Long-term changes of water acidity in an intact forested watershed in south China - Xiao-dong Liu; Ying-jie Feng; Qi-feng Mo; Guo-wei Chu; Yue-lin Li; Qian-mei Zhang; Wei-qiang Zhang; Xian-hua Gan; Qing Zhou (Journal of Mountain Science, 2021)

Mitochondrial Genome of Episesarma lafondii (Brachyura: Sesarmidae) and Comparison with Other Sesarmid Crabs - Ying Zhang; Yan Gao; Li Gong; Xinting Lu; Lihua Jiang; Bingjian Liu; Liqin Liu; Zhenming Lü; Pengfei Li (Journal of Ocean University of China, 2021)

Evaluation of four artificial diets on demography parameters of Neoseiulus barkeri - Ya-Ying Li; Jin-Ge Yuan; Ming-Xiu Liu; Zi-Hui Zhang; Hai-Wei Zhou; Huai Liu (BioControl, 2021)

Enhanced expression of DNA methyltransferase 1-associated protein1 gene thermotolerance in a high-temperature acclimated predatory mite Neoseiulus barkeri - Ya-Ying Li; Chuan-Bei Tian; Yi-Xia Wu; Tian-Di Niu; Hao Wang; Wen-Hui Fan; Huai Liu (BioControl, 2021)

Three new diterpenoids from Euphorbia peplus - Yan-Ni Chen; Qing-Yun Lu; Dong-Mei Li; Ying-Yao Li; Xue-Xue Pu; Bo-Ting Li; Xiao-Han Tang; Hong-Yu Tang; Shuai Liu; Lei Yang; Yu Zhang; Ying-Tong Di; et al. (Natural Product Research, 2021)

Two new alkaloids from the sepals of Solanum melongena L - Dong-Ying Zhao; Yan Liu; Xin Yin; Xiao-Mao Li; Juan Pan; Wei Guan; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2021)

Genomic characterization of a rare Carica papaya X chromosome mutant reveals a candidate monodehydroascorbate reductase 4 gene involved in all-hermaphrodite phenomenon - Jen-Ren Chen; Hiroki Ueno; Hideo Matsumura; Naoya Urasaki; Chen-Yu Lee; Fure-Chyi Chen; Shih-Wen Chin; Chun-Chi Liu; Chan-Tai Chiu; Kazuhiko Tarora; Jing-Yi Li; Chieh Ying Lee; et al. (Molecular Genetics and Genomics, 2021)

Biomarker responses and histological damage in the gill, liver, and gonad of Cyprinus carpio with benzo(a)pyrene exposure - Weilai Sha; Fengsen Cai; Yu Li; Ying Wang; Chunchen Liu; Renjun Wang; Peike Gao (Environmental Science and Pollution Research, 2021)

Terpenoid indole alkaloid biosynthesis in Catharanthus roseus: effects and prospects of environmental factors in metabolic engineering - Yongliang Liu; Barunava Patra; Sanjay Kumar Singh; Priyanka Paul; Yan Zhou; Yongqing Li; Ying Wang; Sitakanta Pattanaik; Ling Yuan (Biotechnology Letters, 2021)
Plants synthesize a vast array of specialized metabolites that primarily contribute to their defense and survival under adverse conditions. Many of the specialized metabolites have therapeutic values as drugs. Biosynthesis of specialized metabolites is affected by environmental factors including light, temperature, drought, salinity, and nutrients, as well as pathogens and insects. These environmental factors trigger a myriad of changes in gene expression at the transcriptional and posttranscriptional levels. The dynamic changes in gene expression are mediated by several regulatory proteins that perceive and transduce the signals, leading to up- or down-regulation of the metabolic pathways. Exploring the environmental effects and related signal cascades is a strategy in metabolic engineering to produce valuable specialized metabolites. However, mechanistic studies on environmental factors affecting specialized metabolism are limited. The medicinal plant Catharanthus roseus (Madagascar periwinkle) is an important source of bioactive terpenoid indole alkaloids (TIAs), including the anticancer therapeutics vinblastine and vincristine. The emerging picture shows that various environmental factors significantly alter TIA accumulation by affecting the expression of regulatory and enzyme-encoding genes in the pathway. Compared to our understanding of the TIA pathway in response to the phytohormone jasmonate, the impacts of environmental factors on TIA biosynthesis are insufficiently studied and discussed. This review thus focuses on these aspects and discusses possible strategies for metabolic engineering of TIA biosynthesis. Purpose of work Catharanthus roseus is a rich source of bioactive terpenoid indole alkaloids (TIAs). The objective of this work is to present a comprehensive account of the influence of various biotic and abiotic factors on TIA biosynthesis and to discuss possible strategies to enhance TIA production through metabolic engineering.

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

Bacterial Viruses Subcommittee and Archaeal Viruses Subcommittee of the ICTV: update of taxonomy changes in 2021 - Mart Krupovic; Dann Turner; Vera Morozova; Mike Dyall-Smith; Hanna M. Oksanen; Rob Edwards; Bas E. Dutilh; Susan M. Lehman; Alejandro Reyes; Diana P. Baquero; Matthew B. Sullivan; Jumpei Uchiyama; et al. (Archives of Virology, 2021)
In this article, we – the Bacterial Viruses Subcommittee and the Archaeal Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) – summarise the results of our activities for the period March 2020 – March 2021. We report the division of the former Bacterial and Archaeal Viruses Subcommittee in two separate Subcommittees, welcome new members, a new Subcommittee Chair and Vice Chair, and give an overview of the new taxa that were proposed in 2020, approved by the Executive Committee and ratified by vote in 2021. In particular, a new realm, three orders, 15 families, 31 subfamilies, 734 genera and 1845 species were newly created or redefined (moved/promoted).

Novel Alcaligenes ammonioxydans sp. nov. from wastewater treatment sludge oxidizes ammonia to N 2 with a previously unknown pathway - Meng‐Ru Wu; Ting‐Ting Hou; Ying Liu; Li‐Li Miao; Guo‐Min Ai; Lan Ma; Hai‐Zhen Zhu; Ya‐Xin Zhu; Xi‐Yan Gao; Craig W. Herbold; Michael Wagner; De‐Feng Li; et al. (Environmental Microbiology, 2021)
Summary Heterotrophic nitrifiers are able to oxidize and remove ammonia from nitrogen‐rich wastewaters but the genetic elements of heterotrophic ammonia oxidation are poorly understood. Here, we isolated and identified a novel heterotrophic nitrifier, Alcaligenes ammonioxydans sp. nov. strain HO‐1, oxidizing ammonia to hydroxylamine and ending in the production of N 2 gas. Genome analysis revealed that strain HO‐1 encoded a complete denitrification pathway but lacks any genes coding for homologous to known ammonia monooxygenases or hydroxylamine oxidoreductases. Our results demonstrated strain HO‐1 denitrified nitrite (not nitrate) to N 2 and N 2 O at anaerobic and aerobic conditions respectively. Further experiments demonstrated that inhibition of aerobic denitrification did not stop ammonia oxidation and N 2 production. A gene cluster ( dnfT1RT2ABCD ) was cloned from strain HO‐1 and enabled E . coli accumulated hydroxylamine. Sub‐cloning showed that genetic cluster dnfAB or dnfABC already enabled E . coli cells to produce hydroxylamine and further to 15 N 2 from ( 15 NH 4 ) 2 SO 4 . Transcriptome analysis revealed these three genes dnfA , dnfB and dnfC were significantly upregulated in response to ammonia stimulation. Taken together, we concluded that strain HO‐1 has a novel dnf genetic cluster for ammonia oxidation and this dnf genetic cluster encoded a previously unknown pathway of di rect amm onia ox idation (Dirammox) to N 2 .

Analysis of the Spatial and Temporal Variation of Sea Ice and Connectivity in the NEP of the Arctic in Summer in Hot Years - Guochong Liu; Min Ji; Fengxiang Jin; Ying Li; Yawen He; Ting Li (Journal of Marine Science and Engineering, 2021)
Climate warming has enabled the Arctic region to achieve seasonal navigation, and sea ice concentration is an important factor affecting the navigation of the Arctic waterways. This article uses the Arctic sea ice concentration data of the three highest temperatures in 2016, 2019, and 2020, combined with the Arctic summer sea level pressure, wind field, temperature, temperature anomaly, ice age, and sea ice movement data to analyze the spatial and temporal variation of sea ice and connectivity in the Northeast Passage (NEP) of the Arctic in Summer in three hot years, and summarizes the causes of sea ice anomalies. The results show that: (1) the summer Arctic sea ice extent in 2016, 2019 and 2020 were all lower than the multi-year average sea ice extent, and the summer sea ice extent in 2020 had the largest change trend; (2) in October of these three years, the sea ice was all negative anomalies, extending the opening time of the NEP; (3) when the sea ice concentration was 30% as the threshold, the navigation period of the NEP in 2016 was from mid-August to late October, 2019 was from the beginning of August to mid-October, 2020 was from the end of July to the end of October, and 2020 was the longest year since the opening of the NEP; (4) when the sea ice concentration was 10% as the threshold, the navigation period of the NEP in 2016 was from the end of August to the end of October, 2019 was from early August to mid-October, and 2020 was from the beginning of August to the end of October; (5) the key navigable areas of the NEP in the past three years were the central waters of the East Siberian Sea, the New Siberian Islands and the Vilkitsky Strait; (6) the navigation period of the NEP in 2016, 2019 and 2020 was longer. The main reasons were that the temperature of the NEP in the past 3 years was relatively high, the wind was weak, the sea ice movement had little effect, and the sea ice age in the key navigable areas was first year ice, which was easy to melt, which greatly promoted the opening of the NEP.

Screening and identification of salt-tolerance genes in Sophora alopecuroides and functional verification of SaAQP - Youcheng Zhu; Qingyu Wang; Wenyun Guo; Ziwei Gao; Ying Wang; Yang Xu; Yajing Liu; Zhipeng Ma; Fan Yan; Jingwen Li (Planta, 2021)

Genome-wide analysis and characterization of R2R3-MYB family in pigeon pea (Cajanus cajan) and their functional identification in phenylpropanoids biosynthesis - Jie Yang; Su Zhang; Hongquan Li; Litao Wang; Ying Liu; Lili Niu; Qing Yang; Dong Meng; Yujie Fu (Planta, 2021)

Long-term copper exposure promotes apoptosis and autophagy by inducing oxidative stress in pig testis - Yuanliang Li; Hanming Chen; Jianzhao Liao; Keli Chen; Muhammad Tariq Javed; Na Qiao; Qiwen Zeng; Bingxian Liu; Jiangnan Yi; Zhaoxin Tang; Ying Li (Environmental Science and Pollution Research, 2021)

Effects of crab disturbance on nitrogen migration and transformation in a coastal tidal flat wetland - Jinli Li; Guofen Hua; Shangqing Liu; Xiangdong Liu; Yuying Huang; Ying Shi (Environmental Science and Pollution Research, 2021)

Structural and Functional Characteristics of Microplastic Associated Biofilms in Response to Temporal Dynamics and Polymer Types - Chen Tu; Ying Liu; Lianzhen Li; Yuan Li; Angela Vogts; Yongming Luo; Joanna J. Waniek (Bulletin of Environmental Contamination and Toxicology, 2021)

Molecular characterization of a porcine sapelovirus strain isolated in China - Nana Li; Jie Tao; Benqiang Li; Jinghua Cheng; Ying Shi; Shi Xiaohui; Huili Liu (Archives of Virology, 2021)

Imaging and clinical features of cervical artery web: report of 41 cases and literature review - Minghui Wang; Ruizhi Zhou; Han Zhao; Lei Niu; Song Liu; Ying Li; Xuejun Liu (Acta Neurologica Belgica, 2021)

Geniposide-Loaded Liposomes for Brain Targeting: Development, Evaluation, and In Vivo Studies - Jinyan Wan; Yu Long; Songyu Liu; Yulu Zhang; Yan Xiang; Dan Li; Ai Shi; Yu Shuang; Ying Li; Yanan He; Nan Li; Yongmei Guan (AAPS PharmSciTech, 2021)

Two new norsesquiterpenoids with estrogenic activity from the stems and leaves of Dioscorea oppositifolia L - Ying-Jie Ren; Yan-Gang Cao; Meng-Nan Zeng; Bei-Bei Zhang; Yan-Ling Liu; Meng-Na Wang; Yan-Li Zhang; Wei-Sheng Feng; Xiao-Ke Zheng (Natural Product Research, 2021)

Chemical constituents from Urtica fissa stem and their inhibitory effects on α -glucosidase activity - Ying Zhang; Jinzhao Liu; Zixian Guo; Xiaobo Li; Mengyue Wang (Natural Product Research, 2021)

Reduced Firing of Nucleus Accumbens Parvalbumin Interneurons Impairs Risk Avoidance in DISC1 Transgenic Mice - Xinyi Zhou; Bifeng Wu; Wenhao Liu; Qian Xiao; Wei He; Ying Zhou; Pengfei Wei; Xu Zhang; Yue Liu; Jie Wang; Jufang He; Zhigang Zhang; et al. (Neuroscience Bulletin, 2021)
A strong animal survival instinct is to approach objects and situations that are of benefit and to avoid risk. In humans, a large proportion of mental disorders are accompanied by impairments in risk avoidance. One of the most important genes involved in mental disorders is disrupted-in-schizophrenia-1 ( DISC1 ), and animal models in which this gene has some level of dysfunction show emotion-related impairments. However, it is not known whether DISC1 mouse models have an impairment in avoiding potential risks. In the present study, we used DISC1-N terminal truncation ( DISC1-N TM ) mice to investigate risk avoidance and found that these mice were impaired in risk avoidance on the elevated plus maze (EPM) and showed reduced social preference in a three-chamber social interaction test. Following EPM tests, c-Fos expression levels indicated that the nucleus accumbens (NAc) was associated with risk-avoidance behavior in DISC1-N TM mice. In addition, in vivo electrophysiological recordings following tamoxifen administration showed that the firing rates of fast-spiking neurons (FS) in the NAc were significantly lower in DISC1-N TM mice than in wild-type (WT) mice. In addition, in vitro patch clamp recording revealed that the frequency of action potentials stimulated by current injection was lower in parvalbumin (PV) neurons in the NAc of DISC1-N TM mice than in WT controls. The impairment of risk avoidance in DISC1-N TM mice was rescued using optogenetic tools that activated NAc PV neurons. Finally, inhibition of the activity of NAc PV neurons in PV-Cre mice mimicked the risk-avoidance impairment found in DISC1-N TM mice during tests on the elevated zero maze. Taken together, our findings confirm an impairment in risk avoidance in DISC1-N TM mice and suggest that reduced excitability of NAc PV neurons is responsible.

Acupuncture Ameliorates Neuronal Cell Death, Inflammation, and Ferroptosis and Downregulated miR-23a-3p After Intracerebral Hemorrhage in Rats - Ying Kong; Shulin Li; Miao Zhang; Wenting Xu; Qiuxin Chen; Lihong Zheng; Peng Liu; Wei Zou (Journal of Molecular Neuroscience, 2021)

Adaptive Total-Variation Regularized Low-Rank Representation for Analyzing Single-Cell RNA-seq Data - Jin-Xing Liu; Chuan-Yuan Wang; Ying-Lian Gao; Yulin Zhang; Juan Wang; Sheng-Jun Li (Interdisciplinary Sciences: Computational Life Sciences, 2021)

Study on the community structure and function of anaerobic granular sludge under trichloroethylene stress - Qingjuan Meng; Pengfei Li; Jianhua Qu; Ying Liu; Yifan Wang; Zhaobo Chen; Ying Zhang (Ecotoxicology, 2021)

Enhanced β-carotene production by overexpressing the DID2 gene, a subunit of ESCRT complex, in engineered Yarrowia lipolytica - Fan Yang; Liang Liu; Shan Qiang; Ching Yuan Hu; Ying Li; Yong Hong Meng (Biotechnology Letters, 2021)

Mineralogy, fluid inclusions, H-O isotopes, and trace element of the Dongzigou Pb-Zn deposit in the Sangmuchang metallogenic belt, China - Ying Gu; Cuihua Chen; Yulong Yang; Xuhao Kang; Yin Li; Xiaojie Chen; Xiang Lai; Zhijiao Song; Deping Yang; Cheng Jin; Shuyue Liu (Arabian Journal of Geosciences, 2021)

A new benzophenone with biological activities from metabolites of butyrolactone I in rat faeces - Bing Liu; Ning Chen; Ying Xu; Jia-Wei Zhang; Yuan Sun; Li-Zhu Zhao; Yu-bin Ji (Natural Product Research, 2021)

Autophagy blockage promotes the pyroptosis of ox-LDL-treated macrophages by modulating the p62/Nrf2/ARE axis - Jiaru Liu; Chao Wang; Jiashan Li; Ying Yu; Yuee Liu; Huihui Liu; Qi Peng; Xiuru Guan (Journal of Physiology and Biochemistry, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Exposure to antibiotics and mental disorders in children: a community-based cross-sectional study - Jingjing Zhang; Kaiyong Liu; Liang Sun; Linsheng Yang; Xinji Liu; Yitian Zhu; Rong Wei; Zhongxiu Jin; Li Wang; Ying Ma; Sufang Wang; Annuo Liu; et al. (Environmental Geochemistry and Health, 2021)

Sensitive Techniques for POCT Sensing on the Residues of Pesticides and Veterinary Drugs in Food - Lin Liu; Yueying Gao; Jinghan Liu; Ying Li; Ziye Yin; Yuanyuan Zhang; Fuwei Pi; Xiulan Sun (Bulletin of Environmental Contamination and Toxicology, 2021)

Current Progress on Antibiotic Sensing Based on Ratiometric Fluorescent Sensors - Jinghan Liu; Ying Li; Lin Liu; Yueying Gao; Yuanyuan Zhang; Ziye Yin; Fuwei Pi; Xiulan Sun (Bulletin of Environmental Contamination and Toxicology, 2021)

Hydrogeochemical and isotopic characteristics of spring water in the Yarlung Zangbo River Basin, Qinghai-Tibet Plateau, Southwest China - Ying-zhi Li; Zong-jun Gao; Jiu-tan Liu; Min Wang; Cong Han (Journal of Mountain Science, 2021)

Diversity and function of rhizosphere microorganisms between wild and cultivated medicinal plant Glycyrrhiza uralensis Fisch under different soil conditions - Zhou-Yan Dong; Manik Prabhu Narsing Rao; Tian-Jiang Liao; Li Li; Yong-Hong Liu; Min Xiao; Osama Abdalla Abdelshafy Mohamad; Yue-Ying Tian; Wen-Jun Li (Archives of Microbiology, 2021)

Soil lead distribution characteristics and source identification in Hanyuan, upstream of Yangtze River, China - Xiaowen Liu; Dan Zhou; Xue Tang; Ying Li; Ying Yang; Yi Huang (Arabian Journal of Geosciences, 2021)

Clinical features of nine cases of leucine-rich glioma inactivated 1 protein antibody-associated encephalitis - Ying Li; Fan Song; Wei Liu; Ying Wang (Acta Neurologica Belgica, 2021)

Applicability of optimized hyperspectral indices for estimating Betalain content in Suaeda salsa - Rukeya Sawut; Ying Li; Yu Liu; Nijat Kasim; Wei Tao (International Journal of Remote Sensing, 2021)

Risk factors for sleep disorders in patients undergoing peritoneal dialysis - Gui-Ling Liu; Qiu-Nan Zhan; You-Lu Zhao; Zu-Ying Xiong; Jin-Lan Liao; Ye-Ping Ren; Qin Wang; Li-Ping Duan; Zhao-Xia Zheng; Li Hao; Jie Dong (Sleep and Biological Rhythms, 2021)
Sleep disorders in patients with end-stage renal disease are common but have rarely been reported in previous studies. Therefore, we examined the prevalence of sleep disorders and the risk factors for declining sleep quality in patients undergoing peritoneal dialysis (PD). A multicenter prospective cohort study was conducted at five PD centers across different provinces in China. A total of 449 patients who underwent PD between March to November 2013 were enrolled. Demographic data, laboratory indicators, presence of depression, and sleep assessment data were collected. Sleep questionnaires reflecting five categories of sleep disorders, namely, insomnia, restless legs syndrome, excessive daytime sleepiness, possible narcolepsy, and sleepwalking and nightmares, were administered at baseline and at 24 months postoperatively. Sleep disorders were diagnosed when a patient had at least one sleep problem. At baseline, 335 (74.6%) patients had at least one type of sleep disorder. Depression, diabetes mellitus (DM), and male were found to be associated with the presence of a sleep disorder. At follow-up, the prevalence of insomnia, restless legs syndrome, and excessive daytime sleepiness had significantly increased in 285 patients. Furthermore, cardiovascular disease (CVD) was found to be associated with the presence of sleep disorders in patients with one or more disorders at baseline, whereas a low serum albumin level was found to be associated with sleep disorders in patients without any sleep disorders at baseline. The prevalence of sleep disorders was relatively high among PD patients at baseline and increased afterthe2-year follow-up. Depression, DM, and male were associated with all sleep disorders at baseline. CVD was associated with the presence of a sleep disorder at baseline and worse sleep quality at the 2-year follow-up; whereas a low serum albumin level was associated with the risk of acquiring a sleep disorder at the 2-year follow-up among patients with normal sleep status at baseline.

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

PbO2 electrode modified by graphene oxide to boost electrodegradation of 4-hydroxybenzophenone - Ying Fang; Boyu Liu; Xinghao Liu; Qinghui Peng; Haipu Li; Zhaoguang Yang (Environmental Science and Pollution Research, 2021)

Phytochelatins formation kinetics and Cd-induced growth inhibition in Lolium perenne L. at elevated CO2 level under Cd stress - Ying Shi; Yaqi Liu; Houyu Li; Haopeng Pei; Yan Xu; Xuehai Ju (Environmental Science and Pollution Research, 2021)

Cysteiniphilum marinum sp. nov., isolated from coastal seawater - Hai-Min Luo; Jun-Hui Feng; Liang-Hui Li; Meng-Meng Li; Ru-Qin Liu; Fu Chen; Ying Lin; Wen-Jun Li; Ping-Hua Qu; Min Xiao (Antonie van Leeuwenhoek, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Analysis of Sea Ice Timing and Navigability along the Arctic Northeast Passage from 2000 to 2019 - Min Ji; Guochong Liu; Yawen He; Ying Li; Ting Li (Journal of Marine Science and Engineering, 2021)
The ablation of Arctic sea ice makes seasonal navigation possible in the Arctic region, which accounted for the apparent influence of sea ice concentration in the navigation of the Arctic route. This paper uses Arctic sea ice concentration daily data from January 1, 2000, to December 31, 2019. We used a sea ice concentration threshold value of 40% to define the time window for navigating through the Arctic Northeast Passage (NEP). In addition, for the year when the navigation time of the NEP is relatively abnormal, we combined with wind field, temperature, temperature anomaly, sea ice age and sea ice movement data to analyze the sea ice conditions of the NEP and obtain the main factors affecting the navigation of the NEP. The results reveal the following: (1) The sea ice concentration of the NEP varies greatly seasonally. The best month for navigation is September. The opening time of the NEP varies from late July to early September, the end of navigation is concentrated in mid-October, and the navigation time is basically maintained at more than 30 days. (2) The NEP was not navigable in 2000, 2001, 2003 and 2004. The main factors are the high amount of multi-year ice, low temperature and the wind field blowing towards the Vilkitsky Strait and sea ice movement. The navigation time in 2012, 2015 and 2019 was longer, and the driving factors were the high temperature, weak wind and low amount of one-year ice. The navigation time in 2003, 2007 and 2013 was shorter, and the influencing factors were the strong wind field blowing towards the Vilkitsky Strait. (3) The key navigable areas of the NEP are the central part of the East Siberian Sea and the Vilkitsky Strait, and the Vilkitsky Strait has a greater impact on the NEP than the central part of the East Siberian Sea. The main reason for the high concentration of sea ice in the central part of the East Siberian Sea (2000 and 2001) was the large amount of multi-year ice. The main reason for the high concentration of sea ice in the Vilkitsky Strait (2000 to 2004 and 2007, 2013) was the strong offshore wind in summer, all of which were above 4 m s−1, pushing the sea ice near the Vilkitsky Strait to accumulate in the strait, thus affecting the opening of the NEP.

Administration of a recombinant ALDH7A1 (rA7) indicates potential regulation of the metabolite and immunology pathways in Atlantic salmon infected with Aeromonas salmonicida - Xiaohao Li; Kunpeng Fan; Yafang Liu; Ying Liu; Peng‐fei Liu (Journal of Fish Diseases, 2021)
The bacterium Aeromonas salmonicida is the pathogen responsible for furunculosis, which is a serious disease of salmonids. This disease has a significant economic impact on the economic benefits of the global salmon farming industry. However, the pathogenesis of this disease in fish is still unknown. Members of the aldehyde dehydrogenase gene (ALDH) superfamily play a key role in the enzyme detoxification of endogenous and exogenous aldehydes. In this study, we obtained a recombinant aldehyde dehydrogenase 7A1 (ALDH7A1) protein to find its functions on Atlantic salmon infected by A. salmonicida . The transcriptional response in the liver of Atlantic salmon ( Salmo salar ) with differing levels of A. salmonicida infection was analysed and compared in order to reveal mechanisms by which ALDH7A1 may confer infection resistance. With the addition of ALDH7A1 protein, it was found that a total of 13,369 genes were annotated with one or more KEGG and localized to 360 KEGG pathways in the high concentration infection group. The differential expression genes were more enriched in immune signalling pathways such as the Toll‐like receptor signalling pathway, NF‐kappa B signalling pathway and TNF signalling pathway. On the other hand, at low concentrations of infection, KEGG enriched a smaller number of differential expression genes. However, these differential genes were more concentrated in immune signalling pathways such as the PI3K‐Akt signalling pathway, JAK‐STAT signalling pathway and complement and coagulation cascades. In addition, several known immune‐related genes including HSP90α , HSP70 , DNA damage‐inducible transcript 4 , integrin alpha 5 and microtubule‐associated protein 2 were among the differentially expressed transcripts. These data provide the first insights into the host–ALDH7A1 vaccine interactome. The results of this study contribute to identifying the potential resistance mechanisms of Atlantic salmon to A. salmonicida infection and determining future treatment strategies.

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

Mechanism and therapeutic strategies of depression after myocardial infarction - Ying Yang; Xuping Li; Sixuan Chen; Mingzhu Xiao; Zhongqiu Liu; Jingyan Li; Yuanyuan Cheng (Psychopharmacology, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Sublethal dose of warfarin induction promotes the accumulation of warfarin resistance in susceptible Norway rats - Xiaohui Ma; Yan Chen; Yaqi Ying; Yuanzhao Geng; Dawei Wang; Ning Li; Xiao-Hui Liu; Ying Song (Journal of Pest Science, 2021)

Decreased Plasma Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Levels are Linked with Disease Severity in Patients with Liver Cirrhosis - Lian-Ying Yang; Ji-Ping Hou; En-Kun Han; Gang Qiao; Li-Bin Liu; Xue-Bo Men (International Journal of Peptide Research and Therapeutics, 2021)

Performance of VITEK 2, E-test, Kirby–Bauer disk diffusion, and modified Kirby–Bauer disk diffusion compared to reference broth microdilution for testing tigecycline susceptibility of carbapenem-resistant K. pneumoniae and A. baumannii in a multicenter study in China - Dandan Yin; Yan Guo; Min Li; Wenjuan Wu; Jin Tang; Ying Liu; Feng Chen; Yuxing Ni; Jingyong Sun; Hong Zhang; Hu Zhao; Fupin Hu (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

Quantitative human risk analysis of 2015 Shenzhen dump failure considering influence of urbanization - Shuai Zhang; Ying Liu; Bate Bate; Da-lei Peng; Can Li; Liang-tong Zhan (Journal of Mountain Science, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Design of supercontinuum laser hyperspectral light detection and ranging (LiDAR) (SCLaHS LiDAR) - Guoqing Zhou; Xiang Zhou; Youjian Song; Donghui Xie; Long Wang; Guangjian Yan; Minglie Hu; Bowen Liu; Weidong Shang; Chenghu Gong; Cheng Wang; Huaguo Huang; et al. (International Journal of Remote Sensing, 2021)

Recent advances in the application of metabolomics for food safety control and food quality analyses - Shubo Li; Yufeng Tian; Pingyingzi Jiang; Ying Lin; Xiaoling Liu; Hongshun Yang (Critical Reviews in Food Science and Nutrition, 2021)

Integrated LSM-DFN Modeling of Naturally Fractured Reservoirs: Roughness Effect on Elastic Characteristics - Ning Liu; Yang-Ying Li; Li-Yun Fu; Yue Kong; Wu-Shuang Li (Pure and Applied Geophysics, 2021)

Antifungal Effect of Long Noncoding RNA 9708-1 in the Vulvovaginal Candidiasis Murine Model - Ying Wu; Lisha Jiang; Lingling Zhang; Xia Liu; Lina Yan; Ting Luan; Can Rui; Zhiyuan Mao; Chong Fan; Yu Liu; Ping Li; Xin Zeng (Mycopathologia, 2021)
Vulvovaginal candidiasis (VVC) caused by Candida spp. affects 70–75% of women at least once during their lives. We aim to elucidate the potential mechanism of VVC and investigate the therapeutic effects of long noncoding RNA 9708-1. Female BALB/c mice were randomized to four treatment groups, including the blank control group, VVC control group, vehicle control group and lncRNA 9708-1-overexpressed group. Mice were euthanized on Day 4, Day 7 and Day 14 after treatment. Colony-forming unit (CFU) was measured, and the inflammation was detected by hematoxylin and eosin (H&E). Gene and protein expression levels of lncRNA 9708-1 and FAK were determined by real-time PCR, Western blot and immunohistochemistry. The overexpression of lncRNA 9708-1 significantly decreased the fungal load from Day 4 to 7. H&E staining indicated that the impaired histological profiles were improved in lncRNA 9708-1-overexpressed group. LncRNA 9708-1 led to a significant increase in FAK level of vagina tissue which is expressed mainly in epithelial basal layer. This study suggests that lncRNA 9708-1 played a protective role on murine experimental VVC by upregulating the expression levels of FAK.

Development of a pyrF-based counterselectable system for targeted gene deletion in Streptomyces rimosus - Yiying Yang; Qingqing Sun; Yang Liu; Hanzhi Yin; Wenping Yang; Yang Wang; Ying Liu; Yuxian Li; Shen Pang; Wenxi Liu; Qian Zhang; Fang Yuan; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Molecular Characterization of Hsp47 in Grass Carp (Ctenopharyngodon idella) and Its Correlation with Type I Collagen in Response to Fish Aerobic Exercise - Xiao Liang; Ying Wan; Zhiyuan Shen; Yanmei Liu; Dapeng Li; Li Li; Rong Tang; Xi Zhang (Fishes, 2021)
Heat shock protein 47 (Hsp47) is a collagen-specific molecular chaperone that is indispensable for molecular maturation of collagen. In this study, hsp47 and hsp47-like cDNAs were cloned and characterized in grass carp (Ctenopharyngodon idella). The cDNAs were 1212 and 1218 base pairs long, respectively, and included an open reading frame encoding 403 and 405 amino acids. The molecular phylogeny based on the deduced amino acid sequences indicated that the correct sequences of the hsp47 and hsp47-like cDNA were obtained and the deduced proteins clustered distinctly into teleost clades. Primary structure analysis and characterization of Hsp47 and Hsp47-like shared the basic structure and biofunctions of Hsp47 in vertebrates. The spatial pattern of gene expression revealed that hsp47 and hsp47-like were relatively ubiquitous in different tissues and highly expressed in heart and skin. The expression levels of hsp47 and hsp47-like and type I collagen mRNAs varied similarly in different tissues. Type I collagen content increased significantly with the increase of water velocity in the muscle of grass carp in response to aerobic exercise. Among the gene expression changes of hsp47, hsp47-like, col1a1 and col1a2 in muscle that occurred in response to aerobic exercise, the change of type I collagen was most strongly correlated with hsp47 expression. Additionally, col1a1 showed the highest correlation with hsp47-like and col1a2 showed the highest correlation with hsp47. These findings suggest that grass carp Hsp47 and Hsp47-like are closely related to type I collagen synthesis. This study firstly suggests fish aerobic exercise can improve type I collagen content and Hsp47 gene expression in muscle of grass carp.

Effectiveness of Water Management in Producing Cadmium-Safe Rice in Soils of Different Contamination Levels and Physicochemical Properties - Weisheng Lu; Dongqin Li; Ying Liu; Guijie Li; Yang Zhao; Qiuhua Zhang; Zulei Zeng; Huaxing Li; Guikui Chen (Water, Air, & Soil Pollution, 2021)

Subcellular Localization of the D27 Protein in Sugarcane (Saccharum spp. Hybrids) Using an Optimized Protoplast Isolation, Purification, and Transient Gene Expression Protocol - Zhuan-di Wu; Xin Hu; Feng-gang Zan; Yong-bao Pan; David M. Burner; Zheng-ying Luo; Jia-yong Liu; Li-ping Zhao; Li Yao; Yong Zhao; Xin-long Liu; Hong-ming Xia; et al. (Sugar Tech, 2021)

A feedback loop: Interactions between Inflammatory Signals and Clonal Hematopoiesis in Cardiovascular Disease - Jiashan Li; Chao Wang; Jiaru Liu; Ying Yu; Yuee Liu; Qi Peng; Huihui Liu; Xiuru Guan (Molecular Biology Reports, 2021)

A novel homozygous nonsense mutation in the CA2 gene (c.368G>A, p.W123X) linked to carbonic anhydrase II deficiency syndrome in a Chinese family - Yan Yang; Nie Tang; Ying Zhu; Lei Zhang; Xu Cao; Limei Liu; Wei Xia; Pengqiu Li; Yi Yang (Metabolic Brain Disease, 2021)

Associations between SNP83 of phosphodiesterase 4D gene and carotid atherosclerosis in a southern Chinese Han population: a case–control study - Liu-yu Liu; Dong-can Mo; Jian-li Li; Yi-ying Jiang; Guo-qiu Zhou; Dong-dong Jiang; Li-jie Chen; Xiao-ju Wu; Jiao-xing Li; Man Luo (Mammalian Genome, 2021)

A 2-year study on the effects of tillage and straw management on the soil quality and peanut yield in a wheat–peanut rotation system - Jihao Zhao; Zhaoxin Liu; Fang Gao; Ying Wang; Huajiang Lai; Xiaoyi Pan; Dongqing Yang; Xiangdong Li (Journal of Soils and Sediments, 2021)

Dysregulation of circulating follicular helper T cells in type 2 diabetic patients with diabetic retinopathy - Honghua Yu; Baoyi Liu; Guanrong Wu; Zijing Du; Qiaowei Wu; Xiaomin Zeng; Yu Xiao; Ying Fang; Ling Yuan; Suihong Ma; Tao Li (Immunologic Research, 2021)

Calcium signalling mediated the regulation of growth and polysaccharide accumulation by light quality in Dendrobium officinale protocorms - Ting Lei; Suping Gao; Xiao Lin; Kaihui Zhang; Yingqi Liu; Wenji Li; Di Hu; Xiaofang Yu; Mingyan Jiang; Qibing Chen; Ying Sun (Horticulture, Environment, and Biotechnology, 2021)

Characterization of a novel brain cell line from Jian carp (Cyprinus carpio var. Jian) - Ying Li; Yanping Ma; Le Hao; Jiangyao Ma; Zhiling Liang; Zhenxing Liu; Hao Ke; Yugu Li (Fish Physiology and Biochemistry, 2021)

Correction to: Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Bai; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Ba; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Evaluation of genetic diversity and development of core collections of industrial brewing yeast using ISSR markers - Jun Liu; Xiaomin Li; Yueqin Liu; Chengyu Xing; Ying Xie; Guolin Cai; Jian Lu (Archives of Microbiology, 2021)

Gene polymorphism of chalcone isomerase influence the accumulation of flavonoids in licorice (Glycyrrhiza spp.) - Xiaodong Zhang; Shaokai Tian; Lin Qi; Wendong Li; Jiaming Hou; Lin Yang; Zhixin Zhang; Ying Liu (Genetic Resources and Crop Evolution, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Human growth hormone proteoform pattern changes in pituitary adenomas: Potential biomarkers for 3P medical approaches - Biao Li; Xiaowei Wang; Chenguang Yang; Siqi Wen; Jiajia Li; Na Li; Ying Long; Yun Mu; Jianping Liu; Qin Liu; Xuejun Li; Dominic M. Desiderio; et al. (EPMA Journal, 2021)

Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications - Dingyu Wang; Li Sun; Guowei Zhang; Yang Liu; Zhaoguang Liang; Jing Zhao; Shuangli Yin; Mengqi Su; Song Zhang; Ying Wei; He Liu; Desen Liang; et al. (Cardiovascular Toxicology, 2021)

Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease - Meng Zhang; Mengying Wang; Hui Wang; Ying Zhang; Zhengzheng Li; Yiping Feng; Yinan Liu; Yue Liu; Yucheng Liao; Wenjun Wang; Qian Fang; Jinghong Chen (Biological Trace Element Research, 2021)

Arbuscular mycorrhizal colonization rate of an exotic plant, Galinsoga quadriradiata, in mountain ranges changes with altitude - Gang Liu; Rui-Ling Liu; Wen-Gang Zhang; Ying-Bo Yang; Xiao-Qiong Bi; Ming-Zhu Li; Xiao-Yan Chen; Hua Nie; Zhi-Hong Zhu (Mycorrhiza, 2021)

Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China - Qing-Hai Wang; Xiang-Ying Li; Ting-Ting Xu; Meng-Ai Zhang; Yu-Hui Yang; Pei-Bo Feng; Su-Su Fan; Zhen-Yu Liu (Journal of General Plant Pathology, 2021)

Bacillus alkalicellulosilyticus sp. nov., isolated from extremely alkaline bauxite residue (red mud) site - Guo-Hong Liu; Manik Prabhu Narsing Rao; Xiao-Ying Wang; Tong-Wei Chu; Bo Liu; Wen-Jun Li (Archives of Microbiology, 2021)

Antioxidant and anti-inflammatory constituents from Flos populi - Yong Hou; Guangjie Zhang; Min Li; Bowen Li; Li Chen; Ying Tian; Shijun Liu; Bin Li; Junxing Dong (Natural Product Research, 2021)

Application of soil phytoliths to the quantitative characterization of temperate grassland ecosystems: a case study in Northeast China - Guizai Gao; Dehui Li; Dongmei Jie; Nannan Li; Lidan Liu; Hongyan Liu; Jiangyong Wang; Honghao Niu; Meng Meng; Ying Liu; Guihua Zhang (Plant and Soil, 2021)

Transcriptome Analysis Identifies SenZfp536, a Sense LncRNA that Suppresses Self-renewal of Cortical Neural Progenitors - Kuan Tian; Andi Wang; Junbao Wang; Wei Li; Wenchen Shen; Yamu Li; Zhiyuan Luo; Ying Liu; Yan Zhou (Neuroscience Bulletin, 2021)

High Heterogeneity of Root Carbon Allocation Affects Root Turnover Rate and Production of Bothriochloa ischaemum Under Drought Stress - Ying Liu; Peng Li; Lie Xiao; Kuxia Yu; Wen Wang (Journal of Plant Growth Regulation, 2021)

The Association Between Trace Elements Exposure and the Cognition in the Elderly in China - Ling Gu; Jinhui Yu; Yong Fan; Sufang Wang; Linsheng Yang; Kaiyong Liu; Qunan Wang; Guimei Chen; Dongmei Zhang; Ying Ma; Li Wang; Annuo Liu; et al. (Biological Trace Element Research, 2021)

Evaluating the efficiency of wind protection by windbreaks based on remote sensing and geographic information systems - Xiguang Yang; Fengri Li; Wenyi Fan; Guiwei Liu; Ying Yu (Agroforestry Systems, 2021)

Extraordinary diversity of viruses in deep‐sea sediments as revealed by metagenomics without prior virion separation - Xiaowei Zheng; Wang Liu; Xin Dai; Yaxin Zhu; Jinfeng Wang; Yongqiang Zhu; Huajun Zheng; Ying Huang; Zhiyang Dong; Wenbin Du; Fangqing Zhao; Li Huang (Environmental Microbiology, 2021)
Summary Our current knowledge of the virosphere in deep‐sea sediments remains rudimentary. Here we investigated viral diversity at both gene and genomic levels in deep‐sea sediments of Southwest Indian Ocean. Analysis of 19 676 106 non‐redundant genes from the metagenomic DNA sequences revealed a large number of unclassified viral groups in these samples. A total of 1106 high‐confidence viral contigs were obtained after two runs of assemblies, and 217 of these contigs with sizes up to ~120 kb were shown to represent complete viral genomes. These contigs are clustered with no known viral genomes, and over 2/3 of the ORFs on the viral contigs encode no known functions. Furthermore, most of the complete viral contigs show limited similarity to known viral genomes in genome organization. Most of the classified viral contigs are derived from dsDNA viruses belonging to the order Caudovirales , including primarily members of the families Myoviridae , Podoviridae and Siphoviridae . Most of these viruses infect Proteobacteria and, less frequently, Planctomycetes , Firmicutes , Chloroflexi , etc. Auxiliary metabolic genes (AMGs), present in abundance on the viral contigs, appear to function in modulating the host ability to sense environmental gradients and community changes, and to uptake and metabolize nutrients.

PapA , a peptidoglycan‐associated protein, interacts with OmpC and maintains cell envelope integrity - Yun‐Hao Wang; Hong‐He Chen; Zhou Huang; Xiao‐Jing Li; Nan Zhou; Chang Liu; Cheng‐Ying Jiang; De‐Feng Li; Shuang‐Jiang Liu (Environmental Microbiology, 2021)
Summary The bacterial cell envelope is critical to support and maintain cellular life. In Gram‐negative bacterial cells, the outer membrane and the peptidoglycan layer are two important parts of the cell envelope and they harbour abundant proteins. Here, we report the identification and characterization of a previously unknown p eptidoglycan‐ a ssociated p rotein, PapA, from the Gram‐negative Comamonas testosteroni . PapA bound peptidoglycan with its C‐terminal domain and interacted with the outer‐membrane porin OmpC. The PapA‐OmpC complex riveted the outer membrane and the peptidoglycan layer, and played a role in maintaining cell envelope integrity. When papA was disrupted, the mutant CNB‐1Δ papA apparently had an outer membrane partly separated from the peptidoglycan layer. Phenotypically, the mutant CNB‐1Δ papA lost chemotactic responses and had longer lag‐phase of growth, less flagellation and higher sensitivity to harsh environments. Totally, 1093 functionally unknown PapA homologues were identified from the public NR protein database and they were mainly distributed in Burkholderiales of Betaproteobacteria. Our finding provides a clue that the PapA homologous proteins might function as a rivet to maintain cell envelope integrity in those Gram‐negative bacteria.

Velocity Measurement of Coherent Doppler Sonar Assisted by Frequency Shift, Kalman Filter and Linear Prediction - Peng Liu; Nobuyoshi Kouguchi; Ying Li (Journal of Marine Science and Engineering, 2021)
Velocity is vital information for navigation and oceanic engineering. Coherent Doppler sonar is an accurate tool for velocity measurement, but its use is limited due to velocity ambiguity. Velocity measured by frequency shift has no velocity ambiguity, yet its measurement error is larger than that of coherent Doppler sonar. Therefore, coherent Doppler sonar assisted by frequency shift is used to accurately measure velocity without velocity ambiguity. However, the velocity measured by coherent Doppler sonar assisted by frequency shift is affected by impulsive noise. To decrease the impulsive noise, Kalman filter and linear prediction are proposed to improve the velocity sensing accuracy. In this method, the Kalman filter is used to decrease measurement error of velocity measured by frequency shift, and linear prediction is used to remove the impulsive noise generated by a wrong estimate of the integer ambiguity. Lab-based experiments were carried, and the results have shown that coherent Doppler sonar assisted by frequency shift, Kalman filter and linear prediction can provide accurate and precise velocity with short time delay in a large range of signal to noise ratio.

Satellite Remote Sensing for Estimating PM2.5 and Its Components - Ying Li; Shuyun Yuan; Shidong Fan; Yushan Song; Zihao Wang; Zujun Yu; Qinghua Yu; Yiwen Liu (Current Pollution Reports, 2021)

Development and application of a comparative risk assessment method for ranking chemical hazards in food - Ying Li; Guoxin Liang; Lei Zhang; Zhaoping Liu; Dajin Yang; Jianwen Li; Guiju Sun; Pingping Zhou (Food Additives & Contaminants: Part A, 2021)

Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human - Ya-Xin Fan; Yuan-Cheng Chen; Yi Li; Ji-Cheng Yu; Xing-Chen Bian; Xin Li; Wan-Zhen Li; Bei-Ning Guo; Hai-Lan Wu; Xiao-Fen Liu; Yu Wang; Xiao-Yong Xu; et al. (Pharmaceutical Research, 2021)

7,8-Dihydroxyflavone Alleviates Anxiety-Like Behavior Induced by Chronic Alcohol Exposure in Mice Involving Tropomyosin-Related Kinase B in the Amygdala - Na Wang; Xing Liu; Xin-Tong Li; Xin-Xin Li; Wei Ma; Yan-Min Xu; Yong Liu; Qing Gao; Tao Yang; Hongxuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2021)

Study on NOx removal from simulated flue gas by an electrobiofilm reactor: EDTA-ferrous regeneration and biological kinetics mechanism - Nan Liu; Ying-ying Li; Du-juan Ouyang; Rui Guo; Run Chen; Wei Li; Ji-xiang Li; Ji-hong Zhao (Environmental Science and Pollution Research, 2021)

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Stability Assessment of Intracranial Aneurysms Using Machine Learning Based on Clinical and Morphological Features - Wei Zhu; Wenqiang Li; Zhongbin Tian; Yisen Zhang; Kun Wang; Ying Zhang; Jian Liu; Xinjian Yang (Translational Stroke Research, 2020)

Transcriptomic analysis reveals somatic embryogenesis-associated signaling pathways and gene expression regulation in maize (Zea mays L.) - Meiqi Ding; Haixiao Dong; Yingjie Xue; Shengzhong Su; Ying Wu; Shipeng Li; Hongkui Liu; He Li; Junyou Han; Xiaohui Shan; Yaping Yuan (Plant Molecular Biology, 2020)

N2O Emissions Mitigation in Acidic Soil Following Biochar Application Under Different Moisture Regimes - Muhammad Aamer; Muhammad Shaaban; Muhammad Umair Hassan; Liu Ying; Tang Haiying; Ma Qiaoying; Hassan Munir; Adnan Rasheed; Li Xinmei; Li Ping; Huang Guoqin (Journal of Soil Science and Plant Nutrition, 2020)

Effects of Short-Term Application of Chemical and Organic Fertilizers on Bacterial Diversity of Cornfield Soil in a Karst Area - Ying Li; Xiuming Liu; Lin Zhang; Yuanhuan Xie; Xianli Cai; Shijie Wang; Bin Lian (Journal of Soil Science and Plant Nutrition, 2020)

High-throughput sequencing reveals the molecular mechanisms determining the stay-green characteristic in soybeans - Cheng Wang; Le Gao; Run Zhi Li; Ye Wang; Yang Ying Liu; Xin Zhang; Hao Xie (Journal of Biosciences, 2020)

Transcriptome-wide identification and profiling of miRNAs in a stress-tolerant conifer Sabina chinensis - Xian-Ge Hu; Shan-Shan Zhou; Ying Yang; Hui Liu; Shrestha Anil; Qing Wang; Wei Zhao; Qiong Gao; Yousry A El-Kassaby; Tongli Wang; Yue Li; Jian-Feng Mao (Journal of Biosciences, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Comparison Between the Gut Microbiota in Different Gastrointestinal Segments of Large-Tailed Han and Small-Tailed Han Sheep Breeds with High-Throughput Sequencing - Guangli Yang; Shuhong Zhang; Zhiqiang Li; Jie Huang; Yan Liu; Ying Liu; Qiankun Wang; Xiangyu Li; Yongfeng Yan; Ming Li (Indian Journal of Microbiology, 2020)

Effects of MC-LR on histological structure and cell apoptosis in the kidney of grass carp (Ctenopharyngodon idella) - Li He; Lin Liu; Changgao Lin; Jiming Ruan; Ximei Liang; Ying Zhou; Lili Wei (Fish Physiology and Biochemistry, 2020)

Ecological risk assessment of heavy metals in fish from the Dianchi Lake, China using the integrated biomarker response approach - Ying Gao; Li Fang; Qian Qian Xiang; Di Wang; Liu Yong Ding; Cheng Zhi Ding; Li Qiang Chen (Environmental Science and Pollution Research, 2020)

Correction to: The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans - Jin-Yan Liu; Bing Wei; Ying Wang; Ce Shi; Wen-Jing Li; Yue Zhao; Ling-Ning Meng; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2020)

The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans - Jin-Yan Liu; Bing Wei; Ying Wang; Ce Shi; Wen-Jing Li; Yue Zhao; Ling-Ning Meng; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2020)

Dynamic network connectivity predicts subjective cognitive decline: the Sino-Longitudinal Cognitive impairment and dementia study - Guozhao Dong; Liu Yang; Chiang-shan R. Li; Xiaoni Wang; Yihe Zhang; Wenying Du; Ying Han; Xiaoying Tang (Brain Imaging and Behavior, 2020)

Cortical 3-hinges could serve as hubs in cortico-cortical connective network - Tuo Zhang; Xiao Li; Xi Jiang; Fangfei Ge; Shu Zhang; Lin Zhao; Huan Liu; Ying Huang; Xianqiao Wang; Jian Yang; Lei Guo; Xiaoping Hu; et al. (Brain Imaging and Behavior, 2020)
Mapping the relation between cortical convolution and structural/functional brain architectures could provide deep insights into the mechanisms of brain development, evolution and diseases. In our previous studies, we found a unique gyral folding pattern, termed a 3-hinge, which was defined as the conjunction of three gyral crests. The uniqueness of the 3-hinge was evidenced by its thicker cortex and stronger fiber connections than other gyral regions. However, the role that 3-hinges play in cortico-cortical connective architecture remains unclear. To this end, we conducted MRI studies by constructing structural cortico-cortical connective networks based on a fine-granular cortical parcellation, the parcels of which were automatically labeled as 3-hinge, 2-hinge (ordinary gyrus) or sulcus. On human brains, 3-hinges possess significantly higher degrees, strengths and betweennesses than 2-hinges, suggesting that 3-hinges could serve more like hubs in the cortico-cortical connective network. This hypothesis gains supports from human functional network analyses, in which 3-hinges are involved in more global functional networks than ordinary gyri. In addition, 3-hinges could serve as ‘connector’ hubs rather than ‘provincial’ hubs and they account for a dominant proportion of nodes in the high-level ‘backbone’ of the network. These structural results are reproduced on chimpanzee and macaque brains, while the roles of 3-hinges as hubs become more pronounced in higher order primates. Our new findings could provide a new window to the relation between cortical convolution, anatomical connection and brain function.

Frequency-dependent changes in fractional amplitude of low-frequency oscillations in Alzheimer’s disease: a resting-state fMRI study - Liu Yang; Yan Yan; Yuxia Li; Xiaochen Hu; Jie Lu; Piu Chan; Tianyi Yan; Ying Han (Brain Imaging and Behavior, 2020)

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

Time-reverse location of microseismic sources in viscoelastic orthotropic anisotropic medium based on attenuation compensation - Tang Jie; Liu Ying-Chang; Wen Lei; Li Cong (Applied Geophysics, 2020)

Prediction and Identification of Epitopes in the Emy162 Antigen of Echinococcus multilocularis - Ming-Quan Pang; Feng Tang; Hai-Jiu Wang; Ying Zhou; Li Ren; Run-Le Li; Hu Zhou; Chen-Fei Wan; Chuan-Chuan Liu; Cai-Rang Yangdan; Hai-Ning Fan (Acta Parasitologica, 2020)

The ROK ‐family regulator Rok7B7 directly controls carbon catabolite repression, antibiotic biosynthesis, and morphological development in Streptomyces avermitilis - Xiaorui Lu; Xingchao Liu; Zhi Chen; Jilun Li; Gilles P. van Wezel; Wei Chen; Ying Wen (Environmental Microbiology, 2020)
Summary Carbon catabolite repression (CCR) is a common phenomenon in bacteria that modulates expression of genes involved in uptake of alternative carbon sources. In the filamentous streptomycetes, which produce half of all known antibiotics, the precise mechanism of CCR is yet unknown. We report here that the ROK‐family regulator Rok7B7 pleiotropically controls xylose and glucose uptake, CCR, development, as well as production of the macrolide antibiotics avermectin and oligomycin A in Streptomyces avermitilis . Rok7B7 directly repressed structural genes for avermectin biosynthesis, whereas it activated olmRI , the cluster‐situated activator gene for oligomycin A biosynthesis. Rok7B7 also directly repressed the xylose uptake operon xylFGH , whose expression was induced by xylose and repressed by glucose. Both xylose and glucose served as Rok7B7 ligands. rok7B7 deletion led to enhancement and reduction of avermectin and oligomycin A production, respectively, relieved CCR of xylFGH , and increased co‐uptake efficiency of xylose and glucose. A consensus Rok7B7‐binding site, 5′‐TTKAMKHSTTSAV‐3′, was identified within aveA1p , olmRIp , and xylFp , which allowed prediction of the Rok7B7 regulon and confirmation of 11 additional targets involved in development, secondary metabolism, glucose uptake, and primary metabolic processes. Our findings will facilitate methods for strain improvement, antibiotic overproduction, and co‐uptake of xylose and glucose in Streptomyces species.

Cascade marker removal algorithm for thyroid ultrasound images - Xiang Ying; Yulin Zhang; Mei Yu; Xi Wei; Jialin Zhu; Jie Gao; Zhiqiang Liu; Hongqian Shen; Ruixuan Zhang; Xuewei Li; Ruiguo Yu (Medical & Biological Engineering & Computing, 2020)

Removal of antipyrine through two-dimensional and three-dimensional electrolysis: comparison, modification, and improvement - Pengxiao Liu; Xu Wang; Jing Lu; Ying Li; Bin Hou; Ling Feng (Environmental Science and Pollution Research, 2020)

Forest age mapping based on multiple-resource remote sensing data - Xiguang Yang; Yuqi Liu; Zechuan Wu; Ying Yu; Fengri Li; Wenyi Fan (Environmental Monitoring and Assessment, 2020)

The coupling mechanism between the suitable space and rural settlements considering the effect of mountain hazards in the upper Minjiang River basin - Ying Liu; Wei Deng; Li Peng (Journal of Mountain Science, 2020)

Development and current state of seawater shrimp farming, with an emphasis on integrated multi‐trophic pond aquaculture farms, in China – a review - Zhi‐Qiang Chang; Amir Neori; Yu‐Ying He; Ji‐Tao Li; Ling Qiao; Steven Ian Preston; Ping Liu; Jian Li (Reviews in Aquaculture, 2020)
Shrimp farming has been the fastest‐growing sector in seawater aquaculture and has contributed to improving the farmers income and the utilization efficiency of aquaculture resources in China. The shrimp industry has deployed ever‐improved and innovated methods, from extensive farming to semi‐intensive and intensive farming. Various high‐density intensive culture models, such as high‐land, greenhouse and indoor industrialized culture models, have been used for shrimp pond farming in the coastal area. However, efficiency, environmental and social considerations have led to an increasing adoption of the environmentally‐friendly culture model called integrated multi‐trophic aquaculture (IMTA). This has occurred most rapidly along the northern and central coasts of China. The deployed IMTA culture models reviewed here are shrimp + crab, shrimp + fish, shrimp + sea cucumber, shrimp + jellyfish + clam, shrimp + crab + clam, shrimp + crab + clam + fish and the ridgetail white shrimp polyculture in saline alkaline water, which have been tailored to local conditions and organisms' characteristics. Suitable organism varieties and the maintenance of suitable eco‐friendly water quality have been key to success. The eco‐friendly IMTA culture models described here fully exploit the pond culture resources, to increase production with minimal additional feed and labor inputs, while reducing effluent emissions and treatment cost. The performance of shrimp IMTA models is compared to shrimp monoculture models regarding the economics. An equally important outcome of this publication is making generally accessible the findings from a vast Chinese scientific literature on shrimp culture that has hitherto been unavailable in English.

A new accuracy evaluation method for water body extraction - Hui Yue; Yao Li; Jiaxin Qian; Ying Liu (International Journal of Remote Sensing, 2020)

Adsorption Mechanism and Structure-Performance Relationship of Chromium Ions by Biochar - Menghong Li; Xiaoli Guo; Ying Wei; Aiju Liu; Jie Lu; Xiaoyin Niu; Yanfei Ma; Shuang Li; Zhenxiao Shang; Xinpeng Liu (Water, Air, & Soil Pollution, 2020)

Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis - Ning Xiao; Tian-long Liu; Hao Li; Hao-chen Xu; Jing Ge; Hong-yan Wen; Cong-xia Bai; Li Song; Ying-ying Sun; Yin-hui Zhang; Ru-tai Hui; Wei-hua Song; et al. (Translational Stroke Research, 2020)

New Value-Added Sugar and Brown Sugar Products from Sugarcane: A Commercial Approach - Liu Yang; Shi-Yan Shen; Zhi-Neng Wang; Ting Yang; Jia-Wen Guo; Rui-Yun Hu; Yan-Fang Li; David M. Burner; Xiong-Mei Ying (Sugar Tech, 2020)

Upregulation of long non-coding RNA MEG3 in type 2 diabetes mellitus complicated with vascular disease: a case–control study - Wei-wei Chang; Liu Zhang; Xin-ming Yao; Yan Chen; Li-jun Zhu; Zheng-mei Fang; Ying Zhao; Ying-shui Yao; Yue-long Jin (Molecular and Cellular Biochemistry, 2020)

Integrated biomarker parameters response to the toxic effects of high stocking density, CuSO4, and trichlorfon on fish and protective role mediated by Angelica sinensis extract - HuaTao Li; YuTing Ma; Ying Liu; Min Wu; Jiao Long; XiaoQin Jing; SiShun Zhou; Ping Yuan; Jun Jiang (Fish Physiology and Biochemistry, 2020)

Seasonal Rainfall Forecasts for the Yangtze River Basin of China in Summer 2019 from an Improved Climate Service - Philip E. Bett; Nicola Martin; Adam A. Scaife; Nick Dunstone; Gill M. Martin; Nicola Golding; Joanne Camp; Peiqun Zhang; Chris D. Hewitt; Leon Hermanson; Chaofan Li; Hong-Li Ren; et al. (Journal of Meteorological Research, 2020)

Spatiotemporal Characteristics of Rural Labor Migration in China: Evidence from the Migration Stability under New-type Urbanization - Wei Deng; Shaoyao Zhang; Peng Zhou; Li Peng; Ying Liu; Jiangjun Wan (Chinese Geographical Science, 2020)

The mRNA expression of ompF, invA and invE was associated with the ciprofloxacin-resistance in Salmonella - Xiongwei Du; Ying Liu; Xiaojie Sun; Jianmei Zhao; Juan Wang; Jianping Li; Xuelian Liu; Junwei Wang; Ye Li (Archives of Microbiology, 2020)

A high-quality genome sequence of alkaligrass provides insights into halophyte stress tolerance - Wenting Zhang; Jie Liu; Yongxue Zhang; Jie Qiu; Ying Li; Baojiang Zheng; Fenhong Hu; Shaojun Dai; Xuehui Huang (Science China Life Sciences, 2020)

Associations of egg consumption with incident cardiovascular disease and all-cause mortality - Xue Xia; Fangchao Liu; Xueli Yang; Jianxin Li; Jichun Chen; Xiaoqing Liu; Jie Cao; Chong Shen; Ling Yu; Yingxin Zhao; Xianping Wu; Liancheng Zhao; et al. (Science China Life Sciences, 2020)

Correction to: LncRNA NONRATT021972 involved the pathophysiologic processes mediated by P2X7 receptors in stellate ganglia after myocardial ischemic injury - Lifang Zou; Guihua Tu; Wei Xie; Shiyao Wen; Qiuyu Xie; Shuangmei Liu; Guilin Li; Yun Gao; Hong Xu; Shouyu Wang; Yun Xue; Bing Wu; et al. (Purinergic Signalling, 2020)

A novel compound heterozygous mutation of SLC12A3 gene in a pedigree with Gitelman syndrome and literature review - Minglan Yang; Ying Dong; Jianqing Tian; Li Yan; Yawen Chen; Huiying Qiu; Wei Liu; Yaomin Hu (Genes & Genomics, 2020)

First case of Shewanella indica isolated from a Bryde’s whale (Balaenoptera edeni) stranded in the northern Beibu Gulf, China - Jia Li; Richard W. McLaughlin; Mo Chen; Ying Li Liu; Hia Xia Xie; Xiao Ling Wan; Jun Ying Zhou; Jin Song Zheng (Antonie van Leeuwenhoek, 2020)

Study on Mercury Methylation in Phragmites australis Soil and Its Influencing Factors - Zhang Shiwei; Zheng Dongmei; Xin Yuan; Mao Ying; Shi Liu; Li Huiying (Water, Air, & Soil Pollution, 2020)

A fundamental theorem for eco-environmental surface modelling and its applications - Tianxiang Yue; Na Zhao; Yu Liu; Yifu Wang; Bin Zhang; Zhengping Du; Zemeng Fan; Wenjiao Shi; Chuanfa Chen; Mingwei Zhao; Dunjiang Song; Shihai Wang; et al. (Science China Earth Sciences, 2020)

A novel plant protein-disulfide isomerase participates in resistance response against the TYLCV in tomato - Tong Li; Ya-Hui Wang; Ying Huang; Jie-Xia Liu; Guo-Ming Xing; Sheng Sun; Sen Li; Zhi-Sheng Xu; Ai-Sheng Xiong (Planta, 2020)

Morphological and physiological variations of Cyclocarya paliurus under different soil water capacities - Ying Feng; Xiulian Lin; Lianwen Qian; Nengjing Hu; Chunfeng Kuang; Xiaofeng Li; Zheng Li; Liangrui Huang; Mingming Liu (Physiology and Molecular Biology of Plants, 2020)

Impaired Parahippocampal Gyrus–Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease - Lin Zhu; Zan Wang; Zhanhong Du; Xinyang Qi; Hao Shu; Duan Liu; Fan Su; Qing Ye; Xuemei Liu; Zheng Zhou; Yongqiang Tang; Ru Song; et al. (Neuroscience Bulletin, 2020)

The Probability and Sensitivity Analysis of Slope Stability Under Seepage Based on Reliability Theory - Tao Li; Guodong Liu; Cong Wang; Xuwang Wang; Ying Li (Geotechnical and Geological Engineering, 2020)

Trichloroethylene inhibits nitrogen transformation and microbial community structure in Mollisol - Pengfei Li; Ying Zhang; Qingjuan Meng; Ying Liu; Diogene Tuyiringire; Zhaobo Chen; Shichao Liang (Ecotoxicology, 2020)

Pseudomonas Saliphila sp. nov., a Bacterium Isolated from Oil-Well Production Water in Qinghai Oilfield of China - Xiao-Juan Zhang; Hong-Can Liu; Yu-Guang Zhou; Xiao-Lei Wu; Yong Nie; Qi-Rui Li; Mei-Zhu Wang; Liang Zhao; Man Cai; Ying-Qian Kang (Current Microbiology, 2020)

Naphthalene exerts non-target effects on the abundance of active fungi by stimulating basidiomycete abundance - Li-ying Lan; Li Zhang; Ya Shen; Jian Zhang; Wan-qin Yang; Zhen-feng Xu; Yang Liu; Shu-qin He; Wei Zhou; Han Li; Li-xia Wang; Si-ning Liu; et al. (Journal of Mountain Science, 2020)

Taxonomy and Phylogeny of a New Marine Planktonic Ciliate, Strombidium pseudorapulum sp. n. (Protozoa, Ciliophora, Oligotrichia) - Fenfen Li; Yaoyao Huang; Ying Yu; Weiwei Liu; Xiaofeng Lin (Journal of Ocean University of China, 2020)

Different experiences of two PRRT2-associated self-limited familial infantile epilepsy - Qianlei Zhao; Zhenwei Liu; Ying Hu; Shiyu Fang; Feixia Zheng; Xiucui Li; Feng Li; Zhongdong Lin (Acta Neurologica Belgica, 2020)
To analyze the clinical characteristics and PRRT2 gene mutation of self-limited familial infantile epilepsy and evaluate the treatment responses of different antiepileptic drugs in self-limited familial infantile epilepsy. We reviewed the clinical feature and genetic mutation results and treatment responses of two sibling sisters. They were detected with the PRRT2 gene mutation through Sanger sequencing. Elder sister was treated with oxcarbazepine oral suspension, while younger sister was treated with levetiracetam oral solution. The two sibling sisters exhibited PRRT2 heterozygous mutation inherited from their mother in c.649dupC p.(Arg217fs). Oxcarbazepine oral suspension had an immediate effect on the elder sister who was treated with it. However, levetiracetam oral solution had no effect on younger sister even though the dose was increased, but she got seizure-free after turning to oxcarbazepine oral suspension. Oxcarbazepine, which plays the mechanism of the sodium channel blockers, has a more significant effect than levetiracetam, which has no mechanism of the sodium channel blockers in self-limited familial infantile epilepsy. The PRRT2 gene of infantile epileptic patients with a family history of infantile convulsions or paroxysmal kinesigenic dyskinesia(PKD) could be detected by sanger sequencing and a biomarker to select antiepileptic drugs which play the mechanism of the sodium channel blockers could be utilized.

Impacts of climate anomalies on the interannual and interdecadal variability of autumn and winter haze in North China: A review - Jing Wang; Yanju Liu; Yihui Ding; Ping Wu; Zhiwei Zhu; Ying Xu; Qiaoping Li; Yingxian Zhang; Jinhai He; Julian X. L. Wang; Li Qi (International Journal of Climatology, 2020)
From the perspectives of remote sensing and climatic factors like surface meteorological parameters, large‐scale atmospheric circulations, and external forcing factors (EFFs), the authors synthesize and review spatiotemporal variations of PM 2.5 over North China and how climate anomalies affect autumn and winter haze variability in North China according to recent studies. This review focuses on both interannual and interdecadal timescales. It is shown that circulations play an important role in influencing haze variability. Atmospheric circulations, which would be modulated by EFFs like sea surface temperature, sea ice, and snowpack, can affect the climate variability in haze over North China via modulation of surface‐layer parameters that are closely connected with the haze phenomenon. Therefore, EFFs are deemed significant factors impacting the climate variability of haze over North China, serving as paramount precursory signals for haze prediction. Furthermore, this paper suggests potential future research directions for haze variability studies in North China on the basis of summarizing and concluding the associated processes/mechanisms on how climatic factors affect haze variability, which could provide reference for treating and forecasting in situ hazy conditions.

Design and synthesis of novel 7-[( N -substituted-thioureidopiperazinyl)-methyl]-camptothecin derivatives as potential cytotoxic agents - Zi-Long Song; Guan-Zhou Yang; Jun-Cai Li; Ying-Qian Liu; Chen-Jie Yang; Masuo Goto; Zhi-Jun Zhang; Susan L. Morris-Natschke; Hua Liu; Kuo-Hsiung Lee (Natural Product Research, 2020)

Characterization of viromes within mosquito species in China - Jiang Du; Fan Li; Yelin Han; Shihong Fu; Bo Liu; Nan Shao; Haoxiang Su; Weijia Zhang; Dandan Zheng; Wenwen Lei; Jie Dong; Lilian Sun; et al. (Science China Life Sciences, 2020)

Heterogeneity in short-term allocation of carbon to roots of Pinus tabuliformis seedlings and root respiration under drought stress - Ying Liu; Peng Li; Lie Xiao; Wen Wang; Kunxia Yu; Peng Shi (Plant and Soil, 2020)

Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort - Wei-Wei Li; Zhen Wang; Dong-Yu Fan; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Ling Li; Heng Yang; Yu-Hui Liu; Xian-Le Bu; Wang-Sheng Jin; Fan Zeng; et al. (Neuroscience Bulletin, 2020)

Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family - Juan Zhang; Yanjun Liu; Ming Li; Xiaoxu Ge; Ying Wang; Xin Huang; Di Yang; Rong Zhang; Yating Chen; Ming Lu; Jun Yin; Mingqiang Song; et al. (Molecular and Cellular Biochemistry, 2020)

CYP2B6 Polymorphisms Are Associated with Ischemic Stroke Risk in a Chinese Han Population - Guolong Tu; Wenliang Zhan; Yao Sun; Jiamin Wu; Zichao Xiong; Jianfeng Liu; Yuanwei Liu; Haiyue Li; Ying Xia (Journal of Molecular Neuroscience, 2020)

A novel nonlinear hyperspectral unmixing approach for images of oil spills at sea - Ying Li; Huimin Lu; Zhenduo Zhang; Peng Liu (International Journal of Remote Sensing, 2020)

Development of a specific AFLP-based SCAR marker for Chinese Race 34MKG of Puccinia graminis f. sp. tritici - Si Chen; Xue Yang; Wen-gong Huang; Yan Liu; Ying Yu; Guang-wen Wu; Shu-quan Zhang; Tian-ya Li; Yuan-yin Cao (Molecular Biology Reports, 2020)

Long-Term Greenhouse Cucumber Production Alters Soil Bacterial Community Structure - Xing Liu; Yujiao Li; Xiujuan Ren; Bihua Chen; Ying Zhang; Changwei Shen; Fei Wang; Dafu Wu (Journal of Soil Science and Plant Nutrition, 2020)

Enhanced tenogenic differentiation and tendon-like tissue formation by Scleraxis overexpression in human amniotic mesenchymal stem cells - Xizhong Zhu; Ziming Liu; Shuhong Wu; Yuwan Li; Huazhang Xiong; Gang Zou; Ying Jin; Jibin Yang; Qi You; Jun Zhang; Yi Liu (Journal of Molecular Histology, 2020)

Inhibition of glycolysis ameliorate arthritis in adjuvant arthritis rats by inhibiting synoviocyte activation through AMPK/NF-кB pathway - Ying Wang; Hao Xian; Jiajia Qi; Fang Wei; Xiu Cheng; Sha Li; Qing Wang; Zhaoyang Liu; Yun Yu; Jing Zhou; Xiaojin Sun; Hao Liu; et al. (Inflammation Research, 2020)

Screening of single-cell clonal lines from Papilio demoleus Linnaeus cell lines for exogenous protein expression and adaptation in serum-free culture - Wei-Feng Ding; Zhi-Gang Liu; Na Sun; Xin Zhang; Xian Li; Ying Feng (In Vitro Cellular & Developmental Biology - Animal, 2020)

Chronic Copper Exposure Induces Hypospermatogenesis in Mice by Increasing Apoptosis Without Affecting Testosterone Secretion - Hanming Chen; Zhenlong Kang; Na Qiao; Gaoyang Liu; Kebin Huang; Xi Wang; Congying Pang; Qiwen Zeng; Zhaoxin Tang; Ying Li (Biological Trace Element Research, 2020)

Modulation of the Intraseasonal Variability of Pacific-Japan Pattern by ENSO - Ying Li; Fei Liu; Pang-Chi Hsu (Journal of Meteorological Research, 2020)

Science and Prediction of Heavy Rainfall over China: Research Progress since the Reform and Opening-Up of New China - Yali Luo; Jisong Sun; Ying Li; Rudi Xia; Yu Du; Shuai Yang; Yuanchun Zhang; Jing Chen; Kan Dai; Xueshun Shen; Haoming Chen; Feifan Zhou; et al. (Journal of Meteorological Research, 2020)

Endophytic colonization by Beauveria bassiana increases the resistance of tomatoes against Bemisia tabaci - Qiu-Yang Wei; Ya-Ying Li; Chen Xu; Yi-Xia Wu; Ya-Ru Zhang; Huai Liu (Arthropod-Plant Interactions, 2020)
Beauveria bassiana , an entomopathogenic fungus, can exist asymptomatically as an endophyte in many plants. This study aimed to determine the efficiency of B. bassiana colonization of tomato plants using different inoculation methods, and how colonization of the host plant affects the key pest of tomato, the whitefly Bemisia tabaci . To confirm fungal colonization efficiency, nested PCR technique was used to detect B. bassiana sequences in Solanum lycopersicum . Distribution of the fungus within the plant parts was determined by selective medium. Tomato growth parameters were determined with plants that had been inoculated using direct spraying or irrigation of the rhizosphere. B. tabaci performance assays were carried out in a cage, and preference to treatments was determined using Y-tube olfactometer studies. Results show that B. bassiana can effectively colonize tomato, with colonization rate using leaf spraying reaching 100% within 14 days. Fungal presence was not uniformly distributed among plant parts, but was biased towards the inoculation sites. For inoculation, conidial suspension sprayed at 1 × 10 8 conidia/ml resulted in the highest number of isolated colonies in leaf tissue, 8.5 ± 2.02 colonies per 2 g of fresh tissue ( F 4,19 = 2.779, P = 0.045), and reached the lowest with root treatment. Although only small differences were observed among the growth indicators, leaf spray inoculation resulted in a significant positive influence on plant growth (PC1 55.7% contributions scores = 2.645) in further Principal component analysis. As for the feeding selectivity, B. tabaci preferred uninoculated plants. In Y-tube olfactometer assay, 80.5% of adults selected uninoculated plants. These findings add to the understanding of the interactions between B. bassiana and plants and indicate the potential of expanding the use of entomopathogenic fungi for crop protection.

Baicalein attenuates caspase-independent cells death via inhibiting PARP-1 activation and AIF nuclear translocation in cerebral ischemia/reperfusion rats - Wei-Han Li; Ying-Lin Yang; Xiao Cheng; Man Liu; Shan-Shan Zhang; Yue-Hua Wang; Guan-Hua Du (Apoptosis, 2020)

In-situ nitrogen fate in the vadose zone of different soil types and its implications for groundwater quality in the Huaihe River Basin, China - Rongfu Li; Xiaohong Ruan; Tianhai Ma; Ying Bai; Congqiang Liu (Acta Geochimica, 2020)

Proteomic Comparison of the Cytotoxicology of Two Diastereomers of Citreamicin Reveals Differentially Activation of NF-κB Pathway - Ling-Li Liu; Jin Sun; Ying Xu; Li-Sheng He; Chandramouli Kondethimmanahalli; Pei-Yuan Qian (Frontiers in Marine Science, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

Physiological and proteomic responses of mangrove plant Avicennia marina seedlings to simulated periodical inundation - Huan Li; Zan Li; Zhi-Jun Shen; Mei-Rong Luo; Yi-Ling Liu; Ming-Yue Wei; Wen-Hua Wang; Ying-Ying Qin; Chang-Hao Gao; Ke-Ke Li; Qian-Su Ding; Shan Zhang; et al. (Plant and Soil, 2020)

Colletotrichum fructicola STE50 is required for vegetative growth, asexual reproduction, appressorium formation, pathogenicity and the response to external stress - Yan-ying Chen; Jun-ang Liu; Shi-qiang Jiang; He Li; Guo-ying Zhou (Journal of Plant Pathology, 2020)

Dynamic Alterations of Brain Injury, Functional Recovery, and Metabolites Profile after Cerebral Ischemia/Reperfusion in Rats Contributes to Potential Biomarkers - Xiao Cheng; Ying-Lin Yang; Wei-Han Li; Man Liu; Shan-Shan Zhang; Yue-Hua Wang; Guan-Hua Du (Journal of Molecular Neuroscience, 2020)

Evaluating the effects of transgenic Bt rice cultivation on soil stability - Ying-ying Song; Jia-wen Liu; Li-kun Li; Man-qiang Liu; Xiao-yun Chen; Fa-jun Chen (Environmental Science and Pollution Research, 2020)

Integrated fate assessment of aromatic amines in aerobic sewage treatment plants - Lin Jun Zhou; Zhi Yi Rong; Wen Gu; De Ling Fan; Ji Ning Liu; Li Li Shi; Yan Hua Xu; Zhi Ying Liu (Environmental Monitoring and Assessment, 2020)
The fate and exposure of chemicals in sewage treatment plants (STPs) are major considerations in risk assessment and environmental regulation. The biodegradability and removal of seven aromatic amines were systematically evaluated using a three-tiered integrated method: a standard ready biodegradability test, an aerobic sewage treatment simulation method, and model prediction. In tier 1, the seven aromatic amines were not readily biodegraded after 28 days. In adapted aerobic active sludge, 4-isopropyl aniline, 2,4-diaminotoluene, and 4-nitroaniline among them exhibited the degradation half-life time less than 20 h, the other four aromatic amines exhibited persistent with degradation half-life of > 60 h. In tier 2 of the aerobic sewage treatment simulation testing, 2,4-diaminotoluene, 4-nitroaniline, and 4-isopropylaniline demonstrated moderately to high overall removal. Hydraulic retention time (HRT) affects the removal with the optimum HRT was determined to be 12 h to 24. 2,6-Dimethyl aniline, 2-chloro-4-nitroaniline, 2,6-diethylaniline, and 3,4-dichloroaniline were not removed during the test, indicting these four aromatic amines will enter surface water and hence pose a potential risk to aquatic ecology. Considering the lack of an STP model in China for regulation purposes, in tier 3, we developed a Chinese STP (aerobic) (abbreviated as C-STP(O)) model that reflects a universal scenario for China to predict the fate. The predicted degradation, volatilization, and absorption showed a close relationship to the physicochemical properties of the chemicals, and had same tendency with tier 2 simulation test. The prediction showed that biodegradation rather than absorption or volatilization was the main removal process of aromatic amines in aerobic STP. With the combination of modified kinetics test with C-STP (O) model, the chemical fate can be more accurately predicted than using only the readily biodegradation result.

The nucleic acid positive rate and genotype distribution of human cytomegalovirus in human milk banks in China - Xiaoyu Min; Lin Wang; Aili Cui; Chunli Zhang; Dan Wang; Ying Liu; Zhenghong Li; Wenbo Xu (Archives of Virology, 2020)

SP94 Peptide-Functionalized PEG-PLGA Nanoparticle Loading with Cryptotanshinone for Targeting Therapy of Hepatocellular Carcinoma - Xiaoling Nie; Yuan Liu; Ming Li; Xuesong Yu; Wanwen Yuan; Sixi Huang; Di Ren; Ying Wang; Yan Wang (AAPS PharmSciTech, 2020)

A new triterpenoid saponin from Pulsatilla cernua predicted by NMR-based mosaic method - An-Dong Wang; Ying Bao; Xia Wang; Mei-Chen Li; Xu-Hong Ren; Jian-Yu Liu; Yong-Nan Xu (Natural Product Research, 2020)

Perfusion Changes of Unexplained Early Neurological Deterioration After Reperfusion Therapy - Jingjing Fu; Ying Zhou; Qingqing Li; Genlong Zhong; Sheng Zhang; Ruiting Zhang; Chang Liu; Minming Zhang; Min Lou (Translational Stroke Research, 2020)

Contribution of Baroreflex Afferent Pathway to NPY-Mediated Regulation of Blood Pressure in Rats - Yang Liu; Shu-Yang Zhao; Yan Feng; Jie Sun; Xiao-Long Lu; Qiu-Xin Yan; Ying Li; Zhuo Liu; Lu-Qi Wang; Xun Sun; Shijun Li; Guo-Fen Qiao; et al. (Neuroscience Bulletin, 2020)

Retraction Note to: Effects of dietary glycerol monolaurate on productive performance, egg quality, serum biochemical indices, and intestinal morphology of laying hens - Min-jie Zhao; Hai-ying Cai; Meng-yun Liu; Ling-li Deng; Yang Li; Hui Zhang; Feng-qin Feng (Journal of Zhejiang University-SCIENCE B, 2020)

Correction to: Limb Remote Ischemic Preconditioning Reduces Repeated Ketamine Exposure-Induced Adverse Effects in the Developing Brain of Rats - Ying Liu; An Qi Li; Wan Ma; Yu Bo Gao; Li Qin Deng; Chun Zhang; Jin Hai Meng (Journal of Molecular Neuroscience, 2020)

Combined effects of elevated temperature and pCO2 on the production of DMSP and DMS in the culture of Amphidinium carterae - Pei-Feng Li; Gui-Peng Yang; Chun-Ying Liu (Journal of Applied Phycology, 2020)

Correction to: The Effects of 50 nm Unmodified Nano-ZnO on Lipid Metabolism and Semen Quality in Male Mice - Tao Kong; Shu-Hui Zhang; Cai Zhang; Ji-Liang Zhang; Fan Yang; Guo-Yong Wang; Zi-Jun Yang; Dong-Ying Bai; Yun-Yun Shi; Tian-Qi Liu; Hai-Long Li (Biological Trace Element Research, 2020)

The Effects of 50 nm Unmodified Nano-ZnO on Lipid Metabolism and Semen Quality in Male Mice - Tao Kong; Shu-Hui Zhang; Cai Zhang; Ji-Liang Zhang; Fan Yang; Guo-Yong Wang; Zi-Jun Yang; Dong-Ying Bai; Yun-Yun Shi; Tian-Qi Liu; Hai-Long Li (Biological Trace Element Research, 2020)

Geochemistry, Sr-Nd-Pb Isotopic Compositions and Zircon U-Pb Geochronology of Neoproterozoic Mafic Dyke in the Douling Complex, South Qinling Belt, China - Tong Li; Liang Liu; Xiao-Ying Liao; Yong-Sheng Gai; Tuo Ma; Chao Wang (Journal of Earth Science, 2020)

Polymorphisms in arsenic (+ 3 oxidation state) methyltransferase (AS3MT) predict the occurrence of hyperleukocytosis and arsenic metabolism in APL patients treated with As2O3 - Wen-Sheng Liu; Xin-Yu Wang; Jing Lu; Ying-Mei Zhang; Xiang-Mei Ye; Jin-Mei Li; Qi-Lei Zhao; Zhi-Qiang Wu; Jin Zhou; Xin Hai (Archives of Toxicology, 2020)

Poly(L-Glutamic Acid)-Based Brush Copolymers: Fabrication, Self-assembly, and Evaluation as Efficient Nanocarriers for Cationic Protein Drug Delivery - Xin Li; Chao Lu; Wenquan Xia; Guilan Quan; Ying Huang; Xuequn Bai; Feiyuan Yu; Qian Xu; Wanbing Qin; Daojun Liu; Xin Pan (AAPS PharmSciTech, 2020)

Variation and evolution of C:N ratio among different organs enable plants to adapt to N‐limited environments - Jiahui Zhang; Nianpeng He; Congcong Liu; Li Xu; Zhi Chen; Ying Li; Ruomeng Wang; Guirui Yu; Wei Sun; Chunwang Xiao; Han Y. H. Chen; Peter B. Reich (Global Change Biology, 2020)
Carbon (C) and nitrogen (N) are the primary elements involved in the growth and development of plants. The C:N ratio is an indicator of nitrogen use efficiency (NUE) and an input parameter for some ecological and ecosystem models. However, knowledge remains limited about the convergent or divergent variation in the C:N ratios among different plant organs (e.g., leaf, branch, trunk, and root) and how evolution and environment affect the coefficient shifts. Using systematic measurements of the leaf–branch–trunk–root of 2,139 species from tropical to cold‐temperate forests, we comprehensively evaluated variation in C:N ratio in different organs in different taxa and forest types. The ratios showed convergence in the direction of change but divergence in the rate of change. Plants evolved toward lower C:N ratios in the leaf and branch, with N playing a more important role than C. The C:N ratio of plant organs (except for the leaf) was constrained by phylogeny, but not strongly. Both the change of C:N during evolution and its spatial variation (lower C:N ratio at midlatitudes) help develop the adaptive growth hypothesis. That is, plants with a higher C:N ratio promote NUE under strong N‐limited conditions to ensure survival priority, whereas plants with a lower C:N ratio under less N‐limited environments benefit growth priority. In nature, larger proportion of species with a high C:N ratio enabled communities to inhabit more N‐limited conditions. Our results provide new insights on the evolution and drivers of C:N ratio among different plant organs, as well as provide a quantitative basis to optimize land surface process models.

Contrasting the Pb (II) and Cd (II) tolerance of Enterobacter sp. via its cellular stress responses - Zhongquan Jiang; Liu Jiang; Lin Zhang; Mu Su; Da Tian; Tong Wang; Yalin Sun; Ying Nong; Shuijin Hu; Shimei Wang; Zhen Li (Environmental Microbiology, 2020)
Summary Successful application of microorganisms to heavy metal remediation depends on their resistance to toxic metals. This study contrasted the differences of tolerant mechanisms between Pb 2+ and Cd 2+ in Enterobacter sp. Microbial respiration and production of formic acid showed that Enterobacter sp. had a higher tolerant concentration of Pb (>1000 mg l −1 ) than Cd (about 200 mg l −1 ). Additionally, SEM confirmed that most of Pb and Cd nanoparticles (NPs) were adsorbed onto cell membrane. The Cd stress, even at low concentration (50 mg l −1 ), significantly enlarged the sizes of cells. The cellular size raised from 0.4 × 1.0 to 0.9 × 1.6 μm on average, inducing a platelet‐like shape. In contrast, Pb cations did not stimulate such enlargement even up to 1000 mg l −1 . Moreover, Cd NPs were adsorbed homogeneously by almost all the bacterial cells under TEM. However, only a few cells work as ‘hot spots’ on the sorption of Pb NPs. The heterogeneous sorption might result from a ‘self‐sacrifice’ mechanism, i.e., some cells at a special life stage contributed mostly to Pb sorption. This mechanism, together with the lower mobility of Pb cations, caused higher microbial tolerance and removal efficiency towards Pb 2+ . This study sheds evident contrasts of bacterial resistance to the two most common heavy metals.

Identification and characterization of a novel gene-encoded antioxidant peptide obtained from amphibian skin secretions - Ying Wang; Xiaoqing Cao; Zhe Fu; Siyuan Wang; Xiaojie Li; Naixin Liu; Zhuo Feng; Meifeng Yang; Jing Tang; Xinwang Yang (Natural Product Research, 2020)

Chemical constituents, cytotoxic and antioxidant activities of extract from the rhizomes of Osmunda japonica Thunb - Li Bowen; Chen Li; Li Bin; Tian Ying; Liu Shijun; Dong Junxing (Natural Product Research, 2020)

An Improved Digital Volumetric Speckle Photography Technique with X-ray Microtomography and its Applications to Investigating Strain Localization in Red Sandstone - Lingtao Mao; Ying Zhu; Yuwei Wang; Yifan Liu; Liyun Li; Fu-pen Chiang (Rock Mechanics and Rock Engineering, 2020)

Bioaugmentation-assisted phytoremediation of manganese and cadmium co-contaminated soil by Polygonaceae plants (Polygonum hydropiper L. and Polygonum lapathifolium L.) and Enterobacter sp. FM-1 - Yi Li; Jiamin Lin; Yuanyuan Huang; Yawei Yao; Xueru Wang; Chengzhao Liu; Ying Liang; Kehui Liu; Fangming Yu (Plant and Soil, 2020)

Primary age-related tauopathy in a Chinese cohort - Xin Wang; Lei Zhang; Hui Lu; Juan-li Wu; Hua-zheng Liang; Chong Liu; Qing-qing Tao; Zhi-ying Wu; Ke-qing Zhu (Journal of Zhejiang University-SCIENCE B, 2020)

Effects of freeze-thaw cycles and initial soil moisture content on soil aggregate stability in natural grassland and Chinese pine forest on the Loess Plateau of China - Lie Xiao; Kehan Yao; Peng Li; Ying Liu; Yi Zhang (Journal of Soils and Sediments, 2020)

Genetic structure and demographic histories of two sympatric Culter species in eastern China - Ying Xiong; Wei Li; Jing Yuan; Tanglin Zhang; Zhongjie Li; Wuhan Xiao; Jiashou Liu (Journal of Oceanology and Limnology, 2020)

Antioxidant Peptide AOP-P1 Derived from Odorous Frog Showed Protective Effects Against UVB-Induced Skin Damages - Saige Yin; Shanshan Li; Wenxin Bian; Meifeng Yang; Naixin Liu; Yan Hu; Xiaojie Li; Ying Wang; Ziliang Li; Jun Sun; Xinwang Yang (International Journal of Peptide Research and Therapeutics, 2020)

Impacts of climate change, population growth, and urbanization on future population exposure to long-term temperature change during the warm season in China - Wei Zhang; Ying Li; Zhuang Li; Xin Wei; Ting Ren; Jie Liu; Yan Zhu (Environmental Science and Pollution Research, 2020)

Association of Blood Lead Levels with the Risk of Depressive Symptoms in the Elderly Chinese Population: Baseline Data of a Cohort Study - Yong Fan; Jie Sheng; Chunmei Liang; Linsheng Yang; Kaiyong Liu; Qunan Wang; Dongmei Zhang; Ying Ma; Xiude Li; Shaoyu Xie; Hongjuan Cao; Sufang Wang; et al. (Biological Trace Element Research, 2020)

Detection of Small Ship Objects Using Anchor Boxes Cluster and Feature Pyramid Network Model for SAR Imagery - Peng Chen; Ying Li; Hui Zhou; Bingxin Liu; Peng Liu (Journal of Marine Science and Engineering, 2020)
The synthetic aperture radar (SAR) has a special ability to detect objects in any climate and weather conditions. Consequently, SAR images are widely used in maritime transportation safety and fishery law enforcement for maritime object detection. Currently, deep-learning models are being extensively used for the detection of objects from images. Among them, the feature pyramid network (FPN) uses pyramids for representing semantic information regardless of the scale and has an improved accuracy of object detection. It is also suitable for the detection of multiple small ship objects in SAR images. This study aims to resolve the problems associated with small-object and multi-object ship detection in complex scenarios e.g., when a ship nears the port, by proposing a detection method based on an optimized FPN model. The feature pyramid model is first embedded in a traditional region proposal network (RPN) and mapped into a new feature space for object identification. Subsequently, the k-means clustering algorithm based on the shape similar distance (SSD) measure is used to optimize the FPN. Initial anchor boxes and tests are created using the SAR ship dataset. Experimental results show that the proposed algorithm for object detection shows an accuracy of 98.62%. Compared with Yolo, the RPN based on VGG/ResNet, FPN based on VGG/ResNet, and other models in complex scenarios, the proposed model shows a higher accuracy rate and better overall performance.

Relative roles of formation and preservation on gold endowment along the Sanshandao gold belt in the Jiaodong gold province, China: importance for province- to district-scale gold exploration - Liang Zhang; David I. Groves; Li-Qiang Yang; Gong-Wen Wang; Xiang-Dong Liu; Da-Peng Li; Ying-Xin Song; Wei Shan; Si-Chen Sun; Zhao-Kun Wang (Mineralium Deposita, 2020)