Integrative analysis uncovers response mechanism of Pirata subpiraticus to chronic cadmium stress - Ou-lin Dai; Zi-yan Lei; Yuan-de Peng; Zhi Wang (Environmental Science and Pollution Research, 2022)

Identifying trends and driving factors of spatio-temporal water quality variation in Guanting Reservoir Basin, North China - Jingqiu Jiang; Gaofeng Zhao; Dewang Wang; Lin Liu; Xu Yan; Huarong Song (Environmental Science and Pollution Research, 2022)

Failure mode and genesis of bare dispersive soil slope in the cold dry region: insights from Southwest Songnen Plain, China - Yan Han; Qing Wang; Cencen Niu; Huicheng Fu; Jing Liu; Mengxia Han; Sen Lin; Muhammad Ammar (Bulletin of Engineering Geology and the Environment, 2022)

Trace Element Changes in the Plasma of Autism Spectrum Disorder Children and the Positive Correlation Between Chromium and Vanadium - Jun Zhang; Jing Lin; Xiying Zhao; Fang Yao; Chengyun Feng; Zhijun He; Xueshan Cao; Yan Gao; Naseer Ullah Khan; Margy Chen; Peng Luo; Liming Shen (Biological Trace Element Research, 2022)

BCL11B Upregulates the Expression of RelA in T Cells Stimulated with Staphylococcal Enterotoxin A - Y. Yan; S. Wang; C. Lin (Bulletin of Experimental Biology and Medicine, 2022)

CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8 - Xiaoqin Li; Xuemei Jiang; Jing Lu; Yuting Lin; Lan Jiang; Yan Li; Feng Wan; Changmin Wang (Biochemical Genetics, 2022)

RMP-Net: A structural reparameterization and subpixel super-resolution-based marine scene segmentation network - Jiongjiang Chen; Jialin Tang; Shounan Lin; Wanxin Liang; Binghua Su; Jinghui Yan; Dujuan Zhou; Lili Wang; Yunting Lai; Benxi Yang (Frontiers in Marine Science, 2022)
Ocean exploration has always been an important strategic direction for the joint efforts of all mankind. Many countries in the world today are developing their own underwater autonomous explorers to better explore the seabed. Vision, as the core technology of autonomous underwater explorers, has a great impact on the efficiency of exploration. Different from traditional tasks, the lack of ambient light on the seabed makes the visual system more demanding. In addition, the complex terrain on the seabed and various creatures with different shapes and colors also make exploration tasks more difficult. In order to effectively solve the above problems, we combined the traditional models to modify the structure and proposed an algorithm for the super-resolution fusion of enhanced extraction features to perform semantic segmentation of seabed scenes. By using a structurally reparameterized backbone network to better extract target features in complex environments, and using subpixel super-resolution to combine multiscale feature semantic information, we can achieve superior ocean scene segmentation performance. In this study, multiclass segmentation and two-class segmentation tests were performed on the public datasets SUIM and DeepFish, respectively. The test results show that the mIoU and mPA indicators of our proposed method on SUIM reach 84.52% and 92.33%mPA, respectively. The mIoU and mPA on DeepFish reach 95.26% and 97.38%, respectively, and the proposed model achieves SOTA compared with state-of-the-art methods. The proposed model and code are exposed via Github 1 .

Numerical Investigation of Depressurization through Horizontal Wells in Methane-Hydrate-Bearing Sediments Considering Sand Production - Xuyang Guo; Yan Jin; Jingyu Zi; Jiaying Lin; Bolong Zhu; Qian Wen; Qi Jing (Journal of Marine Science and Engineering, 2022)
Sand production has been identified as a key reason limiting sustained and commercial gas production in methane-hydrate-bearing sediments. Production tests in Canada and Japan were terminated partially because of excessive sand production in pilot wells. It is meaningful to carry out numerical investigations and sensitivity analyses to improve the understanding of sand production mechanisms during the exploitation of methane hydrates. This study introduces a numerical model to describe the coupled thermal–hydraulic–mechanical–chemical responses and sand production patterns during horizontal well depressurization in methane-hydrate-bearing sediments. The model is benchmarked with a variety of methane hydrate reservoir simulators. Results show that the spatial and temporal evolution patterns of multi-physical fields are different and the hydromechanical evolutions are the fastest. Gas production and sand production rates are oscillatory in the early stages and long-term rates become stable. Gas production is sensitive to rock physical and operational parameters and insensitive to rock mechanical properties such as cohesion. In contrast, sand production is sensitive to cohesion and insensitive to rock physical and operational parameters. Although cohesion does not directly affect gas productivity, gas productivity can be impaired if excessive sand production impedes production operations. This study provides insights into the sand production mechanism and quantifies how relevant parameters affect sand production during the depressurization in methane-hydrate-bearing sediments.

Holocene sedimentary of the Pearl River Delta in South China: OSL and radiocarbon dating of cores from Zhuhai - Penghui Lin; Xiaolin Xu; Chaoyang Yan; Lan Luo; Mahmoud Abbas; Zhongping Lai (Frontiers in Marine Science, 2022)
Deltaic sediments provide a window for investigating delta development processes and the effects of human activities. Despite the fact that numerous studies have been conducted in the Pearl River Delta (PRD), the chronological data are still very limited, which hinder the detailed interpretation of the sedimentary records. The current study aims to establish high-resolution chronology on two cores from Zhuhai using quartz optically stimulated luminescence (OSL) and radiocarbon ( 14 C) dating and, further, to reconstruct the Holocene sedimentary history of the PRD. Core P1-1 has a depth of 79 m and core P3-2 a depth of 60 m. Thirteen quartz OSL samples from P1-1 produced ages between 10.4 and 0.16 ka. Eight OSL and eight 14 C ages from P3-2 span from 10.7 to 0.3 ka. The OSL and 14 C dates show a good agreement above the depth of 26 m (1.4–0.3 ka), but with discrepancies at depths of 26–54 m. 14 C ages (10.7–8.1 ka) are generally older (up to c. 2 ka) than quartz OSL ages, and the discrepancy decreases with depth. The age model shows three phases of the sedimentation process: (1) rapid accumulation rates of 7.48 (P1-1) and 7.52 (P3-2) m/ka between c. 10.7 and 7.5 ka in response to high sea level, (2) followed by a significantly reduced rate of 2.24 m/ka (P1-1) and a depositional hiatus (P3-2) from 7.5 to 2.5 ka as a result of reduced sediment supply and strong scouring by tidal processes, and (3) high sedimentation rates of 8.86 (P1-1) and 9.07 (P3-2) m/ka since 2.5 ka associated with intensive human activities and weakening tidal hydrodynamics. This sedimentary pattern is also evident in many other Asian deltas.

Forecasts of MJO during DYNAMO in a coupled tropical channel model, Part I: Impact of parameterization schemes - Yun Hu; Xiaochun Wang; Jing‐Jia Luo; Dongxiao Wang; Huiping Yan; Chaoxia Yuan; Xia Lin (International Journal of Climatology, 2022)
A coupled tropical channel model is developed to forecast the Madden–Julian Oscillation (MJO) event during the Dynamics of the MJO (DYNAMO) campaign period. Eight sets of 30‐day hindcast experiments are performed using different combinations of cumulus parameterization and planetary boundary layer (PBL) schemes. The results indicate that a well‐simulated mean state is a prerequisite for MJO forecast, and the model's ability to reproduce the mean state is sensitive to the parameterization schemes. The experiment with Tiedtke (TDK) cumulus parameterization and University of Washington (UW) PBL schemes can successfully predict the MJO event. Over the equatorial Indian Ocean, this experiment has a good representation of zonal sea surface temperature (SST) gradient and low‐level westerly wind, favouring a reasonable atmospheric circulation. As a result of boundary‐layer convergence in the eastern Indian Ocean, more water vapour is gathered in the low‐middle troposphere by updrafts, contributing to the PBL moistening ahead of the MJO convection and the eastward‐propagation of MJO precipitation. Further analysis reveals that the high cloud is accompanied by strong convection. A better simulation in tropical high cloud fraction helps trap the cloud radiation heating to warm middle‐upper troposphere, which promotes the MJO propagation. Our results suggest that the selection of proper parameterization schemes with a better‐simulated mean state is crucial to predicting the MJO event in the tropical channel model.

Prolonged electrolysis injures the neural development of zebrafish (Danio rerio) - Chaoqun Zheng; Yan Gao; Jinling Zhu; Lin Gan; Mengmeng Wang; Wen Zhang; Shunqing Yang; Liuyan Yang (Environmental Science and Pollution Research, 2022)

Two new sesquiterpenoid lactone derivatives from Lindera aggregata - Song-Song Wen; Yan Wang; Jia-Ping Xu; Qi Liu; Lei Zhang; Jing Zheng; Lin Li; Na Zhang; Xin Liu; Yu-Wen Xu; Zhen-Liang Sun (Natural Product Research, 2022)

Rose Bengal inhibits β-amyloid oligomers-induced tau hyperphosphorylation via acting on Akt and CDK5 kinases - Chen-Ye Mou; Yan-Fei Xie; Jia-Xin Wei; Qi-Yao Wang; Jing-Yang Le; Yong-Jie Bao; Pan-Pan Zhang; Yue-Chun Mao; Xing-Han Huang; Han-Bo Pan; C. Benjamin Naman; Lin Liu; et al. (Psychopharmacology, 2022)

ACC deaminase-encoding Pseudomonas putida arrests seed germination: an alternative strategy for grass and weed control - Di Zhou; Jia-Ling Zhao; Rui Wang; Hai-Lin Wang; Daniela D. Herrera-Balandrano; Tang-Min Chen; Xiao-Feng Lu; Xu-Chu Duan; Mahdi Shahriar; Xin-Chi Shi; Pedro Laborda; Su-Yan Wang (Plant and Soil, 2022)

Development of diagnostic molecular markers to differentiate sharp eyespot and Fusarium crown rot isolates collected from common wheat fields in China - Yan Ren; Yue Wang; Li-yan Wang; Xia-Lei Lv; Ti Liu; Jing-yun Nie; Peng Guo; Lin Ma; Xiao-nan Sun; Feng Chen (Phytoparasitica, 2022)

Unique Pharmacology, Brain Dysfunction, and Therapeutic Advancements for Fentanyl Misuse and Abuse - Ying Han; Lu Cao; Kai Yuan; Jie Shi; Wei Yan; Lin Lu (Neuroscience Bulletin, 2022)

GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level - Zhi-Rong Lin; Zhen-Zhen Li; Yan-Jun Cao; Wen-Jing Yu; Jian-Tao Ye; Pei-Qing Liu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2022)

Correction to: circ-CCND1 regulates the CCND1/P53/P21 pathway through sponging miR-138-5p in valve interstitial cells to aggravate aortic valve calcification - Fei Yan; Xiang Xie; Qiang Huo; Weimin Zhang; Tingting Wu; Daniyaer Dilimulati; Lin Shi (Journal of Physiology and Biochemistry, 2022)

circ-CCND1 regulates the CCND1/P53/P21 pathway through sponging miR-138-5p in valve interstitial cells to aggravate aortic valve calcification - Fei Yan; Xiang Xie; Qiang Huo; Weimin Zhang; Tingting Wu; Daniyaer·Dilimulati; Lin Shi (Journal of Physiology and Biochemistry, 2022)

Effect of simulated earthquake loading on radon exhalation from uranium tailings dam - Yan Chen; Changshou Hong; Xiangyang Li; Yong Liu; Yifan Chen; Xingwang Dai; Hong Wang; Dongying Lin (Environmental Science and Pollution Research, 2022)

Construction and evaluation of curcumin upconversion nanocarriers decorated with MnO2 for tumor photodynamic therapy - Xinru Chen; Quandong Li; Zipeng Huang; Wen Lin; Yan Ma (Drug Delivery and Translational Research, 2022)

Effects of Biocontrol Agents Application on Soil Bacterial Community and the Quality of Tobacco - Zhongkui Li; Yulan Chen; Aifen Ling; Hongli Li; Zhengquan Lin; Yan Wang (Current Microbiology, 2022)

Effect of gravel content on the detachment of colluvial deposits in Benggang - Li-ting Zhang; Fang Shuai; Li-bo Chen; Yan-he Huang; Jin-shi Lin; Yue Zhang; Hong-li Ge; Fang-shi Jiang (Journal of Mountain Science, 2022)

Complete genome sequence of iris potyvirus B infecting Lilium lancifolium in China - Qi Lin; Dankan Yan; Mengying Hua; Yueyan Yin; Hongying Zheng; Jianping Chen; Fei Yan; Jiejun Peng; Qiongji He; Yuwen Lu (Archives of Virology, 2022)

Sphingomicrobium nitratireducens sp. nov., isolated from a tidal flat in Guangxi - Hao You; Lin Xu; Yan-Hui Kong; Cong Sun; Peng Zhou; Xue-Wei Xu (Archives of Microbiology, 2022)

Anti-drug Antibody Sample Testing and Reporting Harmonization - Darshana Jani; Robin Marsden; Michele Gunsior; Laura Schild Hay; Bethany Ward; Kyra J. Cowan; Mitra Azadeh; Breann Barker; Liching Cao; Kristin R. Closson; Kelly Coble; Sanjay L. Dholakiya; et al. (The AAPS Journal, 2022)
A clear scientific and operational need exists for harmonized bioanalytical immunogenicity study reporting to facilitate communication of immunogenicity findings and expedient review by industry and health authorities. To address these key bioanalytical reporting gaps and provide a report structure for documenting immunogenicity results, this cross-industry group was formed to establish harmonized recommendations and a develop a submission template to facilitate agency filings. Provided here are recommendations for reporting clinical anti-drug antibody (ADA) assay results using ligand-binding assay technologies. This publication describes the essential bioanalytical report (BAR) elements such as the method, critical reagents and equipment, study samples, results, and data analysis, and provides a template for a suggested structure for the ADA BAR. This publication focuses on the content and presentation of the bioanalytical ADA sample analysis report. The interpretation of immunogenicity data, including the evaluation of the impact of ADA on safety, exposure, and efficacy, is out of scope of this publication. Graphical Abstract

Xenoestrogen Status of Wuling Farm to Surrounding Water Bodies: An Application of Biochemical Parameters Using Onychostoma barbatulum - Lin-Yan Liao; Hui-Ling Cheng; Shu-Yin Wang; Shih-Hsiung Liang; Da-Ji Huang (Journal of Marine Science and Engineering, 2022)
The aim of this study was to apply biochemical parameters to Onychostoma barbatulum to understand whether Wuling Farm activities have caused organic pollution from xenoestrogens to flow into surrounding streams and thereby affected area aquatic ecosystems. Individuals of the Taiwan shovel-jaw carp (O. barbatulum) were collected by fyke netting in the Cijiawan, Kaoshan, and Yusheng Rivers in the protected area of Shei-Pa National Park and in the Ikawan River outside the protected areas from 4–5 June 2015 to 20–21 September 2015. The collected male individuals of O. barbatulum were divided into two groups. In the first group monooxygenase (Mon) activity, glutathione S-transferase (GST) activity, and vitellogenin (VTG) concentration in the liver were measured right after they were captured. Those in the second group were acclimated for 14 days and then exposed to 0 (control) or 10 ng/L 17β-estradiol for 10 days and then measured for changes in Mon, GST, and VTG in their livers. The value of VTG concentrations in O. barbatulum individuals collected from the Ikawan River was 2.12 ± 1.62 μg PO42+/g protein, which was the highest among all samples, followed by those collected from the Yusheng River (0.78 ± 1.00 μg PO42+/g protein). Individuals collected from the Yusheng River had the highest liver Mon activity (4.16 ± 1.08△A650/30 min/g protein) and the highest GST activity (1.58 ± 1.13 △A340/20 min/g protein), followed by those from the Ikawan River (Mon: 3.63 ± 1.13 △A650/30 min/g protein; GST: 1.24 ± 0.73 △A340/20 min/g protein). Comprehensive analyses showed that Mon and GST activities and VTG concentrations in livers measured right after being collected were lower than individuals exposed to 10 ng 17β-estradiol/L in the laboratory. Induced VTG concentrations were 9.87 ± 0.89 μg PO42+/g protein, Mon activity 8.02 ± 1.74 △A650/30 min/g protein, and GST activity 3.24 ± 0.62 △A340/20 min/g protein, indicating that farming activities have not significantly affected these aquatic organisms. However, pollution sources are still releasing pollutants containing xenoestrogens into the Yusheng River and Ikawan River. The impact of xenoestrogens is worthy of continuous long-term follow-up monitoring.

Bifunctional Ni@NiO catalyst supported on loofah sponge-derived carbon for electrocatalytic air oxidation of biorefractory pollutant in a coupling system - Min Sun; Xiong-Fei Tao; Sheng-Nan Tang; Jun Yu; Yan Wang; Lin-Feng Zhai (Environmental Science and Pollution Research, 2022)

Genome-wide identification of black pepper (Piper nigrum L.) Dof gene family and the differential gene screening in resistance to Phytophthora capsici - Fenju Zhang; Rui Fan; Lin Yan; Lisong Hu; Fan Su; Dewei Yang; Jing Li (Biologia, 2022)

Kelch-like protein 3 in human disease and therapy - Yan Lin; Qian Li; Xiaofeng Jin (Molecular Biology Reports, 2022)

Distribution characteristics of myxomycetes among substrates, study areas, and forest types in central China - Min Li; Yang Gao; Lei Yao; Gao-Wei Wang; Shu-Zhen Yan; Shuang-Lin Chen (Mycological Progress, 2022)

How will Chinese cities reduce their carbon emissions? Evidence from spatial differences - Junna Yan; Zhonghua Zhang; Mingli Chen; Tao Lin; Ke Yuan (Environmental Science and Pollution Research, 2022)

Reciprocal modulation between cigarette smoking and internet gaming disorder on participation coefficient within functional brain networks - Xianxin Qiu; Xu Han; Yao Wang; Weina Ding; Yawen Sun; Hao Lei; Yan Zhou; Fuchun Lin (Brain Imaging and Behavior, 2022)

Changes in plant anthocyanin levels in response to abiotic stresses: a meta-analysis - Wenjie Yan; Juanjuan Li; Xinyue Lin; Lina Wang; Xiaoxiao Yang; Xiangyu Xia; Yuxin Zhang; Shaoyu Yang; Hongbing Li; Xiping Deng; Qingbo Ke (Plant Biotechnology Reports, 2022)

Maintenance of Epstein-Barr virus latency through interaction of LMP2A with CXCR4 - Ni Qin; Yan Zhang; Lin Xu; Wen Liu; Bing Luo (Archives of Virology, 2022)

Functional characterization of two homologs of yeast acetyl-coenzyme A synthetase in the entomopathogenic fungus Beauveria bassiana - Jia-Hui Lei; Hai-Yan Lin; Jin-Li Ding; Ming-Guang Feng; Sheng-Hua Ying (Archives of Microbiology, 2022)

Effect of straw biochar from different crops on growth and nutrient uptake by peach (Prunus davidiana) seedlings - Qin Liu; Haoran Zhang; Yan Wang; Jing Sun; Dong Chen; Meiyan Tu; Lijin Lin (Acta Physiologiae Plantarum, 2022)

A novel mutation in HINT1 gene causes autosomal recessive axonal neuropathy with neuromyotonia, effective treatment with carbamazepine and review of the literature - Ling Xu; Guangyu Wang; Xiaoqing Lv; Dong Zhang; Chuanzhu Yan; Pengfei Lin (Acta Neurologica Belgica, 2022)

Potential and Distribution of Natural Gas Hydrate Resources in the South China Sea - Pibo Su; Lin Lin; Yaoyao Lv; Jinqiang Liang; Yunbao Sun; Wei Zhang; Huice He; Baiquan Yan; Zhanhuai Ji; Lifeng Wang; Feifei Wang; Mengya Cai (Journal of Marine Science and Engineering, 2022)
The amount of natural gas contained in the world’s gas hydrate accumulations is enormous, but these estimates remain highly speculative. So far, it is still challenging to locate spatial distribution of marine gas hydrate and quantitatively characterize the evaluation parameters and systematic improvement of evaluation systems. Considering the systematic review of the key accumulation factors, such as heat flow, deposition rate and total organic carbon in the typical passive continental margin, the evaluation results of global marine gas hydrate resources were analyzed based on the characteristics of gas hydrate geology, geophysics and geochemistry anomalies in the South China Sea. We analyze the problems on the evaluation of marine gas hydrate resources, probing into the geological characteristics and distribution laws of marine gas hydrate resources in the South China Sea, and estimate the parameters for in-place resource evaluation, in which the volume method based on Monte Carlo probability was used to evaluate the gas hydrate potential resources in the South China Sea. The probability distribution ranges from 37.6 billion (with 90% probability) to 117.7 billion (with 10% probability) tons of oil equivalent, with an expected value of 74.4 billion tons of oil equivalent. The study results show that the gas hydrate resource density in the South China Sea is similar to that in the typical sea areas, and the estimated global resources are basically consistent with the assessment results at this stag; this shows that the South China Sea has great potential for gas hydrate resources. The research results can provide guidance for the evaluation of global climate change and the exploration and development of hydrate resources.

Functional analysis of HADH c.99C>G shows that the variant causes the proliferation of pancreatic islets and leu-sensitive hyperinsulinaemia - Wu Long; Yue-Bing Wang; Peng-Fei Qu; Lin Ma; Si-Jie Wei; Yan-Mei Xi; Jin-Liang Du; Xue Tang; Kai Liu; Yu-Hua Li; Pu-Ping Lei (Journal of Genetics, 2022)

Absorptive Turbulent Seawater and Parameter Optimization of Perfect Optical Vortex for Optical Communication - Qingze Yan; Yixin Zhang; Lin Yu; Yun Zhu (Journal of Marine Science and Engineering, 2022)
In this paper, the optimization of perfect optical vortex (POV) parameter for underwater wireless optical communication link under M-QAM by average bit-error rate (ABER) and the effect of seawtaer turbulence on link information capacity are investigated. The link is absorbent, weakly turbulent, and bandwidth-limited. In investigating, we use the spectral absorption coefficient to describe the wavelength effect of seawater absorption. Specifically, under the paraxial approximation and Rytov approximation conditions, we define the average signal-to-noise-crosstalk ratio including the system bandwidth factor and derive the bandwidth-limited ABER of the OAM carrier link. Capitalizing on the defined average signal-to-noise crosstalk ratio and the derived bandwidth-limited ABER of link, the novel closed-form expression for the average information capacity of the perfect optical vortex link under M-QAM modulation is proposed. Through the numerical analysis of the ABER and the average information capacity, the POV optimization parameters in specific communication links are obtained and new conclusions are drawn that the average information capacity is restricted by both signal wavelength and the seawater absorption coefficient.

Transgenic expression of rice OsPHR2 increases phosphorus uptake and yield in wheat - Yan Li; Yuhui Fang; Chaojun Peng; Xia Hua; Yu Zhang; Xueli Qi; Zhengling Li; Yumin Wang; Lin Hu; Weigang Xu (Protoplasma, 2022)

The fibroblast growth factor receptor antagonist SSR128129E inhibits fat accumulation via suppressing adipogenesis in mice - Xinzhi Zhang; Xin Wen; Geng Hu; Qiang Zhang; Qianying Sun; Yanxin Jia; Yan Liu; Hai Lin; Haifang Li (Molecular Biology Reports, 2022)

Hippocampal Iron Accumulation Impairs Synapses and Memory via Suppressing Furin Expression and Downregulating BDNF Maturation - Yating Zhang; Xue Bai; Yi Zhang; Shanshan Yao; Yiduo Cui; Lin-Hao You; Peng Yu; Yan-Zhong Chang; Guofen Gao (Molecular Neurobiology, 2022)

Application of the prenatal BACs-on-Beads™ assay for rapid prenatal detection of sex chromosome mosaicism - Min Zhang; LingJi Chen; Meihuan Chen; Yan Wang; Bin Liang; Na Lin; Xiaoqing Wu; Linshuo Wang; Liangpu Xu; Hailong Huang (Molecular Genetics and Genomics, 2022)
The prenatal BACs-on-Beads™ (BoBs) assay was introduced for rapid detection of abnormalities of chromosomes 13, 18, 21, X, and Y and specific nine significant microdeletion syndromes. The ability of prenatal BoBs to detect mosaicism ranged from 20 to 40%. However, there have been no prenatal studies of sex chromosome mosaicism in prenatal BoBs. Therefore, the present study was performed with an aim to uncover the detection level of sex chromosome mosaicism that application of prenatal BoBs assay, and then to assess the sensitivity of prenatal BoBs assay, thereby improving the prenatal diagnostic accuracy. A total of 31 samples of amniotic fluid (AF) and umbilical cord blood (UCB) for prenatal diagnosis were collected, and the results were confirmed through karyotyping, single nucleotide polymorphism microarray (SNP-array) and copy number variation sequencing (CNV-seq). 23 cases of sex chromosome mosaicism were prompted abnormal by prenatal BoBs, the minimum detection level of mosaicism was about 6% as detected by karyotype. The overall sensitivity of prenatal BoBs in the detection of sex chromosome mosaicism was 74.2% (23/31). This study evaluated the effectiveness of prenatal BoBs for detecting sex chromosome mosaicism in prenatal diagnosis, and the results will provide valuable information for genetic counseling.

Extracellular histones induce inflammation and senescence of vascular smooth muscle cells by activating the AMPK/FOXO4 signaling pathway - Hang Yang; Yong-Yan Luo; Lue-Tao Zhang; Kai-Ran He; Xiao-Jun Lin (Inflammation Research, 2022)

Catalytic effect of cesium on the oxidation behavior of cation exchange resins in Li2CO3-Na2CO3-K2CO3 melt - Yang-Hai Zheng; Yong-De Yan; Yun Xue; Yue-Lin Wang; Xin Liu; Wan-Sheng Mi; Qing-Guo Zhang; Yu Li; Fu-Qiu Ma; Mi-Lin Zhang; Zhi-Hao Gan; Kai Zhu (Environmental Science and Pollution Research, 2022)

Environmental Kuznets curve for biodiversity loss: evidence from South and Southeast Asian countries - Yan-Ling Tan; Thian-Hee Yiew; Lin-Sea Lau; Ai-Lian Tan (Environmental Science and Pollution Research, 2022)

The influence of socioeconomic and environmental determinants on acute myocardial infarction (AMI) mortality from the spatial epidemiological perspective - Yan Wang; Bin Guo; Lin Pei; Hongjun Guo; Dingming Zhang; Xuying Ma; Yan Yu; Haojie Wu (Environmental Science and Pollution Research, 2022)

Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota - Xian-Feng Yang; Shao-Chen Yang; Fu-Li Wen; Lin Feng; Bo Meng; Hai-Yan Hu; Bao-Lin Wang; Jun Li; Alexandre J. Poulain; Ping Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Paleo-karst zone and its control on reservoirs in the fourth member of the Sinian Dengying formation in the Moxi area, central Sichuan Basin - Qinyu Xia; Haijun Yan; Wei Xu; Lin Zhang; Qian Li; Wenjun Luo; Hui Deng; Xun Zhu; Xinyu Li; Jichen Yu (Carbonates and Evaporites, 2022)

Erratum to: Stratospheric Ozone-induced Cloud Radiative Effects on Antarctic Sea Ice - Yan Xia; Yongyun Hu; Jiping Liu; Yi Huang; Fei Xie; Jintai Lin (Advances in Atmospheric Sciences, 2022)
Erratum to: Xia, Y., Y. Y. Hu, J. P. Liu, Y. Huang, F. Xie, and J. T. Lin, 2020: Stratospheric ozone-induced cloud radiative effects on Antarctic sea ice. Adv. Atmos. Sci. , 37 (5), 505−514, https://doi.org/10.1007/s00376-019-8251-6 . This article has changed from access by subscription to OA.

Ancylostoma ceylanicum Infection in a Miniature Schnauzer Dog Breed - Xu-Hui Lin; Hai-Ming Cai; Zhuan-Qiang Yan; Shen-Quan Liao; Min-Na Lv; Cai-Yan Wu; Juan Li; Jun-Jing Hu; Wen-Wan Xiao; Jian-Fei Zhang; Nan-Shan Qi; Ming-Fei Sun (Acta Parasitologica, 2022)

circRERE regulates the expression of GBX2 through miR-1299 and ZC3H13/N6-methyladenosine (m6A) to promote growth and invasion of hepatocellular carcinoma cells - Yong-hua Lin; Bao-yan Zhang; Zhi-chao Chen (Journal of Biosciences, 2022)

Influence of Indo-Pacific ocean currents on the distribution and demographic patterns of the brown seaweed Sargassum polycystum in tropical east Asia - Yanshuo Liang; Shuangshuang Zhang; Changxiang Yan; Stefano G. A. Draisma; Attachai Kantachumpoo; Zhao Li; Yude Lin; Jiang Zhu; Jie Zhang; Delin Duan (Frontiers in Marine Science, 2022)
Long-distance drifting of seaweeds driven by ocean currents is an ideal model for exploring population-level genetic connectivity and phylogeographic structure. In the Indo-Pacific convergence region, we integrated phylogeographic and ocean current data and Lagrangian particle simulations to explore how the ocean currents contributed to the biogeographical patterns and population genetic connectivity of Sargassum polycystum . The oceanographic transport and direction of gene flow was in line with contemporary ocean currents. The S. polycystum geographical dispersal from glacial refugia homogenized the footprint of genetic divergence. The multidisciplinary intersection provides insights into the evolutionary history and biogeographic conservation of tropical seaweeds in the Indo-Pacific convergence region.

Stachybotranes A–D, phenylspirodrimanes from the wetland fungus Stachybotrys chartarum with cytotoxic activities - Yan-Ru Bao; Han-Lin Feng; Xin-Sheng Yao (Natural Product Research, 2022)

Correction to: Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2022)

Combining Multiple Factors to Predict Alzheimer’s Disease - Xiao-Lin Gao; Jun Wang; Yan-Jiang Wang; Xian-Le Bu (Neuroscience Bulletin, 2022)

The IRE1/JNK signaling pathway regulates inflammation cytokines and production of glomerular extracellular matrix in the acute kidney injury to chronic kidney disease transition - Yan Liang; Lingyun Qu; Zhenjie Liu; Lulu Liang; Yingzi Wang; Songxia Quan; Yulin Wang; Lin Tang (Molecular Biology Reports, 2022)

Correction to: Alternate-day fasting alleviates high fat diet induced non-alcoholic fatty liver disease through controlling PPARα/Fgf21 signaling - Xinlei Liu; Yan Zhang; Chunya Ma; Juntang Lin; Jiang Du (Molecular Biology Reports, 2022)

Integrated Analyses of miRNome and Transcriptome Reveal the Critical Role of miRNAs Toward Heat Stress Response in Isochrysis galbana - Jia-Yi Cao; Si-Min Xu; Ying-Ying Wang; Xie-Dan Long; Shuo-Nan Ma; Cheng-Xu Zhou; Ji-Lin Xu; Xiao-Jun Yan (Marine Biotechnology, 2022)

Temporal specificity of IL-6 knockout in enhancing the thermogenic capability of brown adipose tissue - Mei Dong; Cheng Gao; Yanxin Jia; Weijia Xu; Yan Liu; Xin Wen; Qingxin Liu; Hai Lin; Haifang Li (Journal of Physiology and Biochemistry, 2022)

IL-38, a potential therapeutic agent for lupus, inhibits lupus progression - Wang-Dong Xu; Lin-Chong Su; Lu Fu; You-Yu Lan; Xiao-Yan Liu; Qi Huang; Qian Wu; Jie Zhou; An-Fang Huang (Inflammation Research, 2022)

Effects of ambient air pollution on glycosylated hemoglobin: a systematic review and meta-analysis - Li Tian; Mengqi Sun; Lisen Lin; Yan Wang; Yang Yu; Junchao Duan; Zhiwei Sun (Environmental Science and Pollution Research, 2022)

Removal effects and potential mechanisms of bisphenol A and 17α-ethynylestradiol by Biogenic Mn oxides generated by Bacillus sp. WH4 - Yan Lin; Hongchun Liu; Xiaojie Wang (Environmental Science and Pollution Research, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Cyclic experiments and global buckling design of steel-angle-assembled buckling-restrained braces - Jing-Zhong Tong; En-Yuan Zhang; Yan-Lin Guo; Chao-Qun Yu (Bulletin of Earthquake Engineering, 2022)

Sex differences in microstructural alterations in the corpus callosum tracts in drug-naïve children with ADHD - Qingxia Lin; Xuan Bu; Hong Chen; Yan Liang; Weiqian Wang; Yanhong Yi; Haixi Lin; Lu Lu; Yingxue Gao; Andan Qian; Shuangli Chen; Meihao Wang; et al. (Brain Imaging and Behavior, 2022)

Shoot organogenesis and somatic embryogenesis in leaf tissue of Pulsatilla tongkangensis Y.N. Lee & T.C. Lee - Xiao-mei Zhao; Yu-ji Lian; Ze-lin Jin; Xue-jie Zhang; Yan Y; Shou-jin Fan (Plant Biotechnology Reports, 2022)

Nematicidal activity of volatile organic compounds produced by Bacillus altitudinis AMCC 1040 against Meloidogyne incognita - Lin Ye; Jian-Yu Wang; Xiao-Fang Liu; Qi Guan; Nong-Xiao Dou; Jian Li; Qian Zhang; Yan-Ming Gao; Min Wang; Jian-She Li; Bo Zhou (Archives of Microbiology, 2022)

Rhodohalobacter sulfatireducens sp. nov., isolated from a marine solar saltern - Yu-Sheng Wang; Yu-Yan Yue; Yi-Lin Bai; Xu-Yang Zhang; Shuo Wang; Zong-Jun Du (Archives of Microbiology, 2022)

Plant secondary metabolite and temperature determine the prevalence of Arsenophonus endosymbionts in aphid populations - Chun‐Yan Chang; Xiao‐Wan Sun; Pan‐Pan Tian; Ning‐Hui Miao; Yu‐Lin Zhang; Xiang‐Dong Liu (Environmental Microbiology, 2022)
Summary Transmission rate and role in hosts contribute to the prevalence of an endosymbiont. However, factors affecting transmission and role of facultative endosymbionts are still not well understood. Here, we illustrated that host plants and environmental temperatures affected the transmission, relative abundance and role of Arsenophonus in the cotton aphid Aphis gossypii . The transmission rate of this endosymbiont from mother aphids to offspring was relatively lower. High temperatures impeded the transmission, and infection rates declined as aphids were exposed to 30°C. Contents of amino acids and secondary metabolites were remarkably different among host plants. Aphids feeding on zucchini leaves containing a higher titre of amino acids and lower secondary metabolites harboured a relatively lower abundance of Arsenophonus . Concentrations of an amino acid and a plant secondary metabolite, cucurbitacin B, in aphid diet were not associated with Arsenophonus abundance. However, gossypol, another plant secondary metabolite, was strongly related with the abundance. Arsenophonus imparted a fitness benefit to aphids, and the benefit was dependent on host plants and gossypol concentration. In sum, plant secondary metabolite and environmental temperature affect transmission, relative abundance and role of Arsenophonus , which determine the endosymbiont prevalence in aphid populations.

Systematic contributions of CFEM domain‐containing proteins to iron acquisition are essential for interspecies interaction of the filamentous pathogenic fungus Beauveria bassiana - Yue‐Jin Peng; Jia Hou; Hao Zhang; Jia‐Hui Lei; Hai‐Yan Lin; Jin‐Li Ding; Ming‐Guang Feng; Sheng‐Hua Ying (Environmental Microbiology, 2022)
Summary Common in fungal extracellular membrane (CFEM) domain is unique in fungal proteins and some of which contribute to iron acquisition in yeast. However, their roles in iron acquisition remain largely unknown in filamentous fungi. In this study, 12 CFEM‐containing proteins were bioinformatically identified in the filamentous entomopathogenic fungus Beauveria bassiana , and the roles of 11 genes were genetically characterized. Transmembrane helices were critical for their association with intracellular membranes, and their number varied among proteins. Eleven CFEM genes significantly contribute to vegetative growth under iron starvation and virulence. Notably, the virulence of most disruptants could be significantly weakened by a decrease in iron availability, in which the virulence of Δ Bbcfem7 and 8 strains was partially recovered by exogenous hemin. Δ Bbcfem7 and 8 mutants displayed defective competitiveness against the sister entomopathogenic fungus Beauveria brongniartii . All 11 disruptants displayed impaired growth in the antagonistic assay with the saprotrophic fungus Aspergillus niger , which could be repressed by exogenous ferric ions. These findings not only reveal the systematic contributions of CFEM proteins to acquire two forms of iron (i.e. heme and ferric ion) in the entire lifecycle of entomopathogenic fungi but also help to better understand the mechanisms of fungus–host and inter–fungus interactions.

Transcriptome study on immune response against Vibrio parahaemolyticus challenge in gill of abalone Haliotis discus hannai Ino - Yan Fang; Xiyun Yang; Shujuan Zhang; Xuyang Chen; Gang Lin; Yuqing Zhang; Mengjiao Wang; Mingzhu Li (Frontiers in Marine Science, 2022)
Abalone ( Haliotis discus hannai Ino) is one of the most vital economic shellfish cultured in China. However, bacterial and viral infection often leads to its high mortality and serious economic losses. In this study, transcriptome sequencing was performed on gill of abalone challenged by Vibrio parahaemolyticus for 0 h (control group, A0h), 8 h (A8h), and 48 h (A48h), respectively. Each library has an average of 53,361,675 clean reads. Approximately 85.71% reads were mapped to the reference genome of Haliotis discus hannai Ino. In comparison with A0h group, 7,656 and 2,789 genes were differentially expressed in the A8h and A48h groups, respectively. The differentially expressed genes (DEGs) were mostly enriched in oxidation–reduction process and oxidoreductase activity from GO analysis as well as immunity and metabolism-related pathways from Kyoto Encyclopedia of Genes and Genomes analysis. Cluster analysis demonstrated that all DEGs were categorized into eight subclusters by adopting the gene expression model. Specifically, a total of 1,070 significantly downregulated genes from two clusters were related to some metabolic pathways, ABC transporters, and cell adhesion. Moreover, 212 upregulated genes in one subcluster were enriched in several immune-related pathways, including nucleotide-binding oligomerization domain (NOD)-like receptor signaling pathway and apoptosis. Some members of the pattern recognition receptors family, which can initiate inflammatory signaling and induce apoptosis, were stimulated to upregulate in gill after challenge including C1q, perlucin, and low-density lipoprotein receptor–related protein. In addition, caspase-dependent apoptosis pathway was inactive, whereas caspase-independent apoptosis pathway was stimulating in response to Vibrio challenge. To eliminate invading pathogen, the immune effectors such as interleukin-17, matrix metalloproteinase, lysozyme, superoxide, and ferritin were also stimulated in gill. Moreover, this study also provides more information for comprehending the immunity and defense mechanisms against V. parahaemolyticus infection in abalone.

Meta-analysis of the effect of melatonin application on abiotic stress tolerance in plants - Xiaoxiao Yang; Jianhong Ren; Juanjuan Li; Xinyue Lin; Xiangyu Xia; Wenjie Yan; Yuxin Zhang; Xiping Deng; Qingbo Ke (Plant Biotechnology Reports, 2022)

Experimental study of energy and frequency characteristics of acoustic emissions induced from tensile and shear cracks in tunnel rockburst process - Yan-Bo Zhang; Peng Liang; Xu-Long Yao; Lin Sun; Bao-Zhu Tian; Xiang-Xin Liu (European Journal of Environmental and Civil Engineering, 2022)

Post-transcriptional control of bacterial nitrogen metabolism by regulatory noncoding RNAs - Yueyue Han; Chao Li; Yongliang Yan; Min Lin; Xiubin Ke; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2022)
Nitrogen metabolism is the most basic process of material and energy metabolism in living organisms, and processes involving the uptake and use of different nitrogen sources are usually tightly regulated at the transcriptional and post-transcriptional levels. Bacterial regulatory noncoding RNAs are novel post-transcriptional regulators that repress or activate the expression of target genes through complementarily pairing with target mRNAs; therefore, these noncoding RNAs play an important regulatory role in many physiological processes, such as bacterial substance metabolism and stress response. In recent years, a study found that noncoding RNAs play a vital role in the post-transcriptional regulation of nitrogen metabolism, which is currently a hot topic in the study of bacterial nitrogen metabolism regulation. In this review, we present an overview of recent advances that increase our understanding on the regulatory roles of bacterial noncoding RNAs and describe in detail how noncoding RNAs regulate biological nitrogen fixation and nitrogen metabolic engineering. Furthermore, our goal is to lay a theoretical foundation for better understanding the molecular mechanisms in bacteria that are involved in environmental adaptations and metabolically-engineered genetic modifications.

An Adequate Supply of Bis(ethylmaltolato)oxidovanadium(IV) Remarkably Reversed the Pathological Hallmarks of Alzheimer’s Disease in Triple-Transgenic Middle-Aged Mice - Zhijun He; Lin Zheng; Xu Zhao; Xiaoqian Li; Hua Xue; Qionghui Zhao; Bingyu Ren; Nan Li; Jiazuan Ni; Yan Zhang; Qiong Liu (Biological Trace Element Research, 2022)

Testing the transfer functions for the Geonor T-200B and Chinese standard precipitation gauge in the central Qinghai—Tibet Plateau - Le-le Zhang; Li-ming Gao; Ji Chen; Lin Zhao; Ke-long Chen; Jing-yi Zhao; Guo-jun Liu; Ting-xi Song; Yan-kun Li (Journal of Mountain Science, 2022)

Insight rifampicin-resistant (rpoB) mutation in Pseudomonas stutzeri leads to enhance the biosynthesis of secondary metabolites to survive against harsh environments - Khandakar Mohiul Alam; Yongliang Yan; Min Lin; Md. Ariful Islam; Ahmed Gaber; Akbar Hossain (Archives of Microbiology, 2022)

Aquapteridospora jiangxiensis, a new aquatic hyphomycetous fungus from a freshwater habitat in China - Su-Qin Peng; Yu-Lin Liu; Jun-En Huang; Xiao-Hong Li; Xin-Yi Yan; Hai-Yan Song; Yang Gao; Zhi-Jun Zhai; Yuan-Qiu Liu; Dian-Ming Hu (Archives of Microbiology, 2022)

Distributions of the Non-Native Mangrove Sonneratia apetala in China: Based on Google Earth Imagery and Field Survey - Jialin Zhang; Qiulian Lin; Yisheng Peng; Lianghao Pan; Yan Chen; Yun Zhang; Luzhen Chen (Wetlands, 2022)

Low-carbon stabilization/solidification of municipal solid waste incineration fly ash - Chen Sun; Lei Wang; Xiaoqing Lin; Shengyong Lu; Qunxing Huang; Jianhua Yan (Waste Disposal & Sustainable Energy, 2022)

Bedside Diagnosis for Disseminated Deep Dermatophytosis: a Case Series Study - Xiu-Jiao Xia; Hong Shen; Hui-Lin Zhi; Yan Zhong; Bo Sang; Wen-Wen Lv; Qiu-Ping Li; Ze-Hu Liu (Mycopathologia, 2022)

Molecular cloning, characterization and expression analysis of two 12-oxophytodienoate reductases (NtOPR1 and NtOPR2) from Nicotiana tabacum - Feiyan Huang; Farhat Abbas; Dylan O’Neill Rothenberg; Muhammad Imran; Sajid Fiaz; Naveed ur Rehman; Sikandar Amanullah; Afifa Younas; Yan Ding; Xianjie Cai; Xiaolong Chen; Lei Yu; et al. (Molecular Biology Reports, 2022)

A Combined Proteomics and Metabolomics Profiling to Investigate the Genetic Heterogeneity of Autistic Children - Liming Shen; Huajie Zhang; Jing Lin; Yan Gao; Margy Chen; Naseer Ullah Khan; Xiaoxiao Tang; Qi Hong; Chengyun Feng; Yuxi Zhao; Xueshan Cao (Molecular Neurobiology, 2022)

Dynamics of soil organic carbon in different-sized aggregates under splash erosion - Junqiu Lin; Nufang Fang; Yan Zhang; Yi Zeng; Daming Yang; Wei Dai; Ling Wang; Zhihua Shi (Journal of Soils and Sediments, 2022)

Long-term exercise pre-training attenuates Alzheimer’s disease–related pathology in a transgenic rat model of Alzheimer’s disease - Luodan Yang; Chongyun Wu; Yong Li; Yan Dong; Celeste Yin-Chieh Wu; Reggie Hui-Chao Lee; Darrell W. Brann; Hung Wen Lin; Quanguang Zhang (GeroScience, 2022)

Analyzing the mechanism of nitrous oxide production in aerobic phase of anoxic/aerobic sequential batch reactor from the perspective of key enzymes - Rui Yang; Lin-jiang Yuan; Ru Wang; Zhi-xian He; Lin Lei; Yan-chen Ma (Environmental Science and Pollution Research, 2022)

miR-21-5p serves as a promoter in renal cell carcinoma progression through ARHGAP24 downregulation - Bin Meng; Pengfei Wang; Chaofei Zhao; Guangwei Yin; Xin Meng; Lin Li; Shengyong Cai; Chengquan Yan (Environmental Science and Pollution Research, 2022)

A comparative study on the model of PM2.5 direct or indirect interaction with bronchial epithelial cells - Yan Wang; Xin Zuo; Fuyang Jiang; Lin Hou; Qiyue Jiang; Zhonghui Zhu; Lin Tian (Environmental Science and Pollution Research, 2022)

Characterizing sediment bacterial community and identifying the biological indicators in a seawater-freshwater transition zone during the wet and dry seasons - Yongbin Li; Duanyi Huang; Weimin Sun; Xiaoxu Sun; Geng Yan; Wenlong Gao; Hanzhi Lin (Environmental Science and Pollution Research, 2022)

Astragalus Polysaccharides Reduce High-glucose-induced Rat Aortic Endothelial Cell Senescence and Inflammasome Activation by Modulating the Mitochondrial Na+/Ca2+ Exchanger - Xin-Yu Miao; Xiao-Xiao Zhu; Zhao-Yan Gu; Bo Fu; Shao-Yuan Cui; Yuan Zu; Ling-Jun Rong; Fan Hu; Xiang-Mei Chen; Yan-Ping Gong; Chun-Lin Li (Cell Biochemistry and Biophysics, 2022)

Investigation on long-term progressive deformation of engineering slope based on comprehensive monitoring - Shi-shu Zhang; Song-feng Guo; Sheng-wen Qi; Feng-jiao Tang; Jin-shan Hu; Xiao-ping Zhao; Cong-yan Ran; Xin Wang; Yu Zou; Xiao-lin Huang; Bo-wen Zheng; Ning Liang (Journal of Mountain Science, 2022)

Role of Temperature in Sludge Composting and Hyperthermophilic Systems: a Review - Zhiquan Wang; Deyi Wu; Yan Lin; Xinze Wang (BioEnergy Research, 2022)

Double-phase-shift filtering method for harmonic elimination based on AR2U-Net - Bo-Lin Li; Yan-Chun Wang; Hang Yuan; Xue-Qing Liu (Applied Geophysics, 2022)

Toxic encephalopathy induced by radix Sophorae tonkinensis - Xue-Lin Li; Hao-Tian Zhao; Jinming Han; Zhong-Rui Yan; Hai-Yang Wang (Acta Neurologica Belgica, 2022)

Optimization of aquaculture sustainability through ecological intensification in China - Shuang‐lin Dong; Yun‐wei Dong; Ling Cao; Johan Verreth; Yngvar Olsen; Wen‐jing Liu; Qi‐zhi Fang; Yan‐gen Zhou; Li Li; Jing‐yu Li; Yong‐tong Mu; Patrick Sorgeloos (Reviews in Aquaculture, 2022)
As the world's leading producer of farmed aquatic food products, China faces great uncertainty concerning the further sustainable development of its aquaculture industry due to high and increasing pressure from environmental and resource constraints. To realize truly sustainable development, it is imperative to establish an evaluation system that integrates social, economic, environmental and resource criteria, and optimizes aquaculture systems through a holistic approach. Here, we used analytical hierarchy processes combined with expert judgment and objective data to assess the sustainability of 10 major aquaculture production systems (APSs) in China. Based on the evaluation results, we propose the ecological intensification of aquaculture systems (ELIAS), rationally integrating anthropogenic inputs with aquaculture ecosystem services, to improve the sustainability of APSs. The holistic evaluation system and ELIAS are fundamental and critical for the future development of aquaculture in China and globally.

Cover Image, Volume 14, Issue 3 - Shuang‐lin Dong; Yun‐wei Dong; Ling Cao; Johan Verreth; Yngvar Olsen; Wen‐jing Liu; Qi‐zhi Fang; Yan‐gen Zhou; Li Li; Jing‐yu Li; Yong‐tong Mu; Patrick Sorgeloos (Reviews in Aquaculture, 2022)
The cover image is based on the Review Article Optimization of aquaculture sustainability through ecological intensification in China by Shuang‐lin Dong et al., https://doi.org/10.1111/raq.12648 image

Risk Assessment of Navigation Safety for Ferries - Wen-Kai K. Hsu; Jun-Wen Chen; Nguyen Tan Huynh; Yan-You Lin (Journal of Marine Science and Engineering, 2022)
This study aims to discuss a risk assessment of navigation safety for ferries. In this research, the risk factors (RFs) for the navigation safety of ferries are first investigated from relevant literature and ferry operational features. A fuzzy AHP (Analytic Hierarchical Process) approach is then proposed to weight those RFs, after which a continuous risk-matrix model is then developed to determine the RFs’ risk levels. Finally, to validate the practical application of the proposed model, ferries traveling across the Taiwan Strait were empirically investigated. The results may provide practical information for ferry operators to improve their safety performances. Further, the proposed risk assessment approach may provide references for related research in the safety management of short-distance passenger ships.

Complete genome sequence of a novel chlorobenzene degrader, Burkholderia stabilis TF-2 - Xiao-Ping Zhang; Yan-Hui Gao; Zhi-Lin Xing; Yong-Qiong Wang; Tian-Tao Zhao (Biologia, 2022)

Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model - Wan-yi Li; Jun-yan Gao; Su-Yang Lin; Shao-tao Pan; Biao Xiao; Yu-tao Ma; Kai Xie; Wei Shen; Zhi-tao Liu; Guang-yu Li; Jie-jie Guo; Qin-wen Wang; et al. (Molecular Neurobiology, 2022)

Interleukin-13 Affects the Recovery Processes in a Mouse Model of Hemorrhagic Stroke with Bilateral Tibial Fracture - Ya’nan Yan; Cheng Gao; Guang Chen; Xueshi Chen; Yanglin Wu; Heng Xu; Zhiqi Cheng; Chengliang Luo; Mingyang Zhang; Tao Wang; Jun Lin; Xiping Chen; et al. (Molecular Neurobiology, 2022)

Metabolic tuning of a stable microbial community in the surface oligotrophic Indian Ocean revealed by integrated meta-omics - Zhang-Xian Xie; Ke-Qiang Yan; Ling-Fen Kong; Ying-Bao Gai; Tao Jin; Yan-Bin He; Ya-Yu Wang; Feng Chen; Lin Lin; Zhi-Long Lin; Hong-Kai Xu; Zong-Ze Shao; et al. (Marine Life Science & Technology, 2022)
Understanding the mechanisms, structuring microbial communities in oligotrophic ocean surface waters remains a major ecological endeavor. Functional redundancy and metabolic tuning are two mechanisms that have been proposed to shape microbial response to environmental forcing. However, little is known about their roles in the oligotrophic surface ocean due to less integrative characterization of community taxonomy and function. Here, we applied an integrated meta-omics-based approach, from genes to proteins, to investigate the microbial community of the oligotrophic northern Indian Ocean. Insignificant spatial variabilities of both genomic and proteomic compositions indicated a stable microbial community that was dominated by Prochlorococcus , Synechococcus , and SAR11. However, fine tuning of some metabolic functions that are mainly driven by salinity and temperature was observed. Intriguingly, a tuning divergence occurred between metabolic potential and activity in response to different environmental perturbations. Our results indicate that metabolic tuning is an important mechanism for sustaining the stability of microbial communities in oligotrophic oceans. In addition, integrated meta-omics provides a powerful tool to comprehensively understand microbial behavior and function in the ocean.

First report of Euphorbia leaf curl virus infecting Passiflora edulis in Fujian province, China - Ting Ye; Guo-Hua Zheng; Ying Guo; Yan-Lin Ming (Journal of Plant Pathology, 2022)

Community structure and assembly of denitrifying bacteria in epiphytic biofilms in a freshwater lake ecosystem - Guoqing Li; Dingbo Yan; Pinhua Xia; Haipeng Cao; Tao Lin; Yin Yi (Journal of Oceanology and Limnology, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

The genes for sensory perception of sound should be considered in gene diagnosis of congenital sensorineural hearing loss and microtia - Ken Lin; Ding-Yun You; Li-Huan Zhang; Li-Juan Zhou; Jin-Yan Zu; Yang Xiao; Mei-Hua Sun; Dong-Su; Xue Cao; Tie-Song Zhang; Jing Ma (Journal of Applied Genetics, 2022)

Baculoviruses hijack the visual perception of their caterpillar hosts to induce climbing behaviour thus promoting virus dispersal - Xiaoming Liu; Zhiqiang Tian; Limei Cai; Zhongjian Shen; J. P. Michaud; Lin Zhu; Shuo Yan; Vera I. D. Ros; Kelli Hoover; Zhen Li; Songdou Zhang; Xiaoxia Liu (Molecular Ecology, 2022)
Baculoviruses can induce climbing behaviour in their caterpillar hosts to ensure they die at elevated positions to enhance virus transmission, providing an excellent model to study parasitic manipulation of host behaviour. Here, we demonstrate that climbing behaviour occurred mostly during daylight hours, and that the height at death of Helicoverpa armigera single nucleopolyhedrovirus (HearNPV)‐infected larvae increases with the height of the light source. Phototaxic and electroretinogram (ERG) responses were enhanced after HearNPV‐infection in host larvae, and ablation of stemmata in infected larvae prevented both phototaxis and climbing behaviour. Through transcriptome and quantitative PCR, we confirmed that two opsin genes (a blue light‐sensitive gene, HaBL ; and a long wave‐sensitive gene, HaLW ) as well as the TRPL (transient receptor potential‐like channel protein) gene, all integral to the host's visual perception pathway, were significantly upregulated after HearNPV infection. Knockout of HaBL , HaLW , or TRPL genes using the CRISPR/Cas9 system resulted in significantly reduced ERG responses, phototaxis, and climbing behaviour in HearNPV‐infected larvae. These results reveal that HearNPV alters the expression of specific genes to hijack host visual perception at fundamental levels—photoreception and phototransduction—in order to induce climbing behaviour in host larvae.

Soil phosphorus drives plant trait variations in a mature subtropical forest - Erqian Cui; Ruiling Lu; Xiaoni Xu; Huanfa Sun; Yang Qiao; Jiaye Ping; Shuying Qiu; Yihua Lin; Jiehuan Bao; Yutong Yong; Zemei Zheng; Enrong Yan; et al. (Global Change Biology, 2022)
Earth system models are implementing soil phosphorus dynamic and plant functional traits to predict functional changes in global forests. However, the linkage between soil phosphorus and plant traits lacks empirical evidence, especially in mature forests. Here, we examined the soil phosphorus constraint on plant functional traits in a mature subtropical forest based on observations of 9943 individuals from 90 species in a 5‐ha forest dynamic plot and 405 individuals from 15 species in an adjacent 10‐year nutrient‐addition experiment. We first confirmed a pervasive phosphorus limitation on subtropical tree growth based on leaf N:P ratios. Then, we found that soil phosphorus dominated multidimensional trait variations in the 5‐ha forest dynamic plot. Soil phosphorus content explained 44% and 53% of the variance in the traits defining the main functional space across species and communities, respectively. Lastly, we found much stronger phosphorus effects on most plant functional traits than nitrogen at both species and community levels in the 10‐year nutrient‐addition experiment. This study provides evidence for the consistent pattern of soil phosphorus constraint on plant trait variations between the species and community levels in a mature evergreen broadleaf forest in the East Asian monsoon region. These findings shed light on the predominant role of soil phosphorus on plant functional trait variations in mature subtropical forests, providing new insights for models to incorporate soil phosphorus constraint in predicting future vegetation dynamics.

Evolutionary and ecological patterns of scatter‐ and larder‐hoarding behaviours in rodents - Yongjun Zhang; Fei Yu; Xianfeng Yi; Weiwei Zhou; Rui Liu; Marcel Holyoak; Lin Cao; Mingming Zhang; Jiani Chen; Zhibin Zhang; Chuan Yan (Ecology Letters, 2022)
Scatter‐ and larder hoarding are the primary strategies of food‐hoarding animals and have important implications for plant‐animal interactions and plant recruitment. However, their origins and influencing factors have not been fully investigated across a wide range of taxa. Our systematic literature search amassed data for 183 seed‐hoarding rodent species worldwide and tested relationships of seed‐hoarding behaviours with phylogenetic signal, functional traits and environmental factors. We found that the evolution of hoarding strategies was not random in phylogeny, and scatter hoarding originated independently multiple times from larder hoarding. Rodents with higher encephalisation quotient (relative brain size), omnivorous diet (related to dependence on seeds) and inhabiting lower latitudes were disproportionately likely to scatter hoard. Despite body mass’s potential relationship with competition through food defence, it was associated with food‐hoarding strategy only in a few families. Our results show the need to study the community and ecological context of food‐hoarding behaviours.

Composition, Demographic History, and Population Structures of Trichiurus - Kui-Ching Hsu; Mu-Rong Yi; Sui Gu; Xiong-Bo He; Zhi-Sen Luo; Bin Kang; Hung-Du Lin; Yun-Rong Yan (Frontiers in Marine Science, 2022)
Sequences of the complete mitochondrial cytochrome oxidase subunit I gene were used to identify Trichiurus species and examine their population genetic structure and demographic history along the coast of China. Three Trichiurus species were found. Trichiurus japonicus lives in colder waters along the continental shelves in the China Seas, while Trichiurus nanhaiensis lives warmer waters along continental slopes in the South China Sea, and Trichiurus brevis lives in shallow and warmer waters in the South China Sea. The migrations of these species were mainly associated with feeding and spawning preferences. Two major wintering and spawning grounds in the East China Sea and South China Sea were found. All species showed a lack of population genetic structure resulting from their oceanodromous life cycle (the degree of population substructure index N ST = 0.000–0.149), but the results of approximate Bayesian computational approaches suggested population declines or stabilization and differentiation. The results of the T MRCA (time to the most recent common ancestor) showed that during glaciations, the Yellow Sea and the East China Sea were completely exposed, and the South China Sea acted as a refugium. Thus, the populations of these three species experienced differentiation during glaciations. This study also examined the limitations of Bayesian skyline plot analysis.

Blood Transcriptome Analysis Reveals Gene Expression Differences between Yangtze Finless Porpoises from Two Habitats: Natural and Ex Situ Protected Waters - Wang Liu; Denghua Yin; Danqing Lin; Yan Yan; Xiaoyan Zhu; Congping Ying; Jialu Zhang; Pao Xu; Kai Liu (Fishes, 2022)
The Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis, YFP) is a critically endangered small odontocete species, mainly distributed in the middle and lower reaches of the Yangtze River, Poyang Lake, and Dongting Lake. Under the influence of human activities, many factors are threatening the survival and reproduction of YFPs in their natural habitat. Ex situ conservation is of great significance to strengthen the rescuing conservation of YFPs by providing suitable alternative habitats and promoting the reproduction and growth of the ex situ population. To reveal the differences in gene expression of YFPs in natural and ex situ protected waters, and to investigate the effects of environmental factors on YFPs and their mechanisms, we performed transcriptome sequencing for blood tissues of YFPs collected from natural waters and ex situ protected waters. Using RNA-seq we identified 4613 differentially expressed genes (DEGs), of which 4485 were up-regulated and 128 were down-regulated in the natural population. GO analysis showed that DEGs were significantly enriched in entries related to binding, catalytic activity, and biological regulation; KEGG analysis showed that DEGs were enriched mainly in signal transduction, endocrine system, immune system, and sensory system-related pathways. Further analysis revealed that water pollution in natural waters may affect the hormone secretion of YFPs by altering the expression pattern of endocrine genes, thus interfering with normal endocrine activities; noise pollution may induce oxidative stress and inflammatory responses in YFPs, thus impairing the auditory function of YFPs. This study provides a new perspective for further research on the effect of habitat conditions on the YFPs and suggests that improving the habitat environment may help in the conservation of YFPs.

Berberisides A-D: three novel prenylated benzoic acid derivatives and a clerodane glycoside from Berberis tsarica aherndt. - Zhao-Yue Dong; Qing-Hong Zeng; Lin Wei; Xin Guo; Yan Sun; Fan-Cheng Meng; Guo-Wei Wang; Xiao-Zhong Lan; Zhi-Hua Liao; Min Chen (Natural Product Research, 2022)

Genetic Diversity Analysis of Sugarcane (Saccharum spp. hybrids) Among High-Sucrose Clones of GT Series and Commonly Used Parents by Using Microsatellite Markers in Guangxi, China - Hai-Rong Huang; Yi-Jing Gao; Mukesh Kumar Malviya; Krishan K. Verma; Manoj Kumar Solanki; Yu-Xin Huang; Xiang Li; Yuchi Deng; Jing Yan; Shi-Yun Tang; Lun-Wang Wang; Lin Xu (Sugar Tech, 2022)

Overview of yeast environmental stress response pathways and the development of tolerant yeasts - Nai-Xin Lin; Yan Xu; Xiao-Wei Yu (Systems Microbiology and Biomanufacturing, 2022)

Alternate-day fasting alleviates high fat diet induced non-alcoholic fatty liver disease through controlling PPARα/Fgf21 signaling - Xinlei Liu; Yan Zhang; Chunya Ma; Juntang Lin; Jiang Du (Molecular Biology Reports, 2022)

Heat Shock Procedure Affects Cell Division-Associated Genes in Gynogenetic Manipulation - Fan Yu; Jian-Lin Li; Wen-Rong Feng; Yong-Kai Tang; Sheng-Yan Su; Pao Xu; Huan Zhong (Marine Biotechnology, 2022)

Comparative metabolomics provides novel insights into the basis of petiole color differences in celery (Apium graveolens L.) - Mengyao Li; Jie Li; Haohan Tan; Ya Luo; Yong Zhang; Qing Chen; Yan Wang; Yuanxiu Lin; Yunting Zhang; Xiaorong Wang; Haoru Tang (Journal of Zhejiang University-SCIENCE B, 2022)

Identification and expression profiling of HSP20 genes in Neoporphyra haitanensis - Ling-Na Peng; Lin-Bin Huang; Tian-Yu Gui; Da-Hai Gao; Xing-Hong Yan (Journal of Applied Phycology, 2022)

Ore-forming age and tectonic setting of the Linjiasandaogou gold deposit in the Liaodong Peninsula, northeast China: constraints from geochronology and geochemistry - Xiaofeng Yao; Tingjie Yan; Zhicheng Lü; Chenggui Lin; Kuifeng Mi; Shenghui Li; Yang Li; Wange Du (Acta Geochimica, 2022)

A review on food processing and preparation methods for altering fish allergenicity - Binaka Prabashini Dasanayaka; Zhenxing Li; Siddanakoppalu Narayana Pramod; Yan Chen; Mati Ullah Khan; Hong Lin (Critical Reviews in Food Science and Nutrition, 2022)

Sterols and triterpenoids from Ganoderma lucidum and their reversal activities of tumor multidrug resistance - Min Wu; Cui-e Shen; Qiao-fa Lin; Jin-yi Zhong; Yan-fei Zhou; Ben-chen Liu; Jian-hua Xu; Zhi-qiang Zhang; Peng Li (Natural Product Research, 2022)

The management of bone defect using long non-coding RNA as a potential biomarker for regulating the osteogenic differentiation process - Jia-lin Liu; Yan-shi Liu; Mei-jie Zheng; Hui-yu He (Molecular Biology Reports, 2022)
Tissue engineered bone brings hope to the treatment of bone defects, and the osteogenic differentiation of stem cells is the key link. Inducing osteogenic differentiation of stem cells may be a potential approach to promote bone regeneration. In recent years, lncRNA has been studied in the field increasingly, which is believed can regulate cell cycle, proliferation, metastasis, differentiation and immunity, participating in a variety of physiology and pathology processes. At present, it has been confirmed that certain lncRNAs regulate the osteogenesis of stem cells and take part in mediating signaling pathways including Wnt/β-catenin, MAPK, TGF-β/BMP, and Notch pathways. Here, we provided an overview of lncRNA, reviewed its researches in the osteogenic differentiation of stem cells, emphasized the importance of lncRNA in bone regeneration, and focused on the roles of lncRNA in signaling pathways, in order to make adequate preparations for applying lncRNA to bone tissue Engineering, letting it regulate the osteogenic differentiation of stem cells for bone regeneration.

Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol - Lin-Hui Ma; Jie Wan; Jing Yan; Ning Wang; Yan-Ping Liu; Hai-Bi Wang; Cheng-Hua Zhou; Yu-Qing Wu (Molecular Neurobiology, 2022)

The effect of preoperative statin treatment on acute kidney injury in elderly patients undergoing valve replacement surgery - Bing-qi Fu; Xue-biao Wei; Zedazhong Su; Ying-wen Lin; Zu-hui Ke; Tong Tan; Ji-yan Chen; Shou-hong Wang; Dan-qing Yu (European Journal of Clinical Pharmacology, 2022)

Response to Antibiotic exposure and risk of type 2 diabetes mellitus: a systematic review and meta-analysis by Maryam et al. (2021) by J Zhou and K Chen (2021) - Jielin Zhou; Yan Lin; Yong Liu; Keyang Chen (Environmental Science and Pollution Research, 2022)

Evaluation on explosion characteristics and parameters of pulverized coal for low-quality coal: experimental study and analysis - Hongwei Yan; Baisheng Nie; Chao Peng; Peijun Liu; Xiaotong Wang; Feifei Yin; Jie Gong; Yueying Wei; Shuangshuang Lin; Qiang Gao; Mingwei Cao (Environmental Science and Pollution Research, 2022)

Analysis of geomorphologic features of the circular structure in the south of Lufeng Dinosaur Valley - Hu Lin; Gan Shu; Yuan Xiping; Yang MingLong; Gao Sha; Bi Rui; Li Yan (Earth Science Informatics, 2022)

A general characterization of representing spatiotemporal data and determining topological relations based on OWL - Xiangfu Meng; Lin Zhu; Yan Wang; Xiaoyan Zhang (Earth Science Informatics, 2022)

Estimation of permafrost thermal behavior using Fourier series model - Yan-yu Zhang; Shu-ying Zang; Lin Zhao; Da-long Ma; Yue Lin; Hao Li (Journal of Mountain Science, 2022)

Consistency correction of echo intensity data for multiple radar systems and its application in quantitative estimation of typhoon precipitation - Shuai Zhang; Jing Han; Bingke Zhao; Zhigang Chu; Jie Tang; Limin Lin; Xiaoqin Lu; Jiaming Yan (Frontiers of Earth Science, 2022)

Description of Aureibaculum luteum sp. nov. and Aureibaculum flavum sp. nov. isolated from Antarctic intertidal sediments - Xiao-yan He; Ning-hua Liu; Chao-yi Lin; Mei-ling Sun; Xiu-lan Chen; Yu-zhong Zhang; Yu-qiang Zhang; Xi-ying Zhang (Antonie van Leeuwenhoek, 2022)

Comprehensive review on catalytic degradation of Cl-VOCs under the practical application conditions - Fawei Lin; Li Xiang; Zhiman Zhang; Na Li; BeiBei Yan; Chi He; Zhengping Hao; Guanyi Chen (Critical Reviews in Environmental Science and Technology, 2022)

Perchlorate contamination of tea leaves and a corresponding probabilistic dietary risk assessment using Monte Carlo simulation - Qinghua Yao; Sun-an Yan; Wenjing Liu; Minmin Huang; Qiu Lin (Food Additives & Contaminants: Part A, 2022)

Correction to: Comparative chloroplast genomes of Prunus subgenus Cerasus (Rosaceae): insights into sequence variations and phylogenetic relationships - Jiawen Yan; Jianhui Li; Lin Yu; Wenfu Bai; Dongling Nie; Ying Xiong; Sizheng Wu (Tree Genetics & Genomes, 2022)

Full-Length Transcriptome of Red Swamp Crayfish Hepatopancreas Reveals Candidate Genes in Hif-1 and Antioxidant Pathways in Response to Hypoxia-Reoxygenation - Yu Xu; Hai Lin; Weihui Yan; Jiajia Li; Mengling Sun; Jiaping Chen; Zhiqiang Xu (Marine Biotechnology, 2022)

Exploration on long-term acclimation of Pyropia haitanensis thalli to monochromatic lights based on physiological characteristics and transcriptome analysis - Xiaojun Liang; Chenhui Zhong; Longchen Tang; Qi Lin; Xinghong Yan (Journal of Applied Phycology, 2022)

Evaluation of reference genes for normalization of mRNA and microRNA expression by RT-qPCR under different experimental conditions in Medicago ruthenica (L.) Ledeb. - Mao-Wei Guo; Lin Zhu; Hong-Yan Li; Zi-Nian Wu; Zhi-Yong Li; Jun Li (Genetic Resources and Crop Evolution, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Species richness and generalists–specialists mosaicism of symbiodiniacean symbionts in corals from Hong Kong revealed by high-throughput ITS sequencing - Osama S. Saad; Xin Lin; Tsz Yan Ng; Ling Li; Put Ang; Senjie Lin (Coral Reefs, 2022)

Quantitative synthetic MRI reveals grey matter abnormalities in children with drug-naïve attention-deficit/hyperactivity disorder - Shu Su; Yingqian Chen; Yan Dai; Liping Lin; Long Qian; Qin Zhou; Mengsha Zou; Hongyu Zhang; Meina Liu; Xianhong Xiang; Zhiyun Yang (Brain Imaging and Behavior, 2022)

Evaluation of suitable qRT-PCR normalization genes for various citrus rootstocks - Wen He; Rui Xie; Huan Li; Yan Wang; Qing Chen; Yuanxiu Lin; Yunting Zhang; Ya Luo; Yong Zhang; Haoru Tang; Xiaorong Wang (Plant Biotechnology Reports, 2022)

Multivariate analysis of the spatial species diversity of demersal fish assemblages in relation to habitat characteristics in a subtropical national park, Taiwan - Kuo-Shu Chen; Hsu-Sen Chen; Chiee-Young Chen; Yan-Lin Su; Pei-Jie Meng; Meng-Hsien Chen (Marine Biodiversity, 2022)
To understand the spatial species diversity of demersal fish assemblages in Taijiang National Park (TJNP) of Taiwan, fishes from 44 demersal trawl hauls and environmental data were collected in the nearshore and offshore areas of TJNP from April 2016 to May 2019. In total, fishes of 47 families, 84 genera, and 113 species were recorded. The nearshore and offshore demersal fish assemblages in TJNP exhibited significant variability in species composition assessed via beta diversity. Using distance-based redundancy analysis, we demonstrated that bottom depth and substrate type were significant explanatory variables of spatial species diversity and identified three habitat types (I: shallow soft bottom; II: deeper soft bottom; III: deeper bottom with mixed sand and gravel substrates). The nearshore assemblage was characterized by type I, where Tarphops oligolepis (flounder), Trachinocephalus myops (snakefish), and Liachirus melanospilos (carpet sole) dominated in terms of abundance. The offshore assemblage was characterized by either type II or type III because differences in substrate types among sampling sites were noticeable. At the offshore sites characterized by a deeper soft bottom (type II), Johnius distinctus (croaker), Cynoglossus kopsii (shortheaded tonguesole), and Coelorinchus formosanus (Formosa grenadier) predominated. In contrast, the westernmost sampling site, characterized by type III habitat, exhibited relatively high Shannon indices, and Scorpaena miostoma (scorpionfish), Urolophus aurantiacus (sepia stingray), and Parabothus taiwanensis (lefteye flounder) predominated. Our results provide the first baseline information on the environmental characteristics and spatial species diversity of demersal fish assemblages in TJNP and have implications for biodiversity conservation in existing spatial management areas.

Climate warming promotes deterministic assembly of arbuscular mycorrhizal fungal communities - Xinyu Xu; Yunpeng Qiu; Kangcheng Zhang; Fei Yang; Mengfei Chen; Xi Luo; Xuebin Yan; Peng Wang; Yi Zhang; Huaihai Chen; Hui Guo; Lin Jiang; et al. (Global Change Biology, 2022)
Arbuscular mycorrhizal fungi (AMF) significantly contribute to plant resource acquisition and play important roles in mediating plant interactions and soil carbon (C) dynamics. However, it remains unclear how AMF communities respond to climate change. We assessed impacts of warming and precipitation alterations (30% increase or decrease) on soil AMF communities, and examined major ecological processes shaping the AMF community assemblage in a Tibetan alpine meadow. Our results showed that warming significantly increased root biomass, and available nitrogen (N) and phosphorus (P) in soil. While precipitation alterations increased AMF abundances, they did not significantly affect the composition or diversity of AMF communities. In contrast, warming altered the composition of AMF communities and reduced their Shannon–Wiener index and Pielou's evenness. In particular, warming shifted the AMF community composition in favor of Diversisporaceae over Glomeraceae, likely through its impact on soil N and P availability. In addition, AMF communities were phylogenetically random in the unwarmed control but clustered in warming plots, implying more deterministic community assembly under climate warming. Warming enhancement of root growth, N and P availability likely reduced plant C‐allocation to AMF, imposing stronger environmental filtering on AMF communities. We further proposed a conceptual framework that integrates biological and geochemical processes into a mechanistic understanding of warming and precipitation changes’ effects on AMF. Taken together, these results suggest that soil AMF communities may be more sensitive to warming than expected, highlighting the need to monitor their community structure and associated functional consequences on plant communities and soil C dynamics under the future warmer climate.

Natural forests promote phosphorus retention in soil - Zhen Yu; Zhou Guoyi; Lei Liu; Stefano Manzoni; Philippe Ciais; Daniel Goll; Josep Peñuelas; Jordi Sardans; Wantong Wang; Jie Zhu; Lin Li; Junhua Yan; et al. (Global Change Biology, 2022)
Soil phosphorus (P) availability often limits plant productivity. Classical theories suggest that total P content declines at the temporal scale of pedogenesis, and ecosystems develop toward the efficient use of scarce P during succession. However, the trajectory of ecosystem P within shorter time scales of succession remains unclear. We analyzed changes to P pools at the early (I), middle (II), and late (III) stages of growth of plantation forests (PFs) and the successional stages of natural forests (NFs) at 1969 sites in China. We found significantly lower P contents at later growth stages compared to earlier ones in the PF ( p p

8- O - β -D-Glucopyranosyl-2-methylchromone, a new chromone glycoside from the Tibetan medicine plant of Swertia punicea Hemsl - Lin-Yun Mou; Min Wei; Hai-Yan Wu; Li-Jiao Hu; Jian-Long Li; Gan-Peng Li (Natural Product Research, 2022)

Highly selective monoclonal antibody-based lateral flow immunoassay for visual and sensitive determination of conazole fungicides propiconazole in vegetables - Ze-Ke Xu; Jing-Nan Meng; Yi Lei; Xing-Xing Yang; Yi-Yong Yan; Hai-Hong Liu; Hong-Tao Lei; Ting-Cai Wang; Xing Shen; Zhen-Lin Xu (Food Additives & Contaminants: Part A, 2022)

Genome survey sequencing of common vetch (Vicia sativa L.) and genetic diversity analysis of Chinese germplasm with genomic SSR markers - Lin Ma; Xiao Wang; Min Yan; Fang Liu; Shuxing Zhang; Xuemin Wang (Molecular Biology Reports, 2022)
Background Common vetch ( Vicia sativa L.) is an annual legume with excellent suitability in cold and dry regions. Despite its great applied potential, the genomic information regarding common vetch currently remains unavailable. Methods and results In the present study, the whole genome survey of common vetch was performed using the next-generation sequencing (NGS). A total of 79.84 Gbp high quality sequence data were obtained and assembled into 3,754,145 scaffolds with an N50 length of 3556 bp. According to the K-mer analyses, the genome size, heterozygosity rate and GC content of common vetch genome were estimated to be 1568 Mbp, 0.4345 and 35%, respectively. In addition, a total of 76,810 putative simple sequence repeats (SSRs) were identified. Among them, dinucleotide was the most abundant SSR type (44.94%), followed by Tri- (35.82%), Tetra- (13.22%), Penta- (4.47%) and Hexanucleotide (1.54%). Furthermore, a total of 58,175 SSR primer pairs were designed and ten of them were validated in Chinese common vetch. Further analysis showed that Chinese common vetch harbored high genetic diversity and could be clustered into two main subgroups. Conclusion This is the first report about the genome features of common vetch, and the information will help to design whole genome sequencing strategies. The newly identified SSRs in this study provide basic molecular markers for germplasm characterization, genetic diversity and QTL mapping studies for common vetch.

Regulatory role of miR-129 and miR-384-5p on apoptosis induced by oxygen and glucose deprivation in PC12 cell - Hui-Lin Guan; Yue Guan; Wen-Yuan Li; Jia-Wei Liu; Yu-Jia Zheng; Yan-Zhong Guan; Hong-Feng Liu; Li-Xin Guan; Feng-Guo Zhai (Experimental Brain Research, 2022)

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells - Xiang-xing Zhu; Jia-sheng Pan; Tao Lin; Ye-cheng Yang; Qiu-yan Huang; Shuai-peng Yang; Zi-xiao Qu; Zi-sheng Lin; Jian-cong Wen; Ai-fen Yan; Juan Feng; Lian Liu; et al. (Biotechnology Letters, 2022)

Sabulicella rubraurantiaca gen. nov., sp. nov., a new member of the family Acetobacteraceae, isolated from desert soil - Zhi-Liang Lin; Shuai Li; Qi-Chuang Wei; Wen-Hui Lian; Chun-Yan Lu; Lu Xu; Li-Nan Huang; Lei Dong; Wen-Jun Li (Archives of Microbiology, 2022)

Mitogenomes provide new insights into the evolutionary history of Prodiamesinae (Diptera: Chironomidae) - Xiao‐Long Lin; Yan‐Min Zhao; Li‐Ping Yan; Wen‐Bin Liu; Wen‐Jun Bu; Xin‐Hua Wang; Chen‐Guang Zheng (Zoologica Scripta, 2022)
Evolutionary analysis of Prodiamesinae has long been impeded by lack of information, and its phylogenetic relationship with Orthocladiinae remains questionable. Here, ten complete mitochondrial genomes (mitogenomes) of Orthocladiinae sensu lato were newly sequenced, including three Prodiamesinae species and seven Orthocladiinae species. Coupled with published mitogenomes, a total of 12 mitogenomes of Orthocladiinae sensu lato were selected for a comparative mitogenomic analysis and phylogenetic reconstruction. Mitogenomes of Orthocladiinae sensu lato are conserved in structure, and all genes arrange the same gene order as the ancestral insect mitogenome. Nucleotide composition is highly biased, and the control region displayed the highest A + T content. All protein‐coding genes are under purifying selection, and the ATP8 evolves at the fastest rate. In addition, the mitogenomes of Orthocladiinae sensu lato are highly conserved, and they are practically useful for phylogenetic inference, suggesting a re‐classification of Orthocladiinae by sinking Prodiamesinae as a subgroup of Orthocladiinae.

Mutual cheating strengthens a tropical seed dispersal mutualism - Lin Cao; Patrick A. Jansen; Bo Wang; Chuan Yan; Zhenyu Wang; Jin Chen (Ecology, 2022)
While cheating can cause the degradation or collapse of mutualisms, mutualisms may theoretically stabilize or strengthen if the cheating is mutual. Here, we present an asymmetric two‐player game model to explore the evolutionary dynamics of mutual cheating in a mutualistic interaction. We found that the interaction evolved toward mutual cheating if cheating can help both partners obtain higher benefits or if counter‐cheating yields more benefits to victims than simply tolerating exploitation by partners. Then, we present empirical evidence for such mutual cheating strengthening a seed dispersal mutualism in which rodents disperse seeds by scatter hoarding, rodents sabotage seed germination by pruning radicles, and seeds escape rodents by resprouting. By tracking >8,000 Pittosporopsis kerrii seeds throughout the dispersal process in a tropical forest in southwest China, we found that rodents provided better dispersal to seeds that they pruned, i.e., pruned seeds were dispersed farther and were more likely to establish seedlings than unpruned seeds. Compared with unpruned seeds, pruned seeds retained more of their nutrients, i.e., dry mass of pruned seeds was greater than that of unpruned seeds, and were stored for longer by rodents. These findings indicate that mutual cheating benefited both partners. Payoffs estimated from the field experiments indicated that mutual cheating was indeed favored in rodents and plants P. kerrii , and that neither partner was enslaved by the other under mutual cheating. Rather, the mutualism remained stable because the partners were able to exploit each other, and each partner attempted to gain the maximum benefits from the interaction. Our findings indicate that mutual cheating between two mutualists can enhance and stabilize mutualisms.

Mussel Byssal Attachment Weakened by Anthropogenic Noise - Xinguo Zhao; Shuge Sun; Wei Shi; Xuemei Sun; Yan Zhang; Lin Zhu; Qi Sui; Bin Xia; Keming Qu; Bijuan Chen; Guangxu Liu (Frontiers in Marine Science, 2021)
The increasing underwater noise generated by anthropogenic activities has been widely recognized as a significant and pervasive pollution in the marine environment. Marine mussels are a family of sessile bivalves that attach to solid surfaces via the byssal threads. They are widely distributed along worldwide coastal areas and are of great ecological and socio-economic importance. Studies found that anthropogenic noise negatively affected many biological processes and/or functions of marine organisms. However, to date, the potential impacts of anthropogenic noise on mussel byssal attachment remain unknown. Here, the thick shell mussels Mytilus coruscus were exposed to an ambient underwater condition (∼50 dB re 1 μPa) or the playbacks of pile-driving noise (∼70 or ∼100 dB re 1 μPa) for 10 days. Results showed that the noise significantly reduced the secretion of byssal threads (e.g., diameter and volume) and weakened their mechanical performances (e.g., strength, extensibility, breaking stress, toughness and failure location), leading to a 16.95–44.50% decrease in mussel byssal attachment strength. The noise also significantly down-regulated the genes expressions of seven structural proteins (e.g., mfp-1, mfp-2, mfp-3, mfp-6, preCOL-P, preCOL-NG, and preCOL-D) of byssal threads, probably mediating the weakened byssal attachment. Given the essential functions of strong byssal attachment, the findings demonstrate that the increasing underwater anthropogenic noise are posing a great threat to mussel population, mussel-bed community and mussel aquaculture industry. We thus suggest that future work is required to deepen our understanding of the impacts of anthropogenic noise on marine invertebrates, especially these with limited locomotion ability, like bivalves.

Bioactive compounds derived from the marine-derived fungus MCCC3A00951 and their influenza neuraminidase inhibition activity in vitro and in silico - Shun-Zhi Liu; Feng-Ming He; Yan-lin Bin; Chu-Fang Li; Bao-Ying Xie; Xi-Xiang Tang; Ying-Kun Qiu (Natural Product Research, 2021)

Species Composition and Assemblages of Ichthyoplankton in Sansha Bay, Fujian Province, China - Yan Jiang; Bai-an Lin; Hao-yang He; Guang-mao Ding; Li-ting Yan; Ge Zhang; Min Liu; Lian-ming Zheng (Frontiers in Marine Science, 2021)
Sansha Bay (26.40−27.00°N, 119.50−120.20°E) is a typical semi-enclosed bay, located in northern Fujian Province, China, and adjacent to the East China Sea. The ichthyoplankton species composition and assemblage structure were investigated based on monthly sampling at 25 stations in April−September 2019, covering the important spring and summer spawning seasons in the region. Sampling was conducted in the first 3−5 days of the full moon or new moon phases using a standard plankton net through horizontal and vertical tows during daytime. In total, 25,819 ichthyoplankton samples were collected, of which 25,449 samples (i.e., 24,757 eggs and 692 larvae) were from horizontal tows. For horizontal tow samples, the ichthyoplankton were classified into 58 taxa in 15 orders and 23 families with a combination of external morphology and DNA barcoding analyses, from pelagic to demersal and benthic species. The dominant order was the Gobiiformes, including 23 species (39.7% of all species). The dominant taxa, in terms of relative abundance and frequency of occurrence, consisted of commercially important fishes, such as Setipinna tenuifilis (Valenciennes, 1848) (Engraulidae), Epinephelus akaara (Temminck and Schlegel, 1842) (Serraenidae), Collichthys lucidus (Richardson, 1844), Nibea albiflora (Richardson, 1846) (Sciaenidae), Acanthopagrus schlegelii (Bleeker, 1854), and Pagrus major (Temminck and Schlegel, 1843) (Sparidae), accounting for 78.9% of the horizontal tow samples. Low-valued and small-sized fishes, such as Stolephorus commersonnii Lacepède, 1803 (Engraulidae), Solea ovata Richardson, 1846 (Soleidae), Nuchequula nuchalis (Temminck and Schlegel, 1845), and Photopectoralis bindus (Valenciennes, 1835) (Leiognathidae), were also dominant species, accounting for 11.4% of the horizontal tow samples. The ichthyoplankton assemblage was categorized into five different temporal assemblages based on the cluster and nonmetric multidimensional scaling analysis, namely, April, May, June, July, and August−September (ANOSIM, Global R = 0.656, p < 0.01) with the highest density and richness of ichthyoplankton occurred in May. The spatial distribution pattern showed that the high density (ind./m 3 ) of ichthyoplankton occurred mainly in S12–S25 in Guanjingyang and along the Dongchong Peninsula coastline into Dongwuyang, while low density occurred mainly in S01–S11 in the northwest waters of Sandu Island (ANOVA, F = 8.270, p < 0.05). Temperature, salinity, and chlorophyll a were key factors structuring the ichthyoplankton assemblages in Sansha Bay. In addition, this study revealed the changes of the ichthyoplankton composition, density, and spatial distribution in Sansha Bay over the past three decades.

Comparative chloroplast genomes of Prunus subgenus Cerasus (Rosaceae): insights into sequence variations and phylogenetic relationships - Jiawen Yan; Jianhui Li; Lin Yu; Wenfu Bai; Dongling Nie; Ying Xiong; Sizheng Wu (Tree Genetics & Genomes, 2021)

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2021)

Identification and characterization of L-type lectin receptor-like kinases involved in Glycine max–Phytophthora sojae interaction - Mengzhu Zeng; Bowen Wan; Lei Wang; Zhiyuan Chen; Yachun Lin; Wenwu Ye; Yan Wang; Yuanchao Wang (Planta, 2021)

Antibiotic exposure and risk of type 2 diabetes mellitus: a systematic review and meta-analysis - Jielin Zhou; Yan Lin; Yong Liu; Keyang Chen (Environmental Science and Pollution Research, 2021)

Effects of biochar on the growth of Vallisneria natans in surface flow constructed wetland - Chaoqun Zheng; Xuanwen Zhang; Lin Gan; Zhaofang He; Jinling Zhu; Wen Zhang; Yan Gao; Liuyan Yang (Environmental Science and Pollution Research, 2021)

Enhancement of aqueous stability of NH2-MIL-101(Fe) by hydrophobic grafting post-synthetic modification - Jianwei Fu; Lin Wang; Yuheng Chen; Deyi Yan; Huase Ou (Environmental Science and Pollution Research, 2021)

Generation and characterization of a Myh6-driven Cre knockin mouse line - Xinyan Huang; Lei Yan; Shan Kou; Jufeng Meng; Zhengkai Lu; Chao-Po Lin; Chen Liu; Hui Zhang (Transgenic Research, 2021)
Gene deletion by the Cre-Loxp system has facilitated functional studies of many critical genes in mice, offering important insights and allowing deeper understanding on the mechanisms underlying organ development and diseases, such as heart development and diseases. In this study, we generated a Myh6-Cre knockin mouse model by inserting the IRES-Cre-wpre-polyA cassette between the translational stop codon and the 3′ untranslated region of the endogenous Myh6 gene. By crossing knockin mice with the Rosa26 reporter lines, we found that Myh6-Cre targeted cardiomyocytes at the embryonic and postnatal stages. In addition, we were able to inactivate the desmosome gene Desmoplakin (Dsp) by breeding Myh6-Cre mice with a conditional Dsp flox knockout mouse line, which resulted in embryonic lethality during the mid-term pregnancy. These results suggest that the new Myh6-Cre mouse line can serve as a robust tool to dissect the distinct roles of genes involved in heart development and function.

The phosphatidylinositol transfer gene Os08PTS regulating the development and nitrogen metabolism in rice seedling stage - Jingwan Yan; Zhimin Lin; Changquan Hu; Feng Wang (Plant Biotechnology Reports, 2021)

Nitrogen absorption by alpine forage species based on 15N tracer technique in a hydroponic culture - Yan-fang Liu; Wen-ying Wang; Xiao-lin Ma; Pan Liu; Hua-kun Zhou; Zhe Chen; Chong Yang; Jin-hong Guan (Journal of Mountain Science, 2021)

Complete genome sequence of a putative novel ilarvirus isolated from Eleocharis dulcis - Lanqing Lv; Xinyang Wu; Jiajia Weng; Yuchao Lai; Kelei Han; Yuwen Lu; Jiejun Peng; Lin Lin; Shaofei Rao; Guanwei Wu; Jianping Chen; Hongying Zheng; et al. (Archives of Virology, 2021)

Timing and magnitude of climatic extremes differentially elevate mortality but enhance recovery in a fish population - Ming‐Chih Chiu; Shih‐Hsun Chang; Yu‐Ting Yen; Lin‐Yan Liao; Hsing‐Juh Lin (Global Change Biology, 2021)
The countervailing effects of disturbances (e.g., high mortality and enhanced recovery) on population dynamics can occur through demographic processes under rapidly increasing climatic extremes. Across an extreme‐event gradient, we mechanistically demonstrated how dramatic changes in streamflow have affected the population persistence of endangered salmon in monsoonal Taiwan over a three‐decade period. Our modeling indicated that the dynamics of the age‐structured population were attributed to demographic processes, in which extensive mortality was characterized as a function of climatic extremes and vulnerability in the young stage of fish. In the stochastic simulations, we found that the extensive mortality and high proportion of large fish resulted from extreme flooding, which caused high values of postimpact population recovery. Our empirical evidence suggests that the magnitudes and timing of disturbance can explain the population persistence when facing climatic extremes and thereby challenges the understanding of the mechanistic drivers of these countervailing phenomena under changing environmental conditions.

Termite mound formation reduces the abundance and diversity of soil resistomes - Zhen‐Zhen Yan; Qing‐Lin Chen; Chao‐Yu Li; Bao‐Anh Thi Nguyen; Yong‐Guan Zhu; Ji‐Zheng He; Hang‐Wei Hu (Environmental Microbiology, 2021)
Summary Termites are pivotal ecosystem engineers in tropical and subtropical habitats, where they construct massive nests (‘mounds’) that substantially modify soil properties and promote nutrient cycling. Yet, little is known about the roles of termite nesting activity in regulating the spread of antimicrobial resistance (AMR), one of the major Global Health challenges. Here, we conducted a large‐scale (> 1500 km) investigation in northern Australia and found distinct resistome profiles in termite mounds and bulk soils. By profiling a wide spectrum of ARGs, we found that the abundance and diversity of antibiotic resistance genes (ARGs) were significantly lower in termite mounds than in bulk soils ( P P

Precipitation increases the abundance of fungal plant pathogens in Eucalyptus phyllosphere - Qing‐Lin Chen; Hang‐Wei Hu; Zhen‐Zhen Yan; Chao‐Yu Li; Bao‐Anh Thi Nguyen; Yong‐Guan Zhu; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Understanding the current and future distributions of plant pathogens is critical to predict the plant performance and related economic benefits in the changing environment. Yet, little is known about the roles of environmental drivers in shaping the profiles of fungal plant pathogens in phyllosphere, an important habitat of microbiomes on Earth. Here, using a large‐scale investigation of Eucalyptus phyllospheric microbiomes in Australia and the multiple linear regression model, we show that precipitation is the most important predictor of fungal taxonomic diversity and abundance. The abundance of fungal plant pathogens in phyllosphere exhibited a positive linear relationship with precipitation. With this empirical dataset, we constructed current and future atlases of phyllosphere plant pathogens to estimate their spatial distributions under different climate change scenarios. Our atlases indicate that the abundance of fungal plant pathogens would increase especially in the coastal regions with up to 100‐fold increase compared with the current abundance. These findings advance our understanding of the distributions of fungal plant pathogens in phyllospheric microbiomes under the climate change, which can improve our ability to predict and mitigate their impacts on plant productivity and economic losses.

Conservation planning on China's borders with Myanmar, Laos, and Vietnam - Lin Wang; Bin Yang; Yang Bai; Xiaoqiang Lu; Richard T. Corlett; Yunhong Tan; Xiao‐Yong Chen; Jianguo Zhu; Yan Liu; Rui‐Chang Quan (Conservation Biology, 2021)
Transboundary conservation is playing an increasingly important role in maintaining ecosystem integrity and halting biodiversity loss caused by anthropogenic activities. However, lack of information on species distributions in transboundary regions and understanding of the threats in these areas impairs conservation. We developed a spatial conservation plan for the transboundary areas between Yunnan province, southwestern China, and neighboring Myanmar, Laos, and Vietnam in the Indo‐Burma biodiversity hotspot. To identify priority areas for conservation and restoration, we determined species distribution patterns and recent land‐use changes and examined the spatiotemporal dynamics of the connected natural forest, which supports most species. We assessed connectivity with equivalent connected area (ECA), which is the amount of reachable habitat for a species. An ECA incorporates the presence of habitat in a patch and the amount of habitat in other patches within dispersal distance. We analyzed 197,845 locality records from specimen collections and monographs for 21,004 plant and vertebrate species. The region of Yunnan immediately adjacent to the international borders had the highest species richness, with 61% of recorded species and 56% of threatened vertebrates, which suggests high conservation value. Satellite imagery showed the area of natural forest in the border zone declined by 5.2% (13,255 km 2 ) from 1995 to 2018 and monoculture plantations increased 92.4%, shrubland 10.1%, and other cropland 6.2%. The resulting decline in connected natural forest reduced the amount of habitat, especially for forest specialists with limited dispersal abilities. The most severe decline in connectivity was along the Sino‐Vietnamese border. Many priority areas straddle international boundaries, indicating demand and potential for establishing transboundary protected areas. Our results illustrate the importance of bi‐ and multilateral cooperation to protect biodiversity in this region and provide guidance for future conservation planning and practice.

The Rapidly Evolving Fudu Estuary Sandbar Lagoon Landform on the East Coast of the Bohai Sea: Recent Changes and Mechanism - Lianjie Zhang; Jishun Yan; Bo Zhao; Xia Lin; Peng Wang; Chi Zhang; Yonghai Yu; Pan Zhang (Journal of Marine Science and Engineering, 2021)
The Fudu Estuary Sandbar Lagoon is one of the most representative sandbar-lagoon landforms in China, and has undergone drastic evolution in recent years, accompanied by increased coastal engineering activities. The evolution process and its control factors are studied through remote sensing interpretation and coastal sediment transport calculations. During 2010–2021, the sandbar quickly extended at an average speed of 49.5 m/a, but the annual growth has shown a decreasing trend in both area and width, and the shoreline has retreated by 25–45 m. The recent changes are the result of the combined action of natural conditions and human activities. Coastal sediment transport from west to east under the action of W-oriented waves is the natural cause of extension. An estuary dam and artificial island block the sediment transport path, and the material for the new growth of the sandbar comes from the erosion of its west side, which has directly caused the retreat and narrowing of the sandbar. The reduction in sediments from the river further aggravates the shrinkage. It is predicted that the sandbar will continue its eastward extension to connect with the coast in about 2–3 years. The erosion status is unlikely to change before the sediment supply is restored. Measures such as dismantling the estuary dam are recommended.

Euphanoids A and B, two new lathyrane diterpenoids with nitric oxide (NO) inhibitory activity from Euphorbia kansuensis - Xue-Long Yan; Run-Zhu Fan; Jun Sang; Xing-Lin Xie; Gui-Hua Tang; Sheng Yin (Natural Product Research, 2021)

Fouling characteristics of cnidarians (Hydrozoa and Anthozoa) along the coast of China - Tao Yan; Mingqing Lin; Wenhao Cao; Shuaishuai Han; Xikun Song (Journal of Oceanology and Limnology, 2021)

Mesenchymal stem cell-derived exosomes block malignant behaviors of hepatocellular carcinoma stem cells through a lncRNA C5orf66-AS1/microRNA-127-3p/DUSP1/ERK axis - Hao Gu; Chao Yan; Haijun Wan; Lin Wu; Junjie Liu; Zhiqiang Zhu; Dazhi Gao (Human Cell, 2021)

Metabolome and transcriptome profiling of Theobroma cacao provides insights into the molecular basis of pod color variation - Fupeng Li; Baoduo Wu; Lin Yan; Xiaowei Qin; Jianxiong Lai (Journal of Plant Research, 2021)

Aquimarina algicola sp. nov., isolated from the surface of a marine red alga - Xun-Ke Sun; Yan-Lin Zhong; Xu-Yang Chen; Guan-Jun Chen; Zong-Jun Du (Archives of Microbiology, 2021)

Pseudomonas nanhaiensis sp. nov., a lipase-producing bacterium isolated from deep-sea sediment of the South China Sea - Yu Pang; Yage Zhang; Mengru Chen; Wei Lu; Ming Chen; Yongliang Yan; Min Lin; Wei Zhang; Zhengfu Zhou (Antonie van Leeuwenhoek, 2021)

Population, Reproductive and Fishery Dynamics of Spotted Box Crab (Calappa philargius), a New Claw-Only Fishery Species, in the Southern Taiwan Strait, China - Bai-an Lin; Yan Jiang; Robert Boenish; Qing Xu; Min Liu (Frontiers in Marine Science, 2021)
The spotted box crab Calappa philargius (Calappidae) is an increasingly consumed species in China, mainly sourced from a claw-only fishery. Being a not well-characterized species in the literature, this study is warranted to inform sustainable management approaches. Here we report on the first in-depth overview on biology and fishery dynamics of C. philargius in the southern Taiwan Strait of China. Whole body crabs ( N = 1,009) were collected monthly from January to December 2019 from trawlers, operating in the southern Taiwan Strait; sample collection was absent from May to July because of the national fishing moratorium regulation. Sex ratio, growth pattern, size at maturity and fecundity were estimated. The overall male: female ratio was 1: 1.47, significantly differing from the 1: 1 ( p < 0.01); monthly sex ratio variations were also significant ( p < 0.01), suggesting possible seasonal sexual segregation. We found the carapace widths (CW) of males were significantly larger than those of females ( p < 0.01). Based on the occurrence and percentages of berried females, we identified twin spawning events in January–April and August–October with the overall peak occurring in February. Size at 50% female maturity was 11.47 cm CW. Female absolute fecundity was significantly related to CW via a power function relationship ( N = 14, p < 0.01). The estimated average claw yield was 36.28 ± 3.07% of the whole body weight ( N = 95), irrespective of sex and size ( p > 0.5). Capture and trade data of C. philargius using trawl and trap fishing gears were documented to characterize claw-only fishery dynamics for future research and sustainable use.

A new abietane diterpene and anti-complementary constituents from Juniperus tibetica - Dong-Lin Zeng; Chang-Yue Wang; Hui-Qin Gao; Dao-Feng Chen; Yan Lu (Natural Product Research, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Master regulator NtrC controls the utilization of alternative nitrogen sources in Pseudomonas stutzeri A1501 - Zhimin Yang; Qin Li; Yongliang Yan; Xiubin Ke; Yueyue Han; Shaoyu Wu; Fanyang Lv; Yahui Shao; Shanshan Jiang; Min Lin; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2021)
Pseudomonas stutzeri A1501 is a model strain used to study associative nitrogen fixation, and it possesses the nitrogen regulatory NtrC protein in the core genome. Nitrogen sources represent one of the important factors affecting the efficiency of biological nitrogen fixation in the natural environment. However, the regulation of NtrC during nitrogen metabolism in P. stutzeri A1501 has not been clarified. In this work, a phenotypic analysis of the ntrC mutant characterized the roles of NtrC in nitrogen metabolism and the oxidative stress response of P. stutzeri A1501. To systematically identify NtrC-controlled gene expression, RNA-seq was performed to further analyse the gene expression differences between the wild-type strain and the ∆ ntrC mutant under nitrogen fixation conditions. A total of 1431 genes were found to be significantly altered by ntrC deletion, among which 147 associative genes had NtrC-binding sites, and the pathways for nitrogen fixation regulation, nitrogenous compound acquisition and catabolism and nitrate assimilation were discussed. Furthermore, the oxidative stress-related gene ( katB ), which was upregulated by ntrC deletion, was suggested to be a potential target gene of NtrC, thus highlighting the importance of NtrC in nitrogenase protection against oxygen damage. Based on these findings, we propose that NtrC is a high-ranking element in the regulatory network of P. stutzeri A1501 that controls a variety of nitrogen metabolic and oxidative stress responsive traits required for adaptation to complex rhizosphere environments.

Circ_0020093 ameliorates IL-1β-induced apoptosis and extracellular matrix degradation of human chondrocytes by upregulating SPRY1 via targeting miR-23b - Mingli Feng; Lin Jing; Jingbo Cheng; Shuai An; Jiang Huang; Qi Yan (Molecular and Cellular Biochemistry, 2021)
Osteoarthritis (OA) is a chronic disease characterized by articular cartilage degeneration and uncontrolled chondrocyte apoptosis. At present, accumulating evidence introduces that circular RNA (circRNA) is involved in the development of OA. The aim of our study was to explore the role and the functional mechanism of circ_0020093 in OA cell model. Human chondrocytes were treated with interleukin-1 beta (IL-1β) to construct OA model. The expression of circ_0020093, miR-23b, and Sprouty 1 (SPRY1) mRNA was measured by quantitative real-time polymerase chain reaction (qRT-PCR). Cell apoptosis was assessed by flow cytometry assay. The expression of extracellular matrix (ECM)-associated markers and SPRY1 protein level was detected by qRT-PCR and Western blot. Bioinformatics analysis-predicted relationship between miR-23b and circ_0020093 or SPRY1 was further verified by dual-luciferase reporter assay and RNA pull-down assay. In this study, we found that the expression of circ_0020093 and SPRY1 was declined, while miR-23b expression was elevated in IL-1β-treated chondrocytes. IL-1β induced chondrocyte apoptosis and ECM degradation, while these negative effects were alleviated by circ_0020093 overexpression or miR-23b inhibition. MiR-23b was a target of circ_0020093, and SPRY1 was a downstream target of miR-23b. Rescue experiments showed that miR-23b enrichment reversed the role of circ_0020093 overexpression, and SPRY1 knockdown also reversed the effects of miR-23b inhibition. Importantly, circ_0020093 positively regulated SPRY1 expression by targeting miR-23b. In conclusion, circ_0020093 ameliorates IL-1β-induced apoptosis and ECM degradation of human chondrocytes by regulating the miR-23b/SPRY1 axis.

Harvest Time Effects on Yield, Quality and Aroma of Fragrant Rice - Jisheng Zhang; Tianyi Tong; Pouwedeou Mouloumdema Potcho; Lin Li; Suihua Huang; Qinwen Yan; Xiangru Tang (Journal of Plant Growth Regulation, 2021)

Depression Augments Plasma APOA4 without Changes of Plasma Lipids and Glucose in Female Adolescents Carrying G Allele of APOA4 rs5104 - Qi Wei Guo; Yan Jun Si; Yi Lin Shen; Xu Chen; Mei Yang; Ding Zhi Fang; Jia Lin (Journal of Molecular Neuroscience, 2021)

Synthesis of 3D graphene-based materials and their applications for removing dyes and heavy metals - Hefei Sun; Yan Lin; Hagio Takeshi; Xinze Wang; Deyi Wu; Yanqin Tian (Environmental Science and Pollution Research, 2021)

Added value of kilometer-scale modeling over the third pole region: a CORDEX-CPTP pilot study - Xu Zhou; Kun Yang; Lin Ouyang; Yan Wang; Yaozhi Jiang; Xin Li; Deliang Chen; Andreas Prein (Climate Dynamics, 2021)

Shared and specific patterns of structural and functional thalamo-frontal disturbances in manic and euthymic pediatric bipolar disorder - Yi-Bing Guo; Wei-Jia Gao; Zhi-Liang Long; Wei-Fang Cao; Dong Cui; Yong-Xin Guo; Qing Jiao; Jian-Feng Qiu; Lin-Yan Su; Guang-Ming Lu (Brain Imaging and Behavior, 2021)
Bipolar disorder (BD) is clinically defined by alternating depressive and manic episodes with a separated period of euthymia. Thalamo-frontal loop plays vital role in psychotic symptoms, altered motor control and executive difficulties in BD. It remains unclear that structural and functional alterations of thalamo-frontal loop among the different mood states in BD, especially in pediatric BD(PBD). Twenty manic PBD (mPBD), 20 euthymic PBD (ePBD) and 19 healthy controls (HCs) were included in the study. By analyzing the T1 images and fMRI signals, thalamus volume and frontal grey matter cortical thickness were tested, and functional connectivity (FC) between bilateral thalamus and frontal cortex was calculated. Relationship between clinical indices and thalamo-frontal FC was also evaluated in mPBD and ePBD adolescents. Compared to HCs, the cortical thickness of left middle frontal gyrus (MFG), bilateral superior frontal gyrus (SFG) was significantly decreased in both mPBD and ePBD patients, and volume of left thalamus and cortical thickness of right MFG significantly decreased in mPBD patients. Compared to that of the HCs and ePBD subjects, thalamo-frontal hyperconnectivity with MFG was found in mPBD, and compared with that of HCs, thalamo-frontal hypoconnectivity with precentral gyrus/SFG was found in ePBD. In ePBD patients, episode times positively correlated with FC values between thalamus and precentral gyrus. The findings of the present study demonstrate detailed knowledge regarding shared and specific structural and functional disruption in thalamo-frontal loop in mPBD and ePBD subjects. Thalamo-frontal abnormalities reported in adult BD subjects were also observed in adolescent BD patients, and thalamo-frontal dysfunction may be a crucial treatment target in BD.

Degraded polysaccharides from Porphyra haitanensis: purification, physico-chemical properties, antioxidant and immunomodulatory activities - Yun-Feng Huo; Yin-Ting Li; Wei Xia; Chong Wang; Yuan-Yuan Xie; Yan-Bo Wang; Tao Zhou; Ling-Lin Fu (Glycoconjugate Journal, 2021)

Glucose-Responsive Polyelectrolyte Complexes Based on Dendritic Mesoporous Silica for Oral Insulin Delivery - Tingting Qin; Libiao Yan; Xin Wang; Siqi Lin; Qingbing Zeng (AAPS PharmSciTech, 2021)

Consistently positive effect of species diversity on ecosystem, but not population, temporal stability - Qianna Xu; Xian Yang; Ying Yan; Shaopeng Wang; Michel Loreau; Lin Jiang (Ecology Letters, 2021)
Despite much recent progress, our understanding of diversity–stability relationships across different study systems remains incomplete. In particular, recent theory clarified that within‐species population stability and among‐species asynchronous population dynamics combine to determine ecosystem temporal stability, but their relative importance in modulating diversity‐ecosystem temporal stability relationships in different ecosystems remains unclear. We addressed this issue with a meta‐analysis of empirical studies of ecosystem and population temporal stability in relation to species diversity across a range of taxa and ecosystems. We show that ecosystem temporal stability tended to increase with species diversity, regardless of study systems. Increasing diversity promoted asynchrony, which, in turn, contributed to increased ecosystem stability. The positive diversity–ecosystem stability relationship persisted even after accounting for the influences of environmental covariates (e.g., precipitation and nutrient input). By contrast, species diversity tended to reduce population temporal stability in terrestrial systems but increase population temporal stability in aquatic systems, suggesting that asynchronous dynamics among species are essential for stabilizing diverse terrestrial ecosystems. We conclude that there is compelling empirical evidence for a general positive relationship between species diversity and ecosystem‐level temporal stability, but the contrasting diversity–population temporal stability relationships between terrestrial and aquatic systems call for more investigations into their underlying mechanisms.

Quercetin Attenuates High-Fat Diet-Induced Excessive Fat Deposition of Spotted Seabass (Lateolabrax maculatus) Through the Regulatory for Mitochondria and Endoplasmic Reticulum - Yan-Zou Dong; Tian Xia; Ji-Bin Lin; Ling Wang; Kai Song; Chun-Xiao Zhang (Frontiers in Marine Science, 2021)
This study aimed to investigate the effects of quercetin (QUE) on fat deposition and the underlying mechanism. Fish were fed four test diets: normal fat diet (NFD), high-fat diet (HFD), and HFD supplemented with 0.5 or 1.0 g/kg quercetin (QUE0.5 or QUE1.0). The results showed that HFD feeding resulted in poor growth and feed utilization while QUE treatment reversed this. The fat contents of serum and liver were increased by HFD and QUE supplementation significantly decreased fat content. Furthermore, gene expressions and ultrastructure observation showed that mitochondrial biogenesis and mitophagy were inhibited and endoplasmic reticulum stress (ERS) in the HFD group. QUE can activate the biogenesis and autophagy of mitochondria and suppress ERS, which is related to its fat-lowering effect.

Numerical Investigation of the Characteristics of Erosion in a Centrifugal Pump for Transporting Dilute Particle-Laden Flows - Rui-Jie Zhao; You-Long Zhao; De-Sheng Zhang; Yan Li; Lin-Lin Geng (Journal of Marine Science and Engineering, 2021)
Erosion in centrifugal pumps for transporting flows with dilute particles is a main pump failure problem in many engineering processes. A numerical model combining the computational fluid dynamics (CFD) and Discrete Element Method (DEM) is applied to simulate erosion in a centrifugal pump. Different models of the liquid-solid inter-phase forces are implemented, and the particle-turbulence interaction is also defined. The inertial particles considered in this work are monodisperse and have finite size. The numerical results are validated by comparing the results with a series of experimental data. Then, the effects of particle volume fraction, size, and shape on the pump erosion are estimated in the simulations. The results demonstrate that severe erosive areas are located near the inlet and outlet of the pressure side of the impeller blade, the middle region of the blade, the corners of the shroud and hub of the impeller adjoining to the pressure side of the blade, and the volute near the pump tongue. Among these locations, the maximum erosion occurs near the inlet of the pressure side of the blade. Erosion mitigation occurs under the situation where more particles accumulate in the near-wall region of the eroded surface, forming a buffering layer. The relationship between the particle size and the erosion is nonlinear, and the 1 mm particle causes the maximum pump erosion. The sharp particles cause more severe erosion in the pump because both the frequency of particle-wall collisions and the impact angle increase with the increasing sharpness of the particle.

In silico design of antimicrobial oligopeptides based on 3D-QSAR modeling and bioassay evaluation - Guangping Li; Yuxuan Wang; Yan Shen; Haiqiong Guo; Qingxiu He; Yong Hu; Haibin Liu; Zhihua Lin; Yuanqiang Wang (Medicinal Chemistry Research, 2021)

Opposite response of maize ZmCCT to photoperiod due to transposon jumping - Shuyang Zhong; Hangqin Liu; Yan Li; Zhongwei Lin (Theoretical and Applied Genetics, 2021)

Climate change impacts on China’s marine ecosystems - Bin Kang; Gretta T. Pecl; Longshan Lin; Peng Sun; Peidong Zhang; Yuan Li; Linlin Zhao; Xin Peng; Yunrong Yan; Chunyan Shen; Wentao Niu (Reviews in Fish Biology and Fisheries, 2021)

Magnetic Resonance Imaging-Guided and Navigated Individualized Repetitive Transcranial Magnetic Stimulation for Cognitive Impairment in Schizophrenia - Xu-Sha Wu; Tian-Cai Yan; Xian-Yang Wang; Yang Cao; Xiao-Fan Liu; Yu-Fei Fu; Lin Wu; Yin-Chuan Jin; Hong Yin; Long-Biao Cui (Neuroscience Bulletin, 2021)

Descending Modulation of Spinal Itch Transmission by Primary Somatosensory Cortex - Zi-Han Wu; Han-Yu Shao; Yuan-Yuan Fu; Xiao-Bo Wu; De-Li Cao; Sheng-Xiang Yan; Wei-Lin Sha; Yong-Jing Gao; Zhi-Jun Zhang (Neuroscience Bulletin, 2021)

Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson’s disease: a systematic review and meta-analysis - De-Qi Jiang; Qing-Min Zang; Li-Lin Jiang; Yan Wang; Ming-Xing Li; Jing-Yi Qiao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Identifying rainfall threshold of flash flood using entropy decision approach and hydrological model method - Kairong Lin; Jiaqi Zhou; Ruhao Liang; Xiaozhang Hu; Tian Lan; Meixian Liu; Xin Gao; Denghua Yan (Natural Hazards, 2021)