Heme oxygenase-1 protects against endotoxin-induced acute lung injury depends on NAD+-mediated mitonuclear communication through PGC1α/PPARγ signaling pathway - Simeng He; Jia Shi; Wenming Liu; Shihan Du; Yuan Zhang; Lirong Gong; Shuan Dong; Xiangyun Li; Qiaoying Gao; Jing Yang; Jianbo Yu (Inflammation Research, 2022)

Response of submerged macrophyte Ceratophyllum demersum to the exponential phase (EP) and declining phase (DP) of toxic Microcystis aeruginosa - Jing Dong; Yue Yang; Dujuan Dai; Feihu Wang; Yang Zhang; Yuhuan Chen; Jie Yuan; Conghui Guo; Yunni Gao; Man Zhang; Xiaofei Gao; Xuejun Li (Hydrobiologia, 2022)

The effect of the nucleotides immediately upstream of the AUG start codon on the efficiency of translation initiation in sperm cells - Jiao-Jiao Shi; Yuan Cao; Qiu-Hua Lang; Yao Dong; Liu-Yuan Huang; Liu-Jie Yang; Jing-Jing Li; Xue-Xin Zhang; Dan-Yang Wang (Plant Reproduction, 2022)

A new anti-tumor cytotoxic triterpene from Ganoderma lucidum - Liping Cao; Hongliu Jin; Qi Liang; Haiyi Yang; Shuguang Li; Zhicheng Liu; Zhongwen Yuan (Natural Product Research, 2022)

Genome-Wide Identification and Expression Analysis of AAAP Gene Family in Cerasus humilis During Fruit Development - Hongbo Fu; Pengfei Wang; Junjie Du; Xiaopeng Mu; Shengyong Yuan; Yongchao Yang; Jie Li (Plant Molecular Biology Reporter, 2022)

Three new sesquiterpenoid alkaloids from the roots of Tripterygium wilfordii and its cytotoxicity - Hong Liang Ye; Yan Liu; Juan Pan; Wei Guan; Yuan Liu; Xiao Mao Li; Si Yi Wang; Adnan Mohammed Algradi; Bing You Yang; Hai Xue Kuang (Natural Product Research, 2022)

Two new terpenes from the aerial parts of Clematis chinensis Osbeck - Sun Ye; Liu Yan; Yan-Ping Sun; Xiao-Mao Li; Wang Si-Yi; Juan Pan; Wei Guan; Yuan Liu; Anam Naseem; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Comparative transcriptome analysis of the differentiating gonads in Scatophagus argus - Umar Farouk Mustapha; You-Xing Peng; Yuan-Qing Huang; Daniel Assan; Fei Zhi; Gang Shi; Yang Huang; Guang-Li Li; Dong-Neng Jiang (Frontiers in Marine Science, 2022)
The reproductive-related studies, including genetic and genomic such as gonadal transcriptome analyses, have previously focused on the adult spotted scat, with little information on juvenile fish. Transcriptomics is a powerful tool that allows for massive parallel analysis to identify differential expression and the patterns of gene expression holistically at a particular stage in a cell or tissue development. This study presents the first report on gonadal transcriptome analysis of the differentiating (juvenile; 4 months after hatch; stage I ovary and testis) spotted scat gonads. The study revealed potential reproduction and gonadal development-related genes. A total of 25936 genes were identified, of which 16248 were co-expressed, 17893 and 17258 expressed in males and females, respectively, from sequence data of testis I (n = 3) and ovary I (n = 2). A total of 6549 differentially expressed genes (DEGs) were identified between males and females. Genes attributable to male gonad development pathway such as dmrt1 , gsdf , and amh are significantly expressed in differentiating testes, while female-related genes such as foxl2, cyp19a1a, 42sp50 and sox3 were expressed considerably in differentiating ovaries. In addition, dmrt1/dmrt1y was not expressed in the female (FPKM=0.00), while its paralog dmrt1b was expressed in both males and females. In the male pathway, dmrt1y and gsdf are critical for sex determination and maintenance while foxl2/foxl3 and cyp19a1a are critical in the female development pathway. The current studies provide an insight into the expression patterns of sex and gonadal-related genes in differentiating gonads of spotted scat.

MiR-30c-1-3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms - Lin Yang; Hong-Gang Sui; Meng-Meng Wang; Jia-Yin Li; Xiao-Feng He; Jing-Yuan Li; Xiao-Zeng Wang (Journal of Molecular Medicine, 2022)
Abdominal aortic aneurysm (AAA) can be fatal if ruptured, but there is no predictive biomarker. Our aim was to evaluate the prognostic potential of microRNAs (miRNAs/miRs) in an AAA mouse model and patients with unruptured AAA (URAAA) and ruptured AAA (RAAA). Among the 64 miRNAs differentially expressed in mice with AAA compared to control, miR-30c-1-3p, miR-432-3p, miR-3154, and miR-379-5p had high homology with human miRNAs. MiR-30c-1-3p plasma levels were significantly lower in patients with RAAA than in those with URAAA or control and tended to negatively correlate with the maximum aortic diameter ( r = −0.3153, P = 0.06109). MiR-30c-1-3p targeted matrix metalloproteinase ( MMP)-9 mRNA through the coding region and downregulated its expression in vitro. MMP-9 plasma concentrations were significantly higher in the RAAA group than in the URAAA group ( P < 0.001) and were negatively associated with miR-30c-1-3p levels ( r = −0.3671, P = 0.01981) and positively–with the maximal aortic diameter ( r = 0.6251, P < 0.0001). The optimal cutoff values for MMP-9 expression and the maximal aortic diameter were 461.08 ng/ml and 55.95 mm, with areas under the curve of 0.816 and 0.844, respectively. Our results indicate that plasma levels of miR-30c-1-3p and MMP-9 may be candidate biomarkers of AAA progression. Key messages Downregulation of miR-30c-1-3p expression and upregulation of its potential target MMP-9 are predictors of the devastation of AAA. Downregulation of miR-30c-1-3p expression and its downstream impact on MMP-9 have a potential on predicting the development and rupture of AAA.

Insertion Speed Affects the Initial Stability of Dental Implants - Yuan-Yang Hsu; Ming-Tzu Tsai; Heng-Li Huang; Lih-Jyh Fuh; Jui-Ting Hsu (Journal of Medical and Biological Engineering, 2022)
Purpose This study investigated the effects of insertion speed of dental implants on their stability. Methods Dental implants were inserted at speeds of 4, 10, 20, and 30 rpm, respectively, into artificial bones of two different bone qualities; namely, good bone (GB) and poor bone (PB). Therefore, the four insertion speeds and two bone qualities totaled eight groups, with five specimens per group. During the insertion process, the maximum insertion torque value (ITV) was measured, along with two stability parameters: periotest value (PTV) and initial stability quotient (ISQ). Results Dental implants in the GB group exhibited better stability than those in the PB group (p < 0.001). Significant differences in ITVs were observed among the four insertion speeds in both the GB and PB groups (p = 0.004 and p = 0.034, respectively). In general, the higher the insertion speed, the lower the ITV; in particular, the ITVs for implants inserted at 4 rpm were higher than those measured at 20 and 30 rpm (p = 0.008). However, regardless of the bone quality, the PTVs did not differ significantly among the four insertion speeds (p = 0.066). In both the GB and PB groups, the ISQs differed significantly differences among the four insertion speeds (p = 0.016 and p = 0.004, respectively). Conclusion The stability parameters measured for dental implants in the GB group were all higher than those measured in the PB group. In general, a higher insertion speed resulted in a lower ITV value. The PTV did not differ significantly, while the ISQ differed significantly among the four insertion speeds.

The relationship between short-term PM2.5 exposure and outpatient visits for acne vulgaris in Chongqing, China: a time-series study - Xiang Li; Lai-Xin Zhou; Li-Li Yang; Xiao-Long Huang; Nan Wang; Yue-Gu Hu; En-Jie Tang; Hua Xiao; Yu-Meng Zhou; Ya-Fei Li; Yuan-Gang Lu; Tong-Jian Cai (Environmental Science and Pollution Research, 2022)

Mental health conditions and academic burnout among medical and non-medical undergraduates during the mitigation of COVID-19 pandemic in China - Qian Yang; Yueheng Liu; Winson Fuzun Yang; Pu Peng; Shubao Chen; Yunfei Wang; Xin Wang; Manyun Li; Yingying Wang; Yuzhu Hao; Li He; Qianjin Wang; et al. (Environmental Science and Pollution Research, 2022)
The outbreak of the novel coronavirus disease 2019 (COVID-19) has posed a great impact on people’s mental health, especially for undergraduate students. This study aimed to compare the mental health conditions and academic burnout between medical and non-medical undergraduates in China when the COVID-19 pandemic is mitigating. A cross-sectional online survey was conducted among 4,972 undergraduates between October 2020 and April 2021, when the pandemic was basically under control. The survey included basic demographics information and standardized scales to evaluate depression, anxiety, perceived stress, daytime sleepiness, alcohol abuse/dependence, quality of life, fatigue, and academic burnout. Compared with medical undergraduates, non-medical undergraduates had higher rates of moderate to severe depression symptoms (29.1% vs. 17.9%, P < 0.001), moderate to severe anxiety symptoms (19.7% vs. 8.9%, P < 0.001), alcohol abuse/dependence (16.3% vs.10.3%, P < 0.001), excessive daytime sleepiness (47.4% vs. 43.4%, P = 0.018), high perceived stress (34.7% vs. 22.2%, P < 0.001), high level of fatigue (51.8% vs. 42.2%, P < 0.001), low QOL (35.8% vs. 21.4%, P < 0.001), and higher academic burnout score (59.4 vs. 57.5, P < 0.001). Being non-medical undergraduates, depression, alcohol abuse/dependence, excessive daytime sleepiness, and high perceived stress were positively associated with academic burnout, while high QOL was negatively associated with the burnout (all P < 0.001). Excessive daytime sleepiness was the strongest predictor for academic burnout.

Responses of Labile Organic Carbon and Extractable Cadmium Fractions in an Agricultural Soil Following Long-Term Repeated Application of Pig Manure and Effective Microbes - Shaocheng Si; Yuan Li; Chen Tu; Yucheng Wu; Chuancheng Fu; Shuai Yang; Yongming Luo (Bulletin of Environmental Contamination and Toxicology, 2022)

Selection and identification of a specific peptide binding to ovarian cancer cells from a phage-displayed peptide library - Qian Gao; Lirong Chen; Chenshuang Jia; Yue Yuan; Xinyao Li; Zheng Lu; Yang Feng; Ruixia Zhao; Xuewei Zhao; Yiwen Wang; Sinan Cheng; Caixia Zhang; et al. (Biotechnology Letters, 2022)

White matter alterations in heart-kidney imbalance insomnia and Jiao-Tai-Wan treatment: A diffusion-tensor imaging study - Jie Chen; Yanxuan Li; Nengzhi Xia; Caiyun Wen; Tianyi Xia; Yuandi Zhuang; Mengmeng Jiang; Yilan Xiang; Mingyue Zhang; Chenyi Zhan; Yunjun Yang; Zhengzhong Yuan; et al. (Brain Imaging and Behavior, 2022)
Previous studies have reported changes in white matter microstructures in patients with insomnia. However, few neuroimaging studies have focused specifically on white matter tracts in insomnia patients after having received treatment. In this prospective study, diffusion-tensor imaging was used in two samples of heart-kidney imbalance insomnia patients who were treated with placebo or Jiao-Tai-Wan, a traditional Chinese medicine commonly used to treat heart-kidney imbalance insomnia, to assess the changes in white matter tracts. Tract-based spatial statistical analyses were first applied to compare the changes in mean diffusivity and fractional anisotropy of white matter between 75 heart-kidney imbalance insomnia patients and 41 healthy control participants. In subsequent randomized, double-blind, placebo-controlled trials, comparisons of mean diffusivity and fractional anisotropy were also performed in 24 heart-kidney imbalance insomnia patients (8 males; 16 females; 42.5 ± 10.4 years) with Jiao-Tai-Wan and 26 heart-kidney imbalance insomnia patients (11 males; 15 females; 39.7 ± 9.4 years) with a placebo, with age and sex as covariates. Fractional anisotropy values in left corticospinal tract were increased in heart-kidney imbalance insomnia patients. Heart-kidney imbalance insomnia patients showed lower mean diffusivity and fractional anisotropy values of several white matter tracts than healthy control participants, such as the bilateral anterior limb of internal capsule, bilateral superior longitudinal fasciculus and bilateral posterior corona radiata. After being treated with Jiao-Tai-Wan, heart-kidney imbalance insomnia patients showed a trend towards reduced fractional anisotropy values in the left corticospinal tract. Jiao-Tai-Wan may improve the sleep quality by reversing the structural changes of the left corticospinal tract caused by heart-kidney imbalance insomnia.

Cohnella mopanensis sp. nov., a new Gram-negative bacterium isolated from soil in Xinping Mountain National Forest Park - Jing Tang; Jiang-Yuan Zhao; Le-Le Li; Zhang-Gui Ding; Shi-Qiang Ye; Cheng Ling; Meng-Yu Zhang; Song-Guo Liang; Jian-Yu Li; Pei-Wen Yang; Jiao Xiong; Lu-Yao Feng; et al. (Archives of Microbiology, 2022)

Lelliottia steviae sp. nov. isolated from Stevia rebaudiana Bertoni - Jing Lin; Ke Huang; Jing-Yu Huang; Yuan-Ru Xiong; Meng-Meng Wei; Na Xiao; Jia Gao; Xuan-Kai Ding; Zi-Yang Ma; Jun-Hao Sang; Ling-Xian Kong; Zhi-Yun Hong; et al. (Archives of Microbiology, 2022)

Four new polyacetylenes from the roots of Saposhnikovia divaricata - Yan Sun; Yan-Ping Sun; Yan Liu; Juan Pan; Wei Guan; Xiao-Mao Li; Yuan Liu; Anam Naseem; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Promoted reductive removal of chlorinated organic pollutants co-occurring with facilitated methanogenesis in anaerobic environment: A systematic review and meta-analysis - Jie Cheng; Jing Yuan; Shuyao Li; Xueling Yang; Zhijiang Lu; Jianming Xu; Yan He (Critical Reviews in Environmental Science and Technology, 2022)

Dogs lacking Apolipoprotein E show advanced atherosclerosis leading to apparent clinical complications - Hui Zhao; Jianping Zhao; Di Wu; Zhaolin Sun; Yang Hua; Min Zheng; Yumei Liu; Qi Yang; Xiahe Huang; Yuan Li; Yueshan Piao; Yingchun Wang; et al. (Science China Life Sciences, 2022)

Experimental Investigation of Decoupled Charge Effect on Rock Fragmentation by Blasting - Li Yuan Chi; Cheng Wang; Zong-Xian Zhang; Xuan Xu; Jun Yang (Rock Mechanics and Rock Engineering, 2022)

Hydrogen sulfide reduces cell death through regulating autophagy during submergence in Arabidopsis - Lijuan Xuan; Haijun Wu; Jian Li; Guoqiang Yuan; Yijun Huang; Chengfei Lian; Xinyu Wang; Tao Yang; Chongying Wang (Plant Cell Reports, 2022)

Co-regulation of circadian clock genes and microRNAs in bone metabolism - Tingting Li; Shihua Zhang; Yuxuan Yang; Lingli Zhang; Yu Yuan; Jun Zou (Journal of Zhejiang University-SCIENCE B, 2022)

Effect of absolute humidity on influenza activity across different climate regions in China - Li Qi; Tian Liu; Yuan Gao; Qin Li; Wenge Tang; Dechao Tian; Kun Su; Yu Xiong; Jun Yang; Luzhao Feng; Qiyong Liu (Environmental Science and Pollution Research, 2022)

Bacterioplankton community indicators for seasonal variation in a fragmented subtropical river - Biao Zhao; Peng Song; Wanling Yang; Yongzhan Mai; Haiyan Li; Qianfu Liu; Yanyi Zeng; Yuan Gao; Wanlin Du; Chao Wang (Environmental Monitoring and Assessment, 2022)

Orrella daihaiensis sp. nov., a bacterium isolated from Daihai Lake in Inner Mongolia - Kai Jiang; Bo Yuan; ChunLing Cao; ChenYing Zhang; Yang Liu; XiaoHu Hai; RuoXuan Li; KangYuan Qian; HongZhen Yang (Archives of Microbiology, 2022)

Aquapteridospora jiangxiensis, a new aquatic hyphomycetous fungus from a freshwater habitat in China - Su-Qin Peng; Yu-Lin Liu; Jun-En Huang; Xiao-Hong Li; Xin-Yi Yan; Hai-Yan Song; Yang Gao; Zhi-Jun Zhai; Yuan-Qiu Liu; Dian-Ming Hu (Archives of Microbiology, 2022)

Exploring trait–performance relationships of tree seedlings along experimentally manipulated light and water gradients - Yuanzhi Li; Yuan Jiang; Kangning Zhao; Yang Chen; Wei Wei; Bill Shipley; Chengjin Chu (Ecology, 2022)
A foundational assumption of trait‐based ecology is that individual performances should be predicted by its functional traits. However, the trait–performance relationships reported in literature were typically weak, probably due to the ignorance of interactions between traits and environments, intraspecific trait variability, and hard traits (directly linked to physiological processes of interest). We conducted an experiment of planting 900 seedlings of six tree species separately (one seedling per pot) along experimentally manipulated light and water gradients, monitored their survival and growth, and measured their morphological, photosynthetic, and hydraulic traits. Most trait–performance relationships depended on the environments, either marginally changing (weak trait × environment interaction) or even reversing (strong trait × environment interaction) along light or water gradients in our experiment. Such trait × environment interactions were more likely to be detected in growth models using individual‐level traits than models using species mean traits, but seedling growth was not better modeled with individual‐level traits than species mean traits. Additionally, none of the hard traits (photosynthetic and hydraulic traits) were better predictors than soft traits (morphological traits) modeling seedling growth and survival along light and water gradients. Our study highlights the necessities of considering trait × environment interactions when predicting response of plants to changing environments. The benefits of using individual‐level traits or hard traits to predict plant performance might be reduced or even canceled if their measurement errors are not well controlled.

Seasonal Variation of Catenary-Bead Dunes in the Yangtze River Estuary: Causes and Implications - Shuwei Zheng; Xinmeng Yuan; Suxian Yang; Heqin Cheng; Xingjie Guo; Yurong Cui; Enfeng Liu; Zijun Li (Journal of Marine Science and Engineering, 2022)
Low-angle lee-side slopes of dunes are commonly developed on the world’s riverbeds, and dune migration associated with sediment transport exert a major influence on riverine processes. However, the catenary-bead dune has been identified in the Yangtze River (YR) Estuary, featuring a higher lee-side angle. To date, the morphological variation and formation reasons of catenary-bead dunes in the YR Estuary remain uncharacterized. In this study, we used a multibeam echo system (MBES) to investigate the bedforms of the YR estuary during 2014–2015, as well as to discuss the seasonal variation of catenary-bead dunes. The results indicate that the catenary-bead dunes of the YR Estuary are characterized by growth during the flood season and extinction during the dry season. The lee-side angle is typically ~16.7°, which is larger than that of other dune types (3.7–8°) in the estuary; moreover, the catenary-bead dunes are higher than other dune types of the same length in the YR Estuary. The relationship between the dune height (H) and length (L) was found to be H = 0.1667L0.603 (R2 = 0.38), while the other dune types yielded the relationship of H = 0.0845L0.758 (R2 = 0.52). Strong runoff superimposing the ebb tide led to the development of catenary-bead dunes. Furthermore, the higher coarse sediment content (69.9–72%) and lower clay content (6.3–6.7%) of the riverbed sediment are favorable for their formation, while the higher curved crest-lines are favorable for the formation of the associated elliptical pits.

Extracellular vesicles derived from human Sertoli cells: characterizations, proteomic analysis, and miRNA profiling - Xiao-Hui Tan; Sheng-Ji Gu; Wen-Jie Tian; Wen-Peng Song; Yang-Yang Gu; Yi-Ming Yuan; Xue-Song Li; Zhong-Cheng Xin; Sae Woong Kim; Rui-Li Guan; Woong Jin Bae (Molecular Biology Reports, 2022)

Correction to: Sox10 Gene Is Required for the Survival of Saccular and Utricular Hair Cells in a Porcine Model - Jing-cui Qi; Qing-qing Jiang; Long Ma; Shuo-long Yuan; Wei Sun; Li-sheng Yu; Wei-wei Guo; Shi-ming Yang (Molecular Neurobiology, 2022)

Sox10 Gene Is Required for the Survival of Saccular and Utricular Hair Cells in a Porcine Model - Jing-cui Qi; Qing-qing Jiang; Long Ma; Shuo-long Yuan; Wei Sun; Li-sheng Yu; Wei-wei Guo; Shi-ming Yang (Molecular Neurobiology, 2022)

Characteristics of Winter Wheat Evapotranspiration in Eastern China and Comparative Evaluation of Applicability of Different Reference Evapotranspiration Models - Hao He; Ze Wu; Dandan Li; Tiancheng Zhang; Feifan Pan; Hongwei Yuan; Shangming Jiang; Zhongfeng Shi; Shuyun Yang; Fengwen Wang (Journal of Soil Science and Plant Nutrition, 2022)

Expression Profile of FaFT1 and Its Ectopic Expression in Arabidopsis Demonstrate Its Function in the Reproductive Development of Fragaria × ananassa - Wenjun Chen; Huaqing Li; Dongmei Zou; Youquan Yuan; Chaochao Li; Aijia Yang; Zhihong Zhang; Yuexue Liu (Journal of Plant Growth Regulation, 2022)

Holocene-Anthropocene transition in northwestern Yunnan revealed by records of soil erosion and trace metal pollution from the sediments of Lake Jian, southwestern China - Rui Yang; Duo Wu; Zehui Li; Zijie Yuan; Lili Niu; Huan Zhang; Jie Chen; Aifeng Zhou (Journal of Paleolimnology, 2022)

Impact of CT-Based and MRI-Based Attenuation Correction Methods on 18 F-FDG PET Quantification Using PET Phantoms - Cheng-Han Wu; Chun-Yuan Tu; Li-Chen Shen; Yueh-Hsun Lu; Bang-Hung Yang (Journal of Medical and Biological Engineering, 2022)

Stability Analysis of Upstream and Downstream Dam Slopes with Water Level Drawdown Using Response Surface Function - Dongxian Li; Liang Li; Liang Xu; Chunli Li; Kaiqi Meng; Yuan Gao; Zhengquan Yang (Geotechnical and Geological Engineering, 2022)

Adsorption Characteristics of Modified Eucalyptus Sawdust for Cadmium and Arsenic and Its Potential for Soil Remediation - Jingmin Yang; Xinran Liang; Na Jiang; Zhihong Huang; Fengli Mou; Yanqun Zu; Yuan Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Selenium Attenuates Doxorubicin-Induced Cardiotoxicity Through Nrf2-NLRP3 Pathway - Hai-Bing Yang; Zhao-Yang Lu; Wei Yuan; Wei-Dong Li; Shang Mao (Biological Trace Element Research, 2022)

Effect of Culture Period and Stocking Density on Input Demand and Scale Economies of Milkfish (Chanos chanos) Polycultures with White Shrimp (Penaeus indicus) - Wei-Tse Pai; Christian Schafferer; Jie-Min Lee; Li-Ming Ho; Yung-Hsiang Lu; Han-Chung Yang; Chun-Yuan Yeh (Fishes, 2022)
Milkfish, Chanos chanos, is one of the major inland cultured fish species in Taiwan. Variations in land resources and climate have led to the application of two distinct culture practices of milkfish polycultures with white shrimp, Penaeus indicus. This study applies a translog cost function model to analyze the production scale economy and input demand price elasticity of four milkfish polyculture systems with two different culture periods (OWC and NOWC) and two different white shrimp–milkfish fry stocking ratios (low SMR: 10–55 fry/ha; high SMR: 56–100 fry/ha). The findings show that the four milkfish polyculture systems require different operational adjustments to increase production while reducing the average culture cost. More specifically, overwinter cultures (OWC) have economies of scale. Farmers may reduce the average cost by expanding the production scale. Non-overwinter polycultures (NOWC) with high SMR are at the stage of decreasing return to scale, meaning that gains in output of milkfish cannot reduce the average cost. In terms of input factor use, farmers of OWC systems with high SMR are sensitive to fluctuations in the fry price since fry constitutes the input factor exhibiting the highest own-price elasticity. Moreover, fry and feed of OWC households with high SMR have high levels of substitutability, whereas fry and other input exhibit substitutability in OWC systems with low SMR. In NOWC farming households with high SMR, fry and capital have substitutability. It is thus recommended to modify the input factor use according to the culture mode and the white shrimp–milkfish stocking density ratio. Moreover, the study found that NOWCs have considerably higher SMR than OWCs, which may lead to a deterioration of the water quality in NOWC fishponds and lower survival rates. It is thus recommended to reduce the SMR to 31:1 to achieve economies of scale in production and increase the survival rate of milkfish and white shrimp.

Exogenous artificial DNA forms chromatin structure with active transcription in yeast - Jianting Zhou; Chao Zhang; Ran Wei; Mingzhe Han; Songduo Wang; Kaiguang Yang; Lihua Zhang; Weigang Chen; Mingzhang Wen; Cheng Li; Wei Tao; Ying-Jin Yuan (Science China Life Sciences, 2022)
Yeast artificial chromosomes (YACs) are important tools for sequencing, gene cloning, and transferring large quantities of genetic information. However, the structure and activity of YAC chromatin, as well as the unintended impacts of introducing foreign DNA sequences on DNA-associated biochemical events, have not been widely explored. Here, we showed that abundant genetic elements like TATA box and transcription factor-binding motifs occurred unintentionally in a previously reported data-carrying chromosome (dChr). In addition, we used state-of-the-art sequencing technologies to comprehensively profile the genetic, epigenetic, transcriptional, and proteomic characteristics of the exogenous dChr. We found that the data-carrying DNA formed active chromatin with high chromatin accessibility and H3K4 tri-methylation levels. The dChr also displayed highly pervasive transcriptional ability and transcribed hundreds of noncoding RNAs. The results demonstrated that exogenous artificial chromosomes formed chromatin structures and did not remain as naked or loose plasmids. A better understanding of the YAC chromatin nature will improve our ability to design better data-storage chromosomes.

Noninvasive oral cancer screening based on local residual adaptation network using optical coherence tomography - Wei Yuan; Long Cheng; Jinsuo Yang; Boya Yin; Xingyu Fan; Jing Yang; Sen Li; Jianjun Zhong; Xin Huang (Medical & Biological Engineering & Computing, 2022)

Dexmedetomidine post-conditioning alleviates myocardial ischemia–reperfusion injury in rats by ferroptosis inhibition via SLC7A11/GPX4 axis activation - Peng Yu; Jing Zhang; Yi Ding; Dandan Chen; Haijian Sun; Fenglai Yuan; Siyuan Li; Xiaozhong Li; Pingping Yang; Linghua Fu; Shuchun Yu; Jiru Zhang (Human Cell, 2022)

γ-Cyclodextrin metal–organic framework as a carrier to deliver triptolide for the treatment of hepatocellular carcinoma - Zhe Li; Gang Yang; Rong Wang; Yuanyuan Wang; Jing Wang; Meng Yang; Chunai Gong; Yongfang Yuan (Drug Delivery and Translational Research, 2022)

Mechanisms of rockbolt support for highly fractured rock masses–insight from physical and numerical modeling - Hongpu Kang; Jianzhong Li; Guiyang Yuan; Fuqiang Gao; Xiaoqing Wang; Jinghe Yang (Bulletin of Engineering Geology and the Environment, 2022)

Two new dammarane-type triterpenoids from the green walnut husks of Juglans mandshurica Maxim - Yuan-Yuan Zhou; Hui-Rui Gao; Hong-Juan Song; Dan-Da Ma; Xiao-Juan Zhang; Yan-Ping Sun; Yan Liu; Xiao-Li Wang; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Chrysomutanin and related meroterpenoids from a DES mutant of the marine-derived fungus Penicillium chrysogenum S-3-25 - Hua Qiao; Shu-Hua Zhang; Yuan Dong; Yu Yang; Rui Xu; Bo Chen; Yi Wang; Tian-Jiao Zhu; Cheng-Bin Cui; Guo-Gang Zhang; Chang-Wei Li (Natural Product Research, 2022)

Alpha-Lipoic Acid Attenuates MPTP/MPP+-Induced Neurotoxicity: Roles of SIRT1-Dependent PGC-1α Signaling Pathways - Jian Zhang; Ya Gao; Lan Zhang; Cong Zhang; Yuan Zhao; Yidan Zhang; Shuyue Li; Cui Chang; Xiangjian Zhang; Guofeng Yang (Neurotoxicity Research, 2022)

Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats - Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; Bo-Yuan Fan; Ming-Ming Zhang; Tao Chen; Hui Li; Yang Bai; Yun-Qing Li (Neuroscience Bulletin, 2022)
Central sensitization is essential in maintaining chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. Here, we examined the role of the anterior cingulate cortex (ACC) in the pathogenesis of abdominal hyperalgesia in a rat model of CP induced by intraductal administration of trinitrobenzene sulfonic acid (TNBS). TNBS treatment resulted in long-term abdominal hyperalgesia and anxiety in rats. Morphological data indicated that painful CP induced a significant increase in FOS-expressing neurons in the nucleus tractus solitarii (NTS) and ACC, and some FOS-expressing neurons in the NTS projected to the ACC. In addition, a larger portion of ascending fibers from the NTS innervated pyramidal neurons, the neural subpopulation primarily expressing FOS under the condition of painful CP, rather than GABAergic neurons within the ACC. CP rats showed increased expression of vesicular glutamate transporter 1, and increased membrane trafficking and phosphorylation of the N -methyl-D-aspartate receptor (NMDAR) subunit NR2B and the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) subunit GluR1 within the ACC. Microinjection of NMDAR and AMPAR antagonists into the ACC to block excitatory synaptic transmission significantly attenuated abdominal hyperalgesia in CP rats, which was similar to the analgesic effect of endomorphins injected into the ACC. Specifically inhibiting the excitability of ACC pyramidal cells via chemogenetics reduced both hyperalgesia and comorbid anxiety, whereas activating these neurons via optogenetics failed to aggravate hyperalgesia and anxiety in CP rats. Taken together, these findings provide neurocircuit, biochemical, and behavioral evidence for involvement of the ACC in hyperalgesia and anxiety in CP rats, as well as novel insights into the cortical modulation of painful CP, and highlights the ACC as a potential target for neuromodulatory interventions in the treatment of painful CP.

Analysis of studies on environmental measurements using diffusive gradients in thin-films (DGT) from 1994 to 2020 - Tian-Jiao Wei; Dong-Xing Guan; Xi-Yuan Li; Yi-Long Hao; H. Henry Teng; Ji-Feng Yang; Yao-Yang Xu; Gang Li (Journal of Soils and Sediments, 2022)

Indoor air pollution from solid fuel on children pneumonia in low- and middle-income countries: a systematic review and meta-analysis - Tianming Chen; Chao Zou; Yang Yuan; Jingjing Pan; Baoping Zhang; Liang Qiao; Yanping Li; Jia-yan Qian; Qingyuan Guo; Ye Yuan; Cheng Ding (Environmental Science and Pollution Research, 2022)

Analysis on the spatio-temporal evolution and influencing factors of China’s grain production - Shaoting Li; Daojun Zhang; Yuan Xie; Chao Yang (Environmental Science and Pollution Research, 2022)

AT1 Receptors: Their Actions from Hypertension to Cognitive Impairment - Hanxue Wu; Qi Sun; Shenglan Yuan; Jiawei Wang; Fanni Li; Hongli Gao; Xingjuan Chen; Rui Yang; Jiaxi Xu (Cardiovascular Toxicology, 2022)

Factors Influencing Diurnal Variations of Cloud and Precipitation in the Yushu Area of the Tibetan Plateau - Bangjun Cao; Shihua Lyu; Yu Zhang; Xianyu Yang; Boliang Li; Liang Yuan; Meilin Li (Journal of Meteorological Research, 2022)

The Predictability of Ocean Environments that Contributed to the 2020/21 Extreme Cold Events in China: 2020/21 La Niña and 2020 Arctic Sea Ice Loss - Fei Zheng; Ji-Ping Liu; Xiang-Hui Fang; Mi-Rong Song; Chao-Yuan Yang; Yuan Yuan; Ke-Xin Li; Ji Wang; Jiang Zhu (Advances in Atmospheric Sciences, 2022)
Several consecutive extreme cold events impacted China during the first half of winter 2020/21, breaking the low-temperature records in many cities. How to make accurate climate predictions of extreme cold events is still an urgent issue. The synergistic effect of the warm Arctic and cold tropical Pacific has been demonstrated to intensify the intrusions of cold air from polar regions into middle-high latitudes, further influencing the cold conditions in China. However, climate models failed to predict these two ocean environments at expected lead times. Most seasonal climate forecasts only predicted the 2020/21 La Niña after the signal had already become apparent and significantly underestimated the observed Arctic sea ice loss in autumn 2020 with a 1–2 month advancement. In this work, the corresponding physical factors that may help improve the accuracy of seasonal climate predictions are further explored. For the 2020/21 La Niña prediction, through sensitivity experiments involving different atmospheric–oceanic initial conditions, the predominant southeasterly wind anomalies over the equatorial Pacific in spring of 2020 are diagnosed to play an irreplaceable role in triggering this cold event. A reasonable inclusion of atmospheric surface winds into the initialization will help the model predict La Niña development from the early spring of 2020. For predicting the Arctic sea ice loss in autumn 2020, an anomalously cyclonic circulation from the central Arctic Ocean predicted by the model, which swept abnormally hot air over Siberia into the Arctic Ocean, is recognized as an important contributor to successfully predicting the minimum Arctic sea ice extent.

Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra) - Li-Chao Pan; Yang-Yang Sun; Xiao-Ling Zhang; Zhen-Yuan Zhu; Chun-Yu Liu; Hui-Qing Sun; Xue-Qing Geng; Wei Jiang; Jia-He Wang (Natural Product Research, 2022)

Occurrence of structural aluminium (Al) in marine diatom biological silica: visible evidence from microscopic analysis - Qian Tian; Dong Liu; Peng Yuan; Mengyuan Li; Weifeng Yang; Jieyu Zhou; Huihuang Wei; Junming Zhou; Haozhe Guo (Ocean Science, 2022)
The global marine biogeochemical cycle of aluminium (Al) is believed to be driven by marine diatoms, due to the uptake of dissolved Al (DAl) by living diatoms from surface seawater. The occurrence of Al in diatom biogenic silica (BSi) can inhibit the dissolution of BSi, thus benefiting the effects of the ballast role of diatoms in the biological pump and forming a coupled Si–Al biogeochemical cycle. However, the occurrence characteristic of Al in marine diatoms is still unclear. In particular, whether or not Al is incorporated into the structure of BSi of living diatoms is unrevealed, resulting in difficulties in understanding the biogeochemical behaviours of Al. In this study, Thalassiosira weissflogii, a widely distributed marine diatom in marginal seas, was selected as the model to evaluate the occurrence of structural Al in BSi based on culturing experiments with the addition of DAl. The structural Al in BSi was detected by combining focused ion beam (FIB) scanning electron microscopy and energy-dispersive X-ray spectroscopy (EDS) mapping analysis. Visible, direct evidence of structural Al in living BSi was obtained, and the distribution and content of this Al were revealed by the EDS-mapping analysis. The effects of structural Al on BSi dissolution–inhibition are discussed based on the content of this Al. The fundamental results indicate the significant contribution of marine diatoms to the biogeochemical migration of marine Al.

The stress and deformation of stone column-improved soft clay by discrete element modelling - Meixiang Gu; Jie Cui; Jie Yuan; Yang Wu; Yadong Li; Haizhao Mo (European Journal of Environmental and Civil Engineering, 2022)

Fine mapping KT1 on wheat chromosome 5A that conditions kernel dimensions and grain weight - Zhongxin Kong; Ruiru Cheng; Haisheng Yan; Haiyun Yuan; Yong Zhang; Guoqiang Li; Haiyan Jia; Shulin Xue; Wenling Zhai; Yang Yuan; Zhengqiang Ma (Theoretical and Applied Genetics, 2022)

Decreased peripheral mtDNA in methamphetamine use disorder - Ling-Yan Su; Yuan Li; Qianjin Liu; Lijin Jiao; Jing Shen; Lu-Xiu Yang; Ti-Fei Yuan; Yong-Gang Yao (Science China Life Sciences, 2022)

Long non-coding RNA small nucleolar RNA host genes: functions and mechanisms in hepatocellular carcinoma - Yuan Li; Xinxin Wang; Shiyong Chen; Biao Wu; Yu He; Xueqin Du; Xiaojun Yang (Molecular Biology Reports, 2022)

COX-2/PGE2 Pathway Inhibits the Ferroptosis Induced by Cerebral Ischemia Reperfusion - Yunfei Xu; Ying Liu; Kexin Li; Dun Yuan; Shun Yang; Lin Zhou; Yao Zhao; Shuying Miao; Caihong Lv; Jie Zhao (Molecular Neurobiology, 2022)

QTL mapping and candidate gene prediction for fiber yield and quality traits in a high-generation cotton chromosome substitution line with Gossypium barbadense segments - Quanwei Lu; Pengtao Li; Rui Yang; Xianghui Xiao; Ziyin Li; Qiuyu Wu; Juwu Gong; Qun Ge; Aiying Liu; Shengli Du; Jundi Wang; Yuzhen Shi; et al. (Molecular Genetics and Genomics, 2022)

Establishment of Galectin-3 Time-resolved Fluoroimmunoassay and its Application in Idiopathic Membranous Nephropathy - Xiaomei Yu; Lingli Chen; Bo Lin; Li Zhang; Xue Yang; Xiaobin Liu; Pengguo Xia; Yueming Liu; Shaoxiong Zheng; Xiumei Zhou; Yigang Wang; Yuan Qin; et al. (Journal of Fluorescence, 2022)

Circular RNA circ_0008934 promotes hepatocellular carcinoma growth and metastasis through modulating miR-1305/TMTC3 axis - Jia-Xi Li; Jin-Jiang Wang; Zhou-Feng Deng; Hao Zheng; Chun-Mei Yang; Ying Yuan; Cheng Yang; Fang-Fang Gu; Wei-Qi Wu; Guang-Lei Qiao; Li-Jun Ma (Human Cell, 2022)

Reliability Analysis of Reinforced Slope Combining Random Forest Algorithm and Meshless SPH Algorithm - Xu Liu; Liang Li; ShangShang Wang; Fu Chen; Ming Zhai; Zhengquan Yang; Yuan Gao (Geotechnical and Geological Engineering, 2022)

Functional metabolome profiling may improve individual outcomes in colorectal cancer management implementing concepts of predictive, preventive, and personalized medical approach - Yu Yuan; Chenxin Yang; Yingzhi Wang; Mingming Sun; Chenghao Bi; Sitong Sun; Guijiang Sun; Jingpeng Hao; Lingling Li; Changliang Shan; Shuai Zhang; Yubo Li (EPMA Journal, 2022)

Polycyclic aromatic hydrocarbons in street dust from different functional areas in Chengdu, China: seasonal variation and health risk assessment - Han-Han Li; Zhan-Biao Yang; Xiao-Xun Xu; Xue-Mei Zhu; Jun-Ren Xian; Yuan-Xiang Yang; Zhang Cheng (Environmental Geochemistry and Health, 2022)

Analysis of geomorphologic features of the circular structure in the south of Lufeng Dinosaur Valley - Hu Lin; Gan Shu; Yuan Xiping; Yang MingLong; Gao Sha; Bi Rui; Li Yan (Earth Science Informatics, 2022)

Cumulative damage effect on debris slopes under frequent microseisms - Zhong-ping Yang; Shi-qi Li; Xin Tian; Yuan-xin Hu; Wan-kun Li (Journal of Mountain Science, 2022)

Size distributions and dry deposition fluxes of water-soluble inorganic nitrogen in atmospheric aerosols in Xiamen Bay, China - Shui-Ping Wu; Xiang Li; Yang Gao; Mei-Jun Cai; Chao Xu; James J. Schwab; Chung-Shin Yuan (Journal of Atmospheric Chemistry, 2022)

Demersal fish diversity and molecular taxonomy in the Bering Sea and Chukchi Sea - Hai Li; Fang Yang; Xuehua Wang; Yuan Li; Nan Zhang; Ran Zhang; Cheng Liu; Hushun Zhang; Longshan Lin; Puqing Song (Conservation Genetics Resources, 2022)

Intelligent prediction of coal mine water inrush based on optimized SAPSO-ELM model under the influence of multiple factors - Yong-gang Zhang; Yuan-lun Xie; Li-ning Yang; Rao-ping Liao; Tao Qiu (Arabian Journal of Geosciences, 2022)
Mine water inrush is affected by many factors such as geological structure and fracture zone. However, there may be overlap among these factors, leading to uncertainty, fuzzy similarity and nonlinear relationship among most of them. Therefore, the traditional mathematical model is not ideal to predict water inrush. This paper proposes an intelligent model for predicting water inrush from coal floor based on simulated annealing particle swarm optimization-extreme learning machine (SAPSO-ELM). Based on 144 groups of learning data and 36 groups of predictive validation data, the proposed model extracted common factors from 14 geological factors that might be related to water inrush in a mining area, so as to reduce information interaction among discriminant indexes. In this paper, simulated annealing particle swarm optimization (SAPSO) is innovatively used to optimize the model parameters and compared with other intelligent models (SVM, BPNN, PSO-ELM and ELM) for the learning prediction of the same data. The results show that the common factors extracted from the original variables contain most of the comprehensive information and can reduce information redundancy. Compared with traditional intelligent models (SVM, BPNN, PSO-ELM and ELM), the proposed model improves the computational efficiency of convergence, and the prediction accuracy is higher. It is proved that SAPSO-ELM intelligent algorithm is indeed scientific and has broad application prospect in result prediction induced by complex multi-factors.

The antioxidant activities of flavonoids in Jerusalem artichoke ( Helianthus tuberosus L.) leaves and their quantitative analysis - Ming-Yang Wang; Zhi-Li Ma; Cheng-Li He; Xiao-Yan Yuan (Natural Product Research, 2022)

Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice - Na Yang; Xueqin Liu; Xiaojie Niu; Xiaoqiang Wang; Rong Jiang; Na Yuan; Jianrong Wang; Chengwu Zhang; Kah-Leong Lim; Li Lu (Stem Cell Reviews and Reports, 2022)

Cancer metabolism and tumor microenvironment: fostering each other? - Yiyuan Yuan; Huimin Li; Wang Pu; Leilei Chen; Dong Guo; Hongfei Jiang; Bo He; Siyuan Qin; Kui Wang; Na Li; Jingwei Feng; Jing Wen; et al. (Science China Life Sciences, 2022)

Biochanin A Sensitizes Glioblastoma to Temozolomide by Inhibiting Autophagy - Qiang Dong; Degui Wang; Lanlan Li; Jie Wang; Qiao Li; Lei Duan; Hang Yin; Xiaoqing Wang; Yang Liu; Guoqiang Yuan; Yawen Pan (Molecular Neurobiology, 2022)

Allelically and Differentially Expressed Genes After Infection of Edwardsiella ictaluri in Channel Catfish as Determined by Bulk Segregant RNA-Seq - Yulin Jin; Tao Zhou; Wansheng Jiang; Ning Li; Xiaoyan Xu; Suxu Tan; Huitong Shi; Yujia Yang; Zihao Yuan; Wenwen Wang; Guyu Qin; Shikai Liu; et al. (Marine Biotechnology, 2022)

GNG12 Targeted by miR-876-5p Contributes to Glioma Progression Through the Activation of the PI3K/AKT Signaling Pathway - Ling Li; Qiuying Zhang; Leyong Yuan; Yanlong Yang; Xiaobo Wang; Fangfang Liu; Yang Liu; Mingshui Xie (Journal of Molecular Neuroscience, 2022)

Does income inequality aggravate the impacts of air pollution on physical health? Evidence from China - Zhiming Yang; Zhen Wang; Xiao-Chen Yuan; Yu Qi; Yunquan Zhang; Weiqing Wang; Fanglin He; Jing Li (Environment, Development and Sustainability, 2022)

Transcriptome Analysis Reveals Molecular Mechanisms Underlying Methyl Jasmonate-mediated Biosynthesis of Protopanaxadiol-type Saponins in Panax notoginseng Leaves - Ying Li; Yuan Lin; Bing Jia; Geng Chen; Huineng Shi; Rui Xu; Xuejiao Li; Junrong Tang; Qingyan Tang; Guanghui Zhang; Jianli Yang; Wei Fan; et al. (Journal of Plant Biology, 2022)

Identification of Isthmin1 in the small annual fish, Nothobranchius guentheri, as a novel biomarker of aging and its potential rejuvenation activity - Congjun Li; Lili Song; Yang Zhou; Jiangshui Yuan; Shicui Zhang (Biogerontology, 2022)

miR-122 Inhibits the Cervical Cancer Development by Targeting the Oncogene RAD21 - Yanling Yang; Yang Liu; Wei Liu; Chunyang Li; Yuan Liu; Wenyang Hu; Hongjuan Song (Biochemical Genetics, 2022)

Annual Lateral Organic Carbon Exchange Between Salt Marsh and Adjacent Water: A Case Study of East Headland Marshes at the Yangtze Estuary - Yiquan Yuan; Xiuzhen Li; Zuolun Xie; Liming Xue; Bin Yang; Wenzhen Zhao; Christopher B. Craft (Frontiers in Marine Science, 2022)
Blue carbon (C) ecosystems (mangroves, salt marshes, and seagrass beds) sequester high amounts of C, which can be respired back into the atmosphere, buried for long periods, or exported to adjacent ecosystems by tides. The lateral exchange of C between a salt marsh and adjacent water is a key factor that determines whether a salt marsh is a C source (i.e., outwelling) or sink in an estuary. We measured salinity, particulate organic carbon (POC), and dissolved organic carbon (DOC) seasonally over eight tidal cycles in a tidal creek at the Chongming Dongtan wetland from July 2017 to April 2018 to determine whether the marsh was a source or sink for estuarine C. POC and DOC fluxes were significantly correlated in the four seasons driven by water fluxes, but the concentration of DOC and POC were positively correlated only in autumn and winter. DOC and POC concentrations were the highest in autumn (3.54 mg/L and 4.19 mg/L, respectively) and the lowest in winter and spring (1.87 mg/L and 1.51 mg/L, respectively). The tidal creek system in different seasons showed organic carbon (OC) export, and the organic carbon fluxes during tidal cycles ranged from –12.65 to 4.04 g C/m 2 . The intensity showed significant seasonal differences, with the highest in summer, the second in autumn, and the lowest in spring. In different seasons, organic carbon fluxes during spring tides were significantly higher than that during neap tides. Due to the tidal asymmetry of the Yangtze River estuary and the relatively young stage, the salt marshes in the study area acted as a strong lateral carbon source.

Secondary metabolites isolated from Agrimonia pilosa Ledeb. - Hong-Rui Li; Yu-Kui Li; Jian Xiao; Cui Yang; Meng-Yuan Jiang; Kai Tian; Wei Wang; Yan-Hong Li; Xiang-Zhong Huang (Natural Product Research, 2022)

Myrothecol A, a new alkylresorcinol with cytotoxicity from Myrothecium sp. - Zhen-Hua Li; Hui-Yuan Yang; Wen-Ting Zhu; Dong-Dong Jing; Shi-Neng Li; Peng-Ke Yan (Natural Product Research, 2022)

Cloning and expression analysis of the HSL gene in Whitmania pigra (Annelida: Hirudinea) - Li-Yuan Guo; Qiao-Sheng Guo; Hong-Zhuan Shi; Feng Yang; Yi-Xiu Miao (Invertebrate Reproduction & Development, 2022)

The genomic history of southwestern Chinese populations demonstrated massive population migration and admixture among proto-Hmong–Mien speakers and incoming migrants - Yicheng Wang; Xing Zou; Mengge Wang; Didi Yuan; Li Yang; Yujie Zeng; Fang Cheng; Renkuan Tang; Guanglin He (Molecular Genetics and Genomics, 2022)

Circular RNA screening identifies circMYLK4 as a regulator of fast/slow myofibers in porcine skeletal muscles - Haigang Cao; Jieming Liu; Tianning Du; Yihao Liu; Xiaoyu Zhang; Yuan Guo; Jie Wang; Xiaomin Zhou; Xiao Li; Gongshe Yang; Xin’e Shi (Molecular Genetics and Genomics, 2022)
The type of myofiber is related to the quality of meat. The slow oxidized myofiber helps to increase the tenderness and juiciness of muscle. Numerous studies have shown that circRNA plays a key role in skeletal muscle development. However, the role of circRNA in porcine skeletal myofiber types is unclear. In this study, we performed high-throughput RNA sequencing to study the differential expression of circRNA in the longissimus dorsi and the soleus muscle. A total of 40,757 circRNAs were identified, of which 181 were significantly different. Interestingly, some circRNAs were involved in metabolism pathways, AMPK, FoxO, and PI3K-Akt signaling pathways. Besides, we focused on a novel circRNA-circMYLK4. By injecting circMYLK4-AAV into piglets, we found that circMYLK4 significantly increased the mRNA and protein levels of the slow muscle marker genes. In summary, our study laid an essential foundation for further research of circRNA in myofiber type conversion and higher meat quality.

A community effort to assess and improve computerized interpretation of 12-lead resting electrocardiogram - Zijian Ding; Guijin Wang; Huazhong Yang; Ping Zhang; Dapeng Fu; Zhen Yang; Xinkang Wang; Xia Wang; Zhourui Xia; Chiming Zhang; Wenjie Cai; Binhang Yuan; et al. (Medical & Biological Engineering & Computing, 2022)
Computerized interpretation of electrocardiogram plays an important role in daily cardiovascular healthcare. However, inaccurate interpretations lead to misdiagnoses and delay proper treatments. In this work, we built a high-quality Chinese 12-lead resting electrocardiogram dataset with 15,357 records, and called for a community effort to improve the performances of CIE through the China ECG AI Contest 2019. This dataset covers most types of ECG interpretations, including the normal type, 8 common abnormal types, and the other type which includes both uncommon abnormal and noise signals. Based on the Contest, we systematically assessed and analyzed a set of top-performing methods, most of which are deep neural networks, with both their commonalities and characteristics. This study establishes the benchmarks for computerized interpretation of 12-lead resting electrocardiogram and provides insights for the development of new methods.

Dietary Calcium Alleviates Fluorine-Induced Liver Injury in Rats by Mitochondrial Apoptosis Pathway - Haojie Li; Zijun Hao; Li Wang; Jiarong Yang; Yangfei Zhao; Xiaofang Cheng; Haiyan Yuan; Jinming Wang (Biological Trace Element Research, 2022)

The effects of immersive garden experience on the health care to elderly residents with mild-to-moderate cognitive impairment living in nursing homes after the COVID-19 pandemic - Chung-Heng Hsieh; Cheng-Min Chen; Ju-Yuan Yang; Yen-Ju Lin; Man-Li Liao; Ke-Hsin Chueh (Landscape and Ecological Engineering, 2022)

Analysis of Timing Effect on Flow Field and Pulsation in Vertical Axial Flow Pump - Fan Yang; Pengcheng Chang; Yao Yuan; Na Li; Rongsheng Xie; Xiaowen Zhang; Zhikang Lin (Journal of Marine Science and Engineering, 2021)
Vertical axial flow pump device has the characteristics of large flow and low head, which is widely used in pumping station projects with head of 3–9 m. In order to study the influence of the timing effect of the impeller relative flow channel and guide vane on the flow field and pulsation in the axial flow pump device, the whole flow channel of the vertical axial flow pump device was taken as the research object. The reliability of the numerical simulation was verified by physical model test. The flow field characteristics and pressure pulsation characteristics of the inlet and outlet regions of the impeller, the guide vane and the campaniform inlet conduit at different timing positions of the impeller under different flow rates were analyzed. The results show that the pressure coefficient distribution of the impeller inlet of the vertical axial flow pump device presents four high-pressure areas and four low-pressure areas with the rotation of the impeller. The pressure pulsation at the inlet and outlet of the impeller is mainly affected by the rotation of the impeller, and the main frequency is 4 times the rotation frequency amplitude of pressure pulsation decreases with the increase of flow rate. When the flow rate increased from 0.8 Qbep to 1.2 Qbep, the average velocity circulation at the guide vane outlet decreased by 12%; there is an obvious negative value region of the internal regularized helicity of the guide vane. When the flow rate increases from 0.8 Qbep to 1.2 Qbep, the amplitude of the pressure pulsation coefficient at the outlet of the guide vane decreases gradually, with a decrease of 94%. When the flow rate is 1.2 Qbep, the main frequency and the secondary frequency of the pressure pulsation are both low-frequency, with obvious low-frequency pulsation characteristics. Under the small flow condition of 0.8 Qbep, the outlet flow fluctuation of seven guide vane was 18.9% on average, and the flow variation of each guide vane was large. Under the optimal flow condition of 1.0 Qbep and large flow condition of 1.2 Qbep, the outlet flow fluctuation of 7 guide vane is 4.7% and 0.56% on average, and the flow change of each guide vane is stable. The outlet flow of the guide vane is mainly concentrated in two guide vane slots of the guide vane, and the flow ratios are 30.56%, 30.14% and 29.16% under three flow conditions, respectively. The research results provide a scientific basis for the optimization design and stable operation of vertical axial flow pump device.

Comparative Transcriptome Analysis of Female and Male Fine-Patterned Puffer: Identification of Candidate Genes Associated with Growth and Sex Differentiation - Binbin Shan; Yan Liu; Changping Yang; Yuan Li; Liangming Wang; Dianrong Sun (Fishes, 2021)
Sexual growth dimorphism is a common phenomenon in teleost fish. However, the mechanism of this complex phenomenon remains unclear. The fine-patterned puffer (Takifugu poecilonotus; Temminck and Schlegel, 1850) exhibits female-biased sexual size dimorphism similar to other pufferfish. In this study, the transcriptomes of female and male T.poecilonotus were sequenced, 285.95 million raw read pairs were generated from sequence libraries. After identification and assembly, a total of 149,814 nonredundant unigenes were obtained with an N50 length of 3538 bp. Of these candidates, 122,719 unigenes (81.91% of the total) were successfully annotated with multiple public databases. The comparison analysis revealed 10,385 unigenes (2034 in females and 8351 in males) were differentially expressed between different sexes of T.poecilonotus. Then, we identified many candidate growth- and sex-related genes, including Dmrt1, Sox3, Spatas, Prl/Prlr, fabps, Ghr, and Igf1r. In addition to these well-known genes, Fabp4 was identified for the first time in fish. Furthermore, 68,281 simple sequence repeats (SSRs) loci were screened and identified in the transcriptome sequence of T.poecilonotus. The results of our study could provide valuable information on growth- and sex-associated genes and facilitate further exploration of the molecular mechanism of sexual growth dimorphism.

Investigation of factors influencing the release of chloropropanols (3-MCPD and 1,3-DCP) from food contact paper - Huai-ning Zhong; Ying Zeng; Dao-yuan Yang; Ze-chun Wu; Dan Li; Hai-xia Sui; Jie Gao; Yan-fen Chen; Ce-Hui Mo (Food Additives & Contaminants: Part A, 2021)

Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology - Yuhong Zhang; Xu Chen; Qiqi Wang; Congcong Du; Wenbin Lu; Hong Yuan; Zhenzhen Zhang; Danqing Li; Xing Ling; Xiang Ren; Yang Zhao; Qi Su; et al. (Journal of Molecular Medicine, 2021)

Correction to: Synthesis and evaluation of iridium(III) complexes on antineoplastic activity against human gastric carcinoma SGC‑7901 cells - Li Tian; Yuanyuan Zhang; Huiwen Zhang; Yi Zhou; Wenlong Li; Yuhan Yuan; Jing Hao; Linlin Yang; Yunjun Liu (JBIC Journal of Biological Inorganic Chemistry, 2021)

Correction to: Enhanced adsorption of phosphorus in soil by lanthanum-modified biochar: improving phosphorus retention and storage capacity - Di Zhao; Yuan Luo; Yi-yang Feng; Qiu-ping He; Li-sheng Zhang; Ke-qiang Zhang; Feng Wang (Environmental Science and Pollution Research, 2021)

Enhanced adsorption of phosphorus in soil by lanthanum-modified biochar: improving phosphorus retention and storage capacity - Di Zhao; Yuan Luo; Yi-yang Feng; Qiu-ping He; Li-sheng Zhang; Ke-qiang Zhang; Feng Wang (Environmental Science and Pollution Research, 2021)

A Fuzzy Analytical Process to Assess the Risk of Disaster when Backfill Mining Under Aquifers and Buildings - Jiawei Liu; Binbin Yang; Shichong Yuan; Zhiheng Li; Mingfei Yang; Lihong Duan (Mine Water and the Environment, 2021)

The Common Occurrence of Theileria ovis in Tibetan Sheep and the First Report of Theileria sinensis in Yaks from Southern Qinghai, China - Ye Wang; Bo Wang; Qingxun Zhang; Ying Li; Ziwen Yang; Shuyi Han; Guohui Yuan; Shuangling Wang; Hongxuan He (Acta Parasitologica, 2021)

Antibiotic intervention redisposes bacterial interspecific interacting dynamics in competitive environments - Jing Li; Xiaojie Chen; Jiafu Lin; Yang Yuan; Ting Huang; Lianming Du; Balakrishnan Prithiviraj; Aixue Zhang; Xinrong Wang; Yiwen Chu; Kelei Zhao (Environmental Microbiology, 2021)
Summary Interspecific interaction happens frequently among bacterial species and can promote the colonization of polymicrobial community in various environments. However, it is not clear whether the intervention of antibiotics, which is a common therapeutic method for infectious disease, will influence the interacting dynamics of different pathogenic bacteria. By using the frequently co‐isolated bacteria Pseudomonas aeruginosa and Staphylococcus aureus as models, here we identify an antibiotic‐determined mutual invasion relationship between bacterial pathogens. We show that although P . aeruginosa has a significant intrinsic competitive advantage over S . aureus by producing the quorum‐sensing (QS)‐controlled anti‐staphylococcal molecules, methicillin‐resistant S . aureus (MRSA) can inhibit neighbouring P . aeruginosa in the presence of subinhibitory aminoglycoside antibiotics (e.g. streptomycin) to P . aeruginosa . Importantly, subinhibitory streptomycin decreases the expression of QS‐regulated genes in P . aeruginosa and thus relieves the survival stress of MRSA brought by P . aeruginosa . On the other side, the iron‐uptake systems and pathogenicity of MRSA can be enhanced by the extracellular products of streptomycin‐treated P . aeruginosa . Therefore, this study provides an explanation for the substitution of dominant species and persistent coexistence of bacterial pathogens in the host with repeated antibiotic therapies and contributes to further understanding the pathogenesis of chronic polymicrobial infections.

Trapping of Microplastics in Halocline and Turbidity Layers of the Semi-enclosed Baltic Sea - Qian Zhou; Chen Tu; Jie Yang; Chuancheng Fu; Yuan Li; Joanna J. Waniek (Frontiers in Marine Science, 2021)
Microplastic pollution in semi-enclosed seas is gaining attention since microplastics are more likely to accumulate there. However, research on the vertical distribution of microplastics and impact factors is still limited. In this study, we focus on the Baltic Sea, which has distinguished salinity stratification, and we assume that the resulting strong density stratification (halocline) can influence the vertical distribution of microplastics in the water column. Therefore, we analyzed the vertical abundance distribution, the composition, and the sizes of microplastics (27.3–5,000.0 μm) in the Baltic Sea. The results showed that microplastics comprising fibers, fragments, and films occurred throughout the water column at an abundance of 1.1–27.7 items L −1 . The abundance of microplastics (3.2–27.7 items L −1 ) at haloclines was significantly higher than those at other water depths except the near surfaces ( p < 0.05), contributing 24.1–53.2% of the microplastics in the whole water column. Small microplastics (<100 μm) were more likely to accumulate in the water layers above halocline. Moreover, the current with high turbidity might be another carrier of microplastics in the near-bottom water layer due to its strong correlation with microplastics abundance. This study provides valuable evidence for the accumulation trend of microplastics in water columns and its influencing factors in the semi-enclosed marginal sea. Further research on the vertical distribution of microplastics under the control of multiple factors should be conducted in the future.

Three new cycloart-7-ene triterpenoid glycosides from Cimicifuga dahurica and their anti-inflammatory effects - Qian-Qian Pang; Yu-Dan Mei; Yuan-Chu Zhang; Ling-Xian Liu; Dan-Feng Shi; Da-Bo Pan; Xin-Sheng Yao; Hai-Bo Li; Yang Yu (Natural Product Research, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Comparison of nitrogen removal efficiency and microbial characteristics of modified two-stage A/O, A2/O and SBR processes - Xiurong Chen; Xiao Wei; Yingying Yang; Shanshan Wang; Quanlin Lu; Yuan Wang; Qiuyue Li; Shuoyuan Wang (Environmental Geochemistry and Health, 2021)

Nitrogen addition amplifies the nonlinear drought response of grassland productivity to extended growing‐season droughts - Bo Meng; Junqin Li; Gregory E. Maurer; Shangzhi Zhong; Yuan Yao; Xuechen Yang; Scott L. Collins; Wei Sun (Ecology, 2021)
Understanding the response of grassland production and carbon exchange to intra‐annual variation in precipitation and nitrogen addition is critical for sustainable grassland management and ecosystem restoration. We introduced growing‐season drought treatments of different lengths (15, 30, 45 and 60 d drought) by delaying growing‐season precipitation in a long‐term nitrogen addition experiment in a low diversity meadow steppe in northeast China. Response variables included aboveground biomass (AGB), ecosystem net carbon exchange (NEE), and leaf net carbon assimilation rate ( A ). In unfertilized plots drought decreased AGB by 13.7% after a 45‐d drought and 31.7% after a 60‐d drought (47.6% in fertilized plots). Progressive increases in the drought response of NEE were also observed. The effects of N addition on the drought response of productivity increased as drought duration increased, and these responses were a function of changes in AGB and biomass allocation, particularly root to shoot ratio. However, no significant effects of drought occurred in fertilized or unfertilized plots in the growing season a year after the experiment, N addition did limit the recovery of AGB from severe drought during the remainder of the current growing season. Our results imply that chronic N enrichment could exacerbate the effects of growing‐season drought on grassland productivity caused by altered precipitation seasonality under climate change, but that these effects do not carry over to the next growing season.

The Relationship Between the Gut Microbiome and Neurodegenerative Diseases - Xueling Zhu; Bo Li; Pengcheng Lou; Tingting Dai; Yang Chen; Aoxiang Zhuge; Yin Yuan; Lanjuan Li (Neuroscience Bulletin, 2021)
Many recent studies have shown that the gut microbiome plays important roles in human physiology and pathology. Also, microbiome-based therapies have been used to improve health status and treat diseases. In addition, aging and neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, have become topics of intense interest in biomedical research. Several researchers have explored the links between these topics to study the potential pathogenic or therapeutic effects of intestinal microbiota in disease. But the exact relationship between neurodegenerative diseases and gut microbiota remains unclear. As technology advances, new techniques for studying the microbiome will be developed and refined, and the relationship between diseases and gut microbiota will be revealed. This article summarizes the known interactions between the gut microbiome and neurodegenerative diseases, highlighting assay techniques for the gut microbiome, and we also discuss the potential therapeutic role of microbiome-based therapies in diseases.

Availability and diffusion kinetic process of phosphorus in the water–sediment interface assessed by the high-resolution DGT technique - Yanwen Zhou; Haixiang Wang; Yinlong Zhang; Yiwei Cai; Hongbin Yin; Zhen Yang; Qiang Li; Hezhong Yuan (Journal of Soils and Sediments, 2021)

Quantitative assessment of rockfall hazard in post-landslide high rock slope through terrestrial laser scanning - Jie-yuan Zhang; Hai-bo Li; Xing-guo Yang; Nan Jiang; Jia-wen Zhou (Bulletin of Engineering Geology and the Environment, 2021)

Impulsivity in heroin‐dependent individuals: structural and functional abnormalities within frontostriatal circuits - Shicong Wang; Min Zhang; Shuang Liu; Yan Xu; Ziqiang Shao; Longmao Chen; Jun Li; Wenhan Yang; Jun Liu; Kai Yuan (Brain Imaging and Behavior, 2021)

The influence of light intensity and organic content on cultivation of Chlorella vulgaris in sludge extracts diluted with BG11 - Xiurong Chen; Yingying Yang; Quanling Lu; Xiaoli Sun; Shanshan Wang; Qiuyue Li; Xiao Wei; Yuan Wang (Aquaculture International, 2021)

Cross‐phytogroup assessment of foliar epiphytic mycobiomes - Ting Zhu; Jia Yao; Hao Liu; Chen‐Hao Zhou; Yuan‐Zhan Liu; Zheng‐Wei Wang; Zhe‐Xue Quan; Bo Li; Ji Yang; Wei‐Chang Huang; Ming Nie (Environmental Microbiology, 2021)
Summary The foliar surface forms one of the largest aboveground habitats on Earth and maintains plant‐fungus relationships that greatly affect ecosystem functioning. Despite many studies with particular plant species, the foliar epiphytic mycobiome has not been studied across a large number of plant species from different taxa. Using high‐throughput sequencing, we assessed epiphytic mycobiomes on leaf surfaces of 592 plant species in a botanical garden. Plants of angiosperms, gymnosperms, and pteridophytes were involved. Plant taxonomy, leaf side, growing environment, and evolutionary relationships were considered. We found that pteridophytes showed the higher fungal species diversity, stronger mutualistic fungal interactions, and a greater percentage of putative pathogens than gymnosperms and angiosperms. Plant taxonomic group, leaf side, and growing environment were significantly associated with the foliar epiphytic mycobiome, but the similarity of the mycobiomes among plants was not directly related to the distance of the host evolutionary tree. Our results provide a general understanding of the foliar fungal mycobiomes from pteridophytes to angiosperms. These findings will facilitate our understanding of foliar fungal epiphytes and their roles in plant communities and ecosystems.

Stock Assessment of Hatchery-Released Clam Meretrix meretrix in an Estuary of China From the Perspectives of Population Ecology and Genetic Diversity - Anguo Zhang; Hongjun Li; Xiaolong Yang; Lili Wang; Yangchun Gao; Mingshan Song; Xiutang Yuan (Frontiers in Marine Science, 2021)
In this study, the release effects of the buried clam Meretrix meretrix in a northern estuary of China (Shuangtaizi Estuary) was assessed in terms of population ecology and genetic variability by using longer-term monitoring data from 2011 (used as the baseline data) to 2018. A total of 2.4 × 10 8 hatchery juveniles were released from 2012 to 2014, and follow-up monitoring survey of the growth, distribution, density, and biomass of M. meretrix population was carried out. Results showed a temporary spike in the population of M. meretrix , and the population underwent considerable year-to-year fluctuations in total abundance and biomass. Meanwhile, the age structure of the populations from 2011 to 2018 is still an unstable expanding type. Genetic analysis based on 10 polymorphic microsatellite markers revealed no significant genetic differentiation and weak genetic structures between years but higher genetic diversities in 2014–2018 than in the initial period (2013) of stock restoration. Our study suggests that effective policies for management and conservation to restore M. meretrix population by local governments are still needed in the long run.

Genetic control of Fusarium head blight resistance in two Yangmai 158-derived recombinant inbred line populations - Haisheng Yan; Guoqiang Li; Jinxing Shi; ShunShun Tian; Xiaoqiu Zhang; Rui Cheng; Xin Wang; Yang Yuan; Shouyang Cao; Jiyang Zhou; Zhongxin Kong; Haiyan Jia; et al. (Theoretical and Applied Genetics, 2021)

Problem-solving deficits in methcathinone use disorder - Hang-Bin Zhang; Di Zhao; Yu-Ping Liu; Li-Xun Wang; Bo Yang; Ti-Fei Yuan (Psychopharmacology, 2021)

Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia - Jing Guo; Xiao-Li-Na Zhang; Zhang-Rui Bao; Xue-Ke Yang; Ling-Shuang Li; Yu Zi; Fan Li; Chun-Yun Wu; Juan-Juan Li; Yun Yuan (NeuroMolecular Medicine, 2021)

Effects of long-term fasting and confinement on the cardiovascular activity - Yang Liu; Qince Li; Kuanquan Wang; Runnan He; Zhongquan Dai; Hongyu Zhang; Chengyu Liu; Qianying Ma; Yongfeng Yuan; Chengjia Yang; Yinghui Li; Henggui Zhang (Medical & Biological Engineering & Computing, 2021)

Synthesis and evaluation of iridium(III) complexes on antineoplastic activity against human gastric carcinoma SGC-7901 cells - Li Tian; Yuanyuan Zhang; Huiwen Zhang; Yi Zhou; Wenlong Li; Yuhan Yuan; Jing Hao; Linlin Yang; Yunjun Liu (JBIC Journal of Biological Inorganic Chemistry, 2021)

Profiling heterogenous sizes of circulating tumor microemboli to track therapeutic resistance and prognosis in advanced gastric cancer - Yang Chen; Jiajia Yuan; Yanyan Li; Xue Li; Ying Yang; Jian Li; Yilin Li; Lin Shen (Human Cell, 2021)
Circulating tumor microemboli (CTM) aggregated by ≥ 2 circulating tumor cells (CTCs) are more migratory than single CTCs. Aside from the plasticity in their molecular characteristics, which have been considered tumor migration, CTM also possesses high size heterogeneity. This study, therefore, systematically investigated the heterogeneous sizes of CTM and their involvement in therapeutic resistance in 114 patients with advanced gastric cancer (GC) using a pre-established surface molecule-independent subtraction enrichment (SE)-iFISH strategy. CTM, which was pre-therapeutically detected in 33.3% of GC patients, can further form in another 34.78% of patients following chemo-/targeted therapies. The presence of CTM is relevant to liver metastasis as well as higher CTC levels (≥ 5/6 mL). Further size-based profiling of GC-CTM revealed that CTM with 2 CTCs (CTM 2 ) was the dominant subtype, accounting for 50.0% of all detected GC-CTMs. However, CTM with 3–4 CTCs (CTM 3–4 ) specifically associates with chemo-/targeted therapeutic resistance and inferior prognosis. Patients with ≥ 1 CTM 3–4 /6 mL have shorter median progression-free survival and median overall survival. Unlike CTM 2 and CTM 3–4 , which are detectable in pre-therapy and post-therapy, larger aggregated CTM ≥5 (CTM with ≥ 5 CTCs) was only intra-therapeutically detected in four HER2 + GC patients, of which three experienced liver metastases. Obtained results suggested that the cluster size of GC-CTM should be dynamically profiled beyond pre-therapeutic whole CTM enumeration in terms of chemo-/targeted resistance or metastasis monitoring. GC-CTM 3–4 could be a potential indicator of therapeutic resistance, while the dynamic presence of GC-CTM ≥5 implies liver metastasis in HER2 + GC patients.

The effects of biochar/compost for adsorption behaviors of sulfamethoxazole in amended wetland soil - Siqun Tang; Jie Liang; Jilai Gong; Biao Song; Zhaoxue Yang; Siyuan Fang; Peng Zhang; Weicheng Cao; Juan Li; Yuan Luo (Environmental Science and Pollution Research, 2021)

Enhanced β-carotene production by overexpressing the DID2 gene, a subunit of ESCRT complex, in engineered Yarrowia lipolytica - Fan Yang; Liang Liu; Shan Qiang; Ching Yuan Hu; Ying Li; Yong Hong Meng (Biotechnology Letters, 2021)

An improved convolution perfectly matched layer for elastic second-order wave equation - Ling-Yun Yang; Guo-Chen Wu; Qing-Yang Li; Zhan-Yuan Liang (Applied Geophysics, 2021)

Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration - Jinyan Wu; Quyang Yang; Sainan Wu; Ruoyue Yuan; Xiansheng Zhao; Yue Li; Wenyu Wu; Ningwen Zhu (Tissue Engineering and Regenerative Medicine, 2021)

Effects of dietary whole and defatted Arthrospira platensis (Cyanobacterium) on growth, body composition and pigmentation of the yellow catfish Pelteobagrus fulvidraco - Cui Liu; Yanhua Li; Zheng Chen; Li Yuan; Haokun Liu; Dong Han; Junyan Jin; Yunxia Yang; Qiang Hu; Xiaoming Zhu; Shouqi Xie (Journal of Applied Phycology, 2021)

Size distributions and health risks of particle-bound toxic elements in the southeast coastland of China - Shui-Ping Wu; Xiang Li; Mei-Jun Cai; Yang Gao; Chao Xu; James J. Schwab; Chung-Shin Yuan (Environmental Science and Pollution Research, 2021)

Rock Types and Reservoir Characteristics of Shahejie Formation Marl in Shulu Sag, Jizhong Depression, Bohai Bay Basin - Jingwei Cui; Xuanjun Yuan; Songtao Wu; Ruifeng Zhang; Song Jin; Yang Li (Journal of Earth Science, 2021)

Fluid Mobility Evaluation of Tight Sandstones in Chang 7 Member of Yanchang Formation, Ordos Basin - Songtao Wu; Shixiang Li; Xuanjun Yuan; Zhi Yang; Aifen Li; Jingwei Cui; Songqi Pan; Zhiguo Mao; Ling Su; You Zhou (Journal of Earth Science, 2021)

Physicochemical Characterization and Biopharmaceutical Evaluation of ZWF: A Novel Anticancer Drug for the Treatment of Non-small Cell Lung Cancer - Lina Zhao; Li He; Yuan Chen; Tongchao Xia; Le Li; Shengyan Wang; Xu Bao; Junyi Yang (AAPS PharmSciTech, 2021)

Effects of continuous cucumber cropping on crop quality and soil fungal community - Kaining Sun; Longyun Fu; Yang Song; Liang Yuan; Haoran Zhang; Dan Wen; Ning Yang; Xiao Wang; Yaoquan Yue; Xuhua Li; Kean Wang (Environmental Monitoring and Assessment, 2021)

Experimental Study of O2-Enriched CO2 Production by BaCo0.8B0.2O3−δ (B=Ce, Al, Fe, Cu) Perovskites Sorbent for Marine Exhaust CO2 Capture Application - Qiuwan Shen; Zicheng Shao; Shian Li; Guogang Yang; Jinliang Yuan; Xinxiang Pan (Journal of Marine Science and Engineering, 2021)
An effective approach for reducing CO2 emissions from marine exhaust is adopting oxyfuel combustion technology. A series of B-site doped BaCo0.8B0.2O3−δ (B=Ce, Al, Fe, Cu) perovskites as novel oxygen carrier applications were prepared by the sol-gel method. The oxygen desorption characteristics of the B-site doped BaCo0.8B0.2O3−δ perovskites and the effects of adsorption/desorption temperature, CO2 volume flow rate, CO2 partial pressures, and adsorption time were researched in the fixed bed reactor. The surface morphology and size of the oxygen carrier was observed by scanning electron microscope (SEM). Results showed that BaCo0.8Al0.2O3−δ and BaCo0.8Ce0.2O3−δ have comparable performance, considering the cost of the raw materials. BaCo0.8Al0.2O3−δ was selected as candidate for further study. The optimal adsorption/desorption temperature, CO2 volume flow rate, CO2 partial pressure and adsorption time for BaCo0.8Al0.2O3−δ were studied in detail. Results showed that the best operating parameters were determined to be 850 °C/850 °C for adsorption/desorption temperature, 200 mL/min for CO2 volume flow rate, 100% CO2 partial pressure, and 30 min for absorption time, respectively. Furthermore, multiple cycle results indicate that BaCo0.8Al0.2O3−δ sorbent has high reactivity and cyclic stability.

Population origin, maternal effects, and hydric conditions during incubation determine embryonic and offspring survival in a desert-dwelling lizard - Yang Wang; Shu-Ran Li; Meng-Yuan Pei; Dan-Yang Wu; Wei-Guo Du (Oecologia, 2021)

Different posterior hippocampus and default mode network modulation in young APOE ε4 carriers: a functional connectome-informed phenotype longitudinal study - Li Juan Zheng; Li Lin; U. Joseph Schoepf; Akos Varga-Szemes; Rock H. Savage; Han Zhang; Yun Fei Wang; Xin Yuan Zhang; Song Luo; Ya Liu; Gui Fen Yang; Guang Ming Lu; et al. (Molecular Neurobiology, 2021)

TNFAIP1 Is Upregulated in APP/PS1 Mice and Promotes Apoptosis in SH-SY5Y Cells by Binding to RhoB - Ye Xiao; Yadan Li; Huihui Zhang; Liping Yang; Yinghua Jiang; Chenxi Wei; Xing Feng; Yu Xun; Shishan Yuan; Shuanglin Xiang; Ning Liu (Journal of Molecular Neuroscience, 2021)

Runx2 deficiency in junctional epithelium of mouse molars decreases the expressions of E-cadherin and junctional adhesion molecule 1 - Yuan Tian; Haiyu Mu; Aiqin Wang; Yan Gao; Zhiheng Dong; Yang Zhao; Cong Li; Li Zhang; Yuguang Gao (Journal of Molecular Histology, 2021)

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

New insights into the fine-scale history of western–eastern admixture of the northwestern Chinese population in the Hexi Corridor via genome-wide genetic legacy - Hongbin Yao; Mengge Wang; Xing Zou; Yingxiang Li; Xiaomin Yang; Ailin Li; Hui-Yuan Yeh; Peixin Wang; Zheng Wang; Jingya Bai; Jianxin Guo; Jinwen Chen; et al. (Molecular Genetics and Genomics, 2021)

Development of a pyrF-based counterselectable system for targeted gene deletion in Streptomyces rimosus - Yiying Yang; Qingqing Sun; Yang Liu; Hanzhi Yin; Wenping Yang; Yang Wang; Ying Liu; Yuxian Li; Shen Pang; Wenxi Liu; Qian Zhang; Fang Yuan; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

The objects, agents, and tools of Chinese co-governance on air pollution: a review - Zhaopeng Li; Xiaoling Yuan; Jihong Xi; Li Yang (Environmental Science and Pollution Research, 2021)

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

Arbuscular mycorrhizal fungus-induced decrease in nitrogen concentration in pore water and nitrogen leaching loss from red soil under simulated heavy rainfall - Yongmei He; Bo Li; Kai Yan; Rui Yang; Gang Lei; Mingrui Li; Yuan Li; Fangdong Zhan (Environmental Science and Pollution Research, 2021)

Carbon-based membrane materials and applications in water and wastewater treatment: a review - Chen Li; Jie Yang; Luying Zhang; Shibo Li; Yin Yuan; Xin Xiao; Xinfei Fan; Chengwen Song (Environmental Chemistry Letters, 2021)

Effects of habitat fragmentation on the demography of the critically endangered tree Pterospermum kingtungense (Sterculiaceae) in Yunnan, China - Chun-Ming Yuan; Shan-Shan Zhang; Guo-Ping Yang; Jian Chen; Yun-Fen Geng; Xiao-Shuang Li; Wen-Zhong Yang (Tropical Ecology, 2021)

Reclassification of Algibacter wandonensis as a Later Heterotypic Synonym of Algibacter lectus Based on Whole-Genome Sequence Analysis - Ang Liu; Hui Wang; Yuan-Yuan Yang; Qing-Jie Xue; Xiu-Zhen Li (Current Microbiology, 2021)

Suppression of miR-4463 promotes phenotypic switching in VSMCs treated with Ox-LDL - Xueqin Wang; Hui Li; Yuetian Zhang; Qi Liu; Xiaolei Sun; Xuemei He; Qian Yang; Ping Yuan; Xiangyu Zhou (Cell and Tissue Research, 2021)

Pseudomonas laoshanensis sp. nov., isolated from peanut field soil - Ming-Qing Wang; Chu-Shu Zhang; Li-Na Yu; Wei-Qiang Yang; Kun Jiao; Kui-Jie Gong; Xiao-Yuan Chi; Jie Bi; Yu Song; Qing-Li Yang; Jian-Cheng Zhang; Gui-Wen Yang; et al. (Archives of Microbiology, 2021)

The development and application of China national landslide database and information system - Bin Tong; Yuan Li; Xudong Yang; Chunrong Yin; Xueyan Qu; Hao Fang; Bing Han; Yanling Zhang (Arabian Journal of Geosciences, 2021)

Allometric growth and carbon storage in the mangrove Sonneratia apetala - Dehuang Zhu; Dafeng Hui; Mengqi Wang; Qiong Yang; Zhen Li; Zijian Huang; Hanmeng Yuan; Shixiao Yu (Wetlands Ecology and Management, 2021)

Fracture Initiation, Gas Ejection, and Strain Waves Measured on Specimen Surfaces in Model Rock Blasting - Zong-Xian Zhang; Li Yuan Chi; Yang Qiao; De-Feng Hou (Rock Mechanics and Rock Engineering, 2021)
Crack velocity, gas ejection, and stress waves play an important role in determining delay time, designing a blast and understanding the mechanism of rock fragmentation by blasting. In this paper, the emerging times of the earliest cracks and gas ejection on the lateral surfaces of cylindrical granite specimens with a diameter of 240 mm and a length of 300 mm were determined by high-speed photography, and the strain waves measured by an instrument of dynamic strain measurement during model blasting. The results showed that: (1) the measured velocity of gas penetration into the radial cracks was in a range of 196–279 m/s; (2) the measured velocity of a radial crack extending from the blasthole to the specimen surface varied from 489 to 652 m/s; (3) the length of strain waves measured was about 2800 µs, which is approximately 1000 times greater than the detonation time. At about 2850 µs after detonation was initiated, gases were still ejected from the surface cracks, and the specimens still stood at their initial places, although surface cracks had opened widely.

Antifungal Effects of Fusion Puroindoline B on the Surface and Intracellular Environment of Aspergillus flavus - Ping-Ping Tian; Yang-Yong Lv; Ang Lv; Wen-Jing Yuan; Shuai-Bing Zhang; Na Li; Yuan-Sen Hu (Probiotics and Antimicrobial Proteins, 2021)

Seed-specific expression of TaYUC10 significantly increases auxin and protein content in wheat seeds - Yanlin Yang; Na Li; Wenrong Hui; Binjie Yuan; Pan Fan; Jingxia Liu; Honggang Wang; Deshun Feng (Plant Cell Reports, 2021)

Gender Role, But Not Sex, Shapes Humans’ Susceptibility to Emotion - Jiajin Yuan; Hong Li; Quanshan Long; Jiemin Yang; Tatia M. C. Lee; Dandan Zhang (Neuroscience Bulletin, 2021)

Arbuscular mycorrhizal fungus–induced decrease in phosphorus loss due to leaching in red soils under simulated heavy rainfall - Yongmei He; Rui Yang; Gang Lei; Mingrui Li; Tianguo Li; Fangdong Zhan; Yuan Li (Journal of Soils and Sediments, 2021)

Comparative analysis of H3K4 and H3K27 trimethylations in two contrasting Tibetan hulless barely varieties on powdery mildew infection - Sang Zha; Chunbao Yang; Xingquan Zeng; Zeqing Li; Yulin Wang; Hongjun Yuan; Mingzhai Yu; Qijun Xu (Journal of Plant Pathology, 2021)

Reproductive Parameters of Captive Female Northern White-Cheeked (Nomascus leucogenys) and Yellow-Cheeked (Nomascus gabriellae) Gibbons - Penglai Fan; Xin He; Yuzhao Yang; Xuefeng Liu; Haibo Zhang; Li Yuan; Wu Chen; Dingzhen Liu; Pengfei Fan (International Journal of Primatology, 2021)

Gentianella acuta prevents acute myocardial infarction induced by isoproterenol in rats via inhibition of galectin-3/TLR4/MyD88/NF-кB inflammatory signalling - Jia-Huan Sun; Hong-Xia Yang; Ting-Ting Yao; Yuan Li; Lin Ruan; Geng-Rui Xu; Chuang Zhang; Guo-Xin Guo; Ai-Ying Li (Inflammopharmacology, 2021)

Facile in situ synthesis of silver nanocomposites based on cellulosic paper for photocatalytic applications - Zhengqiu Yuan; Huizhi Yang; Pan Xu; Chengfeng Li; Jian Jian; Jianxian Zeng; Lingwei Zeng; Yuguang Sui; Hu Zhou (Environmental Science and Pollution Research, 2021)

Nonlinear decoupling of autotrophic and heterotrophic soil respiration in response to drought duration and N addition in a meadow steppe - Bo Meng; Raúl Ochoa-Hueso; Junqin Li; Shangzhi Zhong; Yuan Yao; Xuechen Yang; Scott L. Collins; Wei Sun (Biology and Fertility of Soils, 2021)

An Intra-Oceanic Subduction System Influenced by Ridge Subduction in the Diyanmiao Subduction Accretionary Complex of the Xar Moron Area, Eastern Margin of the Central Asian Orogenic Belt - Yang Cheng; Qinghui Xiao; Tingdong Li; Liquan Xu; Yuxu Fan; Yan Li; Lingjun Guo; Jinli Pang; Weiming Yuan (Journal of Earth Science, 2021)

Hourly extreme precipitation changes under the influences of regional and urbanization effects in Beijing - Yufeng Yuan; Panmao Zhai; Yang Chen; Jian Li (International Journal of Climatology, 2021)
Short duration extreme precipitation has devastating impacts on city area. Local urbanization effects, superimposed upon regional climate change, complicate examination of long‐term changes in short duration precipitation extremes in urban areas. Based on high‐quality rain gauge observations of summer time hourly precipitation in Beijing Region over 1977–2013, this study reveals that despite the general drying tendency for North China, the urban area of Beijing has experienced more hourly precipitation extremes (HPE) than the suburban area since 2004, coinciding with the surge in the growth of urban built‐up areas. These hourly urban precipitation extremes are increasingly inclined to occurring during night‐time, especially during 1800 LST to 0200 LST (UCT+8). On the one hand, the amplified urban heat inland effect, which was more significant at night‐time, seems to have facilitated formation of more intense small scale thermal‐low and resultant ascending branch; on the other hand, it has favoured to establishing unstable stratification in the lower level. This possible mechanism explains the preference of HPE in urban areas during night‐time and climate change diversity under the influence of megacity superposition.

Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex - Zhijun Zhang; Hongxing Zhang; Chun-Ming Xie; Meng Zhang; Yachen Shi; Ruize Song; Xiang Lu; Haisan Zhang; Kun Li; Bi Wang; Yongfeng Yang; Xianrui Li; et al. (Science China Life Sciences, 2021)

Research on the effects of diesel engine exhaust transport distance on particulate microstructure - Yang Zhao; Mingdi Li; Guangju Xu; Shuai Liu; Yinnan Yuan; Zhong Wang (Environmental Science and Pollution Research, 2021)

Experimental study and constitutive modeling of volume change behavior in unsaturated soils - Wugang Li; Qing Yang; Zhijia Xue; Wenhua Liu; Yuan Hua (Bulletin of Engineering Geology and the Environment, 2021)

Fasting Increases Iron Export by Modulating Ferroportin 1 Expression Through the Ghrelin/GHSR1α/MAPK Pathway in the Liver - Qianqian Luo; Jianan Hu; Guang Yang; Xiaoyu Yuan; Zhongping Chen; Dan Wang; Yapeng Lu; Li Zhu; Guohua Wang (Biological Trace Element Research, 2021)

Late Pennsylvanian carbonate platform facies and coral reef: new insights from southern China (Guizhou Province) - Marine Maillet; Wen-Tao Huang; Xiao Li; Zhen-Yuan Yang; Chang-Qing Guan; Yong-Li Zhang; En-Pu Gong; Katsumi Ueno; Elias Samankassou (Facies, 2021)
The Pennsylvanian is characterized by intense paleoenvironmental changes related to glacio-eustatic sea-level fluctuations and major tectonic events, which affected the evolution of biocommunities. Most known Pennsylvanian tropical reefs and mounds are predominantly composed of calcareous algae (e.g. phylloid algae, Archaeolithophyllum ), calcareous sponges, fenestrate bryozoans, Tubiphytes , and microbialites. However, in Houchang (southern China), the Late Pennsylvanian carbonate platform records a large coral reef lacking any analogs in age (Gzhelian), size (80–100 m thick) and composition (high biodiversity). The large coral reef developed at the border of the Luodian intraplatform basin. The intraplatform basin is characterized by the deposition of green algal grainstone, coated grain grainstone and bioclastic packstone, grainstone, floatstone and rudstone in shallow-waters. In the deep-water shelf, lithofacies are composed of burrowed bioclastic wackestone, microbioclastic peloidal packstone, grainstone, and fine-grained burrowed wackestone and packstone. In this context, the coral reef developed on a deep-shelf margin, in a moderate to low energy depositional environment, below the FWWB. The scarcity of Pennsylvanian coral reefs suggests global unfavorable conditions, which can be attributed to a complex pattern of several environmental factors, including seawater chemistry (aragonite seas), paleoclimatic cooling related to continental glaciation, and the biological competition with the more opportunistic and adaptive phylloid algal community that occupied similar platform margin paleoenvironments. The existence of the large Bianping coral reef in southern China, as well as a few additional examples of Pennsylvanian coralliferous bioconstructions, provides evidence that coral communities were able to endure the Late Paleozoic fluctuating paleoenvironmental conditions in specific settings. One of such settings appears to have been the deep shelf margin, where low light levels decreased competition with the phylloid algal community.

Delayed impact of natural climate solutions - Zhangcai Qin; Bronson Griscom; Yao Huang; Wenping Yuan; Xiuzhi Chen; Wenjie Dong; Tingting Li; Jonathan Sanderman; Pete Smith; Fan Wang; Song Yang (Global Change Biology, 2021)

In-flight transmission cluster of COVID-19: a retrospective case series - Naibin Yang; Yuefei Shen; Chunwei Shi; Ada Hoi Yan Ma; Xie Zhang; Xiaomin Jian; Liping Wang; Jiejun Shi; Chunyang Wu; Guoxiang Li; Yuan Fu; Keyin Wang; et al. (Infectious Diseases, 2020)

Magnesium decreases aluminum accumulation and plays a role in protecting maize from aluminum-induced oxidative stress - Xiangying Kong; Zhongping Peng; Dongxu Li; Wenna Ma; Ruidong An; Dawood Khan; Xinxun Wang; Yuan Liu; En Yang; Yuzhi He; Liqngquan Wu; Baige Zhang; et al. (Plant and Soil, 2020)

Intramuscular injection of tetracycline decreased gut microbial diversity in mouse - Jia Liu; Xi-chuan Deng; Xiao-yu Li; Zhi-bang Yang; Guang-yuan Zhang; Ting-ting Chen (Mammalian Genome, 2020)

Abscisic Acid and Gibberellins Act Antagonistically to Mediate Epigallocatechin-3-Gallate-Retarded Seed Germination and Early Seedling Growth in Tomato - Golam Jalal Ahammed; Yang Li; Yuan Cheng; Airong Liu; Shuangchen Chen; Xin Li (Journal of Plant Growth Regulation, 2020)

Geological Heritage Vulnerability Evaluation Index System for the Bamei Stone Forest on the Tibetan Plateau - Yuan Yin; Zhongquan Li; Xiaoqin Li; Dong Peng; Qizhong Wang; Shuang Yang; Fang Lai (Geoheritage, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Blood biochemistry profile of Qihe crucian carp Carassius auratus in different aquaponic systems - Yang Gao; Guorong Zhu; Yuan Tian; Kang Li; Yanjing Zhao; Junping Liang; Qianhong Gu; Xuejun Li (Environmental Science and Pollution Research, 2020)

Deformation and failure of a high-steep slope induced by multi-layer coal mining - Jian-le Yu; Jian-jun Zhao; Hao-yuan Yan; Qi-yi Lai; Run-qiu Huang; Xiu-wei Liu; Yang-chnn Li (Journal of Mountain Science, 2020)

Chemical constituents from common vetch ( Vicia sativa L.) and their antioxidant and cytotoxic activities - Li-Fang Liu; Wen-Hai Li; Man-Yu Li; Xiao-Zhen Wu; Fan Yang; Jia-Nan Xu; Cheng-Shan Yuan (Natural Product Research, 2020)

Functional expression and characterization of an endo-1,4-β-mannosidase from Triticum aestivum in Pichia pastoris - Shuai-Bing Zhang; Wei-Ji Zhang; Na Li; Huan-Chen Zhai; Yang-Yong Lv; Yuan-Sen Hu; Jing-Ping Cai (Biologia, 2020)

Surface display system for probiotics and its application in aquaculture - Yuan‐Yuan Yao; Ya‐Lin Yang; Chen‐Chen Gao; Feng‐Li Zhang; Rui Xia; Dong Li; Juan Hu; Chao Ran; Zhen Zhang; Jihong Liu‐Clarke; Zhi‐Gang Zhou (Reviews in Aquaculture, 2020)
Aquaculture is a fast‐growing and rapidly expanding industry in the world. Probiotics are widely used in aquaculture and have provided benefits to aquatic animal health, and it is also a promising alternative to antibiotics for control of fish diseases. With the development of biotechnology, new expression systems and novel techniques for the surface display of heterologous proteins in surface of probiotics cells have been developed. This review provides an overview of the systems and strategies for displaying functional proteins on the surface of probiotics commonly used in aquaculture, which are Bacillus subtilis , Bacillus thuringiensis , lactic acid bacteria represented by Lactococcus lactis and yeast. Their applications in aquaculture especially for oral vaccine development afforded by this technology and prospects and challenges associated with this technology are also highlighted.

Sulfur isotopic compositions of sulfides along the Southwest Indian Ridge: implications for mineralization in ultramafic rocks - Teng Ding; Chunhui Tao; Ágata Alveirinho Dias; Jin Liang; Jie Chen; Bin Wu; Dongsheng Ma; Rongqing Zhang; Jia Wang; Shili Liao; Yuan Wang; Weifang Yang; et al. (Mineralium Deposita, 2020)

Isopimarane-type diterpenoids from Croton laevigatus - Man-Yu Li; Zheng-Zhi Han; Li-Fang Liu; Xiao-Zhen Wu; Wen-Jun Huang; Kai Wang; Fan Yang; Cheng-Shan Yuan (Natural Product Research, 2020)

Creation of fertility-restored materials for Ogura CMS in Brassica oleracea by introducing Rfo gene from Brassica napus via an allotriploid strategy - Hai-long Yu; Zhi-yuan Li; Wen-jing Ren; Feng-qing Han; Li-mei Yang; Mu Zhuang; Hong-hao Lv; Yu-mei Liu; Zhi-yuan Fang; Yang-yong Zhang (Theoretical and Applied Genetics, 2020)
Key message Ogura CMS fertility-restored materials, with 18 chromosomes, normal seed setting, stable fertility and closer genetic background to the parent Chinese kale, were successfully developed in B. oleracea via a triploid strategy for the first time. Abstract Ogura cytoplasmic male sterility (CMS) is the most widely used sterile type in seed production for commercial hybrids of Brassica oleracea vegetables. However, the natural Ogura CMS restorer line has not been found in B. oleracea crops. In this study, the triploid strategy was used with the aim to create euploid B. oleracea progenies with the Rfo gene. The allotriploid AAC hybrid YL2 was used as a male parent to backcross with Ogura CMS Chinese kale. After successive backcrosses, the BC 2 Rfo -positive individual 16CMSF2-11 and its BC 3 progenies, with 18 chromosomes, were developed, which were morphologically identical to the parent Chinese kale. Compared with F 1 and BC 1 plants, it showed stable fertility performance, and regular meiosis behavior and could produce seeds normally under natural pollination. The genomic composition analysis of Rfo -positive progenies by using molecular markers showed that more than 87% of the C-genome components of BC 3 Rfo -progenies recovered to the parent Chinese kale, while most or all of the A n -genome segments were lost in 16CMSF2-11 and its progenies. The results suggested that the genetic background of Rfo -positive individuals was closer to that of the parent Chinese kale along with backcrossing. Hereof, the Ogura CMS fertility-restored materials of Chinese kale were successfully created via triploid strategy for the first time, providing a bridge for utilizing the Ogura CMS B. oleracea germplasm in the future. Moreover, our study indicates that the triploid strategy is effective for transferring genes from B. napus into B. oleracea .

Chloroplast DNA phylogeography of the Holly mangrove Acanthus ilicifolius in the Indo-West Pacific - Wuxia Guo; Achyut Kumar Banerjee; Wei Lun Ng; Yang Yuan; Weixi Li; Yelin Huang (Hydrobiologia, 2020)

Effects of biochar properties on the bioremediation of the petroleum-contaminated soil from a shale-gas field - Hong-Yang Ren; Zi-Jing Wei; Yan Wang; Yuan-Peng Deng; Ming-Yu Li; Bing Wang (Environmental Science and Pollution Research, 2020)

Transcriptome analysis of rice leaves in response to Rhizoctonia solani infection and reveals a novel regulatory mechanism - De Peng Yuan; Xiao Feng Xu; Woo-Jong Hong; Si Ting Wang; Xin Tong Jia; Yang Liu; Shuang Li; Zhi Min Li; Qian Sun; Qiong Mei; Shuai Li; Ki-Hong Jung; et al. (Plant Biotechnology Reports, 2020)

Evaluating Spatial Heterogeneity of Land Surface Hydrothermal Conditions in the Heihe River Basin - Yuan Zhang; Shaomin Liu; Xiao Hu; Jianghao Wang; Xiang Li; Ziwei Xu; Yanfei Ma; Rui Liu; Tongren Xu; Xiaofan Yang (Chinese Geographical Science, 2020)

Small RNA profiling reveal regulation of microRNAs in field peanut pod rot pathogen infection - Mian Wang; Chao-xin Zhang; Li-juan Pan; Tong Wang; Na Chen; Ming-na Chen; Zhen Yang; Xin-gang Guo; Shan-lin Yu; Xiao-yuan Chi (Biologia, 2020)

Nutrient factor-dependent performance of bacterial quorum sensing system during population evolution - Kelei Zhao; Jing Li; Yang Yuan; Jiafu Lin; Xinrong Wang; Yidong Guo; Yiwen Chu (Archives of Microbiology, 2020)

Research on the characterization, reactivity, and transportability of porous silicon-coated nanoscale zero-valent iron - Ruiyang Xu; Juan Li; Jun Tang; Yang Wang; Yuan Niu; Haojie Lu (Environmental Science and Pollution Research, 2020)

Molecular characterization of gut microbial shift in SD rats after death for 30 days - Huan Li; E. Yang; Siruo Zhang; Jing Zhang; Lu Yuan; Ruina Liu; Shakir Ullah; Qi Wang; Nosheen Mushtaq; Yi Shi; Cuihong An; Zhenyuan Wang; et al. (Archives of Microbiology, 2020)

A minor QTL, SG3, encoding an R2R3-MYB protein, negatively controls grain length in rice - Qiuping Li; Li Lu; Haiyang Liu; Xufeng Bai; Xin Zhou; Bi Wu; Mengqi Yuan; Lin Yang; Yongzhong Xing (Theoretical and Applied Genetics, 2020)

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study - Shao-rui Hao; Ren Yan; Shan-yan Zhang; Jiang-shan Lian; Huan Cai; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

SCFAs induce autophagy in intestinal epithelial cells and relieve colitis by stabilizing HIF-1α - Chao Zhou; Liangzi Li; Teming Li; Lihua Sun; Jiuheng Yin; Haidi Guan; Liucan Wang; Hongbing Zhu; Peng Xu; Xin Fan; Baifa Sheng; Weidong Xiao; et al. (Journal of Molecular Medicine, 2020)

Privet golden leaves adapt unexpectedly well to light changes - Ming Yuan; Bo Huang; Li-Hua Dong; Qiao-Hong Han; Yong Yang; Chun-Bang Ding; Chao Hu; Yang-Er Chen; Zhong-Wei Zhang; Shu Yuan (Horticulture, Environment, and Biotechnology, 2020)

A family cluster of severe acute respiratory syndrome coronavirus 2 infections - Xuesong Gao; Zheng Yuan; Di Yang; Hongjie Li; Yijin Zhang; Ping Gao; Xiaomin Liu; Wenshan Zhao; Te Xiao; Xuefei Duan (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Single-cell transcriptome analysis of the novel coronavirus (SARS-CoV-2) associated gene ACE2 expression in normal and non-obstructive azoospermia (NOA) human male testes - Xixi Liu; Yidong Chen; Wenhao Tang; Li Zhang; Wei Chen; Zhiqiang Yan; Peng Yuan; Ming Yang; Siming Kong; Liying Yan; Jie Qiao (Science China Life Sciences, 2020)

Whole brain radiotherapy induces cognitive dysfunction in mice: key role of gut microbiota - Xiao-Xiao Luo; Chun Yang; Gao-Feng Zhan; Shan Li; Dong-Yu Hua; Ai-Lin Luo; Xiang-Lin Yuan (Psychopharmacology, 2020)

The trichome-specific acetolactate synthase NtALS1 gene, is involved in acylsugar biosynthesis in tobacco (Nicotiana tabacum L.) - Ai-Xia Chang; Biao Chen; Ai-Guo Yang; Ri-Sheng Hu; Quan-Fu Feng; Ming Chen; Xiao-Ning Yang; Cheng-Gang Luo; Yang-Yang Li; Yuan-Ying Wang (Planta, 2020)

Astrocytic GABAB Receptors in Mouse Hippocampus Control Responses to Behavioral Challenges through Astrocytic BDNF - Ji-Hong Liu; Ze-Lin Li; Yi-Si Liu; Huai-De Chu; Neng-Yuan Hu; Ding-Yu Wu; Lang Huang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2020)

Centrifuge modeling of the pile foundation reinforcement on slopes subjected to uneven settlement - Liqiu Ma; Kun Yang; Wenzhong Yuan; Lingao Li; Yanxun Wei; Changhui Ma; Fangyue Luo; Ga Zhang (Bulletin of Engineering Geology and the Environment, 2020)

Comparative transcriptomic analysis of fireflies (Coleoptera: Lampyridae) to explore the molecular adaptations to fresh water - Qi‐Lin Zhang; Hong‐Wei Li; Zhi‐Xiang Dong; Xiao‐Jie Yang; Lian‐Bing Lin; Jun‐Yuan Chen; Ming‐Long Yuan (Molecular Ecology, 2020)
Aquatic insects are well adapted to freshwater environments, but the molecular basis of these adaptations remains largely unknown. Most firefly species (Coleoptera: Lampyridae) are terrestrial, but the larvae of several species are aquatic. Here, larval and adult transcriptomes from Aquatica leii (freshwater) and Lychnuris praetexta (terrestrial) were generated to test whether the genes associated with metabolic efficiency and morphology have undergone adaptive evolution to fresh water. The aquatic fireflies had a significantly lower ratio of nonsynonymous to synonymous substitutions than the terrestrial insects, indicating a genomewide evolutionary constraint in the aquatic fireflies. We identified 341 fast‐evolving genes and 116 positively selected genes in the aquatic fireflies. Of these, 76 genes exhibiting both fast evolution and positive selection were primarily involved in ATP production, energy metabolism and the hypoxia response. We identified 7,271 differentially expressed genes (DEGs) in A . leii (adults versus larvae) and 8,309 DEGs in L . praetexta (adults versus larvae). DEGs specific to the aquatic firefly ( n = 1,445) were screened via interspecific comparisons ( A . leii versus L . praetexta ) and were significantly enriched for genes involved in metabolic efficiency (e.g., ATP production, hypoxia, and immune responses) and certain aspects of morphology (e.g., cuticle chitin, tracheal and compound eye morphology). These results indicate that sequence and expression‐level changes in genes associated with both metabolic efficiency and morphological attributes related to the freshwater lifestyle contributed to freshwater adaptation in fireflies. This study provides new insights into the molecular mechanisms of aquatic adaptation in insects.

Moderate parasitoidism on pollinators contributes to population oscillations and increases species diversity in the fig-fig wasp community - Lin Wang; Li-Yuan Yang; Feng Zhang; Rui-Wu Wang (Theoretical Ecology, 2020)