Capacity of transportation and spread of COVID-19—an ironical fact for developed countries - Li Ma; Zhuo Yu; Yan Jiao; Lin Lin; Wei Zhong; Sara W. Day; Arnold Postlethwaite; Hong Chen; Qiang Li; Heliang Yin; Gang Wang (Environmental Science and Pollution Research, 2021)

Preferential capture of phosphate by an Enteromorpha prolifera–based biopolymer encapsulating hydrous zirconium oxide nanoparticles - Qian-Qian Zhong; Li Shen; Ya-Qin Zhao; Yu-Cui Hao; Li-Cong Meng; Yan-Juan Liu; Xing Xu; Ya-Nan Shang; Bao-Yu Gao; Qin-Yan Yue (Environmental Science and Pollution Research, 2021)

Mapping fetal brain development based on automated segmentation and 4D brain atlasing - Haotian Li; Guohui Yan; Wanrong Luo; Tingting Liu; Yan Wang; Ruibin Liu; Weihao Zheng; Yi Zhang; Kui Li; Li Zhao; Catherine Limperopoulos; Yu Zou; et al. (Brain Structure and Function, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

Plankton Detection with Adversarial Learning and a Densely Connected Deep Learning Model for Class Imbalanced Distribution - Yan Li; Jiahong Guo; Xiaomin Guo; Zhiqiang Hu; Yu Tian (Journal of Marine Science and Engineering, 2021)
Detecting and classifying the plankton in situ to analyze the population diversity and abundance is fundamental for the understanding of marine planktonic ecosystem. However, the features of plankton are subtle, and the distribution of different plankton taxa is extremely imbalanced in the real marine environment, both of which limit the detection and classification performance of them while implementing the advanced recognition models, especially for the rare taxa. In this paper, a novel plankton detection strategy is proposed combining with a cycle-consistent adversarial network and a densely connected YOLOV3 model, which not only solves the class imbalanced distribution problem of plankton by augmenting data volume for the rare taxa but also reduces the loss of the features in the plankton detection neural network. The mAP of the proposed plankton detection strategy achieved 97.21% and 97.14%, respectively, under two experimental datasets with a difference in the number of rare taxa, which demonstrated the superior performance of plankton detection comparing with other state-of-the-art models. Especially for the rare taxa, the detection accuracy for each rare taxa is improved by about 4.02% on average under the two experimental datasets. Furthermore, the proposed strategy may have the potential to be deployed into an autonomous underwater vehicle for mobile plankton ecosystem observation.

Ziziphus jujuba Mill., a plant used as medicinal food: a review of its phytochemistry, pharmacology, quality control and future research - Shi-Jun Liu; Yan-Ping Lv; Zhi-Shu Tang; Yu Zhang; Hong-Bo Xu; Dong-Bo Zhang; Chun-Li Cui; Hong-Bo Liu; Huan-Huan Sun; Zhong-Xing Song; Si-Min Wei (Phytochemistry Reviews, 2021)

The role of HIF-1α in BCG-stimulated macrophages polarization and their tumoricidal effects in vitro - Pei Zhu; Yuyang Hou; Mengyan Tang; Zheng Jin; Youran Yu; Dong Li; Dongmei Yan; Zehua Dong (Medical Microbiology and Immunology, 2021)

RNA-Seq Transcriptome Analysis of the Liver and Brain of the Black Carp (Mylopharyngodon piceus) During Fasting - Ya-Fan Dai; Yu-bang Shen; Shen-Tong Wang; Jia-Hua Zhang; Yu-Hong Su; Sheng-Chen Bao; Xiao-Yan Xu; Jia-Le Li (Marine Biotechnology, 2021)

Regional consumption, material flows, and their driving forces: A case study of China's Beijing–Tianjin–Hebei (Jing–Jin–Ji) urban agglomeration - Yanxian Li; Jiawen Wang; Dan Xian; Yan Zhang; Xiangyi Yu (Journal of Industrial Ecology, 2021)
Continuous urbanization and a coordinated regional development strategy have gradually shaped urban agglomerations as new and massive centers of resource consumption in China. Therefore, understanding the material consumption status and the underlying mechanisms for typical Chinese urban agglomerations will support efforts to promote regional resource‐utilization sustainability. In this study, we analyzed material consumption and its structure in the Beijing–Tianjin–Hebei (Jing–Jin–Ji) urban agglomeration from 2000 to 2015 and traced the sources of material consumption and underlying processes from a metabolic perspective. We also identified the main contributors and key drivers behind the changes of consumption during this period. The urban agglomeration's total consumption increased 2.2 times compared to the 2,000 level during the study period, with metallic minerals accounting for the largest proportion. Highly developed cities, including Beijing, Tianjin, Shijiazhuang, Tangshan, and Handan, consumed the largest amounts of materials and generated the most wastes. These cities also relied heavily on both internal and external resources and exchanged materials frequently among their metabolic compartments. Economic activity was the strongest contributor to the increased material consumption, followed by the population increase, whereas decreasing material‐consumption intensity (increased efficiency) restrained the growth of material consumption somewhat. Our application of the material‐flow accounting framework at the scale of an urban agglomeration provides support for future research on material consumption in other typical urban agglomerations, where it can provide support for policy development to alleviate regional resource shortages.

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

Generation and identification of endothelial-specific Hrh2 knockout mice - Rui Meng; Wen-Ke Cai; Wen-Mang Xu; Qiang Feng; Ping Wang; Yan-hua Huang; Yu-Xin Fan; Tao Zhou; Qin Yang; Zhi-Ran Li; Gong-Hao He (Transgenic Research, 2021)

Paeoniflorin reduces the inflammatory response of THP-1 cells by up‐regulating microRNA-124 - Danyun Huang; Zhijun Li; Yue Chen; Yan Fan; Tao Yu (Genes & Genomics, 2021)
Background The activation of macrophages and the release of inflammatory cytokines are the main reasons for the progress of systemic lupus erythematosus (SLE). MicroRNA (miRNA)-124 is involved in the regulation of macrophages and is a key regulator of inflammation and immunity. Objective To explore whether paeoniflorin (PF) regulates the biological functions of macrophages depends on miR-124. Methods RT-PCR, WB, ELISA, CCK-8 and flow cytometry were used to evaluate that PF regulated the biological functions of THP-1 cells through miR-124. Results PF significantly inhibited the proliferation while promotes the apoptosis of THP-1 cells, and inhibited the release of IL-6, TNF-α and IL-1βin THP-1 cells. RT-PCR results shown that PF up-regulated the expression of miR-124 in THP-1 cells. Functional recovery experiments showed that compared with the LPS + mimic-NC group, LPS + miR-124 mimic significantly inhibited the proliferation and the release of IL-6, TNF-α and IL-1β, but promoted the apoptosis of THP-1 cells. In addition, compared with the LPS + PF + inhibitor-NC group, LPS + PF + miR-124 inhibitor significantly promoted the proliferation and the release of IL-6, TNF-α and IL-1β, but inhibited the apoptosis of THP-1 cells. Conclusions By down-regulating miR-124, PF inhibits the proliferation and inflammation of THP-1 cells, and promotes the apoptosis of THP-1 cells.

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Tracking historical chlorophyll- a change in the guanting reservoir, Northern China, based on landsat series inter-sensor normalization - Fangfang Zhang; Junsheng Li; Bokun Yan; Junchuan Yu; Chao Wang; Shenglei Wang; Qian Shen; Yanhong Wu; Bing Zhang (International Journal of Remote Sensing, 2021)

Design of supercontinuum laser hyperspectral light detection and ranging (LiDAR) (SCLaHS LiDAR) - Guoqing Zhou; Xiang Zhou; Youjian Song; Donghui Xie; Long Wang; Guangjian Yan; Minglie Hu; Bowen Liu; Weidong Shang; Chenghu Gong; Cheng Wang; Huaguo Huang; et al. (International Journal of Remote Sensing, 2021)

A cloud classification method based on random forest for FY-4A - Zhuofu Yu; Shuo Ma; Ding Han; Guanlin Li; Ding Gao; Wei Yan (International Journal of Remote Sensing, 2021)

Apatinib regulates the growth of gastric cancer cells by modulating apoptosis and autophagy - Xu Liu; Qiaoyu Zheng; Qiongfang Yu; Yan Hu; Yanmin Cheng; Zhaozhao Shao; Li Chen; Wenjie Ding; Dian Gao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Prediction model based on the Laplacian eigenmap method combined with a random forest algorithm for rainstorm satellite images during the first annual rainy season in South China - Xiao-yan Huang; Li He; Hua-sheng Zhao; Ying Huang; Yu-shuang Wu (Natural Hazards, 2021)

Antifungal Effect of Long Noncoding RNA 9708-1 in the Vulvovaginal Candidiasis Murine Model - Ying Wu; Lisha Jiang; Lingling Zhang; Xia Liu; Lina Yan; Ting Luan; Can Rui; Zhiyuan Mao; Chong Fan; Yu Liu; Ping Li; Xin Zeng (Mycopathologia, 2021)
Vulvovaginal candidiasis (VVC) caused by Candida spp. affects 70–75% of women at least once during their lives. We aim to elucidate the potential mechanism of VVC and investigate the therapeutic effects of long noncoding RNA 9708-1. Female BALB/c mice were randomized to four treatment groups, including the blank control group, VVC control group, vehicle control group and lncRNA 9708-1-overexpressed group. Mice were euthanized on Day 4, Day 7 and Day 14 after treatment. Colony-forming unit (CFU) was measured, and the inflammation was detected by hematoxylin and eosin (H&E). Gene and protein expression levels of lncRNA 9708-1 and FAK were determined by real-time PCR, Western blot and immunohistochemistry. The overexpression of lncRNA 9708-1 significantly decreased the fungal load from Day 4 to 7. H&E staining indicated that the impaired histological profiles were improved in lncRNA 9708-1-overexpressed group. LncRNA 9708-1 led to a significant increase in FAK level of vagina tissue which is expressed mainly in epithelial basal layer. This study suggests that lncRNA 9708-1 played a protective role on murine experimental VVC by upregulating the expression levels of FAK.

Guangdong’s embodied carbon emission in China’s inter-provincial trade based on MRIO model - Chen Yu; Takeshi Mizunoya; Jingjing Yan; Li Li (Environmental Science and Pollution Research, 2021)

Spatiotemporal variation of nitrogen and phosphorus and its main influencing factors in Huangshui River basin - Biqiong Dong; Tianling Qin; Yu Wang; Yan Zhao; Shanshan Liu; Jianming Feng; Chenhao Li; Xin Zhang (Environmental Monitoring and Assessment, 2021)
The foundation of managing excess nutrients in river is the identification of key physical processes and the control of decisive influencing factors. The existing studies seldom consider the influence of rainfall-runoff relationship and only focus on a few anthropogenic activities and natural attributes factors. To address this issue, a comprehensive set of influencing factors including rainfall-runoff relationship (represented by runoff coefficient), basic physical and chemical parameters of water quality, land use types, landscape patterns, topography, and socioeconomic development was constructed in this study. M–K test and cluster analysis were conducted to identify the temporal mutation and spatial clustering characteristics of NH 3 -N and TP in Huangshui River basin, respectively. Partial least squares regression was used to elucidate the linkages between water contaminants and the factors. As shown in the results, the temporal mutations of NH 3 -N and TP were obvious in the middle reaches, with 4 out of 7 catchments in the middle reaches have a larger number of mutations of NH 3 -N than other catchments. The cluster analysis results of NH 3 -N and TP among catchments were similar. This study also indicated that although the Huangshui River basin was located in the upper reaches of the Yellow River, the influences of rainfall-runoff relationship on spatiotemporal changes of NH 3 -N and TP in its sub-basins were limited. Only the temporal change of NH 3 -N in Jintan catchment in the upstream area was significantly affected by runoff coefficient. The indexes of proportion of water area (PWA), proportion of impervious area (PIA), and proportion of primary industry (PPI) were the top three influencing factors of temporal variation of NH 3 -N and TP for most catchments in the middle reaches. The temporal change of NH 3 -N in Jintan catchment in the upstream area was obviously affected by runoff coefficient. The spatial variation of NH 3 -N and TP were all affected by PWA and proportion of secondary industry significantly. The results of this study can provide theoretical basis and technical support for the control and management of nitrogen and phosphorus pollution in upper reaches of rivers.

Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling - Size Li; Yiqun Yu; Xiaolan Bian; Li Yao; Min Li; Yan-Ru Lou; Jing Yuan; Hai-shu Lin; Lucy Liu; Bing Han; Xiaoqiang Xiang (Archives of Toxicology, 2021)

Study on characteristics of waterflooding in fractured reservoirs based on discrete fracture model - Fanle Meng; Junjian Li; Hanqiao Jiang; Lin Zhao; Linkai Li; Yan Qiao; Yu Zhou; Fei Xu (Arabian Journal of Geosciences, 2021)

Rapid Modeling of the Sound Speed Field in the South China Sea Based on a Comprehensive Optimal LM-BP Artificial Neural Network - Jin Huang; Yu Luo; Jian Shi; Xin Ma; Qian-Qian Li; Yan-Yi Li (Journal of Marine Science and Engineering, 2021)
Ocean sound speed is an essential foundation for marine scientific research and marine engineering applications. In this article, a model based on a comprehensive optimal back propagation artificial neural network model is developed. The Levenberg–Marquardt algorithm is used to optimize the model, and the momentum term, normalization, and early termination method were used to predict the high precision marine sound speed profile. The sound speed profile was described by five indicators: date, time, latitude, longitude, and depth. The model used data from the CTD observation dataset of scientific investigation over the South China Sea (2009–2012) (108°–120° E, 6°–8° N), which includes comprehensive scientific investigation data from four voyages. The feasibility of modeling the sound speed field in the South China Sea is investigated. The proposed model uses the momentum term, normalization, and early termination in a traditional BP artificial neural network structure and mitigates issues with overtraining and difficulty when determining the BP neural network parameters. With the LM algorithm, a fast-modeling method for the sound field effectively achieves the precision requirement for sound speed prediction. Through the prediction and verification of the data from 2009 to 2012, the newly proposed optimized BP network model is shown to dramatically reduce the training time and improve precision compared to the traditional network model. Results showed that the root mean squared error decreased from 1.7903 m/s to 0.95732 m/s, and the training time decreased from 612.43 s to 4.231 s. Finally, the sound ray tracing simulations confirm that the model meets the accuracy requirements of acoustic sounding and verify the model’s feasibility for the real-time prediction of the vertical sound speed in saltwater bodies.

Termite mounds reduce soil microbial diversity by filtering rare microbial taxa - Qing‐Lin Chen; Hang‐Wei Hu; Zhen‐Zhen Yan; Chao‐Yu Li; Bao‐Anh Thi Nguyen; Yong Zheng; Yong‐Guan Zhu; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Termites are ubiquitous insects in tropical and subtropical habitats, and some of them construct massive nests (‘mounds’), which substantially promote substrate heterogeneity by altering soil properties. Yet, the role of termite nesting process in regulating the distribution and diversity of soil microbial communities remains poorly understood, which introduces uncertainty in predictions of ecosystem functions of termite mounds in a changing environment. Here, by using amplicon sequencing, we conducted a survey of 134 termite mounds across >1500 km in northern Australia and found that termite mounds significantly differed from bulk soils in the microbial diversity and community compositions. Compared with bulk soils, termite nesting process decreased the microbial diversity and the relative abundance of rare taxa. Rare taxa had a narrower habitat niche breadth than dominant taxa and might be easier to be filtered by the potential intensive microbial competition during the nesting processes. We further demonstrated that the shift in pH induced by termite nesting process was a major driver shaping the microbial community profiles in termite mounds. Together, our work provides novel evidence that termite nesting is an important process in regulating soil microbial diversity, which advances our understanding of the functioning of termite mounds.

Human β-Defensin 118 Attenuates Escherichia coli K88–Induced Inflammation and Intestinal Injury in Mice - Qian Lin; Qingqing Fu; Xiang Li; Yuheng Luo; Junqiu Luo; Daiwen Chen; Xiangbing Mao; Bing Yu; Ping Zheng; Zhiqing Huang; Jie Yu; Hui Yan; et al. (Probiotics and Antimicrobial Proteins, 2021)

A Photopolymerized Semi-Interpenetrating Polymer Networks-Based Hydrogel Incorporated with Nanoparticle for Local Chemotherapy of Tumors - Yeying Wang; Qilong Li; Jing-e Zhou; Jingwen Tan; Minghao Li; Nan Xu; Feng Qu; Jian Chen; Ji Li; Jing Wang; Zhiqiang Liang; Lei Yu; et al. (Pharmaceutical Research, 2021)

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

The Roles of Epinephelus coioides miR-122 in SGIV Infection and Replication - Hong-Yan Sun; Yu-Ling Su; Pin-Hong Li; Jia-Yang He; He-Jia Chen; Gang Wang; Shao-Wen Wang; Xiao-Hong Huang; You-Hua Huang; Qi-Wei Qin (Marine Biotechnology, 2021)
In mammals, mature miR-122 is 22 nucleotides long and can be involved in regulating a variety of physiological and biological pathways. In this study, the expression profile and effects of grouper Epinephelus coioides miR-122 response to Singapore grouper iridovirus (SGIV) infection were investigated. The sequences of mature microRNAs (miRNAs) from different organisms are highly conserved, and miR-122 from E. coioides exhibits high similarity to that from mammals and other fish. The expression of miR-122 was up-regulated during SGIV infection. Up-regulation of miR-122 could significantly enhance the cytopathic effects (CPE) induced by SGIV, the transcription levels of viral genes (MCP, VP19, LITAF and ICP18), and viral replication; reduce the expression of inflammatory factors (TNF-a, IL-6, and IL-8), and the activity of AP-1 and NF-κB, and miR-122 can bind the target gene p38α MAPK to regulate the SGIV-induced cell apoptosis and the protease activity of caspase-3. The results indicated that SGIV infection can up-regulate the expression of E. coioides miR-122, and up-regulation of miR-122 can affect the activation of inflammatory factors, the activity of AP-1 and NF-κB, and cell apoptosis to regulate viral replication and proliferation.

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Nitrogen Enrichment Reduces Nitrogen and Phosphorus Resorption Through Changes to Species Resorption and Plant Community Composition - Xiao-Tao Lü; Shuang-Li Hou; Sasha Reed; Jiang-Xia Yin; Yan-Yu Hu; Hai-Wei Wei; Zhi-Wei Zhang; Guo-Jiao Yang; Zhuo-Yi Liu; Xing-Guo Han (Ecosystems, 2021)

Chelativorans alearense sp. nov., A Novel Bacterial Species Isolated From Soil in Alear, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Current Microbiology, 2021)

Correction to: Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Bai; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Ba; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

Nesterenkonia haasae sp. nov., an alkaliphilic actinobacterium isolated from a degraded pasture in Songnen Plain - Shuang Wang; Lei Sun; Dan Wei; Nimaichand Salam; Bao-Zhu Fang; Zhou-Yan Dong; Xiao-Yu Hao; Mingyi Zhang; Zhe Zhang; Wen-Jun Li (Archives of Microbiology, 2021)

The effects of land use changes on climate warming by source-sink theory - Shuang-shuang Hou; Li-fei Yu; Wei Yan; Shu-hong Gu; Xiao-ping Gu (Arabian Journal of Geosciences, 2021)

Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation - Xiaoli Liu; Yan Gu; Yaoyao Bian; Danhong Cai; Yu Li; Ye Zhao; Zhaofeng Zhang; Mei Xue; Liang Zhang (Apoptosis, 2021)
Acute promyelocytic leukemia (APL) is a blood system disease caused by the accumulation of a large number of immature blood cells in bone marrow. Although the introduction of all- trans retinoic acid (ATRA) and arsenic has reached a high level of complete remission rate and 5-year disease-free survival rate, the occurrence of various adverse reactions still severely affects the quality of life of patients. As a natural product, honokiol (HNK) has the advantages of low toxicity and high efficiency, and it is a potential drug for the treatment of cancer. Since cancer cells can escape apoptotic cell death through multiple adaptive mechanisms, HNK, a drug that induces cancer cell death in a nonapoptotic way, has attracted much interest. We found that HNK reduced the viability of human APL cell line (NB4 cells) by inducing paraptosis-like cell death. The process was accompanied by excessive reactive oxygen species (ROS), mitochondrial damage, endoplasmic reticulum stress, and increased microtubule-associated protein 1 light chain 3 (LC3) processing. The inactivation of proteasome activity was the main cause of misfolded and unfolded protein accumulation in endoplasmic reticulum, such as LC3II/I and p62. This phenomenon could be alleviated by adding cycloheximide (CHX), a protein synthesis inhibitor. We found that mTOR signaling pathway participated in paraptosis-like cell death induced by HNK in an autophagy-independent process. Moreover, the mitogen-activated protein kinase (MAPK) signaling pathway induced paraptosis of NB4 cells by promoting endoplasmic reticulum stress. In summary, these findings indicate that paraptosis may be a new way to treat APL, and provide novel insights into the potential mechanism of paraptosis-like cell death.

Global patterns in leaf stoichiometry across coastal wetlands - Yu‐Kun Hu; Xu‐Yan Liu; Nian‐Peng He; Xu Pan; Song‐Yuan Long; Wei Li; Man‐Yin Zhang; Li‐Juan Cui (Global Ecology and Biogeography, 2021)
Aim Coastal wetlands provide crucial ecosystem functions and services, such as coastal protection, nutrient retention and C sequestration. Despite the important roles in global C, N and P cycling, the global variation in leaf stoichiometry across coastal wetlands remains unclear. Location Global. Time period 1980–2018. Major taxa studied Vascular plants. Methods By compiling a global dataset of 698 data records in 205 sites, we carried out systematic analyses of the world‐wide trends and their determinants of leaf element contents and ratios of plants across coastal wetlands. Results Leaf N and P contents increased significantly, but C:N, C:P and N:P ratios decreased with increasing latitude in coastal wetlands. The mean annual temperature was the predominant driver of leaf N, P and C:N, whereas soil N:P was a good predictor of leaf C:P and N:P ratios. Furthermore, N increased faster with P in plant leaves of coastal wetlands compared with terrestrial ecosystems. Within coastal wetlands, herb‐dominated salt marshes had a significantly higher leaf P content, lower leaf N:P ratio and lower scaling exponent of leaf N to P than tree‐dominated mangroves. Main conclusions The similar latitudinal patterns of leaf stoichiometry in coastal wetlands compared with terrestrial ecosystems reflected the similar influences of temperature. However, different slopes of leaf P and N:P ratios and N and P scaling relationships between these two ecosystems suggested that different salinity and tidal inundation levels result in different strategies of N and P use in coastal wetland plants. These differences in leaf stoichiometry between ecosystems and between different types of coastal wetlands might need to be emphasized in future biogeochemical modelling owing to their different roles in global nutrient and carbon cycling.

EmhR is an indole‐sensing transcriptional regulator responsible for the indole‐induced antibiotic tolerance in Pseudomonas fluorescens - Jian‐Ting Han; Di‐Yin Li; Meng‐Yuan Zhang; Xiao‐Quan Yu; Xiang‐Xue Jia; Hang Xu; Xu Yan; Wen‐Juan Jia; Shaomin Niu; Megan L. Kempher; Xuanyu Tao; Yong‐Xing He (Environmental Microbiology, 2021)
Summary Indole is well known as an interspecies signalling molecule to modulate bacterial physiology; however, it is not clear how the indole signal is perceived and responded to by plant growth promoting rhizobacteria (PGPR) in the rhizosphere. Here, we demonstrated that indole enhanced the antibiotic tolerance of Pseudomonas fluorescens 2P24, a PGPR well known for its biocontrol capacity. Proteomic analysis revealed that indole influenced the expression of multiple genes including the emhABC operon encoding a major multidrug efflux pump. The expression of emhABC was regulated by a TetR‐family transcription factor EmhR, which was demonstrated to be an indole‐responsive regulator. Molecular dynamics simulation showed that indole allosterically affected the distance between the two DNA‐recognizing helices within the EmhR dimer, leading to diminished EmhR–DNA interaction. It was further revealed the EmhR ortholog in Pseudomonas syringae was also responsible for indole‐induced antibiotic tolerance, suggesting this EmhR‐dependent, indole‐induced antibiotic tolerance is likely to be conserved among Pseudomonas species. Taken together, our results elucidated the molecular mechanism of indole‐induced antibiotic tolerance in Pseudomonas species and had important implications on how rhizobacteria sense and respond to indole in the rhizosphere.

Transcriptome sequencing and analysis for the pigmentation of scale and skin in common carp (Cyprinus carpio) - Yu-Jie Zhao; Jun Xiao; Mei-Di Huangyang; Ran Zhao; Qi Wang; Yan Zhang; Jiong-Tang Li (Molecular Biology Reports, 2021)

Laboratory simulation of dissolved oxygen reduction and ammonia nitrogen generation in the decay stage of harmful algae bloom - Qiaoning Wang; Xiaodong Li; Tian Yan; Jingjing Song; Rencheng Yu; Mingjiang Zhou (Journal of Oceanology and Limnology, 2021)

High-Level Expression and Purification of Melittin in Escherichia coli Using SUMO Fusion Partner - Qiu-chi Chen; Lei Liu; Tian-Yi Yu; Lu Tang; Mo-li Yin; Wen-he Zhu; Xiu-yun Jiang; Hui-yan Wang (International Journal of Peptide Research and Therapeutics, 2021)

Maternal exposure to ambient SO2 and risk of polydactyly and syndactyly: a population-based case-control study in Liaoning Province, China - Yu-Ting Jiang; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; Qi-Jun Wu (Environmental Science and Pollution Research, 2021)

Sporothrix globosa melanin inhibits antigenpresentation by macrophages and enhances deep organ dissemination - Yang Song; Lei Yao; Yu Zhen; Yan Cui; Shuxia Zhong; Yuanyuan Liu; Shanshan Li (Brazilian Journal of Microbiology, 2021)

In vitro antifungal susceptibility of Sporothrix globosa isolates from Jilin Province, northeastern China: comparison of yeast and mycelial phases - Yang Song; Shanshan Li; Ying Shi; Lipei Zhao; Yu Cui; Lei Yao; Yu Zhen; Ruili Chen; Yan Cui (Brazilian Journal of Microbiology, 2021)

Freeze-thaw resistance of eco-material stabilized loess - Guo-yu Li; Xin Hou; Yu Zhou; Wei Ma; Yan-hu Mu; Dun Chen; Li-yun Tang (Journal of Mountain Science, 2021)

Chelativorans xinjiangense sp. nov., a novel bacterial species isolated from soil in Xinjiang, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Archives of Microbiology, 2021)

Mechanisms of niche‐neutrality balancing can drive the assembling of microbial community - Lixiao Wang; Maozhen Han; Xi Li; Bingbing Yu; Huading Wang; Amjed Ginawi; Kang Ning; Yunjun Yan (Molecular Ecology, 2021)
One hotspot of present community ecology is to uncover the mechanisms of community succession. In this study, two popular concepts, niche‐neutrality dynamic balancing and co‐occurrence network analysis, were integrated to investigate the dispersal dynamics of microbial communities in a freshwater river continuum in subtropical China. Results showed that when habitat conditions were mild and appropriate, such as in the clean upstream river, free of heavy pollution or long‐lasting extreme disturbances, stochastic processes could increase species diversities, and organize communities into relatively loosely linked and stable networks with higher modularity and more modules. However, when conditions became degraded under heavy pollution, the influence of neutrality diminished, and niche‐based selection imposed more constraints on communities and guided the assembling processes in certain directions: depleting species richness, strengthening interspecies connections and breaking boundaries of modules. Consequently, communities became more sensitive to fluctuations so as to deal with the harsh conditions efficiently. Another interesting finding was that, both as keystone taxa of communities, module hubs were mostly neutrally distributed generalists with high abundances, and were beneficial to many related operational taxonomic units. In contrast, connectors were less abundant and their distributions were more subjected to the environments. Therefore, connectors were probably responsible for the information transmission between microbial communities and environments, as well as between different modules, and thus could restrict the dispersal of microbes and guide the direction of community assembly.

Estimation of rice plant potassium accumulation based on non-negative matrix factorization using hyperspectral reflectance - Jingshan Lu; Wanyu Li; Minglei Yu; Xiangbin Zhang; Yong Ma; Xi Su; Xia Yao; Tao Cheng; Yan Zhu; Weixing Cao; Yongchao Tian (Precision Agriculture, 2021)

Down-regulation of MANNANASE7 gene in Brassica napus L. enhances silique dehiscence-resistance - Yu-Long Li; Yan-Kun Yu; Ke-Ming Zhu; Li-Na Ding; Zheng Wang; Yan-Hua Yang; Jun Cao; Li-Zhang Xu; Yao-Ming Li; Xiao-Li Tan (Plant Cell Reports, 2021)

The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish - Si-Lan Han; Yan Liu; Samwel M. Limbu; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2021)

Association between selected urinary heavy metals and asthma in adults: a retrospective cross-sectional study of the US National Health and Nutrition Examination Survey - Xiuzhu Li; Yun Fan; Yan Zhang; Xiaomin Huang; Zhenyao Huang; Mingming Yu; Qiaoqiao Xu; Xiumei Han; Chuncheng Lu; Xinru Wang (Environmental Science and Pollution Research, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

Nodule Rich Protein 2 modulates nodule number in Medicago truncatula - Junhui Yan; Xinwei Yang; Yawen Wang; Liangliang Yu; Li Luo (Plant Biotechnology Reports, 2021)

Effect of soil moisture on pupation behavior and inhabitation of Spodoptera frugiperda (Lepidoptera: Noctuidae) - Yan Shi; Lin-Yu Li; Sohaib Shahid; Guy Smagghe; Tong-Xian Liu (Applied Entomology and Zoology, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Transient Responses Evaluation of FPSO with Different Failure Scenarios of Mooring Lines - Dongsheng Qiao; Binbin Li; Jun Yan; Yu Qin; Haizhi Liang; Dezhi Ning (Journal of Marine Science and Engineering, 2021)
During the long-term service condition, the mooring line of the deep-water floating platform may fail due to various reasons, such as overloading caused by an accidental condition or performance deterioration. Therefore, the safety performance under the transient responses process should be evaluated in advance, during the design phase. A series of time-domain numerical simulations for evaluating the performance changes of a Floating Production Storage and Offloading (FPSO) with different broken modes of mooring lines was carried out. The broken conditions include the single mooring line or two mooring lines failure under ipsilateral, opposite, and adjacent sides. The resulting transient and following steady-state responses of the vessel and the mooring line tensions were analyzed, and the corresponding influence mechanism was investigated. The accidental failure of a single or two mooring lines changes the watch circle of the vessel and the tension redistribution of the remaining mooring lines. The results indicated that the failure of mooring lines mainly influences the responses of sway, surge, and yaw, and the change rule is closely related to the stiffness and symmetry of the mooring system. The simulation results could give a profound understanding of the transient-effects influence process of mooring line failure, and the suggestions are given to account for the transient effects in the design of the mooring system.

Preparation, Characterization, and In Vitro Pharmacodynamics and Pharmacokinetics Evaluation of PEGylated Urolithin A Liposomes - Shengfu Yi; Cong Zhang; Junjie Hu; Yan Meng; Liang Chen; Huifan Yu; Shan Li; Guihong Wang; Guohua Zheng; Zhenpeng Qiu (AAPS PharmSciTech, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Physical mapping of chromosome 7J and a purple coleoptile gene from Thinopyrum intermedium in the common wheat background - Jianbo Li; Zhihui Yu; Ahui Zhang; Yan Yin; Lingrong Tang; Guangrong Li; Peng Zhang; Imtiaz Ahmed Khan; Ian Dundas; Zujun Yang (Planta, 2021)

Advances in intervention methods and brain protection mechanisms of in situ and remote ischemic postconditioning - Chun-Yan Li; Wei Ma; Kuang-Pin Liu; Jin-Wei Yang; Xian-Bin Wang; Zhen Wu; Tong Zhang; Jia-Wei Wang; Wei Liu; Jie Liu; Yu Liang; Xing-Kui Zhang; et al. (Metabolic Brain Disease, 2021)

Improved control of Frankliniella occidentalis on greenhouse pepper through the integration of Orius sauteri and neonicotinoid insecticides - Qing-cai Lin; Hao Chen; Dirk Babendreier; Jin-ping Zhang; Feng Zhang; Xiao-yan Dai; Zuo-wen Sun; Zhao-peng Shi; Xiao-lin Dong; Guang-an Wu; Yi Yu; Li Zheng; et al. (Journal of Pest Science, 2021)

Distance decay of place attachment and perceived authenticity of mountain tourism destinations in China - Xiao Xiao; Jie Zhang; Jun-yu Lu; Li Li; Yan-qing Xu; Hong-lei Zhang; Geoffrey K. Riungu (Journal of Mountain Science, 2021)

Correction to: Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Chang-Qi Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Connexin 36 Mediates Orofacial Pain Hypersensitivity Through GluK2 and TRPA1 - Qian Li; Tian-Le Ma; You-Qi Qiu; Wen-Qiang Cui; Teng Chen; Wen-Wen Zhang; Jing Wang; Qi-Liang Mao-Ying; Wen-Li Mi; Yan-Qing Wang; Yu-Xia Chu (Neuroscience Bulletin, 2020)

Image-Forming Visual Basis of Empathy for Pain in Mice - Kai-Wen Geng; Rui Du; Na Wei; Chun-Li Li; Yan Wang; Wei Sun; Tao Chen; Dong-Yu Wei; Yang Yu; Ting He; Wen-Jun Luo; Rui-Rui Wang; et al. (Neuroscience Bulletin, 2020)

Factors associated with a SARS-CoV-2 recurrence after hospital discharge among patients with COVID-19: systematic review and meta-analysis - Meng-qi Yao; Qiu-xian Zheng; Jia Xu; Jing-wen Deng; Tian-tian Ge; Hai-bo Zhou; Feng-tian Wu; Xin-yu Gu; Qin Yang; Yan-li Ren; Gang Wang; Zhi Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Enrichment of cadmium in rice (Oryza sativa L.) grown under different exogenous pollution sources - Yi-Min Zhou; Si-Si Long; Bing-Yu Li; Ya-Yuan Huang; Yong-Jie Li; Jia-Yan Yu; Hui-Hui Du; Sardar Khan; Ming Lei (Environmental Science and Pollution Research, 2020)

Psychological symptoms in Chinese nurses may be associated with predisposition to chronic disease: a cross-sectional study of suboptimal health status - Jinxiu Zhu; Wenjuan Ying; Li Zhang; Gangyi Peng; Weiju Chen; Enoch Odame Anto; Xueqing Wang; Nan Lu; Shanshan Gao; Guihai Wu; Jingyi Yan; Jianfeng Ye; et al. (EPMA Journal, 2020)
Background Suboptimal health status (SHS) is a reversible state between ideal health and illness and it can be effectively reversed by risk prediction, disease prevention, and personalized medicine under the global background of predictive, preventive, and personalized medicine (PPPM) concepts. More and more Chinese nurses have been troubled by psychological symptoms (PS). The correlation between PS and SHS is unclear in nurses. The purpose of current study is to investigate the prevalence of SHS and PS in Chinese nurses and the relationship between SHS and PS along with predisposing factors as well as to discuss the feasibility of improving health status and preventing diseases according to PPPM concepts in Chinese nurses. Methods A cross-sectional study was conducted with the cluster sampling method among 9793 registered nurses in Foshan city, China. SHS was evaluated with the Suboptimal Health Status Questionnaire-25 (SHSQ-25). Meanwhile, the PS of depression and anxiety were evaluated with Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) self-assessment questionnaires. The relationship between PS and SHS in Chinese nurses was subsequently analyzed. Results Among the 9793 participants, 6107 nurses were included in the final analysis. The prevalence of SHS in the participants was 74.21% (4532/6107) while the symptoms of depression and anxiety were 47.62% (2908/6107) and 24.59% (1502/6107) respectively. The prevalence of SHS in the participants with depression and anxiety was significantly higher than those without the symptoms of depression (83.3% vs 16.7%, P < 0.001) and anxiety (94.2% vs 5.8%, P < 0.0001). The ratio of exercise habit was significantly lower than that of non-exercise habit (68.8% vs 78.4%, P < 0.001) in SHS group. Conclusions There is a high prevalence of SHS and PS in Chinese nurses. PS in Chinese nurses are associated with SHS. Physical exercise is a protective factor for SHS and PS so that the exercise should be strongly recommended as a valuable preventive measure well in the agreement with PPPM philosophy. Along with SDS and SAS, SHSQ-25 should also be highly recommended and applied as a novel predictive/preventive tool for the health measures from the perspectives of PPPM in view of susceptible population and individual screening, the predisposition to chronic disease preventing, personalization of intervention, and the ideal health state restoring.

Assessment of Heavy Metal Pollution in Soil and Classification of Pollution Risk Management and Control Zones in the Industrial Developed City - Mingtao Xiang; Yan Li; Jiayu Yang; Yi Li; Feng Li; Bifeng Hu; Yu Cao (Environmental Management, 2020)

Rapid identification of landslide, collapse and crack based on low-altitude remote sensing image of UAV - Xu-gang Lian; Zou-jun Li; Hong-yan Yuan; Ji-bo Liu; Yan-jun Zhang; Xiao-yu Liu; Yan-ru Wu (Journal of Mountain Science, 2020)

Deformation and failure of a high-steep slope induced by multi-layer coal mining - Jian-le Yu; Jian-jun Zhao; Hao-yuan Yan; Qi-yi Lai; Run-qiu Huang; Xiu-wei Liu; Yang-chnn Li (Journal of Mountain Science, 2020)

Correlation between DNA methylation and Thymic Stromal Lymphopoietin expression in asthmatic airway epithelial cells - Yan-Li Li; Xi-Qian Xing; Yi Xiao; Yan-Hong Liu; Yu-Shan Zhou; Min Zhuang; Chao-Qian Li (Genes & Genomics, 2020)

Identification of hybrid green peafowl using mitochondrial and nuclear markers - Han Yu Du; Xin Yuan Zhang; Thi Dao Dinh; Yue Ma; Cheng Zong; Guang Long Li; Thomas D. Dahmer; Yan Chun Xu (Conservation Genetics Resources, 2020)

Modeling of CHAMP satellite data according to the 3D surface spline model of geomagnetic fields - Yan Feng; Huang Ya; Liu Shuang; Li Yu-jun; Jiang Yi (Applied Geophysics, 2020)

Experiments on excitation and data processing of low-frequency vibroseis in permafrost area of the tibetan plateau - Yu-Kun Tian; Hai-xia Kang; Jie Cao; Juan Li; Hui Zhou; Yan-Yan Ma (Applied Geophysics, 2020)

Prediction study of hydrocarbon reservoir based on time–frequency domain electromagnetic technique taking Ili Basin as an example - Yu-Kun Tian; Hui Zhou; Yan-Yan Ma; Juan Li (Applied Geophysics, 2020)

Flavonoids repress the production of antifungal 2, 4‐DAPG but potentially facilitate root colonization of the rhizobacterium Pseudomonas fluorescens - Xiao‐Quan Yu; Xu Yan; Meng‐Yuan Zhang; Li‐Qun Zhang; Yong‐Xing He (Environmental Microbiology, 2020)
Summary In the well‐known legume–rhizobia symbiosis, flavonoids released by legume roots induce expression of the Nod factors and trigger early plant responses involved in root nodulation. However, it remains largely unknown how the plant‐derived flavonoids influence the physiology of non‐symbiotic beneficial rhizobacteria. In this work, we demonstrated that the flavonoids apigenin and/or phloretin enhanced the swarming motility and production of cellulose and curli in Pseudomonas fluorescens 2P24, both traits of which are essential for root colonization. Using a label‐free quantitative proteomics approach, we showed that apigenin and phloretin significantly reduced the biosynthesis of the antifungal metabolite 2,4‐DAPG and further identified a novel flavonoid‐sensing TetR regulator PhlH, which was shown to modulate 2,4‐DAPG production by regulating the expression of 2,4‐DAPG hydrolase PhlG. Although having similar structures, apigenin and phloretin could also influence different physiological characteristics of P . fluorescens 2P24, with apigenin decreasing the biofilm formation and phloretin inducing expression of proteins involved in the denitrification and arginine fermentation processes. Taken together, our results suggest that plant‐derived flavonoids could be sensed by the TetR regulator PhlH in P . fluorescens 2P24 and acts as important signalling molecules that strengthen mutually beneficial interactions between plants and non‐symbiotic beneficial rhizobacteria.

Solanrubiellin A, a hydroanthraquinone dimer with antibacterial and cytotoxic activity from Solanum lyratum - Hui Chen; Kun Du; Yan-Jun Sun; Zhi-You Hao; Yan-Li Zhang; Jiang Bai; Qing-Hua Wang; Hai-Yu Hu; Wei-Sheng Feng (Natural Product Research, 2020)

Identification of AP2/ERF genes in apple (Malus × domestica) and demonstration that MdERF017 enhances iron deficiency tolerance - Li Cheng; Tong Zhao; Yu-Xia Wu; Hai Wang; Zhong-Xing Zhang; De Zhang; Shuang-Cheng Wang; Yan-Xiu Wang (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Illumina sequencing revealed roles of microRNAs in different aluminum tolerance of two citrus species - Yang-Fei Zhou; Yan-Yu Wang; Wei-Wei Chen; Li-Song Chen; Lin-Tong Yang (Physiology and Molecular Biology of Plants, 2020)

The effect of blastomere loss during frozen embryo transfer on the transcriptome of offspring’s umbilical cord blood - Yan-Ting Wu; Ze-Han Dong; Cheng Li; Dai-Zhan Zhou; Jun-Yu Zhang; Yan Wu; Jing-Jing Xu; Yu Wang; Xiao-Qun Ye; Jian-Zhong Sheng; Li Wang; He-Feng Huang (Molecular Biology Reports, 2020)

Synthesis and molecular docking studies of novel pyrimidine derivatives as potential antibacterial agents - Xue-Qian Bai; Chun-Shi Li; Ming-Yue Cui; Ze-Wen Song; Xing-Yu Zhou; Chao Zhang; Yang Zhao; Tian-Yi Zhang; Tie-Yan Jiang (Molecular Diversity, 2020)

Body weight, CYP2C19, and P2Y12 receptor polymorphisms relate to clopidogrel resistance in a cohort of Chinese ischemic stroke patients with aspirin intolerance - Zhiqiang Li; Wanqing Dong; Daorong Yang; Linhai Sun; Xianjun He; Huanhuan Hu; Jianping Zhang; Chunyu Wang; Yulin Li; Ming Zhao; Yu Kong; Yan Wang (European Journal of Clinical Pharmacology, 2020)

Characterization of a Protease Hyper-Productive Mutant of Bacillus pumilus by Comparative Genomic and Transcriptomic Analysis - Yong-Cheng Liu; Lin-Li Han; Tian-Yu Chen; Yan-Bing Lu; Hong Feng (Current Microbiology, 2020)

Bacillus tepidiphilus sp. nov., isolated from tepid spring - Manik Prabhu Narsing Rao; Zhou-Yan Dong; Yu Kan; Min Xiao; Ying Qian Kang; Wen-Jun Li (Archives of Microbiology, 2020)

Assessment of environmental microbial effects of insect-resistant transgenic Populus × euramericana cv. ‘74/76’ based on high-throughput sequencing - Jianmin Fan; Yan Dong; Xiaoyue Yu; Lizhu Yao; Dongmei Li; Jinmao Wang; Minsheng Yang (Acta Physiologiae Plantarum, 2020)

A pair of new neo -clerodane diterpenoid epimers from the roots of Croton crassifolius and their anti-inflammatory - Dong-Bo Zhang; Zhi-Shu Tang; Pei Xie; Yan-Ni Liang; Jin-Gao Yu; Zhen Zhang; Dong-Zhu Duan; Chun-Li Cui; Zhong-Xing Song; Li Ren; Zheng Wang; Dao-Geng Yu (Natural Product Research, 2020)

One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko - Wan-Rong Niu; Cong-Liang Guo; Deng-Ji Lou; Rui-Ting Li; Qiao Xiang; Yu-Lin Zou; Xiu-Ming Cui; Xiao-Yan Yang (Natural Product Research, 2020)

A new advance in the potential exposure to “old” and “new” halogenated flame retardants in the atmospheric environments and biota: From occurrence to transformation products and metabolites - Shengtao Ma; Yingxin Yu; Yan Yang; Guiying Li; Taicheng An (Critical Reviews in Environmental Science and Technology, 2020)

The CsGPA1-CsAQPs module is essential for salt tolerance of cucumber seedlings - Yan Yan; Mintao Sun; Yansu Li; Jun Wang; Chaoxing He; Xianchang Yu (Plant Cell Reports, 2020)

Anxiolytic Effect of Increased NREM Sleep after Acute Social Defeat Stress in Mice - Xiang Feng; Hui-Ying Zhao; Yu-Jin Shao; Hui-Fang Lou; Li-Ya Zhu; Shumin Duan; Yan-Qin Yu (Neuroscience Bulletin, 2020)
Social defeat stress (SDS) plays a major role in the pathogenesis of psychiatric disorders like anxiety and depression. Sleep is generally considered to involve recovery of the brain from prior experience during wakefulness and is altered after acute SDS. However, the effect of acute SDS on sleep/wake behavior in mice varies between studies. In addition, whether sleep changes in response to stress contribute to anxiety is not well established. Here, we first investigated the effects of acute SDS on sleep/wake states in the active period in mice. Our results showed that total sleep time (time in rapid eye-movement [REM] and non-REM [NREM] sleep) increased in the active period after acute SDS. NREM sleep increased mainly during the first 3 h after SDS, while REM sleep increased at a later time. Then, we demonstrated that the increased NREM sleep had an anxiolytic benefit in acute SDS. Mice deprived of sleep for 1 h or 3 h after acute SDS remained in a highly anxious state, while in mice with ad libitum sleep the anxiety rapidly faded away. Altogether, our findings suggest an anxiolytic effect of NREM sleep, and indicate a potential therapeutic strategy for anxiety.

Grape seed proanthocyanidin extract ameliorates hepatic lipid accumulation and inflammation in grass carp (Ctenopharyngodon idella) - Rong-Hua Lu; Chao-Bin Qin; Feng Yang; Wen-Ya Zhang; Yu-Ru Zhang; Guo-Kun Yang; Li-Ping Yang; Xiao-Lin Meng; Xiao Yan; Guo-Xing Nie (Fish Physiology and Biochemistry, 2020)

Occurrence and partitioning of brominated flame retardants (BFRs) in indoor air and dust: a 15-month case study in a test home - Jia-Qi Guo; Yong-feng Li; Li-Yan Liu; Chun-Yan Huo; Yu Sun; Wan-li Ma; Zi-feng Zhang; Yi-Fan Li (Environmental Science and Pollution Research, 2020)

Effects of biochar properties on the bioremediation of the petroleum-contaminated soil from a shale-gas field - Hong-Yang Ren; Zi-Jing Wei; Yan Wang; Yuan-Peng Deng; Ming-Yu Li; Bing Wang (Environmental Science and Pollution Research, 2020)

Optimal Selection of Sewage Treatment Technologies in Town Areas: A Coupled Multi-Criteria Decision-Making Model - Ben Liu; Jie Tang; Zhaoyang Li; Yu Yan; Jingshu Chen (Environmental Management, 2020)

Sodium Para-aminosalicylic Acid Reverses Changes of Glutamate Turnover in Manganese-Exposed Rats - Zhao-Cong Li; Fang Wang; Shao-Jun Li; Lin Zhao; Jun-Yan Li; Yue Deng; Xiao-Juan Zhu; Yu-Wen Zhang; Dong-Jie Peng; Yue-Ming Jiang (Biological Trace Element Research, 2020)

Psychroflexus maritimus sp. nov., isolated from coastal sediment - Yan-Lin Zhong; Rui Zhang; Xiao-Yu Zhang; Li-Xue Yu; Meng-Fan Zhao; Zong-Jun Du (Archives of Microbiology, 2020)

Numerical Simulation of a Polar Ship Moving in Level Ice Based on a One-Way Coupling Method - Bao-Yu Ni; Zi-Wang Chen; Kai Zhong; Xin-Ang Li; Yan-Zhuo Xue (Journal of Marine Science and Engineering, 2020)
In most previous ice–ship interaction studies involving fluid effects, ice was taken as unbreakable. Building breakable level ice on water domain is still a big challenge in numerical simulation. This paper overcomes this difficulty and presents a numerical modeling of a ship moving in level ice on the water by using a one-way CFD-DEM (computational fluid dynamics-discrete element method) coupling method. The detailed numerical processes and techniques are introduced. The ice crack propagation process including radial and circular cracks have been observed. Numerical results are compared with previous experimental data and good agreement has been achieved. The results show that water resistance is an order of magnitude smaller than ice resistance during the ice-breaking process. Ice resistance shows strong oscillation along with ice failure process, which are affected by ship speed and ice thickness significantly.

Adsorption and Desorption Characteristics of Vanadium (V) on Coexisting Humic Acid and Silica - Qiao-yu Song; Meng Liu; Juan Lu; Yu-liang Liao; Li Chen; Jin-yan Yang (Water, Air, & Soil Pollution, 2020)

Erratum to: Herbal decoctosome is a novel form of medicine - Xiaoyun Li; Zhu Liang; Jianchao Du; Zhiqing Wang; Song Mei; Zhiqing Li; Yan Zhao; Dandan Zhao; Yiming Ma; Jun Ye; Jiantao Xu; Yu Zhao; et al. (Science China Life Sciences, 2020)

Tyrosine Hydroxylase Gene Polymorphisms Contribute to Opioid Dependence and Addiction by Affecting Promoter Region Function - Jun-lin Liu; Shao-qing Li; Feng Zhu; Yu-xiang Zhang; Ya-nan Wu; Jing-si Yang; Bao Zhang; Chun-xia Yan (NeuroMolecular Medicine, 2020)

Retraction Note to: Ambient air pollution and adverse birth outcomes: a systematic review and meta-analysis - Le-qian Guo; Yu Chen; Bai-bing Mi; Shao-nong Dang; Dou-dou Zhao; Rong Liu; Hong-li Wang; Hong Yan (Journal of Zhejiang University-SCIENCE B, 2020)

Improving Fruit Coloration, Quality Attributes, and Phenolics Content in ‘Rainier’ and ‘Bing’ Cherries by Gibberellic Acid Combined with Homobrassinolide - Meng Li; Shunchang Cheng; Yan Wang; Yu Dong (Journal of Plant Growth Regulation, 2020)

Antiangiogenic effects of AG36, a triterpenoid saponin from Ardisia gigantifolia stapf. - Li-Hua Mu; Li-Hua Wang; Yu-Ning Wang; Ping Liu; Can Yan (Journal of Natural Medicines, 2020)

RETRACTED ARTICLE: A Fluorescent Zn(II) Coordination Polymer: Sensitive Detection of Cr2O72− in Water and Prevention Activity On the Deep Vein Thrombosis in Orthopedic Nursing - Yu Zhou; Li Cui; Yan Zhang; Yu Liu; Dai-Hong Ji (Journal of Fluorescence, 2020)

Identification of hypervirulent Klebsiella pneumoniae isolates using the string test in combination with Galleria mellonella infectivity - Gang Li; Jimin Shi; Yan Zhao; Yingzhou Xie; Yu Tang; Xiaofei Jiang; Yuan Lu (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Safe utilization and zoning on natural selenium-rich land resources: a case study of the typical area in Enshi County, China - Tao Yu; Wanling Hou; Qingye Hou; Wenjun Ma; Xueqi Xia; Yutong Li; Beizhan Yan; Zhongfang Yang (Environmental Geochemistry and Health, 2020)

Unexpected rise of ozone in urban and rural areas, and sulfur dioxide in rural areas during the coronavirus city lockdown in Hangzhou, China: implications for air quality - Liqiang Wang; Mengying Li; Shaocai Yu; Xue Chen; Zhen Li; Yibo Zhang; Linhui Jiang; Yan Xia; Jiali Li; Weiping Liu; Pengfei Li; Eric Lichtfouse; et al. (Environmental Chemistry Letters, 2020)

Contrary Roles of Wnt/β-Catenin Signaling in BMP9-Induced Osteogenic and Adipogenic Differentiation of 3T3-L1 Preadipocytes - Kailu Liang; Yu Du; Liang Chen; Liyuan Wang; Ruidong Li; Zhengjian Yan; Yang Liu (Cell Biochemistry and Biophysics, 2020)

Estimating purple-soil moisture content using Vis-NIR spectroscopy - Yu Gou; Jie Wei; Jin-lin Li; Chen Han; Qing-yan Tu; Chun-hong Liu (Journal of Mountain Science, 2020)

The effects of micro- and meso-scale characteristics on the mechanical properties of coal-bearing sandstone - Qiangling Yao; Liqiang Yu; Xuehua Li; Kai Yan; Qiang Xu; Weinan Wang; Chuanjin Tang (Arabian Journal of Geosciences, 2020)

Machine Learning-based Weather Support for the 2022 Winter Olympics - Jiangjiang Xia; Haochen Li; Yanyan Kang; Chen Yu; Lei Ji; Lve Wu; Xiao Lou; Guangxiang Zhu; Zaiwen Wang; Zhongwei Yan; Lizhi Wang; Jiang Zhu; et al. (Advances in Atmospheric Sciences, 2020)

Positive RT-PCR in urine from an asymptomatic patient with novel coronavirus 2019 infection: a case report - Jian-guo Ren; Dong-yan Li; Chang-fei Wang; Jian-hua Wu; Ying Wang; Yu-jing Sun; Qian Zhang; Yao-yong Wang; Xin-jian Chang (Infectious Diseases, 2020)

A fundamental theorem for eco-environmental surface modelling and its applications - Tianxiang Yue; Na Zhao; Yu Liu; Yifu Wang; Bin Zhang; Zhengping Du; Zemeng Fan; Wenjiao Shi; Chuanfa Chen; Mingwei Zhao; Dunjiang Song; Shihai Wang; et al. (Science China Earth Sciences, 2020)

Changes of plant community composition instead of soil nutrient status drive the legacy effects of historical nitrogen deposition on plant community N:P stoichiometry - Yan-Yu Hu; Hai-Wei Wei; Zhi-Wei Zhang; Shuang-Li Hou; Jun-Jie Yang; Jun-Feng Wang; Xiao-Tao Lü (Plant and Soil, 2020)

Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress - Yu Liu; Guang-Jing Zou; Bo-Xuan Tu; Zhao-Lan Hu; Cong Luo; Yan-Hui Cui; Yang Xu; Fang Li; Ru-Ping Dai; Fang-Fang Bi; Chang-Qi Li (Neurotoxicity Research, 2020)

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study - Shao-rui Hao; Ren Yan; Shan-yan Zhang; Jiang-shan Lian; Huan Cai; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Synergistic effects of pazopanib and hyperthermia against uterine leiomyosarcoma growth mediated by downregulation of histone acetyltransferase 1 - Chiao-Yun Lin; Angel Chao; Ren-Chin Wu; Li-Yu Lee; Shir-Hwa Ueng; Chia-Lung Tsai; Yun-Shien Lee; Meng-Ting Peng; Lan-Yan Yang; Huei-Jean Huang; Hsin-Shih Wang; Chyong-Huey Lai (Journal of Molecular Medicine, 2020)

Impaired peroxisomal fat oxidation induces hepatic lipid accumulation and oxidative damage in Nile tilapia - Yan Liu; Si-Lan Han; Yuan Luo; Ling-Yu Li; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2020)

Pseudorabies virus encephalitis in humans: a case series study - Siyuan Fan; Hongxun Yuan; Lei Liu; Hongfang Li; Shengnan Wang; Weili Zhao; Yihan Wu; Pei Wang; Yafang Hu; Jun Han; Yanli Lyu; Wuchao Zhang; et al. (Journal of NeuroVirology, 2020)

Isolation of Enterococcus faecium with Feeding Attractant Function from Pacific White Shrimp (Litopenaeus vannamei) Intestine - Yan Li; Chunyu Lu; Zhanqiao Yu; Qingshan Ma (Journal of Ocean University of China, 2020)

Gastric smooth muscle cells manifest an abnormal phenotype in Parkinson’s disease rats with gastric dysmotility - Xiao-Lin Xiu; Li-Fei Zheng; Xiao-Yu Liu; Yan-Yan Fan; Jin-Xia Zhu (Cell and Tissue Research, 2020)

Examining Health of Wetlands with Multiple Ecosystem Services as Targets in China’s Coastal Regions - Yangming Zhou; Yuehan Dou; Xiubo Yu; Li Zhang; Chong Huang; Yuyu Wang; Xiaowei Li; He Li; Yifei Jia; Martha Bakker; Gerrit Jan Carsjens; Yan Zhou; et al. (Chinese Geographical Science, 2020)

Lysinibacillus cavernae sp. nov., isolated from cave soil - Yu Kan; Xue-Ke Niu; Manik Prabhu Narsing Rao; Zhou-Yan Dong; Yuan-Guo Xie; Ying-Qian Kang; Wen-Jun Li (Archives of Microbiology, 2020)

Mesorhizobium rhizophilum sp. nov., a 1-aminocyclopropane-1-carboxylate deaminase producing bacterium isolated from rhizosphere of maize in Northeast China - Jun-lian Gao; Jing Xue; Yu-chen Sun; Han Xue; En Tao Wang; Hui Yan; Shuai Tong; Li-wei Wang; Xiuhai Zhang; Jian-guang Sun (Antonie van Leeuwenhoek, 2020)

Fluevirines E and F, two new alkaloids from Flueggea virosa - Xi Yang; Jianwen Liu; Zongqing Huo; Huansha Yuwen; Yan Li; Yu Zhang (Natural Product Research, 2020)

Correlation Between CCG Polymorphisms and CAG Repeats During Germline Transmission in Chinese Patients with Huntington’s Disease - Hong-Rong Cheng; Xiao-Yan Li; Hui-Li Yu; Miao Xu; Yan-Bin Zhang; Shi-Rui Gan; Hong-Lei Li; Zhi-Ying Wu (Neuroscience Bulletin, 2020)

Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort - Wei-Wei Li; Zhen Wang; Dong-Yu Fan; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Ling Li; Heng Yang; Yu-Hui Liu; Xian-Le Bu; Wang-Sheng Jin; Fan Zeng; et al. (Neuroscience Bulletin, 2020)

Sea-level changes controlled detrital sediment inputs to the Bicol Shelf in the western Philippine Sea since 150 ka - Zhishun Zhang; Fuqing Jiang; Tiegang Li; Dezhou Yang; Xiaojing Zhou; Zhifang Xiong; Xiaohua Qiu; Qi Jia; Yu Yan; Xuguang Feng (Journal of Oceanology and Limnology, 2020)

Phytochemical constituents of the pericarps of Illicium difengpi and their anti-inflammatory activity - De-Sheng Ning; Yu-Xia Fu; Li-Yan Peng; Hui Tang; Lian-Chun Li; Xing-De Wu; Yu-Song Huang; Zheng-Hong Pan (Natural Product Research, 2020)

A study on the effects of salinity and pH on PSII function in mulberry seedling leaves under saline–alkali mixed stress - Zhang Huihui; Li Xin; Che Yan-hui; Wang Yue; Li Ma-bo; Yang Rong-yi; Xu Nan; Sun Guang-yu (Trees, 2020)

Genome-wide identification of the NPR1-like gene family in Brassica napus and functional characterization of BnaNPR1 in resistance to Sclerotinia sclerotiorum - Zheng Wang; Lu-Yue Ma; Xiao Li; Feng-Yun Zhao; Rehman Sarwar; Jun Cao; Yu-Long Li; Li-Na Ding; Ke-Ming Zhu; Yan-Hua Yang; Xiao-Li Tan (Plant Cell Reports, 2020)

Development of a specific AFLP-based SCAR marker for Chinese Race 34MKG of Puccinia graminis f. sp. tritici - Si Chen; Xue Yang; Wen-gong Huang; Yan Liu; Ying Yu; Guang-wen Wu; Shu-quan Zhang; Tian-ya Li; Yuan-yin Cao (Molecular Biology Reports, 2020)

Characterization of a Rapeseed Anthocyanin-More Mutant with Enhanced Resistance to Sclerotinia sclerotiorum - Rui Liu; Li-Na Ding; Ming Li; Wei Cao; Yu-Kang Wang; Wei-Jie Wang; Yan-Kun Yu; Zheng Wang; Ke-Ming Zhu; Xiao-Li Tan (Journal of Plant Growth Regulation, 2020)

Sugar transporter genes in grass carp (Ctenopharyngodon idellus): molecular cloning, characterization, and expression in response to different stocking densities - Xiao Liang; Fengying Yan; Yu Gao; Mei Xiong; Haishan Wang; Kommaly Onxayvieng; Rong Tang; Li Li; Xi Zhang; Wei Chi; Marina Piria; Mirna Mrkonjić Fuka; et al. (Fish Physiology and Biochemistry, 2020)

Association between long-term exposure to Sulfur dioxide pollution and hypertension incidence in northern China: a 12-year cohort study - Mengfan Yan; Chaokang Li; Liwen Zhang; Xi Chen; Xueli Yang; Anqi Shan; Xuejun Li; Hui Wu; Zhao Ma; Yu Zhang; Pengyi Guo; Guanghui Dong; et al. (Environmental Science and Pollution Research, 2020)

The characteristics of oestrone mobility in water and soil by the addition of Ca-biochar and Fe–Mn-biochar derived from Litchi chinensis Sonn. - Huan-yu Tao; Hui Ge; Jianghong Shi; Xiaowei Liu; Wei Guo; Mengtao Zhang; Yaobin Meng; Xiao-yan Li (Environmental Geochemistry and Health, 2020)

Abnormal Galactosylated–Glycans recognized by Bandeiraea Simplicifolia Lectin I in saliva of patients with breast Cancer - Jiajun Yang; Xiawei Liu; Jian Shu; Yao Hou; Mengting Chen; Hanjie Yu; Tianran Ma; Haoqi Du; Jiaxu Zhang; Yan Qiao; Jianjun He; Lili Niu; et al. (Glycoconjugate Journal, 2020)

Influence of Aphis gossypii feeding on defense strategy of native and introduced populations of Ageratina adenophora - Ying Lin; Shu-Qi He; Zhi-Hui Lu; Yu-Lin Gao; Yan-Ru Duan; Zheng-Yue Li; Bin Chen; Fu-Rong Gui (Arthropod-Plant Interactions, 2020)

Tracing mantle sources in the northern Lau back-arc basin by independent component analysis of basalt isotopic compositions - Xichang Wu; Liyan Tian; Xuan-Ce Wang; Fengyou Chu; Quanshu Yan; Fengyue Sun; Xiaohu Li; Wei Wang; Luyao Yu; Zhenggang Li; Ling Chen (International Geology Review, 2020)

Design, synthesis and cholinesterase inhibitory activity of α -mangostin derivatives - Xiao-Qian Chi; Bo Hou; Liu Yang; Cheng-Ting Zi; Yong-Feng Lv; Jin-Yu Li; Fu-Cai Ren; Ming-Yan Yuan; Jiang-Miao Hu; Jun Zhou (Natural Product Research, 2020)

Iridoid, phenylethanoid and flavonoid glycosides from Forsythia suspensa - Qian Wei; Rong Zhang; Qin Wang; Xin Jia Yan; Quan Wei Yu; Fu Xia Yan; Chang Li; Yue Hu Pei (Natural Product Research, 2020)

Plant abiotic stress response and nutrient use efficiency - Zhizhong Gong; Liming Xiong; Huazhong Shi; Shuhua Yang; Luis R. Herrera-Estrella; Guohua Xu; Dai-Yin Chao; Jingrui Li; Peng-Yun Wang; Feng Qin; Jijang Li; Yanglin Ding; et al. (Science China Life Sciences, 2020)

Building a sequence map of the pig pan-genome from multiple de novo assemblies and Hi-C data - Xiaomeng Tian; Ran Li; Weiwei Fu; Yan Li; Xihong Wang; Ming Li; Duo Du; Qianzi Tang; Yudong Cai; Yiming Long; Yue Zhao; Mingzhou Li; et al. (Science China Life Sciences, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

Role of T-type Calcium Channels in Generating Hyperexcitatory Behaviors during Emergence from Sevoflurane Anesthesia in Neonatal Rats - Feng-Yan Shen; Byung-Gun Lim; Wen Wen; Yu Zhang; Bo Cao; Yue-Guang Si; Li-Qing Ma; Meng Deng; Yang In Kim; Young-Beom Kim; Ying-Wei Wang (Neuroscience Bulletin, 2020)

Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure - Jiang-shan Lian; Huan Cai; Shao-rui Hao; Xi Jin; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Shan-yan Zhang; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Investigation of influence of baffles on landslide debris mobility by 3D material point method - Xinpo Li; Qiwei Yan; Shuxi Zhao; Yu Luo; Yong Wu; Dongpo Wang (Landslides, 2020)

Biocontrol potential of Bacillus subtilis IBFCBF-4 against Fusarium wilt of watermelon - Jiuxiang Zhu; Taimeng Tan; Airong Shen; Xiebin Yang; Yongting Yu; Chunsheng Gao; Zhimin Li; Yi Cheng; Jia Chen; Litao Guo; Xiangping Sun; Zhun Yan; et al. (Journal of Plant Pathology, 2020)

Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients - Huan-Yu Meng; Xi Li; Wan-Lin Jin; Cheng-Kai Yan; Xiao-Hua Dong; Qiu Xu; Yu-Yao Peng; Zhi-Bin Li; Yi Li; Zhao-Hui Luo; Li-Qun Xu; Huan Yang (European Journal of Clinical Pharmacology, 2020)

Illumina MiSeq sequencing and network analysis the distribution and co-occurrence of bacterioplankton in Danjiangkou Reservoir, China - Zhao-Jin Chen; Ge Xu; Chuan-Yu Ding; Bao-Hai Zheng; Yan Chen; Hui Han; Yu-Ying Li; Jian-Wei Shi; Lan-Qun Hu (Archives of Microbiology, 2020)

SP94 Peptide-Functionalized PEG-PLGA Nanoparticle Loading with Cryptotanshinone for Targeting Therapy of Hepatocellular Carcinoma - Xiaoling Nie; Yuan Liu; Ming Li; Xuesong Yu; Wanwen Yuan; Sixi Huang; Di Ren; Ying Wang; Yan Wang (AAPS PharmSciTech, 2020)

The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line - Gen-Meng Yang; Lu Li; Feng-Lin Xue; Chen-Li Ma; Xiao-Feng Zeng; Yong-Na Zhao; Dong-Xian Zhang; Yang Yu; Qian-Wen Yan; Yi-Qing Zhou; Shi-Jun Hong; Li-Hua Li (Neurotoxicity Research, 2020)

Metabolomic abnormalities of purine and lipids implicated olfactory bulb dysfunction of CUMS depressive rats - Yong He; Yue Wang; Zhonghao Wu; Tianlan Lan; Yu Tian; Xi Chen; Yan Li; Ruozhi Dang; Mengge Bai; Ke Cheng; Peng Xie (Metabolic Brain Disease, 2020)

A novel noncontact detection method of surgeon’s operation for a master-slave endovascular surgery robot - Yan Zhao; Huiming Xing; Shuxiang Guo; Yuxin Wang; Jinxin Cui; Youchun Ma; Yu Liu; Xinke Liu; Junqiang Feng; Youxiang Li (Medical & Biological Engineering & Computing, 2020)

Correction to: AVE0991, a nonpeptide angiotensin-(1–7) mimic, inhibits angiotensin II–induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice - Hui Ma; Yu-Lin Wang; Nai-Hao Hei; Jun-Long Li; Xin-Ran Cao; Bo Dong; Wen-jiang Yan (Journal of Molecular Medicine, 2020)

AVE0991, a nonpeptide angiotensin-(1–7) mimic, inhibits angiotensin II–induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice - Hui Ma; Yu-Lin Wang; Nai-Hao Hei; Jun-Long Li; Xin-Ran Cao; Bo Dong; Wen-jiang Yan (Journal of Molecular Medicine, 2020)

Transient Forebrain Ischemia Induces Differential Bdnf Transcript Expression and Histone Acetylation Patterns in the Rat Hippocampus - Jianguo Li; Deping Yan; Na Ma; Jing Chen; Xin Zhao; Yu Zhang; Ce Zhang (Journal of Molecular Neuroscience, 2020)

Effects of small nucleolar RNA SNORD44 on the proliferation, apoptosis and invasion of glioma cells - Xian-Ru Xia; Wen-Cui Li; Zong-Tao Yu; Jie Li; Chun-Yan Peng; Li Jin; Guo-Lin Yuan (Histochemistry and Cell Biology, 2020)

Lipocalin-2 Predicts Long-Term Outcome of Normotensive Patients with Acute Pulmonary Embolism - Haixu Yu; Zhuohui Liu; Jie Lu; Xinying Yang; Xin-Xin Yan; Yuhong Mi; Lu Hua; Yulin Li; Zhi-Cheng Jing; Jie Du (Cardiovascular Toxicology, 2020)

Interannual Variability and Scenarios Projection of Sea Ice in Bohai Sea Part I: Variation Characteristics and Interannual Hindcast - Yan Jiao; Fei Huang; Qingrong Liu; Ge Li; Yaru Li; Qingxi Yu; Yiding Zhao (Journal of Ocean University of China, 2020)

Identification and differential expression analysis of anthocyanin biosynthetic genes in root-skin color variants of radish (Raphanus sativus L.) - Rugang Yu; Xueling Du; Jing Li; Lan Liu; Chaomeng Hu; Xiaoling Yan; Yuqing Xia; Huijuan Xu (Genes & Genomics, 2020)

Coix seed oil prolongs lifespan and enhances stress resistance in Caenorhabditis elegans - Xin-Yan Chen; De-Chun Liao; Ying-Ting Yu; Cong-Min Wei; Ling-Yan Xuan; Shan Li; Hong-Bing Wang (Biogerontology, 2020)

Potent antitumor activity of oncolytic adenovirus expressing C/EBPβ against hepatocellular carcinoma - Yan Zeng; Feng-di Li; Jiang-long Du; Yu-jia Xue; Jing Liu; Xin Cao; Hai-zhen Wang (Apoptosis, 2020)

Litorilituus lipolyticus sp. nov., isolated from intertidal sand of the Yellow Sea in China, and emended description of Colwellia asteriadis - Ang Liu; Yan-Jiao Zhang; Qing-Jie Xue; Hui Wang; Yuan-Yuan Yang; Feng Du; Long-Yu Zhao; Hong-Hua Zhang; Yun-Qing Li; Xiu-Zhen Li (Antonie van Leeuwenhoek, 2020)

Common Variant in TREM1 Influencing Brain Amyloid Deposition in Mild Cognitive Impairment and Alzheimer’s Disease - Yue-Song Liu; Wen-Jing Yan; Chen-Chen Tan; Jie-Qiong Li; Wei Xu; Xi-Peng Cao; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2020)

Microbial communities present on mooring chain steels with different copper contents and corrosion rates - Jiajia Wu; Jieyan Gao; Dun Zhang; Faqi Tan; Jiang Yin; Yu Wang; Yan Sun; Ee Li (Journal of Oceanology and Limnology, 2020)

Tumor necrosis factor-alpha (TNF-α) in spotted halibut Verasper variegatus at the embryonic and metamorphic stages - Zan Li; Xiumei Liu; Xinxin Du; Kai Zhang; Yan Chen; Xubo Wang; Zhigang Wang; Haiyang Yu; Quanqi Zhang (Journal of Oceanology and Limnology, 2020)

Antibiotics in wastewater from multiple sources and surface water of the Yangtze River in Chongqing in China - Yungang Shi; Jialie Liu; Li Zhuo; Xiao Yan; Fengshan Cai; Weikeng Luo; Mingzhong Ren; Qiang Liu; Yunjiang Yu (Environmental Monitoring and Assessment, 2020)

Comparative genomics analysis of Nitriliruptoria reveals the genomic differences and salt adaptation strategies - Dai-Di Chen; Ye Tian; Jian-Yu Jiao; Xiao-Tong Zhang; Yong-Guang Zhang; Zhou-Yan Dong; Meng-Jie Xiong; Min Xiao; Wen-Sheng Shu; Wen-Jun Li (Extremophiles, 2020)

A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus - Yan Wang; Xuejiao Cui; Xu Chen; Shixing Yang; Yu Ling; Qianben Song; Su Zhu; Luying Sun; Chuang Li; Yu Li; Xutao Deng; Eric Delwart; et al. (Archives of Virology, 2020)

Pedobacter indicus sp. nov., isolated from deep-sea sediment - Xiao-yan He; Na Li; Xiu-lan Chen; Yu-zhong Zhang; Xi-ying Zhang; Xiao-yan Song (Antonie van Leeuwenhoek, 2020)

Identification and characterization of circular RNAs during wood formation of poplars in acclimation to low nitrogen availability - Huimin Liu; Wanwen Yu; Jiangting Wu; Zhuorong Li; Hui Li; Jing Zhou; Jingjing Hu; Yan Lu (Planta, 2020)

Ketamine Alleviates Fear Generalization Through GluN2B-BDNF Signaling in Mice - Muhammad Asim; Bo Hao; Yu-Han Yang; Bu-Fang Fan; Li Xue; Yan-Wei Shi; Xiao-Guang Wang; Hu Zhao (Neuroscience Bulletin, 2020)

Disruption of tight junction structure contributes to secretory dysfunction in IgG4-related sialadenitis - Sai-Nan Min; Li-Ling Wu; Yan-Yan Zhang; Wen-Xuan Zhu; Xin Cong; Guang-Yan Yu (Journal of Molecular Histology, 2020)

Synergism of citric acid and zero-valent iron on Cr(VI) removal from real contaminated soil by electrokinetic remediation - Yi Zheng; Yujie Yan; Lin Yu; Huilin Li; Binquan Jiao; YanChyuan Shiau; Dongwei Li (Environmental Science and Pollution Research, 2020)

The false smut pathogen Ustilaginoidea virens requires rice stamens for false smut ball formation - Jing Fan; Jie Liu; Zhi‐You Gong; Pei‐Zhou Xu; Xiao‐Hong Hu; Jin‐Long Wu; Guo‐Bang Li; Juan Yang; Yu‐Qiu Wang; Yu‐Feng Zhou; Shuang‐Cheng Li; Li Wang; et al. (Environmental Microbiology, 2020)
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The disease is characterized by the transformation of individual rice florets into false smut balls, which is caused by the fungal pathogen Ustilaginoidea virens . To date, little is known about the host factors required for false smut ball formation by U . virens . In this study, we identified histological determinants for the formation of false smut balls by inoculating U . virens into rice floral mutants defective with respect to individual floral parts. The results showed that U . virens could form mature false smut balls in rice floral mutants with defective pistils, but failed to develop false smut balls in the superwoman mutant lacking stamens, identifying that U . virens requires rice stamens to complete its infection cycle. Comparative transcriptome analysis indicated a list of candidate host genes that may facilitate nutrient acquisition by U . virens from the rice stamens, such as SWEET11 , SWEET14 and SUT5 , and genes involved in the biosynthesis of trehalose and raffinose family sugars. These data pinpoint rice stamens as the key target organ of U . virens infection and provide a valuable starting point for dissecting the molecular mechanism of false smut ball formation.

Aeroplane detection from high-resolution remotely sensed imagery using bag-of-visual-words based hough forests - Yongtao Yu; Yan Yuan; Haiyan Guan; Dilong Li; Tiannan Gu (International Journal of Remote Sensing, 2020)

Legacy effects of nitrogen deposition on plant nutrient stoichiometry in a temperate grassland - Yan-Yu Hu; Seeta Sistla; Hai-Wei Wei; Zhi-Wei Zhang; Shuang-Li Hou; Jun-Jie Yang; Zheng-Wen Wang; Jun-Feng Wang; Xiao-Tao Lü (Plant and Soil, 2020)

Agrobacterium-mediated genetic transformation of Chinese chestnut (Castanea mollissima Blume) - Zhi-lin Sun; Xiao Li; Wan Zhou; Jun-di Yan; Yue-rong Gao; Xiao-wei Li; Jia-chen Sun; Ke-feng Fang; Qing Zhang; Yu Xing; Ling Qin; Qing-qin Cao (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)
Chinese chestnut ( Castanea mollissima ) is an important germplasm resource for the breeding of Castanea species worldwide with vital ecological and economic value. Biotechnology overcomes the limitations of traditional breeding and accelerates germplasm improvement. However, a genetic transformation system for Chinese chestnut has not yet been established. In this study, a stable and efficient Agrobacterium -mediated genetic transformation method for Chinese chestnut is described. Embryogenic calli of C. mollissima cv. ‘Yanshanhongli’ were used as the target material. The sensitivity of embryogenic calli to kanamycin was determined, whereby the proliferation of non-transformed calli was completely inhibited at 180 mg/L. Antibiotic inhibition results for Chinese chestnut embryogenic calli showed that 50 mg/L cefotaxime and 500 μM timentin completely inhibited the growth of Agrobacterium tumefaciens but did not affect the normal growth of Chinese chestnut embryogenic calli. When embryogenic calli were co-cultured for 2 days with Agrobacterium tumefaciens strain AGL1 harboring the PBI121-EGFP plasmid, an embryogenic callus transformation efficiency of 4.55% was obtained, and two transgenic chimera were acquired. This Agrobacterium -mediated transformation system for Chinese chestnut provides a fundamental platform for genetic improvement of core germplasm and for further verification of gene function.

Characterizing the spatial distribution of typical natural disaster vulnerability in China from 2010 to 2017 - Qian Wang; Qi-peng Zhang; Yang-yang Liu; Lin-jing Tong; Yan-zhen Zhang; Xiao-yu Li; Jian-long Li (Natural Hazards, 2020)

Mechanism of CNP-mediated DG-PKC and IP4 signaling pathway in diabetic rats with gastric motility disorder - Hui-Ming Lian; Jun-Yu Guo; Yan Sun; Mo-Han Zhang; Li-Hua Piao; Zheng Jin; Ying-Lan Cai (Molecular Biology Reports, 2020)

Soil particle-size distribution and aggregate stability of new reconstructed purple soil affected by soil erosion in overland flow - Feng-Lin Zuo; Xiao-Yan Li; Xiao-Fan Yang; Yang Wang; Yu-Jun Ma; Yu-Han Huang; Chao-Fu Wei (Journal of Soils and Sediments, 2020)

Genome-wide identification and prediction of long non-coding RNAs in half-smooth tongue sole Cynoglossus semilaevis - Xiaoli Jiang; Xiaohong Jing; Yan Lü; Changmin Shan; Jiahua Li; Yan Yu; Yuyong Wu; Yeying Sun (Journal of Oceanology and Limnology, 2020)

Evaluation of the genetic diversity of mango (Mangifera indica L.) seedling germplasm resources and their potential parents with start codon targeted (SCoT) markers - Li Zhou; Xin-Hua He; Hai-Xia Yu; Mei-Yan Chen; Yan Fan; Xiu-Juan Zhang; Zhong-Bing Fang; Cong Luo (Genetic Resources and Crop Evolution, 2020)

Controlled Release of Spirotetramat Using Starch–Chitosan–Alginate-Encapsulation - Yan-Li Xie; Wayne Jiang; Fen Li; Yu Zhang; Xiao-Yu Liang; Meng Wang; Xueqing Zhou; Shao-Ying Wu; Cheng-Hui Zhang (Bulletin of Environmental Contamination and Toxicology, 2020)

Deltamethrin Impairs Honeybees (Apis mellifera) Dancing Communication - Zu Yun Zhang; Zhen Li; Qiang Huang; Xue Wen Zhang; Li Ke; Wei Yu Yan; Li Zhen Zhang; Zhi Jiang Zeng (Archives of Environmental Contamination and Toxicology, 2020)

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages - Di Chen; Xiang-Yu Xu; Rui Li; Gen-Ao Zang; Yue Zhang; Ming-Rui Wang; Meng-Fei Xiong; Jia-Rui Xu; Ting Wang; Hui Fu; Qin Hu; Bin Wu; et al. (AAPS PharmSciTech, 2020)

Trends in summer heatwaves in central Asia from 1917 to 2016: Association with large‐scale atmospheric circulation patterns - Shuang Yu; Zhongwei Yan; Nicolas Freychet; Zhen Li (International Journal of Climatology, 2020)
The changes in the frequency, duration, and intensity of summer heatwaves over central Asia during the period 1917–2016 were studied. On average, the frequency, duration, and intensity of heatwaves showed significant positive trends during the period 1917–2016, with enhanced rates during the last 50 years. During 1967–2016, the heatwave indices increased significantly in most of central Asia, especially in the western part. The number of heatwaves has increased by 1.3 times since the 1960s. Remarkable changes in the frequency and duration of heatwaves occurred during the 1990s in association with the inter‐decadal shift in the Silk Road pattern of atmospheric circulation around 1997. The results based on the ERA‐Interim reanalysis data set were well‐matched with the station observations during the period 1979–2016, whereas those based on the NCEP‐NCAR data set were less well matched. Heatwaves in central Asia were closely related to a zonal wave circulation pattern at 500 hPa with a centre of positive geopotential height anomalies over central Asia. This anomalous circulation pattern was rapidly enhanced during the 1990s, suggesting that large‐scale patterns of atmospheric circulation had a role in modulating the occurrence of heatwaves in central Asia.

Physiological functions of urea transporter B - Lanying Yu; Tiantian Liu; Shuang Fu; Li Li; Xiaoping Meng; Xin Su; Zhanfeng Xie; Jiayan Ren; Yan Meng; Xuejiao Lv; Yanwei Du (Pflügers Archiv - European Journal of Physiology, 2019)
Urea transporters (UTs) are membrane proteins in the urea transporter protein A (UT-A) and urea transporter protein B (UT-B) families. UT-B is mainly expressed in endothelial cell membrane of the renal medulla and in other tissues, including the brain, heart, pancreas, colon, bladder, bone marrow, and cochlea. UT-B is responsible for the maintenance of urea concentration, male reproductive function, blood pressure, bone metabolism, and brain astrocyte and cardiac functions. Its deficiency and dysfunction contribute to the pathogenesis of many diseases. Actually, UT-B deficiency increases the sensitivity of bladder epithelial cells to apoptosis triggers in mice and UT-B-null mice develop II-III atrioventricular block and depression. The expression of UT-B in the rumen of cow and sheep may participate in digestive function. However, there is no systemic review to discuss the UT-B functions. Here, we update research approaches to understanding the functions of UT-B.

Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia - Liansheng Zhao; Huijuan Wang; Yamin Zhang; Jinxue Wei; Peiyan Ni; Hongyan Ren; Gang Li; Qiang Wang; Gavin P Reynolds; Weihua Yue; Wei Deng; Hao Yan; et al. (Neuroscience Bulletin, 2019)

Characteristics and Prognosis of Talaromyces marneffei Infection in Non-HIV-Infected Children in Southern China - Jing Guo; Bing-Kun Li; Tian-Min Li; Fang-Lin Wei; Yu-Jiao Fu; Yan-Qing Zheng; Kai-Su Pan; Chun-Yang Huang; Cun-Wei Cao (Mycopathologia, 2019)

The Rho kinase inhibitor fasudil attenuates Aβ1–42-induced apoptosis via the ASK1/JNK signal pathway in primary cultures of hippocampal neurons - Ye Gao; Yuqing Yan; Qingli Fang; Nianping Zhang; Gajendra Kumar; Jihong Zhang; Li-Juan Song; Jiezhong Yu; Linhu Zhao; Han-Ting Zhang; Cun-Gen Ma (Metabolic Brain Disease, 2019)

Metabolomic profiling on rat brain of prenatal malnutrition: implicated for oxidative stress and schizophrenia - Fei Xu; Xin Li; Weibo Niu; Gaini Ma; Qianqian Sun; Yan Bi; Zhenming Guo; Decheng Ren; Jiaxin Hu; Fan Yuan; Ruixue Yuan; Lei Shi; et al. (Metabolic Brain Disease, 2019)

Short hairpin RNAs targeting M and N genes reduce replication of porcine deltacoronavirus in ST cells - Wen-yuan Gu; Yan Li; Bao-jing Liu; Jing Wang; Guang-fu Yuan; Shao-jie Chen; Yu-Zhu Zuo; Jing-Hui Fan (Virus Genes, 2019)

The complete chloroplast genome of the daimyo oak, Quercus dentata Thunb. - Hua-Lei Hu; Jing-Yu Zhang; Yu-Ping Li; Lu Xie; Dong-Bin Chen; Qun Li; Yan-Qun Liu; Shu-Rong Hui; Li Qin (Conservation Genetics Resources, 2019)