PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Protective Effect of Nanoselenium on Renal Oxidative Damage Induced by Mercury in Laying Hens - Yan Ma; Binyao Cheng; Yumeng Li; Zhuosi Wang; Xiang Li; Ao Ren; Qiujue Wu; Doudou Zhu; Bingbing Ren (Biological Trace Element Research, 2022)

A new model for plugging hydraulic fractures of tight sandstone reservoirs - Yin Zhang; Rangang Yu; Wendong Yang; Hao Xiang; Chuanlong Li; Guoliang Ma; Anqi Zhao; Yao Wang (Arabian Journal of Geosciences, 2022)

The Synergism between Methanogens and Methanotrophs and the Nature of their Contributions to the Seasonal Variation of Methane Fluxes in a Wetland: The Case of Dajiuhu Subalpine Peatland - Luwen Wang; Jiwen Ge; Liang Feng; Yaoyao Liu; Yu Li; Jiumei Wang; Xiang Xiao; Zhiqi Zhang (Advances in Atmospheric Sciences, 2022)

MdMYB88/124 modulates apple tree microRNA biogenesis through post-transcription processing and/or transcription pathway - Chun-dong Niu; Huan-ran Shi; Zi-tong Zhang; Tian-le Fan; Huan Dang; Peng-xiang Chen; Yin-peng Xie; Cha-na Bao; Feng-wang Ma; Qing-mei Guan; Xue-wei Li (Acta Physiologiae Plantarum, 2022)

Vertical patterns of chlorophyll a in the euphotic layer are related to mesoscale eddies in the South China Sea - Mei-Lin Wu; You-Shao Wang; Yu-Tu Wang; Fu-Lin Sun; Xiaomei Li; Fang-Fang Gu; Jing-Chang Xiang (Frontiers in Marine Science, 2022)
Phytoplankton closely connects with the hydrodynamics and biogeochemical environment of the ocean. While research focusing on both the physiochemical factors and hydrodynamics regulating phytoplankton has already been conducted, the coupling mechanism between mesoscale eddies and the vertical distribution of phyto plankton in the South China Sea (SCS) is still not well understood. Here, phytoplankton was studied under one weak-cold and two warm eddies along the 18°N transect in the SCS. The results show that the vertical distribution of chlorophyll (chl- a ) presented a similar pattern at all four sampling stations. The mixed layer is less than 50 m. It is the same as the meridional salinity gradients that may be distinguished above a depth of 60 m. The subsurface chlorophyll maximum at the edge of a warm (WI) and cold eddy (CI) at E413 and E411 was shallower than that at the edge of a warm eddy (WII) at E407 and E409, indicating that temperature and salinity may be the important driving factors. On the whole, mesoscale eddies had a significant influence on the vertical pattern of chl- a in the SCS during the study period.

Retrieval of Remotely Sensed Sediment Grain Size Evolution Characteristics along the Southwest Coast of Laizhou Bay Based on Support Vector Machine Learning - Xiang Yu; Chao Zhan; Yan Liu; Jialin Bi; Guoqing Li; Buli Cui; Longsheng Wang; Xianbin Liu; Qing Wang (Journal of Marine Science and Engineering, 2022)
Grain size is the basic property of intertidal zone sediment. Grain size acts as an indicator of sedimentary processes and geomorphological evolution under human and nature interactions. The remote sensing technique provides an alternative for sediment grain-size parameter monitoring with the advantages of wide coverage and real-time surveying. This paper attempted to map the distributions of three sediment grain size contents and the mean grain size with multitemporal Landsat images along the southwestern coast of Laizhou Bay, China, from 1989 to 2015. Considering the low correlations between the measured reflectance and grain-size parameters, we used a support vector machine (SVM) to develop a nonlinear calibration model by taking several band indices as input variables. Then, the performance of the back propagation neural network (BPNN) was determined and discussed with that of the SVM. The SVM performed better than the BPNN in calibrating the four grain-size parameters based on a comparison of R2 and the root-mean-square error (RMSE). Moreover, an atmospheric correction algorithm originally proposed for case II water enabled the TM\ETM+ images to be precisely atmospherically corrected in this study. The SVM-mapped spatial-temporal grain-size variation showed a coarsening trend, which agreed with that obtained during in situ measurements in a former study. The changes in Yellow River discharge and precipitation associated with the coarsening trend were further analyzed. The yielded results showed that the coarsening trend and reduction in tidal flat area might be aggravated with overutilization. More reasonable planning would be necessary in this case.

Epistatic interaction effect between chromosome 1BL (Yr29) and a novel locus on 2AL facilitating resistance to stripe rust in Chinese wheat Changwu 357-9 - Shuo Huang; Yibo Zhang; Hui Ren; Xiang Li; Xin Zhang; Zeyuan Zhang; Chuanliang Zhang; Shengjie Liu; Xiaoting Wang; Qingdong Zeng; Qilin Wang; Ravi P. Singh; et al. (Theoretical and Applied Genetics, 2022)

The FOXO family of transcription factors: key molecular players in gastric cancer - Ying Liu; Xiang Ao; Yi Jia; Xiaoge Li; Yu Wang; Jianxun Wang (Journal of Molecular Medicine, 2022)

Analysis on the spatial differentiation characteristics of poverty risk caused by disaster under the stress of geological disasters: a case study of Sichuan Province - Mingshun Xiang; Linsen Duan; Fengran Wei; Jin Yang; Wenheng Li; Chunjian Wang; Wenbo Yang; Qiuchi Deng (Environmental Science and Pollution Research, 2022)

Expression profiling of the mitogen-activated protein kinase gene family reveals their diverse response pattern in two different salt-tolerant Glycyrrhiza species - Aiping Cao; Ling Gao; Fei Wang; Xuechen Tong; Shuangquan Xie; Xifeng Chen; Tianxin Lu; Haitao Shen; Hailiang Liu; Xiang Jin; Hongbin Li (Genes & Genomics, 2022)

Historical biogeography of the gingers and its implications for shifts in tropical rain forest habitats - Jian‐Li Zhao; Xiang‐Qin Yu; W. John Kress; Ya‐Li Wang; Yong‐Mei Xia; Qing‐Jun Li (Journal of Biogeography, 2022)
Aim The relationships between biome shifts and global environmental changes in temperate zone habitats have been extensively explored; yet, the historical dynamics of taxa found in the tropical rain forest (TRF) remain poorly known. This study aims to reconstruct the relationships between tropical rain forest shifts and global environmental changes through the patterns of historical biogeography of a pantropical family of monocots, the Zingiberaceae. Location Global. Taxon Zingiberaceae. Methods We sampled DNA sequences (nrITS, trn K, trn L‐ trn F and psb A‐ trn H) from GenBank for 77% of the genera, including 30% of species, in the Zingiberaceae. Global fossil records of the Zingiberaceae were collected from literatures. Rates of speciation, extinction and diversification were estimated based on phylogenetic data and fossil records through methods implemented in BAMM. Ancestral ranges were estimated using single‐tree BioGeoBEARS and multiple‐trees BioGeoBEARS in RASP. Dispersal rate through time and dispersal rate among regions were calculated in R based on the result of ancestral estimation. Results The common ancestor of the Zingiberaceae likely originated in northern Africa during the mid‐Cretaceous, with later dispersal to the Asian tropics. Indo‐Burma, rather than Malesia, was likely a provenance of the common ancestor of Alpinioideae–Zingiberoideae. Several abrupt shifts of evolutionary rates from the Palaeocene were synchronized with sudden global environmental changes. Main conclusions Integrating phylogenetic patterns with fossil records suggests that the Zingiberaceae dispersed to Asia through drift of the Indian Plate from Africa in the late Palaeocene. Formation of island chains, land corridors and warming temperatures facilitated the emigration of the Zingiberaceae to a broad distribution across the tropics. Moreover, dramatic fluctuations of the speciation rate of Zingiberoideae appear to have been synchronized with global climate fluctuations. In general, the evolutionary history of the Zingiberaceae broadens our understanding of the association between TRF shifts in distribution and past global environmental changes, especially the origin of TRF in Southeast Asia.

Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells - Zhangyu Yao; Xiang Li; Jun Gao; Yutao Wang; Linmei Xiao; Xinxia Chang; Fangzhou Liu; Zhenqing Feng; Xiao Zhang (Human Cell, 2022)

Fine mapping qKRN5.04 provides a functional gene negatively regulating maize kernel row number - Yixin An; Lin Chen; Yong-Xiang Li; Chunhui Li; Yunsu Shi; Dengfeng Zhang; Yu Li; Tianyu Wang (Theoretical and Applied Genetics, 2022)

Sandstorms cause shrinkage of Haloxylon ammodendron shrubs and limit their self-renewal - Sheng-bo Shi; Dang-wei Zhou; Fang-lin Wang; Rui Shi; Tao Sun; Tian-cai Li; Jia-lin Ma; Xiang Wan; Jian-ping Ma; Jing-nian Tang (Theoretical and Experimental Plant Physiology, 2022)
Haloxylon ammodendron is an excellent windproof and sand-fixing species whose shrubs are widely cultivated in arid desert areas of northwest China but are now at risk of degradation and shrinkage. Using the chlorophyll fluorescence image analysis technique, the response of photosystem II (PSII) photochemical efficiency and non-photochemical quenching capacity to sediment-carrying wind and sand-free wind (both 12 m s −1 ) lasting for 10, 20, and 40 min were studied with seedlings in a wind tunnel. The results indicated that the sand-free wind had little influence on the maximum quantum efficiency of PSII photochemistry, F v / F m , which was approximately 0.80 on average; however, the F v / F m decreased over exposure time in the sediment-carrying wind group, with values smaller than those in the wind-only group. The non-photochemical quenching was sensitive to wind erosion, and sediment-carrying wind could aggravate the reduction in non-photochemical quenching ( NPQ ). Except for the 10 min duration, the maximum quantum efficiency of PSII photochemistry after dark recovery for 15 min, F v r / F m r , was lower in seedlings exposed to sediment-carrying wind than in those in the wind-only group. Compared to wind-only, wind-blown sand led to a water imbalance and withering in seedlings, causing the concentration of photosynthetic pigments (when based on the fresh mass of green branches) to not decrease. With a longer exposure time to sediment-carrying wind, both the probability and extent of lignified spots occurring increased in green assimilative branches. Our results demonstrated that sediment-carrying wind at 12 m s −1 lasting for 20 min or more could cause irreversible damage to the photosynthetic apparatus of H. ammodendron seedlings. Therefore, frequent and strong sandstorms are the main disturbance factors leading to shrinkage of shrubs and limiting their self-renewal.

Prediction of drought/flood intensities based on a 500-year time series in three different climate provinces of China - Yu Peng; Zhaohua Wang; Yixin Cui; Yali Su; Yiyun Tang; Shiqian Luo; Lianlin Liu; Yanqiu Zhou; Jihui Dong; Wentao Wang; Xiang Li; Jiaxin Shang; et al. (Regional Environmental Change, 2022)

Research on Ecological Security of Shengjin Lake Wetland (Anhui Province of China) Based on TM Images - Zhili Xu; Bin Dong; Xiang Gao; Ping Wang; Qing Wang; Sheng Li; Haifeng Xu; Yaru Liu; Tong Wang; Chunqiu Ren (Journal of the Indian Society of Remote Sensing, 2022)

Effects of nitrogen source and NaCl stress on oil production in Vischeria sp. WL1 (Eustigmatophyceae) isolated from dryland biological soil crusts in China - Yang She; Xiang Gao; Xin Jing; Jing Wang; Yibei Dong; Jinzi Cui; Huidan Xue; Zhengke Li; Derui Zhu (Journal of Applied Phycology, 2022)

Organophosphate esters in children and adolescents in Liuzhou city, China: concentrations, exposure assessment, and predictors - Meng Yu; Xiang Li; Bingqing Liu; Yaping Li; Ling Liu; Limei Wang; Lulu Song; Youjie Wang; Liqin Hu; Surong Mei (Environmental Science and Pollution Research, 2022)

Effect of electronic cigarette and tobacco smoking on the human saliva microbial community - Xue Wang; Qili Mi; Ji Yang; Ying Guan; Wanli Zeng; Haiying Xiang; Xin Liu; Wenwu Yang; Guangyu Yang; Xuemei Li; Yinshan Cui; Qian Gao (Brazilian Journal of Microbiology, 2022)

FLO8 deletion leads to decreased adhesion and virulence with downregulated expression of EPA1, EPA6, and EPA7 in Candida glabrata - Jun-Tao Zhao; Ke-Zhi Chen; Jin-Yan Liu; Wei-Hua Li; Yu-Zhu Wang; Lu-Ling Wang; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2022)

Plankton Metabolism in Coastal Waters of the Guangdong-Hong Kong-Macao Greater Bay: Regional Variance and Driving Factors - Liangkui Zhang; Gang Li; Chenhui Xiang; Yadong Huang; Xiaoming Fu; Chuanyang Zheng; Zheng Wang; Zhiyuan Ouyang; Xingyu Song (Frontiers in Marine Science, 2022)
Metabolisms of field plankton community, including gross primary production (GPP), community respiration (CR), and net community production (NCP), usually indicate the status of the health, resource production, and carbon budget of marine ecosystems. In this study, we explored the regional variance and driving forces of plankton metabolism in coastal waters of the Guangdong-Hong Kong-Macao Greater Bay Area (GGBA), a fast-developed area with complex hydrological and environmental states. The results showed that the maximum GPP and CR occurred in the estuarine plume of the GGBA in summer, while in winter the more active metabolisms of plankton community occurred in the Daya Bay, with the GPP and CR being respectively mediated by the nutrient level and temperature. Moreover, four regional zones were divided on the base of the environments and biological factors in surface water of the GGBA i.e., the river-runoff zone, river-plume zone, nearshore and far-offshore zones. The metabolic states in these zones varied significantly due to the regional and seasonal variations of, for example, the nutrient level, temperature, and turbidity driven by multiple factors including land-derived runoffs, anthropogenic activities, the Yuedong Coastal Current, and offshore seawater-intrusions. On the whole, the GGBA areas exhibited the weak heterotrophic processes in both summer (NCP = -24.9 ± 26.7 mg C m -3 d -1 ) and winter (NCP = -51.2 ± 8.51 mg C m -3 d -1 ). In addition, we found that the higher CR occurred to the bottom layers of the river plume and nearshore zones wherein hypoxia happened, indicating a possible attribution of plankton community respiration to the hypoxia in the GGBA.

Development and characterization of 123 SNPs in an endangered fish Semilabeo obscurus - Shikai Li; Wei Wang; Mingju Yang; Fujiang Huang; Xue Wang; Sheng Zeng; Yan Xiang; Lu Zhou (Conservation Genetics Resources, 2022)

Secoiridoid glycosides from the fruits of Cornus officinalis - Xin Wang; Xiang-Jian Zhong; Na Zhou; Lin-Lin Ji; Jin-Jie Li; Ning Cai; Qing-Bo Wang; Peng-Cheng Lin; Xiao-Ya Shang (Natural Product Research, 2022)

Improved Process Management of Glacial Lake Outburst Flood Hazards by Integrating Modular Monitoring, Assessment, and Simulation - Xiang Wang; Guo Chen; Xiaoai Dai; Jingjing Zhao; Xian Liu; Yu Gao; Junmin Zhang; Yongjun Chen; Xiaozhen Li; Wenyi Qin; Peng Wang (Water Resources Management, 2022)

Ventromedial Thalamus-Projecting DCN Neurons Modulate Associative Sensorimotor Responses in Mice - Jie Zhang; Hao Chen; Li-Bin Zhang; Rong-Rong Li; Bin Wang; Qian-Hui Zhang; Liu-Xia Tong; Wei-Wei Zhang; Zhong-Xiang Yao; Bo Hu (Neuroscience Bulletin, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

Combined effects of air pollution in adulthood and famine exposure in early life on type 2 diabetes - Wenqian Huo; Jian Hou; Luting Nie; Zhenxing Mao; Xiaotian Liu; Gongbo Chen; Hao Xiang; Shanshan Li; Yuming Guo; Chongjian Wang (Environmental Science and Pollution Research, 2022)

Responses of photosynthesis, antioxidant enzymes, and related gene expression to nicosulfuron stress in sweet maize (Zea mays L.) - Zhen-Xing Wu; Ning-Wei Xu; Min Yang; Xiang-Ling Li; Jin-Ling Han; Xiao-Hu Lin; Qing Yang; Gui-Hua Lv; Jian Wang (Environmental Science and Pollution Research, 2022)

Reduced Serum Magnesium Levels Are Associated with the Occurrence of Retinopathy in Patients with Type 2 Diabetes Mellitus: a Retrospective Study - Baodi Xing; Xiang Xu; Chengqian Li; Yuhang Zhao; Yangang Wang; Wenjuan Zhao (Biological Trace Element Research, 2022)

Study on shear behavior of coral reef limestone–concrete interface - De-jie Li; Chong Shi; Huai-ning Ruan; Bing-yi Li; Wang-yang Li; Xiang-chuan Yao (Marine Georesources & Geotechnology, 2022)

Genetic Diversity Analysis of Sugarcane (Saccharum spp. hybrids) Among High-Sucrose Clones of GT Series and Commonly Used Parents by Using Microsatellite Markers in Guangxi, China - Hai-Rong Huang; Yi-Jing Gao; Mukesh Kumar Malviya; Krishan K. Verma; Manoj Kumar Solanki; Yu-Xin Huang; Xiang Li; Yuchi Deng; Jing Yan; Shi-Yun Tang; Lun-Wang Wang; Lin Xu (Sugar Tech, 2022)

Prenatal Isoflurane Exposure Induces Developmental Neurotoxicity in Rats: the Role of Gut Microbiota - Li-Kuan Wang; Xu-Dong Yang; Dan Zhou; Tong Cheng; Xiang Zhang; Hai-Yin Wu (Neurotoxicity Research, 2022)

Water splitting, pollutant degradation and environmental impact using low-index faceted metal-based nanocrystals. A review - Xiang Zhang; Jie Tang; Nali Zhu; Lingxiangyu Li; Yawei Wang (Environmental Chemistry Letters, 2022)

Modular-level alterations of single-subject gray matter networks in schizophrenia - Yuxiang Guo; Yunxiao Ma; GongShu Wang; Ting Li; Tong Wang; Dandan Li; Jie Xiang; Tianyi Yan; Bin Wang; Miaomiao Liu (Brain Imaging and Behavior, 2022)

The Predictability of Ocean Environments that Contributed to the 2020/21 Extreme Cold Events in China: 2020/21 La Niña and 2020 Arctic Sea Ice Loss - Fei Zheng; Ji-Ping Liu; Xiang-Hui Fang; Mi-Rong Song; Chao-Yuan Yang; Yuan Yuan; Ke-Xin Li; Ji Wang; Jiang Zhu (Advances in Atmospheric Sciences, 2022)
Several consecutive extreme cold events impacted China during the first half of winter 2020/21, breaking the low-temperature records in many cities. How to make accurate climate predictions of extreme cold events is still an urgent issue. The synergistic effect of the warm Arctic and cold tropical Pacific has been demonstrated to intensify the intrusions of cold air from polar regions into middle-high latitudes, further influencing the cold conditions in China. However, climate models failed to predict these two ocean environments at expected lead times. Most seasonal climate forecasts only predicted the 2020/21 La Niña after the signal had already become apparent and significantly underestimated the observed Arctic sea ice loss in autumn 2020 with a 1–2 month advancement. In this work, the corresponding physical factors that may help improve the accuracy of seasonal climate predictions are further explored. For the 2020/21 La Niña prediction, through sensitivity experiments involving different atmospheric–oceanic initial conditions, the predominant southeasterly wind anomalies over the equatorial Pacific in spring of 2020 are diagnosed to play an irreplaceable role in triggering this cold event. A reasonable inclusion of atmospheric surface winds into the initialization will help the model predict La Niña development from the early spring of 2020. For predicting the Arctic sea ice loss in autumn 2020, an anomalously cyclonic circulation from the central Arctic Ocean predicted by the model, which swept abnormally hot air over Siberia into the Arctic Ocean, is recognized as an important contributor to successfully predicting the minimum Arctic sea ice extent.

Apelin-13 attenuates early brain injury through inhibiting inflammation and apoptosis in rats after experimental subarachnoid hemorrhage - Xiaoyan Shen; Guiqiang Yuan; Bing Li; Cheng Cao; Demao Cao; Jiang Wu; Xiang Li; Haiying Li; Haitao Shen; Zhong Wang; Gang Chen (Molecular Biology Reports, 2022)

QTL mapping integrated with BSA-Seq analysis identifies a novel gene conferring resistance to brown planthopper from common wild rice (Oryza rufipogon Griff.) - Xuan Wang; Yue Han; Yue-xiong Zhang; Biao Deng; Bi-qiu Wu; Xin-ying Guo; Yu-fen Qin; Yao-yu Fang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Euphytica, 2022)

Biological monitoring and health assessment of 21 metal(loid)s in children and adolescents in Liuzhou City, Southwest China - Yaping Li; Yu Zhang; Meng Yu; Liqin Hu; Ting Zeng; Ling Liu; Limei Wang; Liangqiong Deng; Xiang Li; Ping Liu; Dingyuan Zeng; Surong Mei (Environmental Science and Pollution Research, 2022)

Potential Protective Effect of Riboflavin Against Pathological Changes in the Main Organs of Male Mice Induced by Fluoride Exposure - Xiang Li; Jie Yang; Chen Liang; Wei Yang; Qianlong Zhu; Huifeng Luo; Xueyan Liu; Jundong Wang; Jianhai Zhang (Biological Trace Element Research, 2022)

Vibrational and structural insight into silicate minerals by mid-infrared absorption and emission spectroscopies - Ying Zhu; Yanzhang Li; Hongrui Ding; Anhuai Lu; Yan Li; Xiang Ji; Yuanlong Zhang; Changqiu Wang (Physics and Chemistry of Minerals, 2022)

Load transfer laws of tensile anchors in rock masses with weak interlayers based on a shear-slipping updating model - Yan Wang; Xin Xiang; Chang-dong Li; Guo-qiang Zhu; Cheng-bin Song; Jin-ye Xian; Jia-jun Zhang (Journal of Mountain Science, 2022)

Characterization and genomic analysis of a Demerecviridae phage SP76 with lytic multiple-serotypes of Salmonella - Hui Wang; Yun Shen; Pei LI; Yuyi Xiao; Yanxiu Li; Xiapei Hu; Zhuohao Wang; Zile Cheng; Zitong Wang; Qingxin Liu; Si Qin; Xiang Huo; et al. (Archives of Microbiology, 2022)

Sediment Resuspension as a Major Contributor to Sinking Particles in the Northwestern South China Sea: Evidence From Observations and Modeling - Lihua Ran; Wentao Ma; Martin G. Wiesner; Yuntao Wang; Jianfang Chen; Lanlan Zhang; Zhi Yang; Jingjing Zhang; Hongliang Li; Jian Ren; Rong Xiang; Erick Fredj (Frontiers in Marine Science, 2022)
The lateral advection of sinking particles is a well-known phenomenon in the South China Sea (SCS) and has a significant impact on the estimation of the efficiency of the biological carbon pump. However, little is known about the sources and pathways of sinking particles. Here, we present benthic and freshwater diatom fluxes and relative abundances collected by a sediment trap deployed at a water depth of 1,000 m and more than 500 m above the seafloor in the northwestern SCS, indicating that laterally transported resuspended sediment accounts for a significant part of the particle flux to the deep sea. A Lagrangian particle tracking model (LPTM) revealed that the resuspended particles likely originated from the neighboring continental slope, approximately 12–145 km to the west of the study site. Sediment trap observations and the LPTM together indicated that the impact of resuspended sediment occurred mainly in the deep water, and especially strong sediment resuspension was related to summer monsoon-induced coastal upwelling. The results suggest that particle resuspension has an important impact on the biological pump as well as on paleoenvironmental reconstructions of the SCS.

Two new diterpenoids from Penicillium chrysogenum MT-12, an endophytic fungus isolated from Huperzia serrata - Bowen Qi; Fangfang Jia; Yuan Luo; Ning Ding; Sainan Li; Fanyu Shi; Yan Hai; Lili Wang; Zhi-Xiang Zhu; Xiao Liu; Pengfei Tu; She-Po Shi (Natural Product Research, 2022)

Autophagic degradation of the chloroplastic 2-phosphoglycolate phosphatase TaPGLP1 in wheat - Jiayao Ni; Yuru Li; Yue Xiang; Xiangyun Yang; Lei Jia; Jieyu Yue; Huazhong Wang (Plant Cell Reports, 2022)

Digoxin Ameliorates Glymphatic Transport and Cognitive Impairment in a Mouse Model of Chronic Cerebral Hypoperfusion - Jie Cao; Di Yao; Rong Li; Xuequn Guo; Jiahuan Hao; Minjie Xie; Jia Li; Dengji Pan; Xiang Luo; Zhiyuan Yu; Minghuan Wang; Wei Wang (Neuroscience Bulletin, 2022)

Extraction optimization, physicochemical characterization, and antioxidant activity of polysaccharides from Rhodosorus sp. SCSIO-45730 - Na Wang; Lumei Dai; Zishuo Chen; Tao Li; Jiayi Wu; Houbo Wu; Hualian Wu; Wenzhou Xiang (Journal of Applied Phycology, 2022)

Interaction quantitative modeling of mixed surfactants for synergistic solubilization by resonance light scattering - Minghui Xiang; Zhen Lu; Ziyin You; Xuechen Wang; Maofang Huang; Weixiong Xu; Hui Li (Environmental Science and Pollution Research, 2022)

Quantifying the human disturbance intensity of ecosystems and its natural and socioeconomic driving factors in urban agglomeration in South China - Xiaojun Wang; Guangxu Liu; Aicun Xiang; Salman Qureshi; Tianhang Li; Dezhuo Song; Churan Zhang (Environmental Science and Pollution Research, 2022)

Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function - Huijie Zhang; Jiawei Qin; Xinqiang Lan; Weirong Zeng; Jing Zhou; Tian-E Huang; Wan-Li Xiao; Qi-Quan Wang; Sujiao Sun; Weiting Su; Wenhui Nie; Shan Yang; et al. (Biogerontology, 2022)

The first feline immunodeficiency virus from Siberian tigers (Panthera tigris altaica) in northeastern China - Enqi Liu; Liying Ma; Shuping Huang; Dan You; Lijun Guo; Xiang Li; Haitao Xu; Dan Liu; Hongliang Chai; Yajun Wang (Archives of Virology, 2022)

Secondary metabolites isolated from Agrimonia pilosa Ledeb. - Hong-Rui Li; Yu-Kui Li; Jian Xiao; Cui Yang; Meng-Yuan Jiang; Kai Tian; Wei Wang; Yan-Hong Li; Xiang-Zhong Huang (Natural Product Research, 2022)

Effect of Sodium Salicylate on Calcium Currents and Exocytosis in Cochlear Inner Hair Cells: Implications for Tinnitus Generation - Ting Fan; Meng-Ya Xiang; Ruo-Qiao Zhou; Wen Li; Li-Qin Wang; Peng-Fei Guan; Geng-Lin Li; Yun-Feng Wang; Jian Li (Neuroscience Bulletin, 2022)

Paracoccus shandongensis sp. nov., Isolated from Activated Sludge - Xiao-Fan Gong; Fang Wang; Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Zong-Jun Du; Qiang Li (Current Microbiology, 2022)

Identification of bacterial blight resistance genes in rice landraces from Yunnan Province, China - Caimei Zhao; Fuyou Yin; Ling Chen; Dingqin Li; Suqin Xiao; Qiaofang Zhong; Bo Wang; Xue Ke; Jian Fu; Xiang Li; Yue Chen; Lingxian Wang; et al. (Australasian Plant Pathology, 2022)
Bacterial blight (BB), a serious bacterial disease caused by pathogen Xanthomonas oryzae pv. oryzae ( Xoo ) affects rice growth and yield. Yunnan Province is regarded as a center of rice diversity in China and indeed the world, and has abundant rice landrace resources, which may offer prospective candidate donors in rice improvement and breeding. In this study, a set of 200 rice landraces were evaluated to determine their resistance to 10 pathogenic Xoo strains resistance by the leaf-clipping method. The results indicated that the tested rice landraces had different resistance levels against different Xoo strains. Multiple comparisons showed that the Xoo strain PXO99 was virulent to the tested rice landraces. Sixty-six rice landraces conferred resistance against at least one Xoo strain. These resistant rice landraces screened were then performed the presence of 14 cloned BB resistance genes by closely linked molecular markers and designed specific primers. The results showed that none of these resistant accessions contained xa13 , Xa21 , Xa27 , and Xa45(t) homologous fragments, while 9, 24, 4, 7, 9, 15, 1, 5, 4 and 27 accessions contained Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa7 , Xa10 , Xa23 and xa25 homologous fragments, respectively. Sequence analysis further revealed that nucleotide variations around functional nucleotide polymorphisms region were observed within these accessions containing the Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa10 , Xa23 and xa25 homologous fragments. These results along with phenotypic resistance spectrum supported that these accessions carried nine resistance homologous genes. Only one accession (Qishanggu_Wenshan) carried the Xa7 resistance gene. We also found that some resistant rice landraces, especially Xilandigu_Baoshan, and Laoyaling_Lincang without the above resistance genes, which mediated broad spectrum resistance to multiple Xoo strains, were identified as potential sources for breeding rice lines resistance to BB.

Laser ablation inductively coupled plasma mass spectrometry analysis of Chinese lead-barium glass: combining multivariate kernel density estimation and maximum mean discrepancy to reinterpret the raw glass used for producing lead-barium glass - Qian Ma; Rui Wen; Yifan Yu; Long Wang; Man Li; Luwu Cai; Li Ping; Zhiqiang Zhao; Dong Wang; Xiang Wang; Ruoyu Shi; A. Mark Pollard (Archaeological and Anthropological Sciences, 2022)

Structures and biological evaluation of phenylpropanoid derivatives from Dendrobium Sonia - Bai-xiang Cai; Lei-xin Song; Hai-jun Hu; Zhu-zhen Han; Yue Zhou; Zheng-tao Wang; Li Yang (Natural Product Research, 2021)

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Hydrogen Sulfide–Phytohormone Interaction in Plants Under Physiological and Stress Conditions - Zhong-Guang Li; Ru-Hua Xiang; Jia-Qi Wang (Journal of Plant Growth Regulation, 2021)

Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology - Yuhong Zhang; Xu Chen; Qiqi Wang; Congcong Du; Wenbin Lu; Hong Yuan; Zhenzhen Zhang; Danqing Li; Xing Ling; Xiang Ren; Yang Zhao; Qi Su; et al. (Journal of Molecular Medicine, 2021)

Antimicrobial Natural Products Produced by Soil-Derived Fungus Penicillium cremeogriseum W1-1 - Xu-Yan Sang; Zhao-Jie Wang; Ya-Bin Yang; Yong-Liang Wang; Mei-Ling Xiang; Dou-Ying Zhu; Ying Zhou; Xiao-Dong Luo; Li-Xing Zhao (Indian Journal of Microbiology, 2021)

Seasonal fluctuation of aerosolization ratio of bioaerosols and quantitative microbial risk assessment in a wastewater treatment plant - Rui-ning Wang; Xiang Li; Cheng Yan (Environmental Science and Pollution Research, 2021)

Dissimilatory nitrate reduction and functional genes in two subtropical rivers, China - Binjie Zhao; Xinshuai Li; Yang Wang; Xiang Tan; Wenhua Qi; Hongran Li; Junwei Wei; Yong You; Wenjun Shi; Quanfa Zhang (Environmental Science and Pollution Research, 2021)

Musk secretion of endangered Alpine musk deer (Moschus chrysogaster): muscone content and the relationships to age, health, mating history and enclosure condition - Naixiu Yuan; Yuhong Qin; Jing Wang; Liquan Shen; Haoxiang Gao; Rongwei Xiang; Yinjiu Zhu; Yong Li; Mi Zhou; Shoulin Bai; Yan Sheng; Xiuxiang Meng (Biologia, 2021)

Effect of introducing amino acids into phenazine-1-carboxylic acid on phloem mobility - Yongtong Xiong; Xiang Zhu; Jinyu Hu; Yunping Wang; Xiaoying Du; Junkai Li; Qinglai Wu (Natural Product Research, 2021)

Remotely sensed short-term changes in noctilucent algae blooms in the Bohai Sea - Liang Ma; Yan Liu; Bowen Zhang; Lingxing Lu; Guangshun Sun; Dongxu Wang; Zihui Liu; Bing Li; Yu Wang; Yue Zhang; Ailian Hu; Xiang Yu (International Journal of Remote Sensing, 2021)

Removal of roosters alters the domestic phenotype and microbial and genetic profile of hens - Hai Xiang; Siyu Chen; Hui Zhang; Xu Zhu; Dan Wang; Huagui Liu; Jikun Wang; Tao Yin; Langqing Liu; Minghua Kong; Jian Zhang; Hua Li; et al. (Science China Life Sciences, 2021)

The Utility of Gordon’s Standard NIR Empirical Atmospheric Correction Algorithm for Unmanned Aerial Vehicle Imagery - Liang Ma; Yan Liu; Xiang Yu; Chao Zhan; Bowen Zhang; Lingxing Lu; Zihui Liu; Bing Li; Guangshun Sun; Qing Wang (Journal of the Indian Society of Remote Sensing, 2021)

A genome-wide association study of seed size, protein content, and oil content using a natural population of Sichuan and Chongqing soybean - Qingyuan He; Shihua Xiang; Huawei Yang; Wubin Wang; Yingjie Shu; Zhengpeng Li; Xiaoyan Yang; Songhua Wang (Euphytica, 2021)

Sediment Coarsening in Tidal Flats and Stable Coastline of the Abandoned Southern Yellow River Sub-Delta in Response to Fluvial Sediment Flux Decrease During the Past Decades - Lin Zeng; Chao Zhan; Qing Wang; Xianbin Liu; Longsheng Wang; Xueyan Li; Xin Wang; Xiang Yu; Jinzhi Zhang; Buli Cui (Frontiers in Marine Science, 2021)
Due to remarkable reduction of sediment supply, the vulnerability of Yellow River deltaic system increased and ecological impacts occurred to some extent. To have a comprehensive and quantitative understanding of the morphological evolution of deltas, surficial sediments of tidal flat along the abandoned southern Yellow River sub-delta and two adjacent coastal units were systematically collected and evaluated by grain-size analysis in the study. The results reveal that surficial sediments of the abandoned southern Yellow River sub-delta have been coarsening significantly since the 1980s, as characterized by a decrease in both the mud content and the clay/mud ratio. In particular, the transition from cohesive to non-cohesive sediment was completed between 2007 and 2013. With a sharp decrease in sediment flux from the Yellow River estuary, the flood currents from the submarine coastal slope carry few fine particles into the tidal zone, whereas the ebb currents with reverse direction remove some fine particles from the tidal flat. This is a major cause of sediment coarsening in the tidal flat. As sediment coarsening, the coastline of the abandoned southern Yellow River sub-delta has remained stable. The significant change in the grain size of the tidal flat surficial sediments may have a profound impact on the future coastal geomorphic evolution.

Pleosporalins H and I, two new heptaketides from the endophytic fungus Pleosporales sp. F46 by using OSMAC strategy - Hong-Xia Yang; Xiao-Ping Peng; Han Gao; Hui-Min Zhang; Zi-Ru Wang; Gang Li; Hong-Xiang Lou (Natural Product Research, 2021)

A widespread response of Gram-negative bacterial acyl-homoserine lactone receptors to Gram-positive Streptomyces γ-butyrolactone signaling molecules - Xiang Liu; Wenxi Wang; Junyue Li; Yue Li; Jihui Zhang; Huarong Tan (Science China Life Sciences, 2021)

New approaches for archaeal genome-guided cultivation - Yinzhao Wang; Yoichi Kamagata; Meng Li; Feifei Han; Fengping Wang; Xiang Xiao (Science China Earth Sciences, 2021)

Responses of leaf litter decomposability to nitrogen and phosphorus additions are associated with cell wall carbohydrate composition in a subtropical plantation - Xiang-Min Fang; Xiu-Lan Zhang; Ying-Ying Zong; Wen-Qing Li; Jian-Jun Li; Li-Ping Guo; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

Loss of MIC60 Aggravates Neuronal Death by Inducing Mitochondrial Dysfunction in a Rat Model of Intracerebral Hemorrhage - Ruming Deng; Wenjie Wang; Xiang Xu; Jiasheng Ding; Jiahe Wang; Siyuan Yang; Haiying Li; Haitao Shen; Xiang Li; Gang Chen (Molecular Neurobiology, 2021)

Comparison on characterization and antioxidant activity of exopolysaccharides from two Porphyridium strains - Wei-Nan Wang; Yi Li; Ying Zhang; Wen-Zhou Xiang; Ai-Fen Li; Tao Li (Journal of Applied Phycology, 2021)

Effects of acute hypoxia and reoxygenation on oxygen sensors, respiratory metabolism, oxidative stress, and apoptosis in hybrid yellow catfish “Huangyou-1” - Xueying Pei; Mingxu Chu; Peng Tang; Hongyan Zhang; Xinyu Zhang; Xiang Zheng; Jie Li; Jie Mei; Tao Wang; Shaowu Yin (Fish Physiology and Biochemistry, 2021)

Research on a new cationic polyacrylamide (CPAM) with a cationic microblock structure and its enhanced effect on sludge condition and dewatering - Yuning Chen; Xuhao Li; Wang Zizeng; Li Feng; Jiehong Xie; Zeluan Lin; Zhihong Xu; Bingzhi Liu; Xiang Li; Huaili Zheng (Environmental Science and Pollution Research, 2021)

Mercury sources and physicochemical characteristics in ice, snow, and meltwater of the Laohugou Glacier Basin, China - Rukumesh Paudyal; Shichang Kang; Junming Guo; Lekhendra Tripathee; Chhatra Mani Sharma; Jie Huang; Yang Li; Fangping Yan; Kun Wang; Jizu Chen; Xiang Qin; Mika Sillanpaa (Environmental Science and Pollution Research, 2021)

Resting-state abnormalities in functional connectivity of the default mode network in autism spectrum disorder: a meta-analysis - Qing Wang; Hua-Yun Li; Yun-Da Li; Ya-Ting Lv; Hui-Bin Ma; An-Feng Xiang; Xi-Ze Jia; Dong-Qiang Liu (Brain Imaging and Behavior, 2021)

Deep profile soil moisture distribution characteristics for different micro-topographies on the semi-arid Loess Plateau, China - Qing-ping Gou; Qing-ke Zhu; Yi-xuan Li; Xiang-lei Tian; Peng-xiang Wang; Yun-ling Xin; Shu-yuan Luo (Journal of Mountain Science, 2021)

Whole-exome sequencing identified a novel mutation in CHM of a Chinese family - Hui Tang; Jun Mao; Jingjing Xiang; Minjuan Liu; Haibo Li; Ting Wang (Journal of Genetics, 2021)

Decoupling between Oxygen and Radiogenic Isotopes: Evidence for Generation of Juvenile Continental Crust by Partial Melting of Subducted Oceanic Crust - Xuan-Ce Wang; Qiuli Li; Simon A. Wilde; Zheng-Xiang Li; Chaofeng Li; Kai Lei; Shao-Jie Li; Linlin Li; Manoj K. Pandit (Journal of Earth Science, 2021)

Correction to: A failure case study of tunnel water inrush source identified by statistical analysis model - Li-Gang Yuan; Xiao-Li Li; Xin Li; Yi-Lin Yu; Li-Guang Chen; Xian-Pan Xu; Xiang Wang (Arabian Journal of Geosciences, 2021)

Massilia cellulosiltytica sp. nov., a novel cellulose-degrading bacterium isolated from rhizosphere soil of rice (Oryza sativa L.) and its whole genome analysis - Chuanjiao Du; Chenxu Li; Peng Cao; Tingting Li; Dandan Du; Xiangjing Wang; Junwei Zhao; Wensheng Xiang (Antonie van Leeuwenhoek, 2021)

Genetic origin of gas and fluid from the mud volcanoes in the North Tianshan area in Xinjiang Province, NW China - Xiaoqi Gao; Yangyang Wang; Yujiang Li; Lishuang Guo; Yang Xiang; Yuhan Jiang (Carbonates and Evaporites, 2021)

Identification of a 193 bp promoter region of TaNRX1-D gene from common wheat that contributes to osmotic or ABA stress inducibility in transgenic Arabidopsis - Jie Cheng; Fan Wei; Mingfei Zhang; Nan Li; Tianqi Song; Yong Wang; Dongsheng Chen; Jishan Xiang; Xiaoke Zhang (Genes & Genomics, 2021)

A failure case study of tunnel water inrush source identified by statistical analysis model - Li-Gang Yuan; Xiao-Li Li; Xin Li; Yi-Lin Yu; Li-Gang Chen; Xian-Pan Xu; Xiang Wang (Arabian Journal of Geosciences, 2021)

The Initial Errors in the Tropical Indian Ocean that Can Induce a Significant “Spring Predictability Barrier” for La Niña Events and Their Implication for Targeted Observations - Qian Zhou; Wansuo Duan; Xu Wang; Xiang Li; Ziqing Zu (Advances in Atmospheric Sciences, 2021)

The biological and chemical contents of atmospheric particulate matter and implication of its role in the transmission of bacterial pathogenesis - Xianghe Zhang; Ziyun Li; Jiamin Hu; Lei Yan; Yanyan He; Xiang Li; Mingyu Wang; Xiaomin Sun; Hai Xu (Environmental Microbiology, 2021)
Summary Atmospheric particulate matter (APM) is an environmental hazard that endangers human health and causes a variety of diseases. In this work, the microbial community composition, chemical element composition and antimicrobial resistance gene (ARG) prevalence, along with their relationships with environmental parameters were analysed using APM samples collected in Jinan, China. Pathogenic Klebsiella and Aeromonas were found to be significantly correlated with PM 2.5 and temperature, suggesting their proliferation on APM. PM 2.5 and PM 10 have similar microbial community compositions but different chemical element compositions, suggesting they have different origins, which have little impact on microbial community structures. This finding, together with analysis of the timing of microbial community structure changes, suggests that microbial community composition is impacted by anthropic activities. Further investigations showed that rare metals including lanthanides are significantly negatively correlated with pathogens in APM, suggesting their inhibitory role. ARGs were observed for every class of antibiotic except for carbapenems in APM, suggesting high ARG prevalence in APM, and APM functions in transmission of antimicrobial resistance. Results obtained in this study suggest that APM can act as a transmission vehicle for pathogenic bacteria and ARGs and lead to the implication of a new transmission route for bacterial pathogenesis by APM.

Modulation of the 5-HT 3 A receptor current by desacylbaldrinal - Li-Xia Wang; Hu-Lan Chen; Hong-Ling Yan; Fei Tang; Hai Zhang; Hong-Xiang Li; Qiang Ye; Cheng Peng; Yu-Zhu Tan (Natural Product Research, 2021)

Corticosterone Can Be an Essential Stress Index in Channel Catfish (Ictalurus punctatus) - Kang Xiao; Xi Wang; Wen-Bin Liu; Ding-Dong Zhang; Xiang-Fei Li; Chun-Nuan Zhang; Wei-Hua Chen; Kenneth Prudence Abasubong; Guang-Zhen Jiang (Frontiers in Marine Science, 2021)
Although cortisol is considered the main glucocorticoid involved in regulating stress in fish by elevating the serum glucose, the presence of serum corticosterone and whether its level can be used as an indicator for fish stress activation and reflect the degree of fish stress remains to be determined. To comprehensively and accurately evaluate the performance of two glucocorticoids after stress, in this study, seven of the most common stressors (ammonia nitrogen, high-temperature, acid, alkali, Aeromonas hydrophila, and salinity) in aquaculture were selected. The levels of serum corticosterone, cortisol, and glucose were detected within 48 h, and then the dynamic changes were analyzed. In addition, the kidneys were collected to detect the expression of corresponding proteins involved in corticosterone and cortisol synthesis (3 β-HSD and CYP17A1) for further exploration. From the results obtained, the content of serum corticosterone was about 100 times higher than that of cortisol, and it was found that corticosterone and cortisol showed different dynamic changes within 48 h among the seven kinds of stress. In the subsequent detection of glucose, it was found that the dynamic shift in glucose was not consistent with the dynamic changes of corticosterone or cortisol entirely but seemed to be caused by the combination of the two. In the follow-up protein expression detection, we found that corticosterone seemed to respond to stress earlier. Therefore, it is concluded that the responses of corticosterone and cortisol to stress are independent, corticosterone may be more sensitive in the current seven acute stresses, and then they regulate glucose together to resist stress. The study aimed to fill the vacancy of corticosterone in fish research and provide a reference for the complete evaluation of fish stress degree.

A 24,482-bp deletion is associated with increased seed weight in Brassica napus L. - Xiaohui Zhang; Qiyang Huang; Pengfei Wang; Feiyang Liu; Mudan Luo; Xiang Li; Zhuanrong Wang; Lili Wan; Guangsheng Yang; Dengfeng Hong (Theoretical and Applied Genetics, 2021)

Design, synthesis, and anticancer activities of 8,9-substituted Luotonin A analogs as novel topoisomerase I inhibitors - Yuanhang Xiang; Haiping Li; Jun Wang; Xiaozhi Peng; Chunling Hu; Laichun Luo (Medicinal Chemistry Research, 2021)

The improvement of pore characteristics, remediation efficiency, and biotoxicity of petroleum-contaminated soil with the addition of bulking agent on field-scale biopile treatment - Jiaojiao Jiang; Shijie Wang; Li´ao Wang; Quanwei Lv; Yinghuan Yang; Kejin Chen; Lingyue Liu; Xiang Wang (Journal of Soils and Sediments, 2021)

Overexpression of MdPHR1 Enhanced Tolerance to Phosphorus Deficiency by Increasing MdPAP10 Transcription in Apple (Malus × Domestica) - Rui Li; Jian-Ping An; Chun-Xiang You; Xiao-Fei Wang; Yu-Jin Hao (Journal of Plant Growth Regulation, 2021)

Genetic diversity of potato virus Y potato isolates from Shandong province, China - Meng-Ao Jia; Lu Wang; Ji-Wu Zhang; Yu-Shuang Guo; Xiang-Dong Li; Yan-Ping Tian (Journal of Plant Pathology, 2021)

Removal of phosphorus and ammonium from municipal wastewater treatment plant effluent by manganese ore in a simulated constructed wetland - Yungui Li; Xueying Bai; Ruonan Ding; Wenxuan Lv; Ying Long; Liang Wei; Fachun Xiang; Rong Wang (Environmental Science and Pollution Research, 2021)

Correction to: High-Dose Aluminum Exposure Further Alerts Immune Phenotype in Aplastic Anemia Patients - Yao Zuo; Xiang Lu; Xiaochao Wang; Suren R. Sooranna; Liju Tao; Shiqiang Chen; Hongwen Li; Dan Huang; Guanye Nai; Hong Chen; Chunfeng Pan; Caihong Huang; et al. (Biological Trace Element Research, 2021)
The article High-Dose Aluminum Exposure Further Alerts Immune Phenotype in Aplastic Anemia Patients, written by Yao Zuo, Xiang Lu, Xiaochao Wang, Suren R. Sooranna, Liju Tao, Shiqiang Chen, Hongwen Li, Dan Huang, Guanye Nai, Hong Chen, Chunfeng Pan, Caihong Huang and Yanmin Pang.

Microbacterium helvum sp. nov., a novel actinobacterium isolated from cow dung - Xiao Li; Lida Zhang; Fuyan Huang; Junwei Zhao; Han Wang; Yanjie Jiao; Lulu Qian; Xiangjing Wang; Wensheng Xiang (Archives of Microbiology, 2021)

Paracoccus binzhouensis sp. nov., isolated from activated sludge - Fang Wang; Xiao-Fan Gong; Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Zong-Jun Du; Qiang Li (Archives of Microbiology, 2021)

Terpenoids from the South China Sea soft coral Sinularia multiflora - Zheng Wang; Ping-Lin Li; Xiang-Chao Luo; Qi Wang; Leen van Ofwegen; Xu-Li Tang; Guo-Qiang Li (Natural Product Research, 2021)

Lignin degradation by water buffalo - Qingbiao Xu; Huimin Zhong; Jiayan Zhou; Yong Wu; Zhenhua Ma; Liguo Yang; Zhen Wang; Chuqi Ling; Xiang Li (Tropical Animal Health and Production, 2021)

Spatiotemporal variation and predictability of vegetation coverage in the Beijing–Tianjin–Hebei metropolitan region, China - Xiang Yu; Jiancang Xie; Rengui Jiang; Yong Zhao; Fawen Li; Jichao Liang; Yinping Wang (Theoretical and Applied Climatology, 2021)

Short-term waterlogging-induced autophagy in root cells of wheat can inhibit programmed cell death - Li-Lang Zhou; Kai-Yue Gao; Li-Sha Cheng; Yue-Li Wang; Yi-Keng Cheng; Qiu-Tao Xu; Xiang-Yi Deng; Ji-Wei Li; Fang-Zhu Mei; Zhu-Qing Zhou (Protoplasma, 2021)

Distinctive distributions of halophilic Archaea across hypersaline environments within the Qaidam Basin of China - Derui Zhu; Guoping Shen; Zhibo Wang; Rui Han; Qifu Long; Xiang Gao; Jiangwa Xing; Yongzhen Li; Rong Wang (Archives of Microbiology, 2021)

Neurovascular Units and Neural-Glia Networks in Intracerebral Hemorrhage: from Mechanisms to Translation - Qing Sun; Xiang Xu; Tianyi Wang; Zhongmou Xu; Xiaocheng Lu; Xiang Li; Gang Chen (Translational Stroke Research, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Galectin-9 Promotes Neuronal Restoration via Binding TLR-4 in a Rat Intracerebral Hemorrhage Model - Tianyu Liang; Cheng Ma; Tianyi Wang; Ruming Deng; Jiasheng Ding; Wenjie Wang; Zhongmou Xu; Xiang Li; Haiying Li; Qing Sun; Haitao Shen; Zhong Wang; et al. (NeuroMolecular Medicine, 2021)

Correction to: Sex-Specific Transcriptome Sequencing of Zoea I Larvae and Identification of Sex-Linked Genes Using Bulked Segregant Analysis in Pacific White Shrimp Litopenaeus vannamei - Yue Wang; Yang Yu; Shihao Li; Xiaojun Zhang; Jianhai Xiang; Fuhua Li (Marine Biotechnology, 2021)

Effects of Tobacco Stem-Derived Biochar on Soil Properties and Bacterial Community Structure under Continuous Cropping of Bletilla striata - Linyan Zhao; Huilin Guan; Rui Wang; Haoji Wang; Zecheng Li; Wei Li; Ping Xiang; Wumei Xu (Journal of Soil Science and Plant Nutrition, 2021)

Quantitative Evaluation of the Larval Density of Sea Potato Acaudina spp. with Mitochondrial Molecular Marker - Xiang Li; Guilin Wang; Yunfan Li; Wei Liu; Chao Lu; Yuchen Guo; Wen Huang; Jinhui Wang; Bo Dong (Journal of Ocean University of China, 2021)

Desorption hysteresis of coalbed methane and its controlling factors: a brief review - Weikai Xu; Junhui Li; Xiang Wu; Du Liu; Zhuangsen Wang (Frontiers of Earth Science, 2021)

Design of supercontinuum laser hyperspectral light detection and ranging (LiDAR) (SCLaHS LiDAR) - Guoqing Zhou; Xiang Zhou; Youjian Song; Donghui Xie; Long Wang; Guangjian Yan; Minglie Hu; Bowen Liu; Weidong Shang; Chenghu Gong; Cheng Wang; Huaguo Huang; et al. (International Journal of Remote Sensing, 2021)

Taste Masking Study Based on an Electronic Tongue: the Formulation Design of 3D Printed Levetiracetam Instant-Dissolving Tablets - Zengming Wang; Jingru Li; Xiaoxuan Hong; Xiaolu Han; Boshi Liu; Xianfu Li; Hui Zhang; Jing Gao; Nan Liu; Xiang Gao; Aiping Zheng (Pharmaceutical Research, 2021)
Purpose Proper taste-masking formulation design is a critical issue for instant-dissolving tablets (IDTs). The purpose of this study is to use the electronic tongue to design the additives of the 3D printed IDTs to improve palatability. Methods A binder jet 3D printer was used to prepare IDTs of levetiracetam. A texture analyzer and dissolution apparatus were used to predict the oral dispersion time and in vitro drug release of IDTs, respectively. The palatability of different formulations was investigated using the ASTREE electronic tongue in combination with the design of experiment and a model for masking bitter taste. Human gustatory sensation tests were conducted to further evaluate the credibility of the results. Results The 3D printed tablets exhibited rapid dispersion (<30 s) and drug release (2.5 min > 90%). The electronic tongue had an excellent ability of taste discrimination, and levetiracetam had a good linear sensing performance based on a partial least square regression analysis. The principal component analysis was used to analyze the signal intensities of different formulations and showed that 2% sucralose and 0.5% spearmint flavoring masked the bitterness well and resembled the taste of corresponding placebo. The results of human gustatory sensation test were consistent with the trend of the electronic tongue evaluation. Conclusions Owing to its objectivity and reproducibility, this technique is suitable for the design and evaluation of palatability in 3D printed IDT development.

Resolvin D1 Attenuates Innate Immune Reactions in Experimental Subarachnoid Hemorrhage Rat Model - Guang-Jie Liu; Tao Tao; Xiang-Sheng Zhang; Yue Lu; Ling-Yun Wu; Yong-Yue Gao; Han Wang; Hai-Bin Dai; Yan Zhou; Zong Zhuang; Chun-Hua Hang; Wei Li (Molecular Neurobiology, 2021)

Di-(2-ethylhexyl) phthalate induces testicular endoplasmic reticulum stress and germ cell apoptosis in adolescent mice - Bin-Bin Zhu; Zhi-Cheng Zhang; Jian Li; Xing-Xing Gao; Yuan-Hua Chen; Hua Wang; Lan Gao; De-Xiang Xu (Environmental Science and Pollution Research, 2021)

High-Dose Aluminum Exposure Further Alerts Immune Phenotype in Aplastic Anemia Patients - Yao Zuo; Xiang Lu; Xiaochao Wang; Suren R. Sooranna; Liju Tao; Shiqiang Chen; Hongwen Li; Dan Huang; Guanye Nai; Hong Chen; Chunfeng Pan; Caihong Huang; et al. (Biological Trace Element Research, 2021)
This study explored the relationship between immunological status and clinical characteristics of aplastic anemia (AA) patients to plasma aluminum levels, which were increased after constant exposure to high levels of this metal. Sixty-two AA patients (33 cases with high and 29 cases with low or no exposure to aluminum) and 30 healthy controls were selected for this study. Aluminum in human albumin solution was measured by inductivity coupled plasma mass spectrometry. IL-10, IL-12, IL-17, and INF-γ levels were measured by enzyme-linked immunosorbent assay. The distribution of lymphocyte subsets were determined by flow cytometry. The expression levels of immunoglobulins and complement C3 and C4 were also measured. Exposure to high aluminum raised the levels of serum aluminum in AA patients ( P < 0.01). The levels of hemoglobin and complement C4 were lower in AA patients with high aluminum exposure ( P < 0.05 and < 0.01, respectively). The percentage of CD4 + T cells and the ratio of CD4 + / CD8 + T cells in peripheral blood in AA patients with high aluminum exposure were higher compared with control AA patients ( P < 0.05 in both cases), while the percentage of CD8 + T cells was significantly lower than that in non-aluminum–exposed AA patients ( P < 0.05). Compared with non-aluminum–exposed AA patients, the level of IL-10 in the high aluminum–exposed AA group was significantly higher ( P < 0.05 in both cases). The immunological and clinical characteristics of AA patients from regions of high aluminum exposure are different to those in from non-aluminum areas. These results suggest that high aluminum exposure alters the immune system in patients suffering from AA.

Herbidospora solisilvae sp. nov., a novel cellulose-degrading actinobacterium isolated from forest soil - Mingying Yu; Rui Zhou; Jingjing Li; Liyuan Han; Han Wang; Siyu Zhang; Junwei Zhao; Xiangjing Wang; Jia Song; Wensheng Xiang (Antonie van Leeuwenhoek, 2021)

Comparison of Metabolic Profiling of Arabidopsis Inflorescences Between Landsberg erecta and Columbia, and Meiosis-Defective Mutants by 1H-NMR Spectroscopy - Xiang Li; Hongkuan Wang; Ying Wang; Limin Zhang; Yingxiang Wang (Phenomics, 2021)

Co-production of Tight Gas and Coalbed Methane from Single Wellbore: a Simulation Study from Northeastern Ordos Basin, China - Shihu Zhao; Yanbin Wang; Yong Li; Xiang Wu; Yinjie Hu; Xiaoming Ni; Du Liu (Natural Resources Research, 2021)

Whole-Genome Re-sequencing and Transcriptome Reveal Oogenesis-Related Genes in Autotetraploid Carassius auratus - Chongqing Wang; Huan Qin; Chun Zhao; Li Yang; Tingting Yu; Yuxin Zhang; Xiang Luo; Qinbo Qin; Shaojun Liu (Marine Biotechnology, 2021)

Marinobacter shengliensis subsp. alexandrii Subsp. Nov., Isolated from Cultivable Phycosphere Microbiota of Highly Toxic Dinoflagellate Alexandrium catenella LZT09 and Description of Marinobacter shengliensis Subsp. shengliensis Subsp. Nov - Xi Yang; Rong Xiang; Nurhezreen Md Iqbal; Yu-Han Duan; Xiao-Ai Zhang; Lei Wang; Lin-Zeng Yu; Jia-Zhou Li; Ming-Fei Sun; Qiao Yang; Chun-Tian Zheng; Shen-Quan Liao (Current Microbiology, 2021)

Abnormalities in hemispheric lateralization of intra- and inter-hemispheric white matter connections in schizophrenia - Dandan Li; Wenjing Tang; Ting Yan; Nan Zhang; Jie Xiang; Yan Niu; Bin Wang (Brain Imaging and Behavior, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

APOE ε4 and cognitive reserve effects on the functional network in the Alzheimer’s disease spectrum - Ting Li; Bin Wang; Yuan Gao; Xin Wang; Ting Yan; Jie Xiang; Yan Niu; Tiantian Liu; Duanduan Chen; Boyan Fang; Yunyan Xie; Shintaro Funahashi; et al. (Brain Imaging and Behavior, 2021)

Complex microbial communities inhabiting natural Cordyceps militaris and the habitat soil and their predicted functions - Xiao-Mei Zhang; De-Xiang Tang; Qing-Qing Li; Yuan-Bing Wang; Zhi-Hong Xu; Wen-Jun Li; Hong Yu (Antonie van Leeuwenhoek, 2021)

Three new sesquiterpenoids with cytotoxic activity from Artemisia argyi - Li Zhang; Yong-Ming Yan; Shao-Xiang Wang; Zhe Ren; Yong-Xian Cheng (Natural Product Research, 2021)

New equation to decipher the relationship between carbon isotopic composition of methane and maturity of gas source rocks - Jianping Chen; Xulong Wang; Jianfa Chen; Yunyan Ni; Baoli Xiang; Fengrong Liao; Wenjun He; Limiao Yao; Erting Li (Science China Earth Sciences, 2021)

Prevalence of obesity and clinical and metabolic correlates in first-episode schizophrenia relative to healthy controls - Yang Tian; Dongmei Wang; Gaoxia Wei; Jiesi Wang; Huixia Zhou; Hang Xu; Qilong Dai; Meihong Xiu; Dachun Chen; Li Wang; Xiang Yang Zhang (Psychopharmacology, 2021)

Litter addition and understory removal influenced soil organic carbon quality and mineral nitrogen supply in a subtropical plantation forest - Xiang-Min Fang; G. Geoff Wang; Zhi-Jun Xu; Ying-Ying Zong; Xiu-Lan Zhang; Jian-Jun Li; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

Snapshot of the Pliocene environment of West Kunlun region, Northwest China - Jia Liu; Teng-Xiang Wang; Xin-Wen Zhang; Ai Song; Shu-Feng Li; Jian Huang; Teresa Spicer; Robert A. Spicer; Fei-Xiang Wu; Tao Su; Zhe-Kun Zhou (Palaeobiodiversity and Palaeoenvironments, 2021)

Groundwater sources, flow patterns, and hydrochemistry of the Central Yinchuan Plain, China - Ying Li; Ping Wu; Xiao-Qin Huang; Bo Zhang; Zhao-Xiang Xu; Yang Li; Jie Li; Lu-Chen Wang; Yu-Fang Sun; Xu-Chen Meng; Cheng-Wen Wang; Zi-Zhao Cai (Hydrogeology Journal, 2021)

Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China - Qing-Hai Wang; Xiang-Ying Li; Ting-Ting Xu; Meng-Ai Zhang; Yu-Hui Yang; Pei-Bo Feng; Su-Su Fan; Zhen-Yu Liu (Journal of General Plant Pathology, 2021)

Propylenella binzhouense gen. nov., sp. nov. isolated from activated sludge, and proposal of Propylenellaceae fam. nov. - Yu-Ling Liu; Dong Meng; Fang Wang; Xiao-Fan Gong; Peng-Fei Gu; Xiang-Yu Fan; Zong-Jun Du; Ji-Dong Zou; Qiang Li (Antonie van Leeuwenhoek, 2021)

Structure elucidation and NMR assignments of a new alkaloid from Panzerina lanata (L.) Soják - Genyu Li; Qinghu Wang; Xiang He; Wenqiang Bao; Biligetu Pa (Natural Product Research, 2021)

Modulation of evening complex activity enables north-to-south adaptation of soybean - Xiaolong Fang; Yapeng Han; Mengshi Liu; Jiacan Jiang; Xiang Li; Qichao Lian; Xianrong Xie; Yian Huang; Qibin Ma; Hai Nian; Ji Qi; Cunyi Yang; et al. (Science China Life Sciences, 2021)

A Rehmannia glutinosa cinnamate 4-hydroxylase promotes phenolic accumulation and enhances tolerance to oxidative stress - Yan Hui Yang; Heng Yang; Rui Fang Li; Cui Xiang Li; Lei Zeng; Chao Jie Wang; Na Li; Zhuang Luo (Plant Cell Reports, 2021)

Phosphorylation at S548 as a Functional Switch of Sterile Alpha and TIR Motif-Containing 1 in Cerebral Ischemia/Reperfusion Injury in Rats - Tao Xue; Qing Sun; Yijie Zhang; Xin Wu; Haitao Shen; Xiang Li; Jiang Wu; Haiying Li; Zhong Wang; Gang Chen (Molecular Neurobiology, 2021)

Expression of G9a in Auditory Cortex Is Downregulated in a Rat Model of Age-Related Hearing Loss - Qian Li; Yang-hong Xiang; Xiao-jun Liang; Yun Zhang; Peng-peng Zhao; Min Wang; Xiao-min Bao; Xian-bai Zhu; An-chun Deng (Journal of Molecular Neuroscience, 2021)

Compound heterozygous mutation of the ASXL3 gene causes autosomal recessive congenital heart disease - Fang Fu; Ru Li; Ting-ying Lei; Dan Wang; Xin Yang; Jin Han; Min Pan; Li Zhen; Jian Li; Fa-tao Li; Xiang-yi Jing; Dong-zhi Li; et al. (Human Genetics, 2021)

3,5,4′-Trimethoxy-trans-stilbene loaded microemulsion for cutaneous melanoma therapy by transdermal drug delivery - Jun-Yong Wu; Jia-Xin Cai; Yong-Jiang Li; Xiong-Bin Hu; Xin-Yi Liu; Jie-Min Wang; Tian-Tian Tang; Da-Xiong Xiang (Drug Delivery and Translational Research, 2021)

Identification and Partial Characterization of an Alanine Aminotransferase Gene CsAlaAT2 in Response to Shade in Tea (Camellia sinensis) - Jinhe Wang; Wenzhen Chen; Yuanda Li; Xiuxiu Zhao; Qinzheng Xiang; Min Li (Journal of Plant Biology, 2021)

Climate Services for Water Resource Management in China: The Case Study of Danjiangkou Reservoir - Yujie Wang; Xiang Li; Song Liu; Zhenyu Han; Lianchun Song; Zongjian Ke; Keyao Chen (Journal of Meteorological Research, 2021)

Insights into the aridification history of Central Asian Mountains and international conservation strategy from the endangered wild apple tree - Hong‐Xiang Zhang; Xiao‐Shuang Li; Jian‐Cheng Wang; Dao‐Yuan Zhang (Journal of Biogeography, 2021)
Aim Evolutionary processes of mountain plants in arid lands remain poorly understood. Here, we investigate population genomics of the endangered wild apple tree to interpret the effects of long‐term aridification on plant diversification and demographical history in Central Asian Mountains. Location The Tianshan Mountains, spanning north‐western China, Kazakhstan, Kyrgyzstan and Tajikistan. Taxon Malus sieversii (Rosaceae) Methods Using genome‐wide single nucleotide polymorphisms, we assessed genetic diversity and genetic structure of 15 populations across the species' range. Demographical history was simulated with approximate Bayesian computation and species distribution modelling. We used a general linear model to identify key environmental factors affecting population genetic diversity and structure. Results We separated the 15 populations into three groups: the eastern group of western Junggar Mountains in China; the central group of the Ili Valley, the Talas Alatau Mountains in Kazakhstan and Kyrgyzstan; and the western group of Tajikistan and the Dzungarian Alatau in Kazakhstan. Central populations had higher genetic diversity and effective population size than eastern and western populations. The three groups split at the late Miocene and subsequently experienced extensive admixture. We detected a significant pattern of isolation by distance, but not isolation by environment, among these populations. Population genetic diversity was significantly associated with longitudinal and current environmental gradients. Main conclusions Long‐term aridification promoted distribution fragmentation and plant lineage divergence of relict broad‐leaved forests in Central Asian Mountains. Both geographical isolation and environmental heterogeneity shaped spatial patterns in genetic variation among M. sieversii populations. To maintain genetic integrity, we propose the establishment of an international network for the conservation of this endangered wild apple tree.

Diverse phylogeny and morphology of magnetite biomineralized by magnetotactic cocci - Peiyu Liu; Yan Liu; Xiang Zhao; Andrew P. Roberts; Heng Zhang; Yue Zheng; Fuxian Wang; Lushan Wang; Nicolas Menguy; Yongxin Pan; Jinhua Li (Environmental Microbiology, 2021)
Summary Magnetotactic bacteria (MTB) are diverse prokaryotes that produce magnetic nanocrystals within intracellular membranes (magnetosomes). Here, we present a large‐scale analysis of diversity and magnetosome biomineralization in modern magnetotactic cocci, which are the most abundant MTB morphotypes in nature. Nineteen novel magnetotactic cocci species are identified phylogenetically and structurally at the single‐cell level. Phylogenetic analysis demonstrates that the cocci cluster into an independent branch from other Alphaproteobacteria MTB, that is, within the Etaproteobacteria class in the Proteobacteria phylum. Statistical analysis reveals species‐specific biomineralization of magnetosomal magnetite morphologies. This further confirms that magnetosome biomineralization is controlled strictly by the MTB cell and differs among species or strains. The post‐mortem remains of MTB are often preserved as magnetofossils within sediments or sedimentary rocks, yet paleobiological and geological interpretation of their fossil record remains challenging. Our results indicate that magnetofossil morphology could be a promising proxy for retrieving paleobiological information about ancient MTB.

Foundation species across a latitudinal gradient in China - Xiujuan Qiao; Jiaxin Zhang; Zhong Wang; Yaozhan Xu; Tianyang Zhou; Xiangcheng Mi; Min Cao; Wanhui Ye; Guangze Jin; Zhanqing Hao; Xugao Wang; Xihua Wang; et al. (Ecology, 2021)
Foundation species structure forest communities and ecosystems but are difficult to identify without long‐term observations or experiments. We used statistical criteria––outliers from size‐frequency distributions and scale‐dependent negative effects on alpha diversity and positive effects on beta diversity––to identify candidate foundation woody plant species in 12 large forest‐dynamics plots spanning 26 degrees of latitude in China. We used these data (1) to identify candidate foundation species in Chinese forests, (2) to test the hypothesis––based on observations of a midlatitude peak in functional trait diversity and high local species richness but few numerically dominant species in tropical forests––that foundation woody plant species are more frequent in temperate than tropical or boreal forests, and (3) to compare these results with data from the Americas to suggest candidate foundation genera in northern hemisphere forests. Using the most stringent criteria, only two species of Acer , the canopy tree Acer ukurunduense and the shrubby treelet Acer barbinerve , were identified in temperate plots as candidate foundation species. Using more relaxed criteria, we identified four times more candidate foundation species in temperate plots (including species of Acer , Pinus , Juglans , Padus , Tilia , Fraxinus , Prunus , Taxus , Ulmus , and Corlyus ) than in (sub)tropical plots (the treelets or shrubs Aporosa yunnanensis , Ficus hispida , Brassaiopsis glomerulata , and Orophea laui ). Species diversity of co‐occurring woody species was negatively associated with basal area of candidate foundation species more frequently at 5‐ and 10‐m spatial grains (scale) than at a 20‐m grain. Conversely, Bray‐Curtis dissimilarity was positively associated with basal area of candidate foundation species more frequently at 5‐m than at 10‐ or 20‐m grains. Both stringent and relaxed criteria supported the hypothesis that foundation species are more common in mid‐latitude temperate forests. Comparisons of candidate foundation species in Chinese and North American forests suggest that Acer be investigated further as a foundation tree genus.

Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex - Zhijun Zhang; Hongxing Zhang; Chun-Ming Xie; Meng Zhang; Yachen Shi; Ruize Song; Xiang Lu; Haisan Zhang; Kun Li; Bi Wang; Yongfeng Yang; Xianrui Li; et al. (Science China Life Sciences, 2021)

NEURO-LEARN: a Solution for Collaborative Pattern Analysis of Neuroimaging Data - Bingye Lei; Fengchun Wu; Jing Zhou; Dongsheng Xiong; Kaixi Wang; Lingyin Kong; Pengfei Ke; Jun Chen; Yuping Ning; Xiaobo Li; Zhiming Xiang; Kai Wu (Neuroinformatics, 2021)

A Novel Fluorescent Probe Based on Pyrazole-Pyrazoline for Fe (III) Ions Recognition - Ying-Peng Zhang; Xiang-Fang Li; Yun-Shang Yang; Jing-Li Wang; Yu-Chen Zhao; Ji-Jun Xue (Journal of Fluorescence, 2021)

An updated evaluation of the global mean land surface air temperature and surface temperature trends based on CLSAT and CMST - Qingxiang Li; Wenbin Sun; Xiang Yun; Boyin Huang; Wenjie Dong; Xiaolan L. Wang; Panmao Zhai; Phil Jones (Climate Dynamics, 2021)

Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-κB mediated acute lung inflammation in mice - Tiancong Ma; Xiang Wang; Liqiao Li; Bingbing Sun; Yifang Zhu; Tian Xia (Archives of Toxicology, 2021)

Microplastics and their potential effects on the aquaculture systems: a critical review - Aiguo Zhou; Yue Zhang; Shaolin Xie; Yuliang Chen; Xiang Li; Jun Wang; Jixing Zou (Reviews in Aquaculture, 2021)
According to the statistics, 8.3 billion metric tonnes of plastics have been produced since 1950s, which is far more than other synthetic materials and the annual production which are about 500 million tonnes per year at present. The production of plastics makes microplastics pollution extremely widespread distribution, which will have a lasting impact on the global environment, especially on the aquaculture systems. And the distribution of the microplastics is extremely imbalanced around the global waters. In the present review, we have summarized the development of aquaculture in the World and China based on the existing data sources. And the total aquaculture production of the World will over 90 million tonnes, which will exceed the capture production in 2020. Aquaculture products will become one of the most important sources of high‐quality protein. However, we found that many kinds of microplastics are detected and enriched in both farmed and captured species. Both endogenous and exogenous factors like the use of fishing plastic products, factory farming facility and equipment, natural and synthetic feed, animal health products, aquaculture fortifier and aquatic food additives make accumulation of microplastics easier. In addition, the safety of aquaculture products is closely related to human health because the residues of microplastics in fish leading to various potential hazards. In summary, this paper reviewed the relationship between microplastics and aquaculture, aimed at calling for the rational and restricted use of plastic products in the aquaculture ecosystems.

Isolation and characterisation of N-benzyl tadalafil as a novel adulterant in a coffee-based dietary supplement - Pei-Zhi Dong; Xiao-Pu Liu; Lu Zhang; Guo-Hua Shen; Zi-Long Wang; Guo-Wei Yang; Wei Li; Xin-Hua Xiang (Food Additives & Contaminants: Part A, 2020)

NAC103, a NAC family transcription factor, regulates ABA response during seed germination and seedling growth in Arabidopsis - Ling Sun; Li-Ping Liu; Ya-Zhen Wang; Lei Yang; Mei-Jing Wang; Jian-Xiang Liu (Planta, 2020)

Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway - Xiang-Sheng Zhang; Yue Lu; Tao Tao; Han Wang; Guang-Jie Liu; Xun-Zhi Liu; Cang Liu; Da-Yong Xia; Chun-Hua Hang; Wei Li (Molecular Neurobiology, 2020)

Clinical characteristics and plasma antibody titer of patients with COVID-19 in Zhejiang, China - Wei-ling Xiang; Jing-jing Cheng; Lian-peng Wu; Bing-yu Chen; Wen-xin Li; Dan-ying Qiu; Wei Zhang; Fei-hang Ge; Dong Chen; Zhen Wang (Journal of Zhejiang University-SCIENCE B, 2020)

Response of the Organic Carbon Fractions and Stability of Soil to Alpine Marsh Degradation in Zoige, East Qinghai-Tibet Plateau - Yulin Pu; Chun Ye; Shirong Zhang; Guiyin Wang; Sijia Hu; Xiaoxun Xu; Shuang Xiang; Ting Li; Yongxia Jia (Journal of Soil Science and Plant Nutrition, 2020)

α-Helical protein absorption at post-traumatic epileptic foci monitored by Fourier transform infrared mapping - Siyang Xiang; Dong Zhao; Hongxia Hao; Xu Wang; Ling Li; Tiantong Yang (Journal of Biosciences, 2020)

Ecological risk assessment of heavy metals in fish from the Dianchi Lake, China using the integrated biomarker response approach - Ying Gao; Li Fang; Qian Qian Xiang; Di Wang; Liu Yong Ding; Cheng Zhi Ding; Li Qiang Chen (Environmental Science and Pollution Research, 2020)

A novel high-performance CeO2-CuMn2O4 catalyst for toluene degradation - Ting Zhou; Aijuan Xie; Qing Wang; Xiang Li; Zerui Zhu; Wanqi Zhang; Yuwei Tao; Shiping Luo (Environmental Science and Pollution Research, 2020)

Endothelial progenitor cells as the target for cardiovascular disease prediction, personalized prevention, and treatments: progressing beyond the state-of-the-art - Fang Kou; Chao Zhu; Hongjiang Wan; Fulong Xue; Jianfeng Wang; Lijie Xiang; Jingan Li (EPMA Journal, 2020)

Correction to: The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans - Jin-Yan Liu; Bing Wei; Ying Wang; Ce Shi; Wen-Jing Li; Yue Zhao; Ling-Ning Meng; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2020)

The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans - Jin-Yan Liu; Bing Wei; Ying Wang; Ce Shi; Wen-Jing Li; Yue Zhao; Ling-Ning Meng; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2020)

Dynamic reconfiguration of functional brain networks supporting response inhibition in a stop-signal task - Bin Wang; Yaqing Hao; Qionghui Zhan; Shuo Zhao; Dandan Li; Sumaira Imtiaz; Jie Xiang; Jinglong Wu; Hidenao Fukuyama; Ting Yan (Brain Imaging and Behavior, 2020)

Do Supercontinent-Superplume Cycles Control the Growth and Evolution of Continental Crust? - Xuan-Ce Wang; Simon A. Wilde; Zheng-Xiang Li; Shaojie Li; Linlin Li (Journal of Earth Science, 2020)

Sulforaphane delays diabetes-induced retinal photoreceptor cell degeneration - Jinjuan Lv; Shuyin Bao; Tianhe Liu; Limin Wei; Dongming Wang; Weikang Ye; Nina Wang; Shiyu Song; Jiao Li; Maryam Chudhary; Xiang Ren; Li Kong (Cell and Tissue Research, 2020)

Characteristics of discontinuities in Heifangtai landslide area in Gansu, China - Bin Li; Qiang Xu; Qiang Cheng; Tian-Xiang Liu; Ming-Gao Tang; Guang Zheng; Hai-Yan Wang (Applied Geophysics, 2020)

Microbispora cellulosiformans sp. nov., a novel actinomycete with cellulase activity isolated from soil in the cold region - Xiujie Gong; Wensheng Xiang; Xu Cao; Yang Yu; Yubo Hao; Liang Li; Qiuju Wang; Hongtao Zou; Chunrong Qian (Antonie van Leeuwenhoek, 2020)

Distortion effects caused by target abnormal bodies in CSAMT exploration - Xian-Xiang Wang; Ju-Zhi Deng; Jing-Li Ren (Acta Geophysica, 2020)

Chemical compositions of sulfides in the porphyry Cu ores, Yangla Cu deposit, Yunnan, China: implication for ore genesis - Xinfu Wang; Bo Li; Zuopeng Xiang; Yan Yue; Guo Tang (Acta Geochimica, 2020)

Association of cigarette smoking with cognitive impairment in male patients with chronic schizophrenia - Shuochi Wei; Dongmei Wang; Gaoxia Wei; Jiesi Wang; Huixia Zhou; Hang Xu; Luyao Xia; Yang Tian; Qilong Dai; Rongrong Zhu; Wenjia Wang; Dachun Chen; et al. (Psychopharmacology, 2020)

Evolution mechanism study of flow slide catastrophes in large waste dumps at the Nanfen iron mine - Hai-bin Wang; Fei Yan; Xiao-chun Li; Zi-jun Mi; Xiang-ming Li; Shao-quan Wang (Bulletin of Engineering Geology and the Environment, 2020)

Mfsd2a Attenuates Blood-Brain Barrier Disruption After Sub-arachnoid Hemorrhage by Inhibiting Caveolae-Mediated Transcellular Transport in Rats - Chongshun Zhao; Junwei Ma; Zhong Wang; Haiying Li; Haitao Shen; Xiang Li; Gang Chen (Translational Stroke Research, 2020)

The role of Th17 cells in psoriasis - Binbin Li; Liangliang Huang; Peng Lv; Xiang Li; Ge Liu; Yan Chen; Ziyu Wang; Xiaoxian Qian; Yixiao Shen; Yunman Li; Weirong Fang (Immunologic Research, 2020)

Graph-based network analysis of resting-state fMRI: test-retest reliability of binarized and weighted networks - Jie Xiang; Jiayue Xue; Hao Guo; Dandan Li; Xiaohong Cui; Yan Niu; Ting Yan; Rui Cao; Yao Ma; Yanli Yang; Bin Wang (Brain Imaging and Behavior, 2020)

Sex Difference Between Trace Elements and Pulmonary Functions in Children - Zhenzhen Pan; Xiaojuan Zhang; Yu Hui; Hongxia Xiang; Qian Wang; Shiyao Xu; Ling Li (Biological Trace Element Research, 2020)

Evaluating Spatial Heterogeneity of Land Surface Hydrothermal Conditions in the Heihe River Basin - Yuan Zhang; Shaomin Liu; Xiao Hu; Jianghao Wang; Xiang Li; Ziwei Xu; Yanfei Ma; Rui Liu; Tongren Xu; Xiaofan Yang (Chinese Geographical Science, 2020)

An evaluation of the core bacterial communities associated with hypersaline environments in the Qaidam Basin, China - Derui Zhu; Rui Han; Qifu Long; Xiang Gao; Jiangwa Xing; Guoping Shen; Yongzhen Li; Rong Wang (Archives of Microbiology, 2020)

Evaluation and mining the applicable methods of roughage digestibility determination for buffalo (Bubalus bubalis) - Zhen Wang; Yong Wu; Liujie Shi; Luncheng Cui; Xiang Li; Changjiu He; Liguo Yang; Xiang Li (Tropical Animal Health and Production, 2020)

Prevalence of Autism Spectrum Disorder in China: A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years - Hao Zhou; Xiu Xu; Weili Yan; Xiaobing Zou; Lijie Wu; Xuerong Luo; Tingyu Li; Yi Huang; Hongyan Guan; Xiang Chen; Meng Mao; Kun Xia; et al. (Neuroscience Bulletin, 2020)

Roles of Prokineticin 2 in Subarachnoid Hemorrhage-Induced Early Brain Injury via Regulation of Phenotype Polarization in Astrocytes - Mian Ma; Haiying Li; Jiang Wu; Yunhai Zhang; Haitao Shen; Xiang Li; Zhong Wang; Gang Chen (Molecular Neurobiology, 2020)

Characterization and application of a putative transcription factor (SUT2) in Pichia pastoris - Yankun Yang; Yating Zheng; Pengcheng Wang; Xiang Li; Chunjun Zhan; Robert J. Linhardt; Fuming Zhang; Xiuxia Liu; Jinling Zhan; Zhonghu Bai (Molecular Genetics and Genomics, 2020)

Ectopic expression of an oat SnRK2 gene, AsSnRK2D, enhances dehydration and salinity tolerance in tobacco by modulating the expression of stress-related genes - Dian-Jun Xiang; Li-Li Man; Shuai Cao; Peng Liu; Zhi-Gang Li; Xiao-Dong Wang (Brazilian Journal of Botany, 2020)

Expression and evolution of the phospholipase C gene family in Brachypodium distachyon - Xianguo Wang; Yang Liu; Zheng Li; Xiang Gao; Jian Dong; Mingming Yang (Genes & Genomics, 2020)

Five new ent -kaurane diterpenes from Annona squamosa L. pericarps - Ya-Yun Chen; Cheng-Yao Ma; Mao-Lin Wang; Jia-Hui Lu; Peng Hu; Jian-Wei Chen; Xiang Li; Yong Chen (Natural Product Research, 2020)

CSF Brain-Reactive Autoantibodies are Elevated in Patients with Viral Encephalitis - Zhong-Yuan Yu; Jian-Hong Wang; Wei-Wei Li; Ye-Ran Wang; Noralyn B. Mañucat-Tan; Jun Wang; Ju Wang; Gao-Yu Cui; Jie-Xiang Pan; Shui-Xian Zhang; Zu-Juan Liu; Liang Tan; et al. (Neuroscience Bulletin, 2020)

The Polymorphism of LvMMD2 and Its Association with Growth Traits in Litopenaeus vannamei - Quanchao Wang; Yang Yu; Qian Zhang; Zheng Luo; Xiaojun Zhang; Jianhai Xiang; Fuhua Li (Marine Biotechnology, 2020)

Characteristics and Classification of the Geothermal Gradient in the Beijing–Tianjin–Hebei Plain, China - Xinwei Wang; Xiang Mao; Xiaoping Mao; Kewen Li (Mathematical Geosciences, 2020)

Discovering adventitious roots in Glycine tomentella Hayata: lack of adventitious roots as a morphological and taxonomic species indicator is worth considering - Zheng-Wei Zhang; Xiang-Hua Li; Xu-Dong Wang; Ke-Jing Wang (Genetic Resources and Crop Evolution, 2020)

Prenatal di-(2-ethylhexyl) phthalate maternal exposure impairs the spatial memory of adult mouse offspring in a phase- and gender-dependent manner - Ling-Li Zhao; Ru Shen; Cong-Cong Sun; Shan-Yu Zhang; Bo Wang; Mei-Fang Sun; De-Xiang Xu (Environmental Science and Pollution Research, 2020)

An Experimental Study on Scale-Dependent Velocity and Anisotropy in Fractured Media Based on Artificial Rocks with Controlled Fracture Geometries - Pinbo Ding; Ding Wang; Xiang-Yang Li (Rock Mechanics and Rock Engineering, 2020)

Light induces gene expression to enhance the synthesis of storage reserves in Brassica napus L. embryos - Helin Tan; Xiao Qi; Yan Li; Xingchun Wang; Jianguo Zhou; Xiuhong Liu; Xiaoli Shi; Wenxue Ye; Xiaoe Xiang (Plant Molecular Biology, 2020)

An improved gray Bernoulli model for estimating the relationship between economic growth and pollution emissions - Qin Li; Zheng-Xin Wang; Xiang-Yu Zhang (Environmental Science and Pollution Research, 2020)

Evoked-potential audiogram variability in a group of wild Yangtze finless porpoises (Neophocaena asiaeorientalis asiaeorientalis) - Zhi-Tao Wang; Jiao Li; Peng-Xiang Duan; Zhi-Gang Mei; Fu-Qiang Niu; Tomonari Akamatsu; Pei-Yu Lei; Lu Zhou; Jing Yuan; Yu-Wei Chen; Alexander Ya Supin; Ding Wang; et al. (Journal of Comparative Physiology A, 2020)

Serotonin-induced miR-221/222 contribute to the activation of hepatic stellate cells - Yi Xiang; Yu-Shui Ma; Ji-Bin Liu; Zhi-Jun Wu; Xiao-Ping Wang; Li-Ping Liu; Gao-Ren Wang; Da Fu; Wei Shi (Biologia, 2020)

Testing and constitutive modelling of the mechanical behaviours of gravelly soil material - Jiu-Chang Zhang; Yue Li; Bo Xu; Qin-Xiang Meng; Qiang Zhang; Ru-Bin Wang (Arabian Journal of Geosciences, 2020)

Formulation and Characterization of a 3D-Printed Cryptotanshinone-Loaded Niosomal Hydrogel for Topical Therapy of Acne - Zhuxian Wang; Li Liu; Shijian Xiang; Cuiping Jiang; Wenfeng Wu; Shifa Ruan; Qunqun Du; Tingting Chen; Yaqi Xue; Huoji Chen; Lidong Weng; Hongxia Zhu; et al. (AAPS PharmSciTech, 2020)

Sex-Specific Transcriptome Sequencing of Zoea I Larvae and Identification of Sex-Linked Genes Using Bulked Segregant Analysis in Pacific White Shrimp Litopenaeus vannamei - Yue Wang; Yang Yu; Shihao Li; Xiaojun Zhang; Jianhai Xiang; Fuhua Li (Marine Biotechnology, 2020)