Autophagy modulation in resveratrol protective effects on steroidogenesis in high-fat diet-fed mice and H2O2-challenged TM3 cells - Ping Wang; Mengyu Lin; Chao Chen; Zheng-mei Lv (Molecular Biology Reports, 2022)

Effects of Meranzin Hydrate On the LncRNA–miRNA–mRNA Regulatory Network in the Hippocampus of a Rat Model of Depression - Kechao Nie; Lin Liu; Luqi Peng; Mei Zhang; Chunhu Zhang; Bo Xiao; Zian Xia; Wei Huang (Journal of Molecular Neuroscience, 2022)

Genetic diversity and population structure of Curcuma alismatifolia Gagnep. accessions revealed by SSR markers - Hui-Wen Yu; Ling-Jun Ke; Yi-Lan Xiao; Si-Jia Chen; Yuan-Yuan Li; Qi-Lin Tian; Yun-He Li; Jin-Shui Lin; Luan-Mei Lu (Genetic Resources and Crop Evolution, 2022)

Alternaria species causing leaf spot on hemp (Cannabis sativa) in Northern China - Hong Cheng; Lin Zhao; Xin Wei; Xi Liu; Guo-Yang Gao; Jian-Xin Deng; Mei-Jia Li (European Journal of Plant Pathology, 2022)

Spatiotemporal characteristics and influencing factors of agricultural eco-efficiency in Jilin agricultural production zone from a low carbon perspective - Yanhua Guo; Lianjun Tong; Lin Mei (Environmental Science and Pollution Research, 2022)

Duration of Induced Metallothionein is a Critical Factor in the Cadmium-Resistance Among Goldfish (Carassius auratus) and Common Carp (Cyprinus carpio) - Feng Ming Chang; Chia Hao Lin; Su Mei Wu (Bulletin of Environmental Contamination and Toxicology, 2022)

Investigation on grouting diffusion in inclined fracture with flowing water conditions - Jia-fan Zhang; Xun-xun Chen; Yang Liu; Hui-mei Zhang; Chun-lin Wang; Gang Fang (Arabian Journal of Geosciences, 2022)

The management of bone defect using long non-coding RNA as a potential biomarker for regulating the osteogenic differentiation process - Jia-lin Liu; Yan-shi Liu; Mei-jie Zheng; Hui-yu He (Molecular Biology Reports, 2022)
Tissue engineered bone brings hope to the treatment of bone defects, and the osteogenic differentiation of stem cells is the key link. Inducing osteogenic differentiation of stem cells may be a potential approach to promote bone regeneration. In recent years, lncRNA has been studied in the field increasingly, which is believed can regulate cell cycle, proliferation, metastasis, differentiation and immunity, participating in a variety of physiology and pathology processes. At present, it has been confirmed that certain lncRNAs regulate the osteogenesis of stem cells and take part in mediating signaling pathways including Wnt/β-catenin, MAPK, TGF-β/BMP, and Notch pathways. Here, we provided an overview of lncRNA, reviewed its researches in the osteogenic differentiation of stem cells, emphasized the importance of lncRNA in bone regeneration, and focused on the roles of lncRNA in signaling pathways, in order to make adequate preparations for applying lncRNA to bone tissue Engineering, letting it regulate the osteogenic differentiation of stem cells for bone regeneration.

Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis - Zhuo-Zhi Liang; Yi-Xin Zhang; Rui-Mei Zhu; Yue-Lin Li; Hong-Mei Jiang; Ruo-Bi Li; Qian-Xin Chen; Qing Wang; Lu-Ying Tang; Ze-Fang Ren (Environmental Science and Pollution Research, 2022)

A bi-scale assessing framework for aesthetic ecosystem services of villages in a world heritage site - Yin-ping Ding; Zhi-lin Liu; Yuan-mei Jiao; Qiu-e Xu; Kan-feng Zhang; Cheng-jing Liu; Fan Chen (Journal of Mountain Science, 2022)

Description of Aureibaculum luteum sp. nov. and Aureibaculum flavum sp. nov. isolated from Antarctic intertidal sediments - Xiao-yan He; Ning-hua Liu; Chao-yi Lin; Mei-ling Sun; Xiu-lan Chen; Yu-zhong Zhang; Yu-qiang Zhang; Xi-ying Zhang (Antonie van Leeuwenhoek, 2022)

Morphological and Molecular Characterization of Paragonimus skrjabini Complex from Yunnan, China: A Brief Report - Qiu-Hong Shu; Shu-De Li; Ming Tian; Yong Meng; Shu-Mei-Qi He; Min Zhu; Miao-Miao Wang; Wen-Lin Wang (Acta Parasitologica, 2022)
Purpose To perform environmental sampling and molecular identification of Paragonimus in endemic regions, which may help in minimizing transmission among humans. Methods Mountain crabs from the genus Potamiscus were collected and the encysted metacercariae were extracted and subjected to morphological identification, followed by animal inoculation in Sprague–Dawley (SD) rats. After 112 days of infection, animals were killed and adult worms were extracted from lungs and muscles. The morphology of adult worms was characterized by microscopy and molecular identification was done by polymerase chain reaction, followed by sequencing of cox1 and ITS2 genes. Phylogenetic analysis was done by maximum parsimony method. Results A total of 447 crabs were captured from the streams of Tongchang Town, Jinping County, Yunnan Province, China. The infection rate was found to be 41% (186 out of 447 crabs). The metacercariae of Paragonimus skrjabini was identified by the characteristics round or spherical encysted form measuring 410 to 460 × 400 to 460 µm. After animal infection in SD rats, adults were presumptively confirmed to be P. skrjabini , which was also confirmed by gene amplification and sequence analysis of cox1 and ITS2 regions. Paragonimus skrjabini clustered with previously reported P. skrjabini from Yunnan and Vietnam. The confidence values of their branches were > 95%. Phylogenetic analysis of the ITS2 region revealed two distinct clusters with distinct geographical grouping. Phylogenetic analysis with the combined data sets reiterated the geographical grouping with P. skrjabini from Yunnan clustering with strains from Vietnam. Conclusion Metacercariae of P. skrjabini was discovered in freshwater crabs in Yunnan province, China, and the strains were phylogenetically related to P. skrjabini from Vietnam.

A Challenge to Conventional Fish Meal: Effects of Soy Protein Peptides on Growth, Histomorphology, Lipid Metabolism and Intestinal Health for Juvenile Pompano Trachinotus ovatus - Huaxing Lin; Beiping Tan; Gyan Watson Ray; Min Zeng; Mei Li; Shuyan Chi; Qihui Yang (Frontiers in Marine Science, 2022)
This experiment was conducted to assess the possibility of replacing fish meal (FM) with soy protein peptide (SPP) at different levels—0% (FM), 14.29% (S5), 28.57% (S10), 57.14% (S20), 71.42%(S25)—and its effects on growth, histology, gene expression related to liver lipid metabolism and intestinal immunity in juvenile pompano Trachinotus ovatus (initial mean weight = 39.88 ± 0.15 g). 600 healthy and uniformed-size fish were distributed to five groups of three replicates, each with 40 fish in each floating cage and fed twice daily for 8 weeks. Results showed that no significant difference in the growth was observed with SPP replacing FM ( P > 0.05). Serum glutathione peroxidase activity in the S10 group was significantly higher than that in the FM group, and serum malondialdehyde content significantly decreased ( P < 0.05). SPP significantly improved intestinal immunity by increasing alkaline phosphatase and lysozyme activities and up-regulating interleukin 10 and complement 4 mRNA levels while simultaneously decreasing triglyceride and total cholesterol content and down-regulating interleukin 1β mRNA expression. Villus length and muscle thickness in the S10 group were significantly higher than those in the FM group ( P < 0.05). SPP significantly improved liver fat metabolism by increasing carnitine palmitoyl transferase I mRNA levels, and down-regulating fatty acid synthesis mRNA expression ( P < 0.05). In summary, SPP substitution for FM promoted intestinal health, liver lipid metabolism and reduced liver fat accumulation for juvenile pompano T. ovatus , with no significant effect on growth performance. Based on the second-order polynomial analysis model of LYZ activity, the optimal replacement SPP level for juvenile pompano T. ovatus was 11.82%.

L-Theanine Ameliorated Rotenone-Induced Parkinsonism-like Symptoms in Rats - Cheng-Neng Chen; Mao-Hsien Wang; Hung-Sheng Soung; Shu-Mei Chen; Chih-Hsiang Fang; Yi-Wen Lin; Hsiang-Chien Tseng (Neurotoxicity Research, 2022)

Oxygen Metabolism-induced Stress Response Underlies Heart–brain Interaction Governing Human Consciousness-breaking and Attention - Xiao-Juan Xue; Rui Su; Ze-Feng Li; Xiao-Ou Bu; Peng Dang; Si-Fang Yu; Zhi-Xin Wang; Dong-Mei Chen; Tong-Ao Zeng; Ming Liu; Hai-Lin Ma; De-Long Zhang (Neuroscience Bulletin, 2022)

Synthesis, antifungal activity and 3D-QSAR study of novel acyl thiourea compounds containing gem-dimethylcyclopropane ring - Mei Huang; Min Huang; Xiu Wang; Wen-Gui Duan; Gui-Shan Lin; Fu-Hou Lei (Molecular Diversity, 2022)

Effect of different colored net-house conditions on life table parameters of the diamondback moth, Plutella xylostella L. (Lepidoptera: Plutellidae), on broccoli (Brassica oleracea L. var. italica) - Prashanth Kumar Senthilkumar; Mei-ying Lin; Chinniah Chinniah; Ramasamy Srinivasan; Paola Sotelo-Cardona (International Journal of Tropical Insect Science, 2022)

Changes in the growth performance, antioxidant enzymes and stress resistance caused by dietary administration of synbiotic (fructooligosaccharide and probiotics) in juvenile Chinese Mitten Crab, Eriocheir sinensis - Jin-Juan Wan; Jian-lin Pan; Mei-Fang Shen; Hui Xue; Meng-lin Sun; Mei-Qin Zhang; Xi-He Zhu; Xing-kong Ma (Aquaculture International, 2022)

Development and validation of a 30-day death nomogram in patients with spontaneous cerebral hemorrhage: a retrospective cohort study - Qian Han; Mei Li; Dongpo Su; Aijun Fu; Lin Li; Tong Chen (Acta Neurologica Belgica, 2022)

Current Dependent Dispersal Characteristics of Japanese Glass Eel around Taiwan - Kuan-Mei Hsiung; Yen-Ting Lin; Yu-San Han (Journal of Marine Science and Engineering, 2022)
Japanese eel larvae are passively transported to the East Asian Continental Shelf by the North Equatorial Current, Kuroshio and Kuroshio intrusion currents, and coastal currents. Previous studies have investigated the dispersal characteristics and pathways of Japanese glass eels. However, there are still limitations in these studies. According to long-term (2010–2020) catch data from the Fisheries Agency in Taiwan, the distribution and time series of glass eels recruitment to Taiwan are closely related to the surrounding ocean currents. Recruitment begins in eastern Taiwan via the mainstream Kuroshio and in southern Taiwan via the Taiwan Strait Warm Current. In central Taiwan, recruitment occurs from southern Taiwan, as well as from mainland China via the southern branch of the China Coast Current (CCC). The latest recruitment occurred in northern Taiwan and mainly comprised glass eels from mainland China via the northern branch of the CCC. A stronger monsoon during the La Niña phase could affect the recruitment time series in northern and eastern Taiwan. This study suggests that the recruitment directionality of glass eels is an indicator of the flow field of ocean/coastal currents and elucidates the dispersal characteristics of glass eels in the waters around Taiwan.

Historical Connectivity and Demography of the Ferocious Reef Crab, Eriphia ferox (Crustacea; Eriphiidae), Demonstrate That Taoyuan Algal Reef Is an Essential Population Source Along the East Taiwan Strait - Mu-Han Chen; Ya-Yi Huang; Bi-Ying Huang; Hernyi Justin Hsieh; Jen Nie Lee; Mei Lin Neo; Hironobu Fukami; Chaolun Allen Chen (Frontiers in Marine Science, 2022)
The east Taiwan Strait is largely fringed by sandy and muddy habitats. However, a massive algal reef made of crustose coralline algae has been found along the coast off Taoyuan city in northwestern Taiwan. The porous structure of Taoyuan Algal Reef harbors high abundance and diversity in marine organisms, including the ferocious reef crab, Eriphia ferox . Such a pivotal geographic location and unique ecological features make Taoyuan Algal Reef a potential stepping stone connecting biotic reefs in the east Taiwan Strait, South China Sea to the south, and even the high latitude of Japan to the north. In this study, we examined the population connectivity and historical demography of E. ferox by analyzing mitochondrial cytochrome oxidase I (COI) fragments of 317 individuals sampled from 21 localities in the northwestern Pacific. Our analyses of haplotype network and pairwise F ST comparisons revealed a lack of phylogeographical structure among E. ferox populations, implying the existence of a migration corridor connecting the South and East China Seas through the east Taiwan Strait. Multiple lines of evidence, including significant values in neutrality tests, unimodally shaped mismatch distributions, and Bayesian skyline plots elucidated the rapid population growth of E. ferox following the sea-level rise after Last Glacial Maximum (ca. 2–10 Ka). Such demographic expansion in E. ferox coincided with the time when Taoyuan Algal Reef started to build up around 7,500 years ago. Coalescent migration analyses further indicated that the large and continuous E. ferox population exclusively found in Datan Algal Reef, the heart of Taoyuan Algal Reef, was a source population exporting migrants both northward and southward to the adjacent populations. The bidirectional gene flow should be attributed to larval dispersal by ocean currents and secondary contact due to historical population expansion. Instead of serving as a stepping stone, our results support that Taoyuan Algal Reef is an essential population source for biotic reef-associated species along the east Taiwan Strait, and highlight the importance of conserving such a unique ecosystem currently threatened by anthropogenic development.

Distribution of Coomassie Blue Stainable Particles in the Pearl River Estuary, China, Insight Into the Nitrogen Cycling in Estuarine System - Cui-Ci Sun; Wei-Zhong Yue; You-Shao Wang; Wei-Hong He; Yi-Guo Hong; Fu-Lin Sun; Hao Cheng; Mei-Lin Wu; Zhao-Yu Jiang; Fei Jiao; Yu-Tu Wang (Frontiers in Marine Science, 2022)
Distributions of Coomassie Blue stainable particles (CSP), the sources and transports, as well as their implications for nitrogen biogeochemical cycles in the Pearl River estuary (PRE) were investigated during two cruises in August 2016 and January 2017. CSP color concentrations (CSP concentration determined spectrophotometrically) were 73.7–685.3 μg BSA eq L –1 [μg Bovine serum albumin (BSA) equivalent liter –1 ] in August 2016 and 100.6–396.4 μg BSA eq L –1 in January 2017, respectively. CSP concentrations were high in low-salinity waters (<5), and declined from the river to the middle estuary by 80% in the wet season and 55.6% in the dry season, respectively, then increased again in the lower estuary due to high primary production. CSP concentrations were mainly associated with chlorophyll a (Chl a ) concentration except for the turbid mixing zone, suggesting that autochthonous phytoplankton production served as the primary source of CSP in the PRE. The concentrations of nitrogen (N) as CSP in the PRE were comparable to the nitrogen content of particulate hydrolysable amino acids (PHAA). Pictures of CSP taken by microscopy and the correlation between composition of PHAA and the ratio of Chl a /CSP color showed that CSP were relatively degraded due to delivery of old terrestrial protein to river section and extensive microbial degradation during mixing at the upper and middle parts of the estuary, whereas CSP in lower estuary appeared to be more labile due to higher fresh algal production. The contribution of CSP nitrogen (CSP-N) to the particulate nitrogen (PN) pool was 34.98% in summer and 30.8% in winter. The conservative estimate of CSP-N input flux in the Pearl River Delta was about 6 × 10 6 mol N d –1 . These results suggested that CSP was a significant pool of organic nitrogen in the PRE. The study of CSP composition in terms of nitrogen provides new insight into the roles of CSP on nitrogen biogeochemical processes in the turbid and productive estuarine system.

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Genome-wide identification and expression analysis of glycosyltransferase gene family 1 in Quercus robur L. - Jie Zhang; Li-Mei Lin; Wen-Wen Cheng; Xin Song; Yue-Hong Long; Zhao-Bin Xing (Journal of Applied Genetics, 2021)

Feasibility and utility of facemask sampling in the detection of SARS-CoV-2 during an ongoing pandemic - Dorothy Hui Lin Ng; Mei Yi Sim; Hong Hong Huang; Jean Xiang Ying Sim; Jenny Guek Hong Low; Jay Kheng Sit Lim (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Analysis of the starch properties in tetraploid wheat–Aegilops sharonensis amphidiploid - Qing Li; Xuteng Zhang; Na Lin; Guzmán Carlos; Jingyu Lan; Huaping Tang; Pengfei Qi; Jian Ma; Jirui Wang; Guoyue Chen; Wei Li; Zhien Pu; et al. (Cereal Research Communications, 2021)

Long-term changes of water acidity in an intact forested watershed in south China - Xiao-dong Liu; Ying-jie Feng; Qi-feng Mo; Guo-wei Chu; Yue-lin Li; Qian-mei Zhang; Wei-qiang Zhang; Xian-hua Gan; Qing Zhou (Journal of Mountain Science, 2021)

Influence of biochar amendment on stormwater management in green roofs: experiment with numerical investigation - Lin Gan; Ankit Garg; Hao Wang; Guoxiong Mei; Jiaqin Liu (Acta Geophysica, 2021)

Characterization and identification of SFDC ‐1, a novel AmpC ‐type β‐lactamase in Serratia fonticola - Xu Dong; Peiyao Zhang; Kexin Zhou; Jialei Liang; Qiaoling Li; Xueya Zhang; Danying Zhou; Wei Lu; Zhewei Sun; Hongmao Liu; Junwan Lu; Xi Lin; et al. (Environmental Microbiology, 2021)
Summary The clinical and environmental infections caused by AmpC β‐lactamases have been increasingly reported recently. In this study, we characterize the novel chromosome‐encoded AmpC β‐lactamase SFDC‐1 identified in Serratia fonticola strain R28, which was isolated from a rabbit raised on a farm in southern China. SFDC‐1 shared the highest amino acid identity of 79.6% with the functionally characterized AmpC β‐lactamase gene bla YRC‐1 , although it had highly homologous functionally uncharacterized relatives in the same species from different sources, including some of the clinical significance. The cloned bla SFDC‐1 exhibited resistance to a broad spectrum of β‐lactam antibiotics, including most cephalosporins with the highest resistance to ampicillin, cefazolin and ceftazidime, with increased MIC levels ≥128‐fold compared with the control strains. The purified SFDC‐1 showed catalytic activities against β‐lactams with the highest catalytic activity to cefazolin. The genetic context of bla SFDC‐1 and its relatives was conserved in the chromosome, and no mobile genetic elements were found surrounding them.

Chemical constituents from the barks of Melia azedarach and their PTP1B inhibitory activity - Sheng-Nan Zhang; Lin Huang; Rui-Jing Ma; Mei-Feng Yang; Ben-Fu Wei; Hong-Zhi Song; Heng-Shan Wang; Qin-Gang Tan (Natural Product Research, 2021)

Cardiovascular safety of long-term anti-obesity drugs in subjects with overweight or obesity: a systematic review and meta-analysis - Lin Zhang; Zhi Liu; Shenling Liao; He He; Mei Zhang (European Journal of Clinical Pharmacology, 2021)

Associations between air pollution exposure and birth defects: a time series analysis - Shu Sun; Qi Zhang; Xinmiao Sui; Liu Ding; Jie Liu; Mei Yang; Qihong Zhao; Chao Zhang; Jiahu Hao; Xiujun Zhang; Shilei Lin; Rui Ding; et al. (Environmental Geochemistry and Health, 2021)

Bacterial community variations in the South China Sea driven by different chemical conditions - Fu-lin Sun; You-Shao Wang; Mei-Lin Wu; Cui-Ci Sun; Zhao-Yu Jiang; Hao Cheng; Jiao Fei (Ecotoxicology, 2021)

Effects of organic matter on the distribution of rare earth elements in red soil aggregates during ecological restoration - Xiao-lin Ou; Zhi-biao Chen; Zhi-qiang Chen; Mei-xia Liang; Hai-bin Chen (Journal of Mountain Science, 2021)

Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice - Lin Chen; Shu-Yu Ren; Rui-Xue Li; Kun Liu; Jing-Fei Chen; Yu-Jian Yang; Yong-Bin Deng; Han-Zhi Wang; Lan Xiao; Feng Mei; Fei Wang (Neuroscience Bulletin, 2021)
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths ( NG2-CreER TM ; Tau-mGFP ), we found that myelinogenesis was highly active in most brain regions, such as the motor cortex and corpus callosum. After exposure to hypoxia (10% oxygen) 12 h per day for 4 weeks, myelinogenesis was largely inhibited in the 4-month old brain and the mice displayed motor coordination deficits revealed by the beam-walking test. To determine the relationship between the inhibited myelination and functional impairment, we induced oligodendroglia-specific deletion of the transcription factor Olig2 by tamoxifen ( NG2-CreER TM ; Tau-mGFP; Olig2 fl/fl ) in adult mice to mimic the decreased myelinogenesis caused by hypoxia. The deletion of Olig2 inhibited myelinogenesis and consequently impaired motor coordination, suggesting that myelinogenesis is required for motor function in adult mice. To understand whether enhancing myelination could protect brain functions against hypoxia, we treated hypoxic mice with the myelination-enhancing drug-clemastine, which resulted in enhanced myelogenesis and improved motor coordination. Taken together, our data indicate that chronic hypoxia inhibits myelinogenesis and causes functional deficits in the brain and that enhancing myelinogenesis protects brain functions against hypoxia-related deficits.

Depression Augments Plasma APOA4 without Changes of Plasma Lipids and Glucose in Female Adolescents Carrying G Allele of APOA4 rs5104 - Qi Wei Guo; Yan Jun Si; Yi Lin Shen; Xu Chen; Mei Yang; Ding Zhi Fang; Jia Lin (Journal of Molecular Neuroscience, 2021)

A new species of Macandrewia (Demospongiae, Tetractinellida, Macandrewiidae) from a seamount in the Western Pacific Ocean - Lin Gong; Swee-Cheng Lim; Mei Yang; Xinzheng Li (Journal of Oceanology and Limnology, 2021)

Multifunctional graphene-based nanocomposites for simultaneous enhanced photocatalytic degradation and photothermal antibacterial activity by visible light - Ya-kun Lv; Lin Mei; Liu-xue Zhang; De-hong Yang; Zi-yu Yin (Environmental Science and Pollution Research, 2021)

Future variation in mountainous discharge in arid northwestern China: A basin case study - Lei Wu; Chang-bin Li; Xu-hong Xie; Jia-nan Lv; Jian-mei Wei; Xuan Zhou; Lin-shan Yang (Journal of Mountain Science, 2021)

Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination - Kun Liu; Bin Yu; Jing-Fei Chen; Rui-Xue Li; Lin Chen; Shu-Yu Ren; Fei Wang; Feng Mei; Lan Xiao (Neuroscience Bulletin, 2021)
Increasing evidence has shown that astrocytes are implicated in regulating oligodendrocyte myelination, but the underlying mechanisms remain largely unknown. To understand whether microRNAs in astrocytes function in regulating oligodendroglial differentiation and myelination in the developing and adult CNS, we generated inducible astrocyte-specific Dicer conditional knockout mice (hGFAP-CreERT; Dicer fl/fl). By using a reporter mouse line (mT/mG), we confirmed that hGFAP-CreERT drives an efficient and astrocyte-specific recombination in the developing CNS, upon tamoxifen treatment from postnatal day 3 (P3) to P7. The Dicer deletion in astrocytes resulted in inhibited oligodendroglial differentiation and myelination in the developing CNS of Dicer cKO mice at P10 and P14, and did not alter the densities of neurons or axons, indicating that Dicer in astrocytes is required for oligodendrocyte myelination. Consequently, the Dicer deletion in astrocytes at P3 resulted in impaired spatial memory and motor coordination at the age of 9 weeks. To understand whether Dicer in astrocytes is also required for remyelination, we induced Dicer deletion in 3-month-old mice and then injected lysolecithin into the corpus callosum to induce demyelination. The Dicer deletion in astrocytes blocked remyelination in the corpus callosum 14 days after induced demyelination. Together, our results indicate that Dicer in astrocytes is required for oligodendroglia myelination in both the developing and adult CNS.

Performance Comparison of the Deep Learning and the Human Endoscopist for Bleeding Peptic Ulcer Disease - Hsu-Heng Yen; Ping-Yu Wu; Pei-Yuan Su; Chia-Wei Yang; Yang-Yuan Chen; Mei-Fen Chen; Wen-Chen Lin; Cheng-Lun Tsai; Kang-Ping Lin (Journal of Medical and Biological Engineering, 2021)
Purpose Management of peptic ulcer bleeding is clinically challenging. Accurate characterization of the bleeding during endoscopy is key for endoscopic therapy. This study aimed to assess whether a deep learning model can aid in the classification of bleeding peptic ulcer disease. Methods Endoscopic still images of patients ( n = 1694) with peptic ulcer bleeding for the last 5 years were retrieved and reviewed. Overall, 2289 images were collected for deep learning model training, and 449 images were validated for the performance test. Two expert endoscopists classified the images into different classes based on their appearance. Four deep learning models, including Mobile Net V2, VGG16, Inception V4, and ResNet50, were proposed and pre-trained by ImageNet with the established convolutional neural network algorithm. A comparison of the endoscopists and trained deep learning model was performed to evaluate the model’s performance on a dataset of 449 testing images. Results The results first presented the performance comparisons of four deep learning models. The Mobile Net V2 presented the optimal performance of the proposal models. The Mobile Net V2 was chosen for further comparing the performance with the diagnostic results obtained by one senior and one novice endoscopists. The sensitivity and specificity were acceptable for the prediction of “normal” lesions in both 3-class and 4-class classifications. For the 3-class category, the sensitivity and specificity were 94.83% and 92.36%, respectively. For the 4-class category, the sensitivity and specificity were 95.40% and 92.70%, respectively. The interobserver agreement of the testing dataset of the model was moderate to substantial with the senior endoscopist. The accuracy of the determination of endoscopic therapy required and high-risk endoscopic therapy of the deep learning model was higher than that of the novice endoscopist. Conclusions In this study, the deep learning model performed better than inexperienced endoscopists. Further improvement of the model may aid in clinical decision-making during clinical practice, especially for trainee endoscopist.

Evaluation of the RNA extraction methods in different Ginkgo biloba L. tissues - Xiao-lin Zhang; Xiao-li Huang; Jia Li; Mei Mei; Wan-qi Zeng; Xiu-jun Lu (Biologia, 2021)

Coupling effects of hydrological characteristics and nutrient load in sediments on the trophic state of reservoirs - Fan Xinyi; Yue Yihong; Mei Lin; Li Xiaoying; Hu Zhehui; Luo Jiajie; Liu Liu; Wang Fushun (Acta Geochimica, 2021)

A new ent -kaurane diterpene from Isodon henryi - Xue Jiang; Ling-Xia Zhang; Qing-Mei Feng; Hong Wu; Ya-Lin Liu; De-Qin Wang; Li-Ping Dai; Zhi-Min Wang (Natural Product Research, 2021)

The Characteristic of Critical Genes in Neuroendocrine System and Their Regulation on Food Habit Transition and Metamorphosis of Veined Rapa Whelk Rapana venosa (Valenciennes, 1846) - Mei-Jie Yang; Jie Feng; Hao Song; Zheng-Lin Yu; Pu Shi; Jian Liang; Zhi Hu; Cong Zhou; Xiao-Lin Wang; Tao Zhang (Frontiers in Marine Science, 2021)
Metamorphosis is a critical developmental event in mollusks, and neuroendocrine system plays an essential role in this process. Rapana venosa is an economically important shellfish in China, but the artificial technology of R. venosa aquaculture is limited by metamorphosis. As a carnivorous gastropod, food habit transition makes the mechanism of R. venosa metamorphosis more complex. To investigate the changes in the neuroendocrine system and to reveal its role in regulating the food habit transition and metamorphosis of R. venosa , we cloned the cDNA sequences encoding 5-hydroxytryptamine receptor ( Rv-5HTR ), nitric oxide synthetase ( Rv-NOS ) and cholecystokinin receptor ( Rv-CCKR ), and investigated their expression by quantitative real-time PCR analysis, and explore the spatio-temporal changes of 5-HT protein expression using Immunohistochemical (IHC) analysis. The expression of the three geens was significantly increased in the early intramembrane veliger stage, which indicates that the three genes are related to the development of digestive system. Additionally, expression of the three genes was decreased after metamorphosis, while Rv-NOS and Rv-CCKR were increasingly expressed in competent larvae, which may help the larvae find suitable environments and promote digestive system development for metamorphosis, and the result of 5-HT IHC analysis also reflects the development of neuroendocrine system. Furthermore, results show that CCK can effect the expression of digestive enzyme, NOS and 5-HT receptor. Finally, based on the present results, we hypothesized that CCK and CCK receptor may be critical regulatory factors of food habit transition and metamorphosis. These results might provide information on the development of neuroendocrine system of R. venosa , and new insight into the regulation of the food habit transition and metamorphosis of gastropods.

Distribution, Temporal Change, and Conservation Status of Tropical Seagrass Beds in Southeast Asia: 2000–2020 - Kenji Sudo; T. E. Angela L. Quiros; Anchana Prathep; Cao Van Luong; Hsing-Juh Lin; Japar Sidik Bujang; Jillian Lean Sim Ooi; Miguel D. Fortes; Muta Harah Zakaria; Siti Maryam Yaakub; Yi Mei Tan; Xiaoping Huang; et al. (Frontiers in Marine Science, 2021)
Although Southeast Asia is a hotspot of global seagrass diversity, there are considerable information gaps in the distribution of seagrass beds. Broad-scale seagrass distribution has not been updated in the global seagrass database by UNEP-WCMC since 2000, although studies on seagrasses have been undertaken intensively in each region. Here we analyze the recent distribution of tropical seagrass beds, their temporal changes, causes of decline and conservation status in Southeast Asia (plus southern mainland China, Taiwan and Ryukyu Island of Japan) using data collected after 2000. Based on the 195 literature published since 2000, we identified 1,259 point data and 1,461 polygon data showing the distribution of seagrass beds. A large discrepancy was found in the seagrass bed distribution between our updated data and the UNEP-WCMC database, mostly due to inaccurate and low resolution location information in the latter. Temporal changes in seagrass bed area analyzed for 68 sites in nine countries/regions demonstrated that more than 60% of seagrass beds declined at an average rate of 10.9% year –1 , whereas 20% of beds increased at an average rate of 8.1% year –1 , leading to an overall average decline of 4.7% year –1 . Various types of human-induced threats were reported as causes for the decline, including coastal development, fisheries/aquaculture, and natural factors such as typhoons and tsunamis. The percentage of seagrass beds covered with existing marine protected areas (MPAs) varied greatly among countries/regions, from less than 1% in Brunei Darussalam and Singapore to 100% in southern Japan. However, the degree of conservation regulation was not sufficient even in regions with higher MPA coverage. The percentage of seagrass beds within EBSAs (Ecologically and Biologically Significant Area determined by the Convention of Biological Diversity) was higher than that within MPAs because EBSAs cover a greater area than MPAs. Therefore, designating EBSAs as legally effective MPAs can greatly improve the conservation status of seagrass beds in Southeast Asia.

A preliminary investigation of epibiotic macrofauna on the mangrove horseshoe crab Carcinoscorpius rotundicauda (Latreille, 1802) in Singapore - LIM Chin Sing; TAN Lester Jin Xiang; NEO Mei Lin; TEO Serena Lay Ming; BENG Stephen Sui Leung; NADARAJAN Saravanan; TUN Karenne (Marine Biology Research, 2021)

Detection of Vestibular Schwannoma on Triple-parametric Magnetic Resonance Images Using Convolutional Neural Networks - Tzu-Hsuan Huang; Wei-Kai Lee; Chih-Chun Wu; Cheng-Chia Lee; Chia-Feng Lu; Huai-Che Yang; Chun-Yi Lin; Wen-Yuh Chung; Po-Shan Wang; Yen-Ling Chen; Hsiu-Mei Wu; Wan-You Guo; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose The first step in typical treatment of vestibular schwannoma (VS) is to localize the tumor region, which is time-consuming and subjective because it relies on repeatedly reviewing different parametric magnetic resonance (MR) images. A reliable, automatic VS detection method can streamline the process. Methods A convolutional neural network architecture, namely YOLO-v2 with a residual network as a backbone, was used to detect VS tumors from MR images. To heighten performance, T1-weighted–contrast-enhanced, T2-weighted, and T1-weighted images were combined into triple-channel images for feature learning. The triple-channel images were cropped into three sizes to serve as input images of YOLO-v2. The VS detection effectiveness levels were evaluated for two backbone residual networks that downsampled the inputs by 16 and 32. Results The results demonstrated the VS detection capability of YOLO-v2 with a residual network as a backbone model. The average precision was 0.7953 for a model with 416 × 416-pixel input images and 16 instances of downsampling, when both the thresholds of confidence score and intersection-over-union were set to 0.5. In addition, under an appropriate threshold of confidence score, a high average precision, namely 0.8171, was attained by using a model with 448 × 448-pixel input images and 16 instances of downsampling. Conclusion We demonstrated successful VS tumor detection by using a YOLO-v2 with a residual network as a backbone model on resized triple-parametric MR images. The results indicated the influence of image size, downsampling strategy, and confidence score threshold on VS tumor detection.

A Review on the Emerging Asian Aquaculture Fish, the Malaysian Mahseer (Tor tambroides): Current Status and the Way Forward - Melinda Mei Lin Lau; Leonard Whye Kit Lim; Sairatul Dahlianis Ishak; Ambok Bolong Abol-Munafi; Hung Hui Chung (Proceedings of the Zoological Society, 2021)

Enhanced treatment of shale gas fracturing waste fluid through plant-microbial synergism - Bo Shao; Xu Tan; Ju-Long Li; Mei He; Lei Tian; Wen-Jie Chen; Yan Lin (Environmental Science and Pollution Research, 2021)

Proton Pump Inhibitor Exposure and Acute Myocardial Infarction Risk: A Nested Cohort Study - Hsiang-Jung Tseng; Chih-Ming Cheng; Shih-Jen Tsai; Wei-Chen Lin; Ya-Mei Bai; Chia-Fen Tsai; Tung-Ping Su; Cheng-Ta Li; Tzeng-Ji Chen; Mu-Hong Chen (Cardiovascular Toxicology, 2021)

Correction to: Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Cytotoxic p -terphenyls from the deep-sea-derived Aspergillus candidus - Yu-Kun Lin; Chun-Lan Xie; Cui-Ping Xing; Bao-Qu Wang; Xiao-Xue Tian; Jin-Mei Xia; Ling-Yun Jia; Ying-Ni Pan; Xian-Wen Yang (Natural Product Research, 2021)

Assessing ecological health of mangrove ecosystems along South China Coast by the pressure–state–response (PSR) model - Yu-Tu Wang; You-Shao Wang; Mei-Lin Wu; Cui-Ci Sun; Ji-Dong Gu (Ecotoxicology, 2021)

Sepsis and Cerebral Dysfunction: BBB Damage, Neuroinflammation, Oxidative Stress, Apoptosis and Autophagy as Key Mediators and the Potential Therapeutic Approaches - Ming Gu; Xiang-Lin Mei; Ya-Nan Zhao (Neurotoxicity Research, 2021)

Identification and characterization of CONSTANS-like genes from Curcuma alismatifolia - Yuan-Yuan Li; Xiao-Huang Chen; Hui-Wen Yu; Qi-Lin Tian; Luan-Mei Lu (Horticulture, Environment, and Biotechnology, 2021)

Effects of plant growth regulators and polyamines on bract longevity in Bougainvillea buttiana - Kuan-Hung Lin; Jui-Mei Li; Chun-Wei Wu; Yu-Sen Chang (Horticulture, Environment, and Biotechnology, 2021)

Microbiological profiles and antimicrobial resistance patterns of pediatric bloodstream pathogens in China, 2016–2018 - Yue Qiu; Junwen Yang; Yiping Chen; Jinhong Yang; Qingxiong Zhu; Chunhui Zhu; Shuangjie Li; Jing Liu; Chaomin Wan; Yu Zhu; Minxia Chen; Yi Xu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Adaptive Evolution of Chalcone Isomerase Superfamily in Fagaceae - Li-Mei Lin; Hong-Yu Guo; Xin Song; Duo-Duo Zhang; Yue-Hong Long; Zhao-Bin Xing (Biochemical Genetics, 2021)

New secondary metabolite with cytotoxicity from spawning soft coral Asterospicularia laurae in Taiwan - Jui-Hsin Su; Chih-I Liu; Mei-Chin Lu; Chi-I Chang; Min-Ying Hsieh; Yu-Chi Lin; Chang-Feng Dai; Ya-Han Zhang; Zheng-Yu Lin; Yun-Sheng Lin (Natural Product Research, 2021)

Interest-activity symptom severity predicts response to ketamine infusion in treatment-resistant depression - Mu-Hong Chen; Wei-Chen Lin; Hui-Ju Wu; Ya-Mei Bai; Cheng-Ta Li; Shih-Jen Tsai; Chen-Jee Hong; Pei-Chi Tu; Tung-Ping Su (Psychopharmacology, 2021)

Clinacanthus nutans Mitigates Neuronal Death and Reduces Ischemic Brain Injury: Role of NF-κB-driven IL-1β Transcription - Mei-Han Kao; Jui-Sheng Wu; Wai-Mui Cheung; Jin-Jer Chen; Grace Y. Sun; Wei-Yi Ong; Deron R. Herr; Teng-Nan Lin (NeuroMolecular Medicine, 2021)

Upregulation of long noncoding RNA XIST has anticancer effects on ovarian cancer through sponging miR-106a - Ting Guo; Donglan Yuan; Wei Zhang; Dandan Zhu; Aifang Xiao; Guangyao Mao; Wenjuan Jiang; Mei Lin; Jun Wang (Human Cell, 2021)

Identification of Aspergillus tubingensis causing pomegranate fruit rot in China - Mei Jun Guo; Qiu Tong Wang; Yuan Hui Cheng; Cheng Lin Hou (Australasian Plant Pathology, 2021)

Lentibacillus saliphilus. sp. nov., a moderately halophilic bacterium isolated from a saltern in Korea - Yun Wang; Gang-Qiang Jiang; Hong-Ping Lin; Peng Sun; Hong-Yan Zhang; Dong-Mei Lu; Li-Yun Wang; Chang-Jin Kim; Shu-Kun Tang (Archives of Microbiology, 2021)

First Detection and Molecular Identification of Entamoeba in Yaks from China - Mei Ren; Fan Yang; Jing-min Gou; Pin-xue Wang; Min Zou; Xiao-hong Zhong; Qing Lin (Acta Parasitologica, 2021)

Report of epibenthic macrofauna found from Haima cold seeps and adjacent deep-sea habitats, South China Sea - Dong Dong; Xinzheng Li; Mei Yang; Lin Gong; Yang Li; Jixing Sui; Zhibin Gan; Qi Kou; Ning Xiao; Junlong Zhang (Marine Life Science & Technology, 2021)
This work reports on a preliminary taxonomic study of epibenthic macroinvertebrates collected or observed by underwater video at the Haima cold seeps and in adjacent deep-sea habitats, including a mud volcano field and Ganquan Plateau, during an expedition in the South China Sea by the Chinese-manned submersible Shenhai Yongshi in May 2018. A total of 41 species belonging to 6 phyla were identified, among which 34 species were collected from the Haima cold seeps. Mollusks and crustaceans that are specialized in reducing habitats were predominant in biotopes of the Haima cold seeps, whereas sponges and cold-water corals and their commensals were prominent in communities of the mud volcano field and the slopes of Ganquan Plateau. The distribution and faunal composition of each taxonomic group are discussed.

Effects of high levels of nitrogen and phosphorus on perennial ryegrass (Lolium perenne L.) and its potential in bioremediation of highly eutrophic water - Hai-Shun Xu; Lin Zhu; Yi Mei (Environmental Science and Pollution Research, 2021)

The substrate‐dependent regulatory effects of the AfeI /R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles - Xue‐Yan Gao; Chang‐Ai Fu; Likai Hao; Xiu‐Feng Gu; Rui Wang; Jian‐Qiang Lin; Xiang‐Mei Liu; Xin Pang; Cheng‐Jia Zhang; Jian‐Qun Lin; Lin‐Xu Chen (Environmental Microbiology, 2021)
Summary A LuxI/R‐like quorum sensing (QS) system (AfeI/R) has been reported in the acidophilic and chemoautotrophic Acidithiobacillus spp. However, the function of AfeI/R remains unclear because of the difficulties in the genetic manipulation of these bacteria. Here, we constructed different afeI mutants of the sulfur‐ and iron‐oxidizer A . ferrooxidans , identified the N‐acyl homoserine lactones (acyl‐HSLs) synthesized by AfeI, and determined the regulatory effects of AfeI/R on genes expression, extracellular polymeric substance synthesis, energy metabolism, cell growth and population density of A . ferrooxidans in different energy substrates. Acyl‐HSLs‐mediated distinct regulation strategies were employed to influence bacterial metabolism and cell growth of A . ferrooxidans cultivated in either sulfur or ferrous iron. Based on these findings, an energy‐substrate‐dependent regulation mode of AfeI/R in A . ferrooxidans was illuminated that AfeI/R could produce different types of acyl‐HSLs and employ specific acyl‐HSLs to regulate specific genes in response to different energy substrates. The discovery of the AfeI/R‐mediated substrate‐dependent regulatory mode expands our knowledge on the function of QS system in the chemoautotrophic sulfur‐ and ferrous iron‐oxidizing bacteria, and provides new insights in understanding energy metabolism modulation, population control, bacteria‐driven bioleaching process, and the coevolution between the acidophiles and their acidic habitats.

Sesquiterpenoids and meroterpenoids from a mangrove derived fungus Diaporthe sp. SCSIO 41011 - Xiao-Wei Luo; Chun-Mei Chen; Kun-Long Li; Xiu-Ping Lin; Cheng-Hai Gao; Xue-Feng Zhou; Yong-Hong Liu (Natural Product Research, 2021)

Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications - Wei-Yi Ong; Mei-Lin Go; De-Yun Wang; Irwin Kee-Mun Cheah; Barry Halliwell (Molecular Neurobiology, 2021)
The SARS-CoV-2 virus that is the cause of coronavirus disease 2019 (COVID-19) affects not only peripheral organs such as the lungs and blood vessels, but also the central nervous system (CNS)—as seen by effects on smell, taste, seizures, stroke, neuropathological findings and possibly, loss of control of respiration resulting in silent hypoxemia. COVID-19 induces an inflammatory response and, in severe cases, a cytokine storm that can damage the CNS. Antimalarials have unique properties that distinguish them from other anti-inflammatory drugs. (A) They are very lipophilic, which enhances their ability to cross the blood-brain barrier (BBB). Hence, they have the potential to act not only in the periphery but also in the CNS, and could be a useful addition to our limited armamentarium against the SARS-CoV-2 virus. (B) They are non-selective inhibitors of phospholipase A 2 isoforms, including cytosolic phospholipase A 2 (cPLA 2 ). The latter is not only activated by cytokines but itself generates arachidonic acid, which is metabolized by cyclooxygenase (COX) to pro-inflammatory eicosanoids. Free radicals are produced in this process, which can lead to oxidative damage to the CNS. There are at least 4 ways that antimalarials could be useful in combating COVID-19. (1) They inhibit PLA 2. (2) They are basic molecules capable of affecting the pH of lysosomes and inhibiting the activity of lysosomal enzymes. (3) They may affect the expression and Fe 2+ /H + symporter activity of iron transporters such as divalent metal transporter 1 (DMT1), hence reducing iron accumulation in tissues and iron-catalysed free radical formation. (4) They could affect viral replication. The latter may be related to their effect on inhibition of PLA 2 isoforms. Inhibition of cPLA 2 impairs an early step of coronavirus replication in cell culture. In addition, a secretory PLA 2 (sPLA 2 ) isoform, PLA2G2D, has been shown to be essential for the lethality of SARS-CoV in mice. It is important to take note of what ongoing clinical trials on chloroquine and hydroxychloroquine can eventually tell us about the use of antimalarials and other anti-inflammatory agents, not only for the treatment of COVID-19, but also for neurovascular disorders such as stroke and vascular dementia.

A transport environmental Kuznets curve analysis for Malaysia: exploring the role of corruption - You-How Go; Lin-Sea Lau; Feng-Mei Liew; Abdelhak Senadjki (Environmental Science and Pollution Research, 2021)

Low ambient temperature increases hospital re-admissions for systemic lupus erythematosus in humid subtropical region: a time series study - Qian Wu; Zhiwei Xu; Yi-Lin Dan; Peng Wang; Yan-Mei Mao; Chan-Na Zhao; Yan-Feng Zou; Dong-Qing Ye; Wenbiao Hu; Hai-Feng Pan (Environmental Science and Pollution Research, 2021)

Long non-coding RNA LINC00460 promotes proliferation and inhibits apoptosis of cervical cancer cells by targeting microRNA-503-5p - Lin Lin; Bing Xin; Tao Jiang; Xin-lu Wang; Hua Yang; Tie-mei Shi (Molecular and Cellular Biochemistry, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Using sowing date management to promote micronutrient quality and alleviate cadmium accumulation in rice grains - Lin-lin Shi; Ming-xing Shen; Hong-jun Wu; Chang-ying Lu; Li-juan Mei; Xin-lian Zhu; Hai-hou Wang; Yun-Sheng Song (Cereal Research Communications, 2020)

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

Comparative performance assessment of landslide susceptibility models with presence-only, presence-absence, and pseudo-absence data - Dong-mei Zhao; Yuan-mei Jiao; Jin-liang Wang; Yin-ping Ding; Zhi-lin Liu; Cheng-jing Liu; Ying-mei Qiu; Juan Zhang; Qiu-e Xu; Chang-run Wu (Journal of Mountain Science, 2020)

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

Whether the carbon emission from green roofs can be effectively mitigated by recycling waste building material as green roof substrate during five-year operation? - Liangqian Fan; Jingting Wang; Xiaoling Liu; Hongbing Luo; Ke Zhang; Xiaoying Fu; Mei Li; Xiaoting Li; Bing Jiang; Jia Chen; Shuzhi Fu; You Mo; et al. (Environmental Science and Pollution Research, 2020)

Two new compounds from the heartwood of Dalbergia melanoxylon - Shuai Lin; Rong-Hua Liu; Guang-Qiang Ma; Dan-Yi Mei; Feng Shao; Lan-Ying Chen (Natural Product Research, 2020)

LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer’s disease - Chia-Hao Fan; Chia-Wei Lin; Hei-Jen Huang; Guey-Jen Lee-Chen; Ying-Chieh Sun; Wenwei Lin; Chiung-Mei Chen; Kuo-Hsuan Chang; Ming-Tsan Su; Hsiu Mei Hsieh-Li (Psychopharmacology, 2020)

Preparation and characterization of dissolving hyaluronic acid composite microneedles loaded micelles for delivery of curcumin - Ziting Cheng; Hua Lin; Zhen Wang; Xiaoyu Yang; Mei Zhang; Xuechun Liu; Bingjie Wang; Zhenfeng Wu; Daquan Chen (Drug Delivery and Translational Research, 2020)

(–)-β-Homoarginine anhydride, a new antioxidant and tyrosinase inhibitor, and further active components from Trichosanthes truncata - I-Ting Weng; Yen-An Lin; Guan-Yu Chen; Hsiu-Mei Chiang; Yi-Jung Liu; Chao-Jung Chen; Yu-Hsuan Lan; Chia-Lin Lee (Natural Product Research, 2020)

Identification and validation of stable quantitative trait loci for grain filling rate in common wheat (Triticum aestivum L.) - Yu Lin; Xiaojun Jiang; Yang Tao; Xilan Yang; Zhiqiang Wang; Fangkun Wu; Shihang Liu; Caixia Li; Mei Deng; Jian Ma; Guangdeng Chen; Yuming Wei; et al. (Theoretical and Applied Genetics, 2020)

Seasonal microclimate effect of Linpan settlements on the surrounding area in Chengdu Plain - Hua Zong; Wei Xiong; Mei-lin Liu; Qian Wang; Lian Zhang (Theoretical and Applied Climatology, 2020)

Neuroimaging Spectrum at Pre-, Early, and Late Symptomatic Stages of SCA17 Mice - Chiao-Chi Chen; Nai-Wei Yao; Chia-Wei Lin; Wei-Shuo Su; Chin-Tien Wu; Chen Chang; Hsiu Mei Hsieh-Li (The Cerebellum, 2020)

Mixture of Pb, Zn and Cu on root permeability and radial oxygen loss in the mangrove Bruguiera gymnorrhiza - Hao Cheng; You-Shao Wang; Chang-Da Li; Zhi-Hong Ye; Shafi Muhammad; Mei-Lin Wu; Fun-Lin Sun (Ecotoxicology, 2020)

Dynamics of radial oxygen loss in mangroves subjected to waterlogging - Hao Cheng; Mei-Lin Wu; Chang-Da Li; Fu-Lin Sun; Cui-Ci Sun; You-Shao Wang (Ecotoxicology, 2020)

Distribution patterns and source identification for heavy metals in Mirs Bay of Hong Kong in China - Mei-Lin Wu; Hao Cheng; Hui Zhao; Fu-Lin Sun; Yu-Tu Wang; Jian-Ping Yin; Jiao Fei; Cui-Ci Sun; You-Shao Wang (Ecotoxicology, 2020)

Phytoplankton community, structure and succession delineated by partial least square regression in Daya Bay, South China Sea - Mei-Lin Wu; Yu-Tu Wang; Hao Cheng; Fu-lin Sun; Jiao Fei; Cui-Ci Sun; Jian-Ping Yin; Hui Zhao; You-Shao Wang (Ecotoxicology, 2020)

Probabilistic stability analysis of earth dam slope under transient seepage using multivariate adaptive regression splines - Lin Wang; Chongzhi Wu; Xin Gu; Hanlong Liu; Guoxiong Mei; Wengang Zhang (Bulletin of Engineering Geology and the Environment, 2020)

Spatial Pattern of Female Non-agricultural Employment and Its Driving Forces in Guangdong Province, China: A Perspective of Individual and Family-level - Zhanhui Fu; Lin Mei; Yanjun Liu; Junfeng Tian; Rumin Zheng; Jing Tian (Chinese Geographical Science, 2020)

Correction to: Potato Cultivar Susceptibility to Pythium Leak as Influenced by Harvest and Early Storage Temperatures - Andrew K Hollingshead; Nora L. Olsen; Mike Thornton; Jeff S. Miller; Amy Hui-Mei Lin (American Journal of Potato Research, 2020)

Potato Cultivar Susceptibility to Pythium Leak as Influenced by Harvest and Early Storage Temperatures - Andrew K Hollingshead; Nora L. Olsen; Mike Thornton; Jeff S. Miller; Amy Hui-Mei Lin (American Journal of Potato Research, 2020)

Targeting Inflammation, PHA-767491 Shows a Broad Spectrum in Protein Aggregation Diseases - Yu-Han Chung; Chia-Wei Lin; Hsin-Yu Huang; Shu-Ling Chen; Hei-Jen Huang; Ying-Chieh Sun; Guan-Chiun Lee; Guey-Jen Lee-Chen; Ya-Ching Chang; Hsiu Mei Hsieh-Li (Journal of Molecular Neuroscience, 2020)

The chemical constituents from the active fractions of Eleutherine bulbosa with their antimicrobial activity - Hai Jiang; Wen-Jing Man; A-Jiao Hou; Lin Yang; Xu-Dong Xing; Mei-Ling Yan; Xin-Yue Guo; Liu Yang (Natural Product Research, 2020)

Long interpregnancy interval and adverse perinatal outcomes: A retrospective cohort study - Jing Lin; Han Liu; Dan-Dan Wu; Hong-Tao Hu; Hui-Hui Wang; Cheng-Liang Zhou; Xin-Mei Liu; Xiao-Jun Chen; Jian-Zhong Sheng; He-Feng Huang (Science China Life Sciences, 2020)

Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway - Chung-I Yu; Cheng-I Cheng; Ya-Fei Kang; Po-Chih Chang; In-Pin Lin; Yu-His Kuo; An-Jie Jhou; Mei-Ying Lin; Chung-Yi Chen; Chien-Hsing Lee (Neurotoxicity Research, 2020)

Protective effect of apigenin on d-galactosamine/LPS-induced hepatocellular injury by increment of Nrf-2 nucleus translocation - Rui-Jun Zhou; Ying Zhao; Ke Fan; Mei-Lin Xie (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

3D-QSAR, HQSAR, molecular docking, and new compound design study of 1,3,6-trisubstituted 1,4-diazepan-7-ones as human KLK7 inhibitors - Le Fu; Yi Chen; Chun-mei Xu; Tao Wu; Hong-mei Guo; Zhi-hua Lin; Rui Wang; Mao Shu (Medicinal Chemistry Research, 2020)

Automatic Striatal ROI Delineation for Semi-quantitative Analysis of 99mTc-TRODAT-1 Brain SPECT Imaging - Bang-Hung Yang; Kang-Ping Lin; Mei-Fen Chen; Jui-Hung Weng; Pan-Fu Kao; Wen-Chen Lin; Ren-Shyan Liu (Journal of Medical and Biological Engineering, 2020)

Mechanism study on co-processing of water-based drilling cuttings and phosphogypsum in non-autoclaved aerated concrete - Chao-qiang Wang; Xu-dong Mei; Chun Zhang; Dong-sheng Liu; Feng-lin Xu (Environmental Science and Pollution Research, 2020)

Combined effect of polymorphisms of MTHFR and MTR and arsenic methylation capacity on developmental delay in preschool children in Taiwan - Yu-Mei Hsueh; Ying-Chin Lin; Chi-Jung Chung; Ya-Li Huang; Ru-Lan Hsieh; Pai-Tsang Huang; Mei-Yi Wu; Horng-Sheng Shiue; Ssu-Ning Chien; Chih-Ying Lee; Ming-I. Lin; Shu-Chi Mu; et al. (Archives of Toxicology, 2020)

Detection of serum IgM and IgG for COVID-19 diagnosis - Ling Zhong; Junlan Chuan; Bo Gong; Ping Shuai; Yu Zhou; Yi Zhang; Zhilin Jiang; Dingding Zhang; Xiaoqi Liu; Shi Ma; Yi Huang; He Lin; et al. (Science China Life Sciences, 2020)

Acceleration of thaw slump during 1997–2017 in the Qilian Mountains of the northern Qinghai-Tibetan plateau - Cuicui Mu; Jianguo Shang; Tingjun Zhang; Chengyan Fan; Shufa Wang; Xiaoqing Peng; Wen Zhong; Feng Zhang; Mei Mu; Lin Jia (Landslides, 2020)

Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs. 3 doses in young women - Yue-Mei Hu; Meng Guo; Chang-Gui Li; Kai Chu; Wen-Gang He; Jing Zhang; Jian-Xiang Gu; Juan Li; Hui Zhao; Xiang-Hong Wu; BiZhen Lin; Zhi-Jie Lin; et al. (Science China Life Sciences, 2020)

Endometrial autophagy is essential for embryo implantation during early pregnancy - Yan Su; Juan-Juan Zhang; Jun-Lin He; Xue-Qing Liu; Xue-Mei Chen; Yu-Bin Ding; Chao Tong; Chuan Peng; Yan-Qing Geng; Ying-Xiong Wang; Ru-Fei Gao (Journal of Molecular Medicine, 2020)

Viral metagenomics reveals sapoviruses of different genogroups in stool samples from children with acute gastroenteritis in Jiangsu, China - Wang Li; Surong Dong; Juan Xu; Xiaobin Zhou; Junling Han; Zhaqing Xie; Qin Gong; Hailin Peng; Chenglin Zhou; Mei Lin (Archives of Virology, 2020)
Sapoviruses (SAVs), including several genogroups (GI to GV), are one of the causes of acute gastroenteritis (AGE). In this study, viral metagenomics revealed the presence of sapoviruses of different genogroups in stool from children with AGE. Eight different complete SAV genomes were determined, of which five belonged to GI and the other three belonged to GII, GIV and GV, respectively. Although they were highly similar to published sequences, the GIV and GV were the first complete genome sequences of these SAVs found in China. In a prevalence investigation, 19% of subjects with AGE were positive for SAVs, while none of the control group was positive.

Population Structure of the World Vegetable Center Mungbean Mini Core Collection and Genome-Wide Association Mapping of Loci Associated with Variation of Seed Coat Luster - Caleb Manamik Breria; Ching Hsiang Hsieh; Jo-Yi Yen; Ramakrishnan Nair; Chen-Yu Lin; Shu-Mei Huang; Thomas J. Noble; Roland Schafleitner (Tropical Plant Biology, 2020)

Endothelial Notch activation promotes neutrophil transmigration via downregulating endomucin to aggravate hepatic ischemia/reperfusion injury - Peiran Zhang; Kangyi Yue; Xinli Liu; Xianchun Yan; Ziyan Yang; Juanli Duan; Congcong Xia; Xinyuan Xu; Mei Zhang; Liang Liang; Lin Wang; Hua Han (Science China Life Sciences, 2020)

Scorpion Venom Heat-Resistant Peptide is Neuroprotective against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway - Xu-Gang Wang; Dan-Dan Zhu; Na Li; Yue-Lin Huang; Ying-Zi Wang; Ting Zhang; Chen-Mei Wang; Bin Wang; Yan Peng; Bi-Ying Ge; Shao Li; Jie Zhao (Neuroscience Bulletin, 2020)

Twist1 Plays an Anti-apoptotic Role in Mutant Huntingtin Expression Striatal Progenitor Cells - Wei-Ping Jen; Hui-Mei Chen; Yow-Sien Lin; Yijuang Chern; Yi-Ching Lee (Molecular Neurobiology, 2020)

Whole-genome mining and in silico analysis of FAD gene family in Brassica juncea - Yufei Xue; Chengyan Chai; Baojun Chen; Xiaofeng Shi; Bitao Wang; Fanrong Mei; Manlin Jiang; Xueli Liao; Xia Yang; Chenglong Yuan; Lin Zhang; Yourong Chai (Journal of Plant Biochemistry and Biotechnology, 2020)

Plasma biomarkers and plaque strain predict long-term cardiovascular events in patients with acute coronary syndrome - Mingjun Xu; Xiaobo Hu; Lin Wang; Wei Zhang; Lindi Wu; Jifu Li; Yuguo Chen; Pengfei Zhang; Haijun Su; Yaling Han; Cheng Zhang; Mei Zhang; et al. (Science China Life Sciences, 2020)

Comparative Study of Regulations of Devices for Aesthetic Purposes: US, European Union, China, and Taiwan - Mei-Fen Chen; Cheng-Lun Tsai; Yung-Hsin Chen; Cheng-Ning Wu; Ching Chou; Chia-Hung Chien; Pei-Weng Tu; Tsair Kao; Kang-Ping Lin (Journal of Medical and Biological Engineering, 2020)

High dietary lipid level alters the growth, hepatic metabolism enzyme, and anti-oxidative capacity in juvenile largemouth bass Micropterus salmoides - Yue-Lang Zhou; Jia-Ling Guo; Ren-Jun Tang; Hui-Jia Ma; Yong-Jun Chen; Shi-Mei Lin (Fish Physiology and Biochemistry, 2020)

Land use scenario simulation of mountainous districts based on Dinamica EGO model - Lin-lin Cheng; Mei Liu; Jia-qi Zhan (Journal of Mountain Science, 2020)

Synthesis and biological evaluation of C-13, C-14 modified taxane analogues from 1-deoxybaccatin VI - Ping Tang; Hai-Xia Lin; Tian-Hai Yuan; Yong-Mei Cui (Natural Product Research, 2019)

Correction to: Soluble Epoxide Hydrolase Inhibition Attenuates Excitotoxicity Involving 14,15-Epoxyeicosatrienoic Acid–Mediated Astrocytic Survival and Plasticity to Preserve Glutamate Homeostasis - Yi-Min Kuo; Pei-Chien Hsu; Chia-Chi Hung; Ya-Yu Hu; Yu-Jie Huang; Yu-Ling Gan; Chun-Hua Lin; Feng-Shiun Shie; Wen-Kuei Chang; Lung-Sen Kao; Mei-Yung Tsou; Yi-Hsuan Lee (Molecular Neurobiology, 2019)

Soluble Epoxide Hydrolase Inhibition Attenuates Excitotoxicity Involving 14,15-Epoxyeicosatrienoic Acid–Mediated Astrocytic Survival and Plasticity to Preserve Glutamate Homeostasis - Yi-Min Kuo; Pei-Chien Hsu; Chia-Chi Hung; Ya-Yu Hu; Yu-Jie Huang; Yu-Ling Gan; Chun-Hua Lin; Feng-Shiun Shie; Wen-Kuei Chang; Lung-Sen Kao; Mei-Yung Tsou; Yi-Hsuan Lee (Molecular Neurobiology, 2019)

Long-term variations of atmospheric angular momentum and torque - He Gong; Mei Huang; Lin Zhu; Yaping Shao (Meteorology and Atmospheric Physics, 2019)

Age- and Nicotine-Associated Gene Expression Changes in the Hippocampus of APP/PS1 Mice - Jie Yang; Yan Long; De-Mei Xu; Bing-Lin Zhu; Xiao-Juan Deng; Zhen Yan; Fei Sun; Guo-Jun Chen (Journal of Molecular Neuroscience, 2019)

NRG1–ErbB4 signaling promotes functional recovery in a murine model of traumatic brain injury via regulation of GABA release - Weike Deng; Fei Luo; Bao-ming Li; Lin Mei (Experimental Brain Research, 2019)

Forecasts of MJO Events during DYNAMO with a Coupled Atmosphere-Ocean Model: Sensitivity to Cumulus Parameterization Scheme - Mei-Yu Chang; Tim Li; Pay-Liam Lin; Ting-Huai Chang (Journal of Meteorological Research, 2019)

Using 1-propanol to significantly enhance the production of valuable odd-chain fatty acids by Rhodococcus opacus PD630 - Lin-Shang Zhang; Pei Xu; Mei-Yun Chu; Min-Hua Zong; Ji-Guo Yang; Wen-Yong Lou (World Journal of Microbiology and Biotechnology, 2019)

Correction to: Fungi participate in driving home-field advantage of litter decomposition in a subtropical forest - Dunmei Lin; Mei Pang; Nicolas Fanin; Hongjuan Wang; Shenhua Qian; Liang Zhao; Yongchuan Yang; Xiangcheng Mi; Keping Ma (Plant and Soil, 2019)

A new indole-type alkaloid from the roots of Clematis florida var. plena - Kai-Hui Sun; Xin-Hua Ma; Xian-Ming Zeng; Zhong-Yue Lin; Yu-Mei Cai; Hai-Tao Zhang; Xiao-Yan Lin; Shi-Biao Feng; Tian-Hua Zhong; Yong-Hong Zhang (Natural Product Research, 2019)

Evaluation of Coherence Between ECG and PPG Derived Parameters on Heart Rate Variability and Respiration in Healthy Volunteers With/Without Controlled Breathing - Hao-Yu Jan; Mei-Fen Chen; Tieh-Cheng Fu; Wen-Chen Lin; Cheng-Lun Tsai; Kang-Ping Lin (Journal of Medical and Biological Engineering, 2019)

Linseed oil can decrease liver fat deposition and improve antioxidant ability of juvenile largemouth bass, Micropterus salmoides - Chao-Ming Shi; Hang Zhao; Xv-Liang Zhai; Yong-Jun Chen; Shi-Mei Lin (Fish Physiology and Biochemistry, 2019)

Occurrence of Bryde's whales, Balaenoptera edeni , in the northern Beibu Gulf, China - Mo Chen; Shiang‐Lin Huang; Haiping Wu; Zhigang Mei; Yiwen Chen; Jingsong Zheng; Wen Cheng; Keshun Deng; Chengteng Yang; Mao Chen; Chun‐Chieh Wang; Derun Lin; et al. (Marine Mammal Science, 2019)

Predominant effects of litter chemistry on lignin degradation in the early stage of leaf litter decomposition - Mei He; Rudong Zhao; Qiuxiang Tian; Lin Huang; Xinggang Wang; Feng Liu (Plant and Soil, 2019)

Effects of drought–re-watering–drought on the photosynthesis physiology and secondary metabolite production of Bupleurum chinense DC. - Linlin Yang; Yu Zhao; Qi Zhang; Lin Cheng; Mei Han; Yueying Ren; Limin Yang (Plant Cell Reports, 2019)

Usage patterns and comfort of gardens: a seasonal survey of internal garden microclimate in the aged care homes of Chengdu City - Hua Zong; Yin Liu; Qian Wang; Mei-lin Liu; Han Chen (International Journal of Biometeorology, 2019)

The complete chloroplast genome of Taiwania cryptomerioides (Cupressales: Cupressaceae), an endangered relict conifer species endemic to East Asia - Ling-Li Wang; Yong-Liang Shi; Qi-Lin Zhang; Yan-Ru Guo; Hong-Mei Teng (Conservation Genetics Resources, 2019)

Association of plasma folate, vitamin B12 levels, and arsenic methylation capacity with developmental delay in preschool children in Taiwan - Ying-Chin Lin; Chi-Jung Chung; Ya-Li Huang; Ru-Lan Hsieh; Pai-Tsang Huang; Mei-Yi Wu; Pui-Lam Ao; Horng-Sheng Shiue; Shiau-Rung Huang; Chien-Tien Su; Ming-I Lin; Shu-Chi Mu; et al. (Archives of Toxicology, 2019)

The Neuroprotective Effect of L-Stepholidine on Methamphetamine-Induced Memory Deficits in Mice - Mei Zhou; Xiaokang Gong; Qin Ru; Qi Xiong; Lin Chen; Yuanren Si; Huaqiao Xiao; Chaoying Li (Neurotoxicity Research, 2019)

Half-dose ticagrelor versus high-dose clopidogrel in reducing platelet reactivity in acute coronary syndrome patients with high on-clopidogrel platelet reactivity (divide study) - Guang Zhong Liu; Song Zhang; Dang Hui Sun; Jing Shi; Wan Lan Bo; Wen Nan Wang; Chong Yang Zhang; Zhong Hua Wang; Wei Feng; Mei Jiao He; Yuan Yuan Liu; Shuang Li; et al. (European Journal of Clinical Pharmacology, 2019)

Progressive multifocal leukoencephalopathy in a renal transplant patient - Tsu-Chen Lin; Mei-Yi Wu; Hui-Tzung Luh; Shiou-Fu Lin; Chien-Min Lin; Ying-Chi Tseng; Yung-Ching Liu; Mai-Szu Wu (Journal of NeuroVirology, 2019)

Design, synthesis and biological evaluation of novel indone derivatives as selective ERβ modulators - Xi-Xi Liu; Mei-Lin Tang; Chen Zhong; Yun Tang; Jian-Ming Yu; Xun Sun (Medicinal Chemistry Research, 2019)

Diversity of endosymbiotic Symbiodiniaceae in giant clams at Dongsha Atoll, northern South China Sea - Sherlyn Sher Qing Lim; Danwei Huang; Keryea Soong; Mei Lin Neo (Symbiosis, 2019)

Lignans, flavonoids and coumarins from Viola philippica and their α-glucosidase and HCV protease inhibitory activities - Ya-Li Wang; Lin Zhang; Meng-Yan Li; Li-Wei Wang; Chao-Mei Ma (Natural Product Research, 2019)

Favus of Scrotum Due to Trichophyton rubrum in Immunocompetent Patients: A Clinical, Mycological and Ultrastructural Study - Ze-Hu Liu; Xiu-Jiao Xia; Yong Zhang; Yan Zhong; Bo Sang; Qiu-Ping Li; Mei Wang; Wen-Wen Lv; Hui-Lin Zhi; Xiang-Dong Wang; Cui-Ping Guan; Hong Shen (Mycopathologia, 2019)

Modeling Alzheimer’s Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation - Kuo-Hsuan Chang; Guey-Jen Lee-Chen; Ching-Chang Huang; Jia-Li Lin; Yi-Jing Chen; Pei-Chi Wei; Yen-Shi Lo; Chin-Fa Yao; Ming-Wei Kuo; Chiung-Mei Chen (Molecular Neurobiology, 2019)

Quantitative trait locus mapping for panicle exsertion length in common wheat using two related recombinant inbred line populations - Yang Tao; Xin Yi; Yu Lin; Zhiqiang Wang; Fangkun Wu; Xiaojun Jiang; Shihang Liu; Mei Deng; Jian Ma; Guangdeng Chen; Yuming Wei; Youliang Zheng; et al. (Euphytica, 2019)

Mercury–Organic Matter Interactions in Soils and Sediments: Angel or Devil? - Mei He; Lei Tian; Hans Fredrik Veiteberg Braaten; Qingru Wu; Jie Luo; Li-Mei Cai; Jiang-Hui Meng; Yan Lin (Bulletin of Environmental Contamination and Toxicology, 2019)

The effects of different pharmacological agent treatments on ROS accumulation and functional protein activities in wheat endosperm PCD - Ze Lin; Yuanhong Qi; Dongcheng Liu; Fangfang Mao; Xiangyi Deng; Jiwei Li; Fangzhu Mei; Zhuqing Zhou (Acta Physiologiae Plantarum, 2019)

Rainfall difference between the deposition fan and source area of Touzhai Landslide in Yunnan, China - Kun Wang; Zhe Ren; Xuefeng Mei; Lin Tian; Kui Yang; Zhenhua Zhou; Jianjie Luo; Zemin Xu (Bulletin of Engineering Geology and the Environment, 2019)

Drastic decline in giant clams (Bivalvia: Tridacninae) around Mauritius Island, Western Indian Ocean: implications for conservation and management - Sundy Ramah; Nawsheen Taleb-Hossenkhan; Peter A. Todd; Mei Lin Neo; Ranjeet Bhagooli (Marine Biodiversity, 2019)

Posttraumatic Stress Disorder Augments Plasma Triglycerides in TT Homozygotes of rs495225 at Growth Hormone Secretagogue Receptor Gene - Mi Su; Yan Jun Si; Qi Wei Guo; Mei Yang; Xu Chen; Jia Lin; Ding Zhi Fang (Biochemical Genetics, 2019)

Large-scale analysis of small RNAs derived from traditional Chinese herbs in human tissues - Fengming Huang; Jianchao Du; Zhu Liang; Zhichao Xu; Jiantao Xu; Yan Zhao; Yexuan Lin; Song Mei; Quan He; Jindong Zhu; Qiang Liu; Yanxu Zhang; et al. (Science China Life Sciences, 2019)

Expression of the intrarenal angiotensin receptor and the role of renin-angiotensin system inhibitors in IgA nephropathy - Zheng Zhang; Shi-min Jiang; Ye-ping Ma; Pei-lin Dai; Yi-ning Wang; Gu-ming Zou; Hong-mei Gao; Yue Yang; Wen-ge Li (Molecular and Cellular Biochemistry, 2019)

Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides - Qing-Yan Tang; Geng Chen; Wan-Ling Song; Wei Fan; Kun-Hua Wei; Si-Mei He; Guang-Hui Zhang; Jun-Rong Tang; Ying Li; Yuan Lin; Sheng-Chao Yang (Planta, 2019)

A new benzofuran from the heartwood of Dalbergia latifolia - Rong-Hua Liu; Dan-Yi Mei; Shuai Lin; Ding-Qing Wang; Feng Shao; Lan-Ying Chen; Shan-Liang Guo (Natural Product Research, 2019)

Fungi participate in driving home-field advantage of litter decomposition in a subtropical forest - Dunmei Lin; Mei Pang; Nicolas Fanin; Hongjuan Wang; Shenhua Qian; Liang Zhao; Yongchuan Yang; Xiangcheng Mi; Keping Ma (Plant and Soil, 2019)

Atorvastatin ameliorates the contractile dysfunction of the aorta induced by organ culture - Feng Zhou; Fang Rao; You-Qing Deng; Hui Yang; Su-Juan Kuang; Fei-Long Wu; Shu-Lin Wu; Yu-Mei Xue; Xiao-Mu Wu; Chun-Yu Deng (Naunyn-Schmiedeberg's Archives of Pharmacology, 2019)

Postprandial change in glucose metabolism at the molecular level in the adipose tissue of omnivorous GIFT Oreochromis niloticus - Jing-Yun Feng; Qin-Qin Liu; Hang-Zhong Xu; Rui-Hong Chen; Li Luo; Shi-Mei Lin; Yong-Jun Chen; De-Shou Wang (Fisheries Science, 2019)

Transcriptome Reveals Differentially Expressed Genes in Saccharum spontaneum GX83-10 Leaf Under Drought Stress - Kai-Chao Wu; Li-Ping Wei; Cheng-Mei Huang; Yuan-Wen Wei; Hui-Qing Cao; Lin Xu; Hai-Bin Luo; Sheng-Li Jiang; Zhi-Nian Deng; Yang-Rui Li (Sugar Tech, 2018)

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease - Chia-Chia Lee; Ching-Pang Chang; Chun-Jung Lin; Hsing-Lin Lai; Yu-Han Kao; Sin-Jhong Cheng; Hui-Mei Chen; Yu-Ping Liao; Emilie Faivre; Luc Buée; David Blum; Jim-Min Fang; et al. (Molecular Neurobiology, 2018)

EGb761 improves the cognitive function of elderly db/db−/− diabetic mice by regulating the beclin-1 and NF-κB signaling pathways - Zhu-Fei Guan; Xiao-Ming Zhang; Ying-Hong Tao; Yu Zhang; Yan-Yan Huang; Gang Chen; Wei-Jun Tang; Gang Ji; Qi-Lin Guo; Ming Liu; Qian Zhang; Na-Na Wang; et al. (Metabolic Brain Disease, 2018)

Risk factors and drug resistance in early-onset neonatal group B streptococcal disease - Ying-wei Wang; Yao-qiang Du; Xiao-lin Miao; Guang-yong Ye; Yi-yun Wang; Ai-bo Xu; Yun-zhong Jing; Yu Tong; Kai Xu; Mei-qin Zheng; Dong Chen; Zhen Wang (Journal of Zhejiang University-SCIENCE B, 2018)

Species diversity and molecular phylogeny of non-geniculate coralline algae (Corallinophycidae, Rhodophyta) from Taoyuan algal reefs in northern Taiwan, including Crustaphytum gen. nov. and three new species - Li-Chia Liu; Showe-Mei Lin; Annalisa Caragnano; Claude Payri (Journal of Applied Phycology, 2018)

A genetic diversity assessment of Halymenia malaysiana (Halymeniaceae, Rhodophyta) from Malaysia and the Philippines based on COI-5P and rbcL sequences - Pui-Ling Tan; Phaik-Eem Lim; Showe-Mei Lin; Siew-Moi Phang; Stefano G.A. Draisma; Lawrence M. Liao (Journal of Applied Phycology, 2018)

DNA barcoding of traded shark fins, meat and mobulid gill plates in Singapore uncovers numerous threatened species - Benjamin J. Wainwright; Yin Cheong Aden Ip; Mei Lin Neo; Jia Jin Marc Chang; Chester Zhikai Gan; Naomi Clark-Shen; Danwei Huang; Madhu Rao (Conservation Genetics, 2018)

First observations of Tridacna noae (Röding, 1798) (Bivalvia: Heterodonta: Cardiidae) in Christmas Island (Indian Ocean) - Mei Lin Neo; Jeffrey K. Y. Low (Marine Biodiversity, 2018)

Analyzing Influencing Factors of Rural Poverty in Typical Poverty Areas of Hainan Province: A Case Study of Lingao County - Jinping Zhang; Feng Zuo; Yanmei Zhou; Mengxiao Zhai; Lin Mei; Yidi Fu; Yeqing Cheng (Chinese Geographical Science, 2018)

NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation - Yi-Mei J. Lin; I-Lun Hsin; H. Sunny Sun; Shankung Lin; Yen-Ling Lai; Hsuan-Ying Chen; Ting-Yu Chen; Ya-Ping Chen; Yi-Ting Shen; Hung-Ming Wu (Molecular Neurobiology, 2018)

A new C -glycosyl flavone and a new neolignan glycoside from Passiflora edulis Sims peel - Yue Hu; Lin Jiao; Min-Hong Jiang; Sheng Yin; Pan Dong; Zhi-Min Zhao; De-Po Yang; Pei-Tsai Ho; Dong-Mei Wang (Natural Product Research, 2018)

A Novel MYCN Variant Associated with Intellectual Disability Regulates Neuronal Development - Xiuya Yu; Liyuan Hu; Xu Liu; Guodong Zhan; Mei Mei; Huijun Wang; Xiaohua Zhang; Zilong Qiu; Wenhao Zhou; Lin Yang (Neuroscience Bulletin, 2018)

Cyproheptadine Regulates Pyramidal Neuron Excitability in Mouse Medial Prefrontal Cortex - Yan-Lin He; Kai Wang; Qian-Ru Zhao; Yan-Ai Mei (Neuroscience Bulletin, 2018)

Web-Based Experience Sharing Platform on Medical Device Incidents for Clinical Engineers in Hospitals - Mei-Fen Chen; Cheng-Lun Tsai; Yung-Hsin Chen; Yu-Wen Huang; Cheng-Ning Wu; Ching Chou; Chia-Hung Chien; Pei-Weng Tu; Tsair Kao; Kang-Ping Lin (Journal of Medical and Biological Engineering, 2018)

Characterization and adsorption capacity of potassium permanganate used to modify activated carbon filter media for indoor formaldehyde removal - Shih-Cheng Hu; Ying-Chen Chen; Xin-Zhi Lin; Angus Shiue; Po-Hua Huang; Yen-Che Chen; Shu-Mei Chang; Chao-Heng Tseng; Bin Zhou (Environmental Science and Pollution Research, 2018)

Combined ultrasound with Fenton treatment for the degradation of carcinogenic polycyclic aromatic hydrocarbons in textile dying sludge - Jian-Hao Zhang; Hai-Yuan Zou; Xun-An Ning; Mei-Qing Lin; Chang-Min Chen; Tai-Cheng An; Jian Sun (Environmental Geochemistry and Health, 2018)

Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer - Lin-Lin Cao; Hangqi Liu; Zhihong Yue; Lianhua Liu; Lin Pei; Junxu Gu; Hui Wang; Mei Jia (BioMetals, 2018)

Patterns and drivers of species diversity in the Indo‐Pacific red seaweed Portieria - Frederik Leliaert; Dioli Ann Payo; Carlos Frederico D. Gurgel; Tom Schils; Stefano G. A. Draisma; Gary W. Saunders; Mitsunobu Kamiya; Alison R. Sherwood; Showe‐Mei Lin; John M. Huisman; Line Le Gall; Robert J. Anderson; et al. (Journal of Biogeography, 2018)
Aim Biogeographical processes underlying Indo‐Pacific biodiversity patterns have been relatively well studied in marine shallow water invertebrates and fishes, but have been explored much less extensively in seaweeds, despite these organisms often displaying markedly different patterns. Using the marine red alga Portieria as a model, we aim to gain understanding of the evolutionary processes generating seaweed biogeographical patterns. Our results will be evaluated and compared with known patterns and processes in animals. Location Indo‐Pacific marine region. Methods Species diversity estimates were inferred using DNA ‐based species delimitation methods. Historical biogeographical patterns were inferred based on a six‐gene time‐calibrated phylogeny, distribution data of 802 specimens, and probabilistic modelling of geographical range evolution. The importance of geographical isolation for speciation was further evaluated by population genetic analyses at the intraspecific level. Results We delimited 92 candidate species, most with restricted distributions, suggesting low dispersal capacity. Highest species diversity was found in the Indo‐Malay Archipelago ( IMA ). Our phylogeny indicates that Portieria originated during the late Cretaceous in the area that is now the Central Indo‐Pacific. The biogeographical history of Portieria includes repeated dispersal events to peripheral regions, followed by long‐term persistence and diversification of lineages within those regions, and limited dispersal back to the IMA . Main conclusions Our results suggest that the long geological history of the IMA played an important role in shaping Portieria diversity. High species richness in the IMA resulted from a combination of speciation at small spatial scales, possibly as a result of increased regional habitat diversity from the Eocene onwards, and species accumulation via dispersal and/or island integration through tectonic movement. Our results are consistent with the biodiversity feedback model, in which biodiversity hotspots act as both “centres of origin” and “centres of accumulation,” and corroborate previous findings for invertebrates and fish that there is no single unifying model explaining the biological diversity within the IMA .

Activating adenosine A1 receptor accelerates PC12 cell injury via ADORA1/PKC/KATP pathway after intermittent hypoxia exposure - Hong-Fang Mei; Neha Poonit; Yi-Chun Zhang; Chu-Yuan Ye; Hui-Lin Cai; Chen-Yi Yu; Yong-Hai Zhou; Bei-bei Wu; Jun Cai; Xiao-Hong Cai (Molecular and Cellular Biochemistry, 2018)

Activation of histamine H4 receptor suppresses the proliferation and invasion of esophageal squamous cell carcinoma via both metabolism and non-metabolism signaling pathways - Gong-Hao He; Jia-Qi Ding; Xin Zhang; Wen-Mang Xu; Xiao-Qian Lin; Mei-Jin Huang; Ju Feng; Ping Wang; Wen-Ke Cai (Journal of Molecular Medicine, 2018)

Factors regulating carbon sinks in mangrove ecosystems - Shi‐Bo Li; Po‐Hung Chen; Jih‐Sheng Huang; Mei‐Li Hsueh; Li‐Yung Hsieh; Chen‐Lu Lee; Hsing‐Juh Lin (Global Change Biology, 2018)
Mangroves are recognized as one of the richest carbon storage systems. However, the factors regulating carbon sinks in mangrove ecosystems are still unclear, particularly in the subtropical mangroves. The biomass, production, litterfall, detrital export and decomposition of the dominant mangrove vegetation in subtropical ( Kandelia obovata ) and tropical ( Avicennia marina ) Taiwan were quantified from October 2011 to July 2014 to construct the carbon budgets. Despite the different tree species, a principal component analysis revealed the site or environmental conditions had a greater influence than the tree species on the carbon processes. For both species, the net production (NP) rates ranged from 10.86 to 27.64 Mg C ha −1 year −1 and were higher than the global average rate due to the high tree density. While most of the litterfall remained on the ground, a high percentage (72%–91%) of the ground litter decomposed within 1 year and fluxed out of the mangroves. However, human activities might cause a carbon flux into the mangroves and a lower NP rate. The rates of the organic carbon export and soil heterotrophic respiration were greater than the global mean values and those at other locations. Only a small percentage (3%–12%) of the NP was stored in the sediment. The carbon burial rates were much lower than the global average rate due to their faster decomposition, indicating that decomposition played a critical role in determining the burial rate in the sediment. The summation of the organic and inorganic carbon fluxes and soil heterotrophic respiration well exceeded the amount of litter decomposition, indicating an additional source of organic carbon that was unaccounted for by decomposition in the sediment. Sediment‐stable isotope analyses further suggest that the trapping of organic matter from upstream rivers or adjacent waters contributed more to the mangrove carbon sinks than the actual production of the mangrove trees.

Association Between Body Mass Index and Disease Severity in Chinese Spinocerebellar Ataxia Type 3 Patients - Jin-Shan Yang; Ping-Ping Chen; Min-Ting Lin; Mei-Zhen Qian; Hui-Xia Lin; Xiao-Ping Chen; Xian-Jin Shang; Dan-Ni Wang; Yu-Chao Chen; Bin Jiang; Yi-Jun Chen; Ning Wang; et al. (The Cerebellum, 2018)

Development and evaluation of a storm surge warning system in Taiwan - Mei-Ying Lin; Wen-Yih Sun; Ming-Da Chiou; Chih-Ying Chen; Hao-Yuan Cheng; Cheng-Hsin Chen (Ocean Dynamics, 2018)

Exploration of phenol tolerance mechanism through antioxidative responses of an evolved strain, Chlorella sp. L5 - Lin Zhou; Yizhong Yuan; Xuyang Li; Shouhua Mei; Juan Gao; Quanyu Zhao; Wei Wei; Yuhan Sun (Journal of Applied Phycology, 2018)

The response of zooplankton communities to the 2016 extreme hydrological cycle in floodplain lakes connected to the Yangtze River in China - Kun Zhang; Mei Xu; Qili Wu; Zhi Lin; Fangyuan Jiang; Huan Chen; Zhongze Zhou (Environmental Science and Pollution Research, 2018)

A New Approach of Rpf Addition to Explore Bacterial Consortium for Enhanced Phenol Degradation Under High Salinity Conditions - Ziqiao Li; Yunge Zhang; Yuyang Wang; Rongwu Mei; Yu Zhang; Muhammad Zaffar Hashmi; Hongjun Lin; Xiaomei Su (Current Microbiology, 2018)

Temporal and Spatial Variations of Microbial Carbon Utilization in Water Bodies from the Dajiuhu Peatland, Central China - Rui-Cheng Wang; Hong-Mei Wang; Xing Xiang; Yu Gao; Qing-Wei Song; Lin-Feng Gong (Journal of Earth Science, 2018)

Clinacanthus nutans Mitigates Neuronal Apoptosis and Ischemic Brain Damage Through Augmenting the C/EBPβ-Driven PPAR-γ Transcription - Jui-Sheng Wu; Mei-Han Kao; Hsin-Da Tsai; Wai-Mui Cheung; Jin-Jer Chen; Wei-Yi Ong; Grace Y. Sun; Teng-Nan Lin (Molecular Neurobiology, 2018)

Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes - Hsiao-Wen Huang; Yen-Hung Lin; Min-Hsuan Lin; Ya-Rong Huang; Chih-Hung Chou; Hsiao-Chin Hong; Mei-Ren Wang; Yu-Ting Tseng; Po-Chun Liao; Min-Chuan Chung; Yu-Jie Ma; Shou-Cheng Wu; et al. (JBIC Journal of Biological Inorganic Chemistry, 2018)

Recombinant rabies virus expressing interleukin-6 enhances the immune response in mouse brain - Jun Luo; Boyue Zhang; Yuting Wu; Qin Tian; Meijun Mo; Teng Long; Mingzhu Mei; Ruqi Fan; Ziyu Lyu; He Jiang; Fan Wu; Yingyi Lin; et al. (Archives of Virology, 2018)

A new antiviral pregnane from a gorgonian-derived Cladosporium sp. fungus - Mei-Lin Yu; Fei-Fei Guan; Fei Cao; Yan-Lai Jia; Chang-Yun Wang (Natural Product Research, 2018)

Study on the Clinical Features and Prognosis of Penicilliosis marneffei Without Human Immunodeficiency Virus Infection - Ying-ge Wang; Jin-mei Cheng; Hai-bo Ding; Xi Lin; Guo-hao Chen; Mei Zhou; Sheng-nan Ye (Mycopathologia, 2018)

Trade-offs between defence and competition in gregarious juvenile fluted giant clams (Tridacna squamosa L.) - Darren Z. H. Sim; Mei Lin Neo; Ambert C. F. Ang; Lynette S. M. Ying; Peter A. Todd (Marine Biology, 2018)

Identifying crack initiation stress threshold in brittle rocks using axial strain stiffness characteristics - Mei-ben Gao; Tian-bin Li; Lu-bo Meng; Chun-chi Ma; Hui-lin Xing (Journal of Mountain Science, 2018)

Impact of mixed anthropogenic and natural emissions on air quality and eco-environment—the major water-soluble components in aerosols from northwest to offshore isle - Yilun Jiang; Guoshun Zhuang; Qiongzhen Wang; Kan Huang; Congrui Deng; Guangyuan Yu; Chang Xu; Qingyan Fu; Yanfen Lin; Joshua S. Fu; Mei Li; Zhen Zhou (Air Quality, Atmosphere & Health, 2018)

Long-term study on seasonal changes in floristic composition and structure of marine macroalgal communities along the coast of Northern Taiwan, southern East China Sea - Showe-Mei Lin; Li-Chun Tseng; Put O. Ang; John Bolton; Li-Chia Liu (Marine Biology, 2018)

Phylogenetic analysis of IRIS L. from China on chloroplast TRNL-F sequences - Yu-Lin Jiang; Zhuo Huang; Jin-Qiu Liao; Hui-Xing Song; Xiao-Mei Luo; Su-Ping Gao; Ting Lei; Ming-Yan Jiang; Yin Jia; Qi-Bing Chen; Xiao-Fang Yu; Yong-Hong Zhou (Biologia, 2018)

Effect of UGT2B7 genotypes on plasma concentration of valproic acid: a meta-analysis - Ping Wang; Xiao-Qian Lin; Wen-Ke Cai; Gui-Li Xu; Meng-Di Zhou; Mei Yang; Gong-Hao He (European Journal of Clinical Pharmacology, 2018)

Trichogramma parasitoids can distinguish between fertilized and unfertilized host eggs - Wen-Mei Du; Jing Xu; Yang-Yang Hou; Ying Lin; Lian-Sheng Zang; Xiangbing Yang; Jun-Jie Zhang; Chang-Chun Ruan; Nicolas Desneux (Journal of Pest Science, 2018)

Halymenia johorensis sp. nov. (Halymeniaceae, Rhodophyta), a new foliose red algal species from Malaysia - Pui-Ling Tan; Phaik -Eem Lim; Showe-Mei Lin; Siew-Moi Phang (Journal of Applied Phycology, 2018)

Effect of dietary phospholipid levels on growth, lipid metabolism, and antioxidative status of juvenile hybrid snakehead (Channa argus×Channa maculata) - Shi-Mei Lin; Fa-Jian Li; Bundit Yuangsoi; Sompong Doolgindachbaporn (Fish Physiology and Biochemistry, 2018)

Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China - Zhi-Qi Zeng; De-Hui Chen; Wei-Ping Tan; Shu-Yan Qiu; Duo Xu; Huan-Xi Liang; Mei-Xin Chen; Xiao Li; Zheng-Shi Lin; Wen-Kuan Liu; Rong Zhou (European Journal of Clinical Microbiology & Infectious Diseases, 2018)