Decadal shift of the influence of Arctic Oscillation on dust weather frequency in spring over the Middle East during 1974–2019 - Yijie Sun; Rui Mao; Dao‐Yi Gong; Ying Li; Seong‐Joong Kim; Xiao‐Xiao Zhang; Xuezhen Zhang; Mehdi Hamidi (International Journal of Climatology, 2022)
Dust weather has an impact on human health and climate change in the Middle East. In this study, we examined the influence of the Arctic Oscillation (AO) on spring dust weather frequency over the Middle East at an interannual timescale during 1974–2019. The results show that there was an interdecadal shift of the influence of AO on dust weather frequency in the Middle East, with a correlation coefficient between the AO index and dust weather frequency changing from −0.52 during 1974–1994 period (P1) to 0.49 during 1995–2013 period (P2). During P1, negative correlations between AO index and dust weather frequency were found over the northern Arabian Peninsula, and during P2, positive ones were mostly over the central and southwestern Arabian Peninsula. In the lower and middle troposphere, negative geopotential height anomalies are associated with the negative phase of the AO over South Europe during P1, whereas negative geopotential height anomalies are associated with the positive phase of the AO over Northeast Africa during P2. The negative height anomalies resulted in the occurrence of more low‐pressure systems and, thus, dust weather in the Middle East. It is found that the interdecadal shift of the influence of the AO on dust weather was related to an AO‐related northward displacement of wave train propagation during P2. Specifically, during P1 period, the northern branch of AO‐related wave train dominated over the middle latitudes of the North Atlantic across South Europe to the Arabian Peninsula, which resulted in the negative height anomaly over South Europe in the lower and middle troposphere. However, during P2 period, the AO‐related wave train propagation moved northward, and then, the southern branch of the AO‐related wave train dominated over the low latitudes of the North Atlantic across northern Africa to the Arabian Peninsula, which played an important role in the formation of the negative height anomalies over Northeast Africa.

Genetic Stock Identification and Adaptability of Hatchery-Reared Black Rockfish, Sebastes schlegelii, Released Into the North Yellow Sea waters - Qi Liu; Ziwei Wang; Weiyuan Li; Qi Zhang; Binwei Liu; Meiyuan Li; Ying Liu; Tao Tian; Hongwei Yan (Frontiers in Marine Science, 2022)
Successful stock enhancement refers to the maintenance of economic profit, whilst minimizing negative genetic and ecological effects. As hatchery environments differ from natural habitats, post-release identification of hatchery-reared juveniles, and estimation of their adaptability are essential steps in conducting responsible stock enhancement. The black rockfish is an important fishery species in Japan, South Korea and China. Overfishing has dramatically decreased natural resources and a stock enhancement program was first initiated in the Liaodong peninsula in 2019. We traced this program and used nine microsatellite markers to identify 279 individuals as being hatchery-reared, out of 710 captured fish, with a resource contribution rate of 39.30%. These results indicated that stock enhancement of this species is likely to maintain a positive economic performance. To understand the potential genetic impacts on the local wild population, the genetic patterns of S. schlegelii stocks (wild controls from 2017, wild controls from 2018, female broodstock from 2019, recaptured hatchery-reared fish from 2019 and recaptured non-hatchery-reared fish from 2019 stocks) from the same habitat were evaluated before and after artificial stocking. We found that the S. schlegelii population was able to maintain high genetic diversity and showed weak genetic differentiation, but potential genetic introgression derived from stock enhancement should be concerned. The hatchery-reared individuals showed good adaptability, as shown by feeding condition and growth status. There was no obvious morphology difference between hatchery-reared fish and their wild counterparts, but hatchery-reared fish seemed to be bigger in size (significantly higher in MDB and BW), had a larger head (significantly larger in PRL/HL and ID/HL) and smaller paired fins (significantly smaller PCFL/BL), when compared with wild individuals across all investigation months. Our results provided insights into management of black rockfish enhancement in the future.

Residue changes of five pesticides during the production and storage of rice flour - Jinmiao Duan; Qingchao Gao; Lu Shi; Yahui Li; Zhiyong Zhang; Ying Liang (Food Additives & Contaminants: Part A, 2022)

Mungbean VrCOL1 regulates flowering time under short-day conditions in Arabidopsis - Qianqian Zhang; Jing Dong; Zhanqi Wang; Ying Wang; Chunmei Cai; Hong Zhu; Shuai Li (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Associations of CXCL12 polymorphisms with clinicopathological features in breast cancer: a case-control study - Shuai Lin; Yi Zheng; Meng Wang; Linghui Zhou; Yuyao Zhu; Yujiao Deng; Ying Wu; Dai Zhang; Na Li; Huafeng Kang; Zhijun Dai (Molecular Biology Reports, 2022)
Background Previous studies suggested that CXCL12 was involved in the development, metastasis, and invasion of breast cancer, and genetic variants were associated with the diagnosis and prognosis of patients with breast cancer. The present study was aimed to assess the relationships between CXCL12 polymorphisms (rs1801157, rs2297630, and rs2839693) and susceptibility and clinicopathological features of breast cancer. Methods A case-control study was conducted in 434 breast cancer patients and 450 health controls. Student t -test and chi-square test were used to analyze the differences of age distribution and genotype frequencies between the two groups. Correlations between polymorphisms and clinical parameters were also assessed by chi-square test. The potential effects of the three polymorphisms on CXCL12 were investigated by the public database. Results A statistical association was found between CXCL12 rs1801157 polymorphism and breast cancer risk, possibility of metastasis, and estrogen receptor status. Patients with rs2839693 C/T or C/T-T/T genotypes were more likely to be progesterone receptor-negative. However, no associations of rs2297630 polymorphism with breast cancer risk or any clinicopathological characteristics were observed. In addition, rs2297630 affected the splicing quantitative trait loci of CXCL12 in the subcutaneous fat, rs2839693 polymorphism affected the splicing quantitative trait loci of CXCL12 in the human breast mammary tissues. Conclusions Those results indicated that CXCL12 polymorphisms might be potential diagnostic indicators, and more investigation is needed in the future.

Bioinformatics Analysis of the MicroRNA-Metabolic Gene Regulatory Network in Neuropathic Pain and Prediction of Corresponding Potential Therapeutics - Huai-Gen Zhang; Li Liu; Zhi-Ping Song; Da-Ying Zhang (Journal of Molecular Neuroscience, 2022)

Optimizing nitrogen fertilizer application under reduced irrigation strategies for winter wheat of the north China plain - Ying Liu; Meikun Han; Xiaonan Zhou; Wei Li; Chenghang Du; Yitao Zhang; Yinghua Zhang; Zhencai Sun; Zhimin Wang (Irrigation Science, 2022)

QTL mapping integrated with BSA-Seq analysis identifies a novel gene conferring resistance to brown planthopper from common wild rice (Oryza rufipogon Griff.) - Xuan Wang; Yue Han; Yue-xiong Zhang; Biao Deng; Bi-qiu Wu; Xin-ying Guo; Yu-fen Qin; Yao-yu Fang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Euphytica, 2022)

Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis - Zhuo-Zhi Liang; Yi-Xin Zhang; Rui-Mei Zhu; Yue-Lin Li; Hong-Mei Jiang; Ruo-Bi Li; Qian-Xin Chen; Qing Wang; Lu-Ying Tang; Ze-Fang Ren (Environmental Science and Pollution Research, 2022)

Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components - Tingting Lin; Jiaqi Tao; Ying Chen; Yitong Zhang; Fenglan Li; Yutong Zhang; Xueqing Han; Zihui Zhao; Guiyan Liu; Hui Li (Biological Trace Element Research, 2022)

Vibrational and structural insight into silicate minerals by mid-infrared absorption and emission spectroscopies - Ying Zhu; Yanzhang Li; Hongrui Ding; Anhuai Lu; Yan Li; Xiang Ji; Yuanlong Zhang; Changqiu Wang (Physics and Chemistry of Minerals, 2022)

Estimation of permafrost thermal behavior using Fourier series model - Yan-yu Zhang; Shu-ying Zang; Lin Zhao; Da-long Ma; Yue Lin; Hao Li (Journal of Mountain Science, 2022)

Performance evaluation of fixed-station sampling design for a fishery-independent survey with multiple objectives - Jing Wang; Binduo Xu; Ying Xue; Chongliang Zhang; Mingkun Li; Yiping Ren (Acta Oceanologica Sinica, 2022)

Risk and protection strategies of Amolops wuyiensis intestine against gastrointestinal nematode ( Cosmocercoides wuyiensis n. sp.) infection - Yilin Shu; Yunyun Xie; Shikun Li; Liming Cai; Ying Liu; Yalin Feng; Jun He; Huijuan Zhang; Menglong Ran; Qina Jia; Hailong Wu; Linming Lu (Environmental Microbiology, 2022)
Summary Anuran amphibians are susceptible to infection by intestinal nematodes, but the damage and response mechanisms that occur in their intestines after infection are only partially understood. In this study, the intestinal disruption and response mechanisms in Amolops wuyiensis frogs infected with Cosmocercoides wuyiensis n. sp. were revealed through analysis of the intestinal histopathology, digestive enzyme activity, transcriptome and intestinal microbiota. Tissue section analysis showed histological damage and inflammation in the infected intestine, and the digestive enzyme activity indicated a decrease in digestion and absorption of some nutrients. We found that infection led to differences in the intestinal microbiota composition, including lower diversity and symbiotic relationships. The greater relative abundance of the genera Burkholderia and Rhodococcus may enhance intestinal immunity to resist pathogenic infections. A comparison of the transcriptomes of infected and uninfected intestines revealed 1055 differentially expressed genes. GO enrichment and KEGG pathways analyses suggested that the guts of infected C . wuyiensis n. sp. show enhanced complement activation, cell adhesion molecule function, NOD‐like receptor signalling pathway activity and other innate immunity responses. Among the adaptive immune responses, the intestinal immune network for IgA production was significantly enriched, and the expression of IL‐17D and transforming growth factor beta‐1 genes were upregulated in the infected intestine. These results imply that C . wuyiens is n. sp. infection of A . wuyiensis intestine may trigger innate and adaptive immune responses, which reduce the post‐infection burden. Furthermore, the intestine of A . wuyiensis may also respond to C . wuyiensis n. sp. infection by increasing metallocarboxypeptidase activity and accelerating smooth muscle contraction.

Mesoporous Silica Carrier-Based Composites for Taste-Masking of Bitter Drug: Fabrication and Palatability Evaluation - Weifeng Zhang; Guoxiang Li; Chaoqiang Xiao; Xin Chang; Ying Sun; Weiping Fan; Bing Tian; Di Gao; Yao Xiao; Xueping Wu; Shuwang He; Guangxi Zhai (AAPS PharmSciTech, 2022)

Functional Mechanism of Antimicrobial Peptide Bomidin and Its Safety for Macrobrachium rosenbergii - Miao Zhang; Youli Yu; Lele Lian; Wanjun Li; Jianluan Ren; Ying Liang; Feng Xue; Fang Tang; Xiaohua Zhu; Jianqun Ling; Jianjun Dai (Probiotics and Antimicrobial Proteins, 2022)

Genome-wide identification of HD-ZIP transcription factors in maize and their regulatory roles in promoting drought tolerance - Xiao Qiu; GuoRui Wang; Salah Fatouh Abou-Elwafa; Jiaxu Fu; Zhixue Liu; PengYu Zhang; Xiaowen Xie; Lixia Ku; Ying Ma; XiaoKang Guan; Li Wei (Physiology and Molecular Biology of Plants, 2022)

Plant-derived lignans as potential antiviral agents: a systematic review - Xin-Ya Xu; Dong-Ying Wang; Yi-Ping Li; Stephen T. Deyrup; Hong-Jie Zhang (Phytochemistry Reviews, 2022)

Synthesis and evaluation of ursolic acid-based 1,2,4-triazolo[1,5-a]pyrimidines derivatives as anti-inflammatory agents - Tian-Yi Zhang; Chun-Shi Li; Ping Li; Xue-Qian Bai; Shu-Ying Guo; Ying Jin; Sheng-Jun Piao (Molecular Diversity, 2022)

Structural Characterization and Immunoenhancing Effects of a Polysaccharide from the Soft Coral Lobophytum sarcophytoides - Xueqin Cao; Qian Zhang; Yanglu Zhu; Siju Li; Ying Cai; Pei Li; Deliang Liu; Yun Leng; Simin Ye; Zengmei Xu; Hao Li; Baochun Shen; et al. (Marine Biotechnology, 2022)

GWAS Reveal Novel Sex-Related Markers and Candidate Genes in Sea Urchin Mesocentrotus nudus - Quanchao Wang; Ying Liu; Yanxia Wang; Shaoyu Jiang; Chuanxin Zhang; Baoquan Li (Marine Biotechnology, 2022)

The Prevalence and Trends of Obesity in Chinese Preschool Children from 1996 to 2019: A Meta-analysis - Liu Zhang; Hongjuan Li; Zhaohua Zhang; Ying Luo (Journal of Science in Sport and Exercise, 2022)

Production of dimethyl sulfide and acrylic acid from dissolved dimethylsulfoniopropionate during the growth of Prorocentrum minimum - Pei-Feng Li; Pei-Pei Gao; Chun-Ying Liu; Hong-Hai Zhang; Gui-Peng Yang (Journal of Applied Phycology, 2022)

The association between short-term ambient air pollution and acne vulgaris outpatient visits: a hospital-based time-series analysis in Xi’an - Xiang Li; Yi Cao; Shu-Jie An; Ying Xiang; He-Xiang Huang; Bin Xu; Yao Zhang; Ya-Fei Li; Yuan-Gang Lu; Tong-Jian Cai (Environmental Science and Pollution Research, 2022)

Differential expression of long non-coding RNAs in the hippocampus of mice exposed to PM2.5 in Dalian, China - Jie Li; Longying Zhang; Jiaqi Wang; Ruxue Jia; Xiao Zhang; Xiaojing Li; Ying Fu; Laiyu Song (Environmental Science and Pollution Research, 2022)

Effect of additives on the remediation of arsenic and chromium co-contaminated soil by an electrokinetic-permeable reactive barrier - Chunzi Ma; Jiangpeng Li; Wei Xia; Ying Ding; Liting Zhang; Yunfeng Xu (Environmental Science and Pollution Research, 2022)

Transcriptome Analysis Reveals Molecular Mechanisms Underlying Methyl Jasmonate-mediated Biosynthesis of Protopanaxadiol-type Saponins in Panax notoginseng Leaves - Ying Li; Yuan Lin; Bing Jia; Geng Chen; Huineng Shi; Rui Xu; Xuejiao Li; Junrong Tang; Qingyan Tang; Guanghui Zhang; Jianli Yang; Wei Fan; et al. (Journal of Plant Biology, 2022)

Responses and feedback of litter properties and soil mesofauna to herbaceous plants expansion into the alpine tundra on Changbai Mountain, China - Ying-jie Zhang; Ying-hua Jin; Jia-wei Xu; Hong-shi He; Yan Tao; Zhi-peng Yang; Jing Zhao; Yin-xia Diao; Chen-hui Sun; Mai-He Li (Journal of Mountain Science, 2022)

Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout - Ya-Wei Geng; Zhen Zhang; Han Jin; Jun-Long Da; Kai Zhang; Jian-Qun Wang; Yu-Yao Guo; Bin Zhang; Ying Li (Genes & Genomics, 2022)

Characterizing the Semi-Volatile Organic Compounds in Runoff from Roads and Other Impervious Surfaces in a Suburban Area of Beijing - Liang Zhang; Haiyan Li; Youshu Wang; Zhichao Yang; Ziyang Zhang; Fei Liu; Linlin Tong; Ying Wang; Yongwei Gong; Hua Yang (Archives of Environmental Contamination and Toxicology, 2022)

Responses of Rhodotorula mucilaginosa under Pb( II ) stress: carotenoid production and budding - Zhijun Wang; Ying Zhang; Liu Jiang; Jingjing Qiu; Yanan Gao; Tingting Gu; Zhen Li (Environmental Microbiology, 2022)
Summary Rhodotorula mucilaginosa resists heavy metal (HM) stress because of its abundant extracellular polymeric substances and functional vesicles. In this study, we provided new insights into its survival strategies at both biochemical and genetic levels. After lead exposure, carotenoid biosynthesis was initiated within 24 h incubation and then increased to the maximum after 96 h of incubation. Raman analysis confirmed that carotenoids (primarily β‐carotene) were the major identifiable chemical substances on the cell surface. Moreover, the increased carotenoid production was accompanied by a rising budding rate, ~40% higher than that in the cultures without Pb. During the 96 h of incubation, the driving force for Pb accumulation was assigned to this elevated budding rate. After 96 h, biosorption was primarily attributed to the enhanced antioxidant ability of the single cells during carotenoid production. Furthermore, the yeast budding cells demonstrated an evidently heterogeneous biosorption of Pb, i.e., the rejuvenated daughters had a relatively lower Pb level than the mother cells. This resulted in the protection of the buds from Pb stress. After investigating phosphorus uptake and the RNA sequencing data, we finally confirmed two tightly correlated pathways that resist HM stress, i.e., biochemical (carotenoid production) and reproductive (healthy buds) pathways.

New paraconic acids from the endophytic fungus Xylariaceae sp. J4 - Chao Yuan; Xue-Chun Shu; Lin Fan; Ying-Bo Zhang; Ling-Liang Guan; Fu-Lai Yu; Xiao-Lu Chen; Gang Li (Natural Product Research, 2022)

Regulation of β1-integrin in autophagy and apoptosis of gastric epithelial cells infected with Helicobacter pylori - Boqing Li; Qianyu Rong; Yunqiu Du; Ruiqing Zhang; Jing Li; Xiaohan Tong; Li Geng; Ying Zhang (World Journal of Microbiology and Biotechnology, 2022)

Study on Gas Transport Performance in Perforated Gas Diffusion Layer by Lattice Boltzmann Method - Ziheng Jiang; Guogang Yang; Qiuwan Shen; Shian Li; Jiadong Liao; Hao Wang; Zhonghua Sheng; Ruomeng Ying; Zheng Li; Guoling Zhang; Hongpeng Zhang (Transport in Porous Media, 2022)

Cloning and functional analysis of soluble acid invertase 2 gene (SbSAI-2) in sorghum - Wuyuntanmanda; Fen-Xia Han; Bao-Qing Dun; Ji Zhang; Zhi Wang; Yi Sui; Li Zhu; Gui-Ying Li (Planta, 2022)

Neutrophil Extracellular Traps Exacerbate Ischemic Brain Damage - Congqin Li; Ying Xing; Yuqian Zhang; Yan Hua; Jian Hu; Yulong Bai (Molecular Neurobiology, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

A Novel De Novo TUBB3 Variant Causing Developmental Delay, Epilepsy and Mild Ophthalmological Symptoms in a Chinese Child - Jiao Xue; Zhenfeng Song; Shuyin Ma; Zhi Yi; Chengqing Yang; Fei Li; Kaixuan Liu; Ying Zhang (Journal of Molecular Neuroscience, 2022)

Long noncoding RNA XIST modulates microRNA-135/CREB1 axis to influence osteogenic differentiation of osteoblast-like cells in mice with tibial fracture healing - Ying Zhang; Qiang Yuan; Qiushi Wei; Peifeng Li; Zhikun Zhuang; Jitian Li; Youwen Liu; Leilei Zhang; Zhinan Hong; Wei He; Haibin Wang; Wuyin Li (Human Cell, 2022)

Piezo1 mediates endothelial atherogenic inflammatory responses via regulation of YAP/TAZ activation - Ying Yang; Danyang Wang; Chunxiao Zhang; Wenqing Yang; Chao Li; Zichen Gao; Ke Pei; Yunlun Li (Human Cell, 2022)

A Sensitivity Analysis of the Anisotropy of Hydraulic Conductivity to the Seepage, Deformation and Stability of Anti-dipping Layered Rock Slopes: A Case Study of the Pulang Area in Southwestern China - Guangkeng Zhang; Guangyin Lu; Chengzhi Xia; Lianrong Wu; Zongming Xu; Ying Bai; Jialu Li (Geotechnical and Geological Engineering, 2022)
In this paper, in order to study the influence of anisotropy ratios and anisotropy directions on the seepage, deformations and stability of the anti-dipping layered rock slopes, Geo-studio software was used in this study for the numerical analysis of carbonaceous slate slopes on the unsaturated seepage, fluid–solid coupling, and stability theory in Pulang area. The results showed that the maximum surface water content of the layered rock slopes gradually decreased with increases of the water conductivity anisotropy ratio and decreases in the anisotropy angle of the anti-dipping layered rock slopes. In addition, the rainfall infiltration depths in the middle sections of the slopes were observed to be the most affected by the anisotropy ratio and dip angles of the rock formations. Meanwhile, the bottom sections of slopes were the least affected by the anisotropy ratio and the dip angles of the rock formations. In regard to the anti-dipping rock slopes, it was found that the anisotropy ratio and rock layer dip angles should be considered in the deformation and stability analyses. When the seepage of an anti-dipping layered slope was considered to be isotropic, the safety factors often were overestimated. As the anisotropy ratio decreases and the anti-dipping angles of the layered planes increases, the safety factors of the slopes will gradually decrease. This study provided a feasible scheme for evaluating the seepage, deformations and stability of the anti-dipping layered rock slopes in southwest China’s Pulang area.

N-acetylcysteine alleviates pulmonary inflammatory response during benzo[a]pyrene-evoked acute lung injury - Hui Zhao; Lin Fu; Hui-Xian Xiang; Ying Xiang; Meng-Die Li; Bian-Bian Lv; Zhu-Xia Tan; Lan Gao; Cheng Zhang; De-Xiang Xu (Environmental Science and Pollution Research, 2022)

Mongoliitalea daihaiensis sp. nov., isolated from Daihai Lake in Inner Mongolia - Kai Jiang; Bo Yuan; Chun Ling Cao; Chen Ying Zhang; Ruo Xuan Li; Yan An (Archives of Microbiology, 2022)

Enhanced photosynthetic nitrogen use efficiency and increased nitrogen allocation to photosynthetic machinery under cotton domestication - Zhang-Ying Lei; Heng Wang; Ian J. Wright; Xin-Guang Zhu; Ülo Niinemets; Zi-Liang Li; Dong-Sheng Sun; Ning Dong; Wang-Feng Zhang; Zhong-Li Zhou; Fang Liu; Ya-Li Zhang (Photosynthesis Research, 2021)

Simvastatin Blocks Reinstatement of Cocaine-induced Conditioned Place Preference in Male Mice with Brain Lipidome Remodeling - Wei Xu; Yuman He; Jiamei Zhang; Hongchun Li; Xuemei Wan; Menglu Li; Yonghai Wang; Rui Xu; Haoluo Zhang; Yanping Dai; Haxiaoyu Liu; Linhong Jiang; et al. (Neuroscience Bulletin, 2021)

Expression of Slit and Robo during remodeling of corticospinal tract in cervical spinal cord in middle cerebral artery occlusion rats - Zhenhao Ying; Junxuan Wu; Wenjun Jiang; Guoli Zhang; Weiming Zhu; Xin Li; Xueyun Pang; Wei Liu (Molecular Biology Reports, 2021)

Hydrogen Sulfide Maintains Good Nutrition and Delays Postharvest Senescence in Postharvest Tomato Fruits by Regulating Antioxidative Metabolism - Ting-Ying Zhong; Gai-Fang Yao; Sha-Sha Wang; Ting-Ting Li; Ke-Ke Sun; Jun Tang; Zhong-Qin Huang; Feng Yang; Yan-Hong Li; Xiao-Yan Chen; Lan-Ying Hu; Hua Zhang; et al. (Journal of Plant Growth Regulation, 2021)

Overexpression of the PLK4 Gene as a Novel Strategy for the Treatment of Autosomal Recessive Microcephaly by Improving Centrosomal Dysfunction - Ya-Song Xu; Zhi-Ying Su; Li Sun; Xiao-Mei Yang; Shi-Yu Sun; Xiao-Fei Ji; Yi-Zhen Ji; Su-Qing Zhang; Jie Tian; Qi-Chang Wu (Journal of Molecular Neuroscience, 2021)

Putative role of uncoupling proteins in mitochondria-nucleus communications and DNA damage response - Yahan Niu; Chang Liu; Rui Zhang; Ying Jing; Donghai Li (Journal of Biosciences, 2021)

Allelopathically inhibitory effects of 5,4′-dihydroxyflavone on the growth, antioxidant system and photosynthesis of the bloom-forming cyanobacterium Microcystis aeruginosa - Jie Wang; Ying Shi; Meng Zhang; Yanhui Li; Qi Liu; Shulian Xie (Journal of Applied Phycology, 2021)

Atrial Natriuretic Peptide (ANP) Regulates the Biological Activity of EGF/EGFR System in Adult Retinal Pigment Epithelial Cell - Jingyan Li; Yong Wang; Juan Chen; Siyuan Zhang; Ying Zeng (International Journal of Peptide Research and Therapeutics, 2021)

Distinct phylogeographic structures and evolutionary histories of wild medicinal Salvia miltiorrhiza Bunge plant populations in the mountains of Central China - Xiaoguo Wang; Tao Ma; Ying Yun; Yan Li; Jing Zhang; Hongyan Liang; Xitian Yang (Genetic Resources and Crop Evolution, 2021)

Effect of protopine exposure on the physiology and gene expression in the bloom-forming cyanobacterium Microcystis aeruginosa - Jie Wang; Lingjia Kong; Yanhui Li; Jiazhen Zhang; Ying Shi; Shulian Xie; Bo Li (Environmental Science and Pollution Research, 2021)

The health risk assessment of Heavy Metals (HMs) in road dust based on Monte Carlo simulation and bio-toxicity: a case study in Zhengzhou, China - Huina Zhu; Xiaolong Liu; Chunhong Xu; Liangbo Zhang; Hanyu Chen; Fan Shi; Ying Li; Yongzhi Liu; Baozhong Zhang (Environmental Geochemistry and Health, 2021)

Astaxanthin Ameliorates Blood Pressure in Salt-Induced Prehypertensive Rats Through ROS/MAPK/NF-κB Pathways in the Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Yan Zhang; Chen-Long Wang; Yi-Ming Lei; Jia-Yue Yu; Dong-Miao Zong; Kai-Li Liu; Dong-Dong Zhang; Ying Li; Hua Tian; Nian-Ping Zhang; et al. (Cardiovascular Toxicology, 2021)

Mineralogical characteristics and sedimentary envrionment significance of water-insoluble minerals in potash deposits of Vientiane Basin of Laos - Tang Qi-liang; Zhang Xi-ying; Miao Wei-liang; Ma Hai-zhou; Li Yong-shou; Li Wen-xia; Yuan Xiao-long (Carbonates and Evaporites, 2021)

Genome editing of Corynebacterium glutamicum mediated with Cpf1 plus Ku/LigD - Fa-Yu Yang; Nan Wei; Zhi-Hao Zhang; Mi Wang; Ying-Chun Liu; Li-Fang Zhang; Feng Gu (Biotechnology Letters, 2021)

Long-term changes of water acidity in an intact forested watershed in south China - Xiao-dong Liu; Ying-jie Feng; Qi-feng Mo; Guo-wei Chu; Yue-lin Li; Qian-mei Zhang; Wei-qiang Zhang; Xian-hua Gan; Qing Zhou (Journal of Mountain Science, 2021)

Mitochondrial Genome of Episesarma lafondii (Brachyura: Sesarmidae) and Comparison with Other Sesarmid Crabs - Ying Zhang; Yan Gao; Li Gong; Xinting Lu; Lihua Jiang; Bingjian Liu; Liqin Liu; Zhenming Lü; Pengfei Li (Journal of Ocean University of China, 2021)

Evaluation of four artificial diets on demography parameters of Neoseiulus barkeri - Ya-Ying Li; Jin-Ge Yuan; Ming-Xiu Liu; Zi-Hui Zhang; Hai-Wei Zhou; Huai Liu (BioControl, 2021)

The Common Occurrence of Theileria ovis in Tibetan Sheep and the First Report of Theileria sinensis in Yaks from Southern Qinghai, China - Ye Wang; Bo Wang; Qingxun Zhang; Ying Li; Ziwen Yang; Shuyi Han; Guohui Yuan; Shuangling Wang; Hongxuan He (Acta Parasitologica, 2021)

Immersion immunization of common carp with bacterial ghost‐based DNA vaccine inducing prophylactic protective immunity against spring viraemia of carp virus - Yu‐Ying Zheng; Chen Zhang; Yang Li; Peng‐Qi Zhang; Guo Chen; Gao‐Xue Wang; Bin Zhu (Journal of Fish Diseases, 2021)
The interactive applications of immunization route, vaccine type and delivery vectors are emerging as a key area of research within the field of mass immunization in fishery production. In an effort to improve DNA vaccine's immune efficiency in large‐scale immunization, a promising bacterial ghost‐loaded DNA vaccine was constructed based on Escherichia coli DH5α. In common carp was investigated the immune response to immersion immunization via related indicator analysis, and the challenge test of spring viraemia of carp virus (SVCV) was carried out. The result indicated that BG‐loaded DNA vaccine induced higher serum antibody level than naked pEG‐G. Simultaneously, the immunophysiological indicators and genes change at the more advanced levels in the BG/pEG‐G immune group. At the treatment concentration of 20 mg/L of the BG/pEG‐G group, IgM and IgZ expressions in vivo were markedly increased by 21.62 times and 6.91 times, respectively, and the relative percentage survival reached the peak of 59.57%. This study paves the way for future aquatic animal vaccine research, which aimed to develop the highly effective immersion vaccine system by delivery vectors, with the ultimate aim to prevent and restrict SVCV in actual production.

Possible connection between declining Barents Sea ice and interdecadal increasing northeast China precipitation in May - Xingxing Li; Jianqi Sun; Mengqi Zhang; Ying Zhang; Jiehua Ma (International Journal of Climatology, 2021)
Northeast China is a major agricultural production base in East Asia, and spring is the agricultural ploughing season throughout the region. The precipitation in spring is therefore significant to agricultural activity and production in the region. In this study, the interdecadal variation in spring precipitation across northeast China is investigated. In the past four decades, there has been a significant increase in spring precipitation in northeast China, and the increase in May precipitation made a dominant contribution to that increase. Further analysis indicates that the increase in May precipitation is concurrent with the decline in Arctic sea ice concentration (SIC) over the Barents Sea; both variables show an interdecadal shift around the early 2000s. Physical analysis based on observations and numerical simulations demonstrates that a decline in the Barents Sea SIC could excite a Rossby wave train propagating southeastward across the Mongolia‐Baikal region and reaching northeast China, thereby inducing a zonal anticyclone–cyclone–anticyclone teleconnection pattern over mid‐ to high‐latitude Eurasia. Under the influence of such a teleconnection pattern, significant southerlies prevail over northeast China, bringing warm and wet air to the region; in addition, the local atmospheric instability and upward motion are also increased. The changes in the moisture and dynamic conditions favour the increase in May precipitation over northeast China. Furthermore, SIC anomalies in the Barents Sea persist from late winter to spring; therefore, the SIC signal could provide signals for predictions of the interdecadal changes in May precipitation over northeast China.

Three new diterpenoids from Euphorbia peplus - Yan-Ni Chen; Qing-Yun Lu; Dong-Mei Li; Ying-Yao Li; Xue-Xue Pu; Bo-Ting Li; Xiao-Han Tang; Hong-Yu Tang; Shuai Liu; Lei Yang; Yu Zhang; Ying-Tong Di; et al. (Natural Product Research, 2021)

Two new 7, 20-epoxy- ent -kauranes from the aerial parts of Isodon eriocalyx - Shu-Ying Li; Li-Hua Zhu; Zheng-Yun Rao; Chao-Jun Wang; Min Jiang; Jian Zhang; Zhi-Qi Yin (Natural Product Research, 2021)

A single nucleotide polymorphism in an R2R3 MYB transcription factor gene triggers the male sterility in soybean ms6 (Ames1) - Junping Yu; Guolong Zhao; Wei Li; Ying Zhang; Peng Wang; Aigen Fu; Limei Zhao; Chunbao Zhang; Min Xu (Theoretical and Applied Genetics, 2021)
Key message Identification and functional analysis of the male sterile gene MS6 in Glycine max . Abstract Soybean ( Glycine max (L.) Merr . ) is an important crop providing vegetable oil and protein. The male sterility-based hybrid breeding is a promising method for improving soybean yield to meet the globally growing demand. In this research, we identified a soybean genic male sterile locus, MS6 , by combining the bulked segregant analysis sequencing method and the map-based cloning technology. MS6 , highly expressed in anther, encodes an R2R3 MYB transcription factor (GmTDF1-1) that is homologous to Tapetal Development and Function 1, a key factor for anther development in Arabidopsis and rice. In male sterile ms6 (Ames1), the mutant allele contains a missense mutation, leading to the 76th leucine substituted by histidine in the DNA binding domain of GmTDF1-1. The expression of soybean MS6 under the control of the AtTDF1 promoter could rescue the male sterility of attdf1 but ms6 could not. Additionally, ms6 overexpression in wild-type Arabidopsis did not affect anther development. These results evidence that GmTDF1-1 is a functional TDF1 homolog and L76H disrupts its function. Notably, GmTDF1-1 shows 92% sequence identity with another soybean protein termed as GmTDF1-2, whose active expression also restored the fertility of attdf1 . However, GmTDF1-2 is constitutively expressed at a very low level in soybean, and therefore, not able to compensate for the MS6 deficiency. Analysis of the TDF1-involved anther development regulatory pathway showed that expressions of the genes downstream of TDF1 are significantly suppressed in ms6 , unveiling that GmTDF1-1 is a core transcription factor regulating soybean anther development.

MamZ protein plays an essential role in magnetosome maturation process of Magnetospirillum gryphiswaldense MSR-1 - Sha Wu; Qing Wang; Xu Wang; Ruixue Guo; Tongwei Zhang; Yongxin Pan; Feng Li; Ying Li (Journal of Oceanology and Limnology, 2021)

Comparison of the Bulk and Rhizosphere Soil Prokaryotic Communities Between Wild and Reintroduced Manglietiastrum sinicum Plants, a Threatened Species with Extremely Small Populations - Dai-Fa Su; Qing-Qing Shen; Jun-Yu Yang; Zhi-Ying Li; Wei Xiao; Yong-Xia Wang; Zhang-Gui Ding; Xiao-Long Cui (Current Microbiology, 2021)

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

First identification and genomic characterization of equine hepacivirus subtype 2 in China - Yuxin Chen; Siqi Cai; Ying Zhang; Zhiying Lai; Lintao Zhong; Xingrong Sun; Shoujun Li; Gang Lu (Archives of Virology, 2021)

Evaluation of Surface Relative Humidity in China from the CRA-40 and Current Reanalyses - Jingpeng Zhang; Tianbao Zhao; Zhi Li; Chunxiang Li; Zhen Li; Kairan Ying; Chunxiang Shi; Lipeng Jiang; Wenyu Zhang (Advances in Atmospheric Sciences, 2021)

Induced production of a new polyketide in Penicillium sp. HS-11 by chemical epigenetic manipulation - You-Min Ying; Ling Li; Hang-Fei Yu; Yi-Lian Xu; Lu Huang; Wei Mao; Cui-Ping Tong; Zhi-Dong Zhang; Zha-Jun Zhan; Yun Zhang (Natural Product Research, 2021)

Expression of the SPL-like gene LaSPL9 in Japanese larch (Larix leptolepis) is regulated by miR156 during somatic embryogenesis - Li-feng Zhang; Yan-ru Fan; Qian Lan; Li-wang Qi; Su-ying Han (Trees, 2021)

Metabolic engineering of Escherichia coli for efficient ectoine production - Shuyan Zhang; Yu Fang; Lifei Zhu; Hedan Li; Zhen Wang; Ying Li; Xiaoyuan Wang (Systems Microbiology and Biomanufacturing, 2021)

Genome-wide analysis and characterization of R2R3-MYB family in pigeon pea (Cajanus cajan) and their functional identification in phenylpropanoids biosynthesis - Jie Yang; Su Zhang; Hongquan Li; Litao Wang; Ying Liu; Lili Niu; Qing Yang; Dong Meng; Yujie Fu (Planta, 2021)

Responses of leaf litter decomposability to nitrogen and phosphorus additions are associated with cell wall carbohydrate composition in a subtropical plantation - Xiang-Min Fang; Xiu-Lan Zhang; Ying-Ying Zong; Wen-Qing Li; Jian-Jun Li; Li-Ping Guo; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

Comparison on characterization and antioxidant activity of exopolysaccharides from two Porphyridium strains - Wei-Nan Wang; Yi Li; Ying Zhang; Wen-Zhou Xiang; Ai-Fen Li; Tao Li (Journal of Applied Phycology, 2021)

Changes in Brain Functional Network Connectivity in Adult Moyamoya Diseases - Gaoxing Zheng; Yu Lei; Yuzhu Li; Wei Zhang; Jiabin Su; Xiaoying Qi; Liang Chen; Xin Zhang; Yuxiang Gu; Yuguo Yu; Ying Mao (Cognitive Neurodynamics, 2021)

Retraction Note to: CiRS-126 inhibits proliferation of ovarian granulosa cells through targeting the miR-21-PDCD4-ROS axis in a polycystic ovarian syndrome model - Jiafeng Lu; Ying Xue; Yuhang Wang; Yang Ding; Qinyan Zou; Min Pan; Longwei Qiao; Chunhua Zhang; Qinyu Ge; Ting Wang; Hong Li (Cell and Tissue Research, 2021)

Serum levels of polychlorinated biphenyls and stroke risk among Chinese: a hospital-based case–control study - Ping Li; Ying Dan; Shuangying Li; Qiaolian Zhang; Ya Su; Mei Lu (Acta Neurologica Belgica, 2021)

Geniposide-Loaded Liposomes for Brain Targeting: Development, Evaluation, and In Vivo Studies - Jinyan Wan; Yu Long; Songyu Liu; Yulu Zhang; Yan Xiang; Dan Li; Ai Shi; Yu Shuang; Ying Li; Yanan He; Nan Li; Yongmei Guan (AAPS PharmSciTech, 2021)

A new indole alkaloid with HUVEC proliferation activities from Nauclea officinalis - Shi-Ying Mai; Yong-Hui Li; Xu-Guang Zhang; Yi-Ran Wang; Jun-Qing Zhang; An Jia (Natural Product Research, 2021)

Two new norsesquiterpenoids with estrogenic activity from the stems and leaves of Dioscorea oppositifolia L - Ying-Jie Ren; Yan-Gang Cao; Meng-Nan Zeng; Bei-Bei Zhang; Yan-Ling Liu; Meng-Na Wang; Yan-Li Zhang; Wei-Sheng Feng; Xiao-Ke Zheng (Natural Product Research, 2021)

Chemical constituents from Urtica fissa stem and their inhibitory effects on α -glucosidase activity - Ying Zhang; Jinzhao Liu; Zixian Guo; Xiaobo Li; Mengyue Wang (Natural Product Research, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Reduced Firing of Nucleus Accumbens Parvalbumin Interneurons Impairs Risk Avoidance in DISC1 Transgenic Mice - Xinyi Zhou; Bifeng Wu; Wenhao Liu; Qian Xiao; Wei He; Ying Zhou; Pengfei Wei; Xu Zhang; Yue Liu; Jie Wang; Jufang He; Zhigang Zhang; et al. (Neuroscience Bulletin, 2021)
A strong animal survival instinct is to approach objects and situations that are of benefit and to avoid risk. In humans, a large proportion of mental disorders are accompanied by impairments in risk avoidance. One of the most important genes involved in mental disorders is disrupted-in-schizophrenia-1 ( DISC1 ), and animal models in which this gene has some level of dysfunction show emotion-related impairments. However, it is not known whether DISC1 mouse models have an impairment in avoiding potential risks. In the present study, we used DISC1-N terminal truncation ( DISC1-N TM ) mice to investigate risk avoidance and found that these mice were impaired in risk avoidance on the elevated plus maze (EPM) and showed reduced social preference in a three-chamber social interaction test. Following EPM tests, c-Fos expression levels indicated that the nucleus accumbens (NAc) was associated with risk-avoidance behavior in DISC1-N TM mice. In addition, in vivo electrophysiological recordings following tamoxifen administration showed that the firing rates of fast-spiking neurons (FS) in the NAc were significantly lower in DISC1-N TM mice than in wild-type (WT) mice. In addition, in vitro patch clamp recording revealed that the frequency of action potentials stimulated by current injection was lower in parvalbumin (PV) neurons in the NAc of DISC1-N TM mice than in WT controls. The impairment of risk avoidance in DISC1-N TM mice was rescued using optogenetic tools that activated NAc PV neurons. Finally, inhibition of the activity of NAc PV neurons in PV-Cre mice mimicked the risk-avoidance impairment found in DISC1-N TM mice during tests on the elevated zero maze. Taken together, our findings confirm an impairment in risk avoidance in DISC1-N TM mice and suggest that reduced excitability of NAc PV neurons is responsible.

Acupuncture Ameliorates Neuronal Cell Death, Inflammation, and Ferroptosis and Downregulated miR-23a-3p After Intracerebral Hemorrhage in Rats - Ying Kong; Shulin Li; Miao Zhang; Wenting Xu; Qiuxin Chen; Lihong Zheng; Peng Liu; Wei Zou (Journal of Molecular Neuroscience, 2021)

Adaptive Total-Variation Regularized Low-Rank Representation for Analyzing Single-Cell RNA-seq Data - Jin-Xing Liu; Chuan-Yuan Wang; Ying-Lian Gao; Yulin Zhang; Juan Wang; Sheng-Jun Li (Interdisciplinary Sciences: Computational Life Sciences, 2021)

Study on the community structure and function of anaerobic granular sludge under trichloroethylene stress - Qingjuan Meng; Pengfei Li; Jianhua Qu; Ying Liu; Yifan Wang; Zhaobo Chen; Ying Zhang (Ecotoxicology, 2021)

Biodegradation of Di-n-butyl phthalate in rhizosphere and growth-promoting effect of Cucumis sativus Linn. by a novel Pseudomonas sp. DNB-S1 - Shuqin Li; Lei Wang; Ying Li; Fuxin Huang; Hui Yu; Ying Zhang; Rui Li; Zhaobo Chen; Ningrui Wei; Zhengzhe Yu (Ecotoxicology, 2021)

Numerical modeling of 3D DC resistivity method in the mixed space-wavenumber domain - Shi-Kun Dai; Jia-Xuan Ling; Qing-Rui Chen; Kun Li; Qian-Jiang Zhang; Dong-Dong Zhao; Ying Zhang (Applied Geophysics, 2021)

Triterpene saponins from tea seed pomace ( Camellia oleifera Abel) and their cytotoxic activity on MCF-7 cells in vitro - Xin-Fu Zhang; Ying-Ying Han; Tai-Mei Di; Li-Ping Gao; Tao Xia (Natural Product Research, 2021)

A new benzophenone with biological activities from metabolites of butyrolactone I in rat faeces - Bing Liu; Ning Chen; Ying Xu; Jia-Wei Zhang; Yuan Sun; Li-Zhu Zhao; Yu-bin Ji (Natural Product Research, 2021)

Correction to: Activation of Sigma-1 Receptor Enhanced Pericyte Survival Via the Interplay between Apoptosis and Autophagy: Implications for Blood–Brain Barrier Integrity in Stroke - Yuan Zhang; Xiaotian Zhang; Qiangqiang Wei; Shuo Leng; Cai Li; Bing Han; Ying Bai; Huibin Zhang; Honghong Yao (Translational Stroke Research, 2021)

Gut Microbial Metabolites in Parkinson’s Disease: Implications of Mitochondrial Dysfunction in the Pathogenesis and Treatment - Yixuan Liang; Li Cui; Jiguo Gao; Mingqin Zhu; Ying Zhang; Hong-Liang Zhang (Molecular Neurobiology, 2021)
The search for therapeutic targets for Parkinson’s disease (PD) is hindered by the incomplete understanding of the pathophysiology of the disease. Mitochondrial dysfunction is an area with high potential. The neurobiological signaling connections between the gut microbiome and the central nervous system are incompletely understood. Multiple lines of evidence suggest that the gut microbiota participates in the pathogenesis of PD. Gut microbial dysbiosis may contribute to the loss of dopaminergic neurons through mitochondrial dysfunction. The intervention of gut microbial metabolites via the microbiota-gut-brain axis may serve as a promising therapeutic strategy for PD. In this narrative review, we summarize the potential roles of gut microbial dysbiosis in PD, with emphasis on microbial metabolites and mitochondrial function. We then review the possible ways in which microbial metabolites affect the central nervous system, as well as the impact of microbial metabolites on mitochondrial dysfunction. We finally discuss the possibility of gut microbiota as a therapeutic target for PD.

Application of Plant Print Identification Technology in Salt-resistant Soybean Breeding - Yan Li; Xia Li; Zi-qi Chen; Ying Ma; Guang-yu Yang; Ying Zhang; Ming-chun Sun; Li-hong Zhang; Jin-meng Chu; Jing-mei Lu; Jun Zhu; Ji-hong You (Journal of Plant Growth Regulation, 2021)

Evaluation of field resistance to brown stripe disease in novel and major cultivated sugarcane varieties in China - Xiao-Yan Wang; Xiao-Yan Cang; Wei Qin; Hong-Li Shan; Rong-Yue Zhang; Chang-Mi Wang; Wen-Feng Li; Ying-Kun Huang (Journal of Plant Pathology, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Effects of Mn2+ on neutral lipid content, C4 pathway, and related gene expression in Phaeodactylum tricornutum - Rong-Shi Chen; Li Zhang; Feng-Juan Wei; Lan-Ying Yuan; Pu Zhao; He-Yu Wang; Yi-Fu Gong (Journal of Applied Phycology, 2021)

Gonadal lipidomics profile of an ovoviviparity teleost, black rockfish, during gonadal development - Jianshuang Li; Min Song; Haishen Wen; Ying Zhang; Yun Li; Likang Lyu; Xiaojie Wang; Xin Qi (Fish Physiology and Biochemistry, 2021)

Effect of diurnal temperature change on cardiovascular risks differed under opposite temperature trends - Pan Ma; Ying Zhang; Xinzi Wang; Xingang Fan; Lei Chen; Qin Hu; Shigong Wang; Tanshi Li (Environmental Science and Pollution Research, 2021)

Exposure to antibiotics and mental disorders in children: a community-based cross-sectional study - Jingjing Zhang; Kaiyong Liu; Liang Sun; Linsheng Yang; Xinji Liu; Yitian Zhu; Rong Wei; Zhongxiu Jin; Li Wang; Ying Ma; Sufang Wang; Annuo Liu; et al. (Environmental Geochemistry and Health, 2021)

Exogenous Glutathione Alleviates Cadmium Toxicity in Wheat by Influencing the Absorption and Translocation of Cadmium - Ge-Zi Li; Shi-Juan Chen; Na-Ying Li; Ying-Ying Wang; Guo-Zhang Kang (Bulletin of Environmental Contamination and Toxicology, 2021)
Cadmium (Cd), a toxic heavy metal, is harmful to plants and human health. Glutathione (GSH) could alleviate Cd toxicity of plant species, whereas its mechanism responsible for wheat remains poorly understood. Here, we found that exogenous GSH application significantly increased the fresh and dry weight, root elongation, chlorophyll contents, while decreased the contents of malondialdehyde (MDA) and GSH, and translocation factor of Cd compared with Cd treatment. Moreover, GSH application significantly increased activities of antioxidant enzymes and expression of related genes, which involved in GSH synthesis, especially in roots. In addition, we found that GSH application suppressed Cd-induced expression of metal transporter genes TaNramp1 , TaNramp5 , TaHMA2 , TaHMA3 , TaLCT1 and TaIRT2 in roots. Taken together, our results suggested that GSH could alleviate Cd toxicity in wheat by increasing GSH synthesis gene expression or suppressing Cd transporter genes expression, and further affecting Cd uptake and translocation in wheat plants.

Sensitive Techniques for POCT Sensing on the Residues of Pesticides and Veterinary Drugs in Food - Lin Liu; Yueying Gao; Jinghan Liu; Ying Li; Ziye Yin; Yuanyuan Zhang; Fuwei Pi; Xiulan Sun (Bulletin of Environmental Contamination and Toxicology, 2021)

Current Progress on Antibiotic Sensing Based on Ratiometric Fluorescent Sensors - Jinghan Liu; Ying Li; Lin Liu; Yueying Gao; Yuanyuan Zhang; Ziye Yin; Fuwei Pi; Xiulan Sun (Bulletin of Environmental Contamination and Toxicology, 2021)

Cross-sectional exploration of brain functional connectivity in the triadic development model of adolescents - Wenjing Xu; Fuxian Ying; Yuejia Luo; Xiao-Yong Zhang; Zhihao Li (Brain Imaging and Behavior, 2021)

MR T1 mapping for quantifying brain manganese deposition in type C hepatic encephalopathy rats - Cui Zhang; Ying Li; Jingjing Lu; Xiuying Yang; Jie Wang; Jinwei Qiang (BioMetals, 2021)

Genetic changes and evolutionary analysis of canine circovirus - Lin Wang; Yifan li; Zhiyuan Guo; Ying Yi; Han Zhang; Haikun Shangguan; Chengshi Huang; Junwei Ge (Archives of Virology, 2021)

Feeding ecology of Japanese Spanish mackerel (Scomberomorus niphonius) along the eastern coastal waters of China - Haozhi Sui; Ying Xue; Yunkai Li; Binduo Xu; Chongliang Zhang; Yiping Ren (Acta Oceanologica Sinica, 2021)

Neuroprotective triterpene saponins from the leaves of Panax notoginseng - Ji-Wu Huang; Yi-Qian Du; Chuang-Jun Li; Jing-Zhi Yang; Jie Ma; Ying-Da Zang; Nai-Hong Chen; Dong-Ming Zhang (Natural Product Research, 2021)

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

Dexmedetomidine reversed hypoxia/reoxygenation injury-induced oxidative stress and endoplasmic reticulum stress-dependent apoptosis of cardiomyocytes via SIRT1/CHOP signaling pathway - Ying Zhang; Qihong Zhao; Xiaohong Li; Fuhai Ji (Molecular and Cellular Biochemistry, 2021)

Retrospective surveillance of porcine circovirus 4 in pigs in Inner Mongolia, China, from 2016 to 2018 - Zhuo Ha; Chengdong Yu; Changzhan Xie; Guanyu Wang; Ying Zhang; Pengfei Hao; Jinfeng Li; Zhuoxin Li; Yanwei Li; Fulong Rong; Fulong Nan; He Zhang; et al. (Archives of Virology, 2021)

Biological characteristics and salt-tolerant plant growth-promoting effects of an ACC deaminase-producing Burkholderia pyrrocinia strain isolated from the tea rhizosphere - Lizhen Han; Hong Zhang; Yu Xu; Ying Li; Jing Zhou (Archives of Microbiology, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei - Ying Pang; Xiaojun Zhang; Jianbo Yuan; Xiaoxi Zhang; Manwen Su; Fuhua Li (Frontiers in Marine Science, 2021)
Glycogen synthase kinase 3 (GSK3) is a vital multifunctional molecule that is widely distributed in invertebrates and vertebrates. GSK3 is a highly conserved serine/threonine (Ser/Thr) protein kinase, which plays an important role in insulin, Wnt, and various signaling pathways. In this study, a GSK3 gene were identified in the genome of the Pacific white shrimp, Litopenaeus vannamei , and analyzed its gene structure, phylogeny, and expression profiles. The deduced LvGSK3 protein contains a highly conserved Ser/Thr protein kinase catalytic (S_TKc) domain, the LvGSK3 gene exhibited high expression in different early developmental stages, most adult tissues, and premolting stages. RNA interference of LvGSK3 significantly retarded the increment of body weight and affected the expressions of molting-related genes compared with control groups. These results will improve our understanding of the conserved structure and functions of the LvGSK3 gene and show potential applications of shrimp growth.

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

The Protective Effects of Ropivacaine Against High Glucose-induced Brain Microvascular Endothelial Injury by Reducing MMPs and Alleviating Oxidative Stress - Hu Lv; Qian Cheng; Ying Li; Yue Zhang; Jiawei Chen; Wei Chen (Neurotoxicity Research, 2021)

Transcutaneous Auricular Vagus Nerve Stimulation: From Concept to Application - Yu Wang; Shao-Yuan Li; Dan Wang; Mo-Zheng Wu; Jia-Kai He; Jin-Ling Zhang; Bin Zhao; Li-Wei Hou; Jun-Ying Wang; Lei Wang; Yi-Fei Wang; Yue Zhang; et al. (Neuroscience Bulletin, 2021)

Research on displacement prediction of step-type landslide under the influence of various environmental factors based on intelligent WCA-ELM in the Three Gorges Reservoir area - Yong-gang Zhang; Xin-quan Chen; Rao-ping Liao; Jun-li Wan; Zheng-ying He; Zi-xin Zhao; Yan Zhang; Zheng-yang Su (Natural Hazards, 2021)

Evaluating the Friendliness of Pedestrian Footbridges Using Visibility Analysis: A Case Study in Wuhan - Jun Li; Shuang Wu; Zhiwei Luo; Jingyang Hou; Wenbo Zhang; Xueye Chen; Junru Su; Shen Ying (Journal of Geovisualization and Spatial Analysis, 2021)

Accurately Discriminating COVID-19 from Viral and Bacterial Pneumonia According to CT Images Via Deep Learning - Fudan Zheng; Liang Li; Xiang Zhang; Ying Song; Ziwang Huang; Yutian Chong; Zhiguang Chen; Huiling Zhu; Jiahao Wu; Weifeng Chen; Yutong Lu; Yuedong Yang; et al. (Interdisciplinary Sciences: Computational Life Sciences, 2021)

Performance of VITEK 2, E-test, Kirby–Bauer disk diffusion, and modified Kirby–Bauer disk diffusion compared to reference broth microdilution for testing tigecycline susceptibility of carbapenem-resistant K. pneumoniae and A. baumannii in a multicenter study in China - Dandan Yin; Yan Guo; Min Li; Wenjuan Wu; Jin Tang; Ying Liu; Feng Chen; Yuxing Ni; Jingyong Sun; Hong Zhang; Hu Zhao; Fupin Hu (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Intraspecific recurrent selection in V. vinifera: an effective method for breeding of high quality, disease-, cold-, and drought -resistant grapes - Zhi-Lei Wang; Ting-Ting Xue; Fei-Fei Gao; Liang Zhang; Xing Han; Ying Wang; Miao Hui; Dong Wu; Hua Li; Hua Wang (Euphytica, 2021)

Quantitative human risk analysis of 2015 Shenzhen dump failure considering influence of urbanization - Shuai Zhang; Ying Liu; Bate Bate; Da-lei Peng; Can Li; Liang-tong Zhan (Journal of Mountain Science, 2021)

Nutrigenomics reveals potential genetic underpinning of diverse taste preference of Chinese men - Zhouhai Zhu; Junpu Mei; Silong Sun; Sheming Lu; Meng Li; Ying Guan; Ying Chen; Yuqiong Xu; Tao Zhang; Fengxue Shi; Xuemei Li; Mingming Miao; et al. (Genes & Genomics, 2021)

Catalytic Hydroprocessing of White Pine Pyrolysis Bio-Oil over Cobalt-Molybdenum Carbide in a Continuous Packed-Bed Reactor - Rui Li; Zhixin Zhao; Bo Zhang; Xiaozheng Sun; Zhen Zhang; Ying Zhang; Haitao Chen; Qiangu Yan (BioEnergy Research, 2021)

RETRACTED ARTICLE: The evolution of spatial and temporal patterns of Zhengzhou ecological network based on MSPA - Xiao Zhe-tao; Zhang Wan-ying; HAO Li-jun (Arabian Journal of Geosciences, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Probiotics supplementation improves hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes mellitus: An update of meta-analysis - Tingting Liang; Lei Wu; Yu Xi; Ying Li; Xinqiang Xie; Congcong Fan; Lingshuang Yang; Shuanghong Yang; Xuefeng Chen; Jumei Zhang; Qingping Wu (Critical Reviews in Food Science and Nutrition, 2021)

Design of supercontinuum laser hyperspectral light detection and ranging (LiDAR) (SCLaHS LiDAR) - Guoqing Zhou; Xiang Zhou; Youjian Song; Donghui Xie; Long Wang; Guangjian Yan; Minglie Hu; Bowen Liu; Weidong Shang; Chenghu Gong; Cheng Wang; Huaguo Huang; et al. (International Journal of Remote Sensing, 2021)

Sesquiterpenoids from Pilea cavaleriei - Yong Zhou; Ling-Yu Li; Xu Yin; Qing-Ying Zhang; Hong Liang; Peng-Fei Tu (Natural Product Research, 2021)

Elucidating the Effect of Fine Lactose Ratio on the Rheological Properties and Aerodynamic Behavior of Dry Powder for Inhalation - Ying Sun; Lu Qin; Jiayi Li; Jian Su; Ruxiao Song; Xin Zhang; Jian Guan; Shirui Mao (The AAPS Journal, 2021)

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

Antifungal Effect of Long Noncoding RNA 9708-1 in the Vulvovaginal Candidiasis Murine Model - Ying Wu; Lisha Jiang; Lingling Zhang; Xia Liu; Lina Yan; Ting Luan; Can Rui; Zhiyuan Mao; Chong Fan; Yu Liu; Ping Li; Xin Zeng (Mycopathologia, 2021)
Vulvovaginal candidiasis (VVC) caused by Candida spp. affects 70–75% of women at least once during their lives. We aim to elucidate the potential mechanism of VVC and investigate the therapeutic effects of long noncoding RNA 9708-1. Female BALB/c mice were randomized to four treatment groups, including the blank control group, VVC control group, vehicle control group and lncRNA 9708-1-overexpressed group. Mice were euthanized on Day 4, Day 7 and Day 14 after treatment. Colony-forming unit (CFU) was measured, and the inflammation was detected by hematoxylin and eosin (H&E). Gene and protein expression levels of lncRNA 9708-1 and FAK were determined by real-time PCR, Western blot and immunohistochemistry. The overexpression of lncRNA 9708-1 significantly decreased the fungal load from Day 4 to 7. H&E staining indicated that the impaired histological profiles were improved in lncRNA 9708-1-overexpressed group. LncRNA 9708-1 led to a significant increase in FAK level of vagina tissue which is expressed mainly in epithelial basal layer. This study suggests that lncRNA 9708-1 played a protective role on murine experimental VVC by upregulating the expression levels of FAK.

Development of a pyrF-based counterselectable system for targeted gene deletion in Streptomyces rimosus - Yiying Yang; Qingqing Sun; Yang Liu; Hanzhi Yin; Wenping Yang; Yang Wang; Ying Liu; Yuxian Li; Shen Pang; Wenxi Liu; Qian Zhang; Fang Yuan; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

High-resolution estimation of ambient sulfate concentration over Taiwan Island using a novel ensemble machine-learning model - Lulu Cui; Qingwei Ma; Rui Li; Hongbo Fu; Ziyu Zhang; Liwu Zhang; Ying Chen (Environmental Science and Pollution Research, 2021)

Molecular Characterization of Hsp47 in Grass Carp (Ctenopharyngodon idella) and Its Correlation with Type I Collagen in Response to Fish Aerobic Exercise - Xiao Liang; Ying Wan; Zhiyuan Shen; Yanmei Liu; Dapeng Li; Li Li; Rong Tang; Xi Zhang (Fishes, 2021)
Heat shock protein 47 (Hsp47) is a collagen-specific molecular chaperone that is indispensable for molecular maturation of collagen. In this study, hsp47 and hsp47-like cDNAs were cloned and characterized in grass carp (Ctenopharyngodon idella). The cDNAs were 1212 and 1218 base pairs long, respectively, and included an open reading frame encoding 403 and 405 amino acids. The molecular phylogeny based on the deduced amino acid sequences indicated that the correct sequences of the hsp47 and hsp47-like cDNA were obtained and the deduced proteins clustered distinctly into teleost clades. Primary structure analysis and characterization of Hsp47 and Hsp47-like shared the basic structure and biofunctions of Hsp47 in vertebrates. The spatial pattern of gene expression revealed that hsp47 and hsp47-like were relatively ubiquitous in different tissues and highly expressed in heart and skin. The expression levels of hsp47 and hsp47-like and type I collagen mRNAs varied similarly in different tissues. Type I collagen content increased significantly with the increase of water velocity in the muscle of grass carp in response to aerobic exercise. Among the gene expression changes of hsp47, hsp47-like, col1a1 and col1a2 in muscle that occurred in response to aerobic exercise, the change of type I collagen was most strongly correlated with hsp47 expression. Additionally, col1a1 showed the highest correlation with hsp47-like and col1a2 showed the highest correlation with hsp47. These findings suggest that grass carp Hsp47 and Hsp47-like are closely related to type I collagen synthesis. This study firstly suggests fish aerobic exercise can improve type I collagen content and Hsp47 gene expression in muscle of grass carp.

Two novel flavonoids from the leaves of Rhododendron dauricum L. with their inhibition of TNF-α production in LPS-induced RAW 264.7 cells - Chao Ye; Mei Jin; Chunshi Jin; Rongshen Wang; Jiaming Wang; Ying Zhang; Sainan Li; Jinfeng Sun; Wei Zhou; Gao Li (Natural Product Research, 2021)

Effectiveness of Water Management in Producing Cadmium-Safe Rice in Soils of Different Contamination Levels and Physicochemical Properties - Weisheng Lu; Dongqin Li; Ying Liu; Guijie Li; Yang Zhao; Qiuhua Zhang; Zulei Zeng; Huaxing Li; Guikui Chen (Water, Air, & Soil Pollution, 2021)

Comparison of Metabolic Profiling of Arabidopsis Inflorescences Between Landsberg erecta and Columbia, and Meiosis-Defective Mutants by 1H-NMR Spectroscopy - Xiang Li; Hongkuan Wang; Ying Wang; Limin Zhang; Yingxiang Wang (Phenomics, 2021)

A novel homozygous nonsense mutation in the CA2 gene (c.368G>A, p.W123X) linked to carbonic anhydrase II deficiency syndrome in a Chinese family - Yan Yang; Nie Tang; Ying Zhu; Lei Zhang; Xu Cao; Limei Liu; Wei Xia; Pengqiu Li; Yi Yang (Metabolic Brain Disease, 2021)

Editorial Expression of Concern: The bio-mitigation of acetochlor in soil using Rhodopseudomonas capsulata in effluent after wastewater treatment - Pan Wu; Bo Cao; Ying Zhang; Wenbin Li; Yanling Wang; Yuan Wu; Ning Li (Journal of Soils and Sediments, 2021)

Calcium signalling mediated the regulation of growth and polysaccharide accumulation by light quality in Dendrobium officinale protocorms - Ting Lei; Suping Gao; Xiao Lin; Kaihui Zhang; Yingqi Liu; Wenji Li; Di Hu; Xiaofang Yu; Mingyan Jiang; Qibing Chen; Ying Sun (Horticulture, Environment, and Biotechnology, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

Growth differentiation factor-15 and lactoferrin immuno-expression in breast cancer: relationship with body iron-status and survival outcome - Zheng Zhang; Hao-Jie Jiang; Huan-Huan Yang; Jin-Jin Ren; Guo-Qin Jiang; Jia-Ying Xu; Li-Qiang Qin (BioMetals, 2021)

Litter addition and understory removal influenced soil organic carbon quality and mineral nitrogen supply in a subtropical plantation forest - Xiang-Min Fang; G. Geoff Wang; Zhi-Jun Xu; Ying-Ying Zong; Xiu-Lan Zhang; Jian-Jun Li; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

Groundwater sources, flow patterns, and hydrochemistry of the Central Yinchuan Plain, China - Ying Li; Ping Wu; Xiao-Qin Huang; Bo Zhang; Zhao-Xiang Xu; Yang Li; Jie Li; Lu-Chen Wang; Yu-Fang Sun; Xu-Chen Meng; Cheng-Wen Wang; Zi-Zhao Cai (Hydrogeology Journal, 2021)

Gene polymorphism of chalcone isomerase influence the accumulation of flavonoids in licorice (Glycyrrhiza spp.) - Xiaodong Zhang; Shaokai Tian; Lin Qi; Wendong Li; Jiaming Hou; Lin Yang; Zhixin Zhang; Ying Liu (Genetic Resources and Crop Evolution, 2021)

Temporal variation of airborne fungi in university library rooms and its relation to environmental parameters and potential confounders - Dingmeng Wu; Ying Zhang; Chenbo Zhao; Angui Li; Li’an Hou; Yu Tian; Jing Xiong; Ran Gao (Environmental Science and Pollution Research, 2021)

Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications - Dingyu Wang; Li Sun; Guowei Zhang; Yang Liu; Zhaoguang Liang; Jing Zhao; Shuangli Yin; Mengqi Su; Song Zhang; Ying Wei; He Liu; Desen Liang; et al. (Cardiovascular Toxicology, 2021)

Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease - Meng Zhang; Mengying Wang; Hui Wang; Ying Zhang; Zhengzheng Li; Yiping Feng; Yinan Liu; Yue Liu; Yucheng Liao; Wenjun Wang; Qian Fang; Jinghong Chen (Biological Trace Element Research, 2021)

Arbuscular mycorrhizal colonization rate of an exotic plant, Galinsoga quadriradiata, in mountain ranges changes with altitude - Gang Liu; Rui-Ling Liu; Wen-Gang Zhang; Ying-Bo Yang; Xiao-Qiong Bi; Ming-Zhu Li; Xiao-Yan Chen; Hua Nie; Zhi-Hong Zhu (Mycorrhiza, 2021)

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China - Qing-Hai Wang; Xiang-Ying Li; Ting-Ting Xu; Meng-Ai Zhang; Yu-Hui Yang; Pei-Bo Feng; Su-Su Fan; Zhen-Yu Liu (Journal of General Plant Pathology, 2021)

Host genetics and gut microbiota cooperatively contribute to azoxymethane-induced acute toxicity in Collaborative Cross mice - Chenhan Zhong; Li He; Sun-Young Lee; Hang Chang; Yuqing Zhang; David W. Threadgill; Ying Yuan; Fuling Zhou; Susan E. Celniker; Yankai Xia; Antoine M. Snijders; Jian-Hua Mao (Archives of Toxicology, 2021)

Improved seismoacoustic analysis model and its application to source parameter inversion of near-surface small-yield chemical explosions - Zhang Liang-Yong; Li Xin; Liang Xu-Bin; Wang Tong-Dong; Tang Shi-Ying; Zhang De-Zhi; Zeng Xin-Wu (Applied Geophysics, 2021)

Prestack seismic stochastic inversion based on statistical characteristic parameters - Wang Bao-Li; Lin Ying; Zhang Guang-Zhi; Yin Xing-Yao; Zhao Chen (Applied Geophysics, 2021)

Antioxidant and anti-inflammatory constituents from Flos populi - Yong Hou; Guangjie Zhang; Min Li; Bowen Li; Li Chen; Ying Tian; Shijun Liu; Bin Li; Junxing Dong (Natural Product Research, 2021)

Network pharmacology uncovers anti-cancer activity of vibsane-type diterpenes from Viburnum odoratissimum - Ying-Ying Zhang; Jing-Jie Chen; Dan-Qi Li; Yan- Zhang; Xiao-Bo Wang; Guo-Dong Yao; Shao-Jiang Song (Natural Product Research, 2021)

Transcriptional and post-transcriptional regulation of the miR171-LaSCL6 module during somatic embryogenesis in Larix kaempferi - Qiao-Lu Zang; Yao Zhang; Su-Ying Han; Wan-Feng Li; Li-Wang Qi (Trees, 2021)
Key message Expression analysis of Larix kaempferi mature miR171s and their primary transcripts and target gene LaSCL6 during somatic embryogenesis revealed the transcriptional and post-transcriptional regulation of the miR171- LaSCL6 module. Abstract Somatic embryogenesis provides a useful experimental system for studying the regulatory mechanisms of plant development. The level and activity of microRNA171 (miR171) fluctuate during somatic embryogenesis in Larix kaempferi , but the underlying mechanisms are still unclear. Here, in L. kaempferi we identified five members of the miR171 family, which cleave LaSCL6 mRNA at different sites. In addition, we improved the method of measuring miRNA activity in a more direct way. Furthermore, we measured the expression patterns of mature miR171s and their primary transcripts during somatic embryogenesis in L. kaempferi and found that their patterns differed, indicating that the transcription of MIR171 genes and the subsequent cleavage of their intermediate products are regulated. Taken together, our findings not only offer a means to study the regulation of miRNA activity, but also provide further insight into the regulation of L . kaempferi somatic embryogenesis by miR171- LaSCL6 .

The MYB transcription factor Baymax1 plays a critical role in rice male fertility - Xiao-Jiao Xiang; Lian-Ping Sun; Ping Yu; Zheng-Fu Yang; Pei-Pei Zhang; Ying-Xin Zhang; Wei-Xun Wu; Dai-Bo Chen; Xiao-Deng Zhan; Riaz-Muhammad Khan; Adil Abbas; Shi-Hua Cheng; et al. (Theoretical and Applied Genetics, 2021)

Application of soil phytoliths to the quantitative characterization of temperate grassland ecosystems: a case study in Northeast China - Guizai Gao; Dehui Li; Dongmei Jie; Nannan Li; Lidan Liu; Hongyan Liu; Jiangyong Wang; Honghao Niu; Meng Meng; Ying Liu; Guihua Zhang (Plant and Soil, 2021)

Sex Differences in Electrophysiological Properties of Mouse Medial Preoptic Area Neurons Revealed by In Vitro Whole-cell Recordings - Wen Zhang; Shuai-shuai Li; Ying Han; Xiao-Hong Xu (Neuroscience Bulletin, 2021)

First report of turnip mosaic virus on yellow passion fruit in China - Li Juan Chen; Xing Xing Zhang; Ying Lin Lu; Yu Xing An (Journal of Plant Pathology, 2021)

The role of MYB proto-oncogene like 2 in tamoxifen resistance in breast cancer - Xia Li; Xi Zhang; Cong-Cong Wu; Ping-Ping Li; Yi-Mou Fu; Li-Hua Xie; Shuang-Shuang Sun; Ying-Ying Zhou; Bao-Ling Zhu (Journal of Molecular Histology, 2021)

Effects of sulfur limitation on nitrogen and sulfur uptake and lipid accumulation in Scenedesmus acuminatus - Qianya Wang; Ying Zhang; Huijuan Wu; Ning Xu; Aifen Li (Journal of Applied Phycology, 2021)

Gentianella acuta prevents acute myocardial infarction induced by isoproterenol in rats via inhibition of galectin-3/TLR4/MyD88/NF-кB inflammatory signalling - Jia-Huan Sun; Hong-Xia Yang; Ting-Ting Yao; Yuan Li; Lin Ruan; Geng-Rui Xu; Chuang Zhang; Guo-Xin Guo; Ai-Ying Li (Inflammopharmacology, 2021)

The Association Between Trace Elements Exposure and the Cognition in the Elderly in China - Ling Gu; Jinhui Yu; Yong Fan; Sufang Wang; Linsheng Yang; Kaiyong Liu; Qunan Wang; Guimei Chen; Dongmei Zhang; Ying Ma; Li Wang; Annuo Liu; et al. (Biological Trace Element Research, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

A trace alkaloid, oleraisoindole A from Portulaca oleracea L. and its anticholinesterase effect - Yifei Ma; Xuetao Li; Wenjie Zhang; Xixiang Ying; Didier Stien (Natural Product Research, 2021)

Development and application of a comparative risk assessment method for ranking chemical hazards in food - Ying Li; Guoxin Liang; Lei Zhang; Zhaoping Liu; Dajin Yang; Jianwen Li; Guiju Sun; Pingping Zhou (Food Additives & Contaminants: Part A, 2021)

Progressive Fine Integrated Geophysical Method for Karst Detection During Subway Construction - Maoxin Su; Ying Zhao; Yiguo Xue; Peng Wang; Teng Xia; Kai Zhang; Congcong Li (Pure and Applied Geophysics, 2021)

Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human - Ya-Xin Fan; Yuan-Cheng Chen; Yi Li; Ji-Cheng Yu; Xing-Chen Bian; Xin Li; Wan-Zhen Li; Bei-Ning Guo; Hai-Lan Wu; Xiao-Fen Liu; Yu Wang; Xiao-Yong Xu; et al. (Pharmaceutical Research, 2021)

A novel displacement prediction method using gated recurrent unit model with time series analysis in the Erdaohe landslide - Yong-gang Zhang; Jun Tang; Zheng-ying He; Junkun Tan; Chao Li (Natural Hazards, 2021)

A Novel Fluorescent Probe Based on Pyrazole-Pyrazoline for Fe (III) Ions Recognition - Ying-Peng Zhang; Xiang-Fang Li; Yun-Shang Yang; Jing-Li Wang; Yu-Chen Zhao; Ji-Jun Xue (Journal of Fluorescence, 2021)

The impact of urbanization and consumption patterns on China’s black carbon emissions based on input–output analysis and structural decomposition analysis - Zhongci Deng; Ping Kang; Zhen Wang; Xiaoling Zhang; Weijie Li; Yihan Ou; Yu Lei; Ying Dang; Zhongren Deng (Environmental Science and Pollution Research, 2021)

Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice - Hehuan Lai; Tingting Nie; Yitong Zhang; Ying Chen; Jiaqi Tao; Tingting Lin; Tangdong Ge; Fenglan Li; Hui Li (Biological Trace Element Research, 2021)

Phytochemical constituents, chemotaxonomic significance and anti-arthritic effect of Eucommia ulmoides Oliver staminate flowers - Rui Li; Lanlan Nie; Qing Wang; Danwei Ouyang; Lei Zhang; Ying Yuan; Yanlong Hong; Jianying Wang; Xiao Hu (Natural Product Research, 2020)

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Stability Assessment of Intracranial Aneurysms Using Machine Learning Based on Clinical and Morphological Features - Wei Zhu; Wenqiang Li; Zhongbin Tian; Yisen Zhang; Kun Wang; Ying Zhang; Jian Liu; Xinjian Yang (Translational Stroke Research, 2020)

TGF-β regulation of microRNA miR-497-5p and ocular lens epithelial cell mesenchymal transition - Jinda Wang; Jingshang Zhang; Ying Xiong; Jing Li; Xiaoxia Li; Jing Zhao; Guyu Zhu; Hailong He; Yusufu Mayinuer; Xiuhua Wan (Science China Life Sciences, 2020)

Overexpression of GmGolS2-1, a soybean galactinol synthase gene, enhances transgenic tobacco drought tolerance - Shuang Qiu; Jun Zhang; Jiaqi He; Wei Sha; Mingyang Li; Yan Zhao; Ying Zhai (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Connexin 36 Mediates Orofacial Pain Hypersensitivity Through GluK2 and TRPA1 - Qian Li; Tian-Le Ma; You-Qi Qiu; Wen-Qiang Cui; Teng Chen; Wen-Wen Zhang; Jing Wang; Qi-Liang Mao-Ying; Wen-Li Mi; Yan-Qing Wang; Yu-Xia Chu (Neuroscience Bulletin, 2020)

Clinical characteristics and plasma antibody titer of patients with COVID-19 in Zhejiang, China - Wei-ling Xiang; Jing-jing Cheng; Lian-peng Wu; Bing-yu Chen; Wen-xin Li; Dan-ying Qiu; Wei Zhang; Fei-hang Ge; Dong Chen; Zhen Wang (Journal of Zhejiang University-SCIENCE B, 2020)

Effects of Short-Term Application of Chemical and Organic Fertilizers on Bacterial Diversity of Cornfield Soil in a Karst Area - Ying Li; Xiuming Liu; Lin Zhang; Yuanhuan Xie; Xianli Cai; Shijie Wang; Bin Lian (Journal of Soil Science and Plant Nutrition, 2020)

High-throughput sequencing reveals the molecular mechanisms determining the stay-green characteristic in soybeans - Cheng Wang; Le Gao; Run Zhi Li; Ye Wang; Yang Ying Liu; Xin Zhang; Hao Xie (Journal of Biosciences, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Comparison Between the Gut Microbiota in Different Gastrointestinal Segments of Large-Tailed Han and Small-Tailed Han Sheep Breeds with High-Throughput Sequencing - Guangli Yang; Shuhong Zhang; Zhiqiang Li; Jie Huang; Yan Liu; Ying Liu; Qiankun Wang; Xiangyu Li; Yongfeng Yan; Ming Li (Indian Journal of Microbiology, 2020)

Psychological symptoms in Chinese nurses may be associated with predisposition to chronic disease: a cross-sectional study of suboptimal health status - Jinxiu Zhu; Wenjuan Ying; Li Zhang; Gangyi Peng; Weiju Chen; Enoch Odame Anto; Xueqing Wang; Nan Lu; Shanshan Gao; Guihai Wu; Jingyi Yan; Jianfeng Ye; et al. (EPMA Journal, 2020)
Background Suboptimal health status (SHS) is a reversible state between ideal health and illness and it can be effectively reversed by risk prediction, disease prevention, and personalized medicine under the global background of predictive, preventive, and personalized medicine (PPPM) concepts. More and more Chinese nurses have been troubled by psychological symptoms (PS). The correlation between PS and SHS is unclear in nurses. The purpose of current study is to investigate the prevalence of SHS and PS in Chinese nurses and the relationship between SHS and PS along with predisposing factors as well as to discuss the feasibility of improving health status and preventing diseases according to PPPM concepts in Chinese nurses. Methods A cross-sectional study was conducted with the cluster sampling method among 9793 registered nurses in Foshan city, China. SHS was evaluated with the Suboptimal Health Status Questionnaire-25 (SHSQ-25). Meanwhile, the PS of depression and anxiety were evaluated with Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) self-assessment questionnaires. The relationship between PS and SHS in Chinese nurses was subsequently analyzed. Results Among the 9793 participants, 6107 nurses were included in the final analysis. The prevalence of SHS in the participants was 74.21% (4532/6107) while the symptoms of depression and anxiety were 47.62% (2908/6107) and 24.59% (1502/6107) respectively. The prevalence of SHS in the participants with depression and anxiety was significantly higher than those without the symptoms of depression (83.3% vs 16.7%, P < 0.001) and anxiety (94.2% vs 5.8%, P < 0.0001). The ratio of exercise habit was significantly lower than that of non-exercise habit (68.8% vs 78.4%, P < 0.001) in SHS group. Conclusions There is a high prevalence of SHS and PS in Chinese nurses. PS in Chinese nurses are associated with SHS. Physical exercise is a protective factor for SHS and PS so that the exercise should be strongly recommended as a valuable preventive measure well in the agreement with PPPM philosophy. Along with SDS and SAS, SHSQ-25 should also be highly recommended and applied as a novel predictive/preventive tool for the health measures from the perspectives of PPPM in view of susceptible population and individual screening, the predisposition to chronic disease preventing, personalization of intervention, and the ideal health state restoring.

Dynamic network connectivity predicts subjective cognitive decline: the Sino-Longitudinal Cognitive impairment and dementia study - Guozhao Dong; Liu Yang; Chiang-shan R. Li; Xiaoni Wang; Yihe Zhang; Wenying Du; Ying Han; Xiaoying Tang (Brain Imaging and Behavior, 2020)

Cortical 3-hinges could serve as hubs in cortico-cortical connective network - Tuo Zhang; Xiao Li; Xi Jiang; Fangfei Ge; Shu Zhang; Lin Zhao; Huan Liu; Ying Huang; Xianqiao Wang; Jian Yang; Lei Guo; Xiaoping Hu; et al. (Brain Imaging and Behavior, 2020)
Mapping the relation between cortical convolution and structural/functional brain architectures could provide deep insights into the mechanisms of brain development, evolution and diseases. In our previous studies, we found a unique gyral folding pattern, termed a 3-hinge, which was defined as the conjunction of three gyral crests. The uniqueness of the 3-hinge was evidenced by its thicker cortex and stronger fiber connections than other gyral regions. However, the role that 3-hinges play in cortico-cortical connective architecture remains unclear. To this end, we conducted MRI studies by constructing structural cortico-cortical connective networks based on a fine-granular cortical parcellation, the parcels of which were automatically labeled as 3-hinge, 2-hinge (ordinary gyrus) or sulcus. On human brains, 3-hinges possess significantly higher degrees, strengths and betweennesses than 2-hinges, suggesting that 3-hinges could serve more like hubs in the cortico-cortical connective network. This hypothesis gains supports from human functional network analyses, in which 3-hinges are involved in more global functional networks than ordinary gyri. In addition, 3-hinges could serve as ‘connector’ hubs rather than ‘provincial’ hubs and they account for a dominant proportion of nodes in the high-level ‘backbone’ of the network. These structural results are reproduced on chimpanzee and macaque brains, while the roles of 3-hinges as hubs become more pronounced in higher order primates. Our new findings could provide a new window to the relation between cortical convolution, anatomical connection and brain function.

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

LncRNA A2M-AS1 lessens the injury of cardiomyocytes caused by hypoxia and reoxygenation via regulating IL1R2 - Xue-Lian Song; Fei-Fei Zhang; Wen-Jing Wang; Xin-Ning Li; Yi Dang; Ying-Xiao Li; Qian Yang; Mei-Jing Shi; Xiao-Yong Qi (Genes & Genomics, 2020)

LncRNA NEAT1 accelerates renal mesangial cell injury via modulating the miR-146b/TRAF6/NF-κB axis in lupus nephritis - Li-Hua Zhang; Bin Xiao; Miao Zhong; Qiao Li; Jian-Ying Chen; Jie-Rou Huang; Hui Rao (Cell and Tissue Research, 2020)

Sphingosylphosphorylcholine alleviates hypoxia-caused apoptosis in cardiac myofibroblasts via CaM/p38/STAT3 pathway - Ying Li; Qi Qi; Wan-cheng Yang; Tian-liang Zhang; Chen-chen Lu; Yu-juan Yao; Wei-hua Kong; Jing Zhao (Apoptosis, 2020)

Compressive Acoustic Sound Speed Profile Estimation in the Arabian Sea - Qianqian Li; Sartaj Khan; Fanlin Yang; Ying Xu; Kai Zhang (Marine Geodesy, 2020)

Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions - Xiuxiu Li; Zhuo Chen; Guomin Zhang; Hongwei Lu; Peng Qin; Ming Qi; Ying Yu; Bingke Jiao; Xianfeng Zhao; Qiang Gao; Hao Wang; Yunyu Wu; et al. (Science China Life Sciences, 2020)

Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior - Meng-Jia Zhu; Jing Shi; Yong Chen; Guobing Huang; Xiong-Wei Zhu; Sam Zhang; Xian-Feng Huang; Guo-Qiang Song; Han-Ting Zhang; Heng-Ming Ke; James M. O’Donnell; Li-Qun Wang; et al. (Psychopharmacology, 2020)