; Ren Li-Juan; Wang Wei-Qi; Li Zhen-Chun (Applied Geophysics, 2021)

A single nucleotide polymorphism variant located in the cis ‐regulatory region of the ABCG2 gene is associated with mallard egg colour - Hehe Liu; Jian Hu; Zhanbao Guo; Wenlei Fan; Yaxi Xu; Suyun Liang; Dapeng Liu; Yunsheng Zhang; Ming Xie; Jing Tang; Wei Huang; Qi Zhang; et al. (Molecular Ecology, 2021)
Avian egg coloration is shaped by natural selection, but its genetic basis remains unclear. Here, we used genome‐wide association analysis and identity by descent to finely map green egg colour to a 179‐kb region of Chr4 based on the resequencing of 352 ducks ( Anas platyrhynchos ) from a segregating population resulting from the mating of Pekin ducks (white‐shelled eggs) and mallards (green‐shelled eggs). We further narrowed the candidate region to a 30‐kb interval by comparing genome divergence in seven indigenous duck populations. Among the genes located in the finely mapped region, only one transcript of the ABCG2 gene (XM_013093252.2) exhibited higher uterine expression in green‐shelled individuals than in white‐shelled individuals, as supported by transcriptome data from four populations. ABCG2 has been reported to encode a protein that functions as a membrane transporter for biliverdin. Sanger sequencing of the whole 30‐kb candidate region (Chr4: 47.41–47.44 Mb) and a plasmid reporter assay helped to identify a single nucleotide polymorphism (Chr4: 47,418,074 G>A) located in a conserved predicted promoter region whose variation may alter ABCG2 transcription activity. We provide a useful molecular marker for duck breeding and contribute data to the research on ecological evolution based on egg colour patterns among birds.

Network pharmacology uncovers anti-cancer activity of vibsane-type diterpenes from Viburnum odoratissimum - Ying-Ying Zhang; Jing-Jie Chen; Dan-Qi Li; Yan- Zhang; Xiao-Bo Wang; Guo-Dong Yao; Shao-Jiang Song (Natural Product Research, 2021)

Transcriptional and post-transcriptional regulation of the miR171-LaSCL6 module during somatic embryogenesis in Larix kaempferi - Qiao-Lu Zang; Yao Zhang; Su-Ying Han; Wan-Feng Li; Li-Wang Qi (Trees, 2021)
Key message Expression analysis of Larix kaempferi mature miR171s and their primary transcripts and target gene LaSCL6 during somatic embryogenesis revealed the transcriptional and post-transcriptional regulation of the miR171- LaSCL6 module. Abstract Somatic embryogenesis provides a useful experimental system for studying the regulatory mechanisms of plant development. The level and activity of microRNA171 (miR171) fluctuate during somatic embryogenesis in Larix kaempferi , but the underlying mechanisms are still unclear. Here, in L. kaempferi we identified five members of the miR171 family, which cleave LaSCL6 mRNA at different sites. In addition, we improved the method of measuring miRNA activity in a more direct way. Furthermore, we measured the expression patterns of mature miR171s and their primary transcripts during somatic embryogenesis in L. kaempferi and found that their patterns differed, indicating that the transcription of MIR171 genes and the subsequent cleavage of their intermediate products are regulated. Taken together, our findings not only offer a means to study the regulation of miRNA activity, but also provide further insight into the regulation of L . kaempferi somatic embryogenesis by miR171- LaSCL6 .

Modulation of evening complex activity enables north-to-south adaptation of soybean - Xiaolong Fang; Yapeng Han; Mengshi Liu; Jiacan Jiang; Xiang Li; Qichao Lian; Xianrong Xie; Yian Huang; Qibin Ma; Hai Nian; Ji Qi; Cunyi Yang; et al. (Science China Life Sciences, 2021)

Evaluation and application of an efficient plant DNA extraction protocol for laboratory and field testing - Qi Wang; Xiaoxia Shen; Tian Qiu; Wei Wu; Lin Li; Zhi’an Wang; Huixia Shou (Journal of Zhejiang University-SCIENCE B, 2021)

Identification of Pythium species as pathogens of garlic root rot - Bo Zhang; Yueli Zhang; Liguo Ma; Kai Qi; Peng Wang; Changsong Li; Junshan Qi (Journal of Plant Pathology, 2021)

Preliminary report on the improved resistance towards Pseudomonas syringae pv. actinidiae of cultivated kiwifruit (Actinidia chinensis) when grafted onto wild Actinidia guilinensis rootstock in vitro - Fa-ming Wang; Jie-wei Li; Kai-yu Ye; Hong-juan Gong; Ping-ping Liu; Qiao-sheng Jiang; Bei-bei Qi; Quan-hui Mo (Journal of Plant Pathology, 2021)

Regulation of peroxisome proliferator-activated receptor-gamma activity affects the hepatic stellate cell activation and the progression of NASH via TGF-β1/Smad signaling pathway - Xi-Xi Ni; Xiao-Yun Li; Qi Wang; Jing Hua (Journal of Physiology and Biochemistry, 2021)

Role of solution chemistry in the attachment of graphene oxide nanoparticles onto iron oxide minerals with different characteristics - Ruixia Jin; Taotao Lu; Haojing Zhang; Mengjie Wang; Mengli Wang; Wei Qi; Zhichong Qi; Deliang Li (Environmental Science and Pollution Research, 2021)

Spatial variation in macrobenthic assemblages and their relationship with environmental factors in the upstream and midstream regions of the Heihe River Basin, China - Yu Wang; Juan-Juan Liu; Wei Liu; Qi Feng; Bao-long Li; Han Lu; Shuang Wang (Environmental Monitoring and Assessment, 2021)
The Heihe River is a typical inland river under increasing anthropogenic pressure. To explore the characteristics of the macrobenthic assemblages and their relationships with environmental factors in the upstream and midstream regions of this basin, abiotic conditions and macrobenthic assemblages were investigated in the summers of 2018 and 2019. A total of 50 species were collected, and Arthropoda and mollusks were the dominant groups. A significant increase in standing stock was observed from the upstream to midstream, and predators (PR) were the main functional feeding group. A one-way analysis of variance (ANOVA) revealed that the Shannon-Wiener index and Margalef’s index values significantly differed at the spatial scale ( P < 0.05). A redundancy analysis (RDA) and Pearson correlation analysis showed that the spatial heterogeneity of the macrobenthos was influenced by the biochemical oxygen demand (BOD 5 ), water temperature (WT), total nitrogen (TN), salinity, electrical conductivity (EC), total dissolved solids (TDS), dissolved oxygen (DO), and potassium permanganate index (COD Mn ) ( P < 0.05). The spatial variation of macrobenthos was mainly governed by natural conditions and human disturbances.

Molecular evolution and pathogenicity of chicken anemia virus isolates in China - Yue Li; Nana Yan; Yongqiang Wang; Aijing Liu; Changjun Liu; Xingge Lan; Bo Yang; Yulong Gao; Honglei Gao; Xiaole Qi; Hongyu Cui; Kai Li; et al. (Archives of Virology, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Indole alkaloid glycosides from Isatis tinctoria roots - Dongdong Zhang; Kang Du; Yitian Zhao; Songshan Shi; Yingchun Wu; Qi Jia; Kaixian Chen; Yiming Li; Rui Wang (Natural Product Research, 2021)

Diet drives convergent evolution of gut microbiomes in bamboo-eating species - Guangping Huang; Xiao Wang; Yibo Hu; Qi Wu; Yonggang Nie; Jiuhong Dong; Yun Ding; Li Yan; Fuwen Wei (Science China Life Sciences, 2021)

Astrocyte-Derived Lactate Modulates the Passive Coping Response to Behavioral Challenge in Male Mice - Ya-Nan Yin; Jian Hu; Yi-Li Wei; Ze-Lin Li; Zhou-Cai Luo; Rui-Qi Wang; Ke-Xin Yang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Biological roles of the B cell receptor-associated protein 31: Functional Implication in Cancer - Mwichie Namusamba; Zhi Li; Qi Zhang; Changli Wang; Tianyi Wang; Bing Wang (Molecular Biology Reports, 2021)

Impact of air pollution exposure during various periods of pregnancy on term birth weight: a large-sample, retrospective population-based cohort study - Li Shang; Liyan Huang; Liren Yang; Longtao Leng; Cuifang Qi; Guilan Xie; Ruiqi Wang; Leqian Guo; Wenfang Yang; Mei Chun Chung (Environmental Science and Pollution Research, 2021)
Previous studies have suggested that maternal exposure to air pollution might affect term birth weight. However, the conclusions are controversial. Birth data of all term newborns born in Xi’an city of Shaanxi, China, from 2015 to 2018 and whose mother lived in Xi’an during pregnancy were selected form the Birth Registry Database. And the daily air quality data of Xi’an city was collected from Chinese Air Quality Online Monitoring and Analysis Platform. Generalized additive models (GAM) and 2-level binary logistic regression models were used to estimate the effects of air pollution exposure on term birth weight, the risk term low birth weight (TLBW), and macrosomia. Finally, 321521 term newborns were selected, including 4369(1.36%) TLBW infants and 24,960 (7.76%) macrosomia. The average pollution levels of PM 2.5 , PM 10 , and NO 2 in Xi’an city from 2015 to 2018 were higher than national limits. During the whole pregnancy, maternal exposure to PM 2.5 , PM 10 , SO 2 , and CO all significantly reduced the term birth weight and increased the risk of TLBW. However, NO 2 and O 3 exposure have significantly increased the term birth weight, and O 3 even increased the risk of macrosomia significantly. Those effects were also observed in the first and second trimesters of pregnancy. But during the third trimester, high level of air quality index (AQI) and maternal exposure to PM 2.5 , PM 10 , SO 2 , NO 2 , and CO increased the term birth weight and the risk of macrosomia, while O 3 exposure was contrary to this effect. The findings suggested that prenatal exposure to air pollution might cause adverse impacts on term birth weight, and the effects varied with trimesters and pollutants, which provides further pieces of evidence for the adverse effects of air pollution exposure in heavy polluted-area on term birth weight.

Hydrothermal dolomitization in the Middle Permian in the Central Sichuan Basin, SW China: evidence from petrology, geochemistry, and fluid inclusions - Lin Qi; Yifan Gu; Puwei He; Zhanlei Wang; Yuqiang Jiang; Shun Li; Yadong Zhou (Arabian Journal of Geosciences, 2021)

Phylogeny of Veneridae (Bivalvia) based on mitochondrial genomes - Yu Wang; Yi Yang; Hongyue Liu; Lingfeng Kong; Hong Yu; Shikai Liu; Qi Li (Zoologica Scripta, 2021)
Veneridae is one of the most diverse families of bivalve molluscs. However, their phylogenetic relationships among subfamilies have been debated for years. To explore phylogenetic relationships of Veneridae, we sequenced 13 complete mitochondrial genome sequences from eight subfamilies and compared with available complete mitochondrial genome of other Veneridae taxa (18 previously reported sequences). Phylogenetic analyses using probabilistic methods recovered two highly supported clades. In addition, the protein‐coding gene order revealed a highly conserved pattern among the same subclade lineages. According to our molecular analyses, Tapetinae should be recognized as a valid subfamily, but the genera formed para‐polyphyletic clades. Chioninae was recovered not monophyletic that differs from a previously molecular phylogeny. Furthermore, the reconstructed chronogram calibrated with fossils recovered the Veneridae have originated during the early Permian (about 290 million years ago). Noticeably, programmed frameshift was found in the nad4 gene of Leukoma jedoensis , Anomalodiscus squamosus and Antigona lamellaris and cob gene of L. jedoensis . This is the first time that the presence of the programmed frameshift has been found in the protein‐coding genes of Heterodonta species. Our results improved the phylogenetic resolution within Veneridae, and a more taxonomic sampling analysis of the subfamily Chioninae is supposed to construct.

A novel, validated, and plant height-independent QTL for spike extension length is associated with yield-related traits in wheat - Cong Li; Huaping Tang; Wei Luo; Xuemei Zhang; Yang Mu; Mei Deng; Yaxi Liu; Qiantao Jiang; Guoyue Chen; Jirui Wang; Pengfei Qi; Zhien Pu; et al. (Theoretical and Applied Genetics, 2020)

Adakitic rocks at convergent plate boundaries: Compositions and petrogenesis - Qiang Wang; Lulu Hao; Xiuzheng Zhang; Jinsheng Zhou; Jun Wang; Qiwei Li; Lin Ma; Long Zhang; Yue Qi; Gongjian Tang; Wei Dan; Jingjing Fan (Science China Earth Sciences, 2020)

The origin of arc basalts: New advances and remaining questions - Yigang Xu; Qiang Wang; Gongjian Tang; Jun Wang; Hongyan Li; Jinsheng Zhou; Qiwei Li; Yue Qi; Pingping Liu; Lin Ma; Jingjing Fan (Science China Earth Sciences, 2020)

Magnesium decreases aluminum accumulation and plays a role in protecting maize from aluminum-induced oxidative stress - Xiangying Kong; Zhongping Peng; Dongxu Li; Wenna Ma; Ruidong An; Dawood Khan; Xinxun Wang; Yuan Liu; En Yang; Yuzhi He; Liqngquan Wu; Baige Zhang; et al. (Plant and Soil, 2020)

Correction to: Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Chang-Qi Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Anxiolytic Effects of 8-O-Acetyl Shanzhiside Methylester on Acute and Chronic Anxiety via Inflammatory Response Inhibition and Excitatory/Inhibitory Transmission Imbalance - Ting Sun; Li Luo; Qin-Qin Tian; Wen-Ju Wang; Qing-Qing Liu; Le Yang; Kun Zhang; Wei Zhang; Ming-Gao Zhao; Qi Yang (Neurotoxicity Research, 2020)
Anxiety leads to a global decline in quality of life and increase in social burden. However, treatments are limited, because the molecular mechanisms underlying complex emotional disorders are poorly understood. We explored the anxiolytic effects of 8-O-acetyl shanzhiside methylester (8-OaS), an active component in Lamiophlomis rotata ( L . rotata ; Benth.) or Kudo, a traditional herb that has been shown to be effective in the clinical treatment of chronic pain syndromes in China. Two mouse anxiety models were used: forced swimming stress (FSS)–induced anxiety and complete Freund’s adjuvant (CFA)–induced chronic inflammatory pain. All animal behaviors were analyzed on the elevated plus maze and in the open-field test. 8-OaS significantly ameliorated anxiety-like behaviors in both anxiety models and inhibited the translation enhancement of GluN2A, GluN2B, and PSD95. Moreover, a reduction in GABA receptors disrupted the excitatory/inhibitory (E/I) balance in the basolateral amygdala (BLA), indicated by increased excitatory and decreased inhibitory presynaptic release. 8-OaS also blocked microglia activation and reduced the phosphorylation of p38, c-Jun N-terminal kinase (JNK), NF-κB p65, and tumor necrosis factor alpha (TNF-α) in the BLA of anxiety mice. 8-OaS exhibits obvious anxiolytic effects by regulating the excitatory/inhibitory (E/I) synaptic transmission and attenuating inflammatory responses in the BLA.

Connexin 36 Mediates Orofacial Pain Hypersensitivity Through GluK2 and TRPA1 - Qian Li; Tian-Le Ma; You-Qi Qiu; Wen-Qiang Cui; Teng Chen; Wen-Wen Zhang; Jing Wang; Qi-Liang Mao-Ying; Wen-Li Mi; Yan-Qing Wang; Yu-Xia Chu (Neuroscience Bulletin, 2020)

Factors associated with a SARS-CoV-2 recurrence after hospital discharge among patients with COVID-19: systematic review and meta-analysis - Meng-qi Yao; Qiu-xian Zheng; Jia Xu; Jing-wen Deng; Tian-tian Ge; Hai-bo Zhou; Feng-tian Wu; Xin-yu Gu; Qin Yang; Yan-li Ren; Gang Wang; Zhi Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model - Xuan Zhou; Jia-qi Li; Li-jie Wei; Meng-zhou He; Jing Jia; Jing-yi Zhang; Shao-shuai Wang; Ling Feng (Journal of Zhejiang University-SCIENCE B, 2020)

The extract of aquatic macrophyte Carex cinerascens induced colony formation in bloom-forming cyanobacterium Microcystis aeruginosa - Lin Li; Xiao-ling Jing; Ling Wang; Zhi-gao Zeng; Wen-hong Chen; Jia-hao Zhai; Si-qin Qi (Environmental Science and Pollution Research, 2020)

Ferruginous microbialite blooms of the Miaolingian (Cambrian) in the southern North China Craton: a response to the volcanic event? - Xiyang Zhang; Yong’an Qi; Yue Li; Mingyue Dai; Min Wang (Carbonates and Evaporites, 2020)

Patterns of intrinsic brain activity in essential tremor with resting tremor and tremor-dominant Parkinson’s disease - Jun-ying Li; Zhong-jiao Lu; Xue-ling Suo; Nan-nan Li; Du Lei; Ling Wang; Jia-xin Peng; Li-ren Duan; Jing Xi; Yi Jiang; Qi-yong Gong; Rong Peng (Brain Imaging and Behavior, 2020)

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

Fundamental Characteristics of Tropical Rain Cell Structures as Measured by TRMM PR - Yunfei Fu; Yilun Chen; Xiangdong Zhang; Yu Wang; Rui Li; Qi Liu; Lei Zhong; Qiong Zhang; Aoqi Zhang (Journal of Meteorological Research, 2020)

LncRNA A2M-AS1 lessens the injury of cardiomyocytes caused by hypoxia and reoxygenation via regulating IL1R2 - Xue-Lian Song; Fei-Fei Zhang; Wen-Jing Wang; Xin-Ning Li; Yi Dang; Ying-Xiao Li; Qian Yang; Mei-Jing Shi; Xiao-Yong Qi (Genes & Genomics, 2020)

Characterization and genome analysis of Klebsiella phage P509, with lytic activity against clinical carbapenem-resistant Klebsiella pneumoniae of the KL64 capsular type - Min Li; Yuyi Xiao; Pei Li; Zitong Wang; Weiling Qi; Zitai Qi; Liang Chen; Hong Du; Wei Zhang (Archives of Virology, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions - Xiuxiu Li; Zhuo Chen; Guomin Zhang; Hongwei Lu; Peng Qin; Ming Qi; Ying Yu; Bingke Jiao; Xianfeng Zhao; Qiang Gao; Hao Wang; Yunyu Wu; et al. (Science China Life Sciences, 2020)

Identification and Characterization of the Nuclease Activity of the Extracellular Proteins from Salmonella enterica Serovar Typhimurium - Chengshui Liao; Mengke Zhang; Xiangchao Cheng; Qi Li; Fuchao Mao; Xiaoli Wang; Chuan Yu; Zuhua Yu; Yanyan Jia; Jing Li; Lei He; Chunjie Zhang; et al. (Current Microbiology, 2020)

Slope failure of biotreated sand embankments under rainfall conditions: experimental investigation and numerical simulation - Zhaoyu Wang; Qi Li; Nan Zhang; Yong Jin; Haibo Qin; Jinhua Ding (Bulletin of Engineering Geology and the Environment, 2020)

Food-grade expression of nattokinase in Lactobacillus delbrueckii subsp. bulgaricus and its thrombolytic activity in vitro - Chen Li; Zaihui Du; Shaoqing Qi; Xin Zhang; Miaoshu Wang; Yangping Zhou; Haiqiang Lu; Xinxi Gu; Hongtao Tian (Biotechnology Letters, 2020)

RETRACTED ARTICLE: Detrimental Effects of Sodium Fluoride on the Expression of Insulin Receptor in the Olfactory Bulb and Hippocampus of Male Mice - Jianqin Yuan; Qi Li; Mohammad Mehdi Ommati; Ruiyan Niu; Jundong Wang (Biological Trace Element Research, 2020)

Nitrification inhibitor DMPP offsets the increase in N2O emission induced by soil salinity - Yawei Li; Junzeng Xu; Xiaoyin Liu; Zhiming Qi; Haiyu Wang; Youjia Li; Linxian Liao (Biology and Fertility of Soils, 2020)

Glycyrrhizin Prevents Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke with Delayed Thrombolysis Through Targeting Peroxynitrite-Mediated HMGB1 Signaling - Hansen Chen; Binghe Guan; Bin Wang; Haiwei Pu; Xiaoyu Bai; Xi Chen; Jihong Liu; Caiming Li; Jinhua Qiu; Dan Yang; Kejian Liu; Qi Wang; et al. (Translational Stroke Research, 2020)

An Experimental Study of Effect of High Temperature on the Permeability Evolution and Failure Response of Granite Under Triaxial Compression - Sheng-Qi Yang; Wen-Ling Tian; Derek Elsworth; Jian-Guo Wang; Li-Feng Fan (Rock Mechanics and Rock Engineering, 2020)

Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice - Qi Yang; Li Luo; Ting Sun; Le Yang; Li-Fei Cheng; Yan Wang; Qing-Qing Liu; An Liu; Hai-Yan Liu; Ming-Gao Zhao; Sheng-Xi Wu; Bin Feng (Psychopharmacology, 2020)

FtMYB18 acts as a negative regulator of anthocyanin/proanthocyanidin biosynthesis in Tartary buckwheat - Qixin Dong; Haixia Zhao; Yunji Huang; Ying Chen; Min Wan; Zixian Zeng; Panfeng Yao; Chenglei Li; Xiaoli Wang; Hui Chen; Qi Wu (Plant Molecular Biology, 2020)

Phaeotremella camelliae sp. nov. (Phaeotremellaceae, Tremellales), A Novel Yeasts Isolated from Tea-Oil Fruits in Jiangxi Province, China - Yong Sun; Gui-Shuang Wang; Ai-Hua Li; Wangmu; Xian-Qiu Chui; Ji-Hong Jiang; Qi-Ming Wang (Current Microbiology, 2020)

Piperine inhibits colorectal cancer migration and invasion by regulating STAT3/Snail-mediated epithelial–mesenchymal transition - Lingyu Song; Yan Wang; Yunhuan Zhen; Dengke Li; Xidong He; Hong Yang; Huayang Zhang; Qi Liu (Biotechnology Letters, 2020)

The immune response to a recombinant Lactococcus lactis oral vaccine against foot-and-mouth disease virus in mice - Xinsheng Liu; Linlin Qi; Jianliang Lv; Zhongwang Zhang; Peng Zhou; Zhongyuan Ma; Yonglu Wang; Yongguang Zhang; Li Pan (Biotechnology Letters, 2020)

Internally controlled recombinase-aided amplification (IC-RAA) assays for the detection of human papillomavirus genotypes 16 and 18 using extracted DNA and samples treated with nucleic acid releasing agent - Jinrong Wang; Jianli Liu; Guowei Song; Zhi Cao; Jing Pan; Xinna Li; Yuan Gao; Juju Qi; Ziwei Chen; Guohao Fan; Xueding Bai; Ruiqing Zhang; et al. (Archives of Virology, 2020)

Correction to: A potent protective effect of baicalein on liver injury by regulating mitochondria-related apoptosis - Zhongjie Yu; Qi Li; Yin Wang; Peifeng Li (Apoptosis, 2020)

A new ocotillol-type ginsenoside from stems and leaves of Panax quinquefolium L. and its anti-oxidative effect on hydrogen peroxide exposed A549 cells - Zeng Qi; Zhenzhou Wang; Baisong Zhou; Shuilian Fu; Tie Hong; Pingya Li; Jinping Liu (Natural Product Research, 2020)

A novel sensitive electrochemical method for the detection of ractopamine in meat food via polycitrulline-modified electrode - Xinying Ma; Huiping Lv; Qi Zhu; Meifeng Chen; Yilei Wang; Fenghai Li (Food Additives & Contaminants: Part A, 2020)

Motion correction and noise removing in lung diffusion-weighted MRI using low-rank decomposition - Xinhui Wang; Houjin Chen; Qi Wan; Yanfeng Li; Naxin Cai; Xinchun Li; Yahui Peng (Medical & Biological Engineering & Computing, 2020)

Heroin Abuse and/or HIV Infection Dysregulate Plasma Exosomal miRNAs - Xu Wang; Li Sun; Yu Zhou; Qi-Jian Su; Jie-Liang Li; Li Ye; Man-Qing Liu; Wang Zhou; Wen-Zhe Ho (Journal of Neuroimmune Pharmacology, 2020)

Geochronology and sedimentology of the Huashan Group in the northern Yangtze Block: implications for the initial breakup of the South China - Kuizhou Li; Qi Deng; Mingcai Hou; Jian Wang; Chris Yakymchuk; Xiaozhuang Cui; Guangming Ren; Zhengjiang Wang (International Journal of Earth Sciences, 2020)

Age-dependent association of CYP2C19 polymorphisms with clinical outcome of clopidogrel therapy in minor stroke patients with large-artery atherosclerosis - Dapeng Wang; Lingjie Li; Jianhua Jiang; Quanquan Zhang; Meirong Liu; Yang Liu; Hongru Zhao; Qi Fang (European Journal of Clinical Pharmacology, 2020)

Transfer of the ph1b gene of ‘Chinese Spring’ into a common wheat cultivar with excellent traits - Y. Li; Q. Li; Y. Li; J. Lan; H. Tang; P. Qi; J. Ma; J. Wang; G. Chen; Z. Pu; W. Li; Z. Li; et al. (Cereal Research Communications, 2020)

Changes in leaf vein traits among vein types of alpine grassland plants on the Tibetan Plateau - Chang-shun Wang; Wang-wang Lyu; Li-li Jiang; Shi-ping Wang; Qi Wang; Fan-dong Meng; Li-rong Zhang (Journal of Mountain Science, 2020)