Effect of Quicklime on Microbial Community in Strong Acidic Soil - Junwei Liang; Xiangquan Yu; Yafan Cao; Jiguang Zhang; Ning Yan; Lin Xue; Xianjie Cai; Guoming Shen (Journal of Soil Science and Plant Nutrition, 2021)

Differential DNA Methylation Profiles in Patients with Temporal Lobe Epilepsy and Hippocampal Sclerosis ILAE Type I - Wang Zhang; Haiyang Wang; Binchao Liu; Miaomiao Jiang; Yifei Gu; Shi Yan; Xian Han; Alicia Y. Hou; Chongyang Tang; Zhenfeng Jiang; Hong Shen; Meng Na; et al. (Journal of Molecular Neuroscience, 2021)

Applying Artificial Intelligence (AI) Techniques to Implement a Practical Smart Cage Aquaculture Management System - Chung-Cheng Chang; Jung-Hua Wang; Jenq-Lang Wu; Yi-Zeng Hsieh; Tzong-Dar Wu; Shyi-Chy Cheng; Chin-Chun Chang; Jih-Gau Juang; Chyng-Hwa Liou; Te-Hua Hsu; Yii-Shing Huang; Cheng-Ting Huang; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose This paper presents our team’s results to establish an AIoT smart cage culture management system. Methods According to the built system, the farmed field information is transmitted to the data platform of Ocean Cloud, and all collected data and analysis results can be applied to the cage culture field after the bigdata analysis. Results This management system successfully integrates AI and IoT technologies and is applied in cage culture. Using underwater biological analysis images and AI feeding as examples, this paper explains how the system integrates AI and IoT into a feasible framework that can constantly acquire information about the health status of fish, survival rate of fish, as well as the feed residuals. Conclusion The results of our research enable the aquaculture operators or owners to efficiently reduce the feed residual, monitor the growth of fish, and increase fish survival rate, thereby increasing the feed conversion rate.

Passivation and remediation of Pb and Cr in contaminated soil by sewage sludge biochar tubule - Lin Chen; Qi Ni; Yan Wu; Chuan Fu; Wei Ping; Hongyu Bai; Mengnan Li; Hongcheng Huang; Hanshuang Liu (Environmental Science and Pollution Research, 2021)

Protective effect of Bombyx mori gloverin on intestinal epithelial cells exposure to enterotoxigenic E. coli - Qian Lin; Qingqing Fu; Guoqi Su; Daiwen Chen; Bing Yu; Yuheng Luo; Ping Zheng; Xiangbing Mao; Zhiqing Huang; Jie Yu; Junqiu Luo; Hui Yan; et al. (Brazilian Journal of Microbiology, 2021)

Application of the modified cytosine base-editing in the cultured cells of bama minipig - Jia-sheng Pan; Zi-sheng Lin; Jian-cong Wen; Jian-feng Guo; Xia-hui Wu; Ying-ying Liu; Wen-jun Lai; Qi-ying Liang; Yong-shi Xie; Yi-rou Chen; Yi-hong Chen; Ai-fen Yan; et al. (Biotechnology Letters, 2021)

Neuroanatomical correlates of self-awareness of highly practiced visuomotor skills - Junjun Li; Zhenglong Lin; Ran Tao; Min Xu; Shihong Kong; Hong-Yan Bi; Yang Yang (Brain Structure and Function, 2021)

Interaction between the cell walls of microalgal host and fungal carbohydrate‐activate enzymes is essential for the pathogenic parasitism process - Juan Lin; Hailong Yan; Liang Zhao; Yanhua Li; Bahareh Nahidian; Mianmian Zhu; Qiang Hu; Danxiang Han (Environmental Microbiology, 2021)
Summary Fungi can parasitize microalgae, exerting profound impacts on both the aquatic ecosystems and microalgal mass cultures. In this study, the unicellular green alga Haematococcus pluvialis and the blastocladialean fungus Paraphysoderma sedebokerense were used as a model system to address the mechanisms underlying the fungal parasitism on the algal host. High‐throughput metabolic assay indicated that P . sedebokerense can utilize several carbon sources with a preference for mannose, glucose and their oligosaccharides, which was compatible with the profile of the host algal cell walls enriched with glucan and mannan. The results of dual transcriptomics analysis suggested that P . sedebokerense can upregulate a large number of putative carbohydrate‐activate enzymes (CAZymes) encoding genes, including those coding for the endo‐1,4‐β‐glucanase and endo‐1,4‐β‐mannanase during the infection process. The cell walls of H . pluvialis can be decomposed by both P . sedebokerense and commercial CAZymes (e.g. cellulase and endo‐1,4‐β‐mannanase) to produce mannooligomers, while several putative parasitism‐related genes of P . sedebokerense can be in turn upregulated by mannooligomers. In addition, the parasitism can be blocked by interfering the selected CAZymes including glucanase, mannanase and lysozyme with the specific inhibitors, which provided a framework for screening suitable compounds for pathogen mitigation in algal mass culture.

Assessment of the Nutritional Value of Cultured Sea Cucumber Apostichopus japonicus - Meng Li; Yue Gao; Yan-xia Qi; Zhi-yuan Song; Zhi-bo Li; Yan-tong Lin; Qian-cheng Zhao (Journal of Aquatic Food Product Technology, 2021)

Optimization of ultrasound and microwave-assisted extraction of sweet cherry tree branches and chemical component analysis by UPLC–MS/MS - Huimin Zhang; Hongguang Yan; Cuixiang Lu; Hui Lin; Quan Li (Trees, 2021)

Wogonin Accelerates Hematoma Clearance and Improves Neurological Outcome via the PPAR-γ Pathway After Intracerebral Hemorrhage - Jianfeng Zhuang; Yucong Peng; Chi Gu; Huihui Chen; Zheng Lin; Hang Zhou; Xiao Wu; Jianru Li; Xiaobo Yu; Yang Cao; Hanhai Zeng; Xiongjie Fu; et al. (Translational Stroke Research, 2021)

Evaluation and improvement of the greenness of plasma spraying through life cycle assessment and grey relational analysis - Jing Liu; Liming Wang; Fangyi Li; Yanle Li; Xueju Ran; Lin Kong; Yan Fu (The International Journal of Life Cycle Assessment, 2021)

Cardiac Adipose Tissue Contributes to Cardiac Repair: a Review - Yan Lin; Siyin Ding; Yuwen Chen; Meixiang Xiang; Yao Xie (Stem Cell Reviews and Reports, 2021)

The relationship between anthocyanin accumulation and photoprotection in young leaves of two dominant tree species in subtropical forests in different seasons - Zheng-Chao Yu; Wei Lin; Xiao-Ting Zheng; Wah Soon Chow; Yan-Na Luo; Min-Ling Cai; Chang-Lian Peng (Photosynthesis Research, 2021)

Associations of Sleep Characteristics with Cerebrospinal Fluid sTREM2 in Cognitively Normal Older Adults: the CABLE Study - He-Ying Hu; Ling-Zhi Ma; Hao Hu; Yan-Lin Bi; Ya-Hui Ma; Xue-Ning Shen; Ya-Nan Ou; Qiang Dong; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

Genipin Attenuates Tau Phosphorylation and Aβ Levels in Cellular Models of Alzheimer’s Disease - Meiting Li; Nan Cai; Liang Gu; Lijun Yao; Decheng Bi; Weishan Fang; Zhijian Lin; Yan Wu; Hong Xu; Hui Li; Zhangli Hu; Xu Xu (Molecular Neurobiology, 2021)

Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2 - Yan Wen; Zihao Su; Ziwu Wang; Lin Yang; Guoping Liu; Zicong Shang; Yangyang Duan; Heng Du; Zhenmeiyu Li; Yan You; Xiaosu Li; Zhengang Yang; et al. (Molecular Neurobiology, 2021)

Pest control ability, technical guidance, and pesticide overuse: evidence from rice farmers in rural China - Yanzhong Huang; Xiaofeng Luo; Di Liu; Sanxia Du; Aqian Yan; Lin Tang (Environmental Science and Pollution Research, 2021)

Association between population density and infection rate suggests the importance of social distancing and travel restriction in reducing the COVID-19 pandemic - Heliang Yin; Tong Sun; Lan Yao; Yan Jiao; Li Ma; Lin Lin; J Carolyn Graff; Lotfi Aleya; Arnold Postlethwaite; Weikuan Gu; Hong Chen (Environmental Science and Pollution Research, 2021)

Mild encephalitis/encephalopathy with a reversible splenial lesion associated with respiratory syncytial virus infection in infants - Xue-Lin Li; Jinming Han; Zhong-Rui Yan; Bing-Wei Zhang; Hai-Yang Wang (Journal of NeuroVirology, 2021)

Numerical Investigation to the Effect of Suction-Induced Seepage on the Settlement in the Underwater Vacuum Preloading with Prefabricated Vertical Drains - Shu Lin; Dengfeng Fu; Zefeng Zhou; Yue Yan; Shuwang Yan (Journal of Marine Science and Engineering, 2021)
Vacuum preloading combined with prefabricated vertical drains (PVDs) has the potential to improve the soft sediments under water, however, its development is partly limited by the unclear understanding of the mechanism. This paper aims to extend the comprehension of the influential mechanism of overlapping water in the scenario of underwater vacuum preloading with PVDs. The systematic investigations were conducted by small strain finite element drained analyses, with the separated analysis schemes considering suction-induced consolidation, seepage and their combination. The development of settlement in the improved soil region and the evolution of seepage flow from the overlapping water through the non-improved soil region into improved zone are examined in terms of the build-up of excess pore pressure. Based on the results of numerical analyses, a theoretical approach was set out. It was capable to estimate the time-dependent non-uniform settlement along the improved soil surface in response to the combined effects of suction-induced consolidation and seepage. The difference of underwater and onshore vacuum preloading with PVDs is discussed with some practical implication and suggestion provided.

Mid-Level Riverine Outflow Matters: A Case of Microplastic Transport in the Jiulong River, China - Yifan Li; Siguang Liu; Mengyang Liu; Wei Huang; Kai Chen; Yongcheng Ding; Fangzhu Wu; Hongwei Ke; Linghao Lou; Yan Lin; Mingyu Zhang; Fengjiao Liu; et al. (Frontiers in Marine Science, 2021)
Riverine outflow is one of the major pathways for microplastic transportation to coastal environments. Research on the output of microplastics in small- or medium-sized rivers will help accurately understand the status of their marine loads. In this study, we used both trawling and pumping methods to collect microplastics of different sizes in the Jiulong River Estuary and Xiamen Bay. We found that the abundance of small microplastics (44 μm–5.0 mm) was at least 20 times higher than the large particles (0.33–5.0 mm). The abundance of the large particles ranges from 4.96 to 16.3 particles/m 3 , and that of the small particles ranged from 82.8 to 918 particles/m 3 . Granule was the dominant shape (>60%), and polyethylene (PE), polypropylene (PP), and polyethylene terephthalate (PET) were the most common components. The riverine flux of small microplastics (44 μm–5 mm, 472 ± 230 t/y) was at a medium level and was eight times greater than that of large particles (0.33–5.0 mm, 61.2 ± 2.6 t/y). The behavior of the large microplastics was relatively conservative, whose abundance had a significant correlation with salinity ( R 2 = 0.927) and was mainly influenced by physical factors. In contrast, results of statistical analysis revealed that more complicated factors influenced the small microplastics.

Plant-derived antioxidants incorporated into active packaging intended for vegetables and fatty animal products: a review - Yan Zhang; Baoying Wang; Fangfang Lu; Lin Wang; Yanhong Ding; Xinya Kang (Food Additives & Contaminants: Part A, 2021)

Capacity of transportation and spread of COVID-19—an ironical fact for developed countries - Li Ma; Zhuo Yu; Yan Jiao; Lin Lin; Wei Zhong; Sara W. Day; Arnold Postlethwaite; Hong Chen; Qiang Li; Heliang Yin; Gang Wang (Environmental Science and Pollution Research, 2021)

Selective retention of particulate matter by nine plant species in central Shanxi Province, China - Lishuai Xu; Qian Yan; Yongchong Lin; Zhilei Zhen; Liwen Liu; Yonghong Duan (Environmental Science and Pollution Research, 2021)

Do air pollutants as well as meteorological factors impact Corona Virus Disease 2019 (COVID-19)? Evidence from China based on the geographical perspective - Lin Pei; Xiaoxia Wang; Bin Guo; Hongjun Guo; Yan Yu (Environmental Science and Pollution Research, 2021)

Identification of three seagrass species in coral reef ecosystem by using multiple genes of DNA barcoding - Xiancheng Lin; Junde Dong; Qingsong Yang; Weiguo Zhou; Yan Wang; Ying Zhang; Manzoor Ahmad; Yingting Sun; Youshao Wang; Juan Ling (Ecotoxicology, 2021)

Assessment of ecological importance of the Qinghai-Tibet Plateau based on ecosystem service flows - Zi-yan Lin; Yi Xiao; Zhi-yun Ouyang (Journal of Mountain Science, 2021)

Effects of mutual grafting Solanum photeinocarpum from two ecosystems on physiology and selenium absorption of their offspring under selenium stress - Kewen Huang; Yan Wang; Xiaohan Wei; Yuhui Bie; Huixuan Zhou; Lili Deng; Lijin Lin; Ming’an Liao (Acta Physiologiae Plantarum, 2021)

A survey of chloramphenicol residues in aquatic products of Shenzhen, South China - Lan Luo; Shaoyou Lu; Chengpeng Huang; Fu Wang; Yan Ren; He Cao; Qihui Lin; Zhiqiang Tan; Xiaodong Wen (Food Additives & Contaminants: Part A, 2021)

Secondary Structural Transformation of Bovine Lactoferricin Affects Its Antibacterial Activity - Jie Pei; Lin Xiong; Pengjia Bao; Min Chu; Ping Yan; Xian Guo (Probiotics and Antimicrobial Proteins, 2021)

Sleep Characteristics and Cerebrospinal Fluid Progranulin in Older Adults: The CABLE Study - Meng Wang; Fu-Rong Sun; Yan-Lin Bi; Ya-Hui Ma; Jian-Jun Yin; Xue-Ning Shen; Xiao-Tong Wang; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

Experimental Research on Adsorption Kinetic Characteristics of CH4, CO2, and N2 in Coal from Junggar Basin, China, at Different Temperatures - Wanjie Sun; Haifei Lin; Shugang Li; Xiangguo Kong; Hang Long; Min Yan; Yang Bai; Jiamin Tian (Natural Resources Research, 2021)

Serum macrophage migration inhibitory factor as a potential biomarker to evaluate therapeutic response in patients with allergic asthma: an exploratory study - Huiyuan Zhu; Shaochun Yan; Jingshuo Wu; Zhong Zhang; Xiaolin Li; Zheng Liu; Xing Ma; Lina Zhou; Lin Zhang; Mingming Feng; Yiwei Geng; Aixin Zhang; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Precise Control and Experimental Evaluation of a Novel Endoscopic Suturing Device for Large Perforations - Liaoyuan Ai; Chengli Song; Shuchen Ge; Shiju Yan; Lin Mao; Alfred Cuschieri (Journal of Medical and Biological Engineering, 2021)

Luteolin alleviates ulcerative colitis through SHP-1/STAT3 pathway - Bo-Lin Li; Dan-Yang Zhao; Peng-Li Du; Xiao-Tian Wang; Qian Yang; Yan-Ru Cai (Inflammation Research, 2021)

Water Inrush Risk Assessment of Coal Floor After CBM Development Based on the Fractal-AHP-Vulnerlability Index Method - Jian-lin Li; Shu-wei Wang; Yan Wang; Xin-yi Wang; Xiong-xiong Wang (Geotechnical and Geological Engineering, 2021)

Safety and efficacy of new oral anticoagulants compared to those of warfarin in AF patients with cancer: a meta-analysis of randomized clinical trials and observational studies - Yueming Chen; Min Mao; Jing Chang; Jing Yan; Tiantian Yang; Yang Liu; Meng Luo; Yuhao Hu; Qi Yang; Lin Zhou; Kanghua Ma (European Journal of Clinical Pharmacology, 2021)

Enhanced treatment of shale gas fracturing waste fluid through plant-microbial synergism - Bo Shao; Xu Tan; Ju-Long Li; Mei He; Lei Tian; Wen-Jie Chen; Yan Lin (Environmental Science and Pollution Research, 2021)

Effects of multi-phase inoculation on the fungal community related with the improvement of medicinal herbal residues composting - Xiao-Lin Lu; Hao Wu; Shi-Li Song; Hong-Yan Bai; Meng-Jun Tang; Fang-Ji Xu; Yan Ma; Chuan-Chao Dai; Yong Jia (Environmental Science and Pollution Research, 2021)

Alterinioella nitratireducens gen. nov., sp. nov., Isolated from Seawater in the West Pacific Ocean - Yan-Hui Kong; Cong Sun; Li-Li Guo; Lin Xu; Yue-Hong Wu; Xue-Wei Xu (Current Microbiology, 2021)

Icaritin Inhibits Skin Fibrosis through Regulating AMPK and Wnt/β-catenin Signaling - Ming Li; Qingmei Liu; Shan He; Xiangzhen Kong; Jinpei Lin; Yan Huang; Wenyu Wu; Jinfeng Wu (Cell Biochemistry and Biophysics, 2021)

Nanoselenium and Selenium Yeast Have Minimal Differences on Egg Production and Se Deposition in Laying Hens - Tian-Tian Meng; Xue Lin; Chun-Yan Xie; Jian-Hua He; Yang-Kui Xiang; Yi-Qiang Huang; Xin Wu (Biological Trace Element Research, 2021)

Genome-wide identification of GMP genes in Rosaceae and functional characterization of FaGMP4 in strawberry (Fragaria × ananassa) - Yuanxiu Lin; Jiahao Zhang; Lintai Wu; Yunting Zhang; Qing Chen; Mengyao Li; Yong Zhang; Ya Luo; Yan Wang; Xiaorong Wang; Haoru Tang (Genes & Genomics, 2021)

Ghrelin Affects Gastric Cancer Progression by Activating AMPK Signaling Pathway - Xiao-Lin Hu; Yong-Jun Zhu; Chang-Hua Hu; Li You; Juan Wu; Xiao-Yan He; Wen-Jie Huang; Zong-Hui Wu (Biochemical Genetics, 2021)

Potential benefits of liming to acid soils on climate change mitigation and food security - Yan Wang; Zhisheng Yao; Yang Zhan; Xunhua Zheng; Minghua Zhou; Guangxuan Yan; Lin Wang; Christian Werner; Klaus Butterbach‐Bahl (Global Change Biology, 2021)
Globally, about 50% of all arable soils are classified as acidic. As crop and plant growth are significantly hampered under acidic soil conditions, many farmers, but increasingly as well forest managers, apply lime to raise the soil pH. Besides its direct effect on soil pH, liming also affects soil C and nutrient cycles and associated greenhouse gas (GHG) fluxes. In this meta‐analysis, we reviewed 1570 observations reported in 121 field‐based studies worldwide, to assess liming effects on soil GHG fluxes and plant productivity. We found that liming significantly increases crop yield by 36.3%. Also, soil organic C (SOC) stocks were found to increase by 4.51% annually, though soil respiration is stimulated too (7.57%). Moreover, liming was found to reduce soil N 2 O emission by 21.3%, yield‐scaled N 2 O emission by 21.5%, and CH 4 emission and yield‐scaled CH 4 emission from rice paddies by 19.0% and 12.4%, respectively. Assuming that all acid agricultural soils are limed periodically, liming results in a total GHG balance benefit of 633−749 Tg CO 2 ‐eq year −1 due to reductions in soil N 2 O emissions (0.60−0.67 Tg N 2 O‐N year −1 ) and paddy soil CH 4 emissions (1.75−2.21 Tg CH 4 year −1 ) and increases in SOC stocks (65.7–110 Tg C year −1 ). However, this comes at the cost of an additional CO 2 release (c. 624–656 Tg CO 2 year −1 ) deriving from lime mining, transport and application, and lime dissolution, so that the overall GHG balance is likely neutral. Nevertheless, liming of acid agricultural soils will increase yields by at least 6.64 × 10 8 Mg year −1 , covering the food supply of 876 million people. Overall, our study shows for the first time that a general strategy of liming of acid agricultural soils is likely to result in an increasing sustainability of global agricultural production, indicating the potential benefit of liming acid soils for climate change mitigation and food security.

QTL mapping of the genetic basis of stem diameter in soybean - Chong-Yuan Sun; Yu-Ming Yang; Lin Jia; Xiao-Qian Liu; Huan-Qing Xu; Hai-Yan Lv; Zhong-Wen Huang; Dan Zhang (Planta, 2021)

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

New insights into the fine-scale history of western–eastern admixture of the northwestern Chinese population in the Hexi Corridor via genome-wide genetic legacy - Hongbin Yao; Mengge Wang; Xing Zou; Yingxiang Li; Xiaomin Yang; Ailin Li; Hui-Yuan Yeh; Peixin Wang; Zheng Wang; Jingya Bai; Jianxin Guo; Jinwen Chen; et al. (Molecular Genetics and Genomics, 2021)

The hand-arm vibration syndrome associated with the grinding of handheld workpieces in a subtropical environment - Nuoyan Wei; Hansheng Lin; Ting Chen; Bin Xiao; Maosheng Yan; Li Lang; Hongyu Yang; Shan Wu; Paul-Émile Boileau; Qingsong Chen (International Archives of Occupational and Environmental Health, 2021)

Acute Exposure of Atmospheric Ultrafine Particles Induced Inflammation Response and Dysregulated TGFβ/Smads Signaling Pathway in ApoE−/− Mice - Kang Li; Jun Yan; Shumei Wang; Xiaotian Liang; Bencheng Lin; Lei Tian; Huanliang Liu; Xiaohua Liu; Zhuge Xi (Cardiovascular Toxicology, 2021)

Effects of Fish Oil Combined with Selenium and Zinc on Learning and Memory Impairment in Aging Mice and Amyloid Precursor Protein Processing - Chao-xu Fu; Lin Dai; Xiu-yuan Yuan; Yan-ji Xu (Biological Trace Element Research, 2021)

Construction of an infectious full-length cDNA clone of potato aucuba mosaic virus - Buyang Chen; Qi Lin; Yueyan Yin; Liangliang Jiang; Fang Wang; Shuzhen Hu; Xinyang Wu; Fei Xu; Jiejun Peng; Hongying Zheng; Chengqi Yan; Xiaohan Mo; et al. (Archives of Virology, 2021)

Complete genome sequence of passiflora virus Y infecting passion fruit in China - Binghua Chen; Dali Wu; Hongying Zheng; Guangze Li; Yuhao Cao; Jianping Chen; Fei Yan; Xuemei Song; Lin Lin (Archives of Virology, 2021)

Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling - Size Li; Yiqun Yu; Xiaolan Bian; Li Yao; Min Li; Yan-Ru Lou; Jing Yuan; Hai-shu Lin; Lucy Liu; Bing Han; Xiaoqiang Xiang (Archives of Toxicology, 2021)

Study on characteristics of waterflooding in fractured reservoirs based on discrete fracture model - Fanle Meng; Junjian Li; Hanqiao Jiang; Lin Zhao; Linkai Li; Yan Qiao; Yu Zhou; Fei Xu (Arabian Journal of Geosciences, 2021)

Preliminary calibration results of the HY-2B altimeter’s SSH at China’s Wanshan calibration site - Chuntao Chen; Jianhua Zhu; Chaofei Ma; Mingsen Lin; Longhao Yan; Xiaoqi Huang; Wanlin Zhai; Bo Mu; Yongjun Jia (Acta Oceanologica Sinica, 2021)

Termite mounds reduce soil microbial diversity by filtering rare microbial taxa - Qing‐Lin Chen; Hang‐Wei Hu; Zhen‐Zhen Yan; Chao‐Yu Li; Bao‐Anh Thi Nguyen; Yong Zheng; Yong‐Guan Zhu; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Termites are ubiquitous insects in tropical and subtropical habitats, and some of them construct massive nests (‘mounds’), which substantially promote substrate heterogeneity by altering soil properties. Yet, the role of termite nesting process in regulating the distribution and diversity of soil microbial communities remains poorly understood, which introduces uncertainty in predictions of ecosystem functions of termite mounds in a changing environment. Here, by using amplicon sequencing, we conducted a survey of 134 termite mounds across >1500 km in northern Australia and found that termite mounds significantly differed from bulk soils in the microbial diversity and community compositions. Compared with bulk soils, termite nesting process decreased the microbial diversity and the relative abundance of rare taxa. Rare taxa had a narrower habitat niche breadth than dominant taxa and might be easier to be filtered by the potential intensive microbial competition during the nesting processes. We further demonstrated that the shift in pH induced by termite nesting process was a major driver shaping the microbial community profiles in termite mounds. Together, our work provides novel evidence that termite nesting is an important process in regulating soil microbial diversity, which advances our understanding of the functioning of termite mounds.

Two new 8-isopentenyl isoflavane derivatives from Astragalus dolichochaete diels - Ding-Wei Wang; Chao-Jiang Xiao; Lin Qiu; Xin-Yan Tian; Xiang Dong; Bei Jiang (Natural Product Research, 2021)

Effects of Climate Change in Marine Ecosystems Based on the Spatiotemporal Age Structure of Top Predators: A Case Study of Bigeye Tuna in the Pacific Ocean - Kuo-Wei Lan; Yan-Lun Wu; Lu-Chi Chen; Muhamad Naimullah; Tzu-Hsiang Lin (Frontiers in Marine Science, 2021)
How top predators behave and are distributed depend on the conditions in their marine ecosystem through bottom−up forcing; this is because where and when these predators can feed and spawn are limited and change often. This study investigated how the catch rates of immature and mature cohorts of bigeye tuna (BET) varied across space and time; this was achieved by analyzing data on the Taiwanese longline fishery in the western and central Pacific Ocean (WCPO). We also conducted a case study on the time series patterns of BET cohorts to explore the processes that underlie the bottom-up control of the pelagic ecosystem that are influenced by decadal climate events. Wavelet analysis results revealed crucial synchronous shifts in the connection between the pelagic ecosystems at low trophic levels in relation to the immature BET cohort. Many variables exhibited decreasing trends after 2004–2005, and we followed the Pacific Decadal Oscillation (PDO) as a bottom-up control regulator. The results indicated that low recruitment into the mature cohort occurs 3 years after a decrease in the immature cohort’s food stocks, as indicated by a 3-year lag in our results. This finding demonstrated that, by exploring the connection between low-trophic-level species and top predators at various life stages, we can better understand how climate change affects the distribution and abundance of predator fish.

Structure of SARS-CoV-2 main protease in the apo state - Xuelan Zhou; Fanglin Zhong; Cheng Lin; Xiaohui Hu; Yan Zhang; Bing Xiong; Xiushan Yin; Jinheng Fu; Wei He; Jingjing Duan; Yang Fu; Huan Zhou; et al. (Science China Life Sciences, 2021)

Human β-Defensin 118 Attenuates Escherichia coli K88–Induced Inflammation and Intestinal Injury in Mice - Qian Lin; Qingqing Fu; Xiang Li; Yuheng Luo; Junqiu Luo; Daiwen Chen; Xiangbing Mao; Bing Yu; Ping Zheng; Zhiqing Huang; Jie Yu; Hui Yan; et al. (Probiotics and Antimicrobial Proteins, 2021)

Decoding Cortical Glial Cell Development - Xiaosu Li; Guoping Liu; Lin Yang; Zhenmeiyu Li; Zhuangzhi Zhang; Zhejun Xu; Yuqun Cai; Heng Du; Zihao Su; Ziwu Wang; Yangyang Duan; Haotian Chen; et al. (Neuroscience Bulletin, 2021)
Mouse cortical radial glial cells (RGCs) are primary neural stem cells that give rise to cortical oligodendrocytes, astrocytes, and olfactory bulb (OB) GABAergic interneurons in late embryogenesis. There are fundamental gaps in understanding how these diverse cell subtypes are generated. Here, by combining single-cell RNA-Seq with intersectional lineage analyses, we show that beginning at around E16.5, neocortical RGCs start to generate ASCL1 + EGFR + apical multipotent intermediate progenitors (MIPCs), which then differentiate into basal MIPCs that express ASCL1, EGFR, OLIG2, and MKI67. These basal MIPCs undergo several rounds of divisions to generate most of the cortical oligodendrocytes and astrocytes and a subpopulation of OB interneurons. Finally, single-cell ATAC-Seq supported our model for the genetic logic underlying the specification and differentiation of cortical glial cells and OB interneurons. Taken together, this work reveals the process of cortical radial glial cell lineage progression and the developmental origins of cortical astrocytes and oligodendrocytes.

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

Activating Transcription Factor 6 Contributes to Functional Recovery After Spinal Cord Injury in Adult Zebrafish - Zhe Ji; Zhi-Lan Zhou; Qin Hao; Lin Zhao; Chun Cui; Shu-Bing Huang; Yan-Ling Yang; Yan-Qin Shen (Journal of Molecular Neuroscience, 2021)

Molecular mechanism underlying Pyropia haitanensis PhHsp22-mediated increase in the high-temperature tolerance of Chlamydomonas reinhardtii - Jing Chang; Jianzhi Shi; Jianzhang Lin; Dehua Ji; Yan Xu; Changsheng Chen; Wenlei Wang; Chaotian Xie (Journal of Applied Phycology, 2021)
Global warming is one of the key limiting factors affecting the cultivation of Pyropia haitanensis which is an economically important macroalgae species grown in southern China. However, the mechanism underlying the high-temperature tolerance of P. haitanensis remains largely unknown. In a previous study, we showed that the expression of the small heat shock protein 22 gene ( Hsp22 ) is upregulated in P. haitanensis in response to high-temperature stress, but the associated regulatory mechanism was not fully elucidated. In this study, a transgenic Chlamydomonas reinhardtii expression system was used to functionally characterize P. haitanensis Hsp22 . Our analyses indicated that the C-terminal of PhHsp22 is highly conserved and contains an A-crystal structure domain. A phylogenetic analysis revealed PhHsp22 is not closely related to small heat shock protein genes in other species. Additionally, PhHsp22 expression significantly increased at 3 and 6 h after initiating 33 °C treatment, which improved the survival rate of transgenic C. reinhardtii during the early stage of high-temperature treatment. The further transcriptome analysis revealed that PhHsp22 expression can promote pathways related to energy metabolism, metabolites metabolism, and protein homeostasis in transgenic C. reinhardtii cells exposed to high temperatures. Therefore, PhHsp22 may be crucial for the response of Pyropia species to high-temperature stress. Furthermore, this gene may be useful for breeding new high-temperature algal strains.

Molecular cloning and functional characterization of the hypoxia-inducible factor-1α in bighead carp (Aristichthys nobilis) - Yan Lin; Ling-Hong Miao; Bo Liu; Bing-Wen Xi; Liang-Kun Pan; Xian-Ping Ge (Fish Physiology and Biochemistry, 2021)

Population-based meta-analysis of chloroquine: informing chloroquine pharmacokinetics in COVID-19 patients - Xueting Yao; Xiaoyu Yan; Xiaohan Wang; Ting Cai; Shun Zhang; Cheng Cui; Xiaoxu Wang; Zhe Hou; Qi Liu; Haiyan Li; Jing Lin; Zi Xiong; et al. (European Journal of Clinical Pharmacology, 2021)
Aims Chloroquine (CQ) has been repurposed to treat coronavirus disease 2019 (COVID-19). Understanding the pharmacokinetics (PK) in COVID-19 patients is essential to study its exposure–efficacy/safety relationship and provide a basis for a possible dosing regimen optimization. Subject and methods In this study, we used a population-based meta-analysis approach to develop a population PK model to characterize the CQ PK in COVID-19 patients. An open-label, single-center study (ethical review approval number: PJ-NBEY-KY-2020-063-01) was conducted to assess the safety, efficacy, and pharmacokinetics of CQ in patients with COVID-19. The sparse PK data from 50 COVID-19 patients, receiving 500 mg CQ phosphate twice daily for 7 days, were combined with additional CQ PK data from 18 publications. Results A two-compartment model with first-order oral absorption and first-order elimination and an absorption lag best described the data. Absorption rate (ka) was estimated to be 0.559 h −1 , and a lag time of absorption (ALAG) was estimated to be 0.149 h. Apparent clearance (CL/F) and apparent central volume of distribution (V2/F) was 33.3 l/h and 3630 l. Apparent distribution clearance (Q/F) and volume of distribution of peripheral compartment (Q3/F) were 58.7 l/h and 5120 l. The simulated CQ concentration under five dosing regimens of CQ phosphate were within the safety margin (400 ng/ml). Conclusion Model-based simulation using PK parameters from the COVID-19 patients shows that the concentrations under the currently recommended dosing regimen are below the safety margin for side-effects, which suggests that these dosing regimens are generally safe. The derived population PK model should allow for the assessment of pharmacokinetics–pharmacodynamics (PK-PD) relationships for CQ when given alone or in combination with other agents to treat COVID-19.

The role of lime in dredged mud dewatered by a plate and frame filter press and potential substitutes - Yan Cui; Wei Zhu; Silin Wu; Jiming Liu; Hao Hou; Naixi Lin (Environmental Science and Pollution Research, 2021)

Increased depression risk for elderly women with high blood levels of strontium and barium - Jia Lv; Yan-ling Li; Wen-qiang Ren; Rong Li; Jian-rong Chen; Chao Bao; Zhi-ping Du; Shun Feng; Ling Gu; Hui Gao; Kai-yong Liu; Lin-sheng Yang; et al. (Environmental Chemistry Letters, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

Carbon isotope variations of modern soils in the eastern margin of the Tibetan Plateau and their controlling factors - Lin Qi; Yan-song Qiao; Zong-xiu Liu; Sha-sha Peng; Yu Cheng; Yan Wang; Xu-jiao Zhang; Ming-zhong Tian; Shuai-bin Yang; Wen-bin Bai (Journal of Mountain Science, 2021)

Improving long-baseline rapid GPS time transfers by a modified common-view method - Wen-Hung Tseng; Shinn-Yan Lin (GPS Solutions, 2021)

Formation and driving factors of sulfate in PM2.5 at a high-level atmospheric SO2 city of Yangquan in China - Cheng Wang; Yulong Yan; Yueyuan Niu; Rumei Li; Yang Xu; Dongmei Hu; Jing Wu; Lin Peng (Air Quality, Atmosphere & Health, 2021)

Fertilization alters protistan consumers and parasites in crop‐associated microbiomes - Anqi Sun; Xiao‐Yan Jiao; Qinglin Chen; Pankaj Trivedi; Zixin Li; Fangfang Li; Yong Zheng; Yongxin Lin; Hang‐Wei Hu; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Crop plants carry an enormous diversity of microbiota that provide massive benefits to hosts. Protists, as the main microbial consumers and a pivotal driver of biogeochemical cycling processes, remain largely understudied in the plant microbiome. Here, we characterized the diversity and composition of protists in sorghum leaf phyllosphere, and rhizosphere and bulk soils, collected from an 8‐year field experiment with multiple fertilization regimes. Phyllosphere was an important habitat for protists, dominated by Rhizaria, Alveolata and Amoebozoa. Rhizosphere and bulk soils had a significantly higher diversity of protists than the phyllosphere, and the protistan community structure significantly differed among the three plant–soil compartments. Fertilization significantly altered specific functional groups of protistan consumers and parasites. Variation partitioning models revealed that soil properties, bacteria and fungi predicted a significant proportion of the variation in the protistan communities. Changes in protists may in turn significantly alter the compositions of bacterial and fungal communities from the top‐down control in food webs. Altogether, we provide novel evidence that fertilization significantly affects the functional groups of protistan consumers and parasites in crop‐associated microbiomes, which have implications for the potential changes in their ecological functions under intensive agricultural managements.

CXCL10/CXCR3 Signaling in the DRG Exacerbates Neuropathic Pain in Mice - Yan-Fang Kong; Wei-Lin Sha; Xiao-Bo Wu; Lin-Xia Zhao; Ling-Jie Ma; Yong-Jing Gao (Neuroscience Bulletin, 2021)

PCDD/Fs characteristics in flue gas and surrounding environment of iron and steel smelting industry - Mingxiu Zhan; Yufeng Ma; Tong Chen; Xiaoqing Lin; Shiying Zhang; Shuaixi Xu; Xiaodong Li; Jianhua Yan (Environmental Science and Pollution Research, 2021)

Fluorine enrichment of vegetables and soil around an abandoned aluminium plant and its risk to human health - Lingling He; Chenglong Tu; Shouyang He; Jiulai Long; Ya Sun; Yan Sun; Changhu Lin (Environmental Geochemistry and Health, 2021)

The regional difference in engineering-control and tillage factors of Chinese Soil Loss Equation - Rui-yin Chen; Dong-chun Yan; An-bang Wen; Zhong-lin Shi; Jia-cun Chen; Yuan Liu; Tai-li Chen (Journal of Mountain Science, 2021)

Complete genome sequence of a novel foveavirus isolated from Allium sativum L. in China - Qi Luo; Shuzhen Hu; Qi Lin; Fei Xu; Jiejun Peng; Hongying Zheng; Guanwei Wu; Shaofei Rao; Jianping Chen; Yuwen Lu; Fengling Guo; Fei Yan (Archives of Virology, 2021)

Lentibacillus saliphilus. sp. nov., a moderately halophilic bacterium isolated from a saltern in Korea - Yun Wang; Gang-Qiang Jiang; Hong-Ping Lin; Peng Sun; Hong-Yan Zhang; Dong-Mei Lu; Li-Yun Wang; Chang-Jin Kim; Shu-Kun Tang (Archives of Microbiology, 2021)

Ecological Conservation Redline will promote harmony between humans and nature in the future - Yan Wang; Jixi Gao; Changxin Zou; Delin Xu; Naifeng Lin; Kun Zhang; Lixia Wang (Ambio, 2021)

Small RNA Sequencing Analysis of Germinating Single-bud Seedcane Sett in Sugarcane - Kai-Chao Wu; Lin Xu; Zhi-Nian Deng; Tian Pang; Rong-Hua Zhang; Yi-Jie Li; Xiao-Yan Liu; Cheng-Feng Huang; Wen-Xian Qin; Jian-Feng Wei; Li-Ping Wei; Yang-Rui Li; et al. (Sugar Tech, 2021)

Molecular characterization of miRNA genes and their expression in Dimocarpus longan Lour - Yuling Lin; Yan Chen; Youjing Zeng; Shuting Zhang; Zihao Zhang; YuKun Chen; Jiawei Gong; Zhongxiong Lai (Planta, 2021)

Projections from Infralimbic Cortex to Paraventricular Thalamus Mediate Fear Extinction Retrieval - Yan Tao; Cheng-Yun Cai; Jia-Yun Xian; Xiao-Lin Kou; Yu-Hui Lin; Cheng Qin; Hai-Yin Wu; Lei Chang; Chun-Xia Luo; Dong-Ya Zhu (Neuroscience Bulletin, 2021)

Engrafted primary type-2 astrocytes improve the recovery of the nigrostriatal pathway in a rat model of Parkinson's disease - Yanyun Sun; Xiao-jun Lu; Xinghui Fu; Ye Zhang; Yan Zhan; Jiabing Liu; Lingxia Zhao; Chun-lin Xia (Molecular and Cellular Biochemistry, 2021)

Identification of contaminants as members of the Bacillus pumilus group and analysis of contamination sources in the cultivation of Pleurotus geesteranus mushrooms - Na Lu; Wei-Dong Yuan; You-Liang Wu; Ji-Ling Song; Lin Ma; Wei-Ke Wang; Jing Yan; Zai-Ming Chen; Qing Chen (Journal of Plant Pathology, 2021)

Assisted selection of eating quality progeny of indica (O. sativa L. ssp. indica) and japonica (O. sativa L. ssp. japonica) hybrids using rice starch properties - Ting Mao; Zhan Zhang; Shan Jun Ni; Yi Zhou Zhao; Xin Li; Li Li Zhang; Yan Liu; Cheng Shun Zhong; He Huang; Shao Lin Wang; Xu Li (Genetic Resources and Crop Evolution, 2021)

Genotyping-by-sequencing to determine the genetic structure of a Tibetan medicinal plant Swertia mussotii Franch. - Yan Qiao; Fengxian Guo; Naxin Huo; Lin Zhan; Jiaqing Sun; Xixi Zuo; Zeguang Guo; Yong Q. Gu; Yi Wang; Yue Liu (Genetic Resources and Crop Evolution, 2021)

Injection route affects intra-articular hyaluronic acid distribution and clinical outcome in viscosupplementation treatment for knee osteoarthritis: a combined cadaver study and randomized clinical trial - Jun Xiao; Yong Hu; Lin Huang; Zhi-Fa Huang; Wei-Zhou Jiang; Yu-Qiang Luo; Meng-Yan Jia; Di Chen; Zhan-Jun Shi (Drug Delivery and Translational Research, 2021)

Differences in Soil Microbial Community Composition Between Suppressive and Root Rot-Conducive in Tobacco Fields - Yaru Ding; Yulan Chen; Zhengquan Lin; Yangyang Tuo; Hongli Li; Yan Wang (Current Microbiology, 2021)

Sex-specific effects of cigarette smoking on caudate and amygdala volume and resting-state functional connectivity - Fuchun Lin; Xu Han; Yao Wang; Weina Ding; Yawen Sun; Yan Zhou; Hao Lei (Brain Imaging and Behavior, 2021)

Associations of Serum Selenium Levels in the First Trimester of Pregnancy with the Risk of Gestational Diabetes Mellitus and Preterm Birth: a Preliminary Cohort Study - Peng Ju Liu; Aimin Yao; Liangkun Ma; Xiao Yan Chen; Song Lin Yu; Yanping Liu; Yi Xuan Hou (Biological Trace Element Research, 2021)

Effect of soil moisture on pupation behavior and inhabitation of Spodoptera frugiperda (Lepidoptera: Noctuidae) - Yan Shi; Lin-Yu Li; Sohaib Shahid; Guy Smagghe; Tong-Xian Liu (Applied Entomology and Zoology, 2021)

The substrate‐dependent regulatory effects of the AfeI /R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles - Xue‐Yan Gao; Chang‐Ai Fu; Likai Hao; Xiu‐Feng Gu; Rui Wang; Jian‐Qiang Lin; Xiang‐Mei Liu; Xin Pang; Cheng‐Jia Zhang; Jian‐Qun Lin; Lin‐Xu Chen (Environmental Microbiology, 2021)
Summary A LuxI/R‐like quorum sensing (QS) system (AfeI/R) has been reported in the acidophilic and chemoautotrophic Acidithiobacillus spp. However, the function of AfeI/R remains unclear because of the difficulties in the genetic manipulation of these bacteria. Here, we constructed different afeI mutants of the sulfur‐ and iron‐oxidizer A . ferrooxidans , identified the N‐acyl homoserine lactones (acyl‐HSLs) synthesized by AfeI, and determined the regulatory effects of AfeI/R on genes expression, extracellular polymeric substance synthesis, energy metabolism, cell growth and population density of A . ferrooxidans in different energy substrates. Acyl‐HSLs‐mediated distinct regulation strategies were employed to influence bacterial metabolism and cell growth of A . ferrooxidans cultivated in either sulfur or ferrous iron. Based on these findings, an energy‐substrate‐dependent regulation mode of AfeI/R in A . ferrooxidans was illuminated that AfeI/R could produce different types of acyl‐HSLs and employ specific acyl‐HSLs to regulate specific genes in response to different energy substrates. The discovery of the AfeI/R‐mediated substrate‐dependent regulatory mode expands our knowledge on the function of QS system in the chemoautotrophic sulfur‐ and ferrous iron‐oxidizing bacteria, and provides new insights in understanding energy metabolism modulation, population control, bacteria‐driven bioleaching process, and the coevolution between the acidophiles and their acidic habitats.

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Mechanisms of high-frequency dinoflagellate blooms of Scrippsiella trochoidea in Daya Bay, South China Sea - Yuan Tian; Simin Hu; Xianzhi Lin; Hui Huang; Xingyu Song; Yan Yan; Xuedong Xie; Tao Li; Sheng Liu (Journal of Oceanology and Limnology, 2021)

Understanding the dynamical-microphysical-electrical processes associated with severe thunderstorms over the Beijing metropolitan region - Xiushu Qie; Shanfeng Yuan; Zhixiong Chen; Dongfang Wang; Dongxia Liu; Mengyu Sun; Zhuling Sun; Abhay Srivastava; Hongbo Zhang; Jingyu Lu; Hui Xiao; Yongheng Bi; et al. (Science China Earth Sciences, 2021)

Improved control of Frankliniella occidentalis on greenhouse pepper through the integration of Orius sauteri and neonicotinoid insecticides - Qing-cai Lin; Hao Chen; Dirk Babendreier; Jin-ping Zhang; Feng Zhang; Xiao-yan Dai; Zuo-wen Sun; Zhao-peng Shi; Xiao-lin Dong; Guang-an Wu; Yi Yu; Li Zheng; et al. (Journal of Pest Science, 2021)

Amniotic fluid mesenchymal stem cells repair mouse corneal cold injury by promoting mRNA N4-acetylcytidine modification and ETV4/JUN/CCND2 signal axis activation - Xinfeng Fei; Yuying Cai; Feng Lin; Yongyi Huang; Te Liu; Yan Liu (Human Cell, 2021)
Severe corneal injury is one of the main causes of loss of visual function. Mesenchymal stem cells (MSCs) have the ability to repair damaged cells in vivo. The present study aimed to explore whether MSCs could function as a cell therapy tool to replace traditional methods to treat corneal injury. CD44 + /CD105 + mesenchymal stem cells isolated from mouse amniotic fluid (mAF-MSCs) were injected into mice after cryoinjury to induce corneal endothelial cell injury. Histopathological assays indicated that mAF-MSCs could promote the growth of corneal epithelial cells, reduce keratitis, and repair the corneal damage caused by low temperature. cDNA microarray analysis revealed that the mAF-MSCs affected the expression patterns of mRNAs related to cell proliferation and differentiation pathways in the mice after transplantation. The results of quantitative real-time PCR and western blotting revealed that NAT12, NAT10, and the ETV4/JUN/CCND2 signaling axis were elevated significantly in the mAF-MSC-transplantation group, compared with those in the phosphate-buffered saline-treated groups. High performance liquid chromatography–mass spectroscopy results revealed that mAF-MSCs could promote mRNA N4-acetylcytidine (ac4C) modification and high expression of N -acetyltransferase in the eyeballs. RNA immunoprecipitation-PCR results showed that a specific product comprising Vegfa , Klf4 , Ccnd2 , Jun , and Etv4 mRNA specific coding region sites could be amplified using PCR from complexes formed in mAF-MSC-transplanted samples cross-linked with anti-ac4C antibodies. Thus, mouse amniotic fluid MSCs could repair the mouse corneal cold injury by promoting the ETV4/JUN/CCND2 signal axis activation and improving its stability by stimulating N4-acetylcytidine modification of their mRNAs.

New application of lanthanum-modified bentonite (Phoslock®) for immobilization of arsenic in sediments - Jingzhen Cui; Dan Wang; Juan Lin; Yan Wang; Mingyi Ren; Youwei Yang; Pengling Shi (Environmental Science and Pollution Research, 2021)

Low ambient temperature increases hospital re-admissions for systemic lupus erythematosus in humid subtropical region: a time series study - Qian Wu; Zhiwei Xu; Yi-Lin Dan; Peng Wang; Yan-Mei Mao; Chan-Na Zhao; Yan-Feng Zou; Dong-Qing Ye; Wenbiao Hu; Hai-Feng Pan (Environmental Science and Pollution Research, 2021)

Multifractal characteristics and spatial variability of soil particle-size distribution in different land use patterns in a small catchment of the Three Gorges Reservoir Region, China - Tai-li Chen; Zhong-lin Shi; An-bang Wen; Dong-chun Yan; Jin Guo; Jia-cun Chen; Yuan Liu; Rui-yin Chen (Journal of Mountain Science, 2021)

Inversion analysis of the shear strength parameters for a high loess slope in the limit state - Xiao-yan Lin; Lin-fan Zhang; Ze Yang; Ping Li; Tong-lu Li (Journal of Mountain Science, 2021)

Complete genome sequence of a new achyranthes virus A isolate from Achyranthes bidentata in China - Xinyang Wu; Yuchao Lai; Lanqing Lv; Kelei Han; Ziqiang Chen; Yuwen Lu; Jiejun Peng; Lin Lin; Jianping Chen; Hongying Zheng; Fei Yan (Archives of Virology, 2021)

Analysis of fracturing characteristics of unconfined rock plate under edge-on impact loading - Yixian Wang; Hang Lin; Yanlin Zhao; Xian Li; Panpan Guo; Yan Liu (European Journal of Environmental and Civil Engineering, 2020)

Nitrogen Regulates the Grain Yield, Antioxidant Attributes, and Nitrogen Metabolism in Fragrant Rice Grown Under Lead-Contaminated Soil - Huoyi Feng; Yuzhan Li; Yangfan Yan; Xinhang Wei; Yihan Yang; Long Zhang; Lin Ma; Wu Li; Xiangru Tang; Zhaowen Mo (Journal of Soil Science and Plant Nutrition, 2020)

Effects of Single-Dose and Long-Term Ketamine Administration on Tau Phosphorylation–Related Enzymes GSK-3β, CDK5, PP2A, and PP2B in the Mouse Hippocampus - Yanning Li; Gehua Wen; Runtao Ding; Xinghua Ren; Chenchen Jing; Lin Liu; Jun Yao; Guohua Zhang; Yan Lu; Baoman Li; Xu Wu (Journal of Molecular Neuroscience, 2020)

Aggregation-Induced Emission Properties of Glutathione and L-Cysteine Capped CdS Quantum Dots and their Application as Zn(II) Probe - Caixia Yao; Tianyang Lin; Zongjuan Lian; Shenghua Liao; Zhengyu Yan; Shengmei Wu (Journal of Fluorescence, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Valine acts as a nutritional signal in brain to activate TORC1 and attenuate postprandial ammonia-N excretion in Chinese perch (Siniperca chuatsi) - Jie Wang; Xu-Fang Liang; Shan He; Yan-Peng Zhang; Jiao Li; Kang Huang; Lin-Jie Shi; Ping Ren (Fish Physiology and Biochemistry, 2020)

Epidemiological analysis of Group A Streptococcus infections in a hospital in Beijing, China - Hongxin Li; Lin Zhou; Yong Zhao; Lijuan Ma; Jing Xu; Yan Liu; Qin Qin; Jin Hu; Xiaoyan Liu (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Relationship Between Plasma Copper Concentration and Body Fat Distribution in Children in China: a Cross-Sectional Study - Jingjing Liang; Fengyan Chen; Guoqing Fang; Xin Zhang; Yan Li; Bingjie Ma; Suifang Lin; Jialiang Pan; Zheqing Zhang (Biological Trace Element Research, 2020)

Nuclear Factor-κB Pathway Mediates the Molecular Pathogenesis of LMNA-Related Muscular Dystrophies - Yanbin Fan; Dandan Tan; Xu Zhang; Danyu Song; Xingzhi Chang; Shuang Wang; Hui Yan; Lin Ge; Haipo Yang; Carsten Bönnemann; Jingying Liu; Suxia Wang; et al. (Biochemical Genetics, 2020)

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

Ferrous iron-induced increases in capitate glandular trichome density and upregulation of CbHO-1 contributes to increases in blinin content in Conyza blinii - Tianrun Zheng; Maojia Wang; Junyi Zhan; Wenjun Sun; Qin Yang; Zhiyi Lin; Tongliang Bu; Zizhong Tang; Chenglei Li; Jun Yan; Zhi Shan; Hui Chen (Planta, 2020)

Illumina sequencing revealed roles of microRNAs in different aluminum tolerance of two citrus species - Yang-Fei Zhou; Yan-Yu Wang; Wei-Wei Chen; Li-Song Chen; Lin-Tong Yang (Physiology and Molecular Biology of Plants, 2020)

Mechanism of contractile dysfunction induced by serotonin in coronary artery in spontaneously hypertensive rats - Hao Wang; Xiao-Yan Gao; Fang Rao; Hui Yang; Zhao-Yu Wang; Lin Liu; Su-Juan Kuang; Qi Wu; Chun-Yu Deng; Jing-Song Xu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

MicroRNA-761 modulates foam cell formation and inflammation through autophagy in the progression of atherosclerosis - Chao Wang; Wei Yang; Xiaofei Liang; Wei Song; Jing Lin; Yan Sun; Xiuru Guan (Molecular and Cellular Biochemistry, 2020)

A Comparative Study of Associated Microbiota Between Pig Farm and Pig Slaughterhouse in Guangdong, China - Jian-Yong Wu; Yan-Shan Zhu; Cheng Guo; Yao Xia; Zhong-Min Guo; Qian-Lin Li; Jia-Hai Lu (Current Microbiology, 2020)

Characterization of a Protease Hyper-Productive Mutant of Bacillus pumilus by Comparative Genomic and Transcriptomic Analysis - Yong-Cheng Liu; Lin-Li Han; Tian-Yu Chen; Yan-Bing Lu; Hong Feng (Current Microbiology, 2020)

A calculation model to assess the crack propagation length of rock block in clastic flow - Yang Liu; Yong You; Jin-feng Liu; Shu-xi Zhao; Dong-xu Yang; Dao-chuan Liu; Lin Liu; Yan-fang Xie; Kai-cheng Yang (Journal of Mountain Science, 2020)

Arthrobacter sedimenti sp. nov., isolated from river sediment in Yuantouzhu park, China - Pei Lin; Zheng-Fei Yan; Chang-Tian Li (Archives of Microbiology, 2020)

Intrusion of Kuroshio Helps to Diminish Coastal Hypoxia in the Coast of Northern South China Sea - Hon-Kit Lui; Chen-Tung Arthur Chen; Wei-Ping Hou; Jian-Ming Liau; Wen-Chen Chou; You-Lin Wang; Chau-Ron Wu; Jay Lee; Yi-Chia Hsin; Yan-Yu Choi (Frontiers in Marine Science, 2020)

One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko - Wan-Rong Niu; Cong-Liang Guo; Deng-Ji Lou; Rui-Ting Li; Qiao Xiang; Yu-Lin Zou; Xiu-Ming Cui; Xiao-Yan Yang (Natural Product Research, 2020)

Characterization of transcription activation domain of EcaICE1 and its interaction with EcaSIZ1 in Eucalyptus camaldulensis - Ziyang Zhang; Ling Cheng; Weihua Zhang; Jianlin Hu; Yan Liu; Yuanzhen Lin (Trees, 2020)

Impact of prophylactic/preemptive donor lymphocyte infusion and intensified conditioning for relapsed/refractory leukemia: a real-world study - Yu Wang; Qi-Fa Liu; De-Pei Wu; Jing-Bo Wang; Xi Zhang; Heng-Xiang Wang; Feng Gao; Shun-Qing Wang; Zi-Min Sun; Jian Ouyang; Kai-Lin Xu; Su-Jun Gao; et al. (Science China Life Sciences, 2020)

Mu-Opioid Receptors Expressed in Glutamatergic Neurons are Essential for Morphine Withdrawal - Xin-Yan Zhang; Qing Li; Ye Dong; Wei Yan; Kun Song; Yong-Qin Lin; Yan-Gang Sun (Neuroscience Bulletin, 2020)

A novel freshwater cyanophage vB_MelS-Me-ZS1 infecting bloom-forming cyanobacterium Microcystis elabens - Wei Lin; Dengfeng Li; Zhitong Sun; Yigang Tong; Xiaojun Yan; Chunlin Wang; Xianglilan Zhang; Guangqian Pei (Molecular Biology Reports, 2020)

Emerging relationship between RNA helicases and autophagy - Miao-miao Zhao; Ru-sha Wang; Yan-lin Zhou; Zheng-gang Yang (Journal of Zhejiang University-SCIENCE B, 2020)

Verticillin A inhibits colon cancer cell migration and invasion by targeting c-Met - Qian-qian Liu; Xue-li Zeng; Yue-lin Guan; Jing-xin Lu; Kai Tu; Fei-yan Liu (Journal of Zhejiang University-SCIENCE B, 2020)

Grape seed proanthocyanidin extract ameliorates hepatic lipid accumulation and inflammation in grass carp (Ctenopharyngodon idella) - Rong-Hua Lu; Chao-Bin Qin; Feng Yang; Wen-Ya Zhang; Yu-Ru Zhang; Guo-Kun Yang; Li-Ping Yang; Xiao-Lin Meng; Xiao Yan; Guo-Xing Nie (Fish Physiology and Biochemistry, 2020)

Modification-bioremediation of copper, lead, and cadmium-contaminated soil by combined ryegrass (Lolium multiflorum Lam.) and Pseudomonas aeruginosa treatment - Guang-yu Shi; Ying-jia Yan; Zhi-qiang Yu; Lu Zhang; Yuan-yuan Cheng; Wei-lin Shi (Environmental Science and Pollution Research, 2020)

Sodium Para-aminosalicylic Acid Reverses Changes of Glutamate Turnover in Manganese-Exposed Rats - Zhao-Cong Li; Fang Wang; Shao-Jun Li; Lin Zhao; Jun-Yan Li; Yue Deng; Xiao-Juan Zhu; Yu-Wen Zhang; Dong-Jie Peng; Yue-Ming Jiang (Biological Trace Element Research, 2020)

Psychroflexus maritimus sp. nov., isolated from coastal sediment - Yan-Lin Zhong; Rui Zhang; Xiao-Yu Zhang; Li-Xue Yu; Meng-Fan Zhao; Zong-Jun Du (Archives of Microbiology, 2020)

Underway Measurement of Dissolved Inorganic Carbon (DIC) in Estuarine Waters - Jinpei Yan; Qi Lin; Seng Chee Poh; Yuhong Li; Liyang Zhan (Journal of Marine Science and Engineering, 2020)
Dissolved inorganic carbon (DIC) is an important parameter of the marine carbonate system. Underway analyses of DIC are required to describe spatial and temporal changes of DIC in marine systems. In this study, we developed a microvolume flow detection method for the underway determination of DIC in marine waters, using gas-diffusion flow analysis in conjunction with electrical conductivity (EC) measurement. Only an acid carrier reagent (0.2 mol.L−1) and an ultrapure water acceptor are required for the DIC monitoring system. In this system, a sampling loop (100 µL) is used to quantify the injection sample volume, allowing micro-sample volume detection. The water sample reacts with the acid reagent to convert carbonate and bicarbonate species into CO2. The water sample is then carried into a gas-diffusion assembly, where the CO2 diffuses from the sampling stream into the acceptor stream. CO2 in the acceptor is detected subsequently by an electrical conductivity. The limit of DIC detection using ultrapure water is 0.16 mM. A good repeatability is obtained, with a relative standard deviation (RSD) of 0.56% (1 mM, n = 21). The time interval for detecting one sample is 5 min. During the observation period, measurements can be switched between standard solutions and water samples automatically. Accuracy and precision of the instrument is sufficient for the underway observation of marine DIC in estuarine waters.

Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells - Y. Y. Yan; Q. Zhang; B. Zhang; B. Yang; N. M. Lin (Natural Product Research, 2020)

Chemical constituents from the bark of bauhinia purpurea and their NO inhibitory activities - Lin Ni; Wei Huang; Yan Shi; Heshan Wang; Yatie Qiu; Huiyou Xu (Natural Product Research, 2020)

Tyrosine Hydroxylase Gene Polymorphisms Contribute to Opioid Dependence and Addiction by Affecting Promoter Region Function - Jun-lin Liu; Shao-qing Li; Feng Zhu; Yu-xiang Zhang; Ya-nan Wu; Jing-si Yang; Bao Zhang; Chun-xia Yan (NeuroMolecular Medicine, 2020)

Genome-wide identification of the Sec-dependent secretory protease genes in Erwinia amylovora and analysis of their expression during infection of immature pear fruit - Wang-bin Zhang; Hai-lin Yan; Zong-cai Zhu; Chao Zhang; Pei-xiu Du; Wen-jun Zhao; Wei-min Li (Journal of Zhejiang University-SCIENCE B, 2020)

Cerebral Ischemia-Reperfusion Injury: Lysophosphatidic Acid Mediates Inflammation by Decreasing the Expression of Liver X Receptor - Xiaoyun Zeng; Zhixiu Luo; Junyi Wu; Jie Zhou; Yandong Shan; Yang Zhu; Guilin Yan; Yahang Lin; Chao Wang (Journal of Molecular Neuroscience, 2020)

RETRACTED ARTICLE: A New Luminescent Zn(II) Complex: Selective Sensing of Cr2O72− and Prevention Activity Against Orthodontic Root Absorption by Suppressing Inflammatory Response - Yan-Feng Zhu; Wei-Qun Guan; Fei Lin; Wei-Hui Chen (Journal of Fluorescence, 2020)

Gene UCHL1 expresses specifically in mouse uterine decidual cells in response to estrogen - Lishuang Hao; Di Song; Mengfei Zhuang; Yan Shi; Lin Yu; Yaping He; Jian Wang; Tingting Zhang; Zhaogui Sun (Histochemistry and Cell Biology, 2020)

Estimating purple-soil moisture content using Vis-NIR spectroscopy - Yu Gou; Jie Wei; Jin-lin Li; Chen Han; Qing-yan Tu; Chun-hong Liu (Journal of Mountain Science, 2020)

Atmospheric Volatile Organic Compounds (VOCs) in China: a Review - Ahsan Mozaffar; Yan-Lin Zhang (Current Pollution Reports, 2020)

China’s ecological conservation redline: A solution for future nature conservation - Jixi Gao; Yan Wang; Changxin Zou; Delin Xu; Naifeng Lin; Lixia Wang; Kun Zhang (Ambio, 2020)

Prenylated isoflavones with potential antiproliferative activities from Mappianthus iodoides - Yan-Ping Liu; Li-Li Sun; Xiang-Lin Zhang; Hai-Yuan Niu; Zheng-Hong Pan; Yan-Hui Fu (Natural Product Research, 2020)

Dietary risk assessment of pesticide residues on Tremella fuciformis Berk (snow fungus) from Fujian Province of China - Qinghua Yao; Sun-an Yan; Hanzhen Chen; Jie Li; Qiu Lin (Food Additives & Contaminants: Part A, 2020)

The crucial role of bacterial laccases in the bioremediation of petroleum hydrocarbons - Yan Zhang; Dong-Fa Lin; Jun Hao; Zhi-Hao Zhao; Ying-Jiu Zhang (World Journal of Microbiology and Biotechnology, 2020)

Multiplex RT–PCR Assay for the Simultaneous Detection and Identification of Five Sugarcane Viruses - Xiao-Yan Feng; Wen-Zhi Wang; Lin-Bo Shen; Jun-Gang Wang; Guo-Ru Xiong; Cui-Lian Feng; Ting-Ting Zhao; Shu-Zhen Zhang (Sugar Tech, 2020)

Observations and modeling of flat subduction and its geological effects - Zhiyong Yan; Lin Chen; Xiong Xiong; Kai Wang; Renxian Xie; Hou Tze Hsu (Science China Earth Sciences, 2020)

Comparative analysis and natural evolution of squalene epoxidase in three Fritillaria species - Xu Lu; Lin-Ning Zhang; Jin-Fa Du; Xiao-Yan Zheng; Hui-Jun Li; Ping Li; Gui-Zhong Xin; Yan Jiang (Plant Molecular Biology, 2020)

RETRACTED ARTICLE: Paeoniflorin attenuates early brain injury through reducing oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats - Tao Wang; Ling Xu; Lei Gao; Lin Zhao; Xin-hong Liu; Yan-yan Chang; Yun-lin Liu (Metabolic Brain Disease, 2020)

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study - Shao-rui Hao; Ren Yan; Shan-yan Zhang; Jiang-shan Lian; Huan Cai; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Comparison of the effects of deep and moderate neuromuscular block on respiratory system compliance and surgical space conditions during robot-assisted laparoscopic radical prostatectomy: a randomized clinical study - Shao-jun Zhu; Xiao-lin Zhang; Qing Xie; Yan-feng Zhou; Kui-rong Wang (Journal of Zhejiang University-SCIENCE B, 2020)

Negative effects of rare earth oxide nanoparticles of La2O3, Nd2O3, and Gd2O3 on the ammonia-oxidizing microorganisms - Yan Yue; Lin Qi; Yan Li; Jichen Wang; Congcong Shen; Yuan Ge (Journal of Soils and Sediments, 2020)

Synergistic effects of pazopanib and hyperthermia against uterine leiomyosarcoma growth mediated by downregulation of histone acetyltransferase 1 - Chiao-Yun Lin; Angel Chao; Ren-Chin Wu; Li-Yu Lee; Shir-Hwa Ueng; Chia-Lung Tsai; Yun-Shien Lee; Meng-Ting Peng; Lan-Yan Yang; Huei-Jean Huang; Hsin-Shih Wang; Chyong-Huey Lai (Journal of Molecular Medicine, 2020)

Cinnamaldehyde improves the growth performance and digestion and absorption capacity in grass carp (Ctenopharyngodon idella) - Yang Zhou; Wei-Dan Jiang; Jin-Xiu Zhang; Lin Feng; Pei Wu; Yang Liu; Jun Jiang; Sheng-Yao Kuang; Ling Tang; Yan Peng; Xiao-Qiu Zhou (Fish Physiology and Biochemistry, 2020)

Environmental risk mapping of potential abandoned uranium mine contamination on the Navajo Nation, USA, using a GIS-based multi-criteria decision analysis approach - Yan Lin; Joseph Hoover; Daniel Beene; Esther Erdei; Zhuoming Liu (Environmental Science and Pollution Research, 2020)

Agronomic and environmental benefits of nutrient expert on maize and rice in Northeast China - Yin Wang; Chunlin Li; Yuxi Li; Lin Zhu; Shuoran Liu; Li Yan; Guozhong Feng; Qiang Gao (Environmental Science and Pollution Research, 2020)

Enhancement of the activity of Cu/TiO2 catalyst by Eu modification for selective catalytic reduction of NOx with NH3 - Yuan-zhen Liu; Qi-yan Xu; Rui-tang Guo; Chao-peng Duan; Gui-lin Wu; Yu-fang Miao; Jing-wen Gu (Environmental Science and Pollution Research, 2020)

Effect of Dietary Zinc Level on Egg Production Performance and Eggshell Quality Characteristics in Laying Duck Breeders in Furnished Cage System - Liang Huang; Jiajia Shen; Yan Feng; Daquan Li; Wence Wang; Lin Yang; Yongwen Zhu (Biological Trace Element Research, 2020)

Gastric smooth muscle cells manifest an abnormal phenotype in Parkinson’s disease rats with gastric dysmotility - Xiao-Lin Xiu; Li-Fei Zheng; Xiao-Yu Liu; Yan-Yan Fan; Jin-Xia Zhu (Cell and Tissue Research, 2020)

Seonamhaeicola sediminis sp. nov., isolated from marine sediment - Xiao-Yu Zhang; Rui Zhang; Yan-Lin Zhong; Dai-Wei Xianyu; Zong-Jun Du (Archives of Microbiology, 2020)

Zooplankton community size-structure change and mesh size selection under the thermal stress caused by a power plant in a semi-enclosed bay - Qianwen Shao; Yifeng Zhu; Meixia Dai; Xia Lin; Chengxu Zhou; Xiaojun Yan (Acta Oceanologica Sinica, 2020)

Three new pterocarpans from the aerial parts of Abrus Precatorius - Yan Li; Jie-Wei Wu; Hai-Bo Tan; Bai-Lin Li; Sheng-Xiang Qiu (Natural Product Research, 2020)

Three new phenylacetamide glycosides from Dracocephalum tanguticum Maxim and their anti-hyperglycemic activity - En-Guang Ma; Hai-Yan Wu; Li-Jiao Hu; Min Wei; Lin-Yun Mou; Gan-Peng Li (Natural Product Research, 2020)

General review of optical polarization remote sensing - Lei Yan; Yanfei Li; V. Chandrasekar; Hugh Mortimer; Jouni Peltoniemi; Yi Lin (International Journal of Remote Sensing, 2020)

Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in Aβ oligomer-treated mice - Liping Chen; Hanbo Pan; Yujing Bai; Huiqin Li; Wen Yang; Zhi-Xiu Lin; Wei Cui; Yan-Fang Xian (Psychopharmacology, 2020)

Beyond resource limitation: an expanded test of the niche dimension hypothesis for multiple types of niche axes - Xuebin Yan; Jeffrey Diez; Kailing Huang; Shaopeng Li; Xi Luo; Xinyu Xu; Fanglong Su; Lin Jiang; Hui Guo; Shuijin Hu (Oecologia, 2020)

Toxicity assessment of electrochemical advanced oxidation process-treated groundwater from a gas station with petrochemical contamination - How-Ran Chao; Danielle E. Que; Alisha C. Aquino; Yan-You Gou; Lemmuel L. Tayo; Yi-Hsien Lin; Ming-Hsien Tsai; Fu-Lin Hsu; I-Cheng Lu; Sheng-Lun Lin; Natwat Srikhao; Cherng-Gueih Shy; et al. (Environmental Monitoring and Assessment, 2020)

Luteimonas cellulosilyticus sp. nov., Cellulose-Degrading Bacterium Isolated from Soil in Changguangxi National Wetland Park, China - Pei Lin; Zheng-Fei Yan; Chang-Tian Li (Current Microbiology, 2020)

Miscanthus cultivation shapes rhizosphere microbial community structure and function as assessed by Illumina MiSeq sequencing combined with PICRUSt and FUNGUIld analyses - Yan Chen; Wei Tian; Yang Shao; Ying-Jun Li; Li-An Lin; Ying-Jun Zhang; Hui Han; Zhao-Jin Chen (Archives of Microbiology, 2020)

Perilipin LDP1 coordinates lipid droplets formation and utilization for appressorium‐mediated infection in Magnaporthe oryzae - Xuan Cai; Jingjing Yan; Caiyun Liu; Junjie Xing; Zhiyong Ren; Ahmed Hendy; Lu Zheng; Junbin Huang; Xiao‐Lin Chen (Environmental Microbiology, 2020)
Summary Lipid droplets (LDs) serve as one of the major reservoirs in conidia of Magnaporthe oryzae and are quickly utilized during appressorium formation. Here, we identified a gene, LDP1 , encoding a perilipin that is important for LD formation and utilization during appressorium maturation. LDP1 is highly expressed in conidium and immature appressorium. Disruption mutants of LDP1 were significantly reduced in virulence, due to appressorial turgor reduction and difficulty in penetration. LDs were significantly reduced in the Δ ldp1 mutant, indicating LDP1 was required for LDs formation. LDP1 was colocalized with the LDs in conidium and immature appressorium but was gradually separated during appressorium maturation. A typical intracellular triacylglycerol lipase, TGL1‐2, was clearly separated with LDs in conidium and immature appressorium but was well colocalized with LDs during appressorium maturation. The subcellular localization of TGL1‐2 was affected by LDP1. These data suggested that LDP1 was bound to LDs for protecting from utilization in conidia and at the early appressorium stage but was separated from LDs for lipase entering and degradation. LDP1 was phosphorylated by CPKA at Thr96, which was essential for its localization and functions. These data indicate perilipin LDP1 can coordinate LD formation and utilization for appressorium‐mediated infection of M . oryzae .

The chemical constituents from the active fractions of Eleutherine bulbosa with their antimicrobial activity - Hai Jiang; Wen-Jing Man; A-Jiao Hou; Lin Yang; Xu-Dong Xing; Mei-Ling Yan; Xin-Yue Guo; Liu Yang (Natural Product Research, 2020)

Numerical Simulation of Wave Interaction with Payloads of Different Postures Using OpenFOAM - Mingwei Yan; Xin Ma; Wei Bai; Zaibin Lin; Yibin Li (Journal of Marine Science and Engineering, 2020)
A three-dimensional numerical wave tank (NWT) is established with Open Source Field Operation and Manipulation (OpenFOAM) software and waves2foam to investigate wave interaction with payloads with different postures in the process of offshore lifting or lowering. Numerical results of regular wave interaction with a vertically suspending cylinder are presented first for validation by comparison with the published data. A series of simulation experiments are carried out, and the forces and the moments exerted by the regular waves on a fixed suspending cylinder payload and a fixed suspending cuboid payload with different postures are presented. It can be concluded from the results that the rotating rectangular payload (cuboid and cylinder) suffers a drastically changed moment when it is initially vertically placed, and the projection area of payload vertical to the force affects the corresponding force. The simulation results also show how the forces and the moments change with different posture angles. With some certain posture, the suspending payload suffers minimum forces and moments. Parametric study for the cuboid payload is done in the case of normal incidence. The influence of the payload’s size and wave parameters on forces and moments are analyzed. All of the numerical simulation results and conclusions provide the fundamentals for further research and safe control of offshore lifting or lowering.

Suggested guidelines for emergency treatment of medical waste during COVID-19: Chinese experience - Yufeng Ma; Xiaoqing Lin; Angjian Wu; Qunxing Huang; Xiaodong Li; Jianhua Yan (Waste Disposal & Sustainable Energy, 2020)

New insight into the molecular phylogeny of the genus Liparis s.l. (Orchidaceae: Malaxideae) with a new generic segregate: Blepharoglossum - Lin Li; Shih-Wen Chung; Bo Li; Song-Jun Zeng; Hai-Fei Yan; Shi-Jin Li (Plant Systematics and Evolution, 2020)
Molecular studies have shown that Liparis s.l. is polyphyletic, with the epiphytic Liparis alliance well separated from the clade representing Liparis in its restricted sense and further forming a phylogenetically heterogeneous assemblage. The generic status of Cestichis , as the key member of the epiphytic Liparis alliance, remains contentious, and the relationships between Cestichis , Stichorkis and Platystyliparis are still unclear and in need of further studies. We herein employ DNA sequence data from nuclear ITS and plastid mat K regions to clarify the generic boundaries of Cestichis and its relationship to the allied genera. Results from both Bayesian inference and maximum likelihood analysis congruently indicate that Cestichis as currently circumscribed is not monophyletic. The Blepharoglossum clade, corresponding to commonly recognized sect. Blepharoglossum , forms a monophyletic lineage closely related to the genus Oberonia instead of the core Cestichis clade. A re-evaluation of the diagnostic morphological characters reveals that this lineage represents a morphologically distinct group. Based on these results, Blepharoglossum is removed from Cestichis and elevated to generic status. Our study also sheds light on the homoplastic nature of some diagnostic morphological characters used traditionally in the taxonomy of the Malaxidinae.

Ketamine Affects the Expression of ErbB4 in the Hippocampus and Prefrontal Cortex of Rats - Runfang Xie; Shijun Hong; Yi Ye; Xueyan Wang; Fan Chen; Lin Yang; Youyi Yan; Linchuan Liao (Journal of Molecular Neuroscience, 2020)

Ultrastructural evolution, physiological traits, and carbon and nitrogen assimilation–related gene expression are compatible with the developmental transitions of parthenogenesis in Pyropia haitanensis (Bangiales, Rhodophyta) - Chenhui Zhong; Longchen Tang; Qi Lin; Xinghong Yan (Journal of Applied Phycology, 2020)

Aberrant white matter properties of the callosal tracts implicated in girls with attention-deficit/hyperactivity disorder - Qingxia Lin; Xuan Bu; Meihao Wang; Yan Liang; Hong Chen; Weiqian Wang; Yanhong Yi; Haixi Lin; Jiaxiu Zhou; Lu Lu; Xinyu Hu; Chuang Yang; et al. (Brain Imaging and Behavior, 2020)

Influence of Aphis gossypii feeding on defense strategy of native and introduced populations of Ageratina adenophora - Ying Lin; Shu-Qi He; Zhi-Hui Lu; Yu-Lin Gao; Yan-Ru Duan; Zheng-Yue Li; Bin Chen; Fu-Rong Gui (Arthropod-Plant Interactions, 2020)

Epidemiology, molecular characterization, and recombination analysis of chicken anemia virus in Guangdong province, China - Chen Tan; Zhanxin Wang; Xiaoya Lei; Junpeng Lu; Zhuanqiang Yan; Jianping Qin; Feng Chen; Qingmei Xie; Wencheng Lin (Archives of Virology, 2020)

Plastic pollution in croplands threatens long‐term food security - Dan Zhang; Ee Ling Ng; Wanli Hu; Hongyuan Wang; Pablo Galaviz; Hude Yang; Wentao Sun; Chongxiao Li; Xingwang Ma; Bin Fu; Peiyi Zhao; Fulin Zhang; et al. (Global Change Biology, 2020)
Plastic pollution is a global concern given its prevalence in aquatic and terrestrial ecosystems. Studies have been conducted on the distribution and impact of plastic pollution in marine ecosystems, but little is known on terrestrial ecosystems. Plastic mulch has been widely used to increase crop yields worldwide, yet the impact of plastic residues in cropland soils to soil health and crop production in the long term remained unclear. In this paper, using a global meta‐analysis, we found that the use of plastic mulch can indeed increase crop yields on average by 25%–42% in the immediate season due to the increase of soil temperature (+8%) and moisture (+17%). However, the unabated accumulation of film residues in the field negatively impacts its physicochemical properties linked to healthy soil and threatens food production in the long term. It has multiple negative impacts on plant growth including crop yield (at the mean rate of −3% for every additional 100 kg/ha of film residue), plant height (−2%) and root weight (−5%), and soil properties including soil water evaporation capacity (−2%), soil water infiltration rate (−8%), soil organic matter (−0.8%) and soil available phosphorus (−5%) based on meta‐regression. Using a nationwide field survey of China, the largest user of plastic mulch worldwide, we found that plastic residue accumulation in cropland soils has reached 550,800 tonnes, with an estimated 6%–10% reduction in cotton yield in some polluted sites based on current level of plastic residue content. Immediate actions should be taken to ensure the recovery of plastic film mulch and limit further increase in film residue loading to maintain the sustainability of these croplands.

Two new xanthone glycosides from Swertia punicea Hemsl. and their anti-inflammatory activity - Lin-Yun Mou; Hai-Yan Wu; En-Guang Ma; Ming-Feng Wang; Yan-Qing Duan; Sheng Lei; Gan-Peng Li (Natural Product Research, 2020)

Variation in Water Masses on Shelf of Northern Bering Sea in September 2016-2018 - Yingjie Wang; Na Liu; Lina Lin; Yan He; Bin Kong; Zhanhai Zhang (Marine Geodesy, 2020)

Resequencing 93 accessions of coffee unveils independent and parallel selection during Coffea species divergence - Lifang Huang; Xiaoyang Wang; Yunping Dong; Yuzhou Long; Chaoyun Hao; Lin Yan; Tao Shi (Plant Molecular Biology, 2020)

Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure - Jiang-shan Lian; Huan Cai; Shao-rui Hao; Xi Jin; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Shan-yan Zhang; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Interaction between serine carboxypeptidase-like protein TtGS5 and Annexin D1 in developing seeds of Triticum timopheevi - Peihong Jiang; JianSheng Gao; Junyi Mu; Luning Duan; Yunsong Gu; Shichen Han; Lin Chen; Yaxuan Li; Yueming Yan; Xiaohui Li (Journal of Applied Genetics, 2020)

Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients - Huan-Yu Meng; Xi Li; Wan-Lin Jin; Cheng-Kai Yan; Xiao-Hua Dong; Qiu Xu; Yu-Yao Peng; Zhi-Bin Li; Yi Li; Zhao-Hui Luo; Li-Qun Xu; Huan Yang (European Journal of Clinical Pharmacology, 2020)

Integrated fate assessment of aromatic amines in aerobic sewage treatment plants - Lin Jun Zhou; Zhi Yi Rong; Wen Gu; De Ling Fan; Ji Ning Liu; Li Li Shi; Yan Hua Xu; Zhi Ying Liu (Environmental Monitoring and Assessment, 2020)
The fate and exposure of chemicals in sewage treatment plants (STPs) are major considerations in risk assessment and environmental regulation. The biodegradability and removal of seven aromatic amines were systematically evaluated using a three-tiered integrated method: a standard ready biodegradability test, an aerobic sewage treatment simulation method, and model prediction. In tier 1, the seven aromatic amines were not readily biodegraded after 28 days. In adapted aerobic active sludge, 4-isopropyl aniline, 2,4-diaminotoluene, and 4-nitroaniline among them exhibited the degradation half-life time less than 20 h, the other four aromatic amines exhibited persistent with degradation half-life of > 60 h. In tier 2 of the aerobic sewage treatment simulation testing, 2,4-diaminotoluene, 4-nitroaniline, and 4-isopropylaniline demonstrated moderately to high overall removal. Hydraulic retention time (HRT) affects the removal with the optimum HRT was determined to be 12 h to 24. 2,6-Dimethyl aniline, 2-chloro-4-nitroaniline, 2,6-diethylaniline, and 3,4-dichloroaniline were not removed during the test, indicting these four aromatic amines will enter surface water and hence pose a potential risk to aquatic ecology. Considering the lack of an STP model in China for regulation purposes, in tier 3, we developed a Chinese STP (aerobic) (abbreviated as C-STP(O)) model that reflects a universal scenario for China to predict the fate. The predicted degradation, volatilization, and absorption showed a close relationship to the physicochemical properties of the chemicals, and had same tendency with tier 2 simulation test. The prediction showed that biodegradation rather than absorption or volatilization was the main removal process of aromatic amines in aerobic STP. With the combination of modified kinetics test with C-STP (O) model, the chemical fate can be more accurately predicted than using only the readily biodegradation result.

The response of warm-season precipitation extremes in China to global warming: an observational perspective from radiosonde measurements - Jianping Guo; Yan Yan; Dandan Chen; Yanmin Lv; Yi Han; Xiaoran Guo; Lin Liu; Yucong Miao; Tianmeng Chen; Ji Nie; Panmao Zhai (Climate Dynamics, 2020)

Characterization of a novel Cu-containing dissimilatory nitrite reductase from the haloarchaeon Halorussus sp. YCN54 - Jing Hou; Xiao-Yan Yang; Qin Xu; Heng-Lin Cui (Extremophiles, 2020)

Stratospheric Ozone-induced Cloud Radiative Effects on Antarctic Sea Ice - Yan Xia; Yongyun Hu; Jiping Liu; Yi Huang; Fei Xie; Jintai Lin (Advances in Atmospheric Sciences, 2020)
Recent studies demonstrate that the Antarctic Ozone Hole has important influences on Antarctic sea ice. While most of these works have focused on effects associated with atmospheric and oceanic dynamic processes caused by stratospheric ozone changes, here we show that stratospheric ozone-induced cloud radiative effects also play important roles in causing changes in Antarctic sea ice. Our simulations demonstrate that the recovery of the Antarctic Ozone Hole causes decreases in clouds over Southern Hemisphere (SH) high latitudes and increases in clouds over the SH extratropics. The decrease in clouds leads to a reduction in downward infrared radiation, especially in austral autumn. This results in cooling of the Southern Ocean surface and increasing Antarctic sea ice. Surface cooling also involves ice-albedo feedback. Increasing sea ice reflects solar radiation and causes further cooling and more increases in Antarctic sea ice.

Opportunistic bacteria use quorum sensing to disturb coral symbiotic communities and mediate the occurrence of coral bleaching - Jin Zhou; Zi‐Jun Lin; Zhong‐Hua Cai; Yan‐Hua Zeng; Jian‐Ming Zhu; Xiao‐Peng Du (Environmental Microbiology, 2020)
Summary Coral associated microorganisms, especially some opportunistic pathogens can utilize quorum‐sensing (QS) signals to affect population structure and host health. However, direct evidence about the link between coral bleaching and dysbiotic microbiomes under QS regulation was lacking. Here, using 11 opportunistic bacteria and their QS products (AHLs, acyl‐homoserine‐lactones), we exposed Pocillopora damicornis to three different treatments: test groups (A and B: mixture of AHLs‐producing bacteria and cocktail of AHLs signals respectively); control groups (C and D: group A and B with furanone added respectively); and a blank control (group E: only seawater) for 21 days. The results showed that remarkable bleaching phenomenon was observed in groups A and B. The operational taxonomic units‐sequencing analysis shown that the bacterial network interactions and communities composition were significantly changed, becoming especially enhanced in the relative abundances of Vibrio , Edwardsiella , Enterobacter , Pseudomonas , and Aeromonas . Interestingly, the control groups (C and D) were found to have a limited influence upon host microbial composition and reduced bleaching susceptibility of P. damicornis . These results indicate bleaching's initiation and progression may be caused by opportunistic bacteria of resident microbes in a process under regulation by AHLs. These findings add a new dimension to our understanding of the complexity of bleaching mechanisms from a chemoecological perspective.

The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line - Gen-Meng Yang; Lu Li; Feng-Lin Xue; Chen-Li Ma; Xiao-Feng Zeng; Yong-Na Zhao; Dong-Xian Zhang; Yang Yu; Qian-Wen Yan; Yi-Qing Zhou; Shi-Jun Hong; Li-Hua Li (Neurotoxicity Research, 2020)

The Cannabinoid Receptor Agonist WIN55,212-2 Ameliorates Hippocampal Neuronal Damage After Chronic Cerebral Hypoperfusion Possibly Through Inhibiting Oxidative Stress and ASK1-p38 Signaling - Da-Peng Wang; Qiao-Li Lv; Qi Lin; Kai Kang; Kai-Yan Jin; Jian Hai (Neurotoxicity Research, 2020)

Topological Shape Changes Weaken the Innate Defensive Response to Visual Threat in Mice - Yan Huang; Lei Li; Kun Dong; Hongsi Tang; Qingning Yang; Xianglian Jia; Yundan Liao; Wenbo Wang; Zhen Ren; Lin Chen; Liping Wang (Neuroscience Bulletin, 2020)

Targeted selective degradation of Bruton’s tyrosine kinase by PROTACs - Shaodong Liu; Yang Da; Feng Wang; Renjie Yan; Yongzhi Shu; Pei Lin; Jun Lin (Medicinal Chemistry Research, 2020)