Development of a pyrF-based counterselectable system for targeted gene deletion in Streptomyces rimosus - Yiying Yang; Qingqing Sun; Yang Liu; Hanzhi Yin; Wenping Yang; Yang Wang; Ying Liu; Yuxian Li; Shen Pang; Wenxi Liu; Qian Zhang; Fang Yuan; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Selenium Supplementation Protects Against Lipopolysaccharide-Induced Heart Injury via Sting Pathway in Mice - Xuan Wang; Bin Yang; Hui-Li Cao; Rui-Ying Wang; Zhao-Yang Lu; Rui-Fang Chi; Bao Li (Biological Trace Element Research, 2021)

Genome analysis of Salmonella phage vB_SalM_8-19 (genus Rosemountvirus) - Cong Cong; Wei Bing Dong; Cui Hui Jing; Yuan Yu Yu; Xu Yong Ping; Wang Li Li; Li Shu Ying; Li Ji Bin; Xu Mu; Li Xiao Yu (Archives of Microbiology, 2021)

Two novel flavonoids from the leaves of Rhododendron dauricum L. with their inhibition of TNF-α production in LPS-induced RAW 264.7 cells - Chao Ye; Mei Jin; Chunshi Jin; Rongshen Wang; Jiaming Wang; Ying Zhang; Sainan Li; Jinfeng Sun; Wei Zhou; Gao Li (Natural Product Research, 2021)

Comparison of Metabolic Profiling of Arabidopsis Inflorescences Between Landsberg erecta and Columbia, and Meiosis-Defective Mutants by 1H-NMR Spectroscopy - Xiang Li; Hongkuan Wang; Ying Wang; Limin Zhang; Yingxiang Wang (Phenomics, 2021)

A feedback loop: Interactions between Inflammatory Signals and Clonal Hematopoiesis in Cardiovascular Disease - Jiashan Li; Chao Wang; Jiaru Liu; Ying Yu; Yuee Liu; Qi Peng; Huihui Liu; Xiuru Guan (Molecular Biology Reports, 2021)

A 2-year study on the effects of tillage and straw management on the soil quality and peanut yield in a wheat–peanut rotation system - Jihao Zhao; Zhaoxin Liu; Fang Gao; Ying Wang; Huajiang Lai; Xiaoyi Pan; Dongqing Yang; Xiangdong Li (Journal of Soils and Sediments, 2021)

Editorial Expression of Concern: The bio-mitigation of acetochlor in soil using Rhodopseudomonas capsulata in effluent after wastewater treatment - Pan Wu; Bo Cao; Ying Zhang; Wenbin Li; Yanling Wang; Yuan Wu; Ning Li (Journal of Soils and Sediments, 2021)

Uremic toxin indoxyl sulfate promotes proinflammatory macrophage activation by regulation of β-catenin and YAP pathways - Ying Li; Jing Yan; Minjia Wang; Jing Lv; Fei Yan; Jin Chen (Journal of Molecular Histology, 2021)
Evidence has been shown that indoxyl sulfate (IS) could impair kidney and cardiac functions. Moreover, macrophage polarization played important roles in chronic kidney disease and cardiovascular disease. IS acts as a nephron-vascular toxin, whereas its effect on macrophage polarization during inflammation is still not fully elucidated. In this study, we aimed to investigate the effect of IS on macrophage polarization during lipopolysaccharide (LPS) challenge. THP-1 monocytes were incubated with phorbol 12-myristate-13-acetate (PMA) to differentiate into macrophages, and then incubated with LPS and IS for 24 h. ELISA was used to detect the levels of TNFα, IL-6, IL-1β in THP-1-derived macrophages. Western blot assay was used to detect the levels of arginase1 and iNOS in THP-1-derived macrophages. Percentages of HLA-DR-positive cells (M1 macrophages) and CD206-positive cells (M2 macrophages) were detected by flow cytometry. IS markedly increased the production of the pro-inflammatory factors TNFα, IL-6, IL-1β in LPS-stimulated THP-1-derived macrophages. In addition, IS induced M1 macrophage polarization in response to LPS, as evidenced by the increased expression of iNOS and the increased proportion of HLA-DR+ macrophages. Moreover, IS downregulated the level of β-catenin, and upregulated the level of YAP in LPS-stimulated macrophages. Activating β-catenin signaling or inhibiting YAP signaling suppressed the IS-induced inflammatory response in LPS-stimulated macrophages by inhibiting M1 polarization. IS induced M1 macrophage polarization in LPS-stimulated macrophages via inhibiting β-catenin and activating YAP signaling. In addition, this study provided evidences that activation of β-catenin or inhibition of YAP could alleviate IS-induced inflammatory response in LPS-stimulated macrophages. This finding may contribute to the understanding of immune dysfunction observed in chronic kidney disease and cardiovascular disease.

Forecasting of COVID-19 onset cases: a data-driven analysis in the early stage of delay - Xueli Wang; Ying Li; Jinzhu Jia (Environmental Science and Pollution Research, 2021)

Photosynthetic and physiological responses to acetochlor in paired near-isogenic lines of waxy maize (Zea mays L.) - Ying Feng; Xuemei Zhong; Yuhan Yao; Zhensheng Shi; Fenghai Li; Hongwei Wang; Xiangling Lv; Wanli Du; Min Zhu; Hu Yang; Dexuan Meng (Environmental Science and Pollution Research, 2021)

Correction to: Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Bai; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Ba; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Correction to: A Preliminary Toxicology Study on Eco-friendly Control Target of Spodoptera frugiperda - Li-Kui Wang; Fen Li; Wayne Jiang; Wen-Bo Duan; Ehab Abdelraheem; Zheng-Qiang Peng; Farag Malhat; Shao-Ying Wu (Bulletin of Environmental Contamination and Toxicology, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

Multifactor-controlled mid-infrared spectral and emission characteristic of carbonate minerals (MCO3, M = Mg, Ca, Mn, Fe) - Ying Zhu; Yanzhang Li; Hongrui Ding; Anhuai Lu; Yan Li; Changqiu Wang (Physics and Chemistry of Minerals, 2021)

Stable isotopes and chloride ion of precipitation events in the northeastern Tibetan Plateau, China - Bu-li Cui; Dong-sheng Li; Bao-fu Jiang; Ying Wang; Ya-xuan Wang; Long-sheng Wang; Xiao-yan Li (Journal of Mountain Science, 2021)

Detection of Geochemical Element Assemblage Anomalies Using a Local Correlation Approach - Xianchuan Yu; Shicheng Wang; Hao Wang; Yuchen Liang; Siying Chen; Kang Wu; Zhaoying Yang; Chongyang Li; Yunzhen Chang; Ying Zhan; Wang Yao; Dan Hu (Journal of Earth Science, 2021)

A preliminary study of the weathering mechanism of fossilized Cretaceous Hamipterus bones - Ying Li; Wugan Luo; Yimin Yang; Shunxing Jiang; Xiaolin Wang (Science China Earth Sciences, 2021)

Litter addition and understory removal influenced soil organic carbon quality and mineral nitrogen supply in a subtropical plantation forest - Xiang-Min Fang; G. Geoff Wang; Zhi-Jun Xu; Ying-Ying Zong; Xiu-Lan Zhang; Jian-Jun Li; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

Groundwater sources, flow patterns, and hydrochemistry of the Central Yinchuan Plain, China - Ying Li; Ping Wu; Xiao-Qin Huang; Bo Zhang; Zhao-Xiang Xu; Yang Li; Jie Li; Lu-Chen Wang; Yu-Fang Sun; Xu-Chen Meng; Cheng-Wen Wang; Zi-Zhao Cai (Hydrogeology Journal, 2021)

Comprehensive upstream and downstream regulatory analyses identify miR-675-3p as a potential prognostic biomarker in melanoma - Cai-Chou Zhao; Hao Guo; Ying Wang; Jiu-Hong Li (Human Cell, 2021)
This study assessed miR-675-3p-related regulatory mechanisms in melanoma and the clinical relevance of such regulatory activities. We downloaded miRNA mature strand expression RNA-Seq, phenotypic, and DNA methylation data pertaining to the TCGA Melanoma cohort. Differentially expressed miRNAs (DEMs) between metastatic and primary melanoma patient tissues were then identified, and miR-675-3p expression in melanoma patient peripheral blood was confirmed using the GSE20994 GEO dataset, while its expression in melanoma cell lines was evaluated via qRT-RCR. The clinical and prognostic implications of miR-675-3p in melanoma were assessed, and miR-675-3p target genes were identified using bioinformatics tools. Functional roles of this miRNA were explored via Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. We identified 3 and 22 miRNAs that were up- and downregulated, respectively, in metastatic melanoma samples relative to primary melanoma samples. Upregulation of miR-675-3p was associated with poorer overall patient survival, tumor histologic grade, and Clark's level. Consistently, miR-675-3p was also overexpressed in the peripheral blood of melanoma patients relative to healthy controls, and in melanoma cell lines relative to control cells. Gene regulatory networks indicated that 32 transcription factors control miR-675-3p expression, and that it, in turn, regulates 10 target genes. KEGG analyses indicated that these genes were associated with cell cycle, transcriptional misregulation in cancer, TGF-beta signaling, and HIF-1 signaling pathways. Gain-of-function assays revealed that miR-675-3p could promote cell proliferation via accelerating cell cycle progression. Western blotting results indicated that miR-675-3p could active TGF-beta and HIF-1 signaling. Through upstream and downstream analyses of miR-675-3p-related regulatory activity, we confirmed that this miRNA participates in key melanoma-related processes and offers value as a prognostic biomarker in melanoma patients.

Human growth hormone proteoform pattern changes in pituitary adenomas: Potential biomarkers for 3P medical approaches - Biao Li; Xiaowei Wang; Chenguang Yang; Siqi Wen; Jiajia Li; Na Li; Ying Long; Yun Mu; Jianping Liu; Qin Liu; Xuejun Li; Dominic M. Desiderio; et al. (EPMA Journal, 2021)

Genetic diversity analysis of Topmouth Culter (Culter alburnus) based on microsatellites and D-loop sequences - Ning Sun; Dong-Mei Zhu; Qing Li; Gui-Ying Wang; Jian Chen; Feifei Zheng; Pei Li; Yan-Hong Sun (Environmental Biology of Fishes, 2021)

Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications - Dingyu Wang; Li Sun; Guowei Zhang; Yang Liu; Zhaoguang Liang; Jing Zhao; Shuangli Yin; Mengqi Su; Song Zhang; Ying Wei; He Liu; Desen Liang; et al. (Cardiovascular Toxicology, 2021)

Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease - Meng Zhang; Mengying Wang; Hui Wang; Ying Zhang; Zhengzheng Li; Yiping Feng; Yinan Liu; Yue Liu; Yucheng Liao; Wenjun Wang; Qian Fang; Jinghong Chen (Biological Trace Element Research, 2021)

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China - Qing-Hai Wang; Xiang-Ying Li; Ting-Ting Xu; Meng-Ai Zhang; Yu-Hui Yang; Pei-Bo Feng; Su-Su Fan; Zhen-Yu Liu (Journal of General Plant Pathology, 2021)

Identification of genetic variants in m6A modification genes associated with pancreatic cancer risk in the Chinese population - Pingting Ying; Yao Li; Nan Yang; Xiaoyang Wang; Haoxue Wang; Heng He; Bin Li; Xiating Peng; Danyi Zou; Ying Zhu; Rong Zhong; Xiaoping Miao; et al. (Archives of Toxicology, 2021)

Bacillus alkalicellulosilyticus sp. nov., isolated from extremely alkaline bauxite residue (red mud) site - Guo-Hong Liu; Manik Prabhu Narsing Rao; Xiao-Ying Wang; Tong-Wei Chu; Bo Liu; Wen-Jun Li (Archives of Microbiology, 2021)

Improved seismoacoustic analysis model and its application to source parameter inversion of near-surface small-yield chemical explosions - Zhang Liang-Yong; Li Xin; Liang Xu-Bin; Wang Tong-Dong; Tang Shi-Ying; Zhang De-Zhi; Zeng Xin-Wu (Applied Geophysics, 2021)

Prestack seismic stochastic inversion based on statistical characteristic parameters - Wang Bao-Li; Lin Ying; Zhang Guang-Zhi; Yin Xing-Yao; Zhao Chen (Applied Geophysics, 2021)

Measuring solar irradiance profiles in the Arctic sea ice using fiber optic spectrometry via inclined holes - Zexia Qiu; Hangzhou Wang; Tao Li; Hong Song; Yuanqian Wu; Tingting Yan; Ying Chen (Acta Oceanologica Sinica, 2021)

Network pharmacology uncovers anti-cancer activity of vibsane-type diterpenes from Viburnum odoratissimum - Ying-Ying Zhang; Jing-Jie Chen; Dan-Qi Li; Yan- Zhang; Xiao-Bo Wang; Guo-Dong Yao; Shao-Jiang Song (Natural Product Research, 2021)

Transcriptional and post-transcriptional regulation of the miR171-LaSCL6 module during somatic embryogenesis in Larix kaempferi - Qiao-Lu Zang; Yao Zhang; Su-Ying Han; Wan-Feng Li; Li-Wang Qi (Trees, 2021)
Key message Expression analysis of Larix kaempferi mature miR171s and their primary transcripts and target gene LaSCL6 during somatic embryogenesis revealed the transcriptional and post-transcriptional regulation of the miR171- LaSCL6 module. Abstract Somatic embryogenesis provides a useful experimental system for studying the regulatory mechanisms of plant development. The level and activity of microRNA171 (miR171) fluctuate during somatic embryogenesis in Larix kaempferi , but the underlying mechanisms are still unclear. Here, in L. kaempferi we identified five members of the miR171 family, which cleave LaSCL6 mRNA at different sites. In addition, we improved the method of measuring miRNA activity in a more direct way. Furthermore, we measured the expression patterns of mature miR171s and their primary transcripts during somatic embryogenesis in L. kaempferi and found that their patterns differed, indicating that the transcription of MIR171 genes and the subsequent cleavage of their intermediate products are regulated. Taken together, our findings not only offer a means to study the regulation of miRNA activity, but also provide further insight into the regulation of L . kaempferi somatic embryogenesis by miR171- LaSCL6 .

Carnosic acid alleviates depression-like behaviors on chronic mild stressed mice via PPAR-γ-dependent regulation of ADPN/FGF9 pathway - Xiao-qing Wang; Ya-hui Tang; Gui-rong Zeng; Li-feng Wu; Ying-jun Zhou; Ze-neng Cheng; De-Jian Jiang (Psychopharmacology, 2021)

Application of soil phytoliths to the quantitative characterization of temperate grassland ecosystems: a case study in Northeast China - Guizai Gao; Dehui Li; Dongmei Jie; Nannan Li; Lidan Liu; Hongyan Liu; Jiangyong Wang; Honghao Niu; Meng Meng; Ying Liu; Guihua Zhang (Plant and Soil, 2021)

Transcriptome Analysis Identifies SenZfp536, a Sense LncRNA that Suppresses Self-renewal of Cortical Neural Progenitors - Kuan Tian; Andi Wang; Junbao Wang; Wei Li; Wenchen Shen; Yamu Li; Zhiyuan Luo; Ying Liu; Yan Zhou (Neuroscience Bulletin, 2021)

High Heterogeneity of Root Carbon Allocation Affects Root Turnover Rate and Production of Bothriochloa ischaemum Under Drought Stress - Ying Liu; Peng Li; Lie Xiao; Kuxia Yu; Wen Wang (Journal of Plant Growth Regulation, 2021)

Effects of sulfur limitation on nitrogen and sulfur uptake and lipid accumulation in Scenedesmus acuminatus - Qianya Wang; Ying Zhang; Huijuan Wu; Ning Xu; Aifen Li (Journal of Applied Phycology, 2021)

Compound heterozygous mutation of the ASXL3 gene causes autosomal recessive congenital heart disease - Fang Fu; Ru Li; Ting-ying Lei; Dan Wang; Xin Yang; Jin Han; Min Pan; Li Zhen; Jian Li; Fa-tao Li; Xiang-yi Jing; Dong-zhi Li; et al. (Human Genetics, 2021)

A Preliminary Toxicology Study on Eco-friendly Control Target of Spodoptera frugiperda - Li-Kui Wang; Fen Li; Wayne Jiang; Wen-Bo Duan; Ehab Abdelraheem; Zheng-Qiang Peng; Farag Malhat; Shao-Ying Wu (Bulletin of Environmental Contamination and Toxicology, 2021)

The Association Between Trace Elements Exposure and the Cognition in the Elderly in China - Ling Gu; Jinhui Yu; Yong Fan; Sufang Wang; Linsheng Yang; Kaiyong Liu; Qunan Wang; Guimei Chen; Dongmei Zhang; Ying Ma; Li Wang; Annuo Liu; et al. (Biological Trace Element Research, 2021)

Control effects of the synsedimentary faults on the basin-marginal fans in the central part of the deep-water area of early Oligocene Qiongdongnan Basin, South China Sea - Guangzeng Song; Zengxue Li; Haizhang Yang; Dongdong Wang; Ying Chen; Rui Sun (Acta Oceanologica Sinica, 2021)

Extraordinary diversity of viruses in deep‐sea sediments as revealed by metagenomics without prior virion separation - Xiaowei Zheng; Wang Liu; Xin Dai; Yaxin Zhu; Jinfeng Wang; Yongqiang Zhu; Huajun Zheng; Ying Huang; Zhiyang Dong; Wenbin Du; Fangqing Zhao; Li Huang (Environmental Microbiology, 2021)
Summary Our current knowledge of the virosphere in deep‐sea sediments remains rudimentary. Here we investigated viral diversity at both gene and genomic levels in deep‐sea sediments of Southwest Indian Ocean. Analysis of 19 676 106 non‐redundant genes from the metagenomic DNA sequences revealed a large number of unclassified viral groups in these samples. A total of 1106 high‐confidence viral contigs were obtained after two runs of assemblies, and 217 of these contigs with sizes up to ~120 kb were shown to represent complete viral genomes. These contigs are clustered with no known viral genomes, and over 2/3 of the ORFs on the viral contigs encode no known functions. Furthermore, most of the complete viral contigs show limited similarity to known viral genomes in genome organization. Most of the classified viral contigs are derived from dsDNA viruses belonging to the order Caudovirales , including primarily members of the families Myoviridae , Podoviridae and Siphoviridae . Most of these viruses infect Proteobacteria and, less frequently, Planctomycetes , Firmicutes , Chloroflexi , etc. Auxiliary metabolic genes (AMGs), present in abundance on the viral contigs, appear to function in modulating the host ability to sense environmental gradients and community changes, and to uptake and metabolize nutrients.

PapA , a peptidoglycan‐associated protein, interacts with OmpC and maintains cell envelope integrity - Yun‐Hao Wang; Hong‐He Chen; Zhou Huang; Xiao‐Jing Li; Nan Zhou; Chang Liu; Cheng‐Ying Jiang; De‐Feng Li; Shuang‐Jiang Liu (Environmental Microbiology, 2021)
Summary The bacterial cell envelope is critical to support and maintain cellular life. In Gram‐negative bacterial cells, the outer membrane and the peptidoglycan layer are two important parts of the cell envelope and they harbour abundant proteins. Here, we report the identification and characterization of a previously unknown p eptidoglycan‐ a ssociated p rotein, PapA, from the Gram‐negative Comamonas testosteroni . PapA bound peptidoglycan with its C‐terminal domain and interacted with the outer‐membrane porin OmpC. The PapA‐OmpC complex riveted the outer membrane and the peptidoglycan layer, and played a role in maintaining cell envelope integrity. When papA was disrupted, the mutant CNB‐1Δ papA apparently had an outer membrane partly separated from the peptidoglycan layer. Phenotypically, the mutant CNB‐1Δ papA lost chemotactic responses and had longer lag‐phase of growth, less flagellation and higher sensitivity to harsh environments. Totally, 1093 functionally unknown PapA homologues were identified from the public NR protein database and they were mainly distributed in Burkholderiales of Betaproteobacteria. Our finding provides a clue that the PapA homologous proteins might function as a rivet to maintain cell envelope integrity in those Gram‐negative bacteria.

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Morphology and Molecular Phylogeny of Four Trachelocercid Ciliates (Protozoa, Ciliophora, Karyorelictea) Found in Marine Coastal Habitats of Northern China, With Description of a New Genus, Two New Species and a New Combination - Mingzhen Ma; Yuqing Li; Honggang Ma; Khaled A. S. Al-Rasheid; Alan Warren; Yurui Wang; Ying Yan (Frontiers in Marine Science, 2021)
The morphology of four trachelocercid ciliates, Paratrachelocerca typica gen. nov., spec. nov., Trachelolophos monocaryon ( Dragesco, 1965 ) comb. nov. (original combination: Tracheloraphis monocaryon Dragesco, 1965 ), Tracheloraphis katzae spec. nov., and Tracheloraphis colubis ( Kahl, 1933 ) Xu et al., 2011 were studied in live and protargol-stained specimens. All samples were isolated from the intertidal zone of sandy beaches at Qingdao, China. The new genus Paratrachelocerca can be distinguished from other trachelocercid genera mainly by the three circumoral kineties each composed of a row of dikinetids and the absence of a brosse or ciliary tuft in the oral cavity. The detailed investigation on the poorly described Tracheloraphis monocaryon ( Dragesco, 1965 ) reveals that its oral infraciliature includes one uninterrupted circumoral kinety and a conspicuous ciliary tuft in the center of the oral cavity, which is consistent with the genus Trachelolophos rather than Tracheloraphis . Therefore, this species is transferred to Trachelolophos as Trachelolophos monocaryon ( Dragesco, 1965 ) comb. nov. Tracheloraphis katzae spec. nov. can be recognized by the combination of its minute brownish cortical granules and 9–15 somatic kineties. The small subunit (SSU) rDNA of each species was sequenced for the first time. Phylogenetic analyses of the SSU rDNA show that Paratrachelocerca typica gen. nov., spec. nov. clusters with Apotrachelocerca arenicola ( Kahl, 1933 ) Xu et al., 2011 in a group that is sister to all other trachelocercids.

Satellite Remote Sensing for Estimating PM2.5 and Its Components - Ying Li; Shuyun Yuan; Shidong Fan; Yushan Song; Zihao Wang; Zujun Yu; Qinghua Yu; Yiwen Liu (Current Pollution Reports, 2021)

The Ocean Heat Content Changes in the South China Sea due to Tropical Cyclones with Different Tracks - Long Yu; Jia Sun; Zhenli Hui; Xuejun Xiong; Shanshan Jin; Lu Wang; Guangbing Yang; Yanliang Guo; Xia Ju; Liang Chen; Xiaomin Hu; Ying Li (Pure and Applied Geophysics, 2021)

Progressive Fine Integrated Geophysical Method for Karst Detection During Subway Construction - Maoxin Su; Ying Zhao; Yiguo Xue; Peng Wang; Teng Xia; Kai Zhang; Congcong Li (Pure and Applied Geophysics, 2021)

Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human - Ya-Xin Fan; Yuan-Cheng Chen; Yi Li; Ji-Cheng Yu; Xing-Chen Bian; Xin Li; Wan-Zhen Li; Bei-Ning Guo; Hai-Lan Wu; Xiao-Fen Liu; Yu Wang; Xiao-Yong Xu; et al. (Pharmaceutical Research, 2021)

Different roles of Numb-p72 and Numb-p65 on the trafficking of metabotropic glutamate receptor 5 - Na Wang; Dan-Dan Wang; Xiaolin Hou; Xiumao Li; Ying Shen (Molecular Biology Reports, 2021)

7,8-Dihydroxyflavone Alleviates Anxiety-Like Behavior Induced by Chronic Alcohol Exposure in Mice Involving Tropomyosin-Related Kinase B in the Amygdala - Na Wang; Xing Liu; Xin-Tong Li; Xin-Xin Li; Wei Ma; Yan-Min Xu; Yong Liu; Qing Gao; Tao Yang; Hongxuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2021)

A Novel Fluorescent Probe Based on Pyrazole-Pyrazoline for Fe (III) Ions Recognition - Ying-Peng Zhang; Xiang-Fang Li; Yun-Shang Yang; Jing-Li Wang; Yu-Chen Zhao; Ji-Jun Xue (Journal of Fluorescence, 2021)

LncRNA TUG1 regulates the balance of HuR and miR-29b-3p and inhibits intestinal epithelial cell apoptosis in a mouse model of ulcerative colitis - Yuxi Tian; Ying Wang; Fujun Li; Junwen Yang; Yan Xu; Miao Ouyang (Human Cell, 2021)

The impact of urbanization and consumption patterns on China’s black carbon emissions based on input–output analysis and structural decomposition analysis - Zhongci Deng; Ping Kang; Zhen Wang; Xiaoling Zhang; Weijie Li; Yihan Ou; Yu Lei; Ying Dang; Zhongren Deng (Environmental Science and Pollution Research, 2021)

Phytochemical constituents, chemotaxonomic significance and anti-arthritic effect of Eucommia ulmoides Oliver staminate flowers - Rui Li; Lanlan Nie; Qing Wang; Danwei Ouyang; Lei Zhang; Ying Yuan; Yanlong Hong; Jianying Wang; Xiao Hu (Natural Product Research, 2020)

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Stability Assessment of Intracranial Aneurysms Using Machine Learning Based on Clinical and Morphological Features - Wei Zhu; Wenqiang Li; Zhongbin Tian; Yisen Zhang; Kun Wang; Ying Zhang; Jian Liu; Xinjian Yang (Translational Stroke Research, 2020)

TGF-β regulation of microRNA miR-497-5p and ocular lens epithelial cell mesenchymal transition - Jinda Wang; Jingshang Zhang; Ying Xiong; Jing Li; Xiaoxia Li; Jing Zhao; Guyu Zhu; Hailong He; Yusufu Mayinuer; Xiuhua Wan (Science China Life Sciences, 2020)

Natural products development under epigenetic modulation in fungi - Chi-Ying Li; Yu-Ming Chung; Yang-Chang Wu; Attila Hunyadi; Clay C. C. Wang; Fang-Rong Chang (Phytochemistry Reviews, 2020)

Connexin 36 Mediates Orofacial Pain Hypersensitivity Through GluK2 and TRPA1 - Qian Li; Tian-Le Ma; You-Qi Qiu; Wen-Qiang Cui; Teng Chen; Wen-Wen Zhang; Jing Wang; Qi-Liang Mao-Ying; Wen-Li Mi; Yan-Qing Wang; Yu-Xia Chu (Neuroscience Bulletin, 2020)

AMPK Ameliorates Tau Acetylation and Memory Impairment Through Sirt1 - Lin Wang; Fang-Xiao Shi; Na Li; Yun Cao; Ying Lei; Jian-Zhi Wang; Qing Tian; Xin-Wen Zhou (Molecular Neurobiology, 2020)

Clinical characteristics and plasma antibody titer of patients with COVID-19 in Zhejiang, China - Wei-ling Xiang; Jing-jing Cheng; Lian-peng Wu; Bing-yu Chen; Wen-xin Li; Dan-ying Qiu; Wei Zhang; Fei-hang Ge; Dong Chen; Zhen Wang (Journal of Zhejiang University-SCIENCE B, 2020)

Effects of Short-Term Application of Chemical and Organic Fertilizers on Bacterial Diversity of Cornfield Soil in a Karst Area - Ying Li; Xiuming Liu; Lin Zhang; Yuanhuan Xie; Xianli Cai; Shijie Wang; Bin Lian (Journal of Soil Science and Plant Nutrition, 2020)

High-throughput sequencing reveals the molecular mechanisms determining the stay-green characteristic in soybeans - Cheng Wang; Le Gao; Run Zhi Li; Ye Wang; Yang Ying Liu; Xin Zhang; Hao Xie (Journal of Biosciences, 2020)

Transcriptome-wide identification and profiling of miRNAs in a stress-tolerant conifer Sabina chinensis - Xian-Ge Hu; Shan-Shan Zhou; Ying Yang; Hui Liu; Shrestha Anil; Qing Wang; Wei Zhao; Qiong Gao; Yousry A El-Kassaby; Tongli Wang; Yue Li; Jian-Feng Mao (Journal of Biosciences, 2020)

Comparison Between the Gut Microbiota in Different Gastrointestinal Segments of Large-Tailed Han and Small-Tailed Han Sheep Breeds with High-Throughput Sequencing - Guangli Yang; Shuhong Zhang; Zhiqiang Li; Jie Huang; Yan Liu; Ying Liu; Qiankun Wang; Xiangyu Li; Yongfeng Yan; Ming Li (Indian Journal of Microbiology, 2020)

Update on recommendations for the diagnosis and treatment of SARS-CoV-2 infection in children - Hongjun Miao; Han Li; Yinying Yao; Mingfu Wu; Chao Lu; Jun Wang; Man Tian; Ying Li; Peiliang Luo; Jianhui Gu; Bin Yuan; Shouchuan Wang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2020)
Since the outbreak of novel coronavirus infection pneumonia in Wuhan City, China, in late 2019, such cases have been gradually reported in other parts of China and abroad. Children have become susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) because of their immature immune function. As the outbreak has progressed, more cases of novel coronavirus infection/pneumonia in children have been reported. Compared with adults, the impact of SARS-CoV-2 infection in children is less severe, with a lower incidence and susceptibility in children, which results in fewer children being tested, thereby underestimating the actual number of infections. Therefore, strengthening the diagnosis of the disease is particularly important for children, and early and clear diagnosis can determine treatment strategies and reduce the harm caused by the disease to children. According to the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards ( trial version 7 ) issued by National Health Committee and the latest diagnosis and treatment strategies for novel coronavirus infection pneumonia in children, this review summarizes current strategies on diagnosis and treatment of SARS-CoV-2 infection in children.

Ecological risk assessment of heavy metals in fish from the Dianchi Lake, China using the integrated biomarker response approach - Ying Gao; Li Fang; Qian Qian Xiang; Di Wang; Liu Yong Ding; Cheng Zhi Ding; Li Qiang Chen (Environmental Science and Pollution Research, 2020)

Psychological symptoms in Chinese nurses may be associated with predisposition to chronic disease: a cross-sectional study of suboptimal health status - Jinxiu Zhu; Wenjuan Ying; Li Zhang; Gangyi Peng; Weiju Chen; Enoch Odame Anto; Xueqing Wang; Nan Lu; Shanshan Gao; Guihai Wu; Jingyi Yan; Jianfeng Ye; et al. (EPMA Journal, 2020)
Background Suboptimal health status (SHS) is a reversible state between ideal health and illness and it can be effectively reversed by risk prediction, disease prevention, and personalized medicine under the global background of predictive, preventive, and personalized medicine (PPPM) concepts. More and more Chinese nurses have been troubled by psychological symptoms (PS). The correlation between PS and SHS is unclear in nurses. The purpose of current study is to investigate the prevalence of SHS and PS in Chinese nurses and the relationship between SHS and PS along with predisposing factors as well as to discuss the feasibility of improving health status and preventing diseases according to PPPM concepts in Chinese nurses. Methods A cross-sectional study was conducted with the cluster sampling method among 9793 registered nurses in Foshan city, China. SHS was evaluated with the Suboptimal Health Status Questionnaire-25 (SHSQ-25). Meanwhile, the PS of depression and anxiety were evaluated with Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) self-assessment questionnaires. The relationship between PS and SHS in Chinese nurses was subsequently analyzed. Results Among the 9793 participants, 6107 nurses were included in the final analysis. The prevalence of SHS in the participants was 74.21% (4532/6107) while the symptoms of depression and anxiety were 47.62% (2908/6107) and 24.59% (1502/6107) respectively. The prevalence of SHS in the participants with depression and anxiety was significantly higher than those without the symptoms of depression (83.3% vs 16.7%, P < 0.001) and anxiety (94.2% vs 5.8%, P < 0.0001). The ratio of exercise habit was significantly lower than that of non-exercise habit (68.8% vs 78.4%, P < 0.001) in SHS group. Conclusions There is a high prevalence of SHS and PS in Chinese nurses. PS in Chinese nurses are associated with SHS. Physical exercise is a protective factor for SHS and PS so that the exercise should be strongly recommended as a valuable preventive measure well in the agreement with PPPM philosophy. Along with SDS and SAS, SHSQ-25 should also be highly recommended and applied as a novel predictive/preventive tool for the health measures from the perspectives of PPPM in view of susceptible population and individual screening, the predisposition to chronic disease preventing, personalization of intervention, and the ideal health state restoring.

Using sowing date management to promote micronutrient quality and alleviate cadmium accumulation in rice grains - Lin-lin Shi; Ming-xing Shen; Hong-jun Wu; Chang-ying Lu; Li-juan Mei; Xin-lian Zhu; Hai-hou Wang; Yun-Sheng Song (Cereal Research Communications, 2020)

Correction to: The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans - Jin-Yan Liu; Bing Wei; Ying Wang; Ce Shi; Wen-Jing Li; Yue Zhao; Ling-Ning Meng; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2020)

The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans - Jin-Yan Liu; Bing Wei; Ying Wang; Ce Shi; Wen-Jing Li; Yue Zhao; Ling-Ning Meng; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2020)

Dynamic network connectivity predicts subjective cognitive decline: the Sino-Longitudinal Cognitive impairment and dementia study - Guozhao Dong; Liu Yang; Chiang-shan R. Li; Xiaoni Wang; Yihe Zhang; Wenying Du; Ying Han; Xiaoying Tang (Brain Imaging and Behavior, 2020)

Patterns of intrinsic brain activity in essential tremor with resting tremor and tremor-dominant Parkinson’s disease - Jun-ying Li; Zhong-jiao Lu; Xue-ling Suo; Nan-nan Li; Du Lei; Ling Wang; Jia-xin Peng; Li-ren Duan; Jing Xi; Yi Jiang; Qi-yong Gong; Rong Peng (Brain Imaging and Behavior, 2020)

Cortical 3-hinges could serve as hubs in cortico-cortical connective network - Tuo Zhang; Xiao Li; Xi Jiang; Fangfei Ge; Shu Zhang; Lin Zhao; Huan Liu; Ying Huang; Xianqiao Wang; Jian Yang; Lei Guo; Xiaoping Hu; et al. (Brain Imaging and Behavior, 2020)
Mapping the relation between cortical convolution and structural/functional brain architectures could provide deep insights into the mechanisms of brain development, evolution and diseases. In our previous studies, we found a unique gyral folding pattern, termed a 3-hinge, which was defined as the conjunction of three gyral crests. The uniqueness of the 3-hinge was evidenced by its thicker cortex and stronger fiber connections than other gyral regions. However, the role that 3-hinges play in cortico-cortical connective architecture remains unclear. To this end, we conducted MRI studies by constructing structural cortico-cortical connective networks based on a fine-granular cortical parcellation, the parcels of which were automatically labeled as 3-hinge, 2-hinge (ordinary gyrus) or sulcus. On human brains, 3-hinges possess significantly higher degrees, strengths and betweennesses than 2-hinges, suggesting that 3-hinges could serve more like hubs in the cortico-cortical connective network. This hypothesis gains supports from human functional network analyses, in which 3-hinges are involved in more global functional networks than ordinary gyri. In addition, 3-hinges could serve as ‘connector’ hubs rather than ‘provincial’ hubs and they account for a dominant proportion of nodes in the high-level ‘backbone’ of the network. These structural results are reproduced on chimpanzee and macaque brains, while the roles of 3-hinges as hubs become more pronounced in higher order primates. Our new findings could provide a new window to the relation between cortical convolution, anatomical connection and brain function.

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

LncRNA A2M-AS1 lessens the injury of cardiomyocytes caused by hypoxia and reoxygenation via regulating IL1R2 - Xue-Lian Song; Fei-Fei Zhang; Wen-Jing Wang; Xin-Ning Li; Yi Dang; Ying-Xiao Li; Qian Yang; Mei-Jing Shi; Xiao-Yong Qi (Genes & Genomics, 2020)

The function and mechanism of ferroptosis in cancer - Ying Wang; Zihao Wei; Keran Pan; Jing Li; Qianming Chen (Apoptosis, 2020)

Prediction and Identification of Epitopes in the Emy162 Antigen of Echinococcus multilocularis - Ming-Quan Pang; Feng Tang; Hai-Jiu Wang; Ying Zhou; Li Ren; Run-Le Li; Hu Zhou; Chen-Fei Wan; Chuan-Chuan Liu; Cai-Rang Yangdan; Hai-Ning Fan (Acta Parasitologica, 2020)

Prevalence of Cryptosporidium Infection in the Global Population: A Systematic Review and Meta-analysis - Shurong Dong; Ya Yang; Yingjian Wang; Dongjian Yang; Yu Yang; Ying Shi; Chunlin Li; Linhan Li; Yue Chen; Qingwu Jiang; Yibiao Zhou (Acta Parasitologica, 2020)

Role of enterotoxigenic Escherichia coli prophage in spreading antibiotic resistance in a porcine‐derived environment - Mianzhi Wang; Zhenling Zeng; Fengwei Jiang; Ying Zheng; Huigang Shen; Nubia Macedo; Yongxue Sun; Orhan Sahin; Ganwu Li (Environmental Microbiology, 2020)
Summary Enterotoxigenic Escherichia coli (ETEC) cause acute secretory diarrhoea in pigs, posing a great economic loss to the swine industry. This study analysed the prevalence and genetic characteristics of prophages from 132 ETEC isolates from symptomatic pigs to determine their potential for spreading antibiotic resistance. A total of 1105 potential prophages were identified, and the distribution of the genome size showed three ‘overlapping’ trends. Similarity matrix comparison showed that prophages correlated with the ETEC lineage distribution, and further identification of these prophages corroborated the lineage specificity. In total, 1206 antibiotic resistance genes (ARGs) of 52 different categories were identified in 132 ETEC strains; among these, 2.65% (32/1206) of ARGs were found to be carried by prophages. Analysis of flanking sequences showed that almost all the ARGs could be grouped into two types: ‘ bla TEM‐1B ’ and ‘classic class 1 integron (IntI1)’. They co‐occurred with a strictly conserved recombinase and transposon Tn 3 family but with a difference: the ‘ bla TEM‐1B type’ prophages exhibited a classic Tn 2 transposon structure with 100% sequence identity, whereas the ‘IntI1 type’ co‐occurred with the TnAs 2 transposon with only 84% sequence identity. These results imply that ARGs might be pervasive in natural bacterial populations through transmission by transposable bacteriophages.

Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions - Xiuxiu Li; Zhuo Chen; Guomin Zhang; Hongwei Lu; Peng Qin; Ming Qi; Ying Yu; Bingke Jiao; Xianfeng Zhao; Qiang Gao; Hao Wang; Yunyu Wu; et al. (Science China Life Sciences, 2020)

Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior - Meng-Jia Zhu; Jing Shi; Yong Chen; Guobing Huang; Xiong-Wei Zhu; Sam Zhang; Xian-Feng Huang; Guo-Qiang Song; Han-Ting Zhang; Heng-Ming Ke; James M. O’Donnell; Li-Qun Wang; et al. (Psychopharmacology, 2020)

Removal of antipyrine through two-dimensional and three-dimensional electrolysis: comparison, modification, and improvement - Pengxiao Liu; Xu Wang; Jing Lu; Ying Li; Bin Hou; Ling Feng (Environmental Science and Pollution Research, 2020)

The Effect of Iodine-Containing Vitamin Supplementation During Pregnancy on Thyroid Function in Late Pregnancy and Postpartum Depression in an Iodine-Sufficient Area - Zixiao Wang; Chenyang Li; Ying Teng; Yunping Guan; Li Zhang; Xi Jia; Dandan Cui; Jing Li; Haixia Guan (Biological Trace Element Research, 2020)

Effects of disruption of Grapholita molesta (Lepidoptera: Tortricidae) using sex pheromone on moth pests and insect communities in orchards - Weina Kong; Yi Wang; Yongfu Guo; Xiaohan Chai; Guofei Niu; Ying Li; Ruiyan Ma; Jie Li (Applied Entomology and Zoology, 2020)

Development of Aggregation-Caused Quenching Probe-Loaded Pressurized Metered-Dose Inhalers with Fluorescence Tracking Potentials - Wenhua Wang; Zhengwei Huang; Ke Xue; Jiaye Li; Wenhao Wang; Jingyi Ma; Cheng Ma; Xuequn Bai; Ying Huang; Xin Pan; Chuanbin Wu (AAPS PharmSciTech, 2020)

Serological characteristics of COVID-19 patients - Mi Zhou; Jing Zhong; Lei Bi; Pengcheng Shang; Yan Xing; Bo Wang; Jianlan He; Ying Xu; Tao Luo; Maohua Ma; Qingfeng Li (Infectious Diseases, 2020)

Cerebral Organoids Repair Ischemic Stroke Brain Injury - Shu-Na Wang; Zhi Wang; Tian-Ying Xu; Ming-He Cheng; Wen-Lin Li; Chao-Yu Miao (Translational Stroke Research, 2020)
Stroke is the second leading cause of death and main cause of disability worldwide, but with few effective therapies. Although stem cell-based therapy has been proposed as an exciting regenerative medicine strategy for brain injury, there are limitations. The developed cerebral organoids (COs) represent a promising transplantation source for stroke that remains to be answered. Here, we transplanted COs at 55 days and explored the feasibility in the rat middle cerebral artery occlusion (MCAO) model of stroke. COs transplantation at 6 h or even 24 h after MCAO significantly reduces brain infarct volume and improves neurological motor function. Transplanted COs show the potential of multilineage differentiation to mimic in vivo cortical development, support motor cortex region-specific reconstruction, form neurotransmitter-related neurons, and achieve synaptic connection with host brain via in situ differentiation and cell replacement in stroke. Cells from transplanted COs show extensive migration into different brain regions along corpus callosum. The mechanisms underlying COs transplantation therapy are also associated with enhanced neurogenesis, synaptic reconstruction, axonal regeneration and angiogenesis, and decreased neural apoptosis with more survival neurons after stroke. Moreover, COs transplantation promotes predominantly exogenous neurogenesis in the transplantation periphery of ipsilateral cortex and predominantly endogenous neurogenesis in the hippocampus and subventricular zone. Together, we demonstrate the efficacy and underlying mechanisms of COs transplantation in stroke. This preliminary but promising study provides first-hand preclinical evidence for COs transplantation as a potential and effective intervention for stroke treatment.

New Value-Added Sugar and Brown Sugar Products from Sugarcane: A Commercial Approach - Liu Yang; Shi-Yan Shen; Zhi-Neng Wang; Ting Yang; Jia-Wen Guo; Rui-Yun Hu; Yan-Fang Li; David M. Burner; Xiong-Mei Ying (Sugar Tech, 2020)

Genome-wide transcriptome and proteome profiles indicate an active role of alternative splicing during de-etiolation of maize seedlings - Zhen Yan; Zhuo Shen; Zhe Li; Qing Chao; Lei Kong; Zhi-Fang Gao; Qing-Wei Li; Hai-Yan Zheng; Cai-Feng Zhao; Cong-Ming Lu; Ying-Wei Wang; Bai-Chen Wang (Planta, 2020)

FtMYB18 acts as a negative regulator of anthocyanin/proanthocyanidin biosynthesis in Tartary buckwheat - Qixin Dong; Haixia Zhao; Yunji Huang; Ying Chen; Min Wan; Zixian Zeng; Panfeng Yao; Chenglei Li; Xiaoli Wang; Hui Chen; Qi Wu (Plant Molecular Biology, 2020)

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway - Jia-Ru Wang; Tian-Zhu Li; Cheng Wang; Shu-Mei Li; Ying-Hua Luo; Xian-Ji Piao; Yu-Chao Feng; Yi Zhang; Wan-Ting Xu; Yu Zhang; Tong Zhang; Shi-Nong Wang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

IL-6 induces tumor suppressor protein tyrosine phosphatase receptor type D by inhibiting miR-34a to prevent IL-6 signaling overactivation - Fan Zhang; Bo Wang; Tao Qin; Lu Wang; Qingqing Zhang; Ying Lu; Bo Song; Xiaotang Yu; Lianhong Li (Molecular and Cellular Biochemistry, 2020)

KIF15 contributes to cell proliferation and migration in breast cancer - Xiaokang Gao; Linhai Zhu; Xuan Lu; Ying Wang; Ruiqing Li; Guoqin Jiang (Human Cell, 2020)

The mRNA expression of ompF, invA and invE was associated with the ciprofloxacin-resistance in Salmonella - Xiongwei Du; Ying Liu; Xiaojie Sun; Jianmei Zhao; Juan Wang; Jianping Li; Xuelian Liu; Junwei Wang; Ye Li (Archives of Microbiology, 2020)

Antibacterial and antiparasitic activities analysis of a hepcidin-like antimicrobial peptide from Larimichthys crocea - Libing Zheng; Yuan Li; Jun Wang; Ying Pan; Jia Chen; Weiqiang Zheng; Longshan Lin (Acta Oceanologica Sinica, 2020)

Plant resistance and leaf chemical characteristic jointly shape phyllosphere bacterial community - Tian Xueliang; Xu Dan; Sun Tingting; Zhao Songyu; Li Ying; Wang Diandong (World Journal of Microbiology and Biotechnology, 2020)

Atmospheric wet and dry deposition of dissolved inorganic nitrogen to the South China Sea - Ying Gao; Lifang Wang; Xianghui Guo; Yi Xu; Li Luo (Science China Earth Sciences, 2020)

Correction to: LncRNA NONRATT021972 involved the pathophysiologic processes mediated by P2X7 receptors in stellate ganglia after myocardial ischemic injury - Lifang Zou; Guihua Tu; Wei Xie; Shiyao Wen; Qiuyu Xie; Shuangmei Liu; Guilin Li; Yun Gao; Hong Xu; Shouyu Wang; Yun Xue; Bing Wu; et al. (Purinergic Signalling, 2020)

Secreted frizzled-related protein 2 prevents pressure-overload-induced cardiac hypertrophy by targeting the Wnt/β-catenin pathway - Wen-Ying Wei; Qing Zhao; Wen-zhong Zhang; Mao-jing Wang; Yan Li; Shi-zhong Wang; Ning Zhang (Molecular and Cellular Biochemistry, 2020)

Characteristics of chemotherapy-induced diabetes mellitus in acute lymphoblastic leukemia patients - Shan-shan Suo; Chen-ying Li; Yi Zhang; Jing-han Wang; Yin-jun Lou; Wen-juan Yu; Jie Jin (Journal of Zhejiang University-SCIENCE B, 2020)

Anti-inflammatory canthin-6-one alkaloids from the roots of Thailand Eurycoma longifolia Jack - Ying Zhang; Wei Zhao; Jingya Ruan; Nuttapong Wichai; Zheng Li; Lifeng Han; Yi Zhang; Tao Wang (Journal of Natural Medicines, 2020)

Developing the relationship between metal ionic characters and ecological risk assessment screening values using QICAR - Zhitao Li; Xiaoqi Meng; Ying Wang; Xuedong Wang (Environmental Science and Pollution Research, 2020)

Colorimetric detection of Hg2+ using gold nanoparticles synthesized by Trichosporon montevideense WIN - Rouyi Wang; Henglin Zhang; Xiuhong Zhang; Zheng Li; Ying Yang; Ru Zheng; Yuanyuan Qu (Biotechnology Letters, 2020)

Genesis of the Linghu Au deposit in Xiaoqinling Region, Henan province, China: Constraints from fluid inclusions and isotope systematics - Wei Zeng; Zhi-gao Wang; Duo Wan; Feng-yue Sun; Cheng-dong Li; Reng-an Yu; Jia-ying Wang; Jian-chang Xu (Arabian Journal of Geosciences, 2020)

Production, safety, health effects and applications of diacylglycerol functional oil in food systems: a review - Yee-Ying Lee; Teck-Kim Tang; Eng-Tong Phuah; Chin-Ping Tan; Yong Wang; Ying Li; Ling-Zhi Cheong; Oi-Ming Lai (Critical Reviews in Food Science and Nutrition, 2020)

Positive RT-PCR in urine from an asymptomatic patient with novel coronavirus 2019 infection: a case report - Jian-guo Ren; Dong-yan Li; Chang-fei Wang; Jian-hua Wu; Ying Wang; Yu-jing Sun; Qian Zhang; Yao-yong Wang; Xin-jian Chang (Infectious Diseases, 2020)

A fundamental theorem for eco-environmental surface modelling and its applications - Tianxiang Yue; Na Zhao; Yu Liu; Yifu Wang; Bin Zhang; Zhengping Du; Zemeng Fan; Wenjiao Shi; Chuanfa Chen; Mingwei Zhao; Dunjiang Song; Shihai Wang; et al. (Science China Earth Sciences, 2020)

A novel plant protein-disulfide isomerase participates in resistance response against the TYLCV in tomato - Tong Li; Ya-Hui Wang; Ying Huang; Jie-Xia Liu; Guo-Ming Xing; Sheng Sun; Sen Li; Zhi-Sheng Xu; Ai-Sheng Xiong (Planta, 2020)

Impaired Parahippocampal Gyrus–Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease - Lin Zhu; Zan Wang; Zhanhong Du; Xinyang Qi; Hao Shu; Duan Liu; Fan Su; Qing Ye; Xuemei Liu; Zheng Zhou; Yongqiang Tang; Ru Song; et al. (Neuroscience Bulletin, 2020)

Upregulation of AMPK Ameliorates Alzheimer’s Disease-Like Tau Pathology and Memory Impairment - Lin Wang; Na Li; Fang-Xiao Shi; Wei-Qi Xu; Yun Cao; Ying Lei; Jian-Zhi Wang; Qing Tian; Xin-Wen Zhou (Molecular Neurobiology, 2020)

The Probability and Sensitivity Analysis of Slope Stability Under Seepage Based on Reliability Theory - Tao Li; Guodong Liu; Cong Wang; Xuwang Wang; Ying Li (Geotechnical and Geological Engineering, 2020)

Urban residential land expansion and agglomeration in China: a spatial analysis approach - Xiaofeng Zhao; Mingming Zhang; Ying Li; Xianjin Huang; Baiyuan Wang; Lin Zhang (Environment, Development and Sustainability, 2020)

Pseudomonas Saliphila sp. nov., a Bacterium Isolated from Oil-Well Production Water in Qinghai Oilfield of China - Xiao-Juan Zhang; Hong-Can Liu; Yu-Guang Zhou; Xiao-Lei Wu; Yong Nie; Qi-Rui Li; Mei-Zhu Wang; Liang Zhao; Man Cai; Ying-Qian Kang (Current Microbiology, 2020)

Naphthalene exerts non-target effects on the abundance of active fungi by stimulating basidiomycete abundance - Li-ying Lan; Li Zhang; Ya Shen; Jian Zhang; Wan-qin Yang; Zhen-feng Xu; Yang Liu; Shu-qin He; Wei Zhou; Han Li; Li-xia Wang; Si-ning Liu; et al. (Journal of Mountain Science, 2020)

Generation of a porcine reproductive and respiratory syndrome virus expressing a marker gene inserted between ORF4 and ORF5a - Yuxu Wang; Wei He; Qingqing Li; Xin Xie; Nian Qin; Hao Wang; Jiabin Huang; Siyuan Lin; Kang Ouyang; Ying Chen; Weijian Huang; Zuzhang Wei (Archives of Virology, 2020)

Impacts of climate anomalies on the interannual and interdecadal variability of autumn and winter haze in North China: A review - Jing Wang; Yanju Liu; Yihui Ding; Ping Wu; Zhiwei Zhu; Ying Xu; Qiaoping Li; Yingxian Zhang; Jinhai He; Julian X. L. Wang; Li Qi (International Journal of Climatology, 2020)
From the perspectives of remote sensing and climatic factors like surface meteorological parameters, large‐scale atmospheric circulations, and external forcing factors (EFFs), the authors synthesize and review spatiotemporal variations of PM 2.5 over North China and how climate anomalies affect autumn and winter haze variability in North China according to recent studies. This review focuses on both interannual and interdecadal timescales. It is shown that circulations play an important role in influencing haze variability. Atmospheric circulations, which would be modulated by EFFs like sea surface temperature, sea ice, and snowpack, can affect the climate variability in haze over North China via modulation of surface‐layer parameters that are closely connected with the haze phenomenon. Therefore, EFFs are deemed significant factors impacting the climate variability of haze over North China, serving as paramount precursory signals for haze prediction. Furthermore, this paper suggests potential future research directions for haze variability studies in North China on the basis of summarizing and concluding the associated processes/mechanisms on how climatic factors affect haze variability, which could provide reference for treating and forecasting in situ hazy conditions.

Isolation and identification of two new compounds from the Penicillium sp. SYPF7381 - Qing-Mei Feng; Xing-Yu Li; Bing-Xin Li; Tian-Yuan Zhang; Hai-Feng Wang; Meng-Yue Zhang; Ying-Ying Wu; Gang Chen; Yi-Xuan Zhang; Yue-Hu Pei (Natural Product Research, 2020)

A new triterpenoid glucoside from Leucas zeylanica - Guang-Ying Chen; Bin Zhang; Ting Zhao; Najat Nidhal; Wang Jia-Li; Xue-Ming Zhou; Dai Chun-Yan (Natural Product Research, 2020)

Characterization of viromes within mosquito species in China - Jiang Du; Fan Li; Yelin Han; Shihong Fu; Bo Liu; Nan Shao; Haoxiang Su; Weijia Zhang; Dandan Zheng; Wenwen Lei; Jie Dong; Lilian Sun; et al. (Science China Life Sciences, 2020)

Decreased sustained attention, processing speed and verbal learning memory in patients with insomnia in Chinese young and middle-aged adults: a cross-sectional study - Xie Chen; Cai-Lan Hou; Shi-Bin Wang; Zhuo-Hui Huang; Ying-Hua Huang; Xue-Li Li; Fu-Jun Jia (Sleep and Biological Rhythms, 2020)

The trichome-specific acetolactate synthase NtALS1 gene, is involved in acylsugar biosynthesis in tobacco (Nicotiana tabacum L.) - Ai-Xia Chang; Biao Chen; Ai-Guo Yang; Ri-Sheng Hu; Quan-Fu Feng; Ming Chen; Xiao-Ning Yang; Cheng-Gang Luo; Yang-Yang Li; Yuan-Ying Wang (Planta, 2020)

Heterogeneity in short-term allocation of carbon to roots of Pinus tabuliformis seedlings and root respiration under drought stress - Ying Liu; Peng Li; Lie Xiao; Wen Wang; Kunxia Yu; Peng Shi (Plant and Soil, 2020)

Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort - Wei-Wei Li; Zhen Wang; Dong-Yu Fan; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Ling Li; Heng Yang; Yu-Hui Liu; Xian-Le Bu; Wang-Sheng Jin; Fan Zeng; et al. (Neuroscience Bulletin, 2020)

Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family - Juan Zhang; Yanjun Liu; Ming Li; Xiaoxu Ge; Ying Wang; Xin Huang; Di Yang; Rong Zhang; Yating Chen; Ming Lu; Jun Yin; Mingqiang Song; et al. (Molecular and Cellular Biochemistry, 2020)

Crosstalk between PKC and MAPK pathway activation in cardiac fibroblasts in a rat model of atrial fibrillation - Wei-hua Guo; Xian Wang; Mei-sheng Shang; Zhe Chen; Qi Guo; Li Li; Hai-ying Wang; Rong-hui Yu; Chang-sheng Ma (Biotechnology Letters, 2020)

RETRACTED ARTICLE: CiRS-126 inhibits proliferation of ovarian granulosa cells through targeting the miR-21-PDCD4-ROS axis in a polycystic ovarian syndrome model - Jiafeng Lu; Ying Xue; Yuhang Wang; Yang Ding; Qinyan Zou; Min Pan; Longwei Qiao; Chunhua Zhang; Qinyu Ge; Ting Wang; Hong Li (Cell and Tissue Research, 2020)

Stability Analysis of the Arch Crown of a Large-Scale Underground Powerhouse During Excavation - Zhonghua Hu; Nuwen Xu; Biao Li; Ying Xu; Jian Xu; Kai Wang (Rock Mechanics and Rock Engineering, 2020)

Long-Term Greenhouse Cucumber Production Alters Soil Bacterial Community Structure - Xing Liu; Yujiao Li; Xiujuan Ren; Bihua Chen; Ying Zhang; Changwei Shen; Fei Wang; Dafu Wu (Journal of Soil Science and Plant Nutrition, 2020)

Legumain promotes fibrogenesis in chronic pancreatitis via activation of transforming growth factor β1 - Ying-Chun Ren; Qiuyan Zhao; Yan He; Bin Li; Zengkai Wu; Juanjuan Dai; Li Wen; Xingpeng Wang; Guoyong Hu (Journal of Molecular Medicine, 2020)

Linking lipid accumulation and photosynthetic efficiency in Nannochloropsis sp. under nutrient limitation and replenishment - Tao Li; Weinan Wang; Chaojie Yuan; Ying Zhang; Jin Xu; Helong Zheng; Wenzhou Xiang; Aifen Li (Journal of Applied Phycology, 2020)

Inhibition of glycolysis ameliorate arthritis in adjuvant arthritis rats by inhibiting synoviocyte activation through AMPK/NF-кB pathway - Ying Wang; Hao Xian; Jiajia Qi; Fang Wei; Xiu Cheng; Sha Li; Qing Wang; Zhaoyang Liu; Yun Yu; Jing Zhou; Xiaojin Sun; Hao Liu; et al. (Inflammation Research, 2020)

LncRNA SNHG5 regulates SOX4 expression through competitive binding to miR-489-3p in acute myeloid leukemia - Xiaoyang Ying; Wanggang Zhang; Meiyun Fang; Chenchen Wang; Li Han; Chenmeng Yang (Inflammation Research, 2020)

Methionine Sulfoxide Reductases Are Related to Arsenic Trioxide-Induced Oxidative Stress in Mouse Liver - Gaolong Zhong; Fang Wan; Hao Yan; Zhijun Ning; Congcong Wang; Ying Li; Jiaqiang Pan; Zhaoxin Tang; Zengming Yang; Riming Huang; Lianmei Hu (Biological Trace Element Research, 2020)

Chronic Copper Exposure Induces Hypospermatogenesis in Mice by Increasing Apoptosis Without Affecting Testosterone Secretion - Hanming Chen; Zhenlong Kang; Na Qiao; Gaoyang Liu; Kebin Huang; Xi Wang; Congying Pang; Qiwen Zeng; Zhaoxin Tang; Ying Li (Biological Trace Element Research, 2020)

Causes and Changes of Drought in China: Research Progress and Prospects - Qiang Zhang; Yubi Yao; Yaohui Li; Jianping Huang; Zhuguo Ma; Zhilan Wang; Suping Wang; Ying Wang; Yu Zhang (Journal of Meteorological Research, 2020)

Trace elements determination and health risk assessment of Tricholoma matsutake from Yunnan Province, China - Hong-xian Chen; Yun Chen; Songfei Li; Wei Zhang; Ying Zhang; Shan Gao; Na Li; Lei Tao; Ying Wang (Journal of Consumer Protection and Food Safety, 2020)

Elastic reverse-time migration in irregular tunnel environment based on polar coordinates - Ying-Ming Qu; Chang Zhou; Qurmet Worral; Zhen-Chun Li; Chang-Bo Wang; Jun-Zhi Sun (Applied Geophysics, 2020)

Baicalein attenuates caspase-independent cells death via inhibiting PARP-1 activation and AIF nuclear translocation in cerebral ischemia/reperfusion rats - Wei-Han Li; Ying-Lin Yang; Xiao Cheng; Man Liu; Shan-Shan Zhang; Yue-Hua Wang; Guan-Hua Du (Apoptosis, 2020)

Rainfall manipulation experiments as simulated by terrestrial biosphere models: Where do we stand? - Athanasios Paschalis; Simone Fatichi; Jakob Zscheischler; Philippe Ciais; Michael Bahn; Lena Boysen; Jinfeng Chang; Martin De Kauwe; Marc Estiarte; Daniel Goll; Paul J. Hanson; Anna B. Harper; et al. (Global Change Biology, 2020)
Changes in rainfall amounts and patterns have been observed and are expected to continue in the near future with potentially significant ecological and societal consequences. Modelling vegetation responses to changes in rainfall is thus crucial to project water and carbon cycles in the future. In this study, we present the results of a new model‐data intercomparison project, where we tested the ability of 10 terrestrial biosphere models to reproduce the observed sensitivity of ecosystem productivity to rainfall changes at 10 sites across the globe, in nine of which, rainfall exclusion and/or irrigation experiments had been performed. The key results are as follows: (a) Inter‐model variation is generally large and model agreement varies with timescales. In severely water‐limited sites, models only agree on the interannual variability of evapotranspiration and to a smaller extent on gross primary productivity. In more mesic sites, model agreement for both water and carbon fluxes is typically higher on fine (daily–monthly) timescales and reduces on longer (seasonal–annual) scales. (b) Models on average overestimate the relationship between ecosystem productivity and mean rainfall amounts across sites (in space) and have a low capacity in reproducing the temporal (interannual) sensitivity of vegetation productivity to annual rainfall at a given site, even though observation uncertainty is comparable to inter‐model variability. (c) Most models reproduced the sign of the observed patterns in productivity changes in rainfall manipulation experiments but had a low capacity in reproducing the observed magnitude of productivity changes. Models better reproduced the observed productivity responses due to rainfall exclusion than addition. (d) All models attribute ecosystem productivity changes to the intensity of vegetation stress and peak leaf area, whereas the impact of the change in growing season length is negligible. The relative contribution of the peak leaf area and vegetation stress intensity was highly variable among models.

Traits mediate drought effects on wood carbon fluxes - Zhenhong Hu; Han Y. H. Chen; Chao Yue; Xiao Ying Gong; Junjiong Shao; Guiyao Zhou; Jiawei Wang; Minhuang Wang; Jianyang Xia; Yongtao Li; Xuhui Zhou; Sean T. Michaletz (Global Change Biology, 2020)
CO 2 fluxes from wood decomposition represent an important source of carbon from forest ecosystems to the atmosphere, which are determined by both wood traits and climate influencing the metabolic rates of decomposers. Previous studies have quantified the effects of moisture and temperature on wood decomposition, but these effects were not separated from the potential influence of wood traits. Indeed, it is not well understood how traits and climate interact to influence wood CO 2 fluxes. Here, we examined the responses of CO 2 fluxes from dead wood with different traits (angiosperm and gymnosperm) to 0%, 35%, and 70% rainfall reduction across seasonal temperature gradients. Our results showed that drought significantly decreased wood CO 2 fluxes, but its effects varied with both taxonomical group and drought intensity. Drought‐induced reduction in wood CO 2 fluxes was larger in angiosperms than gymnosperms for the 35% rainfall reduction treatment, but there was no significant difference between these groups for the 70% reduction treatment. This is because wood nitrogen density and carbon quality were significantly higher in angiosperms than gymnosperms, yielding a higher moisture sensitivity of wood decomposition. These findings were demonstrated by a significant positive interaction effect between wood nitrogen and moisture on CO 2 fluxes in a structural equation model. Additionally, we ascertained that a constant temperature sensitivity of CO 2 fluxes was independent of wood traits and consistent with previous estimates for extracellular enzyme kinetics. Our results highlight the key role of wood traits in regulating drought responses of wood carbon fluxes. Given that both climate and forest management might extensively modify taxonomic compositions in the future, it is critical for carbon cycle models to account for such interactions between wood traits and climate in driving dynamics of wood decomposition.

Antioxidant coumarin and pyrone derivatives from the insect-associated fungus Aspergillus Versicolor - Tian-Xiao Li; Dan-Dan Meng; Ying Wang; Jin-Lu An; Jia-Feng Bai; Xue-Wei Jia; Chun-Ping Xu (Natural Product Research, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

Physiological and proteomic responses of mangrove plant Avicennia marina seedlings to simulated periodical inundation - Huan Li; Zan Li; Zhi-Jun Shen; Mei-Rong Luo; Yi-Ling Liu; Ming-Yue Wei; Wen-Hua Wang; Ying-Ying Qin; Chang-Hao Gao; Ke-Ke Li; Qian-Su Ding; Shan Zhang; et al. (Plant and Soil, 2020)

Role of T-type Calcium Channels in Generating Hyperexcitatory Behaviors during Emergence from Sevoflurane Anesthesia in Neonatal Rats - Feng-Yan Shen; Byung-Gun Lim; Wen Wen; Yu Zhang; Bo Cao; Yue-Guang Si; Li-Qing Ma; Meng Deng; Yang In Kim; Young-Beom Kim; Ying-Wei Wang (Neuroscience Bulletin, 2020)

Analysis of an improved workflow of endoscope reprocessing for bedside endoscopic diagnosis and treatment on COVID-19 patients - Qing Gu; Hua-fen Wang; Ying Fang; Ye Lu; Zhe Shen; Yan Wang; Xin Wu; Li Cen; Yi-shu Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Dynamic Alterations of Brain Injury, Functional Recovery, and Metabolites Profile after Cerebral Ischemia/Reperfusion in Rats Contributes to Potential Biomarkers - Xiao Cheng; Ying-Lin Yang; Wei-Han Li; Man Liu; Shan-Shan Zhang; Yue-Hua Wang; Guan-Hua Du (Journal of Molecular Neuroscience, 2020)

The nucleic acid positive rate and genotype distribution of human cytomegalovirus in human milk banks in China - Xiaoyu Min; Lin Wang; Aili Cui; Chunli Zhang; Dan Wang; Ying Liu; Zhenghong Li; Wenbo Xu (Archives of Virology, 2020)

Identification and genetic analysis of a totivirus isolated from the Culex tritaeniorhynchus in northern China - Fan Li; Jiang Du; Zhiqiang Wu; Weijia Zhang; Shihong Fu; Jingdong Song; Qianying Wang; Ying He; Wenwen Lei; Songtao Xu; Aiqiang Xu; Li Zhao; et al. (Archives of Microbiology, 2020)

SP94 Peptide-Functionalized PEG-PLGA Nanoparticle Loading with Cryptotanshinone for Targeting Therapy of Hepatocellular Carcinoma - Xiaoling Nie; Yuan Liu; Ming Li; Xuesong Yu; Wanwen Yuan; Sixi Huang; Di Ren; Ying Wang; Yan Wang (AAPS PharmSciTech, 2020)

Nanochemoprevention with therapeutic benefits: An updated review focused on epigallocatechin gallate delivery - Qiong-Qiong Yang; Xin-Lin Wei; Ya-Peng Fang; Ren-You Gan; Min Wang; Ying-Ying Ge; Dan Zhang; Li-Zeng Cheng; Harold Corke (Critical Reviews in Food Science and Nutrition, 2020)

Stripping Voltammetric Determination of Lead in Coastal Waters With a Functional Micro-Needle Electrode - Haitao Han; Dawei Pan; Ying Li; Jie Wang; Chenchen Wang (Frontiers in Marine Science, 2020)

A new triterpenoid saponin from Pulsatilla cernua predicted by NMR-based mosaic method - An-Dong Wang; Ying Bao; Xia Wang; Mei-Chen Li; Xu-Hong Ren; Jian-Yu Liu; Yong-Nan Xu (Natural Product Research, 2020)

The protective effects of Mogroside V and its metabolite 11-oxo-mogrol of intestinal microbiota against MK801-induced neuronal damages - Peijun Ju; Wenhua Ding; Jianhua Chen; Ying Cheng; Beibei Yang; Lanting Huang; Qiong Zhou; Cuizhen Zhu; Xiaobo Li; Mengyue Wang; Jinghong Chen (Psychopharmacology, 2020)

Optimization of the protoplast transient expression system for gene functional studies in strawberry (Fragaria vesca) - Yi-Jie Gou; Yu-Lian Li; Pin-Pin Bi; Dan-Juan Wang; Yang-Yang Ma; Yang Hu; Hou-Cheng Zhou; Ying-Qiang Wen; Jia-Yue Feng (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

The BIG gene controls size of shoot apical meristems in Arabidopsis thaliana - Wen Jie Zhang; Li Ming Zhai; Hai Xia Yu; Jing Peng; Shan Shan Wang; Xian Sheng Zhang; Ying Hua Su; Li Ping Tang (Plant Cell Reports, 2020)

Contribution of Baroreflex Afferent Pathway to NPY-Mediated Regulation of Blood Pressure in Rats - Yang Liu; Shu-Yang Zhao; Yan Feng; Jie Sun; Xiao-Long Lu; Qiu-Xin Yan; Ying Li; Zhuo Liu; Lu-Qi Wang; Xun Sun; Shijun Li; Guo-Fen Qiao; et al. (Neuroscience Bulletin, 2020)

Correction to: The Effects of 50 nm Unmodified Nano-ZnO on Lipid Metabolism and Semen Quality in Male Mice - Tao Kong; Shu-Hui Zhang; Cai Zhang; Ji-Liang Zhang; Fan Yang; Guo-Yong Wang; Zi-Jun Yang; Dong-Ying Bai; Yun-Yun Shi; Tian-Qi Liu; Hai-Long Li (Biological Trace Element Research, 2020)

The Effects of 50 nm Unmodified Nano-ZnO on Lipid Metabolism and Semen Quality in Male Mice - Tao Kong; Shu-Hui Zhang; Cai Zhang; Ji-Liang Zhang; Fan Yang; Guo-Yong Wang; Zi-Jun Yang; Dong-Ying Bai; Yun-Yun Shi; Tian-Qi Liu; Hai-Long Li (Biological Trace Element Research, 2020)

Seasonal and Sub-Seasonal Circulation Anomalies Associated with Persistent Rainy Days in 2018/2019 Winter in Shanghai, China - Wei Wang; Fei Xin; Xiao Pan; Ying Zhang; Tim Li (Journal of Meteorological Research, 2020)

Geochemistry, Sr-Nd-Pb Isotopic Compositions and Zircon U-Pb Geochronology of Neoproterozoic Mafic Dyke in the Douling Complex, South Qinling Belt, China - Tong Li; Liang Liu; Xiao-Ying Liao; Yong-Sheng Gai; Tuo Ma; Chao Wang (Journal of Earth Science, 2020)

Study of KIR gene expression at the mRNA level in specific donor-derived NK cells after allogeneic HSCT - Ying Li; Tian Wang; Xing Hu; Huanhuan Zhang; Luyao Chen; Xiaojing Bao; Jun He (Immunogenetics, 2020)

Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice - Ying Wang; Chao Yin; Zhidan Chen; Yang Li; Yan Zou; Xiang Wang; Yanpeng An; Feizhen Wu; Guoping Zhang; Chunjie Yang; Huiru Tang; Yunzeng Zou; et al. (Cell and Tissue Research, 2020)

Coix seed oil prolongs lifespan and enhances stress resistance in Caenorhabditis elegans - Xin-Yan Chen; De-Chun Liao; Ying-Ting Yu; Cong-Min Wei; Ling-Yan Xuan; Shan Li; Hong-Bing Wang (Biogerontology, 2020)

Characterization of a G9 group A rotavirus reassortant strain detected in Jinzhou, China, in 2018–2019 - Ying Lu; Hui Li; Weiwei Li; Xiaofang Wang; Xiaoli Tao; Lili Dou; Ying Dong; Nan Wu; Yong Gang Li (Archives of Virology, 2020)

Polymorphisms in arsenic (+ 3 oxidation state) methyltransferase (AS3MT) predict the occurrence of hyperleukocytosis and arsenic metabolism in APL patients treated with As2O3 - Wen-Sheng Liu; Xin-Yu Wang; Jing Lu; Ying-Mei Zhang; Xiang-Mei Ye; Jin-Mei Li; Qi-Lei Zhao; Zhi-Qiang Wu; Jin Zhou; Xin Hai (Archives of Toxicology, 2020)

Variation and evolution of C:N ratio among different organs enable plants to adapt to N‐limited environments - Jiahui Zhang; Nianpeng He; Congcong Liu; Li Xu; Zhi Chen; Ying Li; Ruomeng Wang; Guirui Yu; Wei Sun; Chunwang Xiao; Han Y. H. Chen; Peter B. Reich (Global Change Biology, 2020)
Carbon (C) and nitrogen (N) are the primary elements involved in the growth and development of plants. The C:N ratio is an indicator of nitrogen use efficiency (NUE) and an input parameter for some ecological and ecosystem models. However, knowledge remains limited about the convergent or divergent variation in the C:N ratios among different plant organs (e.g., leaf, branch, trunk, and root) and how evolution and environment affect the coefficient shifts. Using systematic measurements of the leaf–branch–trunk–root of 2,139 species from tropical to cold‐temperate forests, we comprehensively evaluated variation in C:N ratio in different organs in different taxa and forest types. The ratios showed convergence in the direction of change but divergence in the rate of change. Plants evolved toward lower C:N ratios in the leaf and branch, with N playing a more important role than C. The C:N ratio of plant organs (except for the leaf) was constrained by phylogeny, but not strongly. Both the change of C:N during evolution and its spatial variation (lower C:N ratio at midlatitudes) help develop the adaptive growth hypothesis. That is, plants with a higher C:N ratio promote NUE under strong N‐limited conditions to ensure survival priority, whereas plants with a lower C:N ratio under less N‐limited environments benefit growth priority. In nature, larger proportion of species with a high C:N ratio enabled communities to inhabit more N‐limited conditions. Our results provide new insights on the evolution and drivers of C:N ratio among different plant organs, as well as provide a quantitative basis to optimize land surface process models.

Contrasting the Pb (II) and Cd (II) tolerance of Enterobacter sp. via its cellular stress responses - Zhongquan Jiang; Liu Jiang; Lin Zhang; Mu Su; Da Tian; Tong Wang; Yalin Sun; Ying Nong; Shuijin Hu; Shimei Wang; Zhen Li (Environmental Microbiology, 2020)
Summary Successful application of microorganisms to heavy metal remediation depends on their resistance to toxic metals. This study contrasted the differences of tolerant mechanisms between Pb 2+ and Cd 2+ in Enterobacter sp. Microbial respiration and production of formic acid showed that Enterobacter sp. had a higher tolerant concentration of Pb (>1000 mg l −1 ) than Cd (about 200 mg l −1 ). Additionally, SEM confirmed that most of Pb and Cd nanoparticles (NPs) were adsorbed onto cell membrane. The Cd stress, even at low concentration (50 mg l −1 ), significantly enlarged the sizes of cells. The cellular size raised from 0.4 × 1.0 to 0.9 × 1.6 μm on average, inducing a platelet‐like shape. In contrast, Pb cations did not stimulate such enlargement even up to 1000 mg l −1 . Moreover, Cd NPs were adsorbed homogeneously by almost all the bacterial cells under TEM. However, only a few cells work as ‘hot spots’ on the sorption of Pb NPs. The heterogeneous sorption might result from a ‘self‐sacrifice’ mechanism, i.e., some cells at a special life stage contributed mostly to Pb sorption. This mechanism, together with the lower mobility of Pb cations, caused higher microbial tolerance and removal efficiency towards Pb 2+ . This study sheds evident contrasts of bacterial resistance to the two most common heavy metals.

New cytotoxic constituents in the water-soluble fraction from Momordicae Semen - Meng-Yue Wang; Zhi-Bin Zhan; Ying Xiong; Hao Zhang; Xiao-Bo Li (Natural Product Research, 2020)

Identification and characterization of a novel gene-encoded antioxidant peptide obtained from amphibian skin secretions - Ying Wang; Xiaoqing Cao; Zhe Fu; Siyuan Wang; Xiaojie Li; Naixin Liu; Zhuo Feng; Meifeng Yang; Jing Tang; Xinwang Yang (Natural Product Research, 2020)

An Improved Digital Volumetric Speckle Photography Technique with X-ray Microtomography and its Applications to Investigating Strain Localization in Red Sandstone - Lingtao Mao; Ying Zhu; Yuwei Wang; Yifan Liu; Liyun Li; Fu-pen Chiang (Rock Mechanics and Rock Engineering, 2020)

Bioaugmentation-assisted phytoremediation of manganese and cadmium co-contaminated soil by Polygonaceae plants (Polygonum hydropiper L. and Polygonum lapathifolium L.) and Enterobacter sp. FM-1 - Yi Li; Jiamin Lin; Yuanyuan Huang; Yawei Yao; Xueru Wang; Chengzhao Liu; Ying Liang; Kehui Liu; Fangming Yu (Plant and Soil, 2020)

Scorpion Venom Heat-Resistant Peptide is Neuroprotective against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway - Xu-Gang Wang; Dan-Dan Zhu; Na Li; Yue-Lin Huang; Ying-Zi Wang; Ting Zhang; Chen-Mei Wang; Bin Wang; Yan Peng; Bi-Ying Ge; Shao Li; Jie Zhao (Neuroscience Bulletin, 2020)

Primary age-related tauopathy in a Chinese cohort - Xin Wang; Lei Zhang; Hui Lu; Juan-li Wu; Hua-zheng Liang; Chong Liu; Qing-qing Tao; Zhi-ying Wu; Ke-qing Zhu (Journal of Zhejiang University-SCIENCE B, 2020)

Antioxidant Peptide AOP-P1 Derived from Odorous Frog Showed Protective Effects Against UVB-Induced Skin Damages - Saige Yin; Shanshan Li; Wenxin Bian; Meifeng Yang; Naixin Liu; Yan Hu; Xiaojie Li; Ying Wang; Ziliang Li; Jun Sun; Xinwang Yang (International Journal of Peptide Research and Therapeutics, 2020)

Identification of a novel D3 allele playing a role in nitrogen utilization - Ying Wang; Zhu Zhu; Ying Sun; Jile Ni; Jia Xie; Yangyang Li; Xiaobo Zhang; Xiaozhu Wen; Yuzhen Xiong; Xianchun Sang (Euphytica, 2020)

Association of Blood Lead Levels with the Risk of Depressive Symptoms in the Elderly Chinese Population: Baseline Data of a Cohort Study - Yong Fan; Jie Sheng; Chunmei Liang; Linsheng Yang; Kaiyong Liu; Qunan Wang; Dongmei Zhang; Ying Ma; Xiude Li; Shaoyu Xie; Hongjuan Cao; Sufang Wang; et al. (Biological Trace Element Research, 2020)

Infrared emission properties of a kind of natural carbonate: interpretation from mineralogical analysis - Ying Zhu; Yanzhang Li; Hongrui Ding; Anhuai Lu; Yan Li; Changqiu Wang (Physics and Chemistry of Minerals, 2020)

Separating and imaging diffractions in dip domain on the basis of slope analysis - Xue Kong; De-Ying Wang; Zhen-Chun Li; Rui-Xiang Zhang; Qiu-Yuan Hu (Applied Geophysics, 2020)

Fractional vegetation coverage response to climatic factors based on grey relational analysis during the 2000-2017 growing season in Sichuan Province, China - Peng Li; Zhengwei He; Dong He; Dongjian Xue; Ying Wang; Shisong Cao (International Journal of Remote Sensing, 2020)

Enhanced stability of a rumen-derived xylanase using SpyTag/SpyCatcher cyclization - Ye-Bo Zhou; Jia-Wen Cao; Xiao-Bao Sun; Huan Wang; De-Ying Gao; Yang-Nan Li; Kai-Yue Wu; Jia-Kun Wang; Guo-Ying Qian; Qian Wang (World Journal of Microbiology and Biotechnology, 2020)

Relative roles of formation and preservation on gold endowment along the Sanshandao gold belt in the Jiaodong gold province, China: importance for province- to district-scale gold exploration - Liang Zhang; David I. Groves; Li-Qiang Yang; Gong-Wen Wang; Xiang-Dong Liu; Da-Peng Li; Ying-Xin Song; Wei Shan; Si-Chen Sun; Zhao-Kun Wang (Mineralium Deposita, 2020)

Association of Corticotropin-Releasing Hormone Receptor-1 Gene Polymorphisms and Personality Traits with Violent Aggression in Male Adolescents - Li Liu; Yi Qiao; Yang Shao; Shun-ying Yu; Chen Zhang; Ran Zhang; Dong-xiang Wang; Min Zhao; Bin Xie (Journal of Molecular Neuroscience, 2020)

Multicenter feasibility study to assess external quality panels for molecular diagnostics for tuberculosis in China - Jian Du; Wei Shu; Yuhong Liu; Yufeng Wang; Ying Zhan; Kexin Yu; Jingtao Gao; Liang Li; Yu Pang (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Application of metagenomic next-generation sequencing for bronchoalveolar lavage diagnostics in critically ill patients - Ying Li; Bing Sun; Xiao Tang; Ya-lan Liu; Hang-yong He; Xu-yan Li; Rui Wang; Fei Guo; Zhao-hui Tong (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Breeding of cabbage lines resistant to both head splitting and fusarium wilt via an isolated microspore culture system and marker-assisted selection - Qiang Li; Yantong Shi; Ying Wang; Lujiang Liu; Xuesong Zhang; Xiaowen Chen; Lianzhong Zhang; Yanbin Su; Tianzhu Zhang (Euphytica, 2020)

Augmentation of danusertib’s anticancer activity against melanoma by blockage of autophagy - Yuan-Yuan Shang; Nan Yu; Li Xia; Ying-Yao Yu; Chun-mei Ma; Ya-Ning Jiao; Yun-feng Li; Yuan Wang; Jie Dang; Weichao Li (Drug Delivery and Translational Research, 2020)

Shared and specific functional connectivity alterations in unmedicated bipolar and major depressive disorders based on the triple-network model - Junjing Wang; Ying Wang; Xia Wu; Huiyuan Huang; Yanbin Jia; Shuming Zhong; Xiaoyan Wu; Lianping Zhao; Yuan He; Li Huang; Ruiwang Huang (Brain Imaging and Behavior, 2020)

The DI–DII linker of human parainfluenza virus type 3 fusion protein is critical for the virus - Ying Liu; Miaomiao Chi; Hongling Wen; Li Zhao; Yanyan Song; Na Liu; Lianli Chi; Zhiyu Wang (Virus Genes, 2020)

Development of Climate and Earth System Models in China: Past Achievements and New CMIP6 Results - Tianjun Zhou; Ziming Chen; Liwei Zou; Xiaolong Chen; Yongqiang Yu; Bin Wang; Qing Bao; Ying Bao; Jian Cao; Bian He; Shuai Hu; Lijuan Li; et al. (Journal of Meteorological Research, 2020)

Origins of Quasi-Biweekly and Intraseasonal Oscillations over the South China Sea and Bay of Bengal and Scale Selection of Unstable Equatorial and Off-Equatorial Modes - Ying Zhang; Tim Li; Jianyun Gao; Wei Wang (Journal of Meteorological Research, 2020)

cDNA-AFLP analysis of differentially expressed genes during microspore embryogenesis in non-heading Chinese cabbage - Ya Zhang; Su-yan Gao; Huan-huan Liu; Xi-lin Zhang; Ai-song Zeng; Jian-jun Wang; Xi-lin Hou; Ying Li (In Vitro Cellular & Developmental Biology - Plant, 2020)

v301, a new allele of BRITTLE CULM 12, and its regulation of the early senescence of the leaf blade in rice - Ji-le Ni; Xiao-zhu Wen; Cheng-bing Tang; Wei-jiang Tian; Wen-jing Yang; Jia Xie; Xiao-bo Zhang; Yang-yang Li; Yu-zhen Xiong; Ying Sun; Zhu Zhu; Ying Wang; et al. (Acta Physiologiae Plantarum, 2020)

Grazing simplifies soil micro‐food webs and decouples their relationships with ecosystem functions in grasslands - Bing Wang; Liji Wu; Dima Chen; Ying Wu; Shuijin Hu; Linghao Li; Yongfei Bai (Global Change Biology, 2020)
Livestock grazing often alters aboveground and belowground communities of grasslands and their mediated carbon (C) and nitrogen (N) cycling processes at the local scale. Yet, few have examined whether grazing‐induced changes in soil food webs and their ecosystem functions can be extrapolated to a regional scale. We investigated how large herbivore grazing affects soil micro‐food webs (microbes and nematodes) and ecosystem functions (soil C and N mineralization), using paired grazed and ungrazed plots at 10 locations across the Mongolian Plateau. Our results showed that grazing not only affected plant variables (e.g., biomass and C and N concentrations), but also altered soil substrates (e.g., C and N contents) and soil environment (e.g., soil pH and bulk density). Grazing had strong bottom‐up effects on soil micro‐food webs, leading to more pronounced decreases at higher trophic levels (nematodes) than at lower trophic levels (microbes). Structural equation modeling showed that changes in plant biomass and soil environment dominated grazing effects on microbes, while nematodes were mainly influenced by changes in plant biomass and soil C and N contents; the grazing effects, however, differed greatly among functional groups in the soil micro‐food webs. Grazing reduced soil C and N mineralization rates via changes in plant biomass, soil C and N contents, and soil environment across grasslands on the Mongolian Plateau. Spearman's rank correlation analysis also showed that grazing reduced the correlations between functional groups in soil micro‐food webs and then weakened the correlation between soil micro‐food webs and soil C and N mineralization. These results suggest that changes in soil micro‐food webs resulting from livestock grazing are poor predictors of soil C and N processes at regional scale, and that the relationships between soil food webs and ecosystem functions depend on spatial scales and land‐use changes.

Overexpression of HbMBF1a, encoding multiprotein bridging factor 1 from the halophyte Hordeum brevisubulatum, confers salinity tolerance and ABA insensitivity to transgenic Arabidopsis thaliana - Lili Zhang; Yunxiao Wang; Qike Zhang; Ying Jiang; Haiwen Zhang; Ruifen Li (Plant Molecular Biology, 2020)
Key message HbMBF1a was isolated and characterized in H. brevisubulatum , and overexpressed HbMBF1a could enhance the salt tolerance and ABA insensitivity in Arabidopsis thaliana . The transcript levels of stress-responsive genes were significantly increased in the transgenic lines under salt and ABA conditions. Abstract Salinity is an abiotic stress that considerably affects plant growth, yield, and distribution. Hordeum brevisubulatum is a halophyte that evolved to become highly tolerant to salinity. Multiprotein bridging factor 1 (MBF1) is a transcriptional coactivator and an important regulator of stress tolerance. In this study, we isolated and characterized HbMBF1a based on the transcriptome data of H. brevisubulatum grown under saline conditions. We overexpressed HbMBF1a in Arabidopsis thaliana and compared the phenotypes of the transgenic lines and the wild-type in response to stresses. The results indicated that HbMBF1a expression was induced by salt and ABA treatments during the middle and late stages. The overexpression of HbMBF1a in A. thaliana resulted in enhanced salt tolerance and ABA insensitivity. More specifically, the enhanced salt tolerance manifested as the increased seed germination and seedling growth and development. Similarly, under ABA treatments, the cotyledon greening rate and seedling root length were higher in the HbMBF1a -overexpressing lines, suggesting the transgenic plants were better adapted to high exogenous ABA levels. Furthermore, the transcript levels of stress-responsive genes were significantly increased in the transgenic lines under salt and ABA conditions. Thus, HbMBF1a is a positive regulator of salt and ABA responses, and the corresponding gene may be useful for producing transgenic plants that are salt tolerant and/or ABA insensitive, with few adverse effects. This study involved a comprehensive analysis of HbMBF1a . The results may provide the basis and insight for the application of MBF1 family genes for developing stress-tolerant crops.

Growth and physiological alterations related to root-specific gene function of LrERF061-OE in Glycyrrhiza uralensis Fisch. hairy root clones under cadmium stress - Aysha Arif Chahel; Zubaida Yousaf; Shaohua Zeng; Yuping Li; Wang Ying (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)