Regulatory role of miR-129 and miR-384-5p on apoptosis induced by oxygen and glucose deprivation in PC12 cell - Hui-Lin Guan; Yue Guan; Wen-Yuan Li; Jia-Wei Liu; Yu-Jia Zheng; Yan-Zhong Guan; Hong-Feng Liu; Li-Xin Guan; Feng-Guo Zhai (Experimental Brain Research, 2022)

Isotherm, kinetics, and adsorption mechanism studies of diethylenetriaminepentaacetic acid—modified banana/pomegranate peels as efficient adsorbents for removing Cd(II) and Ni(II) from aqueous solution - Fanghui Wang; Peng Wu; Lin Shu; Qingbin Guo; Di Huang; Huanhuan Liu (Environmental Science and Pollution Research, 2022)

First result of GNSS-R-based sea level retrieval with CMC and its combination with the SNR method - Zhiyu Zhang; Fei Guo; Xiaohong Zhang; Lin Pan (GPS Solutions, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Productivity calculating method in tight gas reservoirs considering the stress sensitivity - Jie He; Xiangdong Guo; Hongjun Cui; Kaiyu Lei; Yanyun Lei; Lin Zhou; Qinghai Liu; Yushuang Zhu; Linyu Liu (Arabian Journal of Geosciences, 2022)

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Evolutionary characteristics and phylogeny of cotton chloroplast tRNAs - Ning Wang; Wan-Lin Dong; Xiao-Jing Zhang; Tong Zhou; Xiao-Juan Huang; Bao-Guo Li; Jian-Ni Liu; Xiong-Feng Ma; Zhong-Hu Li (Planta, 2021)

LncRNA-SNHG16 promotes proliferation and migration of acute myeloid leukemia cells via PTEN/PI3K/AKT axis through suppressing CELF2 protein - Min Shi; Ruili Yang; Jing Lin; Qi Wei; Lei Chen; Weifeng Gong; Yang Li; Xiaobo Guo (Journal of Biosciences, 2021)

External evaluation of published population pharmacokinetic models of polymyxin B - Ya-qian Li; Kai-feng Chen; Jun-jie Ding; Hong-yi Tan; Nan Yang; Ya-qi Lin; Cui-fang Wu; Yue-liang Xie; Guo-ping Yang; Jing-Jing Liu; Qi Pei (European Journal of Clinical Pharmacology, 2021)

Occurrence, source apportionment, and carcinogenic risk assessment of polycyclic aromatic hydrocarbons in urban road dusts in Shanghai - Xue-Tong Wang; Rui Fu; Ying Zhou; Cheng-Lin Wang; Guo-Fa Ren; Xiao-Li Wang; Hui Li (Environmental Science and Pollution Research, 2021)

Distribution characteristics of per- and polyfluoroalkyl substances (PFASs) in human urines of acrylic fiber plant and chemical plant - Lin Peng; Wang Xu; Qinghuai Zeng; Yao Cheng; Yingjie Zhang; Ying Guo; Da Chen; Chao Jiang; Fei Wang (Environmental Science and Pollution Research, 2021)

Persistent pollution episodes, transport pathways, and potential sources of air pollution during the heating season of 2016–2017 in Lanzhou, China - Yongtao Guo; Chunying Lin; Jiangping Li; Lingbo Wei; Yuxia Ma; Qidong Yang; Dandan Li; Hang Wang; Jiahui Shen (Environmental Monitoring and Assessment, 2021)

Long-term changes of water acidity in an intact forested watershed in south China - Xiao-dong Liu; Ying-jie Feng; Qi-feng Mo; Guo-wei Chu; Yue-lin Li; Qian-mei Zhang; Wei-qiang Zhang; Xian-hua Gan; Qing Zhou (Journal of Mountain Science, 2021)

Negative‐pressure irrigation improves water and fertilizer use efficiencies and fruit yield of greenhouse tomato on the North China Plain* - Yinkun Li; Xuzhang Xue; Fan Xu; Wenzhong Guo; Minjie Duan; Sen Lin; Youli Li; Zhan Wang (Irrigation and Drainage, 2021)
Water and fertilizer supply are the main factors limiting greenhouse vegetable production on the North China Plain. This study tested the hypothesis that negative‐pressure irrigation is advantageous for reducing water and fertilizer application compared with drip irrigation in a greenhouse. Three treatments (drip irrigation + optimal fertilizer [DOF], drip irrigation + Yamazaki tomato nutrient solution [DNS], and negative‐pressure irrigation + Yamazaki tomato nutrient solution [NNS]) were applied in a greenhouse tomato double‐cropping system conducted in consecutive spring–summer and autumn–winter seasons. Soil moisture content, nitrate‐nitrogen (N) concentration, fruit yield, total N uptake ( N u ), irrigation water productivity, and partial factor productivity of applied fertilizer were analysed. The seasonal variation of soil moisture and nitrate‐N contents in the 0–20‐cm soil layer for NNS treatment was stable. Nitrate‐N accumulated after the final harvest in the autumn–winter season of NNS treatment was significantly less than under DOF and DNS. Despite lower water and nutrient inputs, NNS showed higher N u and fruit yield than DOF and DNS. These results demonstrated that negative‐pressure irrigation can reduce irrigation water and nutrient inputs and nitrate‐N accumulation in the soil, and significantly improve water and fertilizer use efficiency in greenhouse‐grown tomato compared with those under drip irrigation.

Tibetan Plateau v ortex‐associated precipitation and its link with the Tibetan Plateau heating anomaly - Zhiqiang Lin; Weidong Guo; Xiuping Yao; Jun Du; Wenkai Li; Jun Ge (International Journal of Climatology, 2021)
The Tibetan Plateau (TP) is known as the Asian water tower that supplies fresh water for millions of people in Asia. The Tibetan Plateau vortices (TPVs) are one of the major precipitation‐producing weather systems over the TP. The characteristics of TPV‐associated precipitation from 1979 to 2017 are quantitatively analysed based on three daily precipitation datasets. The influence of TPVs on precipitation is more significant in the warm season (May–September) because the precipitation and TPV activities both peak in the warm season. The TPV‐associated precipitation (VAP) dominates the total precipitation over most of the TP in the warm season. The VAP contributes more than 50% of the total precipitation in the warm season over 30% of the area over the TP, particularly in the central TP, while the VAP accounts for more than 25% of the total precipitation in the cold season over about 20% of the area over the TP. Therefore, TPVs are the major systems to produce precipitation on the TP in the warm season, and they are also important in the cold season in certain regions. The interannual variation of VAP is mainly determined by the number, rather than the precipitation intensity, of TPVs. Furthermore, the heating anomaly caused by the TP thermodynamic effect is an influential factor of VAP. Stronger (weaker) TP heating and resulting ascending motion strengthen (attenuate) the convergence near the TP surface and the divergence in the upper troposphere. The thermal adaption‐associated circulation generates more (less) TPVs and VAP.

Associations of bisphenol exposure with the risk of gestational diabetes mellitus: a nested case–control study in Guangxi, China - Peng Tang; Jun Liang; Qian Liao; Huishen Huang; Xiaojing Guo; Mengrui Lin; Bihu Liu; Bincai Wei; Xiaoyun Zeng; Shun Liu; Dongping Huang; Xiaoqiang Qiu (Environmental Science and Pollution Research, 2021)

In situ geochemistry and Fe–O isotopic composition of iron oxides from the Pha Lek Fe deposit, northwest Truong Son orogenic belt, Laos: implications for ore-forming processes - Lin Hou; Linnan Guo; Siwei Xu; Qiming Zhang; Xiangting Zeng (Mineralium Deposita, 2021)

Evaluation of the antifungal activity of Lysurus mokusin extract against Pestalotiopsis neglecta and GC–MS analysis of the active components - Lian-Nan Lin; Jing Yang; Guo-Cai Zhang; Xiao-Bo Zhang; Ting-Yu Wang; De-Dong Wu (Journal of Plant Pathology, 2021)

Carbon consumption and adsorption-regeneration of H2S on activated carbon for coke oven flue gas purification - Yuting Lin; Yuran Li; Zhicheng Xu; Junxiang Guo; Tingyu Zhu (Environmental Science and Pollution Research, 2021)

Spatiotemporal change of vegetation coverage recovery and its driving factors in the Wenchuan earthquake-hit areas - Xiao-fei Sun; Lin-guo Yuan; Ying-zhi Zhou; Huai-yong Shao; Xian-feng Li; Ping Zhong (Journal of Mountain Science, 2021)

Late Cretaceous adakitic rocks from the western Tibetan Plateau: implications for the subduction of the Neo-Tethys Ocean - Wei Wang; Qing-Guo Zhai; Pei-Yuan Hu; Sun-Lin Chung; Yue Tang; Hai-Tao Wang; Zhi-Cai Zhu; Hao Wu; Zhi-Qiang Huang (International Geology Review, 2021)

The effects of initial deviatoric stress on anisotropy of marine clay and strain components - Heng Zhuang; Mingfeng Li; Chaoliang Wang; Lin Guo; Dikang Zhang; Hongke Du; Yunguo Du (Marine Georesources & Geotechnology, 2021)

Correction to: Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering - Ya Tang; Jialiang Tian; Long Li; Lin Huang; Quan Shen; Shanzhu Guo; Yue Jiang (Tissue Engineering and Regenerative Medicine, 2021)

Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering - Ya Tang; Jialiang Tian; Long Li; Lin Huang; Quan Shen; Shanzhu Guo; Yue Jiang (Tissue Engineering and Regenerative Medicine, 2021)

Paraburkholderia sp. GD17 improves rice seedling tolerance to salinity - Ruanming Zhu; Yuting Cao; Guangzhe Li; Ying Guo; Lianju Ma; Ning Bu; Lin Hao (Plant and Soil, 2021)

Alfalfa (Medicago sativa L.) MsCML46 gene encoding calmodulin-like protein confers tolerance to abiotic stress in tobacco - Binghao Du; Naiyu Chen; Lili Song; Dan Wang; Hongsheng Cai; Lin Yao; Xiuting Li; Changhong Guo (Plant Cell Reports, 2021)

Depression Augments Plasma APOA4 without Changes of Plasma Lipids and Glucose in Female Adolescents Carrying G Allele of APOA4 rs5104 - Qi Wei Guo; Yan Jun Si; Yi Lin Shen; Xu Chen; Mei Yang; Ding Zhi Fang; Jia Lin (Journal of Molecular Neuroscience, 2021)

Anti-miR33 therapy improved hepatopancreatic lipid and immune metabolism disorders in grass carp, Ctenopharyngodon idella - Rong-Hua Lu; Meng-Jun Lin; Feng Yang; Shen-zong Jia; Yu-Ru Zhang; Chao-Bin Qin; Xiao-Lin Meng; Guo-Xing Nie (Fish Physiology and Biochemistry, 2021)

Shared and specific patterns of structural and functional thalamo-frontal disturbances in manic and euthymic pediatric bipolar disorder - Yi-Bing Guo; Wei-Jia Gao; Zhi-Liang Long; Wei-Fang Cao; Dong Cui; Yong-Xin Guo; Qing Jiao; Jian-Feng Qiu; Lin-Yan Su; Guang-Ming Lu (Brain Imaging and Behavior, 2021)
Bipolar disorder (BD) is clinically defined by alternating depressive and manic episodes with a separated period of euthymia. Thalamo-frontal loop plays vital role in psychotic symptoms, altered motor control and executive difficulties in BD. It remains unclear that structural and functional alterations of thalamo-frontal loop among the different mood states in BD, especially in pediatric BD(PBD). Twenty manic PBD (mPBD), 20 euthymic PBD (ePBD) and 19 healthy controls (HCs) were included in the study. By analyzing the T1 images and fMRI signals, thalamus volume and frontal grey matter cortical thickness were tested, and functional connectivity (FC) between bilateral thalamus and frontal cortex was calculated. Relationship between clinical indices and thalamo-frontal FC was also evaluated in mPBD and ePBD adolescents. Compared to HCs, the cortical thickness of left middle frontal gyrus (MFG), bilateral superior frontal gyrus (SFG) was significantly decreased in both mPBD and ePBD patients, and volume of left thalamus and cortical thickness of right MFG significantly decreased in mPBD patients. Compared to that of the HCs and ePBD subjects, thalamo-frontal hyperconnectivity with MFG was found in mPBD, and compared with that of HCs, thalamo-frontal hypoconnectivity with precentral gyrus/SFG was found in ePBD. In ePBD patients, episode times positively correlated with FC values between thalamus and precentral gyrus. The findings of the present study demonstrate detailed knowledge regarding shared and specific structural and functional disruption in thalamo-frontal loop in mPBD and ePBD subjects. Thalamo-frontal abnormalities reported in adult BD subjects were also observed in adolescent BD patients, and thalamo-frontal dysfunction may be a crucial treatment target in BD.

Irradiation-related longitudinal white matter atrophy underlies cognitive impairment in patients with nasopharyngeal carcinoma - Xiaoshan Lin; Linquan Tang; Mengjie Li; MingLi Wang; Zheng Guo; Xiaofei Lv; Yingwei Qiu (Brain Imaging and Behavior, 2021)

Ambient climate determines the directional trend of community stability under warming and grazing - Peipei Liu; Wangwang Lv; Jianping Sun; Caiyun Luo; Zhenhua Zhang; Xiaoxue Zhu; Xingwu Lin; Jichuang Duan; Guangping Xu; Xiaofeng Chang; Yigang Hu; Qiaoyan Lin; et al. (Global Change Biology, 2021)
Changes in ecological processes over time in ambient treatments are often larger than the responses to manipulative treatments in climate change experiments. However, the impacts of human‐driven environmental changes on the stability of natural grasslands have been typically assessed by comparing differences between manipulative plots and reference plots. Little is known about whether or how ambient climate regulates the effects of manipulative treatments and their underlying mechanisms. We collected two datasets, one a 36‐year long‐term observational dataset from 1983 to 2018, and the other a 10‐year manipulative asymmetric warming and grazing experiment using infrared heaters with moderate grazing from 2006 to 2015 in an alpine meadow on the Tibetan Plateau. The 36‐year observational dataset shows that there was a nonlinear response of community stability to ambient temperature with a positive relationship between them due to an increase in ambient temperature in the first 25 years and then a decrease in ambient temperature thereafter. Warming and grazing decreased community stability with experiment duration through an increase in legume cover and a decrease in species asynchrony, which was due to the decreasing background temperature through time during the 10‐year experiment period. Moreover, the temperature sensitivity of community stability was higher under the ambient treatment than under the manipulative treatments. Therefore, our results suggested that ambient climate may control the directional trend of community stability while manipulative treatments may determine the temperature sensitivity of the response of community stability to climate relative to the ambient treatment. Our study emphasizes the importance of the context dependency of the response of community stability to human‐driven environmental changes.

In silico design of antimicrobial oligopeptides based on 3D-QSAR modeling and bioassay evaluation - Guangping Li; Yuxuan Wang; Yan Shen; Haiqiong Guo; Qingxiu He; Yong Hu; Haibin Liu; Zhihua Lin; Yuanqiang Wang (Medicinal Chemistry Research, 2021)

Characterization of Yields, Osmotic Stress-associated Traits, and Expression Patterns of ABA Receptor Genes in Winter Wheat Under Deficit Irrigation - Xinyang Bai; Liguo Guo; Ruize Lin; Le Han; Kai Xiao (International Journal of Plant Production, 2021)

High-throughput sequencing clarifies the spatial structures of microbial communities in cadmium-polluted rice soils - Li Song; Zhenzhi Pan; Yi Dai; Lin Chen; Li Zhang; Qilin Liao; Xiezhi Yu; Hongyan Guo; Guisheng Zhou (Environmental Science and Pollution Research, 2021)

Acute associations between air pollution on premature rupture of membranes in Hefei, China - Chao Zhang; Sha Li; Gan-lan Guo; Jing-wen Hao; Peng Cheng; Li-lin Xiong; Shu-ting Chen; Ji-yu Cao; Yu-wen Guo; Jia-hu Hao (Environmental Geochemistry and Health, 2021)

Seasonal variation of flavonoid metabolites in leaves of Liquidambar formosana ‘Nanlinhong’ trees revealed by UPLC-ESI–MS/MS - Jiu-Xin Lai; Fu-Rong Lin; Ping Huang; Wen-Ying Guo; Lie-Bao Han; Yong-Qi Zheng (Brazilian Journal of Botany, 2021)

Application of the modified cytosine base-editing in the cultured cells of bama minipig - Jia-sheng Pan; Zi-sheng Lin; Jian-cong Wen; Jian-feng Guo; Xia-hui Wu; Ying-ying Liu; Wen-jun Lai; Qi-ying Liang; Yong-shi Xie; Yi-rou Chen; Yi-hong Chen; Ai-fen Yan; et al. (Biotechnology Letters, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

Estimation and Long-term Trend Analysis of Surface Solar Radiation in Antarctica: A Case Study of Zhongshan Station - Zhaoliang Zeng; Zemin Wang; Minghu Ding; Xiangdong Zheng; Xiaoyu Sun; Wei Zhu; Kongju Zhu; Jiachun An; Lin Zang; Jianping Guo; Baojun Zhang (Advances in Atmospheric Sciences, 2021)

A comparison of hepatotoxicity induced by different lengths of tungsten trioxide nanorods and the protective effects of melatonin in BALB/c mice - Lin Mao; Lifang Zheng; Huihui You; Muhammad Wajid Ullah; Haoyan Cheng; Qing Guo; Zhihong Zhu; Zhuge Xi; Rui Li (Environmental Science and Pollution Research, 2021)

Correction to: Gyral-sulcal contrast in intrinsic functional brain networks across task performances - Lin Zhao; Tuo Zhang; Lei Guo; Tianming Liu; Xi Jiang (Brain Imaging and Behavior, 2021)

Abnormal brain activity patterns during spatial working memory task in patients with end-stage renal disease on maintenance hemodialysis: a fMRI study - Jinzhuang Huang; Lei Xie; Ruiwei Guo; Jinhong Wang; Jinquan Lin; Zongbo Sun; Shouxing Duan; Zhirong Lin; Hui Li; Shuhua Ma (Brain Imaging and Behavior, 2021)
Hemodialysis (HD) is associated with cognitive impairment in patients with end-stage renal disease (ESRD). However, the neural mechanism of spatial working memory (SWM) impairment in HD-ESRD patients remains unclear. We investigated the abnormal alterations in SWM-associated brain activity patterns in HD-ESRD patients using blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) technique during n-back tasks. Twenty-two HD-ESRD patients and 22 well-matched controls underwent an fMRI scan while undergoing a three-load n-back tasks with different difficulty levels. Cognitive and mental states were assessed using a battery of neuropsychologic tests. The HD-ESRD patients exhibited worse memory abilities than controls. Compared with the control group, the HD-ESRD patient group showed lower accuracy and longer response time under the n-back tasks, especially in the 2-back task. The patterns of brain activation changed under different working memory loads in the HD-ESRD patients, showing decreased activity in the right medial frontal gyrus and inferior frontal gyrus under 0-back and 1-back task, while more decreased activation in the bilateral frontal cortex, parietal lobule, anterior/posterior cingulate cortex and insula cortex under 2-back task. With the increase of task difficulty, the activation degree of the frontal and parietal cortex decreased. More importantly, we found that lower activation in frontal cortex and parietal lobule was associated with worse cognitive function in the HD-ESRD patients. These results demonstrate that the abnormal brain activity patterns of frontal cortex and parietal lobule may reflect the neural mediation of SWM impairment.

Genetic changes and evolutionary analysis of canine circovirus - Lin Wang; Yifan li; Zhiyuan Guo; Ying Yi; Han Zhang; Haikun Shangguan; Chengshi Huang; Junwei Ge (Archives of Virology, 2021)

Dynamic changes in size‐fractionated dissolved organic matter composition in a seasonally ice‐covered Arctic River - Hui Lin; Huacheng Xu; Yihua Cai; Claude Belzile; Robie W. Macdonald; Laodong Guo (Limnology and Oceanography, 2021)
Arctic rivers are sensitive to climate and environmental change, but the biogeochemical response remains poorly understood. Monthly size‐fractionated dissolved organic matter (DOM) samples from the lower Yukon River were characterized using UV–visible, fluorescence, and Fourier transform‐infrared (FT‐IR) spectroscopy techniques. The EEM‐PARAFAC analysis revealed three major fluorescent DOM components, including two humic‐like components (C 480 and C 400 ) and one protein‐like component (C 310 ), with their relative importance following the order of C 480 ≥ C 400 > C 310 in the high‐molecular‐weight DOM (1 kDa–0.4 μ m) and C 400 > C 480 > C 310 in the low‐molecular‐weight DOM pool ( S 275–295 ) and specific UV absorbance at 254 nm (SUVA 254 ). These changes occurred within different DOM size‐fractions and among ice‐covered, spring freshet, and open seasons. Joint analysis of EEM and FT‐IR spectra using a data fusion technique showed that humic‐like DOM is mostly associated with C─H, C═C, and C─O bonds, while protein‐like DOM is correlated more with C─N and N─H related structures. DOM aromaticity and the ratios of HIX to BIX and protein‐like to humic‐like components may be used as a compelling proxy to measure change in source waters and to infer permafrost dynamics. Our results provide insight into the seasonal variation in DOM composition for different size‐fractions in the lower Yukon River, and a baseline dataset against which future changes can be understood in the context of arctic basin biogeochemical cycling.

Terpenoids from the South China Sea soft coral Sinularia multiflora - Zheng Wang; Ping-Lin Li; Xiang-Chao Luo; Qi Wang; Leen van Ofwegen; Xu-Li Tang; Guo-Qiang Li (Natural Product Research, 2021)

Vertical structure of Tibetan Plateau Vortex in boreal summer - Zhiqiang Lin; Xiuping Yao; Weidong Guo; Jun Du (Theoretical and Applied Climatology, 2021)

Identification of a delayed leaf greening gene from a mutation of pummelo - Hui-Wen Yu; Zhi-Hao Lu; Xia Wang; Dan Liu; Jia-Xian He; Xiao-Lin Jiang; Ling-Jun Ke; Wen-Wu Guo; Xiu-Xin Deng; Qiang Xu (Science China Life Sciences, 2021)

Comparative analysis of sRNAs, degradome and transcriptomics in sweet sorghum reveals the regulatory roles of miRNAs in Cd accumulation and tolerance - Weitao Jia; Kangqi Lin; Tengxue Lou; Juanjuan Feng; Sulian Lv; Ping Jiang; Ze Yi; Xuan Zhang; Duoliya Wang; Zijing Guo; Yetao Tang; Rongliang Qiu; et al. (Planta, 2021)

Empathy-based tolerance towards poor norm violators in third-party punishment - Hui Ouyang; Jingqian Yu; Jipeng Duan; Li Zheng; Lin Li; Xiuyan Guo (Experimental Brain Research, 2021)

Do air pollutants as well as meteorological factors impact Corona Virus Disease 2019 (COVID-19)? Evidence from China based on the geographical perspective - Lin Pei; Xiaoxia Wang; Bin Guo; Hongjun Guo; Yan Yu (Environmental Science and Pollution Research, 2021)

A massive ancient river-damming landslide triggered by buckling failure in the upper Jinsha River, SE Tibetan Plateau - Yanyan Li; Xuyang Feng; Aijun Yao; Shan Lin; Rui Wang; Mingzhu Guo (Bulletin of Engineering Geology and the Environment, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

Detection of Vestibular Schwannoma on Triple-parametric Magnetic Resonance Images Using Convolutional Neural Networks - Tzu-Hsuan Huang; Wei-Kai Lee; Chih-Chun Wu; Cheng-Chia Lee; Chia-Feng Lu; Huai-Che Yang; Chun-Yi Lin; Wen-Yuh Chung; Po-Shan Wang; Yen-Ling Chen; Hsiu-Mei Wu; Wan-You Guo; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose The first step in typical treatment of vestibular schwannoma (VS) is to localize the tumor region, which is time-consuming and subjective because it relies on repeatedly reviewing different parametric magnetic resonance (MR) images. A reliable, automatic VS detection method can streamline the process. Methods A convolutional neural network architecture, namely YOLO-v2 with a residual network as a backbone, was used to detect VS tumors from MR images. To heighten performance, T1-weighted–contrast-enhanced, T2-weighted, and T1-weighted images were combined into triple-channel images for feature learning. The triple-channel images were cropped into three sizes to serve as input images of YOLO-v2. The VS detection effectiveness levels were evaluated for two backbone residual networks that downsampled the inputs by 16 and 32. Results The results demonstrated the VS detection capability of YOLO-v2 with a residual network as a backbone model. The average precision was 0.7953 for a model with 416 × 416-pixel input images and 16 instances of downsampling, when both the thresholds of confidence score and intersection-over-union were set to 0.5. In addition, under an appropriate threshold of confidence score, a high average precision, namely 0.8171, was attained by using a model with 448 × 448-pixel input images and 16 instances of downsampling. Conclusion We demonstrated successful VS tumor detection by using a YOLO-v2 with a residual network as a backbone model on resized triple-parametric MR images. The results indicated the influence of image size, downsampling strategy, and confidence score threshold on VS tumor detection.

Secondary Structural Transformation of Bovine Lactoferricin Affects Its Antibacterial Activity - Jie Pei; Lin Xiong; Pengjia Bao; Min Chu; Ping Yan; Xian Guo (Probiotics and Antimicrobial Proteins, 2021)

Late Jurassic Maofengshan two‐mica granites in Guangzhou, South China: fractional crystallization products of metasedimentary‐rock‐derived magmas - Xiao Liu; Qiang Wang; Lin Ma; Guo-Ning Gou; Quan Ou; Jun Wang (Mineralogy and Petrology, 2021)

Soil fertility, enzyme activity, and microbial community structure diversity among different soil textures under different land use types in coastal saline soil - Yun Zhu; Bin Guo; Chen Liu; Yicheng Lin; Qinglin Fu; Ningyu Li; Hua Li (Journal of Soils and Sediments, 2021)

Seed blends of pyramided Cry/Vip maize reduce Helicoverpa zea populations from refuge ears - Jianguo Guo; Isaac Oyediran; Marlin E. Rice; Sebe Brown; Marcelo Dimase; Shucong Lin; Wade Walker; Wenbo Yu; Ying Niu; Fangneng Huang (Journal of Pest Science, 2021)

Five matrine-type alkaloids from Sophora tonkinensis - Qing Tang; Ding Luo; Ding-Chai Lin; Wen-Zhi Wang; Can-Jie Li; Xue-Fang Zhuo; Zhong-Nan Wu; Yu-Bo Zhang; Guo-Cai Wang; Yao-Lan Li (Journal of Natural Medicines, 2021)

Alterinioella nitratireducens gen. nov., sp. nov., Isolated from Seawater in the West Pacific Ocean - Yan-Hui Kong; Cong Sun; Li-Li Guo; Lin Xu; Yue-Hong Wu; Xue-Wei Xu (Current Microbiology, 2021)

Gyral-sulcal contrast in intrinsic functional brain networks across task performances - Lin Zhao; Tuo Zhang; Lei Guo; Tianming Liu; Xi Jiang (Brain Imaging and Behavior, 2021)

Modelling plant canopy effects on water-heat exchange in the freezing-thawing processes of active layer on the Qinghai-Tibet Plateau - Lin-mao Guo; Juan Chang; Hong-liang Xu; Wen-jun Sun (Journal of Mountain Science, 2021)

PI3K/Akt/mTOR Signaling as Targets for Developing Anticancer Agents from Marine Organisms - Mingyue Guo; Ling Zuo; Gan Qiao; Minghua Liu; Shousong Cao; Xiukun Lin (Journal of Ocean University of China, 2021)

Quantitative characterization of horizontal well production performance with multiple indicators: a case study on the Weiyuan shale gas field in the Sichuan Basin, China - Rongze Yu; Wei Guo; Lin Ding; Meizhu Wang; Feng Cheng; Xiaowei Zhang; Shangwen Zhou; Leifu Zhang (Frontiers of Earth Science, 2021)

A quantitative study of the scale and distribution of tight gas reservoirs in the Sulige gas field, Ordos Basin, northwest China - Chao Luo; Ailin Jia; Jianlin Guo; Qing Tian; Junlei Wang; Hun Lin; Nanxin Yin; Xuanbo Gao (Frontiers of Earth Science, 2021)

Amygdala-based Functional Network Reveals Dissociated Neural Correlates of Consensual and Idiosyncratic Emotional Movie Experiences - Lin Cui; Bingbing Guo; Dan Zhao; Jiaxin Li; Yu Luo; Ming Meng (Neuroscience Bulletin, 2021)

New insights into the fine-scale history of western–eastern admixture of the northwestern Chinese population in the Hexi Corridor via genome-wide genetic legacy - Hongbin Yao; Mengge Wang; Xing Zou; Yingxiang Li; Xiaomin Yang; Ailin Li; Hui-Yuan Yeh; Peixin Wang; Zheng Wang; Jingya Bai; Jianxin Guo; Jinwen Chen; et al. (Molecular Genetics and Genomics, 2021)

Stoichiometric relations of C, N, and P in urban top soils in Nanjing, China, and their biogeochemical implications - Jin-Ling Yang; Da-Gang Yuan; Yu-Guo Zhao; Yue He; Gan-Lin Zhang (Journal of Soils and Sediments, 2021)

Genome-wide identification and expression analysis of the MADS-box transcription factor family in Camellia sinensis - Zai-Bao Zhang; Yuan-Jin Jin; Hou-Hong Wan; Lin Cheng; Zhi-Guo Feng (Journal of Applied Genetics, 2021)

Pharmaceuticals and personal care products in the seawater around a typical subtropical tourist city of China and associated ecological risk - Hongzhe Chen; Wenfeng Chen; Huige Guo; Hui Lin; Yuanbiao Zhang (Environmental Science and Pollution Research, 2021)

Exposed to Mercury-Induced Oxidative Stress, Changes of Intestinal Microflora, and Association between them in Mice - Yulan Zhao; Changming Zhou; Xiaoquan Guo; Guoliang Hu; Guyue Li; Yu Zhuang; Huabin Cao; Lin Li; Chonghong Xing; Caiying Zhang; Fan Yang; Ping Liu (Biological Trace Element Research, 2021)

Cryostructures and ground ice content in ice-rich permafrost area of the Qinghai-Tibet Plateau with Computed Tomography Scanning - Xing-wen Fan; Zhan-ju Lin; Ze-yong Gao; Xiang-lian Meng; Fu-jun Niu; Jing Luo; Guo-an Yin; Fu-jun Zhou; Ai-yu Lan (Journal of Mountain Science, 2021)

Microbial transformation of distinct exogenous substrates into analogous composition of recalcitrant dissolved organic matter - Jie Lian; Xiaoxuan Zheng; Xiaocun Zhuo; Yi‐Lung Chen; Chen He; Qiang Zheng; Ta‐Hui Lin; Jia Sun; Weidong Guo; Quan Shi; Nianzhi Jiao; Ruanhong Cai (Environmental Microbiology, 2021)
Summary Oceanic dissolved organic matter (DOM) comprises a complex molecular mixture which is typically refractory and homogenous in the deep layers of the ocean. Though the refractory nature of deep‐sea DOM is increasingly attributed to microbial metabolism, it remains unexplored whether ubiquitous microbial metabolism of distinct carbon substrates could lead to similar molecular composition of refractory DOM. Here, we conducted microbial incubation experiments using four typically bioavailable substrates (L‐alanine, trehalose, sediment DOM extract, and diatom lysate) to investigate how exogenous substrates are transformed by a natural microbial assemblage. The results showed that although each‐substrate‐amendment induced different changes in the initial microbial assemblage and the amended substrates were almost depleted after 90 days of dark incubation, the bacterial community compositions became similar in all incubations on day 90. Correspondingly, revealed by ultra‐high resolution mass spectrometry, molecular composition of DOM in all incubations became compositionally consistent with recalcitrant DOM and similar toward that of DOM from the deep‐sea. These results indicate that while the composition of natural microbial communities can shift with substrate exposures, long‐term microbial transformation of distinct substrates can ultimately lead to a similar refractory DOM composition. These findings provide an explanation for the homogeneous and refractory features of deep‐sea DOM.

Mortality burden caused by diurnal temperature range: a nationwide time-series study in 364 Chinese locations - Min Cai; Jianxiong Hu; Chunliang Zhou; Zhulin Hou; Yanjun Xu; Maigeng Zhou; Yize Xiao; Biao Huang; Xiaojun Xu; Lifeng Lin; Tao Liu; Jianpeng Xiao; et al. (Stochastic Environmental Research and Risk Assessment, 2021)

Triaxial Compression Testing at Constant and Reducing Confining Pressure for the Mechanical Characterization of a Specific Type of Sandstone - Jiu-chang Zhang; Zhi-nan Lin; Bo Dong; Rong-xin Guo (Rock Mechanics and Rock Engineering, 2021)

TLR8 in the Trigeminal Ganglion Contributes to the Maintenance of Trigeminal Neuropathic Pain in Mice - Lin-Xia Zhao; Ming Jiang; Xue-Qiang Bai; De-Li Cao; Xiao-Bo Wu; Jing Zhang; Jian-Shuang Guo; Tong-Tong Chen; Juan Wang; Hao Wu; Yong-Jing Gao; Zhi-Jun Zhang (Neuroscience Bulletin, 2021)
Trigeminal neuropathic pain (TNP) is a significant health problem but the involved mechanism has not been completely elucidated. Toll-like receptors (TLRs) have recently been demonstrated to be expressed in the dorsal root ganglion and involved in chronic pain. Here, we show that TLR8 was persistently increased in the trigeminal ganglion (TG) neurons in model of TNP induced by partial infraorbital nerve ligation (pIONL). In addition, deletion or knockdown of Tlr8 in the TG attenuated pIONL-induced mechanical allodynia, reduced the activation of ERK and p38-MAPK, and decreased the expression of pro-inflammatory cytokines in the TG. Furthermore, intra-TG injection of the TLR8 agonist VTX-2337 induced pain hypersensitivity. VTX-2337 also increased the intracellular Ca 2+ concentration, induced the activation of ERK and p38, and increased the expression of pro-inflammatory cytokines in the TG. These data indicate that TLR8 contributes to the maintenance of TNP through increasing MAPK-mediated neuroinflammation. Targeting TLR8 signaling may be effective for the treatment of TNP.

Phylogeny and taxonomy of two new Alternaria (Ascomycota: Pleosporaceae) species in section Gypsophilae from China - Lin He; Hong Cheng; Aye Aye Htun; Hui Ge; Zhen Zhou Xia; Jian Wei Guo; Jian Xin Deng; Tao Du (Mycological Progress, 2021)

The effect of cyfluthrin on testis inhibin B in rats and the intervention of Lycium barbarum polysaccharide - Xin Guo; Yong-Xin Xie; Chen Guo; Jing-Lin Wei; Hui-Fang Yang (Molecular & Cellular Toxicology, 2021)

Crenobacter intestini sp. nov., Isolated from the Intestinal Tract of Konosirus punctatus - Song-Biao Shi; Jia-Fa Wu; Li-Fang Yang; Ming-Guo Jiang; Cai-Mi Gao; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Experimental and numerical study on the fragmentation mechanism of a single calcareous sand particle under normal compression - Du-min Kuang; Zhi-lin Long; Rui-qi Guo; Tao Zhao; Kai Wu (Bulletin of Engineering Geology and the Environment, 2021)

Genome-Wide Identification of Copper Stress-Regulated and Novel MicroRNAs in Mulberry Leaf - Qiuxia Du; Peng Guo; Yisu Shi; Jian Zhang; Danyan Zheng; Yang Li; Adolf Acheampong; Ping Wu; Qiang Lin; Weiguo Zhao (Biochemical Genetics, 2021)

Adaptive Evolution of Chalcone Isomerase Superfamily in Fagaceae - Li-Mei Lin; Hong-Yu Guo; Xin Song; Duo-Duo Zhang; Yue-Hong Long; Zhao-Bin Xing (Biochemical Genetics, 2021)

The molecular mechanism of a novel derivative of BTO-956 induced apoptosis in human myelomonocytic lymphoma cells - Yu-Lin Li; De-Jun Zhou; Zheng-Guo Cui; Lu Sun; Qian-Wen Feng; Shahbaz Ahmad Zakki; Yusuke Hiraku; Cheng-Ai Wu; Hidekuni Inadera (Apoptosis, 2021)

A shallow artificial neural network for mapping bond strength of soil nails - Huifen Liu; Peiyuan Lin; Chengchao Guo; Zhongbao Li; Xiao Qin (Marine Georesources & Geotechnology, 2021)

Landslide hazard assessment of rainfall-induced landslide based on the CF-SINMAP model: a case study from Wuling Mountain in Hunan Province, China - Wei Lin; Kunlong Yin; Ningtao Wang; Yong Xu; Zizheng Guo; Yuanyao Li (Natural Hazards, 2021)

Dysfunction of chaperone-mediated autophagy in human diseases - Zhaozhong Liao; Bin Wang; Wenjing Liu; Qian Xu; Lin Hou; Jinlian Song; Qingming Guo; Ning Li (Molecular and Cellular Biochemistry, 2021)

Upregulation of long noncoding RNA XIST has anticancer effects on ovarian cancer through sponging miR-106a - Ting Guo; Donglan Yuan; Wei Zhang; Dandan Zhu; Aifang Xiao; Guangyao Mao; Wenjuan Jiang; Mei Lin; Jun Wang (Human Cell, 2021)

Transcriptome profiling reveals candidate genes associated with cold stress in mulberry - Acheampong Adolf; Li Liu; Michael Ackah; Yang Li; Qiuxia Du; Danyan Zheng; Peng Guo; Yisu Shi; Qiang Lin; Changyu Qiu; Weiguo Zhao (Brazilian Journal of Botany, 2021)

Identification of Aspergillus tubingensis causing pomegranate fruit rot in China - Mei Jun Guo; Qiu Tong Wang; Yuan Hui Cheng; Cheng Lin Hou (Australasian Plant Pathology, 2021)

Complete genome sequence of a novel foveavirus isolated from Allium sativum L. in China - Qi Luo; Shuzhen Hu; Qi Lin; Fei Xu; Jiejun Peng; Hongying Zheng; Guanwei Wu; Shaofei Rao; Jianping Chen; Yuwen Lu; Fengling Guo; Fei Yan (Archives of Virology, 2021)

Evaluation of reanalysis surface wind products with quality-assured buoy wind measurements along the north coast of the South China Sea - Jing Cha; Xinyu Lin; Xiaogang Guo; Xiaofang Wan; Dawei You (Acta Oceanologica Sinica, 2021)

Seasonal variations in the water residence time in the Bohai Sea using 3D hydrodynamic model study and the adjoint method - Chongxin Luo; Lei Lin; Jie Shi; Zhe Liu; Zhongya Cai; Xinyu Guo; Huiwang Gao (Ocean Dynamics, 2021)

TMEM166 inhibits cell proliferation, migration and invasion in hepatocellular carcinoma via upregulating TP53 - Jiejie Yang; Bin Wang; Qian Xu; Yuling Yang; Lin Hou; Kan Yin; Qingming Guo; Yanan Hua; Li Zhang; Yixuan Li; Jinyu Zhang; Ning Li (Molecular and Cellular Biochemistry, 2021)

Gastrointestinal toxicities associated with immune checkpoint inhibitors: a disproportionality analysis leveraging VigiBase, the WHO Adverse Drug Reaction Database - Sifu Huang; Xuefeng Bai; Taiyong Fang; Yanta Guo; Kainan Zheng; Xiahong Lin (Journal of Zhejiang University-SCIENCE B, 2021)

Gentianella acuta prevents acute myocardial infarction induced by isoproterenol in rats via inhibition of galectin-3/TLR4/MyD88/NF-кB inflammatory signalling - Jia-Huan Sun; Hong-Xia Yang; Ting-Ting Yao; Yuan Li; Lin Ruan; Geng-Rui Xu; Chuang Zhang; Guo-Xin Guo; Ai-Ying Li (Inflammopharmacology, 2021)

Genotyping-by-sequencing to determine the genetic structure of a Tibetan medicinal plant Swertia mussotii Franch. - Yan Qiao; Fengxian Guo; Naxin Huo; Lin Zhan; Jiaqing Sun; Xixi Zuo; Zeguang Guo; Yong Q. Gu; Yi Wang; Yue Liu (Genetic Resources and Crop Evolution, 2021)

Association between particulate matter air pollution and risk of depression and suicide: a systematic review and meta-analysis - Qisijing Liu; Wanzhou Wang; Xuelin Gu; Furong Deng; Xueqin Wang; Hualiang Lin; Xinbiao Guo; Shaowei Wu (Environmental Science and Pollution Research, 2021)

18 Additional Amino Acids of the Signal Peptide of the Bombyx mori Nucleopolyhedrovirus GP64 Activates Immunoglobulin Binding Protein (BiP) Expression by RNA-seq Analysis - Na Liu; Jinshan Huang; Lin Liu; Frank Boadi; Yanhui Song; Zhongjian Guo; Xingjia Shen; Bifang Hao (Current Microbiology, 2021)

Datasets for the CMIP6 Scenario Model Intercomparison Project (ScenarioMIP) Simulations with the Coupled Model CAS FGOALS-f3-L - Shuwen Zhao; Yongqiang Yu; Pengfei Lin; Hailong Liu; Bian He; Qing Bao; Yuyang Guo; Lijuan Hua; Kangjun Chen; Xiaowei Wang (Advances in Atmospheric Sciences, 2021)
The datasets for the tier-1 Scenario Model Intercomparison Project (ScenarioMIP) experiments from the Chinese Academy of Sciences (CAS) Flexible Global Ocean-Atmosphere-Land System model, finite-volume version 3 (CAS FGOALS-f3-L) are described in this study. ScenarioMIP is one of the core MIP experiments in phase 6 of the Coupled Model Intercomparison Project (CMIP6). Considering future CO 2 , CH 4 , N 2 O and other gases’ concentrations, as well as land use, the design of ScenarioMIP involves eight pathways, including two tiers (tier-1 and tier-2) of priority. Tier-1 includes four combined Shared Socioeconomic Pathways (SSPs) with radiative forcing, i.e., SSP1-2.6, SSP2-4.5, SSP3-7.0 and SSP5-8.5, in which the globally averaged radiative forcing at the top of the atmosphere around the year 2100 is approximately 2.6, 4.5, 7.0 and 8.5 W m −2 , respectively. This study provides an introduction to the ScenarioMIP datasets of this model, such as their storage location, sizes, variables, etc. Preliminary analysis indicates that surface air temperatures will increase by about 1.89°C, 3.07°C, 4.06°C and 5.17°C by around 2100 under these four scenarios, respectively. Meanwhile, some other key climate variables, such as sea-ice extension, precipitation, heat content, and sea level rise, also show significant long-term trends associated with the radiative forcing increases. These datasets will help us understand how the climate will change under different anthropogenic and radiative forcings.

Highly enriched N‐containing organic molecules of Synechococcus lysates and their rapid transformation by heterotrophic bacteria - Qiang Zheng; Wenxin Lin; Yu Wang; Yunyun Li; Chen He; Yuan Shen; Weidong Guo; Quan Shi; Nianzhi Jiao (Limnology and Oceanography, 2021)
Phytoplankton are major contributors of labile dissolved organic matter to marine euphotic zone ecosystems. Viral‐mediated phytoplankton lysis releases a considerable amount of bioavailable cellular contents and facilitates localized heterotrophic bacterial growth. The rapid turnover times of this labile organic matter renders it difficult to trace their transformation within natural environments. In the present study, we used a model phototroph‐heterotroph coculture system to investigate the organic molecular variation during cyanophage‐induced Synechococcus lysis and post‐lysis periods using fluorescence spectroscopy and ultrahigh resolution mass spectrometry analyses. Approximately 80% of the Synechococcus lysates were respired to carbon dioxide within 2 days coupled to rapid regeneration of inorganic nutrients. Five fluorescent dissolved organic matter components were detected in the incubations including four humic‐like and one protein‐like components, and their abundances varied markedly with the succession of the viral lysis process. Viral lysis promoted the transformation of Synechococcus biomass to dissolved organic matter, and heterotrophic bacterial metabolism facilitated the transformation of organic molecules from relatively high (avg. ~ 430 Da) to low (avg. ~ 360 Da) molecular weight, corresponding to variation in their bioavailability. The Synechococcus ‐derived organic matter was highly enriched in N‐containing organic molecules. Identified metabolites within the cultures primarily comprised amino acids or oligopeptides and other low‐molecular‐weight organic acids, carbohydrates, nucleotides, lipids, biogenic amines, and porphyrins. Among these, oligopeptides, nucleotides, and lipid compounds significantly increased with viral lysis. These results provide insight into biogeochemical cycling mediated by viral shunts in oceans, thus deepening our understanding of microbial food webs at the molecular level.

Community structure of bacterioplankton and its relationship with environmental factors in the upper reaches of the Heihe River in Qinghai Plateau - Zhang Qian‐Qian; Jian Sheng‐Long; Li Ke‐Mao; Wu Zhen‐Bing; Guan Hong‐Tao; Hao Jin‐Wen; Wang Shu‐Yi; Lin Yao‐Yao; Wang Guo‐Jie; Li Ai‐Hua (Environmental Microbiology, 2021)
Summary Planktonic microorganisms play a key role in the biogeochemical processes of the aquatic system, and they may be affected by many factors. High‐throughput sequencing technology was used in this study to investigate and study the bacterioplankton community of water bodies in the upper reaches of the Heihe River Basin in Qinghai Plateau. Results showed that Proteobacteria, Firmicutes, Bacteroidetes and Actinobacteria are the predominant phyla in this river section, while the main genera are Thiomonas , Acidibacillus , Acidocella , Rhodanobacter , Acidithiobacter and Gallionella , which are autochthonous in the acid‐mine drainage. Additionally, total nitrogen, total phosphorus, permanganate index and pH are significantly correlated with the bacterioplankton abundance and are the main limiting factors for the spatial distribution of the bacterioplankton. PICRUSt inferred that the mainstream microbial assemblages had a higher abundance of KOs belong to metabolism of terpenoids and polyketides, while the tributary had higher abundance of KOs belong to the immune system. The relationship between bacterioplankton community composition and environmental factors in the Heihe River basin was discussed for the first time in this study, which provides a theoretical basis for the healthy, orderly development of the water environment in the Heihe River Basin.

Study on the Rheological Behavior of a Model Clay Sediment - Yuan Lin; Huaitao Qin; Jin Guo; Jiawang Chen (Journal of Marine Science and Engineering, 2021)
Clay sediments are the main component of seabed sediment. Interactions between the nano-sized, disk-shaped and charged clay particles are complicated, as they control the sediment’s rheology. In this study, we studied the rheological behavior of the clay sediment modeled by laponite and bentonite suspensions experimentally using a rotational rheometer. The yield stress decreased when water content increased. Meanwhile, the yield stress of the laponite suspension first increased and then decreased with increasing salinity. It is considered that the face-to-face repulsive electrostatic interaction between clay platelets dominated the yield behavior. A yield stress model was developed to describe the change of the yield stress with both the water content and the salinity. When the system started to flow, the viscosity decreased with increasing shear. A master curve of viscosity is was from the viscosity-stress curves at different water contents if the applied shear stress was normalized by the yield stress and the viscosity normalized by a characteristic viscosity. This study provides a preliminary understanding of the clay sediment rheology and its mechanism for the investigation on the flowing of the sediment systems with strong interparticle interaction.

Chronic Oral Administration of Magnesium-L-Threonate Prevents Oxaliplatin-Induced Memory and Emotional Deficits by Normalization of TNF-α/NF-κB Signaling in Rats - Xin Zhou; Zhuo Huang; Jun Zhang; Jia-Liang Chen; Pei-Wen Yao; Chun-Lin Mai; Jie-Zhen Mai; Hui Zhang; Xian-Guo Liu (Neuroscience Bulletin, 2021)

Biochar improves heavy metal passivation during wet anaerobic digestion of pig manure - Jun Wang; Xiaoxia Hao; Zile Liu; Zili Guo; Li Zhu; Bangjie Xiong; Dongmei Jiang; Linyuan Shen; Mingzhou Li; Bo Kang; Guoqing Tang; Lin Bai (Environmental Science and Pollution Research, 2021)

Development of redox potential-driven fermentation process for recombinant protein expression - Jingjie Guo; Yixuan Wu; Takuji Tanaka; Yen-Han Lin (Biotechnology Letters, 2021)

A DEM fusion method for ascending and descending orbit StereoSAR DEMs in complicated mountain areas considering SAR echo intensity - Guo-lin Cai; Dong Shen; Ao-li Zhang; Hai-hua Yu; Xuan-yu Zhang (Journal of Mountain Science, 2021)

Multifractal characteristics and spatial variability of soil particle-size distribution in different land use patterns in a small catchment of the Three Gorges Reservoir Region, China - Tai-li Chen; Zhong-lin Shi; An-bang Wen; Dong-chun Yan; Jin Guo; Jia-cun Chen; Yuan Liu; Rui-yin Chen (Journal of Mountain Science, 2021)

Analysis of fracturing characteristics of unconfined rock plate under edge-on impact loading - Yixian Wang; Hang Lin; Yanlin Zhao; Xian Li; Panpan Guo; Yan Liu (European Journal of Environmental and Civil Engineering, 2020)

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Wetland Ecosystem Service Dynamics in the Yellow River Estuary under Natural and Anthropogenic Stress in the Past 35 Years - Huijuan Xia; Lusan Liu; Junhong Bai; Weijing Kong; Kuixuan Lin; Fen Guo (Wetlands, 2020)

The Application of Decellularized Adipose Tissue Promotes Wound Healing - Zenan Xia; Xiao Guo; Nanze Yu; Ang Zeng; Loubin Si; Fei Long; Wenchao Zhang; Xiaojun Wang; Lin Zhu; Zhifei Liu (Tissue Engineering and Regenerative Medicine, 2020)

Quantitative Determination of Glymphatic Flow Using Spectrophotofluorometry - Yu Zhang; Jian Song; Xu-Zhong He; Jian Xiong; Rong Xue; Jia-Hao Ge; Shi-Yu Lu; Die Hu; Guo-Xing Zhang; Guang-Yin Xu; Lin-Hui Wang (Neuroscience Bulletin, 2020)

Weathering the storm: COVID-19 infection in patients with hematological malignancies - Lin-qin Wang; Elaine Tan Su Yin; Guo-qing Wei; Yong-xian Hu; Arnon Nagler; He Huang (Journal of Zhejiang University-SCIENCE B, 2020)

Culturally Tailored Intervention to Promote Mammography Screening Practice Among Chinese American Women: a Systematic Review - Xuehui Zhang; Ping Li; Pingping Guo; Jie Wang; Na Liu; Shu Yang; Lin Yu; Xiumin Zhang; Wei Zhang (Journal of Cancer Education, 2020)

Evaluations of the serological test in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak - Dachuan Lin; Lei Liu; Mingxia Zhang; Yunlong Hu; Qianting Yang; Jiubiao Guo; Youchao Dai; Yuzhong Xu; Yi Cai; Xinchun Chen; Kaisong Huang; Zheng Zhang (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

An allotriploid hybrid developed from a female 2n gamete was obtained from Eriobotrya japonica (Thunb.) Lindl × E. deflexa (Hemsl.) Nakai - Yanjuan Song; Jiangbo Dang; Weiwei Chen; Guo Wen; Qiao He; Xiaolin Li; Shoukai Lin; Guolu Liang; Qigao Guo (Euphytica, 2020)

Cortical 3-hinges could serve as hubs in cortico-cortical connective network - Tuo Zhang; Xiao Li; Xi Jiang; Fangfei Ge; Shu Zhang; Lin Zhao; Huan Liu; Ying Huang; Xianqiao Wang; Jian Yang; Lei Guo; Xiaoping Hu; et al. (Brain Imaging and Behavior, 2020)
Mapping the relation between cortical convolution and structural/functional brain architectures could provide deep insights into the mechanisms of brain development, evolution and diseases. In our previous studies, we found a unique gyral folding pattern, termed a 3-hinge, which was defined as the conjunction of three gyral crests. The uniqueness of the 3-hinge was evidenced by its thicker cortex and stronger fiber connections than other gyral regions. However, the role that 3-hinges play in cortico-cortical connective architecture remains unclear. To this end, we conducted MRI studies by constructing structural cortico-cortical connective networks based on a fine-granular cortical parcellation, the parcels of which were automatically labeled as 3-hinge, 2-hinge (ordinary gyrus) or sulcus. On human brains, 3-hinges possess significantly higher degrees, strengths and betweennesses than 2-hinges, suggesting that 3-hinges could serve more like hubs in the cortico-cortical connective network. This hypothesis gains supports from human functional network analyses, in which 3-hinges are involved in more global functional networks than ordinary gyri. In addition, 3-hinges could serve as ‘connector’ hubs rather than ‘provincial’ hubs and they account for a dominant proportion of nodes in the high-level ‘backbone’ of the network. These structural results are reproduced on chimpanzee and macaque brains, while the roles of 3-hinges as hubs become more pronounced in higher order primates. Our new findings could provide a new window to the relation between cortical convolution, anatomical connection and brain function.

Production of gene-edited pigs harboring orthologous human mutations via double cutting by CRISPR/Cas9 with long single-stranded DNAs as homology-directed repair templates by zygote injection - Fei Xie; Xiaoyang Zhou; Tingting Lin; Lulu Wang; Chuanhong Liu; Xi Luo; Lihua Luo; Huayu Chen; Kenan Guo; Hong Wei; Yong Wang (Transgenic Research, 2020)

Numerical and Experimental Study of Flow Field between the Main Hull and Demi-Hull of a Trimaran - Cong Sun; Chunyu Guo; Chao Wang; Lianzhou Wang; Jianfeng Lin (Journal of Marine Science and Engineering, 2020)
The interactions between the main hull and demi-hull of trimarans have been arousing increasing attention, and detailed circumferential flow fields greatly influence trimaran research. In this research, the unsteady wake flow field of a trimaran was obtained by Reynolds-Averaged Navier-Stokes (RANS) equations on the basis of the viscous flow principles with consideration of the heaving and pitching of the trimaran. Then, we designed an experimental method based on particle-image velocimetry (PIV) and obtained a detailed flow field between the main hull and demi-hull of the trimaran. A trimaran model with one demi-hull made of polycarbonate material with 90% light transmission rate and a refractive index 1.58 (close to that of water 1.33) was manufactured as the experiment sample. Using polycarbonate material, the laser-sheet light-source transmission and high-speed camera recording problems were effectively rectified. Moreover, a nonstandard calibration was added into the PIV flow field measurement system. Then, we established an inverse three-dimensional (3D) distortion coordinate system and obtained the corresponding coordinates by using optics calculations. Further, the PIV system spatial mapping was corrected, and the real flow field was obtained. The simulation results were highly consistent with the experimental data, which showed the methods established in this study provided a strong reference for obtaining the detailed flow field information between the main hull and demi-hull of trimarans.

Geochemical constraints on the origin of late Cenozoic basalts in the Mt. Changbai volcanic field, NE China: evidence for crustal recycling - Ming Lei; Zhengfu Guo; Yutao Sun; Maoliang Zhang; Lihong Zhang; Lin Ma (International Geology Review, 2020)

Two new sesquiterpenoid glycosides from the stems of Zanthoxylum armatum DC - Ya-Lin Liu; Liang-Liang Gao; Tong-Tong Song; Tao Guo; Jun Chang (Natural Product Research, 2020)

Small grain and semi-dwarf 3, a WRKY transcription factor, negatively regulates plant height and grain size by stabilizing SLR1 expression in rice - Jie Lan; Qibing Lin; Chunlei Zhou; Yakun Ren; Xi Liu; Rong Miao; Ruonan Jing; Changling Mou; Thanhliem Nguyen; Xingjie Zhu; Qian Wang; Xin Zhang; et al. (Plant Molecular Biology, 2020)

A Comparative Study of Associated Microbiota Between Pig Farm and Pig Slaughterhouse in Guangdong, China - Jian-Yong Wu; Yan-Shan Zhu; Cheng Guo; Yao Xia; Zhong-Min Guo; Qian-Lin Li; Jia-Hai Lu (Current Microbiology, 2020)

Ovarian development pattern and vitellogenesis of ridgetail white prawn, Exopalaemon carinicauda - Lin Wang; Qing Guo; Tom Levy; Ting Chen; Xugan Wu (Cell and Tissue Research, 2020)

Nitrogen‐induced acidification, not N‐nutrient, dominates suppressive N effects on arbuscular mycorrhizal fungi - Shang Pan; Yang Wang; Yunpeng Qiu; Dima Chen; Lin Zhang; Chenglong Ye; Hui Guo; Weixing Zhu; Aiqun Chen; Guohua Xu; Yi Zhang; Yongfei Bai; et al. (Global Change Biology, 2020)
Arbuscular mycorrhizal fungi (AMF) form symbiosis with most terrestrial plant roots, obtaining photosynthates in return for mineral nutrients. Ecological theories based on the economics of trading partnership predict that nutrient enrichment would suppress AMF. Experimental results from nitrogen (N) and phosphorus (P) additions, however, were highly variable, and the underlying mechanisms remain unclear. Here we show distinct AMF responses to soil N:P stoichiometry manipulations via gradients of long‐term N and P additions in a Mongolian steppe. A complementary experiment with an acid addition gradient was designed to help tease apart the effect of N‐induced acidification from N nutrient. AMF root colonization and extraradical fungal biomass progressively decreased along the P gradient under two distinct host plant species, suggesting a carbon (C)‐P tradeoff. In contrast, low to moderate N inputs increased both AMF parameters, corresponding to the increasing N:P ratio. Yet, high N inputs reduced AMF colonization and biomass, and the magnitudes of N‐led inhibition were similar to those under acid additions that induced comparable changes in soil pH. Structural equation modeling further showed that while soil N:P stoichiometry primarily controlled the effect of P addition on AMF, N‐induced soil acidity overtook the N:P stoichiometry under high N inputs and dominated the effects of reactive N on AMF. In addition, AMF community composition in roots was more dependent on host plants and unresponsive to changes in soil nutrients. We further proposed a comprehensive framework that integrates biological and geochemical effects of reactive N and P inputs on AMF. Together, these results indicate that while the C‐P tradeoff controls P suppression of AMF, N‐induced acidification dominates the N inhibition. Our findings suggest that incorporation of geochemical impacts of N and P inputs would facilitate modeling efforts to project mycorrhizal impact on plant interactions and soil C balance under future nutrient enrichment scenarios.

Machine learning approaches for rice crop yield predictions using time-series satellite data in Taiwan - Nguyen-Thanh Son; Chi-Farn Chen; Cheng-Ru Chen; Horng-Yuh Guo; Youg-Sing Cheng; Shu-Ling Chen; Huan-Sheng Lin; Shih-Hsiang Chen (International Journal of Remote Sensing, 2020)

Real-Time Prediction of Large-Scale Ship Model Vertical Acceleration Based on Recurrent Neural Network - Yumin Su; Jianfeng Lin; Dagang Zhao; Chunyu Guo; Chao Wang; Hang Guo (Journal of Marine Science and Engineering, 2020)
In marine environments, ships are bound to be disturbed by several external factors, which can cause stochastic fluctuations and strong nonlinearity in the ship motion. Predicting ship motion is pivotal to ensuring ship safety and providing early warning of risks. This report proposes a real-time ship vertical acceleration prediction algorithm based on the long short-term memory (LSTM) and gated recurrent units (GRU) models of a recurrent neural network. The vertical acceleration time history data at the bow, middle, and stern of a large-scale ship model were obtained by performing a self-propulsion test at sea, and the original data were pre-processed by resampling and normalisation via Python. The prediction results revealed that the proposed algorithm could accurately predict the acceleration time history data of the large-scale ship model, and the root mean square error between the predicted and real values was no greater than 0.1. The optimised multivariate time series prediction program could reduce the calculation time by approximately 55% compared to that of a univariate time series prediction program, and the run time of the GRU model was better than that of the LSTM model.

One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko - Wan-Rong Niu; Cong-Liang Guo; Deng-Ji Lou; Rui-Ting Li; Qiao Xiang; Yu-Lin Zou; Xiu-Ming Cui; Xiao-Yan Yang (Natural Product Research, 2020)

MiRNAs-Modulation of Nrf2 Signaling Networks in Regulation Oxidative Stress of Chinese Perch Skeletal Muscle After Fasting Treatment - Ping Wu; Lin Chen; Jia Cheng; Yaxiong Pan; Xinhong Guo; Wuying Chu; Jianshe Zhang; Xuanming Liu (Marine Biotechnology, 2020)

Apical ectodermal ridge regulates three principal axes of the developing limb - Guo-hao Lin; Lan Zhang (Journal of Zhejiang University-SCIENCE B, 2020)

Grape seed proanthocyanidin extract ameliorates hepatic lipid accumulation and inflammation in grass carp (Ctenopharyngodon idella) - Rong-Hua Lu; Chao-Bin Qin; Feng Yang; Wen-Ya Zhang; Yu-Ru Zhang; Guo-Kun Yang; Li-Ping Yang; Xiao-Lin Meng; Xiao Yan; Guo-Xing Nie (Fish Physiology and Biochemistry, 2020)

Complete Genome of Vibrio neocaledonicus CGJ02-2, An active Compounds Producing Bacterium Isolated from South China Sea - Lin Tan; Isabel Gómez-Betancur; Suxia Guo; Yu Ge; Jianping Zhao; Chang Chen; Nan Wang (Current Microbiology, 2020)

Climatology of Tibetan Plateau vortices derived from multiple reanalysis datasets - Zhiqiang Lin; Weidong Guo; La Jia; Xiuping Yao; Zhenbo Zhou (Climate Dynamics, 2020)

Selenium Deficiency in Chickens Induces Intestinal Mucosal Injury by Affecting the Mucosa Morphology, SIgA Secretion, and GSH-Px Activity - Xianjing He; Yucai Lin; Shuai Lian; Dongbo Sun; Donghua Guo; Jianfa Wang; Rui Wu (Biological Trace Element Research, 2020)

Rapid and accurate initial alignment of the low-cost MEMS IMU chip dedicated for tilted RTK receiver - Qijin Chen; Huan Lin; Ruonan Guo; Xiaoji Niu (GPS Solutions, 2020)

Small RNA profiling reveal regulation of microRNAs in field peanut pod rot pathogen infection - Mian Wang; Chao-xin Zhang; Li-juan Pan; Tong Wang; Na Chen; Ming-na Chen; Zhen Yang; Xin-gang Guo; Shan-lin Yu; Xiao-yuan Chi (Biologia, 2020)

Epidemiological and phylogenetic analysis of canine kobuviruses in Tangshan, China - Zhaoyang Wang; Yajun Jiang; Xueting Liu; Weidong Lin; Qianqian Feng; Ting Xin; Xiaoyu Guo; Shaohua Hou; Hongfei Zhu; Hong Jia (Archives of Virology, 2020)

Nutrient factor-dependent performance of bacterial quorum sensing system during population evolution - Kelei Zhao; Jing Li; Yang Yuan; Jiafu Lin; Xinrong Wang; Yidong Guo; Yiwen Chu (Archives of Microbiology, 2020)

Simulation and Improvements of Oceanic Circulation and Sea Ice by the Coupled Climate System Model FGOALS-f3-L - Yuyang Guo; Yongqiang Yu; Pengfei Lin; Hailong Liu; Bian He; Qing Bao; Bo An; Shuwen Zhao; Lijuan Hua (Advances in Atmospheric Sciences, 2020)

Overview of the CMIP6 Historical Experiment Datasets with the Climate System Model CAS FGOALS-f3-L - Yuyang Guo; Yongqiang Yu; Pengfei Lin; Hailong Liu; Bian He; Qing Bao; Shuwen Zhao; Xiaowei Wang (Advances in Atmospheric Sciences, 2020)
The three-member historical simulations by the Chinese Academy of Sciences Flexible Global Ocean-Atmosphere-Land System model, version f3-L (CAS FGOALS-f3-L), which is contributing to phase 6 of the Coupled Model Intercomparison Project (CMIP6), are described in this study. The details of the CAS FGOALS-f3-L model, experiment settings and output datasets are briefly introduced. The datasets include monthly and daily outputs from the atmospheric, oceanic, land and sea-ice component models of CAS FGOALS-f3-L, and all these data have been published online in the Earth System Grid Federation (ESGF, https://esgf-node.llnl.gov/projects/cmip6/ ). The three ensembles are initialized from the 600th, 650th and 700th model year of the preindustrial experiment (piControl) and forced by the same historical forcing provided by CMIP6 from 1850 to 2014. The performance of the coupled model is validated in comparison with some recent observed atmospheric and oceanic datasets. It is shown that CAS FGOALS-f3-L is able to reproduce the main features of the modern climate, including the climatology of air surface temperature and precipitation, the long-term changes in global mean surface air temperature, ocean heat content and sea surface steric height, and the horizontal and vertical distribution of temperature in the ocean and atmosphere. Meanwhile, like other state-of-the-art coupled GCMs, there are still some obvious biases in the historical simulations, which are also illustrated. This paper can help users to better understand the advantages and biases of the model and the datasets.

Xanthatin mediates G 2 /M cell cycle arrest, autophagy and apoptosis via ROS/XIAP signaling in human colon cancer cells - Ya-di Geng; Lei Zhang; Guo-Yu Wang; Xiao-Jun Feng; Zhao-Lin Chen; Ling Jiang; Ai-Zong Shen (Natural Product Research, 2020)

Preliminary results of mixed afforestation experiment of Betula alnoides Buch.-Ham. ex D. Don in Southern Fujian China - Bihua Chen; Bijiang Fang; Guobiao Chen; Yuqing Lin; Xinhua Dai; Yinzhen Liao; Xiaolong Hong; Qinggen Chen; Yongjian Lin; Juan Zhang; Jie Zeng; Junjie Guo; et al. (Vegetos, 2020)

RES transformation for biosynthesis and detoxification - Jin-Quan Huang; Jia-Ling Lin; Xiao-Xiang Guo; Xiu Tian; Ye Tian; Xiao-Xia Shangguan; Ling-Jian Wang; Xin Fang; Xiao-Ya Chen (Science China Life Sciences, 2020)

Noninvasive ultrasound deep brain stimulation of nucleus accumbens induces behavioral avoidance - Lili Niu; Yanchen Guo; Zhengrong Lin; Zhe Shi; Tianyuan Bian; Lin Qi; Long Meng; Anthony A. Grace; Hairong Zheng; Ti-Fei Yuan (Science China Life Sciences, 2020)

Macrophage–NLRP3 Inflammasome Activation Exacerbates Cardiac Dysfunction after Ischemic Stroke in a Mouse Model of Diabetes - Hong-Bin Lin; Guan-Shan Wei; Feng-Xian Li; Wen-Jing Guo; Pu Hong; Ya-Qian Weng; Qian-Qian Zhang; Shi-Yuan Xu; Wen-Bin Liang; Zhi-Jian You; Hong-Fei Zhang (Neuroscience Bulletin, 2020)

Correction to: Investigating the age composition of Indo-Pacific humpback dolphins in the Pearl River Estuary based on their pigmentation pattern - Lang Guo; Wenzhi Lin; Chen Zeng; Dingyu Luo; Yuping Wu (Marine Biology, 2020)

Evolution of Neolithic site distribution (9.0–4.0 ka BP) in Anhui, East China - Li Wu; Xiaoling Sun; Wei Sun; Cheng Zhu; Tongxin Zhu; Shuguang Lu; Hui Zhou; Qingchun Guo; Houchun Guan; Wei Xie; Rui Ke; Guiping Lin (Journal of Geographical Sciences, 2020)

Undrained monotonic shear behavior of marine soft clay after long-term cyclic loading - Lin Guo; Hongxu Jin; Jun Wang; Li Shi (Marine Georesources & Geotechnology, 2020)

Multiplex RT–PCR Assay for the Simultaneous Detection and Identification of Five Sugarcane Viruses - Xiao-Yan Feng; Wen-Zhi Wang; Lin-Bo Shen; Jun-Gang Wang; Guo-Ru Xiong; Cui-Lian Feng; Ting-Ting Zhao; Shu-Zhen Zhang (Sugar Tech, 2020)

A shadow detection and removal method for fruit recognition in natural environments - Rongbin Bu; Juntao Xiong; Shumian Chen; Zhenhui Zheng; Wentao Guo; Zhengang Yang; Xiaoyun Lin (Precision Agriculture, 2020)

Nitrogen and phosphorus co-starvation inhibits anthocyanin synthesis in the callus of grape berry skin - Hui-Zhen Zheng; Huan Wei; Shui-Huan Guo; Xin Yang; Ming-Xin Feng; Xu-Qiao Jin; Yu-Lin Fang; Zhen-Wen Zhang; Teng-Fei Xu; Jiang-Fei Meng (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Alfalfa MsCBL4 enhances calcium metabolism but not sodium transport in transgenic tobacco under salt and saline–alkali stress - Yimin An; Xiao-Xue Yang; Lishuang Zhang; Jun Zhang; Binghao Du; Lin Yao; Xiu-ting Li; Changhong Guo (Plant Cell Reports, 2020)

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study - Shao-rui Hao; Ren Yan; Shan-yan Zhang; Jiang-shan Lian; Huan Cai; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Herpud1 deficiency could reduce amyloid-β40 expression and thereby suppress homocysteine-induced atherosclerosis by blocking the JNK/AP1 pathway - Feidan Gao; Jie Zhang; Tingjuan Ni; Na Lin; Hui Lin; Hangqi Luo; Hangyuan Guo; Jufang Chi (Journal of Physiology and Biochemistry, 2020)

Enhancement of the activity of Cu/TiO2 catalyst by Eu modification for selective catalytic reduction of NOx with NH3 - Yuan-zhen Liu; Qi-yan Xu; Rui-tang Guo; Chao-peng Duan; Gui-lin Wu; Yu-fang Miao; Jing-wen Gu (Environmental Science and Pollution Research, 2020)

Nakamurella albus sp. nov.: A Novel Actinobacterium Isolated from a Lichen Sample - Long-Qian Jiang; De-Feng An; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Lei Lang; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2020)

Functional community composition has less environmental variability than taxonomic composition in straw-degrading bacteria - Yuanyuan Bao; Zhiying Guo; Ruirui Chen; Meng Wu; Zhongpei Li; Xiangui Lin; Youzhi Feng (Biology and Fertility of Soils, 2020)

A new 5α,8α-epidioxysterol with immunosuppressive activity from the South China Sea soft coral Sinularia sp. - Min Yang; Lin-Fu Liang; Heng Li; Wei Tang; Yue-Wei Guo (Natural Product Research, 2020)

An Efficient Catalytic Composite Material of Mesoporous Carbon Loaded Nano Zero-Valent Iron as an Activator for the Degradation of Sulfadiazine - Liangbo Zhang; Yinghui Guo; Ruzhen Xie; Lin Chen; Wenju Jiang; Xia Jiang (Water, Air, & Soil Pollution, 2020)

Technology on sleep surgery - Wei Zhao; Lianhua Zhao; Yuanqing Zhao; Zaiyu Guo; Jialiang Guo; Cunguo Lin; Rayleigh Ping-Ying Chiang (Sleep and Biological Rhythms, 2020)

Beyond resource limitation: an expanded test of the niche dimension hypothesis for multiple types of niche axes - Xuebin Yan; Jeffrey Diez; Kailing Huang; Shaopeng Li; Xi Luo; Xinyu Xu; Fanglong Su; Lin Jiang; Hui Guo; Shuijin Hu (Oecologia, 2020)

Ecological risk evaluation and source apportionment of heavy metals in park playgrounds: a case study in Xi’an, Shaanxi Province, a northwest city of China - Bin Guo; Yi Su; Lin Pei; Xiaofeng Wang; Bo Zhang; Dingming Zhang; Xiaoxia Wang (Environmental Science and Pollution Research, 2020)

The chemical constituents from the active fractions of Eleutherine bulbosa with their antimicrobial activity - Hai Jiang; Wen-Jing Man; A-Jiao Hou; Lin Yang; Xu-Dong Xing; Mei-Ling Yan; Xin-Yue Guo; Liu Yang (Natural Product Research, 2020)

3D-QSAR, HQSAR, molecular docking, and new compound design study of 1,3,6-trisubstituted 1,4-diazepan-7-ones as human KLK7 inhibitors - Le Fu; Yi Chen; Chun-mei Xu; Tao Wu; Hong-mei Guo; Zhi-hua Lin; Rui Wang; Mao Shu (Medicinal Chemistry Research, 2020)

Faba Bean Organs Differed in Their Effects on Maize Seed Germination Rate and Soil Microbial Activities as well as Their Decomposition Patterns in a Regosol Soil - Zhibin He; Luhua Yao; Xuefeng Zhang; Yang Li; Dengke Wang; Lin Kang; Cui Cui; Aiying Huang; Ruiji Yang; Qianlin Xiao; Yanjun Guo (Journal of Soil Science and Plant Nutrition, 2020)

Selective catalytic reduction of NOx by NH3 over CeVO4-CeO2 nanocomposite - Chao-peng Duan; Rui-tang Guo; Gui-lin Wu; Wei-guo Pan (Environmental Science and Pollution Research, 2020)

Effects of Hyperbaric Oxygen Therapy on Acute Myocardial Infarction Following Carbon Monoxide Poisoning - Chien-Cheng Huang; Chung-Han Ho; Yi-Chen Chen; Chien-Chin Hsu; Hung-Jung Lin; Jhi-Joung Wang; Shih-Bin Su; How-Ran Guo (Cardiovascular Toxicology, 2020)

Influence of canopy and topographic position on soil moisture response to rainfall in a hilly catchment of Three Gorges Reservoir Area, China - Muxing Liu; Qiuyue Wang; Li Guo; Jun Yi; Henry Lin; Qing Zhu; Bihang Fan; Hailin Zhang (Journal of Geographical Sciences, 2020)

Three-directional analytic signal analysis and interpretation of magnetic gradient tensor - Can-wen Guo; Zhe Xing; Lin-fei Wang; Yong Ma; Heng-fei Huan (Applied Geophysics, 2020)

Two new aromatic polyketides from a deep-sea fungus Penicillium sp. SCSIO 06720 - Cui Guo; Xiu-Ping Lin; Sheng-Rong Liao; Bin Yang; Xue-Feng Zhou; Xian-Wen Yang; Xin-Peng Tian; Jun-Feng Wang; Yong-Hong Liu (Natural Product Research, 2020)

Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure - Jiang-shan Lian; Huan Cai; Shao-rui Hao; Xi Jin; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Shan-yan Zhang; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

The response of warm-season precipitation extremes in China to global warming: an observational perspective from radiosonde measurements - Jianping Guo; Yan Yan; Dandan Chen; Yanmin Lv; Yi Han; Xiaoran Guo; Lin Liu; Yucong Miao; Tianmeng Chen; Ji Nie; Panmao Zhai (Climate Dynamics, 2020)

Construction expression and immunogenicity of a novel trivalent outer membrane protein (OmpU‐A‐II) from three bacterial pathogens in Japanese eels ( Anguilla japonica ) - Jinping Zhao; Liqun Wu; Shaowei Zhai; Peng Lin; Songlin Guo (Journal of Fish Diseases, 2020)
Vibrio vulnificus , Edwardsiella anguillarum and Aeromonas hydrophila are three common bacterial pathogens in cultivated eels. To protect farming eels from infection by these pathogens, a trivalent outer membrane protein (OMP) containing partial sequences of OmpU from V. vulnificus , OmpA from E. anguillarum and OmpII from A. hydrophila was expressed and purified; then, the OMP was used as a vaccine to immunize Japanese eels ( Anguilla japonica ). Whole‐blood cell proliferation, antibody titres and complement and lysozyme activities were detected at different days post‐immunization (dpi), and the relative per cent survival (RPS) was determined after eels were infected with V. vulnificus , E. anguillarum or A. hydrophila at 28 dpi. The results showed that the OMP significantly stimulates the antibody titres. At 14 days after the challenge (i.e. at 28 dpi), the RPS of OMP against V. vulnificus, E. anguillarum and A. hydrophila was 20%, 70% and 11.1%, respectively. The construction, expression and immunogenicity of a trivalent Omp were reported for the first time, and this study will provide a valuable reference for the development of fish multiplex vaccines.

Sedimentary environment and facies of the Huagang Formation in the northern central Xihu Depression, East China Sea Basin, China - Z. X. Zhao; C. M. Dong; C. Y. Lin; X. G. Zhang; X. Huang; B. J. Li; W. Guo; Z. Q. Zhu (Australian Journal of Earth Sciences, 2020)

Co-infections of SARS-CoV-2 with multiple common respiratory pathogens in infected patients - Dachuan Lin; Lei Liu; Mingxia Zhang; Yunlong Hu; Qianting Yang; Jiubiao Guo; Yongchao Guo; Youchao Dai; Yuzhong Xu; Yi Cai; Xinchun Chen; Zheng Zhang; et al. (Science China Life Sciences, 2020)

Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs. 3 doses in young women - Yue-Mei Hu; Meng Guo; Chang-Gui Li; Kai Chu; Wen-Gang He; Jing Zhang; Jian-Xiang Gu; Juan Li; Hui Zhao; Xiang-Hong Wu; BiZhen Lin; Zhi-Jie Lin; et al. (Science China Life Sciences, 2020)

Identification of Candidate Growth-Related SNPs and Genes Using GWAS in Brown-Marbled Grouper (Epinephelus fuscoguttatus) - Yang Yang; Lina Wu; Xi Wu; Bijun Li; Wenhua Huang; Zhuoying Weng; Zixuan Lin; Leling Song; Yin Guo; Zining Meng; Xiaochun Liu; Junhong Xia (Marine Biotechnology, 2020)

Investigating the age composition of Indo-Pacific humpback dolphins in the Pearl River Estuary based on their pigmentation pattern - Lang Guo; Wenzhi Lin; Chen Zeng; Dingyu Luo; Yuping Wu (Marine Biology, 2020)

Mechanisms behind soil N dynamics following cover restoration in degraded land in subtropical China - Xiangzhou Zheng; Cheng Lin; Baoling Guo; Juhua Yu; Hong Ding; Shaoyun Peng; Jinbo Zhang; Eric Ireland; Deli Chen; Christoph Müller; Yushu Zhang (Journal of Soils and Sediments, 2020)

Correction to: Whole Exome Sequencing Identifies Two Novel Mutations in the Reticulon 4–Interacting Protein 1 Gene in a Chinese Family with Autosomal Recessive Optic Neuropathies - Xiao-Huan Zou; Xin-Xin Guo; Hui-Zhen Su; Chong Wang; En-Lin Dong; Ning Wang; Wan-Jin Chen; Qi-Jie Zhang (Journal of Molecular Neuroscience, 2020)

lncRNA-XIST protects the hypoxia-induced cardiomyocyte injury through regulating the miR-125b-hexokianse 2 axis - Ji-Lin Fan; Ting-Ting Zhu; Zhen-Yu Xue; Wen-Qing Ren; Jing-Qi Guo; Heng-Yi Zhao; Shi-Liang Zhang (In Vitro Cellular & Developmental Biology - Animal, 2020)

Effects of small nucleolar RNA SNORD44 on the proliferation, apoptosis and invasion of glioma cells - Xian-Ru Xia; Wen-Cui Li; Zong-Tao Yu; Jie Li; Chun-Yan Peng; Li Jin; Guo-Lin Yuan (Histochemistry and Cell Biology, 2020)

Impacts of elevated temperature and pCO2 on the brooded larvae of Pocillopora damicornis from Luhuitou Reef, China: evidence for local acclimatization - Lei Jiang; Ming-Lan Guo; Fang Zhang; Yu-Yang Zhang; Guo-Wei Zhou; Xin-Ming Lei; Xiang-Cheng Yuan; You-Fang Sun; Tao Yuan; Lin Cai; Jian-Sheng Lian; Sheng Liu; et al. (Coral Reefs, 2020)

Swelling characteristics of andesite foundation induced by water immersion and their influence on ballastless track subgrade - Jun-yi Duan; Guo-lin Yang; Min Hu; Xiao-qin Lei; Yu-liang Lin (Journal of Mountain Science, 2020)

Next-generation sequencing technology as a powerful detection and semi-quantitative method for herpes simplex virus type 1 in pediatric encephalitis - Lin-lin Liu; Ling-yun Guo; Jie Dong; Wen-hua Huang; Li Zhao; Bing Liu; Xi-xi Zhang; Yong-qiang Jiang; Gang Liu (Journal of NeuroVirology, 2020)

Hybrid constellation design using a genetic algorithm for a LEO-based navigation augmentation system - Fujian Ma; Xiaohong Zhang; Xingxing Li; Junlong Cheng; Fei Guo; Jiahuan Hu; Lin Pan (GPS Solutions, 2020)

The roles of moisture transports in intraseasonal precipitation during the preflood season over South China - Qu‐cheng Chu; Qi‐guang Wang; Guo‐lin Feng (International Journal of Climatology, 2020)
The roles of moisture sources and transport in intraseasonal precipitation variabilities during the preflood season over South China are complex and different. In this paper, ERA‐Interim reanalysis data that were collected four times daily from 1979 to 2017 are used to analyse the variation and influence of moisture transport in intraseasonal precipitation during the preflood season over South China. Using the Hybrid Single‐Particle Lagrangian Integrated Trajectory model, fixed atmospheric moisture sources are defined: land area source (LD source), Indian Ocean source (IO source), Pacific Ocean source (PO source), South China Sea source (SCS source), and South China source (SC source). Sea source moisture transport accounts for more than 75% of the total precipitation during the preflood season, which is the most important moisture source in South China. For April, southeasterly moisture transport, which includes PO source and SCS source moisture transports, is the major moisture transport over South China. Then, the IO source and SCS source precipitation increased significantly during May. During June, the IO source precipitation accounted for 43.75% of the total precipitation, thus dominating precipitation over South China. In addition, there is a significant difference in the interdecadal variation in the preflood season precipitation before and after the Indian summer monsoon onset. Before the Indian summer monsoon onset, the land‐sea thermal contrast decreased, which led to a significant interdecadal reduction in the IO source, PO source, and SCS source moisture transports. After the Indian summer monsoon onset, the increase in IO source moisture transport is the primary cause of the interdecadal increase in precipitation over South China.

Numerical Simulation of Large Wave Heights from Super Typhoon Nepartak (2016) in the Eastern Waters of Taiwan - Shih-Chun Hsiao; Hongey Chen; Han-Lun Wu; Wei-Bo Chen; Chih-Hsin Chang; Wen-Dar Guo; Yung-Ming Chen; Lee-Yaw Lin (Journal of Marine Science and Engineering, 2020)
Super Typhoon Nepartak (2016) was used for this case study because it is the most intense typhoon that made landfall in Taiwan in the past decade. Winds extracted from the Climate Forecast System version 2 (CFSV2) and ERA5 datasets and merged with a parametric typhoon model using two hybrid techniques served as the meteorological conditions for driving a coupled wave-circulation model. The computed significant wave heights were compared with the observations recorded at three wave buoys in the eastern waters of Taiwan. Model performance in terms of significant wave height was also investigated by employing the CFSV2 winds under varying spatial and temporal resolutions. The results of the numerical experiments reveal that the simulated storm wave heights tended to decrease significantly due to the lower spatial resolution of the hourly winds from the CFSV2 dataset; however, the variations in the storm wave height simulations were less sensitive to the temporal resolution of the wind field. Introducing the combination of the CFSV2 and the parametric typhoon winds greatly improved the storm wave simulations, and similar phenomena can be found in the exploitation of the ERA5 dataset blended into the parametric wind field. The overall performance of the hybrid winds derived from ERA5 was better than that from the CFSV2, especially in the outer region of Super Typhoon Nepartak (2016).

Cytotoxic components from the Xisha sponge Fascaplysinopsis reticulata - Guo-Fei Qin; Xu-Li Tang; Nicole J. de Voogd; Ping-Lin Li; Guo-Qiang Li (Natural Product Research, 2020)

Microbial synthesis of functional odd-chain fatty acids: a review - Lin-Shang Zhang; Shan Liang; Min-Hua Zong; Ji-Guo Yang; Wen-Yong Lou (World Journal of Microbiology and Biotechnology, 2020)

An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction - Mengxi Guo; Chengliang Zhou; Gufeng Xu; Lin Tang; Yechun Ruan; Ying Yu; Xianhua Lin; Dandan Wu; Hao Chen; Priscilla Yu; Luyang Jin; Yinyu Wang; et al. (Science China Life Sciences, 2020)

Effects of Dietary Supplementation of Recombinant Plectasin on Growth Performance, Intestinal Health and Innate Immunity Response in Broilers - Jing Lin Ma; Li Hua Zhao; Dan Dan Sun; Jing Zhang; Yong Peng Guo; Zhi Qiang Zhang; Qiu Gang Ma; Cheng Ji; Li Hong Zhao (Probiotics and Antimicrobial Proteins, 2020)

Effects of Chronic Ephedrine Toxicity on Functional Connections, Cell Apoptosis, and CREB-Related Proteins in the Prefrontal Cortex of Rhesus Monkeys - Shouxing Duan; Ye Ma; Lei Xie; Lian Zheng; Jinzhuang Huang; Ruiwei Guo; Zongbo Sun; Yao Xie; Junyao Lv; Zhirong Lin; Shuhua Ma (Neurotoxicity Research, 2020)

Potential Genes Related to Levofloxacin Resistance in Mycobacterium tuberculosis Based on Transcriptome and Methylome Overlap Analysis - Hai-cheng Li; Hui-xin Guo; Tao Chen; Wei Wang; Zhu-hua Wu; Liang Chen; Hui-zhong Wu; Gao-po Xu; Xun-xun Chen; Lin Zhou (Journal of Molecular Evolution, 2020)
Drug-resistant Mycobacterium tuberculosis ( M. tuberculosis ) has become an increasingly serious public health problem and has complicated tuberculosis (TB) treatment. Levofloxacin (LOF) is an ideal anti-tuberculosis drug in clinical applications. However, the detailed molecular mechanisms of LOF-resistant M. tuberculosis in TB treatment have not been revealed. Our study performed transcriptome and methylome sequencing to investigate the potential biological characteristics of LOF resistance in M. tuberculosis H37Rv. In the transcriptome analysis, 953 differentially expressed genes (DEGs) were identified; 514 and 439 DEGs were significantly downregulated and upregulated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 97 pathways were enriched in this study. In the methylome analysis, 239 differentially methylated genes (DMGs) were identified; 150 and 89 DMGs were hypomethylated and hypermethylated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 74 pathways were enriched in this study. The overlap study suggested that 25 genes were obtained. It was notable that nine genes expressed downregulated mRNA and upregulated methylated levels, including pgi , fadE4 , php , cyp132 , pckA , rpmB1 , pfkB , acg , and ctpF , especially cyp132 , pckA , and pfkB , which were vital in LOF-resistant M. tuberculosis H37Rv. The overlapping genes between transcriptome and methylome could be essential for studying the molecular mechanisms of LOF-resistant M. tuberculosis H37Rv. These results may provide informative evidence for TB treatment with LOF.

Southward subduction of the Bangong-Nujiang Tethys Ocean: insights from ca. 161–129 Ma arc volcanic rocks in the north of Lhasa terrane, Tibet - Yue Tang; Qing-Guo Zhai; Pei-Yuan Hu; Sun-Lin Chung; Xu-Chang Xiao; Hai-Tao Wang; Zhi-Cai Zhu; Wei Wang; Hao Wu; Hao-Yang Lee (International Journal of Earth Sciences, 2020)

Global buckling prevention of reduced-core-length buckling-restrained braces: theoretical and numerical investigations - Jing-Zhong Tong; Yan-Lin Guo; Wen-Hao Pan; Min-Hui Shen; Peng Zhou (Bulletin of Earthquake Engineering, 2020)

Rostral intralaminar thalamic deep brain stimulation ameliorates memory deficits and dendritic regression in β-amyloid-infused rats - Sheng-Tzung Tsai; Shin-Yuan Chen; Shinn-Zong Lin; Guo-Fang Tseng (Brain Structure and Function, 2020)

(±)-Quassidine K, a pair of cytotoxic bis- β -carboline alkaloid enantiomers from Picrasma quassioides - Xin-Ming Guo; Fei Li; Fang-Fang Zheng; Na-Na Gong; Yan Li; Wen-Zhou Feng; Lin Tian (Natural Product Research, 2020)

Analysis of Cerebrospinal Fluid Soluble TREM2 and Polymorphisms in Sporadic Parkinson’s Disease in a Chinese Population - Guoyou Peng; Jiewen Qiu; Hanqun Liu; Miaomiao Zhou; Shuxuan Huang; Wenyuan Guo; Yuwan Lin; Xiang Chen; Zhe Li; Guihua Li; Wenlong Zhang; Yunlong Zhang; et al. (Journal of Molecular Neuroscience, 2020)

High dietary lipid level alters the growth, hepatic metabolism enzyme, and anti-oxidative capacity in juvenile largemouth bass Micropterus salmoides - Yue-Lang Zhou; Jia-Ling Guo; Ren-Jun Tang; Hui-Jia Ma; Yong-Jun Chen; Shi-Mei Lin (Fish Physiology and Biochemistry, 2020)