Study of the effect of intestinal immunity in neonatal piglets coinfected with porcine deltacoronavirus and porcine epidemic diarrhea virus - Jixiang Liang; Yang Li; Zhishan Yan; Zhe Jiao; Dapeng Peng; Wanpo Zhang (Archives of Virology, 2022)

Chemical characteristics and cytotoxic correlation analysis of PM2.5 in Jinan - Xinli Wang; Minmin Yang; Guirong Wang; Lili Du; Haiyan Li; Yan Wang (Air Quality, Atmosphere & Health, 2022)

Effects of Plant Community Type on Soil Methane Flux in Semiarid Loess Hilly Region, Central Gansu Province, China - Chuanjie Yang; Guang Li; Lijuan Yan; Weiwei Ma; Jiangqi Wu; Yan Tan; Shuainan Liu; Shikang Zhang (Advances in Atmospheric Sciences, 2022)

Transcriptome study on immune response against Vibrio parahaemolyticus challenge in gill of abalone Haliotis discus hannai Ino - Yan Fang; Xiyun Yang; Shujuan Zhang; Xuyang Chen; Gang Lin; Yuqing Zhang; Mengjiao Wang; Mingzhu Li (Frontiers in Marine Science, 2022)
Abalone ( Haliotis discus hannai Ino) is one of the most vital economic shellfish cultured in China. However, bacterial and viral infection often leads to its high mortality and serious economic losses. In this study, transcriptome sequencing was performed on gill of abalone challenged by Vibrio parahaemolyticus for 0 h (control group, A0h), 8 h (A8h), and 48 h (A48h), respectively. Each library has an average of 53,361,675 clean reads. Approximately 85.71% reads were mapped to the reference genome of Haliotis discus hannai Ino. In comparison with A0h group, 7,656 and 2,789 genes were differentially expressed in the A8h and A48h groups, respectively. The differentially expressed genes (DEGs) were mostly enriched in oxidation–reduction process and oxidoreductase activity from GO analysis as well as immunity and metabolism-related pathways from Kyoto Encyclopedia of Genes and Genomes analysis. Cluster analysis demonstrated that all DEGs were categorized into eight subclusters by adopting the gene expression model. Specifically, a total of 1,070 significantly downregulated genes from two clusters were related to some metabolic pathways, ABC transporters, and cell adhesion. Moreover, 212 upregulated genes in one subcluster were enriched in several immune-related pathways, including nucleotide-binding oligomerization domain (NOD)-like receptor signaling pathway and apoptosis. Some members of the pattern recognition receptors family, which can initiate inflammatory signaling and induce apoptosis, were stimulated to upregulate in gill after challenge including C1q, perlucin, and low-density lipoprotein receptor–related protein. In addition, caspase-dependent apoptosis pathway was inactive, whereas caspase-independent apoptosis pathway was stimulating in response to Vibrio challenge. To eliminate invading pathogen, the immune effectors such as interleukin-17, matrix metalloproteinase, lysozyme, superoxide, and ferritin were also stimulated in gill. Moreover, this study also provides more information for comprehending the immunity and defense mechanisms against V. parahaemolyticus infection in abalone.

Meta-analysis of the effect of melatonin application on abiotic stress tolerance in plants - Xiaoxiao Yang; Jianhong Ren; Juanjuan Li; Xinyue Lin; Xiangyu Xia; Wenjie Yan; Yuxin Zhang; Xiping Deng; Qingbo Ke (Plant Biotechnology Reports, 2022)

Four new polyacetylenes from the roots of Saposhnikovia divaricata - Yan Sun; Yan-Ping Sun; Yan Liu; Juan Pan; Wei Guan; Xiao-Mao Li; Yuan Liu; Anam Naseem; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Promoted reductive removal of chlorinated organic pollutants co-occurring with facilitated methanogenesis in anaerobic environment: A systematic review and meta-analysis - Jie Cheng; Jing Yuan; Shuyao Li; Xueling Yang; Zhijiang Lu; Jianming Xu; Yan He (Critical Reviews in Environmental Science and Technology, 2022)

Effects of Heavy Metal Ions on Microbial Reductive Dechlorination of 1, 2-Dichloroethane and Tetrachloroethene - Jingjing Wang; Xiuying Li; Jun Yan; Yi Yang (Frontiers in Marine Science, 2022)
Microbial reductive dechlorination has been considered an effective process for the clean-up of organohalide-contaminated sites. Heavy metal ions are commonly present as co-contaminants in various organohalide-contaminated sites. To understand the impacts of heavy metal ions on the environmental fate of organohalides, we investigated the effects of Zn 2+ , Cu 2+ and Cd 2+ on reductive dechlorination of tetrachloroethene (PCE) and 1,2-dichloroethane (1,2-DCA) in sediment microcosms and transferred enrichment cultures. PCE and 1,2-DCA-dechlorinating enrichment cultures could be consecutively transferred in the presence of up to 10 mg/L Cu 2+ or 10 mg/L Zn 2+ ; by comparison, up to 50 mg/L Cd 2+ had minor impacts on the microbial reductive dechlorination of PCE and 1,2-DCA. The inhibitory effects of tested heavy metal ions on microbial reductive dechlorination ranked in descending order are Zn 2+ , Cu 2+ , and Cd 2+ . Community profiling and principal component analysis indicate that the concentration and type of contaminants (e.g., heavy metal ions, organohalides) shaped the microbial community structure, an observation similar to a prior report. The enrichment of certain organohalide-respring bacteria (e.g., Dehalococcoides , Dehalogenimonas ) during continuous transfers exposed to heavy metal ions suggests that they are capable of tolerating high concentrations of heavy metal ions. Our findings provide insights into the impacts of heavy metal ions on microbial reductive dechlorination and may be helpful for in situ bioremediation at sites contaminated with organohalides and heavy metals.

OsAPL controls the nutrient transport systems in the leaf of rice (Oryza sativa L.) - Zhen Yan; Man-Yu Yang; Biligen-Gaowa Zhao; Guo Li; Qing Chao; Feng Tian; Ge Gao; Bai-Chen Wang (Planta, 2022)

Beta-Boswellic Acid Protects Against Cerebral Ischemia/Reperfusion Injury via the Protein Kinase C Epsilon/Nuclear Factor Erythroid 2-like 2/Heme Oxygenase-1 Pathway - Mingming Wang; Jiaoyan Yu; Qi Yang; Chao Guo; Wei Zhang; Weiwei Li; Yan Weng; Yi Ding; Jingwen Wang (Molecular Neurobiology, 2022)

Effects of ciprofloxacin on Eichhornia crassipes phytoremediation performance and physiology under hydroponic conditions - Yang Deng; Xiyi Qian; Yiting Wu; Tian Ma; Xiaoguang Xu; Jiayi Li; Guoxiang Wang; Yan Yan (Environmental Science and Pollution Research, 2022)

Bioleaching Performance of Titanium from Bauxite Residue Under a Continuous Mode Using Penicillium Tricolor - Yang Qu; Hui Li; Ben Shi; Hannian Gu; Guangxuan Yan; Zipeng Liu; Ruizhi Luo (Bulletin of Environmental Contamination and Toxicology, 2022)

A TMT-based shotgun proteomics uncovers overexpression of thrombospondin 1 as a contributor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome - Weiqian Wang; Yan Chen; Yue Yin; Xunjiang Wang; Xuanling Ye; Kaiyuan Jiang; Yi Zhang; Jiwei Zhang; Wei Zhang; Yuzheng Zhuge; Li Chen; Chao Peng; et al. (Archives of Toxicology, 2022)
Hepatic sinusoidal obstruction disease (HSOS) is a rare but life-threatening vascular liver disease. However, its underlying mechanism and molecular changes in HSOS are largely unknown, thus greatly hindering the development of its effective treatment. Hepatic sinusoidal endothelial cells (HSECs) are the primary and essential target for HSOS. A tandem mass tag-based shotgun proteomics study was performed using primary cultured HSECs from mice with HSOS induced by senecionine, a representative toxic pyrrolizidine alkaloid (PA). Dynamic changes in proteome were found at the initial period of damage and the essential role of thrombospondin 1 (TSP1) was highlighted in PA-induced HSOS. TSP1 over-expression was further confirmed in human HSECs and liver samples from patients with PA-induced HSOS. LSKL peptide, a known TSP1 inhibitor, protected mice from senecionine-induced HSOS. In addition, TSP1 was found to be covalently modified by dehydropyrrolizidine alkaloids in human HSECs and mouse livers upon senecionine treatment, thus to form the pyrrole-protein adduct. These findings provide useful information on early changes in HSECs upon PA treatment and uncover TSP1 overexpression as a contributor in PA-induced HSOS. Graphical abstract

Microbiota profiling on itchy scalp with undetermined origin - Xuejing Li; Fang Yang; Haosong Yan; Yi Shi; Xiaowei Chang; Mengmeng Zhang; Yan Zhang; Menghui Zhang (Archives of Microbiology, 2022)

Retiboletus atrofuscus (Boletaceae, Boletales), a new species from China - Fan Zhou; Yang Gao; Hai-Yan Song; Hai-Jing Hu; Shuo-Xi Li; Jin-Hao Liu; Dian-Ming Hu (Archives of Microbiology, 2022)

Aquapteridospora jiangxiensis, a new aquatic hyphomycetous fungus from a freshwater habitat in China - Su-Qin Peng; Yu-Lin Liu; Jun-En Huang; Xiao-Hong Li; Xin-Yi Yan; Hai-Yan Song; Yang Gao; Zhi-Jun Zhai; Yuan-Qiu Liu; Dian-Ming Hu (Archives of Microbiology, 2022)

Amelioration of Flesh Quality in Hybrid Grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatu) Fed With Oxidized Fish Oil Diet by Supplying Lactobacillus pentosus - Xiaobo Yan; Simiao Pan; Zhihao Li; Xiaohui Dong; Beiping Tan; Shuisheng Long; Tao Li; Xiangxiang Suo; Yuanzhi Yang (Frontiers in Marine Science, 2022)
The objective was to investigate the improvement of the flesh quality and nutritional value of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatu ) by Lactobacillus pentosus (BL-15). The two diets were prepared with 9% oxidized fish oil (OFO negative control group) or 9% fresh fish oil (FFO positive control group) as the major lipid source, and the OFO diet were sprayed with L. pentosus at 1.0×10 7 , 1.0×10 8 , 1.0×10 9 CFU/g, respectively. Five kinds of diets were fed to hybrid grouper with initial weight of 21.36 ± 0.03 g for 60 days. The results showed that (1) consumption of OFO diet significantly increased muscle crude lipid, total cholesterol, and total monounsaturated fatty acids contents and significantly decreased muscle C20:5n3, C22:6n3, ∑PUFA levels of grouper ( p < 0.05), whereas the addition of L. pentosus to OFO diet significantly reduced muscle crude lipid, malondialdehyde, reactive oxygen radicals, total cholesterol concentration, increased C20:5n3, C22:6n3, ∑PUFA levels, increased muscle crude protein content, and enhanced muscle hardness, gumminess, and chewiness compared with FFO or OFO group ( p < 0.05). (2) In addition, ingestion of OFO diet significantly increased muscle phenylalanine content and significantly decreased aspartic acid content ( p < 0.05), while the addition of L. pentosus restored aspartic acid to the level not significantly different from that of FFO group ( p > 0.05). The addition of L. pentosus also increased tyrosine, lysine, leucine, phenylalanine, arginine, and alanine content compared to FFO group at the same time ( p < 0.05). (3) Furthermore, the intake of OFO diet would lead to deterioration in muscle flavor quality and increase in noxious odors in grouper, and the addition of L. pentosus can mitigate or rectify these detrimental consequences. In further analysis, consumption of OFO group significantly downregulated the mRNA expression of muscle growth factors and caused serious damage to the muscle antioxidant system ( p < 0.05), which was protected against by the potent antioxidant properties of L. pentosus . We recommend the supplementation level of L. pentosus to be 1.0×10 9 CFU/g under the highly oxidized conditions of the present trial fish oil.

The R2R3-MYB transcription factor VcMYB4a inhibits lignin biosynthesis in blueberry (Vaccinium corymbosum) - Bofei Yang; Yuening Li; Yan Song; Xianglong Wang; Qingxun Guo; Lianxia Zhou; Xue Xue; Chunyu Zhang (Tree Genetics & Genomes, 2022)

High On-Treatment Platelet Reactivity as Predictor of Long-term Clinical Outcomes in Stroke Patients with Antiplatelet Agents - Huihui Lv; Zidong Yang; Haibo Wu; Mingyuan Liu; Xiaowei Mao; Xu Liu; Hongyan Ding; Zhuqing Shi; Yang Zhou; Qianyun Liu; Yongkang Zhang; Yinting Zhou; et al. (Translational Stroke Research, 2022)

Large-scale evaluation of aluminum tolerance in maize (Zea mays L.) acessions - Jianzhou Ding; Wei Yang; Xiaoqi Hu; Weina Yan; Wanpeng Hu; Hongjie Li; Chan Liu; Wenzhu He; Yanli Lu; Shibin Gao; Suzhi Zhang (Theoretical and Experimental Plant Physiology, 2022)

CD146 as a promising therapeutic target for retinal and choroidal neovascularization diseases - Bai Xue; Ping Wang; Wenzhen Yu; Jing Feng; Jie Li; Rulian Zhao; Zhenglin Yang; Xiyun Yan; Hongxia Duan (Science China Life Sciences, 2022)

CircWHSC1 expedites cervical cancer progression via miR-532-3p/LTBP2 axis - Yan Li; Fandong Meng; Chengguang Sui; Yang Wang; Dali Cheng (Molecular and Cellular Biochemistry, 2022)

Phomopsis liquidambaris Increases Rice Mineral Uptake Under Waterlogging Condition via the Formation of Well-Developed Root Aerenchyma - Li-Yan Hu; Yang Yang; Hao Wu; Meng-Jun Tang; Xing-Guang Xie; Chuan-Chao Dai (Journal of Plant Growth Regulation, 2022)

Testing the isotopic equilibrium fractionation on active speleothem based on cave monitoring - Yang-Yang Huang; Ting-Yong Li; Chao-Jun Chen; Ran Huang; Tao Wang; Yao Wu; Si-Ya Xiao; Yu-Zhen Xu; Hai-Ying Qiu; Yan Yang; Jun-Yun Li (Journal of Earth System Science, 2022)

Spatial relationship among the density of Culex tritaeniorhynchus, Anopheles sinensis, human dwellings and pigsty in Guangxi, China: modelling study - Mei-De Liu; Chun-Xiao Li; Xiang-Yang Feng; Yan-De Dong; Mi-You Yi; Tong-Yan Zhao (International Journal of Tropical Insect Science, 2022)

Long-term exercise pre-training attenuates Alzheimer’s disease–related pathology in a transgenic rat model of Alzheimer’s disease - Luodan Yang; Chongyun Wu; Yong Li; Yan Dong; Celeste Yin-Chieh Wu; Reggie Hui-Chao Lee; Darrell W. Brann; Hung Wen Lin; Quanguang Zhang (GeroScience, 2022)

Rapid and specific detection of Fusarium acuminatum and Fusarium solani associated with root rot on Astragalus membranaceus using loop-mediated isothermal amplification (LAMP) - Yan Wang; Chunwei Wang; Yurong Ma; Xiqian Zhang; Hongbin Yang; Guangxin Li; Xinfeng Li; Meiqin Wang; Xiaojun Zhao; Jianming Wang; Xianhong Zhang (European Journal of Plant Pathology, 2022)

Degradation of the typical herbicide atrazine by UV/persulfate: kinetics and mechanisms - Yucan Liu; Xianguo Ji; Jingjie Yang; Wei Tang; Yuliang Zhu; Ying Wang; Yanxiang Zhang; Yan Zhang; Jinming Duan; Wei Li (Environmental Science and Pollution Research, 2022)

Combined game model and investment decision making of power grid-distributed energy system - Yongxiu He; Wei Xiong; Binyou Yang; Hai-yan Yang; Jiu-fang Zhou; Ming-li Cui; Yan Li (Environment, Development and Sustainability, 2022)

Alterations of dynamic functional connectivity between visual and executive-control networks in schizophrenia - Weiliang Yang; Xuexin Xu; Chunxiang Wang; Yongying Cheng; Yan Li; Shuli Xu; Jie Li (Brain Imaging and Behavior, 2022)

Mitigation of microbial corrosion by Cu addition to X65 pipeline steel by Pseudomonas aeruginosa MCCC 1A00099 - Yuchen Li; Xianbo Shi; Jiguang Li; Yunpeng Zeng; Minggang Shen; Wei Yan; Ke Yang (Archives of Microbiology, 2022)

Toxic encephalopathy induced by radix Sophorae tonkinensis - Xue-Lin Li; Hao-Tian Zhao; Jinming Han; Zhong-Rui Yan; Hai-Yang Wang (Acta Neurologica Belgica, 2022)

Counter-rotating eddy pair in the Luzon Strait - Ruili Sun; Peiliang Li; Yanzhen Gu; Fangguo Zhai; Yunwei Yan; Bo Li; Yang Zhang (Ocean Science, 2022)
Based on satellite remote-sensing observation data and Hybrid Coordinate Ocean Model (HYCOM) re-analysis data, we studied the counter-rotating eddy pair in the Luzon Strait (LS). Statistical analysis reveals that when an anti-cyclonic mesoscale eddy (AE) (cyclonic mesoscale eddy [CE]) in the Northwest Pacific (NWP) gradually approaches the east side of the LS, a CE (an AE) gradually forms on the west side of the LS, and it is defined as the AE (CE) mode of the counter-rotating eddy pair in the LS. The counter-rotating eddy pair exhibits obvious seasonal variation: the AE mode mainly occurs in the summer half of the year, while the CE mode mainly occurs in the winter half of the year. The mean durations of the AE and CE modes are both approximately 70 d. Based on the vorticity budget equation and energy analysis, the dynamic mechanism of counter-rotating eddy-pair occurrence is determined to be as follows: the AE (CE) on the east side of the LS causes a positive (negative) vorticity anomaly through horizontal velocity shear on the west side of the LS, and the positive (negative) vorticity anomaly is transported westward by the zonal advection of the vorticity, finally leading to the formation of the CE (AE) on the west side of the LS.

Development and characterization of 123 SNPs in an endangered fish Semilabeo obscurus - Shikai Li; Wei Wang; Mingju Yang; Fujiang Huang; Xue Wang; Sheng Zeng; Yan Xiang; Lu Zhou (Conservation Genetics Resources, 2022)

Prediction Method and Validation Study of Tensile Performance of Reinforced Armor Layer in Marine Flexible Pipe/Cables - Hualin Wang; Zhixun Yang; Jun Yan; Gang Wang; Dongyan Shi; Baoshun Zhou; Yanchun Li (Journal of Marine Science and Engineering, 2022)
Marine flexible pipe/cables, such as umbilicals, flexible pipes and cryogenic hoses, are widely adopted in ocean engineering. The reinforcing armor layer in these pipe/cables is the main component for bearing loads, which is a typical multi-layer helically wound slender structure with different winding angles for different devices. There has been no general theoretical methodology to describe the tensile performance of these flexible pipe/cables. This paper first introduces a theory to solve the tensile mechanical behavior of a helically wound structure. Based on the curved beam theory, a solution of the tensile stress of a helically wound slender is derived. Then, the deformation mechanism of the marine flexible pipe/cables structure with different winding angles is studied. Through comparing theoretical and numerical results, the deformation characteristic of the helically wound slender structure is further explained. It is found that a sectional torsional deformation generates when the structure with a larger winding angle is under tension condition, while the sectional deformation of the structure with a smaller winding angle is mainly tension. Finally, a couple types of marine flexible pipe/cables under the tension condition are provided to analyze the mechanical performance and compare the difference between different theoretical models. The research conclusion from this paper provides a useful reference for the structural analysis and design of marine flexible pipe/cables.

Phenolic compounds from the sclerotia of Inonotus obliquus - Yan-Mei Wei; Li Yang; Wen-Li Mei; Hui-Qin Chen; Cai-Hong Cai; Wei Li; Wen-Hua Dong; Zhi-Bao Chen; Hao-Fu Dai (Natural Product Research, 2022)

Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model - Wan-yi Li; Jun-yan Gao; Su-Yang Lin; Shao-tao Pan; Biao Xiao; Yu-tao Ma; Kai Xie; Wei Shen; Zhi-tao Liu; Guang-yu Li; Jie-jie Guo; Qin-wen Wang; et al. (Molecular Neurobiology, 2022)

SOCE-mediated NFAT1–NOX2–NLRP1 inflammasome involves in lipopolysaccharide-induced neuronal damage and Aβ generation - Zhenghao Sun; Xuewang Li; Liu Yang; Xianan Dong; Yuli Han; Yan Li; Jing Luo; Weizu Li (Molecular Neurobiology, 2022)

Quercetin Alleviates Demyelination Through Regulating Microglial Phenotype Transformation to Mitigate Neuropsychiatric Symptoms in Mice with Vascular Dementia - Zihu Tan; Guang Yang; Jing Qiu; Wenjing Yan; Yu Liu; Zhengling Ma; Jia Li; Jing Liu; Nan Shan (Molecular Neurobiology, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

A Significant Fluorescent Aptamer Sensor Based on Carbon Dots and Graphene Oxide for Highly Selective Detection of Progesterone - Hanyue Cui; Huan Lu; Jing Yang; Yao Fu; Yan Huang; Li Li; Yaping Ding (Journal of Fluorescence, 2022)

The genes for sensory perception of sound should be considered in gene diagnosis of congenital sensorineural hearing loss and microtia - Ken Lin; Ding-Yun You; Li-Huan Zhang; Li-Juan Zhou; Jin-Yan Zu; Yang Xiao; Mei-Hua Sun; Dong-Su; Xue Cao; Tie-Song Zhang; Jing Ma (Journal of Applied Genetics, 2022)

Phenotypic plasticity of light use favors a plant invader in nitrogen‐enriched ecosystems - Xiao Xu; Chenhao Zhou; Qiang He; Shiyun Qiu; Yan Zhang; Ji Yang; Bo Li; Ming Nie (Ecology, 2022)
Eutrophication is believed to promote plant invasion, resulting in high growth performances of invasive plants and, therefore, the great potential for growth‐induced intraspecific competition for light. Current hypotheses predict how eutrophication promotes plant invasion but fail to explain how great invasiveness is maintained under eutrophic conditions. In diverse native communities, co‐occurring plants of varying sizes can avoid light competition by exploiting light complementarily; however, whether this mechanism applies to intraspecific competition in invasive plant populations remains unknown. Using a 2‐year field nitrogen (N)‐enrichment experiment on one of the global invasive plants, Spartina alterniflora , we found that the plasticity of light use reduced intraspecific competition and increased biomass production in S. alterniflora . This plasticity effect was enhanced when S. alterniflora had no nutrient limitations. In the N‐enrichment treatments, the height difference among S. alterniflora ramets increased as light intensity decreased under the canopy. Compared with ambient N, under N enrichment, shorter individuals increased their light‐use efficiency and specific leaf area in response to the reduced light intensity under the canopy. However, such ecophysiological plasticity was not found for taller individuals. Our findings revealed that the light‐use plasticity of short individuals can be envisaged as a novel mechanism by which an invasive plant alleviates intraspecific competition and increases its invasiveness, challenging the prevailing perspective that the invasiveness of exotic plants is constrained by intraspecific competition.

Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities - Ying-Ying Chen; Jiang-Ping Hou; Ling Huang; Afsar Khan; Fei-Fei Xing; Xiao-Han Zhang; De-Feng Han; Shi-Li Yan; Gui-Dong Cao; Qi-Yang Jiao; Dejie Liu; Xuwei Zhu; et al. (Natural Product Research, 2022)

Two new dammarane-type triterpenoids from the green walnut husks of Juglans mandshurica Maxim - Yuan-Yuan Zhou; Hui-Rui Gao; Hong-Juan Song; Dan-Da Ma; Xiao-Juan Zhang; Yan-Ping Sun; Yan Liu; Xiao-Li Wang; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Five new phloroglucinol derivatives from Syzygium brachyantherum and their α -glucosidase and PTP1B inhibitory activities - Wen Xu; Shao-Hua Xu; Li Wang; Zhen Zang; Yan Zhao; Jing-Ping Liu; Jing Yang; Yong Zhao (Natural Product Research, 2022)

Assessment of spatiotemporal variability of precipitation using entropy indexes: a case study of Beijing, China - Longgang Du; Xinxin Li; Moyuan Yang; Bellie Sivakumar; Yanxin Zhu; Xingyao Pan; Zhijia Li; Yan-Fang Sang (Stochastic Environmental Research and Risk Assessment, 2022)

Effects of mowing frequency on abundance, genus diversity and community traits of soil nematodes in a meadow steppe in northeast China - F. J. Pan; L. Y. Yang; C. L. Wang; R. R. Yan; C. J. Li; Y. F. Hu; Y. Jiang; J. Cao; H. Y. Tan; X. P. Xin (Plant and Soil, 2022)

Changes of community composition strengthen the positive effects of nitrogen deposition on litter N:P stoichiometry in a semi-arid grassland - Shuang-Li Hou; Jun-Jie Yang; Jiang-Xia Yin; Hai-Wei Wei; Yan-Yu Hu; Zhi-Wei Zhang; Guo-Jiao Yang; Xiao-Tao Lü (Plant and Soil, 2022)

Astragaloside IV suppresses migration and invasion of TGF-β1-induced human hepatoma HuH-7 cells by regulating Nrf2/HO-1 and TGF-β1/Smad3 pathways - Lili Li; Qin Wang; Yinghao He; Liangjie Sun; Yan Yang; Xiaonan Pang (Naunyn-Schmiedeberg's Archives of Pharmacology, 2022)

Analysis of the microseismicity characteristics in landslide dam failure flume tests: implications for early warning and dynamics inversion - Yunpeng Yang; Guan Chen; Xingmin Meng; Shiqiang Bian; Yan Chong; Wei Shi; Wanyu Jiang; Jiacheng Jin; Chen Li; Xinliang Mu; Dongxia Yue (Landslides, 2022)

Regulation of endothelial progenitor cell functions during hyperglycemia: new therapeutic targets in diabetic wound healing - Gui Wan; Yangyang Chen; Jing Chen; Chengqi Yan; Cheng Wang; Wenqing Li; Renqun Mao; Hans-Günther Machens; Xiaofan Yang; Zhenbing Chen (Journal of Molecular Medicine, 2022)

Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice - Ximei Cao; Yindi Yan; Xuguang Luo; Xinhua Yang; Huilin Cui; Yanping Yang; Hairong Li (Journal of Molecular Histology, 2022)

End-to-End Depression Recognition Based on a One-Dimensional Convolution Neural Network Model Using Two-Lead ECG Signal - Xiaohan Zang; Baimin Li; Lulu Zhao; Dandan Yan; Licai Yang (Journal of Medical and Biological Engineering, 2022)

Protocatechuic acid protects mice from influenza A virus infection - Qian Wang; Xiaojuan Ren; Jinhua Wu; Hongrong Li; Liu Yang; Yan Zhang; Xin Wang; Zhicun Li (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

A genetic-based population PK/PD modeling of methadone in Chinese opiate dependence patients - Dong Guo; Zhirong Tan; Xiaoya Lou; Shan Shi; Yan Shu; Honghao Zhou; Li Yu; Hong Yang (European Journal of Clinical Pharmacology, 2022)

Indoor air pollution from solid fuel on children pneumonia in low- and middle-income countries: a systematic review and meta-analysis - Tianming Chen; Chao Zou; Yang Yuan; Jingjing Pan; Baoping Zhang; Liang Qiao; Yanping Li; Jia-yan Qian; Qingyuan Guo; Ye Yuan; Cheng Ding (Environmental Science and Pollution Research, 2022)

RETRACTED ARTICLE: The spillover of tourism development on CO2 emissions: a spatial econometric analysis - Yan Jiaqi; Song Yang; Yu Ziqi; Li Tingting; Brian Sheng Xian Teo (Environmental Science and Pollution Research, 2022)

Catastrophe instability analysis of rock slopes with locked segments in open-pit mine due to freeze–thaw weathering - Chen Qiao; Yu Wang; Changhong Li; Bingqian Yan; Heping Yang; Yonggang Xiao (Bulletin of Engineering Geology and the Environment, 2022)

Heavy Metal Pollution Analysis and Health Risk Assessment of Two Medicinal Insects of Mylabris - Xi Yang; Yubo Tian; Haibo Liu; Yan Ren; Zhuo Yang; Xiang Li; Chao Du; Changhua Liu; Faming Wu (Biological Trace Element Research, 2022)

Humic Acid and Iron Chelation Modified Anode Improves the Electrochemical Performance of Marine Sediment Microbial Fuel Cell - Yubin Fu; Jiaqi Chen; Yan Chen; Xiang Huang; Yang Li; Huaijing Zhang; Xuerong Zai (Journal of Ocean University of China, 2022)

Ore-forming age and tectonic setting of the Linjiasandaogou gold deposit in the Liaodong Peninsula, northeast China: constraints from geochronology and geochemistry - Xiaofeng Yao; Tingjie Yan; Zhicheng Lü; Chenggui Lin; Kuifeng Mi; Shenghui Li; Yang Li; Wange Du (Acta Geochimica, 2022)

Lower activity time constraint on the ore-controlling Erdaogou fault in the Qingchengzi orefield of the Liaodong Peninsula, NE China - Yan Zhao; Yuewen Feng; Peng Zhang; Linlin Kou; Zhongzhu Yang; Shenghui Li; Wei Wang (Acta Geochimica, 2022)

A trait‐based model ensemble approach to design rice plant types for future climate - Livia Paleari; Tao Li; Yubin Yang; Lloyd T. Wilson; Toshihiro Hasegawa; Kenneth J. Boote; Samuel Buis; Gerrit Hoogenboom; Yujing Gao; Ermes Movedi; Françoise Ruget; Upendra Singh; et al. (Global Change Biology, 2022)
Crop models are powerful tools to support breeding because of their capability to explore genotype × environment×management interactions that can help design promising plant types under climate change. However, relationships between plant traits and model parameters are often model specific and not necessarily direct, depending on how models formulate plant morphological and physiological features. This hinders model application in plant breeding. We developed a novel trait‐based multi‐model ensemble approach to improve the design of rice plant types for future climate projections. We conducted multi‐model simulations targeting enhanced productivity, and aggregated results into model‐ensemble sets of phenotypic traits as defined by breeders rather than by model parameters. This allowed to overcome the limitations due to ambiguities in trait‐parameter mapping from single modelling approaches. Breeders' knowledge and perspective were integrated to provide clear mapping from designed plant types to breeding traits. Nine crop models from the AgMIP‐Rice Project and sensitivity analysis techniques were used to explore trait responses under different climate and management scenarios at four sites. The method demonstrated the potential of yield improvement that ranged from 15.8% to 41.5% compared to the current cultivars under mid‐century climate projections. These results highlight the primary role of phenological traits to improve crop adaptation to climate change, as well as traits involved with canopy development and structure. The variability of plant types derived with different models supported model ensembles to handle related uncertainty. Nevertheless, the models agreed in capturing the effect of the heterogeneity in climate conditions across sites on key traits, highlighting the need for context‐specific breeding programmes to improve crop adaptation to climate change. Although further improvement is needed for crop models to fully support breeding programmes, a trait‐based ensemble approach represents a major step towards the integration of crop modelling and breeding to address climate change challenges and develop adaptation options.

Fine mapping KT1 on wheat chromosome 5A that conditions kernel dimensions and grain weight - Zhongxin Kong; Ruiru Cheng; Haisheng Yan; Haiyun Yuan; Yong Zhang; Guoqiang Li; Haiyan Jia; Shulin Xue; Wenling Zhai; Yang Yuan; Zhengqiang Ma (Theoretical and Applied Genetics, 2022)

Decreased peripheral mtDNA in methamphetamine use disorder - Ling-Yan Su; Yuan Li; Qianjin Liu; Lijin Jiao; Jing Shen; Lu-Xiu Yang; Ti-Fei Yuan; Yong-Gang Yao (Science China Life Sciences, 2022)

Baicalin attenuates amyloid β oligomers induced memory deficits and mitochondria fragmentation through regulation of PDE-PKA-Drp1 signalling - Hai-Yang Yu; Ye Zhu; Xin-Li Zhang; Lei Wang; Yan-Meng Zhou; Fang-Fang Zhang; Han-Ting Zhang; Xiao-Min Zhao (Psychopharmacology, 2022)

Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa - Yan Hui Yang; Mu Rong Yang; Jian Yu Zhu; Ke Wei Dong; Yan Jie Yi; Rui Fang Li; Lei Zeng; Chang Fu Zhang (Planta, 2022)

Analysis of expression profiles and bioinformatics suggests that plasma exosomal circular RNAs may be involved in ischemic stroke in the Chinese Han population - Bingyi Xu; Xianli Huang; Yan Yan; Zhi Zhao; Jialei Yang; Lulu Zhu; Yibing Yang; Baoyun Liang; Lian Gu; Li Su (Metabolic Brain Disease, 2022)

Effect of Straw Return and Nitrogen Application Rate on the Photosynthetic Characteristics and Yield of Double-Season Maize - Yan Qiong Pan; Shahbaz Atta Tung; Li Yang; Yong Wang; Xun Bo Zhou (Journal of Soil Science and Plant Nutrition, 2022)

Effect of Fertilization Regimes and Seasonal Change on nosZ-Denitrifying Bacterial Community in a Double-Rice Paddy Field - Jiangwen Nie; Yong Zhou; Wei Yang; Shaoqiu Li; Haoxuan Li; Jianwei Wu; Chengwei Li; Xiaoyuan Yan; Rong Zhu; Bo Zhu; Zhangyong Liu (Journal of Soil Science and Plant Nutrition, 2022)

Optimizing Method of Main Caverns in Large Underground Water-Sealed Storage Cavern - Yang An; E-Chuan Yan; Xing-Ming Li; Shao-Ping Huang (Geotechnical and Geological Engineering, 2022)

Toxicity of ammonia to larvae and juveniles of the geoduck clam Panopea japonica - Fan Wang; Cuicui Li; Wen Zhao; MD. Habibur Rahman; Ye Wang; Feng Yang; Zhongming Huo; Lei Fang; Xiwu Yan (Fisheries Science, 2022)

Analysis of geomorphologic features of the circular structure in the south of Lufeng Dinosaur Valley - Hu Lin; Gan Shu; Yuan Xiping; Yang MingLong; Gao Sha; Bi Rui; Li Yan (Earth Science Informatics, 2022)

The antioxidant activities of flavonoids in Jerusalem artichoke ( Helianthus tuberosus L.) leaves and their quantitative analysis - Ming-Yang Wang; Zhi-Li Ma; Cheng-Li He; Xiao-Yan Yuan (Natural Product Research, 2022)

Sweet tea ( Lithocarpus polystachyus rehd.) as a new natural source of bioactive dihydrochalcones with multiple health benefits - Ao Shang; Hong-Yan Liu; Min Luo; Yu Xia; Xiao Yang; Hang-Yu Li; Ding-Tao Wu; Quancai Sun; Fang Geng; Ren-You Gan (Critical Reviews in Food Science and Nutrition, 2022)

Neutrophil Extracellular Traps may be a Potential Target for Treating Early Brain Injury in Subarachnoid Hemorrhage - Hanhai Zeng; Xiongjie Fu; Jing Cai; Chenjun Sun; Mengyan Yu; Yucong Peng; Jianfeng Zhuang; Jingyin Chen; Huaijun Chen; Qian Yu; Chaoran Xu; Hang Zhou; et al. (Translational Stroke Research, 2022)

Electroacupuncture Enhance Therapeutic Efficacy of Mesenchymal Stem Cells Transplantation in Rats With Intracerebral Hemorrhage - Li Deng; Ling Zhou; Yan Zhu; Guangbi Fan; Huajun Tang; Yujie Zheng; Xiaoqing Gao; Kan Guo; Peng Zhou; Chaoxian Yang (Stem Cell Reviews and Reports, 2022)

Shifting from homogeneous to heterogeneous surfaces in estimating terrestrial evapotranspiration: Review and perspectives - Yuanbo Liu; Guoyu Qiu; Hongsheng Zhang; Yonghui Yang; Yinsheng Zhang; Quan Wang; Wenzhi Zhao; Li Jia; Xibin Ji; Yujiu Xiong; Chunhua Yan; Ning Ma; et al. (Science China Earth Sciences, 2022)

Development of molecular markers based on LTR retrotransposon in the Cleistogenes songorica genome - Tiantian Ma; Xingyi Wei; Yufei Zhang; Jie Li; Fan Wu; Qi Yan; Zhuanzhuan Yan; Zhengshe Zhang; Gisele Kanzana; Yufeng Zhao; Yingbo Yang; Jiyu Zhang (Journal of Applied Genetics, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Investigation of indole biodegradation by Cupriavidus sp. strain IDO with emphases on downstream biotransformation and indigo production - Chunxiao Dai; Fang Ma; Qiao Ma; Jing Yang; Yan Li; Bingyu Yang; Yuanyuan Qu (Environmental Science and Pollution Research, 2022)

Selenium Attenuates S. aureus-Induced Inflammation by Regulation TLR2 Signaling Pathway and NLRP3 Inflammasome in RAW 264.7 Macrophages - Ming-Ji Wei; Zhen-Nan Wang; Yan Yang; Shu-Jiu Zhang; He Tang; Hui Li; Chong-Liang Bi (Biological Trace Element Research, 2022)

Methods for the construction of DEMs of artificial slopes considering morphological features and semantic information - Yan Xu; Ming-wei Zhao; Jie Lu; Chun Wang; Ling Jiang; Can-can Yang; Xiao-li Huang (Journal of Mountain Science, 2022)

Responses and feedback of litter properties and soil mesofauna to herbaceous plants expansion into the alpine tundra on Changbai Mountain, China - Ying-jie Zhang; Ying-hua Jin; Jia-wei Xu; Hong-shi He; Yan Tao; Zhi-peng Yang; Jing Zhao; Yin-xia Diao; Chen-hui Sun; Mai-He Li (Journal of Mountain Science, 2022)

Genetic Polymorphism of 24 Autosomal STR in the Population of Rwanda - Gasana Paul; JunLin Liu; Pan Ma; Abiy Wendifraw Assefa; Jingsi Yang; Shaoqing Li; DongKe Fu; Yan Liu; Rutayisire Gad; Kamuhangire Edward; Shengbin Li; Bao Zhang; et al. (Biochemical Genetics, 2022)

Geographic latitude and human height - Statistical analysis and case studies from China - Guoguang Lu; Yi Hu; Zhihui Yang; Yan Zhang; Shengxu Lu; Siyuan Gong; Tingting Li; Yijie Shen; Sihan Zhang; Hanya Zhuang (Arabian Journal of Geosciences, 2022)
Based on Chinese General Social Survey(CGSS) data, this paper selects ten variables, including height, gender, household registration, and age. Through the statistical analysis of 57,574 survey samples, this study finds that the average height of China’s population has increased by more than 10 cm in the past 100 years. Among the findings, the data indicate the average height of men born after the 1990s is 11 cm taller than that of men born after the 1920s, which has now reached 173 cm, and that the height of women is 10.93 cm taller, averaging 163 cm. The average height of the Chinese population reflects significant differences in gender, region or province, urbanity and rurality, and nationality, among other variables. The average height of men and women gradually increases with the increase of geographical latitude. Some economically developed southern provinces approach the average height of the North. This paper predicts that the average height of the newborn population will continue to have inertial growth in the next 20 years, and the newborn male population will reach the World Health Organization’s ideal height standard of 176.5 cm by 2030. The analysis suggests that geographic latitude and heredity are the determinants of body development. Geographical latitude difference is a super-variable for human mitochondria to regulate the proportion of heat outflow and ATP transformation. Historically, the population living in high-latitude areas of China migrates to economically developed low-latitude provinces such as Shanghai, Jiangsu, Zhejiang, and Guangdong, which is the main reason why the per capita height in these areas is significantly taller than that in other southern provinces.

Numerical investigation of the control factors driving Zhe-Min Coastal Current - Yang Zhang; Fei Chai; Joseph Zhang; Yang Ding; Min Bao; Yunwei Yan; Hong Li; Wei Yu; Liang Chang (Acta Oceanologica Sinica, 2022)

Secondary metabolites isolated from Agrimonia pilosa Ledeb. - Hong-Rui Li; Yu-Kui Li; Jian Xiao; Cui Yang; Meng-Yuan Jiang; Kai Tian; Wei Wang; Yan-Hong Li; Xiang-Zhong Huang (Natural Product Research, 2022)

Seven new glycosides from the leaves of Datura metel L. - Jin-Yan Tan; Yan Liu; Yan-Gang Cheng; Yan-Ping Sun; Xiao-Mao Li; Wei Guan; Juan Pan; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Myrothecol A, a new alkylresorcinol with cytotoxicity from Myrothecium sp. - Zhen-Hua Li; Hui-Yuan Yang; Wen-Ting Zhu; Dong-Dong Jing; Shi-Neng Li; Peng-Ke Yan (Natural Product Research, 2022)

Genetic dissection of quantitative trait loci for grain size and weight by high-resolution genetic mapping in bread wheat (Triticum aestivum L.) - Tao Li; Guangbing Deng; Yan Su; Zhao Yang; Yanyan Tang; Jinhui Wang; Juanyu Zhang; Xvebing Qiu; Xi Pu; Wuyun Yang; Jun Li; Zehou Liu; et al. (Theoretical and Applied Genetics, 2022)

Taxonomical and functional bacterial community selection in the rhizosphere of the rice genotypes with different nitrogen use efficiencies - Wei Chen; Yan Gao; Jie Yang; Fangjun Fan; Weiguo Zhang; Jiangye Li; Cong Zhou; Gaoling Shi; Fei Tong; Guangping Fan (Plant and Soil, 2022)

Genetic diversity of Lathyrus sp collected from different geographical regions - Md. Mosiur Rahman; Md. Ruhul Quddus; Md. Omar Ali; Rong Liu; Mengwei Li; Xin Yan; Guan Li; Yishan Ji; Md. Monoar Hossain; Chenyu Wang; Ashutosh Sarker; Tao Yang; et al. (Molecular Biology Reports, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

Blood transcriptome analysis revealed the immune changes and immunological adaptation of wildness training giant pandas - Miao Yang; Yan Huang; Honglin Wu; Caiwu Li; Shanshan Ling; Jie Sun; Haibo Shen; Bisong Yue; Xiuyue Zhang (Molecular Genetics and Genomics, 2022)

Evaluation of EpCAM-specific exosomal lncRNAs as potential diagnostic biomarkers for lung cancer using droplet digital PCR - Xintong Shen; Yifeng Yang; Yinfeng Chen; Chengwei Zhou; Xiaodong Zhao; Nan Li; Chengtao Lou; Ying Huang; Dongmei Tian; Yan Shen; Xiaodan Meng (Journal of Molecular Medicine, 2022)

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells - Xiang-xing Zhu; Jia-sheng Pan; Tao Lin; Ye-cheng Yang; Qiu-yan Huang; Shuai-peng Yang; Zi-xiao Qu; Zi-sheng Lin; Jian-cong Wen; Ai-fen Yan; Juan Feng; Lian Liu; et al. (Biotechnology Letters, 2022)

Dysregulated lncRNA and mRNA may promote the progression of ischemic stroke via immune and inflammatory pathways: results from RNA sequencing and bioinformatics analysis - Yingshuang Wang; Feifei Feng; Pingping Zheng; Lijuan Wang; Yanjun Wang; Yaogai Lv; Li Shen; Kexin Li; Tianyu Feng; Yang Chen; Zhigang Liu; Yan Yao (Genes & Genomics, 2022)

Identification of MicroRNAs as potential biomarkers for detecting ischemic stroke - Kexin Li; Li Shen; Pingping Zheng; Yanjun Wang; Lijuan Wang; Xiaoli Meng; Yaogai Lv; Zhiqiang Xue; Xin Guo; Anning Zhang; Pan Pan; Chunli Bi; et al. (Genes & Genomics, 2022)

Williamsia soli sp. nov., an actinobacterium isolated from soil at a thermal power plant in Yantai, China - Ming-Jing Zhang; Xue-Han Li; Li-Yang Peng; Shuai-Ting Yun; Zhuo-Cheng Liu; Yan-Xia Zhou (Archives of Microbiology, 2022)

Azospirillum tabaci sp. nov., a bacterium isolated from rhizosphere soil of Nicotiana tabacum L - Yan-Qing Duan; Xing-Kui Zhou; Neeli Habib; Shi-Qiang Gao; Li-Min Dong; Xiao-Fei Liu; Yang-Mei Shi; Wen-Jun Li; Gang Du (Archives of Microbiology, 2022)

Study on nanopore structure of soil and quantitative characterization based on mercury intrusion, liquid nitrogen adsorption, CO2 adsorption, and SEM - Xiangchun Li; Mengya Wang; Shuang Zhang; Wenyu Yan; Dengyu Xu; Yi Li; Yukun Fu; Chunli Yang; Lei Xie; Weidong Lu (Arabian Journal of Geosciences, 2022)

Hydrocarbon generation history in the Chagan Depression, Inner Mongolia, northern China: constraints of hydrocarbon generation kinetics and thermal history - Meihua Yang; Yinhui Zuo; Kangnan Yan; Yongshui Zhou; Xuejun Wang; Changchun Li; Ziyun Zheng (Arabian Journal of Geosciences, 2022)

Kangiella shandongensis sp. nov., a novel species isolated from saltern in Yantai, China - Li-Yang Peng; Rui Yin; Shu-Kun Gao; Hui-Ning Jiang; Xiao-Xiao Liu; Yu Ma; Yan-Xia Zhou (Antonie van Leeuwenhoek, 2022)

Two new bioactive polyphenols from the soft coral-derived fungus Talaromyces sp. SCSIO 041201 - Ji-xing Li; Xin-xin Lei; Yan-hong Tan; Yong-hong Liu; Bin Yang; Yun-qiu Li (Natural Product Research, 2021)

Comparative Transcriptome Analysis of Female and Male Fine-Patterned Puffer: Identification of Candidate Genes Associated with Growth and Sex Differentiation - Binbin Shan; Yan Liu; Changping Yang; Yuan Li; Liangming Wang; Dianrong Sun (Fishes, 2021)
Sexual growth dimorphism is a common phenomenon in teleost fish. However, the mechanism of this complex phenomenon remains unclear. The fine-patterned puffer (Takifugu poecilonotus; Temminck and Schlegel, 1850) exhibits female-biased sexual size dimorphism similar to other pufferfish. In this study, the transcriptomes of female and male T.poecilonotus were sequenced, 285.95 million raw read pairs were generated from sequence libraries. After identification and assembly, a total of 149,814 nonredundant unigenes were obtained with an N50 length of 3538 bp. Of these candidates, 122,719 unigenes (81.91% of the total) were successfully annotated with multiple public databases. The comparison analysis revealed 10,385 unigenes (2034 in females and 8351 in males) were differentially expressed between different sexes of T.poecilonotus. Then, we identified many candidate growth- and sex-related genes, including Dmrt1, Sox3, Spatas, Prl/Prlr, fabps, Ghr, and Igf1r. In addition to these well-known genes, Fabp4 was identified for the first time in fish. Furthermore, 68,281 simple sequence repeats (SSRs) loci were screened and identified in the transcriptome sequence of T.poecilonotus. The results of our study could provide valuable information on growth- and sex-associated genes and facilitate further exploration of the molecular mechanism of sexual growth dimorphism.

Species Composition and Assemblages of Ichthyoplankton in Sansha Bay, Fujian Province, China - Yan Jiang; Bai-an Lin; Hao-yang He; Guang-mao Ding; Li-ting Yan; Ge Zhang; Min Liu; Lian-ming Zheng (Frontiers in Marine Science, 2021)
Sansha Bay (26.40−27.00°N, 119.50−120.20°E) is a typical semi-enclosed bay, located in northern Fujian Province, China, and adjacent to the East China Sea. The ichthyoplankton species composition and assemblage structure were investigated based on monthly sampling at 25 stations in April−September 2019, covering the important spring and summer spawning seasons in the region. Sampling was conducted in the first 3−5 days of the full moon or new moon phases using a standard plankton net through horizontal and vertical tows during daytime. In total, 25,819 ichthyoplankton samples were collected, of which 25,449 samples (i.e., 24,757 eggs and 692 larvae) were from horizontal tows. For horizontal tow samples, the ichthyoplankton were classified into 58 taxa in 15 orders and 23 families with a combination of external morphology and DNA barcoding analyses, from pelagic to demersal and benthic species. The dominant order was the Gobiiformes, including 23 species (39.7% of all species). The dominant taxa, in terms of relative abundance and frequency of occurrence, consisted of commercially important fishes, such as Setipinna tenuifilis (Valenciennes, 1848) (Engraulidae), Epinephelus akaara (Temminck and Schlegel, 1842) (Serraenidae), Collichthys lucidus (Richardson, 1844), Nibea albiflora (Richardson, 1846) (Sciaenidae), Acanthopagrus schlegelii (Bleeker, 1854), and Pagrus major (Temminck and Schlegel, 1843) (Sparidae), accounting for 78.9% of the horizontal tow samples. Low-valued and small-sized fishes, such as Stolephorus commersonnii Lacepède, 1803 (Engraulidae), Solea ovata Richardson, 1846 (Soleidae), Nuchequula nuchalis (Temminck and Schlegel, 1845), and Photopectoralis bindus (Valenciennes, 1835) (Leiognathidae), were also dominant species, accounting for 11.4% of the horizontal tow samples. The ichthyoplankton assemblage was categorized into five different temporal assemblages based on the cluster and nonmetric multidimensional scaling analysis, namely, April, May, June, July, and August−September (ANOSIM, Global R = 0.656, p < 0.01) with the highest density and richness of ichthyoplankton occurred in May. The spatial distribution pattern showed that the high density (ind./m 3 ) of ichthyoplankton occurred mainly in S12–S25 in Guanjingyang and along the Dongchong Peninsula coastline into Dongwuyang, while low density occurred mainly in S01–S11 in the northwest waters of Sandu Island (ANOVA, F = 8.270, p < 0.05). Temperature, salinity, and chlorophyll a were key factors structuring the ichthyoplankton assemblages in Sansha Bay. In addition, this study revealed the changes of the ichthyoplankton composition, density, and spatial distribution in Sansha Bay over the past three decades.

Investigation of factors influencing the release of chloropropanols (3-MCPD and 1,3-DCP) from food contact paper - Huai-ning Zhong; Ying Zeng; Dao-yuan Yang; Ze-chun Wu; Dan Li; Hai-xia Sui; Jie Gao; Yan-fen Chen; Ce-Hui Mo (Food Additives & Contaminants: Part A, 2021)

Genomic Analysis of the Principal Members of Antioxidant Enzymes in Simulated Stresses Response and Postharvest Physiological Deterioration in Cassava - Sang Shang; Yuqi Tang; Jing Dai; Chunlai Wu; Yan Yan; Weiwei Tie; Meiying Li; Jinghao Yang; Jian Zeng; Mingjie Chen; Wei Hu (Tropical Plant Biology, 2021)

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2021)

Quantitative proteomic and lipidomics analyses of high oil content GmDGAT1-2 transgenic soybean illustrate the regulatory mechanism of lipoxygenase and oleosin - Yang Xu; Fan Yan; Yajing Liu; Ying Wang; Han Gao; Shihui Zhao; Youcheng Zhu; Qingyu Wang; Jingwen Li (Plant Cell Reports, 2021)

Hydrogen Sulfide Maintains Good Nutrition and Delays Postharvest Senescence in Postharvest Tomato Fruits by Regulating Antioxidative Metabolism - Ting-Ying Zhong; Gai-Fang Yao; Sha-Sha Wang; Ting-Ting Li; Ke-Ke Sun; Jun Tang; Zhong-Qin Huang; Feng Yang; Yan-Hong Li; Xiao-Yan Chen; Lan-Ying Hu; Hua Zhang; et al. (Journal of Plant Growth Regulation, 2021)

c-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3β Survival Pathway - Cong Yan; Hongwei Yu; Yao Liu; Pei Wu; Chunlei Wang; Hongbo Zhao; Kongbin Yang; Qi Shao; Yingqiang Zhong; Wenyang Zhao; Jingwei Li; Nan Liu; et al. (Journal of Molecular Neuroscience, 2021)

Antimicrobial Natural Products Produced by Soil-Derived Fungus Penicillium cremeogriseum W1-1 - Xu-Yan Sang; Zhao-Jie Wang; Ya-Bin Yang; Yong-Liang Wang; Mei-Ling Xiang; Dou-Ying Zhu; Ying Zhou; Xiao-Dong Luo; Li-Xing Zhao (Indian Journal of Microbiology, 2021)

Distinct phylogeographic structures and evolutionary histories of wild medicinal Salvia miltiorrhiza Bunge plant populations in the mountains of Central China - Xiaoguo Wang; Tao Ma; Ying Yun; Yan Li; Jing Zhang; Hongyan Liang; Xitian Yang (Genetic Resources and Crop Evolution, 2021)

Energy structure, digital economy, and carbon emissions: evidence from China - Yan Li; Xiaodong Yang; Qiying Ran; Haitao Wu; Muhammad Irfan; Munir Ahmad (Environmental Science and Pollution Research, 2021)

A comprehensive analysis of TDO2 expression in immune cells and characterization of immune cell phenotype in TDO2 knockout mice - Susu Li; Siyu Li; Yingjie Zhao; Bingjie Zhang; Xinwei Wang; Xuezhi Yang; Yueye Wang; Chengyan Jia; Yan Chang; Wei Wei (Transgenic Research, 2021)

Paleoenvironment controls on organic matter accumulation in transitional shales from the eastern Ordos Basin, China - Jianwei Lv; Songhang Zhang; Ning Yang; Chunbo Fu; Xinlu Yan; Yang Li (Frontiers of Earth Science, 2021)

Application of lipidomics strategy to explore aging-related biomarkers and potential anti-aging mechanisms of ginseng - Shenshen Yang; Yaqian Dong; Yuechen Liu; Xingxu Yan; Guijiang Sun; Guoxiang Jia; Xiaokai Li; Hui Liu; Haihua Su; Yubo Li (Biogerontology, 2021)

Identification and Expression Analyses of the Special 14–3-3 Gene Family in Papaya and its Involvement in Fruit Development, Ripening, and Abiotic Stress Responses - Meiying Li; Licheng Ren; Zhi Zou; Wei Hu; Susheng Xiao; Xiaoliang Yang; Zehong Ding; Yan Yan; Weiwei Tie; Jinghao Yang; Anping Guo (Biochemical Genetics, 2021)

The first third-generation HIV-1 circulating recombinant form (CRF114_0155) identified in central China - Yang Li; Yan Zhang; Hongye Wang; Long Liu; Hui Chen; Shuanhu Zhang; Wenying Wu; Rongge Yang (Archives of Virology, 2021)

Immune response of silver pomfret ( Pampus argenteus ) to Amyloodinium ocellatum infection - Youyi Zhang; Jiabao Hu; Yaya Li; Man Zhang; Kimran Jean Jacques; Weiwei Gu; Yibo Sun; Jiachu Sun; Yang Yang; Shanliang Xu; Yajun Wang; Xiaojun Yan (Journal of Fish Diseases, 2021)
Amyloodinium ocellatum (AO) infection in silver pomfret ( Pampus argenteus ) causes extensive mortality. Insufficient information exists on the molecular immune response of silver pomfret to AO infestation, so herein we simulated the process of silver pomfret being infected by AO. Translucent trophosomes were observed on the gills of AO‐infected fish. Transcriptome profiling was performed to investigate the effects of AO infection on the gill, kidney complex and spleen. Overall, 404,412,298 clean reads were obtained, assembling into 96,341 unigenes, which were annotated against public databases. In total, 2730 differentially expressed genes were detected, and few energy‐ and immune‐related genes were further assessed using RT‐qPCR. Moreover, activities of three immune‐related (SOD, AKP and ACP) and three energy‐related (PKM, LDH and GCK) enzymes were determined. AO infection activated the immune system and increased interleukin‐1 beta and immunoglobulin M heavy chain levels. Besides, the PPAR signalling pathway was highly enriched, which played a role in improving immunity and maintaining homeostasis. AO infection also caused dyspnoea, leading to extensive lactic acid accumulation, potentially contributing towards a strong immune response in the host. Our data improved our understanding regarding the immune response mechanisms through which fish coped with parasitic infections and may help prevent high fish mortality in aquaculture.

The Effect of Oxidized Fish Oil on the Spleen Index, Antioxidant Activity, Histology and Transcriptome in Juvenile Hybrid Grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) - Shuisheng Long; Zhihao Li; Xiaohui Dong; Xiaobo Yan; Hao Liu; Beiping Tan; Shuang Zhang; Simiao Pan; Tao Li; Xiangxiang Suo; Yuanzhi Yang (Frontiers in Marine Science, 2021)
The spleen is an important organ in the immune function of fish, and it is also important for hematogenesis and antibody and granulocyte production. However, the effect of oxidized fish oil on the spleen of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus ) is unknown. In this study, hybrid groupers were fed with oxidized fish oil and the spleen index, antioxidant ability, histology and transcriptome were investigated. Oxidized fish oil did not affect the spleen index. Levels of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and malondialdehyde (MDA) in the spleen were significantly increased as the amount of oxidized fish oil in the diet increased, but the vitamin E concentration was significantly decreased. The morphological organization of the spleen was damaged with increased oxidative stress. And the spleen reacted to oxidative stress by platelet activation, FOXO and notch signaling pathways, which involved amyloid beta precursor protein binding family B member 1 interacting protein (APBB1IP) gene, glucose-6-phosphatase (G6PC) gene, histone acetyltransferase p300 (EP300) gene, insulin gene and notch 2 gene. In conclusion, the oxidized fish oil caused oxidative stress and damaged its structure. Additionally, oxidized fish oil changed the transcription profile of the spleen.

Cytotoxic triterpenoid glycosides from leaves of Cyclocarya paliurus - Hui-Hui Sun; Wen-Yan Lv; Jie Tan; Yu-Cheng Tang; Hui Zhu; Jian-Bo Qu; Jing Li; Jian-Ping Wu; Xi-Wen Chang; Zhi-Chun Yang; Wen-Xuan Wang; Zu-Hui Chen; et al. (Natural Product Research, 2021)

Three new diterpenoids from Euphorbia peplus - Yan-Ni Chen; Qing-Yun Lu; Dong-Mei Li; Ying-Yao Li; Xue-Xue Pu; Bo-Ting Li; Xiao-Han Tang; Hong-Yu Tang; Shuai Liu; Lei Yang; Yu Zhang; Ying-Tong Di; et al. (Natural Product Research, 2021)

Two new alkaloids from the sepals of Solanum melongena L - Dong-Ying Zhao; Yan Liu; Xin Yin; Xiao-Mao Li; Juan Pan; Wei Guan; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2021)

Quantitative Analysis of Eco-economic Benefits of Urban Reclaimed Water Greening Based on Emergy Theory - Cuimei Lv; Yifan He; Wenge Zhang; Changkuan Gu; Yang Li; Denghua Yan (Water Resources Management, 2021)

Identification and fine genetic mapping of the golden pod gene (pv-ye) from the snap bean (Phaseolus vulgaris L.) - Xiaoxu Yang; Chang Liu; Yanmei Li; Zhishan Yan; Dajun Liu; Guojun Feng (Theoretical and Applied Genetics, 2021)

Fine mapping and validation of a major QTL for grain weight on chromosome 5B in bread wheat - Dehui Zhao; Li Yang; Dan Liu; Jianqi Zeng; Shuanghe Cao; Xianchun Xia; Jun Yan; Xiyue Song; Zhonghu He; Yong Zhang (Theoretical and Applied Genetics, 2021)

Identification and validation of two major QTLs for spike compactness and length in bread wheat (Triticum aestivum L.) showing pleiotropic effects on yield-related traits - Tao Li; Guangbing Deng; Yan Su; Zhao Yang; Yanyan Tang; Jinhui Wang; Xvebing Qiu; Xi Pu; Jun Li; Zehou Liu; Haili Zhang; Junjun Liang; et al. (Theoretical and Applied Genetics, 2021)

Molecular cloning of myosin chaperone uncoordinate-45B (UNC-45B) and its heat stress response in the muscle of Pacific bluefin tuna Thunnus orientalis - Yi-Li Gao; Asami Yoshida; Jin-Yang Liu; Uno Yamashita; Yan-Rong Jiang; Xiao-Mi Sun; Kazuya Shirota; Yasuhiko Shiina; Kiyoshi Osatomi (Fisheries Science, 2021)

Characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with idiopathic membranous nephropathy - Lie Yang; Peng Xia; Yangzhong Zhou; Quexuan Cui; Gang Chen; Ke Zheng; Yan Qin; Xuemei Li (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Comparative activities of sitafloxacin against recent clinical isolates in hospitals across China - Shi Wu; Yang Yang; Yan Guo; Dandan Yin; Yonggui Zheng; Renru Han; Li Ding; Demei Zhu; Fupin Hu (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Melatonin antagonizes ozone-exacerbated asthma by inhibiting the TRPV1 channel and stabilizing the Nrf2 pathway - Yushan Chen; Xiaoyu Wu; Xu Yang; Xudong Liu; Yan Zeng; Jinquan Li (Environmental Science and Pollution Research, 2021)

Comparative genomic analysis of Mycoplasma anatis strains - Qi Zhou; Kaijie Mai; Dehong Yang; Junfa Liu; Zhuanqiang Yan; Cuifen Luo; Yangtong Tan; Sheng Cao; Qingfeng Zhou; Li Chen; Feng Chen (Genes & Genomics, 2021)

The identification of fish eggs of two species, the ovate sole Solea ovata and black porgy Acanthopagrus schlegelii - Yan‐jing Zheng; Xiu‐qin Li; Zhen‐xiong Yang; Wei‐xu Cai; Quan‐sheng Lou; Wei Tao (Journal of Fish Biology, 2021)
Fish eggs of the ovate sole Solea ovata and black porgy Acanthopagrus schlegelii were identified through DNA barcoding of cytochrome c oxidase subunit I (COX1). Visual taxonomic features were achieved, and photographs of the eggs of both species at different developmental stages were reported for the first time. In addition, the dissolution of oil globules caused by ethanol as egg fixatives was observed. This result showed the importance of using formalin as egg fixatives in the case of morphometric analysis and the necessity of combining molecular and visual taxonomic method for morphological study.

Cytochalasins from endophytic Diaporthe sp. GDG-118 - Xishan Huang; Dexiong Zhou; Yan Liang; Xiaobo Liu; Fei Cao; Yuyue Qin; Tuxiang Mo; Zhaolong Xu; Jun Li; Ruiyun Yang (Natural Product Research, 2021)

Master regulator NtrC controls the utilization of alternative nitrogen sources in Pseudomonas stutzeri A1501 - Zhimin Yang; Qin Li; Yongliang Yan; Xiubin Ke; Yueyue Han; Shaoyu Wu; Fanyang Lv; Yahui Shao; Shanshan Jiang; Min Lin; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2021)
Pseudomonas stutzeri A1501 is a model strain used to study associative nitrogen fixation, and it possesses the nitrogen regulatory NtrC protein in the core genome. Nitrogen sources represent one of the important factors affecting the efficiency of biological nitrogen fixation in the natural environment. However, the regulation of NtrC during nitrogen metabolism in P. stutzeri A1501 has not been clarified. In this work, a phenotypic analysis of the ntrC mutant characterized the roles of NtrC in nitrogen metabolism and the oxidative stress response of P. stutzeri A1501. To systematically identify NtrC-controlled gene expression, RNA-seq was performed to further analyse the gene expression differences between the wild-type strain and the ∆ ntrC mutant under nitrogen fixation conditions. A total of 1431 genes were found to be significantly altered by ntrC deletion, among which 147 associative genes had NtrC-binding sites, and the pathways for nitrogen fixation regulation, nitrogenous compound acquisition and catabolism and nitrate assimilation were discussed. Furthermore, the oxidative stress-related gene ( katB ), which was upregulated by ntrC deletion, was suggested to be a potential target gene of NtrC, thus highlighting the importance of NtrC in nitrogenase protection against oxygen damage. Based on these findings, we propose that NtrC is a high-ranking element in the regulatory network of P. stutzeri A1501 that controls a variety of nitrogen metabolic and oxidative stress responsive traits required for adaptation to complex rhizosphere environments.

Genetic and molecular characterization of determinant of six-rowed spike of barley carrying vrs1.a4 - Jin-Hui Wang; Zhen-Mei Xu; Xue-Bing Qiu; Li-Lan Li; Shui-Yang Yu; Tao Li; Yan-Yan Tang; Xi Pu; Juan-Yu Zhang; Hai-Li Zhang; Jun-Jun Liang; Ya-Wei Tang; et al. (Theoretical and Applied Genetics, 2021)

Development and application of the Faba_bean_130K targeted next-generation sequencing SNP genotyping platform based on transcriptome sequencing - Chenyu Wang; Rong Liu; Yujiao Liu; Wanwei Hou; Xuejun Wang; Yamei Miao; Yuhua He; Yu Ma; Guan Li; Dong Wang; Yishan Ji; Hongyan Zhang; et al. (Theoretical and Applied Genetics, 2021)

Single cell transcriptomic analysis identifies novel vascular smooth muscle subsets under high hydrostatic pressure - Zhenzhen Chen; Haizeng Zhang; Yingnan Bai; Changting Cui; Shuangyue Li; Wenjie Wang; Yue Deng; Qiannan Gao; Lu Wang; Wei Qi; Lijun Zhang; Yan Yang; et al. (Science China Life Sciences, 2021)

Screening and identification of salt-tolerance genes in Sophora alopecuroides and functional verification of SaAQP - Youcheng Zhu; Qingyu Wang; Wenyun Guo; Ziwei Gao; Ying Wang; Yang Xu; Yajing Liu; Zhipeng Ma; Fan Yan; Jingwen Li (Planta, 2021)

Treadmill Exercise Relieves Chronic Restraint Stress-induced Cognitive Impairments in Mice Via Activating Protein Phosphatase 2A - Wenjing Zhang; Haining Ou; Borui Zhang; Meifeng Zheng; Lan Yan; Yang Chen; Kwok-Fai So; Li Zhang (Neuroscience Bulletin, 2021)

Pharmacological Activation of RXR-α Promotes Hematoma Absorption via a PPAR-γ-dependent Pathway After Intracerebral Hemorrhage - Chaoran Xu; Huaijun Chen; Shengjun Zhou; Chenjun Sun; Xiaolong Xia; Yucong Peng; Jianfeng Zhuang; Xiongjie Fu; Hanhai Zeng; Hang Zhou; Yang Cao; Qian Yu; et al. (Neuroscience Bulletin, 2021)

Gut-Derived Exosomes Mediate Memory Impairment After Intestinal Ischemia/Reperfusion via Activating Microglia - Xiao-Dong Chen; Jin Zhao; Xiao Yang; Bo-Wei Zhou; Zhengzheng Yan; Wei-Feng Liu; Cai Li; Ke-Xuan Liu (Molecular Neurobiology, 2021)

Recent progress of oridonin and its derivatives for cancer therapy and drug resistance - Yong-Feng Guan; Xiu-Juan Liu; Xiao-Jing Pang; Wen-Bo Liu; Guang -Xi Yu; Yin -Ru Li; Yan-Bing Zhang; Jian Song; Sai-Yang Zhang (Medicinal Chemistry Research, 2021)

Study on the Relationship between the miRNA-centered ceRNA Regulatory Network and Fatigue - Xingzhe Yang; Feng Li; Jie Ma; Yan Liu; Xuejiao Wang; Ruochong Wang; Yifei Zhang; Wei Zhang; Qingyun He; Dandan Song; Jiaojiao Yu (Journal of Molecular Neuroscience, 2021)
In recent years, the incidence of fatigue has been increasing, and the effective prevention and treatment of fatigue has become an urgent problem. As a result, the genetic research of fatigue has become a hot spot. Transcriptome-level regulation is the key link in the gene regulatory network. The transcriptome includes messenger RNAs (mRNAs) and noncoding RNAs (ncRNAs). MRNAs are common research targets in gene expression profiling. Noncoding RNAs, including miRNAs, lncRNAs, circRNAs and so on, have been developed rapidly. Studies have shown that miRNAs are closely related to the occurrence and development of fatigue. MiRNAs can regulate the immune inflammatory reaction in the central nervous system (CNS), regulate the transmission of nerve impulses and gene expression, regulate brain development and brain function, and participate in the occurrence and development of fatigue by regulating mitochondrial function and energy metabolism. LncRNAs can regulate dopaminergic neurons to participate in the occurrence and development of fatigue. This has certain value in the diagnosis of chronic fatigue syndrome (CFS). CircRNAs can participate in the occurrence and development of fatigue by regulating the NF-κB pathway, TNF-α and IL-1β. The ceRNA hypothesis posits that in addition to the function of miRNAs in unidirectional regulation, mRNAs, lncRNAs and circRNAs can regulate gene expression by competitive binding with miRNAs, forming a ceRNA regulatory network with miRNAs. Therefore, we suggest that the miRNA-centered ceRNA regulatory network is closely related to fatigue. At present, there are few studies on fatigue-related ncRNA genes, and most of these limited studies are on miRNAs in ncRNAs. However, there are a few studies on the relationship between lncRNAs, cirRNAs and fatigue. Less research is available on the pathogenesis of fatigue based on the ceRNA regulatory network. Therefore, exploring the complex mechanism of fatigue based on the ceRNA regulatory network is of great significance. In this review, we summarize the relationship between miRNAs, lncRNAs and circRNAs in ncRNAs and fatigue, and focus on exploring the regulatory role of the miRNA-centered ceRNA regulatory network in the occurrence and development of fatigue, in order to gain a comprehensive, in-depth and new understanding of the essence of the fatigue gene regulatory network.

Study on the Correlation Between NF-κB and Central Fatigue - Xingzhe Yang; Feng Li; Yan Liu; Danxi Li; Jie Li (Journal of Molecular Neuroscience, 2021)
In recent years, the World Health Organization (WHO) has included fatigue as a major risk factor for human life and health. The incidence rate of fatigue is high. In Europe and America, nearly 1/3 of the population is suffering from fatigue. Due to the acceleration of modern people’s life rhythm and the increase of work pressure, more and more attention has been paid to central fatigue. The activation of NF-κB is related to central fatigue, which has been paid little attention by previous studies. At the same time, previous studies have mostly focused on the immune regulation function of NF-κB, while the NF-κB pathway plays an equally important role in regulating nerve function. NF-κB can participate in the occurrence and development of central fatigue by mediating immune inflammatory response, regulating central excitability and inhibitory transmitters, regulating synaptic plasticity and regulating central nervous system (CNS) functional genes. In addition to neuroprotective effects, NF-κB also has nerve damage effects, which is also closely related to the occurrence and development of central fatigue. In this review, we focus on the relationship between NF-κB pathway and central fatigue and further explore the biological mechanism of central fatigue. At the same time, the clinical application and potential of typical NF-κB inhibitors in the treatment of fatigue were analyzed to provide reference for the clinical treatment of central fatigue.

Seasonal variations in water flux compositions controlled by leaf development: isotopic insights at the canopy–atmosphere interface - Pei Wang; Haitao Sun; Xiao-Yan Li; Xin Song; Xiaofan Yang; Xiuchen Wu; Xia Hu; Hongyun Yao; Jingjing Ma; Juanjuan Ma (International Journal of Biometeorology, 2021)

Mercury sources and physicochemical characteristics in ice, snow, and meltwater of the Laohugou Glacier Basin, China - Rukumesh Paudyal; Shichang Kang; Junming Guo; Lekhendra Tripathee; Chhatra Mani Sharma; Jie Huang; Yang Li; Fangping Yan; Kun Wang; Jizu Chen; Xiang Qin; Mika Sillanpaa (Environmental Science and Pollution Research, 2021)

Diversity, abundance, and distribution of anammox bacteria in shipping channel sediment of Hong Kong by analysis of DNA and RNA - Xiaowei Zhang; Han Meng; Yuchun Yang; Wensheng Lan; Weidong Wang; Paul K. S. Lam; Xiao-Yan Li; Ji-Dong Gu (Ecotoxicology, 2021)

Added value of kilometer-scale modeling over the third pole region: a CORDEX-CPTP pilot study - Xu Zhou; Kun Yang; Lin Ouyang; Yan Wang; Yaozhi Jiang; Xin Li; Deliang Chen; Andreas Prein (Climate Dynamics, 2021)

Impulsivity in heroin‐dependent individuals: structural and functional abnormalities within frontostriatal circuits - Shicong Wang; Min Zhang; Shuang Liu; Yan Xu; Ziqiang Shao; Longmao Chen; Jun Li; Wenhan Yang; Jun Liu; Kai Yuan (Brain Imaging and Behavior, 2021)

An Investigation of Toxic Metal Levels (Pb, Cd, Cr, As, Hg) in Dried Porphyra and Laminaria Collected from Coastal Cities, China - Yan Chen; Yong-tao Liu; Fu-hua Wang; Dian Wen; Hui Yang; Xiao-li Zhao (Biological Trace Element Research, 2021)

A new strategy combined HASM and classical interpolation methods for DEM construction in areas without sufficient terrain data - Jing Wang; Ming-wei Zhao; Ling Jiang; Can-can Yang; Xiao-li Huang; Yan Xu; Jie Lu (Journal of Mountain Science, 2021)

Raspberry (Rubus idaeus L.) NCED1 gene enhances high salinity and cold tolerance in Arabidopsis - Guohui Yang; Yuxiao Chen; Heng Yu; Hang Zhang; Deguo Han; Xiaoyu Guo; Enqing Yan; Hanyi Quan; Tiemei Li (In Vitro Cellular & Developmental Biology - Plant, 2021)

Dynamic process of rock avalanche and dynamic interaction between rock avalanche and hazard-bearing bodies - Zhong Fu Wang; Man He; Yan Wang; Jingzhuo Yang; Haoyuan Li (Arabian Journal of Geosciences, 2021)

The influence of Stokes drift on oil spills: Sanchi oil spill case - Yiqiu Yang; Yan Li; Juan Li; Jingui Liu; Zhiyi Gao; Kaixuan Guo; Han Yu (Acta Oceanologica Sinica, 2021)

Transcriptome Profiling Based on Different Time Points After Hatching Provides a Core Set of Gene Resource for Understanding Larval Immune Response Mechanisms Against Vibrio anguillarum Infection in Amphioctopus fangsiao - Xiaokai Bao; Yan Li; Jianbai Zhang; Xipan Chen; Xiaohui Xu; Yanwei Feng; Guohua Sun; Xiumei Liu; Bin Li; Weijun Wang; Zan Li; Jianmin Yang (Frontiers in Marine Science, 2021)
Immune defense systems are indispensable for living organisms. Within an immune network, problems with any given link can impact the normal life activities of an organism. Amphioctopus fangsiao is a cephalopod that exists widely throughout the world’s oceans. Because of its nervous system and locomotive organs, it has become increasingly studied in recent years. Vibrio anguillarum is one of the most common pathogenic bacteria in aquaculture organisms. It is highly infectious and can infect almost all aquaculture organisms. V. anguillarum infection can cause many adverse biological phenomena, including tissue bleeding. Study the immune response after V. anguillarum infection would help us to understand the molecular mechanisms of immune response in aquaculture organisms. In this research, we infected the primary incubation A. fangsiao with V. anguillarum for 24 h. We analyzed gene expression in A. fangsiao larvae via transcriptome profiles at 0, 4, 12, and 24 h after hatching, and 1,385, 734, and 6,109 differentially expressed genes (DEGs) were identified at these three time points. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were used to identify immune-related DEGs. Protein–protein interaction networks were constructed to examine interactions between immune-related genes. Twenty hub genes involved in multiple KEGG signaling pathways or with multiple protein–protein interaction relationships were identified, and their differential expression verified by quantitative RT-PCR. We first studied V. anguillarum infection of A. fangsiao larvae by means of protein–protein interaction networks. The results provide valuable genetic resources for understanding immunity in molluscan larvae. These data serve as a theoretical basis for the artificial breeding of A. fangsiao .

Genetic control of Fusarium head blight resistance in two Yangmai 158-derived recombinant inbred line populations - Haisheng Yan; Guoqiang Li; Jinxing Shi; ShunShun Tian; Xiaoqiu Zhang; Rui Cheng; Xin Wang; Yang Yuan; Shouyang Cao; Jiyang Zhou; Zhongxin Kong; Haiyan Jia; et al. (Theoretical and Applied Genetics, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Hidden diversity of powdery mildews belonging to the recently re-discovered genus Salmonomyces - Dan-Ni Jin; Levente Kiss; Susumu Takamatsu; Zhao-Yang Zhang; Maria Graciela Cabrera de Álvarez; Zhuang Li; Yu Li; Shu-Yan Liu (Mycological Progress, 2021)

Phelligridin D from Inonotus obliquus attenuates oxidative stress and accumulation of ECM in mesangial cells under high glucose via activating Nrf2 - Yan Li; Yang Zhou; Jing Wu; Jindong Li; Huankai Yao (Journal of Natural Medicines, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Neuroanatomical correlates of self-awareness of highly practiced visuomotor skills - Junjun Li; Zhenglong Lin; Ran Tao; Min Xu; Shihong Kong; Hong-Yan Bi; Yang Yang (Brain Structure and Function, 2021)

First report of leaf spots on Gentiana rhodantha caused by Pestalotiopsis trachicarpicola - Xiaoyong Zhang; Youlian Yang; Shujiang Li; Kai Yan; Xinran Li (Journal of General Plant Pathology, 2021)

Wogonin Accelerates Hematoma Clearance and Improves Neurological Outcome via the PPAR-γ Pathway After Intracerebral Hemorrhage - Jianfeng Zhuang; Yucong Peng; Chi Gu; Huihui Chen; Zheng Lin; Hang Zhou; Xiao Wu; Jianru Li; Xiaobo Yu; Yang Cao; Hanhai Zeng; Xiongjie Fu; et al. (Translational Stroke Research, 2021)

Identification and candidate gene mining of HvSS1, a novel qualitative locus on chromosome 6H, regulating the uppermost internode elongation in barley (Hordeum vulgare L.) - Xi Pu; Yanyan Tang; Meihao Zhang; Tao Li; Xvebing Qiu; Juanyu Zhang; Jinhui Wang; Lilan Li; Zhao Yang; Yan Su; Haili Zhang; Junjun Liang; et al. (Theoretical and Applied Genetics, 2021)

Inhibition of Ca2+-dependent protein kinase C rescues high calcium–induced pro-arrhythmogenic cardiac alternans in rabbit hearts - Pei-pei Zhang; Liangkun Hu; You-jia Tian; Zefu Zhang; Pei-hua Zhang; Yan-yan Yang; Shi-han Li; Jihua Ma (Pflügers Archiv - European Journal of Physiology, 2021)

Smad3 gene C-terminal phosphorylation site mutation exacerbates CCl4-induced hepatic fibrogenesis by promoting pSmad2L/C-mediated signaling transduction - Juan Yang; Yongfang Gong; Wenjing Xu; Lili Li; Zhenghao Shi; Qin Wang; Yinghao He; Chong Zhang; Chenchen Luo; Zhirui Fang; Yan Yang (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Quantifying rain, snow and glacier meltwater in river discharge during flood events in the Manas River Basin, China - Yan Liu; Lu Xinyu; Zhang Liancheng; Li Yang; Ji Chunrong; Wang Ni; Zhang Juan (Natural Hazards, 2021)

Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2 - Yan Wen; Zihao Su; Ziwu Wang; Lin Yang; Guoping Liu; Zicong Shang; Yangyang Duan; Heng Du; Zhenmeiyu Li; Yan You; Xiaosu Li; Zhengang Yang; et al. (Molecular Neurobiology, 2021)

Soil macropore networks derived from X-ray computed tomography in response to typical thaw slumps in Qinghai-Tibetan Plateau, China - Zhi-Guang Yang; Xia Hu; Xiao-Yan Li; Zhou Gao; Yun-Duo Zhao (Journal of Soils and Sediments, 2021)

Application of Plant Print Identification Technology in Salt-resistant Soybean Breeding - Yan Li; Xia Li; Zi-qi Chen; Ying Ma; Guang-yu Yang; Ying Zhang; Ming-chun Sun; Li-hong Zhang; Jin-meng Chu; Jing-mei Lu; Jun Zhu; Ji-hong You (Journal of Plant Growth Regulation, 2021)

Combination of Red and Blue Lights Improved the Growth and Development of Eggplant (Solanum melongena L.) Seedlings by Regulating Photosynthesis - Qinghua Di; Jing Li; Yufen Du; Min Wei; Qinghua Shi; Yan Li; Fengjuan Yang (Journal of Plant Growth Regulation, 2021)

Systemic acquired resistance plays a major role in bacterial blight resistance in a progeny of somatic hybrids of cultivated rice (Oryza sativa L.) and wild rice (Oryza meyeriana L.) - Rumeng Xu; Jie Zhou; Ersong Zheng; Yong Yang; Dongyue Li; Yang Chen; Chengqi Yan; Jianping Chen; Xuming Wang (Journal of Plant Diseases and Protection, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice - Ji-Xiao Zhu; Hai-Yan Yang; Wei-Qiong Hu; Jie Cheng; Yang Liu; Li-Tao Yi; Hong-Yu Cheng (Inflammopharmacology, 2021)

The preliminary evaluation of differential characteristics and factor evaluation of the microbial structure of rural household toilet excrement in China - Yi Gao; Houyu Li; Bo Yang; Xiaocheng Wei; Chunxue Zhang; Yan Xu; Xiangqun Zheng (Environmental Science and Pollution Research, 2021)

Abundance and mobility of metal(loid)s in reservoir sediments of Singe Tsangpo and Yarlung Tsangpo in Tibet, China: Implications for ecological risk - Zhenjie Zhao; Shehong Li; Lili Xue; Jie Liao; Jingjing Zhao; Mei Wu; Mingguo Wang; Qiang Yang; Jing Sun; Yan Zheng (Environmental Geochemistry and Health, 2021)

Flexible reconfiguration of functional brain networks as a potential neural mechanism of creativity - Junchao Li; Natasza Orlov; Zengjian Wang; Bingqing Jiao; Yibo Wang; Huawei Xu; Hui Yang; Yingying Huang; Yan Sun; Peng Zhang; Rengui Yu; Ming Liu; et al. (Brain Imaging and Behavior, 2021)

Mild encephalitis/encephalopathy with a reversible splenial lesion associated with respiratory syncytial virus infection in infants - Xue-Lin Li; Jinming Han; Zhong-Rui Yan; Bing-Wei Zhang; Hai-Yang Wang (Journal of NeuroVirology, 2021)

Diversity and spatial distribution of endophytic fungi in Cinnamomum longepaniculatum of Yibin, China - Wanhai Zhou; Qin Wei; Ruizhang Feng; Yang Liu; Hanqiao Liang; Jia Li; Kuan Yan (Archives of Microbiology, 2021)

Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons - Xiaolei Song; Haotian Chen; Zicong Shang; Heng Du; Zhenmeiyu Li; Yan Wen; Guoping Liu; Dashi Qi; Yan You; Zhengang Yang; Zhuangzhi Zhang; Zhejun Xu (Neuroscience Bulletin, 2021)
Medium spiny neurons (MSNs) in the striatum, which can be divided into D1 and D2 MSNs, originate from the lateral ganglionic eminence (LGE). Previously, we reported that Six3 is a downstream target of Sp8/Sp9 in the transcriptional regulatory cascade of D2 MSN development and that conditionally knocking out Six3 leads to a severe loss of D2 MSNs. Here, we showed that Six3 mainly functions in D2 MSN precursor cells and gradually loses its function as D2 MSNs mature. Conditional deletion of Six3 had little effect on cell proliferation but blocked the differentiation of D2 MSN precursor cells. In addition, conditional overexpression of Six3 promoted the differentiation of precursor cells in the LGE. We measured an increase of apoptosis in the postnatal striatum of conditional Six3 -knockout mice. This suggests that, in the absence of Six3, abnormally differentiated D2 MSNs are eliminated by programmed cell death. These results further identify Six3 as an important regulatory element during D2 MSN differentiation.

Anti-proliferation and pro-apoptosis effects of miR-582-5p in chronic lymphocytic leukemia via targeting HNRNPA1 and suppression of NF-κB - Zengsheng Wang; Yan Li; Xiaochuan Kuang; Fang Guo; Tao Lang; Min Mao; Xiaoyan Zhang; Haiqing Yang (Molecular & Cellular Toxicology, 2021)

Climate change indirectly enhances sandstorm prevention services by altering ecosystem patterns on the Qinghai-Tibet Plateau - Nan Meng; Yan-zheng Yang; Hua Zheng; Ruo-nan Li (Journal of Mountain Science, 2021)

Complete genome sequence of a novel citrus virus with characteristics of members of the family Tymoviridae - Liu Yang; Song Zhang; Shiqiang Mei; Qiyan Liu; Yan Zhou; Ruhui Li; Mengji Cao (Archives of Virology, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Global patterns and drivers of rainfall partitioning by trees and shrubs - Kai Yue; Pieter De Frenne; Dario A. Fornara; Koenraad Van Meerbeek; Wang Li; Xin Peng; Xiangyin Ni; Yan Peng; Fuzhong Wu; Yusheng Yang; Josep Peñuelas (Global Change Biology, 2021)
Spatiotemporal redistribution of incident rainfall in vegetated ecosystems results from the partitioning by plants into intercepted, stemflow, and throughfall fractions. However, variation in patterns and drivers of rainfall partitioning across global biomes remains poorly understood, which limited the ability of climate models to improve the predictions of biome hydrological cycle under global climate change scenario. Here, we synthesized and analyzed the partitioning of incident rainfall into interception, stemflow, and throughfall by trees and shrubs at the global scale using 2430 observations from 236 independent publications. We found that (1) globally, median levels of relative interception, stemflow, and throughfall accounted for 21.8%, 3.2%, and 73.0% of total incident rainfall, respectively; (2) rainfall partitioning varied among different biomes, due to variation in plant composition, canopy structure, and macroclimate; (3) relative stemflow tended to be driven by plant traits, such as crown height:width ratio, basal area, and height, while relative interception and throughfall tended to be driven by plant traits as well as meteorological variables. Our global assessment of patterns and drivers of rainfall partitioning underpins the role of meteorological factors and plant traits in biome‐specific ecohydrological cycles. We suggest to include these factors in climate models to improve the predictions of local hydrological cycles and associated biodiversity and function responses to changing climate conditions.

Encapsulation and Algicidal Properties of Fermentation Products From Vibrio brasiliensis H115 - Liao Ouyang; Yan Liu; Huirong Chen; Madiha Zaynab; Xuewei Yang; Shilin Wang; Shuangfei Li (Frontiers in Marine Science, 2021)
Algicidal bacteria offer an eco-friendly and promising approach for controlling harmful algae blooms (HABs). In this study, repeated batch fermentation of immobilized algicidal bacterium Vibrio brasiliensis H115 was preformed to enhance the productivity of the algicidal compounds. The highest algicidal efficiency of the fermentation products against Akashiwo sanguinea (100%) was achieved when the fermentation time was decreased from 24 to 14 h. The cell-free fermentation broth was then spray-dried and floating microcapsules were prepared from the dried powder. The optimum preparation conditions for floating microcapsules were: sodium alginate (SA), 3%; CaCO 3 : SA (mass ratio), 3:4; CaCl 2 , 3%; citric acid, 4%; ethylcellulose, 2%; crosslinking time, 30 min. Under the optimal conditions, the floating microcapsules displayed efficient A. sanguinea cell lysis ability and the algicidal efficiency increased from 10.62% (4 h) to 100% (24 h). These results suggest that the floating microcapsules could potentially be practically used for controlling the outbreaks of A. sanguinea .

Research on displacement prediction of step-type landslide under the influence of various environmental factors based on intelligent WCA-ELM in the Three Gorges Reservoir area - Yong-gang Zhang; Xin-quan Chen; Rao-ping Liao; Jun-li Wan; Zheng-ying He; Zi-xin Zhao; Yan Zhang; Zheng-yang Su (Natural Hazards, 2021)

Characteristics of Modern Geostress and Removability of No. 15 Coal Reservoir, Yangquan Mining Area, China - Tengfei Cao; Zhaobiao Yang; Yong Qin; Zhiming Yan; Zhaoying Chen; Chao Li (Natural Resources Research, 2021)

Experimental Research on Adsorption Kinetic Characteristics of CH4, CO2, and N2 in Coal from Junggar Basin, China, at Different Temperatures - Wanjie Sun; Haifei Lin; Shugang Li; Xiangguo Kong; Hang Long; Min Yan; Yang Bai; Jiamin Tian (Natural Resources Research, 2021)

Runx2 deficiency in junctional epithelium of mouse molars decreases the expressions of E-cadherin and junctional adhesion molecule 1 - Yuan Tian; Haiyu Mu; Aiqin Wang; Yan Gao; Zhiheng Dong; Yang Zhao; Cong Li; Li Zhang; Yuguang Gao (Journal of Molecular Histology, 2021)

Luteolin alleviates ulcerative colitis through SHP-1/STAT3 pathway - Bo-Lin Li; Dan-Yang Zhao; Peng-Li Du; Xiao-Tian Wang; Qian Yang; Yan-Ru Cai (Inflammation Research, 2021)

Correction to: Quantifying soil N2O emissions from soil and anaerobically digested swine manure, nitrification and denitrification using 15N isotope labeling method - Qing Yan; Houhua Yang; Lei Yan; Keqiang Zhang; Jiajia Li; Feng Wang (Environmental Science and Pollution Research, 2021)

Quantifying soil N2O emissions from soil and anaerobically digested swine manure, nitrification and denitrification using 15N isotope labeling method - Qing Yan; Houhua Yang; Lei Yan; Keqiang Zhang; Jiajia Li; Feng Wang (Environmental Science and Pollution Research, 2021)

Genesis of the Ordovician Ma55 sub-member dolomites in the Ordos Basin, China - Xiyan Yang; Yawen Li; Yan Zhan; Fei Huo; Xingzhi Wang (Carbonates and Evaporites, 2021)

Generation and identification of endothelial-specific Hrh2 knockout mice - Rui Meng; Wen-Ke Cai; Wen-Mang Xu; Qiang Feng; Ping Wang; Yan-hua Huang; Yu-Xin Fan; Tao Zhou; Qin Yang; Zhi-Ran Li; Gong-Hao He (Transgenic Research, 2021)