miRNA–mRNA Integrative Analysis Reveals the Roles of miRNAs in Hypoxia-Altered Embryonic Development- and Sex Determination-Related Genes of Medaka Fish - Keng Po Lai; Nathan Yi Kan Tam; Yuelong Chen; Chi Tim Leung; Xiao Lin; Chau Fong Tsang; Yin Cheung Kwok; William Ka Fai Tse; Shuk Han Cheng; Ting Fung Chan; Richard Yuen Chong Kong (Frontiers in Marine Science, 2022)
Recent studies have shown hypoxia to be an endocrine disruptor that impairs sex differentiation and reproductive function, leading to male-biased F1 populations in fish. However, the molecular mechanisms through which hypoxia alters fish sex differentiation and therefore sex ratios remain poorly understood. In order to understand the potential role of miRNAs in mediating hypoxia-altered sex determination and differentiation in fish, we conducted small RNA sequencing and transcriptome sequencing on marine medaka ( Oryzias melastigma ) embryos that were exposed to hypoxia (2.0 ± 0.2 mg O 2 L – 1) for 40 h (encompassing a critical window of sex determination). We identified dysregulated miRNAs and mRNAs in the hypoxia-exposed embryo, and bioinformatic analysis of the integrative small RNA sequencing and transcriptome sequencing results revealed hypoxia to cause alterations of genes related to embryonic development through miRNA regulation. Importantly, we have identified miRNA-mRNA pairs that were reported to play roles in gonad development (novel miR-145-col9a3 and novel miRNA-94- arid5b), in sex hormone response (novel miRNA-210-ca2, novel miRNA-106-nr2f2, nbr-miR-29c-nr4a1, and ola-miR-92b-akr1d1), and in sex characteristic development (novel miRNA-145-mns1, nle-miR-20-sord, and ipu-miR-219b-abcc8). Our findings highlighted the possible roles of miRNA–mRNA in regulation of embryonic development and sex determination in response to hypoxic stress.

Historical Connectivity and Demography of the Ferocious Reef Crab, Eriphia ferox (Crustacea; Eriphiidae), Demonstrate That Taoyuan Algal Reef Is an Essential Population Source Along the East Taiwan Strait - Mu-Han Chen; Ya-Yi Huang; Bi-Ying Huang; Hernyi Justin Hsieh; Jen Nie Lee; Mei Lin Neo; Hironobu Fukami; Chaolun Allen Chen (Frontiers in Marine Science, 2022)
The east Taiwan Strait is largely fringed by sandy and muddy habitats. However, a massive algal reef made of crustose coralline algae has been found along the coast off Taoyuan city in northwestern Taiwan. The porous structure of Taoyuan Algal Reef harbors high abundance and diversity in marine organisms, including the ferocious reef crab, Eriphia ferox . Such a pivotal geographic location and unique ecological features make Taoyuan Algal Reef a potential stepping stone connecting biotic reefs in the east Taiwan Strait, South China Sea to the south, and even the high latitude of Japan to the north. In this study, we examined the population connectivity and historical demography of E. ferox by analyzing mitochondrial cytochrome oxidase I (COI) fragments of 317 individuals sampled from 21 localities in the northwestern Pacific. Our analyses of haplotype network and pairwise F ST comparisons revealed a lack of phylogeographical structure among E. ferox populations, implying the existence of a migration corridor connecting the South and East China Seas through the east Taiwan Strait. Multiple lines of evidence, including significant values in neutrality tests, unimodally shaped mismatch distributions, and Bayesian skyline plots elucidated the rapid population growth of E. ferox following the sea-level rise after Last Glacial Maximum (ca. 2–10 Ka). Such demographic expansion in E. ferox coincided with the time when Taoyuan Algal Reef started to build up around 7,500 years ago. Coalescent migration analyses further indicated that the large and continuous E. ferox population exclusively found in Datan Algal Reef, the heart of Taoyuan Algal Reef, was a source population exporting migrants both northward and southward to the adjacent populations. The bidirectional gene flow should be attributed to larval dispersal by ocean currents and secondary contact due to historical population expansion. Instead of serving as a stepping stone, our results support that Taoyuan Algal Reef is an essential population source for biotic reef-associated species along the east Taiwan Strait, and highlight the importance of conserving such a unique ecosystem currently threatened by anthropogenic development.

Distribution of Coomassie Blue Stainable Particles in the Pearl River Estuary, China, Insight Into the Nitrogen Cycling in Estuarine System - Cui-Ci Sun; Wei-Zhong Yue; You-Shao Wang; Wei-Hong He; Yi-Guo Hong; Fu-Lin Sun; Hao Cheng; Mei-Lin Wu; Zhao-Yu Jiang; Fei Jiao; Yu-Tu Wang (Frontiers in Marine Science, 2022)
Distributions of Coomassie Blue stainable particles (CSP), the sources and transports, as well as their implications for nitrogen biogeochemical cycles in the Pearl River estuary (PRE) were investigated during two cruises in August 2016 and January 2017. CSP color concentrations (CSP concentration determined spectrophotometrically) were 73.7–685.3 μg BSA eq L –1 [μg Bovine serum albumin (BSA) equivalent liter –1 ] in August 2016 and 100.6–396.4 μg BSA eq L –1 in January 2017, respectively. CSP concentrations were high in low-salinity waters (<5), and declined from the river to the middle estuary by 80% in the wet season and 55.6% in the dry season, respectively, then increased again in the lower estuary due to high primary production. CSP concentrations were mainly associated with chlorophyll a (Chl a ) concentration except for the turbid mixing zone, suggesting that autochthonous phytoplankton production served as the primary source of CSP in the PRE. The concentrations of nitrogen (N) as CSP in the PRE were comparable to the nitrogen content of particulate hydrolysable amino acids (PHAA). Pictures of CSP taken by microscopy and the correlation between composition of PHAA and the ratio of Chl a /CSP color showed that CSP were relatively degraded due to delivery of old terrestrial protein to river section and extensive microbial degradation during mixing at the upper and middle parts of the estuary, whereas CSP in lower estuary appeared to be more labile due to higher fresh algal production. The contribution of CSP nitrogen (CSP-N) to the particulate nitrogen (PN) pool was 34.98% in summer and 30.8% in winter. The conservative estimate of CSP-N input flux in the Pearl River Delta was about 6 × 10 6 mol N d –1 . These results suggested that CSP was a significant pool of organic nitrogen in the PRE. The study of CSP composition in terms of nitrogen provides new insight into the roles of CSP on nitrogen biogeochemical processes in the turbid and productive estuarine system.

Highly selective monoclonal antibody-based lateral flow immunoassay for visual and sensitive determination of conazole fungicides propiconazole in vegetables - Ze-Ke Xu; Jing-Nan Meng; Yi Lei; Xing-Xing Yang; Yi-Yong Yan; Hai-Hong Liu; Hong-Tao Lei; Ting-Cai Wang; Xing Shen; Zhen-Lin Xu (Food Additives & Contaminants: Part A, 2022)

β-Catenin Deletion in Regional Neural Progenitors Leads to Congenital Hydrocephalus in Mice - Lin Ma; Yanhua Du; Xiangjie Xu; Hexi Feng; Yi Hui; Nan Li; Guanyu Jiang; Xiaoqing Zhang; Xiaocui Li; Ling Liu (Neuroscience Bulletin, 2022)

Joint-Tissue Integrative Analysis Identified Hundreds of Schizophrenia Risk Genes - Yong Wu; Xiao-Lin Yu; Xiao Xiao; Ming Li; Yi Li (Molecular Neurobiology, 2022)

Identification of Novel Nonapeptides from Sipunculus nudus L. and Comparing Its ACEI Activities Mechanism by Molecular Docking - Yi Qi; Xiaoning Tang; Huan Liu; Qianxing Lin; Yingnian Lu; Hui Luo (International Journal of Peptide Research and Therapeutics, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Bioactive hydroxypropionylated glucose derivatives from Astragalus bhotanensis - Lin Qiu; Chao-Jiang Xiao; Yi Shen; Wei Xu; Xiao-Bo Liu; Xiang Dong; Bei Jiang (Natural Product Research, 2021)

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Hotter and drier climate made the Mediterranean Europe and Northern Africa region a shrubbier landscape - Wei Fang; Chuixiang Yi; Deliang Chen; Peipei Xu; George Hendrey; Nir Krakauer; Katherine Jensen; Shan Gao; Zihan Lin; Gabriella Lam; Qin Zhang; Tao Zhou (Oecologia, 2021)

Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum–Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats - Kokwin Ooi; Li Hu; Yi Feng; Chenzhi Han; Xiaorong Ren; Xinyi Qian; Haofeng Huang; Sijia Chen; Qi Shi; Hong Lin; Jijiang Wang; Danian Zhu; et al. (Molecular Neurobiology, 2021)

Association between exposure to road traffic noise and hearing impairment: a case-control study - Tang-Chuan Wang; Ta-Yuan Chang; Richard S. Tyler; Bing-Fang Hwang; Yi-Hung Chen; Che-Ming Wu; Chiu-Shong Liu; Kuang-Chao Chen; Chia-Der Lin; Ming-Hsui Tsai (Journal of Environmental Health Science and Engineering, 2021)

Feasibility and utility of facemask sampling in the detection of SARS-CoV-2 during an ongoing pandemic - Dorothy Hui Lin Ng; Mei Yi Sim; Hong Hong Huang; Jean Xiang Ying Sim; Jenny Guek Hong Low; Jay Kheng Sit Lim (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

External evaluation of published population pharmacokinetic models of polymyxin B - Ya-qian Li; Kai-feng Chen; Jun-jie Ding; Hong-yi Tan; Nan Yang; Ya-qi Lin; Cui-fang Wu; Yue-liang Xie; Guo-ping Yang; Jing-Jing Liu; Qi Pei (European Journal of Clinical Pharmacology, 2021)

Does the smart city policy promote the green growth of the urban economy? Evidence from China - Yu Qian; Jun Liu; Zhonghua Cheng; Jeffrey Yi-Lin Forrest (Environmental Science and Pollution Research, 2021)

The r-X1 deletion induces terminal deficiencies in the maize B chromosome - Yen-Hua Huang; Tzu-Che Lin; Wan-Yi Chiou; Ya-Ming Cheng (Chromosome Research, 2021)

Genetic Diversity and Population Structure of Gynaephora qinghaiensis in Yushu Prefecture, Qinghai Province Based on the Mitochondrial COI Gene - Haizhen Wang; Xin Zhong; Huafeng Lin; Shaosong Li; Jiequn Yi; Guren Zhang; Xin Liu; Li Gu (Biochemical Genetics, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

The policy effects and influence mechanism of China’s carbon emissions trading scheme - Chen Wang; Yi Shi; Lin Zhang; Xin Zhao; Hungxin Chen (Air Quality, Atmosphere & Health, 2021)

A New Instrumental Array in Sichuan, China, to Monitor Vibrations and Perturbations of the Lithosphere, Atmosphere, and Ionosphere - Chieh-Hung Chen; Yang-Yi Sun; Kai Lin; Chen Zhou; Rui Xu; Haiyin Qing; Yongxin Gao; Tao Chen; Fei Wang; Huaizhong Yu; Peng Han; Chi-Chia Tang; et al. (Surveys in Geophysics, 2021)

The role of mechanical harvesting on the recession of aquatic vegetation under an extreme water level increase in a eutrophic shallow lake - Changtao Yang; Jing Nan; Jianhua Li; Yi Lin; Jie Yu; Jianbin Wu; Xiaobing Shen (Environmental Science and Pollution Research, 2021)

Paternal exposure to microcystin-LR induces fetal growth restriction partially through inhibiting cell proliferation and vascular development in placental labyrinth - Lan Gao; An-Qi Cui; Jing Wang; Jing Chen; Xiao-Yi Zhang; Zhi-Jing Lin; Yuan-Hua Chen; Cheng Zhang; Hua Wang; De-Xiang Xu (Environmental Science and Pollution Research, 2021)

Temporal stability analysis of soil moisture along a coniferous forest hillslope with subtropical monsoon climate in southwest China - Yu-shi Bai; Mu-xing Liu; Jun Yi; Hai-lin Zhang (Journal of Mountain Science, 2021)

Streptococcus vaginalis sp. nov., a novel bacterial species isolated from vaginal swabs of a pregnant woman with diabetes - An-Shine Chao; Chiao-Yun Lin; Angel Chao; Yun-Shien Lee; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Yi-Sheng Chen (Archives of Microbiology, 2021)

The Decision Strategies of Adolescents with Different Emotional Stabilities in Unfair Situations - Yajing Si; Lin Jiang; Chanlin Yi; Qi Zhang; Cunbo Li; Jing Yu; Peiyang Li; Qiang Liu; Feng Wan; Fali Li; Dezhong Yao; Peng Xu (Neuroscience Bulletin, 2021)

Three new species of Cylindrobasidium (Physalacriaceae, Agaricales) from East Asia - Yi-Chung Lin; Chia-Ling Wei; Chi-Yu Chen; Che-Chih Chen; Sheng-Hua Wu (Mycological Progress, 2021)

Depression Augments Plasma APOA4 without Changes of Plasma Lipids and Glucose in Female Adolescents Carrying G Allele of APOA4 rs5104 - Qi Wei Guo; Yan Jun Si; Yi Lin Shen; Xu Chen; Mei Yang; Ding Zhi Fang; Jia Lin (Journal of Molecular Neuroscience, 2021)

Dynamics of antibiotic resistance and its association with bacterial community in a drinking water treatment plant and the residential area - Fu-Yi Huang; Qing-Lin Chen; Xian Zhang; Roy Neilson; Jian-Qiang Su; Shu-Yi-Dan Zhou (Environmental Science and Pollution Research, 2021)

The impact of green credit policy on energy efficient utilization in China - Xiaowei Ma; Weiwei Ma; Lin Zhang; Yi Shi; Yuping Shang; Huangxin Chen (Environmental Science and Pollution Research, 2021)

A dynamical pathway bridging African biomass burning and Asian summer monsoon - Dianbin Cao; Tae-Won Park; Yongjia Song; Yuhang Wang; Zhenyu You; Yanluan Lin; Yi Deng (Climate Dynamics, 2021)

Shared and specific patterns of structural and functional thalamo-frontal disturbances in manic and euthymic pediatric bipolar disorder - Yi-Bing Guo; Wei-Jia Gao; Zhi-Liang Long; Wei-Fang Cao; Dong Cui; Yong-Xin Guo; Qing Jiao; Jian-Feng Qiu; Lin-Yan Su; Guang-Ming Lu (Brain Imaging and Behavior, 2021)
Bipolar disorder (BD) is clinically defined by alternating depressive and manic episodes with a separated period of euthymia. Thalamo-frontal loop plays vital role in psychotic symptoms, altered motor control and executive difficulties in BD. It remains unclear that structural and functional alterations of thalamo-frontal loop among the different mood states in BD, especially in pediatric BD(PBD). Twenty manic PBD (mPBD), 20 euthymic PBD (ePBD) and 19 healthy controls (HCs) were included in the study. By analyzing the T1 images and fMRI signals, thalamus volume and frontal grey matter cortical thickness were tested, and functional connectivity (FC) between bilateral thalamus and frontal cortex was calculated. Relationship between clinical indices and thalamo-frontal FC was also evaluated in mPBD and ePBD adolescents. Compared to HCs, the cortical thickness of left middle frontal gyrus (MFG), bilateral superior frontal gyrus (SFG) was significantly decreased in both mPBD and ePBD patients, and volume of left thalamus and cortical thickness of right MFG significantly decreased in mPBD patients. Compared to that of the HCs and ePBD subjects, thalamo-frontal hyperconnectivity with MFG was found in mPBD, and compared with that of HCs, thalamo-frontal hypoconnectivity with precentral gyrus/SFG was found in ePBD. In ePBD patients, episode times positively correlated with FC values between thalamus and precentral gyrus. The findings of the present study demonstrate detailed knowledge regarding shared and specific structural and functional disruption in thalamo-frontal loop in mPBD and ePBD subjects. Thalamo-frontal abnormalities reported in adult BD subjects were also observed in adolescent BD patients, and thalamo-frontal dysfunction may be a crucial treatment target in BD.

Exercise renovates H2S and Nrf2-related antioxidant pathways to suppress apoptosis in the natural ageing process of male rat cortex - Jing-Ying Lin; Tsung-Jung Ho; Bruce Chi-Kang Tsai; Chien-Yi Chiang; Hui-Chuan Kao; Wei-Wen Kuo; Ray-Jade Chen; Vijaya Padma Viswanadha; Chi-Wen Huang; Chih-Yang Huang (Biogerontology, 2021)

Identification of TYROBP and FCER1G as Key Genes with Prognostic Value in Clear Cell Renal Cell Carcinoma by Bioinformatics Analysis - Licheng Wang; Yun Lin; Yi Yuan; Fei Liu; Kai Sun (Biochemical Genetics, 2021)

Correction to: A failure case study of tunnel water inrush source identified by statistical analysis model - Li-Gang Yuan; Xiao-Li Li; Xin Li; Yi-Lin Yu; Li-Guang Chen; Xian-Pan Xu; Xiang Wang (Arabian Journal of Geosciences, 2021)

Effects of Fatigue on Inter-joint Coordination in Ballet Dancers During a Ballet Jumping Movement (petit échappé sauté) - Chai-Wei Lin; Jeng-Feng Yang; Yi-An Chen; Cheng-Feng Lin (Journal of Medical and Biological Engineering, 2021)

Experimental study on integrated and autonomous conductivity-temperature-depth (CTD) sensor applied for underwater glider - Bin Lv; Hai-lin Liu; Yi-fan Hu; Cheng-xuan Wu; Jie Liu; Hai-jing He; Jie Chen; Jian Yuan; Zhao-wen Zhang; Lin Cao; Hui Li (Marine Georesources & Geotechnology, 2021)

Plant multiscale networks: charting plant connectivity by multi-level analysis and imaging techniques - Xi Zhang; Yi Man; Xiaohong Zhuang; Jinbo Shen; Yi Zhang; Yaning Cui; Meng Yu; Jingjing Xing; Guangchao Wang; Na Lian; Zijian Hu; Lingyu Ma; et al. (Science China Life Sciences, 2021)

Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson’s disease: a systematic review and meta-analysis - De-Qi Jiang; Qing-Min Zang; Li-Lin Jiang; Yan Wang; Ming-Xing Li; Jing-Yi Qiao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Research progress on the impact of flood discharge atomization on the ecological environment - Li Lin; Yi Li; Wei Zhang; Zhuo Huang; Duan Chen; Min Liu; John Crittenden (Natural Hazards, 2021)

Applying Artificial Intelligence (AI) Techniques to Implement a Practical Smart Cage Aquaculture Management System - Chung-Cheng Chang; Jung-Hua Wang; Jenq-Lang Wu; Yi-Zeng Hsieh; Tzong-Dar Wu; Shyi-Chy Cheng; Chin-Chun Chang; Jih-Gau Juang; Chyng-Hwa Liou; Te-Hua Hsu; Yii-Shing Huang; Cheng-Ting Huang; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose This paper presents our team’s results to establish an AIoT smart cage culture management system. Methods According to the built system, the farmed field information is transmitted to the data platform of Ocean Cloud, and all collected data and analysis results can be applied to the cage culture field after the bigdata analysis. Results This management system successfully integrates AI and IoT technologies and is applied in cage culture. Using underwater biological analysis images and AI feeding as examples, this paper explains how the system integrates AI and IoT into a feasible framework that can constantly acquire information about the health status of fish, survival rate of fish, as well as the feed residuals. Conclusion The results of our research enable the aquaculture operators or owners to efficiently reduce the feed residual, monitor the growth of fish, and increase fish survival rate, thereby increasing the feed conversion rate.

Pulmonary toxicity of actual alveolar deposition concentrations of ultrafine particulate matters in human normal bronchial epithelial cell - Chia-Hua Lin; Shih-Chun Candice Lung; Yi-Chun Chen; Lung-Chun Wang (Environmental Science and Pollution Research, 2021)

High-throughput sequencing clarifies the spatial structures of microbial communities in cadmium-polluted rice soils - Li Song; Zhenzhi Pan; Yi Dai; Lin Chen; Li Zhang; Qilin Liao; Xiezhi Yu; Hongyan Guo; Guisheng Zhou (Environmental Science and Pollution Research, 2021)

Viable and Heat-Killed Probiotic Strains Improve Oral Immunity by Elevating the IgA Concentration in the Oral Mucosa - Wen-Yang Lin; Yi-Wei Kuo; Ching-Wei Chen; Yu-Fen Huang; Chen-Hung Hsu; Jia-Hung Lin; Cheng-Ruei Liu; Jui-Fen Chen; Ko-Chiang Hsia; Hsieh-Hsun Ho (Current Microbiology, 2021)
Oral-nasal mucosal immunity plays a crucial role in protecting the body against bacterial and viral invasion. Safe probiotic products have been used to enhance human immunity and oral health. In this study, we verified the beneficial effects of mixed viable probiotic tablets, consisting of Lactobacillus salivarius subsp. salicinius AP-32, Bifidobacterium animalis subsp. lactis CP-9, and Lactobacillus paracasei ET-66, and heat-killed probiotic tablets, consisting of L. salivarius subsp. salicinius AP-32 and L. paracasei ET-66, on oral immunity among 45 healthy participants. Participants were randomly divided into viable probiotic, heat-killed probiotic, and placebo groups. The administration of treatment lasted for 4 weeks. Saliva samples were collected at Weeks 0, 2, 4, and 6, and Lactobacillus , Bifidobacterium and Streptococcus mutans populations and IgA concentration were measured. IgA concentrations, levels of TGF-beta and IL-10 in PBMCs cells were quantified by ELISA method. Results showed that salivary IgA levels were significantly increased on administration of both the viable (119.30 ± 12.63%, *** P < 0.001) and heat-killed (116.78 ± 12.28%, *** P < 0.001) probiotics for 4 weeks. Among three probiotic strains, AP-32 would effectively increase the levels of TGF-beta and IL-10 in PBMCs. The oral pathogen Streptococcus mutans was significantly reduced on viable probiotic tablet administration (49.60 ± 31.01%, *** P < 0.001). The in vitro antibacterial test confirmed that viable probiotics effectively limited the survival rate of oral pathogens. Thus, this clinical pilot study demonstrated that oral probiotic tablets both in viable form or heat-killed form could exert beneficial effects on oral immunity via IL-10, TGB-beta mediated IgA secretion. The effective dosage of viable probiotic content in the oral tablet was 10 9 CFUs/g and the heat-killed oral tablet was 1 × 10 10 cells/g.

Dating deformation using sheared leucogranite: temporal constraints by 40Ar/39Ar thermochronology for the Mae Ping shear zone, NW Thailand - Yu-Ling Lin; Tung-Yi Lee; Ching-Hua Lo; Sarah C. Sherlock; Yoshiyuki Iizuka; Tadashi Usuki; Long Xiang Quek; Punya Charusiri (Contributions to Mineralogy and Petrology, 2021)

Rock slope stability analysis considering the effect of locked section - Yi Tang; Hang Lin; Yixian Wang; Yanlin Zhao (Bulletin of Engineering Geology and the Environment, 2021)

Application of the modified cytosine base-editing in the cultured cells of bama minipig - Jia-sheng Pan; Zi-sheng Lin; Jian-cong Wen; Jian-feng Guo; Xia-hui Wu; Ying-ying Liu; Wen-jun Lai; Qi-ying Liang; Yong-shi Xie; Yi-rou Chen; Yi-hong Chen; Ai-fen Yan; et al. (Biotechnology Letters, 2021)

Cortisol and glucocorticoid receptor 2 regulate acid secretion in medaka (Oryzias latipes) larvae - Chia-Hao Lin; Huei-Jyun Hu; Hsin-Ju Chuang; Yi-Ling Tsou; Pung-Pung Hwang (Journal of Comparative Physiology B, 2021)

Flavobacterium difficile sp. nov., isolated from a freshwater waterfall - Wen-Ming Chen; Ya-Xiu You; Chiu-Chung Young; Shih-Yao Lin; Shih-Yi Sheu (Archives of Microbiology, 2021)

A failure case study of tunnel water inrush source identified by statistical analysis model - Li-Gang Yuan; Xiao-Li Li; Xin Li; Yi-Lin Yu; Li-Gang Chen; Xian-Pan Xu; Xiang Wang (Arabian Journal of Geosciences, 2021)

Taxonomic description of Pseudomonas rhizovicinus sp. nov., isolated from the rhizosphere of a desert shrub Haloxylon ammodendron - Ao-Lei He; Hui-Ru Li; Hui-Ping Li; Jing-Yi Gou; Jia Chen; Qi Zhao; Jin-Lin Zhang (Antonie van Leeuwenhoek, 2021)

Energy consumption, air pollution, and public health in China: based on the Two-Stage Dynamic Undesirable DEA model - Hang Lin; Huangxin Chen; Lin Zhang; Youjia Luo; Yi Shi; Wenjie Zou (Air Quality, Atmosphere & Health, 2021)

The Significant Role of Radiosonde-measured Cloud-base Height in the Estimation of Cloud Radiative Forcing - Hui Xu; Jianping Guo; Jian Li; Lin Liu; Tianmeng Chen; Xiaoran Guo; Yanmin Lyu; Ding Wang; Yi Han; Qi Chen; Yong Zhang (Advances in Atmospheric Sciences, 2021)

Comparative Analysis of Two Approaches for Correcting the Systematic Ocean Temperature Bias of CAS-ESM-C - Mengjiao Du; Fei Zheng; Jiang Zhu; Renping Lin; Kan Yi (Journal of Marine Science and Engineering, 2021)
Currently, several ocean data assimilation methods have been adopted to increase the performance of air–sea coupled models, but inconsistent adjustments between the sea temperature with other oceanic fields can be introduced. In the coupled model CAS-ESM-C, inconsistent adjustments for ocean currents commonly occur in the tropical western Pacific and the eastern Indian Ocean. To overcome this problem, a new ensemble-based bias correction approach—a simple modification of the Ensemble Optimal Interpolation (EnOI) approach for multi-variable into a direct approach for a single variable—is proposed to minimize the model biases. Compared with the EnOI approach, this new approach can effectively avoid inconsistent adjustments. Meanwhile, the comparisons suggest that inconsistent adjustment mainly results from the unreasonable correlations between temperature and ocean current in the background matrix. In addition, the ocean current can be directly corrected in the EnOI approach, which can additionally generate biases for the upper ocean. These induced ocean biases can produce unreasonable ocean heat sinking and heat storage in the tropical western Pacific. It will generate incorrect ocean heat transmission toward the east, further amplifying the inconsistency introduced through the tropical air–sea interaction process.

Elevated pCO2 Impedes Succession of Phytoplankton Community From Diatoms to Dinoflagellates Along With Increased Abundance of Viruses and Bacteria - Ruiping Huang; Jiazhen Sun; Yunlan Yang; Xiaowen Jiang; Zhen Wang; Xue Song; Tifeng Wang; Di Zhang; He Li; Xiangqi Yi; Shouchang Chen; Nanou Bao; et al. (Frontiers in Marine Science, 2021)
Eutrophic coastal regions are highly productive and greatly influenced by human activities. Primary production supporting the coastal ecosystems is supposed to be affected by progressive ocean acidification driven by increasing CO 2 emissions. In order to investigate the effects of high p CO 2 (HC) on eutrophic plankton community structure and ecological functions, we employed 9 mesocosms and carried out an experiment under ambient (∼410 ppmv) and future high (1000 ppmv) atmospheric p CO 2 conditions, using in situ plankton community in Wuyuan Bay, East China Sea. Our results showed that HC along with natural seawater temperature rise significantly boosted biomass of diatoms with decreased abundance of dinoflagellates in the late stage of the experiment, demonstrating that HC repressed the succession from diatoms to dinoflagellates, a phenomenon observed during algal blooms in the East China Sea. HC did not significantly influence the primary production or biogenic silica contents of the phytoplankton assemblages. However, the HC treatments increased the abundance of viruses and heterotrophic bacteria, reflecting a refueling of nutrients for phytoplankton growth from virus-mediated cell lysis and bacterial degradation of organic matters. Conclusively, our results suggest that increasing CO 2 concentrations can modulate plankton structure including the succession of phytoplankton community and the abundance of viruses and bacteria in eutrophic coastal waters, which may lead to altered biogeochemical cycles of carbon and nutrients.

Proteomics provides individualized options of precision medicine for patients with gastric cancer - Wenwen Huang; Dongdong Zhan; Yazhuo Li; Nairen Zheng; Xin Wei; Bin Bai; Kecheng Zhang; Mingwei Liu; Xuefei Zhao; Xiaotian Ni; Xia Xia; Jinwen Shi; et al. (Science China Life Sciences, 2021)

The major photoprotective role of anthocyanins in leaves of Arabidopsis thaliana under long-term high light treatment: antioxidant or light attenuator? - Xiao-Ting Zheng; Zheng-Chao Yu; Jun-Wei Tang; Min-Ling Cai; Yi-Lin Chen; Cheng-Wei Yang; Wah Soon Chow; Chang-Lian Peng (Photosynthesis Research, 2021)

Epididymal initial segment-specific Cre recombinase activity in Lcn8-Cre knock-in mice - Qian-qian Gong; Zhi-lin Dou; Xiao Wang; Ke-yi Zhang; Hao Chen; Jian-gang Gao; Xiao-yang Sun (Molecular Biology Reports, 2021)

Combination of XGBoost Analysis and Rule-Based Method for Intrapartum Cardiotocograph Classification - Pao-Lin Kuo; Lim Bee Yen; Yi-Chun Du; Po-Fan Chen; Pei-Yin Tsai (Journal of Medical and Biological Engineering, 2021)

Characteristics of bacterial community and ARGs profile in engineered goldfish tanks with stresses of sulfanilamide and copper - Benjamin Makimilua Tiimub; Zhen-chao Zhou; Lin Zhu; Yang Liu; Xin-Yi Shuai; Lan Xu; Christophe’ Niyungeko; Ling-Xuan Meng; Yu-Jie Sun; Hong Chen (Environmental Science and Pollution Research, 2021)

Ecological treatment technology for agricultural non-point source pollution in remote rural areas of China - Xuesong Yi; Dexin Lin; Jiahui Li; Jie Zeng; Dexin Wang; Fei Yang (Environmental Science and Pollution Research, 2021)

Extreme climate changes over three major river basins in China as seen in CMIP5 and CMIP6 - Xian Zhu; Shao-Yi Lee; Xiaohang Wen; Zhenming Ji; Lei Lin; Zhigang Wei; Zhiyuan Zheng; Danya Xu; Wenjie Dong (Climate Dynamics, 2021)

Genetic changes and evolutionary analysis of canine circovirus - Lin Wang; Yifan li; Zhiyuan Guo; Ying Yi; Han Zhang; Haikun Shangguan; Chengshi Huang; Junwei Ge (Archives of Virology, 2021)

Aestuariibaculum sediminum sp. nov., a marine bacterium isolated from a tidal flat in Zhoushan - Zhi-Cheng Wu; Xin-Yin Zhang; Cong Sun; Lin Xu; Ge-Yi Fu; Xue-Wei Xu (Archives of Microbiology, 2021)

Heavy Rainfall Events Following the Dry Season Elevate Metal Contamination in Mining-Impacted Rivers: A Case Study of Wenyu River, Qinling, China - Dong Chen; Yi-ping Chen; Yishan Lin (Archives of Environmental Contamination and Toxicology, 2021)

Distribution, Temporal Change, and Conservation Status of Tropical Seagrass Beds in Southeast Asia: 2000–2020 - Kenji Sudo; T. E. Angela L. Quiros; Anchana Prathep; Cao Van Luong; Hsing-Juh Lin; Japar Sidik Bujang; Jillian Lean Sim Ooi; Miguel D. Fortes; Muta Harah Zakaria; Siti Maryam Yaakub; Yi Mei Tan; Xiaoping Huang; et al. (Frontiers in Marine Science, 2021)
Although Southeast Asia is a hotspot of global seagrass diversity, there are considerable information gaps in the distribution of seagrass beds. Broad-scale seagrass distribution has not been updated in the global seagrass database by UNEP-WCMC since 2000, although studies on seagrasses have been undertaken intensively in each region. Here we analyze the recent distribution of tropical seagrass beds, their temporal changes, causes of decline and conservation status in Southeast Asia (plus southern mainland China, Taiwan and Ryukyu Island of Japan) using data collected after 2000. Based on the 195 literature published since 2000, we identified 1,259 point data and 1,461 polygon data showing the distribution of seagrass beds. A large discrepancy was found in the seagrass bed distribution between our updated data and the UNEP-WCMC database, mostly due to inaccurate and low resolution location information in the latter. Temporal changes in seagrass bed area analyzed for 68 sites in nine countries/regions demonstrated that more than 60% of seagrass beds declined at an average rate of 10.9% year –1 , whereas 20% of beds increased at an average rate of 8.1% year –1 , leading to an overall average decline of 4.7% year –1 . Various types of human-induced threats were reported as causes for the decline, including coastal development, fisheries/aquaculture, and natural factors such as typhoons and tsunamis. The percentage of seagrass beds covered with existing marine protected areas (MPAs) varied greatly among countries/regions, from less than 1% in Brunei Darussalam and Singapore to 100% in southern Japan. However, the degree of conservation regulation was not sufficient even in regions with higher MPA coverage. The percentage of seagrass beds within EBSAs (Ecologically and Biologically Significant Area determined by the Convention of Biological Diversity) was higher than that within MPAs because EBSAs cover a greater area than MPAs. Therefore, designating EBSAs as legally effective MPAs can greatly improve the conservation status of seagrass beds in Southeast Asia.

Comparative analysis of sRNAs, degradome and transcriptomics in sweet sorghum reveals the regulatory roles of miRNAs in Cd accumulation and tolerance - Weitao Jia; Kangqi Lin; Tengxue Lou; Juanjuan Feng; Sulian Lv; Ping Jiang; Ze Yi; Xuan Zhang; Duoliya Wang; Zijing Guo; Yetao Tang; Rongliang Qiu; et al. (Planta, 2021)

Toll-like receptor 3 (TLR3) regulation mechanisms and roles in antiviral innate immune responses - Yujuan Chen; Junhong Lin; Yao Zhao; Xianping Ma; Huashan Yi (Journal of Zhejiang University-SCIENCE B, 2021)

Failure mechanism of a slow-moving landslide on September 27, 2020, in Chang Nong Village, Guangxi, China - Jiaming Zhang; Zhi Zhou; Feng Lin; Qinggang Yang; Yi Luo (Landslides, 2021)

Human papillomavirus prevalence among men who have sex with men in China: a systematic review and meta-analysis - Yiguo Zhou; Yi-Fan Lin; Lei Gao; Jianghong Dai; Ganfeng Luo; Lanying Li; Tanwei Yuan; Peiyang Li; Yuewei Zhan; Yanxiao Gao; Huachun Zou (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Investigating the use of environmental tableware based on the theory of planned behavior - Jui-Che Tu; Yu-Yin Chen; Yi-Lin Lee; Xiao-Lin Wang (Environment, Development and Sustainability, 2021)

3D-var assimilation of GTS observation with the gravity wave drag scheme improves summer high resolution climate simulation over the Tibetan Plateau - Qian Xie; Yi Yang; Xiaobin Qiu; Yuanyuan Ma; Anwei Lai; Erliang Lin; Xiaoping Mai (Climate Dynamics, 2021)

Assessment of ecological importance of the Qinghai-Tibet Plateau based on ecosystem service flows - Zi-yan Lin; Yi Xiao; Zhi-yun Ouyang (Journal of Mountain Science, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

Detection of Vestibular Schwannoma on Triple-parametric Magnetic Resonance Images Using Convolutional Neural Networks - Tzu-Hsuan Huang; Wei-Kai Lee; Chih-Chun Wu; Cheng-Chia Lee; Chia-Feng Lu; Huai-Che Yang; Chun-Yi Lin; Wen-Yuh Chung; Po-Shan Wang; Yen-Ling Chen; Hsiu-Mei Wu; Wan-You Guo; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose The first step in typical treatment of vestibular schwannoma (VS) is to localize the tumor region, which is time-consuming and subjective because it relies on repeatedly reviewing different parametric magnetic resonance (MR) images. A reliable, automatic VS detection method can streamline the process. Methods A convolutional neural network architecture, namely YOLO-v2 with a residual network as a backbone, was used to detect VS tumors from MR images. To heighten performance, T1-weighted–contrast-enhanced, T2-weighted, and T1-weighted images were combined into triple-channel images for feature learning. The triple-channel images were cropped into three sizes to serve as input images of YOLO-v2. The VS detection effectiveness levels were evaluated for two backbone residual networks that downsampled the inputs by 16 and 32. Results The results demonstrated the VS detection capability of YOLO-v2 with a residual network as a backbone model. The average precision was 0.7953 for a model with 416 × 416-pixel input images and 16 instances of downsampling, when both the thresholds of confidence score and intersection-over-union were set to 0.5. In addition, under an appropriate threshold of confidence score, a high average precision, namely 0.8171, was attained by using a model with 448 × 448-pixel input images and 16 instances of downsampling. Conclusion We demonstrated successful VS tumor detection by using a YOLO-v2 with a residual network as a backbone model on resized triple-parametric MR images. The results indicated the influence of image size, downsampling strategy, and confidence score threshold on VS tumor detection.

Naringin Ameliorates Haloperidol-Induced Neurotoxicity and Orofacial Dyskinesia in a Rat Model of Human Tardive Dyskinesia - Mao-Hsien Wang; Chih-Chuan Yang; Hsiang-Chien Tseng; Chih-Hsiang Fang; Yi-Wen Lin; Hung-Sheng Soung (Neurotoxicity Research, 2021)

Biochar Alters Inorganic Phosphorus Fractions in Tobacco-growing Soil - Wenli Zhang; Caibin Li; Guitong Li; Qimei Lin; Xiaorong Zhao; Yi He; Yanxiang Liu; Zhenbao Luo (Journal of Soil Science and Plant Nutrition, 2021)

Water Inrush Risk Assessment of Coal Floor After CBM Development Based on the Fractal-AHP-Vulnerlability Index Method - Jian-lin Li; Shu-wei Wang; Yan Wang; Xin-yi Wang; Xiong-xiong Wang (Geotechnical and Geological Engineering, 2021)

Effect of dermal phthalate levels on lung function tests in residential area near a petrochemical complex - Chih-Wen Wang; Szu-Chia Chen; Da-Wei Wu; Huang-Chi Chen; Hung-Hsun Lin; Hung Su; Jen-taie Shiea; Wen-Yi Lin; Chih-Hsing Hung; Chao-Hung Kuo (Environmental Science and Pollution Research, 2021)

LncRNA RNCR3 promotes endothelial cell proliferation and inflammatory cytokine secretion via regulating miR-185-5p/cyclin D2 axis - Quanlong Hong; Lin Ling; Wenli Huang; Yilan Liu; Yafen Zhuo; Zhenzhen Hong; Bing Wu; Yi Zhang (Environmental Science and Pollution Research, 2021)

Nanoselenium and Selenium Yeast Have Minimal Differences on Egg Production and Se Deposition in Laying Hens - Tian-Tian Meng; Xue Lin; Chun-Yan Xie; Jian-Hua He; Yang-Kui Xiang; Yi-Qiang Huang; Xin Wu (Biological Trace Element Research, 2021)

A dye combination for the staining of pollen coat and pollen wall - Xin-Lei Jia; Jing-Shi Xue; Fang Zhang; Chi Yao; Shi-Yi Shen; Chang-Xu Sui; Yu-Jia Peng; Qin-Lin Xu; Yi-Feng Feng; Wen-Jing Hu; Ping Xu; Zhong-Nan Yang (Plant Reproduction, 2021)

First report of cucurbit chlorotic yellows virus infecting melon, watermelon and wild melon in the Philippines - Hsin-Yi Chang; Li-Cheng Chen; Chung-Cheng Lin; Wen-Shi Tsai (Journal of Plant Pathology, 2021)

Efficient electrokinetic remediation of heavy metals from MSWI fly ash using approaching anode integrated with permeable reactive barrier - Huilin Li; Yi Zheng; Lin Yu; Huirong Lin; Manli Zhang; Binquan Jiao; YanChyuan Shiau; Dongwei Li (Environmental Science and Pollution Research, 2021)

Dynamics of the spatiotemporal morphology of Mei-yu fronts: an initial survey - Yang Hu; Yi Deng; Yanluan Lin; Zhimin Zhou; Chunguang Cui; Xiquan Dong (Climate Dynamics, 2021)
Mei-yu fronts are often accompanied with prominent diabatic heating due to the development of frontal clouds and rain bands. The direct effect and relative importance of diabatic heating on the spatiotemporal morphology of Mei-yu fronts however remain unclear. Here a new frontogenesis function is derived to isolate the effect of diabatic heating and this function is then applied to the latest high resolution reanalysis product ERA5 to conduct an initial survey of dynamic and thermodynamic processes driving the intensity and structure evolutions of three typical Mei-yu fronts. It is found that the direct effect of latent heating (moisture depletion) is always frontogenetical (frontolytical) in the pre-frontal and frontal zone throughout the lifecycle of the front with latent heating (moisture depletion) in general dominates the front intensification (dissipation). Tilting is another critical process that turns the vertical gradient of equivalent potential temperature into horizontal gradient leading to frontogenesis during the front development stage, and, after the release of convective instability ahead of the front, flattens the front surface leading to frontolysis during the front decaying stage. Therefore titling maintains consistently positive contributions to the evolution of a Mei-yu front and its importance depends highly on the convective intensity near the front. The deformation effect appears frontogenetical but carries a much smaller weight compared to diabatic heating, moisture depletion and tilting. The structure evolutions of the three Mei-yu fronts studied here exhibit two distinct patterns: “bending and breaking”, and “moving and rotating”. Both patterns are dominated by the front propagation (i.e., frontogenesis through air parcels), further highlighting the critical roles played by diabatic heating, moisture depletion and titling in determining the spatiotemporal characteristics of Mei-yu fronts. As these three processes are all closely tied to updrafts, clouds and precipitation near the fronts, improved representations of clouds and convection are needed to accurately depict their feedbacks to frontal evolutions and ultimately achieve better predictions of heavy rainfall and floods associated with Mei-yu fronts.

Genome sequencing and functional annotation of Bacillus sp. strain BS-Z15 isolated from cotton rhizosphere soil having antagonistic activity against Verticillium dahliae - Zhong-Yi Chen; Xieerwanimu Abuduaini; Nuramina Mamat; Qi-Lin Yang; Meng-Jun Wu; Xin-Rui Lin; Ru Wang; Rong-Rong Lin; Wei-Jun Zeng; Huan-Chen Ning; He-Ping Zhao; Jin-Yu Li; et al. (Archives of Microbiology, 2021)

Effects of indole acetic acid on the growth and selenium absorption characteristics of Cyphomandra betacea seedlings - Yunmin Huan; Liu Yang; Qin Liu; Lijin Lin; Ming’an Liao; Zhihui Wang; Dong Liang; Hui Xia; Yi Tang; Xiulan Lv; Jin Wang (Acta Physiologiae Plantarum, 2021)

Microbial transformation of distinct exogenous substrates into analogous composition of recalcitrant dissolved organic matter - Jie Lian; Xiaoxuan Zheng; Xiaocun Zhuo; Yi‐Lung Chen; Chen He; Qiang Zheng; Ta‐Hui Lin; Jia Sun; Weidong Guo; Quan Shi; Nianzhi Jiao; Ruanhong Cai (Environmental Microbiology, 2021)
Summary Oceanic dissolved organic matter (DOM) comprises a complex molecular mixture which is typically refractory and homogenous in the deep layers of the ocean. Though the refractory nature of deep‐sea DOM is increasingly attributed to microbial metabolism, it remains unexplored whether ubiquitous microbial metabolism of distinct carbon substrates could lead to similar molecular composition of refractory DOM. Here, we conducted microbial incubation experiments using four typically bioavailable substrates (L‐alanine, trehalose, sediment DOM extract, and diatom lysate) to investigate how exogenous substrates are transformed by a natural microbial assemblage. The results showed that although each‐substrate‐amendment induced different changes in the initial microbial assemblage and the amended substrates were almost depleted after 90 days of dark incubation, the bacterial community compositions became similar in all incubations on day 90. Correspondingly, revealed by ultra‐high resolution mass spectrometry, molecular composition of DOM in all incubations became compositionally consistent with recalcitrant DOM and similar toward that of DOM from the deep‐sea. These results indicate that while the composition of natural microbial communities can shift with substrate exposures, long‐term microbial transformation of distinct substrates can ultimately lead to a similar refractory DOM composition. These findings provide an explanation for the homogeneous and refractory features of deep‐sea DOM.

Phenolic constituents from the fresh pericarps of Juglans sigillata - Yi Lin; Jingjing Liang; Xiaogang Peng; Hanli Ruan (Natural Product Research, 2021)

The Effects of Installation on the Elastic Stiffness Coefficients of Spudcan Foundations - Wen-Long Lin; Zhen Wang; Fei Liu; Jiang-Tao Yi (Journal of Marine Science and Engineering, 2021)
Subjected to pre-load, spudcan foundations, widely utilized to support offshore jack-up rigs, may penetrate in a few diameters into soft clays before mobilizing sufficient resistance from soil. While its stress–strain behavior is known to be affected by the embedment condition and soil backflow, the small-strain calculation with wished-in-place assumption was previously adopted to analyze its elastic stiffness coefficients. This study takes advantage of a recently developed dual-stage Eulerian–Lagrangian (DSEL) technique to re-evaluate the elastic stiffness coefficients of spudcans after realistically modelling the deep, continuous spudcan penetration. A numerical parametric exercise is conducted to investigate the effects of strength non-homogeneity, embedment depths, and the spudcan’s size on the elastic stiffness. On these bases, an expression is provided such that the practicing engineers can conveniently factor the installation effects into the estimation of elastic stiffness coefficients of spudcans.

Optimisation using the finite element method of a filter-based microfluidic SERS sensor for detection of multiple pesticides in strawberry - Sara Asgari; Guangfu Wu; S. Ali Aghvami; Yi Zhang; Mengshi Lin (Food Additives & Contaminants: Part A, 2021)

Mesenchymal Stromal Cell-Derived Extracellular Vesicles in the Treatment of Diabetic Foot Ulcers: Application and Challenges - Tao An; Yi Chen; Yingchun Tu; Ping Lin (Stem Cell Reviews and Reports, 2021)

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

Evidence-based Customized Ankle-Foot Orthosis with Energy Storage - Chih-Chun Lin; Chien-Hsien Yeh; Yi-Chun Tsai; Li-Chieh Kuo; Hsiu-Yun Hsu; Ping-Han Chuang; Kai Chang; Fong-Chin Su (Journal of Medical and Biological Engineering, 2021)

Microbiological profiles and antimicrobial resistance patterns of pediatric bloodstream pathogens in China, 2016–2018 - Yue Qiu; Junwen Yang; Yiping Chen; Jinhong Yang; Qingxiong Zhu; Chunhui Zhu; Shuangjie Li; Jing Liu; Chaomin Wan; Yu Zhu; Minxia Chen; Yi Xu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Dissolution of PbS, CuS, and ZnS in oxic waters: effects of adsorbed natural organic matter - Yi-Pin Lin; I-Chia Li; Ping-I Chou (Environmental Science and Pollution Research, 2021)

Efficiency assessment of coal energy and non-coal energy under bound dynamic DDF DEA - Ying Li; Tai-Yu Lin; Yung-ho Chiu; Hongyi Cen; Yi-Nuo Lin (Environmental Science and Pollution Research, 2021)

Crenobacter intestini sp. nov., Isolated from the Intestinal Tract of Konosirus punctatus - Song-Biao Shi; Jia-Fa Wu; Li-Fang Yang; Ming-Guo Jiang; Cai-Mi Gao; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Correction to: Bio-electrospraying is a safe technology for delivering human adipose-derived stem cells - Chuan Ye; Zhixu He; Yunfeng Lin; Yi Zhang; Jin Tang; Bo Sun; Minxian Ma; Jielin Liu; Long Yang; Houxiang Ren; Baoping Zhao (Biotechnology Letters, 2021)

Assimilation of Radar and Cloud-to-Ground Lightning Data Using WRF-3DVar Combined with the Physical Initialization Method—A Case Study of a Mesoscale Convective System - Ruhui Gan; Yi Yang; Qian Xie; Erliang Lin; Ying Wang; Peng Liu (Journal of Meteorological Research, 2021)

Microbiome Reengineering by Heat Selection for Rapid Biodegradation of Trichloroethylene with Minimal Vinyl Chloride Formation - Ai-Lin Chan; Chien-Yun Tseng; Tzu-Wen Chen; Yi-Hsuan Lo; Shu-Chi Chang (Water, Air, & Soil Pollution, 2021)

Biomimetic Au nanodot synthesis using Escherichia coli secretion and interaction with α-ketoglutaric acid - Xiaoxiao Xie; Xiaoli Yang; Yi Chang; Xiangli Ru; Xiaoming Ma; Lin Yang (Science China Life Sciences, 2021)

Clinacanthus nutans Mitigates Neuronal Death and Reduces Ischemic Brain Injury: Role of NF-κB-driven IL-1β Transcription - Mei-Han Kao; Jui-Sheng Wu; Wai-Mui Cheung; Jin-Jer Chen; Grace Y. Sun; Wei-Yi Ong; Deron R. Herr; Teng-Nan Lin (NeuroMolecular Medicine, 2021)

Shallow gas hydrates off southwest Taiwan and their mechanisms - Yin-Sheng Huang; Shu-Kun Hsu; Chih-Chieh Su; Andrew Tien-Shun Lin; Pai-Sen Yu; Nathalie Babonneau; Gueorgui Ratzov; Serge Lallemand; Pi-Chuen Huang; Shiao-Shan Lin; Jing-Yi Lin; Kuo-Yen Wei; et al. (Marine Geophysical Research, 2021)
We have collected two shallow gas hydrate samples at two sites having different geological settings off southwest Taiwan during the cruise MD214 in 2018. The first core site, MD18-3542, is on the South Yuan-An East Ridge at ~ 1200 m water deep, where a structural unconformity covered by fine-silt sediments appears at ~ 5.5 m below the seafloor. The second core site, MD18-3543, is close to the Good-Weather Ridge at ~ 1100 m water deep, where a gas-related pockmark structure and authigenic carbonates are present at shallow strata with fine-silt sediments near the seafloor. Sediment properties of core MD18-3542 are distinctively different above and below the layer corresponding to the unconformity. Both cores show obvious gaps or voids in the lower core halves. The core features could be linked to the dissociated methane upward migrating from deep strata. Core site settings with upwelling methane would favor the formation of shallow gas hydrates. At site MD18-3542, the shallow hydrate could be formed due to high concentration methane kept beneath the unconformity covered by fine-silt sediments. At site MD18-3543, the shallow hydrate could be formed due to an extremely high flux of upwelling methane trapped either beneath the authigenic carbonates or fine-silt sediments.

Correction to: IL-17A Induces MIP-1α Expression in Primary Astrocytes Via Src/MAPK/PI3K/NF-kB Pathways: Implications for Multiple Sclerosis - Hongwei Yi; Ying Bai; Xinjian Zhu; Lin Lin; Lei Zhao; Xiaodong Wu; Shilpa Buch; Longxin Wang; Jie Chao; Honghong Yao (Journal of Neuroimmune Pharmacology, 2021)

RING-finger protein 5 promotes hepatocellular carcinoma progression and predicts poor prognosis - Yi Zhang; Jie Li; Huayang Chen; Changmao Zhang; Song You; Yue Zhao; Xiaoning Lin; Yaqi Yu; Fei Fang; Ting Fang; Xiaomin Wang (Human Cell, 2021)

Integrated and segregated frequency architecture of the human brain network - Junji Ma; Ying Lin; Chuanlin Hu; Jinbo Zhang; Yangyang Yi; Zhengjia Dai (Brain Structure and Function, 2021)

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

Continental shelf morphology controlled by bottom currents, mud diapirism, and submarine slumping to the east of the Gaoping Canyon, off SW Taiwan - Yi-Ching Yeh; Chung-Lin Tsai; Shu-Kun Hsu; Hsiao-Shan Lin; Kuan-Ting Chen; Yen-Yu Cho; Chin-Wei Liang (Geo-Marine Letters, 2021)

Classification of Northeast China Cold Vortex Activity Paths in Early Summer Based on K-means Clustering and Their Climate Impact - Yihe Fang; Haishan Chen; Yi Lin; Chunyu Zhao; Yitong Lin; Fang Zhou (Advances in Atmospheric Sciences, 2021)

Experimental Investigation of CS2 Extraction to Enhance the Permeability of Coal - Zhen Zhang; Gaofeng Liu; Yunxing Cao; Jia Lin; Yi Jin; Baoan Xian; Runsheng Lv; Zhou Zhang (Transport in Porous Media, 2021)

Small RNA Sequencing Analysis of Germinating Single-bud Seedcane Sett in Sugarcane - Kai-Chao Wu; Lin Xu; Zhi-Nian Deng; Tian Pang; Rong-Hua Zhang; Yi-Jie Li; Xiao-Yan Liu; Cheng-Feng Huang; Wen-Xian Qin; Jian-Feng Wei; Li-Ping Wei; Yang-Rui Li; et al. (Sugar Tech, 2021)

Methylation of RILP in lung cancer promotes tumor cell proliferation and invasion - Jianbo Lin; Yi Zhuo; Yinhe Yin; Linbin Qiu; Xu Li; Fancai Lai (Molecular and Cellular Biochemistry, 2021)

Assisted selection of eating quality progeny of indica (O. sativa L. ssp. indica) and japonica (O. sativa L. ssp. japonica) hybrids using rice starch properties - Ting Mao; Zhan Zhang; Shan Jun Ni; Yi Zhou Zhao; Xin Li; Li Li Zhang; Yan Liu; Cheng Shun Zhong; He Huang; Shao Lin Wang; Xu Li (Genetic Resources and Crop Evolution, 2021)

Genotyping-by-sequencing to determine the genetic structure of a Tibetan medicinal plant Swertia mussotii Franch. - Yan Qiao; Fengxian Guo; Naxin Huo; Lin Zhan; Jiaqing Sun; Xixi Zuo; Zeguang Guo; Yong Q. Gu; Yi Wang; Yue Liu (Genetic Resources and Crop Evolution, 2021)

Direct Calculation Method for the Analysis of Non-linear Behavior of Ground-Support Interaction of a Circular Tunnel Using Convergence Confinement Approach - Yu-Lin Lee; Wen-Kuei Hsu; Chi-Min Lee; Yi-Xian Xin; Bo-Yu Zhou (Geotechnical and Geological Engineering, 2021)

Effects of high levels of nitrogen and phosphorus on perennial ryegrass (Lolium perenne L.) and its potential in bioremediation of highly eutrophic water - Hai-Shun Xu; Lin Zhu; Yi Mei (Environmental Science and Pollution Research, 2021)

Paracoccus lichenicola sp. nov., Isolated from Lichen - Lei Lang; De-Feng An; Long-Qian Jiang; Gui-Ding Li; Li-Song Wang; Xin-Yu Wang; Qin-Yuan Li; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Associations of Serum Selenium Levels in the First Trimester of Pregnancy with the Risk of Gestational Diabetes Mellitus and Preterm Birth: a Preliminary Cohort Study - Peng Ju Liu; Aimin Yao; Liangkun Ma; Xiao Yan Chen; Song Lin Yu; Yanping Liu; Yi Xuan Hou (Biological Trace Element Research, 2021)

Rapid assessment of landslide risk level based on deep learning - Fei Tan; Jin Yu; Yu-Yong Jiao; Dawei Lin; Jiahe Lv; Yi Cheng (Arabian Journal of Geosciences, 2021)

CAS-ESM2.0 Model Datasets for the CMIP6 Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) - Jiangbo Jin; He Zhang; Xiao Dong; Hailong Liu; Minghua Zhang; Xin Gao; Juanxiong He; Zhaoyang Chai; Qingcun Zeng; Guangqing Zhou; Zhaohui Lin; Yi Yu; et al. (Advances in Atmospheric Sciences, 2021)
The second version of the Chinese Academy of Sciences Earth System Model (CAS-ESM2.0) is participating in the Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) experiments in phase 6 of the Coupled Model Intercomparison Project (CMIP6). The purpose of FAFMIP is to understand and reduce the uncertainty of ocean climate changes in response to increased CO 2 forcing in atmosphere-ocean general circulation models (AOGCMs), including the simulations of ocean heat content (OHC) change, ocean circulation change, and sea level rise due to thermal expansion. FAFMIP experiments (including faf-heat, faf-stress, faf-water, faf-all, faf-passiveheat, faf-heat-NA50pct and faf-heat-NA0ct) have been conducted. All of the experiments were integrated over a 70-year period and the corresponding data have been uploaded to the Earth System Grid Federation data server for CMIP6 users to download. This paper describes the experimental design and model datasets and evaluates the preliminary results of CAS-ESM2.0 simulations of ocean climate changes in the FAFMIP experiments. The simulations of the changes in global ocean temperature, Atlantic Meridional Overturning Circulation (AMOC), OHC., and dynamic sea level (DSL), are all reasonably reproduced.

Translocation and distribution of mercury in biomasses from subtropical forest ecosystems: evidence from stable mercury isotopes - Yi Liu; Che-Jen Lin; Wei Yuan; Zhiyun Lu; Xinbin Feng (Acta Geochimica, 2021)

Community structure of bacterioplankton and its relationship with environmental factors in the upper reaches of the Heihe River in Qinghai Plateau - Zhang Qian‐Qian; Jian Sheng‐Long; Li Ke‐Mao; Wu Zhen‐Bing; Guan Hong‐Tao; Hao Jin‐Wen; Wang Shu‐Yi; Lin Yao‐Yao; Wang Guo‐Jie; Li Ai‐Hua (Environmental Microbiology, 2021)
Summary Planktonic microorganisms play a key role in the biogeochemical processes of the aquatic system, and they may be affected by many factors. High‐throughput sequencing technology was used in this study to investigate and study the bacterioplankton community of water bodies in the upper reaches of the Heihe River Basin in Qinghai Plateau. Results showed that Proteobacteria, Firmicutes, Bacteroidetes and Actinobacteria are the predominant phyla in this river section, while the main genera are Thiomonas , Acidibacillus , Acidocella , Rhodanobacter , Acidithiobacter and Gallionella , which are autochthonous in the acid‐mine drainage. Additionally, total nitrogen, total phosphorus, permanganate index and pH are significantly correlated with the bacterioplankton abundance and are the main limiting factors for the spatial distribution of the bacterioplankton. PICRUSt inferred that the mainstream microbial assemblages had a higher abundance of KOs belong to metabolism of terpenoids and polyketides, while the tributary had higher abundance of KOs belong to the immune system. The relationship between bacterioplankton community composition and environmental factors in the Heihe River basin was discussed for the first time in this study, which provides a theoretical basis for the healthy, orderly development of the water environment in the Heihe River Basin.

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Triterpenoids from the fresh pericarps of Juglans hopeiensis - Yi Lin; Xiaogang Peng; Juan Chen; Jia Zhou; Hanli Ruan (Natural Product Research, 2021)

Further data on the levels of emerging Fusarium mycotoxins in cereals collected from Tianjin, China - Xiaohui Lin; Qian Zhang; Yi Zhang; Jianping Li; Mingyue Zhang; Xiao Hu; Fengqin Li (Food Additives & Contaminants Part B-Surveillance, 2021)

Verification of the biomass transfer hypothesis under moderate grazing across the Tibetan plateau: a meta-analysis - Jian Sun; Tianyu Zhan; Miao Liu; Zhenchao Zhang; Yi Wang; Shiliang Liu; Gao-lin Wu; Guohua Liu; Atsushi Tsunekawa (Plant and Soil, 2021)

Astrocyte-Derived Lactate Modulates the Passive Coping Response to Behavioral Challenge in Male Mice - Ya-Nan Yin; Jian Hu; Yi-Li Wei; Ze-Lin Li; Zhou-Cai Luo; Rui-Qi Wang; Ke-Xin Yang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications - Wei-Yi Ong; Mei-Lin Go; De-Yun Wang; Irwin Kee-Mun Cheah; Barry Halliwell (Molecular Neurobiology, 2021)
The SARS-CoV-2 virus that is the cause of coronavirus disease 2019 (COVID-19) affects not only peripheral organs such as the lungs and blood vessels, but also the central nervous system (CNS)—as seen by effects on smell, taste, seizures, stroke, neuropathological findings and possibly, loss of control of respiration resulting in silent hypoxemia. COVID-19 induces an inflammatory response and, in severe cases, a cytokine storm that can damage the CNS. Antimalarials have unique properties that distinguish them from other anti-inflammatory drugs. (A) They are very lipophilic, which enhances their ability to cross the blood-brain barrier (BBB). Hence, they have the potential to act not only in the periphery but also in the CNS, and could be a useful addition to our limited armamentarium against the SARS-CoV-2 virus. (B) They are non-selective inhibitors of phospholipase A 2 isoforms, including cytosolic phospholipase A 2 (cPLA 2 ). The latter is not only activated by cytokines but itself generates arachidonic acid, which is metabolized by cyclooxygenase (COX) to pro-inflammatory eicosanoids. Free radicals are produced in this process, which can lead to oxidative damage to the CNS. There are at least 4 ways that antimalarials could be useful in combating COVID-19. (1) They inhibit PLA 2. (2) They are basic molecules capable of affecting the pH of lysosomes and inhibiting the activity of lysosomal enzymes. (3) They may affect the expression and Fe 2+ /H + symporter activity of iron transporters such as divalent metal transporter 1 (DMT1), hence reducing iron accumulation in tissues and iron-catalysed free radical formation. (4) They could affect viral replication. The latter may be related to their effect on inhibition of PLA 2 isoforms. Inhibition of cPLA 2 impairs an early step of coronavirus replication in cell culture. In addition, a secretory PLA 2 (sPLA 2 ) isoform, PLA2G2D, has been shown to be essential for the lethality of SARS-CoV in mice. It is important to take note of what ongoing clinical trials on chloroquine and hydroxychloroquine can eventually tell us about the use of antimalarials and other anti-inflammatory agents, not only for the treatment of COVID-19, but also for neurovascular disorders such as stroke and vascular dementia.

Improved control of Frankliniella occidentalis on greenhouse pepper through the integration of Orius sauteri and neonicotinoid insecticides - Qing-cai Lin; Hao Chen; Dirk Babendreier; Jin-ping Zhang; Feng Zhang; Xiao-yan Dai; Zuo-wen Sun; Zhao-peng Shi; Xiao-lin Dong; Guang-an Wu; Yi Yu; Li Zheng; et al. (Journal of Pest Science, 2021)

Risk of mental illness after the diagnosis of occupational injury or disease: a retrospective cohort study - Ming-Hung Lin; Ya-Lun Yang; Fung-Chung Sung; Chiu-Shong Liu; Chi-Hsuan Lung; Jong-Yi Wang (International Archives of Occupational and Environmental Health, 2021)

Pullout Behavior of Sensor-Enabled Geobelts in Weathered Rock Material–Granulated Rubber Mixtures - Yi-lin Wang; Xin-zhuang Cui; Jin Li; Lei Wang; Jun Li; Jun-wei Su (Geotechnical and Geological Engineering, 2021)

How does population structure affect pollutant discharge in China? Evidence from an improved STIRPAT model - Li Cao; Lin Li; Yi Wu (Environmental Science and Pollution Research, 2021)

Low ambient temperature increases hospital re-admissions for systemic lupus erythematosus in humid subtropical region: a time series study - Qian Wu; Zhiwei Xu; Yi-Lin Dan; Peng Wang; Yan-Mei Mao; Chan-Na Zhao; Yan-Feng Zou; Dong-Qing Ye; Wenbiao Hu; Hai-Feng Pan (Environmental Science and Pollution Research, 2021)

Land use and land cover change within the Koshi River Basin of the central Himalayas since 1990 - Fang-di Xie; Xue Wu; Lin-shan Liu; Yi-li Zhang; Basanta Paudel (Journal of Mountain Science, 2021)

Improving the observation and prediction capabilities for Arctic marine environment: from the perspective of Arctic Shipping - Hui Wang; Qizhen Sun; Lin Zhang; Xi Liang; Qinghua Yang; Na Liu; Chunhua Li; Qingsheng Liu; Bingrui Li; Qian Feng; Xiao Cheng; Yi Yu (Acta Oceanologica Sinica, 2021)

Production of functional human nerve growth factor from the submandibular glands of mice using a CRISPR/Cas9 genome editing system - Yi Gu; Hui Cao; Fei Li; Jianli Yu; Rui Nian; Dongxiao Feng; Jingtao Lin; Haipeng Song; Wenshuai Liu (World Journal of Microbiology and Biotechnology, 2020)

Concurrent increases in post-pacing action potential duration and contractility predict occurrence of ventricular arrhythmia - Chih-Min Liu; Feng-Zhi Lin; Yao-Chang Chen; Yung-Kuo Lin; Yen-Yu Lu; Cheng-I Wu; Satoshi Higa; Shih-Ann Chen; Yi-Jen Chen (Pflügers Archiv - European Journal of Physiology, 2020)

Melatonin ameliorates spatial memory and motor deficits via preserving the integrity of cortical and hippocampal dendritic spine morphology in mice with neurotrauma - Xiao-Jing Lin; Ruoxu Liu; Chenyi Li; Xueqing Yi; Bo Fu; M. J. Walker; Xiao-Ming Xu; Gang Sun; Cheng-Hsien Lin (Inflammopharmacology, 2020)

Evaluations of the serological test in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak - Dachuan Lin; Lei Liu; Mingxia Zhang; Yunlong Hu; Qianting Yang; Jiubiao Guo; Youchao Dai; Yuzhong Xu; Yi Cai; Xinchun Chen; Kaisong Huang; Zheng Zhang (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Load Distribution at the Patellofemoral Joint During Walking - Lucas T. Thomeer; Yi-Chung Lin; Marcus G. Pandy (Annals of Biomedical Engineering, 2020)

Structural insights into Arabidopsis ethylene response factor 96 with an extended N-terminal binding to GCC box - Chun-Yen Chen; Pei-Hsuan Lin; Kun-Hung Chen; Yi-Sheng Cheng (Plant Molecular Biology, 2020)
The phytohormone ethylene is widely involved in many developmental processes and is a crucial regulator of defense responses against biotic and abiotic stresses in plants. Ethylene-responsive element binding protein, a member of the APETALA2/ethylene response factor (AP2/ERF) superfamily, is a transcription factor that regulates stress-responsive genes by recognizing a specific cis -acting element of target DNA. A previous study showed only the NMR structure of the AP2/ERF domain of AtERF100 in complex with a GCC box DNA motif. In this report, we determined the crystal structure of AtERF96 in complex with a GCC box at atomic resolution. We analyzed the binding residues of the conserved AP2/ERF domain in the DNA recognition sequence. In addition to the AP2/ERF domain, an N-terminal α-helix of AtERF96 participates in DNA interaction in the flanking region. We also demonstrated the structure of AtERF96 EDLL motif, a unique conserved motif in the group IX of AP2/ERF family, might involve in the transactivation of defense-related genes. Our study establishes the structural basis of the AtERF96 transcription factor in complex with the GCC box, as well as the DNA binding mechanisms of the N-terminal α-helix and AP2/ERF domain.

Correction to: Application of linked and unlinked co‑transformation to generate triple stack, marker‑free, transgenic white clover (Trifolium repens L.) - Rafael Narancio; Yong-Lin Ding; Yi-Han Lin; Sareena Sahab; Stephen Panter; Matthew Hayes; Ulrik John; Heather Anderson; John Mason; German Spangenberg (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

The determination of a novel inducible WY172 promoter derived from Oidium heveae HO-73 - Jinyao Yin; Yi Wang; Li Zhu; Chen Wang; Jiyuan Wang; Wenbo Liu; Chunhua Lin; Xiao Li; Weiguo Miao (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

One-pot synthesis of substituted pyrrole–imidazole derivatives with anticancer activity - Ming Zhang; Yong Ding; Hong-Xia Qin; Zhi-Gang Xu; Hai-Tao Lan; Dong-Lin Yang; Cheng Yi (Molecular Diversity, 2020)

Grazing by microzooplankton and copepods on the microbial food web in spring in the southern Yellow Sea, China - Yuan Zhao; Yi Dong; Haibo Li; Shiquan Lin; Lingfeng Huang; Tian Xiao; Gerald Gregori; Li Zhao; Wuchang Zhang (Marine Life Science & Technology, 2020)
Assessment of microzooplankton and copepods grazing pressure on picoplankton is a key requirement for resolving the microbial food web efficiency. Although microzooplankton grazing on picoplankton has been extensively studied, the impact of microzooplankton on different groups of picoplankton, i.e., heterotrophic bacteria, Synechococcus and picoeukaryotes have rarely been compared. Furthermore, in the very few existing studies there is no consistent evidence of an enhancing or restraining effect of copepods on picoplankton. More studies are needed to improve our understanding of the influence of microzooplankton and copepod on picoplankton. Dilution incubations and copepod addition incubations were performed during a cruise to the southern Yellow Sea on May 16–29, 2007. The bulk grazing of microzooplankton and the calanoid copepod Calanus sinicus on phytoplankton, flagellates and picoplankton was estimated. Stations were divided into either eutrophic or oligotrophic according to the nutrient and biological parameters. Picoplankton comprised a large part of the diet of microzooplankton in the central oligotrophic area, while phytoplankton was the main food of microzooplankton in the coastal eutrophic area. In the central oligotrophic area, microzooplankton preferred grazing on Synechococcus . After copepod addition, ciliate abundance decreased while Synechococcus abundance increased (382%, 64% and 64% at three experimental stations, respectively), indicating strong grazing pressure of microzooplankton on Synechococcus . Our results suggest that Synechococcus might be an essential carbon source the planktonic food web in the oligotrophic waters of southern Yellow Sea.

Effects of intercropping accumulator plants and applying their straw on the growth and cadmium accumulation of Brassica chinensis L. - Yi Tang; Liming Wang; Yongdong Xie; Xuena Yu; LiJin Lin; Huanxiu Li; Ming’an Liao; Zhihui Wang; Guochao Sun; Dong Liang; Hui Xia; Xun Wang; et al. (Environmental Science and Pollution Research, 2020)

Liver Function of Male Rats Exposed to Manganese at Different Time Points - Xiaonian Zhu; Lin Yang; Yonghua He; Yi Sun; Wenxiang Shi; Chaoyan Ou (Biological Trace Element Research, 2020)

Correction to: Complete genome sequences of two novel dicistroviruses detected in yellow crazy ants (Anoplolepis gracilipes) - Chih-Chi Lee; Chun-Yi Lin; Hung-Wei Hsu; Chin-Cheng Scotty Yang (Archives of Virology, 2020)

Complete genome sequences of two novel dicistroviruses detected in yellow crazy ants (Anoplolepis gracilipes) - Chih-Chi Lee; Chun-Yi Lin; Hung-Wei Hsu; Chin-Cheng Scotty Yang (Archives of Virology, 2020)

Nitrogen‐induced acidification, not N‐nutrient, dominates suppressive N effects on arbuscular mycorrhizal fungi - Shang Pan; Yang Wang; Yunpeng Qiu; Dima Chen; Lin Zhang; Chenglong Ye; Hui Guo; Weixing Zhu; Aiqun Chen; Guohua Xu; Yi Zhang; Yongfei Bai; et al. (Global Change Biology, 2020)
Arbuscular mycorrhizal fungi (AMF) form symbiosis with most terrestrial plant roots, obtaining photosynthates in return for mineral nutrients. Ecological theories based on the economics of trading partnership predict that nutrient enrichment would suppress AMF. Experimental results from nitrogen (N) and phosphorus (P) additions, however, were highly variable, and the underlying mechanisms remain unclear. Here we show distinct AMF responses to soil N:P stoichiometry manipulations via gradients of long‐term N and P additions in a Mongolian steppe. A complementary experiment with an acid addition gradient was designed to help tease apart the effect of N‐induced acidification from N nutrient. AMF root colonization and extraradical fungal biomass progressively decreased along the P gradient under two distinct host plant species, suggesting a carbon (C)‐P tradeoff. In contrast, low to moderate N inputs increased both AMF parameters, corresponding to the increasing N:P ratio. Yet, high N inputs reduced AMF colonization and biomass, and the magnitudes of N‐led inhibition were similar to those under acid additions that induced comparable changes in soil pH. Structural equation modeling further showed that while soil N:P stoichiometry primarily controlled the effect of P addition on AMF, N‐induced soil acidity overtook the N:P stoichiometry under high N inputs and dominated the effects of reactive N on AMF. In addition, AMF community composition in roots was more dependent on host plants and unresponsive to changes in soil nutrients. We further proposed a comprehensive framework that integrates biological and geochemical effects of reactive N and P inputs on AMF. Together, these results indicate that while the C‐P tradeoff controls P suppression of AMF, N‐induced acidification dominates the N inhibition. Our findings suggest that incorporation of geochemical impacts of N and P inputs would facilitate modeling efforts to project mycorrhizal impact on plant interactions and soil C balance under future nutrient enrichment scenarios.

Intrusion of Kuroshio Helps to Diminish Coastal Hypoxia in the Coast of Northern South China Sea - Hon-Kit Lui; Chen-Tung Arthur Chen; Wei-Ping Hou; Jian-Ming Liau; Wen-Chen Chou; You-Lin Wang; Chau-Ron Wu; Jay Lee; Yi-Chia Hsin; Yan-Yu Choi (Frontiers in Marine Science, 2020)

Two new compounds from the heartwood of Dalbergia melanoxylon - Shuai Lin; Rong-Hua Liu; Guang-Qiang Ma; Dan-Yi Mei; Feng Shao; Lan-Ying Chen (Natural Product Research, 2020)

The relationship between solar-induced fluorescence and gross primary productivity under different growth conditions: global analysis using satellite and biogeochemical model data - Haoran Zhou; Dun Wu; Yi Lin (International Journal of Remote Sensing, 2020)

Elucidation of Gut Microbiota in Mud Crab Scylla paramamosain Challenged to WSSV and Aeromonas hydrophila - Shanmeng Lin; Tongtong Kong; Xin Ren; Shengkang Li; Yi Gong (Marine Biotechnology, 2020)

Mild acidity likely accelerates the physiological matriptase autoactivation process: a comparative study between spontaneous and acid-induced matriptase zymogen activation - Bailing Jia; Hamishi A. Thompson; Robert B. Barndt; Yi-Lin Chiu; Mon-Juan Lee; See-Chi Lee; Jehng-Kang Wang; Hung-Jen Tang; Chen-Yong Lin; Michael D. Johnson (Human Cell, 2020)

Feasibility of using bed filters packed with rice-straw-based activated carbon and selected biomass waste for the control of frying fume exhaust - Yen-Chi Chen; Xuan-En Yang; Kun-Yi Lin; Wei-Wen Huang; Chi-Chi Lin; Kuo-Pin Yu (Environmental Science and Pollution Research, 2020)

Chemical composition, antioxidant, antimicrobial and anticancer activities of the essential oil from the rhizomes of Zingiber striolatum Diels - Minyi Tian; Tingting Liu; Xianghuan Wu; Yi Hong; Xiongli Liu; Bing Lin; Ying Zhou (Natural Product Research, 2020)

Lactobacillus plantarum PS128 Ameliorated Visceral Hypersensitivity in Rats Through the Gut–Brain Axis - Yen-Wenn Liu; Yen-Po Wang; Hsu-Fang Yen; Pei-Yi Liu; Wen-Jian Tzeng; Chia-Fen Tsai; Han-Chieh Lin; Fa-Yauh Lee; One-Jang Jeng; Ching-Liang Lu; Ying-Chieh Tsai (Probiotics and Antimicrobial Proteins, 2020)

Application of linked and unlinked co-transformation to generate triple stack, marker-free, transgenic white clover (Trifolium repens L.) - Rafael Narancio; Yong-Lin Ding; Yi-Han Lin; Sareena Sahab; Stephen Panter; Matthew Hayes; Ulrik John; Heather Anderson; John Mason; German Spangenberg (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Upregulation of miR-133a-3p in the Sciatic Nerve Contributes to Neuropathic Pain Development - Lin-Li Chang; Hung-Chen Wang; Kuang-Yi Tseng; Miao-Pei Su; Jaw-Yuan Wang; Yi-Ta Chuang; Yi-Hsuan Wang; Kuang-I Cheng (Molecular Neurobiology, 2020)

Correction to: Telomerase reconstitution contributes to resetting of circadian rhythm in fibroblasts - Yi Qu; Meng Mao; Xihong Li; Yanyou Liu; Jianmin Ding; Zhou Jiang; Chaomin Wan; Lin Zhang; Zhengrong Wang; Dezhi Mu (Molecular and Cellular Biochemistry, 2020)

Effect of Calcium-Based Catalysts on Pyrolysis Liquid Products from Municipal Sludge - Wei Luo; Yi-Feng Su; Qing Hu; Huai-Lin Yin; Shuo Wang; Li-Jiao Ao; Xiao-Xi Wen; Sheng-Xiong Huang; Nan Zhou; Wei Zhang; Zhi Zhou (BioEnergy Research, 2020)

Potential probiotic of Lactobacillus strains isolated from the intestinal tracts of pigs and feces of dogs with antibacterial activity against multidrug-resistant pathogenic bacteria - Chuen-Fu Lin; Meng-Yi Lin; Chao-Nan Lin; Ming-Tang Chiou; Jia-Wen Chen; Kai-Chieh Yang; Ming-Cheng Wu (Archives of Microbiology, 2020)

(–)-β-Homoarginine anhydride, a new antioxidant and tyrosinase inhibitor, and further active components from Trichosanthes truncata - I-Ting Weng; Yen-An Lin; Guan-Yu Chen; Hsiu-Mei Chiang; Yi-Jung Liu; Chao-Jung Chen; Yu-Hsuan Lan; Chia-Lin Lee (Natural Product Research, 2020)

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study - Shao-rui Hao; Ren Yan; Shan-yan Zhang; Jiang-shan Lian; Huan Cai; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

The Health Promoting Mindfulness or Qigong Educational Programs for Beneficial Lifestyle Changes of Cancer Survivors - Tse-Chou Cheng; Yi-Hua Lee; Chun-Lin Mar; Wen-Tsung Huang; Yuan-Ping Chang (Journal of Cancer Education, 2020)

Nakamurella albus sp. nov.: A Novel Actinobacterium Isolated from a Lichen Sample - Long-Qian Jiang; De-Feng An; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Lei Lang; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2020)

Reconnaissance and learning after the February 6, 2018, earthquake in Hualien, Taiwan - Jui-Liang Lin; Chun-Hsiang Kuo; Yu-Wen Chang; Shu-Hsien Chao; Yi-An Li; Wen-Cheng Shen; Chung-Han Yu; Cho-Yen Yang; Fan-Ru Lin; Hsiao-Hui Hung; Chun-Chung Chen; Chin-Kuo Su; et al. (Bulletin of Earthquake Engineering, 2020)

Experimental investigation for dynamic instability of coal-rock masses in horizontal section mining of steeply inclined coal seams - Zheng-yi Wang; Lin-ming Dou; Jiang He; An-ye Cao; Xiong-wei Li; Peng-bo Li; Chang-sheng Wu (Arabian Journal of Geosciences, 2020)

General review of optical polarization remote sensing - Lei Yan; Yanfei Li; V. Chandrasekar; Hugh Mortimer; Jouni Peltoniemi; Yi Lin (International Journal of Remote Sensing, 2020)

Relationship Between Seismic Moment and Source Duration for Seismogenic Earthquakes in Taiwan: Implications for the Product of Static Stress Drop and the Cube of Rupture Velocity - Ruey-Der Hwang; Cheng-Ying Ho; Tzu-Wei Lin; Wen-Yen Chang; Yi-Ling Huang; Cai-Yi Lin; Chiung-Yao Lin (Pure and Applied Geophysics, 2020)

Supportive role of the Na+ transporter CmHKT1;1 from Cucumis melo in transgenic Arabidopsis salt tolerance through improved K+/Na+ balance - Li-Wei Gao; Sen-Lin Yang; Shi-Wei Wei; Dan-Feng Huang; Yi-Dong Zhang (Plant Molecular Biology, 2020)

Metabolomics analysis of nitrogen-containing metabolites between two Dendrobium plants - Cheng Song; Chunyan Jiao; Qing Jin; Cunwu Chen; Yongping Cai; Yi Lin (Physiology and Molecular Biology of Plants, 2020)

Astrocytic GABAB Receptors in Mouse Hippocampus Control Responses to Behavioral Challenges through Astrocytic BDNF - Ji-Hong Liu; Ze-Lin Li; Yi-Si Liu; Huai-De Chu; Neng-Yuan Hu; Ding-Yu Wu; Lang Huang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2020)

Methylation of Phospholipase A2 Group VII Gene Is Associated with Brain Arteriovenous Malformations in Han Chinese Populations - Yuchun Liu; Xizheng Wu; Sheng Nie; Shengjun Zhou; Shuyuan Xiao; Xiang Gao; Zhiqing Lin; Jie Sun; Yi Huang (Journal of Molecular Neuroscience, 2020)

Ecological risk evaluation and source apportionment of heavy metals in park playgrounds: a case study in Xi’an, Shaanxi Province, a northwest city of China - Bin Guo; Yi Su; Lin Pei; Xiaofeng Wang; Bo Zhang; Dingming Zhang; Xiaoxia Wang (Environmental Science and Pollution Research, 2020)

Toxicity assessment of electrochemical advanced oxidation process-treated groundwater from a gas station with petrochemical contamination - How-Ran Chao; Danielle E. Que; Alisha C. Aquino; Yan-You Gou; Lemmuel L. Tayo; Yi-Hsien Lin; Ming-Hsien Tsai; Fu-Lin Hsu; I-Cheng Lu; Sheng-Lun Lin; Natwat Srikhao; Cherng-Gueih Shy; et al. (Environmental Monitoring and Assessment, 2020)

Halorussus halophilus sp. nov., A Novel Halophilic Archaeon Isolated from a Marine Solar Saltern - Yi Ding; Dong Han; Heng-Lin Cui (Current Microbiology, 2020)

A novel putative betapartitivirus isolated from the plant-pathogenic fungus Rhizoctonia solani - Yi Chen; Jia En Su; Xi Yun Qin; Zhi Yong Fan; Xiao Hai Zhang; Qing Yu; Zhen Yuan Xia; Cong Ming Zou; Gao Kun Zhao; Zhong Long Lin (Archives of Virology, 2020)

Description of Gemmobacter aestuarii sp. nov., isolated from estuarine surface water and reclassification of Cereibacter changlensis as Gemmobacter changlensis Chen et al. 2013 - Asif Hameed; Mariyam Shahina; Shih-Yao Lin; Wen-Ming Chen; Yi-Han Hsu; Wei-An Lai; Chiu-Chung Young (Archives of Microbiology, 2020)

Description of Azoarcus nasutitermitis sp. nov. and Azoarcus rhizosphaerae sp. nov., two nitrogen-fixing species isolated from termite nest and rhizosphere of Ficus religiosa - Shih-Yao Lin; Asif Hameed; Chia-Fang Tsai; Guan-Hua Huang; Yi-Han Hsu; Chiu-Chung Young (Antonie van Leeuwenhoek, 2020)

Contamination characteristics of heavy metals in particle size fractions from street dust from an industrial city, Central China - Ping Zhong; Jia-Quan Zhang; Da-Mao Xu; Qian Tian; Tian-Peng Hu; Xiang-Yi Gong; Chang-Lin Zhan; Shan Liu; Xin-Li Xing; Shi-Hua Qi (Air Quality, Atmosphere & Health, 2020)

The Fundamental and Functional Property Differences Between HPMC and PVP Co-Processed Herbal Particles Prepared by Fluid Bed Coating - Zhe Li; Fei Wu; YanLong Hong; Lan Shen; Xiao Lin; Yi Feng (AAPS PharmSciTech, 2020)

Population Genetic Analysis for Stock Enhancement of Silver Sea Bream (Rhabdosargus sarba) in Taiwan - Te-Hua Hsu; Chang-Wen Huang; Hung-Tai Lee; Yi-Hsuan Kuo; Kwang-Ming Liu; Cheng-Hui Lin; Hong-Yi Gong (Fishes, 2020)
Stock enhancement is a method for replenishing depleted wild finfish populations by supplementing them with hatchery-raised fish. In Taiwan, silver sea bream (Rhabdosargus sarba) is a predominant commercial species involved in stock enhancement projects. Although management agencies conduct stock enhancement projects, there are a lot of private releases without records. Stock enhancement is performed by the private aquaculture sector without accurate genetic records, potentially leading to unintended consequences for wild populations. We analyzed the genetics of 459 wild and 701 hatchery-reared specimens from nine batches produced by various hatcheries. Wild and hatchery-reared samples could be considered two separate clades by using a set of stable and informative microsatellite markers including type I (from gene introns and 3′UTR) and type II markers (randomly picked up from genome). Type I microsatellite markers could more sensitively reflect the loss of genetic diversity more than type II markers in the domestication process. All specimens were considered native by using mtDNA COI and microsatellites. The genetic composition of the wild population is relatively simple, and the estimated low contribution rate of the hatchery stock (1.3–10.9%; 6–50/459) indicated a weak but significant genetic effect of stock enhancement. Therefore, establishing standards for the stock enhancement of silver sea bream for more effective supplementation of wild populations is imperative.

Strength attenuation effects on rate-dependent law of stress development of frozen sand - Xiao-Liang Yao; Ji-Lin Qi; Ming-Yi Zhang; Fan Yu (European Journal of Environmental and Civil Engineering, 2020)

Biofertilizers with beneficial rhizobacteria improved plant growth and yield in chili (Capsicum annuum L.) - Jing-Yi Gou; Sheng-Zhou Suo; Kun-Zhong Shao; Qi Zhao; Dan Yao; Hui-Ping Li; Jin-Lin Zhang; Christopher Rensing (World Journal of Microbiology and Biotechnology, 2020)

Outflow sediment concentration forecasting by integrating machine learning approaches and time series analysis in reservoir desilting operation - Ming-Jui Chang; Gwo-Fong Lin; Fong-Zuo Lee; Yi-Cheng Wang; Peng-An Chen; Ming-Chang Wu; Jihn-Sung Lai (Stochastic Environmental Research and Risk Assessment, 2020)

Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway - Chung-I Yu; Cheng-I Cheng; Ya-Fei Kang; Po-Chih Chang; In-Pin Lin; Yu-His Kuo; An-Jie Jhou; Mei-Ying Lin; Chung-Yi Chen; Chien-Hsing Lee (Neurotoxicity Research, 2020)

Reversal of Social Recognition Deficit in Adult Mice with MECP2 Duplication via Normalization of MeCP2 in the Medial Prefrontal Cortex - Bin Yu; Bo Yuan; Jian-Kun Dai; Tian-lin Cheng; Sheng-Nan Xia; Ling-Jie He; Yi-Ting Yuan; Yue-Fang Zhang; Hua-Tai Xu; Fu-Qiang Xu; Zhi-Feng Liang; Zi-Long Qiu (Neuroscience Bulletin, 2020)

3D-QSAR, HQSAR, molecular docking, and new compound design study of 1,3,6-trisubstituted 1,4-diazepan-7-ones as human KLK7 inhibitors - Le Fu; Yi Chen; Chun-mei Xu; Tao Wu; Hong-mei Guo; Zhi-hua Lin; Rui Wang; Mao Shu (Medicinal Chemistry Research, 2020)

Ketamine Affects the Expression of ErbB4 in the Hippocampus and Prefrontal Cortex of Rats - Runfang Xie; Shijun Hong; Yi Ye; Xueyan Wang; Fan Chen; Lin Yang; Youyi Yan; Linchuan Liao (Journal of Molecular Neuroscience, 2020)

Cognitive Load of Exercise Influences Cognition and Neuroplasticity of Healthy Elderly: An Exploratory Investigation - Yi-Ping Chao; Changwei W. Wu; Li-Jung Lin; Cheng-Hung Lai; Hong-Yi Wu; Ai-Ling Hsu; Chiao-Nan Chen (Journal of Medical and Biological Engineering, 2020)
This study explored the effects of exercise with either high cognitive load or low cognitive load on cognitive performance and neuroplasticity in healthy elderly. Twenty-eight sedentary community-dwelling seniors participated in this study. Participants were assigned to one of three groups: the control group (C), low-cognitive load exercise group (LE), or high-cognitive load exercise group (HE). Individuals in both exercise groups engaged in moderate-intensity aerobic exercise for 4 months. Resting-state functional MRI and diffusion MRI were used to investigate the effects of intervention on functional and structural connectivity, respectively. Analysis of covariance with baseline, age and the education year as covariates was used to determine the effects of intervention. We found 4 months of exercise with high-cognitive load, but not exercise with low-cognitive load, improved the overall cognitive function of healthy elderly. Additionally, the HE group showed increased resting-state functional connectivity of superior frontal gyrus and anterior cingulate cortex and decreased functional connectivity of middle occipital gyrus and postcentral gyrus. The age-related alterations in local efficiency and betweenness were protected by exercise. Our findings might suggest that exercise with greater cognitive load likely results in greater training effects on cognition and brain connectivity than exercise requiring lower cognitive loads for healthy elderly.

Statistical Analysis on Heart Rate Variability for Graded Cardiopulmonary Groups with Different Exercise Intensities - Ching-Kun Chen; Shyan-Lung Lin; Cheng-Yi Huang; Tasi-Chu Wang; Ting-Yen Yao; Chieh-Liang Wu (Journal of Medical and Biological Engineering, 2020)

Acute physiological responses to combined blood flow restriction and low-level laser - Yi-Ching Chen; Yu-Han Su; Yen-Ting Lin; Chien-Chun Huang; Ing-Shiou Hwang (European Journal of Applied Physiology, 2020)

Fatigue-related modulation of low-frequency common drive to motor units - Ing-Shiou Hwang; Yen-Ting Lin; Chien-Chun Huang; Yi-Ching Chen (European Journal of Applied Physiology, 2020)

Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China - Cheng-yi Lin; Die Li; Jie-ming Lu; Zhe-bin Yu; Yao Zhu; Peng Shen; Meng-ling Tang; Ming-juan Jin; Hong-bo Lin; Li-ming Shui; Kun Chen; Jian-bing Wang (Environmental Science and Pollution Research, 2020)

Effects of Hyperbaric Oxygen Therapy on Acute Myocardial Infarction Following Carbon Monoxide Poisoning - Chien-Cheng Huang; Chung-Han Ho; Yi-Chen Chen; Chien-Chin Hsu; Hung-Jung Lin; Jhi-Joung Wang; Shih-Bin Su; How-Ran Guo (Cardiovascular Toxicology, 2020)