Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases - Sisi Zhang; Caterina Riccardi; Douglas Kamen; James Reilly; John Mattila; Hanne Bak; Hui Xiao; Ning Li (Pharmaceutical Research, 2022)

β-Catenin Deletion in Regional Neural Progenitors Leads to Congenital Hydrocephalus in Mice - Lin Ma; Yanhua Du; Xiangjie Xu; Hexi Feng; Yi Hui; Nan Li; Guanyu Jiang; Xiaoqing Zhang; Xiaocui Li; Ling Liu (Neuroscience Bulletin, 2022)

A dynamically evolving war between autophagy and pathogenic microorganisms - Qianqian Zheng; Liangwei Duan; Yang Zhang; Jiaoyang Li; Shiyu Zhang; Hui Wang (Journal of Zhejiang University-SCIENCE B, 2022)

Retraction Note to: Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes - Michael Nothnagel; Guangyao Fan; Fei Guo; Yongfeng He; Yiping Hou; Shengping Hu; Jiang Huang; Xianhua Jiang; Wook Kim; Kicheol Kim; Chengtao Li; Hui Li; et al. (Human Genetics, 2022)

N-acetylcysteine alleviates pulmonary inflammatory response during benzo[a]pyrene-evoked acute lung injury - Hui Zhao; Lin Fu; Hui-Xian Xiang; Ying Xiang; Meng-Die Li; Bian-Bian Lv; Zhu-Xia Tan; Lan Gao; Cheng Zhang; De-Xiang Xu (Environmental Science and Pollution Research, 2022)

Experimental Research on Cumulative Damage Law of Microcrystalline Limestone under Fixed Equivalent Cyclic Blasting Load - Anrun Li; Hui Deng; Haojie Zhang (Arabian Journal of Geosciences, 2022)

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

A Novel Hybrid Decompose-Ensemble Strategy with a VMD-BPNN Approach for Daily Streamflow Estimating - Hui Hu; Jianfeng Zhang; Tao Li (Water Resources Management, 2021)

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Variations in soil properties rather than functional gene abundances dominate soil phosphorus dynamics under short-term nitrogen input - Bing Han; Jingjing Li; Kesi Liu; Hui Zhang; Xiaoting Wei; Xinqing Shao (Plant and Soil, 2021)

Correction to: μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

Clinical and Molecular Features of POLG-Related Sensory Ataxic Neuropathy with Dysarthria and Ophthalmoparesis - Li-Xi Li; Li-Ting Jiang; You-Gui Pan; Xiao-Long Zhang; Li-Zhen Pan; Zhi-Yu Nie; Yu-Hui Chen; Ling-Jing Jin (Journal of Molecular Neuroscience, 2021)

Major histocompatibility complex class II genetic diversity and the genetic influence on gut microbiota in Guizhou minipigs - Gang Yao; Min Fan; Jian Zhang; Yanjun Wu; Hai Zhao; Hui Zhang; Longfei Li; Shuguang Wu (Folia Microbiologica, 2021)

Driving forces for recovery of forest vegetation after harvesting a subalpine oak forest in eastern Tibetan Plateau - Qinli Xiong; Lingjuan Li; Xiaojin Luo; Xingjin He; Lin Zhang; Kaiwen Pan; Chenggang Liu; Hui Sun (Environmental Science and Pollution Research, 2021)

Australian propolis ethanol extract exerts antibacterial activity against methicillin-resistant Staphylococcus aureus by mechanisms of disrupting cell structure, reversing resistance, and resisting biofilm - Fei Wang; Hui Liu; Junya Li; Wenwen Zhang; Bin Jiang; Hongzhuan Xuan (Brazilian Journal of Microbiology, 2021)

Evaluation of four artificial diets on demography parameters of Neoseiulus barkeri - Ya-Ying Li; Jin-Ge Yuan; Ming-Xiu Liu; Zi-Hui Zhang; Hai-Wei Zhou; Huai Liu (BioControl, 2021)

The first third-generation HIV-1 circulating recombinant form (CRF114_0155) identified in central China - Yang Li; Yan Zhang; Hongye Wang; Long Liu; Hui Chen; Shuanhu Zhang; Wenying Wu; Rongge Yang (Archives of Virology, 2021)

Differential effects of altered precipitation regimes on soil carbon cycles in arid versus humid terrestrial ecosystems - Bin Wang; Yali Chen; Yan Li; Hui Zhang; Kai Yue; Xingchang Wang; Yuandan Ma; Jian Chen; Meng Sun; Zhuo Chen; Qiqian Wu (Global Change Biology, 2021)
Changes in precipitation regimes have significant effects on soil carbon (C) cycles; however, these effects may vary in arid versus humid areas. Additionally, the corresponding details of soil C cycles in response to altered precipitation regimes have not been well documented. Here, a meta‐analysis was performed using 845 pairwise observations (control vs. increased or decreased precipitation) from 214 published articles to quantify the responses of the input process of exogenous C, the contents of various forms of C in soil, and the soil‐atmosphere C fluxes relative to increased or decreased precipitation. The results showed that the effects of altered precipitation regimes did not differ between rainfall and snowfall. Increased precipitation significantly enhanced the soil C inputs, pools and outputs by 18.17%, 18.50%, and 21.04%, respectively, while decreased precipitation led to a significant decline in these soil C parameters by 10.18%, 9.96%, and 17.98%, respectively. The effects of increased precipitation on soil C cycles were more significant in arid areas (where mean annual precipitation, MAP

Progress in the pretreatment and analysis of N-nitrosamines: an update since 2010 - Yu Bian; Yuan Zhang; Yu Zhou; Guo-hui Li; Xue-song Feng (Critical Reviews in Food Science and Nutrition, 2021)

Late Silurian to early Devonian development of the Chingiz accretion arc, West Junggar: insights into accretion arc evolution in the Central Asia Orogenic Belt - Yichao Chen; Ji’En Zhang; Wenjiao Xiao; Renjie Zhou; Shuaihua Song; Zhiyong Zhang; Songjian Ao; Miao Sang; Qian W.L. Zhang; Rui Li; Zhen M.G. Li; Yin Liu; et al. (International Geology Review, 2021)

Alkaloids with acetylcholinesterase inhibitory activity from Corydalis racemosa (Thunb.) Pers - Hui-Na Yao; Zhi-Tian Peng; Yun-Feng Zhang; Di-Fa Liu; Bing-Feng Huang; Peng-Fei Tu; Yun-Fang Zhao; Hui-Xia Huo; Jun Li (Natural Product Research, 2021)

Abnormal meiosis in fertile and sterile triploid cyprinid fish - Chun Zhang; Qi Li; La Zhu; Wangchao He; Conghui Yang; Hui Zhang; Yu Sun; Luojing Zhou; Yuandong Sun; Shurun Zhu; Chang Wu; Min Tao; et al. (Science China Life Sciences, 2021)

Removal of roosters alters the domestic phenotype and microbial and genetic profile of hens - Hai Xiang; Siyu Chen; Hui Zhang; Xu Zhu; Dan Wang; Huagui Liu; Jikun Wang; Tao Yin; Langqing Liu; Minghua Kong; Jian Zhang; Hua Li; et al. (Science China Life Sciences, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Simulation of indoor cigarette smoke particles in a ventilated room - Yunfei Song; Quan Yang; Hui Li; Shengnan Shen; Hongbin Chen; Yicang Huang; Guoqing Zhang; Jiayue Wang; Wei Wei (Air Quality, Atmosphere & Health, 2021)

Recent improvements to the physical model of the Bohai Sea, the Yellow Sea and the East China Sea Operational Oceanography Forecasting System - Ang Li; Xueming Zhu; Yunfei Zhang; Shihe Ren; Miaoyin Zhang; Ziqing Zu; Hui Wang (Acta Oceanologica Sinica, 2021)

Divergence in the Aquilegia ecalcarata complex is correlated with geography and climate oscillations: Evidence from plastid genome data - Cheng Xue; Fang‐Dong Geng; Jiao‐Jie Li; Dan‐Qing Zhang; Fei Gao; Lei Huang; Xiao‐Hui Zhang; Ju‐Qing Kang; Jian‐Qiang Zhang; Yi Ren (Molecular Ecology, 2021)
Quaternary climate oscillations and geographical heterogeneity play important roles in determining species and genetic diversity distribution patterns, but how these factors affect the migration and differentiation of East Asian plants species at the population level remains poorly understood. The Aquilegia ecalcarata complex, a group that originated in the Late Tertiary and is widely distributed throughout East Asia, displays high genetic variation that is suitable for studying elaborate phylogeographic patterns and demographic history related to the impact of Quaternary climate and geography. We used plastid genome data from 322 individuals in 60 populations of the A . ecalcarata complex to thoroughly explore the impact of Quaternary climate oscillations and geography on the phylogeographic patterns and demographic history of the A . ecalcarata complex through a series of phylogenetic, divergence time estimation, and demographic history analyses. The dry, cold climate and frequent climate oscillations that occurred during the early Pleistocene and the Mid‐Pleistocene transition led to the differentiation of the A . ecalcarata complex, which was isolated in various areas. Geographically, the A . ecalcarata complex can be divided into Eastern and Western Clades and five subclades, which conform to the divergence of the East Asian flora. Our results clearly show the impact of Quaternary climate and geography on evolutionary history at the population level. These findings promote the understanding of the relationship between plant genetic differentiation and climate and geographical factors of East Asia at the population level.

Dynamic evolution of eukaryotic mitochondrial and nuclear genomes: a case study in the gourmet pine mushroom Tricholoma matsutake - Shu Zhang; Xue Bai; Li‐Yuan Ren; Hui‐Hui Sun; Hui‐Ping Tang; Lu‐Min Vaario; Jianping Xu; Yong‐Jie Zhang (Environmental Microbiology, 2021)
Summary Fungi, as eukaryotic organisms, contain two genomes, the mitochondrial genome and the nuclear genome, in their cells. How the two genomes evolve and correlate to each other is debated. Herein, taking the gourmet pine mushroom Tricholoma matsutake as an example, we performed comparative mitogenomic analysis using samples collected from diverse locations and compared the evolution of the two genomes. The T. matsutake mitogenome encodes 49 genes and is rich of repetitive and non‐coding DNAs. Six genes were invaded by up to 11 group I introns, with one cox1 intron cox1P372 showing presence/absence dynamics among different samples. Bioinformatic analyses suggested limited or no evidence of mitochondrial heteroplasmy. Interestingly, hundreds of mitochondrial DNA fragments were found in the nuclear genome, with several larger than 500 nt confirmed by PCR assays and read count comparisons, indicating clear evidence of transfer of mitochondrial DNA into the nuclear genome. Nuclear DNA of T. matsutake showed a higher mutation rate than mitochondrial DNA. Furthermore, we found evidence of incongruence between phylogenetic trees derived from mitogenome and nuclear DNA sequences. Together, our results reveal the dynamic genome evolution of the gourmet pine mushroom.

Foundation and Prospects of Wild Population Reconstruction of Acipenser dabryanus - Junyi Li; Hao Du; Jinming Wu; Hui Zhang; Li Shen; Qiwei Wei (Fishes, 2021)
Acipenser dabryanus is an endemic fish inhabiting the upper reaches of the Yangtze River in China. It is classified as a first-class nationally protected animal in China and is listed in the International Union for Conservation of Nature (IUCN) Red List of Critically Endangered Species (CR). Recently, there has been a decrease in natural reproduction of A. dabryanus, and the wild population is almost extinct. This paper summarizes the changes observed in the natural population of A.dabryanus and the factors leading to its endangerment. Based on the process of artificial propagation and achievement of relevant protection goals, this paper presents the concept and technical framework for reconstruction of the wild population of A. dabryanus. In addition, by comprehensively reviewing the research findings and existing problems in the resource protection and monitoring of A. dabryanus in recent years, we assessed the possibility of wild population reconstruction and resource restoration for A. dabryanus. Reconstruction and restoration measures for the wild population of A. dabryanus are proposed, with the aim of providing a scientific basis for the reconstruction of the natural population and the improvement and restoration of critical habitat of this species. Furthermore, it is hoped that this paper will serve as a reference for the protection and restoration of other endangered fishes.

Pleosporalins H and I, two new heptaketides from the endophytic fungus Pleosporales sp. F46 by using OSMAC strategy - Hong-Xia Yang; Xiao-Ping Peng; Han Gao; Hui-Min Zhang; Zi-Ru Wang; Gang Li; Hong-Xiang Lou (Natural Product Research, 2021)

Whole-genome resequencing of 240 Gossypium barbadense accessions reveals genetic variation and genes associated with fiber strength and lint percentage - Jingwen Yu; Yixuan Hui; Jinhong Chen; Hurong Yu; Xinpeng Gao; Zhaohui Zhang; Qin Li; Shuijin Zhu; Tianlun Zhao (Theoretical and Applied Genetics, 2021)

Genetic and molecular characterization of determinant of six-rowed spike of barley carrying vrs1.a4 - Jin-Hui Wang; Zhen-Mei Xu; Xue-Bing Qiu; Li-Lan Li; Shui-Yang Yu; Tao Li; Yan-Yan Tang; Xi Pu; Juan-Yu Zhang; Hai-Li Zhang; Jun-Jun Liang; Ya-Wei Tang; et al. (Theoretical and Applied Genetics, 2021)

Functional analysis of indole 3-hexanoic acid as a novel auxin from Arabidopsis thaliana - Ping Song; Hui Xu; Jixiu Zhang; Huatao Chen; Li Li; Yana Qu; Feng Lin; Qun Zhang (Planta, 2021)

A review of the botany, traditional uses, phytochemistry and pharmacology of Nepeta tenuifolia Briq. - Mingqiu Shan; Yulan Jiang; Yuanyuan Fu; Yongyi Zhou; Zhihui Lu; Sheng Yu; Hui Yan; Chanchan Liu; Peidong Chen; Beihua Bao; Li Zhang; Qinan Wu (Phytochemistry Reviews, 2021)

Influence of sedimentation rate on the environmental capacity of total nitrogen in the water of Bohai Bay, China - Yan Zhang; Anding Li; Ye Tian; Bin Zhou; Man Chai; Hui Li; Qiongqiong Liu; Hui Zeng; Weijie Xu (Journal of Soils and Sediments, 2021)

Ectomycorrhizal symbioses increase soil calcium availability and water use efficiency of Quercus acutissima seedlings under drought stress - Yanan Li; Tengzi Zhang; Yongbin Zhou; Xiaoming Zou; You Yin; Hui Li; Liying Liu; Songzhu Zhang (European Journal of Forest Research, 2021)

Occurrence and distribution characteristics of antibiotic resistance genes in sediments between urban and rural of the Liaohe River Basin, China - Guangshui Na; Keyu Zhang; Hui Gao; Ruijing Li; Shuaichen Jin; Fuqiang Zhao; Haibo Zhang; Shisheng Li (Environmental Science and Pollution Research, 2021)

High-K calc-alkaline to shoshonitic intrusions in SE Tibet: implications for metasomatized lithospheric mantle beneath an active continental margin - Ren-Zhi Zhu; Ewa Słaby; Shao-Cong Lai; Li-Hui Chen; Jiangfeng Qin; Chao Zhang; Shaowei Zhao; Fangyi Zhang; Wen-hang Liu; Mike Fowler (Contributions to Mineralogy and Petrology, 2021)

Vulnerability of glacier change in the Tianshan Mountains region of China - Xingran Cai; Zhongqin Li; Hui Zhang; Chunhai Xu (Journal of Geographical Sciences, 2021)

Performance evaluation of the filters with adaptive factor and fading factor for GNSS/INS integrated systems - Chen Jiang; Shubi Zhang; Hui Li; Zhen Li (GPS Solutions, 2021)

A new indole alkaloid with HUVEC proliferation activities from Nauclea officinalis - Shi-Ying Mai; Yong-Hui Li; Xu-Guang Zhang; Yi-Ran Wang; Jun-Qing Zhang; An Jia (Natural Product Research, 2021)

Experimental study on integrated and autonomous conductivity-temperature-depth (CTD) sensor applied for underwater glider - Bin Lv; Hai-lin Liu; Yi-fan Hu; Cheng-xuan Wu; Jie Liu; Hai-jing He; Jie Chen; Jian Yuan; Zhao-wen Zhang; Lin Cao; Hui Li (Marine Georesources & Geotechnology, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

Transcriptome Sequencing of a Novel Albino Mutant of Hexaploid Sweetpotato - Mohamed Hamed Arisha; Yan Hui; Muhammad Qadir Ahmad; Tang Wei; Kou Meng; Liu Yaju; Wang Xin; Zhang Yungang; Li Qiang (Plant Molecular Biology Reporter, 2021)

Developing a two-step improved damage creep constitutive model based on soft rock saturation-loss cycle triaxial creep test - Anrun Li; Hui Deng; Haojie Zhang; Mingliang Jiang; Hanhan Liu; Yuyue Xiao; Jing Wen (Natural Hazards, 2021)

Stability mechanism recognition and failure risk assessment on a high slope by synthesizing different analysis methods - Changqing Qi; Liuyang Li; Ruoqi Li; Feifei Gan; Wentao Zhang; Hui Han (Natural Hazards, 2021)

BDNF Participates in Chronic Constriction Injury-Induced Neuropathic Pain via Transcriptionally Activating P2X7 in Primary Sensory Neurons - Yi Wu; Zhiwen Shen; Hui Xu; Kun Zhang; Mingyan Guo; Fei Wang; Junhua Li (Molecular Neurobiology, 2021)

Nutrient Uptake and Distribution in Mycorrhizal Cuttings of Populus × canadensis ‘Neva’ Under Drought Stress - Li Li; Haoqiang Zhang; Ming Tang; Hui Chen (Journal of Soil Science and Plant Nutrition, 2021)

Human Amniotic Epithelial Cells Alleviate a Mouse Model of Parkinson’s Disease Mainly by Neuroprotective, Anti-Oxidative and Anti-Inflammatory Factors - Jiaofei Zhang; Hui Li; Hao Yang; Jianhua Lin; You Wang; Qianjun Zhang; Wei-Qiang Gao; Huiming Xu (Journal of Neuroimmune Pharmacology, 2021)

Identification of a major QTL related to resistance to soybean mosaic virus in diverse soybean genetic populations - Jiahao Chu; Wenlong Li; Dongri Piao; Feng Lin; Xiaobo Huo; Hua Zhang; Hui Du; Youbin Kong; Yuan Jin; Xihuan Li; Caiying Zhang (Euphytica, 2021)

Spatio-temporal characteristics and control strategies in the early period of COVID-19 spread: a case study of the mainland China - Jiachen Ning; Yuhan Chu; Xixi Liu; Daojun Zhang; Jinting Zhang; Wangjun Li; Hui Zhang (Environmental Science and Pollution Research, 2021)

Long-term effects of phytoextraction by a poplar clone on the concentration, fractionation, and transportation of heavy metals in mine tailings - Yange Suo; Ning Tang; Hui Li; Giuseppe Corti; Lijuan Jiang; Zhongliang Huang; Zhiguo Zhang; Jing Huang; Zijian Wu; Chongling Feng; Xuan Zhang (Environmental Science and Pollution Research, 2021)

Polystyrene microplastics induce blood–testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats - Shengda Li; Qimeng Wang; Hui Yu; Long Yang; Yiqing Sun; Ning Xu; Nana Wang; Zhimin Lei; Junyu Hou; Yinchuan Jin; Hongqin Zhang; Lianqin Li; et al. (Environmental Science and Pollution Research, 2021)

Characteristics of tailpipe volatile halogenated hydrocarbon (VHC) emissions from in-use vehicles during real-world driving - Hui Mei; Menglei Wang; Boqiang Jin; Rencheng Zhu; Yunjing Wang; Lulu Wang; Shunyi Li; Ruiqin Zhang; Xiaofeng Bao (Environmental Science and Pollution Research, 2021)

Uncovering the in-use metal stocks and implied recycling potential in electric vehicle batteries considering cascaded use: a case study of China - Hui Yang; Xiaolong Song; Xihua Zhang; Bin Lu; Dong Yang; Bo Li (Environmental Science and Pollution Research, 2021)

Effects of Vegetation Restoration on Soil Enzyme Activity in Copper and Coal Mining Areas - Hui Sun; Jianfeng Zhang; Rongjia Wang; Zongtai Li; Shiyong Sun; Guanghua Qin; Yumin Song (Environmental Management, 2021)

Biodegradation of Di-n-butyl phthalate in rhizosphere and growth-promoting effect of Cucumis sativus Linn. by a novel Pseudomonas sp. DNB-S1 - Shuqin Li; Lei Wang; Ying Li; Fuxin Huang; Hui Yu; Ying Zhang; Rui Li; Zhaobo Chen; Ningrui Wei; Zhengzhe Yu (Ecotoxicology, 2021)

Methane Concentration in the Heartwood of Living Trees and Estimated Methane Emission on Stems in Upland Forests - Zhi-Ping Wang; Huan-Long Li; Hong-Hui Wu; Shi-Jie Han; Jian-Hui Huang; Xi-Mei Zhang; Xing-Guo Han (Ecosystems, 2021)

Characterization, Sources and Excessive Cancer Risk of PM2.5-Bound Polycyclic Aromatic Hydrocarbons in Different Green Spaces in Lin’an, Hangzhou, China - Fang Huang; Yinke Zhang; Yilei Lou; Xiaolu Li; Tianran Zhang; Hui Yu; Chuyang Yuan; Qun Tong; Feng Qi; Feng Shao (Bulletin of Environmental Contamination and Toxicology, 2021)

Microfossils from nodular cherts in the Middle Ordovician Yijianfang Formation carbonates (Well YJ1X), Tarim Basin, China - Zhi-li Zhang; Fan-wei Meng; Quan-feng Zheng; Hui-li Li; Leiming Yin; Xuejun Yuan; Kui Yan; Naveed Ahsane; Saif Ur Rehmane (Carbonates and Evaporites, 2021)

An experimental study on cutting tool hardness optimization for shield TBMs during dense fine silty sand ground tunneling - Xiao-Ping Zhang; Shao-Hui Tang; Quan-Sheng Liu; Xin-Bin Tu; Peng Chen; Fang-Yi Li (Bulletin of Engineering Geology and the Environment, 2021)

Metabolic pathway analysis of walnut endophytic bacterium Bacillus subtilis HB1310 related to lipid production from fermentation of cotton stalk hydrolysate based on genome sequencing - Qin Zhang; Panpan Liu; Yanbin Li; Hui Jiang (Biotechnology Letters, 2021)

3D Step-by-step inversion strategy for audio magnetotellurics data based on unstructured mesh - San Cheng; Zhi-Yong Zhang; Feng Zhou; Man Li; Hui Chen; Fu-Sheng Shi; Lin-Pin Huang; Yong Li (Applied Geophysics, 2021)

Taxonomic description of Pseudomonas rhizovicinus sp. nov., isolated from the rhizosphere of a desert shrub Haloxylon ammodendron - Ao-Lei He; Hui-Ru Li; Hui-Ping Li; Jing-Yi Gou; Jia Chen; Qi Zhao; Jin-Lin Zhang (Antonie van Leeuwenhoek, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

Gas permeability evolution of granite under confining pressure unloading tests - Dawei Hu; Jun Li; Hui Zhou; Jingjing Lu; Dongdong Ma; Fan Zhang (European Journal of Environmental and Civil Engineering, 2021)

Mesozoic intracontinental deformation of the Alxa Block in the middle part of Central Asian Orogenic Belt: A review - Jin Zhang; Yannan Wang; Junfeng Qu; Beihang Zhang; Heng Zhao; Long Yun; Tianyi Li; Pengfei Niu; Fengjun Nie; Jie Hui; Yiping Zhang (International Geology Review, 2021)

Optimization of ultrasound and microwave-assisted extraction of sweet cherry tree branches and chemical component analysis by UPLC–MS/MS - Huimin Zhang; Hongguang Yan; Cuixiang Lu; Hui Lin; Quan Li (Trees, 2021)

Hippocampal Interneurons are Required for Trace Eyeblink Conditioning in Mice - Wei-Wei Zhang; Rong-Rong Li; Jie Zhang; Jie Yan; Qian-Hui Zhang; Zhi-An Hu; Bo Hu; Zhong-Xiang Yao; Hao Chen (Neuroscience Bulletin, 2021)
While the hippocampus has been implicated in supporting the association among time-separated events, the underlying cellular mechanisms have not been fully clarified. Here, we combined in vivo multi-channel recording and optogenetics to investigate the activity of hippocampal interneurons in freely-moving mice performing a trace eyeblink conditioning (tEBC) task. We found that the hippocampal interneurons exhibited conditioned stimulus (CS)-evoked sustained activity, which predicted the performance of conditioned eyeblink responses (CRs) in the early acquisition of the tEBC. Consistent with this, greater proportions of hippocampal pyramidal cells showed CS-evoked decreased activity in the early acquisition of the tEBC. Moreover, optogenetic suppression of the sustained activity in hippocampal interneurons severely impaired acquisition of the tEBC. In contrast, suppression of the sustained activity of hippocampal interneurons had no effect on the performance of well-learned CRs. Our findings highlight the role of hippocampal interneurons in the tEBC, and point to a potential cellular mechanism subserving associative learning.

Upregulated SOCC and IP3R calcium channels and subsequent elevated cytoplasmic calcium signaling promote nonalcoholic fatty liver disease by inhibiting autophagy - Lin Zhang; Yifan Zhang; Yuanqing Jiang; Xiaobing Dou; Songtao Li; Hui Chai; Qianyu Qian; Miaojuan Wang (Molecular and Cellular Biochemistry, 2021)

Magmatic-hydrothermal evolution of an unusual Mo-rich carbonatite: a case study using LA-ICP-MS fluid inclusion microanalysis and He–Ar isotopes from the Huangshui’an deposit, Qinling, China - Li Tang; Thomas Wagner; Tobias Fusswinkel; Shou-Ting Zhang; Bo Xu; Li-Hui Jia; Xin-Kai Hu (Mineralium Deposita, 2021)

Three Paralogous R2R3-MYB Genes Contribute to Delphinidin-Related Anthocyanins Synthesis in Petunia hybrida - Zhenzhu Fu; Hui Jiang; Yacong Chao; Xiaoyu Dong; Xin Yuan; Limin Wang; Jing Zhang; Menglan Xu; Huijuan Wang; Yanmin Li; Jie Gao; Hechen Zhang (Journal of Plant Growth Regulation, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Effect of substituting nitrogen fertilizer with nitrogen-fixing cyanobacteria on yield in a double-rice cropping system in southern China - Jinli Zhang; Xuening Song; Hui Wei; Weicheng Zhou; Chengrong Peng; Dunhai Li (Journal of Applied Phycology, 2021)

Establishment and characterization of the Bactrocera dorsalis (Diptera: Tephritidae) embryonic cell line QAU-Bd-E-2 - Gui-Ling Zheng; Jie Li; Qian-Long Yu; Bin Zhang; Xue-Meng Ding; Hui Li; Hong-Xu Zhou; Fang-Hao Wan; Chang-You Li (In Vitro Cellular & Developmental Biology - Animal, 2021)

Higher photochemical production of bromophenol by quinone-like substances extracted from humic substances using a new emodin-imprinted polymer - Hui Liu; Xiaojun Qiu; Zhi Li; Xiaomei Zhu; Bing Sun; Xiaoxing Zhang (Environmental Chemistry Letters, 2021)

Flexible reconfiguration of functional brain networks as a potential neural mechanism of creativity - Junchao Li; Natasza Orlov; Zengjian Wang; Bingqing Jiao; Yibo Wang; Huawei Xu; Hui Yang; Yingying Huang; Yan Sun; Peng Zhang; Rengui Yu; Ming Liu; et al. (Brain Imaging and Behavior, 2021)

Heterogeneity of tight sandstone reservoirs based on fractal theory: the Xu-6 member of Xujiahe Formation in Guang'an area, central Sichuan Basin - Fang Shen; Liang Yue; Ziliang Liu; Wei Yang; Kaarel Mänd; Hui Jin; Fengjie Li; Yue Zhou; Minghe Zhang; Rui Jiang (Arabian Journal of Geosciences, 2021)

Disturbance-Mediated Changes in Coral Reef Habitat Provoke a Positive Feeding Response in a Major Coral Reef Detritivore, Ctenochaetus striatus - Xianzhi Lin; Simin Hu; Yong Liu; Li Zhang; Hui Huang; Sheng Liu (Frontiers in Marine Science, 2021)
Coral reefs are undergoing global phase shifts from coral-dominated to algae-dominated stages. The negative effects of this substratum shift on the diversity and abundance of fish have been well documented, but the influence on fish feeding is less studied, which may limit a deeper understanding of trophic pathways in such a disturbed system. In this study, we investigated the feeding response of a numerically dominant fish species Ctenochaetus striatus to different substrate types, including hard coral, short algal turfs (SATs, <5 mm), and long algal turfs (LATs, >5 mm), on reefs in the South China Sea. The biomass of C. striatus showed an inverted U-shaped relationship with coral coverage and a significant positive correlation with SAT coverage ( p < 0.05), indicating that rising SAT coverage associated with moderate coral loss provoked a feeding response in C. striatus . Stomach contents of C. striatus , analyzed using high-throughput sequencing (HTS), were dominated by algal sequences (relative read abundance, RRA > 80.0%), including macroalgae, filamentous algae, and microalgae (e.g., Symbiodinium and Prorocentrum ). The sequence number and diversity of microalgae (mainly dinoflagellates) tended to be abundant (RRA 13.5–36.5%) with increased SAT cover, but brown algae sequences (RRA 17.2–57.8%) or green algae sequences (RRA > 50.7% except one site) dominated the stomach content DNA in reefs with high coral cover and high LAT or macroalgal cover, respectively. Considering the limited ability of C. striatus to remove mature algae, macroalgal DNA might be from algal debris. Our results indicate that C. striatus populations respond positively to conditions of moderate coral loss through increases in body condition identified as increased biomass. These responses are correlated to the expansion of SAT’s as coral cover declined, however, this relationship reverses if coral loss is high due to the succession of LAT’s over SAT’s and a corresponding decrease in the quality of food available. Our use of HTS has nevertheless identified the importance of detritivory in the flow of energy through reefs in the Anthropocene which are increasingly becoming depauperate in hard coral.

A new epimer of azaphilone derivative pinophilin B from the gorgonian-derived fungus Aspergillus fumigatus 14–27 - Ya-Hui Zhang; Xiao-Yue Peng; Li-Xi Feng; Hua-Jie Zhu; Fei Cao; Chang-Yun Wang (Natural Product Research, 2021)

Two new flavonoid glucosides from the fruits of Sinopodophyllum hexandrum - Yan-Jun Sun; Hao-Jie Chen; Gui-Min Xue; Hui Chen; Yan-Li Zhang; Meng Li; Kun Du; Jun-Min Wang; Wei-Sheng Feng (Natural Product Research, 2021)

Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway - Zhiheng Zhang; Wenhan Liu; Meilun Shen; Xiangying Ma; Rouqian Li; Xiaodi Jin; Hui Bai; Li Gao (Molecular Neurobiology, 2021)

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

Fusarium solani G6, a novel vitexin-producing endophytic fungus: characterization, yield improvement and osteoblastic proliferation activity - Pei-jia Tang; Zhi-hui Zhang; Li-li Niu; Cheng-bo Gu; Wen-yi Zheng; Hai-chao Cui; Xiao-han Yuan (Biotechnology Letters, 2021)

Transforming growth factor β as a possible independent factor in chronic hepatitis B - Ming-hui Li; Yao Lu; Fang-fang Sun; Qi-qi Chen; Lu Zhang; Hui-hui Lu; Zhan Zeng; Wei Yi; Yao Xie (Archives of Virology, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

The Role of lncRNA TUG1 in the Parkinson Disease and Its Effect on Microglial Inflammatory Response - Jiang Cheng; Yangyang Duan; Fengting Zhang; Jin Shi; Hui Li; Feng Wang; Haining Li (NeuroMolecular Medicine, 2021)

DNA Methyltransferase 1 Is Dysregulated in Parkinson’s Disease via Mediation of miR-17 - Hong-Qiu Zhang; Jian-Yong Wang; Zhao-Feng Li; Lei Cui; Shi-Shi Huang; Lan-Bing Zhu; Yue Sun; Rui Yang; Hui-Hui Fan; Xiong Zhang; Jian-Hong Zhu (Molecular Neurobiology, 2021)

Seismic signal characteristics and interpretation of the 2020 “6.17” Danba landslide dam failure hazard chain process - Yan Yan; Yifei Cui; Dingzhu Liu; Hui Tang; Yongjian Li; Xin Tian; Lei Zhang; Sheng Hu (Landslides, 2021)

Roles of bulk and rhizosphere denitrifying bacteria in denitrification from paddy soils under straw return condition - Ning Wang; Ya-Hui Zhao; Jian-Guang Yu; Li-Hong Xue; Hong-Bo Li; Lin-Zhang Yang (Journal of Soils and Sediments, 2021)

L-3-n-Butylphthalide Effectively Improves the Glymphatic Clearance and Reduce Amyloid-β Deposition in Alzheimer’s Transgenic Mice - Bo Zhang; Wei Li; Youguang Zhuo; Hui Xiang; Wenfeng Li; Hongying Liu; Longchang Xie; Qingchun Gao; Sheng Tan (Journal of Molecular Neuroscience, 2021)

Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis - Gai Gao; Zhishen Xie; Er-wen Li; Yong Yuan; Yu Fu; Pan Wang; Xiaowei Zhang; Yonghui Qiao; Jiangyan Xu; Christian Hölscher; Hui Wang; Zhenqiang Zhang (Journal of Natural Medicines, 2021)

A rapid and accurate method for identifying sexuality of Indarbela obliquifasciata Mell (Lepidoptera, Metarbelidae) adults and pupae - Li-Zhi Huo; Long-Hua Sun; Jing-Ai Zhang; Chao Wu; Ya-Hui Hou; Yong-Yue Wang; Zhi-Jie Li; Jia-Ru Deng; Si-Meng Yang; Ke-Ke Bi (International Journal of Tropical Insect Science, 2021)

Intraspecific recurrent selection in V. vinifera: an effective method for breeding of high quality, disease-, cold-, and drought -resistant grapes - Zhi-Lei Wang; Ting-Ting Xue; Fei-Fei Gao; Liang Zhang; Xing Han; Ying Wang; Miao Hui; Dong Wu; Hua Li; Hua Wang (Euphytica, 2021)

A review on mechanism of biomineralization using microbial-induced precipitation for immobilizing lead ions - Bing Shan; Ruixia Hao; Hui Xu; Jiani Li; Yinhuang Li; Xiyang Xu; Junman Zhang (Environmental Science and Pollution Research, 2021)

Lipopeptide production by Bacillus atrophaeus strain B44 and its biocontrol efficacy against cotton rhizoctoniosis - Li Chen; Hui Zhang; Sifeng Zhao; Benchun Xiang; Zhaoqun Yao (Biotechnology Letters, 2021)

Herbivore identity and intensity interact to influence plant metabolic response to herbivory - Sufeng Pan; Jing Zhang; Hui Pan; Kai Li; Jie Wu (Arthropod-Plant Interactions, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Physiological determinants of biogeography: The importance of metabolic depression to heat tolerance - Ming‐ling Liao; Gao‐yang Li; Jie Wang; David J. Marshall; Tin Yan Hui; Shu‐yang Ma; Yi‐min Zhang; Brian Helmuth; Yun‐wei Dong (Global Change Biology, 2021)
A quantitative understanding of physiological thermal responses is vital for forecasting species distributional shifts in response to climate change. Many studies have focused on metabolic rate as a global metric for analyzing the sublethal effects of changing environments on physiology. Thermal performance curves (TPCs) have been suggested as a viable analytical framework, but standard TPCs may not fully capture physiological responses, due in part to failure to consider the process of metabolic depression. We derived a model based on the nonlinear regression of biological temperature‐dependent rate processes and built a heart rate data set for 26 species of intertidal molluscs distributed from 33°S to ~40°N. We then calculated physiological thermal performance limits with continuous heating using , the temperature at which heart rate is decreased to 50% of the maximal rate, as a more realistic measure of upper thermal limits. Results indicate that heat‐induced metabolic depression of cardiac performance is a common adaptive response that allows tolerance of harsh environments. Furthermore, our model accounted for the high inter‐individual variability in the shape of cardiac TPCs. We then used these TPCs to calculate physiological thermal safety margins (pTSM), the difference between the maximal operative temperature (95th percentile of field temperatures) and of each individual. Using pTSMs, we developed a physiological species distribution model (pSDM) to forecast future geographic distributions. pSDM results indicate that climate‐induced species range shifts are potentially less severe than predicted by a simple correlative SDM. Species with metabolic depression below the optimum temperature will be more thermal resistant at their warm trailing edges. High intraspecific variability further suggests that models based on species‐level vulnerability to environmental change may be problematic. This multi‐scale, mechanistic understanding that incorporates metabolic depression and inter‐individual variability in thermal response enables better predictions about the relationship between thermal stress and species distributions.

Natural abundance of 13 C and 15 N provides evidence for plant–soil carbon and nitrogen dynamics in a N‐fertilized meadow - Ruzhen Wang; Josep Peñuelas; Tian Li; Heyong Liu; Hui Wu; Yuge Zhang; Jordi Sardans; Yong Jiang (Ecology, 2021)
Natural abundance of carbon (C) and nitrogen (N) stable isotope ratios (δ 13 C and δ 15 N) has been used to indicate ecosystem C and N status and cycling; however, use of this approach to infer plant and microbial N preference under projected ecosystem N enrichment is limited. Here, we investigated natural abundance δ 13 C and δ 15 N of five dominant plant species, and soil δ 15 N of microbial biomass and available N forms under N addition in a meadow steppe. Additional N, applied as urea, led to decreases in δ 15 N of soil NO 3 − (δ 15 N nitrate , from 3.0 to 0.4‰) and increases in δ 15 N of soil (δ 15 N ammonium , from −1.3 to 11‰) and dissolved organic N (δ 15 N DON , from 8.5 to 15‰) that reflected increased net nitrification rates, a possible increase in NH 3 volatilization, and greater availability of the three N forms. An overall increase in δ 15 N of soil total N (δ 15 N TN ) from 7.1 to 7.9‰ indicated accelerated and greater openness of soil N cycling that was also partially revealed by enhanced net N mineralization rates. Plant δ 15 N, which ranged from −1.8 to 2.1‰, generally decreased with N addition, indicating a greater reliance on soil NO 3 − under N‐enrichment conditions. Nitrogen addition decreased δ 15 N of microbial biomass N (from 14 to 2.8‰), possibly because of a shift in preferential N form (DON to ), that indicated a convergence of plant and microbial preferential N forms and an increase in plant–microbial N competition. Microbes were thus more flexible than plants in the use of different forms of N. Addition of N decreased plant litter δ 13 C, whereas plant species δ 13 C remained unaffected, likely because of a shift in the abundance of dominant species with a greater proportion of biomass coming from δ 13 C‐depleted species. Enrichment factor (the difference in plant δ 15 N relative to δ 15 N TN ) of four nonlegume species was negatively related to soil inorganic N availability, net nitrification rate, and net N mineralization rate, and was proven to be a good indicator of ecosystem N status. Our study highlights the importance of natural abundance of 15 N as an indicator of plant–microbial N competition and ecosystem N cycling in meadow steppe grasslands under projected ecosystem N enrichment.

Gene co-expression network analysis of the heat-responsive core transcriptome identifies hub genes in Brassica rapa - Lixin Yue; Guoliang Li; Yun Dai; Xiao Sun; Fei Li; Shifan Zhang; Hui Zhang; Rifei Sun; Shujiang Zhang (Planta, 2021)

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

Taste Masking Study Based on an Electronic Tongue: the Formulation Design of 3D Printed Levetiracetam Instant-Dissolving Tablets - Zengming Wang; Jingru Li; Xiaoxuan Hong; Xiaolu Han; Boshi Liu; Xianfu Li; Hui Zhang; Jing Gao; Nan Liu; Xiang Gao; Aiping Zheng (Pharmaceutical Research, 2021)
Purpose Proper taste-masking formulation design is a critical issue for instant-dissolving tablets (IDTs). The purpose of this study is to use the electronic tongue to design the additives of the 3D printed IDTs to improve palatability. Methods A binder jet 3D printer was used to prepare IDTs of levetiracetam. A texture analyzer and dissolution apparatus were used to predict the oral dispersion time and in vitro drug release of IDTs, respectively. The palatability of different formulations was investigated using the ASTREE electronic tongue in combination with the design of experiment and a model for masking bitter taste. Human gustatory sensation tests were conducted to further evaluate the credibility of the results. Results The 3D printed tablets exhibited rapid dispersion (<30 s) and drug release (2.5 min > 90%). The electronic tongue had an excellent ability of taste discrimination, and levetiracetam had a good linear sensing performance based on a partial least square regression analysis. The principal component analysis was used to analyze the signal intensities of different formulations and showed that 2% sucralose and 0.5% spearmint flavoring masked the bitterness well and resembled the taste of corresponding placebo. The results of human gustatory sensation test were consistent with the trend of the electronic tongue evaluation. Conclusions Owing to its objectivity and reproducibility, this technique is suitable for the design and evaluation of palatability in 3D printed IDT development.

Spatial prediction of soil calcium carbonate content based on Bayesian maximum entropy using environmental variables - Mei Shan; Shuang Liang; Hongchen Fu; Xiaoli Li; Yu Teng; Jingwen Zhao; Yaxin Liu; Chen Cui; Li Chen; Hai Yu; Shunbang Yu; Yanling Sun; et al. (Nutrient Cycling in Agroecosystems, 2021)

New insights into the fine-scale history of western–eastern admixture of the northwestern Chinese population in the Hexi Corridor via genome-wide genetic legacy - Hongbin Yao; Mengge Wang; Xing Zou; Yingxiang Li; Xiaomin Yang; Ailin Li; Hui-Yuan Yeh; Peixin Wang; Zheng Wang; Jingya Bai; Jianxin Guo; Jinwen Chen; et al. (Molecular Genetics and Genomics, 2021)

Design, synthesis and evaluation of dihydrotriazine derivatives-bearing 5-aryloxypyrazole moieties as antibacterial agents - Tian-Yi Zhang; Chun-Shi Li; Ming-Yue Cui; Xue-Qian Bai; Jiang-Hui Chen; Ze-Wen Song; Bo Feng; Xue-Kun Liu (Molecular Diversity, 2021)

KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity - Hui Li; Yaqian Weng; Luying Lai; Hongyi Lei; Shiyuan Xu; Yang Zhang; Le Li (Molecular and Cellular Biochemistry, 2021)

RET compound inheritance in Chinese patients with Hirschsprung disease: lack of penetrance from insufficient gene dysfunction - Qian Jiang; Yang Wang; Yang Gao; Hui Wang; Zhen Zhang; Qi Li; Shuhua Xu; Wei Cai; Long Li (Human Genetics, 2021)

Delineating the organization of projection neuron subsets in primary visual cortex with multiple fluorescent rabies virus tracing - Liang Li; Yajie Tang; Leqiang Sun; Jinsong Yu; Siheng Zhang; Hui Gong; Hannah C. Webber; Xiaoyu Zhang; Zhe Hu; Xiangning Li; Khaista Rahman; Xiangwei Shi; et al. (Brain Structure and Function, 2021)

Vegetation dynamics and climate variability over the past 2000 years inferred from Son Kul marsh in the western Tianshan Mountains - Dong-liang Zhang; Yao-ming Li; Kai-hui Li; Xue-xi Ma; Yun-peng Yang (Journal of Mountain Science, 2021)

Dynamic changes in the genetic parameters of growth traits with age and their associations with heterosis in hybrid Liriodendron - Hui Xia; Weijie Si; Ziyuan Hao; Weiping Zhong; Shenghua Zhu; Zhonghua Tu; Chengge Zhang; Huogen Li (Tree Genetics & Genomes, 2021)

Flavonoids improve drought tolerance of maize seedlings by regulating the homeostasis of reactive oxygen species - Baozhu Li; Ruonan Fan; Guiling Sun; Ting Sun; Yanting Fan; Shenglong Bai; Siyi Guo; Shiquan Huang; Jiong Liu; Hui Zhang; Pengtao Wang; Xiaohong Zhu; et al. (Plant and Soil, 2021)
Background and aims As drought threatens the yield and quality of maize ( Zea mays L.), it is important to dissect the molecular basis of maize drought tolerance. Flavonoids, participate in the scavenging of oxygen free radicals and alleviate stress-induced oxidative damages. This study aims to dissect the function of flavonoids in the improvement of maize drought tolerance. Methods Using far-infrared imaging screening, we previously isolated a drought overly insensitivity ( doi ) mutant from an ethyl methanesulfonate (EMS)-mutagenized maize library and designated it as doi57 . In this study, we performed a physiological characterization and transcriptome profiling of doi57 in comparison to corresponding wild-type B73 under drought stress. Results Under drought stress, doi57 seedlings displayed lower leaf-surface temperature (LST), faster water loss, and better performance in growth than B73. Transcriptome analysis reveals that key genes involved in flavonoid biosynthesis are enriched among differentially expressed genes in doi57 . In line with these results, more flavonols and less hydrogen peroxide (H 2 O 2 ) were accumulated in guard cells of doi57 than in those of B73 with the decrease of soil water content (SWC). Moreover, the capacity determined from doi57 seedling extracts to scavenge oxygen free radicals was more effective than that of B73 under the drought treatment. Additionally, doi57 seedlings had higher photosynthetic rates, stomatal conductance, transpiration rates, and water use efficiency than B73 exposed to drought stress, resulting in high biomass and greater root/shoot ratios in doi57 mutant plants. Conclusion Flavonoids may facilitate maize seedling drought tolerance by lowering drought-induced oxidative damage as well regulating stomatal movement.

A Role of the Podoplanin-CLEC-2 Axis in Promoting Inflammatory Response After Ischemic Stroke in Mice - Danyang Meng; Xiaohua Ma; Hui Li; Xuechun Wu; Yongjun Cao; Zhigang Miao; Xia Zhang (Neurotoxicity Research, 2021)

Divergent Projection Patterns Revealed by Reconstruction of Individual Neurons in Orbitofrontal Cortex - Junjun Wang; Pei Sun; Xiaohua Lv; Sen Jin; Anan Li; Jianxia Kuang; Ning Li; Yadong Gang; Rui Guo; Shaoqun Zeng; Fuqiang Xu; Yu-Hui Zhang (Neuroscience Bulletin, 2021)

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

Gas Flow Characteristics and Optimization of Gas Drainage Borehole Layout in Protective Coal Seam Mining: A Case Study from the Shaqu Coal Mine, Shanxi Province, China - Zhiheng Cheng; Hui Pan; Quanle Zou; Zhenhua Li; Liang Chen; Jialin Cao; Kun Zhang; Yongguo Cui (Natural Resources Research, 2021)

Clinical and microbiological characteristics of adults with hospital-acquired pneumonia: a 10-year prospective observational study in China - Yuyao Yin; Chunjiang Zhao; Henan Li; Longyang Jin; Qi Wang; Ruobing Wang; Yawei Zhang; Jiangang Zhang; Hui Wang; Chunxia Yang; Bin Cao; Yingmei Liu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Morphology and composition of particles emitted from conventional and alternative fuel vehicles - Zhenzhen Lu; Shunxi Deng; Xi Liu; Lihui Huang; Ruixu Zhang; Hui Song; Guanghua Li (Environmental Science and Pollution Research, 2021)

Short Communication: Effects of Dietary Selenium Supplementation on Selenium Deposition and Antioxidant Status in Postpartum Mice - Zhen-Nan Wang; Hui Li; He Tang; Shu-Jiu Zhang; Mirielle Pauline; Chong-Liang Bi (Biological Trace Element Research, 2021)

Males and females of a polygamous songbird respond differently to mating opportunities - Jia Zheng; Jan Komdeur; Tamás Székely; Maaike A. Versteegh; Donglai Li; Hui Wang; Zhengwang Zhang (Behavioral Ecology and Sociobiology, 2021)

Comprehensive evaluation of shaped charge blasting effect of rock roadway based on entropy-weighted matter-element extension model - Huiyao Zhang; Xiantang Zhang; Hui Yu; Juan Li; Hongmin Zhou; Dan Li (Arabian Journal of Geosciences, 2021)

Spatial environment design and comfort simulation of high-latitude building bottom based on geological conditions - Hui Liu; Nan Zhang; Ning Li; Ping Zhang; Xiujuan Jiang (Arabian Journal of Geosciences, 2021)

Rare taxa maintain the stability of crop mycobiomes and ecosystem functions - Chao Xiong; Ji‐Zheng He; Brajesh K. Singh; Yong‐Guan Zhu; Jun‐Tao Wang; Pei‐Pei Li; Qin‐Bing Zhang; Li‐Li Han; Ju‐Pei Shen; An‐Hui Ge; Chuan‐Fa Wu; Li‐Mei Zhang (Environmental Microbiology, 2021)
Summary Plants harbour highly diverse mycobiomes which sustain essential functions for host health and productivity. However, ecological processes that govern the plant–mycobiome assembly, interactions and their impact on ecosystem functions remain poorly known. Here we characterized the ecological role and community assembly of both abundant and rare fungal taxa along the soil–plant continuums (rhizosphere, phyllosphere and endosphere) in the maize–wheat/barley rotation system under different fertilization practices at two contrasting sites. Our results indicate that mycobiome assembly is shaped predominantly by compartment niche and host species rather than by environmental factors. Moreover, crop‐associated fungal communities are dominated by few abundant taxa mainly belonging to Sordariomycetes and Dothideomycetes, while the majority of diversity within mycobiomes are represented by rare taxa. For plant compartments, the abundant sub‐community is mainly determined by stochastic processes. In contrast, the rare sub‐community is more sensitive to host selection and mainly governed by deterministic processes. Furthermore, our results demonstrate that rare taxa play an important role in fungal co‐occurrence network and ecosystem functioning like crop yield and soil enzyme activities. These results significantly advance our understanding of crop mycobiome assembly and highlight the key role of rare taxa in sustaining the stability of crop mycobiomes and ecosystem functions.

Essential oil from Artemisia annua aerial parts: composition and repellent activity against two storage pests - Hong Liu; Shan-Shan Guo; Li Lu; Dian Li; Jun Liang; Zhong-Hui Huang; Yan-Mei Zhou; Wen-Juan Zhang; Shushan Du (Natural Product Research, 2021)

Determination and risk assessment of perfluorinated alkylated substances (PFASs) in pork liver from mainland, China - Juan Zhang; Lu Qiao; Hui Li; Shuming Yang; Ailiang Chen (Food Additives & Contaminants: Part A, 2021)

Seismic wave equations in tight oil/gas sandstone media - Jinghuai Gao; Weimin Han; Yanbin He; Haixia Zhao; Hui Li; Yijie Zhang; Zongben Xu (Science China Earth Sciences, 2021)

Effects of simulated drought stress on carotenoid contents and expression of related genes in carrot taproots - Rong-Rong Zhang; Ya-Hui Wang; Tong Li; Guo-Fei Tan; Jian-Ping Tao; Xiao-Jun Su; Zhi-Sheng Xu; Yong-Sheng Tian; Ai-Sheng Xiong (Protoplasma, 2021)

Unraveling Physiological and Metabolomic Responses Involved in Phlox subulata L. Tolerance to Drought Stress - Yan Xiong; Yanting Qu; Hui Han; Fei Chen; Li Li; Huanwei Tang; Daidi Che; Xing Zhang (Plant Molecular Biology Reporter, 2021)

Analysis of loess landslide mechanism and numerical simulation stabilization on the Loess Plateau in Central China - Wan-li Xie; Qianyi Guo; Jason Y. Wu; Ping Li; Hui Yang; Maosheng Zhang (Natural Hazards, 2021)
Loess landslides have complicated deformation mechanisms. Accurately describing the internal failure deformation of loess landslides and establishing a theoretical method of landslide instability evaluation for the prevention of subsequent landslides have become important topics in western development project construction in China. This paper presents a case study of the Zhonglou Mountain landslide in Shaanxi Province, China. Based on field investigation results, a two-dimensional stability analysis model was constructed using the finite element method. Taking the deformation characteristics of the landslide as the research basis, the distribution laws of the displacement, stress, and shear strain of this landslide were identified with the strength reduction finite element numerical simulation method. Additionally, the safety factor was evaluated under normal and storm conditions. The numerical simulation results show that the horizontal tensile stress of the landslide was mainly distributed in the middle and upper parts of the landslide under normal conditions, while the vertical tensile stress was distributed near the sliding surface. Under heavy rainfall, the sliding force increased, and the anti-sliding force and anti-sliding section decreased; the location of the maximum shear strain shifted down from the middle and upper parts of the landslide body to the area with a shear crack, and the plastic shear strain area expanded along nearly the entire the sliding surface, leading to the occurrence of a landslide. Thus, the use of anti-slide piles to stabilize the landslide was proposed and tested. Monitoring points were arranged along the sliding surface to evaluate the displacement, stress, and strain responses. The on-site observation results agreed with the modeling results. The use of anti-slide piles was demonstrated to be an effective stabilization method for the Zhonglou Mountain landslide.

Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling - Li Zhang; Lu Wang; Han Xiao; Hui Gan; Hui Chen; Shuyue Zheng; Dan Jian; Xuan Zhai; Ning Jiang; Zhao Jing; Ping Liang (Journal of Molecular Medicine, 2021)

Efficient Editing of an Adenoviral Vector Genome with CRISPR/Cas9 - Qiang Li; Hui Wang; Chen-yu Gong; Zhao Chen; Jia-xing Yang; Hong-wei Shao; Wen-feng Zhang (Indian Journal of Microbiology, 2021)

Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease - Meng Zhang; Mengying Wang; Hui Wang; Ying Zhang; Zhengzheng Li; Yiping Feng; Yinan Liu; Yue Liu; Yucheng Liao; Wenjun Wang; Qian Fang; Jinghong Chen (Biological Trace Element Research, 2021)

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China - Qing-Hai Wang; Xiang-Ying Li; Ting-Ting Xu; Meng-Ai Zhang; Yu-Hui Yang; Pei-Bo Feng; Su-Su Fan; Zhen-Yu Liu (Journal of General Plant Pathology, 2021)

Suppression of miR-4463 promotes phenotypic switching in VSMCs treated with Ox-LDL - Xueqin Wang; Hui Li; Yuetian Zhang; Qi Liu; Xiaolei Sun; Xuemei He; Qian Yang; Ping Yuan; Xiangyu Zhou (Cell and Tissue Research, 2021)

QTL mapping for foxtail millet plant height in multi-environment using an ultra-high density bin map - Qiang He; Hui Zhi; Sha Tang; Lu Xing; Suying Wang; Haigang Wang; Aiying Zhang; Yuhui Li; Ming Gao; Haijin Zhang; Guoqiu Chen; Shutao Dai; et al. (Theoretical and Applied Genetics, 2021)

GmNAC06, a NAC domain transcription factor enhances salt stress tolerance in soybean - Ming Li; Rui Chen; Qiyan Jiang; Xianjun Sun; Hui Zhang; Zheng Hu (Plant Molecular Biology, 2021)
Key message We found GmNAC06 plays an important role in salt stress responses through the phenotypic, physiological and molecular analyses of OE, VC, and Mutant composite soybean. Abstract Salinization affects 20% of all cultivated land worldwide because of the high salinity of irrigation water and the excessive use of water, and this amount is increasing daily. NAC (NAM, ATAF, and CUC) have been found to be involved in salt stress. In this study, a soybean NAC gene, GmNAC06 (Glyma06g21020.1), was cloned and functionally characterized. The results of expression analysis suggested that salt stress could influence the expression level of GmNAC06 . The subcellular localization analysis results suggested that GmNAC06 may function as a transcription factor. Under salt stress, the overexpression technology combined with CRISPR-Cas9 system found that GmNAC06 could cause the accumulation of proline and glycine betaine to alleviate or avoid the negative effects of ROS; similarly, it could control the Na + /K + ratios in hairy roots to maintain ionic homeostasis. The fresh weight of the transgenic hairy roots and the histochemical ROS staining of wild leaves suggested that transgenic hairy roots influence the function of wild leaves under salt stress conditions. Moreover, the expression levels of GmUBC2 and GmHKT1 were higher in the GmNAC06 hairy roots than in the control. Thus, the overexpression of GmNAC06 in hairy roots notably causes an entire composite plant to exhibit salt tolerance. The phenotype of composite soybean plants and transgenic Arabidopsis plants suggest that GmNAC06 plays a role in response to salt stress and could be useful in generating salt tolerant transgenic crops.

Comprehensive analysis of coding sequence architecture features and gene expression in Arachis duranensis - Shuwei Dong; Long Zhang; Wenhui Pang; Yongli Zhang; Chang Wang; Zhenyi Li; Lichao Ma; Wei Tang; Guofeng Yang; Hui Song (Physiology and Molecular Biology of Plants, 2021)

Using Composite Phenotypes to Reveal Hidden Physiological Heterogeneity in High-Altitude Acclimatization in a Chinese Han Longitudinal Cohort - Yi Li; Yanyun Ma; Kun Wang; Menghan Zhang; Yi Wang; Xiaoyu Liu; Meng Hao; Xianhong Yin; Meng Liang; Hui Zhang; Xiaofeng Wang; Xingdong Chen; et al. (Phenomics, 2021)
Altitude acclimatization is a human physiological process of adjusting to the decreased oxygen availability. Since several physiological processes are involved and their correlations are complicated, the analyses of single traits are insufficient in revealing the complex mechanism of high-altitude acclimatization. In this study, we examined these physiological responses as the composite phenotypes that are represented by a linear combination of physiological traits. We developed a strategy that combines both spectral clustering and partial least squares path modeling (PLSPM) to define composite phenotypes based on a cohort study of 883 Chinese Han males. In addition, we captured 14 composite phenotypes from 28 physiological traits of high-altitude acclimatization. Using these composite phenotypes, we applied k-means clustering to reveal hidden population physiological heterogeneity in high-altitude acclimatization. Furthermore, we employed multivariate linear regression to systematically model (Models 1 and 2) oxygen saturation (SpO 2 ) changes in high-altitude acclimatization and evaluated model fitness performance. Composite phenotypes based on Model 2 fit better than single trait-based Model 1 in all measurement indices. This new strategy of using composite phenotypes may be potentially employed as a general strategy for complex traits research such as genetic loci discovery and analyses of phenomics.

NDRG2 is expressed on enteric glia and altered in conditions of inflammation and oxygen glucose deprivation/reoxygenation - Yuxin Zhang; Hui Gao; Na Li; Haiqing Chang; Bo Cheng; Yansong Li; Jiwen Miao; Shuang Li; Qiang Wang (Journal of Molecular Histology, 2021)

Stability Control of the Equipment Recovery Passage in a Fully Mechanized Longwall Mining: Case Study - Zhiyi Zhang; Hui Chen; Dongfa Li; Zhiqiang Zhang (Geotechnical and Geological Engineering, 2021)

Mass balance reconstruction for Shiyi Glacier in the Qilian Mountains, Northeastern Tibetan Plateau, and its climatic drivers - Hui Zhang; Zhongqin Li; Ping Zhou (Climate Dynamics, 2021)

Simultaneously decreased temporal variability and enhanced variability-strength coupling of emotional network connectivities are related to positive symptoms in patients with schizophrenia - Yanjia Deng; Shuguang Han; Dongliang Cheng; Hui Li; Bin Zhang; Youyong Kong; Yong Lin; Yingjia Li; Ge Wen; Kai Liu (Brain Imaging and Behavior, 2021)

Insights into the Role of Magnesium Ions in Affecting Osteogenic Differentiation of Mesenchymal Stem Cells - Tiantian Qi; Jian Weng; Fei Yu; Weifei Zhang; Guoqing Li; Haotian Qin; Zhen Tan; Hui Zeng (Biological Trace Element Research, 2021)

Selenium Plays an Anti-Inflammatory Role by Regulation NLRP3 Inflammasome in Staphylococcus aureus-Infected Mouse Mammary Gland - Chong-Liang Bi; Shu-Jiu Zhang; Yi-Zhao Shen; Mirielle Pauline; Hui Li; He Tang (Biological Trace Element Research, 2021)

Numerical simulation of seasonal snow in Tianshan Mountains - Yan-run Ren; Yao-nan Zhang; Jian-sheng Hao; Yong-ping Shen; Guo-hui Zhao; Cong Li (Journal of Mountain Science, 2021)

Downregulation of miR-296-3p by highly pathogenic porcine reproductive and respiratory syndrome virus activates the IRF1/TNF-α signaling axis in porcine alveolar macrophages - Yanbing Zhang; Xiao Xiang; Yan Lu; Hui Li; Abdul Wahaab; Mona Sharma; Ke Liu; Jianchao Wei; Zongjie Li; Donghua Shao; Beibei Li; Zhiyong Ma; et al. (Archives of Virology, 2021)

Effects of granularity and clay content on the permeability of the fault core in the Renlou coal mine in China: implications for underground water inrush - Hui Gui; Jinpeng Xu; Yudong Zhang; Yang Li (Arabian Journal of Geosciences, 2021)

Building the carbonate pore-type classifier for well logging via the blended training dataset - Bonan Li; Wenpeng Si; Hui Shen; Xuebing Zhang (Acta Geophysica, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

The Effect of Composting on the Multiple Heavy Metals in the River Sediment Investigated by Multivariate Analysis - Yaoning Chen; Yanrong Chen; Yuanping Li; Yihuan Liu; Daoli Zhang; Yanxin Wu; Hui Li; Fangting Xu; Meiling Li (Water, Air, & Soil Pollution, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Partial recovery of disturbed V-J pairing profiles of T-cell receptor in people living with HIV receiving long-term antiretroviral therapy - Guoli Li; Jiarui Li; Henghui Zhang; Yu Zhang; Di Liu; Yu Hao; Junyan Han; Juan Du; Liuluan Zhu; Yongqin Zeng; Bei Li; Rui Li; et al. (Science China Life Sciences, 2021)

Early-Life Multiple Sevoflurane Exposures Alleviate Long-term Anxiety-Like Behaviors in Mice via the proBDNF/ERK Pathway - Ru-Yi Luo; Cong Luo; Feng Zhong; Wei-Yun Shen; Hui Li; Yan-Ling Zhang; Ru-Ping Dai (Molecular Neurobiology, 2021)

A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice - Yuncheng Pan; Xi Yang; Feng Zhang; Siyuan Chen; Zixue Zhou; Hao Yin; Hui Ma; Lingyue Shang; Jialin Yang; Guoqing Li; Yingchen Wang; Li Jin; et al. (Molecular Genetics and Genomics, 2021)

Advances in intervention methods and brain protection mechanisms of in situ and remote ischemic postconditioning - Chun-Yan Li; Wei Ma; Kuang-Pin Liu; Jin-Wei Yang; Xian-Bin Wang; Zhen Wu; Tong Zhang; Jia-Wei Wang; Wei Liu; Jie Liu; Yu Liang; Xing-Kui Zhang; et al. (Metabolic Brain Disease, 2021)

A plant virus mediates interspecific competition between its insect vectors in Capsicuum annuum - Yong Chen; Xue Zheng; Hui Wei; Yong-Dui Chen; Kuan-Yu Zheng; Ye Mu; Xing-Yue Zhao; Li-Hua Zhao; Yu-Lin Gao; Li-Min Zheng; Jie Zhang (Journal of Pest Science, 2021)

High bioremediation potential of strain Chenggangzhangella methanolivorans CHL1 for soil polluted with metsulfuron-methyl or tribenuron-methyl in a pot experiment - Ting-Ting Yang; Hui-Wen Zhang; Jian Wang; Xin-Yu Li; Xu Li; Zhen-Cheng Su (Environmental Science and Pollution Research, 2021)

Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice - Hehuan Lai; Tingting Nie; Yitong Zhang; Ying Chen; Jiaqi Tao; Tingting Lin; Tangdong Ge; Fenglan Li; Hui Li (Biological Trace Element Research, 2021)

Improving the observation and prediction capabilities for Arctic marine environment: from the perspective of Arctic Shipping - Hui Wang; Qizhen Sun; Lin Zhang; Xi Liang; Qinghua Yang; Na Liu; Chunhua Li; Qingsheng Liu; Bingrui Li; Qian Feng; Xiao Cheng; Yi Yu (Acta Oceanologica Sinica, 2021)

Phosphorus addition decreases microbial residual contribution to soil organic carbon pool in a tropical coastal forest - Ye Yuan; Yue Li; Zhijian Mou; Luhui Kuang; Wenjia Wu; Jing Zhang; Faming Wang; Dafeng Hui; Josep Peñuelas; Jordi Sardans; Hans Lambers; Jun Wang; et al. (Global Change Biology, 2021)
The soil nitrogen (N) and phosphorus (P) availability often constrains soil carbon (C) pool, and elevated N deposition could further intensify soil P limitation, which may affect soil C cycling in these N‐rich and P‐poor ecosystems. Soil microbial residues may not only affect soil organic carbon (SOC) pool but also impact SOC stability through soil aggregation. However, how soil nutrient availability and aggregate fractions affect microbial residues and the microbial residue contribution to SOC is still not well understood. We took advantage of a 10‐year field fertilization experiment to investigate the effects of nutrient additions, soil aggregate fractions, and their interactions on the concentrations of soil microbial residues and their contribution to SOC accumulation in a tropical coastal forest. We found that continuous P addition greatly decreased the concentrations of microbial residues and their contribution to SOC, whereas N addition had no significant effect. The P‐stimulated decreases in microbial residues and their contribution to SOC were presumably due to enhanced recycling of microbial residues via increased activity of residue‐decomposing enzymes. The interactive effects between soil aggregate fraction and nutrient addition were not significant, suggesting a weak role of physical protection by soil aggregates in mediating microbial responses to altered soil nutrient availability. Our data suggest that the mechanisms driving microbial residue responses to increased N and P availability might be different, and the P‐induced decrease in the contribution of microbial residues might be unfavorable for the stability of SOC in N‐rich and P‐poor tropical forests. Such information is critical for understanding the role of tropical forests in the global carbon cycle.

Antibody response and therapy in COVID-19 patients: what can be learned for vaccine development? - Ligong Lu; Hui Zhang; Meixiao Zhan; Jun Jiang; Hua Yin; Danielle J. Dauphars; Shi-You Li; Yong Li; You-Wen He (Science China Life Sciences, 2020)

Uncovering the mysterious identity of Taisui—an old Chinese folk legend - Erwei Li; Jinwei Ren; Qian Chen; Hanxing Zhang; Bin Lin; Hui Zhang; Shumin Zhang; Xiaoling Zhang; Lei Cai; Xingzhong Liu (Science China Life Sciences, 2020)

Inland fisheries development versus aquatic biodiversity conservation in China and its global implications - Hui Zhang; Jinming Wu; Harry Gorfine; Xiujuan Shan; Li Shen; Haile Yang; Hao Du; Junyi Li; Chengyou Wang; Qiong Zhou; Zhigang Liu; Myounghee Kang; et al. (Reviews in Fish Biology and Fisheries, 2020)

ADP-ribosylation factors improve biomass yield and salinity tolerance in transgenic switchgrass (Panicum virgatum L.) - Cong Guan; Xue Li; Dan-Yang Tian; Hua-Yue Liu; Hui-Fang Cen; Million Tadege; Yun-Wei Zhang (Plant Cell Reports, 2020)

Correction to: Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Chang-Qi Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Genotype and Phenotype Correlations for TBL1XR1 in Neurodevelopmental Disorders - Yingting Quan; Qiumeng Zhang; Meilin Chen; Huidan Wu; Jianjun Ou; Yidong Shen; Kuokuo Li; Guanglei Xun; Jingping Zhao; Zhengmao Hu; Kun Xia; Hui Guo (Journal of Molecular Neuroscience, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Models and measurements of seven years of evapotranspiration on a high elevation site on the Central Tibetan Plateau - Li-hui Wang; Xiao-bo He; Jakob F. Steiner; Dong-wei Zhang; Jin-kui Wu; Shao-yong Wang; Yong-jian Ding (Journal of Mountain Science, 2020)

LncRNA NEAT1 accelerates renal mesangial cell injury via modulating the miR-146b/TRAF6/NF-κB axis in lupus nephritis - Li-Hua Zhang; Bin Xiao; Miao Zhong; Qiao Li; Jian-Ying Chen; Jie-Rou Huang; Hui Rao (Cell and Tissue Research, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Groundwater resources survey of tongchuan city using the audio magnetotelluric method - Zhi-min Xu; Jing-tian Tang; Guang Li; Hui-Cui Xin; Zhang-jian Xu; Xin-ping Tan; Jin Li (Applied Geophysics, 2020)

On the responses of soil layers surrounding a suction bucket under cyclic loads - Bin Zhang; Huan-long Kang; Xu-hui Zhang; Xiao-bing Lu; Yu-tao Li (Marine Georesources & Geotechnology, 2020)

Chemical composition, antimicrobial activity and antioxidant activity of Litsea cubeba essential oils in different months - Qi-Hui She; Wen-Shuang Li; Yuan-Yuan Jiang; Yi-Chao Wu; Yong-Hong Zhou; Li Zhang (Natural Product Research, 2020)

Solanrubiellin A, a hydroanthraquinone dimer with antibacterial and cytotoxic activity from Solanum lyratum - Hui Chen; Kun Du; Yan-Jun Sun; Zhi-You Hao; Yan-Li Zhang; Jiang Bai; Qing-Hua Wang; Hai-Yu Hu; Wei-Sheng Feng (Natural Product Research, 2020)

Petrogenesis of post-collisional magmatism at the Carboniferous–Permian boundary in central Inner Mongolia, NE China: insights into when the Hegenshan Ocean closed? - Lu Lu; Yong Qin; Kai-Jun Zhang; Chun-Yuan Han; Zhuang-Fu Li; Tao Wei; Zheng-Hui Qu; Yong-Zhong Xu (International Geology Review, 2020)

Pleiotropic regulation of daptomycin synthesis by DptR1, a LuxR family transcriptional regulator - Guanghai Yu; Ming Hui; Ruifang Li; Shuaibing Zhang (World Journal of Microbiology and Biotechnology, 2020)

WDR5a functions in cadmium-inhibited root meristem growth by regulating nitric oxide accumulation in Arabidopsis - Yu Zhang; Yang-Yang Tian; Lin-Feng Wang; Yun-Hui Li; Ting-Ting Li; Wen-Cheng Liu (Planta, 2020)

Spinal CCL2 Promotes Pain Sensitization by Rapid Enhancement of NMDA-Induced Currents Through the ERK-GluN2B Pathway in Mouse Lamina II Neurons - Hui Zhang; Sui-Bin Ma; Yong-Jing Gao; Jun-Ling Xing; Hang Xian; Zhen-Zhen Li; Shu-Ning Shen; Sheng-Xi Wu; Ceng Luo; Rou-Gang Xie (Neuroscience Bulletin, 2020)
Previous studies have shown that CCL2 (C–C motif chemokine ligand 2) induces chronic pain, but the exact mechanisms are still unknown. Here, we established models to explore the potential mechanisms. Behavioral experiments revealed that an antagonist of extracellular signal-regulated kinase (ERK) inhibited not only CCL2-induced inflammatory pain, but also pain responses induced by complete Freund’s adjuvant. We posed the question of the intracellular signaling cascade involved. Subsequent experiments showed that CCL2 up-regulated the expression of phosphorylated ERK (pERK) and N-methyl D-aspartate receptor [NMDAR] subtype 2B (GluN2B); meanwhile, antagonists of CCR2 and ERK effectively reversed these phenomena. Whole-cell patch-clamp recordings revealed that CCL2 enhanced the NMDAR-induced currents via activating the pERK pathway, which was blocked by antagonists of GluN2B and ERK. In summary, we demonstrate that CCL2 directly interacts with CCR2 to enhance NMDAR-induced currents, eventually leading to inflammatory pain mainly through the CCL2–CCR2–pERK–GluN2B pathway.

Fasudil attenuates glial cell-mediated neuroinflammation via ERK1/2 and AKT signaling pathways after optic nerve crush - Wei Huang; Qianqian Lan; Li Jiang; Wenya Yan; Fen Tang; Chaolan Shen; Hui Huang; Haibin Zhong; Jian Lv; Siming Zeng; Min Li; Zhongxiang Mo; et al. (Molecular Biology Reports, 2020)

Astragaloside protects rat brain from microwave-induced functional injuries via restoring acetylcholine and normalizing electroencephalogram - Li Zhao; Yunbo Sun; Chao Yu; Junjun Chen; Xinping Xu; Xueyan Zhang; Hui Wang; Jing Zhang; Haoyu Wang; Ji Dong; Binwei Yao; Hongmei Zhou; et al. (Environmental Science and Pollution Research, 2020)

Predicting the spatiotemporal characteristics of flash droughts with downscaled CMIP5 models in the Jinghe River basin of China - Hui Ran; Jing Li; Zixiang Zhou; Cheng Zhang; Chengyan Tang; Yuyang Yu (Environmental Science and Pollution Research, 2020)

The Composition of Gut Microbiota Community Structure of Jankowski’s Bunting (Emberiza jankowskii) - Weiping Shang; Shi Li; Lishi Zhang; Hui Wu; Yunlei Jiang (Current Microbiology, 2020)

Enhancement of protoplast preparation and regeneration of Hirsutella sinensis based on process optimization - Li-Qun Jin; Zhe-Wen Xu; Xiao-Hui Men; Bo-Zhang; Zhi-Qiang Liu; Yu-Guo Zheng (Biotechnology Letters, 2020)

A long glacier mass balance record analysis in Chinese Urumqi Glacier No. 1 and the relationships with changes in large-scale circulations - Huai Baojuan; Sun Weijun; Wang Junyao; Wang Yetang; Li Zhongqin; Zhang Hui (Arabian Journal of Geosciences, 2020)

Variation in dustfall on the western Chinese Loess Plateau - Xunming Wang; Diwen Cai; Junpeng Lou; Zhenghua Tao; Hui Li; Caixia Zhang (Arabian Journal of Geosciences, 2020)

Sulfur isotopic compositions of sulfides along the Southwest Indian Ridge: implications for mineralization in ultramafic rocks - Teng Ding; Chunhui Tao; Ágata Alveirinho Dias; Jin Liang; Jie Chen; Bin Wu; Dongsheng Ma; Rongqing Zhang; Jia Wang; Shili Liao; Yuan Wang; Weifang Yang; et al. (Mineralium Deposita, 2020)

A pair of new diastereoisomeric phenylpropanoid-substituted flavan from the leaves of Ilex centrochinensis - Hui Long; Yu Chen; Ze-Hua Hu; Shao-Jun Zhang; Lu-Jun Li (Natural Product Research, 2020)

Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis - Ning Xiao; Tian-long Liu; Hao Li; Hao-chen Xu; Jing Ge; Hong-yan Wen; Cong-xia Bai; Li Song; Ying-ying Sun; Yin-hui Zhang; Ru-tai Hui; Wei-hua Song; et al. (Translational Stroke Research, 2020)

PSD-93 Interacts with SynGAP and Promotes SynGAP Ubiquitination and Ischemic Brain Injury in Mice - Qingxiu Zhang; Hui Yang; Hong Gao; Xiaomei Liu; Qingjie Li; Rong Rong; Zhenqian Liu; Xiu-e Wei; Liping Kong; Yun Xu; Liangqun Rong (Translational Stroke Research, 2020)

Genomic prediction across years in a maize doubled haploid breeding program to accelerate early-stage testcross testing - Nan Wang; Hui Wang; Ao Zhang; Yubo Liu; Diansi Yu; Zhuanfang Hao; Dan Ilut; Jeffrey C. Glaubitz; Yanxin Gao; Elizabeth Jones; Michael Olsen; Xinhai Li; et al. (Theoretical and Applied Genetics, 2020)
Key message Genomic selection with a multiple-year training population dataset could accelerate early-stage testcross testing by skipping the first-stage yield testing, which significantly saves the time and cost of early-stage testcross testing. Abstract With the development of doubled haploid (DH) technology, the main task for a maize breeder is to estimate the breeding values of thousands of DH lines annually. In early-stage testcross testing, genomic selection (GS) offers the opportunity of replacing expensive multiple-environment phenotyping and phenotypic selection with lower-cost genotyping and genomic estimated breeding value (GEBV)-based selection. In the present study, a total of 1528 maize DH lines, phenotyped in multiple-environment trials in three consecutive years and genotyped with a low-cost per-sample genotyping platform of rAmpSeq, were used to explore how to implement GS to accelerate early-stage testcross testing. Results showed that the average prediction accuracy estimated from the cross-validation schemes was above 0.60 across all the scenarios. The average prediction accuracies estimated from the independent validation schemes ranged from 0.23 to 0.32 across all the scenarios, when the one-year datasets were used as training population (TRN) to predict the other year data as testing population (TST). The average prediction accuracies increased to a range from 0.31 to 0.42 across all the scenarios, when the two-years datasets were used as TRN. The prediction accuracies increased to a range from 0.50 to 0.56, when the TRN consisted of two-years of breeding data and 50% of third year’s data converted from TST to TRN. This information showed that GS with a multiple-year TRN set offers the opportunity to accelerate early-stage testcross testing by skipping the first-stage yield testing, which significantly saves the time and cost of early-stage testcross testing.

Major genomic regions responsible for wheat yield and its components as revealed by meta-QTL and genotype–phenotype association analyses - Hui Liu; Daniel Mullan; Chi Zhang; Shancen Zhao; Xin Li; Aimin Zhang; Zhanyuan Lu; Yong Wang; Guijun Yan (Planta, 2020)

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway - Jia-Ru Wang; Tian-Zhu Li; Cheng Wang; Shu-Mei Li; Ying-Hua Luo; Xian-Ji Piao; Yu-Chao Feng; Yi Zhang; Wan-Ting Xu; Yu Zhang; Tong Zhang; Shi-Nong Wang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Erythropoietin-Induced Autophagy Protects Against Spinal Cord Injury and Improves Neurological Function via the Extracellular-Regulated Protein Kinase Signaling Pathway - Lin Zhong; Hui Zhang; Zheng-Fei Ding; Jian Li; Jin-Wei Lv; Zheng-Jun Pan; De-Xiang Xu; Zong-Sheng Yin (Molecular Neurobiology, 2020)

A LiDAR aiding ambiguity resolution method using fuzzy one-to-many feature matching - Chuang Qian; Hongjuan Zhang; Wenzhuo Li; Bao Shu; Jian Tang; Bijun Li; Zhijun Chen; Hui Liu (Journal of Geodesy, 2020)

Increased O-GlcNAcylation induces myocardial hypertrophy - Xiaoli Chen; Li Zhang; Hui He; Yikai Sun; Qin Shen; Linsheng Shi (In Vitro Cellular & Developmental Biology - Animal, 2020)