Fabrication of wide-spectra-responsive NA/NH2-MIL-125(Ti) with boosted activity for Cr(VI) reduction and antibacterial effects - Yangjie Fu; Meng Tan; Zhonglu Guo; Derek Hao; Youran Xu; Hao Du; Chao Zhang; Jiayun Guo; Qiang Li; Qi Wang (Chemical Engineering Journal, 2023)

Formation mechanism and metabolic pathways of photogranule in batch and continuous-flow mode under high salinity stress - Jing Zhu; Hong You; Zhipeng Li; Binghan Xie; Weirun Li; Shaojie Qi; Rui Wang; Hongying Chen; Binyu Ma; Yi Ding; Haili Tan; Feng Liu; et al. (Chemical Engineering Journal, 2023)

Recent progress of hollow structure platform in assisting oxygen evolution reaction - Qiaoli Li; Fengmin Sun; Di Zhang; Huilan Sun; Qiujun Wang; Jian Qi; Huan Wang; Zhaojin Li; Zhilin Hu; Bo Wang (Chemical Engineering Journal, 2023)

One-step fabrication of self-healing poly(thioctic acid) coatings on ZE21B Mg alloys for enhancing corrosion resistance, anti-bacterial/oxidation, hemocompatibility and promoting re-endothelialization - Zhao-Qi Zhang; Pei-Duo Tong; Li Wang; Zheng-Hui Qiu; Jing-An Li; Hang Li; Shao-Kang Guan; Cun-Guo Lin; Hong-Yan Wang (Chemical Engineering Journal, 2023)

Nature-inspired 3D hierarchical structured “vine” for efficient microwave attenuation and electromagnetic energy conversion device - Qiangqiang Wang; Ben Niu; Yuhang Han; Qi Zheng; Lin Li; Maosheng Cao (Chemical Engineering Journal, 2023)

Cationic molecular probes based on aggregation-induced emission for fluorescent sensing and super-resolution imaging of insulin fibrosis - Li-Jun Mei; Cheng Fan; Chu-Ran Xu; Qi Yu; Chong Li; Ya-Long Wang; Ming-Qiang Zhu (Chemical Engineering Journal, 2023)

Salt Bridge-intermediated three phase decoupling electrolytes for high voltage electrolytic aqueous Zinc-Manganese dioxides battery - Qi Xu; Qi-Xing Xie; Tong Xue; Gao Cheng; Jian-Dong Wu; Lan Ning; Xiang-Hui Yan; You-Jun Lu; Zhong-Li Zou; Bei-Ping Wang; Feng-Lan Han (Chemical Engineering Journal, 2023)

Ferrocene-boosting Zr-MOFs for efficient photocatalytic CO2 reduction: A trade-off between enhancing LMCT and frustrating Lewis acid - Li Xia; Wenxi Zhou; Yifan Xu; Zhengqiang Xia; Xinzhi Wang; Qi Yang; Gang Xie; Sanping Chen; Shengli Gao (Chemical Engineering Journal, 2023)

Polyamide microplastics act as carriers for cephalexin in the anammox process - Ye Wang; Dong-Qi Huang; Jun-Hui Yang; Gui-Feng Li; Ye-Xing Zhou; Jia-Yi Zhang; Ya Lu; Nian-Si Fan; Ren-Cun Jin (Chemical Engineering Journal, 2023)

A novel partially carbonized Fe3O4@PANI-p catalyst for tetracycline degradation via peroxymonosulfate activation - Ya-qi Wang; Kun Li; Mao-yuan Shang; Yi-zhen Zhang; Yang Zhang; Bo-lai Li; Yu-jiao Kan; Xiao-qiang Cao; Jian Zhang (Chemical Engineering Journal, 2023)

Mixed-linkage (1,3;1,4)-β-d-glucans as rehydration media for improved redispersion of dried cellulose nanofibrils - Li Zha; Shennan Wang; Lars A. Berglund; Qi Zhou (Carbohydrate Polymers, 2023)

Corrigendum to “CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage” [Carbohydrate Polymers 193 (2018) 268–280] - Jing-Bo Hu; Shu-Juan Li; Xu-Qi Kang; Jing Qi; Jia-Hui Wu; Xiao-Juan Wang; Xiao-Ling Xu; Xiao-Ying Ying; Sai-Ping Jiang; Jian You; Yong-Zhong Du (Carbohydrate Polymers, 2023)

Iron-blocking antibacterial therapy with cationic heme-mimetic gallium porphyrin photosensitizer for combating antibiotic resistance and enhancing photodynamic antibacterial activity - Hao Zhang; Qingsi Li; Xiaoyu Qi; Yi Li; Hongyan Ma; Mariusz Grinholc; Joanna Nakonieczna; Bingran Yu; Xing Wang; Lei Zhang (Chemical Engineering Journal, 2023)

The driving factors and buffering mechanism regulating cropland soil acidification across the Sichuan Basin of China - Aiwen Li; Chengji Li; Yuanyuan Zhang; Qian Deng; Hongyan Fang; Bin Zhao; Min Ran; Liangying Song; Jingling Xue; Qi Tao; Rong Huang; Yiding Li; et al. (CATENA, 2023)

High small ice concentration in stratiform clouds over Eastern China based on aircraft observations: Habit properties and potential roles of secondary ice production - Yang Wang; Ranyao Kong; Miao Cai; Yuquan Zhou; Can Song; Siyao Liu; Qi Li; Haoliang Chen; Chuanfeng Zhao (Atmospheric Research, 2023)

Estimation of hourly actual evapotranspiration over the Tibetan Plateau from multi-source data - Xian Wang; Lei Zhong; Yaoming Ma; Yunfei Fu; Cunbo Han; Peizhen Li; Zixin Wang; Yuting Qi (Atmospheric Research, 2023)

An inhibitory effect of schisandrone on α-hemolysin expression to combat methicillin-resistant staphylococcus aureus infections - Yingxin Qi; Juan Hou; Yicheng Zhao; Wu Song; Li Wang; Huan Chen; Guang Chen (World Journal of Microbiology and Biotechnology, 2023)

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in breast cancer that can be reversed by PI3K/mTOR inhibitors - Zijie Cai; Jingru Wang; Yudong Li; Qianfeng Shi; Liang Jin; Shunying Li; Mengdi Zhu; Qi Wang; Lok Lam Wong; Wang Yang; Hongna Lai; Chang Gong; et al. (Science China Life Sciences, 2023)

Shading reduced the compensation and enhancement effects of soil nutrition on the growth of cotyledon-damaged Quercus acutissima seedlings - Haonan Chen; Mingming Zhao; Luyu Qi; Xinke Sun; Qiang Li; Xiao Liu; Ning Wang; Janusz J. Zwiazek; Wenqing Zhang; Weihua Guo; Renqing Wang; Fengyu Zhang; et al. (Plant and Soil, 2023)

Establishment of regeneration system of Pyrus and the genetic stability analysis of regenerated population - Qi Liu; Yingjie Yang; Jianlong Liu; Jiankun Song; Dingli Li; Rencai Wang; Ran Wang (Plant Cell, Tissue and Organ Culture (PCTOC), 2023)

Receptor and Ionic Mechanism of Histamine on Mouse Dorsolateral Striatal Neurons - Jian-Ya Peng; Kang-Li Shen; Xiu-Juan Fan; Zeng-Xin Qi; Hui-Wei Huang; Jian-Lan Jiang; Jian-Hua Lu; Xiao-Qin Wang; Xiao-Xia Fang; Wang-Rui Yuan; Qiao-Xuan Deng; Shu Chen; et al. (Molecular Neurobiology, 2023)

Effects of iron and nitrogen-coupled cycles on cadmium availability in acidic paddy soil from Southern China - Yichun Li; Jianfeng Ning; Qi Li; Linfeng Li; Nanthi S. Bolan; Bhupinder Pal Singh; Hailong Wang (Journal of Soils and Sediments, 2023)

An Acid-triggered Reactive and Enhanced Fluorescent Probe for Selective Detection of Al3+/H+ and its Application in Real Water Samples and Living Cells - Zhigang Li; Bing Zhao; Wei Kan; Fanqiang Bu; Xin Qi; Liyan Wang; Bo Song; Limin Ding (Journal of Fluorescence, 2023)

Viperin deficiency promotes dendritic cell activation and function via NF-kappaB activation during Mycobacterium tuberculosis infection - Xinying Zhou; Hui Xu; Qianna Li; Qi Wang; Honglin Liu; Yingqi Huang; Yao Liang; Linmiao Lie; Zhenyu Han; Yaoxin Chen; Yulan Huang; Wenle Zhou; et al. (Inflammation Research, 2023)
Objectives and design Dendritic cells (DCs) are one of the key immune cells in bridging innate and adaptive immune response against Mycobacterium tuberculosis (Mtb) infection. Interferons (IFNs) play important roles in regulating DC activation and function. Virus-inhibitory protein, endoplasmic reticulum-associated, interferon-inducible (Viperin) is one of the important IFN-stimulated genes (ISGs), and elicits host defense against infection. Methods We investigated the effects and mechanisms of Viperin on DC activation and function using Viperin deficient bone marrow-derived dendritic cells (BMDCs) during Mtb infection. Results Viperin deficiency enhanced phagocytic activity and increased clearance of Mtb in DCs, produced higher abundance of NO, cytokine including interleukin-12 (IL-12), Tumor necrosis factor-α (TNF- α ), IL-1 β , IL-6 and chemokine including CXCL1, CXCL2 and CXCL10, elevated MHC I, MHC II and co-stimulatory molecules expression, and enhanced CD4 + and CD8 + T cell responses. Mechanistically, Viperin deficiency promoted DC activation and function through NF-κB p65 activation. NF-κB p65 inhibitor prevented cytokine and chemokine production, and co-stimulatory molecules expression promoted by Viperin deficiency. Conclusions These results suggest that Mtb induced Viperin expression could impair the activation of host defense function of DCs and DC-T cell cross talk during Mtb infection. This research may provide a potential target for future HDT in TB therapy.

Determining the position of a fish passage facility entrance based on endemic fish swimming abilities and flow field - Yunong Qin; Qi Wei; Qianfeng Ji; Kefeng Li; Ruifeng Liang; Yuanming Wang (Environmental Science and Pollution Research, 2023)

Application of quantitative analysis for aluminum alloy in femtosecond laser-ablation spark-induced breakdown spectroscopy using one-point and multi-line calibration - Jiale Li; Qi Yang; Jieqi Yao; Xiaoyong He; Fujuan Wang (Analytica Chimica Acta, 2023)

Identification of potassium transport proteins in algae and determination of their role under salt and saline-alkaline stress - Wenjie Li; Yuting Zhang; Huimin Ren; Zheng Wang; Yinghui OuYang; Shuo Wang; Jamshaid Hussain; Iftikhar Zeb; Youhan Kong; Shenkui Liu; Guoning Qi (Algal Research, 2023)

N2O emissions from soils under short-term straw return in a wheat-corn rotation system are associated with changes in the abundance of functional microbes - Jitong Lin; Zhiyu Xu; Yinghao Xue; Renhua Sun; Rongguang Yang; Xiaoxu Cao; Hui Li; Qi Shao; Yanhong Lou; Hui Wang; Quangang Yang; Hong Pan; et al. (Agriculture, Ecosystems & Environment, 2023)

Dibenzofurans from Crataegus oresbia and their lipid-lowering activity - Ying Wang; Li-Juan Lang; Qi-Jie Zhu; Xiu-Rong Wu; Lei Shen; Bei Jiang; Chao-Jiang Xiao (Natural Product Research, 2022)

The anti-inflammatory cytokine IL-22 exhibited a proinflammatory effect in the ovary aiding with the parturition of ovoviviparous black rockfish (Sebastes schlegelii) - Shaojing Yan; Likang Lyu; Xiaojie Wang; Haishen Wen; Yun Li; Jianshuang Li; Yijia Yao; Chenpeng Zuo; Songyang Xie; Zhijun Wang; Xin Qi (Frontiers in Marine Science, 2022)
Introduction As a unique type of immunological process, pregnancy and subsequent parturition are associated with a series of inflammatory events. As an anti-inflammatory cytokine, IL-22 has been proven to participate in the parturition process in mammals. However, less is known about ovoviviparous teleosts. To investigate the role of IL-22 in fish parturition, black rockfish, an ovoviviparous teleost, was used. This fish is unique in that it provides over 60% nutrition supply for over 50 thousand embryos at the same time though a placenta-like structure during pregnancy while delivering all fries in two hours. Methods Sequence alignment, phylogenetic tree analysis and homology modeling were performed on IL-22 and its receptor. In situ hybridization demonstrated ovarian localization of il22 and il22r1 . The protein of rIL-22 was obtained through the prokaryotic expression. RNA-seq analysis was performed on black rockfish ovarian cells treated with rIL-22. Results In situ hybridization results showed that both il22 and il22ra1 were localized in the perinatal follicle layer and embryonic envelope. The il22 expression level was significantly increased during parturition compared to before and after parturition ( P <0.05). To further understand the mechanism of IL-22 in parturition, rIL-22 was obtained. The downstream variation genes in primary cultured ovarian cells in the perinatal period were analyzed according to the transcriptomic results. A total of 168 differentially expressed genes (DEGs) were identified in the rIL-22 group compared with the PBS control group (padj < 0.05 and |log2FoldChange| 1). Of those, 134 DEGs were identified in the LPS and rIL-22 treatment groups, including chemokine, cytokine, and PG synthesis. 34 DEGs were mainly identified in immune-related pathways and reorganization of the cytoskeleton responded only to rIL-22 stimulation but not LPS. KEGG pathways mainly included immune response, PG synthesis, cell death and angiogenesis (p value < 0.05). Discussion Taken together, our results indicated that IL-22 plays an important role in the parturition of black rockfish by upregulating PG synthesis and increasing chemokine, proinflammatory factor, as well as PG synthetase levels.

Molecular detection and characterization of Enterocytozoon bieneusi in captive alpine musk deer (Moschus chrysogaster) in Central and Eastern of Gansu Province, China - Aiyun Zhao; Qilin Wang; Haixin Tuo; Fuchang Yu; Youwen Li; Meng Qi; Wei Zhao (Veterinary Research Communications, 2022)

Machine Learning-Enabled Determination of Diffuseness of Brain Arteriovenous Malformations from Magnetic Resonance Angiography - Yuming Jiao; Jun-Ze Zhang; Qi Zhao; Jia-Qi Liu; Zhen-Zhou Wu; Yan Li; Hao Li; Wei-Lun Fu; Jian-Cong Weng; Ran Huo; Shao-Zhi Zhao; Shuo Wang; et al. (Translational Stroke Research, 2022)

Structural and functional analysis of a potent human neutralizing antibody against enterovirus A71 - Zhe Chen; Linlin Bao; Bin Zhu; Hua Fu; Shuangli Zhu; Tianjiao Ji; Ying Xue; Chuan Liu; Xurong Wang; Fengdi Li; Qi Lv; Feifei Qi; et al. (Science China Life Sciences, 2022)

Security risk assessment and visualization study of key nodes of sea lanes: case studies on the Tsugaru Strait and the Makassar Strait - Li Xiao; Shaoyang Chen; Shun Xiong; Peixin Qi; Tingting Wang; Yanwei Gong; Na Liu (Natural Hazards, 2022)

Talaromyces marneffei Infections in 8 Chinese Children with Inborn Errors of Immunity - Linlin Wang; Ying Luo; Xiaolin Li; Yixian Li; Yu Xia; Tingyan He; Yanyan Huang; Yongbin Xu; Zhi Yang; Jiayun Ling; Ruohang Weng; Xiaona Zhu; et al. (Mycopathologia, 2022)
Purpose Talaromyces marneffei (TM) is an opportunistic fungus leading to multi-organ damages and poor prognosis in immunocompromised individuals. TM infections in children are rare and our knowledge to TM infection is insufficient. To investigate the clinical characteristics of TM-infected children and to explore the underlying mechanisms for host against TM, we analysed TM-infected patients diagnosed in our hospital. Methods Eight patients with TM infections have been identified in Shenzhen Children’s Hospital during 2017–2021. Clinical data were collected from medical records. Immunological features were evaluated by flow cytometry. Literatures were also reviewed to summarize the reported inborn errors of immunity (IEIs) with TM infections. Results All 8 children were HIV-negative. The most common symptom of TM infections was fever (8/8), followed by weight loss (7/8), pneumonia (7/8), hepatomegaly (7/8), splenomegaly (6/8), anemia (6/8), lymphadenopathy (5/8), thrombocytopenia (3/8), diarrhea (3/8), rashes or skin lesions (3/8), and osteolytic lesions (1/8). Five children died during the follow-ups. CD3+ T cells were decreased in 6 patients. Eight patients had reduced natural killer cells. All patients went gene sequencing and were finally diagnosed as IEIs, including STAT1 gain-of-function, IL-2 receptor common gamma chain deficiency, adenosine deaminase deficiency, CD40 ligand deficiency, and STAT3 deficiency. Another 4 types of IEIs (CARD9, IFN- γ receptor 1, RelB, and NFKB2 deficiency), have been reported with TM infections based on literature review. Conclusion TM infections resulted in systemic injuries and high mortality. The spectrum of IEIs underlying TM infections indicated that T cell-mediated immunity, IFN- γ , IL-17 signalings and NF-κB pathways were important for host responses against TM infection. In reverse, for HIV-negative children without other secondary immunodeficiencies, IEIs should be considered in TM-infected children.

Transcranial Direct-Current Stimulation Regulates MCT1-PPA-PTEN-LONP1 Signaling to Confer Neuroprotection After Rat Cerebral Ischemia–Reperfusion Injury - Xiangyi Kong; Wenjie Hu; Yu Cui; Jingchen Gao; Xujin Yao; Jinyang Ren; Tao Lin; Jiangdong Sun; Yunyi Gao; Xiaohua Li; Hui Wang; Huanting Li; et al. (Molecular Neurobiology, 2022)
Propionic acid (PPA) is a critical metabolite involved in microbial fermentation, which functions to reduce fat production, inhibit inflammation, and reduce serum cholesterol levels. The role of PPA in the context of cerebral ischemia–reperfusion (I/R) injury has yet to be clarified. Increasing evidence indicate that transcranial direct-current stimulation (tDCS) is a safe approach that confers neuroprotection in cerebral ischemia injury. Here, we show that the levels of PPA were reduced in the ischemic brain following a rat cerebral I/R injury and in the cultured rat cortical neurons after oxygen–glucose deprivation (OGD), an in vitro model of ischemic injury. We found that the decreased levels of transporter protein monocarboxylate transporter-1 (MCT1) were responsible for the OGD-induced reduction of PPA. Supplementing PPA reduced ischemia-induced neuronal death after I/R. Moreover, our results revealed that the neuroprotective effect of PPA is mediated through downregulation of phosphatase PTEN and subsequent upregulation of Lon protease 1 (LONP1). We demonstrated that direct-current stimulation (DCS) increased MCT1 expression and PPA level in OGD-insulted neurons, while tDCS decreased the brain infarct volume in the MCAO rats via increasing the levels of MCT1 expression and PPA. This study supports a potential application of tDCS in ischemic stroke.

Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson’s Disease - Cheng-Jie Li; Li-Ge Zhang; Lu-Bing Liu; Meng-Qi An; Li-guo Dong; Han-Ying Gu; Yong-Ping Dai; Fen Wang; Cheng-Jie Mao; Chun-Feng Liu (Molecular Neurobiology, 2022)

Correction to: Involvement of regulation of the excitation:inhibition functional balance in the mPFC in the antidepressant-anxiolytic effect of YL-IPA08, a novel TSPO ligand - Jin Yuan; Jun-Qi Yao; Xin-Xin Fang; Wei Dai; Yun-Hui Wang; Li-Ming Zhang; Yun-Feng Li (Metabolic Brain Disease, 2022)

Antidepressant effects of cherry leaf decoction on a chronic unpredictable mild stress rat model based on the Glu/GABA-Gln metabolic loop - Chuan Jiang; Hua Wang; Jiaying Qi; Jinghan Li; Qianqian He; Chaonan Wang; Yonggang Gao (Metabolic Brain Disease, 2022)

High Concentration of CO2 Improve the Pb Resistance of Oryza sativa L. Seedlings by Enhancing Photosynthesis and Regulating Plant Endogenous Hormones - Xuhao Wang; Jiayi Zou; Xiufen Qi; Qi Li; Lianju Ma; Yueying Li; Xuemei Li; Lanlan Wang (Journal of Plant Growth Regulation, 2022)

Inoculation with Arbuscular Mycorrhizal Fungi Reinforces Tea Plant’s Tolerance to Salinity - Shasha Guo; Qi Wang; Lei Tang; Tianxin Zhang; Jiayang Li; Yao Xiao; Yuefang Gao; Juan Bai; Bin Xiao; Chunmei Gong (Journal of Plant Growth Regulation, 2022)

An association study on the risk, glucocorticoids effectiveness, and prognosis of systemic lupus erythematosus: insight from mitochondrial DNA copy number - Zhen Li; Qi-Qun Zong; Chun-Xia Zhai; Guang-Hui Yu; Wan-Qin Hu; Yu-Hua Wang; Lin-Lin Wang; Zi-Ye Yan; Ting-Yu Zhang; Ying Teng; Shuang Liu; Jing Cai; et al. (Immunologic Research, 2022)

Genome-wide identification and expression of the peroxisome proliferator-activated receptor gene family in the Tibetan highland fish Gymnocypris przewalskii - Xiaohuan Li; Sijia Liu; Delin Qi; Hongfang Qi; Yang Wang; Kai Zhao; Fei Tian (Fish Physiology and Biochemistry, 2022)

Characteristic pollutants risk assessment of modified manganese residue utilization in sintered product - Chao-qiang Wang; Ke Liu; De-ming Huang; Qi-cong Huang; Pei-xin Wang; Xu-dong Mei; Shu-chun Li (Environmental Science and Pollution Research, 2022)

Desulphurization mechanism and engineering practice of carbide slag - Jiamin Qi; Pengxiang Zhou; Di Yang; Zixuan Wang; Bin Li (Environmental Science and Pollution Research, 2022)

Exploring the Wenchuan earthquake fault through the accurate location of WFSD-4# Well using seismic reflection - Yang-Yang Feng; Chang-Qing Yu; Hai-Bing Li; Chen Qu; Chan Wu; Qi Wang; Su Luo; Jin-Peng Huang; Ghazi Rehana (Applied Geophysics, 2022)

Removal of Cd from contaminated farmland soil by washing with residues of traditional Chinese herbal medicine extracts - Yi Wang; Yuan Li; Shuai Yang; Qi-hao Wang; Shao-cheng Si; Han-yi Mei; Guo-ming Liu; Xiang-liang Pan; Yong-ming Luo (Environmental Science and Pollution Research, 2022)

Study on the enantioselective bioaccumulation and dissipation of uniconazole enantiomers in earthworm-soil microcosm through supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS) - Chunhong Teng; Ying Li; Tao Cang; Hao Xu; Zhenzhen Liu; Peipei Qi; Zhiwei Wang; Huiyu Zhao; Shanshan Di; Xinquan Wang (Environmental Science and Pollution Research, 2022)

Lateral Bearing Capacity of a Hybrid Monopile: Combined Effects of Wing Configuration and Local Scour - Biao Li; Yifa Wang; Wengang Qi; Shunyi Wang; Fuping Gao (Journal of Marine Science and Engineering, 2022)
Pile foundations for offshore wind turbines are subjected to large lateral loads. By mounting wings on the perimeter of regular monopiles, winged monopiles have shown better performance in resisting deformation under horizontal loading. However, the hazardous effect of local scour on the lateral bearing capacity of winged monopiles installed in the sandy seabed has not been systematically evaluated. In this study, a modified Mohr–Coulomb model considering the pre-peak hardening and post-peak softening behavior of dense sand is adopted to simulate laterally loaded winged monopiles in the locally scoured sandy seabed, using three-dimensional finite element analyses. The effect of local scour depth on the lateral capacity of winged monopiles is examined and explained by soil failure mechanisms. The enhancement of lateral capacity with wings attached to the monopile is demonstrated to be more effective than extending pile embedment length. The effects of the relative density of sand and the wing load orientation are also discussed. Finally, the wing efficiency is evaluated to determine the optimal configuration of winged monopiles.

Preparation and properties of zeolite-fly ash-slag composite porous materials: CO2 adsorption performance and mechanical property - Wei Lu; Juan Li; Guansheng Qi; Xiangming Hu; Qian Zhang; Mingjun Wang; Maoyuan Zhang (Environmental Science and Pollution Research, 2022)

Association of soft drink and 100% fruit juice consumption with all-cause mortality, cardiovascular diseases mortality, and cancer mortality: A systematic review and dose-response meta-analysis of prospective cohort studies - Bei Pan; Long Ge; Honghao Lai; Qi Wang; Qi Wang; Qian Zhang; Min Yin; Sheng Li; Jinhui Tian; Kehu Yang; Jiancheng Wang (Critical Reviews in Food Science and Nutrition, 2022)

Two new sesquiterpenoid lactone derivatives from Lindera aggregata - Song-Song Wen; Yan Wang; Jia-Ping Xu; Qi Liu; Lei Zhang; Jing Zheng; Lin Li; Na Zhang; Xin Liu; Yu-Wen Xu; Zhen-Liang Sun (Natural Product Research, 2022)

Involvement of osmoregulation, glyoxalase, and non-glyoxalase systems in signaling molecule glutamic acid-boosted thermotolerance in maize seedlings - Xue-Mei Qiu; Yu-Ying Sun; Jia-Qi Wang; Ru-Hua Xiang; Zhong-Guang Li (Protoplasma, 2022)

Senegenin Rescues PC12 Cells with Oxidative Damage Through Inhibition of Ferroptosis - Heping Zhang; Wei Zhou; Jianling Li; Zhaohui Qiu; Xiaotong Wang; Hui Xu; Huadong Wang; Daxiang Lu; Renbin Qi (Molecular Neurobiology, 2022)

Bone Marrow Mesenchymal Stem Cell Exosome Attenuates Inflammasome-Related Pyroptosis via Delivering circ_003564 to Improve the Recovery of Spinal Cord Injury - Yanyin Zhao; Yu Chen; Zhiwei Wang; Changli Xu; Suchi Qiao; Tianze Liu; Ke Qi; Dake Tong; Cheng Li (Molecular Neurobiology, 2022)

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice - Bo Yang; Zhan Gao; Qi-Shuang Li; Xiang-Ye Zhang; Lan Song; Yi-Ni Wang; Xin-Yue Wang; Lin-Lin Ji; Hong-Liang Xu; Hui Xie; Fu-Kai Feng; Xiao-Ping Li; et al. (Inflammation Research, 2022)

Cost-effective microwave-assisted hydrothermal rapid synthesis of analcime-activated carbon composite from coal gangue used for Pb2+ adsorption - Qi Li; Liang Lv; Xudong Zhao; Yong Wang; Yongzhen Wang (Environmental Science and Pollution Research, 2022)

Dynamic evolution and the mechanism of modern gully agriculture regional function in the Loess Plateau - Lulu Qu; Yurui Li; Yongsheng Wang; Shijie Dong; Qi Wen (Journal of Geographical Sciences, 2022)

Genetic variations in the bitter taste receptor gene TAS2R38 are related to cigarette smoking behavior in Han Chinese smokers - Fei-Yan Qi; Zhou-Hai Zhu; Meng Li; Ying Guan; Qi-Yuan Peng; She-Ming Lu; Zhi-Hua Liu; Ming-Feng Wang; Ming-Ming Miao; Zhang-Yu Chen; Xue-Mei Li; Jie Bai; et al. (Genes & Genomics, 2022)

mTORC1/C2 regulate spermatogenesis in Eriocheir sinensis via alterations in the actin filament network and cell junctions - Zhen-Fang Li; Shuang-Li Hao; Lan-Min Wang; Hong-Yu Qi; Jia-Ming Wang; Fu-Qing Tan; Wan-Xi Yang (Cell and Tissue Research, 2022)

Electromagnetic radiation characteristics of coal under multiple loading methods and its relationship with porosity - Qi Zhang; Xiangchun Li; Zhanwen Fan; Mingxiu Xing; Yinqing Wang; Kedi Wang; Yaoyu Shi (Arabian Journal of Geosciences, 2022)

Increased microbial and substrate complexity result in higher molecular diversity of the dissolved organic matter pool - Qi Chen; Christian Lønborg; Feng Chen; Michael Gonsior; Yunyun Li; Ruanhong Cai; Chen He; Jiaxin Chen; Yu Wang; Quan Shi; Nianzhi Jiao; Qiang Zheng (Limnology and Oceanography, 2022)
Marine dissolved organic matter (DOM) represents one of the largest reduced carbon pools on Earth. Diverse microbial metabolic activities play important roles in shaping this pool. However, the links between changing DOM substrates and microbial communities and its influence on the microbial produced DOM remain poorly understood. In this study, we investigated how the addition of substrates with different complexity (glucose, laminarin, and Synechococcus ‐derived DOM) impacted the production of new DOM by an individual opportunist Alteromonas strain and a coastal natural microbial community. Our experiments reveal that the microbial complexity was more important than the substrate in shaping the molecular composition of DOM. Furthermore, our results showed that the DOM composition played a larger role in shaping the microbial compositions than the concentrations of DOM and inorganic nutrients. Combined our network analysis revealed that complex substrates resulted in higher molecular diversity of the microbial produced DOM, sustained a higher microbial diversity, and maintained a more diverse association between microbial communities and DOM molecules. Overall, the present study indicate that the microbial diversity contributes to DOM molecular diversity and vice versa, highlighting the importance of microbial–substrate interactions in shaping the marine DOM pool.

Research on renewable energy prediction technology: empirical analysis for Argentina and China - Guomin Li; Jingchao Wang; Zihan Qi; Tao Wang; Yufei Ren; Yagang Zhang; Gengyin Li (Environmental Science and Pollution Research, 2022)

Activated sludge process enabling highly efficient removal of heavy metal in wastewater - Guo-hua Liu; Xiangnan Tang; Junli Yuan; Qiangang Li; Lu Qi; Hongchen Wang; Zhengfang Ye; Quanlin Zhao (Environmental Science and Pollution Research, 2022)

First report of Claviceps purpurea causing ergot disease on wheat (Triticum aestivum) in southwestern China - Mingliang Ding; Zhiqin Wang; Qi Fan; Hefa Liao; Kun Liu; Mingju Li; Zhanhong Ma; Hong Yu; Yuanbing Wang (Journal of Plant Pathology, 2022)

Two new aromatic derivatives from Codonopsis pilosula and their α-glucosidase inhibitory activities - Ru-Yue Wang; Pan-Jie Su; Bing Li; Xiao-Qing Zhan; Feng-Ming Qi; Chun-Wei Lv; Fang-Di Hu; Kun Gao; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

Variation in soybean root-associated microbiome between lateral roots with and without nodules - Jiamin Gao; Shi Chen; Yang Wang; Jiejun Qi; Xiaomeng Li; Gehong Wei; Shuo Jiao (Plant and Soil, 2022)

Transdermal Delivery of Metformin Utilizing Ionic Liquid Technology: Insight Into the Relationship Between Counterion Structures and Properties - Minghuang Hong; Qinglin Wang; Kai Wang; Jinghui Li; Ming-Hui Qi; Guo-Bin Ren (Pharmaceutical Research, 2022)

Enhanced M-CSF/CSF1R Signaling Closely Associates with PrPSc Accumulation in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents - Ying Xia; Cao Chen; Jia Chen; Chao Hu; Wei Yang; Lin Wang; Lian Liu; Li-Ping Gao; Yue-Zhang Wu; Dong-Dong Chen; Qi Shi; Zhi-Bao Chen; et al. (Molecular Neurobiology, 2022)

Involvement of regulation of the excitation:inhibition functional balance in the mPFC in the antidepressant-anxiolytic effect of YL-IPA08, a novel TSPO ligand - Jin Yuan; Jun-Qi Yao; Xin-Xin Fang; Wei Dai; Yun-Hui Wang; Li-Ming Zhang; Yun-Feng Li (Metabolic Brain Disease, 2022)

UPF1 increases amino acid levels and promotes cell proliferation in lung adenocarcinoma via the eIF2α-ATF4 axis - Lei Fang; Huan Qi; Peng Wang; Shiqing Wang; Tianjiao Li; Tian Xia; Hailong Piao; Chundong Gu (Journal of Zhejiang University-SCIENCE B, 2022)

Changes of production and consumption structures in coastal regions lead to mercury emission control in China - Qiumeng Zhong; Hui Li; Sai Liang; Jetashree; Xiaohui Wu; Jianchuan Qi; Shuxiao Wang (Journal of Industrial Ecology, 2022)
China is important in the global mercury (Hg) cycle and is experiencing substantial economic structure transitions. There are pronounced differences in economic development, industrial structure, and consumption patterns across regions in China. However, the impacts of regional economic structure transitions (i.e., production and final demand structures) on Hg emissions in China remain unknown. Here, we reveal the transboundary impacts of changes in regional economic structures on provincial Hg emissions in China. We found that the transitions of production and final demand structures in coastal regions led to Hg emission reductions in China during 2007–2017. In particular, production structure changes in East Coast contributed to 36 metric tons of national Hg emission reduction, where 28 metric tons occurred in other regions (especially Hebei). Its final demand structure transition contributed to 19 metric tons of national emission reduction, where 15 metric tons occurred in other regions (especially Henan). Unfortunately, production structure changes in Northwest and final demand structure changes in Southwest contributed to Hg emission increments in China during 2007–2017. For instance, changes in the final demand structure of Southwest caused 34 metric tons of emission increments, mainly from provinces within the region. Thus, spatially explicit measures for China's Hg emission control can focus on the optimizations of production structure in Northwest and final demand structure in Southwest, as well as the promotion of interregional joint actions between East Coast and North China (especially Hebei and Henan). The findings of this study can inform region‐specific policy decisions and interregional joint efforts to control Hg emissions around the world.

Co‐benefits analysis of industrial symbiosis in China's key industries: Case of steel, cement, and power industries - Qi Zhang; Ting Xiang; Wei Zhang; Heming Wang; Jing An; Xiuping Li; Bing Xue (Journal of Industrial Ecology, 2022)
Accelerating the construction of ecological civilization in the industrial field and guiding the transformation of industry toward a green direction have become a national development strategy. Promoting the coordinated development of energy‐intensive industries such as steel, cement, and power is a key breakthrough in achieving the green transformation of various industries. This study has designed a steel–cement–power polygeneration system with the collaborative utilization of solid waste resources as the ecological link point. Four scenarios, including business‐as‐usual, optimization of product structure, low‐carbon technology application, and policy advancement (PAD), were established to assess the overall energy‐saving and emissions reduction potential of the steel–cement–power polygeneration system from 2015 to 2050. The results show that product structure adjustment and industrial symbiosis have a significant impact on energy saving and emission reduction of key industries. In 2050, the total energy consumption and carbon emissions of the polygeneration system could reach 38,697.64 PJ and 3766.73 Mt CO 2 . Based on the scenario analysis, the production and use of solid waste in the polygeneration system and the economic benefits are also discussed. Under the PAD scenario, by 2050, the proportion of fly ash as cement raw material will increase to 41%, while the supply of blast furnace slag may be insufficient, and the comprehensive utilization of solid waste can bring economic benefits of 238.32 billion Yuan to the system.

Livin promotes Th2-type immune response in airway allergic diseases - Yue Wang; Zhiyu Xiang; Miaomiao An; Huijing Jia; Chunyan Bu; Yanfeng Xue; Yao Wei; Ruiying Li; Xueping Qi; Fengli Cheng; Changqing Zhao; Jinmei Xue; et al. (Immunologic Research, 2022)
Objectives To investigate the effects of livin on the Th2 immune response in airway allergic diseases (AAD) and explore the interaction among livin, GATA3, IL-4 in peripheral blood CD4 + T cells of AAD patients. Methods WT mice and livin KO mice were developed for model of AAD. Th2 cell levels in the lung tissues and spleen were assessed by flow cytometry. Also, it was assessed in the culture after exposing to livin inhibitor (Lp-15); the protein and mRNA levels of livin, GATA3 and IL-4 in peripheral blood CD4 + T cells isolated from patients with or without AAD were measured by real-time quantitative polymerase chain reaction (RT-qPCR) and Western blotting, respectively. Finally, Co-immunoprecipitation (Co-IP) was employed to identify the interaction between livin and GATA3. Results Compared with WT mouse, Th2 cell frequency in lung tissues and spleen was significantly decreased in livin KO mouse; after adding Lp-15, the differentiation from Naive CD4 + T cells in spleen to Th2 cells was blocked; the protein and mRNA levels of livin, GATA3 and IL-4 in AAD group were higher than that in control group. The levels of livin were positively correlated with IL-4, and GATA3 was also positively correlated with IL-4 and livin. GATA3 was detected in the protein complex co-precipitated with livin antibody, and livin was also detected in the protein complex co-precipitated by GATA3 antibody. Conclusion Livin increases the expression of IL-4 and facilitates naive CD4 + T cells to differentiate into Th2 cells, which triggers airway allergy.

Comparative transcriptome analyses identify genes involved into the biosynthesis of forsythin and forsythoside A in Forsythia suspensa - Wang Jun Yuan; Su Ping Zhang; Zhi Yin He; Yan Xia He; She Qi He; Li Jun Liu; Xin Sun; Qin Li (Functional & Integrative Genomics, 2022)

Dietary supplementation of two indigenous Bacillus spp on the intestinal morphology, intestinal immune barrier and intestinal microbial diversity of Rhynchocypris lagowskii - Xin-yu Lei; Dong-ming Zhang; Qiu-ju Wang; Gui-qin Wang; Yue-hong Li; Yu-rou Zhang; Men-nan Yu; Qi Yao; Yu-ke Chen; Zhi-xin Guo (Fish Physiology and Biochemistry, 2022)

Cumulative risk assessment of dietary exposure to phthalates in pregnant women in Beijing, China - Danping Shan; Tao Zhang; Ludi Li; Yuqing Sun; Di Wang; Yingzi Li; Zheng Yang; Kanglong Cui; Shaowei Wu; Lei Jin; Bo Hong; Xuejun Shang; et al. (Environmental Science and Pollution Research, 2022)

Oligo replication advantage driven by GC content and Gibbs free energy - Hongyan Qiao; Yanmin Gao; Qian Liu; Yanan Wei; Jiaojiao Li; Zhaoguan Wang; Hao Qi (Biotechnology Letters, 2022)

Brain structural connectivity sub typing in unilateral temporal lobe epilepsy - Zhensheng Li; Che Jiang; Wei Xiang; Zijuan Qi; Quwen Gao; Kairun Peng; Jian Lin; Wei Wang; Weimin Wang; Bingmei Deng (Brain Imaging and Behavior, 2022)

A Label-Free Colorimetric Aptasensor Containing DNA Triplex Molecular Switch and AuNP Nanozyme for Highly Sensitive Detection of Saxitoxin - Xiaoyan Qi; Ling Li; Xiaochen Yan; Yinglin Zhao; Lele Wang; Rui Ma; Sai Wang; Xiangzhao Mao (Journal of Ocean University of China, 2022)

Origin and Implications of Pollution in Coastal Groundwater of the Guangdong Province - Chenzhe Li; Tengfei Fu; Yushan Fu; Zhenyan Wang; Bin Li; Chen Qi; Guangquan Chen; Xingyong Xu; Hongjun Yu (Journal of Marine Science and Engineering, 2022)
The groundwater resource is crucial to the urbanization and industrialization in the Guangdong coastal area; the rapid development of Daya Bay has presented a challenge for the management of the groundwater quantity and quality. Therefore, a novel approach to hydrochemical analysis, which, combined with the health risk model and the water quality index (WQI), was used to explain the hydrochemistry characteristics and risks to human health of groundwater in the Guangdong coastal areas in addition to investigating the factors controlling groundwater quality. The results showed that the average concentration of total dissolved solids (TDS) in groundwater was 1935.26 mg/L and the quality of water was weakly alkaline. The dominant hydrochemical types of groundwater were identified to be Mg-HCO3 and Na-Cl·HCO3. The main factor influencing the hydrochemical composition was rock weathering, while the result of principal component analysis (PCA) shows seawater intrusion and anthropogenic inputs also have an effect on the water quality. The conclusions of the water quality assessment indicated that most of the groundwater samples were acceptable for drinking. However, both WQI and the non-carcinogenic hazard quotient (HQ) values indicated unacceptable risks in any area of Maoming, Zhanjiang and Shantou, and, according to the hazard index (HI) value, children in the study area are at more danger to health risks than adults. It is suggested that both groundwater salinization and nitrate pollution should be paid attention to when improving groundwater quality and exploring the sustainable utilization of groundwater resources.

The complete paternally inherited mitochondrial genomes of three clam species in genus Macridiscus (Bivalvia: Veneridae): A TDRL model of dimer-mitogenome rearrangement of doubly uniparental inheritance - Rui Wang; Xuanzhao Li; Jiwei Qi (Frontiers in Marine Science, 2022)
One of the most striking exceptions to strict maternal inheritance of mitochondrial DNA (mtDNA) in the animal kingdom is a system called doubly uniparental inheritance (DUI), which exists in several bivalve species. DUI is characterized by the presence of two distinct sex-associated mitochondrial lineages: one transmitted through eggs (F-type mtDNA) and the other through sperm (M-type mtDNA). Presently, most known species exhibiting DUI belong to the freshwater bivalve order Unionoida. Other groups with species exhibiting DUI include the orders Mytiloida, Veneroida, and Nuculanoida. In Veneroida, the complete M-type mtDNA is available for two species. We report the presence of DUI in three species belonging to genus Macridiscus ( Macridiscus melanaegis , Macridiscus multifarious , and Macridiscus semicancellata ), in the order Veneroida, further obtaining their complete M-type mitogenomes. The M-type mitogenome sizes for M. melanaegis , M. multifarious , and M. semicancellata were 19,019 bp, 18,694 bp, and 18,726 bp, respectively, and the mean nucleotide difference between M-type and F-type mitogenomes was 21–23%. We compared the M-type and F-type mitogenomes and found that they show roughly the same genome features, except for gene order. In phylogenetic analyses of Veneroida, a “gender-joining” pattern was revealed within Macridiscus , similar to the pattern of “partial” Mytilus complex (except Unionida). This new insight provides novel evidence supporting the theory that Veneroida and Mytiloida have a more similar DUI pattern than Unionida. A large-scale rearrangement between the sex-linked mitogenomes of the three Macridiscus species was reported. From the observed rearrangement patterns, gene rearrangement between the two sex-linked mitogenomes could be explained by the tandem duplication and random loss (TDRL) model of dimer-mitogenome. This is the first report of heterogeneous genomes with two types of large-scale arrangements in the same organism, and may be contribute significantly to the study of mitochondrial recombination mechanisms.

Ice-Water-Gas Interaction during Icebreaking by an Airgun Bubble - Qi-Gang Wu; Zuo-Cheng Wang; Bao-Yu Ni; Guang-Yu Yuan; Yuriy A. Semenov; Zhi-Yuan Li; Yan-Zhuo Xue (Journal of Marine Science and Engineering, 2022)
When an airgun releases high-pressure gas underwater below an ice plate, it is observed that a bubble is formed rapidly while the ice plate is broken fiercely. In order to study the ice-water-gas interaction during this transient and violent phenomenon, a set of laboratory-scale devices was designed and a series of icebreaking experiments were carried out. High-speed photography was used to capture the evolution of the bubble and the ice plate. It was found that the airgun bubble had a unique ‘pear’ shape compared with the spherical bubble generated by electric sparking. The pressure induced by the pulsation of the airgun bubble near a rigid wall was measured by the pressure sensor. The initial shockwave, oscillatory pressure peaks caused by the directional fast air injection, secondary shockwave, and pressure peak caused by the bubble jet impact were clearly recorded. Three damage patterns of ice plates were observed and corresponding reasons were analyzed. The influence of dimensionless parameters, such as airgun-ice distance H and ice thickness T, was also investigated. The physical mechanism of ice-water-gas interaction was summarized.

Residual analysis of QoI fungicides in multiple (six) types of aquatic organisms by UPLC-MS/MS under acutely toxic conditions - Hong Li; Shuai Hu; Fengshou Sun; Qi Sun; Ning Wang; Beixing Li; Nan Zou; Jin Lin; Wei Mu; Xiuyu Pang (Environmental Science and Pollution Research, 2022)

3D food printing: Applications of plant-based materials in extrusion-based food printing - Mingshuang Wang; Dongnan Li; Zhihuan Zang; Xiyun Sun; Hui Tan; Xu Si; Jinlong Tian; Wei Teng; Jiaxin Wang; Qi Liang; Yiwen Bao; Bin Li; et al. (Critical Reviews in Food Science and Nutrition, 2022)

From ambiguity to transparency: influence of environmental information disclosure on financial performance in the context of internationalization - Ge Wang; Qi’ang Du; Xiaodong Li; Xiaopeng Deng; Yanliang Niu (Environmental Science and Pollution Research, 2022)

Effect of Surfactants with Different Hydrophilic–Lipophilic Balance on the Cohesive Force between Cyclopentane Hydrate Particles - Qingchao Fang; Xin Zhao; Sunbo Li; Zhengsong Qiu; Zhiyuan Wang; Qi Geng (Journal of Marine Science and Engineering, 2022)
Effective control of the cohesive force between hydrate particles is the key to prevent their aggregation, which then causes pipeline blockage. The hydrophilic–lipophilic balance (HLB) value of surfactants was proposed as an important parameter for the evaluation and design of hydrate anti-agglomerants. A microscopic manipulation method was used to measure the cohesive forces between cyclopentane hydrate particles in the presence of Tween and Span series surfactants with different HLB values; moreover, the measured cohesive force was compared with the results of calculations based on the liquid bridge force model. Combined with the surface morphology and wettability of the hydrate particles, we analyzed the mechanism by which surfactants with different HLB values influence the cohesion between hydrate particles. The results show that for both Tween (hydrophilic, HLB > 10) and Span (hydrophobic, HLB

Proteomic analysis of the spineless cuttlefish Sepiella japonica: Exploratory analyses on the phenomenon of death after spawning - Hongfei Li; Shuangrui Lin; Pengzhi Qi; Jingtian Wang; Meihua Fan; Hongwei Huang; Zhenyu Dong; Kaida Xu; Baoying Guo (Frontiers in Marine Science, 2022)
To better understand the physiological events involving death after spawning in S. japonica (Japanese spineless cuttlefish), we have presently generated a proteomic data set to properly examine this phenomenon. As such, a proteomic-based approach was employed to identify differentially expressed proteins (DEPs) in the optic glands of S. japonica , at three distinct growth stages: pre-spawning after sexual maturity (group A); spawning (group B) and postspawning before death (group C). About 955, 1000, and 1024 DEPs were identified for each comparative group analysis (i.e., group B vs A, group B vs C, and group C vs A). We further discovered that the function of these newly identified DEPs was mostly related to molecular events such as gene translation and signal transduction. According to the enriched GO terms obtained by Gene Ontology analysis, the function of most DEPs was correlated with structural molecule activity, ribosome function and gene expression. The majority of DEPs were known to be involved in signal transduction and energy metabolism, interestingly, some aging-related DEPs were also identified. Putting together, our study provides new insights, at the protein level, in the phenomenon of death after spawning in S. japonica , by referring to anti-aging effects conserved in other cephalopoda species.

Effect modification by aging on the associations of nicotine exposure with cognitive impairment among Chinese elderly - Jian Hou; Chao Huang; Bo Zhu; Wei Liu; Qing-qing Zhu; Lu Wang; Tian Li; Chun-jie Yuan; Shao-yang Lai; De-sheng Wu; Fei-qi Zhu; Jia-fei Zhang; et al. (Environmental Science and Pollution Research, 2022)

A novel method for simultaneous analysis of particle size and mineralogy for Chang’E-5 lunar soil with minimum sample consumption - Kenan Cao; Mingtan Dong; Zhenbing She; Qian Xiao; Xinyi Wang; Yuqi Qian; Yiheng Li; Zaicong Wang; Qi He; Xiang Wu; Keqing Zong; Zhaochu Hu; et al. (Science China Earth Sciences, 2022)

Transgenic expression of rice OsPHR2 increases phosphorus uptake and yield in wheat - Yan Li; Yuhui Fang; Chaojun Peng; Xia Hua; Yu Zhang; Xueli Qi; Zhengling Li; Yumin Wang; Lin Hu; Weigang Xu (Protoplasma, 2022)

Two-stage hybrid network for segmentation of COVID-19 pneumonia lesions in CT images: a multicenter study - Yaxin Shang; Zechen Wei; Hui Hui; Xiaohu Li; Liang Li; Yongqiang Yu; Ligong Lu; Li Li; Hongjun Li; Qi Yang; Meiyun Wang; Meixiao Zhan; et al. (Medical & Biological Engineering & Computing, 2022)

Molecular detection of spotted fever group rickettsiae in hedgehogs (Erinaceus amurensis) and hedgehog-attached ticks in Xuyi County, Southeast China - Changqiang Zhu; Lele Ai; Yong Qi; Yunsheng Liu; Hong Li; Fuqiang Ye; Qiuwei Wang; Yizhe Luo; Weilong Tan; Chunmeng Shi (Experimental and Applied Acarology, 2022)
Tick-borne diseases like Rickettsia , Anaplasma and Ehrlichia are widespread infectious zoonoses that threaten the health of both humans and animals worldwide. Ticks and their hosts, such as hedgehogs, can play a crucial role in transmitting tick-borne diseases and the cycle of Rickettsia . To investigate the presence and identity of Rickettsia in hedgehogs and hedgehog-attached ticks in Xuyi County, Southeast China, 114 ticks were collected from 45 hedgehogs captured totally. Via morphological and molecular methods, all these ticks were identified as two species: Haemaphysalis flava (110/114, 96.5%) and Haemaphysalis longicornis (4/114, 3.5%). Rickettsia spp. were genotypically characterized by PCR targeting rrs , gltA , ompA , ompB , and sca4 gene fragments. The prevalence of spotted fever group rickettsiae (SFGR) infection found in hedgehogs and ticks was 17.8% (8/45) and 78.1% (89/114), respectively. Phylogenetic analyses demonstrated that those Rickettsia spp. belong to two species: Rickettsia heilongjiangensis ( R. heilongjiangensis XY-1) and a potential new species, Candidatus Rickettsia xuyiensis XY-2. The present study gave the first evidence of R. heilongjiangensis and Candidatus R. xuyiensis in ticks and hedgehogs of Southeast China. Our findings suggest that hedgehogs might be involved in the natural transmission cycle of Rickettsia species.

Assessing the sustainability and competitiveness of tourism economies in China’s Chengdu-Chongqing metropolitan area - Wen Wang; Shi-Qi Wang; Ye-Shan Li; Chao Feng (Environmental Science and Pollution Research, 2022)

Effects of perfluorooctanoic acid (PFOA) on activated sludge microbial community under aerobic and anaerobic conditions - Duanyi Huang; Rui Xu; Xiaoxu Sun; Yongbin Li; Enzong Xiao; Zhimin Xu; Qi Wang; Pin Gao; Zhaohui Yang; Hanzhi Lin; Weimin Sun (Environmental Science and Pollution Research, 2022)

Uncertainty or trust? Political trust, perceived uncertainty and public acceptance of personal carbon trading policy - Lan Gao; Jingjing Jiang; Haonan He; Qi Zhou; Shanyong Wang; Jun Li (Environmental Geochemistry and Health, 2022)

Human Adipose-Derived Stem Cells Delay Muscular Atrophy after Peripheral Nerve Injury in Rats - Siwei Qu; Ning Ma; Weixin Wang; Sen Chen; Qi Wu; Yangqun Li; Zhe Yang (Cell Biochemistry and Biophysics, 2022)

Molecular characterization of a new fusarivirus infecting Botryosphaeria dothidea, the causal agent of pear ring rot disease - Ying He; Qi Zou; Shanshan Li; Haodong Zhu; Ni Hong; Guoping Wang; Liping Wang (Archives of Virology, 2022)

Basin structure and multiresource potential based on high-precision airborne gravity and magnetic data - Yan-Xu Liu; Wen-Yong Li; An-Qi Cao; Shan Gao; Ning Wang; Li-Jie Wang; Cheng Yang (Applied Geophysics, 2022)

A Realistic and Integrated Model for Evaluating Offshore Oil Development - Rui Qiu; Zhuochao Li; Qin Zhang; Xin Yao; Shuyi Xie; Qi Liao; Bohong Wang (Journal of Marine Science and Engineering, 2022)
With the rising consumption of oil resources, major oil companies around the world have increasingly engaged in offshore oil exploration and development, and offshore oil resources have accounted for an increasing proportion. Offshore oil engineering projects are capital intensive, and the development of offshore oil fields faces a tough battle, especially in a period of low oil prices. Thus, a comprehensive evaluation model is highly needed to help assess economic benefits and provide meaningful and valuable information for operators and investors to make sensible decisions. This study firstly proposed a realistic and integrated evaluation model for offshore oil development based on actual historical project data. This evaluation model incorporated modules from the underwater system to the platform system and processes from oil reservoir extraction to oil, gas and water treatment. The uncertain parameters in the evaluation process are dealt with by sensitivity analysis and Monte Carlo simulation. The proposed model is applied to a typical offshore oil development project in Bohai Bay, China. The results reveal that the recovery factor and oil price have the greatest impact on the economic benefits. In the case of deterministic analysis, the breakeven oil price of the project is 40.59 USD/bbl. After considering the uncertainty of project parameters, the higher the oil price, the greater the probability of NPV > 0. When the oil price is higher than 70 USD/bbl, even with uncertain project parameters, the probability of NPV > 0 can still be as high as 97.39%.

Fast Multigrid Algorithm for Non-Linear Simulation of Intact and Damaged Ship Motions in Waves - Ziping Wang; Tingqiu Li; Qiu Jin; Hao Guo; Ji Zhao; Junlin Qi (Journal of Marine Science and Engineering, 2022)
This paper proposes a fast multigrid algorithm to simulate the non-linear motion of ships in both intact and damaged conditions. The simulations of ship motions in waves are known to require much time to calculate due to the strong non-linear interactions between ship and waves. To improve the calculation efficiency while retaining the accuracy, a prediction-correction strategy was designed to accelerate the simulation through three sets of locally refined meshes. The flow field was first estimated in a coarse mesh and then mapped to a locally refine mesh for further higher-fidelity corrections. A partitioned radial basis function (PRBF) method is proposed to interpolate and reconstruct the flow field for the refined mesh. A new two-phase flow solver was developed with a fast multigrid algorithm based on the Reynolds-averaged Navier–Stokes equations (RANSE). The new solver was applied to study the non-linear behavior of a damaged ship in beam waves and the effect of damaged compartments on ship rolling motion. Validation against the solution with the original method of single set meshes and experimental data indicates that the proposed algorithm yields satisfactory results while saving 30–40% of the computational time.

Sugar Product Diversification and Its Opportunities in China - Qi Wang; Cai-Feng Xie; Chang-Rong Shi; Yuan Li; Yu-Hao Shang; Chu-Xuan Hou; Fang-Xue Hang; Jian-Bin Li; Kai Li (Sugar Tech, 2022)

Dual-specificity Tyrosine Phosphorylation-regulated Kinase Inhibitor ID-8 Promotes Human Somatic Cell Reprogramming by Activating PDK4 Expression - Jinhong Xu; Shi Fang; Naweng Wang; Bo Li; Yongheng Huang; Qi Fan; Jingyi Shi; Huihui Liu; Zhicheng Shao (Stem Cell Reviews and Reports, 2022)

Intestinal Models for Personalized Medicine: from Conventional Models to Microfluidic Primary Intestine-on-a-chip - Xiang-Guang Li; Ming-xia Chen; Su-qing Zhao; Xiu-qi Wang (Stem Cell Reviews and Reports, 2022)

A preliminary study on the volcanic intrusive complex type beryllium metallogenic belt from the southeast coast of China - Can Rao; Rucheng Wang; Fuyuan Wu; Xudong Che; Xiaofeng Li; Qi Wang; Zhiqi Zhang; Runqiu Wu (Science China Earth Sciences, 2022)

Age-Related miRNA-Mediated Regulatory Networks Orchestrating Chronological Development of Meristems in Larix Kaempferi - Wan-Feng Li; Li-Wang Qi; Wen-Hua Yang (Journal of Plant Growth Regulation, 2022)
Plant growth and development is usually characterized by chronological age over the plants’ lifetimes. Age-related changes actually originate with meristems because they control if, where, when, and how new tissues are formed along the axis of the shoot. The “time-keeping” of plant meristem development is a complex process. To uncover the post-transcriptional regulation underlying the chronological development of Larix kaempferi (Japanese larch) meristems, we investigated the miRNA-mediated regulatory network in the defoliated, uppermost main stems of 1-, 2-, 5-, 10-, 25-, and 50-year-old L. kaempferi using RNA-seq methods. We identified 29 high-confidence miRNAs, three of which were defined, age-related miRNAs whose expression changed depending on L. kaempferi age, and 17 showed coordinated expression patterns with three age-related miRNAs based on hierarchical correlations. All hierarchically coordinated miRNAs and their targets constituted a miRNA-mediated regulatory network. The developmental timing pathway lka-miR-1-5p-156- SBP / SPL ( Squamosa Promoter Binding Protein-Like ), the lignin biosynthesis pathway lka-miR-7,13-5p-397- LAC ( Laccase ), and an unknown pathway lka-miR-3-5p- CMSS1 ( Cms1 Ribosomal Small Subunit Homolog ) were age-driven, and information from auxin and light could be integrated by the lka-miR-9-5p-390- TAS / ARF ( Trans-Acting siRNA3 /Auxin Response Factor) and lka-miR-8-5p- IRL4 (Plant Intracellular Ras-Group-Related LRR Protein 4 ) pathways, respectively. Age-driven regulatory network will lead the way to understand which and how genes mutually cross-regulate their activity orchestrating development of meristems of L. kaempferi with age. We also discussed and contributed to miRNA annotation and nomenclature.

Identification of microRNAs related with neural germ layer lineage-specific progenitors during reprogramming - Ruizhen Sun; Tiantian Gong; Hui Liu; Jingling Shen; Bin Wu; Qi Jiang; Qi Wang; Yue Zhang; Lian Duan; Jing Hu; Qiuming Li; Lei Lei; et al. (Journal of Molecular Histology, 2022)

CRIF1 promotes the progression of non-small-cell lung cancer by SIRT3- mediated deacetylation of PYCR1 - Qi Wang; Zhuolin Xie; Chang Li; Chun Xu; Cheng Ding; Sheng Ju; Jun Chen; Zihan Cui; Chen Chen; Biao Gu; Tengteng Wei; Jun Zhao (Journal of Molecular Histology, 2022)

The safety degree evaluation of marine biodiversity in China - Xiu-Mei Fu; Wan-Yu Wu; Fang Yang; Shan-Shan Jiang; Shi-Qi Wang; Xiao-Yan Li; Hui-Ying Tang; Ying Liu; Chang-Yun Wang (Journal of Coastal Conservation, 2022)

Contamination of 16 priority polycyclic aromatic hydrocarbons (PAHs) in urban source water at the tidal reach of the Yangtze River - Qi Dai; Yanyan Wang; Ling Chen; Pan Li; Shengji Xia; Qinghui Huang (Environmental Science and Pollution Research, 2022)

Mental health conditions and academic burnout among medical and non-medical undergraduates during the mitigation of COVID-19 pandemic in China - Qian Yang; Yueheng Liu; Winson Fuzun Yang; Pu Peng; Shubao Chen; Yunfei Wang; Xin Wang; Manyun Li; Yingying Wang; Yuzhu Hao; Li He; Qianjin Wang; et al. (Environmental Science and Pollution Research, 2022)
The outbreak of the novel coronavirus disease 2019 (COVID-19) has posed a great impact on people’s mental health, especially for undergraduate students. This study aimed to compare the mental health conditions and academic burnout between medical and non-medical undergraduates in China when the COVID-19 pandemic is mitigating. A cross-sectional online survey was conducted among 4,972 undergraduates between October 2020 and April 2021, when the pandemic was basically under control. The survey included basic demographics information and standardized scales to evaluate depression, anxiety, perceived stress, daytime sleepiness, alcohol abuse/dependence, quality of life, fatigue, and academic burnout. Compared with medical undergraduates, non-medical undergraduates had higher rates of moderate to severe depression symptoms (29.1% vs. 17.9%, P < 0.001), moderate to severe anxiety symptoms (19.7% vs. 8.9%, P < 0.001), alcohol abuse/dependence (16.3% vs.10.3%, P < 0.001), excessive daytime sleepiness (47.4% vs. 43.4%, P = 0.018), high perceived stress (34.7% vs. 22.2%, P < 0.001), high level of fatigue (51.8% vs. 42.2%, P < 0.001), low QOL (35.8% vs. 21.4%, P < 0.001), and higher academic burnout score (59.4 vs. 57.5, P < 0.001). Being non-medical undergraduates, depression, alcohol abuse/dependence, excessive daytime sleepiness, and high perceived stress were positively associated with academic burnout, while high QOL was negatively associated with the burnout (all P < 0.001). Excessive daytime sleepiness was the strongest predictor for academic burnout.

The preparation of slow-release fertilizers with biomass ash and water/waste acid solutions from desulfurization and denitrification of flue gas - Yongfeng Qi; Ziqian Wang; Panle Ge; Meiting Wang; Chuanling Zhang; Huawei Wang; Lingzhi Zhao; Jiang Wu; Yan Li (Environmental Science and Pollution Research, 2022)

Study on the operation performance and floc adhesion mechanism of dissolved air flotation equipment - Yonglei Wang; Huiyuan Ma; Xiaobo Wang; Ling Ju; Liping Tian; Hua Qi; Haiyang Yu; Guilin He; Jingjing Li (Environmental Science and Pollution Research, 2022)

Association between resting-state functional connectivity of amygdala subregions and peripheral pro-inflammation cytokines levels in bipolar disorder - Jiaying Gong; Guanmao Chen; Feng Chen; Shuming Zhong; Pan Chen; Hui Zhong; Shunkai Lai; Guixian Tang; Jurong Wang; Zhenye Luo; Zhangzhang Qi; Yanbin Jia; et al. (Brain Imaging and Behavior, 2022)

Nematicidal activity of volatile organic compounds produced by Bacillus altitudinis AMCC 1040 against Meloidogyne incognita - Lin Ye; Jian-Yu Wang; Xiao-Fang Liu; Qi Guan; Nong-Xiao Dou; Jian Li; Qian Zhang; Yan-Ming Gao; Min Wang; Jian-She Li; Bo Zhou (Archives of Microbiology, 2022)

Development of Solid-State Anaerobic Digestion and Aerobic Composting Hybrid Processes for Organic Solid Waste Treatment and Resource Recovery: a Review - Chuanren Qi; Rongrong Yin; Xingzu Gao; Jie Chen; Rui Wang; Zhicheng Xu; Wenhai Luo; Guoxue Li; Yangyang Li (Current Pollution Reports, 2022)

A neuropsin-based optogenetic tool for precise control of Gq signaling - Ruicheng Dai; Tao Yu; Danwei Weng; Heng Li; Yuting Cui; Zhaofa Wu; Qingchun Guo; Haiyue Zou; Wenting Wu; Xinwei Gao; Zhongyang Qi; Yuqi Ren; et al. (Science China Life Sciences, 2022)

Dogs lacking Apolipoprotein E show advanced atherosclerosis leading to apparent clinical complications - Hui Zhao; Jianping Zhao; Di Wu; Zhaolin Sun; Yang Hua; Min Zheng; Yumei Liu; Qi Yang; Xiahe Huang; Yuan Li; Yueshan Piao; Yingchun Wang; et al. (Science China Life Sciences, 2022)

Downregulation of CRTC1 Is Involved in CUMS-Induced Depression-Like Behavior in the Hippocampus and Its RNA Sequencing Analysis - Dezhu Li; Qi Liao; Yang Tao; Saiqi Ni; Chuang Wang; Dingli Xu; Dongsheng Zhou; Xingxing Li; Xinchun Jin; Xiaowei Chen; Wei Cui; Junfang Zhang (Molecular Neurobiology, 2022)

Beta-Boswellic Acid Protects Against Cerebral Ischemia/Reperfusion Injury via the Protein Kinase C Epsilon/Nuclear Factor Erythroid 2-like 2/Heme Oxygenase-1 Pathway - Mingming Wang; Jiaoyan Yu; Qi Yang; Chao Guo; Wei Zhang; Weiwei Li; Yan Weng; Yi Ding; Jingwen Wang (Molecular Neurobiology, 2022)

PPARγ Dysfunction in the Medial Prefrontal Cortex Mediates High-Fat Diet-Induced Depression - Cong-Cong Fu; Xin-Yi Zhang; Liu Xu; Hui-Xian Huang; Shuang Xu; Qiao-Qi Wu; Zhen Wang; Xi Gu; Li-Fang Lin; Song Lin; Ying-Ying Fang; Xiong Cao; et al. (Molecular Neurobiology, 2022)

Genetic testing enables a precision medicine approach for nephrolithiasis and nephrocalcinosis in pediatrics: a single-center cohort - Lin Huang; Chang Qi; Gaohong Zhu; Juanjuan Ding; Li Yuan; Jie Sun; Xuelian He; Xiaowen Wang (Molecular Genetics and Genomics, 2022)
Objective Hereditary factors are the main cause of pediatric nephrolithiasis (NL)/nephrocalcinosis (NC). We summarized the genotype–phenotype correlation of hereditary NL/NC in our center, to evaluate the role of genetic testing in early diagnosis. Methods The clinical data of 32 NL/NC cases, which were suspected to have an inherited basis, were retrospectively analyzed from May 2017 to August 2020. The trio-whole exome sequencing was used as the main approach for genetic testing, variants were confirmed by Sanger sequencing, and pathogenicity analysis according to protein function was predicted with custom-developed software. Results Causative monogenic mutations were detected in 24 of 32 NL/NC patients, and copy number variation was detected in one patient. A summary of manifestations in patients with inherited diseases revealed a significant degree of growth retardation, increased urinary excretion of the low-molecular weight protein, hypercalciuria, electrolyte imbalances, and young age of onset to be common in heredity disease. In addition, some patients had abnormal renal function (3 ppm 25). The most frequent pathology identified was distal renal tubular acidosis (with inclusion of SLC4A1 , ATP6V1B1 , and ATP6VOA4 genes), followed by Dent disease ( CLCN5 and OCRL1 genes), primary hyperoxaluria (PH) ( AGXT and HOGA1 genes) and Kabuki syndrome ( KMT2D gene), which was more likely to present as NC or recurrent stone and having a higher correlation with a specific biochemical phenotype and extrarenal phenotype. Conclusion The etiology of NL/NC is heterogeneous. This study explored in depth the relationship between phenotype and genotype in 32 patients, and confirmed that genetic testing and clinical phenotype evaluation enable the precision medicine approach to treating patients.

Piperock ichnofabrics from western Henan, China: spatial distribution pattern and environmental controls on middle Cambrian carbonates - Bingchen Liu; Da Li; Min Wang; Mingyue Dai; Wenyi He; Jingbo Li; Yong’an Qi (International Journal of Earth Sciences, 2022)

Removal of COD in wastewater by magnetic coagulant prepared from modified fly ash - Wen Wang; Liqiang Qi; Pan Zhang; Jichen Luo; Jingxin Li (Environmental Science and Pollution Research, 2022)

Increases in temperature response to CO2 emissions in biochar-amended vegetable field soil - Rong Huang; Zifang Wang; Yi Xiao; Luo Yu; Xuesong Gao; Changquan Wang; Bing Li; Qi Tao; Qiang Xu; Ming Gao (Environmental Science and Pollution Research, 2022)

Preparation of Iron Carbon Composite Material by Extracting Iron from Bauxite Residue and Its Adsorption of Heavy Metal Cd(II) - Xiaoli Lei; Zixuan Wang; Jiamin Qi; Xingyuan Wang; Yubao Chen; Bin Li; Yue Zhou (Bulletin of Environmental Contamination and Toxicology, 2022)

Cleaning Disposal of High-Iron Bauxite Residue Using Hydrothermal Hydrogen Reduction - Guotao Zhou; Yilin Wang; Tiangui Qi; Qiusheng Zhou; Guihua Liu; Zhihong Peng; Xiaobin Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Streptococcus vulneris sp. nov., isolated from wound of patient with diabetic foot ulcer (DFU) - Jen-hao Chung; Li-Ting Wang; Yi-Sheng Chen; Yun-Shien Lee; Shih-Ting Lin; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Jui-hsiang Li (Archives of Microbiology, 2022)

Stiripentol Enteric Solid Dispersion-Loaded Effervescent Tablets: Enhanced Dissolution, Stability, and Absorption - Ying Wang; Siyuan Xu; Ziyue Xiao; Yuxin Jiang; Qi Jiang; Jun Li; Wei He (AAPS PharmSciTech, 2022)

Glycosides from Buddleja officinalis with their protective effects on photoreceptor cells in light-damaged mouse retinas - Zehai Long; Xiaoye Du; Qiyao Wang; Zhijian Xu; Bo Li; Yong Zhang; Yu Chen; Qi Jia; Yiming Li; Weiliang Zhu (Natural Product Research, 2022)

Depletion of B7-H4 from C3H10 T1/2 Mesenchymal Stem Cells Attenuates their Immunomodulatory Therapy in Experimental Autoimmune Encephalomyelitis Mice - Hao Li; Simao Sun; Zhou Yin; Shugang Cao; Xiaopei Ji; Xiaoyu Duan; Hanqing Gao; Mingyuan Wang; Qi Fang; Wanli Dong; Xueguang Zhang; Yanzheng Gu; et al. (Neurotoxicity Research, 2022)

Diagnostic Performance of miR-485-3p in Patients with Parkinson’s Disease and its Relationship with Neuroinflammation - Xia Lin; Rui Wang; Ran Li; Taotao Tao; Danhong Zhang; Yuxiang Qi (NeuroMolecular Medicine, 2022)

Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat - Dong Peng; Han-Zi Qiao; Hong-Yu Tan; Yi-Xue Wang; Dan Luo; Li-Jun Qiao; Ye-Feng Cai; Shi-Jie Zhang; Qi Wang; Li Guan (Metabolic Brain Disease, 2022)

The interplay of particle properties and solution chemistry on aggregation kinetics of soil nanoparticles - Ning Hu; Chen-yang Xu; Zeng-chao Geng; Fei-nan Hu; Qi-rui Li; Ren-tian Ma; Qiang Wang (Journal of Soils and Sediments, 2022)

Effects of ridge-furrow rainwater-harvesting with biochar application on sediment control and alfalfa (Medicago sativa L.) fodder yield increase in semiarid regions of China - Wucheng Zhao; Erastus Mak-Mensah; Qi Wang; Xiaoyun Wang; Dengkui Zhang; Xujiao Zhou; Xiaole Zhao; Jin Chen; Qinglin Liu; Xiaoling Li (Journal of Soils and Sediments, 2022)

Application of galactinol to tomato enhances tolerance to cold and heat stresses - Yudong Liu; Li Zhang; Jian Ma; Sida Meng; Chunpeng Pang; Xiaomeng Zhao; Huidong Zhang; Shou Wang; Tao Xu; Yi He; Yufeng Liu; Mingfang Qi (Horticulture, Environment, and Biotechnology, 2022)

Localization of salt-tolerant QTL in rice germination stage under different salinity concentrations - Yanning Wang; Liping Chen; Guiting Song; Tao Huang; Guangliang Wu; Jingai Tan; Peng Wang; Qin Cheng; Caijing Li; Qi Zhong; Shiying Huang; Mengmeng Yang; et al. (Euphytica, 2022)

Kinetic study on degradation of micro-organics by different UV-based advanced oxidation processes in EfOM matrix - Donghai Yuan; Guangyu Liu; Fei Qi; Jinggang Wang; Yingying Kou; Yanqi Cui; Minghui Bai; Xinyu Li (Environmental Science and Pollution Research, 2022)

Durability and life prediction of fly ash geopolymer concrete in corrosion environments caused by dry and wet circulation - Qi Sun; Botao Li; Yiting Wang; Hui Wang (Environmental Science and Pollution Research, 2022)

Mercury removal from coal combustion flue gas by pyrite-modified fly ash adsorbent - Liqiang Qi; Xu Wang; Wen Wang; Jingxin Li; Yan Huang (Environmental Science and Pollution Research, 2022)

Performance and mechanism of the in situ restoration effect on VHCs in the polluted river water based on the orthogonal experiment: photosynthetic fluorescence characteristics and microbial community analysis - Jia Wang; Shuangrong Wu; Qi Yang; Yonggang Gu; Peijing Wang; Zhaoxin Li; Lei Li (Environmental Science and Pollution Research, 2022)

Considering economic-environmental joint benefits of water-land resources allocation for supporting sustainable agricultural system development in northeastern China - Yongyang Wang; Yulei Xie; Yanpeng Cai; Gengyuan Liu; Pan Zhang; Bowen Li; Bo Li; Qunpo Jia; Zixuan Qi; Jin Zhang (Environmental Science and Pollution Research, 2022)

A 3D Investigation of Geological Structure and Its Relationship to Mineralization in the Nanling-Xuancheng Ore District, Middle-Lower Yangtze River Metallogenic Belt, China - Sanming Lu; Xueyi Lan; Lili Zhao; Zanzan Zhang; Xiaoyong Yang; Zhuang Zhao; Dong Guo; Xiaochun Xu; Yongsheng Wang; Jianshe Li; Huasheng Qi (Journal of Earth Science, 2022)

Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells - Nan Huang; Yaxun Wei; Yi Cheng; Xiaolong Wang; Qi Wang; Dong Chen; Wenjing Li (Genes & Genomics, 2022)

The relationships between health risk and special weather conditions according to fungal community characteristics - Ting Zhang; Yao Wang; Jianhua Qi; Dahai Zhang; Xianguo Li (Aerobiologia, 2022)

Mycorrhizal fungi alleviate acidification‐induced phosphorus limitation: Evidence from a decade‐long field experiment of simulated acid deposition in a tropical forest in south China - Yuanliu Hu; Ji Chen; Dafeng Hui; Ying‐Ping Wang; Jianling Li; Jingwen Chen; Guoyin Chen; Yiren Zhu; Leiyi Zhang; Deqiang Zhang; Qi Deng (Global Change Biology, 2022)
South China has been experiencing very high rate of acid deposition and severe soil acidification in recent decades, which has been proposed to exacerbate the regional ecosystem phosphorus (P) limitation. We conducted a 10‐year field experiment of simulated acid deposition to examine how acidification impacts seasonal changes of different soil P fractions in a tropical forest with highly acidic soils in south China. As expected, acid addition significantly increased occluded P pool but reduced the other more labile P pools in the dry season. In the wet season, however, acid addition did not change microbial P, soluble P and labile organic P pools. Acid addition significantly increased exchangeable Al 3+ and Fe 3+ and the activation of Fe oxides in both seasons. Different from the decline of microbial abundance in the dry season, acid addition increased ectomycorrhizal fungi and its ratio to arbuscular mycorrhiza fungi in the wet season, which significantly stimulated phosphomonoesterase activities and likely promoted the dissolution of occluded P. Our results suggest that, even in already highly acidic soils, the acidification‐induced P limitation could be alleviated by stimulating ectomycorrhizal fungi and phosphomonoesterase activities. The differential responses and microbial controls of seasonal soil P transformation revealed here should be implemented into ecosystem biogeochemical model for predicting plant productivity under future acid deposition scenarios.

A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam - Yi-Fan Yu; Yue-Qian Li; Ru-Yue Wang; Xu Liu; Wen-Bo Cui; Xiao-Han Chen; Cheng-Mu Zhao; Feng-Ming Qi; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

A new NLR gene for resistance to Tomato spotted wilt virus in tomato (Solanum lycopersicum) - Shiming Qi; Yuanbo Shen; Xinyu Wang; Shijie Zhang; Yushun Li; Md. Monirul Islam; Jin Wang; Pan Zhao; Xiangqiang Zhan; Fei Zhang; Yan Liang (Theoretical and Applied Genetics, 2022)

Asymmetric changes of photosynthetically active radiation and light utilization efficiency during the maize growing season in North China - Huayun He; Qi Hu; Jing Wang; Mengyuan Xing; Yuanyuan Liu; Xiaochen Wang; Rong Li; Xuebiao Pan; Zhihua Pan; Binxiang Huang; Qijin He (Theoretical and Applied Climatology, 2022)

Kai-Xin-San Inhibits Tau Pathology and Neuronal Apoptosis in Aged SAMP8 Mice - Ya-Nan Jiao; Jing-Sheng Zhang; Wen-Jun Qiao; Shu-Yu Tian; Yi-Bin Wang; Chun-Yan Wang; Yan-Hui Zhang; Qi Zhang; Wen Li; Dong-Yu Min; Zhan-You Wang (Molecular Neurobiology, 2022)
Alzheimer’s disease (AD) is an age-related neurological disorder. Currently, there is no effective cure for AD due to its complexity in pathogenesis. In light of the complex pathogenesis of AD, the traditional Chinese medicine (TCM) formula Kai-Xin-San (KXS), which was used for amnesia treatment, has been proved to improve cognitive function in AD animal models. However, the active ingredients and the mechanism of KXS have not yet been clearly elucidated. In this study, network pharmacology analysis predicts that KXS yields 168 candidate compounds acting on 863 potential targets, 30 of which are associated with AD. Enrichment analysis revealed that the therapeutic mechanisms of KXS for AD are associated with the inhibition of Tau protein hyperphosphorylation, inflammation, and apoptosis. Therefore, we chose 7-month-old senescence-accelerated mouse prone 8 (SAMP8) mice as AD mouse model, which harbors the behavioral and pathological hallmarks of AD. Subsequently, the potential underlying action mechanisms of KXS on AD predicted by the network pharmacology analyses were experimentally validated in SAMP8 mice after intragastric administration of KXS for 3 months. We observed that KXS upregulated AKT phosphorylation, suppressed GSK3β and CDK5 activation, and inhibited the TLR4/MyD88/NF-κB signaling pathway to attenuate Tau hyperphosphorylation and neuroinflammation, thus suppressing neuronal apoptosis and improving the cognitive impairment of aged SAMP8 mice. Taken together, our findings reveal a multi-component and multi-target therapeutic mechanism of KXS for attenuating the progression of AD, contributing to the future development of TCM modernization, including KXS, and broader clinical application. Graphical abstract

Evaluating crop coefficient and associated processes in a drip irrigation with different color of biodegradable film mulching - Ning Chen; Xianyue Li; Haibin Shi; Qi Hu; Yuehong Zhang; Qin’ge Dong; Guoshuai Wang (Irrigation Science, 2022)

Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2 - Jinbao Zong; Yanping Zhang; Fenfen Guo; Changyuan Wang; Hong Li; Gaoyang Lin; Wenqing Jiang; Xiaoping Song; Xiufang Zhang; Feng Huang; Min Qi; Xin Zheng (Journal of Applied Genetics, 2022)

Assessment of heavy metals in surface water, sediment and macrozoobenthos in inland rivers: a case study of the Heihe River, Northwest China - Yu Wang; Bao-long Li; Jia-le Zhu; Qi Feng; Wei Liu; Yu-hua He; Xu Wang (Environmental Science and Pollution Research, 2022)

Application of slip line theory and core drilling in the prediction of rock c-φ parameters - Qi Wang; Bohong Liu; Bei Jiang; Hongke Gao; Shucai Li; Shuo Xu; Haojie Zhang (European Journal of Environmental and Civil Engineering, 2022)

Transcriptomic and metabolomic analysis reveals genes related to stress tolerance in high gravity brewing - Zhuofan Wu; Jinjing Wang; Chengtuo Niu; Chunfeng Liu; Feiyun Zheng; Qi Li (World Journal of Microbiology and Biotechnology, 2022)

Dissection of the practical soybean breeding pipeline by developing ZDX1, a high-throughput functional array - Rujian Sun; Bincheng Sun; Yu Tian; Shanshan Su; Yong Zhang; Wanhai Zhang; Jingshun Wang; Ping Yu; Bingfu Guo; Huihui Li; Yanfei Li; Huawei Gao; et al. (Theoretical and Applied Genetics, 2022)
Key message We developed the ZDX1 high-throughput functional soybean array for high accuracy evaluation and selection of both parents and progeny, which can greatly accelerate soybean breeding. Abstract Microarray technology facilitates rapid, accurate, and economical genotyping. Here, using resequencing data from 2214 representative soybean accessions, we developed the high-throughput functional array ZDX1, containing 158,959 SNPs, covering 90.92% of soybean genes and sites related to important traits. By application of the array, a total of 817 accessions were genotyped, including three subpopulations of candidate parental lines, parental lines and their progeny from practical breeding. The fixed SNPs were identified in progeny, indicating artificial selection during the breeding process. By identifying functional sites of target traits, novel soybean cyst nematode-resistant progeny and maturity-related novel sources were identified by allele combinations, demonstrating that functional sites provide an efficient method for the rapid screening of desirable traits or gene sources. Notably, we found that the breeding index (BI) was a good indicator for progeny selection. Superior progeny were derived from the combination of distantly related parents, with at least one parent having a higher BI. Furthermore, new combinations based on good performance were proposed for further breeding after excluding redundant and closely related parents. Genomic best linear unbiased prediction (GBLUP) analysis was the best analysis method and achieved the highest accuracy in predicting four traits when comparing SNPs in genic regions rather than whole genomic or intergenic SNPs. The prediction accuracy was improved by 32.1% by using progeny to expand the training population. Collectively, a versatile assay demonstrated that the functional ZDX1 array provided efficient information for the design and optimization of a breeding pipeline for accelerated soybean breeding.

QTL identification, fine mapping, and marker development for breeding peanut (Arachis hypogaea L.) resistant to bacterial wilt - Feiyan Qi; Ziqi Sun; Hua Liu; Zheng Zheng; Li Qin; Lei Shi; Qingzheng Chen; Haidong Liu; Xiufang Lin; Lijuan Miao; Mengdi Tian; Xiao Wang; et al. (Theoretical and Applied Genetics, 2022)
Key message A major QTL, qBWA12 , was fine mapped to a 216.68 kb physical region, and A12.4097252 was identified as a useful KASP marker for breeding peanut varieties resistant to bacterial wilt. Abstract Bacterial wilt, caused by Ralstonia solanacearum , is a major disease detrimental to peanut production in China. Breeding disease-resistant peanut varieties is the most economical and effective way to prevent the disease and yield loss. Fine mapping the QTLs for bacterial wilt resistance is critical for the marker-assisted breeding of disease-resistant varieties. A recombinant inbred population comprising 521 lines was used to construct a high-density genetic linkage map and to identify QTLs for bacterial wilt resistance following restriction-site-associated DNA sequencing. The genetic map, which included 5120 SNP markers, covered a length of 3179 cM with an average marker distance of 0.6 cM. Four QTLs for bacterial wilt resistance were mapped on four chromosomes. One major QTL, qBWA12 , with LOD score of 32.8–66.0 and PVE of 31.2–44.8%, was stably detected in all four development stages investigated over the 3 trial years. Additionally, qBWA12 spanned a 2.7 cM region, corresponding to approximately 0.4 Mb and was fine mapped to a 216.7 kb region by applying KASP markers that were polymorphic between the two parents based on whole-genome resequencing data. In a large collection of breeding and germplasm lines, it was proved that KASP marker A12.4097252 can be applied for the marker-assisted breeding to develop peanut varieties resistant to bacterial wilt. Of the 19 candidate genes in the region covered by qBWA12 , nine NBS-LRR genes should be further investigated regarding their potential contribution to the resistance of peanut against bacterial wilt.

Application of acid protease in the industrial production of corn ethanol - Liangliang Wang; Qi Yao; Jun Yue; Xirui Jiang; Fangfang Li (Systems Microbiology and Biomanufacturing, 2022)

Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China - Pengfei Cui; Xianying Zeng; Xuyong Li; Yanbing Li; Jianzhong Shi; Conghui Zhao; Zhiyuan Qu; Yanwen Wang; Jing Guo; Wenli Gu; Qi Ma; Yuancheng Zhang; et al. (Science China Life Sciences, 2022)
The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe, Russia, Middle East, and Asia since January 2020. To monitor the invasion and spread of the H5N8 virus in China, we performed active surveillance by analyzing 317 wild bird samples and swab samples collected from 41,172 poultry all over the country. We isolated 22 H5N8 viruses from wild birds and 14 H5N8 viruses from waterfowls. Genetic analysis indicated that the 36 viruses formed two different genotypes: one genotype viruses were widely detected from different wild birds and domestic waterfowls; the other genotype was isolated from a whopper swan. We further revealed the origin and spatiotemporal spread of these two distinct H5N8 virus genotypes in 2020 and 2021. Animal studies indicated that the H5N8 isolates are highly pathogenic to chickens, mildly pathogenic in ducks, but have distinct pathotypes in mice. Moreover, we found that vaccinated poultry in China could be completely protected against H5N8 virus challenge. Given that the H5N8 viruses are likely to continue to spread in wild birds, vaccination of poultry is highly recommended in high-risk countries to prevent H5N8 avian influenza.

Andrographolide Attenuates Blood–Brain Barrier Disruption, Neuronal Apoptosis, and Oxidative Stress Through Activation of Nrf2/HO-1 Signaling Pathway in Subarachnoid Hemorrhage - Pian Gong; Wei Zhang; Changlin Zou; Shoumeng Han; Qi Tian; Jianfeng Wang; Peibang He; Yujia Guo; Mingchang Li (Neurotoxicity Research, 2022)

Effects of dihydroartemisinin, a metabolite of artemisinin, on colon cancer chemoprevention and adaptive immune regulation - Chong-Zhi Wang; Chunping Wan; Yun Luo; Chun-Feng Zhang; Qi-Hui Zhang; Lina Chen; Zhi Liu; Daniel H. Wang; Mallory Lager; Cang-Hai Li; Ting-Liang Jiang; Lifei Hou; et al. (Molecular Biology Reports, 2022)

GSK-126 Protects CA1 Neurons from H3K27me3-Mediated Apoptosis in Cerebral Ischemia - Zhongcheng Wang; Yaxin Su; Lei Zhang; Ting Lan; Li Li; Suhua Qi (Molecular Neurobiology, 2022)
Epigenetics, including histone modifications, play a significant role in central nervous system diseases, but the underlying mechanism remains to be elucidated. The aim of this study was to evaluate the role of H3K27me3 in regulating transcriptomic and pathogenic mechanisms following global ischemic stroke. Here, we found that in vivo ischemic/reperfusion (I/R) injury induced marked upregulation of H3K27me3 in the hippocampus. The administration of GSK-126 to rat brains decreased the levels of H3K27me3 in the hippocampus and reduced neuronal apoptosis after experimental stroke. Furthermore, ChIP-seq data demonstrated that the primary role of GSK-126 in the ischemic brain is to reduce H3K27me3 enrichment, mediating negative regulation of the execution phase of apoptosis and the MAPK signaling pathway. Further study suggested that the protective role of GSK-126 in ischemic rats was antagonized by U0126, an inhibitor of ERK1/2. Collectively, we demonstrated the potential of H3K27me3 as a novel stroke therapeutic target, and GSK-126 exerted a neuroprotective function in ischemic brain injury, which might be associated with activation of the MAPK/ERK pathway. Graphical Abstract

New Target of Oxidative Stress Regulation in Cochleae: Alternative Splicing of the p62/Sqstm1 Gene - Pengjun Li; Dan Bing; Xiaodi Wang; Jin Chen; Zhihui Du; Yanbo Sun; Fan Qi; Hanqi Chu (Journal of Molecular Neuroscience, 2022)

Silence of MLK3 alleviates lipopolysaccharide-induced lung epithelial cell injury via inhibiting p53-mediated ferroptosis - Xiangjun Chen; Gangqiang Qi; Fang Fang; Yi Miao; Li Wang (Journal of Molecular Histology, 2022)

Effects of red/blue versus white LED light of different intensities on the growth and organic carbon and autotoxin secretion of hydroponic lettuce - Chengbo Zhou; Qi Wang; Wenke Liu; Baoshi Li; Mingjie Shao; Yubin Zhang (Horticulture, Environment, and Biotechnology, 2022)

The effect and attributable risk of daily temperature on category C infectious diarrhea in Guangdong Province, China - Qiang Hao; Qi Gao; Ran Zhao; Haitao Wang; Hao Li; Baofa Jiang (Environmental Science and Pollution Research, 2022)

AT1 Receptors: Their Actions from Hypertension to Cognitive Impairment - Hanxue Wu; Qi Sun; Shenglan Yuan; Jiawei Wang; Fanni Li; Hongli Gao; Xingjuan Chen; Rui Yang; Jiaxi Xu (Cardiovascular Toxicology, 2022)

Development of a Label-Free Colorimetric Aptasensor with Rationally Utilized Aptamer for Rapid Detection of Okadaic Acid - Xiaochen Yan; Xiaoyan Qi; Yinglin Zhao; Ling Li; Rui Ma; Lele Wang; Sai Wang; Xiangzhao Mao (Journal of Ocean University of China, 2022)

Genetic Stock Identification and Adaptability of Hatchery-Reared Black Rockfish, Sebastes schlegelii, Released Into the North Yellow Sea waters - Qi Liu; Ziwei Wang; Weiyuan Li; Qi Zhang; Binwei Liu; Meiyuan Li; Ying Liu; Tao Tian; Hongwei Yan (Frontiers in Marine Science, 2022)
Successful stock enhancement refers to the maintenance of economic profit, whilst minimizing negative genetic and ecological effects. As hatchery environments differ from natural habitats, post-release identification of hatchery-reared juveniles, and estimation of their adaptability are essential steps in conducting responsible stock enhancement. The black rockfish is an important fishery species in Japan, South Korea and China. Overfishing has dramatically decreased natural resources and a stock enhancement program was first initiated in the Liaodong peninsula in 2019. We traced this program and used nine microsatellite markers to identify 279 individuals as being hatchery-reared, out of 710 captured fish, with a resource contribution rate of 39.30%. These results indicated that stock enhancement of this species is likely to maintain a positive economic performance. To understand the potential genetic impacts on the local wild population, the genetic patterns of S. schlegelii stocks (wild controls from 2017, wild controls from 2018, female broodstock from 2019, recaptured hatchery-reared fish from 2019 and recaptured non-hatchery-reared fish from 2019 stocks) from the same habitat were evaluated before and after artificial stocking. We found that the S. schlegelii population was able to maintain high genetic diversity and showed weak genetic differentiation, but potential genetic introgression derived from stock enhancement should be concerned. The hatchery-reared individuals showed good adaptability, as shown by feeding condition and growth status. There was no obvious morphology difference between hatchery-reared fish and their wild counterparts, but hatchery-reared fish seemed to be bigger in size (significantly higher in MDB and BW), had a larger head (significantly larger in PRL/HL and ID/HL) and smaller paired fins (significantly smaller PCFL/BL), when compared with wild individuals across all investigation months. Our results provided insights into management of black rockfish enhancement in the future.

Dynamic Analysis of Monopile-Type Offshore Wind Turbine Under Sea Ice Coupling With Fluid-Structure Interaction - Yingzhou Liu; Wei Shi; Wenhua Wang; Xin Li; Shengwenjun Qi; Bin Wang (Frontiers in Marine Science, 2022)
The interaction between vertical offshore wind turbine (OWT) and sea ice with fluid is a complex process including local and global crushing of ice fragments and vibration of OWT. It is crucial to study the ice resistance of OWT structures considering the fluid-structure interaction (FSI). This article investigates a complete process of dynamic sea ice-monopile OWT interaction considering soil-structure interaction (SSI) and FSI effects. A fully coupled dynamic collision model of sea ice and OWT incorporating with the explicit non-linear collision tool ANSYS/LS-DYNA is proposed. The simulated ice loads in this study is verified by different simulation methods and international static ice force standards closely related to ice dynamic characteristic parameters. Then, the dynamic response and damage of the OWT structure during ice-structure interaction are studied using the fully interaction model with FSI coupling. The simulated ice force can produce a significant vibration response in the structure coupling with FSI due to occurrence of ice-induced resonance in the ice velocity range of 2.5–3.5 cm/s. Finally, the effect of fluid on the sea ice-OWT interaction in the initial velocity collision of sea ice is analyzed. FSI coupling can cause a certain level of collision hysteresis, accelerate the failure of sea ice breaking and reasonably reduce the energy of the structure.

New treatment for amblyopia based on rules of synaptic plasticity: a randomized clinical trial - Xin Huang; Huika Xia; Qi Zhang; Colin Blakemore; Yan Nan; Wenyao Wang; Jie Gao; Spencer S. Ng; Jing Wen; Tiejun Huang; Xiaoqing Li; Mingliang Pu (Science China Life Sciences, 2022)

Screening and identification of HLA-A2-restricted neoepitopes for immunotherapy of non-microsatellite instability-high colorectal cancer - Ranran Shi; Yubing Li; Ling Ran; Yu Dong; Xiuman Zhou; Jingwen Tang; Lu Han; Mingshuang Wang; Liwei Pang; Yuanming Qi; Yahong Wu; Yanfeng Gao (Science China Life Sciences, 2022)

Characterization of Photorhabdus Virulence Cassette as a causative agent in the emerging pathogen Photorhabdus asymbiotica - Xia Wang; Jiaxuan Cheng; Jiawei Shen; Liguo Liu; Ningning Li; Ning Gao; Feng Jiang; Qi Jin (Science China Life Sciences, 2022)

Spatially explicit reconstruction of the population distribution in the Tuojiang River Basin during 1911–2010 using random forest regression - Qi Wang; Xuesong Gao; Qiquan Li; Ting Lan; Rong Huang; Ouping Deng (Regional Environmental Change, 2022)

The branch-thorn occurrence of Lycium ruthenicum is associated with leaf DNA hypermethylation in response to soil water content - Ailin Yang; Xinyu Qi; Qin-Mei Wang; Hao Wang; Yucheng Wang; Lujia Li; Wen Liu; Yang Qiao (Molecular Biology Reports, 2022)

Alternation of stromatolites and vertical burrows controlled by storm processes and sea-level changes in the middle Cambrian carbonates of central China - Bingchen Liu; Mingyue Dai; Yong’an Qi; Xiaofang Sun; Wei Zheng; Min Wang; Zhifeng Xing; Da Li; Yuchao Fan (Journal of Earth System Science, 2022)

Recycling of supra-crustal materials in the rhyolites from north Sonid Youqi: implications for the crustal evolution in the southeast Central Asian Orogenic Belt - Jian-Zhou Tang; Zhicheng Zhang; Bo Liu; Shaohua Zhang; Ke Li; Qi Wang; Cong Ding (International Journal of Earth Sciences, 2022)

Circular RNA circ_0008934 promotes hepatocellular carcinoma growth and metastasis through modulating miR-1305/TMTC3 axis - Jia-Xi Li; Jin-Jiang Wang; Zhou-Feng Deng; Hao Zheng; Chun-Mei Yang; Ying Yuan; Cheng Yang; Fang-Fang Gu; Wei-Qi Wu; Guang-Lei Qiao; Li-Jun Ma (Human Cell, 2022)

Land development suitability analysis for transport planning evaluation and optimization in mountainous ecological region - Gao-ru Zhu; Man Wang; Qi-li Li; Jie Liu; Yan-ni Zhao; Jia-wei Gao; Hong-lei Xu (Journal of Mountain Science, 2022)

Morphological and Molecular Characterization of Paragonimus skrjabini Complex from Yunnan, China: A Brief Report - Qiu-Hong Shu; Shu-De Li; Ming Tian; Yong Meng; Shu-Mei-Qi He; Min Zhu; Miao-Miao Wang; Wen-Lin Wang (Acta Parasitologica, 2022)
Purpose To perform environmental sampling and molecular identification of Paragonimus in endemic regions, which may help in minimizing transmission among humans. Methods Mountain crabs from the genus Potamiscus were collected and the encysted metacercariae were extracted and subjected to morphological identification, followed by animal inoculation in Sprague–Dawley (SD) rats. After 112 days of infection, animals were killed and adult worms were extracted from lungs and muscles. The morphology of adult worms was characterized by microscopy and molecular identification was done by polymerase chain reaction, followed by sequencing of cox1 and ITS2 genes. Phylogenetic analysis was done by maximum parsimony method. Results A total of 447 crabs were captured from the streams of Tongchang Town, Jinping County, Yunnan Province, China. The infection rate was found to be 41% (186 out of 447 crabs). The metacercariae of Paragonimus skrjabini was identified by the characteristics round or spherical encysted form measuring 410 to 460 × 400 to 460 µm. After animal infection in SD rats, adults were presumptively confirmed to be P. skrjabini , which was also confirmed by gene amplification and sequence analysis of cox1 and ITS2 regions. Paragonimus skrjabini clustered with previously reported P. skrjabini from Yunnan and Vietnam. The confidence values of their branches were > 95%. Phylogenetic analysis of the ITS2 region revealed two distinct clusters with distinct geographical grouping. Phylogenetic analysis with the combined data sets reiterated the geographical grouping with P. skrjabini from Yunnan clustering with strains from Vietnam. Conclusion Metacercariae of P. skrjabini was discovered in freshwater crabs in Yunnan province, China, and the strains were phylogenetically related to P. skrjabini from Vietnam.

A New Scheme for Capturing Global Conditional Nonlinear Optimal Perturbation - Siyuan Liu; Qi Shao; Wei Li; Guijun Han; Kangzhuang Liang; Yantian Gong; Ru Wang; Hanyu Liu; Song Hu (Journal of Marine Science and Engineering, 2022)
Conditional nonlinear optimal perturbation (CNOP) represents the initial perturbation that satisfies a certain physical constraint condition, and leads to a maximum prediction error at the moment of prediction. The CNOP method is a useful tool in studying atmosphere and ocean predictability problems. Generally, the optimization algorithm based on the gradient of the cost function to compute CNOP requires an initial guess. The traditional scheme randomly chooses the initial guess of CNOP within the constraint range and therefore this scheme is called RIG-CNOP. However, the RIG-CNOP scheme reduces the probability of capturing the global CNOP in many cases, such as the prediction model is strongly nonlinear or long-term prediction is performed, or multiple extreme values existed in the cost function. Considering the limitations of the RIG-CNOP scheme, we propose a new initial guess selection scheme. In this scheme, we first pre-analyze a series of random initial guesses, and then, an optimal initial guess is selected. The above process replaces the initial guess selection scheme in the traditional scheme, which is called PAIG-CNOP. Numerical experiments are conducted utilizing the Lorenz-63 model. Also, to compare the performance of the PAIG-CNOP method with the RIG-CNOP method in capturing global CNOP, the CNOP and the maximum cost function value (MCFV) obtained by the filtering method (FM) are used as benchmarks (this value is called FMMCFV in brief). The experimental results show that even the prediction model is strongly nonlinear or the prediction time is long, or the cost function has multiple extreme values, the PAIG-CNOP method can capture the global CNOP with a high probability. The results show that the PAIG-CNOP method has a higher probability of capturing the global CNOP than the RIG-CNOP method. In addition, we use an ensemble-based technique in the computation of gradients, thus avoiding the use of adjoint techniques in the maximization process. Due to the attractive features of the new method, the PAIG-CNOP method is an efficient and useful method for solving CNOP, it can be more easily applied to obtain the global CNOP of operational prediction models.

Ecdysis Triggering Hormone, Eclosion Hormone, and Crustacean Cardioactive Peptide Play Essential but Different Roles in the Molting Process of Mud Crab, Scylla paramamosain - Yan-Fei Zhao; Qi-Qiao Wen; Chun-Mei Ao; Wei Wang; Li-Li Shi; Cheng-Gui Wang; Siuming-Francis Chan (Frontiers in Marine Science, 2022)
Molting behavior in insects is controlled by the ecdysis triggering hormone (ETH), eclosion hormone (EH) and the crustacean cardioactive peptide (CCAP). At present, the regulation of molting behavior in crustaceans remains unclear. Here, we studied the roles of ETH , EH , and CCAP in the molt regulation of the crab, Scylla paramamosain from their expression pattern and in vivo assays. The results showed that transcripts of ETH , EH , and CCAP were mainly localized in thoracic ganglia and fluctuated periodically with the molting cycle. When ETH or CCAP was knockdown at early premolt stage (D0), molting of crabs was interrupted and all animals died at late premolt stage (D2). While the EH gene was knock-down, most crabs were dead before D2. Injection of synthetic peptide for ETH or CCAP rescued ETH - or CCAP -gene knock-down crabs separately. However, none of peptides could rescue dsEH -injected crabs. At D0 stage, knockdown of ETH down-regulated the transcriptions of EH and CCAP ; while ETH was up-regulated when EH was knockdown. At D2 stage, ETH transcripts levels were reduced with the injection of dsEH but increased with the same dose of dsETH as crabs at D0 stage. Co-injection of ds ETH and ds EH down-regulated ETH at D2 stage. Results showed that ETH , EH , and CCAP play essential but different roles in molt regulation in mud crab. In summary, the result of this study contributes to the discovery of different molecular mechanisms between Insecta and Crustacea and may provide insight to develop fishery drugs that helps aquacultured crustaceans to molt successfully.

Combined Effects of Microplastics and Benzo[a]pyrene on the Marine Diatom Chaetoceros muelleri - Yuanyuan Su; Huaiyuan Qi; Yipeng Hou; Mengyi Gao; Jie Li; Minggang Cai; Xiaoshan Zhu; Miao Chen; Chengjun Ge; Dongdong Fu; Zezheng Wang; Licheng Peng (Frontiers in Marine Science, 2022)
Microplastics are regarded as ubiquitous pollutants in the ocean and have attracted worldwide concerns. Benzo[a]pyrene (B[a]P), one of typical polycyclic aromatic hydrocarbons (PAHs), is commonly detected in marine environment. Once coexisted, the microplastics and B[a]P may interact with each other and result in combined toxicity to organisms, and these remain to be systematically elucidated. Thus, this study aims to investigate (i) the effects of single micro-sized polystyrene (mPS), polyethylene terephthalate (mPET), and B[a]P on cell growth of Chaetoceros muelleri ; and (ii) the interaction of microplastics and B[a]P, and their combined effects on C. muelleri . The results showed that both single microplastics and B[a]P at a high concentration of 150 μg/L inhibited the growth of C. muelleri . For single treatment of microplastics, stronger inhibition effects on microalgae was caused by mPET than that of mPS, with the highest IR of 25.23 and 11.17%, respectively. This may be attributed to the obvious surface roughness of mPET. By comparison, the combined effects of microplastics and B[a]P significantly inhibited the growth of C. muelleri as compared with the single treatment of B[a]P ( P < 0.05). Synergistic effect was found in the combination of microplastics with B[a]P at high concentrations of 150 μg/L. Interestingly, the antagonistic effect on C. muelleri was observed in the combined treatment of microplastics and B[a]P at low concentrations of 10 μg/L. In addition, the pollutants reduced the content of photosynthetic pigments in microalgal cells. The SOD and MDA content of microalgae increased in the early stage of exposure to pollutants (e.g., Days 1 and 5), but decreased in the later stage (Day 15) compared with the control group. The decreased superoxide dismutase (SOD) and catalase (CAT) activity in single and composite systems may indicate that the antioxidative enzymatic system of microalgae has been inhibited or destroyed. This study will be helpful to further explore the ecological threats of microplastics and PAHs to the marine ecosystem.

Two new diterpenoids from Penicillium chrysogenum MT-12, an endophytic fungus isolated from Huperzia serrata - Bowen Qi; Fangfang Jia; Yuan Luo; Ning Ding; Sainan Li; Fanyu Shi; Yan Hai; Lili Wang; Zhi-Xiang Zhu; Xiao Liu; Pengfei Tu; She-Po Shi (Natural Product Research, 2022)

Biological control of postharvest fungal decays in citrus: a review - Zhenshuo Wang; Yuan Sui; Jishun Li; Xiaoli Tian; Qi Wang (Critical Reviews in Food Science and Nutrition, 2022)

Characterization and fine mapping of a lesion mimic mutant (Lm5) with enhanced stripe rust and powdery mildew resistance in bread wheat (Triticum aestivum L.) - Cong Li; Hang Liu; Jian Wang; Qi Pan; Yue Wang; Kunyan Wu; Peiying Jia; Yang Mu; Huaping Tang; Qiang Xu; Qiantao Jiang; Yaxi Liu; et al. (Theoretical and Applied Genetics, 2022)

Delineating the Decussating Dentato-rubro-thalamic Tract and Its Connections in Humans Using Diffusion Spectrum Imaging Techniques - Si-Qi Ou; Peng-Hu Wei; Xiao-Tong Fan; Yi-He Wang; Fei Meng; Mu-Yang Li; Yong-Zhi Shan; Guo-Guang Zhao (The Cerebellum, 2022)

Prevalence and molecular epidemiology of equine piroplasmosis in China: a neglected tick-borne disease - Kewei Chen; Zhe Hu; Jingkun Li; Jingfei Wang; Diqiu Liu; Ting Qi; Wei Guo; Cheng Du; Xiaojun Wang (Science China Life Sciences, 2022)

Short-form OPA1 is a molecular chaperone in mitochondrial intermembrane space - Deyang Yao; Yukun Li; Sheng Zeng; Zhifan Li; Zahir Shah; Bigui Song; Jinglei Liu; Yi Wu; Liang Yang; Qi Long; Wenqian Wang; Zhijuan Hu; et al. (Science China Life Sciences, 2022)

Cellular metabolic basis of altered immunity in the lungs of patients with COVID-19 - Shuangyan Li; Fuxiaonan Zhao; Jing Ye; Kuan Li; Qi Wang; Zhongchao Du; Qing Yue; Sisi Wang; Qi Wu; Huaiyong Chen (Medical Microbiology and Immunology, 2022)

Lighting for work: a study on the effect of underground low-light environment on miners’ physiology - Jing Li; Yaru Qin; Cheng Guan; Yanli Xin; Zhen Wang; Ruikang Qi (Environmental Science and Pollution Research, 2022)

Toxicity and behavioral response of zebrafish exposed to combined microplastic and bisphenol analogues - Xiyan Mu; Suzhen Qi; Jia Liu; Lilai Yuan; Ying Huang; Jiaying Xue; Le Qian; Chengju Wang; Yingren Li (Environmental Chemistry Letters, 2022)

Does income inequality aggravate the impacts of air pollution on physical health? Evidence from China - Zhiming Yang; Zhen Wang; Xiao-Chen Yuan; Yu Qi; Yunquan Zhang; Weiqing Wang; Fanglin He; Jing Li (Environment, Development and Sustainability, 2022)

Developing a highly efficient regeneration system for leaves of tissue-cultured tetraploid Robinia pseudoacacia L. - Xiuyu Li; Qi Guo; Chao Han; Juan Li; Li Dong; Sen Cao; Zijie Zhang; Yuhan Sun; Ruohan Wang; Yun Li (In Vitro Cellular & Developmental Biology - Plant, 2022)

Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function - Huijie Zhang; Jiawei Qin; Xinqiang Lan; Weirong Zeng; Jing Zhou; Tian-E Huang; Wan-Li Xiao; Qi-Quan Wang; Sujiao Sun; Weiting Su; Wenhui Nie; Shan Yang; et al. (Biogerontology, 2022)

Effect of tree form on wheat yield via changing microenvironment in almond–wheat intercropping - Wen Zhang; Hui Xie; Shou-An Han; Min Wang; Ming-Qi Pan; Xu Qiao; Long Li (Agroforestry Systems, 2022)

Ethylene insensitive mutation alleviates cadmium-induced photosynthesis impairment in Arabidopsis plants - Qi-Yu Zhao; Chun-Xiu Gu; Yu Wang; Guang-Zhe Li; Lin Hao (Acta Physiologiae Plantarum, 2022)

Two new threonine-containing metabolites from fungus Curvularia inaequalis strain HS-FG-257 - Shao-Yong Zhang; Jian-Song Li; Hui Zhang; Huan Qi; Rui-Jun Wang; Chou-Fei Wu; Li-Qin Zhang; An-Liang Chen; Ji-Dong Wang; Zhi-Kui Hao (Natural Product Research, 2022)

Four new indole alkaloids from the roots of Isatis tinctoria - Dongdong Zhang; Yu Sun; Yanhong Shi; Ximin Wu; Qi Jia; Kaixian Chen; Yiming Li; Rui Wang (Natural Product Research, 2022)

The Effect of Frying Process on Lipids in Small Yellow Croaker ( Larimichthys polyactis ) and Frying Oil - Shi-Miao Wang; Jian Li; Qi Zhao; Dan-Dan Lv; Kanyasiri Rakariyatham (Journal of Aquatic Food Product Technology, 2022)