Variations of suspended sediment transport caused by changes in shoreline and bathymetry in the Zhujiang (Pearl) River Estuary in the wet season - Shicheng Lin; Jianwei Niu; Guangping Liu; Xing Wei; Shuqun Cai (Acta Oceanologica Sinica, 2022)

Countrywide inter‐epidemic region migration pattern suggests the role of southwestern population in wheat stripe rust epidemics in China - Muhammad Awais; Sajid Ali; Meng Ju; Wei Liu; Gensheng Zhang; Zedong Zhang; Zejian Li; Xinyao Ma; Lin Wang; Zhimin Du; Xiaxia Tian; Qingdong Zeng; et al. (Environmental Microbiology, 2022)
Understanding countrywide pathogen population structure and inter‐epidemic region spread is crucial for deciphering crop potential losses. Wheat stripe rust caused by Puccinia striiformis f. sp. tritici is a destructive disease that affects worldwide wheat production, widespread in China, representing largest epidemic region globally. This study aimed to understand the population structure and migration route of P . striiformis f. sp. tritici across China based on sampling from 15 provinces representing six epidemic zones, viz., over‐summering, over‐wintering, eastern, Yun‐Gui, Xinjiang and Tibet epidemic regions. High genotypic diversity was recorded in over‐summering, Tibet and over‐wintering epidemic regions. Epidemic regions partly explain population subdivision with variable divergence ( F ST = 0.005–0.344). Xinjiang and Tibet epidemic regions were independent epidemic zones with least sharing of genotypes. Among other epidemic zones, i.e. over‐summering, over‐wintering, eastern and Yun‐Gui epidemic zones, re‐sampling MLGs, clustering‐based structure, DAPC analyses, relative migration and low divergence ( F ST from 0.006 to 0.073) revealed frequent geneflow. Yun‐Gui epidemic regions, with a potential for both over‐summering and over‐wintering, could play an important role in causing epidemics in main wheat‐cultivating areas of China. High diversity, recombination signatures and inter‐epidemic region migration patterns need to be considered in host‐resistant cultivar development in China and neighbouring countries, considering risk of long‐distance migration capacity of pathogen.

Potential and Distribution of Natural Gas Hydrate Resources in the South China Sea - Pibo Su; Lin Lin; Yaoyao Lv; Jinqiang Liang; Yunbao Sun; Wei Zhang; Huice He; Baiquan Yan; Zhanhuai Ji; Lifeng Wang; Feifei Wang; Mengya Cai (Journal of Marine Science and Engineering, 2022)
The amount of natural gas contained in the world’s gas hydrate accumulations is enormous, but these estimates remain highly speculative. So far, it is still challenging to locate spatial distribution of marine gas hydrate and quantitatively characterize the evaluation parameters and systematic improvement of evaluation systems. Considering the systematic review of the key accumulation factors, such as heat flow, deposition rate and total organic carbon in the typical passive continental margin, the evaluation results of global marine gas hydrate resources were analyzed based on the characteristics of gas hydrate geology, geophysics and geochemistry anomalies in the South China Sea. We analyze the problems on the evaluation of marine gas hydrate resources, probing into the geological characteristics and distribution laws of marine gas hydrate resources in the South China Sea, and estimate the parameters for in-place resource evaluation, in which the volume method based on Monte Carlo probability was used to evaluate the gas hydrate potential resources in the South China Sea. The probability distribution ranges from 37.6 billion (with 90% probability) to 117.7 billion (with 10% probability) tons of oil equivalent, with an expected value of 74.4 billion tons of oil equivalent. The study results show that the gas hydrate resource density in the South China Sea is similar to that in the typical sea areas, and the estimated global resources are basically consistent with the assessment results at this stag; this shows that the South China Sea has great potential for gas hydrate resources. The research results can provide guidance for the evaluation of global climate change and the exploration and development of hydrate resources.

Corrigendum: Effects of dietary glycerol monolaurate on growth, antioxidant capacity and lipid metabolism in cage-farmed pompano (Trachinotus ovatus) juveniles - Huaxing Lin; Beiping Tan; Qihui Yang; Shuyan Chi; Hongjie Wei; Yuancai Wu; Gyan Watson Ray; Mpwaga Alatwinusa Yohana (Frontiers in Marine Science, 2022)

Cavitation–Silt Erosion Behavior and Failure Mechanism of an HVOF-Sprayed WC-Cr3C2-Ni Coating for Offshore Hydraulic Machinery - Jinran Lin; Sheng Hong; Yuan Zheng; Wei Sun; Zhengwei Zhang; Min Kang; Xiuqing Fu (Journal of Marine Science and Engineering, 2022)
WC-Cr3C2-Ni coatings are a vital class of hard ceramic/cermet coatings with potential applications as wear-resistant materials. However, their erosion wear behavior in 3.5 wt.% sodium chloride medium (SCM) remains largely unexplored. The present study investigated the cavitation–silt erosion (CSE) behavior in 3.5 wt.% SCM of WC-Cr3C2-Ni coatings sprayed with high-velocity oxygen–fuel (HVOF) under different flow velocities (FVs) and sand concentrations (SCs). Comparing the WC-Cr3C2-Ni coating with the 1Cr18Ni9Ti stainless steel, the first possessed superior CSE resistance in 3.5 wt.% SCM in a full range of FV and SC. Meanwhile, the coating appeared more influenced by FV and less influenced by SC, which was indicated by the fact that the amplification of VLR value (377.1%) when the FV ranged from 23.4 to 41.9 m·s−1 was larger than that (129.8%) when the SC increased from 10 kg·m−3 to 35 kg·m−3. With increasing FV and SC, the CSE process of the WC-Cr3C2-Ni coating in 3.5 wt.% SCM mainly included the discontinuous corrosion product films, erosion pits, fracturing of hard-phase grains, and micro-cutting of soft binder matrix, as well as crater formation and coating spalling.

Gregarious larval settlement mediates the responses of new recruits of the reef coral Acropora austera to ocean warming and acidification - Lei Jiang; Yu-Yang Zhang; Cheng-Yue Liu; Lin-Tao Huang; Hao-Ya Tong; Guo-Wei Zhou; Ming-Lan Guo; Tao Yuan; Hui Huang (Frontiers in Marine Science, 2022)
Gregarious larval settlement represents an important window for chimera formation in reef corals, yet it remains largely unknown how aggregated settlement and early chimerism could modify the performance and responses of coral recruits under elevated temperature and p CO 2 . In this study, single and aggregated recruits of the broadcast spawning coral Acropora austera were exposed to contrasts of two temperatures (28 versus 30.5°C) and p CO 2 levels (~500 versus 1000 μatm) for two weeks, and algal symbiont infection success, survivorship and growth were assessed. Results showed that symbiont infection success was mainly affected by temperature and recruit type, with reduced symbiont infection at increased temperature and consistently higher infection success in chimeric recruits compared to single recruits. Furthermore, although chimeric recruits with larger areal size had significantly higher survivorship in all treatments, the polyp-specific growth rates were considerably lower in chimeric entities than individual recruits. More importantly, the recruit type significantly influenced the responses of recruit polyp-specific growth rates to elevated temperature, with chimeras exhibiting lowered skeletal lateral growth under elevated temperature. These results demonstrate the benefits and costs associated with gregarious larval settlement for juvenile corals under ocean warming and acidification, and highlight the ecological role of larval settlement behavior in mediating the responses of coral recruits to climate change stressors.

Residual analysis of QoI fungicides in multiple (six) types of aquatic organisms by UPLC-MS/MS under acutely toxic conditions - Hong Li; Shuai Hu; Fengshou Sun; Qi Sun; Ning Wang; Beixing Li; Nan Zou; Jin Lin; Wei Mu; Xiuyu Pang (Environmental Science and Pollution Research, 2022)

Functional analysis of HADH c.99C>G shows that the variant causes the proliferation of pancreatic islets and leu-sensitive hyperinsulinaemia - Wu Long; Yue-Bing Wang; Peng-Fei Qu; Lin Ma; Si-Jie Wei; Yan-Mei Xi; Jin-Liang Du; Xue Tang; Kai Liu; Yu-Hua Li; Pu-Ping Lei (Journal of Genetics, 2022)

Editorial: Carbon storage by marine microorganisms for carbon neutrality - Zhili He; Lu Lin; Xin Wang; Wei Qin; Chuanlun Zhang (Frontiers in Marine Science, 2022)

Effect modification by aging on the associations of nicotine exposure with cognitive impairment among Chinese elderly - Jian Hou; Chao Huang; Bo Zhu; Wei Liu; Qing-qing Zhu; Lu Wang; Tian Li; Chun-jie Yuan; Shao-yang Lai; De-sheng Wu; Fei-qi Zhu; Jia-fei Zhang; et al. (Environmental Science and Pollution Research, 2022)

Shallow-water hydrothermal vent system as an extreme proxy for discovery of microbiome significance in a crustacean holobiont - Ling Chiu; Min-Chen Wang; Kuang-Yu Tseng; Chih-Lin Wei; Huei-Ting Lin; Shan-Hua Yang; Yung-Che Tseng (Frontiers in Marine Science, 2022)
The shallow-water hydrothermal vent (HV) system off Kueishan Island lies at the end of the Okinawa Trough to the northeast of Taiwan. Near its submarine vent openings, aperiodic vent discharges generate a dynamic acidic (pH 5.5-8.1) and sulfidic (9-3000 μM) ecosystem. The dominant metazoan in this unique environment is the brachyuran vent crab, Xenograpsus testudinatus , which has developed robust metabolic strategies and highly adaptive acid-base regulatory mechanisms to maintain its physiological homeostasis. X. testudinatus is considered a holobiont, but the symbiotic mechanisms underlying acid and sulfur tolerance in the host-microbe system remain largely unclear. In this study, we used LoopSeq long-read sequencing of the full-length 16S rRNA gene to identify the bacterial communities present in the gills and carapace surface of X. testudinatus . The alpha diversity analysis, Venn diagram, and principal coordinate analysis (PCoA) indicated that the gills and carapace surface exhibit different bacterial constituents. Further measurements of relative abundance, coupled with functional predictions and fluorescence in situ hybridization (FISH), revealed a predominance of Sulfurovum sp. NBC37-1, a key bacterium that can perform sulfur and hydrogen oxidation to support denitrification processes. Consequently, our findings suggest that the symbiotic bacteria may play a critical role in conferring the extraordinary acid and sulfur tolerances of X. testudinatus , allowing the crustacean holobiont to thrive in its ecological niche within one of the most extreme marine habitats on Earth.

Studying bona fide SARS-CoV-2 biology in a BSL-2 biosafety environment using a split-virus-genome system - Yingxin Ma; Guobin Mao; Weishan Yang; Guoqiang Wu; Guoqiang Li; Xiaoying Li; Xin Lin; Junnan Lu; Shijun Zhao; Wei Zhao; Junbiao Dai; Xian-En Zhang (Science China Life Sciences, 2022)

The role of MeCP2 and the BDNF/TrkB signaling pathway in the stress resilience of mice subjected to CSDS - Lixuan Huang; Lujuan He; Ruijia Ma; Wanzhao Ding; Chan Zhou; Song Lin; Ji-chun Zhang; Jiaxu Chen; Wei Yao (Psychopharmacology, 2022)

Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia - Kang-Wei Qian; Yun-Yun Li; Xiao-Hua Wu; Xue Gong; Ai-Lin Liu; Wen-Hao Chen; Zhe Yang; Ling-Jie Cui; Yun-Feng Liu; Yuan-Yuan Ma; Chen-Xi Yu; Furong Huang; et al. (Neuroscience Bulletin, 2022)

p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia - Houmin Lin; Steven Grant Dixon; Wei Hu; Eric D. Hamlett; Junfei Jin; Adviye Ergul; Gavin Y. Wang (Molecular Neurobiology, 2022)

Validity Analysis of the Morphological Identification of Three Highly Morphologically Similar Species Belonging to the Genus Niviventer (Rodentia: Muridae) - Yao-Yao Li; Hao-Tian Li; Jia-Wei Hao; Chen-Yi Zhang; Guan-Ze Liu; Xing-Han Lin; Xiao-Qing Sun; Guo-Chen Zang; Yu-Chun Li (Journal of Mammalian Evolution, 2022)

Environmental decentralization, environmental public service, and public health: evidence from 289 cities in China - Huimin Ma; Danyang Di; Lin Li; Wei Zhang; Jianmei Wang (Environmental Geochemistry and Health, 2022)

Identification and QTL mapping of important agronomic traits based on rice short-wide grain CSSL-Z752 with restorer line Xihui 18 as background - Lin-Jun Cai; Han Yun; Xiao-Long Zhong; Dan Du; Xi-Man Peng; Ji-Chao Dai; Zhen-Lin Yang; Fang-Ming Zhao; Chang-Wei Zhang (Cereal Research Communications, 2022)

Paleo-karst zone and its control on reservoirs in the fourth member of the Sinian Dengying formation in the Moxi area, central Sichuan Basin - Qinyu Xia; Haijun Yan; Wei Xu; Lin Zhang; Qian Li; Wenjun Luo; Hui Deng; Xun Zhu; Xinyu Li; Jichen Yu (Carbonates and Evaporites, 2022)

Geomechanics model test and numerical simulation of 2G-NPR bolt support effect in an active fault tunnel - Shu-lin Ren; Man-chao He; Wei-jun Lin; Teng-wu Zhang; Zhi-gang Tao (Journal of Mountain Science, 2022)

Insulin growth factor-1 enhances proliferation and inhibits apoptosis of neural progenitor cells by phosphorylation of Akt/mTOR/p70S6K molecules and triggering intrinsic apoptosis signaling pathway - Bo Zhang; Lingyun Hu; Jianying Zhang; Hui Wu; Wei Li; Lin Gou; Hao Liu (Cell and Tissue Banking, 2022)

Strength and deformation behavior of columnar jointed rock masses under different confining pressures - Zhi-nan Lin; Hai-feng Long; Wei-ya Xu; Ru-bin Wang; Shi-hong Feng (Arabian Journal of Geosciences, 2022)

An integrated analysis of pond ecosystem around Poyang Lake: assessment of water quality, sediment geochemistry, phytoplankton and benthic macroinvertebrates diversity and habitat condition - Wei Liu; Qiyang Tan; Yifan Chu; Jinmei Chen; Lingli Yang; Lin Ma; Yi Zhang; Zhenbin Wu; Feng He (Aquatic Ecology, 2022)

Cluster analysis of the domain of microseismic event attributes for floor water inrush warning in the working face - Guo-Jun Shang; Xiao-Fei Liu; Li Li; Li-Song Zhao; Jin-Song Shen; Wei-Lin Huang (Applied Geophysics, 2022)

Vibrio salinus sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll in the western Pacific Ocean - Wei-Sheng Huang; Li-Ting Wang; Jwo-Sheng Chen; Yen-Ting Chen; Sean Ting-Shyang Wei; Yin-Ru Chiang; Pei-Ling Wang; Tzong-Huei Lee; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2022)

Coastal aquaculture farms for the sea cucumber Apostichopus japonicus provide spawning and first-year nursery grounds for wild black rockfish, Sebastes schlegelii: A case study from the Luanhe River estuary, Bohai bay, the Bohai Sea, China - Min Xu; Zun-li Qi; Zun-lei Liu; Wei-min Quan; Qi Zhao; Yun-ling Zhang; Hui Liu; Lin-lin Yang (Frontiers in Marine Science, 2022)
Aquaculture farms are known to attract wild organisms from nearby areas. Sea cucumber Apostichopus japonicus aquaculture farms in Bohai Bay, the Bohai Sea, China, might provide spawning and nursery grounds for wild black rockfish Sebastes schlegelii populations. To identify the above, we studied the variation in the numbers of S. schlegelii larvae (and length-categories as a percentage of the natural population) via ichthyoplankton surveys by months from January to October 2020, and assessed the food web structure and energy flow distribution of the farm and trophic links of S. schlegelii natural stock by using Ecopath modeling in July 2016 to August 2017. Larvae with a length between 3.90-5.80 mm were observed in the farm in May 2020, the juveniles with an estimated trophic level of 4.31. Juveniles used the farms as first-year nursery ground, and then they swam into deeper waters in August of the following year. MTI analysis showed increasing biomass of S. schlegelii might result in a decrease in the biomass of crustacea, and had positive and negative impacts on mollusk and Hexagrammos otakii biomass. We argued that aquacultural infrastructures constructed by artificial reefs could be used as a fisheries management tool to enhance S. schlegelii stocks and that monitoring of other marine organisms, such as oysters, Rapana venosa , Charybdis japonica , and Asterias spp. etc., was necessary to maintain sustainable exploitations of aquacultural farm ecosystems. A paucity of knowledge surrounding the interactions between aquaculture farms and wild organisms needs furthermore researches.

Hydrodynamic effects of large-scale suspended mussel farms: Field observations and numerical simulations - Wei Zhong; Jun Lin; Qingping Zou; Ying Wen; Wei Yang; Guanlin Yang (Frontiers in Marine Science, 2022)
The hydrodynamic effects of the largest suspended mussel farms in the East China Sea near Gouqi Island, was investigated using a high-resolution 3D ocean model and field observations. To capture the 3D farm effects on hydrodynamics, an additional depth dependent momentum sink term was introduced in the model. The model results compared well with the field observations. The present model and observational results indicate that the presence of farms reduces the flow by more than 79%, 55%, and 34% in the upper, middle, and bottom layers at the farm center, respectively. According to the harmonic analysis of predicted current, mussel farms reduce the magnitude of the semidiurnal tidal current and also alter the magnitude and direction of the diurnal tidal current. The blockage by the farm weakens the Eulerian residual tidal current within the farm in the NE-SW direction, while strengthens that at the edge of the farm in the SE-NW direction. Cross sections, Sec1 and Sec2 are perpendicular to these two major residual currents and intercept with the center of the farm from SE to NW and from NE to SW respectively. The farm effect on the total water flux over a month through the Sec2 displays a semi-lunar periodic oscillation and is one order of magnitude smaller than that at Sec1. An asymmetry tidal current was observed in the farm north of Gouqi Island. The field observation of vertical profiles of current suggests that the thickness of surface canopy boundary layer can reach 5 m upstream from the farm during flood tide, increases gradually downstream up to 10 m under the cumulative influences of the farm. And a wake zone was observed downstream from the farm during flood tide. Better understanding of farm-induced hydrodynamic effects provides insight into how to optimize farm layouts based on local hydrodynamics, to maximize farm productivity and minimize environmental impacts.

Petrogenesis of Eocene mafic and felsic magmas in the New Caledonia ophiolite: geochemistry and geochronology constraints - Yang Xu; Chuan-Zhou Liu; Xue-Fa Shi; Wei Lin (International Geology Review, 2022)

Mapping the potential for offshore aquaculture of salmonids in the Yellow Sea - Shuang-En Yu; Shuang-Lin Dong; Zhi-Xin Zhang; Yu-Yang Zhang; Gianluca Sarà; Jie Wang; Yun-Wei Dong (Marine Life Science & Technology, 2022)
Mariculture has been one of the fastest-growing global food production sectors over the past three decades. With the congestion of space and deterioration of the environment in coastal regions, offshore aquaculture has gained increasing attention. Atlantic salmon ( Salmo salar ) and rainbow trout ( Oncorhynchus mykiss ) are two important aquaculture species and contribute to 6.1% of world aquaculture production of finfish. In the present study, we established species distribution models (SDMs) to identify the potential areas for offshore aquaculture of these two cold-water fish species considering the mesoscale spatio-temporal thermal heterogeneity of the Yellow Sea. The values of the area under the curve (AUC) and the true skill statistic (TSS) showed good model performance. The suitability index (SI), which was used in this study to quantitatively assess potential offshore aquaculture sites, was highly dynamic at the surface water layer. However, high SI values occurred throughout the year at deeper water layers. The potential aquaculture areas for S. salar and O. mykiss in the Yellow Sea were estimated as 52,270 ± 3275 (95% confidence interval, CI) and 146,831 ± 15,023 km 2 , respectively. Our results highlighted the use of SDMs in identifying potential aquaculture areas based on environmental variables. Considering the thermal heterogeneity of the environment, this study suggested that offshore aquaculture for Atlantic salmon and rainbow trout was feasible in the Yellow Sea by adopting new technologies (e.g., sinking cages into deep water) to avoid damage from high temperatures in summer.

Application of the Non-dominated Sorting Genetic Algorithm II in Multi-objective Optimization of Orally Disintegrating Tablet Formulation - Jiaqi Zhang; Yu Yao; Wei Sun; Liling Tang; Xiaodong Li; Huaqing Lin (AAPS PharmSciTech, 2022)

Natural variation of the BRD2 allele affects plant height and grain size in rice - Jinpeng Huang; Zhiming Chen; Jiajia Lin; Jinwen Chen; Menghao Wei; Liang Liu; Feng Yu; Zesen Zhang; Fangyu Chen; Liangrong Jiang; Jingsheng Zheng; Tiansheng Wang; et al. (Planta, 2022)

AFD-Net: Apple Foliar Disease multi classification using deep learning on plant pathology dataset - Anju Yadav; Udit Thakur; Rahul Saxena; Vipin Pal; Vikrant Bhateja; Jerry Chun-Wei Lin (Plant and Soil, 2022)
Background Plant diseases significantly affect the crop, so their identification is very important. Correct identification of these diseases is crucial for establishing a good disease control strategy to avoid time and financial losses. In general, machines can greatly reduce the possibility of human error. In particular, computer vision techniques developed through deep learning have paved a way to detect and diagnose these plant diseases on the leaf. Methods In this work, the model AFD-Net was developed to detect and identify various leaf diseases in apple trees. The dataset is from Kaggle 2020 and 2021 and was financially supported by the Cornell Initiative for Digital Agriculture. An AFD-Net was proposed for leaf disease classification in apple trees and the results of the efficiency of the model are compared with other state-of-the-art deep learning approaches. Results The results of the experiments in the validation dataset show that the proposed AFD-Net model achieves the highest values of 98.7% accuracy for Plant Pathology 2020 and 92.6% for Plant Pathology 2021 compared to other deep learning models in the original and extended datasets. Discussion The results also indicate the efficiency of the proposed model in identifying leaf diseases on apple trees for major and minor classes, i.e., for multiple classification.

A strategy for establishing an efficient somatic embryo regeneration system in Castanea mollissima Blume - Xiao-wei Li; Zhi-lin Sun; Yue-rong Gao; Jing-yi Ge; Yu-zhen Tian; Bing Liu; Shi-kan Sun; Ke-feng Fang; Ling Qin; Qing-qin Cao (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Environmental indicators combined with risk analysis to evaluate potential wildfire incidence on the Dadu Plateau in Taiwan - Chao-Yuan Lin; Pei-Ying Shieh; Shao-Wei Wu; Po-Cheng Wang; Yung-Chau Chen (Natural Hazards, 2022)
Wildfire is a common disaster in the world, and it has a considerable impact on the safety of residents and ecological disturbance. Periodic wildfires are an urgent problem to be solved. This research uses big data from relevant departments to extract environmental indicators that affect wildfires, including satellite images, meteorological observations, and field surveys and establishes a risk model for the Spatio-temporal distribution of wildfires based on risk analysis. Previous studies using Differenced Normalized Burn Ratio (dNBR) to assess fire severity and distinguish wildfire ruins did not deal with the impact of atmospheric humidity on dNBR values. In this study, an adjustable fire threshold was developed to enable dNBR to improve the accuracy of identifying wildfire locations. Regarding the temporal distribution of wildfire risks, environmental vulnerability cannot specifically reflect the frequency of actual wildfires. If the hazard degree is introduced to calculate the wildfire risk, the coefficient of determination can be increased from 0.49 to 0.79. The verification of the village boundary zone depicts that the risk analysis can effectively show the temporal and spatial distribution of wildfire hotspots. On this basis, a village-level wildfire disaster prevention strategy can be formulated.

Correction to: Exosome-Derived lncRNA NEAT1 Exacerbates Sepsis-Associated Encephalopathy by Promoting Ferroptosis Through Regulating miR-9-5p/ TFRC and GOT1 Axis - Xue-biao Wei; Wen-qiang Jiang; Ju-hao Zeng; Lin-qiang Huang; Hong-guang Ding; Yuan-wen Jing; Yong-li Han; Yi-chen Li; Sheng-long Chen (Molecular Neurobiology, 2022)

Activation of the TREK-1 Potassium Channel Improved Cognitive Deficits in a Mouse Model of Alzheimer’s Disease by Modulating Glutamate Metabolism - Fang Li; Shu-ning Zhou; Xin Zeng; Zhen Li; Rui Yang; Xue-xi Wang; Bin Meng; Wei-lin Pei; Li Lu (Molecular Neurobiology, 2022)

Chemical and biological diversity of new natural products from marine sponges: a review (2009–2018) - Li-Li Hong; Ya-Fang Ding; Wei Zhang; Hou-Wen Lin (Marine Life Science & Technology, 2022)
Marine sponges are productive sources of bioactive secondary metabolites with over 200 new compounds isolated each year, contributing 23% of approved marine drugs so far. This review describes statistical research, structural diversity, and pharmacological activity of sponge derived new natural products from 2009 to 2018. Approximately 2762 new metabolites have been reported from 180 genera of sponges this decade, of which the main structural types are alkaloids and terpenoids, accounting for 50% of the total. More than half of new molecules showed biological activities including cytotoxic, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, enzyme inhibition, and antimalarial activities. As summarized in this review, macrolides and peptides had higher proportions of new bioactive compounds in new compounds than other chemical classes. Every chemical class displayed cytotoxicity as the dominant activity. Alkaloids were the major contributors to antibacterial, antifungal, and antioxidant activities while steroids were primarily responsible for pest resistance activity. Alkaloids, terpenoids, and steroids displayed the most diverse biological activities. The statistic research of new compounds by published year, chemical class, sponge taxonomy, and biological activity are presented. Structural novelty and significant bioactivities of some representative compounds are highlighted. Marine sponges are rich sources of novel bioactive compounds and serve as animal hosts for microorganisms, highlighting the undisputed potential of sponges in the marine drugs research and development.

Biomechanical Analysis of Mandibular Implant-Assisted Removable Partial Denture with Distal Extension - Yung-Chung Chen; Chi-Lun Lin; Chen-Han Yu; Hung-Chih Chang; Yang-Ming Lin; Jia-Wei Lin (Journal of Medical and Biological Engineering, 2022)

Biomechanical Effects of Bone Atrophy, Implant Design, and Vertical or Tilted of Posterior Implant on All-on-Four Concept Implantation: Finite Element Analysis - Heng-Li Huang; Ting-Wei Lin; Hui-Ling Tsai; Yu-Ling Wu; Aaron Yu-Jen Wu (Journal of Medical and Biological Engineering, 2022)

Characteristics and comparative analysis of Mesona chinensis Benth chloroplast genome reveals DNA barcode regions for species identification - Danfeng Tang; Yang Lin; Fan Wei; Changqian Quan; Kunhua Wei; Yanyan Wei; Zhongquan Cai; Muhammad Haneef Kashif; Jianhua Miao (Functional & Integrative Genomics, 2022)

Effects of U on the growth, reactive oxygen metabolism and osmotic regulation in radish (Raphanus sativus L.) - Guo Wu; Xi Chen; Ting Zheng; Pi-xian Xiao; Ning-ying Zhong; Xiu-lin Yang; Yi Li; Wei Li (Environmental Science and Pollution Research, 2022)

Correction to: Higher sequestration of wheat versus maize crop carbon in soil under rotations - Zheng-Rong Kan; Shou-Wei Han; Wen-Xuan Liu; Xin Zhao; Rattan Lal; Hai-Lin Zhang (Environmental Chemistry Letters, 2022)

The time-varying networks of the wrist extension in post-stroke hemiplegic patients - Fali Li; Lin Jiang; Yangsong Zhang; Dongfeng Huang; Xijun Wei; Yuanling Jiang; Dezhong Yao; Peng Xu; Hai Li (Cognitive Neurodynamics, 2022)

Association of cognitive impairment and reduced cortical thickness in prefrontal cortex and anterior cingulate cortex with treatment-resistant depression - Mu-Hong Chen; Wan-Chen Chang; Pei-Chi Tu; Wei-Chen Lin; Cheng-Ta Li; Wen-Sheng Huang; Ya-Mei Bai; Shih-Jen Tsai; Tung-Ping Su (Brain Imaging and Behavior, 2022)

Estimation of time to progression and post progression survival using joint modeling of summary level OS and PFS data with an ordinary differential equation model - Mario Nagase; Sameer Doshi; Sandeep Dutta; Chih-Wei Lin (Journal of Pharmacokinetics and Pharmacodynamics, 2022)

Preliminary study of genome-wide association identified novel susceptibility genes for thyroid-related hormones in Chinese population - Liang Huang; Fenghua Bai; Yutian Zhang; Shanshan Zhang; Tianbo Jin; Xingwei Wei; Xiaoli Zhou; Mei Lin; Yufei Xie; Chanyi He; Qi Lin; Tian Xie; et al. (Genes & Genomics, 2022)

Lelliottia steviae sp. nov. isolated from Stevia rebaudiana Bertoni - Jing Lin; Ke Huang; Jing-Yu Huang; Yuan-Ru Xiong; Meng-Meng Wei; Na Xiao; Jia Gao; Xuan-Kai Ding; Zi-Yang Ma; Jun-Hao Sang; Ling-Xian Kong; Zhi-Yun Hong; et al. (Archives of Microbiology, 2022)

Protein kinase Ime2 is associated with mycelial growth, conidiation, osmoregulation, and pathogenicity in Fusarium oxysporum - Jiling Xiao; Yi Zhang; Ke Yang; Yanying Tang; Lin Wei; Erming Liu; Zhihuai Liang (Archives of Microbiology, 2022)
Fusarium oxysporum f.sp. niveum is one of the most serious diseases impairing watermelon yield and quality. Inducer of meiosis 2 (Ime2) is the founding member of a family of serine/threonine protein kinases and plays important roles in yeasts and other filamentous fungi. In this study, we analyzed the functions of Fo Ime2, the ortholog of Saccharomyces cerevisiae Ime2 in F. oxysporum f.sp. niveum . The FoIme2 -deleted mutants exhibited obvious morphological abnormalities, including slower vegetative growth, more branches in the edge hyphae and a reduction in conidia production. Compared to the wild type, the mutants were hypersensitive to the osmotic stressor NaCl but were more insensitive to the membrane stressor SDS. The deletion of FoIme2 also caused a reduction in pathogenicity. Transcriptional analysis revealed that Fo Ime2 acts downstream of Fo Opy2 which is an upstream sensor of the MAPK kinase cascade. These results indicate that Fo Ime2 is important in the development and pathogenicity of F. oxysporum, and provide new insight for the analysis of the pathogenic mechanism of F. oxysporum.

Montreal Cognitive Assessment of cognitive dysfunction after basal ganglia stroke - Baoye Ye; Dingqun Wei; Lin Pan (Acta Neurologica Belgica, 2022)
Objective The Montreal Cognitive Assessment (MoCA) was used to evaluate cognitive dysfunction after basal ganglia stroke, and factors affecting total MoCA score were examined. Methods Data were retrospectively analyzed for 30 patients with basal ganglia intracerebral hemorrhage or basal ganglia cerebral infarction, who were admitted to The Second Affiliated Hospital of Fujian Traditional Medical University (Fujian, China) from January 2017 to March 2020. Cognitive impairment was assessed using the MoCA, and potential correlations were explored between clinicodemographic characteristics (sex, age, stroke location and etiology) and MoCA dimensions or total MoCA score. Results Univariate linear regression showed that the total MoCA score was significantly associated with sex, age, executive function, naming, attention, abstract generalization ability, memory ability, and visuospatial orientation. However, multivariate linear regression identified only executive function, naming, attention, memory ability, and visuospatial orientation as significantly associated with the total MoCA score. Conclusions We showed that the MoCA test can be used for patients with basal ganglia stroke. The total MoCA score of basal ganglia stroke was significantly associated with impairments in executive function, naming, attention, memory ability, and visuospatial orientation.

Assessing the effect of probiotics on tilapia lake virus‐infected tilapia: Transmission and immune response - Ying‐Fei Yang; Jidapa Yamkasem; Win Surachetpong; Yi‐Jun Lin; Shu‐Han You; Tien‐Hsuan Lu; Chi‐Yun Chen; Wei‐Min Wang; Chung‐Min Liao (Journal of Fish Diseases, 2022)
Probiotics have been used to alleviate disease transmission in aquaculture. However, there are limited studies on probiotic use in modulating tilapia lake virus (TiLV). We assessed commercially available probiotic supplements used in TiLV‐infected tilapia and performed mortality and cohabitation assays. We developed a mechanistic approach to predict dose–response interactions of probiotic effects on mortality and immune gene response. We used a susceptible–infected–mortality disease model to assess key epidemiological parameters such as transmission rate and basic reproduction number ( R 0 ) based on our viral load dynamic data. We found that the most marked benefits of probiotics are significantly associated with immune system enhancements (~30%) and reductions in disease transmission (~80%) and R 0 (~70%) in tilapia populations, resulting in a higher tolerance of farming densities (~400 fold) in aquaculture. These findings provide early insights as to how probiotic use‐related factors may influence TiLV transmission and the immune responses in TiLV‐infected tilapia. Our study facilitates understanding the mode of action of probiotics in disease containment and predicting better probiotic dosages in diet and supplements to achieve the optimal culturing conditions. Overall, our analysis assures that further study of rationally designed and targeted probiotics, or mechanistic modelling is warranted on the basis of promising early data of this approach.

Habitat change and its consequences on reef fish specialization in biogeographic transition zones - Yuting Vicky Lin; Wanchien Victoria Hsiao; Wei‐Jen Chen; Vianney Denis (Journal of Biogeography, 2022)
Aim Reef fishes are commonly recognized as sentinels of the ongoing tropicalization in biogeographic transition zones between temperate and tropical areas. Despite the reliance of these marine ectotherms on the benthos, the importance of benthic habitat has rarely been considered as a factor constraining fish distribution. Therefore, our study aims at examining the consequences of both temperature and benthic variations on the fish fauna and diagnosing potential sentinels of these environmental changes. Location Taiwan, West Pacific. Taxon Teleostei (184 species). Methods We examined how the partitioning of habitats can influence the specialization of fish fauna along a latitudinal gradient. We diagnosed ‘specialist’ and ‘generalist’ fishes in this partitioning. For each specialist, we further evaluated whether its distribution is constrained by temperature, benthic habitat or both factors combined. The change in sea surface temperature over the last three decades was also monitored. Results Fish fauna showed the highest specialization when tropical and subtropical partitions of habitat were considered. Fifty‐one tropical specialists, 7 subtropical specialists and 21 possible generalists were identified. Among specialists, 13 species were associated with temperature, 19 with habitat and 26 with both factors. Steady warming occurred across latitudes, but was accentuated in the winter of subtropical habitat. Main Conclusions Our results suggested that the distribution of some specialist fishes was constrained only by temperature while the distribution of some others also depended on the availability of benthic habitats. Consequently, under global warming, the distribution of some specialists might shift in a manner that follows the movement of isotherms, while the distribution of others might also be conditioned by the poleward shifts of benthos. A temporal mismatch between the emergence of suitable thermal environments and the arrival of some specialists may exist. Therefore, the tropicalization of high‐latitude areas may be characterized by different waves of colonization.

To cheat or to treat? Fungus gnat pollination in Aspidistra - Wei Lin; Yuanqing Xu; Yuhui Jiang; Zhonghui Ma (Ecology, 2022)

Analysis of Influencing Factors of SST in Tropical West Indian Ocean Based on COBE Satellite Data - Chaoli Tang; Dewei Hao; Yuanyuan Wei; Fengmei Zhao; Han Lin; Xin Wu (Journal of Marine Science and Engineering, 2022)
The time-frequency domain analysis of the sea surface temperature (SST) in the tropical western Indian Ocean was conducted using wavelet analysis, cross wavelet transform (XWT), the Mann–Kendall (MK) test, and other methods based on COBE-SST data for the last 50 years (1974–2020). From the perspective of time-frequency combination, examining the data of precipitation, sea surface heat flux, total cloud cover, and long-wave radiation, helped contribute to exploring the periodic changes of SST. Moreover, the Western Hemisphere Warm Pool (WHWP) was selected to analyze the role of SST from 1974 to 2020. Present results have demonstrated that the SST in the western Indian Ocean was in a stage of rising, particularly in 1998. According to the fast Fourier transform of the filtered SST time series, the tropical western Indian Ocean SST has a short period of 3–6 years, a medium period of about 10 years, and a long period of 40 years. The SST in the tropical western Indian Ocean has a resonance period of 2–6 years with precipitation, a resonance period of 2–6 years with sea surface heat flux, a resonance period of 4–5 years with total cloud cover, and a resonance period of 2–5 years with long-wave radiation. Importantly, SST was negatively associated with precipitation, total cloud cover, and long-wave radiation, and positively for sea surface heat flux before 1997. Seasonal migration activities are significantly correlated with the WHWP and the tropical western Indian Ocean SST. The spatial lattice point correlation coefficient is generally from 0.6 to 0.9, and the inter-annual serial correlation value is more than 0.89. Furthermore, the two exist with a resonance period of 2–5 years.

Characterization of Fine-Scale Turbulence Generated in a Laboratory Orbital Shaker and Its Influence on Skeletonema costatum - Lin Yu; Yifan Li; Zhongzhi Yao; Long You; Zong-Pei Jiang; Wei Fan; Yiwen Pan (Journal of Marine Science and Engineering, 2022)
Turbulence is one of the ubiquitous aspects of aquatic systems and affects many physical and biological processes. Based on direct velocity measurements and a computational fluid dynamics (CFD) simulation, we characterized the distribution of the turbulent kinetic dissipations rates (ε) in an orbital shaker system within a range of rotation frequencies. CFD was able to estimate the ε distribution in containers accurately, which was confirmed by other two methods and was independent of velocity measurement. The results showed that ε was linearly correlated with the rotational frequencies. Despite the existence of gradients of ε and the fact that a mean circular horizontal flow was formed within the tank, the energy levels of the whole tank varied spatially within an order of magnitude and the ε distributions at different rotational frequencies were similar, suggesting that the ε distribution in the whole tank could be seen as quasi-homogeneous. To investigate the influence of turbulence on algae growth, culture experiments of a typical diatom—Skeletonema costatum were carried out under different turbulence conditions. Our results suggested turbulence mixing promoted nutrient uptake and growth of Skeletonema costatum, which could be attributed to the break of the diffusion-limited resource concentration boundary layer surrounding phytoplankton.

Recognition of behavior state of Penaeus vannamei based on passive acoustic technology - Maochun Wei; Keyu Chen; Yating Lin; En Cheng (Frontiers in Marine Science, 2022)
Underwater signal processing based on passive acoustic technology has carried out a lot of research on the behavioral sound of underwater creatures and the protection of marine resources, which proves the feasibility of passive acoustic technology for long-term and non-destructive monitoring of underwater biological sound production. However, at present, most relevant research focuses on fish but little research on shrimp. At the same time, as the main economic breeding industry, Penaeus vannamei has a backward industrial structure, in which the level of intelligence needs to be improved. In this paper, the acoustic signals generated by different physiological behaviors of P. vannamei are collected based on passive acoustic technology. Their different behaviors are finally classified and identified through feature extraction and analysis. Meanwhile, the characteristic non-parametric ANOVA is carried out to explore the relationship between the acoustic signals and the behavior state of P. vannamei to achieve the purpose of real-time monitoring of the behavior state of P. vannamei . The experimental results show that linear prediction cepstrum coefficient (LPCC) and Mel-frequency cepstrum coefficient (MFCC) characteristic coefficients are effective in the classification and recognition of different behavioral acoustic signals with interspecific acoustic signals of P. vannamei . Meanwhile, the SVM classifier based on OvR classification strategy can model the acoustic signal characteristics of different underwater biological behaviors more efficiently and has classification accuracy as high as 93%.

High animal protein diet and gut microbiota in human health - Jie Cai; Zhongxu Chen; Wei Wu; Qinlu Lin; Ying Liang (Critical Reviews in Food Science and Nutrition, 2022)

Isolation and identification of two new sargentodoxosides from Sargentodoxa cuneata and their agonistic effects against FXR - Wen Zhang; Cheng-Peng Sun; Yu-Lin Peng; Wen-Yu Zhao; Zheng-Yue Wang; Jing Ning; Xia Lv; Zhen-Long Yu; Shuang Zhou; Wei Peng; Bang-Jiang Fang; Xiao-Chi Ma (Natural Product Research, 2022)

The Spatial Variation in Chlorophyte Community Composition From Coastal to Offshore Waters in a Subtropical Continental Shelf System - Yun-Chi Lin; Chien-Pang Chin; Wei-Ting Chen; Ching-Ting Huang; Gwo-Ching Gong; Kuo-Ping Chiang; Xin-Bei Chen (Frontiers in Marine Science, 2022)
Globally, the continental shelf occupies less than 10% of the total sea surface, but supports substantial primary production and fisheries. Photosynthetic picoeukaryotes (PPE) are important primary producers in marine ecosystems, and chlorophytes make a significant contribution to PPE abundance. Although the distribution of chlorophytes has been widely studied, little is known about how their community composition varies along the coastal-offshore gradient in subtropical continental shelf waters. To better understand their spatial variations, we employed metabarcoding data of 18S rRNA V4 gene to examine chlorophyte composition within the surface and deep chlorophyll maximum (DCM) layers over the continental shelf in the East China Sea (ECS) with high-resolution sampling. Our results indicate a higher chlorophyte diversity in the surface layer than in the DCM. In addition, we found that chlorophytes in oligotrophic Kuroshio surface water were the most diverse, with a higher percentage of Chloropicophyceae, prasinophyte clade V, prasinophyte clade IX, Palmophyllophyceae and Chlorodendrophyceae. In more eutrophic waters along the coast and within the DCM layer, chlorophytes were dominated by Mamiellophyceae. A significant spatial variation in community composition occurred along the nutrient gradient in the subtropical continental shelf ecosystem, varying from Mamiellophyceae-dominant in coastal water to Chloropicophyceae-dominant in offshore water. Furthermore, at a low saline coastal station, which had the lowest chlorophyte diversity, Picochlorum (Trebouxiophyceae) was dominant. Overall, chlorophyte diversity was positively correlated with temperature, and negatively correlated with silicate concentration. This study revealed that terrestrial input into continental systems influences chlorophyte diversity in the subtropical northwestern Pacific Ocean.

Effects of Dietary Glycerol Monolaurate on Growth, Antioxidant Capacity and Lipid Metabolism in Cage-Farmed Pompano (Trachinotus ovatus) Juveniles - Huaxing Lin; Beiping Tan; Qihui Yang; Shuyan Chi; Hongjie Wei; Yuancai Wu; Gyan Watson Ray; Mpwaga Alatwinusa Yohana (Frontiers in Marine Science, 2022)
Glycerol monolaurate (GML), a representative fatty acid glyceride, was used to promote growth. This study investigated the effects of GML in diets on growth, serum biochemical parameters, antioxidant capacity, liver morphology and lipid metabolism for juvenile pompano Trachinotus ovatus . Six groups of T. ovatus (mean weight = 14.00 ± 0.70 g) were fed with six diets, containing varying GML levels of 0.00% (G0), 0.05% (G5), 0.10% (G10), 0.15% (G15), 0.20% (G20), and 0.25% (G25) for 8 weeks. Fish were reared for in floating cages (length: 1 m; width: 1 m; and height: 2 m). The highest weight gain rate (WGR), specific growth rate (SGR), and protein deposit rate (PDR) were observed in the G15 group ( P < 0.05). Hepatic glutathione peroxidase, total antioxidant capacity and superoxide dismutase activities were significantly increased in the G10 and G15 groups compared with the G0 group ( P < 0.05), whereas hepatic malondialdehyde (MDA) was significantly reduced in the G10 and G15 groups ( P < 0.05). The alkaline phosphatase activity was significantly higher in the G5, G10, G15, and G20 groups than in the G0 group ( P < 0.05), and the highest AKP activity was observed in the G15 group. Alanine aminotransferase (ALT) activity was significantly lower in the G10, G15, G20, and G25 groups than in the G0 group ( P < 0.05). The addition of GML to the feed significantly reduced triglyceride (TG) content ( P < 0.05). In comparison with the G0 group, the G15, G20, and G25 groups had significantly lower total cholesterol content and significantly higher high-density lipoprotein content ( P < 0.05). Low-density lipoprotein content was significantly lower in the G5 and G10 groups than in the G0 group ( P < 0.05). Serious vacuolation occurred in the G0 group, but the cell boundaries in all added groups were obvious, and the rate of intracellular vacuolization decreased. As the GML level increased, carnitine palmitoyl-transferase Ι mRNA level was significantly up-regulated ( P < 0.05). The expression of fatty acid synthesis in the G10, G15, G20, and G25 groups was significantly lower than that in the G0 group ( P < 0.05). The expression of sterol regulatory element-binding protein-Ι was significantly lower in the G10, G15, G20, and G25 groups than in the G0 group ( P < 0.05). Based on the broken-line model of WGR and PDR corresponding to GML levels, the optimum addition level of dietary GML was 0.14%-0.16% for juvenile T. ovatus . In conclusion, 0.15% GML significantly improved the growth performance, hepatic antioxidant ability, and lipid metabolism and protected the liver for juvenile pompano T. ovatus .

Pon1 Deficiency Promotes Trem2 Pathway–Mediated Microglial Phagocytosis and Inhibits Pro-inflammatory Cytokines Release In Vitro and In Vivo - Li Zhang; Wei Dong; Yuanwu Ma; Lin Bai; Xu Zhang; Caixian Sun; Jingwen Li; Lianfeng Zhang (Molecular Neurobiology, 2022)

Preliminary establishment of a mass movement warning system for Taiwan using the soil water index - Chi-Wen Chen; Ching Hung; Guan-Wei Lin; Jun-Jih Liou; Shih-Yao Lin; Hsin-Chi Li; Yung-Ming Chen; Hongey Chen (Landslides, 2022)

Diminished miR-374c-5p negatively regulates IL (interleukin)-6 in unexplained recurrent spontaneous abortion - Lin Zhao; Li Han; Guozhen Hei; Ran Wei; Zhen Zhang; Xiaoxiao Zhu; Qiang Guo; Chu Chu; Xiaoxiao Fu; Ke Xu; Xia Li (Journal of Molecular Medicine, 2022)

Effects of pre-oxidation by ozone, permanganate and ferrate on generation and toxicities of disinfection byproducts - Y. Lin; Y. Lou; A. Li; Y. Wei; H. Li; M. Zhou; Y. Li (International Journal of Environmental Science and Technology, 2022)

Construction and comprehensive analysis of a lncRNA–mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development - Chihao Zhang; Wei Ni; Yiming Zhu; Jiayun Lin; Hongjie Li; Zhifeng Zhao; Ke Wang; Haizhong Huo; Meng Luo (Human Cell, 2022)

Associations Between Plasma Metals and Cognitive Function in People Aged 60 and Above - Junling Zhang; Qiumei Liu; Min Xu; Jiansheng Cai; Yanfei Wei; Yinxia Lin; Xiaoting Mo; Shenxiang Huang; Shuzhen Liu; Chunbao Mo; Tingyu Mai; Dechan Tan; et al. (Biological Trace Element Research, 2022)

Integrated small RNA profiling and degradome analysis of Anthurium andraeanum cultivars with different-colored spathes - Fazhuang Lin; Shi-Peng Chen; Kuan-Hung Lin; Changming Chen; Fengqin Yao; Linshan Zhong; Weiting Chen; Yun-Wei Kuo (Journal of Plant Research, 2022)

Phenomenon of the sediment deposition in a hydraulic jump region of open channels - Wei-lin Xu; Guo-guang Wang; Shi-hao Fu; Wang-ru Wei (Journal of Mountain Science, 2022)

Dapagliflozin protects against doxorubicin-induced cardiotoxicity by restoring STAT3 - Wei-Ting Chang; Jhih-Yuan Shih; Yu-Wen Lin; Zhih-Cherng Chen; Wei-Chih Kan; Tsung-Hsien Lin; Chon-Seng Hong (Archives of Toxicology, 2022)

Streptococcus vulneris sp. nov., isolated from wound of patient with diabetic foot ulcer (DFU) - Jen-hao Chung; Li-Ting Wang; Yi-Sheng Chen; Yun-Shien Lee; Shih-Ting Lin; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Jui-hsiang Li (Archives of Microbiology, 2022)

Genetic Diversity Evaluation and Population Structure Analysis of Red Swamp Crayfish (Procambarus clarkii) from Lakes and Rice Fields by SSR Markers - Xin-Fen Guo; Min Liu; Yu-Lin Zhou; Wen-Yu Wei; Zhi Li; Li Zhou; Zhong-Wei Wang; Jian-Fang Gui (Fishes, 2022)
The red swamp crayfish (Procambarus clarkii) is an important aquatic animal and has developed as a popular aquaculture species in China. In this study, a total of 72,839 SSR motifs were identified from transcriptional data, and 20 microsatellite markers of them were finally developed to assess the genetic diversities of seven wild populations from natural lakes and nine cultured populations from rice fields. Genetic diversity was slightly higher in the cultured populations than in the wild populations. The degree of genetic differentiation between cultured populations is slight, while a moderate to a large degree of genetic differentiation between wild populations and most of the variations occurred within individuals (79%). The analysis of cluster, principal coordinate analysis and STRUCTURE were similar, and they showed that isolation-by-distance pattern was not significant. The microsatellite markers developed in this study can not only be used for genetic monitoring of population but also provide important information for the management of breeding and cultured population in red swamp crayfish.

Near-Optimal Control for Offshore Structures with Nonlinear Energy Sink Mechanisms - Wei Chen; Xingyu Du; Bao-Lin Zhang; Zhihui Cai; Zhongqiang Zheng (Journal of Marine Science and Engineering, 2022)
To improve the safety and reliability of offshore structures subject to wave loading, the active vibration control problem is always one of significant issues in the field of ocean engineering. This paper deals with the near–optimal control problem of offshore structures with a nonlinear energy sink (NES) mechanism. By taking the dominant vibration mode of the offshore structure with the NES into account, a nonlinear dynamic model of the steel–jacket structure subject to wave loading is presented first. Then, using the parameter perturbation approach to solve a nonlinear two–point boundary value problem, an NES–based optimal controller with the form of infinite series sum is presented to suppress the vibration of the offshore structure. Third, an iteration algorithm is provided to obtain the near–optimal controller. Simulation results demonstrate that the NES–based near–optimal controller can mitigate the oscillation amplitude of offshore structures significantly. Moreover, the NES–based optimal controller outperforms the one based on active tuned mass damper.

Decomposition and Nutrient Release into Water from Litter Mixtures of Coastal Wetland Species - Patrick Ndayambaje; Tingfeng Zhang; Lili Wei; Lin Liu; Xu Huang; Jie Li; Shaohua Tian; Yu Xin; Xuecong Sun; Chaoxiang Liu (Wetlands, 2022)

Vegetation dynamics and their response to Holocene climate change derived from multi-proxy records from Wangdongyang peat bog in southeast China - Lin Zhao; Chunmei Ma; Zhenming Wen; Wei Ye; Guangchun Shang; Lingyu Tang (Vegetation History and Archaeobotany, 2022)

Sandstorms cause shrinkage of Haloxylon ammodendron shrubs and limit their self-renewal - Sheng-bo Shi; Dang-wei Zhou; Fang-lin Wang; Rui Shi; Tao Sun; Tian-cai Li; Jia-lin Ma; Xiang Wan; Jian-ping Ma; Jing-nian Tang (Theoretical and Experimental Plant Physiology, 2022)
Haloxylon ammodendron is an excellent windproof and sand-fixing species whose shrubs are widely cultivated in arid desert areas of northwest China but are now at risk of degradation and shrinkage. Using the chlorophyll fluorescence image analysis technique, the response of photosystem II (PSII) photochemical efficiency and non-photochemical quenching capacity to sediment-carrying wind and sand-free wind (both 12 m s −1 ) lasting for 10, 20, and 40 min were studied with seedlings in a wind tunnel. The results indicated that the sand-free wind had little influence on the maximum quantum efficiency of PSII photochemistry, F v / F m , which was approximately 0.80 on average; however, the F v / F m decreased over exposure time in the sediment-carrying wind group, with values smaller than those in the wind-only group. The non-photochemical quenching was sensitive to wind erosion, and sediment-carrying wind could aggravate the reduction in non-photochemical quenching ( NPQ ). Except for the 10 min duration, the maximum quantum efficiency of PSII photochemistry after dark recovery for 15 min, F v r / F m r , was lower in seedlings exposed to sediment-carrying wind than in those in the wind-only group. Compared to wind-only, wind-blown sand led to a water imbalance and withering in seedlings, causing the concentration of photosynthetic pigments (when based on the fresh mass of green branches) to not decrease. With a longer exposure time to sediment-carrying wind, both the probability and extent of lignified spots occurring increased in green assimilative branches. Our results demonstrated that sediment-carrying wind at 12 m s −1 lasting for 20 min or more could cause irreversible damage to the photosynthetic apparatus of H. ammodendron seedlings. Therefore, frequent and strong sandstorms are the main disturbance factors leading to shrinkage of shrubs and limiting their self-renewal.

Identification of the Largest SCA36 Pedigree in Asia: with Multimodel Neuroimaging Evaluation for the First Time - Yue Xie; Zhao Chen; Zhe Long; Rui-Ting Chen; Yi-Zheng Jiang; Ming-Jie Liu; Lin-Liu Peng; Hui-Rong Peng; Na Wan; Guangdong Zou; Chun-Rong Wang; Yu-Ting Shi; et al. (The Cerebellum, 2022)

Transcriptome Changes Induced by Botrytis cinerea Stress and Weighted Gene Co-expression Network Analysis (WGCNA) in Actinidia chinensis - Zhe-Xin Li; Wen-Lin Zhang; Deng-Wei Jue; Xia Liu; Yu-Song Jiang; Jian-Min Tang (Plant Molecular Biology Reporter, 2022)

Genome-wide identification and expression analysis of phospholipase D gene in leaves of sorghum in response to abiotic stresses - Jinpeng Wei; Wenjing Shao; Xinyu Liu; Lin He; Changjiang Zhao; Gaobo Yu; Jingyu Xu (Physiology and Molecular Biology of Plants, 2022)

The Impact of the Antipsychotic Medication Chlorpromazine on Cytotoxicity through Ca2+ Signaling Pathway in Glial Cell Models - Che-Sheng Chu; Yung-Shang Lin; Wei-Zhe Liang (Neurotoxicity Research, 2022)

Correction to: Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines - Hong-Chieh Tsai; Kuo-Chen Wei; Pin-Yuan Chen; Chiung-Yin Huang; Ko-Ting Chen; Ya-Jui Lin; Hsiao-Wei Cheng; Chun-Hao Huang; Hsiang-Tsui Wang (NeuroMolecular Medicine, 2022)

Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines - Hong-Chieh Tsai; Kuo-Chen Wei; Pin-Yuan Chen; Chiung-Yin Huang; Ko-Ting Chen; Ya-Jui Lin; Hsiao-Wei Cheng; Chun-Hao Huang; Hsiang-Tsui Wang (NeuroMolecular Medicine, 2022)

Using DeepLab v3 + -based semantic segmentation to evaluate platelet activation - Tsung-Chen Kuo; Ting-Wei Cheng; Ching-Kai Lin; Ming-Che Chang; Kuang-Yao Cheng; Yun-Chien Cheng (Medical & Biological Engineering & Computing, 2022)

Dynamics of soil organic carbon in different-sized aggregates under splash erosion - Junqiu Lin; Nufang Fang; Yan Zhang; Yi Zeng; Daming Yang; Wei Dai; Ling Wang; Zhihua Shi (Journal of Soils and Sediments, 2022)

Effects of Biogas Slurry on Crop Yield, Physicochemical Properties and Aggregation Characteristics of Lime Concretion Soil in Wheat–Maize Rotation in the North China Plain - Jiao Tang; Anthony J. Davy; Wei Wang; Xihuan Zhang; Dafu Wu; Lin Hu; Jinzhong Yin (Journal of Soil Science and Plant Nutrition, 2022)

TREM-2 mediates dendritic cell–induced NO to suppress Th17 activation and ameliorate chronic kidney diseases - Ching-Cheng Lin; Ti-Yung Chang; Yong-Chen Lu; Yun-Syuan Wu; Wei Huang; Wei-Chi Lo; Guan-Fu Liu; Wei-Chan Hsu; Pamela S. Ohashi; Tak W. Mak; Jong-Ling Fuh; Hui-Chen Chen; et al. (Journal of Molecular Medicine, 2022)

Breast Cancer Awareness Based on Health Information Literacy and Influential Factors among Female Nursing Students in China - Shu Yang; Ping Li; Lin Yu; Na Liu; Jie Wang; Pingping Guo; Xuehui Zhang; Wei Zhang (Journal of Cancer Education, 2022)

Spatiotemporal characteristics and influencing factors of urban resilience efficiency in the Yangtze River Economic Belt, China - Yingzi Lin; Chong Peng; Jianfeng Shu; Wei Zhai; Jianquan Cheng (Environmental Science and Pollution Research, 2022)

Efficient removal of pefloxacin from aqueous solution by acid–alkali modified sludge-based biochar: adsorption kinetics, isotherm, thermodynamics, and mechanism - Hongli Huang; Yongxin Zheng; Dongning Wei; Guang Yang; Xin Peng; Lingjia Fan; Lin Luo; Yaoyu Zhou (Environmental Science and Pollution Research, 2022)

Preliminary study of genome-wide association identifies novel susceptibility genes for serum mineral elements in the Chinese Han population - Duojian Guo; Yu Zhou; Xingwei Wei; Shanshan Zhang; Tianbo Jin; Yutian Zhang; Mei Lin; Xiaoli Zhou; Yufei Xie; Chanyi He; Qi Lin; Ping He; et al. (Biological Trace Element Research, 2022)

Estrogen Deficiency Aggravates Fluoride-Induced Liver Damage and Lipid Metabolism Disorder in Rats - Ya-ming Yu; Bian-hua Zhou; Yi-lin Yang; Cheng-Xiang Guo; Jing Zhao; Hong-wei Wang (Biological Trace Element Research, 2022)

Correction to: R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini - Christine Falcoz; Serge Guzy; Jana Kovač; Isabel Meister; Jean Coulibaly; Somphou Sayasone; David Wesche; Yu-Wei Lin; Jennifer Keiser (Journal of Pharmacokinetics and Pharmacodynamics, 2022)

R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini - Christine Falcoz; Serge Guzy; Jana Kovač; Isabel Meister; Jean Coulibaly; Somphou Sayasone; David Wesche; Yu-Wei Lin; Jennifer Keiser (Journal of Pharmacokinetics and Pharmacodynamics, 2022)

Myd88 knockdown with RNA interference induces in vitro immune hyporesponsiveness in dendritic cells from rhesus monkeys - Qiuhong Wang; Dongyun Cun; Desong Xu; Liang Lin; Jian Jiao; Li Zhang; Cheng Xi; Wei Li; Peng Chen; Mingdao Hu (Immunogenetics, 2022)

Identification of Key Pathways and Genes in SARS-CoV-2 Infecting Human Intestines by Bioinformatics Analysis - Ji-Chun Chen; Tian-Ao Xie; Zhen-Zong Lin; Yi-Qing Li; Yu-Fei Xie; Zhong-Wei Li; Xu-Guang Guo (Biochemical Genetics, 2022)
COVID-19 is a serious infectious disease that has recently swept the world, and research on its causative virus, SARS-CoV-2, remains insufficient. Therefore, this study uses bioinformatics analysis techniques to explore the human digestive tract diseases that may be caused by SARS-CoV-2 infection. The gene expression profile data set, numbered GSE149312, is from the Gene Expression Omnibus (GEO) database and is divided into a 24-h group and a 60-h group. R software is used to analyze and screen out differentially expressed genes (DEGs) and then gene ontology (GO) term and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses are performed. In KEGG, the pathway of non-alcoholic fatty liver disease exists in both the 24-h group and 60-h group. STRING is used to establish a protein–protein interaction (PPI) network, and Cytoscape is then used to visualize the PPI and define the top 12 genes of the node as the hub genes. Through verification, nine statistically significant hub genes are identified: AKT1, TIMP1, NOTCH, CCNA2, RRM2, TTK, BUB1B, KIF20A, and PLK1. In conclusion, the results of this study can provide a certain direction and basis for follow-up studies of SARS-CoV-2 infection of the human digestive tract and provide new insights for the prevention and treatment of diseases caused by SARS-CoV-2.

The optimal combination of Nile red identification, colony polymerase chain reaction, and gas chromatography detection methods in screening for polyhydroxyalkanoicate-producing bacteria - Hung-Che Chou; Chia-Hsin Chen; Hsiao-Kai Chu; Chun-Mei Huang; Hui-Jun Wang; Wei-Lin Tu; Gia-Luen Guo (Archives of Microbiology, 2022)

Medicinal herbs and phytochemicals to combat pathogens in aquaculture - Mengmeng Li; Dongdong Wei; Shuaishuai Huang; Lin Huang; Fengqiao Xu; Qing Yu; Mingzhu Liu; Pengfei Li (Aquaculture International, 2022)

Intelligent identification method and application of seismic faults based on a balanced classification network - Jing Yang; Ren-Wei Ding; Hui-Yong Wang; Nian-Tian Lin; Li-Hong Zhao; Shuo Zhao; Yu-Jie Zhang (Applied Geophysics, 2022)

Natural component plumbagin as a potential antibacterial agent against Streptococcus agalactiae infection - Ai‐Guo Huang; Lin‐Jun Su; Wei‐Hao He; Fa‐Li Zhang; Chao‐Shuai Wei; Ying‐Hui Wang (Journal of Fish Diseases, 2022)
Streptococcus agalactiae , also known as Group B Streptococcus (GBS), can infect humans, terrestrial animals and fish. The emergence of bacterial resistance of S. agalactiae to antibiotics leads to an urgent need of exploration of new antimicrobial agents. In the study, the antibacterial activity of natural component plumbagin (PLB) against S. agalactiae was investigated in vitro and in vivo. The results showed that the minimal inhibitory concentration (MIC) of PLB against S. agalactiae was 8 mg/L. The growth curve assay revealed that PLB could inhibit the growth of S. agalactiae . In addition, the time‐killing curve showed that S. agalactiae was killed almost completely by 2‐fold MIC of PLB within 12 h. Transmission electron microscopy results showed obvious severe morphological destruction and abnormal cells of S. agalactiae after treated with PLB. The pathogenicity of S. agalactiae to zebrafish was significantly decreased after preincubation with PLB for 2 h in vitro, further indicating the bactericidal activity of PLB. Interestingly, PLB could kill S. agalactiae without inducing resistance development. Furthermore, pretreatment and post‐treatment assays suggested that PLB also exhibited the antibacterial activity against S. agalactiae infection in vivo by effectively reducing the bacterial load and improving the survival rate of S. agalactiae ‐infected zebrafish. In summary, PLB had potent antibacterial activity against S. agalactiae in vitro and in vivo, and it could be an excellent antimicrobial candidate to prevent and control S. agalactiae infection.

Optimization of aquaculture sustainability through ecological intensification in China - Shuang‐lin Dong; Yun‐wei Dong; Ling Cao; Johan Verreth; Yngvar Olsen; Wen‐jing Liu; Qi‐zhi Fang; Yan‐gen Zhou; Li Li; Jing‐yu Li; Yong‐tong Mu; Patrick Sorgeloos (Reviews in Aquaculture, 2022)
As the world's leading producer of farmed aquatic food products, China faces great uncertainty concerning the further sustainable development of its aquaculture industry due to high and increasing pressure from environmental and resource constraints. To realize truly sustainable development, it is imperative to establish an evaluation system that integrates social, economic, environmental and resource criteria, and optimizes aquaculture systems through a holistic approach. Here, we used analytical hierarchy processes combined with expert judgment and objective data to assess the sustainability of 10 major aquaculture production systems (APSs) in China. Based on the evaluation results, we propose the ecological intensification of aquaculture systems (ELIAS), rationally integrating anthropogenic inputs with aquaculture ecosystem services, to improve the sustainability of APSs. The holistic evaluation system and ELIAS are fundamental and critical for the future development of aquaculture in China and globally.

Cover Image, Volume 14, Issue 3 - Shuang‐lin Dong; Yun‐wei Dong; Ling Cao; Johan Verreth; Yngvar Olsen; Wen‐jing Liu; Qi‐zhi Fang; Yan‐gen Zhou; Li Li; Jing‐yu Li; Yong‐tong Mu; Patrick Sorgeloos (Reviews in Aquaculture, 2022)
The cover image is based on the Review Article Optimization of aquaculture sustainability through ecological intensification in China by Shuang‐lin Dong et al., https://doi.org/10.1111/raq.12648 image

Potential Application of Biosurfactant-Producing Bacteria for Bioremediation of Oil Polluted Marine Intertidal Sediments - Ping Guo; Wei-Wei Xu; Dan-Na Wei; Man-Xia Zhang; Jin Zhang; Shi Tang; Bin-Xia Cao; Jian-Guo Lin; Wei Li (Journal of Marine Science and Engineering, 2022)
The removal of oil contaminants in marine intertidal sediments under cold climate is an urgent issue. Although the bioavailability of petroleum hydrocarbons decreases at low temperatures, biosurfactants can promote oil biodegradation. In this study, characteristics of biosurfactants produced by cold-adapted oil-degrading bacteria Planococcus sp. XW-1 were studied. Adding the XW-1 biosurfactant could effectively facilitate the solubility of phenanthrene, pyrene, diesel oil, and crude oil. The solubilization was limited by the number of rings and the molecular weight (WSRphenanthrene = 0.0234; WSRpyrene = 0.0165; WSRdiesel oil = 0.0027; WSRcrude oil = 0.0015). Additional biosurfactants significantly washed out crude oil adsorbed to the sand (reduction from 17.1%, 22.7% to 87.9% and 94.28% in 24 h). With the increase in particle size, the removal efficiency increased from 87.9% to 94.28%. After the addition of biosurfactant, the effect of degradation increased by 20% in 20 days. The results suggest that the biosurfactant-producing bacteria Planococcus sp. XW-1 is a promising candidate used in the in situ bioremediation of petroleum-contaminated intertidal sediment.

Tennessenoid A, an Unprecedented Steroid−Sorbicillinoid Adduct From the Marine-Derived Endophyte of Aspergillus sp. Strain 1022LEF - Dong-Lin Zhao; Hai-Su Wang; Li-Wei Gao; Peng Zhang (Frontiers in Marine Science, 2022)
Marine natural products, characterized by fascinating drug-like functionalities and promising biological activities, are important base materials for innovative drugs and agrochemicals. Chemical investigations of the marine-algal-derived endophytic fungus Aspergillus sp. 1022LEF residing in the inner tissue of marine red alga yielded a novel polyketide-terpene hybrid metabolite, namely tennessenoid A ( 1 ), as well as six known biosynthetic congeners including two steroids, ergosta-4,6,8(14),22-tetraen-3-one ( 2 ) and (22 E ,24 R )-3α-ureido-ergosta-4,6,8(14),22-tetraene ( 3 ), and four sorbicillinoid-based compounds, saturnispol G ( 4 ), trichodimerol ( 5 ), and dihydrotrichodimer ethers A and B ( 6 and 7 ). Their structures were unambiguously determined based on extensive 1D/2D NMR and HRESIMS spectroscopic analyses. Tennessenoid A ( 1 ) was characterized as an unprecedented steroid−sorbicillinoid adduct via a C−C bond, which was rarely-observed in natural products. All of the isolated compounds were evaluated for their antifungal activities against eight plant pathogenetic fungi. 1 , in particular, demonstrated broad-spectrum activities against Sclerotium rolfsii Sacc., Fusarium oxysporum (Schl.) F.sp cucumerinum Owen, Coniella diplodiella Petrak et Sydow, Physalospora piricola Nose., Fusarium graminearum schw., Alternaria mali rob., Colletotrichum orbiculare Arx., and Alternaria porri (E11iott) Cifed., with the inhibition zone diameters ranging from 2 to 7 mm.

Differences in the Composition of Abundant Marine Picoeukaryotes in the Marginal Sea Derived from Flooding - Chih-Ching Chung; Gwo-Ching Gong; Yun-Chi Lin; Ching-Wei Hsu (Frontiers in Marine Science, 2022)
The transient impact of flooding on the community composition of marine picoeukaryotes (PEs, cell size ≤5 μm) in the East China Sea (ECS) was revealed in this study. In a summer without flooding (i.e., July 2009), photosynthetic picoeukaryotes (PPEs) were more abundant in the area covered by the Changjiang River diluted water (CDW, salinity ≤31) than in the non-CDW affected area. According to the 18S ribosomal RNA phylogeny, Alveolata (all from the superclass Dinoflagellata) was the main community component accounting for 72 to 99% of the community at each sampling station during the nonflooded summer. In addition to Dinoflagellata, diatoms or Chlorophyta also contributed a considerable proportion to the PE assemblage at the stations close to the edge of CDW coverage. In July 2010, an extreme flooding event occurred in the Changjiang River basin and led to the CDW covering nearly half of the ECS. In the flooded summer, the abundance of PPEs in the CDW-covered area decreased significantly to less than 1 × 10 4 cells ml -1 . Compared to that during the nonflooded summer, the diversity of the PE composition was increased. While Dinophyceae still dominated the surface waters, Syndiniophyceae, which were represented by the uncultured Marine Alveolata Group (MALV)-I and MALV-II, accounted for a substantial amount in the Dinoflagellata superclass relative to this community composition in the nonflooded summer. Furthermore, a variety of plankton, including Cryptophyta, Haptophyta, Picobiliphyta, the uncultured Marine Stramenopiles (MASTs) and heterotrophic nanoflagellates, were observed. The nutrition modes of these PEs have been reported to be mixotrophic or heterotrophic. Therefore, it was inferred that the potentially mixotrophic and heterotrophic PE compositions might be favored in the marginal sea in the flooded summer.

PrPSc Inhibition and Cellular Protection of DBL on a Prion-Infected Cultured Cell via Multiple Pathways - Wei Yang; Cao Chen; Jia Chen; Ying Xia; Chao Hu; Lin Wang; Yue-Zhang Wu; Qi Shi; Zhi-Bao Chen; Xiao-Ping Dong (Molecular Neurobiology, 2022)

Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model - Wan-yi Li; Jun-yan Gao; Su-Yang Lin; Shao-tao Pan; Biao Xiao; Yu-tao Ma; Kai Xie; Wei Shen; Zhi-tao Liu; Guang-yu Li; Jie-jie Guo; Qin-wen Wang; et al. (Molecular Neurobiology, 2022)

Post-failure evolution analysis of an irrigation-induced loess landslide using multiple remote sensing approaches integrated with time-lapse ERT imaging: lessons from Heifangtai, China - Shiqiang Bian; Guan Chen; Runqiang Zeng; Xingmin Meng; Jiacheng Jin; Linxin Lin; Yi Zhang; Wei Shi (Landslides, 2022)

Growth Promotion and Salt-Tolerance Improvement of Gerbera jamesonii by Root Colonization of Piriformospora indica - Weiting Chen; Fazhuang Lin; Kuan-Hung Lin; Changming Chen; Chaoshui Xia; Qiaoling Liao; Shi-Peng Chen; Yun-Wei Kuo (Journal of Plant Growth Regulation, 2022)

A microscopic and quantitative analysis on the separation of chloride ion by fly ash washing: Effect of liquid-to-solid ratio, washing time and temperature - Haogang Huang; Wei Liu; Lin Zhang; Jiamei Fang; Fang Xu; Shi Bu; Weigang Xu; Chen Xu; Hongqi Yao; Zhilei Ma (Environmental Science and Pollution Research, 2022)

Responses of photosynthesis, antioxidant enzymes, and related gene expression to nicosulfuron stress in sweet maize (Zea mays L.) - Zhen-Xing Wu; Ning-Wei Xu; Min Yang; Xiang-Ling Li; Jin-Ling Han; Xiao-Hu Lin; Qing Yang; Gui-Hua Lv; Jian Wang (Environmental Science and Pollution Research, 2022)

Links between continental subduction and generation of Cenozoic potassic–ultrapotassic rocks revealed by olivine oxygen isotopes: A case study from NW Tibet - Gong-Jian Tang; Derek A. Wyman; Qiang Wang; Lin Ma; Wei Dan; Ya-Nan Yang; Xi-Jun Liu; Hong-Yi Chen (Contributions to Mineralogy and Petrology, 2022)

Longer summers in the Northern Hemisphere under global warming - Wei Lin; Chunzai Wang (Climate Dynamics, 2022)

Protective Effect of Selenium-Enriched Green Tea on Carbon Tetrachloride-Induced Liver Fibrosis - Lin Zhang; Jia-Ying Xu; Yanyan Wei; Shi-Lin Gao; Lin Wang; Jia-Yang Zheng; Minghua Gu; Li-Qiang Qin (Biological Trace Element Research, 2022)

Deformation characteristics and thresholds of the Tanjiawan landslide in the Three Gorges Reservoir Area, China - Fu-ling Zhang; Mao-lin Deng; Qing-lin Yi; Shu-qiang Lu; Wei-jun Zheng; Hai-feng Huang; Xing Zhu (Journal of Mountain Science, 2022)

Shinella oryzae sp. nov., a novel zearalenone-resistant bacterium isolated from rice paddy soil - Ruyu Gao; Juan Zheng; Wei Lu; Xiubin Ke; Ming Chen; Min Lin; Wei Zhang; Zhengfu Zhou (Antonie van Leeuwenhoek, 2022)

Unexpected increase of PAH toxicity in ambient particulate matter under the implementation of clean air action: evidence from two megacities in northern China - Weijian Liu; Jinze Wang; Wei Li; Nan Lin; Qingyang Liu; Mengxin Xu; Wei Du (Air Quality, Atmosphere & Health, 2022)

Insight into the dynamic microbial community and core bacteria in composting from different sources by advanced bioinformatics methods - Yabin Zhan; Yuan Chang; Yueyue Tao; Hao Zhang; Yongfeng Lin; Jie Deng; Tiantian Ma; Guochun Ding; Yuquan Wei; Ji Li (Environmental Science and Pollution Research, 2022)

Hypothermal Effects on Energy Supply for Ionocytes in Gills of Freshwater- and Seawater-Acclimated Milkfish, Chanos chanos - Chia-Hao Chang; Chia-Jui Liu; Wei-Jie Lu; Li-Yang Wu; Kuang-Jie Lai; Yu-Ting Lin; Tsung-Han Lee (Frontiers in Marine Science, 2022)
The milkfish, Chanos chanos , is an important aquaculture species that can be cultured in freshwater (FW) and seawater (SW) ponds because of its high euryhalinity. In winter, cold snap leading to high mortality of this tropical species is a critical issue for the aquaculture industry in Taiwan. Under hypothermal stress, however, changes in energy supply for osmoregulation of this euryhaline species is intriguing. In this study, we used an antibody against glycogen phosphorylase (GP) to identify glycogen-rich (GR) cells distributed adjacent to the mitochondria-rich (MR) ionocytes in milkfish gills. Glucose transporter 1 (GLUT1), which plays a major role in energy supply, was also identified and localized in GR cells. Moreover, the expression of indicators of aerobic metabolism and energy production, citrate synthase (CS) and cytochrome c oxidase (COX), were analyzed in gills of FW- and SW-acclimated milkfish to reveal different strategies of energy utilization under hypothermal stress. When exposed to a low-temperature environment, SW individuals used branchial glycogen and lactate to match the energy demands of aerobic metabolism in ionocytes, and elevated aerobic capacity to support and maintain normal functions in gills. However, branchial glycogen mainly localized in the GR cells of FW milkfish was not utilized under hypothermal stress. Meanwhile, a similar level of branchial COX activity and COXIV protein abundance at low temperatures between FW and SW milkfish indicated similar energy requirements in gills. This suggested that another source, but not branchial glycogen, maintained the energy demand in FW milkfish. The present study illustrated differential energy supply strategies in gills between SW- and FW-acclimated milkfish for osmoregulation under low temperatures.

Two new 7,20-epoxy- ent -kaurane diterpenoids from the aerial parts of Isodon serra - Juan-Juan Hu; Bai-Lin Li; Jin-Dan Xie; Hui-Jun Liang; Qian-Ran Li; Jie Yuan; Jie-Wei Wu (Natural Product Research, 2022)

Berberisides A-D: three novel prenylated benzoic acid derivatives and a clerodane glycoside from Berberis tsarica aherndt. - Zhao-Yue Dong; Qing-Hong Zeng; Lin Wei; Xin Guo; Yan Sun; Fan-Cheng Meng; Guo-Wei Wang; Xiao-Zhong Lan; Zhi-Hua Liao; Min Chen (Natural Product Research, 2022)

Overview of yeast environmental stress response pathways and the development of tolerant yeasts - Nai-Xin Lin; Yan Xu; Xiao-Wei Yu (Systems Microbiology and Biomanufacturing, 2022)

Effects of Recovery Ratio on the Fracture Evolution of the Overburden Pressure-Relief Gas Migration Channel for a Fully Mechanized Working Face - Pengxiang Zhao; Jianan Wang; Shugang Li; Hao Li; Lei Qin; Haifei Lin; Chi-Min Shu; Bin Laiwang; Yongyong Jia; Zongyong Wei; Wenbo Pei (Natural Resources Research, 2022)

Geochemistry of rhodonite in the Luziyuan Pb − Zn skarn deposit, Southwestern China - Yulong Yang; Lin Ye; Wei Gao; Tan Bao; Zhenli Li; Yusi Hu; Chen Wei (Mineralogy and Petrology, 2022)

miR-29 family inhibited the proliferation and migration of lung cancer cells by targeting SREBP-1 - Lin Lin; Yongxia Bao; Miao Tian; Qiu Ren; Wei Zhang (Molecular & Cellular Toxicology, 2022)

Effects of Meranzin Hydrate On the LncRNA–miRNA–mRNA Regulatory Network in the Hippocampus of a Rat Model of Depression - Kechao Nie; Lin Liu; Luqi Peng; Mei Zhang; Chunhu Zhang; Bo Xiao; Zian Xia; Wei Huang (Journal of Molecular Neuroscience, 2022)

Biomechanical superiority of locking plate designed with cluster of head screws compared to conventional buttress plate for fixation of posteromedial tibial plateau fractures: A computational assessment - Kai-Cheng Lin; Yih-Wen Tarng; Kun-Jhih Lin; Hung-Wen Wei (Journal of Medical and Biological Engineering, 2022)

Research on the Mechanics Performance of the New Tension–Compression Rock Bolt Through Numerical Simulation - Shuai Yang; Xunguo Zhu; Guofeng Zhang; Lin Yang; Hongchun Xia; Wei Li (Geotechnical and Geological Engineering, 2022)

Alternaria species causing leaf spot on hemp (Cannabis sativa) in Northern China - Hong Cheng; Lin Zhao; Xin Wei; Xi Liu; Guo-Yang Gao; Jian-Xin Deng; Mei-Jia Li (European Journal of Plant Pathology, 2022)

Probiotics and their Metabolites Reduce Oxidative Stress in Middle-Aged Mice - Wen-Yang Lin; Jia-Hung Lin; Yi-Wei Kuo; Pei-Fang Rose Chiang; Hsieh-Hsun Ho (Current Microbiology, 2022)
Aging is an irreversible physiological degradation of living organisms. Accumulated oxidative stress and dysbiosis accelerate aging. Probiotics such as Lactobacillus and Bifidobacterium and their fermented metabolites (postbiotics) have been discovered to exhibit antioxidative activities that regulate oxidative stress and protect cells from oxidative damage. We screened selected Lactobacillus and Bifidobacterium strains and their postbiotics for potential antioxidative activity by using DPPH (2,2-Diphenyl-1-picrylhydrazyl) assay. Strains with their metabolites were selected for mixed formula in experiments involving aging mice. The aged groups presented higher oxidative stress in the brain, liver, heart, and kidney than did young mice. However, treatment with probiotic strains and their postbiotics elevated antioxidative levels, especially in the high-dose probiotics plus postbiotics group. Next-generation sequencing data revealed positive microbiota alterations of Lactobacillus and Bifidobacterium and Akkermansia in the gut. Lactobacillus johnsonii and Akkermansia muciniphila exhibited effective enlargement of relative abundance. Besides, high-dose probiotics and high-dose probiotics plus postbiotics showed significant elevation in serum SCFAs, especially in butyrate. In conclusion, the formula containing Bifidobacterium animalis subsp. infantis BLI-02, Bifidobacterium breve Bv889, Bifidobacterium bifidum VDD088, B. animalis subsp. lactis CP-9, and Lactobacillus plantarum PL-02 and their metabolites may benefit aged people’s health.

Effects of Environmental and Spatial Variables on Bacteria in Zhanjiang Mangrove Sediments - Di-Hua Zhu; Qing-Lang Song; Fang-Hong Nie; Wan Wei; Meng-Meng Chen; Min Zhang; Hong-Ying Lin; Dan-Ju Kang; Zhi-Bao Chen; Anthony G. Hay; Jin-Jun Chen (Current Microbiology, 2022)

Production of sesquiterpene patchoulol in mitochondrion-engineered Saccharomyces cerevisiae - Xin-Yi Tao; Yang-Chen Lin; Feng-Qing Wang; Qing-Hai Liu; Yu-Shu Ma; Min Liu; Dong-Zhi Wei (Biotechnology Letters, 2022)

IgE Reactivity of Potential Allergens from the Swimming Crab Portunus trituberculatus and the Research of ELISA Reagent for Detecting Crab Food Anaphylaxis - Xueni Qiu; Qiongyan Zhou; Xiaoxia Zhu; Wei Lin; Changkao Mu; Ronghua Li; Yangfang Ye; Weiwei Song; Ce Shi; Lei Liu; Huan Wang; Chunlin Wang; et al. (Journal of Ocean University of China, 2022)

Genetic and genomic characterization of multidrug resistant Bacillus subtilis M3 isolated from an activated sludge reactor treating wastewater - Hafeez Ul Haq; Wei Huang; Ye Li; Ting Zhang; Shaocheng Ma; Yajing Zhang; Yongkang Song; Daiyan Lin; Baoyu Tian (Biologia, 2022)

Cloning and expression analysis of hif-1α and downstream genes during hypoxic stress in cobia (Rachycentron canadum) - Jian-sheng Huang; Eric Amenyogbe; Lin-tong Yang; Zhong-liang Wang; Gang Chen; Wei-zheng Wang; Jian-dong Zhang (Aquaculture International, 2022)

Anti-inflammatory constituents from Phyllostachys makinoi Hayata - Chia-Ching Liaw; Yu-Chi Lin; Shao-Yu Wu; Jenny Chun-Ling Kuo; Zhi-Hu Lin; Kai-Wei Lin; Huang Hui-Chi; Li-Ming Yang Kuo; Yao-Haur Kuo (Natural Product Research, 2022)

Water Circulation Driven by Cold Fronts in the Wax Lake Delta (Louisiana, USA) - Qian Zhang; Chunyan Li; Wei Huang; Jun Lin; Matthew Hiatt; Victor H. Rivera-Monroy (Journal of Marine Science and Engineering, 2022)
Atmospheric cold fronts can periodically generate storm surges and affect sediment transport in the Northern Gulf of Mexico (NGOM). In this paper, we evaluate water circulation spatiotemporal patterns induced by six atmospheric cold front events in the Wax Lake Delta (WLD) in coastal Louisiana using the 3-D hydrodynamic model ECOM-si. Model simulations show that channelized and inter-distributary water flow is significantly impacted by cold fronts. Water volume transport throughout the deltaic channel network is not just constrained to the main channels but also occurs laterally across channels accounting for about a quarter of the total flow. Results show that a significant landward flow occurs across the delta prior to the frontal passage, resulting in a positive storm surge on the coast. The along-channel current velocity dominates while cross-channel water transport occurs at the southwest lobe during the post-frontal stage. Depending on local weather conditions, the cold-front-induced flushing event lasts for 1.7 to 7 days and can flush 32–76% of the total water mass out of the system, a greater range of variability than previous reports. The magnitude of water flushed out of the system is not necessarily dependent on the duration of the frontal events. An energy partitioning analysis shows that the relative importance of subtidal energy (10–45% of the total) and tidal energy (20–70%) varies substantially from station to station and is linked to the weather impact. It is important to note that within the WLD region, the weather-induced subtidal energy (46–66% of the total) is much greater than the diurnal tidal energy (13–25% of the total). The wind associated with cold fronts in winter is the main factor controlling water circulation in the WLD and is a major driver in the spatial configuration of the channel network and delta progradation rates.

Failure mechanism and strengthening effect of shield tunnel lining reinforced by steel plates with corbels - Ting-Jin Liu; Si-Wei Chen; Pei-Qin Lin; Hong-Yuan Liu (European Journal of Environmental and Civil Engineering, 2022)

Diversity and Zonation of Benthic Amphipod Crustaceans Affected by the Mississippi Submarine Canyon in the Northern Gulf of Mexico - Yousria S. Soliman; Gilbert T. Rowe; Mary Wicksten; Chih-Lin Wei (Frontiers in Marine Science, 2022)
Amphipod crustacean diversity and zonation are described from the large Mississippi Canyon that extends from the continental shelf across the entire continental margin. Benthic amphipods were sampled on four cruises from 2000 to 2004 from six locations in the Mississippi Canyon from depths of 480 through 2,750 m, and compared with five locations in a second transect on the open continental slope approximately 100 km west of the canyon to assess the canyon effect on the structure and composition of amphipod assemblages. Five replicates were collected from each location using 0.2 m –2 GOMEX box corer. Amphipods amounted to 40% of the total faunal abundance within the canyon compared to only 4% in the non-canyon samples. Of the seventy-two species (19 families) collected, 61 were encountered in the canyon compared to 38 on the non-canyon transect. The trough-like head of the canyon (480 m) supported high densities (4,446–26,933 ind./m 2 ) of the filter feeding, tube dwelling ampeliscid amphipod ( Ampelisca mississippiana ), the highest densities sampled compared to any other single species, at any other location, either within or outside the canyon, reflecting extreme flux of organic detritus from the continental shelf. The dominance by this single species suppressed the within – habitat (alpha) diversity and evenness, compared to relatively high diversity within the 1,000–1,500 m depths interval both in and outside the canyon. The species richness and alpha diversity exhibited mid-depth maxima at ca. 1,100 m both in and out of the canyon. High species richness (61) over the entire length of the canyon is presumed to be a function of greater topographic complexity and intermittent mass wasting of sediment down the canyon axis. The absence of nestedness is attributed to the amphipod reproductive pattern that lacks dispersive larval stages and brooding comparatively small numbers of eggs in this taxon. Despite depressed diversity at the head of the canyon, the fact that the number of amphipod species in the Mississippi Canyon was 1.5 times their numbers on the adjacent slope suggests that this physiographic feature enriches geographic-scale species diversity.

Reasonable application range of flocculation–solidification combined method in treatment of hydraulically dredged mud slurry - Rong-Jun Zhang; Zhi-Hao Xu; Jun-Jie Zheng; Lin-Wei Tu; Zhan-fang Huang (Marine Georesources & Geotechnology, 2022)

Contrasting effects of plant-soil feedbacks on growth and morphology of physically-connected daughter and mother ramets in two clonal plants - Wei Xue; Lin Huang; Wei-Jia Sheng; Jia-Tao Zhu; Shu-Qi Li; Fei-Hai Yu (Plant and Soil, 2022)

Transcriptomic analyses provide insight into adventitious root formation of Euryodendron excelsum H. T. Chang during ex vitro rooting - Yuping Xiong; Shuangyan Chen; Zhenpeng Wei; Xiaohong Chen; Beiyi Guo; Ting Zhang; Yuying Yin; Xincheng Yu; Jinhui Pang; Meiyun Niu; Xinhua Zhang; Yuan Li; et al. (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Assessment of potential sediment disasters and resilience management of mountain roads using environmental indicators - Chao-Yuan Lin; Yuan-Chung Lai; Shao-Wei Wu; Fan-Chung Mo; Cheng-Yu Lin (Natural Hazards, 2022)
In recent years, extreme rainfall events occur frequently, causing serious watershed sediment disasters, destroying mountain roads, and endangering the safety of residents' lives and property. This study aims to deal with the spatial change of potential sediment movement on the road slope pre-disaster and to screen disaster hot spots for early warning and control system. The conceptual model is used to simulate the distribution of primary and/or derived disasters on a watershed scale to assess the impact of sediment disasters caused by heavy rain event. Correlation analysis shows that the models in assessment of primary disaster and derived disaster are significantly correlated with the collapse ratio and disaster ratio, respectively. Since the primary disaster has been considered when calculating the derived disaster risk, the terrain subdivision along Provincial Highway 21 (Tai-21) is extracted to understand the derived sediment disaster on the road slope. The model can effectively evaluate the road sections prone to disasters. According to the risk level, the hot spot of road slope disasters and the management of disaster resilience are determined and can be the reference for disaster prevention and control.

Exosome-Derived lncRNA NEAT1 Exacerbates Sepsis-Associated Encephalopathy by Promoting Ferroptosis Through Regulating miR-9-5p/TFRC and GOT1 Axis - Xue-biao Wei; Wen-qiang Jiang; Ju-hao Zeng; Lin-qiang Huang; Hong-guang Ding; Yuan-wen Jing; Yong-li Han; Yi-chen Li; Sheng-long Chen (Molecular Neurobiology, 2022)
Sepsis can cause sepsis-associated encephalopathy (SAE), but whether SAE was induced or exacerbated by ferroptosis remains unknown. In this study, the rat sepsis model was constructed using the cecal ligation and puncture method. The blood–brain barrier (BBB) permeability was measured by Evans blue dye (EBD) in vivo. The levels of ROS, Fe ion, MDA, GSH, and GPX4 were assessed by enzyme-linked immunosorbent assay (ELISA). The exosomes isolated from serum were cultured with bEnd.3 cells for the in vitro analysis. Moreover, bEnd.3 cells cultured with 100 μM FeCl3 (iron-rich) were to simulate ferroptosis stress. The cell viability was evaluated by Cell Counting Kit-8 (CCK-8) assay. A dual-luciferase reporter gene assay was performed to confirm the relationship between miR-9-5p with NEAT1, TFRC , and GOT1 . In vivo, it is found that BBB permeability was damaged in model rats. Level of ROS, Fe ion, and MDA was increased, and level of GSH and GPX4 was decreased, which means ferroptosis was induced by sepsis. Exosome-packaged NEAT1 in serum was significantly upregulated in model rats. In vitro, it is found that NEAT1 functions as a ceRNA for miR-9-5p to facilitate TFRC and GOT1 expression. Overexpression of NEAT1 enhanced ferroptosis stress in bEnd.3 cells. Increased miR-9-5p alleviated sepsis-induced ferroptosis by suppressing the expression of TFRC and GOT1 both in vivo and in vitro. In conclusion, these findings suggest that sepsis induced high expression of serous exosome-derived NEAT1, and it might exacerbate SAE by promoting ferroptosis through regulating miR-9-5p/ TFRC and GOT1 axis.

Association of genetic polymorphisms of VAX1, MAFB, and NTN1 with nonsyndromic cleft lip with or without cleft palate in Chinese population - Li Peng; Zhenmin Niu; Jiapei Chen; Teng Wan; Dandan Wu; Yusheng Yang; Guomin Wang; Lin Yang; Wei Huang; Zhenqi Chen (Molecular Genetics and Genomics, 2022)

Towards a rapid assessment of highway slope disasters by using multidisciplinary techniques - Meng-Chia Weng; Cheng-Han Lin; Wen-Jie Shiu; Wei-An Chao; Chia-Chi Chiu; Ching-Fang Lee; Wei-Kai Huang; Che-Ming Yang (Landslides, 2022)
Mega-earthquakes and extreme climate events accompanied by intrinsic fragile geology lead to numerous landslides along mountain highways in Taiwan, causing enormous life and economic losses. In this study, a system for rapid slope disaster information integration and assessment is proposed with the aim of providing information on landslide occurrence, failure mechanisms, and subsequent landslide-affected areas to the highway authority rapidly. The functionality of the proposed system is deployed into three units: (1) geohazard rapid report (GeoPORT I), (2) multidisciplinary geological survey report (GeoPORT II), and (3) site-specific landslide simulation report (GeoPORT III). After landslide occurrence, the seismology-based monitoring network rapidly provides the initial slope disaster information, including preliminary location, event magnitude, earthquake activity, and source dynamics, within an hour. Within 3 days of the landslide, a multidisciplinary geological survey is conducted to collect high-precision topographical, geological, and remote-sensing data to determine the possible failure mechanism. After integrating the aforementioned information, a full-scale three-dimensional landslide simulation based on the discrete element method is performed within 10 days to reveal the failure process and to identify the areas potentially affected by subsequent disasters through scenario modeling. Overall, the proposed system can promptly provide comprehensive and objective information to relevant authorities after the event occurrence for hazard assessment. The proposed system was validated using a landslide event in the Central Cross-Island Highway of Taiwan.

Unloading Response Characteristics of Cross Fault Caverns: Effect of Fault Angles - Yong-Hui Shang; Lin-Rong Xu; Yong-Wei Li (Geotechnical and Geological Engineering, 2022)

The effect of preoperative statin treatment on acute kidney injury in elderly patients undergoing valve replacement surgery - Bing-qi Fu; Xue-biao Wei; Zedazhong Su; Ying-wen Lin; Zu-hui Ke; Tong Tan; Ji-yan Chen; Shou-hong Wang; Dan-qing Yu (European Journal of Clinical Pharmacology, 2022)

Simultaneous detection of ten kinds of insecticide residues in honey and pollen using UPLC-MS/MS with graphene and carbon nanotubes as adsorption and purification materials - Xiuyu Pang; Chenyu Li; Chuanjiang Zang; Lei Guan; Peng Zhang; Chunxiang Di; Nan Zou; Beixing Li; Wei Mu; Jin Lin (Environmental Science and Pollution Research, 2022)

Exogenous ascorbic acid application alleviates cadmium toxicity in seedlings of two wheat (Triticum aestivum L.) varieties by reducing cadmium uptake and enhancing antioxidative capacity - Zhen Zhou; Chang Wei; Haitao Liu; Qiujuan Jiao; Gezi Li; Jingjing Zhang; Biao Zhang; Weihuan Jin; Di Lin; Guo Chen; Suqin Yang (Environmental Science and Pollution Research, 2022)

Optimizing the distribution and proportion of various active sites for better NH3-SCR property over Cu/SSZ-13 - Ziqian Liu; Han Jiang; Bin Guan; Yanfei Wei; Xingze Wu; He Lin; Zhen Huang (Environmental Science and Pollution Research, 2022)

Evaluation on explosion characteristics and parameters of pulverized coal for low-quality coal: experimental study and analysis - Hongwei Yan; Baisheng Nie; Chao Peng; Peijun Liu; Xiaotong Wang; Feifei Yin; Jie Gong; Yueying Wei; Shuangshuang Lin; Qiang Gao; Mingwei Cao (Environmental Science and Pollution Research, 2022)

The impact of vertical resolution on the simulation of Typhoon Lekima (2019) by a cloud-permitting model - Mengjuan Liu; Lin Deng; Wei Huang; Wanchen Wu (Frontiers of Earth Science, 2022)

Correction to: Stenotrophomonas nematodicola sp. nov., isolated from Caenorhabditis elegans - Xuyang Wei; Shengwei Lei; Yang Deng; Yuqin Zhang; Lin Zhang; Qiuhong Niu (Archives of Microbiology, 2022)

Experimental study on drill bit torque influenced by artificial specimen mechanical properties and drilling parameters - Changzheng Lu; Wei Yang; Baiquan Lin (Arabian Journal of Geosciences, 2022)

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Effects of Suspended Particles on Exopolysaccharide Secretion of Two Microalgae in Jinjiang Estuary (Fujian, China) - Jie Liu; Xiaoyu Han; Hui Xing; Yiting Nan; Jiahui Lin; Junming He; Sijia Chen; Yanfang Wei; Peiyong Guo (Journal of Marine Science and Engineering, 2022)
The effects of suspended particles (SP) of different concentrations and sizes on the secretion of exopolysaccharide (EPS) by Chlorella pyrenoidosa (C. pyrenoidosa) and Microcystis flos-aquae (M. flos-aquae) in Jinjiang Estuary, Fujian Province, China were studied in co-cultures of microalgae and SP. The results show that the SP concentration has an “inhibit–promote–inhibit” effect on the secretion of EPS by C. pyrenoidosa, whereby there is an optimal concentration of SP corresponding to the largest amount of EPS secreted by C. pyrenoidosa. Low concentrations had no significant effect on the secretion of EPS from M. flos-aquae (p > 0.05), whereas higher concentrations had an inhibitory effect. The C. pyrenoidosa EPS content was found to be significantly decreased in response to SP of small particle sizes (0–75 and 75–120 μm) and significantly increased for SP of large particle sizes (120–150 and 150–500 μm). Small particle sizes (0–75 and 75–120 μm) were found to be beneficial to the secretion of EPS from M. flos-aquae, and the promotion of EPS secretion gradually decreased with the increase in SP particle size. However, when the particle size was too large (120–150 and 150–500 μm), SP had no significant effect on EPS secretion. This study is helpful for understanding the microalgae EPS secretion response to SP and provides a scientific basis for studying the mechanism of EPS secretion by algae and the effect of SP on eutrophication of the estuary.

Anti-proliferative cassane-type diterpenoids from the seeds of Caesalpinia minax - Yunshao Xu; Wei Shi; Lu Feng; Jun Cao; Zheling Feng; Qingwen Zhang; Jinjian Lu; Yang Ye; Ligen Lin (Natural Product Research, 2022)

Global estimation of clear-sky shortwave aerosol direct radiative effects based on CALIPSO observations - Zhenwei Shi; Zhaoxu Zhang; Wei Chen; Yi Lin (International Journal of Remote Sensing, 2022)

Effects of Diversion Wall on the Hydrodynamics and Withdrawal Sediment of A Lateral Intake - Wenlong Zhao; Jian Zhang; Wei He; Lin shi; Xuyun Chen (Water Resources Management, 2022)

Characterization and fine mapping of a lesion mimic mutant (Lm5) with enhanced stripe rust and powdery mildew resistance in bread wheat (Triticum aestivum L.) - Cong Li; Hang Liu; Jian Wang; Qi Pan; Yue Wang; Kunyan Wu; Peiying Jia; Yang Mu; Huaping Tang; Qiang Xu; Qiantao Jiang; Yaxi Liu; et al. (Theoretical and Applied Genetics, 2022)

Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation - Yu-Che Cheng; Chi-Jung Huang; Wei-Chi Ku; Shu-Lin Guo; Lu-Tai Tien; Yih-Jing Lee; Chih-Cheng Chien (Stem Cell Reviews and Reports, 2022)
Little is known about genes that induce stem cells differentiation into astrocytes. We previously described that heat shock protein 27 (HSP27) downregulation is directly related to neural differentiation under chemical induction in placenta-derived multipotent stem cells (PDMCs). Using this neural differentiation cell model, we cross-compared transcriptomic and proteomic data and selected 26 candidate genes with the same expression trends in both omics analyses. Those genes were further compared with a transcriptomic database derived from Alzheimer’s disease (AD). Eighteen out of 26 candidates showed opposite expression trends between our data and the AD database. The mRNA and protein expression levels of those candidates showed downregulation of HSP27, S100 calcium-binding protein A16 (S100A16) and two other genes in our neural differentiation cell model. Silencing these four genes with various combinations showed that co-silencing HSP27 and S100A16 has stronger effects than other combinations for astrocyte differentiation. The induced astrocyte showed typical astrocytic star-shape and developed with ramified, stringy and filamentous processes as well as differentiated endfoot structures. Also, some of them connected with each other and formed continuous network. Immunofluorescence quantification of various neural markers indicated that HSP27 and S100A16 downregulation mainly drive PDMCs differentiation into astrocytes. Immunofluorescence and confocal microscopic images showed the classical star-like shape morphology and co-expression of crucial astrocyte markers in induced astrocytes, while electrophysiology and Ca 2+ influx examination further confirmed their functional characteristics. In conclusion, co-silencing of S100A16 and HSP27 without chemical induction leads to PDMCs differentiation into functional astrocytes. Graphical abstract

Mucormycosis in Mainland China: A Systematic Review of Case Reports - Lin-Wei Wei; Pei-Qiu Zhu; Xiao-Qing Chen; Jin Yu (Mycopathologia, 2022)

Phactr1 negatively regulates bone mass by inhibiting osteogenesis and promoting adipogenesis of BMSCs via RhoA/ROCK2 - Wei Lin; Zhipeng Chen; Xiaoyi Mo; Shengli Zhao; Zhenxing Wen; Wing Hoi Cheung; Dan Fu; Bailing Chen (Journal of Molecular Histology, 2022)

Evaluation of reference genes for normalization of mRNA and microRNA expression by RT-qPCR under different experimental conditions in Medicago ruthenica (L.) Ledeb. - Mao-Wei Guo; Lin Zhu; Hong-Yan Li; Zi-Nian Wu; Zhi-Yong Li; Jun Li (Genetic Resources and Crop Evolution, 2022)

ARRDC3 polymorphisms may affect the risk of glioma in Chinese Han - Nan Li; Hangyu Shi; Pengfei Hou; Lu Gao; Yongqiang Shi; Weiyang Mi; Gang Zhang; Ning Wang; Wei Dai; Lin Wei; Tianbo Jin; Yongzhi Shi; et al. (Functional & Integrative Genomics, 2022)

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss) - Hui-Xia Yu; Yang Li; Wei-Jia Song; Hui Wang; Hao-Lin Mo; Qiao Liu; Xin-Miao Zhang; Ze-Bin Jiang; Li-Xin Wang (Fish Physiology and Biochemistry, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Feasibility and usability of a mobile health tool on anticoagulation management for patients with atrial fibrillation: a pilot study - Chi Zhang; Mang-Mang Pan; Na Wang; Wei-Wei Wang; Zheng Li; Zhi-Chun Gu; Hou-Wen Lin (European Journal of Clinical Pharmacology, 2022)

Research on cropping intensity mapping of the Huai River Basin (China) based on multi-source remote sensing data fusion - Yihang Wang; Lin Fan; Ranting Tao; Letao Zhang; Wei Zhao (Environmental Science and Pollution Research, 2022)

Airborne black carbon variations during the COVID-19 lockdown in the Yangtze River Delta megacities suggest actions to curb global warming - Hao Li; Kan Huang; Qingyan Fu; Yanfen Lin; Jia Chen; Congrui Deng; Xudong Tian; Qian Tang; Qingchuan Song; Zhen Wei (Environmental Chemistry Letters, 2022)

Higher sequestration of wheat versus maize crop carbon in soils under rotations - Zheng-Rong Kan; Shou-Wei Han; Wen-Xuan Liu; Xin Zhao; Rattan Lal; Hai-Lin Zhang (Environmental Chemistry Letters, 2022)

Induction and Genomic Analysis of a Lysogenic Phage of Hafnia paralvei - Lingting Pan; Dengfeng Li; Yigang Tong; Wei Lin; Weinan Qin; Lihua Xu; Pingping Zhan (Current Microbiology, 2022)

Overall and central obesity and prostate cancer risk in African men - Ilir Agalliu; Wei-Kaung Jerry Lin; Janice S. Zhang; Judith S. Jacobson; Thomas E. Rohan; Ben Adusei; Nana Yaa F. Snyper; Caroline Andrews; Elkhansa Sidahmed; James E. Mensah; Richard Biritwum; Andrew A. Adjei; et al. (Cancer Causes & Control, 2022)

Transcriptome Analysis Reveals Molecular Mechanisms Underlying Methyl Jasmonate-mediated Biosynthesis of Protopanaxadiol-type Saponins in Panax notoginseng Leaves - Ying Li; Yuan Lin; Bing Jia; Geng Chen; Huineng Shi; Rui Xu; Xuejiao Li; Junrong Tang; Qingyan Tang; Guanghui Zhang; Jianli Yang; Wei Fan; et al. (Journal of Plant Biology, 2022)

A Preliminary Study on Silver Isotopic Composition in Polymetallic Ore Deposits in Eastern China - Ge Dong; Hai-Zhen Wei; Yuanfeng Zhu; Xi Liu; Qi Guo; Wei Pu; Yibo Lin; Junlin Wang (Journal of Earth Science, 2022)

Reference Module-Based Analysis of Ovarian Cancer Transcriptome Identifies Important Modules and Potential Drugs - Xuedan Lai; Peihong Lin; Jianwen Ye; Wei Liu; Shiqiang Lin; Zhou Lin (Biochemical Genetics, 2022)

Large‐scale circulation features responsible for different types of extreme high temperatures with extreme coverage over South China - Wenting Lin; Ruidan Chen; Zhiping Wen; Wei Chen (International Journal of Climatology, 2022)
This study classifies the summer extreme high temperatures (EHT) over South China into Day‐EHT, Night‐EHT and Mixed‐EHT (corresponding to EHT with extreme coverage only in daytime, only at night and both in daytime and at night) and compares their associated circulation patterns. All types of EHT are associated with the intensification and expansion of western Pacific subtropical high (WPSH). Concurrently, anomalous subsidence occurs over South China, which reduces the cloud cover and favours daytime warming. However, different types of EHT feature different circulation configurations. Day‐EHT are influenced by the northwestward‐extending WPSH and tropical cyclones, manifesting an abnormal anticyclonic‐cyclonic pair. Anomalous northeasterly winds dominate over South China, which cause lower humidity and faster heat dissipation and thus the EHT disappear at night. Night‐EHT are related to the westward‐extending WPSH and intensified East Asian westerly trough, presenting a subtropical anticyclonic anomaly and a mid‐latitude cyclonic anomaly. Anomalous southwesterly and northerly flows meet around South China, favouring more water vapour convergence in situ. The above‐normal humidity results in smaller amplitude of cloud cover reduction and weaker daytime warming compared to Day‐EHT, but favours heat maintenance and Night‐EHT. Moreover, the mid‐high‐latitude wave train preceding Day‐EHT (Night‐EHT) lies more northward (southward) with the upstream high‐pressure anomaly occurring around the Ural Mountains (Caspian Sea). Mixed‐EHT combine the anomalies for Day‐EHT and Night‐EHT and weak humidity anomaly occurs over South China, thus the daytime EHT could persist until night albeit cools down slightly. These distinguished features indicate that different types of EHT should be considered separately for better forecast and projection of EHT.

Chemical constituents from the fruits of Piper longum L. and their vascular relaxation effect on rat mesenteric arteries - Dan Li; Rui Wang; Xiaohan Cheng; Jianfeng Yang; Yihui Yang; Huichong Qu; Sen Li; Shan Lin; Donghua Wei; Yuhua Bai; Xiaodong Zheng (Natural Product Research, 2022)

Dimeric hexylitaconic acids from the marine-derived fungus Aspergillus welwitschiae CUGBMF180262 - Jiahui Han; Na Yang; Shangzhu Wei; Jia Jia; Rui Lin; Jiangpeng Li; Hongkai Bi; Fuhang Song; Xiuli Xu (Natural Product Research, 2022)

Distribution of Coomassie Blue Stainable Particles in the Pearl River Estuary, China, Insight Into the Nitrogen Cycling in Estuarine System - Cui-Ci Sun; Wei-Zhong Yue; You-Shao Wang; Wei-Hong He; Yi-Guo Hong; Fu-Lin Sun; Hao Cheng; Mei-Lin Wu; Zhao-Yu Jiang; Fei Jiao; Yu-Tu Wang (Frontiers in Marine Science, 2022)
Distributions of Coomassie Blue stainable particles (CSP), the sources and transports, as well as their implications for nitrogen biogeochemical cycles in the Pearl River estuary (PRE) were investigated during two cruises in August 2016 and January 2017. CSP color concentrations (CSP concentration determined spectrophotometrically) were 73.7–685.3 μg BSA eq L –1 [μg Bovine serum albumin (BSA) equivalent liter –1 ] in August 2016 and 100.6–396.4 μg BSA eq L –1 in January 2017, respectively. CSP concentrations were high in low-salinity waters (<5), and declined from the river to the middle estuary by 80% in the wet season and 55.6% in the dry season, respectively, then increased again in the lower estuary due to high primary production. CSP concentrations were mainly associated with chlorophyll a (Chl a ) concentration except for the turbid mixing zone, suggesting that autochthonous phytoplankton production served as the primary source of CSP in the PRE. The concentrations of nitrogen (N) as CSP in the PRE were comparable to the nitrogen content of particulate hydrolysable amino acids (PHAA). Pictures of CSP taken by microscopy and the correlation between composition of PHAA and the ratio of Chl a /CSP color showed that CSP were relatively degraded due to delivery of old terrestrial protein to river section and extensive microbial degradation during mixing at the upper and middle parts of the estuary, whereas CSP in lower estuary appeared to be more labile due to higher fresh algal production. The contribution of CSP nitrogen (CSP-N) to the particulate nitrogen (PN) pool was 34.98% in summer and 30.8% in winter. The conservative estimate of CSP-N input flux in the Pearl River Delta was about 6 × 10 6 mol N d –1 . These results suggested that CSP was a significant pool of organic nitrogen in the PRE. The study of CSP composition in terms of nitrogen provides new insight into the roles of CSP on nitrogen biogeochemical processes in the turbid and productive estuarine system.

Biomimetic synthesis of 6-substituted dihydrobenzophenanthridine alkaloids based on visible-light promoted radical addition reaction - Pi Cheng; Wei Wang; Xinhao Wang; Lin Wang; Wei Liu; Jianguo Zeng (Natural Product Research, 2022)

8- O - β -D-Glucopyranosyl-2-methylchromone, a new chromone glycoside from the Tibetan medicine plant of Swertia punicea Hemsl - Lin-Yun Mou; Min Wei; Hai-Yan Wu; Li-Jiao Hu; Jian-Long Li; Gan-Peng Li (Natural Product Research, 2022)

Biochanin A as an α-hemolysin inhibitor for combating methicillin-resistant Staphylococcus aureus infection - Jiaxuan Feng; Dazhong Sun; Li Wang; Xueting Li; Jiyu Guan; Lin Wei; Donghui Yue; Xingye Wang; Yicheng Zhao; Haimiao Yang; Wu Song; Bingmei Wang (World Journal of Microbiology and Biotechnology, 2022)

Effects of ultra-long fermentation time on the microbial community and flavor components of light-flavor Xiaoqu Baijiu based on fermentation tanks - Jie Tang; Yuancai Liu; Bin Lin; Hao Zhu; Wei Jiang; Qiang Yang; Shenxi Chen (World Journal of Microbiology and Biotechnology, 2022)

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Lactoferrin promotes the autophagy activity during osteoblast formation via BCL2-Beclin1 signaling - Dianshan Ke; Xinwen Wang; Yinquan Lin; Shengwang Wei (Molecular Biology Reports, 2022)

An innovative targeted therapy for fluoroscopy-induced chronic radiation dermatitis - Kai-Che Wei; Shih-Fan Lai; Wei-Lun Huang; Kuo-Chung Yang; Ping-Chin Lai; Wan-Ju Wei; Tsung-Hsien Chang; Yun-Chen Huang; Ya-Chuan Tsai; Shin-Chih Lin; Sun-Jang Lin; Shih-Chieh Lin (Journal of Molecular Medicine, 2022)
Fluoroscopy-induced chronic radiation dermatitis (FICRD) is a complication of fluoroscopy-guided intervention. Unlike acute radiation dermatitis, FICRD is different as delayed onset and usually appears without preexisting acute dermatitis. Unfortunately, the chronic and progressive pathology of FICRD makes it difficult to treat, and some patients need to receive wide excision and reconstruction surgery. Due to lack of standard treatment, investigating underlying mechanism is needed in order to develop an effective therapy. Herein, the Hippo pathway is specifically identified using an RNA-seq analysis in mild damaged skin specimens of patients with FICRD. Furthermore, specific increase of the Yes-associated protein (YAP1), an effector of the Hippo pathway, in skin region with mild damage plays a protective role for keratinocytes via positively regulating the numerous downstream genes involved in different biological processes. Interestingly, irradiated-keratinocytes inhibit activation of fibroblasts under TGF-β1 treatment via remote control by an exosome containing YAP1. More importantly, targeting one of YAP1 downstream genes, nuclear receptor subfamily 3 group C member 1 (NR3C1), which encodes glucocorticoid receptor, has revealed its therapeutic potential to treat FICRD by inhibiting fibroblasts activation in vitro and preventing formation of radiation ulcers in a mouse model and in patients with FICRD. Taken together, this translational research demonstrates the critical role of YAP1 in FICRD and identification of a feasible, effective therapy for patients with FICRD. Key messages • YAP1 overexpression in skin specimens of radiation dermatitis from FICRD patient. • Radiation-induced YAP1 expression plays protective roles by promoting DNA damage repair and inhibiting fibrosis via remote control of exosomal YAP1. • YAP1 positively regulates NR3C1 which encodes glucocorticoid receptor expression. • Targeting glucocorticoid receptor by prednisolone has therapeutic potential for FICRD patient.

Zeb2/Axin2-Enriched BMSC-Derived Exosomes Promote Post-Stroke Functional Recovery by Enhancing Neurogenesis and Neural Plasticity - Rui Wei; Lin Zhang; Wei Hu; Xinying Shang; Yuyan He; Wei Zhang (Journal of Molecular Neuroscience, 2022)

Verification of Real-Time Microbial Monitoring Technology Based on the Principle of Laser-Induced Fluorescence Under USP <1223> Standard and Prospective Application in Our Hospital PIVAS Clean Room - Zhou Geng; Wenbin Yang; Shubo Wei; Lin Wang; Jie Pan (International Journal of Peptide Research and Therapeutics, 2022)

PHD2 attenuates high-glucose-induced blood retinal barrier breakdown in human retinal microvascular endothelial cells by regulating the Hif-1α/VEGF pathway - Jia Li; Xi Lu; Liqing Wei; Dan Ye; Jianqiang Lin; Xiaoyu Tang; Kaixuan Cui; Shanshan Yu; Yue Xu; Xiaoling Liang (Inflammation Research, 2022)

Study on In-seam Wave Response Characteristics of Reflection in Fault Bearing Coal Seam of Shuangliu Coal Mine - Lei Zhang; Lin Xu; Zhulin Wei; Congcong Feng (Geotechnical and Geological Engineering, 2022)

Regulatory role of miR-129 and miR-384-5p on apoptosis induced by oxygen and glucose deprivation in PC12 cell - Hui-Lin Guan; Yue Guan; Wen-Yuan Li; Jia-Wei Liu; Yu-Jia Zheng; Yan-Zhong Guan; Hong-Feng Liu; Li-Xin Guan; Feng-Guo Zhai (Experimental Brain Research, 2022)

Evolutionary game analysis of coal enterprise resource integration under government regulation - Ziyuan Sun; Wei Wang; Weixing Zhu; Lin Ma; Yuting Dong; Jiangwei Lu (Environmental Science and Pollution Research, 2022)

Emission inventory and control policy for non-road construction machinery in Tianjin - Qijun Zhang; Ning Wei; Lei Yang; Xi Feng; Yanjie Zhang; Lin Wu; Hongjun Mao (Environmental Science and Pollution Research, 2022)

Performance and mechanisms of fly ash for graphene oxide removal from aqueous solution - Ping Jiang; Lin Zhou; Wei Wang; Na Li; Fang Zhang (Environmental Science and Pollution Research, 2022)

Watershed runoff modeling through a multi-time scale approach by multivariate empirical mode decomposition (MEMD) - Hanyu Zhang; Lin Liu; Wei Jiao; Kai Li; Lizhi Wang; Qianjin Liu (Environmental Science and Pollution Research, 2022)

Pharmaceuticals in drinking water sources and tap water in a city in the middle reaches of the Yangtze River: occurrence, spatiotemporal distribution, and risk assessment - Peng He; Junmei Wu; Jingqian Peng; Lin Wei; Liping Zhang; Qiaohong Zhou; Zhenbin Wu (Environmental Science and Pollution Research, 2022)

Pilot study on the treatment of low carbon and nitrogen ratio municipal sewage by A1/O2/A3/A4/O5 sludge-membrane coupling process with multi-point inflow - De-Wei Zhang; Jun-Tian Zheng; Jun Zheng; Meng-Ke Zhao; Meng-Lin Wang; Shi-Hua Zhang (Environmental Science and Pollution Research, 2022)

Molecular Mechanism of Aluminum-Induced Oxidative Damage and Apoptosis in Rat Cardiomyocytes - LiuFang Zhou; Mingjie He; XiaoLan Li; Erbing Lin; YingChuan Wang; Hua Wei; Xi Wei (Biological Trace Element Research, 2022)

Improved forward and backward adaptive smoothing algorithm - Xu Lin; Xinghai Yang; Chihao Hu; Wei Li (GPS Solutions, 2022)

Alcanivorax limicola sp. nov., isolated from a soda alkali-saline soil - Lin Zhu; Yuan Wang; Yiwei Ding; Kai Luo; Biyue Yang; Sai Yang; Shenkui Liu; Henglin Cui; Wei Wei (Archives of Microbiology, 2022)

Sabulicella rubraurantiaca gen. nov., sp. nov., a new member of the family Acetobacteraceae, isolated from desert soil - Zhi-Liang Lin; Shuai Li; Qi-Chuang Wei; Wen-Hui Lian; Chun-Yan Lu; Lu Xu; Li-Nan Huang; Lei Dong; Wen-Jun Li (Archives of Microbiology, 2022)