Lessons to inform interventions to reduce racial and ethnic health disparities within hematologic malignancies - Olivia M. Lin; Megan Shen; Christopher I. Li; Stephanie J. Lee (Cancer Causes & Control, 2023)

Nanorod reassembling on a sprayed SERS substrate under confined evaporation inducing ultrasensitive TPhT detection - Lin Chang; Xiaohong Liu; Chong-Yew Lee; Wei Zhang (Analytica Chimica Acta, 2023)

High-performance peptide and disulfide mapping by direct injection of intact proteins using on-line coupled UV-liquid chromatography microdroplet mass spectrometry (UVLC-MMS) - Chin-Ming Kuo; Hung-Hsiang Jen; Fung-Yu Chen; Mohsen Akbarian; Tai-Hong Ou; Kang-Yu Liu; Jung-Lee Lin; Shu-Hui Chen (Analytica Chimica Acta, 2023)

BioDeepTime: A database of biodiversity time series for modern and fossil assemblages - Jansen Smith; Marina C. Rillo; Ádám T. Kocsis; Maria Dornelas; David Fastovich; Huai‐Hsuan M. Huang; Lukas Jonkers; Wolfgang Kiessling; Qijian Li; Lee Hsiang Liow; Miranda Margulis‐Ohnuma; Stephen Meyers; et al. (Global Ecology and Biogeography, 2023)
Motivation We have little understanding of how communities respond to varying magnitudes and rates of environmental perturbations across temporal scales. BioDeepTime harmonizes assemblage time series of presence and abundance data to help facilitate investigations of community dynamics across timescales and the response of communities to natural and anthropogenic stressors. BioDeepTime includes time series of terrestrial and aquatic assemblages of varying spatial and temporal grain and extent from the present‐day to millions of years ago. Main Types of Variables Included BioDeepTime currently contains 7,437,847 taxon records from 10,062 assemblage time series, each with a minimum of 10 time steps. Age constraints, sampling method, environment and taxonomic scope are provided for each time series. Spatial Location and Grain The database includes 8752 unique sampling locations from freshwater, marine and terrestrial ecosystems. Spatial grain represented by individual samples varies from quadrats on the order of several cm 2 to grid cells of ~100 km 2 . Time Period and Grain BioDeepTime in aggregate currently spans the last 451 million years, with the 10,062 modern and fossil assemblage time series ranging in extent from years to millions of years. The median extent of modern time series is 18.7 years and for fossil series is 54,872 years. Temporal grain, the time encompassed by individual samples, ranges from days to tens of thousands of years. Major Taxa and Level of Measurement The database contains information on 28,777 unique taxa with 4,769,789 records at the species level and another 271,218 records known to the genus level, including time series of benthic and planktonic foraminifera, coccolithophores, diatoms, ostracods, plants (pollen), radiolarians and other invertebrates and vertebrates. There are to date 7012 modern and 3050 fossil time series in BioDeepTime. Software Format SQLite, Comma‐separated values.

Exposure to incense burning, biomarkers, and the physical health of temple workers in Taiwan - Su-Er Guo; Pamela A. Ratner; Sung-Chih Tseng; Chieh-Mo Lin; Miao-Ching Chi; Chiang-Wen Lee; Ying-Chun Yu (Environmental Science and Pollution Research, 2023)
Incense burning releases heavy particulate matter (PM) and nitrogen dioxide (NO 2 ), known to have adverse effects on human health. Long-term exposure to PM and NO 2 increases inflammatory cytokine levels and can induce respiratory diseases. This study examined the association between incense burning exposure and the health status, especially inflammatory biomarkers, of temple workers and volunteers in Taiwan. The longitudinal observational study compared adult temple workers and volunteers, with long-term incense burning exposure, to residents from outpatient clinics in the Chiayi area. Forced expiratory volume in 1 s (FEV1) and serum and exhaled breath condensate (EBC) cytokines were assessed. Nonparametric Mann-Whitney U tests were used to compare cytokine levels of the exposure and control groups during the cold and hot weather seasons. FEV1 was significantly more diminished in the exposed group than in the control group during the cold season. Exposure status was associated with greater hot-cold seasonal differences in serum interleukins (IL)-1β (regression coefficient ( B ) = 6.6, 95% confidence interval (CI) = 5.0 to 8.3, p < .001), IL17-A ( B = 2.4, 95% CI = 0.3 to 4.5, p = .03), and plasminogen activator inhibitor [PAI]-1 ( B = 5.4, 95% CI = 1.5 to 9.3, p = .009). After adjusting for confounders, the groups’ serum levels of IL-1β, IL-17A, and PAI-1 significantly differed. EBC cytokines did not show significant differences. Elevated levels of IL-1β, IL17-A, and PAI-1 have been associated with various autoinflammatory syndromes and diseases. Given the cultural significance of incense burning, culturally sensitive interventions, including education, policy development, and program implementation, are crucial to protect individuals’ health, especially temple workers, from the adverse effects of exposure, addressing the manufacture, importation, and sale of incense.

Study on leaching characteristics and biotoxicity of porous asphalt with biochar fillers - Jiawen Liu; Hui Li; John Harvey; Gordon Airey; Sijie Lin; Stephanie Ling Jie Lee; Yitan Zhou; Bing Yang (Transportation Research Part D: Transport and Environment, 2023)

Estimating hydrogeological parameters at groundwater level observation wells without pumping well information - Hwa-Lung Yu; Shih-Yao Lee; Hua-Ting Tseng; Ying-Fan Lin (Journal of Hydrology, 2023)

Temporal transition trends of cord blood lead levels in various human development index countries and in the Taipei metropolitan area - Yaw-Huei Hwang; Hui-Chu Wu; Ming-Kwang Shyu; Chien-Nan Lee; Shin-Yu Lin; Pau-Chung Chen; Hung-Yi Chuang; Pei-Wen Lin; Tso-Hsien Wu; Yen-Tzu Chen (Environmental Pollution, 2023)

Detecting landslide vulnerability using anisotropic microtremors and vulnerability index - Po-Hsiang Liu; Jian-Hong Wu; Der-Her Lee; Yu-Hsuan Lin (Engineering Geology, 2023)

Toward ultra-high efficiency tandem OLEDs: Benzothiazole-based bipolar hosts and specific device architectures - Jui-Ming Wang; Ting-Chun Lee; Chia-Chen Chung; Wun-Yu Chen; Sih-Yu Wu; Yan-Ding Lin; Yuan Jay Chang; Chin-Wei Lu; Chih-Hao Chang (Chemical Engineering Journal, 2023)

Simultaneous removal of sulfamethoxazole during fermentative production of short-chain fatty acids - Yue Wang; Rongrong Lin; Yushuang Cao; Shuangfei Li; Rong Cui; Wanqian Guo; Shih-Hsin Ho; Yoong Kit Leong; Duu-Jong Lee; Jo-Shu Chang (Bioresource Technology, 2023)

High carriage rate of extended‐spectrum β‐lactamase Enterobacterales and diarrheagenic Escherichia coli in healthy donor screening for fecal microbiota transplantation - Chien Chuang; Kuei-Chuan Lee; Yen-Po Wang; Pei-Chang Lee; Tien-En Chang; Yi-Hsiang Huang; Yi-Tsung Lin; Ming-Chih Hou (European Journal of Clinical Microbiology & Infectious Diseases, 2023)

Highly-specific aptamer targeting SARS-CoV-2 S1 protein screened on an automatic integrated microfluidic system for COVID-19 diagnosis - Hung-Bin Wu; Chih-Hung Wang; Yi-Da Chung; Yan-Shen Shan; Ying-Jun Lin; Huey-Pin Tsai; Gwo-Bin Lee (Analytica Chimica Acta, 2023)

Edge-based wireless imaging system for continuous monitoring of insect pests in a remote outdoor mango orchard - Dan Jeric Arcega Rustia; Wei-Che Lee; Chen-Yi Lu; Ya-Fang Wu; Pei-Yu Shih; Sheng-Kuan Chen; Jui-Yung Chung; Ta-Te Lin (Computers and Electronics in Agriculture, 2023)

Probabilistic benefit-risk analysis of fish: Nutritional benefit versus methylmercury-contaminated risk - Pinpin Lin; Pei-I Lee; Min-Pei Ling (Marine Pollution Bulletin, 2023)

The underappreciated importance of solar radiation in constraining spring phenology of temperate ecosystems in the Northern and Eastern United States - Yating Gu; Yingyi Zhao; Zhengfei Guo; Lin Meng; Kun Zhang; Jing Wang; Calvin K.F. Lee; Jing Xie; Yantian Wang; Zhengbing Yan; He Zhang; Jin Wu (Remote Sensing of Environment, 2023)

The paleo-lithospheric structure and rifting-magmatic processes of the northern South China Sea passive margin - Zhongxian Zhao; Zhen Sun; Ning Qiu; Minghui Zhao; Jiazheng Zhang; Fucheng Li; Jian Lin; Eun Young Lee (Gondwana Research, 2023)

Dietary administration of a postbiotic, heat-killed Pediococcus pentosaceus PP4012 enhances growth performance, immune response and modulates intestinal microbiota of white shrimp, Penaeus vannamei - Rolissa Ballantyne; Jai-Wei Lee; Sz-Tsan Wang; Jin-Seng Lin; Deng-Yu Tseng; Yi-Chu Liao; Hsiao-Tung Chang; Ting-Yu Lee; Chun-Hung Liu (Fish & Shellfish Immunology, 2023)

Sustainable utilization of aging-deteriorated microplastics as triboelectric nanogenerator - Seongeun Cho; Kyunghwan Cha; Banseok Kim; Joonseok Lee; Kyungtae Park; Seh-Hoon Chung; Myunghwan Song; Deokjae Heo; Jin-ho Son; Moonhyun Choi; Zong-Hong Lin; Jinkee Hong; et al. (Chemical Engineering Journal, 2023)

Plant canopies exhibit stronger thermoregulation capability at the seasonal than diurnal timescales - Zhengfei Guo; Kun Zhang; Hua Lin; Bartosz M. Majcher; Calvin K.F. Lee; Christopher J. Still; Jin Wu (Agricultural and Forest Meteorology, 2023)

Implications for biological invasion of non‐native plants for sale in the world's largest online market - Achyut Kumar Banerjee; Tien Ming Lee; Hui Feng; Xinru Liang; Yuting Lin; Jiakai Wang; Minghui Yin; Hao Peng; Yelin Huang (Conservation Biology, 2023)
Internet trade is increasingly recognized as a dispersal pathway of non‐native plant species that is difficult to monitor. We sought to identify non‐native flora present in the Chinese online market, the largest e‐commerce market globally, and to decipher the effect of existing trade regulations, among other variables, on e‐trading patterns and to inform policy. We used a comprehensive list of 811 non‐native plant species in China present in 1 of the 3 phases of the invasion continuum (i.e., introduced, naturalized, and invasive). The price, propagule types, and quantities of the species offered for sale were retrieved from 9 online stores, including 2 of the largest platforms. Over 30% of the non‐native species were offered for sale in the online marketplaces; invasive non‐native species dominated the list (45.53%). No significant price difference was observed across the non‐native species of the 3 invasion categories. Among the 5 propagule types, a significantly higher number of non‐native species were offered for sale as seeds. The regression models and path analyses consistently revealed a direct positive effect of the number of uses and species’ minimum residence time and an indirect effect of biogeography on the pattern of trade in non‐native plant species when minimal phylogenetic signal was detected. A review of the existing phytosanitary regulations in China revealed their inadequacy in managing e‐trading of non‐native plant species. To address the problem, we propose integration of a standardized risk assessment framework that considers perceptions of stakeholders and is adaptable based on continuous surveillance of the trade network. If implemented successfully, the measures could provide a template for other countries to strengthen trading regulations for non‐native plant species and take proactive management measures.

Body composition modify the association between ambient particulate matter and lung function among asthma patients - Fang-Chi Lin; Pei-Shih Chen; Yuan-Chung Lin; Meng-Chih Lin; Chao-Chien Wu; Kang-Shin Chen; Chien-Hung Lee; Tsu-Nai Wang (Environmental Science and Pollution Research, 2023)

Captive Reproductive Behavior, Spawning, and Early Development of White-Barred Goby Amblygobius phalaena (Valenciennes, 1837) and Examined Larval Survival and Viability at Different Water Temperatures and Salinities - Pei-Sheng Chiu; Shine-Wei Ho; Cheng-Hsuan Huang; Yen-Chun Lee; Yu-Hung Lin (Fishes, 2023)
White-barred goby Amblygobius phalaena is a highly valued marine ornamental fish, but its captive reproduction and early life history are poorly understood. In this study, the captive reproductive behavior, early development, and optimal temperature and salinity for the larval survival and viability of A. phalaena were investigated for the first time. Spawning occurred between 11:00 and 13:00, with the breeding pairs naturally spawning 24 times from 1 June 2021 to 30 June 2022. The fecundity ranged from 11,022 to 95,858 eggs per spawning event. Hatching occurred approximately 81 h and 26 min after fertilization at a temperature of 27.0 ± 0.9 °C. Newly hatched larvae had a total length (TL) of 1.91–2.03 mm with 24–26 somites. The larvae transformed into juveniles at 30 days post-hatch. Experiments were conducted at different temperatures (21, 24, 27, 30, and 33 °C) and salinities (18, 24, 30, and 36 ppt) to determine the optimal conditions for larval survival and viability. The results indicate that the most suitable conditions in terms of temperature were in the range of 21–27 °C and 30 ppt for salinity. These findings provide valuable insights for the future development of captive-breeding techniques and the commercial production of other marine ornamental gobies.

Estimating arsenic biotransfer factors from feed to chicken: a viable approach to animal feed risk assessment - Ching-Chi Hung; Hsin-Tang Lin; Ching-Yi Chen; Kuan-Yi Chen; Tsung-Yu Lee; Chow-Feng Chiang (Food Additives & Contaminants: Part A, 2023)

Magnetic anaerobic granular sludge for sequestration and immobilization of Pb - Rui Zhou; Han Li; Chengshuai Liu; Yizhang Liu; Jyh-Fu Lee; Yu-Jung Lin; Zhang Yan; Zhangyi Xu; Xiaoyun Yi; Chunhua Feng (Water Research, 2023)

Corrigendum to: “Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice” J. Hazard. Mater. 430 (2022) 128431 - Chiang-Wen Lee; Lee-Fen Hsu; I.-Lin Wu; Yung-Li Wang; Wei-Chen Chen; Yan-Jun Liu; Lu-Tang Yang; Chong-Lun Tan; Yueh-Hsia Luo; Chia-Ching Wang; Hui-Wen Chiu; Thomas Chung-Kuang Yang; et al. (Journal of Hazardous Materials, 2023)

Cost-effective and accurate monitoring of flowering across multiple tropical tree species over two years with a time series of high-resolution drone imagery and deep learning - Calvin Ka Fai Lee; Guangqin Song; Helene C. Muller-Landau; Shengbiao Wu; S. Joseph Wright; K.C. Cushman; Raquel Fernandes Araujo; Stephanie Bohlman; Yingyi Zhao; Ziyu Lin; Zounachuan Sun; Peter Chuen Yan Cheng; et al. (ISPRS Journal of Photogrammetry and Remote Sensing, 2023)

Evaluation of alternative processes of methanol production from CO2: Design, optimization, control, techno-economic, and environmental analysis - Hsuan-Han Chiou; Chi-Jui Lee; Bo-Sheng Wen; Jian-Xun Lin; Cheng-Liang Chen; Bor-Yih Yu (Fuel, 2023)

Developing sustainable and recyclable high-efficiency electromagnetic interference shielding nanocomposite foams from the upcycling of recycled poly(ethylene terephthalate) - Chia-Wei Lee; Chia-Hsing Lin; Lyu-Ying Wang; Yi-Huan Lee (Chemical Engineering Journal, 2023)

Exposure to silver impairs the osmoregulatory capability of euryhaline medaka (Oryzias latipes) subjected to salinity changes - Jiun-lin Horng; Ya-Shan Lee; Li-Yih Lin (Aquatic Toxicology, 2023)

Highly efficient carbon assimilation and nitrogen/phosphorus removal facilitated by photosynthetic O2 from algal-bacterial aerobic granular sludge under controlled DO/pH operation - Zejiao Li; Jixiang Wang; Jialin Liu; Xingyu Chen; Zhongfang Lei; Tian Yuan; Kazuya Shimizu; Zhenya Zhang; Duu-Jong Lee; Yuemei Lin; Yasuhisa Adachi; Mark C.M. van Loosdrecht (Water Research, 2023)

Co-incidence of BA.1 and BA.2 at the start of Singapore's Omicron wave revealed by Community and University Campus wastewater surveillance - Feng Jun Desmond Chua; Se Yeon Kim; Eric Hill; Jia Wei Cai; Wei Lin Lee; Xiaoqiong Gu; Siti Aisyah Afri Affandi; Wee Chiew Germaine Kwok; Weijie Ng; Mats Leifels; Federica Armas; Franciscus Chandra; et al. (Science of The Total Environment, 2023)

A coupled electrochemical process for schwertmannite recovery from acid mine drainage: Important roles of anodic reactive oxygen species and cathodic alkaline - Ziyuan Huang; Huanxin Ma; Chengshuai Liu; Fangyuan Meng; Jyh-Fu Lee; Yu-Jung Lin; Xiaoyun Yi; Zhi Dang; Chunhua Feng (Journal of Hazardous Materials, 2023)

Can urban polycentricity improve air quality? Evidence from Chinese cities - Will W. Qiang; Haowen Luo; Yuxuan Xiao; David W.H. Wong; Alex S. Shi; Ziwei Lin; Bo Huang; Harry F. Lee (Journal of Cleaner Production, 2023)

Water-soluble propolis extract as a natural preservative for jaboticaba juice - Lee Suan Chua; Yi Lin Chan; Zhi Ying Tay; John Soo (Food Bioscience, 2023)

Long-term DEHP/MEHP exposure promotes colorectal cancer stemness associated with glycosylation alterations - Pei-Chun Shih; Hsin-Pao Chen; Ching-Cheng Hsu; Chung-Hsien Lin; Chou-Yuan Ko; Chao-Wen Hsueh; Cheng-Yi Huang; Tian-Huei Chu; Cheng-Chun Wu; Yu-Cheng Ho; Ngoc Uyen Nhi Nguyen; Shih-Chung Huang; et al. (Environmental Pollution, 2023)

Effect of functionalized nanodiamonds and surfactants mediation on the nanofiltration performance of polyamide thin-film nanocomposite membranes - T.M. Subrahmanya; Jing-Yang Lin; Januar Widakdo; Hannah Faye M. Austria; Owen-Setiawan; Yu-Hsuan Chiao; Tsung-Han Huang; Wei-Song Hung; Hideto Matsuyama; Kueir-Rarn Lee; Juin-Yih Lai (Desalination, 2023)

Implementing a deep-learning model using Google street view to combine social and physical indicators of gentrification - William Thackway; Matthew Ng; Chyi-Lin Lee; Christopher Pettit (Computers, Environment and Urban Systems, 2023)

High entropy promoted active site in layered double hydroxide for ultra-stable oxygen evolution reaction electrocatalyst - Thi Xuyen Nguyen; Chia-Chien Tsai; Van Thanh Nguyen; Yan-Jia Huang; Yen-Hsun Su; Siang-Yun Li; Rui-Kun Xie; Yu-Jung Lin; Jyh-Fu Lee; Jyh-Ming Ting (Chemical Engineering Journal, 2023)

Virtuous utilization of carbon dioxide in pyrolysis of polylactic acid - Seong-Heon Cho; Youkwan Kim; Sangyoon Lee; Kun-Yi Andrew Lin; Wei-Hsin Chen; Sungyup Jung; Doyeon Lee; Deok Hyun Moon; Young Jae Jeon; Eilhann E. Kwon (Chemical Engineering Journal, 2023)

Sulfur-induced electronic optimization of Mo5N6 for hydrogen evolution through topochemical substitution - Jianmei Chen; Xiaochun Liu; Hao Wang; Chao-Lung Chiang; Pengfei Hou; Jianmin Li; Huanyu Jin; Shujuan Liu; Xing Meng; Yan-Gu Lin; Jong-Min Lee; Qiang Zhao (Chemical Engineering Journal, 2023)

Diurnal cycle of precipitation over global monsoon systems in CMIP6 simulations - Cheng Tao; Shaocheng Xie; Shuaiqi Tang; Jiwoo Lee; Hsi-Yen Ma; Chengzhu Zhang; Wuyin Lin (Climate Dynamics, 2023)

Chemical decontamination of foods using non-thermal plasma-activated water - Samuel Herianto; Rachelle D. Arcega; Chih-Yao Hou; How-Ran Chao; Ching-Chang Lee; Chia-Min Lin; Trias Mahmudiono; Hsiu-Ling Chen (Science of The Total Environment, 2023)

Impact of heat on all-cause and cause-specific mortality: A multi-city study in Texas - Chunyu Guo; Kevin Lanza; Dongying Li; Yuyu Zhou; Kristin Aunan; Becky P.Y. Loo; Jason Kai Wei Lee; Bin Luo; Xiaoli Duan; Wangjian Zhang; Zhengjun Zhang; Shao Lin; et al. (Environmental Research, 2023)

Probing air pollution in the Taichung metropolitan area, Taiwan.Part 1: Comprehensive model evaluation and the spatial-temporal evolution of a PM2.5 pollution event - Ming-Tung Chuang; Charles C.-K. Chou; Chuan-Yao Lin; Ja-Huai Lee; Wei-Che Lin; Wei-Nai Chen; Chian-Yi Liu; Chih-Chung Chang (Atmospheric Research, 2023)

The contrast in suspended particle dynamics at surface and near bottom on the river-dominated northern South China Sea shelf in summer: implication on physics and biogeochemistry coupling - Jay Lee; James T. Liu; Yu-Shih Lin; Chen-Tung Arthur Chen; Bo-Shian Wang (Frontiers in Marine Science, 2023)
To understand the process-response relations among physical forcing and biogeochemical properties of suspended particles (SPs) in the river-dominated northern South China Sea shelf, a 5-day shipboard observation was conducted at a fixed location on the dispersal pathway of the Zhujiang (Pearl) River plume (ZRP) in the summer of 2016. Instrumented moorings were deployed near the sampling site to record the flow and wave fields every 10 minutes. Hydrographic properties were measured hourly to identify different water masses. Water and SPs samples at the surface (3 m) and near the bottom (3 m above the bed) were taken every 3 h for the analyses of nutrients, chlorophyll-a (Chl-a), and particulate organic matter (POM including POC, PN, and δ 13 C POC ). Meanwhile, the grain-size composition of SPs and seafloor sediment were also analyzed. Results showed that monsoon winds drove cold upwelling and ZRP waters at the surface. Both the upwelling and ZRP regimes contained newly produced marine phytoplankton based on low POC/Chl-a ratio (PC ratio) and enriched δ 13 C POC. However, SPs in the ZRP regime were smaller (<153 µm), having denser particle bulk density, and less enriched δ 13 C POC , indicating different bio-communities from the upwelling regime. EOF analysis of the surface data suggested that mixing processes and the dispersal of the ZRP regime were mainly controlled by far-field storm winds, tidal modulation, and strength of mixing. On the other hand, a bottom nepheloid layer (BNL) was observed, mainly consisting of SPs<63 μm with higher bulk density than SPs at the surface. POM in the BNL was degraded and δ 13 C POC -depleted according to the PC ratio and δ 13 C POC . EOF analysis of the near-bottom data indicated that the dominant physical processes influencing the biogeochemical properties of SPs in the BNL were jointly the upwelling-associated lateral transport (first order) and tide-related resuspension (second order). Our study identified the contrast between the surface and near-bottom regimes with the coupling patterns among physical forcing and physiochemical properties of SPs using good constraints on particle dynamics and particle sources.

Transition of carbon-nitrogen coupling under different anthropogenic disturbances in subtropical small mountainous rivers - Li-Chin Lee; Gabriele Weigelhofer; Thomas Hein; Shin-Chien Chan; Ying-San Liou; Chien-Sen Liao; Fuh-Kwo Shiah; Yu-Lin Yu; Tsung-Yu Lee; Jr-Chuan Huang (Science of The Total Environment, 2023)

Meeting the heavy-metal safety requirements for food crops by using biochar: An investigation using sunflower as a representative plant under different atmospheric CO2 concentrations - Yiying Wang; Guiying Lin; Xian Li; Ming Hang Tai; Shuang Song; Hugh Tiang Wah Tan; Ken Leong; Elvis Yew Boon Yip; Grace Yoke Chin Lee; Yanjun Dai; Chi-Hwa Wang (Science of The Total Environment, 2023)

Time to reconsider the enigmatic tail of eastern Paleo-Tethys: New insights from Borneo - Xiao Ran Zhang; Sun-Lin Chung; Azman A. Ghani; Rezal Rahmat; Yi-Ju Hsin; Hao-Yang Lee; Ping-Ping Liu; Jinyu Xi (Lithos, 2023)

Neurite growth induced by red light-caused intracellular reactive oxygen species production through cytochrome c oxidase activation - Yu-Chiu Kao; Guan-Yun Lin; Ji-Yen Cheng; Chau-Hwang Lee (Journal of Photochemistry and Photobiology B: Biology, 2023)

Electrospun fluorinated carbon nanotubes/silk fibroin composite nanofibers for the analysis of perfluoroalkyl and polyfluoroalkyl substances - Zhenzhen Huang; Peng Liu; Huijun Chen; Xia Lin; Yan Zhou; Yudong Xing; Hian Kee Lee (Journal of Hazardous Materials, 2023)

Disturbance region update method with preconditioning for steady compressible and incompressible flows - Hongyuan Lin; Chongwen Jiang; Shuyao Hu; Zhenxun Gao; Chun-Hian Lee (Computer Physics Communications, 2023)

Ni-B-P micro spheres for superior water splitting OER electrocatalyst satisfying industrial operational requirement - Md Ahasan Habib; Rutuja Mandavkar; Shusen Lin; Shalmali Burse; Tasmia Khalid; Mehedi Hasan Joni; Jae-Hun Jeong; Jihoon Lee (Chemical Engineering Journal, 2023)

Photoinduced transformation of ferrihydrite in the presence of aqueous sulfite and its influence on the repartitioning of Cd - Jinwen Qiu; Xiaokang Hou; Yuan Ren; Chengshuai Liu; Fangyuan Meng; Jyh-Fu Lee; Yu-Jung Lin; Ziyuan Huang; Huanxin Ma; Zhenqing Shi; Chunhua Feng (Water Research, 2023)

Using HRMS fingerprinting to explore micropollutant contamination in soil and vegetables caused by swine wastewater irrigation - Wen-Ling Chen; Sih-Yi Yu; Shu-Yen Liu; Sheng-Chi Lin; Tsung-Han Lee (Science of The Total Environment, 2023)

Tectonic evolution of the neoproterozoic tusham ring complex, Northwestern India: Constraints from geochemistry and zircon U Pb geochronology, and implications for Rodinia supercontinent history - A. Krishnakanta Singh; Naveen Kumar; Sun-Lin Chung; Hao-Yang Lee; M. Santosh; Radhika Sharma; Naresh Kumar; R.K. Bikramaditya; Govind Oinam; Nongmaithem Lakhan (Lithos, 2023)

Wastewater surveillance of SARS-CoV-2 and chemical markers in campus dormitories in an evolving COVID − 19 pandemic - Sanjeeb Mohapatra; Sumedha Bhatia; Kavindra Yohan Kuhatheva Senaratna; Mui-Choo Jong; Chun Min Benjamin Lim; G.Reuben Gangesh; Jia Xiong Lee; Goh Shin Giek; Callie Cheung; Lin Yutao; You Luhua; Ng How Yong; et al. (Journal of Hazardous Materials, 2023)

Removal and concurrent reduction of Cr(VI) by thermoacidophilic Cyanidiales: a novel extreme biomaterial enlightened for acidic and neutral conditions - Yen-Lin Cho; Yu-Min Tzou; Chun-Chieh Wang; Yao-Chang Lee; Liang-Ching Hsu; Shao-Lun Liu; Afifah Assakinah; Yu-Hsien Chen; Nhu Anh Thi Than; Yu-Ting Liu; Jörg Rinklebe (Journal of Hazardous Materials, 2023)

Sea Urchin Removal and Effectiveness Evaluation from the Long-Term Monitoring Data in Dokdo, Korea - Su-Young Jeong; Sungtae Kim; Chae-Lin Lee; Gyusang Kang; Jungsoo Kim; Chang-Soo Kim; Seokjin Yoon; Kangseok Hwang; Jae-Won Yoo (Ocean Science Journal, 2023)

Challenges to govern a global sustainability science problem: Lessons from a domestic climate change research project - Shih-Yun Kuo; Tsung-Ta Tang; Huang-Hsiung Hsu; Lee-Yaw Lin; Yung-Ming Chen (Environment, Development and Sustainability, 2023)

Meta-analysis of studies on protection provided by different prophylactic agents, their routes of administration and incubation times against nodavirus infection in Macrobrachium rosenbergii - Ken Fong Chen; Sathiya Maran; Wen Siang Tan; Lin Kooi Ong; Syafiq Asnawi Zainal Abidin; Iekhsan Othman; Beng Ti Tey; Ronald Fook Seng Lee (Aquaculture, 2023)

Investigating the evolution of the Guangdong-Hong Kong-Macao Greater Bay Area (GBA) multi-port system: The multi-faced perspectives - Yu Fu; Qin Lin; Manel Grifoll; Jasmine Siu Lee Lam; Hongxiang Feng (Ocean & Coastal Management, 2023)

Chlorpyrifos induces neuronal cell death via both oxidative stress and Akt activation downstream-regulated CHOP-triggered apoptotic pathways - Jhe-Wei Lin; Shih-Chang Fu; Jui-Ming Liu; Shing-Hwa Liu; Kuan-I Lee; Kai-Min Fang; Ren-Jun Hsu; Chun-Fa Huang; Kun-Min Liu; Kai-Chih Chang; Chin-Chuan Su; Ya-Wen Chen (Toxicology in Vitro, 2023)

Ambient relative humidity-dependent obstructive sleep apnea severity in cold season: A case-control study - Kuan-Jen Bai; Wen-Te Liu; Yuan-Chien Lin; Yansu He; Yueh-Lun Lee; Dean Wu; Ta-Yuan Chang; Li-Te Chang; Chun-Yeh Lai; Cheng-Yu Tsai; Kian Fan Chung; Kin-Fai Ho; et al. (Science of The Total Environment, 2023)

Dynamic life cycle assessment for water treatment implications - Huan-Yu Shiu; Mengshan Lee; Zih-Ee Lin; Pei-Te Chiueh (Science of The Total Environment, 2023)

Upcycling textile waste using pyrolysis process - Hee Sue Lee; Sungyup Jung; Kun-Yi Andrew Lin; Eilhann E. Kwon; Jechan Lee (Science of The Total Environment, 2023)

Cyclic simple shear behavior of a tropical alluvial soil - Alsidqi Hasan; Nisa binti Ismail; Yieng Yung Chuo; Lin Jye Lee (Physics and Chemistry of the Earth, Parts A/B/C, 2023)

InSAR-based investigation on spatiotemporal characteristics of river sediment behavior - Shih-Yuan Lin; Shih-Teng Chang; Ching-Fang Lee (Journal of Hydrology, 2023)

Modeling of an integrated H2S/NH3 scrubber and regeneration columns for coke oven gas purification - Hao-Jen Pan; Ming-Chun Fang; Jeffrey D. Ward; Hao-Yeh Lee; Hsun-Yu Lin; Cheng-Ting Hsieh; Chih-Lung Lee; Tzu-Hsien Huang; Yu-Chen Hsieh; Shih-Chieh Lin; Wei-Ti Chou (Journal of Cleaner Production, 2023)

Development of polyethylenimine-functionalized cellulose fibers for recovery of Au(0) from Au(III)-containing acidic solutions through an adsorption–reduction–detachment–aggregation mechanism - Xiaoyu Lin; Myung-Hee Song; Duy Tho Tran; Youn-Sik Lee; Yeoung-Sang Yun (Journal of Cleaner Production, 2023)

Catalytic removal of 2-butanone with ozone over porous spent fluid catalytic cracking catalyst - Yujin Hwang; Young-Min Kim; Jung Eun Lee; Gwang Hoon Rhee; Pau-Loke Show; Kun-Yi Andrew Lin; Young-Kwon Park (Environmental Research, 2023)

Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis - Wen-Chih Liu; Hui-Wen Chiu; Chu-Lin Chou; Yu-Jhe Chiu; Yu-Hsuan Lee (Environmental Pollution, 2023)

Facile synthesis of spiro-core-based hole-transporting material for high-performance and stable perovskite solar cells - Kun-Mu Lee; Seid Yimer Abate; June Hung Yang; Wei-Hao Chiu; Seoungjun Ahn; Sie-Rong Li; Kang-Ling Liau; Yu-Tai Tao; Yan-Duo Lin (Chemical Engineering Journal, 2023)

Human platelet mitochondria improve the mitochondrial and cardiac function of donor heart - Zhi Jun Lin; Soomin Kim; Hui Xing Cui; Kyuboem Han; Hong Kyu Lee; Chun-Hyung Kim; Young Cheol Kang; Yin Hua Zhang (Pflügers Archiv - European Journal of Physiology, 2023)

Analyzing landslide-induced debris flow and flow-bridge interaction by using a hybrid model of depth-averaged model and discrete element method - Wen-Jie Shiu; Ching-Fang Lee; Chia-Chi Chiu; Meng-Chia Weng; Che-Ming Yang; Wei-An Chao; Chun-Yuan Liu; Cheng-Han Lin; Wei-Kai Huang (Landslides, 2023)

Automatic diagnosis of late-life depression by 3D convolutional neural networks and cross-sample Entropy analysis from resting-state fMRI - Chemin Lin; Shwu-Hua Lee; Chih-Mao Huang; Guan-Yen Chen; Wei Chang; Ho-Ling Liu; Shu-Hang Ng; Tatia Mei-Chun Lee; Shun-Chi Wu (Brain Imaging and Behavior, 2023)
Resting-state fMRI has been widely used in investigating the pathophysiology of late-life depression (LLD). Unlike the conventional linear approach, cross-sample entropy (CSE) analysis shows the nonlinear property in fMRI signals between brain regions. Moreover, recent advances in deep learning, such as convolutional neural networks (CNNs), provide a timely application for understanding LLD. Accurate and prompt diagnosis is essential in LLD; hence, this study aimed to combine CNN and CSE analysis to discriminate LLD patients and non-depressed comparison older adults based on brain resting-state fMRI signals. Seventy-seven older adults, including 49 patients and 28 comparison older adults, were included for fMRI scans. Three-dimensional CSEs with volumes corresponding to 90 seed regions of interest of each participant were developed and fed into models for disease classification and depression severity prediction. We obtained a diagnostic accuracy > 85% in the superior frontal gyrus (left dorsolateral and right orbital parts), left insula, and right middle occipital gyrus. With a mean root-mean-square error (RMSE) of 2.41, three separate models were required to predict depressive symptoms in the severe, moderate, and mild depression groups. The CSE volumes in the left inferior parietal lobule, left parahippocampal gyrus, and left postcentral gyrus performed best in each respective model. Combined complexity analysis and deep learning algorithms can classify patients with LLD from comparison older adults and predict symptom severity based on fMRI data. Such application can be utilized in precision medicine for disease detection and symptom monitoring in LLD.

Impacts of 2 and 4°C global warmings on extreme temperatures in Taiwan - I‐Chun Tsai; Pei‐Rong Hsieh; Chao‐Tzuen Cheng; Yu‐Shiang Tung; Lee‐Yaw Lin; Huang‐Hsiung Hsu (International Journal of Climatology, 2023)
Extreme temperatures were considered natural hazards because they could increase morbidity and mortality. Understanding the extreme temperature changes at different warming levels is crucial to climate change mitigation and adoption for human health. This study projected climate change effects on the intensity, occurrence, and duration of extreme temperatures in Taiwan with 2 and 4°C global warming scenarios using the Weather Research and Forecasting model. The future climate simulations were conducted with the pseudo‐global warming approach, and the future climate changes were obtained from the ensemble mean of simulations in the Coupled Model Intercomparison Project 5. The simulated daily mean temperature increased by 1.40 and 3.09°C under 2 and 4°C global warmings. In a warming world, the daily maximum temperature was projected to increase by 1.35–3.00°C, whereas the daily minimum temperature was even higher, leading to weaker diurnal temperature variation in most regions. The simulation results show that intensified heatwaves with frequent and prolonged durations become par for the course, whereas extremely cold days disappear gradually. The occurrence of heatwaves in the future is projected to be five times that in the current climate. Comparing the global warming impacts over different land‐use types, the heatwave occurrence over urban areas rose more quickly than over other land‐use types; forests are less vulnerable to global warming. On the contrary, the changes in extremely cold days over urban areas were weaker than over other land‐use types. Overall, the effects of global warming on temperature revealed that extreme events were more severe with increased temperature than with the mean state of air temperature. Nonlinear behaviours indicated that global warming should be limited to 2°C, and the additional 2°C warming (from 2 to 4°C) should be addressed carefully.

Do ectoparasites on fish gills “talk” with gut microbiota far away? - Lin Wang; Defeng Zhang; Jun Xie; Ouqin Chang; Qing Wang; Cunbin Shi; Fei Zhao; Hua Gong; Yan Ren; Najiah Musa; Kok Leong Lee; Houjun Pan (Aquaculture, 2023)

Transmission of antibiotic resistance genes through mobile genetic elements in Acinetobacter baumannii and gene-transfer prevention - Jeong Ho Jeon; Kyung-Min Jang; Jung Hun Lee; Lin-Woo Kang; Sang Hee Lee (Science of The Total Environment, 2023)

Constant-temperature predictions underestimate growth of a fungal amphibian pathogen under individual host thermal profiles - Sasha E. Greenspan; Elizabeth A. Roznik; Lexie Edwards; Richard Duffy; Lee Berger; Deborah S. Bower; David A. Pike; Lin Schwarzkopf; Ross A. Alford (Journal of Thermal Biology, 2023)

Comparison of polycyclic aromatic hydrocarbon accumulation in crab tissues with the ambient marine particles from shallow hydrothermal vents, northeast Taiwan - Fang-Jing Deborah Lee; Jiang-Shiou Hwang; Jing-O Cheng; Huei-Ting Lin; Fung-Chi Ko (Environmental Research, 2023)

A low-cost eco-friendly fast drug extraction (FaDEx) technique for environmental and bio-monitoring of psychoactive drug in urban water and sports-persons’ urine samples - Swapnil Gurrani; Karthikeyan Prakasham; Jess Lim Zii Ying; Jentaie Shiea; Yi-Jia Ku; Yu-Chia Lin; Po-Chin Huang; Gangadhar Andaluri; Kung-Che Lee; Vinoth Kumar Ponnusamy (Environmental Research, 2023)

Sustainable approaches on industrial food wastes to value-added products – A review on extraction methods, characterizations, and its biomedical applications - Arul Jayanthi Antonisamy; Sivasankari Marimuthu; Sankar Malayandi; Karthikeyan Rajendran; Yuan-Chung Lin; Gangadhar Andaluri; Siew Ling Lee; Vinoth Kumar Ponnusamy (Environmental Research, 2023)

Identification of serum metabolic signatures of environmental-leveled phthalate in the Taiwanese child population using NMR-based metabolomics - Sheng-Han Lee; Zhi-Yi Du; Wei-Chen Tseng; Wan-Yu Lin; Mei-Huei Chen; Ching-Chun Lin; Hao-Jan Liang; Hui-Ju Wen; Yue-Leon Guo; Pau-Chung Chen; Ching-Yu Lin (Environmental Pollution, 2023)

13.2% EQE near-infrared TADF OLED with emission peak at 761 nm - Jing-Wen Tai; Yukun Tang; Kai Zhang; Chen-Zong Yang; Ze-Hui Pan; Yu-Ching Lin; Yu-Wei Shih; Chia-Hsun Chen; Tien-Lung Chiu; Jiun-Haw Lee; Chuan-Kui Wang; Chung-Chih Wu; et al. (Chemical Engineering Journal, 2023)

Free-standing vertically aligned tin disulfide nanosheets for ultrasensitive aptasensor design toward Alzheimer’s diagnosis applications - Bayu Tri Murti; Yi-June Huang; Athika Darumas Putri; Chuan-Pei Lee; Chien-Ming Hsieh; Shih-Min Wei; Meng-Lin Tsai; Chih-Wei Peng; Po-Kang Yang (Chemical Engineering Journal, 2023)

Hybrid renewable energy systems involving thermochemical conversion process for waste-to-energy strategy - Jechan Lee; Kun-Yi Andrew Lin; Sungyup Jung; Eilhann E. Kwon (Chemical Engineering Journal, 2023)

Clustered regularly interspaced short palindromic repeats (CRISPR) technology and genetic engineering strategies for microalgae towards carbon neutrality: A critical review - Tse-Min Lee; Jia-Yi Lin; Tsung-Han Tsai; Ru-Yin Yang; I-Son Ng (Bioresource Technology, 2023)

Advanced biological technologies for removal and recovery of reactive nitrogen (Nr) from wastewaters - Bin-Le Lin; Duu-Jong Lee; Giorgio Mannina; Wenshan Guo (Bioresource Technology, 2023)

Conducting an adaptive evaluation framework of importance and performance for community-based earthquake disaster management - Bih-Chuan Lin; Chun-Hung Lee (Natural Hazards, 2023)
The frequency and intensity of natural disasters have been increasing in recent decades; especially earthquakes are one of the causes of major natural disasters. Improving community adaptive response to disasters based on community capacity has gradually become an effective means of coping with disaster risks, as well as improving residents' well-being and community participation in disaster planning and management. We integrate community resilience and disaster management to establish an evaluation framework for community-based earthquake disaster management (CEDM) based on community perspectives under importance performance analysis method, and identify the factors affecting community adaptive behavior. Features that affect the differentiation of community residents' adaptive behavior in CEDM program are classified into risk perception, learning earthquake knowledge, the ability on earthquake prevention, and creating a platform on CEDM. The results identify that the CEDM has to integrate the higher community education plan, the stronger flexible to disaster preparedness, the higher the residents' awareness of disaster prevention, the stronger the ability to adapt to disasters; the higher the ability of the government and non-profit organizations to cooperate with the community to deal with disasters, and the stronger the community's ability to manage disasters. These findings provide valuable insights into the construction of CEDM systems and related policymaking.

Facile fabrication of a 2D/2D CoFe-LDH/g-C3N4 nanocomposite with enhanced photocatalytic tetracycline degradation - Mengxue Li; Mengmeng Chen; Stephanie Ling Jie Lee; Sijie Lin (Environmental Science and Pollution Research, 2023)

Promoting human rights for Taiwan’s fishermen: Collaboration with the primary source countries of Taiwan’s DWF migrant fishermen - Po-Chih Hung; Hsiao-Chien Lee; Chih-Cheng Lin; Wen-Hong Liu (Frontiers in Marine Science, 2022)
Taiwan is one of the largest distant water fishing (DWF) nations worldwide, and relies largely on the migrant labor to keep costs low. However, this industry has caused Taiwan to be listed in the 2020 “List of Goods Produced by Child Labor or Forced Labor” of the U.S. Department of Labor. In view of this, the Taiwanese government is actively adopting further management measures to supervise the domestic and foreign fishermen agencies. It is because the latter has been involved in many disputes, especially in recruitment, payroll, and labor contracts, which directly or indirectly affect the rights of migrant fishermen. On the other hand, although the C188 Work in Fishing Convention has stregthend the protection of the fishermen’s human rights, it still stays ambiguous in terms of private agency management. That is also why so many disputes have been caused in recent years.This study conducts a comparative analysis of the agency management systems in the primary source countries of Taiwan’s distant water fishing migrant fishermen (that is, Indonesia, the Philippines, and Vietnam), as well as interviews with distant water fishing stakeholders to provide insights on the improvement of agency management and migrant fishermen’s rights in Taiwan. The findings imply that the positive interaction, mutual trust, and understanding of laws and regulations between fishermen’s exporting and importing countries lead to future cross-national collaboration. This study suggests that the Taiwanese government should follow the spirit of the C188 but not be restricted to the Convention texts to amend or formulate regulations and policies of agencies for fully protecting the rights of migrant fishermen.

Associations between residential proximity to agricultural land use as pesticides exposure and birth outcomes - Kuna-Chun Chen; Shuo-Fang Lee; Shyang-Woei Lin; Jia-Shan Xie; Yu‐Hsun Chang; Lih-Ming Yiin; Chia-Jung Hsieh (Environmental Science and Pollution Research, 2022)

Application and Validation of an Ecological Quality Index, ISEP, in the Yellow Sea - Jae-Won Yoo; Yong-Woo Lee; Mi-Ra Park; Chang-Soo Kim; Sungtae Kim; Chae-Lin Lee; Su-Young Jeong; Dhongil Lim; Sung-Yong Oh (Journal of Marine Science and Engineering, 2022)
An ecological index of macrobenthic communities is an important tool for assessing the biological quality of habitats and ecosystems. We tested the performance of the inverse function of the Shannon–Wiener evenness proportion (ISEP) with data from the entire west coast of Korea, seasonally sampled from 2006 to 2008. Two validations were performed: (1) examination of the relationship between ISEP and environmental factors and (2) correspondence between the ISEP and the Pearson–Rosenberg (P-R) model for the species-abundance-biomass (SAB) patterns and taxonomical variations. The ISEP was significantly correlated with suspended solids but independent of other natural habitat conditions due to their low to moderate contamination levels. From this, ISEP performed as expected in transitional zones of low salinity and applications across habitats of various sediments. The SAB patterns and taxonomic variations along the ISEP grades showed marked similarities to the P-R model. The only departure was biomass, which increased after the normal status. The increase was interpreted as reflecting a healthier and more mature status. Taxonomic variation patterns and the taxa composition that characterized either poor or healthy status corresponded well with the P-R model. The conformity to the P-R model indicates the capability and potential applicability of the ISEP to other coastal systems.

Indigodole E from Strobilanthes cusia exhibits anti-IL-17A effect - Chia-Lin Lee; Chien-Ming Wang; Hung-Rong Yen; Ying-Chyi Song; Chao-Jung Chen (Natural Product Research, 2022)

Breast cancer incidence in a national cohort of female workers exposed to special health hazards in Taiwan: a retrospective case-cohort study of ~ 300,000 occupational records spanning 20 years - Yun-Shiuan Chuang; Chun-Ying Lee; Pei-Chen Lin; Chih-Hong Pan; Hui-Min Hsieh; Chia-Fang Wu; Ming-Tsang Wu (International Archives of Occupational and Environmental Health, 2022)

Enhanced visible light-driven photodegradation of tetracycline by salicylic acid-modified graphitic carbon nitride and toxicity assessment - Mengmeng Chen; Mengxue Li; Peng Li; Stephanie Ling Jie Lee; Juanjuan Tang; Qian Li; Sijie Lin (Environmental Science and Pollution Research, 2022)

Fifty-year change in air pollution in Kaohsiung, Taiwan - Chiu-Hsuan Lee; Peter Brimblecombe; Chon-Lin Lee (Environmental Science and Pollution Research, 2022)
The change in air quality in cities can be the product of regulation and emissions. Regulations require enforcement of emission reduction, but it is often shifting economic and societal structures that influence pollutant emissions. This study examines the long-term record of air pollutants in Kaohsiung, where post-war industrialisation increased pollution substantially, although improvements are observed in recent decades as the city moved to a more mixed economy. The study tracks both gases and particles across a period of significant change in pollution sources in the city. Concentrations of SO 2 and aerosol SO 4 2− were especially high ~1970, but these gradually declined, although SO 4 2− to a lesser extent than its precursor, SO 2 . While twenty-first century emissions of SO 2 and NO x have declined, this has been less so for NH 3 , because it arises from predominantly agricultural sources. The atmosphere in Kaohsiung continues to have high concentrations of O 3 , and these have risen in the city, likely a product of less titration by NO. The changes have meant that ozone has become an increasing threat to health and agriculture. Despite a potential for producing (NH 4 ) 2 SO 4 and NH 4 NO 3 aerosols, a product of a relatively constant supply of NH 3 , visibility has improved in recent years. Emissions of SO 2 and NO x should continue to be reduced, as these strongly affect the amount of fine secondary aerosol. However, the key problem may be ozone, which is difficult to control as it requires careful consideration of the balance of NO x and hydrocarbons so important to its production.

A study of peatland-derived dissolved organic matter from headstream to sea using multiple analytical tools - François L. L. Muller; Kuei-Chen Chang; Yu-Chieh Wang; Chon-Lin Lee (Environmental Science and Pollution Research, 2022)

Correction to: Breeding for disease resistance in soybean: a global perspective - Feng Lin; Sushil Satish Chhapekar; Caio Canella Vieira; Marcos Paulo Da Silva; Alejandro Rojas; Dongho Lee; Nianxi Liu; Esteban Mariano Pardo; Yi-Chen Lee; Zhimin Dong; Jose Baldin Pinheiro; Leonardo Daniel Ploper; et al. (Theoretical and Applied Genetics, 2022)

Breeding for disease resistance in soybean: a global perspective - Feng Lin; Sushil Satish Chhapekar; Caio Canella Vieira; Marcos Paulo Da Silva; Alejandro Rojas; Dongho Lee; Nianxi Liu; Esteban Mariano Pardo; Yi-Chen Lee; Zhimin Dong; Jose Baldin Pinheiro; Leonardo Daniel Ploper; et al. (Theoretical and Applied Genetics, 2022)
Key message This review provides a comprehensive atlas of QTLs, genes, and alleles conferring resistance to 28 important diseases in all major soybean production regions in the world. Abstract Breeding disease-resistant soybean [ Glycine max (L.) Merr.] varieties is a common goal for soybean breeding programs to ensure the sustainability and growth of soybean production worldwide. However, due to global climate change, soybean breeders are facing strong challenges to defeat diseases. Marker-assisted selection and genomic selection have been demonstrated to be successful methods in quickly integrating vertical resistance or horizontal resistance into improved soybean varieties, where vertical resistance refers to R genes and major effect QTLs, and horizontal resistance is a combination of major and minor effect genes or QTLs. This review summarized more than 800 resistant loci/alleles and their tightly linked markers for 28 soybean diseases worldwide, caused by nematodes, oomycetes, fungi, bacteria, and viruses. The major breakthroughs in the discovery of disease resistance gene atlas of soybean were also emphasized which include: (1) identification and characterization of vertical resistance genes reside rhg1 and Rhg4 for soybean cyst nematode, and exploration of the underlying regulation mechanisms through copy number variation and (2) map-based cloning and characterization of Rps11 conferring resistance to 80% isolates of Phytophthora sojae across the USA. In this review, we also highlight the validated QTLs in overlapping genomic regions from at least two studies and applied a consistent naming nomenclature for these QTLs. Our review provides a comprehensive summary of important resistant genes/QTLs and can be used as a toolbox for soybean improvement. Finally, the summarized genetic knowledge sheds light on future directions of accelerated soybean breeding and translational genomics studies.

Prediction of black carbon in marine engines and correlation analysis of model characteristics based on multiple machine learning algorithms - Ying Sun; Lin Lü; Yun-kai Cai; Peng Lee (Environmental Science and Pollution Research, 2022)

Plasma Matrix Metalloproeteinase-9 Is Associated with Seizure and Angioarchitecture Changes in Brain Arteriovenous Malformations - Yo-Tsen Liu; Cheng-Chia Lee; Chun-Fu Lin; Hsiu-Mei Wu; Wan-Yuo Guo; Huai-Che Yang; Feng-Chi Chang; Kang-Du Liou; Chung-Jung Lin (Molecular Neurobiology, 2022)

Predicting Lumbar Vertebral Osteopenia Using LvOPI Scores and Logistic Regression Models in an Exploratory Study of Premenopausal Taiwanese Women - Chun-Wen Chen; Yi-Jui Liu; Shao-Chieh Lin; Chien-Yuan Wang; Wu-Chung Shen; Der-Yang Cho; Tung-Yang Lee; Cheng-Hsuan Juan; Cheng-En Juan; Kai-Yuan Cheng; Chun-Jung Juan (Journal of Medical and Biological Engineering, 2022)
Purpose To propose hybrid predicting models integrating clinical and magnetic resonance imaging (MRI) features to diagnose lumbar vertebral osteopenia (LvOPI) in premenopausal women. Methods This prospective study enrolled 101 Taiwanese women, including 53 before and 48 women after menopause. Clinical information, including age, body height, body weight and body mass index (BMI), were recorded. Bone mineral density (BMD) was measured by the dual-energy X-ray absorptiometry. Lumbar vertebral fat fraction (LvFF) was measured by MRI. LvOPI scores (LvOPISs) comprising different clinical features and LvFF were constructed to diagnose LvOPI. Statistical analyses included normality tests, linear regression analyses, logistic regression analyses, group comparisons, and diagnostic performance. A P value less than 0.05 was considered as statistically significant. Results The post-menopausal women had higher age, body weight, BMI, LvFF and lower BMD than the pre-menopausal women (all P < 0.05). The lumbar vertebral osteoporosis group had significantly higher age, longer MMI, and higher LvFF than the LvOPI group (all P < 0.05) and normal group (all P < 0.005). LvOPISs (AUC, 0.843 to 0.864) outperformed body weight (0.747; P = 0.0566), BMI (0.737; P < 0.05), age (0.649; P < 0.05), and body height (0.5; P < 0.05) in diagnosing LvOPI in the premenopausal women. Hybrid predicting models using logistic regression analysis (0.894 to 0.9) further outperformed all single predictors in diagnosing LvOPI in the premenopausal women ( P < 0.05). Conclusion The diagnostic accuracy of the LvOPI can be improved by using our proposed hybrid predicting models in Taiwanese premenopausal women.

Theranostic Radiolabeled Nanomaterials for Molecular Imaging and potential Immunomodulation Effects - Chao-Cheng Chen; Yang-Hsiang Chan; Syue-Liang Lin; Huihua Kenny Chiang; Yi-Jang Lee; Hui-Yen Chuang (Journal of Medical and Biological Engineering, 2022)

How to improve the problem of hotel manpower shortage in the COVID-19 epidemic environment? Exploring the effectiveness of the hotel practice training system - Bing-Wang Xue; Hsiao-Hsien Lin; Chao-Chien Chen; Peng-Yeh Lee; Chin-Hsien Hsu (Environmental Science and Pollution Research, 2022)

Effects of fuel injection system and exhaust gas catalytic treatments on PAH emissions from motorcycles - Sheng-Lun Lin; Hongjie Zhang; Lin-Chi Wang; Yen-Yi Lee; Chien-Er Huang (Environmental Science and Pollution Research, 2022)

Stochastic analysis of the variability of groundwater flow fields in heterogeneous confined aquifers of variable thickness - Ching-Min Chang; Chuen-Fa Ni; We-Ci Li; Chi-Ping Lin; I-Hsian Lee (Stochastic Environmental Research and Risk Assessment, 2022)

Towards less invasive molecular diagnostics for endometrial cancer: massively parallel sequencing of endometrial lavage specimens in women attending for an office hysteroscopy - Angel Chao; Kai-Yun Wu; Chiao-Yun Lin; Yun-Shien Lee; Huei-Jean Huang; Yun-Hsin Tang; Cindy Hsuan Weng; An-Shine Chao; Ting-Chang Chang; Chyong-Huey Lai; Ren-Chin Wu (Journal of Molecular Medicine, 2022)

Vibrio salinus sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll in the western Pacific Ocean - Wei-Sheng Huang; Li-Ting Wang; Jwo-Sheng Chen; Yen-Ting Chen; Sean Ting-Shyang Wei; Yin-Ru Chiang; Pei-Ling Wang; Tzong-Huei Lee; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2022)

An Analytical Solution of Transient Wave Generation in the Wave Channel - Cheng-Tsung Chen; Jaw-Fang Lee; Kuei-Ting Lin; Pi-Sheng Hu (Journal of Marine Science and Engineering, 2022)
Transient characteristics of wave generation in the wave channel can provide unique and important information in contrast to the steady and periodic motion of propagation waves. In this paper, a new analytical solution is proposed for a transient wavemaker problem in the wave channel. The mathematical model of the wavemaker problem is established based on the linear potential wave theory, and a new analytical solution for the corresponding initial and boundary-value problem is presented. The present solution methodology is motivated and developed from old methods shown in literature. The present solution can be mathematically reformulated and shown to be identical to the previous solution using different solution methodology. The present analytical solution is further compared with numerical results and experiments to validate the mathematical model. The present solution is used to calculate the steady state generated wave forms that compare very well with the steady wave theory both in wave length and wave period. The present solution is also used to study unsteady characteristics of wave heights and wave lengths of the leading waves. The present analytical solution methodology can provide an easier approach to obtain the analytical solution for transient wave generation problem in the wave channel.

An unknown component of a well-known population: socio-demographic parameters of Indo-Pacific humpback dolphins (Sousa chinensis) at the western reaches of the Pearl River Delta region - Stephen C. Y. Chan; Leszek Karczmarski; Wenzhi Lin; Ruiqiang Zheng; Yuen-Wa Ho; Lang Guo; Yaqian Mo; Andy T. L. Lee; Carmen K. M. Or; Yuping Wu (Mammalian Biology, 2022)

A multi-isotope analysis on human and pig tooth enamel from prehistoric Sichuan, China, and its archaeological implications - Kuei-chen Lin; Cheng-Yi Lee; Pei-Ling Wang (Archaeological and Anthropological Sciences, 2022)

Registered clinical trials investigating treatment of long COVID: a scoping review and recommendations for research - Felicia Ceban; Alexia Leber; Muhammad Youshay Jawad; Mathew Yu; Leanna M. W. Lui; Mehala Subramaniapillai; Joshua D. Di Vincenzo; Hartej Gill; Nelson B. Rodrigues; Bing Cao; Yena Lee; Kangguang Lin; et al. (Infectious Diseases, 2022)

A Brief Educational Intervention to Increase ED Initiation of Buprenorphine for Opioid Use Disorder (OUD) - Utsha G. Khatri; Kathleen Lee; Theodore Lin; Joseph L. D’Orazio; Mitesh S. Patel; Frances S. Shofer; Jeanmarie Perrone (Journal of Medical Toxicology, 2022)

Factors associated with changes in exercise behaviors during the COVID-19 pandemic - Caroline Himbert; Cassandra A. Hathaway; Bailee Daniels; Karen Salas; Anjelica Ashworth; Biljana Gigic; Tengda Lin; Richard Viskochil; Anne C. Kirchhoff; Douglas Grossman; Jennifer Ose; Jonathan Tward; et al. (Cancer Causes & Control, 2022)

High Levels of 25-OH-Vitamin D and Copper in Pregnant Women with Abnormal Glucose Challenge Test - Chien-Hua Chiang; Wan-Ju Kung; Chien-Hung Lee; Yeong-Hwa Zen; Cheng-Fa Lee; Hui-Ru Yang; Ching-Chiang Lin; Yeou-Lih Huang (Biological Trace Element Research, 2022)

Streptococcus vulneris sp. nov., isolated from wound of patient with diabetic foot ulcer (DFU) - Jen-hao Chung; Li-Ting Wang; Yi-Sheng Chen; Yun-Shien Lee; Shih-Ting Lin; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Jui-hsiang Li (Archives of Microbiology, 2022)

Characterization of chemical constituents with their antioxidant and anti-melanogenesis activities from the roots of Ampelopsis japonica - Chia-Lin Lee; Yun-Lian Jhan; Hsiu-Mei Chiang; Yi-Hung Chen; Chao-Jung Chen; Yuan-Shiun Chang (Natural Product Research, 2022)

Perfusion Defects and Collateral Flow Patterns in Acute Small Subcortical Infarction: a 4D Dynamic MRI Study - Yen-Chu Huang; Jiann-Der Lee; Yi-Ting Pan; Hsu-Huei Weng; Jen-Tsung Yang; Leng-Chieh Lin; Yuan-Hsiung Tsai (Translational Stroke Research, 2022)
The hemodynamic changes of acute small subcortical infarction (SSI) are not well understood. We evaluate the hemodynamic changes and collaterals in acute SSI using perfusion magnetic resonance imaging (MRI). A total of 103 patients with acute SSI in penetrating artery territories were recruited and underwent MRI within 24 h of stroke onset. Using 4D dynamic perfusion MRI, they were divided into three patterns: 25 (24%) with normal perfusion, 31 (30%) with compensated perfusion, and 47 (46%) with hypoperfusion. The development of anterograde or retrograde collaterals was also evaluated. Patients with hypoperfusion pattern had the highest rate of early neurological deterioration (32%, p = 0.007), the largest initial and final infarction volumes ( p < 0.001 and p = 0.029), the lowest relative cerebral blood flow (0.63, p < 0.001), and the lowest rate of anterograde and retrograde collaterals (19%, p < 0.001; 66%, p = 0.002). The anterograde collaterals were associated with higher relative cerebral blood volume (0.91 vs. 0.77; p = 0.024) and a higher rate of deep cerebral microbleeds (48 vs. 21%; p = 0.028), whereas retrograde collaterals were associated with higher systolic and diastolic blood pressure ( p = 0.031 and 0.020), smaller initial infarction volume (0.81 vs. 1.34 ml, p = 0.031), and a higher rate of lobar cerebral microbleeds (30 vs. 0%; p = 0.013). Both anterograde and retrograde collaterals may play a critical role in maintaining cerebral perfusion and can have an impact on patient clinical outcomes. Further studies are warranted to verify these findings and to investigate effective treatments.

The association of cerebrospinal fluid pressure with optic nerve head and macular vessel density - Xiangxiang Liu; Mohamed M. Khodeiry; Danting Lin; Yunxiao Sun; Qing Zhang; Jiawei Wang; Richard K. Lee; Ningli Wang (Science China Life Sciences, 2022)

Activation of Neuropeptide Y2 Receptor Can Inhibit Global Cerebral Ischemia-Induced Brain Injury - Reggie Hui-Chao Lee; Celeste Yin-Chieh Wu; Cristiane T. Citadin; Alexandre Couto e Silva; Harlee E. Possoit; Garrett A. Clemons; Christina H. Acosta; Victoria A. de la Llama; Jake T. Neumann; Hung Wen Lin (NeuroMolecular Medicine, 2022)

Use of piggyBac Transposon System Constructed Murine Breast Cancer Model for Reporter Gene Imaging and Characterization of Metastatic Tumor Cells - Ying-Ling Chen; Yung-Cheng Wang; Kuei-Yuan Hou; Min-Ying Lin; Yu-Chuan Lin; Hui-Yen Chuang; Yi-Jang Lee (Journal of Medical and Biological Engineering, 2022)

Long-term exercise pre-training attenuates Alzheimer’s disease–related pathology in a transgenic rat model of Alzheimer’s disease - Luodan Yang; Chongyun Wu; Yong Li; Yan Dong; Celeste Yin-Chieh Wu; Reggie Hui-Chao Lee; Darrell W. Brann; Hung Wen Lin; Quanguang Zhang (GeroScience, 2022)

Genotype-Environment-Management Interactions in Biomass Yield and Feedstock Composition of Photoperiod-Sensitive Energy Sorghum - August Schetter; Cheng-Hsien Lin; Colleen Zumpf; Chunhwa Jang; Leo Hoffmann; William Rooney; D. K. Lee (BioEnergy Research, 2022)

Cholesterol Accumulation in Livers of Indian Medaka, Oryzias dancena, Acclimated to Fresh Water and Seawater - Naveen Ranasinghe; Chia-Hao Lin; Tsung-Han Lee (Frontiers in Marine Science, 2022)
Sterol regulatory-element binding proteins (SREBPs), sirtuin (SIRT1), and liver X receptor α (LXRα) play important roles in regulating cholesterol metabolism in mammals. However, little is known about the relationship between cholesterol metabolism and SIRT1, LXRα, and SREBP-1 in fish. In addition, knowledge of the effects of salinity on hepatic cholesterol metabolism in euryhaline teleosts is fragmented. This study revealed that hepatic cholesterol content was significantly different between fresh water (FW)- and seawater (SW)-acclimated Indian medaka. Gene expression analysis indicated srebp-1 , lxrα , and sirt1 transcripts were not affected by changes in ambient salinity. However, SREBP-1, but not LXRα and SIRT1 protein expression, was significantly induced in the liver of FW-acclimated medaka. When SREBP-1 Vivo-MO inhibited SREBP-1 translation, hepatic cholesterol content was predominantly downregulated in FW- and SW-acclimated medaka. This is the first study to show that SREBP-1 is involved in cholesterol biosynthesis in fish. Furthermore, SREBP-1 knockdown had different effects on the expression of hmgcr and fdps , which encode the key enzymes involved in cholesterol biosynthesis. This study further enhances our knowledge of cholesterol metabolism in the livers of euryhaline teleosts during salinity acclimation.

A Time-Domain Analytic Solution of Flow-Induced Undular Bores - Cheng-Tsung Chen; Jaw-Fang Lee; Hubert Chanson; Kuei-Ting Lin; Chun-Jih Lin (Journal of Marine Science and Engineering, 2022)
In this study, the problem of surface waves induced by water flow in a flow channel was investigated. The mathematical model based on the potential wave theory was established, and a new analytic solution to the corresponding initial and boundary value problem was proposed. To confirm our analytic solution, the mathematical model was applied to simulate experiments conducted in a flow channel in the laboratory. Using our analytic solution, water surface elevations and flow velocities at certain locations in the channel were compared with experimental results. Comparisons between our analytic solution and experimental results confirmed our theory that amplitudes and propagating phases are in very close agreement. Our analytic solution can be used to calculate variations in pressure and velocity along the water depth, which are expensive to calibrate and obtain in experiments. Although our analytic solution was established based on linear theory, it is very practical for applications studying the basic properties of surface elevation, velocity, and pressure of the flow field induced by water current both in space and time.

Natural Feed Supplements Improve Growth, Non-Specific Immune Responses and Resistance against Vibrio alginolyticus in Lates calcarifer - Zhen-Hao Liao; Huai-Ting Huang; Yu-Ru Lin; Bo-Ying Chen; Yi-Fan Lee; Yuan-Heng Lin; Chieh-Yuan Chuang; Fan-Hua Nan (Journal of Marine Science and Engineering, 2022)
This study aimed to investigate the effects of dietary natural feed supplement on the growth performance, non-specific responses, and disease resistance in Lates calcarifer. Three commercial products (A, B, and C) containing a basal probiotic mixture were tested. Product A contained a basal mixture of Paenibacillus sp., Bacillus subtilis, Bacillus amyloliquefaciens, and Lactobacillus rhamnosus (107 cfu/g for each probiotic); product B contained additional Lactobacillus plantarum (1010 cfu/g); and product C contained additional soybean peptides (500 g/kg) and garlic powder (1 g/kg). Each product was supplemented into subject diets at dosages of 1 or 2 g/kg (designated as the A1, A2, B1, B2, C1, and C2 groups, respectively). Following an eight-week trial, growth parameters (specific growth rate and feed conversion ratio), non-specific immune responses (O2− production, phagocytic rate, and phagocytic index), and the results of a challenge test against Vibrio alginolyticus were evaluated. The results show that all probiotic supplement groups exhibited an improvement in growth performance compared to the control group (non-probiotic diet). In terms of non-specific immunity parameters, a significant improvement in O2− production was found in the C2 group, whereas significant improvements in phagocytic activity were found in all the B and C groups. The C2 group displayed optimal O2− production, phagocytic rate, and phagocytic index results. For the challenge test, the C groups showed higher Vibrio resistance than the other experimental groups and the control group. These results suggest that product C, given at dosages of 2 g/kg, may serve as a growth-promoting and immunostimulatory additive for the cultivation of Asian seabass.

Cracking and Photo-Oxidation of Polyoxymethylene Degraded in Terrestrial and Simulated Marine Environments - Chih-Cheng Tang; Ying-Ting Chen; Yi-Ming Zhang; Huey-Ing Chen; Peter Brimblecombe; Chon-Lin Lee (Frontiers in Marine Science, 2022)
Marine plastic debris is an environmental problem, and its degradation into microplastics (1-5000 μm) introduces them into the food chain. In this study, small polyoxymethylene (global production ~3000 Tg per year) pellets were exposed in terrestrial and simulated marine environments to heat and light, resulting in cracking during decay with increasing IR absorption (OH-bonds). Furthermore, sunlight over three years reduced pellet mass and diameter (~10% and ~40%), initially yielding 100-300 μm fragments. Changes under UV irradiation were smaller as it could not penetrate into particle interiors. Characteristic spacing of surface striations (100-300 µm) initiated radial cracks to pellet interiors, and breakdown ultimately meant 95% of particles were <300 µm, which are potentially incorporated in marine turbidites.

Hypothermal Effects on Energy Supply for Ionocytes in Gills of Freshwater- and Seawater-Acclimated Milkfish, Chanos chanos - Chia-Hao Chang; Chia-Jui Liu; Wei-Jie Lu; Li-Yang Wu; Kuang-Jie Lai; Yu-Ting Lin; Tsung-Han Lee (Frontiers in Marine Science, 2022)
The milkfish, Chanos chanos , is an important aquaculture species that can be cultured in freshwater (FW) and seawater (SW) ponds because of its high euryhalinity. In winter, cold snap leading to high mortality of this tropical species is a critical issue for the aquaculture industry in Taiwan. Under hypothermal stress, however, changes in energy supply for osmoregulation of this euryhaline species is intriguing. In this study, we used an antibody against glycogen phosphorylase (GP) to identify glycogen-rich (GR) cells distributed adjacent to the mitochondria-rich (MR) ionocytes in milkfish gills. Glucose transporter 1 (GLUT1), which plays a major role in energy supply, was also identified and localized in GR cells. Moreover, the expression of indicators of aerobic metabolism and energy production, citrate synthase (CS) and cytochrome c oxidase (COX), were analyzed in gills of FW- and SW-acclimated milkfish to reveal different strategies of energy utilization under hypothermal stress. When exposed to a low-temperature environment, SW individuals used branchial glycogen and lactate to match the energy demands of aerobic metabolism in ionocytes, and elevated aerobic capacity to support and maintain normal functions in gills. However, branchial glycogen mainly localized in the GR cells of FW milkfish was not utilized under hypothermal stress. Meanwhile, a similar level of branchial COX activity and COXIV protein abundance at low temperatures between FW and SW milkfish indicated similar energy requirements in gills. This suggested that another source, but not branchial glycogen, maintained the energy demand in FW milkfish. The present study illustrated differential energy supply strategies in gills between SW- and FW-acclimated milkfish for osmoregulation under low temperatures.

Dilated Generative Adversarial Networks for Underwater Image Restoration - Jao-Chuan Lin; Chih-Bin Hsu; Jen-Chun Lee; Chung-Hsien Chen; Te-Ming Tu (Journal of Marine Science and Engineering, 2022)
Underwater images often come with blurriness, lack of contrast, and low saturation due to the physics of light propagation, absorption, and scattering in seawater. To improve the visual quality of underwater images, many have proposed image processing methods that vary based on different approaches. We use a generative adversarial network (GAN)-based solution and generate high-quality underwater images equivalent to given raw underwater images by training our network to specify the differences between high-quality and raw underwater images. In our proposed method, which is called dilated GAN (DGAN), we add an additional loss function using structural similarity. Moreover, this method can not only determine the realness of the entire image but also functions with classification ability on each constituent pixel in the discriminator. Finally, using two different datasets, we compare the proposed model with other enhancement methods. We conduct several comparisons and demonstrate via full-reference and nonreference metrics that the proposed approach is able to simultaneously improve clarity and correct color and restores the visual quality of the images acquired in typical underwater scenarios.

Effect of High-Pressure Treatment on Blue Marlin ( Makaira nigricans ) Quality During Storage - Yi-Chen Lee; Hsien-Feng Kung; Shao-Lan Chen; Chung-Saint Lin; Chun-Yung Huang; Osamu Arakawa; Chih-Hua Tseng; Yung-Hsiang Tsai (Journal of Aquatic Food Product Technology, 2022)

Potential Plasticity of Artificial Feed Preference in Juvenile Pharaoh Cuttlefish (Sepia pharaonis) Through Progressive Training Programs - Chia-Huan Ma; Chih-Hung Lin; Yung-Cheng Chang; Hung-Tai Lee; Chyng-Hwa Liou; Te-Hua Hsu (Frontiers in Marine Science, 2022)
The cuttlefish is a commercially important marine species across the world; however, due to the lack of appropriate artificial feed, there is limited future aquaculture development of the cuttlefish. We proposed a novel process comprising (1) feed preference tests and (2) progressive training programs. Through this process, artificial diets can become more suitable for pharaoh cuttlefish ( Sepia pharaonis ). Feed preference tests (based on vision, touch, and smell) revealed that pharaoh cuttlefish preferred rod-shaped feed to flat rod-shaped or ball-shaped feed, moist feed over dry feed (DF), and DF with agar coating to DF without agar coating. Without olfactory training, some cuttlefish refused to eat artificial feed and eventually died. Through progressive training programs (3- and 6-week programs), a survival rate of >80% was achieved. Although the artificial diets examined in this study resulted in a lower conversion ratio for S. pharaonis than for fresh shrimp, available artificial feed can potentially be adopted for cuttlefish aquaculture through the use of our progressive training program.

Towards a rapid assessment of highway slope disasters by using multidisciplinary techniques - Meng-Chia Weng; Cheng-Han Lin; Wen-Jie Shiu; Wei-An Chao; Chia-Chi Chiu; Ching-Fang Lee; Wei-Kai Huang; Che-Ming Yang (Landslides, 2022)
Mega-earthquakes and extreme climate events accompanied by intrinsic fragile geology lead to numerous landslides along mountain highways in Taiwan, causing enormous life and economic losses. In this study, a system for rapid slope disaster information integration and assessment is proposed with the aim of providing information on landslide occurrence, failure mechanisms, and subsequent landslide-affected areas to the highway authority rapidly. The functionality of the proposed system is deployed into three units: (1) geohazard rapid report (GeoPORT I), (2) multidisciplinary geological survey report (GeoPORT II), and (3) site-specific landslide simulation report (GeoPORT III). After landslide occurrence, the seismology-based monitoring network rapidly provides the initial slope disaster information, including preliminary location, event magnitude, earthquake activity, and source dynamics, within an hour. Within 3 days of the landslide, a multidisciplinary geological survey is conducted to collect high-precision topographical, geological, and remote-sensing data to determine the possible failure mechanism. After integrating the aforementioned information, a full-scale three-dimensional landslide simulation based on the discrete element method is performed within 10 days to reveal the failure process and to identify the areas potentially affected by subsequent disasters through scenario modeling. Overall, the proposed system can promptly provide comprehensive and objective information to relevant authorities after the event occurrence for hazard assessment. The proposed system was validated using a landslide event in the Central Cross-Island Highway of Taiwan.

The Emerging Biotherapeutic Agent: Akkermansia - Vipin Chandra Kalia; Chunjie Gong; Ramasamy Shanmugam; Hui Lin; Liaoyuan Zhang; Jung-Kul Lee (Indian Journal of Microbiology, 2022)

Application of Soil and Water Assessment Tool (SWAT) to evaluate the fates of nitrogenous fertilizer in subtropical mountainous watershed tea farms - Guan-Zhou Lin; Shao-Yiu Hsu; Chia-Chun Ho; Chi-Feng Chen; Jr-Chuan Huang; Tsung-Yu Lee (Environmental Monitoring and Assessment, 2022)

Spatiotemporal distribution and the passive dispersal of fungal spores through HVAC systems - Wan-Rou Lin; Yung-Hung Ho; Wai Kwan Lee; Hsuan-Min Cheng; Pi-Han Wang (Aerobiologia, 2022)

Microbiome Associated With Gambierdiscus balechii Cultures Under Different Toxicity Conditions - Zhen Wu; Wai Hin Lee; Zijian Liu; Senjie Lin; Paul K. S. Lam (Frontiers in Marine Science, 2022)
Dinoflagellates, including harmful algal bloom species, are known to co-exist with and rely upon bacteria but how the microbiome changes with the physiologies of the cognate dinoflagellates is poorly understood. Here, we used 16S rRNA gene meta-barcoding to characterize the bacterial community in the cultures of Gambierdiscus balechii , a ciguatoxin-producing benthic dinoflagellate, under different nitrogen (N)-nutrient conditions and at different ciguatoxin-producing growth. The high-throughput sequencing of a total of 12 libraries generated 926,438 reads which were classified into 16 phyla. We observed a shift of the G. balechii -associated microbiome from N-replete to low-N conditions and from the early (low toxin) to the late exponential (high toxin) growth stage. Common across these conditions were species from families Rhodobacteraceae and Flavobacteriaceae. Species abundant in the low-N condition mainly included Planctomyces , Ekhidna , and Lactobacillus. Dominant or highly abundant microbial taxa in the high toxin-producing stage (N-replete, late exponential stage) were Oceanococcus and Marinoscillum . Under this condition, one Rhizobiales bacterium, Oricola , also increased in relative abundance. Our study documents the high diversity and dynamics of the G. balechii -associated microbiome, and identifies condition-specific sub-communities: the core (constitutive) microbiome that stably co-exists with G. balechii , the bacterial lineages that are responsive to N-nutrient variations, and species whose abundances are correlated with toxin content of the dinoflagellate. These findings demonstrate that particular bacterial groups are responsive to N-nutrient or toxicity changes of G. balechii and thus will be useful for further investigations on the associated microbiome’s interactions with benthic dinoflagellates and functions in the course of benthic harmful algae blooms.

Paleoproterozoic to Cenozoic zircon U–Pb ages with Hf signatures from metamorphic rocks and granodiorite of Tokunoshima: constraints on the geotectonic subdivision of the Ryukyu island arc, Southwest Japan - Hiroshi Yamamoto; Kazuaki Okamoto; Sun-Lin Chung; Hao-Yang Lee; Yuji Mita; Shuro Ueda; Masaru Terabayashi (International Geology Review, 2022)

Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation - Yu-Che Cheng; Chi-Jung Huang; Wei-Chi Ku; Shu-Lin Guo; Lu-Tai Tien; Yih-Jing Lee; Chih-Cheng Chien (Stem Cell Reviews and Reports, 2022)
Little is known about genes that induce stem cells differentiation into astrocytes. We previously described that heat shock protein 27 (HSP27) downregulation is directly related to neural differentiation under chemical induction in placenta-derived multipotent stem cells (PDMCs). Using this neural differentiation cell model, we cross-compared transcriptomic and proteomic data and selected 26 candidate genes with the same expression trends in both omics analyses. Those genes were further compared with a transcriptomic database derived from Alzheimer’s disease (AD). Eighteen out of 26 candidates showed opposite expression trends between our data and the AD database. The mRNA and protein expression levels of those candidates showed downregulation of HSP27, S100 calcium-binding protein A16 (S100A16) and two other genes in our neural differentiation cell model. Silencing these four genes with various combinations showed that co-silencing HSP27 and S100A16 has stronger effects than other combinations for astrocyte differentiation. The induced astrocyte showed typical astrocytic star-shape and developed with ramified, stringy and filamentous processes as well as differentiated endfoot structures. Also, some of them connected with each other and formed continuous network. Immunofluorescence quantification of various neural markers indicated that HSP27 and S100A16 downregulation mainly drive PDMCs differentiation into astrocytes. Immunofluorescence and confocal microscopic images showed the classical star-like shape morphology and co-expression of crucial astrocyte markers in induced astrocytes, while electrophysiology and Ca 2+ influx examination further confirmed their functional characteristics. In conclusion, co-silencing of S100A16 and HSP27 without chemical induction leads to PDMCs differentiation into functional astrocytes. Graphical abstract

Structure related α-glucosidase inhibitory activity and molecular docking analyses of phenolic compounds from Paeonia suffruticosa - Po-Chun Chen; Bongani Sicelo Dlamini; Chiy-Rong Chen; Yueh-Hsiung Kuo; Wen-Ling Shih; Yun-Sheng Lin; Chien-Hsing Lee; Chi-I Chang (Medicinal Chemistry Research, 2022)

Non-immune functions of inflammatory cytokines targeted by anti-psoriatic biologics: a review - Tung-Lin Lee; Tsen-Fang Tsai (Inflammation Research, 2022)

Dietary nutrients shape gut microbes and intestinal mucosa via epigenetic modifications - Jianmin Wu; Ying Zhao; Xian Wang; Lingchang Kong; Lee J. Johnston; Lin Lu; Xi Ma (Critical Reviews in Food Science and Nutrition, 2022)

Historical Connectivity and Demography of the Ferocious Reef Crab, Eriphia ferox (Crustacea; Eriphiidae), Demonstrate That Taoyuan Algal Reef Is an Essential Population Source Along the East Taiwan Strait - Mu-Han Chen; Ya-Yi Huang; Bi-Ying Huang; Hernyi Justin Hsieh; Jen Nie Lee; Mei Lin Neo; Hironobu Fukami; Chaolun Allen Chen (Frontiers in Marine Science, 2022)
The east Taiwan Strait is largely fringed by sandy and muddy habitats. However, a massive algal reef made of crustose coralline algae has been found along the coast off Taoyuan city in northwestern Taiwan. The porous structure of Taoyuan Algal Reef harbors high abundance and diversity in marine organisms, including the ferocious reef crab, Eriphia ferox . Such a pivotal geographic location and unique ecological features make Taoyuan Algal Reef a potential stepping stone connecting biotic reefs in the east Taiwan Strait, South China Sea to the south, and even the high latitude of Japan to the north. In this study, we examined the population connectivity and historical demography of E. ferox by analyzing mitochondrial cytochrome oxidase I (COI) fragments of 317 individuals sampled from 21 localities in the northwestern Pacific. Our analyses of haplotype network and pairwise F ST comparisons revealed a lack of phylogeographical structure among E. ferox populations, implying the existence of a migration corridor connecting the South and East China Seas through the east Taiwan Strait. Multiple lines of evidence, including significant values in neutrality tests, unimodally shaped mismatch distributions, and Bayesian skyline plots elucidated the rapid population growth of E. ferox following the sea-level rise after Last Glacial Maximum (ca. 2–10 Ka). Such demographic expansion in E. ferox coincided with the time when Taoyuan Algal Reef started to build up around 7,500 years ago. Coalescent migration analyses further indicated that the large and continuous E. ferox population exclusively found in Datan Algal Reef, the heart of Taoyuan Algal Reef, was a source population exporting migrants both northward and southward to the adjacent populations. The bidirectional gene flow should be attributed to larval dispersal by ocean currents and secondary contact due to historical population expansion. Instead of serving as a stepping stone, our results support that Taoyuan Algal Reef is an essential population source for biotic reef-associated species along the east Taiwan Strait, and highlight the importance of conserving such a unique ecosystem currently threatened by anthropogenic development.

Improved method for measuring the δ15N compound-specific amino acids: Application on mesopelagic fishes in the South China Sea - Fuqiang Wang; Ying Wu; Lin Zhang; Jie Jin; Zuozhi Chen; Jun Zhang; Wing-man Lee (Acta Oceanologica Sinica, 2022)

Intramyocardial injection of human adipose-derived stem cells ameliorates cognitive deficit by regulating oxidative stress–mediated hippocampal damage after myocardial infarction - Tsung-Ming LEE; Cheng-Che LEE; Horng-Jyh HARN; Tzyy-Wen Chiou; Ming-Hsi CHUANG; Chun-Hung CHEN; Chi-Hsuan CHUANG; Po-Cheng LIN; Shinn-Zong LIN (Journal of Molecular Medicine, 2021)
Cognitive impairment is a serious side effect of post-myocardial infarction (MI) course. We have recently demonstrated that human adipose-derived stem cells (hADSCs) ameliorated myocardial injury after MI by attenuating reactive oxygen species (ROS) levels. Here, we studied whether the beneficial effects of intramyocardial hADSC transplantation can extend to the brain and how they may attenuate cognitive dysfunction via modulating ROS after MI. After coronary ligation, male Wistar rats were randomized via an intramyocardial route to receive either vehicle, hADSC transplantation (1 × 10 6 cells), or the combination of hADSCs and 3-Morpholinosydnonimine (SIN-1, a peroxynitrite donor). Whether hADSCs migrated into the hippocampus was assessed by using human-specific primers in qPCR reactions. Passive avoidance test was used to assess cognitive performance. Postinfarction was associated with increased oxidative stress in the myocardium, circulation, and hippocampus. This was coupled with decreased numbers of dendritic spines as well as a significant downregulation of synaptic plasticity consisting of synaptophysin and PSD95. Step-through latency during passive avoidance test was impaired in vehicle-treated rats after MI. Intramyocardial hADSC injection exerted therapeutic benefits in improving cardiac function and cognitive impairment. None of hADSCs was detected in rat’s hippocampus at the 3rd day after intramyocardial injection. The beneficial effects of hADSCs on MI-induced histological and cognitive changes were abolished after adding SIN-1. MI-induced ROS attacked the hippocampus to induce neurodegeneration, resulting in cognitive deficit. The remotely intramyocardial administration of hADSCs has the capacity of improved synaptic neuroplasticity in the hippocampus mediated by ROS, not the cell engraftment, after MI. Key messages Human adipose-derived stem cells (hADSCs) ameliorated injury after myocardial infarction by attenuating reactive oxygen species (ROS) levels. Intramyocardial administration of hADSCs remotely exerted therapeutic benefits in improving cognitive impairment after myocardial infarction. The improved synaptic neuroplasticity in the hippocampus was mediated by hADSC-inhibiting ROS, not by the stem cell engraftment.

Realization of Natural Human Motion on a 3D Biped Robot For Studying the Exoskeleton Effective - Chi-Ying Lee; Shih Chieh Lan; Jung-Ji Lin; Yu-Ting Lin; Po-Shen Chiang; Wei-Li Hsu; Kuo-Kuang Jen; Andy Y. S. Huang; Jia-Yush Yen (Journal of Medical and Biological Engineering, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Effect of heat stress on oxidative damage and antioxidant defense system in white clover (Trifolium repens L.) - Hsiang-Lin Liu; Zhu-Xuan Lee; Tzu-Wei Chuang; Hui-Chen Wu (Planta, 2021)

A Rhizobium bacterium and its population dynamics under different culture conditions of its associated toxic dinoflagellate Gambierdiscus balechii - Zhen Wu; Xiaohong Yang; Senjie Lin; Wai Hin Lee; Paul K. S. Lam (Marine Life Science & Technology, 2021)

Streptococcus vaginalis sp. nov., a novel bacterial species isolated from vaginal swabs of a pregnant woman with diabetes - An-Shine Chao; Chiao-Yun Lin; Angel Chao; Yun-Shien Lee; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Yi-Sheng Chen (Archives of Microbiology, 2021)

Dynamic Regulation of Ions and Amino Acids in Adult Asian Hard Clams Meretrix lusoria Upon Hyperosmotic Salinity - Chia-Hao Lin; Po-Ling Yeh; Yu-Chun Wang; Tsung-Han Lee (Frontiers in Marine Science, 2021)
The dynamic regulation of ions and amino acids in the gills and mantle of the Asian hard clam, Meretrix lusoria , following the exposure to a hyperosmotic environment was hitherto unclear. The present study revealed that the osmolality as well as the Na + and Cl – concentrations in the hemolymph were significantly increased 3 h after transferring the clams from an environment with the salinity of their natural habitat (brackish water; BW; 20‰) to one with hyperosmotic salinity (seawater; 35‰). In addition, we found that the specific activities of Na + /K + -ATPase, a key enzyme that plays a significant role in cell osmoregulation, in the gills and mantle of clams were significantly increased at 72 and 12 h post-transfer, respectively, during acclimation to hyperosmotic salinity. Similarly, the contents of free amino acids (FAAs) such as taurine, alanine, and glycine were significantly elevated during hyperosmotic salinity acclimation. Previous research indicates that taurine is the most abundant FAA in the gills and mantles of Asian hard clams and that the taurine transporter (TAUT) plays an important role in taurine accumulation. The present study showed that TAUT mRNA and protein expression were significantly and transiently increased in the mantle of Asian hard clams following exposure to seawater; although the expression of TAUT mRNA in the gills of Asian hard clams was also transiently stimulated by exposure to hyperosmotic salinity, the relative TAUT protein abundance decreased only at later stages. Accordingly, the findings of this study improve our understanding of the dynamic processes of ion and amino acid regulation in the peripheral tissues of bivalves under hyperosmotic stress.

Rac1 and Akt Exhibit Distinct Roles in Mediating Aβ-Induced Memory Damage and Learning Impairment - Kuan-Chung Cheng; Ying-Hao Chen; Chia-Lin Wu; Wang-Pao Lee; Chun Hei Antonio Cheung; Hsueh-Cheng Chiang (Molecular Neurobiology, 2021)

Comparing the clinical outcomes across different sodium/glucose cotransporter 2 (SGLT2) inhibitors in heart failure patients: a systematic review and network meta-analysis of randomized controlled trials - Yao Hao Teo; Celine Shuen Yin Yoong; Nicholas L. Syn; Yao Neng Teo; Jia Yang Alex Cheong; Yoke-Ching Lim; Chi-Hang Lee; Tiong-Cheng Yeo; Ping Chai; Raymond C. C. Wong; Weiqin Lin; Ching-Hui Sia (European Journal of Clinical Pharmacology, 2021)

Neurological diseases and COVID-19: prospective analyses using the UK Biobank - Nicola Veronese; Lee Smith; Mario Barbagallo; Gianluigi Giannelli; Maria Gabriella Caruso; Anna Maria Cisternino; Maria Notarnicola; Chao Cao; Thomas Waldhoer; Lin Yang (Acta Neurologica Belgica, 2021)
COVID-19 (Coronavirus disease-19) may present with neurological signs, but whether people already affected by neurological conditions are at a higher risk of contracting COVID-19 is still not known. We, therefore, aimed to investigate the association of previously diagnosed neurological conditions with COVID-19. 502,536 community-dwelling UK Biobank participants (54.4% male, mean age 56.6 ± 10.3 years) were included. Among these, 57,463 participants had a diagnosis of neurological conditions (11.43%) and a total of 1326 COVID-19-positive cases were identified (0.26%). Neurological conditions were identified through medical history and linkage to data on hospital admissions (ICD-10 code G00–G99). COVID-19 presence was diagnosed using the data provided by Public Health England. The association of previous diagnosis of neurological conditions with COVID-19 was evaluated through logistic regressions, adjusted for potential confounders, reported as odds ratios (ORs) with their 95% confidence intervals (CIs). Nerve, nerve root and plexus disorders (G50–G59) were the most common conditions identified. The presence of COVID-19 was almost doubled in neurological conditions compared to the general population (0.45 vs. 0.24%, p

Vagus nerve stimulation in pediatric patients with failed epilepsy surgery - Jeng-Dau Tsai; Pi-Chuan Fan; Wang-Tso Lee; Pi-Lien Hung; Kun-Long Hung; Huei-Shyong Wang; Kuang-Lin Lin (Acta Neurologica Belgica, 2021)

Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice - Thomas H Lee; Ahadullah; Brian R Christie; Kangguang Lin; Parco Ming-fai Siu; Li Zhang; Ti-fei Yuan; Pragya Komal; Aimin Xu; Kwok-fai So; Suk-yu Yau (Molecular Neurobiology, 2021)
Administration of exercise mimetic drugs could be a novel therapeutic approach to combat comorbid neurodegeneration and metabolic syndromes. Adiponectin is an adipocyte-secreted hormone. In addition to its antidiabetic effect, adiponectin mediates the antidepressant effect of physical exercise associated with adult hippocampal neurogenesis. The antidiabetic effect of the adiponectin receptor agonist AdipoRon has been demonstrated, but its potential pro-cognitive and neurotrophic effects in the hippocampus under diabetic condition are still unclear. This study reported that chronic AdipoRon treatment for 2 weeks improved hippocampal-dependent spatial recognition memory in streptozotocin-induced diabetic mice. Besides, AdipoRon treatment increased progenitor cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (DG) of diabetic mice. Furthermore, AdipoRon treatment significantly increased dendritic complexity, spine density, and N -methyl-D-aspartate receptor-dependent long-term potentiation (LTP) in the dentate region, and increased BDNF levels in the DG of diabetic mice. AdipoRon treatment activated AMPK/PGC-1α signalling in the DG, whereas increases in cell proliferation and LTP were not observed when PGC-1α signalling was pharmacologically inhibited. In sum, chronic AdipoRon treatment partially mimics the benefits of physical exercise for learning and memory and hippocampal neuroplasticity in the diabetic brain. The results suggested that AdipoRon could be a potential physical exercise mimetic to improve hippocampal plasticity and hence rescue learning and memory impairment typically associated with diabetes.

A study on the relationships of place attachment and individual attributes of residents in different vulnerable districts in Taipei, Taiwan - Yung-Jaan Lee; Shih-Ying Lin (Environmental Science and Pollution Research, 2021)

Dating deformation using sheared leucogranite: temporal constraints by 40Ar/39Ar thermochronology for the Mae Ping shear zone, NW Thailand - Yu-Ling Lin; Tung-Yi Lee; Ching-Hua Lo; Sarah C. Sherlock; Yoshiyuki Iizuka; Tadashi Usuki; Long Xiang Quek; Punya Charusiri (Contributions to Mineralogy and Petrology, 2021)

The Macrobrachium rosenbergii nodavirus: a detailed review of structure, infectivity, host immunity, diagnosis and prevention - Ken Fong Chen; Wen Siang Tan; Lin Kooi Ong; Syafiq Asnawi Zainal Abidin; Iekhsan Othman; Beng Ti Tey; Ronald Fook Seng Lee (Reviews in Aquaculture, 2021)
The Macrobrachium rosenbergii nodavirus causes white tail disease, which primarily infects giant freshwater prawns, Macrobrachium rosenbergii . The infection leads to almost 100% mortality in post‐larvae, causing significant economic losses in aquaculture farms. To develop effective measures against outbreaks, a good understanding of the virus is essential. In this review, we discuss key aspects of the Macrobrachium rosenbergii nodavirus including its structure, mechanisms of transmission and infection and common strategies for detection and prevention of outbreaks. Structurally, cryogenic electron microscopy revealed that the nodavirus has a T = 3 icosahedral structure with dimeric blade‐like spikes on its surface. Homology modelling comparing wild‐type and enzymatically cleaved Macrobrachium rosenbergii nodavirus‐like particles revealed the significance of these spikes or protruding domains for binding. In vitro and in vivo studies have identified key aspects of Macrobrachium rosenbergii nodavirus infectivity, including (i) the viral binding targets such as transglutaminase and caveolin‐1, (ii) utilisation of B2‐like proteins in promoting infectivity and intracellular migration, (iii) replication mechanisms and (iv) co‐infection with the extra small virus. Though susceptible at a post‐larvae stage, adult Macrobrachium rosenbergii is immune to Macrobrachium rosenbergii nodavirus infection. During outbreaks, polymerase chain reaction and in situ hybridisation‐based detection techniques are commonly used to identify infected populations. Currently, the most useful strategies for an outbreak are physical biosecurity measures and prophylaxis such as vaccination and immunostimulants. Finally, critical gaps in research include development of immortalised shrimp cell models, elucidation of time‐resolved protein changes post‐infection and development of therapies to treat infections to mitigate economic losses during outbreaks.

Biomechanical Evaluation of a Fin-type Implant Compared to Traditional Buttress Plate for the Stabilization of the Posteromedial Fragment in Tibial Plateau Split Fractures - Jian-Chih Chen; Kang-Ping Lin; Tien-Ching Lee; Yin-Chih Fu; Kun-Jhih Lin (Journal of Medical and Biological Engineering, 2021)

New ent -kauran diterpene and antioxidant components from the seed of Ipomoea nil - Chia-Lin Lee; Pei-Ting Lo; Yun-Lian Jhan; Chao-Jung Chen; Yuan-Shiun Chang (Natural Product Research, 2021)

Nucleophosmin/B23 promotes endometrial cancer cell escape from macrophage phagocytosis by increasing CD24 expression - Chiao-Yun Lin; Chia-Lung Tsai; Angel Chao; Li-Yu Lee; Wei-Chun Chen; Yun-Hsin Tang; An-Shine Chao; Chyong-Huey Lai (Journal of Molecular Medicine, 2021)

Risk of two common glandular cell-type cancers (breast and colorectal cancers) in Chinese occupational chefs: a nationwide ecological study in Taiwan - Pei-Chen Lin; Chiung‑Yu Peng; Chih‑Hong Pan; Jui-Ying Lee; Tusty-Jiuan Hsieh; Yun-Shiuan Chuang; Robert J. Turesky; Chia-Fang Wu; Ming-Tsang Wu (International Archives of Occupational and Environmental Health, 2021)

Recycle of synthetic calcium fluoride and waste sulfuric acid to produce electronic grade hydrofluoric acid - Min-Fa Lin; Jhong-Lin Wu; Ken-Lin Chang; Wen-Jhy Lee; Chih-Ping Chang; Yung-Chang Lin; Po-Han Chen (Environmental Science and Pollution Research, 2021)

Economic growth in selected G20 countries: How do different pollution emissions matter? - Thian-Hee Yiew; Chin-Yu Lee; Lin-Sea Lau (Environment, Development and Sustainability, 2021)

Extreme climate changes over three major river basins in China as seen in CMIP5 and CMIP6 - Xian Zhu; Shao-Yi Lee; Xiaohang Wen; Zhenming Ji; Lei Lin; Zhigang Wei; Zhiyuan Zheng; Danya Xu; Wenjie Dong (Climate Dynamics, 2021)

Spatiotemporal analysis of temperature data trends in Peninsular Malaysia - Hun Vui Woo; Jing Lin Ng; Yuk Feng Huang; Celine Chong; Jin Chai Lee (Arabian Journal of Geosciences, 2021)

Trichome Lengths of the Heterocystous N2-Fixing Cyanobacteria in the Tropical Marginal Seas of the Western North Pacific - Sing-how Tuo; Margaret R. Mulholland; Yukiko Taniuchi; Houng-Yung Chen; Wann-Neng Jane; Yen-Huei Lin; Yuh-ling Lee Chen (Frontiers in Marine Science, 2021)
Calothrix rhizosoleniae and Richelia intracellularis are heterocystous cyanobacteria found in the tropical oceans. C. rhizosoleniae commonly live epiphytically on diatom genera Chaetoceros ( C-C ) and Bacteriastrum ( B-C ) while R. intracellularis live endosymbiotically within Rhizosolenia ( R-R ), Guinardia ( G-R ), and Hemiaulus ( H-R ); although, they occasionally live freely (FL- C and FL- R ). Both species have much shorter trichomes than the other marine filamentous cyanobacteria such as Trichodesmium spp. and Anabaena gerdii . We investigated the trichome lengths of C. rhizosoleniae and R. intracellularis in the South China Sea (SCS) and the Philippine Sea (PS) between 2006 and 2014. On average, H-R had the shortest trichome lengths (3.5 cells/trichome), followed by B-C and C-C (4.9–5.2 cells/trichome) and FL- C (5.9 cells/trichome), and R-R , G-R , and FL- R had the longest trichome lengths (7.4–8.3 cells/trichome). Field results showed the trichome lengths of C-C and B-C did not vary seasonally or regionally. However, FL- C and H-R from the SCS and during the cool season had longer trichomes, where/when the ambient nutrient concentrations were higher. R-R , G-R , and FL- R also showed regional and seasonal variations in trichome length. Ultrastructural analysis found no gas vesicles within the C. rhizosoleniae cells to assist in buoyancy regulation. Results suggest that the trichome lengths of C. rhizosoleniae and R. intracellularis might be regulated by their diatom hosts’ symbiotic styles and by ambient nutrients. Short trichome length might help C. rhizosoleniae and R. intracellularis to stay in the euphotic zone regardless as to whether they are free-living or symbiotic.

Investigating the use of environmental tableware based on the theory of planned behavior - Jui-Che Tu; Yu-Yin Chen; Yi-Lin Lee; Xiao-Lin Wang (Environment, Development and Sustainability, 2021)

Vibrio nitrifigilis sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll - Wei-Sheng Huang; Li-Ting Wang; Jwo-Sheng Chen; Yen-Ting Chen; Sean Ting-Shyang Wei; Yin-Ru Chiang; Pei-Ling Wang; Tzong-Huei Lee; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2021)

Detection of Vestibular Schwannoma on Triple-parametric Magnetic Resonance Images Using Convolutional Neural Networks - Tzu-Hsuan Huang; Wei-Kai Lee; Chih-Chun Wu; Cheng-Chia Lee; Chia-Feng Lu; Huai-Che Yang; Chun-Yi Lin; Wen-Yuh Chung; Po-Shan Wang; Yen-Ling Chen; Hsiu-Mei Wu; Wan-You Guo; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose The first step in typical treatment of vestibular schwannoma (VS) is to localize the tumor region, which is time-consuming and subjective because it relies on repeatedly reviewing different parametric magnetic resonance (MR) images. A reliable, automatic VS detection method can streamline the process. Methods A convolutional neural network architecture, namely YOLO-v2 with a residual network as a backbone, was used to detect VS tumors from MR images. To heighten performance, T1-weighted–contrast-enhanced, T2-weighted, and T1-weighted images were combined into triple-channel images for feature learning. The triple-channel images were cropped into three sizes to serve as input images of YOLO-v2. The VS detection effectiveness levels were evaluated for two backbone residual networks that downsampled the inputs by 16 and 32. Results The results demonstrated the VS detection capability of YOLO-v2 with a residual network as a backbone model. The average precision was 0.7953 for a model with 416 × 416-pixel input images and 16 instances of downsampling, when both the thresholds of confidence score and intersection-over-union were set to 0.5. In addition, under an appropriate threshold of confidence score, a high average precision, namely 0.8171, was attained by using a model with 448 × 448-pixel input images and 16 instances of downsampling. Conclusion We demonstrated successful VS tumor detection by using a YOLO-v2 with a residual network as a backbone model on resized triple-parametric MR images. The results indicated the influence of image size, downsampling strategy, and confidence score threshold on VS tumor detection.

Characterization Of Secondary Metabolites From The Rhizome Of Cynara Scolymus And Their Antioxidant Properties - Chia-Lin Lee; Kuo-Chen Liao; Chien-Chih Chen; Yen-An Lin; Tung-Ying Wu; Yun-Lian Jhan; Chao-Jung Chen; Juan-Cheng Yang; Yang-Chang Wu (Natural Product Research, 2021)

Determination of Similarity Cutoff Value for the Classification of Macrobenthic Communities in the Korean Coast - Jae-Won Yoo; Chae-Lin Lee; Sungtae Kim; Su-Young Jeong; Chang-Gun Lee; Byoung-Seol Koh; Sang-Ock Ryu (Ocean Science Journal, 2021)

Molecular Imaging for Radiolabeling a PSMA-Targeted Long Circulating Peptide as a Theranostic Agent in Mice Bearing a Human Prostate Tumor - Ming-Hsin Li; Sheng-Nan Lo; Ming-Wei Chen; Wei-Lin Lo; Yuan-Ruei Huang; Shih-Ying Lee; Su-Jung Chen; Shih-Wei Lo; Shih-Ming Wang; Chih-Hsien Chang (Journal of Medical and Biological Engineering, 2021)

Comparing the cost, glycaemic control and medication adherence of utilizing patients’ own medicines (POMs) versus usual dispensing among diabetic patients in an outpatient setting - Phei Ching Lim; Yin Ying Chung; Shien Joo Tan; Te Ying Wong; Durga Devi Permalu; Thean Kheng Cheah; Shueh Lin Lim; Chong Yew Lee (DARU Journal of Pharmaceutical Sciences, 2021)

Human endothelial colony-forming cells provide trophic support for pluripotent stem cell-derived cardiomyocytes via distinctively high expression of neuregulin-1 - Xuechong Hong; Nicholas Oh; Kai Wang; Joseph Neumeyer; Chin Nien Lee; Ruei-Zeng Lin; Breanna Piekarski; Sitaram Emani; Arin K. Greene; Ingeborg Friehs; Pedro J. del Nido; Juan M. Melero-Martin (Angiogenesis, 2021)

Does technology advancement reduce aggregate carbon dioxide emissions? Evidence from 66 countries with panel threshold regression model - Ruzi Li; Lin Lin; Lei Jiang; Yaobin Liu; Chien-Chiang Lee (Environmental Science and Pollution Research, 2021)

Tracing the origins of recent Queensland fruit fly incursions into South Australia, Tasmania and New Zealand - Ángel-David Popa-Báez; Siu Fai Lee; Heng Lin Yeap; Guy Westmore; Peter Crisp; Dongmei Li; Renee Catullo; Emilie C. Cameron; Owain R. Edwards; Phillip W. Taylor; John G. Oakeshott (Biological Invasions, 2021)

Phylogeny, recombination, and invasiveness of group B Streptococcus revealed by genomic comparisons of its global strains - Enze Lin; Shengmei Zou; Yue Wang; Chien-Chung Lee; Cheng-Hsun Chiu; Ye Feng (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Anti-cancer strategies targeting the autotaxin-lysophosphatidic acid receptor axis: is there a path forward? - Gábor Tigyi; Mélanie A. Dacheux; Kuan-Hung Lin; Junming Yue; Derek Norman; Zoltán Benyó; Sue Chin Lee (Cancer and Metastasis Reviews, 2021)

Improvement of Two-Dimensional Flow-Depth Prediction Based on Neural Network Models By Preprocessing Hydrological and Geomorphological Data - Pin-Chun Huang; Kuo-Lin Hsu; Kwan Tun Lee (Water Resources Management, 2021)

The novel three-dimensional pulse images analyzed by dynamic L-cube polynomial model - Ching-Hsing Luo; Zhan Zhang; Bo Peng; Xiaohua Xie; Tsung-Lin Lee; Liang-Miin Tsai (Medical & Biological Engineering & Computing, 2021)

Direct Calculation Method for the Analysis of Non-linear Behavior of Ground-Support Interaction of a Circular Tunnel Using Convergence Confinement Approach - Yu-Lin Lee; Wen-Kuei Hsu; Chi-Min Lee; Yi-Xian Xin; Bo-Yu Zhou (Geotechnical and Geological Engineering, 2021)

Fine-scale roadkill risk models: understanding the intersection of wildlife and roads - Kristina Chyn; Te-En Lin; David P. Wilkinson; James L. Tracy; A. Michelle Lawing; Lee A. Fitzgerald (Biodiversity and Conservation, 2021)

Differential time-lag effects of ambient PM2.5 and PM2.5-bound PAHs on asthma emergency department visits - Shih-Chang Hsu; Jer-Hwa Chang; Chon-Lin Lee; Wen-Cheng Huang; Yuan-Pin Hsu; Chung-Te Liu; Shio-Shin Jean; Shau-Ku Huang; Chin-Wang Hsu (Environmental Science and Pollution Research, 2020)

Modeling oil dispersion under breaking waves. Part II: Coupling Lagrangian particle tracking with population balance model - Fangda Cui; Lin Zhao; Cosan Daskiran; Thomas King; Kenneth Lee; Joseph Katz; Michel C. Boufadel (Environmental Fluid Mechanics, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Public Perceptions of Mangrove Forests Matter for Their Conservation - Farid Dahdouh-Guebas; Gordon N. Ajonina; A. Aldrie Amir; Dominic A. Andradi-Brown; Irfan Aziz; Thorsten Balke; Edward B. Barbier; Stefano Cannicci; Simon M. Cragg; Marília Cunha-Lignon; David J. Curnick; Carlos M. Duarte; et al. (Frontiers in Marine Science, 2020)

Correction to: Complete genome sequences of two novel dicistroviruses detected in yellow crazy ants (Anoplolepis gracilipes) - Chih-Chi Lee; Chun-Yi Lin; Hung-Wei Hsu; Chin-Cheng Scotty Yang (Archives of Virology, 2020)

Complete genome sequences of two novel dicistroviruses detected in yellow crazy ants (Anoplolepis gracilipes) - Chih-Chi Lee; Chun-Yi Lin; Hung-Wei Hsu; Chin-Cheng Scotty Yang (Archives of Virology, 2020)

Intrusion of Kuroshio Helps to Diminish Coastal Hypoxia in the Coast of Northern South China Sea - Hon-Kit Lui; Chen-Tung Arthur Chen; Wei-Ping Hou; Jian-Ming Liau; Wen-Chen Chou; You-Lin Wang; Chau-Ron Wu; Jay Lee; Yi-Chia Hsin; Yan-Yu Choi (Frontiers in Marine Science, 2020)

Infusion of Human Mesenchymal Stem Cells Improves Regenerative Niche in Thioacetamide-Injured Mouse Liver - Ying-Hsien Kao; Yu-Chun Lin; Po-Huang Lee; Chia-Wei Lin; Po-Han Chen; Tzong-Shyuan Tai; Yo-Chen Chang; Ming-Huei Chou; Chih-Yang Chang; Cheuk-Kwan Sun (Tissue Engineering and Regenerative Medicine, 2020)

LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer’s disease - Chia-Hao Fan; Chia-Wei Lin; Hei-Jen Huang; Guey-Jen Lee-Chen; Ying-Chieh Sun; Wenwei Lin; Chiung-Mei Chen; Kuo-Hsuan Chang; Ming-Tsan Su; Hsiu Mei Hsieh-Li (Psychopharmacology, 2020)

Mild acidity likely accelerates the physiological matriptase autoactivation process: a comparative study between spontaneous and acid-induced matriptase zymogen activation - Bailing Jia; Hamishi A. Thompson; Robert B. Barndt; Yi-Lin Chiu; Mon-Juan Lee; See-Chi Lee; Jehng-Kang Wang; Hung-Jen Tang; Chen-Yong Lin; Michael D. Johnson (Human Cell, 2020)

Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin - Shun-Cheng Chang; Chien-Ping Chiang; Chih-Hsin Lai; Po-Wen A. Du; Yu-Sin Hung; Yu-Hsuan Chen; Hui-Yu Yang; Hao-Yu Fang; Shiao-Pieng Lee; Hung-Jen Tang; Jehng-Kang Wang; Michael D. Johnson; et al. (Human Cell, 2020)

Vulnerability and ecological footprint: a comparison between urban Taipei and rural Yunlin, Taiwan - Yung-Jaan Lee; Shih-Ying Lin (Environmental Science and Pollution Research, 2020)

On the Sensitivity of Typhoon Wave Simulations to Tidal Elevation and Current - Shih-Chun Hsiao; Han-Lun Wu; Wei-Bo Chen; Chih-Hsin Chang; Lee-Yaw Lin (Journal of Marine Science and Engineering, 2020)
The sensitivity of storm wave simulations to storm tides and tidal currents was investigated using a high-resolution, unstructured-grid, coupled circulation-wave model (Semi-implicit Cross-scale Hydroscience Integrated System Model Wind Wave Model version III (SCHISM-WWM-III)) driven by two typhoon events (Typhoons Soudelor and Megi) impacting the northeastern coast of Taiwan. Hourly wind fields were acquired from a fifth-generation global atmospheric reanalysis (ERA5) and were used as meteorological conditions for the circulation-wave model after direct modification (MERA5). The large typhoon-induced waves derived from SCHISM-WWM-III were significantly improved with the MERA5 winds, and the peak wave height was increased by 1.0–2.0 m. A series of numerical experiments were conducted with SCHISM-WWM-II and MERA5 to explore the responses of typhoon wave simulations to tidal elevation and current. The results demonstrate that the simulated significant wave height, mean wave period and wave direction for a wave buoy in the outer region of the typhoon are more sensitive to the tidal current but less sensitive to the tidal elevation than those for a wave buoy moored in the inner region of the typhoon. This study suggests that the inclusion of the tidal current and elevation could be more important for typhoon wave modeling in sea areas with larger tidal ranges and higher tidal currents. Additionally, the suitable modification of the typhoon winds from a global atmospheric reanalysis is necessary for the accurate simulation of storm waves over the entire region of a typhoon.

Lactobacillus plantarum PS128 Ameliorated Visceral Hypersensitivity in Rats Through the Gut–Brain Axis - Yen-Wenn Liu; Yen-Po Wang; Hsu-Fang Yen; Pei-Yi Liu; Wen-Jian Tzeng; Chia-Fen Tsai; Han-Chieh Lin; Fa-Yauh Lee; One-Jang Jeng; Ching-Liang Lu; Ying-Chieh Tsai (Probiotics and Antimicrobial Proteins, 2020)