Co-Delivery Using pH-Sensitive Liposomes to Pancreatic Cancer Cells: the Effects of Curcumin on Cellular Concentration and Pharmacokinetics of Gemcitabine - Hongtao Xu; Yan Li; James W. Paxton; Zimei Wu (Pharmaceutical Research, 2021)

Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons - Xiaolei Song; Haotian Chen; Zicong Shang; Heng Du; Zhenmeiyu Li; Yan Wen; Guoping Liu; Dashi Qi; Yan You; Zhengang Yang; Zhuangzhi Zhang; Zhejun Xu (Neuroscience Bulletin, 2021)
Medium spiny neurons (MSNs) in the striatum, which can be divided into D1 and D2 MSNs, originate from the lateral ganglionic eminence (LGE). Previously, we reported that Six3 is a downstream target of Sp8/Sp9 in the transcriptional regulatory cascade of D2 MSN development and that conditionally knocking out Six3 leads to a severe loss of D2 MSNs. Here, we showed that Six3 mainly functions in D2 MSN precursor cells and gradually loses its function as D2 MSNs mature. Conditional deletion of Six3 had little effect on cell proliferation but blocked the differentiation of D2 MSN precursor cells. In addition, conditional overexpression of Six3 promoted the differentiation of precursor cells in the LGE. We measured an increase of apoptosis in the postnatal striatum of conditional Six3 -knockout mice. This suggests that, in the absence of Six3, abnormally differentiated D2 MSNs are eliminated by programmed cell death. These results further identify Six3 as an important regulatory element during D2 MSN differentiation.

The influence of VDR polymorphisms on the type 2 diabetes susceptibility in Chinese: an interaction with hypertriglyceridemia - Dongdong Zhang; Cheng Cheng; Yan Wang; Yuan Xue; Yaping Liu; Yiming Liu; Mingming Feng; Ze Xu; Wenjie Li; Xing Li (Molecular Genetics and Genomics, 2021)

Phytochelatins formation kinetics and Cd-induced growth inhibition in Lolium perenne L. at elevated CO2 level under Cd stress - Ying Shi; Yaqi Liu; Houyu Li; Haopeng Pei; Yan Xu; Xuehai Ju (Environmental Science and Pollution Research, 2021)

Preferential capture of phosphate by an Enteromorpha prolifera–based biopolymer encapsulating hydrous zirconium oxide nanoparticles - Qian-Qian Zhong; Li Shen; Ya-Qin Zhao; Yu-Cui Hao; Li-Cong Meng; Yan-Juan Liu; Xing Xu; Ya-Nan Shang; Bao-Yu Gao; Qin-Yan Yue (Environmental Science and Pollution Research, 2021)

Serum Iron and Ferritin Levels Are Correlated with Complement C3 - Shuang Wen; Yeqin Sha; Yinling Li; Zhilian Rui; Chenhong Si; Yuning Zhou; Fengfeng Yan; Bicheng Wang; Jingming Hu; Xu Han; Dongyan Shi (Biological Trace Element Research, 2021)

Brevibacterium renqingii sp. nov., isolated from the Daqu of Baijiu - Yi Yan; Xuan Xing; Zhanbin Sun; Jia Li; Shuyue Hao; Jialiang Xu (Archives of Microbiology, 2021)

Structural identification of fault zones based on wavelet attributes of logging data - Xingyu Xu; Dongdong Yan; Jingjing Qi; Jianing Li; Jianmeng Sun; Xiaoyu Liu; Tao Xu (Arabian Journal of Geosciences, 2021)

Ziziphus jujuba Mill., a plant used as medicinal food: a review of its phytochemistry, pharmacology, quality control and future research - Shi-Jun Liu; Yan-Ping Lv; Zhi-Shu Tang; Yu Zhang; Hong-Bo Xu; Dong-Bo Zhang; Chun-Li Cui; Hong-Bo Liu; Huan-Huan Sun; Zhong-Xing Song; Si-Min Wei (Phytochemistry Reviews, 2021)

RNA-Seq Transcriptome Analysis of the Liver and Brain of the Black Carp (Mylopharyngodon piceus) During Fasting - Ya-Fan Dai; Yu-bang Shen; Shen-Tong Wang; Jia-Hua Zhang; Yu-Hong Su; Sheng-Chen Bao; Xiao-Yan Xu; Jia-Le Li (Marine Biotechnology, 2021)

Serum macrophage migration inhibitory factor as a potential biomarker to evaluate therapeutic response in patients with allergic asthma: an exploratory study - Huiyuan Zhu; Shaochun Yan; Jingshuo Wu; Zhong Zhang; Xiaolin Li; Zheng Liu; Xing Ma; Lina Zhou; Lin Zhang; Mingming Feng; Yiwei Geng; Aixin Zhang; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Analysis of variation patterns in rice milled quality in the offspring of indica–japonica hybridization - Ting Mao; Zhan Zhang; Shan-Jun Ni; Yi-Zhou Zhao; Xin Li; Li-Li Zhang; Yan Liu; Xu Li (Genetic Resources and Crop Evolution, 2021)

Enhanced treatment of shale gas fracturing waste fluid through plant-microbial synergism - Bo Shao; Xu Tan; Ju-Long Li; Mei He; Lei Tian; Wen-Jie Chen; Yan Lin (Environmental Science and Pollution Research, 2021)

Effects of multi-phase inoculation on the fungal community related with the improvement of medicinal herbal residues composting - Xiao-Lin Lu; Hao Wu; Shi-Li Song; Hong-Yan Bai; Meng-Jun Tang; Fang-Ji Xu; Yan Ma; Chuan-Chao Dai; Yong Jia (Environmental Science and Pollution Research, 2021)

Association between fine particulate matter and heart failure hospitalizations: a time-series analysis in Yancheng, China - Xu Li; Hongyi Cheng; Yan Fang; Zhichao Chen; Guangyu Qi; Renjie Chen; Haidong Kan; Cong Liu; Jingyan Cao (Environmental Science and Pollution Research, 2021)

Environmental impact of express food delivery in China: the role of personal consumption choice - Jingyi Xie; Yan Xu; Haixiao Li (Environment, Development and Sustainability, 2021)

Alterinioella nitratireducens gen. nov., sp. nov., Isolated from Seawater in the West Pacific Ocean - Yan-Hui Kong; Cong Sun; Li-Li Guo; Lin Xu; Yue-Hong Wu; Xue-Wei Xu (Current Microbiology, 2021)

Generation and identification of endothelial-specific Hrh2 knockout mice - Rui Meng; Wen-Ke Cai; Wen-Mang Xu; Qiang Feng; Ping Wang; Yan-hua Huang; Yu-Xin Fan; Tao Zhou; Qin Yang; Zhi-Ran Li; Gong-Hao He (Transgenic Research, 2021)

Study on strength characteristics and mechanism of loess stabilized by F1 ionic soil stabilizer - Jian-dong Li; Xu Wang; Yan-jie Zhang; Dai-jun Jiang; De-ren Liu; Jing-long Wang (Arabian Journal of Geosciences, 2021)

Design of supercontinuum laser hyperspectral light detection and ranging (LiDAR) (SCLaHS LiDAR) - Guoqing Zhou; Xiang Zhou; Youjian Song; Donghui Xie; Long Wang; Guangjian Yan; Minglie Hu; Bowen Liu; Weidong Shang; Chenghu Gong; Cheng Wang; Huaguo Huang; et al. (International Journal of Remote Sensing, 2021)

Geological settings and metallogenesis of high-grade iron deposits in China - Zhaochong Zhang; Houmin Li; Jianwei Li; Xie-Yan Song; Hao Hu; Lixing Li; Fengmei Chai; Tong Hou; Deru Xu (Science China Earth Sciences, 2021)

Apatinib regulates the growth of gastric cancer cells by modulating apoptosis and autophagy - Xu Liu; Qiaoyu Zheng; Qiongfang Yu; Yan Hu; Yanmin Cheng; Zhaozhao Shao; Li Chen; Wenjie Ding; Dian Gao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Study on characteristics of waterflooding in fractured reservoirs based on discrete fracture model - Fanle Meng; Junjian Li; Hanqiao Jiang; Lin Zhao; Linkai Li; Yan Qiao; Yu Zhou; Fei Xu (Arabian Journal of Geosciences, 2021)

3-Hz Postural Tremor in MSA-C and SCA: Revisiting an Old but Underestimated Cerebellar Sign by Posturography - Xiaodi Li; Xiao Lv; Churong Liu; Jinlong Ye; Yan Xu; Gengmao Ma; Zhong Li; Yuzhou Wang (The Cerebellum, 2021)

Evaluation of the efficacy and safety of hydroxychloroquine in comparison with chloroquine in moderate and severe patients with COVID-19 - Qiuyu Li; Cheng Cui; Fei Xu; Jianping Zhao; Nan Li; Haichao Li; Tianbing Wang; Hua Zhang; Na Liu; Yudong Wei; Xiaoye Niu; Yan Xu; et al. (Science China Life Sciences, 2021)

OsNAC109 regulates senescence, growth and development by altering the expression of senescence- and phytohormone-associated genes in rice - Liangjian Li; Yan He; Zhihong Zhang; Yongfeng Shi; Xiaobo Zhang; Xia Xu; Jian-li Wu; Shaoqing Tang (Plant Molecular Biology, 2021)
Key message We demonstrate that OsNAC109 regulates senescence, growth and development via binding to the cis-element CNTCSSNNSCAVG and altering the expression of multiple senescence- and hormone-associated genes in rice. Abstract The NAC family is one of the largest transcripton factor families in plants and plays an essential role in plant development, leaf senescence and responses to biotic/abiotic stresses through modulating the expression of numerous genes. Here, we isolated and characterized a novel yellow leaf 3 ( yl3 ) mutant exhibiting arrested-growth, increased accumulation of reactive oxygen species (ROS), decreased level of soluble proteins, increased level of malondialdehyde (MDA), reduced activities of ROS scavenging enzymes, altered expression of photosynthesis and senescence/hormone-associated genes. The yellow leaf and arrested-growth trait was controlled by a single recessive gene located to chromosome 9. A single nucleotide substitution was detected in the mutant allele leading to premature termination of its coding protein. Genetic complementation could rescue the mutant phenotype while the YL3 knockout lines displayed similar phenotype to WT. YL3 was expressed in all tissues tested and predicted to encode a transcriptional factor OsNAC109 which localizes to the nucleus. It was confirmed that OsNAC109 could directly regulate the expression of OsNAP , OsNYC3 , OsEATB , OsAMTR1 , OsZFP185 , OsMPS and OsGA2ox3 by targeting to the highly conserved cis-element CNTCSSNNSCAVG except OsSAMS1 . Our results demonstrated that OsNAC109 is essential to rice leaf senescence, growth and development through regulating the expression of senescence- and phytohormone-associated genes in rice.

A Photopolymerized Semi-Interpenetrating Polymer Networks-Based Hydrogel Incorporated with Nanoparticle for Local Chemotherapy of Tumors - Yeying Wang; Qilong Li; Jing-e Zhou; Jingwen Tan; Minghao Li; Nan Xu; Feng Qu; Jian Chen; Ji Li; Jing Wang; Zhiqiang Liang; Lei Yu; et al. (Pharmaceutical Research, 2021)

Decoding Cortical Glial Cell Development - Xiaosu Li; Guoping Liu; Lin Yang; Zhenmeiyu Li; Zhuangzhi Zhang; Zhejun Xu; Yuqun Cai; Heng Du; Zihao Su; Ziwu Wang; Yangyang Duan; Haotian Chen; et al. (Neuroscience Bulletin, 2021)
Mouse cortical radial glial cells (RGCs) are primary neural stem cells that give rise to cortical oligodendrocytes, astrocytes, and olfactory bulb (OB) GABAergic interneurons in late embryogenesis. There are fundamental gaps in understanding how these diverse cell subtypes are generated. Here, by combining single-cell RNA-Seq with intersectional lineage analyses, we show that beginning at around E16.5, neocortical RGCs start to generate ASCL1 + EGFR + apical multipotent intermediate progenitors (MIPCs), which then differentiate into basal MIPCs that express ASCL1, EGFR, OLIG2, and MKI67. These basal MIPCs undergo several rounds of divisions to generate most of the cortical oligodendrocytes and astrocytes and a subpopulation of OB interneurons. Finally, single-cell ATAC-Seq supported our model for the genetic logic underlying the specification and differentiation of cortical glial cells and OB interneurons. Taken together, this work reveals the process of cortical radial glial cell lineage progression and the developmental origins of cortical astrocytes and oligodendrocytes.

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

Physical Simulations of Gas Production Mechanism in Constant-Rate Co-production from Multiple Coal Reservoirs - Qixian Li; Jiang Xu; Shoujian Peng; Fazhi Yan; Bin Zhou; Ende Han; Cheng Jiang (Natural Resources Research, 2021)

A novel homozygous nonsense mutation in the CA2 gene (c.368G>A, p.W123X) linked to carbonic anhydrase II deficiency syndrome in a Chinese family - Yan Yang; Nie Tang; Ying Zhu; Lei Zhang; Xu Cao; Limei Liu; Wei Xia; Pengqiu Li; Yi Yang (Metabolic Brain Disease, 2021)

miR-495 reduces neuronal cell apoptosis and relieves acute spinal cord injury through inhibiting PRDM5 - Yan Zhang; Shanshan Wang; Hongli Li; Xia Xu (Journal of Molecular Histology, 2021)

Clinical and microbiological characteristics of adults with hospital-acquired pneumonia: a 10-year prospective observational study in China - Yuyao Yin; Chunjiang Zhao; Henan Li; Longyang Jin; Qi Wang; Ruobing Wang; Yawei Zhang; Jiangang Zhang; Hui Wang; Chunxia Yang; Bin Cao; Yingmei Liu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Epimutational effects of electronic cigarettes - Rui Yan; Xu-Li Chen; Yan-Ming Xu; Andy T. Y. Lau (Environmental Science and Pollution Research, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

A novel Schiff base cobalt(III) complex induces a synergistic effect on cervical cancer cells by arresting early apoptosis stage - Wen-Hui Liao; Xue-Qing Song; Yan-Jie Kong; Rui-Dan Bao; Fang-Fang Li; Jie Zhou; Qi-Hua Zhao; Jing-Yuan Xu; Ni Xie; Ming-Jin Xie (BioMetals, 2021)

Initial ingestion of CMV-infected plants reduces subsequent aphid performance - Xiao-bin Shi; Jun Deng; Zhuo Zhang; Shuo Yan; Li-min Zheng; Shu-e Sun; Yang Gao; Xu-guo Zhou; De-yong Zhang; Yong Liu (Arthropod-Plant Interactions, 2021)

Formation and driving factors of sulfate in PM2.5 at a high-level atmospheric SO2 city of Yangquan in China - Cheng Wang; Yulong Yan; Yueyuan Niu; Rumei Li; Yang Xu; Dongmei Hu; Jing Wu; Lin Peng (Air Quality, Atmosphere & Health, 2021)

Global patterns in leaf stoichiometry across coastal wetlands - Yu‐Kun Hu; Xu‐Yan Liu; Nian‐Peng He; Xu Pan; Song‐Yuan Long; Wei Li; Man‐Yin Zhang; Li‐Juan Cui (Global Ecology and Biogeography, 2021)
Aim Coastal wetlands provide crucial ecosystem functions and services, such as coastal protection, nutrient retention and C sequestration. Despite the important roles in global C, N and P cycling, the global variation in leaf stoichiometry across coastal wetlands remains unclear. Location Global. Time period 1980–2018. Major taxa studied Vascular plants. Methods By compiling a global dataset of 698 data records in 205 sites, we carried out systematic analyses of the world‐wide trends and their determinants of leaf element contents and ratios of plants across coastal wetlands. Results Leaf N and P contents increased significantly, but C:N, C:P and N:P ratios decreased with increasing latitude in coastal wetlands. The mean annual temperature was the predominant driver of leaf N, P and C:N, whereas soil N:P was a good predictor of leaf C:P and N:P ratios. Furthermore, N increased faster with P in plant leaves of coastal wetlands compared with terrestrial ecosystems. Within coastal wetlands, herb‐dominated salt marshes had a significantly higher leaf P content, lower leaf N:P ratio and lower scaling exponent of leaf N to P than tree‐dominated mangroves. Main conclusions The similar latitudinal patterns of leaf stoichiometry in coastal wetlands compared with terrestrial ecosystems reflected the similar influences of temperature. However, different slopes of leaf P and N:P ratios and N and P scaling relationships between these two ecosystems suggested that different salinity and tidal inundation levels result in different strategies of N and P use in coastal wetland plants. These differences in leaf stoichiometry between ecosystems and between different types of coastal wetlands might need to be emphasized in future biogeochemical modelling owing to their different roles in global nutrient and carbon cycling.

EmhR is an indole‐sensing transcriptional regulator responsible for the indole‐induced antibiotic tolerance in Pseudomonas fluorescens - Jian‐Ting Han; Di‐Yin Li; Meng‐Yuan Zhang; Xiao‐Quan Yu; Xiang‐Xue Jia; Hang Xu; Xu Yan; Wen‐Juan Jia; Shaomin Niu; Megan L. Kempher; Xuanyu Tao; Yong‐Xing He (Environmental Microbiology, 2021)
Summary Indole is well known as an interspecies signalling molecule to modulate bacterial physiology; however, it is not clear how the indole signal is perceived and responded to by plant growth promoting rhizobacteria (PGPR) in the rhizosphere. Here, we demonstrated that indole enhanced the antibiotic tolerance of Pseudomonas fluorescens 2P24, a PGPR well known for its biocontrol capacity. Proteomic analysis revealed that indole influenced the expression of multiple genes including the emhABC operon encoding a major multidrug efflux pump. The expression of emhABC was regulated by a TetR‐family transcription factor EmhR, which was demonstrated to be an indole‐responsive regulator. Molecular dynamics simulation showed that indole allosterically affected the distance between the two DNA‐recognizing helices within the EmhR dimer, leading to diminished EmhR–DNA interaction. It was further revealed the EmhR ortholog in Pseudomonas syringae was also responsible for indole‐induced antibiotic tolerance, suggesting this EmhR‐dependent, indole‐induced antibiotic tolerance is likely to be conserved among Pseudomonas species. Taken together, our results elucidated the molecular mechanism of indole‐induced antibiotic tolerance in Pseudomonas species and had important implications on how rhizobacteria sense and respond to indole in the rhizosphere.

Mutation in ε-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice - Jiao Li; Yiqiong Liu; Qin Li; Xiaolin Huang; Dingxi Zhou; Hanjian Xu; Feng Zhao; Xiaoxiao Mi; Ruoxu Wang; Fan Jia; Fuqiang Xu; Jing Yang; et al. (Neuroscience Bulletin, 2021)

Retraction Note to: Resibufogenin suppresses tumor growth and inhibits glycolysis in ovarian cancer by modulating PIM1 - Qian Li; Chuanwu Jiang; Yan Wang; Minghua Wei; Huijin Zheng; Yanqi Xu; Xuegang Xu; Fengyu Jia; Kai Liu; Gang Sun; Jianhua Zang; Ping Mo (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Validation of suitable reference genes for qRT-PCR in cabbage (Brassica oleracea L.) under different abiotic stress experimental conditions - Aisong Zeng; Yuanyuan Xu; Lixiao Song; Jiaqing Li; Jiyong Yan (Journal of Plant Biochemistry and Biotechnology, 2021)

Chemical polymorphism regulates the attractiveness to nymphs in the bean bug Riptortus pedestris - Hao Xu; Jiajia Zhao; Faqian Li; Qi Yan; Ling Meng; Baoping Li (Journal of Pest Science, 2021)

Evaluation of subsurface, mulched and non-mulched surface drip irrigation for maize production and economic benefits in northeast China - Dan Wang; Guangyong Li; Yan Mo; Ding Zhang; Xinhan Xu; Carol Jo Wilkerson; Gerrit Hoogenboom (Irrigation Science, 2021)

PCDD/Fs characteristics in flue gas and surrounding environment of iron and steel smelting industry - Mingxiu Zhan; Yufeng Ma; Tong Chen; Xiaoqing Lin; Shiying Zhang; Shuaixi Xu; Xiaodong Li; Jianhua Yan (Environmental Science and Pollution Research, 2021)

CO2 dynamic of Lake Donghu highlights the need for long-term monitoring - Xingcheng Yan; Jie Ma; Zhichun Li; Ming Ji; Jie Xu; Xiaoguang Xu; Guoxiang Wang; Yunmei Li (Environmental Science and Pollution Research, 2021)

Examining construction waste management policies in mainland China for potential performance improvements - Hao Lv; Yashuai Li; Hong-Bin Yan; Di Wu; Guanqun Shi; Qian Xu (Clean Technologies and Environmental Policy, 2021)

Soil amendment in plastic greenhouse using modified biochar: soil bacterial diversity responses and microbial biomass carbon and nitrogen - Bin Hua; Zhouwen Li; Weikai Gao; Huilin Feng; Nan Chen; Jiayi Li; Xiaoming Ji; Lu Zhang; Zhiyong Wu; Shen Yan; Tianbao Ren; Chensheng Xu; et al. (Biotechnology Letters, 2021)

Small RNA Sequencing Analysis of Germinating Single-bud Seedcane Sett in Sugarcane - Kai-Chao Wu; Lin Xu; Zhi-Nian Deng; Tian Pang; Rong-Hua Zhang; Yi-Jie Li; Xiao-Yan Liu; Cheng-Feng Huang; Wen-Xian Qin; Jian-Feng Wei; Li-Ping Wei; Yang-Rui Li; et al. (Sugar Tech, 2021)

Down-regulation of MANNANASE7 gene in Brassica napus L. enhances silique dehiscence-resistance - Yu-Long Li; Yan-Kun Yu; Ke-Ming Zhu; Li-Na Ding; Zheng Wang; Yan-Hua Yang; Jun Cao; Li-Zhang Xu; Yao-Ming Li; Xiao-Li Tan (Plant Cell Reports, 2021)

Interleukin-38 overexpression prevents bleomycin-induced mouse pulmonary fibrosis - Zhiwei Xu; Xianli Yuan; Qiaoyan Gao; Yan Li; Mingcai Li (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Identification and expression of the BAHD family during development, ripening, and stress response in banana - Yun Xu; Weiwei Tie; Yan Yan; Biyu Xu; Juhua Liu; Meiying Li; Jinghao Yang; Jian Zeng; Wei Hu; Zhiqiang Jin (Molecular Biology Reports, 2021)

Assisted selection of eating quality progeny of indica (O. sativa L. ssp. indica) and japonica (O. sativa L. ssp. japonica) hybrids using rice starch properties - Ting Mao; Zhan Zhang; Shan Jun Ni; Yi Zhou Zhao; Xin Li; Li Li Zhang; Yan Liu; Cheng Shun Zhong; He Huang; Shao Lin Wang; Xu Li (Genetic Resources and Crop Evolution, 2021)

Starch bio-template synthesis of W-doped CeO2 catalyst for selective catalytic reduction of NOx with NH3: influence of ignition temperature - Zhi-Bo Xiong; Zhen-Zhuang Li; Yan-Ping Du; Cheng-Xu Li; Wei Lu; Su-Le Tian (Environmental Science and Pollution Research, 2021)

Association between selected urinary heavy metals and asthma in adults: a retrospective cross-sectional study of the US National Health and Nutrition Examination Survey - Xiuzhu Li; Yun Fan; Yan Zhang; Xiaomin Huang; Zhenyao Huang; Mingming Yu; Qiaoqiao Xu; Xiumei Han; Chuncheng Lu; Xinru Wang (Environmental Science and Pollution Research, 2021)

Effects of rotational and continuous overgrazing on newly assimilated C allocation - Min Liu; Shengnan Ouyang; Yuqiang Tian; Shuhai Wen; Yan Zhao; Xiaobing Li; Taoge-tao Baoyin; Yakov Kuzyakov; Xingliang Xu (Biology and Fertility of Soils, 2021)

An Intra-Oceanic Subduction System Influenced by Ridge Subduction in the Diyanmiao Subduction Accretionary Complex of the Xar Moron Area, Eastern Margin of the Central Asian Orogenic Belt - Yang Cheng; Qinghui Xiao; Tingdong Li; Liquan Xu; Yuxu Fan; Yan Li; Lingjun Guo; Jinli Pang; Weiming Yuan (Journal of Earth Science, 2021)

Dominant factor of dry‐wet change in China since 1960s - Jinqin Xu; Dandan Wang; Xinfa Qiu; Yan Zeng; Xiaochen Zhu; Mengxi Li; Yongjian He; Guoping Shi (International Journal of Climatology, 2021)
The dry‐wet climate conditions of an area are mainly determined by the water input (e.g., precipitation, P) and output (e.g., potential evapotranspiration, PET). Based on three dry‐wet indices and the differential equation, this study designed a new attribution method to quantify the contributions of P and PET to the dry‐wet change, so as to determine the dominant factors of the dry‐wet change over whole China (CHINA) and various hydroclimate regions (i.e., arid region, AR; semi‐arid region, SAR; semi‐humid region, SHR; and humid region, HR) during 1960–2018 and six interdecadal periods. Results showed that the overall weak drying in CHINA was dominated by an increase in PET, while climate humidification in AR and HR was dominated by an increase in P, climate drying in SHR was dominated by the reduced P, and the weak drying in SAR was co‐dominated by P and PET during 1960–2018. The dominant factors of dry‐wet change over CHINA and each hydroclimate region varied in different decades. Briefly, climate humidification in CHINA and various hydroclimate regions was basically dominated by P in different decades, and the drying was mainly dominated by P in the 1960s–1980s, but the contribution of PET to climate drying began to become prominent after the 1980s. Besides, we found that P contributed more to dry‐wet change than PET on the station and regional scales, but the contribution of P to climate drying on a national scale was underestimated to some extent due to the regional offset effect of the increase/decrease in P during 1960–2018, as well as in the 1990s. These findings implied that the importance of research on the regional or local scale, and equal attention should be paid to the effects of P and PET changes in the future drought or dry‐wet change research.

Harnessing the type I CRISPR‐Cas systems for genome editing in prokaryotes - Zeling Xu; Yanran Li; Ming Li; Hua Xiang; Aixin Yan (Environmental Microbiology, 2021)
Summary Genetic analysis is crucial to the understanding, exploitation, and control of microorganisms. The advent of CRISPR‐Cas‐based genome‐editing techniques, particularly those mediated by the single‐effector (Cas9 and Cas12a) class 2 CRISPR‐Cas systems, has revolutionized the genetics in model eukaryotic organisms. However, their applications in prokaryotes are rather limited, largely owing to the exceptional diversity of DNA homeostasis in microorganisms and severe cytotoxicity of overexpressing these nuclease proteins in certain genotypes. Remarkably, CRISPR‐Cas systems belonging to different classes and types are continuously identified in prokaryotic genomes and serve as a deep reservoir for expansion of the CRISPR‐based genetic toolkits. ~90% of the CRISPR‐Cas systems identified so far belong to the class 1 system which hinges on multi‐protein effector complexes for DNA interference. Harnessing these widespread native CRISPR‐Cas systems for ‘built‐in’ genome editing represents an emerging and powerful genetic tool in prokaryotes, especially in the genetically recalcitrant non‐model species and strains. In this progress review, we introduce the general workflow of this emerging editing platform and summarize its establishment in a growing number of prokaryotes by harnessing the most widespread, diverse type I CRISPR‐Cas systems present in their genomes. We also discuss the various factors affecting the success and efficiency of this editing platform and the corresponding solutions.

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Construction and characterization of UAA-controlled recombinant Zika virus by genetic code expansion - Rong-Rong Zhang; Qing Ye; Xiao-Feng Li; Yong-Qiang Deng; Yan-Peng Xu; Xing-Yao Huang; Qing Xia; Cheng-Feng Qin (Science China Life Sciences, 2021)

7,8-Dihydroxyflavone Alleviates Anxiety-Like Behavior Induced by Chronic Alcohol Exposure in Mice Involving Tropomyosin-Related Kinase B in the Amygdala - Na Wang; Xing Liu; Xin-Tong Li; Xin-Xin Li; Wei Ma; Yan-Min Xu; Yong Liu; Qing Gao; Tao Yang; Hongxuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2021)

Uric acid drives intestinal barrier dysfunction through TSPO-mediated NLRP3 inflammasome activation - Qiulan Lv; Daxing Xu; Jinfeng Ma; Yan Wang; Xiaomin Yang; Peng Zhao; Liang Ma; Zhiyuan Li; Wan Yang; Xiu Liu; Guanpin Yang; Shichao Xing (Inflammation Research, 2021)

LncRNA TUG1 regulates the balance of HuR and miR-29b-3p and inhibits intestinal epithelial cell apoptosis in a mouse model of ulcerative colitis - Yuxi Tian; Ying Wang; Fujun Li; Junwen Yang; Yan Xu; Miao Ouyang (Human Cell, 2021)

Adsorption mechanism of rhein-coated Fe3O4 as magnetic adsorbent based on low-field NMR - Xu Sun; Li Xu; Weina Jiang; Yan Xuan; Wen Lu; Zhong Li; Shilong Yang; Zhenzhen Gu (Environmental Science and Pollution Research, 2021)

Effects of Litter Quality Diminish and Effects of Vegetation Type Develop During Litter Decomposition of Two Shrub Species in an Alpine Treeline Ecotone - Haifeng Zheng; Yamei Chen; Yang Liu; Petr Heděnec; Yan Peng; Zhenfeng Xu; Bo Tan; Li Zhang; Li Guo; Lifeng Wang; Lars Vesterdal (Ecosystems, 2021)

Enteromorpha prolifera Diet Drives Intestinal Microbiome Composition in Siganus oramin - Yan Xu; Jin Li; Xuefeng Han; Zhibiao Zhang; Mingqi Zhong; Zhong Hu (Current Microbiology, 2021)

Distance decay of place attachment and perceived authenticity of mountain tourism destinations in China - Xiao Xiao; Jie Zhang; Jun-yu Lu; Li Li; Yan-qing Xu; Hong-lei Zhang; Geoffrey K. Riungu (Journal of Mountain Science, 2021)

Allotransplantation of adult spinal cord tissues after complete transected spinal cord injury: Long-term survival and functional recovery in canines - He Shen; Shuyu Wu; Xi Chen; Bai Xu; Dezun Ma; Yannan Zhao; Yan Zhuang; Bing Chen; Xianglin Hou; Jiayin Li; Yudong Cao; Xianyong Fu; et al. (Science China Life Sciences, 2020)

OsRbohB-mediated ROS production plays a crucial role in drought stress tolerance of rice - Yi Shi; Yan-Li Chang; Hai-Tao Wu; Abdullah Shalmani; Wen-Ting Liu; Wen-Qiang Li; Jian-Wei Xu; Kun-Ming Chen (Plant Cell Reports, 2020)

Iron Aggravates the Depressive Phenotype of Stressed Mice by Compromising the Glymphatic System - Shanshan Liang; Yan Lu; Zexiong Li; Shuai Li; Beina Chen; Manman Zhang; Binjie Chen; Ming Ji; Wenliang Gong; Maosheng Xia; Alexei Verkhratsky; Xu Wu; et al. (Neuroscience Bulletin, 2020)

miR-155-5p alleviates ethanol-induced myocardial insulin resistance in H9C2 cells via regulating the mTOR signalling pathway - Zhaoping Li; Deqiang Shen; Yan Meng; Hongzhao Xu; Huacai Yuan; Liyong Chen (Molecular Biology Reports, 2020)

Factors associated with a SARS-CoV-2 recurrence after hospital discharge among patients with COVID-19: systematic review and meta-analysis - Meng-qi Yao; Qiu-xian Zheng; Jia Xu; Jing-wen Deng; Tian-tian Ge; Hai-bo Zhou; Feng-tian Wu; Xin-yu Gu; Qin Yang; Yan-li Ren; Gang Wang; Zhi Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Effects of Single-Dose and Long-Term Ketamine Administration on Tau Phosphorylation–Related Enzymes GSK-3β, CDK5, PP2A, and PP2B in the Mouse Hippocampus - Yanning Li; Gehua Wen; Runtao Ding; Xinghua Ren; Chenchen Jing; Lin Liu; Jun Yao; Guohua Zhang; Yan Lu; Baoman Li; Xu Wu (Journal of Molecular Neuroscience, 2020)

Valine acts as a nutritional signal in brain to activate TORC1 and attenuate postprandial ammonia-N excretion in Chinese perch (Siniperca chuatsi) - Jie Wang; Xu-Fang Liang; Shan He; Yan-Peng Zhang; Jiao Li; Kang Huang; Lin-Jie Shi; Ping Ren (Fish Physiology and Biochemistry, 2020)

Epidemiological analysis of Group A Streptococcus infections in a hospital in Beijing, China - Hongxin Li; Lin Zhou; Yong Zhao; Lijuan Ma; Jing Xu; Yan Liu; Qin Qin; Jin Hu; Xiaoyan Liu (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Psychological symptoms in Chinese nurses may be associated with predisposition to chronic disease: a cross-sectional study of suboptimal health status - Jinxiu Zhu; Wenjuan Ying; Li Zhang; Gangyi Peng; Weiju Chen; Enoch Odame Anto; Xueqing Wang; Nan Lu; Shanshan Gao; Guihai Wu; Jingyi Yan; Jianfeng Ye; et al. (EPMA Journal, 2020)
Background Suboptimal health status (SHS) is a reversible state between ideal health and illness and it can be effectively reversed by risk prediction, disease prevention, and personalized medicine under the global background of predictive, preventive, and personalized medicine (PPPM) concepts. More and more Chinese nurses have been troubled by psychological symptoms (PS). The correlation between PS and SHS is unclear in nurses. The purpose of current study is to investigate the prevalence of SHS and PS in Chinese nurses and the relationship between SHS and PS along with predisposing factors as well as to discuss the feasibility of improving health status and preventing diseases according to PPPM concepts in Chinese nurses. Methods A cross-sectional study was conducted with the cluster sampling method among 9793 registered nurses in Foshan city, China. SHS was evaluated with the Suboptimal Health Status Questionnaire-25 (SHSQ-25). Meanwhile, the PS of depression and anxiety were evaluated with Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) self-assessment questionnaires. The relationship between PS and SHS in Chinese nurses was subsequently analyzed. Results Among the 9793 participants, 6107 nurses were included in the final analysis. The prevalence of SHS in the participants was 74.21% (4532/6107) while the symptoms of depression and anxiety were 47.62% (2908/6107) and 24.59% (1502/6107) respectively. The prevalence of SHS in the participants with depression and anxiety was significantly higher than those without the symptoms of depression (83.3% vs 16.7%, P < 0.001) and anxiety (94.2% vs 5.8%, P < 0.0001). The ratio of exercise habit was significantly lower than that of non-exercise habit (68.8% vs 78.4%, P < 0.001) in SHS group. Conclusions There is a high prevalence of SHS and PS in Chinese nurses. PS in Chinese nurses are associated with SHS. Physical exercise is a protective factor for SHS and PS so that the exercise should be strongly recommended as a valuable preventive measure well in the agreement with PPPM philosophy. Along with SDS and SAS, SHSQ-25 should also be highly recommended and applied as a novel predictive/preventive tool for the health measures from the perspectives of PPPM in view of susceptible population and individual screening, the predisposition to chronic disease preventing, personalization of intervention, and the ideal health state restoring.

Rho GTPases in cancer radiotherapy and metastasis - Rui-Jie Zeng; Chun-Wen Zheng; Wan-Xian Chen; Li-Yan Xu; En-Min Li (Cancer and Metastasis Reviews, 2020)

Male-biased fasting-induced changes in hepatic tauro-cholic acid and plasma cholesterol in Sult2a8-haplodeficient mice - Kai Wang; Martin Yan-Chun Chan; Jian Xu; Pik-Shan Li; Xing Liu; Angus Yiu-Fai Lee; Susanna Sau-Tuen Lee; Wing-Tai Cheung (Transgenic Research, 2020)

Rapid identification of landslide, collapse and crack based on low-altitude remote sensing image of UAV - Xu-gang Lian; Zou-jun Li; Hong-yan Yuan; Ji-bo Liu; Yan-jun Zhang; Xiao-yu Liu; Yan-ru Wu (Journal of Mountain Science, 2020)

Identification of hybrid green peafowl using mitochondrial and nuclear markers - Han Yu Du; Xin Yuan Zhang; Thi Dao Dinh; Yue Ma; Cheng Zong; Guang Long Li; Thomas D. Dahmer; Yan Chun Xu (Conservation Genetics Resources, 2020)

Application of multi-component joint inversion in oil and gas exploration: A case study of reservoir and gas saturation prediction of the Xujiahe formation in the PLN area of the central Sichuan Basin - Dong Wang; Zhen-Hua He; Xu-Ben Wang; Le Li; Hai-Tao Yang; Zhi-Guo Fu; Hong-Yan Wang (Applied Geophysics, 2020)

Characteristics of discontinuities in Heifangtai landslide area in Gansu, China - Bin Li; Qiang Xu; Qiang Cheng; Tian-Xiang Liu; Ming-Gao Tang; Guang Zheng; Hai-Yan Wang (Applied Geophysics, 2020)

Influence of complex topography on magnetotelluric-observed data using three-dimensional numerical simulation: A case from Guangxi area, China - Xiong Bin; Luo Tian-Ya; Chen Long-Wei; Dai Shi-Kun; Xu Zhi-Feng; Li Chang-Wei; Ding Yan-Li; Wang Hong-Hua; Li Jing-He (Applied Geophysics, 2020)

Role of major histocompatibility complex II antigen‐presentation pathway genes in orange‐spotted grouper infected with Cryptocaryon irritans - Jun‐Jin Deng; Shun Xu; Yan‐Wei Li; Dong‐Dong Xu; Ze‐Quan Mo; Jia‐Zhou Li; Xue‐Ming Dan; Xiao‐Chun Luo (Journal of Fish Diseases, 2020)
Cryptocaryon irritans , a pathogen model for fish mucosal immunity, causes skin mucosal and systematic humoral immune response. Where and how MHC II antigen presentation occurs in fish infected with C . irritans remain unknown. In this study, the full‐length cDNA of the grouper cysteine protease CTSS was cloned. The expression distributions of six genes (CTSB, CTSL, CTSS, GILT, MHC IIA and MHC IIB) involved in MHC II antigen presentation pathway were tested. These genes were highly expressed in systematic immune tissues and skin and gill mucosal‐associated immune tissues. All six genes were upregulated in skin at most time points. Five genes expected CTSS was upregulated in spleen at most time points. CTSB, CTSL and MHC IIA were upregulated in the gill and head kidney at some time points. These results indicate that the presentation of MHC II antigen intensively occurred in local infected skin and gill. Spleen, not head kidney, had the most extensive systematic antigen presentation. In skin, six genes most likely peaked at day 2, earlier than in spleen (5–7 days), marking an earlier skin antibody peak than any recorded in serum previously. This significant and earlier mucosal antigen presentation indicates that specific immune response occurs in local mucosal tissues.

Flavonoids repress the production of antifungal 2, 4‐DAPG but potentially facilitate root colonization of the rhizobacterium Pseudomonas fluorescens - Xiao‐Quan Yu; Xu Yan; Meng‐Yuan Zhang; Li‐Qun Zhang; Yong‐Xing He (Environmental Microbiology, 2020)
Summary In the well‐known legume–rhizobia symbiosis, flavonoids released by legume roots induce expression of the Nod factors and trigger early plant responses involved in root nodulation. However, it remains largely unknown how the plant‐derived flavonoids influence the physiology of non‐symbiotic beneficial rhizobacteria. In this work, we demonstrated that the flavonoids apigenin and/or phloretin enhanced the swarming motility and production of cellulose and curli in Pseudomonas fluorescens 2P24, both traits of which are essential for root colonization. Using a label‐free quantitative proteomics approach, we showed that apigenin and phloretin significantly reduced the biosynthesis of the antifungal metabolite 2,4‐DAPG and further identified a novel flavonoid‐sensing TetR regulator PhlH, which was shown to modulate 2,4‐DAPG production by regulating the expression of 2,4‐DAPG hydrolase PhlG. Although having similar structures, apigenin and phloretin could also influence different physiological characteristics of P . fluorescens 2P24, with apigenin decreasing the biofilm formation and phloretin inducing expression of proteins involved in the denitrification and arginine fermentation processes. Taken together, our results suggest that plant‐derived flavonoids could be sensed by the TetR regulator PhlH in P . fluorescens 2P24 and acts as important signalling molecules that strengthen mutually beneficial interactions between plants and non‐symbiotic beneficial rhizobacteria.

Spororrminone A and 2- epi -spororrminone A, two new chromones from an endolichenic fungus Sporormiella irregularis - Mei-Juan Huang; Yan-Jun Li; Jia Tang; Guo-Dong Chen; Dan Hu; Wei Xu; Liang-Dong Guo; Xin-Sheng Yao; Hao Gao (Natural Product Research, 2020)

Identification and validation of genetic loci for tiller angle in bread wheat - Dehui Zhao; Li Yang; Kaijie Xu; Shuanghe Cao; Yubing Tian; Jun Yan; Zhonghu He; Xianchun Xia; Xiyue Song; Yong Zhang (Theoretical and Applied Genetics, 2020)

Multiple Xanthomonas campestris pv. campestris 8004 type III effectors inhibit immunity induced by flg22 - Yan Huang; Tongqi Li; Ting Xu; Zizhong Tang; Jingya Guo; Yi Cai (Planta, 2020)

Fasudil attenuates glial cell-mediated neuroinflammation via ERK1/2 and AKT signaling pathways after optic nerve crush - Wei Huang; Qianqian Lan; Li Jiang; Wenya Yan; Fen Tang; Chaolan Shen; Hui Huang; Haibin Zhong; Jian Lv; Siming Zeng; Min Li; Zhongxiang Mo; et al. (Molecular Biology Reports, 2020)

The effect of blastomere loss during frozen embryo transfer on the transcriptome of offspring’s umbilical cord blood - Yan-Ting Wu; Ze-Han Dong; Cheng Li; Dai-Zhan Zhou; Jun-Yu Zhang; Yan Wu; Jing-Jing Xu; Yu Wang; Xiao-Qun Ye; Jian-Zhong Sheng; Li Wang; He-Feng Huang (Molecular Biology Reports, 2020)

Population pharmacokinetics and dose optimization of ceftriaxone for children with community-acquired pneumonia - Muhammad Wasim Khan; Ya-Kun Wang; Yue-E Wu; Bo-Hao Tang; Min Kan; Hai-Yan Shi; Yi Zheng; Bao-Ping Xu; A-Dong Shen; Evelyne Jacqz-Aigrain; Li-Yuan Tian; Wei Zhao (European Journal of Clinical Pharmacology, 2020)

Cell plasticity and genomic instability in cancer evolution - Yan Xu; Hui Li; Fan Yang; Dingpeng Yang; Bin-Bing S. Zhou (Genome Instability & Disease, 2020)

Development in sprinkler irrigation technology in China * - Haijun Yan; Xin Hui; Maona Li; Yuncheng Xu (Irrigation and Drainage, 2020)
Since the 1950s, sprinkler irrigation technology in China has gradually realized the localization of key equipment through continuous practice and innovation. A large number of key problems in system design and operation management have been studied and addressed. Remarkable water‐saving and yield increase achievements have been made by sprinkler irrigation in China. At the same time, the continuous improvement of sprinkler irrigation technology has also realized comprehensive benefits in the precision control of water and fertilizer, and has promoted the modernization of China's agriculture and its industrial transformation. In the present paper, the development history of sprinkler irrigation technology in China is reviewed, studies on the basic theory of sprinkler irrigation and the development of sprinkler irrigation equipment are systematically summarized, and research hotspots and new development directions of sprinkler irrigation technology in China are introduced. Finally, prospects and suggestions for the further development of sprinkler irrigation in China are put forward, which provides a basis for the sustainable development of sprinkler irrigation technology. © 2020 John Wiley & Sons, Ltd.

Serological characteristics of COVID-19 patients - Mi Zhou; Jing Zhong; Lei Bi; Pengcheng Shang; Yan Xing; Bo Wang; Jianlan He; Ying Xu; Tao Luo; Maohua Ma; Qingfeng Li (Infectious Diseases, 2020)

New cadinane sesquiterpenoids from Mikania micrantha - Yao Zhang; You-Mei Zeng; You-Kai Xu; Shu-Qi Wu; Shen Li; Hai-Yan Tian; Sheng Yin (Natural Product Research, 2020)

Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis - Ning Xiao; Tian-long Liu; Hao Li; Hao-chen Xu; Jing Ge; Hong-yan Wen; Cong-xia Bai; Li Song; Ying-ying Sun; Yin-hui Zhang; Ru-tai Hui; Wei-hua Song; et al. (Translational Stroke Research, 2020)

Ginsenosides in root exudates of Panax notoginseng drive the change of soil microbiota through carbon source different utilization - Li-Fen Luo; Lei Yang; Zheng-Xu Yan; Bing-Bing Jiang; Su Li; Hui-Chuan Huang; Yi-Xiang Liu; Shu-Sheng Zhu; Min Yang (Plant and Soil, 2020)

Overexpression of the spinach S-nitrosoglutathione reductase (SoGSNOR) in tobacco resulted in enhanced nitrate stress tolerance - Manqi Wang; Yanyan Dong; Jinping Yan; Qinqin Han; Kunzhi Li; Huini Xu (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Do changes in water depth and water level influence the diatom diversity of Yunlong Lake, in Yunnan Province, Southwest China? - Yafei Zou; Luo Wang; Huiming Xu; Yao Yan; Jiaoyang Zhang; Yuan Liu; Peng Li; Zhiyuan Peng; Zhaoyan Gu; Houyuan Lu (Journal of Paleolimnology, 2020)

An accelerated solvent extraction and gas chromatography-flame ionization detector method to rapidly determining and assessing total petroleum hydrocarbon contamination in soil from Fushan oilfield, China - Tengya Li; Xiaocong Cao; Shuhai He; Mingshan Zhang; Wenshuai Xu; Zengheng Xiong; Yan Liang; Chenye Wang; Biaojuan Chen (Environmental Science and Pollution Research, 2020)

Variation in Gut Microbiota of Captive Bengal Slow Lorises - Qingyong Ni; Xin He; Bo Zeng; Xiangyun Meng; Huailiang Xu; Ying Li; Mingyao Yang; Diyan Li; Yongfang Yao; Mingwang Zhang; Yan Li; Xiaolan Fan; et al. (Current Microbiology, 2020)

Puerarin Alleviates Lipopolysaccharide-Induced Myocardial Fibrosis by Inhibiting PARP-1 to Prevent HMGB1-Mediated TLR4-NF-κB Signaling Pathway - Shu-Yuan Ni; Xing-Long Zhong; Ze-Hua Li; Dong-Jian Huang; Wen-Ting Xu; Yan Zhou; Cai-Wen Ou; Min-Sheng Chen (Cardiovascular Toxicology, 2020)

Erratum to: Herbal decoctosome is a novel form of medicine - Xiaoyun Li; Zhu Liang; Jianchao Du; Zhiqing Wang; Song Mei; Zhiqing Li; Yan Zhao; Dandan Zhao; Yiming Ma; Jun Ye; Jiantao Xu; Yu Zhao; et al. (Science China Life Sciences, 2020)

Prevalence of Autism Spectrum Disorder in China: A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years - Hao Zhou; Xiu Xu; Weili Yan; Xiaobing Zou; Lijie Wu; Xuerong Luo; Tingyu Li; Yi Huang; Hongyan Guan; Xiang Chen; Meng Mao; Kun Xia; et al. (Neuroscience Bulletin, 2020)

What factors influence PM2.5 emissions in China? An analysis of regional differences using a combined method of data envelopment analysis and logarithmic mean Divisia index - Shi-Chun Xu; Yi-Feng Zhou; Chao Feng; Yan Wang; Yun-Fan Li (Environmental Science and Pollution Research, 2020)

Addition of oyster shell to enhance organic matter degradation and nitrogen conservation during anaerobic digestate composting - Ming-Yi Lu; Xiao-Shuang Shi; Xu Li; Shu-Juan Lian; Dong-Yan Xu; Rong-Bo Guo (Environmental Science and Pollution Research, 2020)

The influence of flow rates and water depth gradients on the growth process of submerged macrophytes and the biomass composition of the phytoplankton assemblage in eutrophic water: an analysis based on submerged macrophytes photosynthesis parameters - Duo Xu; Yan Xia; Zhaoxin Li; Yonggang Gu; Chunhua Lou; Hao Wang; Jinlong Han (Environmental Science and Pollution Research, 2020)

The effects of micro- and meso-scale characteristics on the mechanical properties of coal-bearing sandstone - Qiangling Yao; Liqiang Yu; Xuehua Li; Kai Yan; Qiang Xu; Weinan Wang; Chuanjin Tang (Arabian Journal of Geosciences, 2020)

Bayesian prediction of potential depressions in the Erlian Basin based on integrated geophysical parameters - Feng-Jiao Xu; Chuan-Zhang Tang; Liang-Jun Yan; Qing-Li Chen; Guang-Ye Feng (Applied Geophysics, 2020)

Comparative analysis and natural evolution of squalene epoxidase in three Fritillaria species - Xu Lu; Lin-Ning Zhang; Jin-Fa Du; Xiao-Yan Zheng; Hui-Jun Li; Ping Li; Gui-Zhong Xin; Yan Jiang (Plant Molecular Biology, 2020)

Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress - Yu Liu; Guang-Jing Zou; Bo-Xuan Tu; Zhao-Lan Hu; Cong Luo; Yan-Hui Cui; Yang Xu; Fang Li; Ru-Ping Dai; Fang-Fang Bi; Chang-Qi Li (Neurotoxicity Research, 2020)

Characterization, tissue distribution of resistin gene and the effect of fasting and refeeding on resistin mRNA expression in Siberian sturgeon ( Acipenser baerii ) - Ni Tang; Yanlin Liu; Zhengzhi Tian; Shaoqi Xu; Mei Wang; Hu Chen; Bin Wang; Ya Li; Yan Wang; Song Yang; Liulan Zhao; Defang Chen; et al. (Journal of Fish Biology, 2020)
Resistin as an adipokine identified from rodents in 2001 is involved in many biological processes. However, little is known about this gene in fish. We cloned Siberian sturgeon ( Acipenser baerii ) resistin cDNA of 795 base pairs, encoding 107 amino acids, which showed 38–40% identity to human and rodents. Real‐time quantitative PCR showed that the resistin gene was widely distributed in tissues of Siberian sturgeon, with the highest expression in liver. After fasting for 1, 3, 6 and 10 days, the expression of the resistin gene in the liver of Siberian sturgeon decreased significantly, and after refeeding on the 10 days of fasting the resistin mRNA expression increased rapidly, suggesting that resistin may play an important role in liver in response to starvation. Taken together, these results suggest that resistin may be involved in the regulation of energy homeostasis in liver.

Beyond resource limitation: an expanded test of the niche dimension hypothesis for multiple types of niche axes - Xuebin Yan; Jeffrey Diez; Kailing Huang; Shaopeng Li; Xi Luo; Xinyu Xu; Fanglong Su; Lin Jiang; Hui Guo; Shuijin Hu (Oecologia, 2020)

Correlation Between CCG Polymorphisms and CAG Repeats During Germline Transmission in Chinese Patients with Huntington’s Disease - Hong-Rong Cheng; Xiao-Yan Li; Hui-Li Yu; Miao Xu; Yan-Bin Zhang; Shi-Rui Gan; Hong-Lei Li; Zhi-Ying Wu (Neuroscience Bulletin, 2020)

Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort - Wei-Wei Li; Zhen Wang; Dong-Yu Fan; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Ling Li; Heng Yang; Yu-Hui Liu; Xian-Le Bu; Wang-Sheng Jin; Fan Zeng; et al. (Neuroscience Bulletin, 2020)

The role of CTNNB1 and LEF1 in feather follicles development of Anser cygnoides and Anser anser - Yue Sun; Yuxuan Zhou; Petunia Msuthwana; Jing Liu; Chang Liu; Cornelius Tlotliso Sello; Yupu Song; Ziqiang Feng; Shengyi Li; Wei Yang; Yunpeng Xu; Xiaomin Yan; et al. (Genes & Genomics, 2020)

Pharmacokinetic Study of Ferulic Acid Following Transdermal or Intragastric Administration in Rats - Na Yan; Zhan Tang; Yuqi Xu; Xiumin Li; Qiao Wang (AAPS PharmSciTech, 2020)

A rapid and effective optical-clearing technique for deep tissue fluorescence imaging in trees - Liang Lu; Yangyang Cao; Qizouhong He; Wenchao Xu; Yan Zhang; Li Li; Ruili Li (Trees, 2020)

A study on the effects of salinity and pH on PSII function in mulberry seedling leaves under saline–alkali mixed stress - Zhang Huihui; Li Xin; Che Yan-hui; Wang Yue; Li Ma-bo; Yang Rong-yi; Xu Nan; Sun Guang-yu (Trees, 2020)

Changes in Starch Synthesis and Metabolism Within Developing Bulbs of Lycoris radiata During the Vegetative Growth Stage - Jun-xu Xu; Qing-zhu Li; Liu-yan Yang; Xin Li; Zhen Wang; Zhen Yang; Yong-chun Zhang (Journal of Plant Growth Regulation, 2020)

Elevated CO2 concentrations promote growth and photosynthesis of the brown alga Saccharina japonica - Xiansheng Zhang; Dong Xu; Zheng Guan; Shaohua Wang; Yan Zhang; Wei Wang; Xiaowen Zhang; Xiao Fan; Fang Li; Naihao Ye (Journal of Applied Phycology, 2020)

Correction to: Simulated microgravity significantly altered metabolism in epidermal stem cells - Bin-Bin Li; Zheng-Yang Chen; Nan Jiang; Song Guo; Jia-Qi Yang; Shao-Bin Chai; Hong-Feng Yan; Pei-Ming Sun; Gang Hu; Tao Zhang; Bing-Xin Xu; Hong-Wei Sun; et al. (In Vitro Cellular & Developmental Biology - Animal, 2020)

Plastic pollution in croplands threatens long‐term food security - Dan Zhang; Ee Ling Ng; Wanli Hu; Hongyuan Wang; Pablo Galaviz; Hude Yang; Wentao Sun; Chongxiao Li; Xingwang Ma; Bin Fu; Peiyi Zhao; Fulin Zhang; et al. (Global Change Biology, 2020)
Plastic pollution is a global concern given its prevalence in aquatic and terrestrial ecosystems. Studies have been conducted on the distribution and impact of plastic pollution in marine ecosystems, but little is known on terrestrial ecosystems. Plastic mulch has been widely used to increase crop yields worldwide, yet the impact of plastic residues in cropland soils to soil health and crop production in the long term remained unclear. In this paper, using a global meta‐analysis, we found that the use of plastic mulch can indeed increase crop yields on average by 25%–42% in the immediate season due to the increase of soil temperature (+8%) and moisture (+17%). However, the unabated accumulation of film residues in the field negatively impacts its physicochemical properties linked to healthy soil and threatens food production in the long term. It has multiple negative impacts on plant growth including crop yield (at the mean rate of −3% for every additional 100 kg/ha of film residue), plant height (−2%) and root weight (−5%), and soil properties including soil water evaporation capacity (−2%), soil water infiltration rate (−8%), soil organic matter (−0.8%) and soil available phosphorus (−5%) based on meta‐regression. Using a nationwide field survey of China, the largest user of plastic mulch worldwide, we found that plastic residue accumulation in cropland soils has reached 550,800 tonnes, with an estimated 6%–10% reduction in cotton yield in some polluted sites based on current level of plastic residue content. Immediate actions should be taken to ensure the recovery of plastic film mulch and limit further increase in film residue loading to maintain the sustainability of these croplands.

Effects of High-Fat Diet on Steatosis, Endoplasmic Reticulum Stress and Autophagy in Liver of Tilapia (Oreochromis niloticus) - Rui Jia; Li-Ping Cao; Jin-Liang Du; Qin He; Zheng-Yan Gu; Galina Jeney; Pao Xu; Guo-Jun Yin (Frontiers in Marine Science, 2020)

Plant abiotic stress response and nutrient use efficiency - Zhizhong Gong; Liming Xiong; Huazhong Shi; Shuhua Yang; Luis R. Herrera-Estrella; Guohua Xu; Dai-Yin Chao; Jingrui Li; Peng-Yun Wang; Feng Qin; Jijang Li; Yanglin Ding; et al. (Science China Life Sciences, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients - Huan-Yu Meng; Xi Li; Wan-Lin Jin; Cheng-Kai Yan; Xiao-Hua Dong; Qiu Xu; Yu-Yao Peng; Zhi-Bin Li; Yi Li; Zhao-Hui Luo; Li-Qun Xu; Huan Yang (European Journal of Clinical Pharmacology, 2020)

Geochemical features and potential environmental implications of heavy metals in mining-impacted sediments, south China - Bo Yan; Da-Mao Xu; Tao Chen; ZiAng Yan; Li-li Li (Environmental Science and Pollution Research, 2020)

Integrated fate assessment of aromatic amines in aerobic sewage treatment plants - Lin Jun Zhou; Zhi Yi Rong; Wen Gu; De Ling Fan; Ji Ning Liu; Li Li Shi; Yan Hua Xu; Zhi Ying Liu (Environmental Monitoring and Assessment, 2020)
The fate and exposure of chemicals in sewage treatment plants (STPs) are major considerations in risk assessment and environmental regulation. The biodegradability and removal of seven aromatic amines were systematically evaluated using a three-tiered integrated method: a standard ready biodegradability test, an aerobic sewage treatment simulation method, and model prediction. In tier 1, the seven aromatic amines were not readily biodegraded after 28 days. In adapted aerobic active sludge, 4-isopropyl aniline, 2,4-diaminotoluene, and 4-nitroaniline among them exhibited the degradation half-life time less than 20 h, the other four aromatic amines exhibited persistent with degradation half-life of > 60 h. In tier 2 of the aerobic sewage treatment simulation testing, 2,4-diaminotoluene, 4-nitroaniline, and 4-isopropylaniline demonstrated moderately to high overall removal. Hydraulic retention time (HRT) affects the removal with the optimum HRT was determined to be 12 h to 24. 2,6-Dimethyl aniline, 2-chloro-4-nitroaniline, 2,6-diethylaniline, and 3,4-dichloroaniline were not removed during the test, indicting these four aromatic amines will enter surface water and hence pose a potential risk to aquatic ecology. Considering the lack of an STP model in China for regulation purposes, in tier 3, we developed a Chinese STP (aerobic) (abbreviated as C-STP(O)) model that reflects a universal scenario for China to predict the fate. The predicted degradation, volatilization, and absorption showed a close relationship to the physicochemical properties of the chemicals, and had same tendency with tier 2 simulation test. The prediction showed that biodegradation rather than absorption or volatilization was the main removal process of aromatic amines in aerobic STP. With the combination of modified kinetics test with C-STP (O) model, the chemical fate can be more accurately predicted than using only the readily biodegradation result.

Human respiratory syncytial virus F protein expressed in Pichia pastoris or Escherichia coli induces protective immunity without inducing enhanced respiratory disease in mice - Hai Li; Lei Cao; Yan Zhang; Hu Ren; Peibei Zhao; Wenbo Xu (Archives of Virology, 2020)

Illumina MiSeq sequencing and network analysis the distribution and co-occurrence of bacterioplankton in Danjiangkou Reservoir, China - Zhao-Jin Chen; Ge Xu; Chuan-Yu Ding; Bao-Hai Zheng; Yan Chen; Hui Han; Yu-Ying Li; Jian-Wei Shi; Lan-Qun Hu (Archives of Microbiology, 2020)

Herbaceous layer determines the relationship between soil respiration and photosynthesis in a shrub-dominated desert plant community - Jie Ma; Ran Liu; Chenhua Li; Lianlian Fan; Guiqing Xu; Yan Li (Plant and Soil, 2020)

Central visual function and inner retinal structure in primary open-angle glaucoma - Li-juan Xu; Sha-ling Li; Vance Zemon; Yan-qian Xie; Yuan-bo Liang (Journal of Zhejiang University-SCIENCE B, 2020)

Photoprotection capacity of microalgae improved by regulating the antenna size of light-harvesting complexes - Guang-Rong Hu; Yong Fan; Yan-Lin Zheng; Feng Xu; Lei Zhang; Fu-Li Li (Journal of Applied Phycology, 2020)

Tracing solute sources and carbon dynamics under various hydrological conditions in a karst river in southwestern China - Jing Liu; Bo Chen; Zhu-Yan Xu; Yuan Wei; Zhi-Hua Su; Rui Yang; Yong-Xue Ji; Xiao-Dan Wang; Li-Li Zhang; Ning An; Fei Yang (Environmental Science and Pollution Research, 2020)

Identification and differential expression analysis of anthocyanin biosynthetic genes in root-skin color variants of radish (Raphanus sativus L.) - Rugang Yu; Xueling Du; Jing Li; Lan Liu; Chaomeng Hu; Xiaoling Yan; Yuqing Xia; Huijuan Xu (Genes & Genomics, 2020)

Novel ABCB1 and ABCC Transporters Are Involved in the Detoxification of Benzo(α)pyrene in Thick Shell Mussel, Mytilus coruscus - Baoying Guo; Zhongtian Xu; Xiaojun Yan; Isabella Buttino; Jiji Li; Chao Zhou; Pengzhi Qi (Frontiers in Marine Science, 2020)

QTL mapping for grain yield-related traits in bread wheat via SNP-based selective genotyping - Li Yang; Dehui Zhao; Zili Meng; Kaijie Xu; Jun Yan; Xianchun Xia; Shuanghe Cao; Yubing Tian; Zhonghu He; Yong Zhang (Theoretical and Applied Genetics, 2020)

Common Variant in TREM1 Influencing Brain Amyloid Deposition in Mild Cognitive Impairment and Alzheimer’s Disease - Yue-Song Liu; Wen-Jing Yan; Chen-Chen Tan; Jie-Qiong Li; Wei Xu; Xi-Peng Cao; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2020)

Scorpion Venom Heat-Resistant Peptide is Neuroprotective against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway - Xu-Gang Wang; Dan-Dan Zhu; Na Li; Yue-Lin Huang; Ying-Zi Wang; Ting Zhang; Chen-Mei Wang; Bin Wang; Yan Peng; Bi-Ying Ge; Shao Li; Jie Zhao (Neuroscience Bulletin, 2020)

Characterization of two novel Alu element-mediated α-globin gene cluster deletions causing α0-thalassemia by targeted next-generation sequencing - Zhiming Li; Xuan Shang; Shiqiang Luo; Fei Zhu; Xiaofeng Wei; Wanjun Zhou; Yuhua Ye; Tizhen Yan; Ren Cai; Xiangmin Xu (Molecular Genetics and Genomics, 2020)

Identification, characterization, and functional prediction of circular RNAs in maize - Yang Han; Xinxin Li; Yan Yan; Ming-Hua Duan; Jian-Hong Xu (Molecular Genetics and Genomics, 2020)

Simulated microgravity significantly altered metabolism in epidermal stem cells - Bin-Bin Li; Zheng-Yang Chen; Nan Jiang; Song Guo; Jia-Qi Yang; Shao-Bin Chai; Hong-Feng Yan; Pei-Ming Sun; Gang Hu; Tao Zhang; Bing-Xin Xu; Hong-Wei Sun; et al. (In Vitro Cellular & Developmental Biology - Animal, 2020)
Simulated microgravity can significantly affect various cell types and multiple systems of the human body, such as cardiovascular system, skeletal muscle system, and immune system, and is known to cause anemia and loss of electrolyte and fluids. Epidermal stem cells (EpSCs) were cultured in a rotary cell culture system (RCCS) bioreactor to simulate microgravity. The metabolites of EpSCs were identified by liquid chromatography-mass spectrometry (LC-MS). Compared with normal gravity (NG) group, a total of 57 different metabolites of EpSCs were identified ( P < 0.05, VIP > 1), including lipids and lipid-like molecules (51 molecules), amino acids (5 molecules), nucleosides, nucleotides, and analogues (1 molecule). According to the partial least squares discriminant analysis (PLS-DA) score plot, a VIP > 1 and P < 0.05 were obtained for the 57 different metabolites, of which 23 molecules were significantly downregulated and 34 were significantly upregulated in simulated microgravity (SMG) group. These results showed that SMG has a significant impact on different pathways, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis indicated that multiple pathways were involved, mainly the amino acid metabolism pathway, lipid metabolism pathway, membrane transport pathway, and cell growth and death pathways. Thus, the metabolic profile of EpSCs was changed under SMG. Exploring the metabolic profile of EpSCs would be helpful to further understand the growth characteristics of EpSCs under SMG, which will provide a new approach to explore the metabolomics mechanism of stress injury and repair trauma under SMG.

Developmental basis for flower sex determination and effects of cytokinin on sex determination in Plukenetia volubilis (Euphorbiaceae) - Yan Luo; Bang-Zhen Pan; Lu Li; Chen-Xuan Yang; Zeng-Fu Xu (Plant Reproduction, 2020)
Key message Cytokinin might be an important factor to regulate floral sex at the very early stage of flower development in sacha inchi. Abstract Sacha inchi ( Plukenetia volubilis , Euphorbiaceae) is characterized by having female and male flowers in a thyrse with particular differences. The mechanisms involved in the development of unisexual flowers are very poorly understood. In this study, the inflorescence and flower development of P. volubilis were investigated using light microscopy and scanning electron microscopy. We also investigated the effects of cytokinin on flower sex determination by exogenous application of 6-benzyladenine (BA) in P. volubilis . The floral development of P. volubilis was divided into eight stages, and the first morphological divergence between the male and female flowers was found to occur at stage 3. Both female and male flowers can be structurally distinguished by differences in the shape and size of the flower apex after sepal primordia initiation. There are no traces of gynoecia in male flowers or of androecia in female flowers. Exogenous application of BA effectively induced gynoecium primordia initiation and female flower development, especially at the early flower developmental stages. We propose that flower sex is determined earlier and probably occurs before flower initiation, either prior to or at inflorescence development due to the difference in the position of the female and male primordia in the inflorescence and in the time of the female and male primordia being initiated. The influence of cytokinin on female primordia during flower development in P. volubilis strongly suggests a feminization role for cytokinin in sex determination. These results indicate that cytokinin could modify the fate of the apical meristem of male flower and promote the formation of carpel primordia in P. volubilis.

A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus - Yan Wang; Xuejiao Cui; Xu Chen; Shixing Yang; Yu Ling; Qianben Song; Su Zhu; Luying Sun; Chuang Li; Yu Li; Xutao Deng; Eric Delwart; et al. (Archives of Virology, 2020)

Ectopic expression of IiSHP2 from Isatis indigotica Fortune, a PLE-lineage MADS-box gene, influences leaf, floral organ and silique morphology in Arabidopsis thaliana - Meng-Xin Lu; Dian-Zhen Li; Zuo-Qian Pu; Yan-Qin Ma; Xuan Huang; Zi-Qin Xu (Physiology and Molecular Biology of Plants, 2020)

Alternative complement pathway is activated in the brains of scrapie-infected rodents - Cao Chen; Yan Lv; Chao Hu; Xiao-Feng Xu; Ren-Qing Zhang; Kang Xiao; Yue Ma; Li-Ping Gao; Jian-Le Li; Qiang Shi; Jing Wang; Qi Shi; et al. (Medical Microbiology and Immunology, 2020)

Roles of PTBP1 in alternative splicing, glycolysis, and oncogensis - Wei Zhu; Bo-lun Zhou; Li-juan Rong; Li Ye; Hong-juan Xu; Yao Zhou; Xue-jun Yan; Wei-dong Liu; Bin Zhu; Lei Wang; Xing-jun Jiang; Cai-ping Ren (Journal of Zhejiang University-SCIENCE B, 2020)

The expression and role of PIDD in retina after optic nerve crush - Fen Tang; Fan Xu; Ling Cui; Wei Huang; Li Jiang; Lifei Chen; Wenya Yan; Wenjing He; Chaolan Shen; Hui Huang; Jian Lv; Xin Zhao; et al. (Journal of Molecular Histology, 2020)

Effect of CSE on M1/M2 polarization in alveolar and peritoneal macrophages at different concentrations and exposure in vitro - Haoshen Feng; Yan Yin; Yuan Ren; Menglu Li; Dan Zhang; Mingtao Xu; Xu Cai; Jian Kang (In Vitro Cellular & Developmental Biology - Animal, 2020)

Application of metagenomic next-generation sequencing for bronchoalveolar lavage diagnostics in critically ill patients - Ying Li; Bing Sun; Xiao Tang; Ya-lan Liu; Hang-yong He; Xu-yan Li; Rui Wang; Fei Guo; Zhao-hui Tong (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Sedimentary records of nitrogen isotope in the western tropical Pacific linked to the eastern tropical Pacific denitrification during the last deglacial time - Xiaowei Zhu; Guodong Jia; Weihai Xu; Xufeng Zheng; Jianguo Liu; Yuhang Tian; Li Miao; Wen Yan (Geo-Marine Letters, 2020)

Regulatory function of EARLI1-LIKE HYBRID PROLINE-RICH PROTEIN 1 in the floral transition of Arabidopsis thaliana - Zhen Du; Li Zhang; Na Tian; Meng-Xin Lu; Yan-Qin Ma; Jing-Wen Yao; Michael Schläppi; Zi-Qin Xu (Acta Physiologiae Plantarum, 2020)

The false smut pathogen Ustilaginoidea virens requires rice stamens for false smut ball formation - Jing Fan; Jie Liu; Zhi‐You Gong; Pei‐Zhou Xu; Xiao‐Hong Hu; Jin‐Long Wu; Guo‐Bang Li; Juan Yang; Yu‐Qiu Wang; Yu‐Feng Zhou; Shuang‐Cheng Li; Li Wang; et al. (Environmental Microbiology, 2020)
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The disease is characterized by the transformation of individual rice florets into false smut balls, which is caused by the fungal pathogen Ustilaginoidea virens . To date, little is known about the host factors required for false smut ball formation by U . virens . In this study, we identified histological determinants for the formation of false smut balls by inoculating U . virens into rice floral mutants defective with respect to individual floral parts. The results showed that U . virens could form mature false smut balls in rice floral mutants with defective pistils, but failed to develop false smut balls in the superwoman mutant lacking stamens, identifying that U . virens requires rice stamens to complete its infection cycle. Comparative transcriptome analysis indicated a list of candidate host genes that may facilitate nutrient acquisition by U . virens from the rice stamens, such as SWEET11 , SWEET14 and SUT5 , and genes involved in the biosynthesis of trehalose and raffinose family sugars. These data pinpoint rice stamens as the key target organ of U . virens infection and provide a valuable starting point for dissecting the molecular mechanism of false smut ball formation.

Marker-free lines of phytase-transgenic Brassica napus show enhanced ability to utilize phytate - Li Xu; Lingyi Zeng; Li Ren; Wang Chen; Fan Liu; Huan Yang; Ruibing Yan; Kunrong Chen; Xiaoping Fang (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Adjuvant therapy with Astragalus membranaceus for post-stroke fatigue: a systematic review - Li Xu; Xiao-Yan Xu; Xue-Qin Hou; Fu-Gang Wang; Shan Gao; Han-Ting Zhang (Metabolic Brain Disease, 2020)

Correction to: Arsenic concentration, speciation, and risk assessment in sediments of the Xijiang River basin, China - Hai-bo Wang; Jia-ming Xu; Mario Alberto Gomez; Zhong-liang Shi; Shi-feng Li; Shu-yan Zang (Environmental Monitoring and Assessment, 2020)

Fuzzy comprehensive evaluation of debris flow in Matun village, Laomao Mountain area, Dalian city - Shen Shiwei; Xie He’En; Xu Yan; Zhang Min; Niu Xiaobin; Li Guoliang (Arabian Journal of Geosciences, 2020)

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages - Di Chen; Xiang-Yu Xu; Rui Li; Gen-Ao Zang; Yue Zhang; Ming-Rui Wang; Meng-Fei Xiong; Jia-Rui Xu; Ting Wang; Hui Fu; Qin Hu; Bin Wu; et al. (AAPS PharmSciTech, 2020)

Cloning and Expression Analysis of the ScD53 Gene from Sugarcane - Ai-Li Lv; Xu-Juan Li; Chun-Jia Li; Hong-Bo Liu; Qiu-Yan Zi; Xiu-Qin Lin; Xin-Long Liu (Sugar Tech, 2019)

Elevated temperature increased nitrification activity by stimulating AOB growth and activity in an acidic paddy soil - Qian Zhang; Yong Li; Yan He; Philip C. Brookes; Jianming Xu (Plant and Soil, 2019)

RETRACTED ARTICLE: Resibufogenin suppresses tumor growth and inhibits glycolysis in ovarian cancer by modulating PIM1 - Qian Li; Chuanwu Jiang; Yan Wang; Minghua Wei; Huijin Zheng; Yanqi Xu; Xuegang Xu; Fengyu Jia; Kai Liu; Gang Sun; Jianhua Zang; Ping Mo (Naunyn-Schmiedeberg's Archives of Pharmacology, 2019)

Metabolomic profiling on rat brain of prenatal malnutrition: implicated for oxidative stress and schizophrenia - Fei Xu; Xin Li; Weibo Niu; Gaini Ma; Qianqian Sun; Yan Bi; Zhenming Guo; Decheng Ren; Jiaxin Hu; Fan Yuan; Ruixue Yuan; Lei Shi; et al. (Metabolic Brain Disease, 2019)

PGE2 facilitates tail regeneration via activation of Wnt signaling in Gekko japonicus - Man Xu; Tiantian Wang; Wenjuan Li; Yin Wang; Yanran Xu; Zuming Mao; Ronghua Wu; Mei Liu; Yan Liu (Journal of Molecular Histology, 2019)

Research on Support of Deformation of Mining Side Gob Along High-Stress Mining Roadway - Yanhui Li; Limin Liu; Jiaxin Sun; Yang Li; Xu Yan (Geotechnical and Geological Engineering, 2019)

Paramyxoviruses respiratory syncytial virus, parainfluenza virus, and human metapneumovirus infection in pediatric hospitalized patients and climate correlation in a subtropical region of southern China: a 7-year survey - Wen-Kuan Liu; De-Hui Chen; Wei-Ping Tan; Shu-Yan Qiu; Duo Xu; Li Zhang; Shu-Jun Gu; Rong Zhou; Qian Liu (European Journal of Clinical Microbiology & Infectious Diseases, 2019)

Differences of physical vs. psychological stress: evidences from glucocorticoid receptor expression, hippocampal subfields injury, and behavioral abnormalities - Yuefeng Li; Jiasheng Qin; Jinchuan Yan; Ningning Zhang; Yuhao Xu; Yan Zhu; Liangju Sheng; Xiaolan Zhu; Shenghong Ju (Brain Imaging and Behavior, 2019)

Chronology of coastal aeolian deposition and its paleoenvironmental implications on the Liuao Peninsula of South China - Jian-hui Jin; Zhi-zhong Li; Zhi-yong Ling; Fei Zheng; Xiao-lin Xu; Yan Cheng; Xiang-dong Cao; Zhi-xing Li; Wen-jing Zhang; Yong-qing Ren (Journal of Mountain Science, 2019)

Prediction of Suitable Habitat for Lycophytes and Ferns in Northeast China: A Case Study on Athyrium brevifrons - Yan Li; Wei Cao; Xingyuan He; Wei Chen; Sheng Xu (Chinese Geographical Science, 2019)

Optimization of Immunization Procedure for Eimeria tenella DNA Vaccine pVAX1-pEtK2-IL-2 and Its Stability - Bucai Zhang; Cheng Yuan; Xiaokai Song; Lixin Xu; Ruofeng Yan; Muhammad Ali A. Shah; Changming Guo; Shanyuan Zhu; Xiangrui Li (Acta Parasitologica, 2019)

Multi‐model analysis of climate impacts on plant photosynthesis in China during 2000–2015 - Hao Yan; Shao‐Qiang Wang; Jun‐Bang Wang; Yun Cao; Ling‐Ling Xu; Men‐Xin Wu; Lu Cheng; Liu‐Xi Mao; Feng‐Hua Zhao; Xian‐Zhou Zhang; Yun‐Fen Liu; Yan‐Fen Wang; et al. (International Journal of Climatology, 2019)
Differences, arising from differences in gross primary production (GPP) model structures and driving forces, have fuelled arguments concerning interannual changes of GPP in China since 2000. To better investigate the interannual variability of GPP and its covariance with climate factors in China, this study adopted a multi‐model analysis based on three GPP models (i.e., Terrestrial Ecosystem Carbon flux model [TEC], Breathing Earth System Simulator model [BESS], and MOD17 GPP model). The results show that annual GPP in China increased by 0.021–0.057 Pg C year −1 from 2000 to 2015 attributable to atmospheric‐CO 2 fertilization effects and favourable climate change, that is, increasing precipitation ( P r ) and temperature ( T a ). However, northern China and southern China had a large difference in the amplitude of these GPP changes; annual GPP increased by 0.017–0.039 Pg C year −1 in northern China but only 0.001–0.018 Pg C year −1 in southern China. Northern China and southern China occupy contrasting climate zones and this contrast produced different interannual variability of GPP through different mechanisms. Northern China has a dry climate with GPP changes sensitive to P r . As a result, more P r along with higher T a in northern China produced the strong uptrend of GPP from 2000 to 2015. In contrast, southern China has a wet climate with its GPP sensitive to solar radiation and T a . For the interval of 2000–2015, decreasing radiation plus drought exerted a negative influence on GPP in southern China. This study highlights the diverse mechanisms in which climate change affects GPP in dry and wet climate zones. A robust multi‐model analysis is preferred to reduce uncertainties arising from a single GPP model and its driving data.

Chitin synthase is involved in vegetative growth, asexual reproduction and pathogenesis of Phytophthora capsici and Phytophthora sojae - Wei Cheng; Menglan Lin; Min Qiu; Liang Kong; Yuanpeng Xu; Yaning Li; Yan Wang; Wenwu Ye; Suomeng Dong; Shuilin He; Yuanchao Wang (Environmental Microbiology, 2019)
Summary Chitin is a structural and functional component of the fungal cell wall and also serves as a pathogen‐associated molecular pattern (PAMP) that triggers the innate immune responses of host plants. However, no or very little chitin is found in the fungus‐like oomycetes. In Phytophthora spp., the presence of chitin has not been demonstrated so far, although putative chitin synthase (CHS) genes, which encode the enzymes that synthesize chitin, are present in their genomes. Here, we revealed that chitin is present in the zoospores and released sporangia of Phytophthora , and this is most consistent with the transcriptional pattern of PcCHS in Phytophthora capsici and PsCHS1 in Phytophthora sojae . Disruption of the CHS genes indicated that PcCHS and PsCHS1 , but not PsCHS2 (which exhibited very weak transcription), have similar functions involved in mycelial growth, sporangial production, zoospore release and the pathogenesis of P. capsici and P. sojae . We also suggest that chitin in the zoospores of P. capsici can act as a PAMP that is recognized by the chitin receptors AtLYK5 or AtCERK1 of Arabidopsis . These results provide new insights into the biological significance of chitin and CHSs in Phytophthora and help with the identification of potential targets for disease control.

Spontaneous mutations in FgSAD1 suppress the growth defect of the Fgprp4 mutant by affecting tri‐snRNP stability and its docking in Fusarium graminearum - Xiaoping Li; Zhili Fan; Ming Yan; Jia Qu; Jin‐Rong Xu; Qiaojun Jin (Environmental Microbiology, 2019)
Summary FgPrp4, the only kinase in the spliceosome, is not essential for viability, but is important for splicing efficiency in Fusarium graminearum . The Fgprp4 deletion mutant had severe growth defects but often produced spontaneous suppressors with faster growth rate. To better understand the suppression mechanism, we identified and characterized spontaneous mutations in the tri‐snRNP‐specific protein, FgSad1, which suppressed the growth defects of Fgprp4 . The L512P mutation was verified for its suppressive effects on Fgprp4 , suggesting that mutations in FgSad1 may have effects involving FgPrp4 phosphorylation on FgSad1. Phosphoproteomics analysis showed that FgSad1 may not be the direct substrate of FgPrp4 kinase. Furthermore, truncation analysis showed that the N‐terminal, extra RS‐rich region of FgSad1 is critical for its function and is post‐translationally modified. The P258S or S269P mutations in FgSad1 increased its interactions with the U5 protein FgPrp8 and the U4/U6 protein FgPrp31, which may result in tri‐snRNP stabilization. Additionally, the D76N mutation increased the association of FgSad1 with the U2 snRNP. These data indicate that suppressor mutations in FgSad1 increase the stability of the tri‐snRNP and/or the affinity of FgSad1 with U2 snRNP and therefore potentially facilitate the docking of tri‐snRNP into the spliceosome.

Seasonal variation in the groundwater dependency of two dominant woody species in a desert region of Central Asia - Xue Wu; Xin-Jun Zheng; Xin-Wei Yin; Yue-Meng Yue; Ran Liu; Gui-Qing Xu; Yan Li (Plant and Soil, 2019)

RETRACTED ARTICLE: Downregulation of long non-coding RNA TUG1 suppresses tumor growth by promoting ubiquitination of MET in diffuse large B-cell lymphoma - Hai Cheng; Zhiling Yan; Xue Wang; Jiang Cao; Wei Chen; Kunming Qi; Dian Zhou; Jieyun Xia; Na Qi; Zhenyu Li; Kailin Xu (Molecular and Cellular Biochemistry, 2019)

Arsenic concentration, speciation, and risk assessment in sediments of the Xijiang River basin, China - Hai-bo Wang; Jia-ming Xu; Mario Alberto Gomez; Zhong-liang Shi; Shi-feng Li; Shu-yan Zang (Environmental Monitoring and Assessment, 2019)

Land–atmosphere interaction over the Indo-China Peninsula during spring and its effect on the following summer climate over the Yangtze River basin - Chujie Gao; Haishan Chen; Gen Li; Hedi Ma; Xinyu Li; Shangmin Long; Bei Xu; Xing Li; Xinmin Zeng; Hong Yan; Ziqian Wang; Song Yang (Climate Dynamics, 2019)

Three new labdane-type diterpenoids from Callicarpa macrophylla Vahl. - Zhen-Hui Wang; Huan-Jun Xu; Yang-Yang Zhai; Lan-Ping Yang; Qiang Li; Mei Huang; Xing-Ying Chen; Wen-Kui Zhang; Yue-Li Meng; Qing-Ling Zhang; Chao Niu; Yan-Ru Zhang (Natural Product Research, 2019)

Resource (Light and Nitrogen) and Density-Dependence of Seaweed Growth - Xi Xiao; Susana Agusti; Fang Lin; Caicai Xu; Yan Yu; Yaoru Pan; Ke Li; Jiaping Wu; Carlos M. Duarte (Frontiers in Marine Science, 2019)

HSP70 improves the viability of cryopreserved Paeonia lactiflora pollen by regulating oxidative stress and apoptosis-like programmed cell death events - Ruifen Ren; Xueru Jiang; Wei Di; Zedi Li; Bingling Li; Jin Xu; Yan Liu (Plant Cell, Tissue and Organ Culture (PCTOC), 2019)

Association of the Polygenic Risk Score with the Incidence Risk of Parkinson’s Disease and Cerebrospinal Fluid α-Synuclein in a Chinese Cohort - Wei-Wei Li; Dong-Yu Fan; Ying-Ying Shen; Fa-Ying Zhou; Yang Chen; Ye-Ran Wang; Heng Yang; Jing Mei; Ling Li; Zhi-Qiang Xu; Yan-Jiang Wang (Neurotoxicity Research, 2019)

Genetic Association Between NGFR, ADAM17 Gene Polymorphism, and Parkinson’s Disease in the Chinese Han Population - Wei-Wei Li; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Qian-Qian Shi; Jing Mei; Heng Yang; Fa-Ying Zhou; An-Yu Shi; Tao Zhang; Xiu-Qing Yao; Zhi-Qiang Xu; et al. (Neurotoxicity Research, 2019)

Effects of temperature and salinity on the growth and biochemical composition of the brown alga Sargassum fusiforme (Fucales, Phaeophyceae) - Jingyu Li; Yingchao Liu; Yan Liu; Qiaohan Wang; Xu Gao; Qingli Gong (Journal of Applied Phycology, 2019)

Imaging aquatic animal cells and associated pathogens by atomic force microscopy in air - Chen Li; Yan Liang; Menglin Xu; Hailiang Wang; Chongming Wang; Jie Huang (Biotechnology Letters, 2019)

Brain structural basis of individual variability in dream recall frequency - Shuqin Zhou; Jing Xu; Zihui Su; Yuezhen Li; Yan Shao; Hongqiang Sun; Huaiqiu Zhu; Qihong Zou; Jia-Hong Gao (Brain Imaging and Behavior, 2019)

Identification of the optimal insertion site for expression of a foreign gene in an infectious hematopoietic necrosis virus vector - Jing-Zhuang Zhao; Li-Ming Xu; Miao Liu; Yong-Sheng Cao; Jia-Sheng Yin; Hong-Bai Liu; Tong-Yan Lu; Zhen-Yu Zhang (Archives of Virology, 2019)

Molecular characterization of a new badnavirus infecting green Sichuan pepper (Zanthoxylum schinifolium) - Min Xu; Song Zhang; Zhiyou Xuan; Jiaxing Wu; Peng Dong; Yan Zhou; Ruhui Li; Mengji Cao (Archives of Virology, 2019)

Optically stimulated luminescence ages of the Hengyu site and their implications for anthropogenic activities in the Fuzhou Basin, South China - Jianhui Jin; Yunming Huang; Yong Zhang; Zhizhong Li; Xuechun Fan; Zhiyong Ling; Fei Zheng; Yan Cheng; Xiaolin Xu; Zhixing Li; Wenjing Zhang (Journal of Quaternary Science, 2019)
The chronologies of few Neolithic sites in the lower reaches of the Min River of China have been well investigated for the middle to late Holocene. In this study, the Hengyu Neolithic site in Fujian Province, South China, which has significant archaeological remains, was dated using blue‐stimulated optically stimulated luminescence (OSL) and accelerator mass spectrometry radiocarbon (AMS 14 C) techniques. The results, comprising nine OSL and three AMS 14 C ages through the Neolithic sequence, provide new evidence towards understanding the relationship between environmental evolution and human activities in the middle to late Holocene in the Fuzhou Basin and coastal areas of South China. The ages of the site deposits vary from 6.83 to 1.67 ka and can be divided into two main phases: the Keqiutou–Tanshishan culture period and the Bronze culture period. In contrast, the persistent periods of ancient human activities at the Hengyu site seem to correspond to regional sea‐level changes and the East Asian winter monsoon as a secondary factor, which can affect human activities through sea‐level impacts. The warm and high sea level conditions provided a liveable environment for the ancient humans of Fujian and even South China. The ages of two building column bases are linked to the early stage of the Han dynasty, suggesting a potentially favourable habitation environment; that is, ancient humans occupied and settled this area for the long term within this time period, which is consistent with sea‐level changes and palynology records. Copyright © 2019 John Wiley & Sons, Ltd.

Inventory Theory-Based Stochastic Optimization for Reservoir Water Allocation - Yaowen Xu; Qiang Fu; Yan Zhou; Mo Li; Yi Ji; Tianxiao Li (Water Resources Management, 2019)

Transcriptomic analysis of Chinese wild Vitis pseudoreticulata in response to Plasmopara viticola - Ruiqi Liu; Kai Weng; Mengru Dou; Tingting Chen; Xiao Yin; Zhiqian Li; Tiemei Li; Chen Zhang; Gaoqing Xiang; Guotian Liu; Yan Xu (Protoplasma, 2019)

N, N’-disubstitutedphenyl-4-ethoxyl benzene-1, 3-disulfonamides: design, synthesis, and evaluation of anti-platelet aggregation activity - Xin Chen; Xiujie Liu; kai Qiu; Xiang Xu; Caiwen Li; Yan Wang (Medicinal Chemistry Research, 2019)

Exosomes from patients with Parkinson’s disease are pathological in mice - Chao Han; Nian Xiong; Xingfang Guo; Jinsha Huang; Kai Ma; Ling Liu; Yun Xia; Yan Shen; Jie Li; Haiyang Jiang; Luxi Wang; Shiyi Guo; et al. (Journal of Molecular Medicine, 2019)

Cytotoxic abietane and kaurane diterpenoids from Celastrus orbiculatus - Wei Jiang; Ti-Zhuang Shan; Jia-Jun Xu; Wen-Ju Chen; Li Miao; Meng-Ying Lv; Li Tao; Yan-Qing Liu (Journal of Natural Medicines, 2019)

Detection and characterization of a novel hepacivirus in long-tailed ground squirrels (Spermophilus undulatus) in China - Li-li Li; Meng-meng Liu; Shu Shen; Yu-jiang Zhang; Ya-long Xu; Hong-yan Deng; Fei Deng; Zhao-jun Duan (Archives of Virology, 2019)

Early Cretaceous gold mineralization in the Lesser Xing’an Range of NE China: the Yongxin example - Zhong-Hai Zhao; Jing-Gui Sun; Guang-Hui Li; Wen-Xi Xu; Chang-Lu Lü; Song Wu; Yan Guo; Jin Liu; Liang Ren (International Geology Review, 2019)

Contribution of methylation regulation of MpDREB2A promoter to drought resistance of Mauls prunifolia - Xuewei Li; Yinpeng Xie; Liyuan Lu; Mingjia Yan; Nan Fang; Jidi Xu; Liping Wang; Yan Yan; Tao Zhao; Steve van Nocker; Fengwang Ma; Dong Liang; et al. (Plant and Soil, 2019)

Proton Oriented-“Smart Depot” for Responsive Release of Ca2+ to Inhibit Peptide Acylation in PLGA Microspheres - Jiwei Liu; Yan Xu; Yonglu Wang; Hao Ren; Zhengjie Meng; Kuntang Liu; Zhe Liu; He Huang; Xueming Li (Pharmaceutical Research, 2019)

Correction to: Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain - Yang Li; Jing Liu; Xu Liu; Cun-Jin Su; Qi-Lin Zhang; Zhi-Hong Wang; Lei-Fang Cao; Xue-Yan Guo; Ya Huang; Weifeng Luo; Tong Liu (Neuroscience Bulletin, 2019)