Prelimbic proBDNF Facilitates Retrieval-Dependent Fear Memory Destabilization by Regulation of Synaptic and Neural Functions in Juvenile Rats - Wei Sun; Xiao Chen; Yazi Mei; Yang Yang; Xiaoliang Li; Lei An (Molecular Neurobiology, 2022)

Altered life history traits and transcripts of molting- and reproduction-related genes by cadmium in Daphnia magna - Xinrong Wei; Xiao Li; Hongsong Liu; Haojun Lei; Weijun Sun; Dan Li; Wu Dong; Hongxing Chen; Lingtian Xie (Ecotoxicology, 2022)

Migration of Alkaline Constituents and Restoration Evaluation in Bauxite Residue Disposal Areas - Yiwei Li; Qihou Li; Wei Sun; Zhihong Peng; Graeme J. Millar; Shengguo Xue; Jun Jiang (Bulletin of Environmental Contamination and Toxicology, 2022)

Trophic Diversity and Food Web Structure of Vegetated Habitats Along a Coastal Topographic Gradient - Xiaoxiao Li; Wei Yang; Tao Sun; Zhifeng Yang (Frontiers in Marine Science, 2022)
Land–sea interactions in coastal wetlands create heterogeneous vegetated habitats with regular zonation along a topographic gradient. However, it’s unclear how the trophic diversity of communities and trophic structure of food webs change along the gradient. Here, we investigated the empirically resolved food web structure and trophic diversity across four vegetated habitats ( Phragmites australis , Suaeda salsa , Spartina alterniflora , and Zostera japonica seagrass) along a gradient from upland to near-shore waters in the Yellow River Delta wetland. We quantified δ 13 C and δ 15 N of carbon sources (detritus, primary producers) and consumers (zooplankton, macroinvertebrates, fish). δ 13 C and δ 15 N of the carbon sources and consumers differed significantly among the four habitats. Carbon sources and consumers became more 13 C-enriched and 15 N-enriched along the gradient, respectively. The consumer trophic position was higher in the S. salsa habitat than in the seagrass habitat, followed by the S. alterniflora and P. australis habitats. The habitat formed by invasive S. alterniflora had the lowest corrected standard ellipse areas in the δ 13 C vs. δ 15 N plots for the basal carbon sources and all consumers combined, and the lowest Layman community metrics for the δ 13 C range, total area, and centroid distance; thus, trophic groups in this habitat had the lowest isotopic trophic diversity. Using a Bayesian isotope mixing model, we found that consumer diet compositions differed greatly among the habitats where the consumer was present, except for shrimps and polychaetes. Food web topological properties (species richness, number of trophic links, linkage density, proportions of intermediate consumers and omnivores) increased along the gradient. Generally, habitat heterogeneity created highly variable food webs. Our results provide insights into the spatial variation in coastal ecosystems along a topographic gradient, and demonstrate the need to protect habitat heterogeneity in coastal wetlands, combined with adaptive management to control invasive species.

Response of Size-Fractionated Chlorophyll a to Upwelling and Kuroshio in Northeastern South China Sea - Danyang Li; Shuang Yang; Yuqiu Wei; Xingzhou Wang; Yingjie Mao; Congcong Guo; Jun Sun (Journal of Marine Science and Engineering, 2022)
The variability of size-fractionated chlorophyll a (Chl a) biomass and related environmental variables was investigated in a survey conducted in the northeastern South China Sea (NESCS), to assess their responses to upwelling, Kuroshio, and nutrients in the summer of 2017. The depth-weighted total Chl a concentration varied from 0.057 to 0.496 μg/L. The contribution of size-fractionated Chl a to total Chl a biomass was determined, with the contributions of pico-Chl a (0.2–2 μm), nano-Chl a (2–20 μm), and micro-Chl a (>20 μm) found to be 52.87%, 38.54%, and 8.59%, respectively. We found that nano-Chl a contributes more to total-Chl a than pico-Chl a in areas affected by upwelling. In addition, the results indicated an upward shift in the deep chlorophyll maximum (DCM) content in the upwelling area and the Kuroshio intrusion area. The Chl a biomass was increased in the physical process. Overall, correlation analysis showed that environmental variables (temperature, salinity, phosphate, silicate, nitrate, nitrite, ammonium) significantly influenced the phytoplankton biomass. However, physical processes determined the changes in environmental variables, with upwelling and Kuroshio being the main factors regulating the distribution of Chl a.

Decomposition and Nutrient Release into Water from Litter Mixtures of Coastal Wetland Species - Patrick Ndayambaje; Tingfeng Zhang; Lili Wei; Lin Liu; Xu Huang; Jie Li; Shaohua Tian; Yu Xin; Xuecong Sun; Chaoxiang Liu (Wetlands, 2022)

Sandstorms cause shrinkage of Haloxylon ammodendron shrubs and limit their self-renewal - Sheng-bo Shi; Dang-wei Zhou; Fang-lin Wang; Rui Shi; Tao Sun; Tian-cai Li; Jia-lin Ma; Xiang Wan; Jian-ping Ma; Jing-nian Tang (Theoretical and Experimental Plant Physiology, 2022)
Haloxylon ammodendron is an excellent windproof and sand-fixing species whose shrubs are widely cultivated in arid desert areas of northwest China but are now at risk of degradation and shrinkage. Using the chlorophyll fluorescence image analysis technique, the response of photosystem II (PSII) photochemical efficiency and non-photochemical quenching capacity to sediment-carrying wind and sand-free wind (both 12 m s −1 ) lasting for 10, 20, and 40 min were studied with seedlings in a wind tunnel. The results indicated that the sand-free wind had little influence on the maximum quantum efficiency of PSII photochemistry, F v / F m , which was approximately 0.80 on average; however, the F v / F m decreased over exposure time in the sediment-carrying wind group, with values smaller than those in the wind-only group. The non-photochemical quenching was sensitive to wind erosion, and sediment-carrying wind could aggravate the reduction in non-photochemical quenching ( NPQ ). Except for the 10 min duration, the maximum quantum efficiency of PSII photochemistry after dark recovery for 15 min, F v r / F m r , was lower in seedlings exposed to sediment-carrying wind than in those in the wind-only group. Compared to wind-only, wind-blown sand led to a water imbalance and withering in seedlings, causing the concentration of photosynthetic pigments (when based on the fresh mass of green branches) to not decrease. With a longer exposure time to sediment-carrying wind, both the probability and extent of lignified spots occurring increased in green assimilative branches. Our results demonstrated that sediment-carrying wind at 12 m s −1 lasting for 20 min or more could cause irreversible damage to the photosynthetic apparatus of H. ammodendron seedlings. Therefore, frequent and strong sandstorms are the main disturbance factors leading to shrinkage of shrubs and limiting their self-renewal.

Correction to: Sox10 Gene Is Required for the Survival of Saccular and Utricular Hair Cells in a Porcine Model - Jing-cui Qi; Qing-qing Jiang; Long Ma; Shuo-long Yuan; Wei Sun; Li-sheng Yu; Wei-wei Guo; Shi-ming Yang (Molecular Neurobiology, 2022)

GLP-1R Agonist Exendin-4 Protects Against Hemorrhagic Transformation Induced by rtPA After Ischemic Stroke via the Wnt/β-Catenin Signaling Pathway - Chengli Liu; Shanshan Sun; Jie Xie; Hui Li; Tianyu Li; Qiqi Wu; Yongsheng Zhang; Xiangjun Bai; Jian Wang; Xin Wang; Zhanfei Li; Wei Wang (Molecular Neurobiology, 2022)
Tissue plasminogen activator (tPA) is recommended by the FDA to dissolve intravascular clots after acute ischemic stroke (AIS). However, it may contribute to hemorrhagic transformation (HT). The Wnt/β-catenin signaling pathway plays an important role in regulating the blood–brain barrier (BBB) formation in the central nervous system. We explored whether glucagon-like peptide-1 receptor (GLP-1R) agonist exendin-4 (EX-4) reduces the risk of HT after rtPA treatment via the Wnt/β-catenin pathway by using a rat transient middle cerebral artery occlusion (MCAO) model in vivo and an oxygen–glucose deprivation plus reoxygenation (OGD/R) model in vitro. Our results showed that EX-4 attenuated neurological deficits, brain edema, infarct volume, BBB disruption, and rtPA-induced HT in ischemic stroke. EX-4 suppressed the production of ROS and the activation of MMP-9 to protect the integrity of the BBB by activating the Wnt/β-catenin signaling pathway. PRI-724, a selective inhibitor of β-catenin, was able to reverse the therapeutic effect of EX-4 in vivo and in vitro. Therefore, our results indicate that the GLP-1R agonist may be a potential therapeutic agent to decrease the risk of rtPA-induced HT after ischemic stroke via the Wnt/β-catenin signaling pathway.

Sox10 Gene Is Required for the Survival of Saccular and Utricular Hair Cells in a Porcine Model - Jing-cui Qi; Qing-qing Jiang; Long Ma; Shuo-long Yuan; Wei Sun; Li-sheng Yu; Wei-wei Guo; Shi-ming Yang (Molecular Neurobiology, 2022)

Application of enzymatic hydrolysate of Ulva clathrata as biostimulant improved physiological and metabolic adaptation to salt-alkaline stress in wheat - Feiyu Li; Zhihua Wu; Siqi Zuo; Li Fan; Zhengpeng Wei; Ling Ma; Wenke Sun; Chunying Du; Ruizhi Liu; Peng Wang (Journal of Applied Phycology, 2022)

Geological risks and countermeasures for mountain tunneling through a large karst cave in Southwest Hubei, China: a case study - Yan-Wei Li; Qing-Long Cui; Qiang Wu; Jie Sun (Arabian Journal of Geosciences, 2022)

Ambra1 regulates apoptosis and chemosensitivity in breast cancer cells through the Akt-FoxO1-Bim pathway - Wei-liang Sun; Ling-yan He; Li Liang; Si-yu Liu; Jie Luo; Mei-ling Lv; Zheng-wen Cai (Apoptosis, 2022)

Understanding the Sources of Heavy Metal Pollution in Ambient Air of Neighboring a Solid Waste Landfill Site - Umangi H. Mehta; Daya S. Kaul; Dane Westerdahl; Zhi Ning; Kai Zhang; Li Sun; Peng Wei; Hardik H. Gajjar; Jai D. Jeyaraman; Mansi V. Patel; Rutu R. Joshi (Aerosol Science and Engineering, 2022)

Transcriptomic Signatures of Pearl Oyster Pinctada Maxima in Response to Acute Salinity Stress - Haijun Wei; Mingqiang Chen; Zhenghua Deng; Jing Sun; Jingru Yang; Wang Zhao; Youning Li; Zhenhua Ma; Yu Wang; Gang Yu (Frontiers in Marine Science, 2022)
Acute salinity stress can impact many physiological processes of marine shellfish. The responses of Pinctada maxima to salinity stress, especially the osmotic pressure regulation and immune response, are of great significance to health. To investigate the molecular changes in response to acute salinity stress, the pearl oysters were transferred from 30 ppt (C) to 40 ppt (HS) and 20 ppt (LS) for 12 h, and the transcriptome analysis was conducted on the gills. Compared to the control, there were 6613 (3253 up-regulated and 3360 down-regulated) differentially expressed genes (DEGs), 4395 (2180 up-regulated and 2215 down-regulated) DEGs observed in HS and LS, respectively. The related molecular biological processes and potential functions were explored from enrichment analysis. A total of 332 KEGG pathways (including 1514 genes) and 308 KEGG pathways (including 731 genes) were enriched in C vs. HS and C vs. LS, respectively. In addition, there are 1559 DEGs shared by C vs. HS group and C vs. LS group, and the results of the KEGG function annotation showed that 7 DEGs were involved in membrane transport, and 34 DEGs were involved in the immune system. The correlation network for expression of genes shows that the expression of 3 genes was significantly correlated with each other in membrane transport, and there were significant correlations between the expression of 27 genes in immune response. The results of this study will be of great value in understanding the molecular basis of salinity stress adaptation in the pearl oyster P. maxima .

A Shuttling Protein Kank1 Plays Important Role in the Sex Determination in Yellow Drum - Sha Sun; Jieping Liu; Sen Zhang; Qiwei He; Wei Han; Kun Ye; Fang Han; Wanbo Li; Zhiyong Wang (Frontiers in Marine Science, 2022)
Sex is one of the most important scientific topics, and the existence of sex dimorphism is a conserved feature in vertebrate taxa. The research on sex-determining genes and sex chromosome evolution is a hot topic in biology. The majority of sex-determining genes expressed in somatic cells, and reciprocal interactions between germ cells and somatic cells, are important for gonadal differentiation. However, the knowledge of how signals are transmitted between somatic cells and germ cells remains unclear. In this study, we confirmed the 36 dph was a sex determination critical stage in yellow drum through transcriptome analysis at the early development stages. We further found that Kank1 participated in the germ cells’ motility process in yellow drum through KEGG pathway analysis together with protein-protein interaction network. With the dual-luciferase reporter assay, we detected that Kank1 increased the transcription of dmrt1_Luc gene in CHO cells and 293T cells. Additionally, we observed that Kank1 was not only expressed in the cytoplasm but also in the nucleus in CHO cells through a fluorescence microscope. These results suggest that Kank1 acts as a shuttling protein as in humans and may play a difunctional role at the early gonad development stage in yellow drum, and it not only participated in the germ cells’ motility but also increased the expression of dmrt1 in yellow drum.

Study of the heterologous gene expression characteristics of a new clone of a cell line derived from Papilio xuthus and its serum-free adaptation - Wei-Feng Ding; Na Sun; Zhi-Gang Liu; Xin Zhang; Xian Li; Hang Chen; Ying Feng (In Vitro Cellular & Developmental Biology - Animal, 2022)

Urinary phthalate metabolites in pregnant women: occurrences, related factors, and association with maternal hormones - Wei Wu; Zhi-li Ma; Fang Yang; Ping Wu; De-xin Zhang; Rong Zeng; Dan-ling Sun; Liu Cao (Environmental Science and Pollution Research, 2022)

Geochemical characteristics and growth suitability assessment of Scutellaria baicalensis Georgi in the Earth’s critical zone of North China - Xia Li; Xiao-feng Wei; Jin Wu; Zhi-qiang Yin; Li-qin Wan; Hou-yun Sun; Yong-long An (Journal of Mountain Science, 2022)

Correction to: Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Two new phenylpropanoid glycosidic compounds from the pseudobulbs of Pleione bulbocodioides and their hepatoprotective activity - Shao-Wei Han; Si-Yuan Shao; Hua Sun; Shuai Li (Natural Product Research, 2022)

Chitin deacetylase: from molecular structure to practical applications - Ziyang Huang; Xueqin Lv; Guoyun Sun; Xinzhu Mao; Wei Lu; Yanfeng Liu; Jianghua Li; Guocheng Du; Long Liu (Systems Microbiology and Biomanufacturing, 2022)

Gene editing and its applications in biomedicine - Guanglei Li; Xiangyang Li; Songkuan Zhuang; Liren Wang; Yifan Zhu; Yangcan Chen; Wen Sun; Zeguang Wu; Zhuo Zhou; Jia Chen; Xingxu Huang; Jin Wang; et al. (Science China Life Sciences, 2022)

Soil phosphorus availability and stoichiometry determine microbial activity and functional diversity of fluvo-aquic soils under long-term fertilization regimes - Wei He; Wenhua Ye; Mingjie Sun; Yaping Li; Manman Chen; Meng Wei; Guoqing Hu; Quangang Yang; Hong Pan; Yanhong Lou; Hui Wang; Yuping Zhuge (Journal of Soils and Sediments, 2022)

Characterization, expression, and function analysis of AKR1A1 gene from yellow catfish (Tachysurus fulvidraco) - Long Yang; Shuting Zheng; Dan Kong; Shenghan Xiang; Jianfen Wu; Neng Wan; Wenxiu Sun; Wei Li (Fish Physiology and Biochemistry, 2022)

Correction to: Spindle‑related brain activation in patients with insomnia disorder: An EEG‑fMRI study - Yan Shao; Guangyuan Zou; Serik Tabarak; Jie Chen; Xuejiao Gao; Ping Yao; Jiayi Liu; Yuezhen Li; Nana Xiong; Wen Pan; Mengying Ma; Shuqin Zhou; et al. (Brain Imaging and Behavior, 2022)

Spindle-related brain activation in patients with insomnia disorder: An EEG-fMRI study - Yan Shao; Guangyuan Zou; Serik Tabarak; Jie Chen; Xuejiao Gao; Ping Yao; Jiayi Liu; Yuezhen Li; Nana Xiong; Wen Pan; Mengying Ma; Shuqin Zhou; et al. (Brain Imaging and Behavior, 2022)

Damaging effects of TiO2 nanoparticles on the ovarian cells of Bombyx mori - Yilong Fang; Mingli Dai; Wentao Ye; Fanchi Li; Haina Sun; Jing Wei; Bing Li (Biological Trace Element Research, 2022)

Alkaloids constituents from the roots of Phragmites australis (Cav.) Trin. ex Steud. with their cytotoxic activities - Ying Chen; Li Li; Li-Rui Jiang; Jia-Yin Tan; Li-Na Guo; Xiao-Li Wang; Wei Dong; Wen-Bao Wang; Ji-Kai Sun; Bo Song (Natural Product Research, 2022)

Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra) - Li-Chao Pan; Yang-Yang Sun; Xiao-Ling Zhang; Zhen-Yuan Zhu; Chun-Yu Liu; Hui-Qing Sun; Xue-Qing Geng; Wei Jiang; Jia-He Wang (Natural Product Research, 2022)

Application of ADSCs and their Exosomes in Scar Prevention - Cong Li; Shuqiang Wei; Quanchen Xu; Yu Sun; Xuchao Ning; Zhiguo Wang (Stem Cell Reviews and Reports, 2022)
Scar is a common way of healing after tissue injury. The poor scar healing will not only cause dysfunction of tissues and organs but also affect the appearance of the patients’ body surface, which causes the pressure of life and spirit to the patients. However, the formation of scar tissue is an extremely complex process and its mechanism is not fully understood. At present, there is no treatment method to eliminate scars completely. Fibroblasts are the most abundant cells in the dermis, which have the ability to synthesize and remodel extracellular matrix (ECM). Myofibroblasts actively participate in the wound healing process and influence the outcome. Therefore, both of them play important roles in wound healing and scar formation. Adipose tissue-derived stem cells (ADSCs) are pluripotent stem cells that can act on target cells by paracrine. Adipose tissue stem cell-derived exosomes (ADSC-Exos) are important secretory substances of ADSCs. They are nanomembrane vesicles that can transport a variety of cellular components and fuse with target cells. In this review, we will discuss the effects of ADSCs and ADSC-Exos on the behavior of fibroblasts and myofibroblasts during wound healing and scarring stage in combination with recent studies. Graphical Abstract

Development of MEMS directed evolution strategy for multiplied throughput and convergent evolution of cytochrome P450 enzymes - Li Ma; Fengwei Li; Xingwang Zhang; Hui Chen; Qian Huang; Jing Su; Xiaohui Liu; Tianjian Sun; Bo Fang; Kun Liu; Dandan Tang; Dalei Wu; et al. (Science China Life Sciences, 2022)

Inhibition of red chlorophyll catabolite reductase improved chlorophyll and carotenoid synthesis in tobacco - Chen Dong; Mei Zhang; Fang Wei; Yushuang Guo; Lili Qin; Pan Wei; Yubo Wang; Lifeng Jin; Weina Song; Tao Sun; Feng Li; Ran Wang (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

RhoGEF Trio Regulates Radial Migration of Projection Neurons via Its Distinct Domains - Chengwen Wei; Mengwen Sun; Xiaoxuan Sun; Hu Meng; Qiongwei Li; Kai Gao; Weihua Yue; Lifang Wang; Dai Zhang; Jun Li (Neuroscience Bulletin, 2022)
The radial migration of cortical pyramidal neurons (PNs) during corticogenesis is necessary for establishing a multilayered cerebral cortex. Neuronal migration defects are considered a critical etiology of neurodevelopmental disorders, including autism spectrum disorders (ASDs), schizophrenia, epilepsy, and intellectual disability (ID). TRIO is a high-risk candidate gene for ASDs and ID. However, its role in embryonic radial migration and the etiology of ASDs and ID are not fully understood. In this study, we found that the in vivo conditional knockout or in utero knockout of Trio in excitatory precursors in the neocortex caused aberrant polarity and halted the migration of late-born PNs. Further investigation of the underlying mechanism revealed that the interaction of the Trio N-terminal SH3 domain with Myosin X mediated the adherence of migrating neurons to radial glial fibers through regulating the membrane location of neuronal cadherin (N-cadherin). Also, independent or synergistic overexpression of RAC1 and RHOA showed different phenotypic recoveries of the abnormal neuronal migration by affecting the morphological transition and/or the glial fiber-dependent locomotion. Taken together, our findings clarify a novel mechanism of Trio in regulating N-cadherin cell surface expression via the interaction of Myosin X with its N-terminal SH3 domain. These results suggest the vital roles of the guanine nucleotide exchange factor 1 (GEF1) and GEF2 domains in regulating radial migration by activating their Rho GTPase effectors in both distinct and cooperative manners, which might be associated with the abnormal phenotypes in neurodevelopmental disorders.

Mitogenome of Knodus borki (Cypriniformes: Characidae): genomic characterization and phylogenetic analysis - Cheng-He Sun; Ya-Nan Zhang; Xiao-Shu Zeng; Da-Wei Liu; Qi Huang; Xiao-Li Zhang; Qun Zhang (Molecular Biology Reports, 2022)

Euler common spatial patterns for EEG classification - Jing Sun; Mengting Wei; Ning Luo; Zhanli Li; Haixian Wang (Medical & Biological Engineering & Computing, 2022)

Alternation of stromatolites and vertical burrows controlled by storm processes and sea-level changes in the middle Cambrian carbonates of central China - Bingchen Liu; Mingyue Dai; Yong’an Qi; Xiaofang Sun; Wei Zheng; Min Wang; Zhifeng Xing; Da Li; Yuchao Fan (Journal of Earth System Science, 2022)

Optimizing nitrogen fertilizer application under reduced irrigation strategies for winter wheat of the north China plain - Ying Liu; Meikun Han; Xiaonan Zhou; Wei Li; Chenghang Du; Yitao Zhang; Yinghua Zhang; Zhencai Sun; Zhimin Wang (Irrigation Science, 2022)

Inferring Gene Regulatory Networks Using the Improved Markov Blanket Discovery Algorithm - Wei Liu; Yi Jiang; Li Peng; Xingen Sun; Wenqing Gan; Qi Zhao; Huanrong Tang (Interdisciplinary Sciences: Computational Life Sciences, 2022)

Assessment of genetic diversity among Chinese high-oleic peanut genotypes using miniature inverted-repeat transposable element markers - Chuan Tang Wang; Guo Sheng Song; Zhi Wei Wang; Hong Ju Li; Hong Wei Han; Xiao Yuan Chi; Xiu Zhen Wang; Xiu Shan Sun (Genetic Resources and Crop Evolution, 2022)

3D Seismic Stability Analysis of Bench Slope with Pile Reinforcement - Sheng-yu Yang; Zhen Wang; Jia-man Wang; Ming-wei Gong; Jian-fei Li; Zhi-bin Sun (Geotechnical and Geological Engineering, 2022)

Effects of extreme precipitation on hospitalization risk and disease burden of schizophrenia in urban and rural Lu’an, China, from 2010 to 2019 - Yudong Wu; Zhenghai Yao; Gongyan Ma; Jian Cheng; Huabin Xu; Wei Qin; Weizhuo Yi; Rubing Pan; Qiannan Wei; Chao Tang; Xiangguo Liu; Yangyang He; et al. (Environmental Science and Pollution Research, 2022)

Diversity and spatiotemporal dynamics of fungal communities in the rhizosphere soil of Lycium barbarum L.: a new insight into the mechanism of geoherb formation - Yuekun Li; Kaili Chen; Siyang Liu; Xiaojie Liang; Yajun Wang; Xuan Zhou; Yue Yin; Youlong Cao; Wei An; Ken Qin; Yanfei Sun (Archives of Microbiology, 2022)
Lycium barbarum L. is a well-known traditional geoherb in Ningxia, China. The fruits of L. barbarum contain several dietary constituents, and thus, they exert many beneficial effects on human health. However, a few studies have been conducted on the geoherb L. barbarum and its rhizosphere soil fungal community. In this study, we determined the physicochemical properties and fungal community structure of rhizosphere soil of L. barbarum from three regions of China, namely Ningxia (NX), Qinghai (QH), and Xinjiang (XJ), during three development stages of L. barbarum . Soil pH varied between 7.56 and 8.60 across the three regions, indicating that alkaline soil is conducive to the growth of L. barbarum . The majority of soil properties in NX, an authentic geoherb-producing area, were substantially inferior to those in XJ and QH during all three developmental stages. Total sugar, polysaccharide (LBP), and flavonoid contents were the highest in wolfberry fruits from NX. High-throughput sequencing showed that the abundance of the soil fungal population in NX was higher than that in QH and XJ during the flowering and fruiting stage and summer dormant stage. Moreover, the soil fungal diversity increased with the development of wolfberry. Ascomycota and Mortierellomycota were the predominant phyla in the rhizosphere fungal communities in all samples. Redundancy analysis showed a significant correlation of the soil-available phosphorus and LBP of wolfberry fruits with the fungal community composition. The characteristics of rhizosphere fungal communities determined in the present study provide insights into the mechanism of geoherb formation in NX wolfberry.

Heavy metal pollution and risk assessment of farmland soil in eco-tourism resort - Qifa Sun; Zhuoan Sun; Jianheng Wang; Weiguo Xing; Guojie Hao; Zhijie Liu; Tao Liu; Zhonglin Sun; Xuguang Li; Hui Tian; Wei Zhu (Arabian Journal of Geosciences, 2022)

Safety design of tunnel lining structure considering bond-slip failure mechanism - Huibin Sun; Shuguang Song; Wei Lu; Quangang Ren; Xu Li; Xin Miao (Arabian Journal of Geosciences, 2022)

Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Synechococcus silicon accumulation in oligotrophic oceans - Yuqiu Wei; Jun Sun; Liuyang Li; Zhengguo Cui (Limnology and Oceanography, 2022)
Si accumulation by Synechococcus , small unicellular marine picocyanobacteria that dominate in nutrient‐depleted waters, is significant due to its potential to alter our understanding of the global Si cycle. To date, however, there are only a few studies on Si accumulation in individual Synechococcus cells. To determine the magnitude and variability of Synechococcus cellular Si content in oligotrophic oceans, we analyzed 1348 discrete cells collected from the understudied eastern Indian Ocean (EIO) and western Pacific Ocean (WPO). Synechococcus cellular Si quotas varied widely across both regions, ranging from 0 to 4651 amol Si cell −1 . While highly variable in range, average Si quotas were ~ 2.5‐fold lower in Synechococcus cells from the EIO (172 ± 304 amol Si cell −1 ) than in those from the WPO (438 ± 737 amol Si cell −1 ). The estimated contributions of Synechococcus to total and picoplankton biogenic Si stocks were Synechococcus has a small but persistent regional contribution to biogenic Si stocks. Here, we also made a first‐order estimate of the Synechococcus biogenic Si stock for the global ocean, that is, 0.06–0.09 Tmol Si, accounting for 2–3% of the global ocean diatom Si stock. No significant effects of temperature and dissolved inorganic N and P on cellular Si quotas were observed within these oligotrophic ecosystems. However, salinity, ambient dissolved Si, and N/P ratio were closely correlated with the variable Si quotas with different relationships. In addition, Synechococcu s cellular Si/P and Si/S ratios associated with physiological processes were significantly influenced by environmental and geographic variables. We thus suggest that the variance in cellular Si quotas may be indirectly driven by ambient variables via some unknown independent or strain‐dependent physiological processes.

Dysfunction of FadA‐cAMP signalling decreases Aspergillus flavus resistance to antimicrobial natural preservative Perillaldehyde and AFB1 biosynthesis - Kunlong Yang; Qingru Geng; Yue Luo; Rui Xie; Tongzheng Sun; Zhen Wang; Ling Qin; Wei Zhao; Man Liu; Yongxin Li; Jun Tian (Environmental Microbiology, 2022)
Summary Aspergillus flavus is an opportunistic fungal pathogen that colonizes agriculture crops with aflatoxin contamination. We found that Perillaldehyde (PAE) effectively inhibited A . flavus viability and aflatoxin production by inducing excess reactive oxygen species (ROS). Transcriptome analysis indicated that the Gα protein FadA was significantly induced by PAE. Functional characterization of FadA showed it is important for asexual development and aflatoxin biosynthesis by regulation of cAMP‐PKA signalling. The Δ fadA mutant was more sensitive to PAE, while Δ pdeL and Δ pdeH mutants can tolerate excess PAE compared to wild‐type A . flavus . Further RNA‐sequence analysis showed that fadA was important for expression of genes involved in oxidation–reduction and cellular metabolism. The flow cytometry and fluorescence microscopy demonstrated that Δ fadA accumulated more concentration of ROS in cells, and the transcriptome data indicated that genes involved in ROS scavenging were downregulated in Δ fadA mutant. We further found that FadA participated in regulating response to extracellular environmental stresses by increasing phosphorylation levels of MAPK Kinase Slt2 and Hog1. Overall, our results indicated that FadA signalling engages in mycotoxin production and A . flavus resistance to antimicrobial PAE, which provide valuable information for controlling this fungus and AF biosynthesis in pre‐ and postharvest of agricultural crops.

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Vinasse-based biochar magnetic composites: adsorptive removal of tetracycline in aqueous solutions - Yujia Xiang; Yuzhou Zhou; Bin Yao; Yuqing Sun; Eakalak Khan; Wei Li; Guihua Zeng; Jian Yang; Yaoyu Zhou (Environmental Science and Pollution Research, 2022)

The effects of protopine 6-hydroxylase (P6H) overexpression on benzylisoquinoline alkaloids in Macleaya cordata - Mengshan Sun; Xiubin Liu; Wei Liu; Zixuan Xu; Yuyu Wang; Li Zhou; Peng Huang; Jianguo Zeng (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Characterization of Grinding-Induced Subvisible Particles and Free Radicals in a Freeze-Dried Monoclonal Antibody Formulation - Zhen-Yi Jing; Guo-Li Huo; Min-Fei Sun; Bin-Bin Shen; Wei-Jie Fang (Pharmaceutical Research, 2022)

Damage and Failure of Hot Dry Rock under Cyclic Liquid Nitrogen Cold Shock Treatment: A Non-destructive Ultrasonic Test Method - Yong Sun; Cheng Zhai; Jizhao Xu; Xu Yu; Yuzhou Cong; Yangfeng Zheng; Wei Tang; Yujie Li (Natural Resources Research, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Responses and feedback of litter properties and soil mesofauna to herbaceous plants expansion into the alpine tundra on Changbai Mountain, China - Ying-jie Zhang; Ying-hua Jin; Jia-wei Xu; Hong-shi He; Yan Tao; Zhi-peng Yang; Jing Zhao; Yin-xia Diao; Chen-hui Sun; Mai-He Li (Journal of Mountain Science, 2022)

Effect of Temperature on the Acoustic Reflection Characteristics of Seafloor Surface Sediments - Dapeng Zou; Guican Ye; Wei Liu; Han Sun; Jun Li; Tibing Xiao (Journal of Ocean University of China, 2022)

Seven new glycosides from the leaves of Datura metel L. - Jin-Yan Tan; Yan Liu; Yan-Gang Cheng; Yan-Ping Sun; Xiao-Mao Li; Wei Guan; Juan Pan; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Biochanin A as an α-hemolysin inhibitor for combating methicillin-resistant Staphylococcus aureus infection - Jiaxuan Feng; Dazhong Sun; Li Wang; Xueting Li; Jiyu Guan; Lin Wei; Donghui Yue; Xingye Wang; Yicheng Zhao; Haimiao Yang; Wu Song; Bingmei Wang (World Journal of Microbiology and Biotechnology, 2022)

Identification of zones contaminated with phthalates and polycyclic aromatic hydrocarbons by concentrations in gridded soil with 1/6° latitude by 1/4° longitude resolution: a case study of Zhejiang, China - Mingzhe Lv; Wei Gao; Jiacheng Li; Xintao Ye; Tianwei Xu; Lu Liu; Shanshan Zhou; Jianqiang Sun; Anping Zhang (Journal of Soils and Sediments, 2022)

Inoculation with Rhizobacteria Enhanced Tolerance of Tomato (Solanum lycopersicum L.) Plants in Response to Cadmium Stress - Ting Wei; Yanni Sun; Noman Yashir; Xian Li; Junkang Guo; Xun Liu; HongLei Jia; Xinhao Ren; Li Hua (Journal of Plant Growth Regulation, 2022)

Characterization and Cys-directed mutagenesis of urate oxidase from Bacillus subtilis BS04 - Tong-tong Zhu; Hong-na Chen; Lei Yang; Ying-bao Liu; Wei Li; Wen-xiu Sun (Biologia, 2022)

Mural Cells in the Brain Capillaries: Pericytes - Ruihua Sun; Wei Li; Chenhao Gao; Jiewen Zhang; Junkui Shang (Current Tissue Microenvironment Reports, 2021)

Genetic diversity and population genetic structure of Neillia incisa in China: implications for genetic conservation - Cuiping Zhang; Gangyu Sun; Hai Wang; Xinqiang Jiang; Wei Li; Xiaoman Xie; Yizeng Lu; Kuiling Wang (Trees, 2021)

Overexpression of UDP-glycosyltransferase genes enhanced aluminum tolerance through disrupting cell wall polysaccharide components in soybean - Zhengbiao Wang; He Li; Zhanpeng Wei; Haoran Sun; Ying He; Jie Gao; Zhenming Yang; Jiangfeng You (Plant and Soil, 2021)

Molecular cloning and characterization of NPC1L1 in the Chinese tree shrew (Tupaia belangeri chinensis) - Xiuying Kui; Dandan Qiu; Wenguang Wang; Na Li; Pinfen Tong; Xiaomei Sun; Liangzi Jin; Wei Deng; Jiejie Dai; Caixia Lu (Molecular Biology Reports, 2021)

Specific protistan consumers and parasites are responsive to inorganic fertilization in rhizosphere and bulk soils - Fangfang Li; Anqi Sun; Xiaoyan Jiao; Li Bi; Yong Zheng; Ji-Zheng He; Hang-Wei Hu (Journal of Soils and Sediments, 2021)

Nanomedicine-based combination of dexamethasone palmitate and MCL-1 siRNA for synergistic therapeutic efficacy against rheumatoid arthritis - Yanmei Li; Shitong Wei; Yonghua Sun; Shihua Zong; Yameng Sui (Drug Delivery and Translational Research, 2021)

A novel thermophilic β-carotene 15,15′-monooxygenase with broad substrate specificity from the marine bacterium Candidatus Pelagibacter sp. HTCC7211 - Zhangde Long; Yuzhe Zhao; Yun Xue; Min Wang; Jigang Li; Zan Su; Jiansheng Sun; Qibin Liu; Hong Liu; Duobin Mao; Tao Wei (Biotechnology Letters, 2021)

Isolation and characterization of 38 SNP markers for the black rockfish, Sebastes schlegelii by next-generation sequencing - Xianggang Gao; Xiangbo Bao; Wei Sun; Yunfeng Li; Zongying Liu; Weidong Liu (Conservation Genetics Resources, 2021)

Luteirhabdus pelagi gen. nov., sp. nov., a novel member of the family Flavobacteriaceae, isolated from the West Pacific Ocean - Wen-Ting Ren; Fan-Xu Meng; Li-Li Guo; Li Sun; Xue-Wei Xu; Peng Zhou; Yue-Hong Wu (Archives of Microbiology, 2021)
A Gram-stain-negative, aerobic, and yellow-pigmented bacterium, designated A3-108 T , was isolated from seawater of the West Pacific Ocean. Cells were non-motile and rod-shaped, with carotenoid-type pigments. Strain A3-108 T grew at pH 6.0–8.5 (optimum 6.5) and 15–40 °C (optimum 28 °C), in the presence of 0.5–10% (w/v) NaCl (optimum 1.0%). It possessed the ability to produce H 2 S. Based on the 16S rRNA gene analysis, strain A3-108 T exhibited highest similarity with Aureisphaera salina A6D-50 T (90.6%). Phylogenetic analysis shown that strain A3-108 T affiliated with members of the family Flavobacteriaceae and represented an independent lineage. The principal fatty acids were iso-C 15:0 , iso-C 17:0 3-OH, iso-C 15:1 G, and summed feature 3 (C 16:1 ω 7 c and/or C 16:1 ω 6 c ). The sole isoprenoid quinone was MK-6. The major polar lipids were phosphatidylethanolamine, one unidentified aminophospholipid, one unidentified aminolipid and one unidentified lipid. The ANIb, in silico DDH and AAI values among the genomes of strain A3-108 T and three reference strains were 67.3–71.1%, 18.7–22.1%, and 58.8–71.4%, respectively. The G + C content was 41.0%. Distinctness of the phylogenetic position as well as differentiating chemotaxonomic and other phenotypic traits revealed that strain A3-108 T represented a novel genus and species of the family Flavobacteriaceae , for which the name Luteirhabdus pelagi gen. nov., sp. nov. is proposed (type strain, A3-108 T = CGMCC 1.18821 T = KCTC 82563 T ).

Characterization and identification of SFDC ‐1, a novel AmpC ‐type β‐lactamase in Serratia fonticola - Xu Dong; Peiyao Zhang; Kexin Zhou; Jialei Liang; Qiaoling Li; Xueya Zhang; Danying Zhou; Wei Lu; Zhewei Sun; Hongmao Liu; Junwan Lu; Xi Lin; et al. (Environmental Microbiology, 2021)
Summary The clinical and environmental infections caused by AmpC β‐lactamases have been increasingly reported recently. In this study, we characterize the novel chromosome‐encoded AmpC β‐lactamase SFDC‐1 identified in Serratia fonticola strain R28, which was isolated from a rabbit raised on a farm in southern China. SFDC‐1 shared the highest amino acid identity of 79.6% with the functionally characterized AmpC β‐lactamase gene bla YRC‐1 , although it had highly homologous functionally uncharacterized relatives in the same species from different sources, including some of the clinical significance. The cloned bla SFDC‐1 exhibited resistance to a broad spectrum of β‐lactam antibiotics, including most cephalosporins with the highest resistance to ampicillin, cefazolin and ceftazidime, with increased MIC levels ≥128‐fold compared with the control strains. The purified SFDC‐1 showed catalytic activities against β‐lactams with the highest catalytic activity to cefazolin. The genetic context of bla SFDC‐1 and its relatives was conserved in the chromosome, and no mobile genetic elements were found surrounding them.

Two new phenolic glycosides with anti-complementary activity from the roots of Sanguisorba officinalis L - Rongshen Wang; Jinfeng Sun; Mei Jin; Chao Ye; Jiaming Wang; Long Jin; Ying Jie Ma; Wei Zhou; Gao Li (Natural Product Research, 2021)

Triculata A, a novel compound from Tricyrtis maculata (D. Don) J. F. Macbr. with biological properties - Li Ren; Yun-Ze Wang; Wei Zhang; Rui Zhou; Ming Zhao; Zhi-Shu Tang; Jing Sun; Dong-Bo Zhang (Natural Product Research, 2021)

Cannabinoid receptor GPR55 activation blocks nicotine use disorder by regulation of AMPAR phosphorylation - Qingqing Liu; Jiaoyan Yu; Xi Li; Yanyan Guo; Ting Sun; Li Luo; Jing Ren; Wei Jiang; Ruitao Zhang; Peng Yang; Qi Yang (Psychopharmacology, 2021)

Synthesis of pyrazole-4-carboxamides as potential fungicide candidates - Cuntao Dong; Wei Gao; Xiaotian Li; Susu Sun; Jingqian Huo; Yanen Wang; Da Ren; Jinlin Zhang; Lai Chen (Molecular Diversity, 2021)

Nitrate sources and transformations along a mountain-to-plain gradient in the Taizi River basin in Northeast China - Yanli Li; Linxia Li; Wei Sun; Xijie Yin (Environmental Science and Pollution Research, 2021)

Research on evaluation of manufacturing cloud service oriented to environmental benefits of supply chain - Jinyu Wei; Yaoxi Liu; Li Wang; Xueshan Sun (Environmental Science and Pollution Research, 2021)

Nitrogen addition amplifies the nonlinear drought response of grassland productivity to extended growing‐season droughts - Bo Meng; Junqin Li; Gregory E. Maurer; Shangzhi Zhong; Yuan Yao; Xuechen Yang; Scott L. Collins; Wei Sun (Ecology, 2021)
Understanding the response of grassland production and carbon exchange to intra‐annual variation in precipitation and nitrogen addition is critical for sustainable grassland management and ecosystem restoration. We introduced growing‐season drought treatments of different lengths (15, 30, 45 and 60 d drought) by delaying growing‐season precipitation in a long‐term nitrogen addition experiment in a low diversity meadow steppe in northeast China. Response variables included aboveground biomass (AGB), ecosystem net carbon exchange (NEE), and leaf net carbon assimilation rate ( A ). In unfertilized plots drought decreased AGB by 13.7% after a 45‐d drought and 31.7% after a 60‐d drought (47.6% in fertilized plots). Progressive increases in the drought response of NEE were also observed. The effects of N addition on the drought response of productivity increased as drought duration increased, and these responses were a function of changes in AGB and biomass allocation, particularly root to shoot ratio. However, no significant effects of drought occurred in fertilized or unfertilized plots in the growing season a year after the experiment, N addition did limit the recovery of AGB from severe drought during the remainder of the current growing season. Our results imply that chronic N enrichment could exacerbate the effects of growing‐season drought on grassland productivity caused by altered precipitation seasonality under climate change, but that these effects do not carry over to the next growing season.

A new triterpenoid and other constituents with cytotoxic activity from the roots of Sanguisorba officinalis L - Rongshen Wang; Jinfeng Sun; Mei Jin; Lan Jin; Yanqiu Qi; Lihua Cao; Wei Zhou; Gao Li (Natural Product Research, 2021)

The severe toxicity of CuO nanoparticles to the photosynthesis of the prokaryotic algae Arthrospira sp - Xingkai Che; Ruirui Ding; Qiang Zhang; Yujie Li; Qi Sun; Yuting Li; Zishan Zhang; Wei Wang; Huiyuan Gao (Environmental Science and Pollution Research, 2021)

Effect of exogenous silicon and methyl jasmonate on the alleviation of cadmium-induced phytotoxicity in tomato plants - Ting Wei; Xian Li; Noman Yashir; Hong Li; Yanni Sun; Li Hua; Xinhao Ren; Junkang Guo (Environmental Science and Pollution Research, 2021)

The influence of light intensity and organic content on cultivation of Chlorella vulgaris in sludge extracts diluted with BG11 - Xiurong Chen; Yingying Yang; Quanling Lu; Xiaoli Sun; Shanshan Wang; Qiuyue Li; Xiao Wei; Yuan Wang (Aquaculture International, 2021)

Sesquiterpenoids from Artemisia argyi and their NO production inhibitory activity in RAW264.7 cells - Gui-Min Xue; Jin-Feng Xue; Chen-Guang Zhao; Zhen-Zhu Zhao; Yan-Jun Sun; Kun Du; Han-Wei Li; Wei-Sheng Feng (Natural Product Research, 2021)

Correlations between Dual-Pathway White Matter Alterations and Language Impairment in Patients with Aphasia: A Systematic Review and Meta-analysis - Jie Zhang; Shuchang Zhong; Liang Zhou; Yamei Yu; Xufei Tan; Min Wu; Peng Sun; Wei Zhang; Juebao Li; Ruidong Cheng; Yanfei Wu; Yanmei Yu; et al. (Neuropsychology Review, 2021)

Screening of stable internal reference genes by quantitative real-time PCR in humpback grouper Cromileptes altivelis - Xiaojuan Chen; Yun Sun; Panpan Zhang; Jianlong Li; Haiping Li; Caoying Wei; Zhenjie Cao; Yongcan Zhou (Journal of Oceanology and Limnology, 2021)

Urban trees in university campus: structure, function, and ecological values - Xueyan Wang; Yanlin Wang; Xiaohan Qu; Bing Huang; Zeming Li; Junjiao Sun; Xiaoqing Wei; Xiuying Yang (Environmental Science and Pollution Research, 2021)

The comprehensive landscape of miR-34a in cancer research - Sijing Li; Xiaohui Wei; Jinyong He; Quanquan Cao; Danyu Du; Xiaoman Zhan; Yuqi Zeng; Shengtao Yuan; Li Sun (Cancer and Metastasis Reviews, 2021)

Microbiogenic thrombolites from the Cambrian Miaolingian Series of southern North China Craton - Xiaofang Sun; Mingyue Dai; Yong’an Qi; Bingchen Liu; Wei Zheng; Zhifeng Xing; Min Wang; Da Li; Yuchao Fan (Carbonates and Evaporites, 2021)

A new benzophenone with biological activities from metabolites of butyrolactone I in rat faeces - Bing Liu; Ning Chen; Ying Xu; Jia-Wei Zhang; Yuan Sun; Li-Zhu Zhao; Yu-bin Ji (Natural Product Research, 2021)

TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage - Pengfei Xu; Ye Hong; Yi Xie; Kang Yuan; Juanji Li; Rui Sun; Xiaohao Zhang; Xiaolei Shi; Rongrong Li; Jiaonan Wu; Xinfeng Liu; Wei Hu; et al. (Translational Stroke Research, 2021)

A mutation in CsHY2 encoding a phytochromobilin (PΦB) synthase leads to an elongated hypocotyl 1(elh1) phenotype in cucumber (Cucumis sativus L.) - Liangliang Hu; Peng Liu; Zhuoshuai Jin; Jing Sun; Yiqun Weng; Peng Chen; Shengli Du; Aimin Wei; Yuhong Li (Theoretical and Applied Genetics, 2021)

CsKTN1 for a katanin p60 subunit is associated with the regulation of fruit elongation in cucumber (Cucumis sativus L.) - Hui Wang; Jing Sun; Fan Yang; Yiqun Weng; Peng Chen; Shengli Du; Aimin Wei; Yuhong Li (Theoretical and Applied Genetics, 2021)

Chronic Cyanuric Acid Exposure Depresses Hippocampal LTP but Does Not Disrupt Spatial Learning or Memory in the Morris Water Maze - Wei Sun; Yang Yang; Zexiang Wu; Xiao Chen; Wen Li; Lei An (Neurotoxicity Research, 2021)

Developing Fe/zeolite catalysts for efficient catalytic wet peroxidation of three isomeric cresols - Lili Chen; Wenjing Sun; Huangzhao Wei; Xuejing Yang; Chenglin Sun; Li Yu (Environmental Science and Pollution Research, 2021)

Separation and characterization of refractory colored dissolved effluent organic matter in a full-scale industrial park wastewater treatment plant - Ashraful Islam; Guangxi Sun; Wei Shang; Xingcan Zheng; Pengfeng Li; Min Yang; Yu Zhang (Environmental Science and Pollution Research, 2021)

Exposure to antibiotics and mental disorders in children: a community-based cross-sectional study - Jingjing Zhang; Kaiyong Liu; Liang Sun; Linsheng Yang; Xinji Liu; Yitian Zhu; Rong Wei; Zhongxiu Jin; Li Wang; Ying Ma; Sufang Wang; Annuo Liu; et al. (Environmental Geochemistry and Health, 2021)

Caulobacter endophyticus sp. nov., an endophytic bacterium harboring three lasso peptide biosynthetic gene clusters and producing indoleacetic acid isolated from maize root - Jun-lian Gao; Pengbo Sun; Yu-chen Sun; Jing Xue; Guoliang Wang; Li-wei Wang; Yunpeng Du; Xiuhai Zhang; Jian-guang Sun (Antonie van Leeuwenhoek, 2021)

Optical nanosensors for biofilm detection in the food industry: principles, applications and challenges - Hongbin Pu; Yiwen Xu; Da-Wen Sun; Qingyi Wei; Xiaoli Li (Critical Reviews in Food Science and Nutrition, 2021)

Two new flavonoid glucosides from the fruits of Sinopodophyllum hexandrum - Yan-Jun Sun; Hao-Jie Chen; Gui-Min Xue; Hui Chen; Yan-Li Zhang; Meng Li; Kun Du; Jun-Min Wang; Wei-Sheng Feng (Natural Product Research, 2021)

Restricted Feeding Resets Endogenous Circadian Rhythm in Female Mice Under Constant Darkness - Yue Mei; Huajing Teng; Zhigang Li; Cheng Zeng; Yuanyuan Li; Wei Song; Kaifan Zhang; Zhong Sheng Sun; Yan Wang (Neuroscience Bulletin, 2021)

Transforming growth factor β as a possible independent factor in chronic hepatitis B - Ming-hui Li; Yao Lu; Fang-fang Sun; Qi-qi Chen; Lu Zhang; Hui-hui Lu; Zhan Zeng; Wei Yi; Yao Xie (Archives of Virology, 2021)

Foetidibacter luteolus gen. nov., sp. nov., isolated from the rhizosphere of Salvia miltiorrhiza - Qian Pu; Guo-hong Zeng; Gui-wei Wang; Ling-er Lu; Ang Li; Xu-rui Cheng; Xue-ying Wang; Ou Li; Cong Sun; Xiu-fang Hu (Archives of Microbiology, 2021)

Proteome landscape and spatial map of mouse primordial germ cells - Pan Wang; Yilong Miao; Xiao-Han Li; Na Zhang; Qilong Wang; Wei Yue; Shao-Chen Sun; Bo Xiong; Jie Qiao; Mo Li (Science China Life Sciences, 2021)

Identification of differentially expressed genes associated with aluminum resistance in the soybean plant - Jing-xuan Wang; Bo Wang; Lu-bin Cui; Hao Xie; Run-zhi Li; Cheng Wang; Zhang-jie Nan; Yu-shu Liu; Jing-yu Ma; Yun-jin Sun; Wei-yu Li (Physiology and Molecular Biology of Plants, 2021)

Ziziphus jujuba Mill., a plant used as medicinal food: a review of its phytochemistry, pharmacology, quality control and future research - Shi-Jun Liu; Yan-Ping Lv; Zhi-Shu Tang; Yu Zhang; Hong-Bo Xu; Dong-Bo Zhang; Chun-Li Cui; Hong-Bo Liu; Huan-Huan Sun; Zhong-Xing Song; Si-Min Wei (Phytochemistry Reviews, 2021)

Geochemically Constrained Prospectivity Mapping Aided by Unsupervised Cluster Analysis - Shuai Zhang; Emmanuel John M. Carranza; Keyan Xiao; Zhenghui Chen; Nan Li; Hantao Wei; Jie Xiang; Li Sun; Yang Xu (Natural Resources Research, 2021)

Alterinioella nitratireducens gen. nov., sp. nov., Isolated from Seawater in the West Pacific Ocean - Yan-Hui Kong; Cong Sun; Li-Li Guo; Lin Xu; Yue-Hong Wu; Xue-Wei Xu (Current Microbiology, 2021)

PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2 - Wei Gu; Yutong Cheng; Su Wang; Tao Sun; Zhizhong Li (Cardiovascular Toxicology, 2021)
Epigenetic regulations essentially participate in the development of cardiomyocyte hypertrophy. PHD finger protein 19 (PHF19) is a polycomb protein that controls H3K36me3 and H3K27me3. However, the roles of PHF19 in cardiac hypertrophy remain unknown. Here in this work, we observed that PHF19 promoted cardiac hypertrophy via epigenetically targeting SIRT2. In angiotensin II (Ang II)-induced cardiomyocyte hypertrophy, adenovirus-mediated knockdown of Phf19 reduced the increase in cardiomyocyte size, repressed the expression of hypertrophic marker genes Anp and Bnp , as well as inhibited protein synthesis. By contrast, Phf19 overexpression promoted Ang II-induced cardiomyocyte hypertrophy in vitro. We also knocked down Phf19 expression in mouse hearts in vivo. The results demonstrated that Phf19 knockdown reduced Ang II-induced decline in cardiac fraction shortening and ejection fraction. Phf19 knockdown also inhibited Ang II-mediated increase in heart weight, reduced cardiomyocyte size, and repressed the expression of hypertrophic marker genes in mouse hearts. Further mechanism studies showed that PHF19 suppressed the expression of SIRT2, which contributed to the function of PHF19 during cardiomyocyte hypertrophy. PHF19 bound the promoter of SIRT2 and regulated the balance between H3K27me3 and H3K36me3 to repress the expression of SIRT2 in vitro and in vivo. In human hypertrophic hearts, the overexpression of PHF19 and downregulation of SIRT2 were observed. Of importance, PHF19 expression was positively correlated with hypertrophic marker genes ANP and BNP but negatively correlated with SIRT2 in human hypertrophic hearts. Therefore, our findings demonstrated that PHF19 promoted the development of cardiac hypertrophy via epigenetically regulating SIRT2.

First detection and complete genome analysis of the Lyon IARC polyomavirus in China from samples of diarrheic cats - Yuying Li; Haixin Huang; Tian Lan; Wei Wang; Jie Zhang; Min Zheng; Liang Cao; Wenchao Sun; Huijun Lu (Virus Genes, 2021)

Pyrolysis characteristics of organic-rich shale from the Chang 7 member of Triassic Yanhe Profile in Ordos Basin - Zhenlong Ge; Qiang Sun; Delu Li; Qingmin Shi; Shaoni Wei; Tian Yang (Arabian Journal of Geosciences, 2021)

Living coccolithophores in the western Pacific Ocean with mesoscale eddies - Danyue Huang; Haijiao Liu; Jun Sun; Yuqiu Wei; Liuyang Li; Guicheng Zhang; Laxman Pujari (Acta Oceanologica Sinica, 2021)

Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020 - Encheng Sun; Zhenjiang Zhang; Zilong Wang; Xijun He; Xianfeng Zhang; Lulu Wang; Wenqing Wang; Lianyu Huang; Fei Xi; Haoyue Huangfu; Ghebremedhin Tsegay; Hong Huo; et al. (Science China Life Sciences, 2021)

Diversity, metabolism and cultivation of archaea in mangrove ecosystems - Cui-Jing Zhang; Yu-Lian Chen; Yi-Hua Sun; Jie Pan; Ming-Wei Cai; Meng Li (Marine Life Science & Technology, 2021)

Quantitative food web structure and ecosystem functions in a warm-temperate seagrass bed - Xiaoxiao Li; Wei Yang; Tao Sun; Ursula Gaedke (Marine Biology, 2021)

An Improved DDV Algorithm for the Retrieval of Aerosol Optical Depth From NOAA/AVHRR Data - Ruibo Li; Lin Sun; Huiyong Yu; Jing Wei; Xinpeng Tian (Journal of the Indian Society of Remote Sensing, 2021)

Shear strength and microstructure of silty clay subjected to CaSO4 solution and stability effect on a gypsum dump - Tao Wei; Guoqing Chen; Xiang Sun; Yang Li; Changan Qin; Ming Yan (Bulletin of Engineering Geology and the Environment, 2021)

Effect of fermentation bed on bacterial growth in the fermentation mattress material and cecum of ducks - Jian- mei Wang; Xin- meng Gan; Fa-jun Pu; Wan- xia Wang; Min Ma; Ling-li Sun; Ji-wei Hu; Bo Hu; Rong-ping Zhang; Li-li Bai; Liang Li; He-he Liu (Archives of Microbiology, 2021)

A study of groundwater characteristics in the Songhua River basin of China - Qifa Sun; Zhuoan Sun; Lingang Jia; Hui Tian; Xiaodong Guo; Xuguang Li; Wei Zhu (Arabian Journal of Geosciences, 2021)

Cellulomonas taurus sp. nov., a novel bacteria with multiple hydrolase activity isolated from livestock, and potential application in wastewater treatment - Sha-Sha Zhang; Jian-Feng Xu; Xiao-LI Sun; Wei Guo; Zeng-Shan Liu (Antonie van Leeuwenhoek, 2021)

Comparison of transpiration of differently aged apple orchards on the Loess Plateau of China at multiple temporal scales - Rui Zhang; Di Wang; Haowei Sun; Chaohui Wei; Li Wang (Hydrological Sciences Journal, 2021)

Two novel flavonoids from the leaves of Rhododendron dauricum L. with their inhibition of TNF-α production in LPS-induced RAW 264.7 cells - Chao Ye; Mei Jin; Chunshi Jin; Rongshen Wang; Jiaming Wang; Ying Zhang; Sainan Li; Jinfeng Sun; Wei Zhou; Gao Li (Natural Product Research, 2021)

Geochronology, geochemistry, and Sr–Nd–Hf isotopes of the Late Permian–Early Triassic granitoids in Eastern Kunlun Orogen, Northwest China: petrogenesis and implications for geodynamic setting - Hao-Ri Xue; Feng-Yue Sun; Liang Li; Wei Xin (International Geology Review, 2021)

Effects of Spray Parameters on the Effective Spray Width of Single-Rotor Drone in Sugarcane Plant Protection - Ping Zhang; Wei Zhang; Hai-Tian Sun; Feng-Guang He; Hai-Ba Fu; Li-Qiang Qi; Li-Juan Yu; Li-Yu Jin; Bo Zhang; Jian-Sheng Liu (Sugar Tech, 2021)

Identification of dicyclohexyl phthalate as a glucocorticoid receptor antagonist by molecular docking and multiple in vitro methods - Yue Leng; Yonghai Sun; Wei Huang; Chengyu Lv; Jingyan Cui; Tiezhu Li; Yongjun Wang (Molecular Biology Reports, 2021)

The Roles of Epinephelus coioides miR-122 in SGIV Infection and Replication - Hong-Yan Sun; Yu-Ling Su; Pin-Hong Li; Jia-Yang He; He-Jia Chen; Gang Wang; Shao-Wen Wang; Xiao-Hong Huang; You-Hua Huang; Qi-Wei Qin (Marine Biotechnology, 2021)
In mammals, mature miR-122 is 22 nucleotides long and can be involved in regulating a variety of physiological and biological pathways. In this study, the expression profile and effects of grouper Epinephelus coioides miR-122 response to Singapore grouper iridovirus (SGIV) infection were investigated. The sequences of mature microRNAs (miRNAs) from different organisms are highly conserved, and miR-122 from E. coioides exhibits high similarity to that from mammals and other fish. The expression of miR-122 was up-regulated during SGIV infection. Up-regulation of miR-122 could significantly enhance the cytopathic effects (CPE) induced by SGIV, the transcription levels of viral genes (MCP, VP19, LITAF and ICP18), and viral replication; reduce the expression of inflammatory factors (TNF-a, IL-6, and IL-8), and the activity of AP-1 and NF-κB, and miR-122 can bind the target gene p38α MAPK to regulate the SGIV-induced cell apoptosis and the protease activity of caspase-3. The results indicated that SGIV infection can up-regulate the expression of E. coioides miR-122, and up-regulation of miR-122 can affect the activation of inflammatory factors, the activity of AP-1 and NF-κB, and cell apoptosis to regulate viral replication and proliferation.

Mass spectrometry-based proteomic analysis of potential infectious bursal disease virus VP3-interacting proteins in chicken embryo fibroblasts cells - Sun-Ting Ma; Yong-Shan Wang; Xiao-Li Wang; Xing-Xia Xia; Zhen-Wei Bi; Jing-Yu Wang; Yu-Mei Zhu; Wei Ouyang; Jing Qian (Virus Genes, 2021)

Global-Scale Diversity and Distribution Characteristics of Reef-Associated Symbiodiniaceae via the Cluster-Based Parsimony of Internal Transcribed Spacer 2 Sequences - Sanqiang Gong; Guangjun Chai; Wei Sun; Fengli Zhang; Kefu Yu; Zhiyong Li (Journal of Ocean University of China, 2021)

Nesterenkonia haasae sp. nov., an alkaliphilic actinobacterium isolated from a degraded pasture in Songnen Plain - Shuang Wang; Lei Sun; Dan Wei; Nimaichand Salam; Bao-Zhu Fang; Zhou-Yan Dong; Xiao-Yu Hao; Mingyi Zhang; Zhe Zhang; Wen-Jun Li (Archives of Microbiology, 2021)

Deep learning and comparative study of gas saturation models for tight sandstone reservoirs with strong heterogeneity: a case study of the Upper Triassic Xujiahe Formation in Sichuan Basin, China - Xiao Sun; Jia Liu; Yuanwei Sun; Xiaodong Dai; Chuanzhi Cui; Zhenzhen Wei; Xiao Li; Liqiang Wang (Arabian Journal of Geosciences, 2021)

Development of an In Vivo Predictive Dissolution Methodology of Topiroxostat Immediate-Release Tablet Using In Silico Simulation - Gang Li; Haiyang Yang; Wei Liu; Chen Shen; Yanhua Ji; Yilu Sun; Qing Huo; Yang Liu; Guopeng Wang (AAPS PharmSciTech, 2021)

Fertilization alters protistan consumers and parasites in crop‐associated microbiomes - Anqi Sun; Xiao‐Yan Jiao; Qinglin Chen; Pankaj Trivedi; Zixin Li; Fangfang Li; Yong Zheng; Yongxin Lin; Hang‐Wei Hu; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Crop plants carry an enormous diversity of microbiota that provide massive benefits to hosts. Protists, as the main microbial consumers and a pivotal driver of biogeochemical cycling processes, remain largely understudied in the plant microbiome. Here, we characterized the diversity and composition of protists in sorghum leaf phyllosphere, and rhizosphere and bulk soils, collected from an 8‐year field experiment with multiple fertilization regimes. Phyllosphere was an important habitat for protists, dominated by Rhizaria, Alveolata and Amoebozoa. Rhizosphere and bulk soils had a significantly higher diversity of protists than the phyllosphere, and the protistan community structure significantly differed among the three plant–soil compartments. Fertilization significantly altered specific functional groups of protistan consumers and parasites. Variation partitioning models revealed that soil properties, bacteria and fungi predicted a significant proportion of the variation in the protistan communities. Changes in protists may in turn significantly alter the compositions of bacterial and fungal communities from the top‐down control in food webs. Altogether, we provide novel evidence that fertilization significantly affects the functional groups of protistan consumers and parasites in crop‐associated microbiomes, which have implications for the potential changes in their ecological functions under intensive agricultural managements.

A new polyacetylene and other constituents with anti-inflammatory activity from Artemisia halodendron - Long Jin; Wei Zhou; Ren Li; Mei Jin; Chunshi Jin; Jinfeng Sun; Gao Li (Natural Product Research, 2021)

Spatial distribution and environmental significance of phytoliths in the surface soil of the Xilingol Grassland in Inner Mongolia, China - Chong-Xiao Sun; Hua Su; Cai-Qing Guo; Zhi-Wei Liu; Ya-Meng Li; Feng Qin; Hai-Ming Liu (Palaeobiodiversity and Palaeoenvironments, 2021)

Retraction Note to: Resibufogenin suppresses tumor growth and inhibits glycolysis in ovarian cancer by modulating PIM1 - Qian Li; Chuanwu Jiang; Yan Wang; Minghua Wei; Huijin Zheng; Yanqi Xu; Xuegang Xu; Fengyu Jia; Kai Liu; Gang Sun; Jianhua Zang; Ping Mo (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Analysis of slug interference tests conducted in an artificial fracture - Yunfeng Dai; Yanrong Zhao; Jin Lin; Jiangbo Han; Xiaomin Sun; Wei Li; Jiufu Liu (Hydrogeology Journal, 2021)

Comparison of Class 2 Integron Integrase Activities - Xiaotong Wang; Nana Kong; Mei Cao; Long Zhang; Muzhen Sun; Linlin Xiao; Gang Li; Quhao Wei (Current Microbiology, 2021)

Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications - Dingyu Wang; Li Sun; Guowei Zhang; Yang Liu; Zhaoguang Liang; Jing Zhao; Shuangli Yin; Mengqi Su; Song Zhang; Ying Wei; He Liu; Desen Liang; et al. (Cardiovascular Toxicology, 2021)

Developing GIS-based earthquake loss model: a case study of Baqiao District, China - Yixin Zhang; Shansuo Zheng; Longfei Sun; Li Long; Wei Yang; Lei Li (Bulletin of Earthquake Engineering, 2021)

Leaf spot of Sapindus mukorossi caused by Diaporthe biconispora in China - Yuan-Zhi Si; Jian-Wei Sun; De-Wei Li; Lin Huang; Yue Ju; Li-HuaZhu (Australasian Plant Pathology, 2021)

Pseudomonas laoshanensis sp. nov., isolated from peanut field soil - Ming-Qing Wang; Chu-Shu Zhang; Li-Na Yu; Wei-Qiang Yang; Kun Jiao; Kui-Jie Gong; Xiao-Yuan Chi; Jie Bi; Yu Song; Qing-Li Yang; Jian-Cheng Zhang; Gui-Wen Yang; et al. (Archives of Microbiology, 2021)

The deviation of thermal conductivity under different operating power is analyzed by linear heat source superposition method - Wei Zhu; XiaoSi Su; Xiao Li; QiFa Sun (Arabian Journal of Geosciences, 2021)

Least-squares reverse time migration method using the factorization of the Hessian matrix - Sun Xiao-Dong; Teng Hou-Hua; Ren Li-Juan; Wang Wei-Qi; Li Zhen-Chun (Applied Geophysics, 2021)

The MYB transcription factor Baymax1 plays a critical role in rice male fertility - Xiao-Jiao Xiang; Lian-Ping Sun; Ping Yu; Zheng-Fu Yang; Pei-Pei Zhang; Ying-Xin Zhang; Wei-Xun Wu; Dai-Bo Chen; Xiao-Deng Zhan; Riaz-Muhammad Khan; Adil Abbas; Shi-Hua Cheng; et al. (Theoretical and Applied Genetics, 2021)

In Situ Saturating Mutagenesis Screening Identifies a Functional Genomic Locus that Regulates Ucp1 Expression - Yan Qiu; Xiaojian Liu; Yingmin Sun; Shuang Li; Yuda Wei; Cheng Tian; Qiurong Ding (Phenomics, 2021)

Interleukin Enhancer Binding Factor 2 Regulates Cell Viability and Apoptosis of Human Brain Vascular Smooth Muscle Cells - Liang Wei; Cheng Yang; Guangxue Wang; Keqin Li; Yanfei Zhang; Hongxin Guan; Zhiyang Sun; Chunlong Zhong (Journal of Molecular Neuroscience, 2021)

Nonlinear decoupling of autotrophic and heterotrophic soil respiration in response to drought duration and N addition in a meadow steppe - Bo Meng; Raúl Ochoa-Hueso; Junqin Li; Shangzhi Zhong; Yuan Yao; Xuechen Yang; Scott L. Collins; Wei Sun (Biology and Fertility of Soils, 2021)

Correction to: Glaciimonas soli sp. nov., a soil bacterium isolated from the forest of a high elevation mountain - Wei-Sheng Huang; Li-Ting Wang; Jun-Ning Sun; Jwo-Sheng Chen; Ssu-Po Huang; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Two new quinones and six additional metabolites with potential anti-inflammatory activities from the roots of Juglans mandshurica - Shengjun Piao; Yanqiu Qi; Mei Jin; Shengbao Diao; Wei Zhou; Jinfeng Sun; Xinglin Jin; Gao Li (Natural Product Research, 2021)

Reactive oxygen species altering the metabolite profile of the marine-derived fungus Dichotomomyces cejpii F31-1 - Sharpkate Shaker; Ting-Ting Sun; Liang-Yue Wang; Wen-Zhe Ma; Dong-Lan Wu; Yong-Wei Guo; Jun Dong; Yan-Xiu Chen; Long-Ping Zhu; De-Po Yang; Hou-Jin Li; Wen-Jian Lan (Natural Product Research, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Effects of seismic force and pore water pressure on stability of 3D unsaturated hillslopes - Long Wang; Wenhua Liu; Wei Hu; Wugang Li; De’an Sun (Natural Hazards, 2021)

Porous Core/Dense Shell PLA Microspheres Embedded with High Drug Loading of Bupivacaine Crystals for Injectable Prolonged Release - Jinghua Xu; Yanjie Bai; Xuehui Li; Zhenping Wei; Lu Sun; Hongdan Yu; Hui Xu (AAPS PharmSciTech, 2021)

A unique porin meditates iron‐selective transport through cyanobacterial outer membranes - Guo‐Wei Qiu; Hai‐Bo Jiang; Hagar Lis; Zheng‐Ke Li; Bin Deng; Jin‐Long Shang; Chuan‐Yu Sun; Nir Keren; Bao‐Sheng Qiu (Environmental Microbiology, 2021)
Summary Cyanobacteria are globally important primary producers and nitrogen fixers with high iron demands. Low ambient dissolved iron concentrations in many aquatic environments mean that these organisms must maintain sufficient and selective transport of iron into the cell. However, the nature of iron transport pathways through the cyanobacterial outer membrane remains obscure. Here we present multiple lines of experimental evidence that collectively support the existence of a novel class of substrate‐selective iron porin, Slr1908, in the outer membrane of the cyanobacterium Synechocystis sp. PCC 6803. Elemental composition analysis and short‐term iron uptake assays with mutants in Slr1908 reveal that this protein is primarily involved in inorganic iron uptake and contributes less to the accumulation of other metals. Homologues of Slr1908 are widely distributed in both freshwater and marine cyanobacteria, most notably in unicellular marine diazotrophs. Complementary experiments with a homologue of Slr1908 in Synechococcus sp. PCC 7002 restored the phenotype of Synechocystis knockdown mutants, showing that this siderophore producing species also possesses a porin with a similar function in Fe transport. The involvement of a substrate‐selective porins in iron uptake may allow cyanobacteria to tightly control iron flux into the cell, particularly in environments where iron concentrations fluctuate.

A new diterpernoid glycoside from the fruit of Forsythia suspensa - Nan Ma; Chenzhi Sun; Qian Wei; Yajing Wang; Xinjia Yan; Chang Li; Yuehu Pei (Natural Product Research, 2020)

The partitioning behavior of trace elements in subduction zones: Advances and prospects - Xiaolin Xiong; Xingcheng Liu; Li Li; Jintuan Wang; Wei Chen; Mengfei Ruan; Ting Xu; Zhongxing Sun; Fangfang Huang; Jianping Li; Lei Zhang (Science China Earth Sciences, 2020)

The Arabidopsis KH-domain protein FLOWERING LOCUS Y delays flowering by upregulating FLOWERING LOCUS C family members - Guang-Yi Dai; Ding-Kang Chen; Yun-Peng Sun; Wei-Yi Liang; Yu Liu; Li-Qun Huang; Yong-Kang Li; Jia-Fan He; Nan Yao (Plant Cell Reports, 2020)

Identification of Amino Acid Dysregulation as a Potential Biomarker for Autism Spectrum Disorder in China - Mingyang Zou; Dexin Li; Luxi Wang; Ling Li; Shu Xie; Yu Liu; Wei Xia; Caihong Sun; Lijie Wu (Neurotoxicity Research, 2020)

Anxiolytic Effects of 8-O-Acetyl Shanzhiside Methylester on Acute and Chronic Anxiety via Inflammatory Response Inhibition and Excitatory/Inhibitory Transmission Imbalance - Ting Sun; Li Luo; Qin-Qin Tian; Wen-Ju Wang; Qing-Qing Liu; Le Yang; Kun Zhang; Wei Zhang; Ming-Gao Zhao; Qi Yang (Neurotoxicity Research, 2020)
Anxiety leads to a global decline in quality of life and increase in social burden. However, treatments are limited, because the molecular mechanisms underlying complex emotional disorders are poorly understood. We explored the anxiolytic effects of 8-O-acetyl shanzhiside methylester (8-OaS), an active component in Lamiophlomis rotata ( L . rotata ; Benth.) or Kudo, a traditional herb that has been shown to be effective in the clinical treatment of chronic pain syndromes in China. Two mouse anxiety models were used: forced swimming stress (FSS)–induced anxiety and complete Freund’s adjuvant (CFA)–induced chronic inflammatory pain. All animal behaviors were analyzed on the elevated plus maze and in the open-field test. 8-OaS significantly ameliorated anxiety-like behaviors in both anxiety models and inhibited the translation enhancement of GluN2A, GluN2B, and PSD95. Moreover, a reduction in GABA receptors disrupted the excitatory/inhibitory (E/I) balance in the basolateral amygdala (BLA), indicated by increased excitatory and decreased inhibitory presynaptic release. 8-OaS also blocked microglia activation and reduced the phosphorylation of p38, c-Jun N-terminal kinase (JNK), NF-κB p65, and tumor necrosis factor alpha (TNF-α) in the BLA of anxiety mice. 8-OaS exhibits obvious anxiolytic effects by regulating the excitatory/inhibitory (E/I) synaptic transmission and attenuating inflammatory responses in the BLA.

Image-Forming Visual Basis of Empathy for Pain in Mice - Kai-Wen Geng; Rui Du; Na Wei; Chun-Li Li; Yan Wang; Wei Sun; Tao Chen; Dong-Yu Wei; Yang Yu; Ting He; Wen-Jun Luo; Rui-Rui Wang; et al. (Neuroscience Bulletin, 2020)

Distribution Characteristics of Soil Organic Phosphorus Fractions in the Inner Mongolia Steppe - Xiaoya Zhu; Xiaorong Zhao; Qimei Lin; Alamus; Hai Wang; Honglin Liu; Wenxue Wei; Xuecheng Sun; Yongtao Li; Guitong Li (Journal of Soil Science and Plant Nutrition, 2020)

Immune characteristics distinguish patients with severe disease associated with SARS-CoV-2 - Xiaolei Li; Yang Liu; Junming Li; Longhua Sun; Jibin Yang; Fei Xu; Jing Zhou; Lagen Wan; Xinping Xu; Aiping Le; Wei Zhang (Immunologic Research, 2020)

Heme oxygenase 1 plays a crucial role in swamp eel response to oxidative stress induced by cadmium exposure or Aeromonas hydrophila infection - Yuwei Zang; Shuting Zheng; Fang Tang; Long Yang; Xiping Wei; Dan Kong; Wenxiu Sun; Wei Li (Fish Physiology and Biochemistry, 2020)

Toxicity Changes of Heavily Polluted River Sediments on Daphnia magna Before and After Dredging - Li-Ling Zhang; Zhou-Tao Pei; Ya-Ni Zhao; Jing Zhang; Rou-Rou Xu; Meng Zhang; Wen-Qiang Wang; Li-Wei Sun; Guang-Can Zhu (Bulletin of Environmental Contamination and Toxicology, 2020)

New sequence division method of shallow platform with natural gamma spectrometry data: implication for reservoir distribution—a case study from Majiagou Formation of Bozhong 21–22 structure, Bohai Bay Basin - Tao Ye; Ajuan Wei; Kunshun Gao; Zhe Sun; Fei Li (Carbonates and Evaporites, 2020)

Inverse gaussian beam stack imaging in 3D crosswell seismic exploration of deviated wells and Its application - Fei-Long Yang; Chong Zhao; Zheng-Rong Wei; Hui Sun; Hui-Feng Li; Chi Zhao; Hao Luo (Applied Geophysics, 2020)

An A 1 -type granite that borders A 2 -type: insights from the geochemical characteristics of the Zongyang A-type granite in the Lower Yangtze River Belt, China - Xiao-Yan Jiang; Kai Wu; Jin-Cheng Luo; Li-Peng Zhang; Wei Dong Sun; Xiao-Ping Xia (International Geology Review, 2020)

Solanrubiellin A, a hydroanthraquinone dimer with antibacterial and cytotoxic activity from Solanum lyratum - Hui Chen; Kun Du; Yan-Jun Sun; Zhi-You Hao; Yan-Li Zhang; Jiang Bai; Qing-Hua Wang; Hai-Yu Hu; Wei-Sheng Feng (Natural Product Research, 2020)

CD49a+CD49b+ NK cells induced by viral infection reflect an activated state of conventional NK cells - Wenhan Li; Jing Zhou; Xianwei Wang; Yuzhang Wu; Lilin Ye; Haiming Wei; Rui Sun; Zhigang Tian; Hui Peng (Science China Life Sciences, 2020)

Dorsolateral Striatal proBDNF Improves Reversal Learning by Enhancing Coordination of Neural Activity in Rats - Wei Sun; Hongxia Che; Jia Li; Dongxin Tang; Xiaoyun Liu; Wenhui Liu; Lei An (Molecular Neurobiology, 2020)

Structural Variability and Functional Prediction in the Epiphytic Bacteria Assemblies of Myriophyllum spicatum - Ling Xian; Tao Wan; Yu Cao; Junyao Sun; Ting Wu; Andrew Apudo Apudo; Wei Li; Fan Liu (Current Microbiology, 2020)

Complete genome sequence of a novel recombinant avian leukosis virus isolated from a three-yellow chicken - Tao Sun; Ximei Wang; Wei Han; Xiaoling Ma; Weili Yin; Baohai Fang; Xiao Lin; Yang Li (Archives of Virology, 2020)

Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis - Ning Xiao; Tian-long Liu; Hao Li; Hao-chen Xu; Jing Ge; Hong-yan Wen; Cong-xia Bai; Li Song; Ying-ying Sun; Yin-hui Zhang; Ru-tai Hui; Wei-hua Song; et al. (Translational Stroke Research, 2020)

LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer’s disease - Chia-Hao Fan; Chia-Wei Lin; Hei-Jen Huang; Guey-Jen Lee-Chen; Ying-Chieh Sun; Wenwei Lin; Chiung-Mei Chen; Kuo-Hsuan Chang; Ming-Tsan Su; Hsiu Mei Hsieh-Li (Psychopharmacology, 2020)

Mu-Opioid Receptors Expressed in Glutamatergic Neurons are Essential for Morphine Withdrawal - Xin-Yan Zhang; Qing Li; Ye Dong; Wei Yan; Kun Song; Yong-Qin Lin; Yan-Gang Sun (Neuroscience Bulletin, 2020)

A novel freshwater cyanophage vB_MelS-Me-ZS1 infecting bloom-forming cyanobacterium Microcystis elabens - Wei Lin; Dengfeng Li; Zhitong Sun; Yigang Tong; Xiaojun Yan; Chunlin Wang; Xianglilan Zhang; Guangqian Pei (Molecular Biology Reports, 2020)

Overexpression of PREX1 in oral squamous cell carcinoma indicates poor prognosis - Shu-Cheng Wan; Hao Wu; Hao Li; Wei-Wei Deng; Yao Xiao; Cong-Cong Wu; Lei-Lei Yang; Wen-Feng Zhang; Zhi-Jun Sun (Journal of Molecular Histology, 2020)

Bioaccumulation and toxic effects of penconazole in earthworms (Eisenia fetida) following soil exposure - Ruisheng Li; Zhiyuan Meng; Wei Sun; Ruoyue Wu; Ming Jia; Sen Yan; Sinuo Tian; Wentao Zhu; Zhiqiang Zhou (Environmental Science and Pollution Research, 2020)

Involvement of ROS/NLRP3 Inflammasome Signaling Pathway in Doxorubicin-Induced Cardiotoxicity - Shanshan Wei; Wanjun Ma; Xiaohui Li; Chuanhao Jiang; Taoli Sun; Yuanjian Li; Bikui Zhang; Wenqun Li (Cardiovascular Toxicology, 2020)

Plasticity of the resting-state brain: static and dynamic functional connectivity change induced by divergent thinking training - Jiangzhou Sun; Qinglin Zhang; Yu Li; Jie Meng; Qunlin Chen; Wenjing Yang; Dongtao Wei; Jiang Qiu (Brain Imaging and Behavior, 2020)

Transcriptome analysis of rice leaves in response to Rhizoctonia solani infection and reveals a novel regulatory mechanism - De Peng Yuan; Xiao Feng Xu; Woo-Jong Hong; Si Ting Wang; Xin Tong Jia; Yang Liu; Shuang Li; Zhi Min Li; Qian Sun; Qiong Mei; Shuai Li; Ki-Hong Jung; et al. (Plant Biotechnology Reports, 2020)

Structural characteristics and anti-complement activities of polysaccharides from Sargassum hemiphyllum - Weihua Jin; Qiufu Fang; Di Jiang; Tongtong Li; Bin Wei; Jiadong Sun; Wenjing Zhang; Zhongshan Zhang; Fuming Zhang; Robert J. Linhardt; Hong Wang; Weihong Zhong (Glycoconjugate Journal, 2020)

FGOALS-g3 Model Datasets for CMIP6 Flux-Anomaly-Forced Model Intercomparison Project - Yaqi Wang; Zipeng Yu; Pengfei Lin; Hailong Liu; Jiangbo Jin; Lijuan Li; Yanli Tang; Li Dong; Kangjun Chen; Yiwen Li; Qian Yang; Mengrong Ding; et al. (Advances in Atmospheric Sciences, 2020)
The Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) is an endorsed Model Intercomparison Project in phase 6 of the Coupled Model Intercomparison Project (CMIP6). The goal of FAFMIP is to investigate the spread in the atmosphere-ocean general circulation model projections of ocean climate change forced by increased CO 2 , including the uncertainties in the simulations of ocean heat uptake, global mean sea level rise due to ocean thermal expansion and dynamic sea level change due to ocean circulation and density changes. The FAFMIP experiments have already been conducted with the Flexible Global Ocean-Atmosphere-Land System Model, gridpoint version 3.0 (FGOALS-g3). The model datasets have been submitted to the Earth System Grid Federation (ESGF) node. Here, the details of the experiments, the output variables and some baseline results are presented. Compared with the preliminary results of other models, the evolutions of global mean variables can be reproduced well by FGOALS-g3. The simulations of spatial patterns are also consistent with those of other models in most regions except the North Atlantic and the Southern Ocean, indicating large uncertainties in the regional sea level projections of these two regions.

Does CMIP6 Inspire More Confidence in Simulating Climate Extremes over China? - Huanhuan Zhu; Zhihong Jiang; Juan Li; Wei Li; Cenxiao Sun; Laurent Li (Advances in Atmospheric Sciences, 2020)

Gnaq Protects PC12 Cells from Oxidative Damage by Activation of Nrf2 and Inhibition of NF-kB - Xin Sun; Guo-Ping Li; Pu Huang; Lu-Gang Wei; Jia-Zhi Guo; Li-Juan Ao; Di Lu; Shao-Chun Chen (NeuroMolecular Medicine, 2020)

A novel function of IRF9 in acute pancreatitis by modulating cell apoptosis, proliferation, migration, and suppressing SIRT1-p53 - Bin-Hua Xue; Yi Liu; Hu Chen; Yun Sun; Wei-Li Yu (Molecular and Cellular Biochemistry, 2020)

Metabolites from symbiotic bacteria of entomopathogenic nematodes have antimicrobial effects against Pythium myriotylum - Shaojie Shan; Haikun Ma; Yang Li; Cuiqing Huang; Xinghui Gu; Zhensheng Jiang; Bingjiao Sun; Chaoying Chen; Xianqin Wei; Guangshuang Shen; David Shapiro-Ilan; Weibin Ruan (European Journal of Plant Pathology, 2020)

Effects of Sulfamethoxazole Exposure on the Growth, Antioxidant System of Chlorella vulgaris and Microcystis aeruginosa - Xiaotong Dong; Shaohua Sun; Ruibao Jia; Lirong Xu; Wei Hou; Nannan Lu; Mingquan Wang; Qinghua Zhao; Li’an Hou (Bulletin of Environmental Contamination and Toxicology, 2020)

Evolution of Neolithic site distribution (9.0–4.0 ka BP) in Anhui, East China - Li Wu; Xiaoling Sun; Wei Sun; Cheng Zhu; Tongxin Zhu; Shuguang Lu; Hui Zhou; Qingchun Guo; Houchun Guan; Wei Xie; Rui Ke; Guiping Lin (Journal of Geographical Sciences, 2020)

Genesis of the Linghu Au deposit in Xiaoqinling Region, Henan province, China: Constraints from fluid inclusions and isotope systematics - Wei Zeng; Zhi-gao Wang; Duo Wan; Feng-yue Sun; Cheng-dong Li; Reng-an Yu; Jia-ying Wang; Jian-chang Xu (Arabian Journal of Geosciences, 2020)

A fundamental theorem for eco-environmental surface modelling and its applications - Tianxiang Yue; Na Zhao; Yu Liu; Yifu Wang; Bin Zhang; Zhengping Du; Zemeng Fan; Wenjiao Shi; Chuanfa Chen; Mingwei Zhao; Dunjiang Song; Shihai Wang; et al. (Science China Earth Sciences, 2020)

Sirt1-ROS-TRAF6 Signaling-Induced Pyroptosis Contributes to Early Injury in Ischemic Mice - Weijie Yan; Wei Sun; Jiahui Fan; Haiqing Wang; Song Han; Junfa Li; Yanling Yin (Neuroscience Bulletin, 2020)

Cloning and expression of Allophycocyanin gene from Gracilariopsis lemaneiformis and studying the binding sites of phycocyanobilin on its α and β subunits - Yalin Guo; Xiaonan Zang; Xuexue Cao; Feng Zhang; Deguang Sun; Menghui Shang; Rui Li; Zhaxi Yangzong; Xuehong Wei; Xuecheng Zhang (Journal of Applied Phycology, 2020)

Preoperative meloxicam versus postoperative meloxicam for pain control, patients’ satisfaction and function recovery in hip osteoarthritis patients who receive total hip arthroplasty: a randomized, controlled study - Lingyun Ren; Li Meng; Hong Yan; Wei Sun; Dan Yao (Inflammopharmacology, 2020)
This study aimed to compare the analgesic effect, patients’ satisfaction, tolerance and hip-joint function recovery by preoperative meloxicam versus postoperative meloxicam in treating hip osteoarthritis (OA) patients receiving total hip arthroplasty (THA). 132 hip OA patients who underwent THA surgery were allocated into postoperative analgesia (POST) and preoperative analgesia (PRE) groups at a 1:1 ratio. In the PRE group, patients took meloxicam 15 mg at 24 h pre-operation, 7.5 mg at 4 h, 24 h, 48 h and 72 h post-operation; in the POST group, patients received meloxicam 15 mg at 4 h post-operation, then 7.5 mg at 24 h, 48 h and 72 h post-operation. Furthermore, postoperative pain, consumption of patient-controlled analgesia (PCA), overall satisfaction and adverse events were evaluated within 96 h post-operation; meanwhile, Harris hip score was assessed within 6 months post-operation. Pain VAS at rest at 6 h, 12 h, 24 h, and pain VAS at passive movement at 6 h, 12 h were decreased in PRE group compared to POST group. In addition, additional consumption of PCA and the total consumption of PCA were both reduced in PRE group compared to POST group. Additionally, overall satisfaction in PRE group was higher at 24 h, 48 h and 72 h compared to POST group. While Harris hip score was of no difference between POST group and PRE group at M3 or M6. Besides, no difference in adverse events incidence was found between the two groups. In conclusion, preoperative meloxicam achieves better efficacy and similar tolerance compared to postoperative meloxicam in hip OA patients post THA.

Model test of the combined subgrade treatment by hydraulic sand fills and soil-cement mixing piles - Yang Sun; Jiu Cheng; Yiwei Li; Qi Chen; Wei Zhang; Guojian Shao (Bulletin of Engineering Geology and the Environment, 2020)

A longitudinal study of brain volume changes in rhesus macaque model infected with SIV - Bonan Song; Yunfang Li; Jiaojiao Liu; Haifeng Mi; Dan Liu; Wei Wang; Jun Sun; Yuanyuan Wang; Hongjun Li (Journal of NeuroVirology, 2020)

Mesorhizobium rhizophilum sp. nov., a 1-aminocyclopropane-1-carboxylate deaminase producing bacterium isolated from rhizosphere of maize in Northeast China - Jun-lian Gao; Jing Xue; Yu-chen Sun; Han Xue; En Tao Wang; Hui Yan; Shuai Tong; Li-wei Wang; Xiuhai Zhang; Jian-guang Sun (Antonie van Leeuwenhoek, 2020)

Glaciimonas soli sp. nov., a soil bacterium isolated from the forest of a high elevation mountain - Wei-Sheng Huang; Li-Ting Wang; Jun-Ning Sun; Jwo-Sheng Chen; Ssu-Po Huang; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2020)

Benzophenone glycosides from the pericarps of Aquilaria yunnanensis S. C. Huang - Hui Sun; Yun-Feng Zhang; Hui-Xia Huo; Peng-Wei Guan; Chao-Chao Wang; Hui-Na Yao; Yun-Fang Zhao; Peng-Fei Tu; Jun Li (Natural Product Research, 2020)

Aerosol-induced changes in sky polarization pattern: potential hint on applications in polarimetric remote sensing - Wei Chen; Shuang Bai; Dexuan Wang; Haimeng Zhao; Hao Sun; Lina Yi; Hengqian Zhao; Donghui Xie; Jouni Peltoniemi; Zhanqing Li (International Journal of Remote Sensing, 2020)