Progress on Offshore Wind Farm Dynamic Wake Management for Energy - Liye Zhao; Lei Xue; Zhiqian Li; Jundong Wang; Zhichao Yang; Yu Xue (Journal of Marine Science and Engineering, 2022)
The wake management of offshore wind farms (OWFs) mainly considers the wake effect. Wake effects commonly occur in offshore wind farms, which cause a 5–10% reduction in power production. Although there have been many studies on wake management, many methods are not accurate enough; for instance, look-up table and static wake model control methods do not consider the time-varying wake state. Dynamic wake management is based on the real-time dynamic wake, so it can increase the energy of the OWFs effectively. For OWFs, dynamic wake control is the main method of dynamic wake management. In this paper, the existing wake model and control progress are discussed, mainly emphasizing the dynamic wake model and the dynamic wake control method, solving the gap of the review for dynamic wake management. This paper presents a digital twins (DT) framework for power and fatigue damage for the first time.. The structure of this paper is as follows: (1) the mechanism of wind farm wake interference is described and then the dynamic wake model is reviewed and summarized; (2) different control methods are analyzed and the dynamic wake management strategies for different control methods are reviewed; (3) in order to solve the problems of dynamic wake detection and real-time effective control, the technology of DT is applied to the dynamic wake control of OWFs. This new DT frame has a promising application prospect in improving power and reducing fatigue damage.

Ice-Water-Gas Interaction during Icebreaking by an Airgun Bubble - Qi-Gang Wu; Zuo-Cheng Wang; Bao-Yu Ni; Guang-Yu Yuan; Yuriy A. Semenov; Zhi-Yuan Li; Yan-Zhuo Xue (Journal of Marine Science and Engineering, 2022)
When an airgun releases high-pressure gas underwater below an ice plate, it is observed that a bubble is formed rapidly while the ice plate is broken fiercely. In order to study the ice-water-gas interaction during this transient and violent phenomenon, a set of laboratory-scale devices was designed and a series of icebreaking experiments were carried out. High-speed photography was used to capture the evolution of the bubble and the ice plate. It was found that the airgun bubble had a unique ‘pear’ shape compared with the spherical bubble generated by electric sparking. The pressure induced by the pulsation of the airgun bubble near a rigid wall was measured by the pressure sensor. The initial shockwave, oscillatory pressure peaks caused by the directional fast air injection, secondary shockwave, and pressure peak caused by the bubble jet impact were clearly recorded. Three damage patterns of ice plates were observed and corresponding reasons were analyzed. The influence of dimensionless parameters, such as airgun-ice distance H and ice thickness T, was also investigated. The physical mechanism of ice-water-gas interaction was summarized.

Functional analysis of HADH c.99C>G shows that the variant causes the proliferation of pancreatic islets and leu-sensitive hyperinsulinaemia - Wu Long; Yue-Bing Wang; Peng-Fei Qu; Lin Ma; Si-Jie Wei; Yan-Mei Xi; Jin-Liang Du; Xue Tang; Kai Liu; Yu-Hua Li; Pu-Ping Lei (Journal of Genetics, 2022)

Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia - Kang-Wei Qian; Yun-Yun Li; Xiao-Hua Wu; Xue Gong; Ai-Lin Liu; Wen-Hao Chen; Zhe Yang; Ling-Jie Cui; Yun-Feng Liu; Yuan-Yuan Ma; Chen-Xi Yu; Furong Huang; et al. (Neuroscience Bulletin, 2022)

Potential antibacterial and anti-biofilm effects of Anoectochilus roxburghii rhizome cultures - Ming-Zhi Fan; Xiao-Long Jiang; Xuan-Chun Piao; Xue-Feng Li; Mei-Yu Jin; Mei-Lan Lian (Journal of Plant Biochemistry and Biotechnology, 2022)

A Rapid Near-Infrared Fluorescent Probe for Cysteine Based on Isophorone and its Application in B16 Cell Imaging - Yan-Ya Wang; Xue-Shuang Yu; Xin-Jie Li; Hong-Bo Liu; Xi Zhu; Ya-Wen Wang; Yu Peng (Journal of Fluorescence, 2022)

Catalytic effect of cesium on the oxidation behavior of cation exchange resins in Li2CO3-Na2CO3-K2CO3 melt - Yang-Hai Zheng; Yong-De Yan; Yun Xue; Yue-Lin Wang; Xin Liu; Wan-Sheng Mi; Qing-Guo Zhang; Yu Li; Fu-Qiu Ma; Mi-Lin Zhang; Zhi-Hao Gan; Kai Zhu (Environmental Science and Pollution Research, 2022)

The Structure and Function of Microbial Community in Rhizospheric Soil of American Ginseng (Panax quinquefolius L.) Changed with Planting Years - Guozhong Chen; Ying Xue; Xin Yu; Chongwei Li; Yuping Hou; Hongwei Zhu; Linlin Jiang; Weibo Zheng; Zhibin Feng; Youzhi Li; Wenli Tang; Xiaoyu Zhao; et al. (Current Microbiology, 2022)

Numerical Simulation of an Air-Bubble System for Ice Resistance Reduction - Bao-Yu Ni; Hongyu Wei; Zhiyuan Li; Bin Fang; Yanzhuo Xue (Journal of Marine Science and Engineering, 2022)
Ships sailing through cold regions frequently encounter floe ice fields. An air-bubble system that reduces friction between the hull and ice floes is thus considered useful for the reduction of ice-induced resistance. In this study, a numerical analysis procedure based on coupled finite volume method (FVM) and discrete element method (DEM) is proposed to simulate complicated hull-water-gas-ice interactions for ice-going ships installed with air-bubble systems. The simulations reveal that after turning on the air-bubble system ice floes in contact with the hull side wall are pushed away from the hull by the gas-water mixture, resulting in an ice-free zone close to the side hull. It is found that the drag reduction rate increases with the increase of ventilation, while the bow ventilation plays a deciding role in the overall ice-resistance reduction. The proposed procedure is expected to facilitate design of new generations of ice-going ships.

Sugar Product Diversification and Its Opportunities in China - Qi Wang; Cai-Feng Xie; Chang-Rong Shi; Yuan Li; Yu-Hao Shang; Chu-Xuan Hou; Fang-Xue Hang; Jian-Bin Li; Kai Li (Sugar Tech, 2022)

RETRACTED ARTICLE: Have international remittance inflows degraded environmental quality? A carbon emission mitigation analysis for Ghana - Kaodui Li; Xiangmiao Wang; Mohammed Musah; Yi Ning; Muntasir Murshed; Morrison Alfred; Zhen Gong; Han Xu; Xinyi Yu; Xue Yang; Keying Shao; Li Wang (Environmental Science and Pollution Research, 2022)

Tumor cell-derived exosome RNF126 affects the immune microenvironment and promotes nasopharyngeal carcinoma progression by regulating PTEN ubiquitination - Changyun Yu; Binbin Xue; Jinying Li; Qianqian Zhang (Apoptosis, 2022)

Transition between Mycobacterium tuberculosis and nontuberculous mycobacteria in recurrent “tuberculosis” patients - Qing Li; Haoran Li; Jun An; Xuxia Zhang; Wei Wang; Yufeng Wang; Zhongtan Xue; Shanshan Li; Yu Pang (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Three new sesquiterpene lactones from the whole plants of Elephantopus scaber - Ding-Chai Lin; Qing Tang; Xue-Fang Zhuo; Wen-Zhi Wang; Can-Jie Li; Guang-Kai Kuang; Zhong-Nan Wu; Yu-Bo Zhang; Guo-Cai Wang; Yao-Lan Li (Natural Product Research, 2022)

Knockdown of Two Iodothyronine Deiodinase Genes Inhibits Epinephrine-Induced Larval Metamorphosis of the Hard-Shelled Mussel Mytilus coruscus - Xue Shi; Yu-Qing Wang; Yue-Ming Yang; Yi-Feng Li (Frontiers in Marine Science, 2022)
The metamorphosis process is a critical life-changing event for marine invertebrate planktonic larvae to transform into benthic adults, which is crucial for the shellfish bed’s ecosystem stability and seed production in aquaculture. The mechanism of neuroendocrine regulation in the larval metamorphosis of bivalves remains ambiguous. In the present study, the expression of two deiodinase genes, McDx and McDy , was analyzed by whole-mount in situ hybridization at four larval stages in the hard-shelled mussel Mytilus coruscus . The McDx and McDy localized in visceral tissues, nervous system, mantle, and velum, indicating that two deiodinase genes are essential for larval development in M. coruscus . Knockdown of the McDx and McDy in the pediveliger larvae of M. coruscus using electroporation of siRNA significantly ( p < 0.001) reduced McDx and McDy expression. McDx and McDy knockdown reduced larval metamorphosis in 45% and 49% of the pediveliger larvae induced by epinephrine (EPI). It is hypothesised that the knockdown effects of McDx and McDy repress metamorphic induction rather than larval viability, which does not elicit a lethal effect. The present study corroborates a synergistic action of the adrenergic and thyroid hormones signalling pathway in M. coruscus , and suggests the role of McDx and McDy in larval development and metamorphic transition.

Experimental study on the effects of particle grading on lime-treated slurry with vacuum preloading - Hong-lei Sun; Zhen-qi Weng; Xue-yu Geng; Meng-fen Shen; Xiao-dong Pan; Li Shi; Yuan-qiang Cai (Marine Georesources & Geotechnology, 2022)

Recent advances in RNA structurome - Bingbing Xu; Yanda Zhu; Changchang Cao; Hao Chen; Qiongli Jin; Guangnan Li; Junfeng Ma; Siwy Ling Yang; Jieyu Zhao; Jianghui Zhu; Yiliang Ding; Xianyang Fang; et al. (Science China Life Sciences, 2022)

Pharmacokinetics of benapenem for injection in subjects with mild to moderate renal impairment - Haijing Yang; Min Zhang; Yuancheng Chen; Hong Ren; Hong Zhang; Chen Yu; Jianda Lu; Li You; Jicheng Yu; Hong Liang; Cuilan Xiao; Zishuang He; et al. (European Journal of Clinical Pharmacology, 2022)

CD146 as a promising therapeutic target for retinal and choroidal neovascularization diseases - Bai Xue; Ping Wang; Wenzhen Yu; Jing Feng; Jie Li; Rulian Zhao; Zhenglin Yang; Xiyun Yan; Hongxia Duan (Science China Life Sciences, 2022)

The long non-coding RNA LIMT inhibits metastasis of hepatocellular carcinoma and is suppressed by EGF signaling - Yu Hu; Hao Li; Hongwei Zhang; Qiang Tang; Guangtan Zhang; Xiqing Li; Fei Xue (Molecular Biology Reports, 2022)
Background The long non-coding RNA LIMT (lncRNA inhibiting metastasis) acts as a tumor suppressor factor in some cancers. However, the biological role of LIMT in hepatocellular carcinoma (HCC) has not been explored. Methods and Results Quantitative real-time PCR was performed to evaluate the expression of LIMT in HCC tissue. The effects of LIMT on tumor growth and metastasis were assessed by in vitro experiments, including colony formation and transwell assays, and in vivo in nude mouse models. Western blot analysis was used to evaluate the expression levels of proteins associated with epithelial-mesenchymal transition (EMT). LIMT expression was significantly lower in HCC than in normal liver tissue. Functionally, overexpression of LIMT repressed the proliferation, invasion, and EMT of HCC cells, while LIMT knockdown increased proliferation, invasion, and EMT of HCC cells in vitro . Furthermore, LIMT overexpression suppressed HCC growth and metastasis while silencing of LIMT had an opposite effect in vivo . Finally, LIMT overexpression reversed EGF-induced EMT. Conclusions Our results suggest that LIMT could play an anti-cancer effect in HCC and might be a potential novel therapeutic target in HCC.

Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat - Dong Peng; Han-Zi Qiao; Hong-Yu Tan; Yi-Xue Wang; Dan Luo; Li-Jun Qiao; Ye-Feng Cai; Shi-Jie Zhang; Qi Wang; Li Guan (Metabolic Brain Disease, 2022)

Local production, downward and regional transport aggravated surface ozone pollution during the historical orange-alert large-scale ozone episode in eastern China - Yibo Zhang; Shaocai Yu; Xue Chen; Zhen Li; Mengying Li; Zhe Song; Weiping Liu; Pengfei Li; Xiaoye Zhang; Eric Lichtfouse; Daniel Rosenfeld (Environmental Chemistry Letters, 2022)

A novel large-scale land degradation remote sensing index and its application in Three River Source Region - Ye Wen; Qiubing Wang; Bing Guo; Chao Meng; Yumei Cai; Haorun Xue; Huihui Zhao; Wenqian Zang; Cuixia Wei; Yang Yu; Yifeng Liu; Jialin Li (Earth Science Informatics, 2022)

Aberrant Gene Expression of Selenoproteins in Chicken Spleen Lymphocytes Induced by Mercuric Chloride - Jia-Hong Chu; Yu-Xue Yan; Xue-Wei Chen; Pei-Chao Gao; Lan-Xin Li; Rui-Feng Fan (Biological Trace Element Research, 2022)

Alternate freezing and thawing enhanced the sediment and nutrient runoff loss in the restored soil of the alpine mining area - Fa-Yong Li; Ren-jie Luo; Yong-jun You; Xue-fei Hu; Xiao-yan Qian; Peng-yan Zhang; Shan Wang; Guo-yu Li; Mohamed Eltohamy Kamel (Journal of Mountain Science, 2022)

Geochemical and Zircon Hf-O Isotopic Constraints on the Origin of Wulian A-Type Granite in Shandong Peninsula, Eastern China - Shuai Yuan; He Li; Lipeng Zhang; Congying Li; Haiyang Liu; Ying-Yu Xue; Weidong Sun (Journal of Earth Science, 2022)

Quinoline, with the active site of 8‐hydroxyl, efficiently inhibits Micropterus salmoides rhabdovirus (MSRV) infection in vitro and in vivo - Bo‐Yang Li; Fei Yang; Zhong‐Yu Zhang; Yu‐Feng Shen; Tao Wang; Liang Zhao; Jia‐Cheng Qin; Fei Ling; Gao‐Xue Wang (Journal of Fish Diseases, 2022)
Micropterus salmoides rhabdovirus (MSRV) is an significant pathogen that causes high mortality and related economic losses in bass aquaculture. There is no effective or approved therapy to date. In this study, we evaluated the anti‐MSRV effects of 22 quinoline derivatives in grass carp ovary (GCO) cells. Among these compounds, 8‐hydroxyquinoline exhibited valid inhibition in decreasing MSRV nucleoprotein gene expression levels of 99.3% with a half‐maximal inhibitory concentrations (IC 50 ) value of 4.66 μM at 48 h. Moreover, 8‐hydroxyquinoline significantly enhanced a protective effect in GCO cells by reducing the cytopathic effect (CPE). By comparing the anti‐MSRV activity of 22 quinoline derivatives, we found that 8‐hydroxyquinoline possessed the efficient active site of 8‐hydroxyl and inhibited MSRV infection in vitro. For in vivo studies, 8‐hydroxyquinoline via intraperitoneal injection exhibited an antiviral effect in MSRV‐infected largemouth bass by substantially enhancing the survival rate by 15.0%. Importantly, the viral loads in the infected largemouth bass notably reduced in the spleen on the third days post‐infection. Overall, 8‐hydroxyquinoline was considered to be an efficient agent against MSRV in aquaculture.

Bacterial microbiota analysis demonstrates that ticks can acquire bacteria from habitat and host blood meal - Si-Si Li; Xiao-Yu Zhang; Xue-Jiao Zhou; Kai-Li Chen; Abolfazl Masoudi; Jing-Ze Liu; Yan-Kai Zhang (Experimental and Applied Acarology, 2022)

Differences of carbon and nitrogen stoichiometry between different habitats in two natural Korean pine forests in Northeast China’s mountainous areas - Ya-fei Wang; Wen-biao Duan; Mei-xue Qu; Li-xin Chen; Hang-yu Lan; Xi-feng Yang; Si-jing Meng; Jia Chen (Journal of Mountain Science, 2022)

Correction to: Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Design, Characterization, and Evaluation of Diosmetin-Loaded Solid Self-microemulsifying Drug Delivery System Prepared by Electrospray for Improved Bioavailability - Zhengqing Gu; Yuanyuan Xue; Shuang Li; Michael Adu-Frimpong; Ying Xu; Jiangnan Yu; Ximing Xu; Yuan Zhu (AAPS PharmSciTech, 2022)

Metagenomic insights into the environmental adaptation and metabolism of Candidatus Haloplasmatales, one archaeal order thriving in saline lakes - Heng Zhou; Dahe Zhao; Shengjie Zhang; Qiong Xue; Manqi Zhang; Haiying Yu; Jian Zhou; Ming Li; Sumit Kumar; Hua Xiang (Environmental Microbiology, 2022)
Summary The KTK 4A‐related Thermoplasmata thrives in the sediment of saline lakes; however, systematic research on its taxonomy, environmental adaptation and metabolism is lacking. Here, we detected this abundant lineage in the sediment of five artificially separated ponds (salinity 7.0%–33.0%) within a Chinese soda‐saline lake using culture‐independent metagenomics and archaeal 16S rRNA gene amplicons. The phylogenies based on the 16S rRNA gene, and 122 archaeal ubiquitous single‐copy proteins and genome‐level identity analyses among the metagenome‐assembled genomes demonstrate this lineage forming a novel order, Candidatus Haloplasmatales, comprising four genera affiliated with the identical family. Isoelectric point profiles of predicted proteomes suggest that most members adopt the energetically favourable ‘salt‐in’ strategy. Functional prediction indicates the lithoheterotrophic nature with the versatile metabolic potentials for carbohydrate and organic acids as well as carbon monoxide and hydrogen utilization. Additionally, hydrogenase genes hdrABC ‐ mvhADG are linked with incomplete reductive citrate cycle genes in the genomes, suggesting their functional connection. Comparison with the coupling of HdrABC‐MvhADG and methanogenesis pathway provides new insights into the compatibility of laterally acquired methanogenesis with energy metabolism in the related order Methanomassiliicoccales . Globally, our research sheds light on the taxonomy, environmental adaptative mechanisms, metabolic potentials and evolutional significance of Ca . Haloplasmatales.

Effects of PHD and HSP90 on erythropoietin production in yak (Bos grunniens) renal interstitial fibroblast-like cells under hypoxia - Yan Cui; Hui Li; Si-Jiu Yu; Seth Yaw Afedo; Xue-Feng Bai (Journal of Molecular Histology, 2022)

Analysis of genotype–phenotype relationships in 90 Chinese probands with Waardenburg syndrome - Guojian Wang; Xiaohong Li; Xue Gao; Yu Su; Mingyu Han; Bo Gao; Chang Guo; Dongyang Kang; Shasha Huang; Yongyi Yuan; Pu Dai (Human Genetics, 2022)

Phthalate’s multiple hormonal effects and their supplementary dietary regulation scheme of health risks for children - Zhenzhen Han; Jiaqi Xue; Yu Li (Environmental Science and Pollution Research, 2022)

Abnormal functional connectivity of the salience network in insomnia - Yongxin Cheng; Ting Xue; Fang Dong; Yiting Hu; Mi Zhou; Xiaojian Li; Ruoyan Huang; Xiaoqi Lu; Kai Yuan; Dahua Yu (Brain Imaging and Behavior, 2022)

Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra) - Li-Chao Pan; Yang-Yang Sun; Xiao-Ling Zhang; Zhen-Yuan Zhu; Chun-Yu Liu; Hui-Qing Sun; Xue-Qing Geng; Wei Jiang; Jia-He Wang (Natural Product Research, 2022)

Contrasting effects of plant-soil feedbacks on growth and morphology of physically-connected daughter and mother ramets in two clonal plants - Wei Xue; Lin Huang; Wei-Jia Sheng; Jia-Tao Zhu; Shu-Qi Li; Fei-Hai Yu (Plant and Soil, 2022)

Establishment of Galectin-3 Time-resolved Fluoroimmunoassay and its Application in Idiopathic Membranous Nephropathy - Xiaomei Yu; Lingli Chen; Bo Lin; Li Zhang; Xue Yang; Xiaobin Liu; Pengguo Xia; Yueming Liu; Shaoxiong Zheng; Xiumei Zhou; Yigang Wang; Yuan Qin; et al. (Journal of Fluorescence, 2022)

Projected change in precipitation forms in the Chinese Tianshan Mountains based on the Back Propagation Neural Network Model - Rui Ren; Xue-mei Li; Zhen Li; Lan-hai Li; Yi-yu Huang (Journal of Mountain Science, 2022)

Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae - Ying‐Ying Cai; Jing‐Yi Wang; Xi‐Yu Wu; Shuang Liang; Xue‐Ming Zhu; Lin Li; Jian‐Ping Lu; Xiao‐Hong Liu; Fu‐Cheng Lin (Environmental Microbiology, 2022)
Summary The development and pathogenicity of the fungus Magnaporthe oryzae , the causal agent of destructive rice blast disease, require it to perceive external environmental signals. Opy2, an overproduction‐induced pheromone‐resistant protein 2, is a crucial protein for sensing external signals in Saccharomyces cerevisiae . However, the biological functions of the homologue of Opy2 in M. oryzae are unclear. In this study, we identified that MoOPY2 is involved in fungal development, pathogenicity, and autophagy in M. oryzae . Deletion of MoOPY2 resulted in pleiotropic defects in hyphal growth, conidiation, germ tube extension, appressorium formation, appressorium turgor generation, and invasive growth, therefore leading to attenuated pathogenicity. Furthermore, MoOpy2 participates in the Osm1 MAPK pathway and the Mps1 MAPK pathway by interacting with the adaptor protein Mst50. The interaction sites of Mst50 and MoOpy2 colocalized with the autophagic marker protein MoAtg8 in the preautophagosomal structure sites (PAS). Notably, the Δ Moopy2 mutant caused cumulative MoAtg8 lipidation and rapid GFP‐MoAtg8 degradation in response to nitrogen starvation, showing that MoOpy2 is involved in the negative regulation of autophagy activity. Taken together, our study revealed that MoOpy2 of M. oryzae plays an essential role in the orchestration of fungal development, appressorium penetration, autophagy and pathogenesis.

Mutations in surface‐sensing receptor WspA lock the Wsp signal transduction system into a constitutively active state - Anming Xu; Di Wang; Yunhao Wang; Li Zhang; Zhensheng Xie; Yifan Cui; Pramod Bhamse; Haiying Yu; Xue‐Xian Zhang; Defeng Li; Luyan Z. Ma (Environmental Microbiology, 2022)
Summary Pseudomonas aeruginosa rugose small‐colony variants (RSCVs) are frequently isolated from chronic infections, yet, they are rarely reported in environmental isolates. Here, during the comparative genomic analysis of two P . aeruginosa strains isolated from crude oil, we discovered a spontaneous in‐frame deletion, wspA Δ280–307 , which led to hyper‐biofilm and RSCV phenotypes. WspA is a homologue of methyl‐accepting chemotaxis proteins (MCPs) that senses surfaces to regulate biofilm formation by stimulating cyclic‐di‐guanosine monophosphate (c‐di‐GMP) synthesis through the Wsp system. However, the methylation sites of WspA have never been identified. In this study, we identified E280 and E294 of WspA as methylation sites. The wspA Δ280–307 mutation enabled the Wsp system to lock into a constitutively active state that is independent of regulation by methylation. The result is an enhanced production of c‐di‐GMP. Sequence alignment revealed three conserved repeat sequences within the amino acid residues 280–313 (aa280–313) region of WspA homologues, suggesting that a spontaneous deletion within this DNA encoding region was likely a result of intragenic recombination and that similar mutations might occur in several related bacterial genera. Our results provide a plausible explanation for the selection of RSCVs and a mechanism to confer a competitive advantage for P . aeruginosa in a crude‐oil environment.

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Transcriptome Profiling Revealed Basis for Growth Heterosis in Hybrid Tilapia (Oreochromis niloticus ♀ × O. aureus ♂) - Jinglin Zhu; Zhiying Zou; Dayu Li; Wei Xiao; Jie Yu; Binglin Chen; Liangyi Xue; Hong Yang (Fishes, 2022)
Hybrid tilapia were produced from hybridization of Nile tilapia (Oreochromis niloticus) and blue tilapia (O. aureus). Comparative transcriptome analysis was carried out on the liver of hybrid tilapia and their parents by RNA sequencing. A total of 2319 differentially expressed genes (DEGs) were identified. Trend co-expression analysis showed that non-additive gene expression accounted for 67.1% of all DEGs. Gene Ontology and KEGG enrichment analyses classified the respective DEGs. Gene functional enrichment analysis indicated that most up-regulated genes, such as FASN, ACSL1, ACSL3, ACSL6, ACACA, ELOVL6, G6PD, ENO1, GATM, and ME3, were involved in metabolism, including fatty acid biosynthesis, unsaturated fatty acid biosynthesis, glycolysis, pentose phosphate pathway, amino acid metabolism, pyruvate metabolism, and the tricarboxylic acid cycle. The expression levels of a gene related to ribosomal biosynthesis in eukaryotes, GSH-Px, and those associated with heat shock proteins (HSPs), such as HSPA5 and HSP70, were significantly down-regulated compared with the parent tilapia lineages. The results revealed that the metabolic pathway in hybrid tilapia was up-regulated, with significantly improved fatty acid metabolism and carbon metabolism, whereas ribosome biosynthesis in eukaryotes and basal defense response were significantly down-regulated. These findings provide new insights into our understanding of growth heterosis in hybrid tilapia.

Functional Mechanism of Antimicrobial Peptide Bomidin and Its Safety for Macrobrachium rosenbergii - Miao Zhang; Youli Yu; Lele Lian; Wanjun Li; Jianluan Ren; Ying Liang; Feng Xue; Fang Tang; Xiaohua Zhu; Jianqun Ling; Jianjun Dai (Probiotics and Antimicrobial Proteins, 2022)

Comparative transcriptome analysis revealed the molecular mechanism of the effect of light intensity on the accumulation of rhynchophylline and isorhynchophylline in Uncaria rhynchophylla - Xiao-Hong Wang; Xue Li; Wei Qiang; Xiao-Song Yu; Hao-Jie Zheng; Ming-Sheng Zhang (Physiology and Molecular Biology of Plants, 2022)

Oxygen Metabolism-induced Stress Response Underlies Heart–brain Interaction Governing Human Consciousness-breaking and Attention - Xiao-Juan Xue; Rui Su; Ze-Feng Li; Xiao-Ou Bu; Peng Dang; Si-Fang Yu; Zhi-Xin Wang; Dong-Mei Chen; Tong-Ao Zeng; Ming Liu; Hai-Lin Ma; De-Long Zhang (Neuroscience Bulletin, 2022)

A 3D-QSAR model for the comprehensive bioenrichment and biodegradation effect of benzotriazole ultraviolet stabilisers and application of the model in molecular modification - Jiaqi Xue; Xinyi Chen; Qing Li; Ruihao Sun; Jiapeng Xiao; Yu Li (Environmental Science and Pollution Research, 2022)

Non-stop industries were the main source of air pollution during the 2020 coronavirus lockdown in the North China Plain - Zhen Li; Shaocai Yu; Mengying Li; Xue Chen; Yibo Zhang; Jiali Li; Yapping Jiang; Weiping Liu; Pengfei Li; Eric Lichtfouse (Environmental Chemistry Letters, 2022)

Differential functional connectivity of insular subdivisions in de novo Parkinson’s disease with mild cognitive impairment - Chenxi Pan; Jingru Ren; Lanting Li; Yuqian Li; Jianxia Xu; Chen Xue; Guanjie Hu; Miao Yu; Yong Chen; Li Zhang; Wenbing Zhang; Xiao Hu; et al. (Brain Imaging and Behavior, 2022)

Characterization of a novel Vibrio parahaemolyticus host-phage pair and antibacterial effect against the host - Chao Gao; Xiaobo Yang; Chen Zhao; Chenyu Li; Shang Wang; Xi Zhang; Bin Xue; Zhuosong Cao; Hongrui Zhou; Yutong Yang; Zhiqiang Shen; Pingfeng Yu; et al. (Archives of Virology, 2022)

New paraconic acids from the endophytic fungus Xylariaceae sp. J4 - Chao Yuan; Xue-Chun Shu; Lin Fan; Ying-Bo Zhang; Ling-Liang Guan; Fu-Lai Yu; Xiao-Lu Chen; Gang Li (Natural Product Research, 2022)

Mdivi-1 Modulates Macrophage/Microglial Polarization in Mice with EAE via the Inhibition of the TLR2/4-GSK3β-NF-κB Inflammatory Signaling Axis - Xiaoqin Liu; Xiaojuan Zhang; Xiaojie Niu; Peijun Zhang; Qing Wang; Xiuhua Xue; Guobin Song; Jiezhong Yu; Guoping Xi; Lijuan Song; Yanhua Li; Cungen Ma (Molecular Neurobiology, 2022)

Scalp Acupuncture Protects Against Neuronal Ferroptosis by Activating The p62-Keap1-Nrf2 Pathway in Rat Models of Intracranial Haemorrhage - Ming-Yue Li; Xiao-Hong Dai; Xue-Ping Yu; Wei Zou; Wei Teng; Peng Liu; Xin-Yang Yu; Qi An; Xin Wen (Journal of Molecular Neuroscience, 2022)
Intracerebral haemorrhage (ICH) can be a catastrophic event; even if the initial stages of the pathology were well-managed, a number of patients experience varied residual neurological deficits following the insult. Ferroptosis is a recently identified type of cell demise which is tightly linked to the neurological impairment associated with ICH. In the current work, the prophylactic impact of scalp acupuncture (SA) therapy on autologous blood injection murine models of ICH was investigated in order to establish whether SA could mitigate the secondary damage arising following ICH by moderating ferroptosis. The pathophysiological mechanisms associated with this process were also explored. Ludmila Belayev tests were utilised for the characterisation of neurological damage. Haematoxylin–eosin staining was employed in order to determine the cerebral impact of the induced ICH. Malondialdehyde (MDA) and iron titres in peri-haemorrhagic cerebral tissues were appraised using purchased assay kits. Transmission electron microscopy delineated mitochondrial appearances within nerve cell bodies from the area of haemorrhage. Western blotting techniques were utilised to assay the degree of protein expression of NeuN, sequestosome 1 (p62), nuclear factor erythroid 2-related factor 2 (Nrf2), Kelch-like ECH-associated protein 1 (Keap1), glutathione peroxidase 4 (GPX4) and ferritin heavy chain 1 (FTH1). The frequencies of Nrf2, GPX4 and FTH1 positive cells, respectively, were documented with immunohistochemical staining. The results demonstrated that therapy with SA after ICH mitigated MDA and iron sequestration, diminished the appearance of contracted mitochondria with increased outer mitochondrial membrane diameter within the nerve cell bodies, and suppressed neuronal ferroptosis. The pathways responsible for these effects may encompass amplified p62, Nrf2, GPX4 and FTH1 expression, together with decreased Keap1 expression. Application of SA reduced identified neurobehavioural abnormalities after ICH; no disparities were observed between the consequences of SA therapy and deferoxamine delivery. It can be surmised that intervention with SA enhanced recovery after ICH by triggering the antioxidant pathway, p62/Keap1/Nrf2, and causing FTH1 and GPX4 upregulation, factors that participate in diminishing excess iron and thus in mitigating lipid peroxidation insults arising from ferroptosis following ICH.

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

The Effects of Limosilactobacillus reuteri LR-99 Supplementation on Body Mass Index, Social Communication, Fine Motor Function, and Gut Microbiome Composition in Individuals with Prader–Willi Syndrome: a Randomized Double-Blinded Placebo-Controlled Trial - Xue-Jun Kong; Kevin Liu; Patrick Zhuang; Ruiyi Tian; Siyu Liu; Cullen Clairmont; Xiaojing Lin; Hannah Sherman; Junli Zhu; Yelan Wang; Michelle Fong; Alice Li; et al. (Probiotics and Antimicrobial Proteins, 2021)
Prader–Willi syndrome (PWS) is a rare genetic disorder associated with developmental delay, obesity, and neuropsychiatric comorbidities. Limosilactobacillus reuteri ( Lactobacillus reuteri , Lact. reuteri ) has demonstrated anti-obesity and anti-inflammatory effects in previous studies. In the present study, we aim to evaluate the effects of Lact. reuteri supplementation on body mass index (BMI), social behaviors, and gut microbiota in individuals with PWS. We conducted a 12-week, randomized, double-blind, placebo-controlled trial in 71 individuals with PWS aged 6 to 264 months (64.4 ± 51.0 months). Participants were randomly assigned to either receive daily Lact. reuteri LR-99 probiotic (6 × 10 10 colony forming units) or a placebo sachet. Groupwise differences were assessed for BMI, ASQ-3, and GARS-3 at baseline, 6 weeks, and 12 weeks into treatment. Gut microbiome data was analyzed with the QIIME2 software package, and predictive functional profiling was conducted with PICRUSt-2. We found a significant reduction in BMI for the probiotic group at both 6 weeks and 12 weeks relative to the baseline ( P < 0.05). Furthermore, we observed a significant improvement in social communication and interaction, fine motor function, and total ASQ-3 score in the probiotics group compared to the placebo group ( P < 0.05). Altered gut microbiota was observed in the probiotic group to favor weight loss and improve gut health. The findings suggest a novel therapeutic potential for Lact. reuteri LR-99 probiotic to modulate BMI, social behaviors, and gut microbiota in Prader–Willi syndrome patients, although further investigation is warranted. Trial registration Chinese Clinical Trial Registry: ChiCTR1900022646

Large scale control of surface ozone by relative humidity observed during warm seasons in China - Mengying Li; Shaocai Yu; Xue Chen; Zhen Li; Yibo Zhang; Liqiang Wang; Weiping Liu; Pengfei Li; Eric Lichtfouse; Daniel Rosenfeld; John H. Seinfeld (Environmental Chemistry Letters, 2021)

The time-dependent variations of zebrafish intestine and gill after polyethylene microplastics exposure - Ying-Hao Xue; Liang-Shan Feng; Zhi-Yu Xu; Feng-Yan Zhao; Xin-Li Wen; Tuo Jin; Zhan-Xiang Sun (Ecotoxicology, 2021)

In-Orbit Calibration Uncertainty of the Microwave Radiation Imager on board Fengyun-3C - Xinxin Xie; Wanting Meng; Jiakai He; Weimin Yu; Xue Li (Journal of Meteorological Research, 2021)

Long non-coding RNA TTC28-AS1 attenuates high glucose-induced damage in HK-2 cells depending on the regulation of miR-320a/CD2AP axis - Ji Zhang; Juan Ding; Ming Yu; Fang Li; Xue Zhou; Hongxia Shuai (Genes & Genomics, 2021)

Immersion immunization of common carp with bacterial ghost‐based DNA vaccine inducing prophylactic protective immunity against spring viraemia of carp virus - Yu‐Ying Zheng; Chen Zhang; Yang Li; Peng‐Qi Zhang; Guo Chen; Gao‐Xue Wang; Bin Zhu (Journal of Fish Diseases, 2021)
The interactive applications of immunization route, vaccine type and delivery vectors are emerging as a key area of research within the field of mass immunization in fishery production. In an effort to improve DNA vaccine's immune efficiency in large‐scale immunization, a promising bacterial ghost‐loaded DNA vaccine was constructed based on Escherichia coli DH5α. In common carp was investigated the immune response to immersion immunization via related indicator analysis, and the challenge test of spring viraemia of carp virus (SVCV) was carried out. The result indicated that BG‐loaded DNA vaccine induced higher serum antibody level than naked pEG‐G. Simultaneously, the immunophysiological indicators and genes change at the more advanced levels in the BG/pEG‐G immune group. At the treatment concentration of 20 mg/L of the BG/pEG‐G group, IgM and IgZ expressions in vivo were markedly increased by 21.62 times and 6.91 times, respectively, and the relative percentage survival reached the peak of 59.57%. This study paves the way for future aquatic animal vaccine research, which aimed to develop the highly effective immersion vaccine system by delivery vectors, with the ultimate aim to prevent and restrict SVCV in actual production.

Optimization of immunization procedure for SWCNTs‐based subunit vaccine with mannose modification against spring viraemia of carp virus in common carp - Yu‐Ming Gong; Chen Zhang; Yang Li; Guo Chen; Gao‐Xue Wang; Bin Zhu (Journal of Fish Diseases, 2021)
Immersion vaccination of single‐walled carbon nanotubes loaded with mannose‐modified glycoprotein (SWCNTs‐MG) vaccine has been proved to be effective in preventing spring viraemia of carp virus (SVCV). Immunization procedure has immense consequence on the immune effect of the immersion vaccine. However, immunization procedure optimization for SWCNTs‐MG vaccine against SVCV has not been reported. In this study, accordingly, a full‐factor experiment was designed to optimize the immunization procedure of SWCNTs‐MG vaccine by three aspects of vaccine dose (30 mg/L, 40 mg/L and 50 mg/L), immunization density (8 fish L −1 , 24 fish L −1 and 48 fish L −1 ) and immunization time (6, 12 and 24 hr). Furthermore, we used the immunization group (A1B2C1, 30 mg/L, 24 fish L −1 and 6 hr) in the previous study as a positive control (PC) to evaluate the immunization effect optimized conditions from the expression of immune‐related genes and relative percentage survival (RPS). At 28 days post‐vaccination (DPV), common carps were intraperitoneal injected SVCV challenged test indicated that the A1B2C2 group (30 mg/L, 24 fish L −1 , 12 hr) displayed superiority of protective efficacy compare with other groups and the RPS with 77.9%, which was 15.6% higher than the PC group of RPS with 62.3%. Moreover, the expression of immune‐related genes such as IL‐10 , CD4 and MHC‐II was also significantly higher than PC group. The specific experimental flow chart is shown in Figure 1 . Conclusively, these results demonstrated that vaccine dose, immunization density and immunization time are 30 mg/L, 24 fish L −1 and 12 hr, which is the more appropriate immunization programme with juvenile carp for SWCNTs‐MG vaccine. This study provides a profitable reference for improving the immune efficiency of aquatic immersion vaccine. The experiment process and timeline chart of the present research image

Progress in the pretreatment and analysis of N-nitrosamines: an update since 2010 - Yu Bian; Yuan Zhang; Yu Zhou; Guo-hui Li; Xue-song Feng (Critical Reviews in Food Science and Nutrition, 2021)

Three new diterpenoids from Euphorbia peplus - Yan-Ni Chen; Qing-Yun Lu; Dong-Mei Li; Ying-Yao Li; Xue-Xue Pu; Bo-Ting Li; Xiao-Han Tang; Hong-Yu Tang; Shuai Liu; Lei Yang; Yu Zhang; Ying-Tong Di; et al. (Natural Product Research, 2021)

Constitutive expression of two A-5 subgroup DREB transcription factors from desert shrub Ammopiptanthus mongolicus confers different stress tolerances in transgenic Arabidopsis - Xuefeng Wang; Li Ma; Huiling Zhang; Yu Zhang; Min Xue; Meiyan Ren; Kuangang Tang; Huiqin Guo; Maoyan Wang (Plant Cell, Tissue and Organ Culture (PCTOC), 2021)

Impact of rhizosphere microorganisms on arsenic (As) transformation and accumulation in a traditional Chinese medical plant - Jiao-Jiao Li; Long Yang; Cui-Ping Miao; Ya-Jun Teng; Zi-Hao Fu; Chang-Lei Cheng; Xue-Xiu Chang; Yu Qian; Li-Xing Zhao (Environmental Science and Pollution Research, 2021)

Composition analysis of PM2.5 at multiple sites in Zhengzhou, China: implications for characterization and source apportionment at different pollution levels - Xiaohan Liu; Nan Jiang; Ruiqin Zhang; Xue Yu; Shengli Li; Qingqing Miao (Environmental Science and Pollution Research, 2021)

Effects of organic acids on the chemotaxis profiles and biocontrol traits of antagonistic bacterial endophytes against root-rot disease in Panax notoginseng - Li Ma; Wu-Qin Wang; Rui Shi; Xue-Mei Zhang; Xin Li; Yu-Sen Yang; Ming He Mo (Antonie van Leeuwenhoek, 2021)

Seasonal progression of photoprotection responses in different aged savin juniper plants under shade and sun - Jin-Ling Zhang; Xiao-Gang Li; Xue-Hua Xu; Hai-Peng Chen; Yu-Ling Li; Robert D. Guy (Trees, 2021)

Atorvastatin Pretreatment Ameliorates Mesenchymal Stem Cell Migration through miR-146a/CXCR4 Signaling - Na Li; Xue-Yuan Guo; Jian Zhou; Xian-Liang Yan; Fang-Fang Yu (Tissue Engineering and Regenerative Medicine, 2021)

Genetic and molecular characterization of determinant of six-rowed spike of barley carrying vrs1.a4 - Jin-Hui Wang; Zhen-Mei Xu; Xue-Bing Qiu; Li-Lan Li; Shui-Yang Yu; Tao Li; Yan-Yan Tang; Xi Pu; Juan-Yu Zhang; Hai-Li Zhang; Jun-Jun Liang; Ya-Wei Tang; et al. (Theoretical and Applied Genetics, 2021)

Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice - Lin Chen; Shu-Yu Ren; Rui-Xue Li; Kun Liu; Jing-Fei Chen; Yu-Jian Yang; Yong-Bin Deng; Han-Zhi Wang; Lan Xiao; Feng Mei; Fei Wang (Neuroscience Bulletin, 2021)
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths ( NG2-CreER TM ; Tau-mGFP ), we found that myelinogenesis was highly active in most brain regions, such as the motor cortex and corpus callosum. After exposure to hypoxia (10% oxygen) 12 h per day for 4 weeks, myelinogenesis was largely inhibited in the 4-month old brain and the mice displayed motor coordination deficits revealed by the beam-walking test. To determine the relationship between the inhibited myelination and functional impairment, we induced oligodendroglia-specific deletion of the transcription factor Olig2 by tamoxifen ( NG2-CreER TM ; Tau-mGFP; Olig2 fl/fl ) in adult mice to mimic the decreased myelinogenesis caused by hypoxia. The deletion of Olig2 inhibited myelinogenesis and consequently impaired motor coordination, suggesting that myelinogenesis is required for motor function in adult mice. To understand whether enhancing myelination could protect brain functions against hypoxia, we treated hypoxic mice with the myelination-enhancing drug-clemastine, which resulted in enhanced myelogenesis and improved motor coordination. Taken together, our data indicate that chronic hypoxia inhibits myelinogenesis and causes functional deficits in the brain and that enhancing myelinogenesis protects brain functions against hypoxia-related deficits.

Emerging role of air pollution in chronic kidney disease - Yue Chen; Fan Cao; Jian-Ping Xiao; Xin-Yu Fang; Xue-Rong Wang; Li-Hong Ding; De-Guang Wang; Hai-Feng Pan (Environmental Science and Pollution Research, 2021)

Do foreign direct investment and environmental regulation improve green technology innovation? An empirical analysis based on panel data from the Chinese manufacturing industry - Shi-Chun Xu; Yun-Fan Li; Jing-Nan Zhang; Yan Wang; Xiao-Xue Ma; Hong-Yu Liu; Hai-Ning Wang; Yuan Tao (Environmental Science and Pollution Research, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia - Jing Guo; Xiao-Li-Na Zhang; Zhang-Rui Bao; Xue-Ke Yang; Ling-Shuang Li; Yu Zi; Fan Li; Chun-Yun Wu; Juan-Juan Li; Yun Yuan (NeuroMolecular Medicine, 2021)

Effect of fasting on protein metabolism in muscle tissue of Larimichthys crocea revealed by transcriptome and proteome - Yu Zhang; Weiliang Shen; Juan Li; Baoxiao Zheng; Zhengjia Lou; Mohammad Aslam Hosain; Baoying Qian; Liangyi Xue (Journal of Oceanology and Limnology, 2021)

Transcriptome analysis of flower color variation in five Rhododendron species (Ericaceae) - Zhiliang Li; Qiaofeng Yang; Xue Dong; Yu Zhu; Shuang Zhao; Wenying Zhang; Shuzhen Wang (Brazilian Journal of Botany, 2021)

Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination - Kun Liu; Bin Yu; Jing-Fei Chen; Rui-Xue Li; Lin Chen; Shu-Yu Ren; Fei Wang; Feng Mei; Lan Xiao (Neuroscience Bulletin, 2021)
Increasing evidence has shown that astrocytes are implicated in regulating oligodendrocyte myelination, but the underlying mechanisms remain largely unknown. To understand whether microRNAs in astrocytes function in regulating oligodendroglial differentiation and myelination in the developing and adult CNS, we generated inducible astrocyte-specific Dicer conditional knockout mice (hGFAP-CreERT; Dicer fl/fl). By using a reporter mouse line (mT/mG), we confirmed that hGFAP-CreERT drives an efficient and astrocyte-specific recombination in the developing CNS, upon tamoxifen treatment from postnatal day 3 (P3) to P7. The Dicer deletion in astrocytes resulted in inhibited oligodendroglial differentiation and myelination in the developing CNS of Dicer cKO mice at P10 and P14, and did not alter the densities of neurons or axons, indicating that Dicer in astrocytes is required for oligodendrocyte myelination. Consequently, the Dicer deletion in astrocytes at P3 resulted in impaired spatial memory and motor coordination at the age of 9 weeks. To understand whether Dicer in astrocytes is also required for remyelination, we induced Dicer deletion in 3-month-old mice and then injected lysolecithin into the corpus callosum to induce demyelination. The Dicer deletion in astrocytes blocked remyelination in the corpus callosum 14 days after induced demyelination. Together, our results indicate that Dicer in astrocytes is required for oligodendroglia myelination in both the developing and adult CNS.

Establishment and characterization of the Bactrocera dorsalis (Diptera: Tephritidae) embryonic cell line QAU-Bd-E-2 - Gui-Ling Zheng; Jie Li; Qian-Long Yu; Bin Zhang; Xue-Meng Ding; Hui Li; Hong-Xu Zhou; Fang-Hao Wan; Chang-You Li (In Vitro Cellular & Developmental Biology - Animal, 2021)

Stepwise selection of mutation conferring fluroquinolone resistance: multisite MDR-TB cohort study - Jingtao Gao; Jian Du; Wei Shu; Yuhong Liu; Yufeng Wang; Zhongtan Xue; Liang Li; Yu Pang (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

OSL chronology of a Palaeolithic site in a humid subtropical mountainous area of southeast China - Jian-hui Jin; Xiao-yang Wang; Zhen-yu Zhou; Yun-ming Huang; Xue-chun Fan; Xin-xin Zuo; Zhi-zhong Li; Zhi-yong Ling; Yong-qing Ren; Shu-tong Li (Journal of Mountain Science, 2021)

Comparison of the Digestion and Absorption Characteristics of Docosahexaenoic Acid-Acylated Astaxanthin Monoester and Diester in Mice - Ye Li; Jie Yu; Jie Xu; Hongxia Che; Yuming Wang; Changhu Xue; Qingrong Huang; Tiantian Zhang (Journal of Ocean University of China, 2021)

Sum of High-Risk Gene Mutation (SHGM): A Novel Attempt to Assist Differential Diagnosis for Adrenocortical Carcinoma with Benign Adenoma, Based on Detection of Mutations of Nine Target Genes - Guo-Yang Zheng; Xue-Bin Zhang; Han-Zhong Li; Yu-Shi Zhang; Jian-Hua Deng; Xing-Cheng Wu (Biochemical Genetics, 2021)
There has been no research on applying gene detection to differential diagnosis of adrenocortical carcinoma (ACC). We attempted to explore a novel auxiliary method for differential diagnosis between ACC with benign adrenocortical adenoma (ACA), based on mutations of target genes in tissues. Nine genes were chosen as target genes, including TP53, CTNNB1, ARMC5, PRKAR1A, ZNRF3, RB1, APC, MEN1, and RPL22 . Exons sequencing of target genes were performed in 98 cases of tissue samples by FastTarget technology, including 41 ACC tissues, 32 ACA tissues, and 25 normal adrenal gland tissues. Significant mutations were detected and identified, and the clinical information was collected, for further comparative analysis and application to assist differential diagnosis of ACC. We identified 132 significant gene mutations and 227 significant mutation sites in 37 ACC tissues, much more than ACA and normal adrenal gland tissues. Mutation rates of 6 genes in ACC tissues were obviously higher than ACA tissues, including ZNRF3, ARMC5, TP53, APC, RB1, and PRKAR1A , regarded as high-risk genes. The sum of mutated high-risk genes detected in each sample was denominated sum of high-risk gene mutation (SHGM), and the rates of SHGM > 0 and SHGM > 1 in ACC tissues were 73.0% and 62.2%, respectively, both obviously higher than those in ACA tissues, with significant statistic differences. Especially for 8 cases of ACC with diameter 0 and SHGM > 1 were found in 6 samples (75%) and 4 samples (50%), respectively. However, no relevance was found between SHGM and clinical characteristics of ACC. We identified 6 high-risk genes in ACC tissues, with significantly higher mutation rates than ACA or normal adrenal gland tissues. The sum of mutated high-risk genes detected in ACC tissues was denominated SHGM, which was potential to assist the differential diagnosis of ACC with ACA, especially for the small-size ACC.

Caulobacter endophyticus sp. nov., an endophytic bacterium harboring three lasso peptide biosynthetic gene clusters and producing indoleacetic acid isolated from maize root - Jun-lian Gao; Pengbo Sun; Yu-chen Sun; Jing Xue; Guoliang Wang; Li-wei Wang; Yunpeng Du; Xiuhai Zhang; Jian-guang Sun (Antonie van Leeuwenhoek, 2021)

Maritime Broadband Communication: Wireless Channel Measurement and Characteristic Analysis for Offshore Waters - Changzhen Li; Junyi Yu; Jie Xue; Wei Chen; Shoufeng Wang; Kun Yang (Journal of Marine Science and Engineering, 2021)
For a long time, the development of maritime communication has been restricted by the low data rate, high-latency and high cost of the current communication systems. The upgrade of new generation mobile communication technologies is attracting more and more attention to conduct a shore-based broadband mobile communication network with high-latency and high reliability to serve the maritime industries. This paper presents a solution by means of building a ship-to-infrastructure (S2I) and a ship-to-ship (S2S) wireless communication networks for an offshore region. We characterize the S2I and S2S channels at 5.9 GHz band based on the channel measurements in realistic environments. The channel characteristics, including power delay profile, delay spread, propagation path loss, are extracted and analyzed. In view of the difference between marine and terrestrial communications, we analyze the influencing factors of the offshore water, including effective reflection, divergence and shadowing from the water surface, and diffraction loss caused by the earth curvature. We also predict the power coverage range and the channel capacity for S2I and S2S wireless communications. Finally, the communication performance is evaluated according to the channel measurement and characterization analysis. The research results can be a reference for the construction of maritime communication networks.

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

Long Non-coding RNA GAS5 Worsens Coronary Atherosclerosis Through MicroRNA-194-3p/TXNIP Axis - Yanbing Li; Yu Geng; Boda Zhou; Xuejiao Wu; Ou Zhang; Xiaonan Guan; Yajun Xue; Siyuan Li; Xianjing Zhuang; Jie Zhou; Meng Chang; Guobin Miao; et al. (Molecular Neurobiology, 2021)
It is formerly conducted that long non-coding RNA growth arrest-specific 5 (GAS5) is involved in the process of coronary atherosclerosis (AS). The regulatory effects of GAS5 on the microRNA (miR)-194-3p/thioredoxin-interacting protein (TXNIP) axis in AS have been insufficiently explored yet. Thereafter, this work is started from GAS5/miR-194-3p/TXNIP axis in AS. AS rats were modeled to obtain their coronary vascular tissues and endothelial cells (ECs), in which GAS5, miR-194-3p, and TXNIP expression were tested. ECs were identified by immunohistochemistry. The mechanism among GAS5, miR-194-3p, and TXNIP was determined. ECs were transfected with inhibited GAS5 or overexpressed miR-194-3p to decipher their functions in proliferation and apoptosis of ECs in AS. Raised GAS5 and TXNIP and degraded miR-194-3p expression levels exhibited in AS. GAS5 bound to miR-194-3p while miR-194-3p targeted TXNIP. Depleting GAS5 or restoring miR-194-3p enhanced proliferation and depressed apoptosis of ECs in AS. This work clearly manifests that inhibited GAS5 facilitates the growth of ECs through miR-194-3p-targeted TXNIP in AS, consolidating the basal reference to the curing for AS.

Reference Electrode Standardization Interpolation Technique (RESIT): A Novel Interpolation Method for Scalp EEG - Li Dong; Lingling Zhao; Yufan Zhang; Xue Yu; Fali Li; Jianfu Li; Yongxiu Lai; Tiejun Liu; Dezhong Yao (Brain Topography, 2021)
“Bad channels” are common phenomena during scalp electroencephalography (EEG) recording that arise due to various technique-related reasons, and reconstructing signals from bad channels is an inevitable choice in EEG processing. However, current interpolation methods are all based on purely mathematical interpolation theory, ignoring the neurophysiological basis of the EEG signals, and their performance needs to be further improved, especially when there are many scattered or adjacent bad channels. Therefore, a new interpolation method, named the reference electrode standardization interpolation technique (RESIT), was developed for interpolating scalp EEG channels. Resting-state and event-related EEG datasets were used to investigate the performance of the RESIT. The main results showed that (1) assuming 10% bad channels, RESIT can reconstruct the bad channels well; (2) as the percentage of bad channels increased (from 2% to 85%), the absolute and relative errors between the true and RESIT-reconstructed signals generally increased, and the correlations between the true and RESIT signals decreased; (3) for a range of bad channel percentages (2% ~ 85%), the RESIT had lower absolute error (approximately 2.39% ~ 33.5% reduction), lower relative errors (approximately 1.3% ~ 35.7% reduction) and higher correlations (approximately 2% ~ 690% increase) than traditional interpolation methods, including neighbor interpolation (NI) and spherical spline interpolation (SSI). In addition, the RESIT was integrated into the EEG preprocessing pipeline on the WeBrain cloud platform ( https://webrain.uestc.edu.cn/ ). These results suggest that the RESIT is a promising interpolation method for both separate and simultaneous EEG preprocessing that benefits further EEG analysis, including event-related potential (ERP) analysis, EEG network analysis, and strict group-level statistics.

Roles of bulk and rhizosphere denitrifying bacteria in denitrification from paddy soils under straw return condition - Ning Wang; Ya-Hui Zhao; Jian-Guang Yu; Li-Hong Xue; Hong-Bo Li; Lin-Zhang Yang (Journal of Soils and Sediments, 2021)

Five matrine-type alkaloids from Sophora tonkinensis - Qing Tang; Ding Luo; Ding-Chai Lin; Wen-Zhi Wang; Can-Jie Li; Xue-Fang Zhuo; Zhong-Nan Wu; Yu-Bo Zhang; Guo-Cai Wang; Yao-Lan Li (Journal of Natural Medicines, 2021)

Design of supercontinuum laser hyperspectral light detection and ranging (LiDAR) (SCLaHS LiDAR) - Guoqing Zhou; Xiang Zhou; Youjian Song; Donghui Xie; Long Wang; Guangjian Yan; Minglie Hu; Bowen Liu; Weidong Shang; Chenghu Gong; Cheng Wang; Huaguo Huang; et al. (International Journal of Remote Sensing, 2021)

Seasonal Variations in Total Lipid and Fatty Acid Composition of Haliotis discus Hannai from Three Different Production Zones - Lipin Chen; Qi Wang; Xiaohan Cong; Fanqianhui Yu; Yong Xue; Qingjuan Tang; Changhu Xue; Yanqing Liu; Zhaojie Li (Journal of Aquatic Food Product Technology, 2021)

Biotransformation of Phlorizin by Eurotium cristatum to Increase the Antioxidant and Antibacterial Activity of Docynia indica Leaves - Jie Xie; Jiang Chen; Xue-ran Mei; Ming-jun Zhu; Xue-li Li; Juan Du; Xiao-yu Zhang (Current Microbiology, 2021)

The changes of brain functional networks in young adult smokers based on independent component analysis - XianFu Wang; Ting Xue; Fang Dong; Yangding Li; Dongdong Xie; Chang Liu; Ming Zhang; Yanzhi Bi; Kai Yuan; Dahua Yu (Brain Imaging and Behavior, 2021)

Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation - Xiaoli Liu; Yan Gu; Yaoyao Bian; Danhong Cai; Yu Li; Ye Zhao; Zhaofeng Zhang; Mei Xue; Liang Zhang (Apoptosis, 2021)
Acute promyelocytic leukemia (APL) is a blood system disease caused by the accumulation of a large number of immature blood cells in bone marrow. Although the introduction of all- trans retinoic acid (ATRA) and arsenic has reached a high level of complete remission rate and 5-year disease-free survival rate, the occurrence of various adverse reactions still severely affects the quality of life of patients. As a natural product, honokiol (HNK) has the advantages of low toxicity and high efficiency, and it is a potential drug for the treatment of cancer. Since cancer cells can escape apoptotic cell death through multiple adaptive mechanisms, HNK, a drug that induces cancer cell death in a nonapoptotic way, has attracted much interest. We found that HNK reduced the viability of human APL cell line (NB4 cells) by inducing paraptosis-like cell death. The process was accompanied by excessive reactive oxygen species (ROS), mitochondrial damage, endoplasmic reticulum stress, and increased microtubule-associated protein 1 light chain 3 (LC3) processing. The inactivation of proteasome activity was the main cause of misfolded and unfolded protein accumulation in endoplasmic reticulum, such as LC3II/I and p62. This phenomenon could be alleviated by adding cycloheximide (CHX), a protein synthesis inhibitor. We found that mTOR signaling pathway participated in paraptosis-like cell death induced by HNK in an autophagy-independent process. Moreover, the mitogen-activated protein kinase (MAPK) signaling pathway induced paraptosis of NB4 cells by promoting endoplasmic reticulum stress. In summary, these findings indicate that paraptosis may be a new way to treat APL, and provide novel insights into the potential mechanism of paraptosis-like cell death.

EmhR is an indole‐sensing transcriptional regulator responsible for the indole‐induced antibiotic tolerance in Pseudomonas fluorescens - Jian‐Ting Han; Di‐Yin Li; Meng‐Yuan Zhang; Xiao‐Quan Yu; Xiang‐Xue Jia; Hang Xu; Xu Yan; Wen‐Juan Jia; Shaomin Niu; Megan L. Kempher; Xuanyu Tao; Yong‐Xing He (Environmental Microbiology, 2021)
Summary Indole is well known as an interspecies signalling molecule to modulate bacterial physiology; however, it is not clear how the indole signal is perceived and responded to by plant growth promoting rhizobacteria (PGPR) in the rhizosphere. Here, we demonstrated that indole enhanced the antibiotic tolerance of Pseudomonas fluorescens 2P24, a PGPR well known for its biocontrol capacity. Proteomic analysis revealed that indole influenced the expression of multiple genes including the emhABC operon encoding a major multidrug efflux pump. The expression of emhABC was regulated by a TetR‐family transcription factor EmhR, which was demonstrated to be an indole‐responsive regulator. Molecular dynamics simulation showed that indole allosterically affected the distance between the two DNA‐recognizing helices within the EmhR dimer, leading to diminished EmhR–DNA interaction. It was further revealed the EmhR ortholog in Pseudomonas syringae was also responsible for indole‐induced antibiotic tolerance, suggesting this EmhR‐dependent, indole‐induced antibiotic tolerance is likely to be conserved among Pseudomonas species. Taken together, our results elucidated the molecular mechanism of indole‐induced antibiotic tolerance in Pseudomonas species and had important implications on how rhizobacteria sense and respond to indole in the rhizosphere.

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

Wolbachia and Spiroplasma could influence bacterial communities of the spider mite Tetranychus truncatus - Kun Yang; Han Chen; Xiao-Li Bing; Xue Xia; Yu-Xi Zhu; Xiao-Yue Hong (Experimental and Applied Acarology, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

An ultrahigh‐throughput screening platform based on flow cytometric droplet sorting for mining novel enzymes from metagenomic libraries - Fuqiang Ma; Tianjie Guo; Yifan Zhang; Xue Bai; Changlong Li; Zelin Lu; Xi Deng; Daixi Li; Katsuo Kurabayashi; Guang‐yu Yang (Environmental Microbiology, 2021)
Summary Uncultivable microbial communities provide enormous reservoirs of enzymes, but their experimental identification by functional metagenomics is challenging, mainly due to the difficulty of screening enormous metagenomic libraries. Here, we propose a reliable and convenient ultrahigh‐throughput screening platform based on flow cytometric droplet sorting (FCDS). The FCDS platform employs water‐in‐oil‐in‐water double emulsion droplets serving as single‐cell enzymatic micro‐reactors and a commercially available flow cytometer, and it can efficiently isolate novel biocatalysts from metagenomic libraries by processing single cells as many as 10 8 per day. We demonstrated the power of this platform by screening a metagenomic library constructed from domestic running water samples. The FCDS assay screened 30 million micro‐reactors in only 1 h, yielding a collection of esterase genes. Among these positive hits, Est WY was identified as a novel esterase with high catalytic efficiency and distinct evolutionary origin from other lipolytic enzymes. Our study manifests that the FCDS platform is a robust tool for functional metagenomics, with the potential to significantly improve the efficiency of exploring novel enzymes from nature.

Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human - Ya-Xin Fan; Yuan-Cheng Chen; Yi Li; Ji-Cheng Yu; Xing-Chen Bian; Xin Li; Wan-Zhen Li; Bei-Ning Guo; Hai-Lan Wu; Xiao-Fen Liu; Yu Wang; Xiao-Yong Xu; et al. (Pharmaceutical Research, 2021)

A plant virus mediates interspecific competition between its insect vectors in Capsicuum annuum - Yong Chen; Xue Zheng; Hui Wei; Yong-Dui Chen; Kuan-Yu Zheng; Ye Mu; Xing-Yue Zhao; Li-Hua Zhao; Yu-Lin Gao; Li-Min Zheng; Jie Zhang (Journal of Pest Science, 2021)

A Novel Fluorescent Probe Based on Pyrazole-Pyrazoline for Fe (III) Ions Recognition - Ying-Peng Zhang; Xiang-Fang Li; Yun-Shang Yang; Jing-Li Wang; Yu-Chen Zhao; Ji-Jun Xue (Journal of Fluorescence, 2021)

Paenibacillus turpanensis sp. nov., isolated from a salt lake of Turpan city in Xinjiang province, north-west China - Li Yang; Hua-Wei Huang; Yun Wang; Ya-Rong Kou; Min Yin; Yu Li; Xue-Qian Wang; Gui-Fang Zhao; Wen-Yong Zhu; Shu-Kun Tang (Archives of Microbiology, 2021)

Three-dimensional numerical modeling of water distribution tunnels in karst area - Xiao-dong Pan; Yu-chao Fang; Yong Lai; Hong-lei Sun; Yuan-qiang Cai; Li Shi; Xue-yu Geng (Arabian Journal of Geosciences, 2020)

Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions - Xiuxiu Li; Zhuo Chen; Guomin Zhang; Hongwei Lu; Peng Qin; Ming Qi; Ying Yu; Bingke Jiao; Xianfeng Zhao; Qiang Gao; Hao Wang; Yunyu Wu; et al. (Science China Life Sciences, 2020)

The Microscopic Mechanism of Crack Evolution in Brittle Material Containing 3-D Embedded Flaw - Bangxiang Li; Song Yu; Weishen Zhu; Weibing Cai; Lei Yang; Yiguo Xue; Yong Li (Rock Mechanics and Rock Engineering, 2020)

Synthesis and molecular docking studies of novel pyrimidine derivatives as potential antibacterial agents - Xue-Qian Bai; Chun-Shi Li; Ming-Yue Cui; Ze-Wen Song; Xing-Yu Zhou; Chao Zhang; Yang Zhao; Tian-Yi Zhang; Tie-Yan Jiang (Molecular Diversity, 2020)

Characteristics of methane emissions in the Living Water Garden in Chengdu City from 2012 to 2017 - Ru Xue; Xiaoling Liu; Xiaoying Fu; Hongbing Luo; Ke Zhang; Bruce C. Anderson; Mei Li; Bo Huang; Lijuan Yu; Xiaoting Li; Shuzhi Fu; Aiping Pu; et al. (Environmental Science and Pollution Research, 2020)

Erratum to: An Examination of the Predictability of Tropical Cyclone Genesis in High-Resolution Coupled Models with Dynamically Downscaled Coupled Data Assimilation Initialization - Mingkui Li; Shaoqing Zhang; Lixin Wu; Xiaopei Lin; Ping Chang; Gohkan Danabasoglu; Zhiqiang Wei; Xiaolin Yu; Huiqin Hu; Xiaohui Ma; Weiwei Ma; Haoran Zhao; et al. (Advances in Atmospheric Sciences, 2020)

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway - Jia-Ru Wang; Tian-Zhu Li; Cheng Wang; Shu-Mei Li; Ying-Hua Luo; Xian-Ji Piao; Yu-Chao Feng; Yi Zhang; Wan-Ting Xu; Yu Zhang; Tong Zhang; Shi-Nong Wang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Highly sensitive serological approaches for Pepino mosaic virus detection - Wan-qin He; Jia-yu Wu; Yi-yi Ren; Xue-ping Zhou; Song-bai Zhang; Ya-juan Qian; Fang-fang Li; Jian-xiang Wu (Journal of Zhejiang University-SCIENCE B, 2020)

Psychroflexus maritimus sp. nov., isolated from coastal sediment - Yan-Lin Zhong; Rui Zhang; Xiao-Yu Zhang; Li-Xue Yu; Meng-Fan Zhao; Zong-Jun Du (Archives of Microbiology, 2020)

Numerical Simulation of a Polar Ship Moving in Level Ice Based on a One-Way Coupling Method - Bao-Yu Ni; Zi-Wang Chen; Kai Zhong; Xin-Ang Li; Yan-Zhuo Xue (Journal of Marine Science and Engineering, 2020)
In most previous ice–ship interaction studies involving fluid effects, ice was taken as unbreakable. Building breakable level ice on water domain is still a big challenge in numerical simulation. This paper overcomes this difficulty and presents a numerical modeling of a ship moving in level ice on the water by using a one-way CFD-DEM (computational fluid dynamics-discrete element method) coupling method. The detailed numerical processes and techniques are introduced. The ice crack propagation process including radial and circular cracks have been observed. Numerical results are compared with previous experimental data and good agreement has been achieved. The results show that water resistance is an order of magnitude smaller than ice resistance during the ice-breaking process. Ice resistance shows strong oscillation along with ice failure process, which are affected by ship speed and ice thickness significantly.

Associations of egg consumption with incident cardiovascular disease and all-cause mortality - Xue Xia; Fangchao Liu; Xueli Yang; Jianxin Li; Jichun Chen; Xiaoqing Liu; Jie Cao; Chong Shen; Ling Yu; Yingxin Zhao; Xianping Wu; Liancheng Zhao; et al. (Science China Life Sciences, 2020)

Interplay between hydrogen sulfide and methylglyoxal initiates thermotolerance in maize seedlings by modulating reactive oxidative species and osmolyte metabolism - Xin-Yu Ye; Xue-Mei Qiu; Yu-Ying Sun; Zhong-Guang Li (Protoplasma, 2020)

A novel function of IRF9 in acute pancreatitis by modulating cell apoptosis, proliferation, migration, and suppressing SIRT1-p53 - Bin-Hua Xue; Yi Liu; Hu Chen; Yun Sun; Wei-Li Yu (Molecular and Cellular Biochemistry, 2020)

Unexpected rise of ozone in urban and rural areas, and sulfur dioxide in rural areas during the coronavirus city lockdown in Hangzhou, China: implications for air quality - Liqiang Wang; Mengying Li; Shaocai Yu; Xue Chen; Zhen Li; Yibo Zhang; Linhui Jiang; Yan Xia; Jiali Li; Weiping Liu; Pengfei Li; Eric Lichtfouse; et al. (Environmental Chemistry Letters, 2020)

Identification and genome characterization of a novel picornavirus from ducks in China - Yufeng Li; Kaicheng Wang; Kexiang Yu; Feng Hu; Xue Tian; Bing Huang; Hualei Liu; Jiaqiang Wu; Minxun Song (Archives of Virology, 2020)

An Examination of the Predictability of Tropical Cyclone Genesis in High-Resolution Coupled Models with Dynamically Downscaled Coupled Data Assimilation Initialization - Mingkui Li; Shaoqing Zhang; Lixin Wu; Xiaopei Lin; Ping Chang; Gohkan Danabasoglu; Zhiqiang Wei; Xiaolin Yu; Huiqin Hu; Xiaohui Ma; Weiwei Ma; Haoran Zhao; et al. (Advances in Atmospheric Sciences, 2020)

Geochemical Characteristics and Hydrocarbon Expulsion of Lacustrine Marlstones in the Shulu Sag, Bohai Bay Basin, Eastern China: Assessment of Tight Oil Resources - Zhipeng Huo; Xuan Tang; Qingkuan Meng; Jinchuan Zhang; Changrong Li; Xiaofei Yu; Xue Yang (Natural Resources Research, 2020)

Gill transcriptomes reveal expression changes of genes related with immune and ion transport under salinity stress in silvery pomfret (Pampus argenteus) - Juan Li; Liangyi Xue; Mingyue Cao; Yu Zhang; Yajun Wang; Shanliang Xu; Baoxiao Zheng; Zhengjia Lou (Fish Physiology and Biochemistry, 2020)

Effects of an oasis protective system on aeolian sediment deposition: a case study from Gelintan oasis, southeastern edge of the Tengger Desert, China - Jing Ding; Yun-hu Xie; Xiao-jia Li; Hong-tao Jiang; Ji Wang; Xiao-xi Liu; Xue-qin Wu; Yu-hao Wang; Chun-xing Hai (Journal of Mountain Science, 2020)

Lysinibacillus cavernae sp. nov., isolated from cave soil - Yu Kan; Xue-Ke Niu; Manik Prabhu Narsing Rao; Zhou-Yan Dong; Yuan-Guo Xie; Ying-Qian Kang; Wen-Jun Li (Archives of Microbiology, 2020)

Mesorhizobium rhizophilum sp. nov., a 1-aminocyclopropane-1-carboxylate deaminase producing bacterium isolated from rhizosphere of maize in Northeast China - Jun-lian Gao; Jing Xue; Yu-chen Sun; Han Xue; En Tao Wang; Hui Yan; Shuai Tong; Li-wei Wang; Xiuhai Zhang; Jian-guang Sun (Antonie van Leeuwenhoek, 2020)

Development of a specific AFLP-based SCAR marker for Chinese Race 34MKG of Puccinia graminis f. sp. tritici - Si Chen; Xue Yang; Wen-gong Huang; Yan Liu; Ying Yu; Guang-wen Wu; Shu-quan Zhang; Tian-ya Li; Yuan-yin Cao (Molecular Biology Reports, 2020)

Lipid Production by Rhodotorula glutinis in Continuous Cultivation with a Gravity Sedimentation System - Hongwei Shen; Qiang Li; Xue Yu (Indian Journal of Microbiology, 2020)

Erratum to: LICOM Model Datasets for the CMIP6 Ocean Model Intercomparison Project - Pengfei Lin; Zipeng Yu; Hailong Liu; Yongqiang Yu; Yiwen Li; Jinrong Jiang; Wei Xue; Kangjun Chen; Qian Yang; Bowen Zhao; Jilin Wei; Mengrong Ding; et al. (Advances in Atmospheric Sciences, 2020)

Population Genomics Reveals Shallow Genetic Structure in a Connected and Ecologically Important Fish From the Northwestern Pacific Ocean - Bai-Dong Zhang; Yu-Long Li; Dong-Xiu Xue; Jin-Xian Liu (Frontiers in Marine Science, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

The interaction between dietary marine components and intestinal flora - Lin Li; Chang-Hu Xue; Tian-Tian Zhang; Yu-Ming Wang (Marine Life Science & Technology, 2020)

Evaluation of joint effects of perfluorooctane sulfonate and wood vinegar on planarians, Dugesia japonica - Bin Wang; Danping Li; Zuoqing Yuan; Yuejie Zhang; Xue Ma; Ziheng Lv; Yu Xiao; Jianyong Zhang (Environmental Science and Pollution Research, 2020)

Common source areas of air pollution vary with haze intensity in the Yangtze River Delta, China - Xue Chen; Shaocai Yu; Liqiang Wang; Zhen Li; Yibo Zhang; Mengying Li; Khalid Mehmood; Weiping Liu; Pengfei Li; Eric Lichtfouse; Daniel Rosenfeld; John H. Seinfeld (Environmental Chemistry Letters, 2020)

Effects of Elevated Ozone Concentrations on Root Characteristics and Soil Properties of Elaeocarpus sylvestris and Michelia chapensis - Lan Pan; Wan-qi Lin; Ming Yu; Gan-wen Lie; Li Xue; Hong-yue Chen (Bulletin of Environmental Contamination and Toxicology, 2020)

The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line - Gen-Meng Yang; Lu Li; Feng-Lin Xue; Chen-Li Ma; Xiao-Feng Zeng; Yong-Na Zhao; Dong-Xian Zhang; Yang Yu; Qian-Wen Yan; Yi-Qing Zhou; Shi-Jun Hong; Li-Hua Li (Neurotoxicity Research, 2020)

Development of 19 novel microsatellite markers of lily-of-the-valley (Convallaria, Asparagaceae) from transcriptome sequencing - Qi-Xiang Lu; Jing Gao; Jun-Jie Wu; Xuan Zhou; Xue Wu; Meng-Di Li; Yu-Kun Wei; Rui-Hong Wang; Zhe-Chen Qi; Pan Li (Molecular Biology Reports, 2020)

De novo variants in the Helicase-C domain of CHD8 are associated with severe phenotypes including autism, language disability and overgrowth - Yu An; Linna Zhang; Wenwen Liu; Yunyun Jiang; Xue Chen; Xiaoping Lan; Gan Li; Qiang Hang; Jian Wang; James F. Gusella; Yasong Du; Yiping Shen (Human Genetics, 2020)

Potent antitumor activity of oncolytic adenovirus expressing C/EBPβ against hepatocellular carcinoma - Yan Zeng; Feng-di Li; Jiang-long Du; Yu-jia Xue; Jing Liu; Xin Cao; Hai-zhen Wang (Apoptosis, 2020)

Litorilituus lipolyticus sp. nov., isolated from intertidal sand of the Yellow Sea in China, and emended description of Colwellia asteriadis - Ang Liu; Yan-Jiao Zhang; Qing-Jie Xue; Hui Wang; Yuan-Yuan Yang; Feng Du; Long-Yu Zhao; Hong-Hua Zhang; Yun-Qing Li; Xiu-Zhen Li (Antonie van Leeuwenhoek, 2020)

Classification of mass-transport complexes and distribution of gashydrate-bearing sediments in the northeastern continental slope of the South China Sea - Chao Fu; Xinghe Yu; Xue Fan; Yulin He; Jinqiang Liang; Shunli Li (Frontiers of Earth Science, 2020)

LICOM Model Datasets for the CMIP6 Ocean Model Intercomparison Project - Pengfei Lin; Zhipeng Yu; Hailong Liu; Yongqiang Yu; Yiwen Li; Jirong Jiang; Wei Xue; Kangjun Chen; Qian Yang; Bowen Zhao; Jilin Wei; Mengrong Ding; et al. (Advances in Atmospheric Sciences, 2020)
The datasets of two Ocean Model Intercomparison Project (OMIP) simulation experiments from the LASG/IAP Climate Ocean Model, version 3 (LICOM3), forced by two different sets of atmospheric surface data, are described in this paper. The experiment forced by CORE-II (Co-ordinated Ocean–Ice Reference Experiments, Phase II) data (1948–2009) is called OMIP1, and that forced by JRA55-do (surface dataset for driving ocean–sea-ice models based on Japanese 55-year atmospheric reanalysis) data (1958–2018) is called OMIP2. First, the improvement of LICOM from CMIP5 to CMIP6 and the configurations of the two experiments are described. Second, the basic performances of the two experiments are validated using the climatological-mean and interannual time scales from observation. We find that the mean states, interannual variabilities, and long-term linear trends can be reproduced well by the two experiments. The differences between the two datasets are also discussed. Finally, the usage of these data is described. These datasets are helpful toward understanding the origin system bias of the fully coupled model.

Ketamine Alleviates Fear Generalization Through GluN2B-BDNF Signaling in Mice - Muhammad Asim; Bo Hao; Yu-Han Yang; Bu-Fang Fan; Li Xue; Yan-Wei Shi; Xiao-Guang Wang; Hu Zhao (Neuroscience Bulletin, 2020)

Inhibition of intestinal lipases alleviates the adverse effects caused by high-fat diet in Nile tilapia - Yu-Xue Zhang; Zhe-Yue Jiang; Si-Lan Han; Ling-Yu Li; Fang Qiao; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2020)

Rapid photodegradation of terrestrial soil dissolved organic matter (DOM) with abundant humic-like substances under simulated ultraviolet radiation - Shuaidong Li; Xue Hou; Yu Shi; Tao Huang; Hao Yang; Changchun Huang (Environmental Monitoring and Assessment, 2020)

A solvent-assisted active loading technology to prepare gambogic acid and all-trans retinoic acid co-encapsulated liposomes for synergistic anticancer therapy - Kexin Na; Kai Liu; Jiang Yu; Xue Wang; Meng Li; Chutong Tian; Haixia He; Yuan He; Yongjun Wang (Drug Delivery and Translational Research, 2020)

Bioavailable phosphorus distribution in alpine meadow soil is affected by topography in the Tian Shan Mountains - Fa-Yong Li; Cheng-yu Yuan; Zi-Qiang Yuan; Yong-jun You; Xue-fei Hu; Shan Wang; Guo-yu Li (Journal of Mountain Science, 2020)

Deltamethrin Impairs Honeybees (Apis mellifera) Dancing Communication - Zu Yun Zhang; Zhen Li; Qiang Huang; Xue Wen Zhang; Li Ke; Wei Yu Yan; Li Zhen Zhang; Zhi Jiang Zeng (Archives of Environmental Contamination and Toxicology, 2020)

Identification and Expression Pattern Analysis of Bacterial Blight Resistance Genes in Oryza officinalis Wall ex Watt Under Xanthomonas oryzae Pv. oryzae Stress - Chunmiao Jiang; Suqin Xiao; Dingqin Li; Ling Chen; Qiaofang Zhong; Fuyou Yin; Tengqiong Yu; Xue Ke; Dunyu Zhang; Jian Fu; Yue Chen; Bo Wang; et al. (Plant Molecular Biology Reporter, 2019)
Background Bacterial blight (BB) caused by Xanthomonas oryzae Pv. oryzae ( Xoo ) is one of the most serious diseases of rice worldwide. Oryza officinalis Wall ex Watt, harboring abundant genetic diversity and disease resistance features, are important resources of exploring resistance genes with broad-spectrum resistance to BB. However, the molecular mechanisms and genes of BB resistance in O. officinalis have been rarely explored. Results Here, the BB resistance of four different origin O. officinalis populations in Yunnan were identified by seven representative hypervirulent Xoo races, which exhibited different BB resistance among four populations, in which the BB resistance of the Gengma_Lincang population was the strongest. In addition, the pathogenetic ability of seven Xoo races to O. officinalis was different in that the pathogenicity of PXO99 was stronger than that of C5. There were no remarkable differences in leaf microstructures among four O. officinalis populations, revealing the differences in resistance of four O. officinalis to BB are caused by the endogenous resistance genes. Furthermore, our results proved that there were no nine cloned BB resistance genes in four populations but possessed dominant Xa5 , dominant Xa13 , and recessive xa3/xa26 homologous alleles of xa5 , xa13 , and Xa3 / Xa26 resistance genes. These three homologous genes were isolated and cloned from four populations and named OoXa5 , OoXa13 , and Ooxa3 / xa26 . The expression profile revealed that the expression levels of OoXa13 and Ooxa3/xa26 were significantly down-regulated under PXO99 and C5 stress, especially in the Gengma_Lincang population, suggesting the O. officinalis might enhance BB resistance by down-regulating the expression level of OoXa13 and Ooxa3 / xa26 . Conclusion The BB resistance genes of O. officinalis had its own characteristics by expression pattern and BLAST analysis of OoXa5 , OoXa13 , and Ooxa3 / xa26 , which indicated that there might be new genes or molecular mechanism of BB resistance in O. officinalis. Our studies provided a solid foundation and reference for revealing the molecular mechanism of BB resistance in O. officinalis .

Bioinformatic prediction of critical genes and pathways involved in longevity in Drosophila melanogaster - Jia-qi Li; Dan-dan Duan; Jian-qin Zhang; Yu-zhi Zhou; Xue-mei Qin; Guan-hua Du; Li Gao (Molecular Genetics and Genomics, 2019)

Integrated 3D bioprinting-based geometry-control strategy for fabricating corneal substitutes - Bin Zhang; Qian Xue; Han-yi Hu; Meng-fei Yu; Lei Gao; Yi-chen Luo; Yang Li; Jin-tao Li; Liang Ma; Yu-feng Yao; Hua-yong Yang (Journal of Zhejiang University-SCIENCE B, 2019)

Chachezhania antarctica gen. nov., sp. nov., a novel member of the family ‘Rhodobacteraceae’ isolated from Antarctic seawater - Xiao-xue Yuan; Ning Wang; Meng-yao Zhang; Xiu-lan Chen; Chun-yang Li; Yu-zhong Zhang; Mei Shi; Xi-ying Zhang (Antonie van Leeuwenhoek, 2019)

Carbon-based magnetic nanocomposite as catalyst for persulfate activation: a critical review - Ya Pang; Kun Luo; Lin Tang; Xue Li; Jiangfang Yu; Junyuan Guo; Yuanyuan Liu; Zhu Zhang; Ran Yue; Ling Li (Environmental Science and Pollution Research, 2019)

Cohesion variation during instability evolution of disaster medium in mud inrush of mountain tunnel - Teng Yang; Qing-song Zhang; Xiao Zhang; Xiang-hui Li; Jia-qi Zhang; Yu-xue Sun; Zhuang Li (Journal of Mountain Science, 2019)

Wind and sand control by an oasis protective system: a case from the southeastern edge of the Tengger Desert, China - Yun-hu Xie; Xiao-hong Dang; Zhong-ju Meng; Hong-tao Jiang; Xiao-jia Li; Rui-ping Zhou; Dan-dan Zhou; Xiao-xi Liu; Jing Ding; Xue-qin Wu; Yu-hao Wang; Chun-xing Hai; et al. (Journal of Mountain Science, 2019)

Flavivirga rizhaonensis sp. nov., a marine bacterium isolated from intertidal sand - Ang Liu; Hong-Mei Liu; Feng Du; Shuang Wang; Long-Yu Zhao; Hong-Hua Zhang; Yun-Qing Li; Qing-Jie Xue; Xiu-Zhen Li (Antonie van Leeuwenhoek, 2019)

An expanded allometric model for crowns of four co-existing desert shrubs - Xin-Jun Zheng; Yu-Gang Wang; Xue Wu; Wen Ren; Yu Wu; Yan Li; Xun Cao; Jie Ma; Hai Zhou (Trees, 2019)

Influence of Different Propulsion Speeds on the Characteristics of Mine Pressure in the Fully Mechanized Caving Face During Rotary Stage - Liang Li; Xue He; Yong-qiang Chen; Ya-chun Li; Chen-hao Shi; Yu-ping Zhu (Geotechnical and Geological Engineering, 2019)

De Novo Assembled Transcriptome Analysis and Identification of Genic SSR Markers in Red-Flowered Strawberry - Yan Ding; Li Xue; Rui-xue Guo; Gang-jun Luo; Yu-tong Song; Jia-jun Lei (Biochemical Genetics, 2019)

Genome characterization of the novel lytic Vibrio parahaemolyticus phage vB_VpP_BA6 - Meiyan Yang; Yongjian Liang; Runbin Su; Hanfang Chen; Jing Wang; Jumei Zhang; Yu Ding; Li Kong; Haiyan Zeng; Liang Xue; Haoming Wu; Qingping Wu (Archives of Virology, 2019)

Liver Targeting Albumin-Coated Silybin-Phospholipid Particles Prepared by Nab™ Technology for Improving Treatment Effect of Acute Liver Damage in Intravenous Administration - Cong Lu; Xin Li; Xue Liang; Xinyu Zhang; Tian Yin; Jingxin Gou; Haibing He; Yu Zhang; Xing Tang (AAPS PharmSciTech, 2019)

Dysregulation of Fibroblast Growth Factor 10 in the Peripheral Blood of Patients with Schizophrenia - Yun Yu; Guo-Jun Xie; Yang Hu; Xue-Song Li; Guang-Yang Chen; Guang-En Zheng; Xi Chen; Yong Cheng (Journal of Molecular Neuroscience, 2019)

High-altitude and long-range transport of aerosols causing regional severe haze during extreme dust storms explains why afforestation does not prevent storms - Ping Guo; Shaocai Yu; Liqiang Wang; Pengfei Li; Zhen Li; Khalid Mehmood; Xue Chen; Weiping Liu; Yannian Zhu; Xing Yu; Kiran Alapaty; Eric Lichtfouse; et al. (Environmental Chemistry Letters, 2019)

Importance of thermal adaptation of Amphobotrys ricini in its infection of Asian copperleaf (Acalypha australis) - Lin Yu; Rui Zhang; Xue Li; Guoqing Li; Jing Zhang (Journal of General Plant Pathology, 2019)

Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia - Qin Yang; Hongbo Xiong; Chengqi Xu; Yuan Huang; Xin Tu; Gang Wu; Fenfen Fu; Zhijie Wang; Longfei Wang; Yuanyuan Zhao; Sisi Li; Yufeng Huang; et al. (Molecular Genetics and Genomics, 2019)

F‐box proteins MoFwd1, MoCdc4 and MoFbx15 regulate development and pathogenicity in the rice blast fungus Magnaporthe oryzae - Huan‐Bin Shi; Nan Chen; Xue‐Ming Zhu; Shuang Liang; Lin Li; Jiao‐Yu Wang; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2019)
Summary The Skp1‐Cul1‐F‐box‐protein (SCF) ubiquitin ligases are important parts of the ubiquitin system controlling many cellular biological processes in eukaryotes. However, the roles of SCF ubiquitin ligases remain unclear in phytopathogenic Magnaporthe oryzae . Here, we cloned 24 F‐box proteins and confirmed that 17 proteins could interact with MoSkp1, showing their potential to participate in SCF complexes. To determine their functions, null mutants of 21 F‐box‐containing genes were created. Among them, the F‐box proteins MoFwd1, MoCdc4 and MoFbx15 were found to be required for growth, development and full virulence. Fluorescent‐microscopy observations demonstrated that both MoFbx15 and MoCdc4 were localized to the nucleus, compared with MoFwd1, which was distributed in the cytosol. MoCdc4 and MoFwd1 bound to MoSkp1 via the F‐box domain, the deletion of which abrogated their function. Race tube and qRT‐PCR assays confirmed that MoFwd1 was involved in circadian rhythm by regulating transcription and protein stability of the core circadian clock regulator MoFRQ . Moreover, MoFWD1 also orchestrates conidial germination by influencing conidial amino acids pools and oxidative stress release. Overall, our results indicate that SCF ubiquitin ligases play indispensable roles in development and pathogenicity in M. oryzae .

Isochromanes from Aspergillus fumigatus , an endophytic fungus from Cordyceps sinensis - Xiao-Hua Li; Xue-Hua Han; Ling-Ling Qin; Jun-Lin He; Zhi-Xing Cao; Yu-Cheng Gu; Da-Le Guo; Yun Deng (Natural Product Research, 2019)

Glutamate signaling enhances the heat tolerance of maize seedlings by plant glutamate receptor-like channels-mediated calcium signaling - Zhong-Guang Li; Xin-Yu Ye; Xue-Mei Qiu (Protoplasma, 2019)

Analysis of the microRNA Profile of Coal-Burning Endemic Fluorosis Using Deep Sequencing and Bioinformatic Approaches - Fei Wang; Chen Li; Yu Qin; Xue Han; Jiayu Gao; Aihua Zhang; Peng Luo; Xueli Pan (Bulletin of Environmental Contamination and Toxicology, 2019)

Benthic foraminiferal fauna and sediment provenance of Eocene syn-rift sequences in Taiwan: implication for onset of Asian epi-continental marginal seas off China coast - Chi-Yue Huang; Lei Shao; Ming-Huei Wang; Wei-Guang Xue; Pei-Jun Qiao; Yu-Chi Cui; Yuan-Li Hou (Marine Geophysical Research, 2019)

Membrane biofouling retardation by zwitterionic peptide and its impact on the bacterial adhesion - Si-Yu Wang; Deng-Cheng Han; Chao Song; Meng-Na Li; Muhammad Zaheer Afzal; Shu-Guang Wang; Xue-Fei Sun (Environmental Science and Pollution Research, 2019)

Associations between the red blood cell distribution width and primary angle-closure glaucoma: a potential for disease prediction - Qiang Chen; Bin Zhao; Meng-ya Wang; Xue-yu Chen; Dong Li; Xin-quan Jiang; Jing-hui Tian; Yong-jun Liu (EPMA Journal, 2019)

Ecological vulnerability analysis of Beidagang National Park, China - Xue Yu; Yue Li; Min Xi; Fanlong Kong; Mingyue Pang; Zhengda Yu (Frontiers of Earth Science, 2019)

A Highly Selective Fluorescence “Turn on” and Absorbance-Ratiometric Detection of Al3+ in Totally H2O and its Application in Test Paper - Xue-Jiao Sun; Yu-Qing Ma; Hong Fu; Zhi-Yong Xing; Zhi-Gang Sun; Yue Shen; Jin-Long Li (Journal of Fluorescence, 2019)

Treatment with MQA, a Derivative of Caffeoylquinic Acid, Provides Neuroprotective Effects against Cerebral Ischemia Through Suppression of the p38 Pathway and Oxidative Stress in Rats - Long Chen; Dan-ni Liu; Yu Wang; Xue-ying Liu; Shuai Han; Ke Zhang; Guo-yu Li; Xing Tian; Hang-yu Wang; Jin-hui Wang (Journal of Molecular Neuroscience, 2019)

Tepidicella baoligensis sp. nov., A Novel Member of Betaproteobacterium Isolated from an Oil Reservoir - Jing You; Yongbin Li; Shan Hong; Jing Wang; Jiliang Yu; Bozhong Mu; Xiaochen Ma; Yanfen Xue (Current Microbiology, 2019)

Ethyl lucidenates A reverses P-glycoprotein mediated vincristine resistance in K562/A02 cells - Peng Li; Shi-yu Chen; Shao-xin Shen; Ling-xue Liu; Jian-hua Xu; Zhi-qiang Zhang (Natural Product Research, 2019)

A reliable non-invasive PCR method for takin (Budorcas taxicolor) sex identification based on amelogenin gene - Ming Zhou; Jiaojiao Yu; Rui Xue; Biao Li; Jiandong Yang (Conservation Genetics Resources, 2019)

Complete genome analysis of a novel phage GW1 lysing Cronobacter - Haiyan Zeng; Wenjing He; Chengsi Li; Jumei Zhang; Na Ling; Yu Ding; Liang Xue; Moutong Chen; Haoming Wu; Qingping Wu (Archives of Virology, 2019)

Luminescence chronology of the Palaeolithic–Neolithic transition in the Yujiagou site at the Nihewan Basin, northern China - Xue Rui; Yu‐Jie Guo; Jia‐Fu Zhang; Yue Hu; Hui‐Jie Mei; You‐Ping Wang; Fei Xie; Bo Li (Journal of Quaternary Science, 2019)
The relationship between the Palaeolithic–Neolithic cultural transition and environmental changes is important for understanding human history. However, the timing and nature of human behaviour at the transition, and their relationship to local environmental conditions, remain poorly understood. The Yujiagou archaeological site in the Nihewan Basin, northern China, provides valuable chronological and archaeological information about cultural changes in northern China due to its continuous archaeological sequence of cultural layers from the Palaeolithic to Neolithic. In this study, we apply post‐infrared infrared stimulated luminescence (pIRIR) dating on individual feldspar grains to date the Yujiagou deposits. We provide a revised chronology for the archaeological sequence at the site. We combine these results with multi‐proxy climatic indicators to gain insights into palaeoenvironmental changes in the region. The results show that the age of the artefact‐bearing deposits ranges from 13.5 to 9.7 ka. Polished stones and pottery begin to occur in the archaeological layer around 13 ka, corresponding to a transitional period when the local climate changed from cold to warm. This site provides evidence for understanding the process that led to the regional transition from hunter‐gathering to farming.

Direct and indirect effects of climate on richness drive the latitudinal diversity gradient in forest trees - Chengjin Chu; James A. Lutz; Kamil Král; Tomáš Vrška; Xue Yin; Jonathan A. Myers; Iveren Abiem; Alfonso Alonso; Norm Bourg; David F.R.P. Burslem; Min Cao; Hazel Chapman; et al. (Ecology Letters, 2019)
Climate is widely recognised as an important determinant of the latitudinal diversity gradient. However, most existing studies make no distinction between direct and indirect effects of climate, which substantially hinders our understanding of how climate constrains biodiversity globally. Using data from 35 large forest plots, we test hypothesised relationships amongst climate, topography, forest structural attributes (stem abundance, tree size variation and stand basal area) and tree species richness to better understand drivers of latitudinal tree diversity patterns. Climate influences tree richness both directly, with more species in warm, moist, aseasonal climates and indirectly, with more species at higher stem abundance. These results imply direct limitation of species diversity by climatic stress and more rapid (co‐)evolution and narrower niche partitioning in warm climates. They also support the idea that increased numbers of individuals associated with high primary productivity are partitioned to support a greater number of species.

Coagulation Behavior and Floc Properties of Dosing Different Alkaline Neutralizers into the Fenton Oxidation Effluent - Min Xu; Changyong Wu; Yanan Li; Yuexi Zhou; Hao Xue; Yin Yu (Water, Air, & Soil Pollution, 2018)

Reduced hsa-miR-124-3p levels are associated with the poor survival of patients with hepatocellular carcinoma - Hui-Deng Long; Yu-Shui Ma; Hui-Qiong Yang; Shao-Bo Xue; Ji-Bin Liu; Fei Yu; Zhong-Wei Lv; Ji-Yu Li; Ru-Ting Xie; Zheng-Yan Chang; Gai-Xia Lu; Wen-Ting Xie; et al. (Molecular Biology Reports, 2018)

Generation of Cas9 transgenic zebrafish and their application in establishing an ERV-deficient animal model - Zhe Yang; Shihao Chen; Songlei Xue; Xinxiu Li; Zhen Sun; Yu Yang; Xuming Hu; Tuoyu Geng; Hengmi Cui (Biotechnology Letters, 2018)

Seasonal and Spatial Variability of Water Quality and Nutrient Removal Efficiency of Restored Wetland: A Case Study in Fujin National Wetland Park, China - Nan Li; Xue Tian; Yu Li; Hongchen Fu; Xueying Jia; Guangze Jin; Ming Jiang (Chinese Geographical Science, 2018)

Two new alkylated furan derivatives with antifungal and antibacterial activities from the plant endophytic fungus Emericella sp. XL029 - Xia Wu; Xue-Jiao Pang; Lu-Lin Xu; Ting Zhao; Xin-Yu Long; Qiong-Yin Zhang; Hai-Li Qin; Deng-Feng Yang; Xiao-Long Yang (Natural Product Research, 2018)

Rapid classification of virgin and recycled EPS containers by Fourier transform infrared spectroscopy and chemometrics - Xue-Chao Song; Qin-Bao Lin; Yi-Cai Zhang; Zhong Li; Yu Zeng; Zhi-Feng Chen (Food Additives & Contaminants: Part A, 2018)

The potential adsorption mechanism of the biochars with different modification processes to Cr(VI) - Qiang An; Xue-Qin Li; Hong-Yan Nan; Yang Yu; Jun-Nan Jiang (Environmental Science and Pollution Research, 2018)

Origin of Early Cretaceous Guandian adakitic pluton in central eastern China: partial melting of delaminated lower continental crust triggered by ridge subduction - Ze-Bin Luo; Shuo Xue; Li-Peng Zhang; He Li; Cong-Ying Li; Hong Zhang; Yu-Long Liu; Ming-Xing Ling; Weidong Sun (International Geology Review, 2018)

Catalpol Promotes the Survival and VEGF Secretion of Bone Marrow-Derived Stem Cells and Their Role in Myocardial Repair After Myocardial Infarction in Rats - Xing’ai Ju; Degang Xue; Tongyi Wang; Baiping Ge; Yu Zhang; Zhanquan Li (Cardiovascular Toxicology, 2018)

Development of a TaqMan probe-based quantitative reverse transcription PCR assay for detection of Getah virus RNA - Ning Shi; Hao Liu; Li-xia Li; Bo Hu; Lei Zhang; Chuan-fang Zhao; Xiao-yu Deng; Xin-tong Li; Xiang-hong Xue; Xue Bai; Hai-ling Zhang; Rong-guang Lu; et al. (Archives of Virology, 2018)

Antimicrobial mechanism and the effect of atmospheric pressure N 2 plasma jet on the regeneration capacity of Staphylococcus aureus biofilm - Jiaquan Wang; Zhiyuan Yu; Zimu Xu; Shuheng Hu; Yunxia Li; Xiaojuan Xue; Qiuchen Cai; Xiaoxia Zhou; Jie Shen; Yan Lan; Cheng Cheng (Biofouling, 2018)

Update on the clinical application of deep brain stimulation in sleep dysfunction of Parkinson’s disease - Shuang Zou; Yu-Long Lan; Ya-Ping Hu; Xiao-Xue Yin; Wen-Long Liu; Tao Li; Zhanhua Liang (Acta Neurologica Belgica, 2018)

Neonatal Exposure to Low-Dose (1.2%) Sevoflurane Increases Rats’ Hippocampal Neurogenesis and Synaptic Plasticity in Later Life - Xi Chen; Xue Zhou; Lu Yang; Xu Miao; Di-Han Lu; Xiao-Yu Yang; Zhi-Bin Zhou; Wen-Bin Kang; Ke-Yu Chen; Li-Hua Zhou; Xia Feng (Neurotoxicity Research, 2018)

CGRP gene-modified rBMSCs show better osteogenic differentiation capacity in vitro - Xijiao Yu; Shuang Liu; Hui Chen; Xinyu Zhao; Xue Chen; Yi Du; Shu Li (Journal of Molecular Histology, 2018)

Cytochrome P450 2AA molecular clone, expression pattern, and different regulation by fish oil and lard oil in diets of grass carp (Ctenopharyngodon idella) - Xiao-chen Shi; Jian Sun; Ai Jin; Hong Ji; Hai-bo Yu; Yang Li; Xue-xian Li; Pin Liu; Chao Li; Ji-qin Huang (Fish Physiology and Biochemistry, 2018)

Supercritical carbon dioxide extract of Cinnamomum cassia bark: toxicity and repellency against two stored-product beetle species - Yang Wang; Pei-Pei Dai; Shan-Shan Guo; Ju-Qin Cao; Xue Pang; Zhu-Feng Geng; Yu-Li Sang; Shu-Shan Du (Environmental Science and Pollution Research, 2018)

Impact of Land Use Change on Hydrologic Processes in a Large Plain Irrigation District - Xiao-Bo Luan; Pu-Te Wu; Shi-Kun Sun; Xiao-Lei Li; Yu-Bao Wang; Xue-Rui Gao (Water Resources Management, 2018)