Response of Soil Bacteria of Dicranopteris dichotoma Populations to Vegetation Restoration in Red Soil Region of China - Qi-yan Li; Chen-lu Zhu; Jun-bao Yu; Xin-yi Wu; Si-qi Huang; Fan Yang; Mulualem Tigabu; Xiao-long Hou (Journal of Soil Science and Plant Nutrition, 2023)

The Nasal Bacteria Microbiome Comparison Among Fungal Ball Sinusitis, Chronic Sinusitis with Polyps - Pengyu Shi; Hongzheng Wei; Xin Liu; Shouxiang Dong; Shuai He; Yun Zeng; Ting Yang; Chengyao Liu; Yunchuan Li (Indian Journal of Microbiology, 2023)

Whole exome sequencing improves genetic diagnosis of fetal clubfoot - Ruibin Huang; Hang Zhou; Chunling Ma; Fang Fu; Ken Cheng; You Wang; Ru Li; Tingying Lei; Qiuxia Yu; Dan Wang; Shujuan Yan; Xin Yang; et al. (Human Genetics, 2023)

Distribution patterns of landslides triggered by the 2022 Ms 6.8 Luding earthquake, Sichuan, China - Jian-qiang Zhang; Zong-ji Yang; Qing-kai Meng; Jiao Wang; Kai-heng Hu; Yong-gang Ge; Feng-huan Su; Bo Zhao; Bo Zhang; Ning Jiang; Yu Huang; Zai-yang Ming; et al. (Journal of Mountain Science, 2023)

Pipeline positioning by the surface-to-borehole electromagnetic induction method in a clayey deposit - Guo-Wei Li; Zhi-Ming Ye; Yang Zhou; Guan-Jun He; Guang-Yu Liu; Xin-Rong He (Applied Geophysics, 2023)

How has horizontal gene transfer shaped the evolution of insect genomes? - Chao Liu; Yang Li; Yun Chen; Xue‐xin Chen; Jianhua Huang; Antonis Rokas; Xing‐Xing Shen (Environmental Microbiology, 2023)
As the most diverse group of animals on Earth, insects are key organisms in ecosystems. Horizontal gene transfer (HGT) refers to the transfer of genetic material between species by non‐reproductive means. HGT is a major evolutionary force in prokaryotic genome evolution, but its importance in different eukaryotic groups, such as insects, has only recently begun to be understood. Genomic data from hundreds of insect species have enabled the detection of large numbers of HGT events and the elucidation of the functions of some of these foreign genes. Although quantification of the extent of HGT in insects broadens our understanding of its role in insect evolution, the scope of its influence and underlying mechanism(s) of its occurrence remain open questions for the field.

Research on Bearing Characteristics of Gravity Anchor in Clay - Jianxing Yu; Pengfei Liu; Yang Yu; Xin Liu; Haoda Li; Ruoke Sun; Xuyang Zong (Journal of Marine Science and Engineering, 2023)
The applications and studies of gravity anchors in the ocean are becoming more and more extensive. Most of the research, however, has been directed toward the bearing properties of sand. Relatively less attention has been paid to the bearing properties of gravity anchors in clay. Clay is widely distributed on the seabed. The research on the bearing capacity of gravity anchors in clay is of great significance for offshore oil exploitation. Therefore, the gravity anchor was investigated by conducting reduced-scale model tests, and the bearing process of gravity anchors in clay was simulated through a 3D finite element method. Model tests and numerical simulations were used to determine the capacity curve and the V-H failure envelope of gravity anchors in clay. The simulation results and the test results are in good agreement. The failure form of the gravity anchor in clay was revealed by 3D finite element analysis. The effect of cohesion, internal friction angle, and mooring point height on bearing capacity have been studied. The influence of the height of the mooring point on the V-H failure envelope curve was explored by changing the height of the mooring point. The formula of the V-H failure envelope curve suitable for different mooring point heights was obtained.

Assessing the effects of heavy metals and polycyclic aromatic hydrocarbons on benthic foraminifera: The case of Houshui and Yangpu Bays, Hainan Island, China - Muhui Zhang; Chupeng Yang; Guanqiang Cai; Shun Li; Xin Nie; Shuqin Zhou (Frontiers in Marine Science, 2023)
This work aimed to investigate the distribution of benthic foraminiferal assemblages in Houshui and Yangpu Bays, Hainan Island, and assess the relative effects of heavy metals, total organic carbon (TOC), and polycyclic aromatic hydrocarbons (PAHs) on foraminiferal assemblages. A total of 30 sites were sampled and analyzed for benthic foraminiferal assemblages, heavy metals, TOC, and PAHs. The organic matter in the study was derived primarily from algae according to the C/N ratios, and PAHs were generated by petroleum and combustion of petroleum products, as inferred from the diagnostic ratios of PAH isomers. Two-way hierarchical cluster analysis was used to classify the 35 common species into two species groups, and the 30 sites were classified based on their geographical location. CCA was used to investigate the effects of pollution on foraminiferal assemblages. The results showed that the effects of pollution on foraminiferal assemblages were in the order of heavy metals > TOC > PAHs. Furthermore, the species group I, which consisted of agglutinated taxa including Bigenerina nodosaria, Ammobaculites agglutinans, Textularia spp., T. foliacea, Haplophragmoides canariensis, and several tolerant species of hyaline forms, including Ammonia beccarii, Elphidium advenum, E. hispidulum, Quinqueloculina laevigata, and Q. seminula, was found to be positively influenced by heavy metals. In contrast, species group II, primarily composed of porcelaneous taxa such as Massilina laevigata, Spiroloculina communis, and some hyaline taxa including E. crispum and Elphidium spp., was found to be positively influenced by TOC and PAHs. This work suggest that heavy metal pollution is the main factor influencing foraminiferal assemblages in the study area. The observed positive effect of heavy metals on species group I may indicate the presence of metal-tolerant taxa, whereas the positive effect of TOC and PAHs on species group II suggests that these taxa may be more tolerant of organic pollution. The study highlights the potential of specific foraminiferal assemblages as bioindicators for assessing the impact of different types of pollution on marine ecosystems.

The short-term effects of air pollution exposure on preterm births in Chongqing, China: 2015–2020 - Xin Ming; Ziyi He; Yannan Li; Yaqiong Hu; Yunping Yang; Hongyan Chen; Qin Chen; Huan Yang; Wenzheng Zhou (Environmental Science and Pollution Research, 2023)
Accumulating evidence suggested that the risk of preterm births (PTBs) following prenatal exposure to air pollution was inconclusive. The aim of this study is to investigate the relationship between air pollution exposure in the days before delivery and PTB and assess the threshold effect of short-term prenatal exposure to air pollution on PTB. This study collected data including meteorological factors, air pollutants, and information in Birth Certificate System from 9 districts during 2015–2020 in Chongqing, China. Generalized additive models (GAMs) with the distributed lag non-linear models were conducted to assess the acute impact of air pollutants on the daily counts of PTB, after controlling for potential confounding factors. We observed that PM 2.5 was related to increased occurrence of PTB on lag 0–3 and lag 10–21 days, with the strongest on the first day (RR = 1.017, 95%CI: 1.000–1.034) and then decreasing. The thresholds of PM 2.5 for lag 1–7 and 1–30 days were 100 μg/m 3 and 50 μg/m 3 , respectively. The lag effect of PM 10 on PTB was very similar to that of PM 2.5 . In addition, the lagged and cumulative exposure of SO 2 and NO 2 was also associated with the increased risk of PTB. The lag relative risk and cumulative relative risk of CO exposure were the strongest, with a maximum RR at lag 0 (RR = 1.044, 95%CI: 1.018, 1.069). Importantly, the exposure–response curve of CO showed that RR increased rapidly when the concentration exceeded 1000 μg/m 3 . This study indicated significant associations between air pollution and PTB. The relative risk decreases with day lag, while the cumulative effect increases. Thus, pregnant women should understand the risk of air pollution and try to avoid high concentration exposure.

Integrating oculomics with genomics reveals imaging biomarkers for preventive and personalized prediction of arterial aneurysms - Yu Huang; Cong Li; Danli Shi; Huan Wang; Xianwen Shang; Wei Wang; Xueli Zhang; Xiayin Zhang; Yijun Hu; Shulin Tang; Shunming Liu; Songyuan Luo; et al. (EPMA Journal, 2023)
Objective Arterial aneurysms are life-threatening but usually asymptomatic before requiring hospitalization. Oculomics of retinal vascular features (RVFs) extracted from retinal fundus images can reflect systemic vascular properties and therefore were hypothesized to provide valuable information on detecting the risk of aneurysms. By integrating oculomics with genomics, this study aimed to (i) identify predictive RVFs as imaging biomarkers for aneurysms and (ii) evaluate the value of these RVFs in supporting early detection of aneurysms in the context of predictive, preventive and personalized medicine (PPPM). Methods This study involved 51,597 UK Biobank participants who had retinal images available to extract oculomics of RVFs. Phenome-wide association analyses (PheWASs) were conducted to identify RVFs associated with the genetic risks of the main types of aneurysms, including abdominal aortic aneurysm (AAA), thoracic aneurysm (TAA), intracranial aneurysm (ICA) and Marfan syndrome (MFS). An aneurysm-RVF model was then developed to predict future aneurysms. The performance of the model was assessed in both derivation and validation cohorts and was compared with other models employing clinical risk factors. An RVF risk score was derived from our aneurysm-RVF model to identify patients with an increased risk of aneurysms. Results PheWAS identified a total of 32 RVFs that were significantly associated with the genetic risks of aneurysms. Of these, the number of vessels in the optic disc (‘ntreeA’) was associated with both AAA ( β = −0.36, P = 6.75e−10) and ICA ( β = −0.11, P = 5.51e−06). In addition, the mean angles between each artery branch (‘curveangle_mean_a’) were commonly associated with 4 MFS genes ( FBN1 : β = −0.10, P = 1.63e−12; COL16A1 : β = −0.07, P = 3.14e−09; LOC105373592 : β = −0.06, P = 1.89e−05; C8orf81/LOC441376 : β = 0.07, P = 1.02e−05). The developed aneurysm-RVF model showed good discrimination ability in predicting the risks of aneurysms. In the derivation cohort, the C -index of the aneurysm-RVF model was 0.809 [95% CI: 0.780–0.838], which was similar to the clinical risk model (0.806 [0.778–0.834]) but higher than the baseline model (0.739 [0.733–0.746]). Similar performance was observed in the validation cohort, with a C -index of 0.798 (0.727–0.869) for the aneurysm-RVF model, 0.795 (0.718–0.871) for the clinical risk model and 0.719 (0.620–0.816) for the baseline model. An aneurysm risk score was derived from the aneurysm-RVF model for each study participant. The individuals in the upper tertile of the aneurysm risk score had a significantly higher risk of aneurysm compared to those in the lower tertile (hazard ratio = 17.8 [6.5–48.8], P = 1.02e−05). Conclusion We identified a significant association between certain RVFs and the risk of aneurysms and revealed the impressive capability of using RVFs to predict the future risk of aneurysms by a PPPM approach. Our finds have great potential to support not only the predictive diagnosis of aneurysms but also a preventive and more personalized screening plan which may benefit both patients and the healthcare system. Graphical abstract

Leaf spot of Ligustrum japonicum caused by Diaporthe eres newly reported in China - Yang-Chun-Zi Liao; Yu Wan; Yuan-Zhi Si; Ji-Xin Geng; De-Wei Li; Li-Hua Zhu (Crop Protection, 2023)

Fouling-free membrane stripping for ammonia recovery from real biogas slurry - Cong Chen; Zhinan Dai; Yifan Li; Qin Zeng; Yang Yu; Xin Wang; Changyong Zhang; Le Han (Water Research, 2023)

Latitudinal patterns of particulate and mineral-associated organic matter down the soil profile in drylands - Xiaojuan Li; Tinghui Yang; Lettice C. Hicks; Bin Hu; Fanglan Li; Xin Liu; Dandan Wei; Zilong Wang; Weikai Bao (Soil and Tillage Research, 2023)

Observation and modeling of organic nitrates on a suburban site in southwest China - Chunmeng Li; Haichao Wang; Xiaorui Chen; Tianyu Zhai; Xuefei Ma; Xinping Yang; Shiyi Chen; Xin Li; Limin Zeng; Keding Lu (Science of The Total Environment, 2023)

Preparation of water storage ceramsite via dredged silt and biomass waste: Pore formation, water purification and application - Li Xiangguo; Wang Weizhen; Jian Shouwei; Li Baodong; Gao Xin; Huang Jianxiang; Lv Yang (Science of The Total Environment, 2023)

Variation of the toxicity caused by key contaminants in industrial wastewater along the treatment train of Fenton-activated sludge-advanced oxidation processes - Xiaolin Li; Heyun Yang; Jian Pan; Tong Liu; Xin Cao; Hao Ma; Xingliang Wang; Yi-fan Wang; Yifan Wang; Sijia Lu; Jiayu Tian; Lei Gao; et al. (Science of The Total Environment, 2023)

Isolation and evaluation of antioxidants from Arisaema heterophyllum tubers - Na Sun; Huanhuan Yang; Miao Zhou; Yanyan Hou; Xinru Wu; Wenqian Li; Yifang Zhang; Jinge Sun; Xin Xiong; Jihong Huang; Penghua Shu (Phytochemistry Letters, 2023)

An antioxidant lignan glycoside and triterpenoid saponins from the leaves of Synsepalum dulcificum - Xin-Peng Li; Jun-Fei Wang; Rong Huang; Tang-Chang Xu; Si-Si Liu; Qing-Rong Yang; Shao-Hua Wu (Phytochemistry Letters, 2023)

Functional analysis of 3 genes in xenobiotic detoxification pathway of Bursaphelenchus xylophilus against matrine - Yang Li; Bi Wu; Xin Hao; Jian Diao; Jingxin Cao; Ruina Tan; Wei Ma; Ling Ma (Pesticide Biochemistry and Physiology, 2023)

Complete genome sequence of marine Roseobacter lineage member Ruegeria sp. YS9 with five plasmids isolated from red algae - Qun-Jian Yin; Fang-Chao Zhu; Hong-Zhi Tang; Xu-Yang Chen; Xin Liu; Li-Chang Tang; Xue-Gong Li (Marine Genomics, 2023)

Sonocatalytic removal of tetracycline in the presence of S-scheme Cu2O/BiFeO3 heterojunction: Operating parameters, mechanisms, degradation pathways and toxicological evaluation - Xin Wang; Xue-Song He; Chun-Yu Li; Shi-Lin Liu; Wen Lu; Zheng Xiang; Yang Wang (Journal of Water Process Engineering, 2023)

Applications of functional nanoparticle–stabilized surfactant foam in petroleum-contaminated soil remediation - Jia Liu; Wen-yan Li; Hong-xin Chen; Shuang-qiang Li; Li-heng Yang; Kai-ming Peng; Chen Cai; Xiang-feng Huang (Journal of Hazardous Materials, 2023)

Thiobacillus spp. and Anaeromyxobacter spp. mediate arsenite oxidation-dependent biological nitrogen fixation in two contrasting types of arsenic-contaminated soils - Yongbin Li; Lifang Guo; Rui Yang; Zhaohui Yang; Haihan Zhang; Qiqian Li; Zhiguo Cao; Xin Zhang; Pin Gao; Wenlong Gao; Geng Yan; Duanyi Huang; et al. (Journal of Hazardous Materials, 2023)

Quantitative assessment of the impact of biomass burning episodes on surface solar radiation using machine learning technology: A case study of a pollution event in Beijing - Zhigang Li; Xin Yang; Hong Tang; Shili Yang (Journal of Atmospheric and Solar-Terrestrial Physics, 2023)

Flow characteristics and phase transition of subcritical to supercritical kerosene injections in a convergent nozzle - Guigui Liu; Yuzhen Lin; Jiaju Li; Xin Xue; Xin Hui; Chih-Jen Sung; Yue Yang (Fuel, 2023)

Attrition and attrition-resistance of oxygen carrier in chemical looping process – A comprehensive review - Fang Liu; Chen Song; Dan Zhu; Caifu Li; Lun Ai; Chunmei Xin; Xingyang Zeng; Liang Zeng; Neng Huang; Li Yang (Fuel, 2023)

A review of potential antibacterial activities of nisin against Listeria monocytogenes: the combined use of nisin shows more advantages than single use - Mengjie Wu; Yue Ma; Xin Dou; Muhammad Zohaib Aslam; Yangtai Liu; Xuejuan Xia; Shuo Yang; Xiang Wang; Xiaojie Qin; Takashi Hirata; Qingli Dong; Zhuosi Li (Food Research International, 2023)

Changes in structural and functional properties of whey protein cross-linked by polyphenol oxidase - Ruoting Yang; Huming Shao; Yuting Yan; Yong Wu; Xuanyi Meng; Anshu Yang; Zhihua Wu; Jinyan Gao; Xin Li; Hongbing Chen (Food Research International, 2023)

A novel zein-selenium complex nanoparticle with controllable size: Quantitative design, physical properties and cytotoxicity in vitro - Hao Wang; Zi-Zi Li; Xiang-Yao Liang; Wen-Yi Jiang; Xin-Quan Yang; Qing-Zhu Zeng; Yang Yuan (Food Chemistry, 2023)

Orychophragmus violaceus/cotton relay intercropping with reduced N application maintains or improves crop productivity and soil carbon and nitrogen fractions - Zhenggui Zhang; Jian Wang; Shiwu Xiong; Weibin Huang; Xiaofei Li; Minghua Xin; Yingchun Han; Guoping Wang; Lu Feng; Yaping Lei; Beifang Yang; Yabing Li; et al. (Field Crops Research, 2023)

Resistance vs. surrender: Different responses of functional traits of soybean and peanut to intercropping with maize - Wei-Ping Zhang; Zhao-Xin Li; Sai-Nan Gao; Hao Yang; Hua-Sen Xu; Xin Yang; Hong-Xia Fan; Ye Su; Surigaoge; Jacob Weiner; Dario Fornara; Long Li (Field Crops Research, 2023)

Preparation of XCu@TiO2 adsorbent for high-efficient PH3 removal in anaerobic environment and evaluation of desulfurization activity of deactivated adsorbent - Lijuan Jia; Xuejin Yang; Kaiqiang Hu; Jiayu Feng; Fang Wang; Kai Li; Xin Sun; Fei Wang; Ping Ning (Chemical Engineering Journal, 2023)

High sensitivity tactile sensors with ultrabroad linear range based on gradient hybrid structure for gesture recognition and precise grasping - Shuai Wang; Zaoxu Zhang; Bin Yang; Xin Zhang; Huiming Shang; Li Jiang; Hong Liu; Jia Zhang; PingAn Hu (Chemical Engineering Journal, 2023)

Engineering electron redistribution of bimetallic phosphates with CeO2 enables high-performance overall water splitting - Xin Guo; Menggang Li; Longyu Qiu; Fenyang Tian; Lin He; Shuo Geng; Yequn Liu; Ying Song; Weiwei Yang; Yongsheng Yu (Chemical Engineering Journal, 2023)

High-level production of pullulan from high concentration of glucose by mutagenesis and adaptive laboratory evolution of Aureobasidium pullulans - Xiwen Li; Shuangzhi Zhao; Leilei Chen; Qingxin Zhou; Jiying Qiu; Xue Xin; Yanhao Zhang; Wei Yuan; Chengsen Tian; Jinyu Yang; Xiaobin Yu (Carbohydrate Polymers, 2023)

Water-borne, durable and multicolor silicon nanoparticles/sodium alginate inks for anticounterfeiting applications - Jing Xie; Xuening Sun; Xin Guo; Xiang Feng; Kailong Chen; Xin Shu; Chenhao Wang; Wei Sun; Yang Liu; Bin Shang; Xin Liu; Dongzhi Chen; et al. (Carbohydrate Polymers, 2023)

Community succession of microbial populations related to C N P S biological transformations regulates product maturity during cow-manure-driven composting - Xin Liu; Xiangmin Rong; Junyan Yang; Han Li; Wang Hu; Yong Yang; Guoliang Jiang; Rusheng Xiao; Xingxiang Deng; Guixian Xie; Gongwen Luo; Jiachao Zhang (Bioresource Technology, 2023)

Self-activation of potassium/iron citrate-assisted production of porous carbon/porous biochar composites from macroalgae for high-performance sorption of sulfamethoxazole - Jiacheng Qin; Rongting Ji; Qian Sun; Wei Li; Hu Cheng; Jiangang Han; Xin Jiang; Yang Song; Jianming Xue (Bioresource Technology, 2023)

Chronic hypoxia and Cu2+ exposure induce gill remodeling of largemouth bass through endoplasmic reticulum stress, mitochondrial damage and apoptosis - Qiao Liu; Hong Wang; Jiayu Ge; Lisen Li; Jie Luo; Kuo He; Haoxiao Yan; Xin Zhang; Rabia Tahir; Wei Luo; Shiyi Chen; Zhang Cheng; et al. (Aquatic Toxicology, 2023)

Different roles of primary and secondary sources in reducing PM2.5: Insights from molecular markers in Pearl River Delta, South China - Kong Yang; Duo-Hong Chen; Xiang Ding; Jun Li; Yu-Qing Zhang; Tao Zhang; Qiao-Yun Wang; Jun-Qi Wang; Qian Cheng; Hao Jiang; Ping Liu; Zi-Rui Wang; et al. (Atmospheric Environment, 2023)

A glyoxylate-containing benzene derivative and butenolides from a marine algicolous fungus Aspergillus sp. SCSIO 41304 - Xin Qi; Wei-Hao Chen; Xiu-Ping Lin; Sheng-Rong Liao; Bin Yang; Xue-Feng Zhou; Yong-Hong Liu; Jun-Feng Wang; Yong Li (Natural Product Research, 2023)

Collateral-Core Ratio as a Novel Predictor of Clinical Outcomes in Acute Ischemic Stroke - Jinhao Lyu; Sa Xiao; Zhihua Meng; Xiaoyan Wu; Wen Chen; Guohua Wang; Qingliang Niu; Xin Li; Yitong Bian; Dan Han; Weiting Guo; Shuai Yang; et al. (Translational Stroke Research, 2023)

Bcl10 phosphorylation-dependent droplet-like condensation positively regulates DNA virus-induced innate immune signaling - Dandan Yang; Gaofeng Pei; Shuangshuang Dong; Wenhao Zhang; Haiteng Deng; Xueqiang Zhao; Pilong Li; Xin Lin (Science China Life Sciences, 2023)

Elevated Levels of Naturally-Occurring Autoantibodies Against the Extracellular Domain of p75NTR Aggravate the Pathology of Alzheimer’s Disease - Chen-Yang He; Ding-Yuan Tian; Si-Han Chen; Wang-Sheng Jin; Yuan Cheng; Jia-Yan Xin; Wei-Wei Li; Gui-Hua Zeng; Cheng-Rong Tan; Jie-Ming Jian; Dong-Yu Fan; Jun-Rong Ren; et al. (Neuroscience Bulletin, 2023)

Continuous–Discontinuous Element Numerical Modeling of Damage and Fracture Characteristics of a Loaded Coal - Qi Zhang; Xiangchun Li; Biao Li; Yaoyu Shi; Xin Tian; Gang Yang (Natural Resources Research, 2023)

TREM2 and Microglia Contribute to the Synaptic Plasticity: from Physiology to Pathology - Chao-Ji Yu; Meng Wang; Rui-Yang Li; Tao Wei; Han-Chen Yang; Yun-Si Yin; Ying-Xin Mi; Qi Qin; Yi Tang (Molecular Neurobiology, 2023)

Chinese consensus guidelines for therapeutic drug monitoring of polymyxin B, endorsed by the Infection and Chemotherapy Committee of the Shanghai Medical Association and the Therapeutic Drug Monitoring Committee of the Chinese Pharmacological Society - Xiaofen Liu; Chenrong Huang; Phillip J. Bergen; Jian Li; Jingjing Zhang; Yijian Chen; Yongchuan Chen; Beining Guo; Fupin Hu; Jinfang Hu; Linlin Hu; Xin Li; et al. (Journal of Zhejiang University-SCIENCE B, 2023)

Exosomal miR-767 from senescent endothelial-derived accelerating skin fibroblasts aging via inhibiting TAB1 - Jing Li; Jiyong Tan; Qiong Song; Xinni Yang; Xin Zhang; Hao Qin; Gaoxiang Huang; Xiaoxue Su; Jing Li (Journal of Molecular Histology, 2023)
Skin aging is a complicated physiological process, and microRNA-mediated regulation has been shown to contribute to this process. Exosomes mediate intercellular communication through miRNAs, mRNAs and proteins, and participate in many physiological and pathological processes. Vascular endothelial cell-derived exosomes have been confirmed to be involved in the development of many diseases, however, their effects on skin aging have not been reported. In this study, senescent endothelial cells could regulate skin fibroblast functions and promote cell senescence through exosomal pathway. miR-767 was highly expressed in senescent vascular endothelial cells and their exosomes, and miR-767 is also upregulated in skin fibroblasts after treatment with exosomes derived from senescent vascular endothelial cells. In addition, transfection with miR-767 mimic promoted senescence of skin fibroblasts, while transfection with miR-767 inhibitor reversed the effect of D-galactose. Double luciferase analysis confirmed that TAB1 was a direct target gene of miR-767. Furthermore, miR-767 expression was increased and TAB1 expression was decreased in D-galactose induced aging mice. In mice that overexpressed miR-767, HE staining showed thinning of dermis and senescence appearance. In conclusion, senescent vascular endothelial cell-derived exosome mediated miR-767 regulates skin fibroblasts through the exosome pathway. Our study reveals the role of vascular endothelial cell-derived exosomes in aging in the skin microenvironment and contributes to the discovery of new targets for delaying senescence.

The interaction of MC3R and MC4R with MRAP2a in rainbow trout (Oncorhynchus mykiss) - Hui-Xia Yu; Yang Li; De-Bin Zhong; Xin Ren; Hao-Lin Mo; Ze-Bin Jiang; Jia-Jia Yu; Dong-Mei Xiong; Hai-Xia Liu; Li-Xin Wang (Fish Physiology and Biochemistry, 2023)

Soil organic carbon and nitrogen fractions as affected by straw and nitrogen management on the North China Plain - Guocui Ren; Xianfeng Zhang; Xiuli Xin; Wenliang Yang; Anning Zhu; Jiao Yang; Mengrou Li (Agriculture, Ecosystems & Environment, 2023)

Clinical evaluation of efficacy of leflunomide combined with low-dose prednisone for treatment of myasthenia gravis - Xin Huang; Li Qiu; Yaru Lu; Jiaxin Chen; Wenhao Yang; Changyi Ou; Hao Ran; Weibin Liu (Acta Neurologica Belgica, 2023)

De Novo Transcriptome Analysis of the Early Hybrid Triploid Loach (Misgurnus anguillicaudatus) Provides Novel Insights into Fertility Mechanism - Ziyu Zhou; Gu Shan; Xin Li; Wenxuan Guo; Kexin Ma; Yueyao Yang; Yifan Li; Yunbang Zhang; He Zhou; Xiaojuan Cao (Fishes, 2023)
As a new freshwater aquaculture product, triploid loaches (Misgurnus anguillicaudatus) are characterized by fast growth, high-quality meat, high edibility, high resistance to disease, and sterility. In this study, a natural tetraploid loach (4n = 100) (♀) was crossed with a diploid loach (2n = 50) (♂), thus creating the hybrid triploid loach (3n = 75). The histological observations of triploid offspring and diploid controls at 4 days post-hatching (dph), 15dph, 22dph, and 50dph showed that most of the hybrid triploid loaches were abortive in the early gonad differentiation process. To explore its fertility mechanism, through transcriptome analyses of triploid offspring and diploid controls at four periods, 10 differentially expressed genes related to the early fertility mechanism were identified: amh, hormad1, rec8, h2b, plvap, zp3, h2a, nrb0b1, ddx4, and esr2. According to the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of DEGs, two pathways were identified that are closely related to the early fertility mechanism at 50dph: the estrogen signaling pathway and steroid biosynthesis. The findings laid a foundation for further exploration of their molecular inhibition mechanism in hybrid triploid loaches.

Comparative transcriptomic analysis of early fruit development in eggplant (Solanum melongena L.) and functional characterization of SmOVATE5 - Suli Shi; Dalu Li; Shaohang Li; Yingying Wang; Xin Tang; Yang Liu; Haiyan Ge; Huoying Chen (Plant Cell Reports, 2023)

Marine sediment nitrogen isotopes and their implications for the nitrogen cycle in the sulfate-methane transition zone - Xin Yang; Yihao Zhang; Xiaoming Sun; Li Xu; TingTing Chen (Frontiers in Marine Science, 2023)
Introduction Recent work has proposed that the nitrogen isotopes in marine sediments can be impacted by anaerobic oxidation of methane (AOM), since nitrogen uptake by anaerobic methanotrophic archaea (ANME) modifies the nitrogen isotope compositions of bulk sediment. Thus, unraveling the AOM-driven nitrogen cycle in the sulfate-methane transition zone (SMTZ) becomes significant. Additional study of the nitrogen cycle between sediment and interstitial water in SMTZ is needed. Methods To better understand the nitrogen cycle in the SMTZ, we analyzed NH4+ concentrations of interstitial water and nitrogen isotopes of sediment in the core GC10 from the southwestern Taiwan Basin in the South China Sea. Results The defined SMTZ is located at 560–830 cmbsf, based on methane and sulfate concentrations, as well as TS/TOC ratios, δ13CTIC and δ34S values. In the SMTZ, the NH4+ concentration decreases, the δ15NTN shows a negative excursion, δ15Ndecarb displays a positive excursion. Discussions NH4+ concentration decrease is interpreted by sulfate-reducing ammonium oxidation (SRAO). The δ15NTN shows negative excursion, which is most likely interpreted to N2 (δ15N=0‰) released from SRAO that was fixed into marine sediment via ANME nitrogen fixation. The δ15Ndecarb shows a negative correlation with NH4+ concentrations, indicating that it was controlled by organic matter decomposition. In the SMTZ, the methane competes with organic matter for becoming the substrate of sulfate reduction bacteria, which possibly decreases the organic matter degradation rate and causes δ15Ndecarb relative positive excursion. Although δ15Ndecarb is controlled by organic matter degradation, δ15NTN still reveals a negative excursion in the SMTZ. This likely indicates that nitrogen uptake by ANME/AOM microbial consortiums mainly modifies the nitrogen isotope of soluble nitrogen in the SMTZ. Conclusions This study indicates unique geochemistry processes in SMTZ will modify nitrogen characteristics in sediment/interstitial water, and the latter can serve as a proxy for AOM.

Intermittent hypoxia exposure alleviates 2,4,6-trinitrobenzene sulfonic acid-induced enteritis by enhancing the intestinal barrier and inhibiting endoplasmic reticulum stress in juvenile largemouth bass - Dongmei Zhang; Liulan Zhao; Qishuang He; Ahmed Abdi Adam; Kuo He; Lisen Li; Xin Zhang; Jie Luo; Wei Luo; Zhiqiong Li; Song Yang; Qiao Liu (Aquaculture, 2023)

Gill histological and transcriptomic analysis provides insights into the response of spotted sea bass (Lateolabrax maculatus) to alkalinity stress - Yonghang Zhang; Haishen Wen; Yang Liu; Xin Qi; Donglei Sun; Chong Zhang; Kaiqiang Zhang; Meizhao Zhang; Jifang Li; Yun Li (Aquaculture, 2023)

Quantitative evaluation of variation and driving factors of the regional water footprint for cotton production in China - Qinqin Li; Weibin Huang; Jian Wang; Zhenggui Zhang; Yabing Li; Yingchun Han; Lu Feng; Xiaofei Li; Beifang Yang; Guoping Wang; Yaping Lei; Shiwu Xiong; et al. (Sustainable Production and Consumption, 2023)

Mapping Chinese annual gross primary productivity with eddy covariance measurements and machine learning - Xian-Jin Zhu; Gui-Rui Yu; Zhi Chen; Wei-Kang Zhang; Lang Han; Qiu-Feng Wang; Shi-Ping Chen; Shao-Min Liu; Hui-Min Wang; Jun-Hua Yan; Jun-Lei Tan; Fa-Wei Zhang; et al. (Science of The Total Environment, 2023)

Effects of environmental and anthropogenic factors on the distribution and abundance of microplastics in freshwater ecosystems - Weixiang Li; Xin Li; Jing Tong; Weiping Xiong; Ziqian Zhu; Xiang Gao; Shuai Li; Meiying Jia; Zhaohui Yang; Jie Liang (Science of The Total Environment, 2023)

Meeting China’s electricity demand with renewable energy over Tibetan Plateau - Wenjun Tang; Shan Xu; Xu Zhou; Kun Yang; Yang Wang; Jun Qin; Haikun Wang; Xin Li (Science Bulletin, 2023)

Typical layered structure bismuth-based photocatalysts for photocatalytic nitrogen oxides oxidation - Chi Ma; Jingjing Wei; Kainian Jiang; Jiaqi Chen; Zhongzhu Yang; Xu Yang; Guanlong Yu; Chang Zhang; Xin Li (Science of The Total Environment, 2023)

Transcription factor NtWRKY33a modulates the biosynthesis of polyphenols by targeting NtMYB4 and NtHCT genes in tobacco - Zhong Wang; Lanxin Ma; Pingping Liu; Zhaopeng Luo; Zefeng Li; Mingzhu Wu; Xin Xu; Wenxuan Pu; Pingjun Huang; Jun Yang (Plant Science, 2023)

Widely targeted metabolomics analysis reveals the effect of exogenous auxin on postharvest resistance to Botrytis cinerea in kiwifruit (Actinidia chinensis L.) - Zhe-Xin Li; Shuai Yang; Xu Wang; Qin-Hong Liao; Wen-Lin Zhang; Jing Liu; Guo-Hua Liu; Jian-Min Tang (Postharvest Biology and Technology, 2023)

Study on a tracked amphibious robot bionic fairing for drag reduction - Zefeng Yan; Mingda Li; Zihao Du; Xin Yang; Ying Luo; Xuedong Chen; Bin Han (Ocean Engineering, 2023)

Enhanced silicate remediation in cadmium-contaminated alkaline soil: Amorphous structure improves adsorption performance - Lulu Long; Na Huang; Xin Liu; Li Gong; Min Xu; Shirong Zhang; Chao Chen; Jun Wu; Gang Yang (Journal of Environmental Management, 2023)

Effect of gradual increase of atmospheric CO2 concentration on nitrification potential and communities of ammonia oxidizers in paddy fields - Bing-jie Ren; Li-dong Shen; Xin Liu; Jing-hao Jin; He-chen Huang; Mao-hui Tian; Yu-ling Yang; Wang-ting Yang; Jia-qi Liu; Cai-yu Geng; Hong-sheng Wu; Zheng-hua Hu (Journal of Environmental Management, 2023)

Atmospheric environment monitoring technology and equipment in China: A review and outlook - Youwen Sun; Ting Yang; Huaqiao Gui; Xin Li; Weigang Wang; Jun Duan; Shushuai Mao; Hao Yin; Bin Zhou; Jianlei Lang; Haijin Zhou; Cheng Liu; et al. (Journal of Environmental Sciences, 2023)

Impact of air pollutants on influenza-like illness outpatient visits under urbanization process in the sub-center of Beijing, China - Zhong-Song Zhang; Lu Xi; Li-Li Yang; Xin-Yao Lian; Juan Du; Yan Cui; Hong-Jun Li; Wan-Xue Zhang; Chao Wang; Bei Liu; Yan-Na Yang; Fuqiang Cui; et al. (International Journal of Hygiene and Environmental Health, 2023)

Multi-objective optimization of the performance and emission characteristics for a dual-fuel engine with hydrogen addition - Zhonghang Liu; Jianbin Luo; Yajuan Pan; Jian Li; Longjie Li; Xin Wei; Hongxiang Xu; Yuanhao Tie; Chengtao Zhang; Dayong Yang (Fuel, 2023)

Analysis of flavonoid-related metabolites in different tissues and fruit developmental stages of blackberry based on metabolome analysis - Yaqiong Wu; Xin Huang; Hao Yang; Shanshan Zhang; Lianfei Lyu; Weilin Li; Wenlong Wu (Food Research International, 2023)

Rapid identification of fish species by laser-induced breakdown spectroscopy and Raman spectroscopy coupled with machine learning methods - Lihui Ren; Ye Tian; Xiaoying Yang; Qi Wang; Leshan Wang; Xin Geng; Kaiqiang Wang; Zengfeng Du; Ying Li; Hong Lin (Food Chemistry, 2023)

Associations between greenspace surrounding schools and lipid levels in Chinese children and teenagers - Li-Xin Hu; Shujun Fan; Yinghua Ma; Xiao-Xuan Liu; Wen-Wen Bao; Yuming Guo; Li-Wen Hu; Gongbo Chen; Xiao-Wen Zeng; Zhiyong Zou; Bo-Yi Yang; Jun Ma; et al. (Environmental Pollution, 2023)

Association between ambient carbon monoxide levels and hospitalization costs of patients with myocardial infarction: Potential effect modification by ABO blood group - Qing-Song Huang; Lai-Xin Zhou; Li-Li Yang; Yue-Xu Jiang; Hua Xiao; Da-Wei Li; Yu-Meng Zhou; Yue-Gu Hu; Na Li; Ya-Fei Li; Ai-Ling Ji; Peng Luo; et al. (Environmental Research, 2023)

Air pollution, greenness and risk of overweight among middle-aged and older adults: A cohort study in China - Wenxing Han; Zhihu Xu; Xin Hu; Ru Cao; Yuxin Wang; Jianbo Jin; Jiawei Wang; Teng Yang; Qiang Zeng; Jing Huang; Guoxing Li (Environmental Research, 2023)

Enhanced phonon scattering and thermoelectric performance for N-type Bi2Te2.7Se0.3 through incorporation of conductive polyaniline particles - Shuhuan Yang; Hongwei Ming; Di Li; Tao Chen; Shujin Li; Jian Zhang; Hongxing Xin; Xiaoying Qin (Chemical Engineering Journal, 2023)

Expanding the gallery of solvent-free nanofluids: Using layered double hydroxides as core nanostructures - Xiaoqian Ju; Zhiyuan Yang; Dechao Wang; Xinbo Duan; Yangyang Xin; Hanbo Zhu; Xiaoqian Li; Yinyan Li; Dongdong Yao; Yaping Zheng (Chemical Engineering Journal, 2023)

Enhanced proton pseudocapacitive of Ti3C2Tx in neutral electrolyte activated by acid regulation dynamic pillars - Rang Ping; Yulin Nie; Chongkai Ji; Zhigang Hao; Shun Yang; Lijie Li; Jiong Peng; Xin Li (Chemical Engineering Journal, 2023)

High-strength, self-initiated, wide pH range of underwater adhesive suitable for different severe environments - Junyu Ren; Guanben Du; Sichen Liu; Hongxing Yang; Xin Ran; Chang Liu; Tongda Liu; Zhi Li; Xiaojian Zhou; Wei Gao; Bei Zhou; Long Yang (Chemical Engineering Journal, 2023)

Label-free therapeutic drug monitoring in human serum by the 3-step surface enhanced Raman spectroscopy and multivariate analysis - Yunpeng Wang; Cuiwei Yu; Haoyu Ji; Zhehan Liu; Xiaotong Wang; Yinghe Ji; Xiaomeng Sun; Yue Zhao; Xiaohong Qiu; Ting Zhang; Jing Li; Xin Liu; et al. (Chemical Engineering Journal, 2023)

Fe3+ and chlorotrimethylsilane modified NaY catalysts display enhanced activity and durability for acetalization of glycerol to solketal - Yushan Li; Qingqing Xie; Mengyu Wang; Zhenyang Wang; Jiefeng Liu; Yiyao Du; Dongpei Zhang; Mengyuan Liu; Guangyu Zhang; Xin Jin; Chaohe Yang (Chemical Engineering Journal, 2023)

N-Rich carbon as Zn2+ modulation layers for dendrite-free, highly reversible zinc anodes - Xin Wang; Konghua Yang; Chenhui Ma; Wenqiang Lu; Nan Chen; Mingguang Yao; Zhenjiang Li; Chunbao Liu; Huijuan Yue; Dong Zhang; Fei Du (Chemical Engineering Journal, 2023)

Boosting doxil-based chemoimmunotherapy via reprogramming tumor-associated macrophages - Xiaoqiong Zhang; Zhaohan Wei; Ziqiao Ding; Weilin Lv; Jianye Li; Xin Li; Haojie Liu; Panli Yu; Xiangliang Yang; Lu Gan (Chemical Engineering Journal, 2023)

A robust ROS generation nanoplatform combating periodontitis via sonodynamic/chemodynamic combination therapy - Yujia Xin; Zhaoyang Guo; Aijing Ma; Enyu Shi; Zhiyuan Li; Zonghao Liang; Zhanyin Qian; Lan Yang; Yinsong Wang; Mingxin Cao; Xiaoying Yang (Chemical Engineering Journal, 2023)

Easy regulation of chitosan-based hydrogel microstructure with citric acid as an efficient buffer - Keyi Li; Xueting Yang; Xin Dong; Hongyan Cao; Shujuan Zhuang; Xiangling Gu (Carbohydrate Polymers, 2023)

Ir nanodots decorated Ni3Fe nanoparticles for boosting electrocatalytic water splitting - Yaru Li; Yong-Chen Miao; Chen Yang; Yu-Xin Chang; Yu Su; Hong Yan; Sailong Xu (Chemical Engineering Journal, 2023)

Effects of mold, water damage and window pane condensation on adult rhinitis and asthma partly mediated by different odors - Juan Wang; Yinping Zhang; Baizhan Li; Zhuohui Zhao; Chen Huang; Xin Zhang; Qihong Deng; Chan Lu; Hua Qian; Xu Yang; Yuexia Sun; Dan Norbäck (Building and Environment, 2023)

New species of Leccinum from Southwest China - Pan Meng Wang; Xin Meng; Zhu L. Yang; Yan Chun Li (Mycological Progress, 2023)

Climate and soil properties drive soil organic and inorganic carbon patterns across a latitudinal gradient in southwestern China - Xiaojuan Li; Tinghui Yang; Lettice C. Hicks; Bin Hu; Fanglan Li; Xin Liu; Dandan Wei; Zilong Wang; Weikai Bao (Journal of Soils and Sediments, 2023)

Development, characterisation, and in vitro anti-tumor effect of self-microemulsifying drug delivery system containing polyphyllin I - Xin Wang; Rui Zhang; Shu Wang; Minju Gu; Yuan Li; Xiuping Zhuang; Chao Chen; Peimin Yang; Gongling Guo; Ping Sun (Drug Delivery and Translational Research, 2023)

Precise orbit determination for BDS-3 GEO satellites enhanced by intersatellite links - Xiaojie Li; Xiaogong Hu; Rui Guo; Chengpan Tang; Shuai Liu; Jie Xin; Jinglei Guo; Yijun Tian; Yufei Yang; Jianhua Yang; Xinglong Zhao (GPS Solutions, 2023)

Solar ring mission: Building a panorama of the Sun and inner-heliosphere - Yuming Wang; Xianyong Bai; Changyong Chen; Linjie Chen; Xin Cheng; Lei Deng; Linhua Deng; Yuanyong Deng; Li Feng; Tingyu Gou; Jingnan Guo; Yang Guo; et al. (Advances in Space Research, 2023)

Epigenetic‐associated phenotypic plasticity of the ocean acidification‐acclimated edible oyster in the mariculture environment - Xin Dang; Yong‐Kian Lim; Yang Li; Steven B. Roberts; Li Li; Vengatesen Thiyagarajan (Molecular Ecology, 2023)
For marine invertebrates with a pelagic–benthic life cycle, larval exposure to ocean acidification (OA) can affect adult performance in response to another environmental stressor. This carry‐over effect has the potential to alter phenotypic traits. However, the molecular mechanisms that mediate “OA”‐triggered carry‐over effects have not been explored despite such information being key to improving species fitness and management strategies for aquafarming. This study integrated the genome‐wide DNA methylome and transcriptome to examine epigenetic modification‐mediated carry‐over OA impacts on phenotypic traits of the ecologically and commercially important oyster species Crassostrea hongkongensis under field conditions. Larvae of C. hongkongensis were exposed to control pH 8.0 and low pH 7.4 conditions, mimicking near future OA scenario in their habitat, before being outplanted as post‐metamorphic juveniles at two mariculture field sites with contrasting environmental stressors for 9 months. The larval carry‐over OA effect was found to have persistent impacts on the growth and survival trade‐off traits on the outplanted juveniles, although the beneficial or adverse effect depended on the environmental conditions at the outplanted sites. Site‐specific plasticity was demonstrated with a diverse DNA methylation‐associated gene expression profile, with signal transduction and the endocrine system being the most common and highly enriched functions. Highly methylated exons prevailed in the key genes related to general metabolic and endocytic responses and these genes are evolutionarily conserved in various marine invertebrates in response to OA. These results suggest that oysters with prior larval exposure history to OA had the ability to trigger rapid local adaptive responses via epigenetic modification to cope with multiple stressors in the field.

Simulation and projection of climate extremes in China by multiple Coupled Model Intercomparison Project Phase 6 models - Linxiao Wei; Xiaoge Xin; Qilin Li; Yao Wu; Hongyu Tang; Yonghua Li; Baogang Yang (International Journal of Climatology, 2023)
This study evaluates the ability of 23 climate models from phase 6 of the Coupled Model Intercomparison Project (CMIP6) in simulating extreme climate events over China. The multimodel ensemble (MME) performs better than most individual models in reproducing the climatological mean distribution of all extreme indices. The MME can reproduce well the climatological mean distributions of five extreme climate indices over China, including annual total precipitation (PTOT), maximum consecutive 5‐day precipitation (RX5), simple daily intensity (SDII), maximum daily maximum temperature (TXX), and minimum daily minimum temperature (TNN), with Taylor skill scores exceeding 0.7. SDII and TXX are the most skilful precipitation and temperature extreme indices simulated by the MME, respectively. The MME has relatively lower skill in simulating the climatological mean distribution of warm days (TX90P) and cold nights (TN10P) over China. Future projections of these extreme climate indices by the end of the 21st century are explored with the MME under the SSP1‐2.6, SSP2‐4.5, and SSP5‐8.5 scenarios. The PTOT and RX5 in northwestern China are all projected to increase by more than 30% under SSP5‐8.5. R20 is projected to increase by 4–5 days over southeastern China under SSP5‐8.5. There are fewer (more) consecutive dry days over north China (south China), with a change of 5 days under SSP5‐8.5. The extreme temperature indices, including TX90P, TXX, and TNN, all increase with time and higher SSP scenarios. The three indices increase by 40–55%, 4–6°C, and 4–7°C under SSP5‐8.5 over east China, respectively. The TN10P decreases by more than 6% over east China. The changes in these extreme indices under SSP1‐2.6 and SSP2‐4.5 are similar to those under SSP5‐8.5 but with a smaller magnitude. Large uncertainties still exist in the future projections, especially under the high SSP scenarios.

Warming reduced flowering synchrony and extended community flowering season in an alpine meadow on the Tibetan Plateau - Yaya Chen; Scott L. Collins; Yunpeng Zhao; Tianwu Zhang; Xiangrong Yang; Hang An; Guorui Hu; Chunming Xin; Juan Zhou; Xiongjie Sheng; Mingrui He; Panhong Zhang; et al. (Ecology, 2023)
The timing of phenological events is highly sensitive to climate change, and may influence ecosystem structure and function. Although changes in flowering phenology among species under climate change have been reported widely, how species‐specific shifts will affect phenological synchrony and community‐level phenology patterns remains unclear. We conducted a manipulative experiment of warming and precipitation addition and reduction to explore how climate change affected flowering phenology at the species and community levels in an alpine meadow on the eastern Tibetan Plateau. We found that warming advanced the first and last flowering times differently and with no consistent shifts in flowering duration among species, resulting in the entire flowering period of species emerging earlier in the growing season. Early‐flowering species were more sensitive to warming than mid‐ and late‐flowering species, thereby reducing flowering synchrony among species and extending the community‐level flowering season. However, precipitation and its interactions with warming had no significant effects on flowering phenology. Our results suggest that temperature regulates flowering phenology from the species to community levels in this alpine meadow community, yet how species shifted their flowering timing and duration in response to warming varied. This species‐level divergence may reshape flowering phenology in this alpine plant community. Decreasing flowering synchrony among species and the extension of community‐level flowering seasons under warming may alter future trophic interactions, with cascading consequences to community and ecosystem function.

Permian mountain building in the bogda mountains of NW China - Yalong Li; Xin Shan; Katrina D. Gelwick; Xinghe Yu; Lina Jin; Zongquan Yao; Shunli Li; Shouye Yang (International Geology Review, 2022)

Establishment and comprehensive analysis of a new human cell line (NK-NJ) with NK-cell characteristics established from extranodal natural killer cell lymphoma/leukemia - Jin-Hua Liang; Wei-Ting Wang; Kai-Xin Du; Tong-Yao Xing; Yan Wang; Hui Wang; Lu Liu; Rui Guo; Yang Shao; Junheng Liang; Yue Li; Hao-Rui Shen; et al. (Human Cell, 2022)

Comprehensive genetic analysis reveals seed germination activity-related QTL and meta-QTL in rice (Oryza sativa L.) - Pen Li; Hualong Liu; Haoran Wen; Luomiao Yang; Ziqi Chen; Hongliang Zheng; Wei Xin; Dezhuang Zhang; Jingguo Wang; Detang Zou (Genetic Resources and Crop Evolution, 2022)

Detecting geothermal anomalies using Landsat 8 thermal infrared remote sensing data in the Ruili Basin, Southwest China - Jiangqin Chao; Zhifang Zhao; Zhibin Lai; Shiguang Xu; Jianyu Liu; Ziyang Li; Xinle Zhang; Qi Chen; Haiying Yang; Xin Zhao (Environmental Science and Pollution Research, 2022)

Abietane diterpenoids with neuroprotective activities from Phlegmariurus carinatus - Yang Liu; Qiang Wang; Dong-Kun Zheng; De Zhang; Zhen Xie; Jia-Wei Hu; Xin-Hua Xie; Jing Li; Shu-Ping Jiang (Natural Product Research, 2022)

Transcriptomes of Different Tissues for Expression Characteristics Analysis of MYB gene Family in Kenaf (Hibiscus cannabinus L.) - Hu Li; Xin Yang; Sylvain Niyitanga; Qinyao He; Siyuan Chen; Jiantang Xu; Jianmin Qi; Aifen Tao; Pingping Fang; Liwu Zhang (Tropical Plant Biology, 2022)

Pinb-D1p is an elite allele for improving end-use quality in wheat (Triticum aestivum L.) - Siyuan Chang; Qian Chen; Tao Yang; Binyong Li; Mingming Xin; Zhenqi Su; Jinkun Du; Weilong Guo; Zhaorong Hu; Jie Liu; Huiru Peng; Zhongfu Ni; et al. (Theoretical and Applied Genetics, 2022)
Key message We identified ten QTLs controlling SDS-SV trait in a RIL population derived from ND3331 and Zang1817. Pinb-D1p is an elite allele from Tibetan semi‑wild wheat for good end-use quality. Abstract Gluten strength is an important factor for wheat processing and end-product quality and is commonly characterized using the sodium dodecyl sulfate-sedimentation volume (SDS-SV) test. The objective of this study was to identify quantitative trait loci (QTLs) associated with wheat SDS-SV traits using a recombinant inbred line (RIL) population derived from common wheat line NongDa3331 (ND3331) and Tibetan semi-wild wheat accession Zang1817. We detected 10 QTLs controlling SDS-SV on chromosomes 1A, 1B, 3A, 4A, 4B, 5A, 5D, 6B and 7A, with individual QTLs explaining 2.02% to 15.53% of the phenotypic variation. They included four major QTLs, Qsdss-1A , Qsdss-1B.1 , Qsdss-1B.2 , and Qsdss-5D , whose effects on SDS-SV were due to the Glu-A1 locus encoding the high-molecular-weight glutenin subunit 1Ax1, the 1B/1R translocation, 1Bx7 + 1By8 at the Glu-B1 locus, and the hardness-controlling loci Pina-D1 and Pinb-D1 , respectively. We developed KASP markers for the Glu-A1 , Glu-B1 , and Pinb-D1 loci. Importantly, we showed for the first time that the hardness allele Pinb-D1p positively affects SDS-SV, making it a good candidate for wheat quality improvement. These results broaden our understanding of the genetic characterization of SDS-SV, and the QTLs identified are potential target regions for fine-mapping and marker-assisted selection in wheat breeding programs.

Research on time series InSAR monitoring method for multiple types of surface deformation in mining area - Ya-xing Li; Ke-ming Yang; Jian-hong Zhang; Zhi-xian Hou; Shuang Wang; Xin-ming Ding (Natural Hazards, 2022)

FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS - Binbin Zhou; Yilei Zheng; Xiaobing Li; Huifang Dong; Jiaxi Yu; Yang Zou; Min Zhu; Yanyan Yu; Xin Fang; Meihong Zhou; Wei Zhang; Yun Yuan; et al. (Molecular Neurobiology, 2022)

Enhance energy supply of largemouth bass (Micropterus salmoides) in gills during acute hypoxia exposure - Qiao Liu; Hong Wang; Jiayu Ge; Jie Luo; Kuo He; Haoxiao Yan; Xin Zhang; Rabia Tahir; Wei Luo; Zhiqiong Li; Song Yang; Liulan Zhao (Fish Physiology and Biochemistry, 2022)

Laboratory study of Se speciation in the sediment and oligochaete Lumbriculus variegatus from an aquatic environment - Jichen Yang; Xin Yan; Hongsong Liu; Hongxing Chen; Wei Zhang; Wu Dong; Dan Li; Lingtian Xie (Environmental Science and Pollution Research, 2022)

A modified TOPMODEL introducing the bedrock surface topographic index in Huangbengliu watershed, China - An-ni Qiu; Yan-jun Zhang; Gen-xu Wang; Jun Cui; Yuan-xin Song; Xiang-yang Sun; Li Chen (Journal of Mountain Science, 2022)

Carbonate microfacies classification model based on dual neural network: a case study on the fourth member of the upper Ediacaran Dengying Formation in the Moxi gas field, Central Sichuan Basin - Keran Li; Jinmin Song; Haijun Yan; Shugen Liu; Di Yang; Zhiwu Li; Xin Jin; Jiaxin Ren; Lingli Zhao; Jiarui Wang (Arabian Journal of Geosciences, 2022)
The dual neural network (DNNW) model combines two neural networks to imitate artificial sedimentary facies division by learning the characteristics of multi-type logging curves corresponding to the sedimentary microfacies of a coring section. The model predicts many non-coring wells in the research zone through logging data. After comparing the classification performance of a fully connected neural network (FCNWW) and AutoML when dealing with three FNDA, EALS, and HRA datasets, the DNNW shows high stability and assists exploration in the Moxi gas field. Four sedimentary microfacies are identified through thin section observation, including thrombolite boundstone (MF1), laminated stromatolite boundstone (MF2), siliceous laminar boundstone (MF3), and micritic dolostone (MF4). Results suggest the fourth member of Dengying Formation in the Moxi gas field is carbonate platform facies deposition: specifically, restricted platform and platform margin.

Temporal and spatial changes in land use and ecosystem service value based on SDGs’ reports: a case study of Dianchi Lake Basin, China - Zhuoya Zhang; Jiaxi Li; Yu Lu; Li Yang; Zheneng Hu; Changyuan Li; Xin Yang (Environmental Science and Pollution Research, 2022)

Atmospheric simulation‐based precipitation datasets outperform satellite‐based products in closing basin‐wide water budget in the eastern Tibetan Plateau - Yaozhi Jiang; Kun Yang; Xiaodong Li; Wenjiang Zhang; Yan Shen; Yingying Chen; Xin Li (International Journal of Climatology, 2022)
Satellite‐based precipitation products (SBPs) have been widely used in hydrological applications in recent decades but may contain large uncertainties in mountainous regions. Atmospheric simulation‐based datasets (ABDs) have been greatly improved in recent years, but their applications in mountainous hydrology are rare and need further validation. This study compares the performance of three SBPs and two ABDs in the mountainous Minjiang River basin, focusing on their potential for closing the basin‐wide water budget. The three SBPs include the China Merged Precipitation Analysis (CMPA), the Integrated Multi‐satellitE Retrievals for Global Precipitation Measurement (IMERG) and the Global Satellite Mapping of Precipitation (GSMaP); the two ABDs are the fifth generation Reanalysis product of the European Centre for Medium Range Weather Forecasts (ERA5) and the High Asia Refined Analysis Version 2 (HAR V2). The five products are validated with rain gauge data and results show that all the five products except IMERG can generally reproduce the spatial pattern and elevation dependence of observed precipitation. Particularly, precipitation amount in the two ABDs is close to gauge observations in the low elevations, but much more than the gauge observations in areas with a sharp rise in elevations. Assessment of water budget shows that all SBPs yield severe negative water imbalance (greater than 50.0% of corresponding runoff) at most sub‐basins, while the ABDs can better close the water budget with water imbalance values between ±30.0% in most sub‐basins, respectively. Further analyses show that large relative differences between SBPs and ABDs mainly occur in areas with large topographical relief and in winter, which is likely because the ABDs outperform the SBPs in capturing orographic precipitation in complex terrain and solid precipitation in winter.

The nutrient removal and tolerance mechanism of a heterotrophic nitrifying bacterium Pseudomonas putida strain NP5 under metal oxide nanoparticles stress - Huan-Huan Liu; Lei Yang; Lin-Kai Guo; Li-Xin Tu; Xiao-Tong Li; Jia Wang; Yong-Xiang Ren (Environmental Science and Pollution Research, 2022)

In-situ photoreduction strategy for synthesis of silver nanoparticle-loaded PVDF ultrafiltration membrane with high antibacterial performance and stability - Shanshan Dong; Helin Hua; Xin Wu; Xuhui Mao; Na Li; Xinping Zhang; Kun Wang; Shengyun Yang (Environmental Science and Pollution Research, 2022)

Spatiotemporal coastline variations in the Pearl River Estuary and the relationship with multiple human disturbances - Xin Li; Haiming Yan; Ying Yang; Zhihao Xu; Huicai Yang (Frontiers in Marine Science, 2022)
Coastlines and estuaries as one of the most dynamic systems in the marine environment are influenced by not only natural factors but also various anthropogenic activities, but there have been limited comprehensive studies on the relationship between coastline variation and anthropogenic activities at the watershed and local scales. The Pearl River Estuary (PRE) in China has experienced remarkable coastline variation along with rapid economic development and urbanization. In this study, the coastline of the PRE was extracted using Landsat images during 1987-2017, and the impacts of multiple factors on coastline variation were explored with correlation analysis and regression analysis. Results suggested coastlines of the PRE demonstrated a clear expanding trend over recent decades, and the coastline length had increased by 74.81 km and the land area had increased by 679.25 km 2 by 2017, and results also showed rapid coastline variation during 1987-2004 and relatively slow variation during 2004-2017. Artificial coastlines accounted for 80.90% of the total coastline length in 2017, while natural coastlines accounted for only 19.10%. In addition, reduction in the sand content caused by construction of reservoirs and river dredging in upstream areas played a dominant role in affecting natural coastline variation in the PRE, especially on the west coast. Moreover, the artificial coastline in the study area expanded quickly due to the influence of various human activities, among which the urbanization and land reclamation for aquaculture played a dominant role in affecting the artificial coastline variation on the east and west coasts, respectively. Results of this study have important value for understanding the individual and joint effects of various human activities on coastline variation and can provide important reference information for the sustainable management of the PRE as well as other estuaries.

The Influence of the Rotary Speed of a Microwave Applicator on Hard-Rock Fracturing Effect - Xia-ting Feng; Shi-ping Li; Cheng-xiang Yang; Feng Lin; Tian-yang Tong; Xiang-xin Su; Jiu-yu Zhang (Rock Mechanics and Rock Engineering, 2022)

Comparative genomic investigation of TCP gene family in eggplant (Solanum melongena L.) and expression analysis under divergent treatments - Dalu Li; Xin Tang; Yanxiao Dong; Yingying Wang; Suli Shi; Shaohang Li; Yang Liu; Haiyan Ge; Huoying Chen (Plant Cell Reports, 2022)

High levels of serum IL-10 indicate disease progression, extramedullary involvement, and poor prognosis in multiple myeloma - Xiaoyan Yue; Linlin Huang; Yang Yang; Yi Zhao; Donghua He; Xiaoyan Han; Gaofeng Zheng; Yi Li; Enfan Zhang; Zhen Cai; Xin Huang; Jingsong He (Journal of Zhejiang University-SCIENCE B, 2022)

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice - Bo Yang; Zhan Gao; Qi-Shuang Li; Xiang-Ye Zhang; Lan Song; Yi-Ni Wang; Xin-Yue Wang; Lin-Lin Ji; Hong-Liang Xu; Hui Xie; Fu-Kai Feng; Xiao-Ping Li; et al. (Inflammation Research, 2022)

Seasonal variations alter the effect of an invasive plant on the decomposition of a native plant in a subtropical eutrophic lake, China - Shaojun Chen; Shanze Li; Ling Liu; Yuchun Wang; Xin Zeng; Siyu Long; Huanyu Zhou; Jinghao Yang; Fengyu Li; Huapei Luo (Hydrobiologia, 2022)

Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans - Huan Wu; Xin Zhang; Rong Hua; Yuqian Li; Li Cheng; Kuokuo Li; Yiyuan Liu; Yang Gao; Qunshan Shen; Guanxiong Wang; Mingrong Lv; Yuping Xu; et al. (Human Genetics, 2022)

The ubiquitin ligase RNF2 stabilizes ERα and modulates breast cancer progression - Lei Yuan; Xin Li; Huijie Yang; Huixiang Li (Human Cell, 2022)
Estrogen receptor α (ERα) is the most common clinical marker used for breast cancer prognosis and the classification of breast cancer subtypes. Clinically, patients with estrogen receptor-positive breast cancer can receive endocrine therapy. However, resistance to endocrine therapy has become an urgent clinical problem. A large number of previous studies have proven that posttranslational modification of the estrogen receptor is significantly related to endocrine therapy resistance. RNF2 is a member of the RING finger protein family that functions as an E3 ubiquitin ligase. Several studies have clarified that RNF2 is a critical regulator of ERα transcriptional regulation. In our current study, we identified RNF2 as an important posttranslational modification regulator of the estrogen receptor. RNF2 depletion inhibited breast cancer cell progression and ERα signaling activity. TCGA data analysis indicated that RNF2 was elevated in breast malignancies, while RNF2 depletion could drastically inhibit estrogen response gene expression on a whole-genome scale. TCGA data analysis revealed that RNF2 was positively correlated with ERα target gene expression. Further mechanistic studies showed that RNF2 was mainly localized in the nucleus and associated with ERα. The association increased ERα stability by inhibiting ERα K48-linked polyubiquitination. In conclusion, our study implicates nongenomic regulation by RNF2 on ERα protein stability and suggests that targeting RNF2 could be a promising strategy for breast cancer treatments.

Study on Fatigue Spectrum Analysis and Reliability Analysis of Multilayer Flexible Riser - Jianxing Yu; Fucheng Wang; Yang Yu; Haoda Li; Xin Liu; Ruoke Sun (Journal of Marine Science and Engineering, 2022)
Multilayer composite flexible risers have been widely used in engineering. However, this type of structure is complex, as there are influences between layers. Moreover, a range of uncertain factors need to be considered in fatigue analysis. Therefore, it is difficult to perform the fatigue analysis research of multilayer flexible risers. In this paper, the fatigue spectrum analysis and reliability analysis method of a nine-layer flexible riser structure are proposed, and a complete fatigue and reliability analysis process for multilayer structures is developed. The theoretical basis of the fatigue spectrum analysis method is introduced, and the calculation program is described. Finite element software is used to analyze the stress of the multilayer flexible riser under the influence of the upper platform structure movement and the ocean current. Moreover, the stress response of the riser structure of each layer is obtained. According to this, the irregular wave load is simulated by the method of random number simulation, and the stress response spectrum is formed. Then, the appropriate S-N curve is selected to calculate the fatigue damage degree of each layer, and the fatigue damage nephogram is displayed, so as to analyze the structural fatigue damage. Finally, the uncertainty in the process of fatigue damage calculation is analyzed. According to the results, the methods of multilayer riser analysis are summarized and the future research directions are put forward.

MiRNA let-7i promotes radiation-induced pulmonary epithelial-mesenchymal transition by targeting IL-10 - Shenghui Zhou; Xin Liang; Zewen Sun; Xueping Li; Jiaojiao Zhu; Zhihua Yang; Xiujie Pan; Yilong Wang; Yongqing Gu; Maoxiang Zhu (Genome Instability & Disease, 2022)

Two new alkaloids from Tibetan medicine of Hypecoum leptocarpum - Bo Sun; Israa Assani; Chun-Gu Wang; Mu-Xuan Wang; Ling-Fei Liu; Yan Li; Ge Yan; Yun-Ruo Yang; Zhi Chen; Zhi-Xin Liao (Natural Product Research, 2022)

The association between short-term ambient sulfur dioxide exposure and hospitalization costs of ischemic stroke: a hospital-based study in Chongqing, China - En-Jie Tang; Yu-Meng Zhou; Li-Li Yang; Nan Wang; Yue-Xu Jiang; Hua Xiao; Yue-Gu Hu; Da-Wei Li; Na Li; Qing-Song Huang; Ning Du; Ya-Fei Li; et al. (Environmental Science and Pollution Research, 2022)

Amino acid transporter gene TaATLa1 from Triticum aestivum L. improves growth under nitrogen sufficiency and is down regulated under nitrogen deficiency - Heng Chen; Yingchun Liu; Jiazhen Zhang; Yifei Chen; Cuican Dai; Renmei Tian; Tianxiang Liu; Mingxun Chen; Guang Yang; Zhonghua Wang; Hongxia Li; Xinyou Cao; et al. (Planta, 2022)

Pulsed Electromagnetic Field Protects Against Brain Injury After Intracerebral Hemorrhage: Involvement of Anti-Inflammatory Processes and Hematoma Clearance via CD36 - Yuefan Yang; Pan Wang; Anlai Liu; Xiuquan Wu; Zedong Yan; Shuhui Dai; Jialiang Wei; Zhuoyuan Zhang; Xin Li; Peng Luo; Erping Luo (Journal of Molecular Neuroscience, 2022)

Identification of resistance of Guangxi (Oryza rufipogon Griff.) to white-backed planthopper with stem evaluation method - Xin-ying Guo; Xuan Wang; Liang Luo; Yao-yu Fang; Kai-chong Teng; Neng Zhao; Jin-lian Yang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Genetic Resources and Crop Evolution, 2022)

Risk of thyroid cancer and benign nodules associated with exposure to parabens among Chinese adults in Wuhan, China - Nan-Xin Wu; Lang-Jing Deng; Feng Xiong; Jin-Ying Xie; Xiao-Jie Li; Qiang Zeng; Jia-Chen Sun; Da Chen; Pan Yang (Environmental Science and Pollution Research, 2022)

An update on microneedle-based systems for diabetes - Wen Xuan Li; Xiao Peng Zhang; Bo Zhi Chen; Wen Min Fei; Yong Cui; Can Yang Zhang; Xin Dong Guo (Drug Delivery and Translational Research, 2022)

Bioaccessibility and Toxicity Assessment of Polycyclic Aromatic Hydrocarbons in Two Contaminated Sites - Huihui Cao; Xiaona Li; Changsheng Qu; Meng Gao; Hu Cheng; Ni Ni; Shi Yao; Yongrong Bian; Chenggang Gu; Xin Jiang; Yang Song (Bulletin of Environmental Contamination and Toxicology, 2022)

Proteome and physiological analyses reveal tobacco (Nicotiana tabacum) peroxidase 7 (POD 7) functions in responses to copper stress - Qian Gao; Li Xu; Xiang Li; Wenwu Yang; Qili Mi; Liming Lu; Xin Liu; Kai Wang; Yifei Lu; Zhangyu Chen; Xuemei Li; Liqin Li (Transgenic Research, 2022)
Copper is a micronutrient essential for plant growth and development. However, Cu is also a heavy metal element that has deleterious impacts on plants when excessively accumulated in the environment. To understand the molecular mechanism underlying tobacco in response to Cu stress, iTRAQ based technology was used to identify differentially expressed proteins (DEPs) and important metabolic pathways in tobacco plants treated with excessive CuSO4. The results showed that 180 DEPs were detected between the treatment and control, among which 78 were upregulated and 102 were downregulated. These DEPs can be functionally divided into 65 categories and are closely related to metabolic pathways, carbon metabolism, secondary metabolite biosynthesis, biosynthesis of antibiotics, glyoxylate and dicarboxylate metabolism, and glycolysis/gluconeogenesis. Peroxidase7 was significantly upregulated and was selected and overexpressed in tobacco. Then, positive transgenic lines and wild type plants were exposed to a Cu stress environment. The results showed that Peroxidase7 transgenic tobacco plants exhibited enhanced Cu stress resistance with decreased malondialdehyde and Cu contents, and increased shoot dry weight, root length, secondary root number, SOD, POD and CAT activity. The present study suggests that the ROS scavenging mechanism is essential for tobacco plants in response to Cu stress and that Peroxidase7 functions in tobacco plant resistance to excessive Cu environment.

Overexpression of a Phosphatidylinositol-Specific Phospholipase C Gene from Populus simonii × P. nigra Improves Salt Tolerance in Transgenic Tobacco - Yao Sun; Yao Li; Xin Sun; Qiong Wu; Chunhui Yang; Lei Wang (Journal of Plant Biology, 2022)

Identification of terrigenous and autochthonous organic carbon in sediment cores from cascade reservoirs in the upper stream of Pearl River and Wujiang River, southwest China: lignin phenol as a tracer - Li Gao; Xin Lin; Jun Fan; Ming Yang; Xueping Chen; Fushun Wang; Jing Ma (Acta Geochimica, 2022)

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Studying bona fide SARS-CoV-2 biology in a BSL-2 biosafety environment using a split-virus-genome system - Yingxin Ma; Guobin Mao; Weishan Yang; Guoqiang Wu; Guoqiang Li; Xiaoying Li; Xin Lin; Junnan Lu; Shijun Zhao; Wei Zhao; Junbiao Dai; Xian-En Zhang (Science China Life Sciences, 2022)

Stat5−/− CD4+ T cells elicit anti-melanoma effect by CD4+ T cell remolding and Notch1 activation - Ke Jin; Tong Li; Zhiyong Miao; Jingjing Ran; Luyu Chen; Dachao Mou; Chuang Wang; Shasha Wu; Hanshuo Yang; Xin-Yuan Fu (Science China Life Sciences, 2022)

Identification of Genetic Loci and Candidate Genes Related to the Sensory and Textural Properties of Chinese White Noodles by Genome-wide Association Study Using Common Wheat (Triticum aestivum L.) - Wenshu Li; Guanying Wang; Wenqi Fang; Xin Guo; Yanli Liu; Xiaojie Yang; Guangfeng Chen; Jichun Tian; Hanfeng Ding; Yanxun Wang; Zhiying Deng (Plant Molecular Biology Reporter, 2022)

Pathological Networks Involving Dysmorphic Neurons in Type II Focal Cortical Dysplasia - Yijie Shao; Qianqian Ge; Jiachao Yang; Mi Wang; Yu Zhou; Jin-Xin Guo; Mengyue Zhu; Jiachen Shi; Yiqi Hu; Li Shen; Zhong Chen; Xiao-Ming Li; et al. (Neuroscience Bulletin, 2022)

Catalytic effect of cesium on the oxidation behavior of cation exchange resins in Li2CO3-Na2CO3-K2CO3 melt - Yang-Hai Zheng; Yong-De Yan; Yun Xue; Yue-Lin Wang; Xin Liu; Wan-Sheng Mi; Qing-Guo Zhang; Yu Li; Fu-Qiu Ma; Mi-Lin Zhang; Zhi-Hao Gan; Kai Zhu (Environmental Science and Pollution Research, 2022)

Evaluation of seawater intrusion and water quality prediction in Dagu River of North China based on fuzzy analytic hierarchy process exponential smoothing method - Haitao Yang; Chao Jia; Xin Li; Fan Yang; Cong Wang; Xiao Yang (Environmental Science and Pollution Research, 2022)

The effect of the nucleotides immediately upstream of the AUG start codon on the efficiency of translation initiation in sperm cells - Jiao-Jiao Shi; Yuan Cao; Qiu-Hua Lang; Yao Dong; Liu-Yuan Huang; Liu-Jie Yang; Jing-Jing Li; Xue-Xin Zhang; Dan-Yang Wang (Plant Reproduction, 2022)

Identification and analysis of B cell epitopes of hemagglutinin of H1N1 influenza virus - Qing Feng; Xiao-Yan Huang; Yang-Meng Feng; Li-jun Sun; Jing-Ying Sun; Yan Li; Xin Xie; Jun Hu; Chun-Yan Guo (Archives of Microbiology, 2022)

Food irradiation: a promising technology to produce hypoallergenic food with high quality - Xiaowen Pi; Yili Yang; Yuxue Sun; Xibo Wang; Yin Wan; Guiming Fu; Xin Li; Jianjun Cheng (Critical Reviews in Food Science and Nutrition, 2022)

Transcriptomic analysis reveals yolk accumulation mechanism from the hepatopancreas to ovary in the pacific white shrimp Litopenaeus vannamei - Zhi Li; Minyu Zhou; Yao Ruan; Xiaoli Chen; Chunhua Ren; Hao Yang; Xin Zhang; Jinshang Liu; Huo Li; Lvping Zhang; Chaoqun Hu; Ting Chen; et al. (Frontiers in Marine Science, 2022)
The Pacific white shrimp Litopenaeus vannamei is an economically important penaeid species worldwide. Under farming conditions, the full ovarian maturation of L. vannamei generally depends on the combination of artificial ablation of unilateral eyestalk and feeding high-quality natural diets, suggesting that nutrient accumulation is important to ovarian maturation. In this study, we aimed to investigate the gene expression related to nutritional accumulation in L. vannamei during ovarian development by transcriptomic analysis. A total of 52.45 Gb of high-quality transcriptome data were obtained from 8 samples from the hepatopancreas and ovaries from shrimp in gonadal developmental stages I-IV. A total of 23,149 expressed genes were detected, of which 19,852 were known genes and 3,297 were novel genes. Our study found that genes related to amino acid, carbohydrate and lipid metabolism were expressed at higher levels in the hepatopancreas than in the ovary. The genes for most lipoproteins and their receptors were predominantly expressed in the hepatopancreas, while vitellogenin receptor ( VgR ) was specifically expressed in the ovary. Moreover, two vitellogenin ( Vg ) genes were identified, in which one was specifically expressed in the hepatopancreas and defined as Hp-Vg , and the other was specifically expressed in the ovary and defined as Ov-Vg . In addition, genes related to carotenoid metabolism were enriched in the hepatopancreas. This study provides solid evidence that the hepatopancreas is the major exogenous vitellogenesis site for ovarian maturation of L. vannamei . Two distinct Vg genes perform exogenous and endogenous vitellogenesis in the hepatopancreas and ovary in L. vannamei , respectively. The results of this study also presented some new insights for understanding the nutritional dynamics from the hepatopancreas to ovary during ovarian maturation in penaeids.

Activation of the TREK-1 Potassium Channel Improved Cognitive Deficits in a Mouse Model of Alzheimer’s Disease by Modulating Glutamate Metabolism - Fang Li; Shu-ning Zhou; Xin Zeng; Zhen Li; Rui Yang; Xue-xi Wang; Bin Meng; Wei-lin Pei; Li Lu (Molecular Neurobiology, 2022)

Comparative Analysis of Endogenous Hormones and Metabolite Profiles in Early-Spring Flowering Plants and Unflowered Plants Revealing the Strategy of Blossom - Xue Yan; Jia Liu; Ke-Xin Wu; Nan Yang; Li-Ben Pan; Ying Song; Yang Liu; Zhong-Hua Tang (Journal of Plant Growth Regulation, 2022)

Inhibition of visfatin alleviates sepsis-induced intestinal damage by inhibiting Hippo signaling pathway - Zhong-Shen Kuang; Yu-Xin Leng; Ning Yang; Zheng-Qian Li; Ya-Nan Zong; Deng-Yang Han; Yue Li; Jin-Dan He; Xing-Ning Mi; Zhu-Kai Cong; Xi Zhu; Chang-Yi Wu; et al. (Inflammation Research, 2022)
Background The aim of this study is to investigate role of Visfatin, one of the pro-inflammatory adipokines, in sepsis-induced intestinal injury and to clarify the potential mechanism. Methods C57BL/6 mice underwent cecal ligation and puncture (CLP) surgery to establish sepsis model in vivo. Intestinal epithelial cells were stimulated with LPS to mimic sepsis-induced intestinal injury in vitro. FK866 (the inhibitor of Visfatin) with or without XMU-MP-1 (the inhibitor of Hippo signaling) was applied for treatment. The expression levels of Visfatin, NF-κB and Hippo signaling pathways-related proteins were detected by western blot or immunohistochemistry. The intestinal cell apoptosis and intestinal injury were investigated by TUNEL staining and H&E staining, respectively. ELISA was used to determine the production of inflammatory cytokines. Results The expression of Visfatin increased in CLP mice. FK866 reduced intestinal pathological injury, inflammatory cytokines production, and intestinal cell apoptosis in sepsis mice. Meanwhile, FK866 affected NF-κB and Hippo signaling pathways. Additionally, the effects of FK866 on inflammatory response, apoptosis, Hippo signaling and NF-κB signaling were partly abolished by XMU-MP-1, the inhibitor of Hippo signaling. In vitro experiments also revealed that FK866 exhibited a protective role against LPS-induced inflammatory response and apoptosis in intestinal cells, as well as regulating NF-κB and Hippo signaling, whereas addition of XMU-MP-1 weakened the protective effects of FK866. Conclusion In short, this study demonstrated that inhibition of Visfatin might alleviate sepsis-induced intestinal injury through Hippo signaling pathway, supporting a further research on Visfatin as a therapeutic target.

The relationship between short-term PM2.5 exposure and outpatient visits for acne vulgaris in Chongqing, China: a time-series study - Xiang Li; Lai-Xin Zhou; Li-Li Yang; Xiao-Long Huang; Nan Wang; Yue-Gu Hu; En-Jie Tang; Hua Xiao; Yu-Meng Zhou; Ya-Fei Li; Yuan-Gang Lu; Tong-Jian Cai (Environmental Science and Pollution Research, 2022)

Mental health conditions and academic burnout among medical and non-medical undergraduates during the mitigation of COVID-19 pandemic in China - Qian Yang; Yueheng Liu; Winson Fuzun Yang; Pu Peng; Shubao Chen; Yunfei Wang; Xin Wang; Manyun Li; Yingying Wang; Yuzhu Hao; Li He; Qianjin Wang; et al. (Environmental Science and Pollution Research, 2022)
The outbreak of the novel coronavirus disease 2019 (COVID-19) has posed a great impact on people’s mental health, especially for undergraduate students. This study aimed to compare the mental health conditions and academic burnout between medical and non-medical undergraduates in China when the COVID-19 pandemic is mitigating. A cross-sectional online survey was conducted among 4,972 undergraduates between October 2020 and April 2021, when the pandemic was basically under control. The survey included basic demographics information and standardized scales to evaluate depression, anxiety, perceived stress, daytime sleepiness, alcohol abuse/dependence, quality of life, fatigue, and academic burnout. Compared with medical undergraduates, non-medical undergraduates had higher rates of moderate to severe depression symptoms (29.1% vs. 17.9%, P < 0.001), moderate to severe anxiety symptoms (19.7% vs. 8.9%, P < 0.001), alcohol abuse/dependence (16.3% vs.10.3%, P < 0.001), excessive daytime sleepiness (47.4% vs. 43.4%, P = 0.018), high perceived stress (34.7% vs. 22.2%, P < 0.001), high level of fatigue (51.8% vs. 42.2%, P < 0.001), low QOL (35.8% vs. 21.4%, P < 0.001), and higher academic burnout score (59.4 vs. 57.5, P < 0.001). Being non-medical undergraduates, depression, alcohol abuse/dependence, excessive daytime sleepiness, and high perceived stress were positively associated with academic burnout, while high QOL was negatively associated with the burnout (all P < 0.001). Excessive daytime sleepiness was the strongest predictor for academic burnout.

Altered effective connectivity within the cingulo-frontal-parietal cognitive attention networks in chronic low back pain: a dynamic causal modeling study - Cui Ping Mao; Hua Juan Yang; Qiu Juan Zhang; Quan Xin Yang; Xiao Hui Li (Brain Imaging and Behavior, 2022)

Circular RNA circKIF2A Contributes to the Progression of Neuroblastoma Through Regulating PRPS1 Expression by Sponging miR-377-3p - Quan Jin; Jianmu Li; Fan Yang; Lingling Feng; Xin Du (Biochemical Genetics, 2022)

Rs7853346 Polymorphism in lncRNA-PTENP1 and rs1799864 Polymorphism in CCR2 are Associated with Radiotherapy-Induced Cognitive Impairment in Subjects with Glioma Via Regulating PTENP1/miR-19b/CCR2 Signaling Pathway - Sen Yang; Zhan-zhao Fu; Yan-qiu Zhang; Bao-hong Fu; Li-xin Dong (Biochemical Genetics, 2022)

Deepened snow loosens temporal coupling between plant and microbial N utilization and induces ecosystem N losses - Zhou Jia; Ping Li; Yuntao Wu; Pengfei Chang; Meifeng Deng; Luyin Liang; Sen Yang; Chengzhang Wang; Bin Wang; Lu Yang; Xin Wang; Zhenhua Wang; et al. (Global Change Biology, 2022)
Seasonal differences in plant and microbial nitrogen (N) acquisition are believed to be a major mechanism that maximizes ecosystem N retention. There is also a concern that climate change may interrupt the delicate balance in N allocation between plants and microbes. Yet, convincing experimental evidence is still lacking. Using a 15 N tracer, we assessed how deepened snow affects the temporal coupling between plant and microbial N utilization in a temperate Mongolian grassland. We found that microbial 15 N recovery peaked in winter, accounting for 22% of the total ecosystem 15 N recovery, and then rapidly declined during the spring thaw. By stimulating N loss via N 2 O emission and leaching, deepened snow reduced the total ecosystem 15 N recovery by 42% during the spring thaw. As the growing season progresses, the 15 N released from microbial biomass was taken up by plants, and the competitive advantage for N shifted from microbes to plants. Plant 15 N recovery reached its peak in August, accounting for 17% of the total ecosystem 15 N recovery. The Granger causality test showed that the temporal dynamics of plant 15 N recovery can be predicted by microbial 15 N recovery under ambient snow but not under deepened snow. In addition, plant 15 N recovery in August was positively correlated with and best explained by microbial 15 N recovery in March. The lower microbial 15 N recovery under deepened snow in March reduced plant 15 N recovery by 73% in August. Together, our results provide direct evidence of seasonal differences in plant and microbial N utilization that are conducive to ecosystem N retention; however, deepened snow disrupted the temporal coupling between plant–microbial N use and turnover. These findings suggest that changes in snowfall patterns may significantly alter ecosystem N cycling and N‐based greenhouse gas emissions under future climate change. We highlight the importance of better representing winter processes and their response to winter climate change in biogeochemical models when assessing N cycling under global change.

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

Aquapteridospora jiangxiensis, a new aquatic hyphomycetous fungus from a freshwater habitat in China - Su-Qin Peng; Yu-Lin Liu; Jun-En Huang; Xiao-Hong Li; Xin-Yi Yan; Hai-Yan Song; Yang Gao; Zhi-Jun Zhai; Yuan-Qiu Liu; Dian-Ming Hu (Archives of Microbiology, 2022)

Extracellular vesicles derived from human Sertoli cells: characterizations, proteomic analysis, and miRNA profiling - Xiao-Hui Tan; Sheng-Ji Gu; Wen-Jie Tian; Wen-Peng Song; Yang-Yang Gu; Yi-Ming Yuan; Xue-Song Li; Zhong-Cheng Xin; Sae Woong Kim; Rui-Li Guan; Woong Jin Bae (Molecular Biology Reports, 2022)

Effects of nitrogen source and NaCl stress on oil production in Vischeria sp. WL1 (Eustigmatophyceae) isolated from dryland biological soil crusts in China - Yang She; Xiang Gao; Xin Jing; Jing Wang; Yibei Dong; Jinzi Cui; Huidan Xue; Zhengke Li; Derui Zhu (Journal of Applied Phycology, 2022)

Protective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa - Xin Lu; Xisheng Weng; Zheng Li; Bo Yang; Jun Qian; Yue Huang (Inflammopharmacology, 2022)

Dynamics of the Bacterial Community's Soil During the In-Situ Degradation Process of Waste Chicken Feathers - Kun-tai Li; Yong Yang; Shuai-wen Zhang; Xin Cheng (Indian Journal of Microbiology, 2022)

The Association Between Arsenic Metabolism and Hypertension Among Population with Varying Arsenic Exposure Levels in China - Yinqiao Dong; Miao Zhou; Mingming Zhang; Huanhuan Wang; Yao Chen; Xudan Liu; Shuyi Yang; Hong Lang; Guifan Sun; Xin Li (Exposure and Health, 2022)

Numerical evaluation of face masks for prevention of COVID-19 airborne transmission - Jiaxing Liu; Ming Hao; Shulei Chen; Yang Yang; Jian Li; Qi Mei; Xin Bian; Kun Liu (Environmental Science and Pollution Research, 2022)
The COVID-19 pandemic has forced governments around the globe to apply various preventive measures for public health. One of the most effective measures is wearing face masks, which plays a vital role in blocking the transmission of droplets and aerosols. To understand the protective mechanism of face masks, especially in indoor environments, we apply a computational fluid dynamics technique to predict the lifetime of cough droplets. Therefore, we can assess the exposure risk in a ventilated room where an infected individual wears a face mask or not. We focus on the dynamic evaporation and diffusion of droplets in a human-cough process, which is a major cause for the spread of the virus. We find that wearing a face mask can effectively reduce the total mass and Sauter mean diameter of the residual droplets after a single cough. The mass concentration of virus-carrying droplets in the ventilated room decreases by 201, 43,786, and 307,060 times, corresponding to wearing cotton face masks, surgical face masks, and N95 face masks, respectively. However, the maximum travel distance of 80% droplets is insensitive to wearing a face mask or not. Therefore, the residual droplets are widely distributed due to the influence of indoor airflow. Furthermore, we study aerosol exposure risks in different areas of the room and find that high concentrations of aerosols occur in the streamline through an infected individual, especially next to the individual within 1.5 m. This strongly suggests a social distance despite the fact that the majority of droplets are filtered by face masks. This study explains the impact of face masks and airflow on indoor exposure risks and further inspires potential measures for public health, for example, no individuals should sit near the air supply opening.

Effect of electronic cigarette and tobacco smoking on the human saliva microbial community - Xue Wang; Qili Mi; Ji Yang; Ying Guan; Wanli Zeng; Haiying Xiang; Xin Liu; Wenwu Yang; Guangyu Yang; Xuemei Li; Yinshan Cui; Qian Gao (Brazilian Journal of Microbiology, 2022)

Comparative Analysis on the Evolution of Seepage Parameters in Methane Hydrate Production under Depressurization of Clayey Silt Reservoir and Sandy Reservoir - Yaobin Li; Xin Xin; Tianfu Xu; Huixing Zhu; Haibin Wang; Qiang Chen; Bo Yang (Journal of Marine Science and Engineering, 2022)
Gas hydrates are likely to become an important strategic resource with commercial development prospects. It is therefore of great significance to realize the long-term and efficient production of methane hydrate reservoirs. Previous studies have shown that the lithological characteristics of hydrate reservoirs have a significant impact on reservoir productivity by influencing the evolution of seepage parameters in the process of hydrate production. The porosity (Φ) and initial hydrate saturation (SH) affect the amount of hydrate decomposition and pressure transfer, and also indirectly affect the reservoir temperature field. The permeability (k) directly affects the rate of pressure-drop transmission and methane gas discharge. Due to the differences in seepage parameters caused by different reservoir lithology, a sandy hydrate reservoir (SHR) in Japan and a clayey silt hydrate reservoir (CHR) in China were found to have different gas production rates and the spatial evolution characteristics of the temperature and pressure fields varied in gas hydrate production tests. Therefore, to ensure the long-term and efficient production of the CHR in China, two models were established for a comparative analysis based on a numerical simulation. The two models were depressurizing models of the CHR of the W11 drilling site in the Shenhu Sea area of the South China Sea and the SHR of the AT1 drilling site in the Eastern Nankai Trough of Japan. Both models considered the heterogeneity of seepage parameters, and the TOUGH+HYDARATE (T+H) code was used in subsequent calculations. Four key results were obtained: (a) The order of the significance levels of the lithological parameters on productivity was k > SH > Φ in the CHR and SH > k > Φ in the SHR. (b) The heat conduction and heat convection in the CHR were weaker than in the SHR, which made it difficult to recover the low-temperature area caused by hydrate decomposition. (c) The exploitation of a high k hydrate reservoir should be given priority when the other initial conditions were the same in both the CHR and SHR. (d) The exploitation of both the CHR and SHR should not only rely on the hydrate content or seepage capacity to determine the reservoir exploitation potential, but the combined effect of the two parameters should be fully considered.

Noninvasive oral cancer screening based on local residual adaptation network using optical coherence tomography - Wei Yuan; Long Cheng; Jinsuo Yang; Boya Yin; Xingyu Fan; Jing Yang; Sen Li; Jianjun Zhong; Xin Huang (Medical & Biological Engineering & Computing, 2022)

Urinary phthalate metabolites in pregnant women: occurrences, related factors, and association with maternal hormones - Wei Wu; Zhi-li Ma; Fang Yang; Ping Wu; De-xin Zhang; Rong Zeng; Dan-ling Sun; Liu Cao (Environmental Science and Pollution Research, 2022)

Differences of carbon and nitrogen stoichiometry between different habitats in two natural Korean pine forests in Northeast China’s mountainous areas - Ya-fei Wang; Wen-biao Duan; Mei-xue Qu; Li-xin Chen; Hang-yu Lan; Xi-feng Yang; Si-jing Meng; Jia Chen (Journal of Mountain Science, 2022)

Flavonoid glycosides from the nectar of Camellia reticulata Lindl. - Xin-Lan Chen; Xing-Rong Peng; Xue-Yang Gong; Yi-Qiu Liu; Zhuo Qing; Xiao-Xiao Ren; Rui Su; Li-Ming Fang; Ming-Hua Qiu; Kun Dong (Natural Product Research, 2022)

Two new chemical constituents from the rhizomes of Actaea dahurica - Sen-Ju Ma; Hai-Bo Li; Jun-Ran Shao; Qian-Qian Pang; Ting Li; Xin-Sheng Yao; Yang Yu (Natural Product Research, 2022)

Effects of mowing frequency on abundance, genus diversity and community traits of soil nematodes in a meadow steppe in northeast China - F. J. Pan; L. Y. Yang; C. L. Wang; R. R. Yan; C. J. Li; Y. F. Hu; Y. Jiang; J. Cao; H. Y. Tan; X. P. Xin (Plant and Soil, 2022)

CitWRKY28 and CitNAC029 promote the synthesis of cuticular wax by activating CitKCS gene expression in citrus fruit - Hongbin Yang; Zhifeng Zhu; Mingfei Zhang; Xin Li; Rangwei Xu; Feng Zhu; Juan Xu; Xiuxin Deng; Yunjiang Cheng (Plant Cell Reports, 2022)

Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats - Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; Bo-Yuan Fan; Ming-Ming Zhang; Tao Chen; Hui Li; Yang Bai; Yun-Qing Li (Neuroscience Bulletin, 2022)
Central sensitization is essential in maintaining chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. Here, we examined the role of the anterior cingulate cortex (ACC) in the pathogenesis of abdominal hyperalgesia in a rat model of CP induced by intraductal administration of trinitrobenzene sulfonic acid (TNBS). TNBS treatment resulted in long-term abdominal hyperalgesia and anxiety in rats. Morphological data indicated that painful CP induced a significant increase in FOS-expressing neurons in the nucleus tractus solitarii (NTS) and ACC, and some FOS-expressing neurons in the NTS projected to the ACC. In addition, a larger portion of ascending fibers from the NTS innervated pyramidal neurons, the neural subpopulation primarily expressing FOS under the condition of painful CP, rather than GABAergic neurons within the ACC. CP rats showed increased expression of vesicular glutamate transporter 1, and increased membrane trafficking and phosphorylation of the N -methyl-D-aspartate receptor (NMDAR) subunit NR2B and the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) subunit GluR1 within the ACC. Microinjection of NMDAR and AMPAR antagonists into the ACC to block excitatory synaptic transmission significantly attenuated abdominal hyperalgesia in CP rats, which was similar to the analgesic effect of endomorphins injected into the ACC. Specifically inhibiting the excitability of ACC pyramidal cells via chemogenetics reduced both hyperalgesia and comorbid anxiety, whereas activating these neurons via optogenetics failed to aggravate hyperalgesia and anxiety in CP rats. Taken together, these findings provide neurocircuit, biochemical, and behavioral evidence for involvement of the ACC in hyperalgesia and anxiety in CP rats, as well as novel insights into the cortical modulation of painful CP, and highlights the ACC as a potential target for neuromodulatory interventions in the treatment of painful CP.

G-protein coupled receptor 34 regulates the proliferation and growth of LS174T cells through differential expression of PI3K subunits and PTEN - Bo Zuo; Na Wu; Shen Yang; Zhaohui Zhong; Mei Li; Xin Yu; Yulan Liu; Weidong Yu (Molecular Biology Reports, 2022)
Purpose G-protein coupled receptor (GPR 34) has been found to play important roles in some cancers and regulates the proliferation, apoptosis, and migration of these cancer cells. However, the mechanisms underlying how GPR34 functions to regulate growth and proliferation of colorectal cancer cells remains to be clarified. Methods We employed stable GPR34 knockdown LS174T cell models, GPR34 Mab blocking, a CCK-8 kit, and a colony formation assay to characterize the effect of GPR34 on the proliferation of LS174T in vitro and xenograft tumor growth in vivo. The mRNA level of GPR34 was detected by RT-PCR in tumor tissues and adjacent normal tissues from 34 CRC patients. Results Based on RT-PCR results, GPR34 exhibited high level in tumor samples compared with adjacent normal samples. Increased expression of GPR34 is more associated with poor prognosis of CRC as shown in The Cancer Genome Atlas (TCGA) dataset by Kaplan–Meier survival analysis. Furthermore, we showed that GPR34 knockdown inhibited the proliferation of LS174T colon cancer cells and related xenograft tumor growth. Searching for the distinct molecular mechanism, we identified several contributors to proliferation of LS174T colon cancer cells: PI3K subunits/PTEN, PDK1/AKT, and Src/Raf/Ras/ERK. GPR34 knockdown inhibited the proliferation of LS174T cells by upregulating expression of PTEN, and downregulating expression of PI3K subunits p110-beta. Conclusion Our findings provide direct evidence that GPR34 regulates the proliferation of LS174T cells and the growth of LS174T tumor xenografts by regulating different pathways. High expression of GPR34 mRNA could then be used to predict poor prognosis of CRC.

Integrated Proteome and Phosphoproteome Analyses Reveal Early- and Late-Stage Protein Networks of Traumatic Brain Injury - Yutao Huang; Haofuzi Zhang; Erwan Yang; Kangyi Yue; Xiangyu Gao; Shuhui Dai; Jialiang Wei; Yuefan Yang; Peng Luo; Xin Li; Xiaofan Jiang (Journal of Molecular Neuroscience, 2022)

Protocatechuic acid protects mice from influenza A virus infection - Qian Wang; Xiaojuan Ren; Jinhua Wu; Hongrong Li; Liu Yang; Yan Zhang; Xin Wang; Zhicun Li (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Alternaria species causing leaf spot on hemp (Cannabis sativa) in Northern China - Hong Cheng; Lin Zhao; Xin Wei; Xi Liu; Guo-Yang Gao; Jian-Xin Deng; Mei-Jia Li (European Journal of Plant Pathology, 2022)

Short-term effect of ambient air pollutant change on the risk of tuberculosis outpatient visits: a time-series study in Fuyang, China - Xin-Qiang Wang; Ying-Qing Li; Cheng-Yang Hu; Kai Huang; Kun Ding; Xiao-Jing Yang; Xin Cheng; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Yong-Zhong Zhang; Zhen-tao Ding; et al. (Environmental Science and Pollution Research, 2022)

Study of osmoadaptation mechanisms of halophilic Halomonas alkaliphila XH26 under salt stress by transcriptome and ectoine analysis - Tiantian Zhang; Xin Zhang; Yongzhen Li; Ning Yang; Lijuan Qiao; Zengqiang Miao; Jiangwa Xing; Derui Zhu (Extremophiles, 2022)

Hypobaric hypoxia triggers pyroptosis in the retina via NLRP3 inflammasome activation - Xiaorong Xin; Kun Yang; Haiping Liu; Yanrong Li (Apoptosis, 2022)

The Predictability of Ocean Environments that Contributed to the 2020/21 Extreme Cold Events in China: 2020/21 La Niña and 2020 Arctic Sea Ice Loss - Fei Zheng; Ji-Ping Liu; Xiang-Hui Fang; Mi-Rong Song; Chao-Yuan Yang; Yuan Yuan; Ke-Xin Li; Ji Wang; Jiang Zhu (Advances in Atmospheric Sciences, 2022)
Several consecutive extreme cold events impacted China during the first half of winter 2020/21, breaking the low-temperature records in many cities. How to make accurate climate predictions of extreme cold events is still an urgent issue. The synergistic effect of the warm Arctic and cold tropical Pacific has been demonstrated to intensify the intrusions of cold air from polar regions into middle-high latitudes, further influencing the cold conditions in China. However, climate models failed to predict these two ocean environments at expected lead times. Most seasonal climate forecasts only predicted the 2020/21 La Niña after the signal had already become apparent and significantly underestimated the observed Arctic sea ice loss in autumn 2020 with a 1–2 month advancement. In this work, the corresponding physical factors that may help improve the accuracy of seasonal climate predictions are further explored. For the 2020/21 La Niña prediction, through sensitivity experiments involving different atmospheric–oceanic initial conditions, the predominant southeasterly wind anomalies over the equatorial Pacific in spring of 2020 are diagnosed to play an irreplaceable role in triggering this cold event. A reasonable inclusion of atmospheric surface winds into the initialization will help the model predict La Niña development from the early spring of 2020. For predicting the Arctic sea ice loss in autumn 2020, an anomalously cyclonic circulation from the central Arctic Ocean predicted by the model, which swept abnormally hot air over Siberia into the Arctic Ocean, is recognized as an important contributor to successfully predicting the minimum Arctic sea ice extent.

Isolated intracranial xanthogranuloma involving the Meckel’s cave in an adult: a case report - Yang Wen; Yu-mei Li; Biao Zhu; Xin Liu; Ming Zhao (Acta Neurologica Belgica, 2022)

Baicalin attenuates amyloid β oligomers induced memory deficits and mitochondria fragmentation through regulation of PDE-PKA-Drp1 signalling - Hai-Yang Yu; Ye Zhu; Xin-Li Zhang; Lei Wang; Yan-Meng Zhou; Fang-Fang Zhang; Han-Ting Zhang; Xiao-Min Zhao (Psychopharmacology, 2022)

Long Non-coding RNA GAS5 Knockdown Attenuates H2O2-Induced Human Trabecular Meshwork Cell Apoptosis and Promotes Extracellular Matrix Deposition by Suppressing miR-29b-3p and Upregulating STAT3 - Jia Meng; Xin Yang; Xuetao Huang; Qiuming Li (Journal of Molecular Neuroscience, 2022)

Neuroprotective effect of aldose reductase knockout in a mouse model of spinal cord injury involves NF-κB pathway - Fu-xin Han; Rui Zhang; Xin-xing Yang; Shan-bo Ma; Shi-jie Hu; Bing Li (Experimental Brain Research, 2022)

Using Caenorhabditis elegans to assess the ecological health risks of heavy metals in soil and sediments around Dabaoshan Mine, China - Xin Li; Qingqing Yang; Ling Wang; Chuxin Song; Lufeng Chen; Jie Zhang; Yong Liang (Environmental Science and Pollution Research, 2022)

Cumulative damage effect on debris slopes under frequent microseisms - Zhong-ping Yang; Shi-qi Li; Xin Tian; Yuan-xin Hu; Wan-kun Li (Journal of Mountain Science, 2022)

The Linkage between Midwinter Suppression of the North Pacific Storm Track and Atmospheric Circulation Features in the Northern Hemisphere - Minghao Yang; Chongyin Li; Xin Li; Xiong Chen; Lifeng Li (Advances in Atmospheric Sciences, 2022)

Multilocus species delimitation and phylogeny of the genus Calommata (Araneae, Atypidae) in southern China - Fan Li; Xin Xu; Zengtao Zhang; Fengxiang Liu; Zizhong Yang; Daiqin Li (Zoologica Scripta, 2022)
Species delimitation is critical to our understanding of evolution, biodiversity, and conservation. However, delimiting species boundaries can be challenging, especially when intraspecific divergence is high (and interspecific divergence is low), and gene flow and incomplete lineage sorting are present. Mygalomorph spiders have become models for examining a variety of evolutionary and biogeographical questions. However, their extreme morphological homogeneity and high genetic structuring make delimiting mygalomorph species especially challenging. Integrative approaches to species delimitation, which combine multiple lines of evidence, have been used to infer the limits of many mygalomorph groups in an independent and reproducible way. Yet molecular species delimitation and phylogenetic relationships of the purseweb spider family Atypidae remain scarce. In this study, we explored the phylogeny and species delimitation of Calommata spiders from southern China using data sets including three mitochondrial ( COI , 16S , and 12S ) and two nuclear ( 28S , H3 ) markers. Our phylogenetic analyses yielded a well‐supported clade containing all southern Chinese Calommata and a sister relationship between C . signata and three new species within it. Based on the single‐locus and multilocus species delimitation analyses, we delimited four Calommata species from southern China: one known species ( C . signata ) and three new species ( C . yuanjiangica sp. n., C . hangzhica sp. n. and C . jinggangica sp. n.). This study thus provides a framework for determining the limits of C . signata sensu lato species and calls for further study of systematics and evolutionary relationships within Calommata and other atypid lineages.

Transformation of fertilizer nitrogen in fluvo-aquic soils with different textures and its influencing factors - Shijie Ding; Xiuli Xin; Wenliang Yang; Xianfeng Zhang; Anning Zhu; Shaomin Huang; Jiao Yang; Guocui Ren; Mengrou Li (Plant and Soil, 2022)

Review of Metabolomics-Based Biomarker Research for Parkinson’s Disease - Xin Li; Xiaoying Fan; Hongtian Yang; Yufeng Liu (Molecular Neurobiology, 2022)

Comparative Transcriptome Analysis of Spleen Reveals Potential Regulation of Genes and Immune Pathways Following Administration of Aeromonas salmonicida subsp. masoucida Vaccine in Atlantic Salmon (Salmo salar) - Qiang Fu; Yuqing Li; Hao Zhang; Min Cao; Lu Zhang; Chengbin Gao; Xin Cai; Defeng Chen; Ziying Yang; Jie Li; Ning Yang; Chao Li (Marine Biotechnology, 2022)

Effects of protein oxidation, cathepsins, and various freezing temperatures on the quality of superchilled sturgeon fillets - Nana Zhao; Xianqing Yang; Yujin Li; Haohao Wu; Yiping Chen; Ruichang Gao; Feng Xiao; Fan Bai; Jinlin Wang; Zunying Liu; Xin Gao; Yuanhui Zhao (Marine Life Science & Technology, 2022)

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss) - Hui-Xia Yu; Yang Li; Wei-Jia Song; Hui Wang; Hao-Lin Mo; Qiao Liu; Xin-Miao Zhang; Ze-Bin Jiang; Li-Xin Wang (Fish Physiology and Biochemistry, 2022)

Associations between ambient fine particulate (PM2.5) exposure and cardiovascular disease: findings from the China Health and Retirement Longitudinal Study (CHARLS) - Xiaowei Mai; Houfeng Zhou; Yangyang Li; Xin Huang; Tao Yang (Environmental Science and Pollution Research, 2022)

Two new iridoid glycosides from the fruit of Gardenia jasminoides - Hai-Bo Li; Jin-Feng Ma; Yu-Dan Mei; Ling-Xian Liu; Ze-yu Cao; Dan-Feng Shi; Xin-Sheng Yao; Yang Yu (Natural Product Research, 2022)

Genetic diversity of Lathyrus sp collected from different geographical regions - Md. Mosiur Rahman; Md. Ruhul Quddus; Md. Omar Ali; Rong Liu; Mengwei Li; Xin Yan; Guan Li; Yishan Ji; Md. Monoar Hossain; Chenyu Wang; Ashutosh Sarker; Tao Yang; et al. (Molecular Biology Reports, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

The expression and interaction proteins analysis of BjuFKF1/LKP2 in B. juncea - Jing Zeng; Anran Wu; Yuemin Yang; Liang Zhao; Li Chen; Chuanqi Wang; Xin Yang; Yanping Chen; Shiyan Liu; Pei Luo; Junli Wang (Molecular Genetics and Genomics, 2022)

Circular RNA screening identifies circMYLK4 as a regulator of fast/slow myofibers in porcine skeletal muscles - Haigang Cao; Jieming Liu; Tianning Du; Yihao Liu; Xiaoyu Zhang; Yuan Guo; Jie Wang; Xiaomin Zhou; Xiao Li; Gongshe Yang; Xin’e Shi (Molecular Genetics and Genomics, 2022)
The type of myofiber is related to the quality of meat. The slow oxidized myofiber helps to increase the tenderness and juiciness of muscle. Numerous studies have shown that circRNA plays a key role in skeletal muscle development. However, the role of circRNA in porcine skeletal myofiber types is unclear. In this study, we performed high-throughput RNA sequencing to study the differential expression of circRNA in the longissimus dorsi and the soleus muscle. A total of 40,757 circRNAs were identified, of which 181 were significantly different. Interestingly, some circRNAs were involved in metabolism pathways, AMPK, FoxO, and PI3K-Akt signaling pathways. Besides, we focused on a novel circRNA-circMYLK4. By injecting circMYLK4-AAV into piglets, we found that circMYLK4 significantly increased the mRNA and protein levels of the slow muscle marker genes. In summary, our study laid an essential foundation for further research of circRNA in myofiber type conversion and higher meat quality.

Comparison of the effects of three fungicides on clubroot disease of tumorous stem mustard and soil bacterial community - Jingjing Liao; Luyun Luo; Li Zhang; Lingzhi Wang; Xuedan Shi; Hao Yang; Shenghua Tan; Lei Tan; Xin Liu; Diandong Wang; Zhenchuan Mao (Journal of Soils and Sediments, 2022)
Purpose The application of fungicides is one of the main strategies to prevent clubroot disease. Currently, numerous studies focus on changes in the soil microbial community at different levels of clubroot disease severity. However, the effects of fungicides on the soil microbial community and causative pathogen, Plasmodiophora brassicae , while preventing clubroot disease remain unclear. Methods In this study, we evaluated the control efficacy of three fungicides (fluazinam, metalaxyl-mancozeb, and carbendazim) on clubroot disease of tumorous stem mustard in greenhouse experiment. Uninoculated and Water treatments after inoculation were performed as controls. At three (3 W) and six weeks (6 W) post-inoculation of P. brassicae , soil properties, bacterial composition (sequencing of 16S rRNA genes), and effector gene expression of the pathogen were analyzed. The correlation of these factors with disease index (DI) was explored. Results Fluazinam was the most effective in controlling clubroot disease of tumorous stem mustard with a controlled efficacy of 59.81%, and the abundance of P. brassicae in the soil decreased 21.29% after 3 weeks of treatment. Compared with other treatments, twelve out of twenty effector genes showed higher expression in fluazinam 3 W samples. Different fungicides had different effects on soil properties. EC (electrical conductivity), the main factor that positively associated with DI, was significantly lower in fluazinam treatment than the other two fungicide treatments. The application of fungicides, especially carbendazim, significantly reduced bacterial α-diversity and the composition of soil bacteria. Pseudomonas , Microbacterium , and Sphingobacterium (positively correlated with DI) were enriched in Water, metalaxyl-mancozeb, and carbendazim treatments, but were less abundant in fluazinam treatment. Among the three fungicide treatments, DI was significantly negatively correlated with Shannon and Chao 1 indices. Soil properties and the top bacterial genera that positively correlated with DI were influenced to a lesser degree in the fluazinam treatment. Conclusion Among three fungicides, fluazinam was the most effective agent with the highest control effects against clubroot disease. The strong virulence of fluazinam against P. brassicae was one of the main reasons for the prevention of clubroot disease, and in addition the alteration of rhizosphere bacterial community by fluazinam to the detriment of P. brassicae infection. Based on our results, EC could be an indicator of the severity of clubroot disease.

Scalp Acupuncture Protects Against Neuronal Ferroptosis by Activating The p62-Keap1-Nrf2 Pathway in Rat Models of Intracranial Haemorrhage - Ming-Yue Li; Xiao-Hong Dai; Xue-Ping Yu; Wei Zou; Wei Teng; Peng Liu; Xin-Yang Yu; Qi An; Xin Wen (Journal of Molecular Neuroscience, 2022)
Intracerebral haemorrhage (ICH) can be a catastrophic event; even if the initial stages of the pathology were well-managed, a number of patients experience varied residual neurological deficits following the insult. Ferroptosis is a recently identified type of cell demise which is tightly linked to the neurological impairment associated with ICH. In the current work, the prophylactic impact of scalp acupuncture (SA) therapy on autologous blood injection murine models of ICH was investigated in order to establish whether SA could mitigate the secondary damage arising following ICH by moderating ferroptosis. The pathophysiological mechanisms associated with this process were also explored. Ludmila Belayev tests were utilised for the characterisation of neurological damage. Haematoxylin–eosin staining was employed in order to determine the cerebral impact of the induced ICH. Malondialdehyde (MDA) and iron titres in peri-haemorrhagic cerebral tissues were appraised using purchased assay kits. Transmission electron microscopy delineated mitochondrial appearances within nerve cell bodies from the area of haemorrhage. Western blotting techniques were utilised to assay the degree of protein expression of NeuN, sequestosome 1 (p62), nuclear factor erythroid 2-related factor 2 (Nrf2), Kelch-like ECH-associated protein 1 (Keap1), glutathione peroxidase 4 (GPX4) and ferritin heavy chain 1 (FTH1). The frequencies of Nrf2, GPX4 and FTH1 positive cells, respectively, were documented with immunohistochemical staining. The results demonstrated that therapy with SA after ICH mitigated MDA and iron sequestration, diminished the appearance of contracted mitochondria with increased outer mitochondrial membrane diameter within the nerve cell bodies, and suppressed neuronal ferroptosis. The pathways responsible for these effects may encompass amplified p62, Nrf2, GPX4 and FTH1 expression, together with decreased Keap1 expression. Application of SA reduced identified neurobehavioural abnormalities after ICH; no disparities were observed between the consequences of SA therapy and deferoxamine delivery. It can be surmised that intervention with SA enhanced recovery after ICH by triggering the antioxidant pathway, p62/Keap1/Nrf2, and causing FTH1 and GPX4 upregulation, factors that participate in diminishing excess iron and thus in mitigating lipid peroxidation insults arising from ferroptosis following ICH.

HMGB1-RAGE Pathway Contributes to the Abnormal Migration of Endogenous Subventricular Zone Neural Progenitors in an Experimental Model of Focal Microgyria - Yi-Wen Mei; Tian-Lan Huang; Xin Chen; Si-Xun Yu; Jie Li; Zhi Zhang; Yang He; Da-qing Guo; Hai-Feng Shu (Journal of Molecular Neuroscience, 2022)