TLR8 in the Trigeminal Ganglion Contributes to the Maintenance of Trigeminal Neuropathic Pain in Mice - Lin-Xia Zhao; Ming Jiang; Xue-Qiang Bai; De-Li Cao; Xiao-Bo Wu; Jing Zhang; Jian-Shuang Guo; Tong-Tong Chen; Juan Wang; Hao Wu; Yong-Jing Gao; Zhi-Jun Zhang (Neuroscience Bulletin, 2021)
Trigeminal neuropathic pain (TNP) is a significant health problem but the involved mechanism has not been completely elucidated. Toll-like receptors (TLRs) have recently been demonstrated to be expressed in the dorsal root ganglion and involved in chronic pain. Here, we show that TLR8 was persistently increased in the trigeminal ganglion (TG) neurons in model of TNP induced by partial infraorbital nerve ligation (pIONL). In addition, deletion or knockdown of Tlr8 in the TG attenuated pIONL-induced mechanical allodynia, reduced the activation of ERK and p38-MAPK, and decreased the expression of pro-inflammatory cytokines in the TG. Furthermore, intra-TG injection of the TLR8 agonist VTX-2337 induced pain hypersensitivity. VTX-2337 also increased the intracellular Ca 2+ concentration, induced the activation of ERK and p38, and increased the expression of pro-inflammatory cytokines in the TG. These data indicate that TLR8 contributes to the maintenance of TNP through increasing MAPK-mediated neuroinflammation. Targeting TLR8 signaling may be effective for the treatment of TNP.

Activating Transcription Factor 6 Contributes to Functional Recovery After Spinal Cord Injury in Adult Zebrafish - Zhe Ji; Zhi-Lan Zhou; Qin Hao; Lin Zhao; Chun Cui; Shu-Bing Huang; Yan-Ling Yang; Yan-Qin Shen (Journal of Molecular Neuroscience, 2021)

The role of lime in dredged mud dewatered by a plate and frame filter press and potential substitutes - Yan Cui; Wei Zhu; Silin Wu; Jiming Liu; Hao Hou; Naixi Lin (Environmental Science and Pollution Research, 2021)

Comparative understanding of metal hyperaccumulation in plants: a mini-review - Jia-Shi Peng; Yu-Hao Guan; Xian-Jing Lin; Xiao-Jing Xu; Lu Xiao; Hai-Hua Wang; Shuan Meng (Environmental Geochemistry and Health, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

Azure-winged Magpies Cyanopica cyanus passed the tasks on the Uzgiris-Hunt scale of object permanence - Lin Wang; Yunchao Luo; Abudusaimaiti Maierdiyali; Hao Chang; Sana Ullah; Zhongqiu Li (Journal of Ornithology, 2021)

Retraction Note: Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis - Junjie Yin; Qingsong Yin; Bo Liang; Ruihua Mi; Hao Ai; Lin Chen; Xudong Wei (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Model test on support scheme for carbonaceous slate tunnel in high geostress zone at high depth - Zhi-gang Tao; Shu-lin Ren; Gan Li; Hao-tian Xu; Sen-lin Luo; Man-chao He (Journal of Mountain Science, 2021)

Rapid diagnosis of Ralstonia solanacearum infection sweet potato in China by loop-mediated isothermal amplification - Huawei Li; Hong Zhang; Zhonghua Liu; Zhijian Lin; Yongxiang Qiu; Hao Tang; Sixin Qiu (Archives of Microbiology, 2021)

Correction to: A Chromosomal-scale Reference Genome of the Kelp Grouper Epinephelus moara - Qian Zhou; Haoyang Gao; Hao Xu; Haoran Lin; Songlin Chen (Marine Biotechnology, 2021)

A Chromosomal-scale Reference Genome of the Kelp Grouper Epinephelus moara - Qian Zhou; Haoyang Gao; Hao Xu; Haoran Lin; Songlin Chen (Marine Biotechnology, 2021)

High expression of NEK2 promotes gastric cancer progression via activating AKT signaling - Hao Wan; Lin Xu; Huangbin Zhang; Feixiang Wu; Weiqiang Zeng; Taiyuan Li (Journal of Physiology and Biochemistry, 2021)

18 Additional Amino Acids of the Signal Peptide of the Bombyx mori Nucleopolyhedrovirus GP64 Activates Immunoglobulin Binding Protein (BiP) Expression by RNA-seq Analysis - Na Liu; Jinshan Huang; Lin Liu; Frank Boadi; Yanhui Song; Zhongjian Guo; Xingjia Shen; Bifang Hao (Current Microbiology, 2021)

Sex-specific effects of cigarette smoking on caudate and amygdala volume and resting-state functional connectivity - Fuchun Lin; Xu Han; Yao Wang; Weina Ding; Yawen Sun; Yan Zhou; Hao Lei (Brain Imaging and Behavior, 2021)

Community structure of bacterioplankton and its relationship with environmental factors in the upper reaches of the Heihe River in Qinghai Plateau - Zhang Qian‐Qian; Jian Sheng‐Long; Li Ke‐Mao; Wu Zhen‐Bing; Guan Hong‐Tao; Hao Jin‐Wen; Wang Shu‐Yi; Lin Yao‐Yao; Wang Guo‐Jie; Li Ai‐Hua (Environmental Microbiology, 2021)
Summary Planktonic microorganisms play a key role in the biogeochemical processes of the aquatic system, and they may be affected by many factors. High‐throughput sequencing technology was used in this study to investigate and study the bacterioplankton community of water bodies in the upper reaches of the Heihe River Basin in Qinghai Plateau. Results showed that Proteobacteria, Firmicutes, Bacteroidetes and Actinobacteria are the predominant phyla in this river section, while the main genera are Thiomonas , Acidibacillus , Acidocella , Rhodanobacter , Acidithiobacter and Gallionella , which are autochthonous in the acid‐mine drainage. Additionally, total nitrogen, total phosphorus, permanganate index and pH are significantly correlated with the bacterioplankton abundance and are the main limiting factors for the spatial distribution of the bacterioplankton. PICRUSt inferred that the mainstream microbial assemblages had a higher abundance of KOs belong to metabolism of terpenoids and polyketides, while the tributary had higher abundance of KOs belong to the immune system. The relationship between bacterioplankton community composition and environmental factors in the Heihe River basin was discussed for the first time in this study, which provides a theoretical basis for the healthy, orderly development of the water environment in the Heihe River Basin.

The substrate‐dependent regulatory effects of the AfeI /R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles - Xue‐Yan Gao; Chang‐Ai Fu; Likai Hao; Xiu‐Feng Gu; Rui Wang; Jian‐Qiang Lin; Xiang‐Mei Liu; Xin Pang; Cheng‐Jia Zhang; Jian‐Qun Lin; Lin‐Xu Chen (Environmental Microbiology, 2021)
Summary A LuxI/R‐like quorum sensing (QS) system (AfeI/R) has been reported in the acidophilic and chemoautotrophic Acidithiobacillus spp. However, the function of AfeI/R remains unclear because of the difficulties in the genetic manipulation of these bacteria. Here, we constructed different afeI mutants of the sulfur‐ and iron‐oxidizer A . ferrooxidans , identified the N‐acyl homoserine lactones (acyl‐HSLs) synthesized by AfeI, and determined the regulatory effects of AfeI/R on genes expression, extracellular polymeric substance synthesis, energy metabolism, cell growth and population density of A . ferrooxidans in different energy substrates. Acyl‐HSLs‐mediated distinct regulation strategies were employed to influence bacterial metabolism and cell growth of A . ferrooxidans cultivated in either sulfur or ferrous iron. Based on these findings, an energy‐substrate‐dependent regulation mode of AfeI/R in A . ferrooxidans was illuminated that AfeI/R could produce different types of acyl‐HSLs and employ specific acyl‐HSLs to regulate specific genes in response to different energy substrates. The discovery of the AfeI/R‐mediated substrate‐dependent regulatory mode expands our knowledge on the function of QS system in the chemoautotrophic sulfur‐ and ferrous iron‐oxidizing bacteria, and provides new insights in understanding energy metabolism modulation, population control, bacteria‐driven bioleaching process, and the coevolution between the acidophiles and their acidic habitats.

Ca2+/Calmodulin-NOS/NO-TNFs Pathway Hallmarks the Inflammation Response of Oyster During Aerial Exposure - Hao Chen; Lusheng Xin; Lin Wang; Huan Zhang; Rui Liu; Hao Wang; Xue Qiao; Lingling Wang; Linsheng Song (Frontiers in Marine Science, 2021)
Aerial exposure (emersion) due to the periodical ebb and flow of tides is a major stressor for intertidal organisms and a key environmental factor in shaping their local communities. Oysters are among the most emersion-tolerant mollusk species and can survive for several days under aerial exposure. Noticeably, overwhelming inflammation responses could occur during the emersion stress. However, mechanisms beneath the activation and modulation of emersion-induced inflammation response have remained largely unknown. Ca 2+ is an important intracellular second messenger that plays indispensable roles in inflammation response by cooperation with calmodulin (CaM) genes. Here, we showed that intracellular Ca 2+ accumulates rapidly in oyster hemocytes during emersion stress along with the changes in the protein levels of three CaM genes, which function as intracellular sensors of Ca 2+ . As downstream effector of Ca 2+ /CaM complex, nitric oxide synthase (NOS) activity in hemocytes was enhanced during the emersion stress, facilitating a greater production of nitrite oxide (NO). Augmentation of NO concentration was associated with the increased mRNA expression levels of two oyster cytokines (CgTNFs) during aerial exposure. The robust accumulation of cytokines and severe injury of tissues in oysters have been regarded as potential cause and marker of their death in prolonged emersion stress. Here, both the expression levels of CgTNFs and the tissue injuries of oysters were attenuated when Ca 2+ /CaM complex or NOS activity were repressed in vivo during the emersion stress. These findings indicate that Ca 2+ /CaM-NOS/NO-CgTNFs pathway is critically involved in the emersion-induced inflammation response in oysters and plays a role in the resistance against long-term aerial exposure.

Identification and expression analysis of caffeoyl-coenzyme A O-methyltransferase family genes related to lignin biosynthesis in tea plant (Camellia sinensis) - Shi-Jia Lin; Ya-Zhuo Yang; Rui-Min Teng; Hao Liu; Hui Li; Jing Zhuang (Protoplasma, 2021)

Simulating warmer and drier climate increases root production but decreases root decomposition in an alpine grassland on the Tibetan plateau - Huiying Liu; Li Lin; Hao Wang; Zhenhua Zhang; Zijian Shangguan; Xiaojuan Feng; Jin-Sheng He (Plant and Soil, 2021)

Effects of shading on lignin biosynthesis in the leaf of tea plant (Camellia sinensis (L.) O. Kuntze) - Rui-Min Teng; Yong-Xin Wang; Hui Li; Shi-Jia Lin; Hao Liu; Jing Zhuang (Molecular Genetics and Genomics, 2021)

Improved control of Frankliniella occidentalis on greenhouse pepper through the integration of Orius sauteri and neonicotinoid insecticides - Qing-cai Lin; Hao Chen; Dirk Babendreier; Jin-ping Zhang; Feng Zhang; Xiao-yan Dai; Zuo-wen Sun; Zhao-peng Shi; Xiao-lin Dong; Guang-an Wu; Yi Yu; Li Zheng; et al. (Journal of Pest Science, 2021)

KASP markers to detect sub-chromosomal arm translocations between 6VS of Haynaldia villosa and 6AS of wheat - Shujie Zhang; Chaolan Fan; Jiangtao Luo; Lei Huang; Die Xie; Yazhou Li; Zhuo Chen; Bo Jiang; Shunzong Ning; Zhongwei Yuan; Lin Huang; Lianquan Zhang; et al. (Euphytica, 2021)

Biochar improves heavy metal passivation during wet anaerobic digestion of pig manure - Jun Wang; Xiaoxia Hao; Zile Liu; Zili Guo; Li Zhu; Bangjie Xiong; Dongmei Jiang; Linyuan Shen; Mingzhou Li; Bo Kang; Guoqing Tang; Lin Bai (Environmental Science and Pollution Research, 2021)

Tree ring width‐based January–March mean minimum temperature reconstruction from Larix gmelinii in the Greater Khingan Mountains, China since AD 1765 - Yangao Jiang; Chuan Liu; Junhui Zhang; Shijie Han; Cassius E. O. Coombs; Xiaoguang Wang; Junwei Wang; Lin Hao; Shengzhong Dong (International Journal of Climatology, 2021)
A ring‐width chronology of Larix gmelinii (LG) was developed in the northern Greater Khingan Mountains region of China. The response function analyses revealed that the local mean minimum temperature of January–March ( T 1–3 ) was the most limiting factor affecting the radial growth of LG trees. Based on correlation analysis, a reconstructed T 1–3 series from 1765 to 2013 was produced using standard ring‐width chronology. The reconstruction explained 41.2% of the total variance in recorded monthly mean minimum temperatures from 1960 to 2013. The reconstructed T 1–3 series had similar variability when compared with the May–September mean temperature reconstruction in Inner Mongolia (IM) and the February–March mean minimum temperature reconstruction in Yichun (YC). This reconstructed T 1–3 series also captured the severe snow disaster and cold wave events recorded from historical documents in Heilongjiang and Inner Mongolia. Spatial correlations between reconstructed series and gridded temperature data also provided a high level of confidence. In addition, significant relationships between the reconstructed T 1–3 series and the Pacific Decadal Oscillation (PDO), El Niño–Southern Oscillation (ENSO), North Atlantic Oscillation (NAO), solar activity, indicated that the T 1–3 variation might be influenced by large‐scale ocean–atmosphere interactions.

Adakitic rocks at convergent plate boundaries: Compositions and petrogenesis - Qiang Wang; Lulu Hao; Xiuzheng Zhang; Jinsheng Zhou; Jun Wang; Qiwei Li; Lin Ma; Long Zhang; Yue Qi; Gongjian Tang; Wei Dan; Jingjing Fan (Science China Earth Sciences, 2020)

Quantitative Determination of Glymphatic Flow Using Spectrophotofluorometry - Yu Zhang; Jian Song; Xu-Zhong He; Jian Xiong; Rong Xue; Jia-Hao Ge; Shi-Yu Lu; Die Hu; Guo-Xing Zhang; Guang-Yin Xu; Lin-Hui Wang (Neuroscience Bulletin, 2020)

Rockburst Risk Analysis During High-Hard Roof Breaking in Deep Mines - Qiming Zhang; Enyuan Wang; Xiaojun Feng; Yue Niu; Muhammad Ali; Song Lin; Hao Wang (Natural Resources Research, 2020)

The extract of aquatic macrophyte Carex cinerascens induced colony formation in bloom-forming cyanobacterium Microcystis aeruginosa - Lin Li; Xiao-ling Jing; Ling Wang; Zhi-gao Zeng; Wen-hong Chen; Jia-hao Zhai; Si-qin Qi (Environmental Science and Pollution Research, 2020)

Urbanization and carbon emission: causality evidence from the new industrialized economies - Khalid Khan; Chi-Wei Su; Ran Tao; Lin-Na Hao (Environment, Development and Sustainability, 2020)

Numerical study of the seismic performance and damage mitigation of steel–concrete composite rigid-frame bridge subjected to across-fault ground motions - Yuanzheng Lin; Zhouhong Zong; Kaiming Bi; Hong Hao; Jin Lin; Yiyan Chen (Bulletin of Earthquake Engineering, 2020)

Functional human brain connectivity during labor and its alteration under epidural analgesia - Fan-Pei Yang; An-Shine Chao; Sung-Han Lin; Anne Chao; Tzu-Hao Wang; Yao-Lung Chang; Hong-Shiu Chang; Jiun-Jie Wang (Brain Imaging and Behavior, 2020)

Overexpression of a multifunctional β-glucosidase gene from thermophilic archaeon Sulfolobus solfataricus in transgenic tobacco could facilitate glucose release and its use as a reporter - Chih-Hao Huang; Tzu-Ling Huang; Yu-Chang Liu; Ting-Chieh Chen; Shih-Ming Lin; Shyh-Yu Shaw; Ching-Chun Chang (Transgenic Research, 2020)

Stability analysis of open-pit gold mine slopes and optimization of mining scheme in Inner Mongolia, China - Shu-lin Ren; Zhi-gang Tao; Man-chao He; Shi-hui Pang; Meng-nan Li; Hao-tian Xu (Journal of Mountain Science, 2020)

Estimation of surface energy fluxes in the permafrost region of the Tibetan Plateau based on in situ measurements and the surface energy balance system model - Jimin Yao; Lianglei Gu; Cheng Yang; Hao Chen; Jiemin Wang; Yongjian Ding; Ren Li; Lin Zhao; Yao Xiao; Yongping Qiao; Jianzong Shi; Caiping Chen (International Journal of Climatology, 2020)
The surface energy balance is a key issue in land surface process research and important for studies of climate and hydrology. In this paper, the surface energy fluxes (net radiation, ground heat flux, sensible heat flux and latent heat flux) at the Tanggula (TGL) and Xidatan (XDT) sites were measured and the distributions of the regional surface energy fluxes on the Tibetan Plateau were obtained using a revised surface energy balance system (SEBS) model. The results show that the surface energy fluxes have obvious seasonal variations. At both sites, the sensible heat flux is highest in spring and lowest in summer, and the latent heat flux is highest in summer and lowest in winter. The high elevation, snow cover, freeze–thaw process, precipitation, vegetation and soil texture are important influencing factors for land surface energy fluxes. The time‐phase difference between the net radiation and ground heat flux for bare soils is estimated to be 2–3 hr. The ratio of ground heat flux and net radiation ranged from approximately 0.18 to 0.33, and a parameterization scheme for the remote sensing of ground heat flux over the Tibetan Plateau bare soil in summer is developed. The simulation results of the regional surface energy fluxes show that the distributions of surface parameters, such as vegetation, soil texture and soil moisture content, are important for understanding regional changes in the surface energy fluxes.

Mechanism of contractile dysfunction induced by serotonin in coronary artery in spontaneously hypertensive rats - Hao Wang; Xiao-Yan Gao; Fang Rao; Hui Yang; Zhao-Yu Wang; Lin Liu; Su-Juan Kuang; Qi Wu; Chun-Yu Deng; Jing-Song Xu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death - Mengyu Liu; Dexin Sui; Thomas Dexheimer; Stacy Hovde; Xiexiong Deng; Kuang-Wei Wang; Hsin Lian Lin; Hsiao-Tien Chien; Hye Kyong Kweon; Nora Sheen Kuo; Christopher A. Ayoub; Daniela Jimenez-Harrison; et al. (Molecular Neurobiology, 2020)

Identification and characterization of Diaporthe eres causing leaf blight disease on the medicinal herb Polygonatum sibiricum - Hang Tao; Hao Wang; Shen-Xin Huang; Ye Zhang; Zi-Hui Zhang; Wang Liu; Ning-Xue Shi; Feng Zhu; Zhao-Lin Ji; Xiao-Ren Chen (Journal of General Plant Pathology, 2020)

Ridge subduction, magmatism, and metallogenesis - Qiang Wang; Gongjian Tang; Lulu Hao; Derek Wyman; Lin Ma; Wei Dan; Xiuzheng Zhang; Jinheng Liu; Tongyu Huang; Chuanbing Xu (Science China Earth Sciences, 2020)

LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer’s disease - Chia-Hao Fan; Chia-Wei Lin; Hei-Jen Huang; Guey-Jen Lee-Chen; Ying-Chieh Sun; Wenwei Lin; Chiung-Mei Chen; Kuo-Hsuan Chang; Ming-Tsan Su; Hsiu Mei Hsieh-Li (Psychopharmacology, 2020)

Apical ectodermal ridge regulates three principal axes of the developing limb - Guo-hao Lin; Lan Zhang (Journal of Zhejiang University-SCIENCE B, 2020)

Identification of Prognostic Signatures of Alternative Splicing in Glioma - Yu Zeng; Peidong Zhang; Xizhao Wang; Ke Wang; Mingfeng Zhou; Hao Long; Jie Lin; Zhiyong Wu; Liang Gao; Ye Song (Journal of Molecular Neuroscience, 2020)

Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin - Shun-Cheng Chang; Chien-Ping Chiang; Chih-Hsin Lai; Po-Wen A. Du; Yu-Sin Hung; Yu-Hsuan Chen; Hui-Yu Yang; Hao-Yu Fang; Shiao-Pieng Lee; Hung-Jen Tang; Jehng-Kang Wang; Michael D. Johnson; et al. (Human Cell, 2020)

The gut-microbiota-testis axis mediated by the activation of the Nrf2 antioxidant pathway is related to prepuberal steroidogenesis disorders induced by di-(2-ethylhexyl) phthalate - Tian-Xin Zhao; Yue-Xin Wei; Jun-Ke Wang; Lin-Dong Han; Mang Sun; Yu-Hao Wu; Lian-Ju Shen; Chun-Lan Long; Sheng-De Wu; Guang-Hui Wei (Environmental Science and Pollution Research, 2020)

Evaluation of the production-living-ecology space function suitability of Pingshan County in the Taihang mountainous area, China - Shu-hui Yu; Wei Deng; You-xin Xu; Xia Zhang; Hao-lin Xiang (Journal of Mountain Science, 2020)

Evaluation of the Impacts of Formulation Parameters on the Pharmacokinetics and Bioequivalence of Risperidone Orodispersible Film: a Physiologically Based Pharmacokinetic Modeling Approach - Fang Chen; Hongrui Liu; Bing Wang; Zhou Yang; Yusheng Chen; Liuliu Yang; Bing Wang; Zheng Jiao; Hai-Shu Lin; Yingjun Quan; Hao Wang; Xiaoqiang Xiang (AAPS PharmSciTech, 2020)

Improving daily precipitation estimates for the Qinghai‐Tibetan plateau based on environmental similarity - Yudan Wang; Yunfeng Kong; Hao Chen; Lin Zhao (International Journal of Climatology, 2020)
Due to the scarcity of gauge observations and inaccuracy of satellite estimation, obtaining reliable daily precipitation estimates over the Qinghai‐Tibetan Plateau (QTP) remains challenging. In this article, an integrated scheme is developed based on the assumption that in a specific climatic region, the similarity of environmental conditions related to precipitation (SEP) in two locations is positively correlated to the similarities of occurrence and magnitude of precipitation between them. First, the QTP was divided into the northwestern arid, middle semi‐arid/semi‐humid, and southeastern humid climatic sub‐regions by grouping analysis. Second, based on modified weighted k‐nearest neighbour model, daily precipitation of target locations in these climatic sub‐regions were predicted by weighted regression of a group of gauge observations that have the largest SEP with the target locations. SEP was calculated by the following auxiliary environmental factors: longitude, latitude, elevation, Normalized Difference Vegetation Index, relative humidity, and CMORPH (Climate Prediction Center's morphing technique) daily precipitation estimates (original CMORPH). The validation results demonstrate the effectiveness of the proposed scheme. Compared with the original CMORPH and PDF‐calibrated CMORPH (CMORPH calibrated by probability density function matching plus optimal interpolation method) at daily, monthly, and yearly scales, the scheme improves the rain/no rain detection capacity and the accuracy of daily precipitation estimates. In addition, the daily precipitation estimates obtained from this scheme can present significant discrimination over specific geographic units, particularly the Qaidam Basin, the great bend of the Brahmaputra River, and Hengduan Mountain.

Menaquinone-7 production in engineered Escherichia coli - Quanxiu Gao; Hao Chen; Wenzhao Wang; Jianzhong Huang; Yong Tao; Baixue Lin (World Journal of Microbiology and Biotechnology, 2020)

Using High-resolution Remote Sensing Images to Detect Freshwater Ecosystem Changes – a New Perspective of Different Ecosystem Types and Shapes - Chen Lin; Hao Cheng; Chi Zhang; Yang Zhang; Liangjie Wang (Water Resources Management, 2020)

The dominant model analysis of Sirt3 genetic variants is associated with susceptibility to tuberculosis in a Chinese Han population - Tao Wu; Lin Jiao; Hao Bai; Xuejiao Hu; Minjin Wang; Zhenzhen Zhao; Hui Xue; Binwu Ying (Molecular Genetics and Genomics, 2020)

TNFSF13 upregulation confers chemotherapeutic resistance via triggering autophagy initiation in triple-negative breast cancer - Hui-Yu Lin; Chia-Hao Kuei; Hsun-Hua Lee; Che-Hsuan Lin; Yen-Lin Chen; Chi-Long Chen; Yuan-Feng Lin (Journal of Molecular Medicine, 2020)

Gene UCHL1 expresses specifically in mouse uterine decidual cells in response to estrogen - Lishuang Hao; Di Song; Mengfei Zhuang; Yan Shi; Lin Yu; Yaping He; Jian Wang; Tingting Zhang; Zhaogui Sun (Histochemistry and Cell Biology, 2020)

Future trends and guidance for the triple bottom line and sustainability: a data driven bibliometric analysis - Ming-Lang Tseng; Chia-Hao Chang; Chun-Wei Remen Lin; Kuo-Jui Wu; Qing Chen; Li Xia; Bing Xue (Environmental Science and Pollution Research, 2020)
This study conducts a comprehensive literature review of articles on the triple bottom line (TBL) published from January 1997 to September 2018 to provide significant insights and support to guide further discussion. There were three booms in TBL publications, occurring in 2003, 2011, and 2015, and many articles attempt to address the issue of sustainability by employing the TBL. This literature analysis includes 720, 132, and 58 articles from the Web of Science (WOS), Inspec, and Scopus databases, respectively, and reveals the gaps in existing research. To discover the barriers and points of overlap, these articles are categorized into six aspects of the TBL: economic, environmental, social, operations, technology, and engineering. Examining the top 3 journals in terms of published articles on each aspect reveals the research trends and gaps. The findings provide solid evidence confirming the argument that the TBL as currently defined is insufficient to cover the entire concept of sustainability. The social and engineering aspects still require more discussion to support the linkage of the TBL and to reinforce its theoretical basis. Additionally, to discover the gaps in the data sources, theories applied, methods adopted, and types of contributions, this article summarizes 82 highly cited articles covering each aspect. This article offers theoretical insights by identifying the top contributing countries, institutions, authors, keyword networks, and authorship networks to encourage scholars to push the current discussion further forward, and it provides practical insights to bridge the gap between theory and practice for enhancing the efficiency and effectiveness of improvements.

Characterization of bimetallic Fe/Ni nanoparticles supported by amphiphilic block copolymer and its application in removal of 1,1,1-trichloroethane in water - Kai Huang; Hao Bian; Meng Zhang; Cong Zhan; Can Li; Wei Zhang; Changzheng Cui; Qiang Lu; Kuangfei Lin; Jianhua Zhao (Environmental Science and Pollution Research, 2020)

Developing a USLE cover and management factor (C) for forested regions of southern China - Conghui Li; Lili Lin; Zhenbang Hao; Christopher J. Post; Zhanghao Chen; Jian Liu; Kunyong Yu (Frontiers of Earth Science, 2020)

The crucial role of bacterial laccases in the bioremediation of petroleum hydrocarbons - Yan Zhang; Dong-Fa Lin; Jun Hao; Zhi-Hao Zhao; Ying-Jiu Zhang (World Journal of Microbiology and Biotechnology, 2020)

Impaired Parahippocampal Gyrus–Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease - Lin Zhu; Zan Wang; Zhanhong Du; Xinyang Qi; Hao Shu; Duan Liu; Fan Su; Qing Ye; Xuemei Liu; Zheng Zhou; Yongqiang Tang; Ru Song; et al. (Neuroscience Bulletin, 2020)

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study - Shao-rui Hao; Ren Yan; Shan-yan Zhang; Jiang-shan Lian; Huan Cai; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Size Effect on Mechanical Properties of Rock-Like Materials with Three Joints - Tao Dong; Ping Cao; Qibin Lin; Fei Wang; Zhizhen Liu; Ji Hao; Yezhen Xie (Geotechnical and Geological Engineering, 2020)

Mixture of Pb, Zn and Cu on root permeability and radial oxygen loss in the mangrove Bruguiera gymnorrhiza - Hao Cheng; You-Shao Wang; Chang-Da Li; Zhi-Hong Ye; Shafi Muhammad; Mei-Lin Wu; Fun-Lin Sun (Ecotoxicology, 2020)

Dynamics of radial oxygen loss in mangroves subjected to waterlogging - Hao Cheng; Mei-Lin Wu; Chang-Da Li; Fu-Lin Sun; Cui-Ci Sun; You-Shao Wang (Ecotoxicology, 2020)

Distribution patterns and source identification for heavy metals in Mirs Bay of Hong Kong in China - Mei-Lin Wu; Hao Cheng; Hui Zhao; Fu-Lin Sun; Yu-Tu Wang; Jian-Ping Yin; Jiao Fei; Cui-Ci Sun; You-Shao Wang (Ecotoxicology, 2020)

Phytoplankton community, structure and succession delineated by partial least square regression in Daya Bay, South China Sea - Mei-Lin Wu; Yu-Tu Wang; Hao Cheng; Fu-lin Sun; Jiao Fei; Cui-Ci Sun; Jian-Ping Yin; Hui Zhao; You-Shao Wang (Ecotoxicology, 2020)

Generation of a porcine reproductive and respiratory syndrome virus expressing a marker gene inserted between ORF4 and ORF5a - Yuxu Wang; Wei He; Qingqing Li; Xin Xie; Nian Qin; Hao Wang; Jiabin Huang; Siyuan Lin; Kang Ouyang; Ying Chen; Weijian Huang; Zuzhang Wei (Archives of Virology, 2020)

Ancestral niche separation and evolutionary rate differentiation between sister marine flavobacteria lineages - Chun‐Xu Xue; Hao Zhang; He‐Yu Lin; Ying Sun; Danli Luo; Yongjie Huang; Xiao‐Hua Zhang; Haiwei Luo (Environmental Microbiology, 2020)
Summary Marine flavobacteria are specialists for polysaccharide degradation. They dominate in habitats enriched with polysaccharides, but are also prevalent in pelagic environments where polysaccharides are less available. These niches are likely occupied by distinct lineages, but evolutionary processes underlying their niche differentiation remain elusive. Here, genomic analyses and physiological assays indicate that the sister flavobacteria lineages Leeuwenhoekiella and Nonlabens likely explore polysaccharide‐rich macroalgae and polysaccharide‐poor pelagic niches respectively. Phylogenomic analyses inferred that the niche separation likely occurred anciently and coincided with increased sequence evolutionary rate in Nonlabens compared with Leeuwenhoekiella . Further analyses ruled out the known mechanisms likely driving evolutionary rate acceleration, including reduced selection efficiency, decreased generation time and increased mutation rate. In particular, the mutation rates were determined using an unbiased experimental method, which measures the present‐day populations and may not reflect ancestral populations. These data collectively lead to a new hypothesis that an ancestral and transient mutation rate increase resulted in evolutionary rate increase in Nonlabens . This hypothesis was supported by inferring that gains and losses of genes involved in SOS response, a mechanism known to drive transiently increased mutation rate, coincided with evolutionary rate acceleration. Our analyses highlight the evolutionary mechanisms underlying niche differentiation of flavobacteria lineages.

Drought-tolerant plant growth-promoting rhizobacteria isolated from jujube (Ziziphus jujuba) and their potential to enhance drought tolerance - Min Zhang; Lin Yang; Ruqian Hao; Xiaoxiong Bai; Ying Wang; Xuan Yu (Plant and Soil, 2020)

Pseudomonas syringae dual‐function protein Lon switches between virulence and metabolism by acting as both DNA ‐binding transcriptional regulator and protease in different environments - Canfeng Hua; Tingting Wang; Xiaolong Shao; Yingpeng Xie; Hao Huang; Jingui Liu; Weitong Zhang; Yingchao Zhang; Yiqing Ding; Lin Jiang; Xin Wang; Xin Deng (Environmental Microbiology, 2020)
Summary Lon, a member of the AAA+ protease family, plays vital roles in Type III secretion systems (T3SS), agglutination and colony shape in the model plant pathogen Pseudomonas syringae . Lon also functions as a transcriptional regulator in other bacterial species such as Escherichia coli and Brevibacillus thermoruber . To reveal the molecular mechanisms of Lon as a dual‐function protein in P . syringae , we studied Lon‐regulated genes by using RNA sequencing (RNA‐seq), chromatin immunoprecipitation sequencing (ChIP‐seq) and liquid chromatography–tandem mass spectrometry. As a transcriptional regulator, Lon directly regulated a group of genes (PSPPH_4788, gacA , fur , gntR , clpS , lon and glyA ) and consequently regulated their functions, such as 1‐dodecanol oxidation activity, motility, pyoverdine production, glucokinase activity, N‐end rule pathway, lon expression and serine hydroxymethyltransferase activity. Mass spectrometry results revealed that the expression levels of five T3SS proteins (such as HrcV, HrpW1) were higher in the ∆ lon strain than the wild‐type (WT) strain in KB. In MM, 12 metabolic proteins (such as AcdS and NuoI) showed lower levels in the ∆ lon strain than the WT strain. Taken together, these data demonstrate that the dual‐function protein Lon sophisticatedly regulates virulence and metabolism in P . syringa e.

The defective effect of starch branching enzyme IIb from weak to strong induces the formation of biphasic starch granules in amylose-extender maize endosperm - Wei He; Xiangguo Liu; Lingshang Lin; Ahui Xu; Dongyun Hao; Cunxu Wei (Plant Molecular Biology, 2020)

Beneficial consequences of Lupeol on middle cerebral artery-induced cerebral ischemia in the rat involves Nrf2 and P38 MAPK modulation - Zhiyuan Zhang; Chongfu Xu; Jiheng Hao; Meng Zhang; Zidong Wang; Tengkun Yin; Kai Lin; Weidong Liu; Qunlong Jiang; Zhongchen Li; Dan Wang; Zhiqi Mao; et al. (Metabolic Brain Disease, 2020)

Large paleo-rockslide induced by buckling failure at Jiasian in Southern Taiwan - Che-Ming Yang; Keng-Hao Kang; Shun-Hsing Yang; Kuo-Wei Li; Hui-Jung Wang; Yin-Tsan Lee; Kuei-Kun Lin; Yii-Wen Pan; Jyh-Jong Liao (Landslides, 2020)

Biomechanical Analysis to Determine the Most Effective Posture During Squats and Shallow Squats While Lifting Weights in Women - Yo Chen; Zheng-Yang Xie; Ko-Yin Huang; Hui-Ting Lin; Jia-Hao Chang (Journal of Medical and Biological Engineering, 2020)

Depositional sequences and microfacies of Lower Carboniferous strata in the Marsel block of the Chu-Sarysu Basin, Southern Kazakhstan - Yuan Wang; Changsong Lin; Yanda Sun; Jingyan Liu; Hao Li; Haiquan He; Qinglong Wang; Muye Ji; Manli Zhang; Bozhi Zhao; Zhiyuan Zhang (Carbonates and Evaporites, 2020)

Improving nutritional quality of rice for human health - Mingchao Zhao; Yongjun Lin; Hao Chen (Theoretical and Applied Genetics, 2020)

Estimation of ground temperatures in permafrost regions of the Qinghai-Tibetan Plateau from climatic variables - Guojie Hu; Lin Zhao; Ren Li; Xiaodong Wu; Tonghua Wu; Changwei Xie; Xiaofan Zhu; Junming Hao (Theoretical and Applied Climatology, 2020)

Detection of serum IgM and IgG for COVID-19 diagnosis - Ling Zhong; Junlan Chuan; Bo Gong; Ping Shuai; Yu Zhou; Yi Zhang; Zhilin Jiang; Dingding Zhang; Xiaoqi Liu; Shi Ma; Yi Huang; He Lin; et al. (Science China Life Sciences, 2020)

Clinical strategies for differentiating IgG4-related cholecystitis from gallbladder carcinoma to avoid unnecessary surgical resection - Rui Zhang; Hao-Ming Lin; Zhao-Xi Cai; Su-Juan Du; Hong Zeng; Lei-Bo Xu; Jie Wang; Chao Liu (Science China Life Sciences, 2020)

Resequencing 93 accessions of coffee unveils independent and parallel selection during Coffea species divergence - Lifang Huang; Xiaoyang Wang; Yunping Dong; Yuzhou Long; Chaoyun Hao; Lin Yan; Tao Shi (Plant Molecular Biology, 2020)

SLC9A4 in the organum vasculosum of the lamina terminalis is a [Na+] sensor for the control of water intake - Hiraki Sakuta; Chia-Hao Lin; Takeshi Y. Hiyama; Takashi Matsuda; Katsushi Yamaguchi; Shuji Shigenobu; Kenta Kobayashi; Masaharu Noda (Pflügers Archiv - European Journal of Physiology, 2020)

Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure - Jiang-shan Lian; Huan Cai; Shao-rui Hao; Xi Jin; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Shan-yan Zhang; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Removal of phenol by Isochrysis galbana in seawater under varying temperature and light intensity - Hao Li; Fanping Meng; Yuejie Wang; Yufei Lin (Journal of Oceanology and Limnology, 2020)

Geochemistry of continental alkali basalts in the Sabzevar region, northern Iran: implications for the role of pyroxenite in magma genesis - Mojtaba Rostami-Hossouri; Habibollah Ghasemi; Kwan-Nang Pang; J. Gregory Shellnutt; Mehdi Rezaei-Kahkhaei; Laicheng Miao; Mohsen Mobasheri; Yoshiyuki Iizuka; Hao-Yang Lee; Te-Hsien Lin (Contributions to Mineralogy and Petrology, 2020)

Prior Antiplatelet Therapy, Excluding Phosphodiesterase Inhibitor Is Associated with Poor Outcome in Patients with Spontaneous Intracerebral Haemorrhage - Zhuo-Hao Liu; Chi-Hung Liu; Po-Hsun Tu; Ping K. Yip; Ching-Chang Chen; Yu-Chi Wang; Nan-Yu Chen; Yu-Sheng Lin (Translational Stroke Research, 2020)

Correction to: AVE0991, a nonpeptide angiotensin-(1–7) mimic, inhibits angiotensin II–induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice - Hui Ma; Yu-Lin Wang; Nai-Hao Hei; Jun-Long Li; Xin-Ran Cao; Bo Dong; Wen-jiang Yan (Journal of Molecular Medicine, 2020)

AVE0991, a nonpeptide angiotensin-(1–7) mimic, inhibits angiotensin II–induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice - Hui Ma; Yu-Lin Wang; Nai-Hao Hei; Jun-Long Li; Xin-Ran Cao; Bo Dong; Wen-jiang Yan (Journal of Molecular Medicine, 2020)

Research on Gas Outburst Coal Seam Mining Technology Based on the Theory of Gob-Side Entry Retaining - Yongkui Shi; Xin Wang; Jian Hao; Jiahui Lin; Weijia Cheng; Jun Chen; Xiao Li (Geotechnical and Geological Engineering, 2020)

Cross-Strait climate change and agricultural product loss - Hsing-Chun Lin; Li-Chen Chou; Wan-Hao Zhang (Environmental Science and Pollution Research, 2020)

Alpine grassland plants grow earlier and faster but biomass remains unchanged over 35 years of climate change - Hao Wang; Huiying Liu; Guangmin Cao; Zhiyuan Ma; Yikang Li; Fawei Zhang; Xia Zhao; Xinquan Zhao; Lin Jiang; Nathan J. Sanders; Aimée T. Classen; Jin‐Sheng He (Ecology Letters, 2020)
Satellite data indicate significant advancement in alpine spring phenology over decades of climate warming, but corresponding field evidence is scarce. It is also unknown whether this advancement results from an earlier shift of phenological events, or enhancement of plant growth under unchanged phenological pattern. By analyzing a 35‐year dataset of seasonal biomass dynamics of a Tibetan alpine grassland, we show that climate change promoted both earlier phenology and faster growth, without changing annual biomass production. Biomass production increased in spring due to a warming‐induced earlier onset of plant growth, but decreased in autumn due mainly to increased water stress. Plants grew faster but the fast‐growing period shortened during the mid‐growing season. These findings provide the first in situ evidence of long‐term changes in growth patterns in alpine grassland plant communities, and suggest that earlier phenology and faster growth will jointly contribute to plant growth in a warming climate.

An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction - Mengxi Guo; Chengliang Zhou; Gufeng Xu; Lin Tang; Yechun Ruan; Ying Yu; Xianhua Lin; Dandan Wu; Hao Chen; Priscilla Yu; Luyang Jin; Yinyu Wang; et al. (Science China Life Sciences, 2020)

Southward subduction of the Bangong-Nujiang Tethys Ocean: insights from ca. 161–129 Ma arc volcanic rocks in the north of Lhasa terrane, Tibet - Yue Tang; Qing-Guo Zhai; Pei-Yuan Hu; Sun-Lin Chung; Xu-Chang Xiao; Hai-Tao Wang; Zhi-Cai Zhu; Wei Wang; Hao Wu; Hao-Yang Lee (International Journal of Earth Sciences, 2020)

A stochastic multi-objective optimization decision model for energy facility allocation: a case of liquefied petroleum gas station - Ming-Der Yang; Yi-Ping Chen; Chien-Tsung Wang; Ming-Jay Deng; Yu-Hao Lin; Ho-Wen Chen (Clean Technologies and Environmental Policy, 2020)

Global buckling prevention of reduced-core-length buckling-restrained braces: theoretical and numerical investigations - Jing-Zhong Tong; Yan-Lin Guo; Wen-Hao Pan; Min-Hui Shen; Peng Zhou (Bulletin of Earthquake Engineering, 2020)

Characterization of a novel echovirus 21 strain isolated from a healthy child in China in 2013 - Hongbo Liu; Shanri Cong; Danhan Xu; Keqin Lin; Xiaoqin Huang; Hao Sun; Zhaoqing Yang; Shaohui Ma (Archives of Virology, 2020)

A deep learning approach to conflating heterogeneous geospatial data for corn yield estimation: A case study of the US Corn Belt at the county level - Hao Jiang; Hao Hu; Renhai Zhong; Jinfan Xu; Jialu Xu; Jingfeng Huang; Shaowen Wang; Yibin Ying; Tao Lin (Global Change Biology, 2020)
Understanding large‐scale crop growth and its responses to climate change are critical for yield estimation and prediction, especially under the increased frequency of extreme climate and weather events. County‐level corn phenology varies spatially and interannually across the Corn Belt in the United States, where precipitation and heat stress presents a temporal pattern among growth phases (GPs) and vary interannually. In this study, we developed a long short‐term memory (LSTM) model that integrates heterogeneous crop phenology, meteorology, and remote sensing data to estimate county‐level corn yields. By conflating heterogeneous phenology‐based remote sensing and meteorological indices, the LSTM model accounted for 76% of yield variations across the Corn Belt, improved from 39% of yield variations explained by phenology‐based meteorological indices alone. The LSTM model outperformed least absolute shrinkage and selection operator (LASSO) regression and random forest (RF) approaches for end‐of‐the‐season yield estimation, as a result of its recurrent neural network structure that can incorporate cumulative and nonlinear relationships between corn yield and environmental factors. The results showed that the period from silking to dough was most critical for crop yield estimation. The LSTM model presented a robust yield estimation under extreme weather events in 2012, which reduced the root‐mean‐square error to 1.47 Mg/ha from 1.93 Mg/ha for LASSO and 2.43 Mg/ha for RF. The LSTM model has the capability to learn general patterns from high‐dimensional (spectral, spatial, and temporal) input features to achieve a robust county‐level crop yield estimation. This deep learning approach holds great promise for better understanding the global condition of crop growth based on publicly available remote sensing and meteorological data.

The potential of satellite remote sensing for monitoring the onset of volcanic activity on Taipei’s doorstep - Hai-Po Chan; Chung-Pai Chang; Tang-Huang Lin; Matthew Blackett; Hao Kuo-Chen; Andrew Tien-Shun Lin (International Journal of Remote Sensing, 2020)

Thermal properties of active layer in permafrost regions with different vegetation types on the Qinghai-Tibetan Plateau - Guojie Hu; Lin Zhao; Ren Li; Xiaodong Wu; Tonghua Wu; Changwei Xie; Xiaofan Zhu; Junming Hao (Theoretical and Applied Climatology, 2020)

RETRACTED ARTICLE: Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis - Junjie Yin; Qingsong Yin; Bo Liang; Ruihua Mi; Hao Ai; Lin Chen; Xudong Wei (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

TLR-2-mediated metabolic reprogramming participates in polyene phosphatidylcholine-mediated inhibition of M1 macrophage polarization - Ting-Ting Feng; Xiao-Ying Yang; Shan-Shan Hao; Fen-Fen Sun; Ye Huang; Qi-Si Lin; Wei Pan (Immunologic Research, 2020)

An accounting of the external environmental costs of coal in Inner Mongolia using the pollution damage method - Hao-Dong Lv; Jin-Sheng Zhou; Lin Yang; Yi-Ming Li; Lu Liu (Environment, Development and Sustainability, 2020)

Population genetic structure and phylogenetic analysis of gray’s pipefish, Halicampus grayi in the South China Sea - Yingying Wu; Xin Wang; Shuaishuai Liu; Hao Luo; Qiang Lin (Genes & Genomics, 2020)

Resource availability affects temporal variation of phytoplankton size structure in the Kuroshio east of Taiwan - Fan‐Sian Lin; Pei‐Chi Ho; Akash R. Sastri; Chung‐Chi Chen; Gwo‐Ching Gong; Sen Jan; Chih‐hao Hsieh (Limnology and Oceanography, 2020)
The on‐going discussion concerning how environmental factors determine phytoplankton size structure has centered around two hypotheses: (H1) The resource‐size relationship predicts that normalized biovolume size spectrum (NBSS) slopes for phytoplankton are progressively shallower with increasing resource availability and (H2) The temperature‐size relationship predicts that phytoplankton NBSS slopes steepen with increasing water temperature. To test these hypotheses, we examined 72 phytoplankton assemblage collections in the Kuroshio east of Taiwan. Total phytoplankton biomass was used as a proxy for resource availability instead of nutrients because nutrients are depleted and do not represent resource availability for oligotrophic seas. We found no significant relationship between NBSS slopes with temperature, providing little support for the temperature‐size rule. In contrast, a positive relationship between NBSS slopes and total biomass for most of the year lends general support to the resource‐size relationship, except during the winter and early spring. To explain this exception, we hypothesize that resource pulses occurring during the cold seasons are used more efficiently by small cells and promote faster growth of small relative to large phytoplankton because these pulses take place after a long period of resource depletion in oligotrophic seas; thus, the NBSS slopes become much steeper than would be expected from a positive resource‐size relationship. This deviation can be considered as nonsteady state in terms of phytoplankton size structure relative to resources. Nevertheless, we cannot rule out the possibility that grazing effects also play an important role in controlling phytoplankton size structure.

XG-PseU: an eXtreme Gradient Boosting based method for identifying pseudouridine sites - Kewei Liu; Wei Chen; Hao Lin (Molecular Genetics and Genomics, 2020)

Sarocladium species associated with rice in Taiwan - Jie-Hao Ou; Guo-Cih Lin; Chi-Yu Chen (Mycological Progress, 2020)

Modeling the impact of dam removal on the Formosan landlocked salmon in the context of climate change - Laurie Battle; Hao-Yen Chang; Chyng-Shyan Tzeng; Hsing-Juh Lin (Aquatic Sciences, 2020)

Temporal population variability in local forest communities has mixed effects on tree species richness across a latitudinal gradient - Tak Fung; Ryan A. Chisholm; Kristina Anderson‐Teixeira; Norm Bourg; Warren Y. Brockelman; Sarayudh Bunyavejchewin; Chia‐Hao Chang‐Yang; Rutuja Chitra‐Tarak; George Chuyong; Richard Condit; Handanakere S. Dattaraja; Stuart J. Davies; et al. (Ecology Letters, 2020)
Among the local processes that determine species diversity in ecological communities, fluctuation‐dependent mechanisms that are mediated by temporal variability in the abundances of species populations have received significant attention. Higher temporal variability in the abundances of species populations can increase the strength of temporal niche partitioning but can also increase the risk of species extinctions, such that the net effect on species coexistence is not clear. We quantified this temporal population variability for tree species in 21 large forest plots and found much greater variability for higher latitude plots with fewer tree species. A fitted mechanistic model showed that among the forest plots, the net effect of temporal population variability on tree species coexistence was usually negative, but sometimes positive or negligible. Therefore, our results suggest that temporal variability in the abundances of species populations has no clear negative or positive contribution to the latitudinal gradient in tree species richness.

Probiotic Clostridium butyricum Improves the Growth Performance, Immune Function, and Gut Microbiota of Weaning Rex Rabbits - Lei Liu; Dong Zeng; Mingyue Yang; Bin Wen; Jing Lai; Yi Zhou; Hao Sun; Lvcheng Xiong; Jie Wang; Yicen Lin; Kangcheng Pan; Bo Jing; et al. (Probiotics and Antimicrobial Proteins, 2019)

Transcriptome sequencing of Eospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen - Lulu Xu; Zhiqiang Hao; Jinyan Lin; Qiong Zhao; Baojun Zhang; Guanglin Li; Jianping He; Jingang Li (Molecular Biology Reports, 2019)

LA-ICP-MS zircon U-Pb age and Hf isotope data from the granitic rocks in the Iwakuni area, Southwest Japan: re-evaluation of emplacement order and the source magma - Tayyaba Mateen; Kazuaki Okamoto; Sun-Lin Chung; Kuo-Lung Wang; Hao-Yang Lee; Shuhei Abe; Yuji Mita; Hafiz U. Rehman; Masaru Terabayashi; Hiroshi Yamamoto (Geosciences Journal, 2019)

Model test for water inrush caused by karst caves filled with confined water in tunnels - Weimin Yang; Xin Yang; Zhongdong Fang; Shaoshuai Shi; Hao Wang; Lin Bu; Liping Li; Zongqing Zhou (Arabian Journal of Geosciences, 2019)

Evaluation of reanalysis air temperature products in permafrost regions on the Qinghai-Tibetan Plateau - Guojie Hu; Lin Zhao; Xiaodong Wu; Ren Li; Tonghua Wu; Youqi Su; Junming Hao (Theoretical and Applied Climatology, 2019)

Isolation and identification of the Raoultella ornithinolytica-ZK4 degrading pyrethroid pesticides within soil sediment from an abandoned pesticide plant - Xiaoqing Zhang; Xiangxiang Hao; Shanshan Huo; Wanzhong Lin; Xinxin Xia; Kuai Liu; Bihua Duan (Archives of Microbiology, 2019)

Permian felsic magmatism in the Neoproterozoic Nagar Parkar Igneous Complex of the Malani Igneous Suite: Evidence from zircon U–Pb age - Hafiz U. Rehman; Tahseenullah Khan; Hao‐Yang Lee; Sun‐Lin Chung; Mamoru Murata; M. Qasim Jan (Island Arc, 2019)
We report Permian ( ca . 272 Ma ±5.4 Ma) felsic dykes that intrude into the Neoproterozoic ( ca . 750 Ma) magmatic suite of the Nagar Parkar Igneous Complex (NPIC), the western extension of the Malani Igneous Suite (MIS). The NPIC consists of Neoproterozoic basement amphibolites and granites (riebeckite–aegirine gray granites and the biotite–hornblende pink granites), all of which are intruded by several generations of mafic and felsic dykes. Granitic magmatism occurred in the Late Neoproterozoic ( ca . 750 Ma) due to the subduction‐, followed by the rift‐related tectonic regime during the breakup of the Rodinia supercontinent. U–Th–Pb zircon and monazite CHIME age data of 700–800 Ma from the earlier generation porphyritic felsic dykes suggest the dyke intrusion was coeval or soon after the emplacement of the host granites. Our findings of Permian age orthophyric felsic dykes provide new insights for the prevalence of active tectonics in the MIS during late Paleozoic. Textural features and geochemistry also make the orthophyric dykes distinct from the early‐formed porphyritic dykes and the host granites. Our newly obtained age data combined with geochemistry, suggest the existence of magmatism along the western margin of India (peri‐Gondwana margin) during Permian. Like elsewhere in the region, the Permian magmatism in the NPIC could be associated with the rifting of the Cimmerian micro‐continents from the Gondwana.

Correction to: SPECT/CT imaging of apoptosis in aortic aneurysm with radiolabeled duramycin - Chengkai Hu; Hui Tan; Qingyu Lin; Mieradilijiang Abudupataer; Yun Zhao; Jun Li; Jiawei Gu; Dengfeng Cheng; Chunsheng Wang; Kai Zhu; Hao Lai (Apoptosis, 2019)

Potential value of autoantibodies as biomarkers of chronic graft-versus-host disease after allogeneic stem cell transplantation - Bing Hao; Song Gao; Yi-wen Sang; Lin Wang; Xue-qin Meng; Jing-ya You (Journal of Zhejiang University-SCIENCE B, 2019)

Evaluation of Coherence Between ECG and PPG Derived Parameters on Heart Rate Variability and Respiration in Healthy Volunteers With/Without Controlled Breathing - Hao-Yu Jan; Mei-Fen Chen; Tieh-Cheng Fu; Wen-Chen Lin; Cheng-Lun Tsai; Kang-Ping Lin (Journal of Medical and Biological Engineering, 2019)

Purification, identification and characterization of an esterase with high enantioselectivity to (S)-ethyl indoline-2-carboxylate - Yin-Jun Zhang; Chang-Sheng Chen; Hao-Tian Liu; Jia-Lin Chen; Ying Xia; Shi-Jin Wu (Biotechnology Letters, 2019)

SPECT/CT imaging of apoptosis in aortic aneurysm with radiolabeled duramycin - Chengkai Hu; Hui Tan; Qingyu Lin; Mieradilijiang Abudupataer; Yun Zhao; Jun Li; Jiawei Gu; Dengfeng Cheng; Chunsheng Wang; Kai Zhu; Hao Lai (Apoptosis, 2019)

Multi‐omic analyses of exogenous nutrient bag decomposition by the black morel Morchella importuna reveal sustained carbon acquisition and transferring - Hao Tan; Annegret Kohler; Renyun Miao; Tianhai Liu; Qiang Zhang; Bo Zhang; Lin Jiang; Yong Wang; Liyuan Xie; Jie Tang; Xiaolin Li; Lixu Liu; et al. (Environmental Microbiology, 2019)
Summary The black morel ( Morchella importuna Kuo, O'Donnell and Volk) was once an uncultivable wild mushroom, until the development of exogenous nutrient bag (ENB), making its agricultural production quite feasible and stable. To date, how the nutritional acquisition of the morel mycelium is fulfilled to trigger its fruiting remains unknown. To investigate the mechanisms involved in ENB decomposition, the genome of a cultivable morel strain ( M . importuna SCYDJ1‐A1) was sequenced and the genes coding for the decay apparatus were identified. Expression of the encoded carbohydrate‐active enzymes (CAZymes) was then analyzed by metatranscriptomics and metaproteomics in combination with biochemical assays. The results show that a diverse set of hydrolytic and redox CAZymes secreted by the morel mycelium is the main force driving the substrate decomposition. Plant polysaccharides such as starch and cellulose present in ENB substrate (wheat grains plus rice husks) were rapidly degraded, whereas triglycerides were accumulated initially and consumed later. ENB decomposition led to a rapid increase in the organic carbon content in the surface soil of the mushroom bed, which was thereafter consumed during morel fruiting. In contrast to the high carbon consumption, no significant acquisition of nitrogen was observed. Our findings contribute to an increasingly detailed portrait of molecular features triggering morel fruiting.

Visualizing DC morphology and T cell motility to characterize DC-T cell encounters in mouse lymph nodes under mTOR inhibition - Qiaoya Lin; Zheng Liu; Meijie Luo; Hao Zheng; Sha Qiao; Chenlu Han; Deqiang Deng; Zhan Fan; Yafang Lu; Zhihong Zhang; Qingming Luo (Science China Life Sciences, 2019)

A Fast Projection-Based Algorithm for Clustering Big Data - Yun Wu; Zhiquan He; Hao Lin; Yufei Zheng; Jingfen Zhang; Dong Xu (Interdisciplinary Sciences: Computational Life Sciences, 2019)

Scenario analysis of ETS revenue allocation mechanism of China: based on a dynamic CGE model - Hao Li; Yuhuan Zhao; Song Wang; Jiang Lin; Ye Cao; Qiaoling Shi; Ya Liu; Yanli Xiao; Junjie Li (Environmental Science and Pollution Research, 2019)

Phytotoxicity and oxidative effects of typical quaternary ammonium compounds on wheat (Triticum aestivum L.) seedlings - Yafei Li; Can Zhou; Shizhong Wang; Qingqi Lin; Zhuobiao Ni; Hao Qiu; Jean Louis Morel; Rongliang Qiu (Environmental Science and Pollution Research, 2019)

Seasonal Dynamics of Gastrointestinal Nematode Infections of Goats and Emergence of Ivermectin Resistance in Haemonchus contortus in Hubei Province, China - Wei Yuan; Ke Lu; Hao Li; Jinming Liu; Chuanchuan He; Jintao Feng; Xin Zhang; Yudan Mao; Yang Hong; Yu Zhou; Jun Lu; Yamei Jin; et al. (Acta Parasitologica, 2019)

Potential hypoglycemic effect of acetophenones from the root bark of Cynanchum wilfordii - Hao-Wen Jiang; Shan-Shan Gu; Lei Cao; Sheng-Shi Jiang; Jing Lin; Yan Chen; Ling Wang; He Jiao; Jing-Ya Li; Wei-Min Zhao; Jin-Long Li (Natural Product Research, 2019)

A breeding strategy targeting the secondary gene pool of bread wheat: introgression from a synthetic hexaploid wheat - Ming Hao; Lianquan Zhang; Laibin Zhao; Shoufen Dai; Aili Li; Wuyun Yang; Die Xie; Qingcheng Li; Shunzong Ning; Zehong Yan; Bihua Wu; Xiujin Lan; et al. (Theoretical and Applied Genetics, 2019)

Ethylene insensitive mutation increases Arabidopsis tolerance to Cd in NPR1-dependent manner - Yutong Zhou; Chuan Liu; Guangzhe Li; Lin Hao (Plant and Soil, 2019)

Differential Transcriptomic and Metabolomic Responses in the Liver of Nile Tilapia (Oreochromis niloticus) Exposed to Acute Ammonia - Zong Xian Zhu; Dan Li Jiang; Bi Jun Li; Hui Qin; Zi Ning Meng; Hao Ran Lin; Jun Hong Xia (Marine Biotechnology, 2019)

Effects of exogenous putrescine on the ultrastructure of and calcium ion flow rate in lettuce leaf epidermal cells under drought stress - Xu Zhu; Lin Wang; Rui Yang; Yingyan Han; Jinghong Hao; Chaojie Liu; Shuangxi Fan (Horticulture, Environment, and Biotechnology, 2019)

Enzyme and pH dual-responsive avermectin nano-microcapsules for improving its efficacy - Guanghua Liu; Guanquan Lin; Xida Lin; Hongjun Zhou; Huayao Chen; Li Hao; Xinhua Zhou (Environmental Science and Pollution Research, 2019)

Environment‐ and trait‐mediated scaling of tree occupancy in forests worldwide - Haibao Ren; Petr Keil; Xiangcheng Mi; Keping Ma; Zhanqing Hao; Wanhui Ye; Luxiang Lin; Renato Valencia; Christine Dawn Fletcher; Duncan W. Thomas; Robert W. Howe; James Lutz; et al. (Global Ecology and Biogeography, 2019)
Aim The relationship between the proportion of sites occupied by a species and the area of a site [occupancy–area relationship (OAR)] offers key information for biodiversity management and has long fascinated ecologists. We quantified the variation in OAR for 3,157 woody species in 17 forest plots worldwide and tested the relative importance of environment and species traits for explaining this variation and evaluated overall model predictive ability. Location Global. Time period Early 21st century. Major taxa studied Woody plants. Methods We used mixed‐effect regression to examine the observed shape of the OAR (its “slope”) against species‐specific and plot‐wide predictors: coarse‐grain occupancy, tree size, plot species richness, energy availability and topographic complexity. Results We found large variation in OAR slopes, and the variation was strongest among species within plots. The OAR slopes showed a latitudinal trend and were steeper near the equator. As predicted, coarse‐grain occupancy and tree size negatively affected OAR slopes, whereas species richness had a positive effect and explained most of the variance between plots. Although hypothesized directionalities were broadly confirmed, traits and environment had relatively limited overall predictive power. Main conclusions These results document the variation of the OAR for 3,157 species at near‐global extent. We found a latitudinal gradient in OAR slopes and confirmed key hypothesized predictors. But at this global extent and over the large set of species analysed, the remaining unexplained variation in OAR slopes was substantial. Nevertheless, this large‐scale empirical analysis of the OAR offers an initial step towards a more general use of OARs for the fine‐scale prediction of species distributions and abundance.

Perspective: Something Old, Something New? Review of Wasting and Other Mortality in Asteroidea (Echinodermata) - Ian Hewson; Brooke Sullivan; Elliot W. Jackson; Qiang Xu; Hao Long; Chenggang Lin; Eva Marie Quijano Cardé; Justin Seymour; Nachshon Siboni; Matthew R. L. Jones; Mary A. Sewell (Frontiers in Marine Science, 2019)

Expression patterns of alpha-amylase and beta-amylase genes provide insights into the molecular mechanisms underlying the responses of tea plants (Camellia sinensis) to stress and postharvest processing treatments - Chuan Yue; Hongli Cao; Hongzheng Lin; Juan Hu; Yijun Ye; Jiamin Li; Zhilong Hao; Xinyuan Hao; Yun Sun; Yajun Yang; Xinchao Wang (Planta, 2019)

QTL Mapping for Red Blotches in Malaysia Red Tilapia (Oreochromis spp.) - Bi Jun Li; Zong Xian Zhu; Xiao Hui Gu; Hao Ran Lin; Jun Hong Xia (Marine Biotechnology, 2019)

Acoustic Emission-Feedback Planar Ultrasound System for Localized Blood–Brain Barrier Opening Monitoring - Chih-Hung Tsai; Ko-Ting Chen; Yu-Xian Lin; Yu-Chien Lin; Wen-Shiang Chen; Claude Inserra; Hao-Li Liu (Journal of Medical and Biological Engineering, 2019)

Hysteretic performance of inverted-V patterned BRB systems considering vertical pre-compression effects - Jing-Zhong Tong; Yan-Lin Guo; Wen-Hao Pan; Peng Zhou; Meng-Zheng Wang (Bulletin of Earthquake Engineering, 2019)

Fluids discrimination by ray-path elastic impedance inversion: A successful case from Sulige tight gas field - Da-Xing Wang; Hao-Fan Wang; Jin-Feng Ma; Yong-Gang Wang; Na Zhang; Lin Li (Applied Geophysics, 2019)

Primary Productivity Dynamics in the Summer Arctic Ocean Confirms Broad Regulation of the Electron Requirement for Carbon Fixation by Light-Phytoplankton Community Interaction - Yuanli Zhu; David J. Suggett; Chenggang Liu; Jianfeng He; Longshan Lin; Fengfeng Le; Joji Ishizaka; Joaquim Goes; Qiang Hao (Frontiers in Marine Science, 2019)

Functional characterization of GI and CO homologs from Eriobotrya deflexa Nakai forma koshunensis - Ling Zhang; Yuanyuan Jiang; Yunmei Zhu; Wenbing Su; Ting Long; Tianqi Huang; Jiangrong Peng; Hao Yu; Shunquan Lin; Yongshun Gao (Plant Cell Reports, 2019)

Cover Image - Theeraporn Pulpipat; Kuo‐Hua Lin; Ying‐Hao Chen; Pei‐Chi Wang; Shih‐Chu Chen (Journal of Fish Diseases, 2019)

Molecular characterization and pathogenicity of Francisella noatunensis subsp. orientalis isolated from cultured tilapia ( Oreochromis sp.) in Taiwan - Theeraporn Pulpipat; Kuo‐Hua Lin; Ying‐Hao Chen; Pei‐Chi Wang; Shih‐Chu Chen (Journal of Fish Diseases, 2019)
Francisella noatunensis subsp. orientalis is a causative agent of systemic granulomatous disease in tilapia. The present study was designed to understand the genetic and phenotypic diversities among Taiwanese Fno isolates obtained from tilapia ( n = 17) and green Texas cichlid ( Herichthys cyanoguttatus ) ( n = 1). The enzymatic profiles of the isolates were studied using the API ZYM system. Phylogenetic tree analysis of the 16S rRNA and housekeeping gene and pulsed‐field gel electrophoresis (PFGE) were carried out to determine the genotypic characters of all isolates. The phylogenetic tree showed similarity of 99%–100% nucleotide sequences of 16S rRNA and housekeeping genes compared to the Fno references genes from GenBank database. Comparatively, the results revealed an identical profile of enzymatic and PFGE pattern which was distincted from that of F. philomiragia . To understand the pathogenicity, the isolates were intraperitoneal injected to tilapia the gross lesions were observed concomitant with natural outbreak. Median lethal dose upon Nile tilapia and red tilapia were 9.06 × 10 3 CFU/fish and 2.08 × 10 2 CFU/fish, respectively. Thus, our data provide understanding the epidemiology of Taiwanese Fno isolates, and help in development of future control and prevention.

Multiple abiotic and biotic pathways shape biomass demographic processes in temperate forests - Zuoqiang Yuan; Arshad Ali; Tommaso Jucker; Paloma Ruiz‐Benito; Shaopeng Wang; Lin Jiang; Xugao Wang; Fei Lin; Ji Ye; Zhanqing Hao; Michel Loreau (Ecology, 2019)
Forests play a key role in regulating the global carbon cycle, and yet the abiotic and biotic conditions that drive the demographic processes that underpin forest carbon dynamics remain poorly understood in natural ecosystems. To address this knowledge gap, we used repeat forest inventory data from 92,285 trees across four large permanent plots (4–25 ha in size) in temperate mixed forests in northeast China to ask the following questions: (1) How do soil conditions and stand age drive biomass demographic processes? (2) How do vegetation quality (i.e., functional trait diversity and composition) and quantity (i.e., initial biomass stocks) influence biomass demographic processes independently from soil conditions and stand age? (3) What is the relative contribution of growth, recruitment, and mortality to net biomass change? Using structural equation modeling, we showed that all three demographic processes were jointly constrained by multiple abiotic and biotic factors and that mortality was the strongest determinant on net biomass change over time. Growth and mortality, as well as functional trait diversity and the community‐weighted mean of specific leaf area (CWM SLA ), declined with stand age. By contrast, high soil phosphorous concentrations were associated with greater functional diversity and faster dynamics (i.e., high growth and mortality rates), but associated with lower CWM SLA and initial biomass stock. More functionally diverse communities also had higher recruitment rates, but did not exhibit faster growth and mortality. Instead, initial biomass stocks and CWM SLA were stronger predictors of biomass growth and mortality, respectively. By integrating the full spectrum of abiotic and biotic drivers of forest biomass dynamics, our study provides critical system‐level insights needed to predict the possible consequences of regional changes in forest diversity, composition, structure and function in the context of global change.

Identifying a Long QTL Cluster Across chrLG18 Associated with Salt Tolerance in Tilapia Using GWAS and QTL-seq - Dan Li Jiang; Xiao Hui Gu; Bi Jun Li; Zong Xian Zhu; Hui Qin; Zi ning Meng; Hao Ran Lin; Jun Hong Xia (Marine Biotechnology, 2019)

l-Carnitine inhibits the senescence-associated secretory phenotype of aging adipose tissue by JNK/p53 pathway - Lian-wei Yang; Ming Song; Yu-lin Li; Ya-peng Liu; Chun Liu; Lu Han; Zhi-hao Wang; Wei Zhang; Yan-qiu Xing; Ming Zhong (Biogerontology, 2019)

Fish feeding groups, food selectivity, and diet shifts associated with environmental factors and prey availability along a large subtropical river, China - Sai Wang; Jin-Peng Tang; Lin-Hui Su; Jing-Jing Fan; Hao-Yen Chang; Tuan-Tuan Wang; Lin Wang; Hsing-Juh Lin; Yang Yang (Aquatic Sciences, 2019)

Classification and 3-D distribution of upper layer water masses in the northern South China Sea - Jia Zhu; Quanan Zheng; Jianyu Hu; Hongyang Lin; Dewen Chen; Zhaozhang Chen; Zhenyu Sun; Liyan Li; Hao Kong (Acta Oceanologica Sinica, 2019)

Contribution of atmospheric moisture transport to winter Arctic warming - Mingju Hao; Yong Luo; Yanluan Lin; Zongci Zhao; Lei Wang; Jianbin Huang (International Journal of Climatology, 2019)
Atmospheric moisture transport (AMT) is known to have an influence on the winter Arctic surface air temperature (SAT). However, a systematic investigation involving a verification of the physical linkages and spatial sensitivity within the Arctic, as well as a quantification of such contribution is still lacking. Our work first verifies the variation coherence between AMT and the SAT over the winters of 1979–2015, based on multiple data sets. Climate model projections reveal tendencies towards more frequent high values in both SAT and AMT from 2010 to 2065 relative to that from 1950 to 2005, as well as a high correlation coefficient between their detrended series. Then, a composite analysis is applied based on different AMT values. During high‐AMT episodes, enhanced AMT intrudes into the Arctic, with the Norwegian Sea as the gateway, and further induces unevenly distributed warming inside the Arctic. The greatest warming occurs in the Barents‐Kara Sea, which is tightly associated with the altered atmospheric moisture content and its subsequent changes of surface radiation balance. In addition, the intruding moisture can induce latent heat release and sea ice melting, which also influences the warming. Furthermore, by conducting numerical model experiments in the winter of 2012/2013, a total warming effect of 9.66 °C averaged across the Arctic for the original AMT is revealed. By setting different incremental AMT values in five cases, the leading role of AMT is found to switch in the 0.5MT case (the case wherein the AMT value is 0.5 times the original) from altering the atmospheric moisture content to producing precipitation. This finding suggests that evenly spaced AMTs result in the alleviation of SAT increases.

Investigation of Lactic Acid Bacteria Isolated from Giant Panda Feces for Potential Probiotics In Vitro - Qian Liu; Xueqin Ni; Qiang Wang; Zhirong Peng; Lili Niu; Meiling Xie; Yicen Lin; Yi Zhou; Hao Sun; Kangcheng Pan; Bo Jing; Dong Zeng (Probiotics and Antimicrobial Proteins, 2019)

Are glutamate transporters neuroprotective or neurodegenerative during cerebral ischemia? - Li-Nan Zhang; Liang Hao; Yu-Song Guo; Hai-Yan Wang; Lin-lin Li; Li-Zhe Liu; Wen-Bin Li (Journal of Molecular Medicine, 2019)

Attribute recognition model for risk assessment of water inrush - Jing Wang; Shu-cai Li; Li-ping Li; Peng Lin; Zhen-hao Xu; Cheng-lu Gao (Bulletin of Engineering Geology and the Environment, 2019)

Magnetic mineral diagenesis in sediments of saline lake Lop Nur - Wen Li; Gui-jin Mu; Yong-chong Lin; Hao-ze Song (Journal of Mountain Science, 2019)

2D Numerical Study of the Stability of Trench under Wave Action in the Immersing Process of Tunnel Element - Wei-Yun Chen; Cheng-Lin Liu; Lun-Liang Duan; Hao-Miao Qiu; Zhi-Hua Wang (Journal of Marine Science and Engineering, 2019)
The evaluation of the trench stability under the action of ocean waves is an important issue in the construction of an immersed tunnel. In this study, a two-dimensional coupling model of a wave-seabed-immersed tunnel is proposed for the dynamic responses of a trench under wave action in the immersing process of tunnel elements. The porous seabed is characterized by Biot consolidation equations. The k − ε model and RANS equation are adopted to achieve the flow field simulation, and the level set method (LSM) is used to capture the free surface between the water and air. The proposed numerical model is verified using the experimental data and analytical results. Then, the transient liquefaction and shear failure in the vicinity of the trench are discussed at two different conditions, namely, after the foundation groove is excavated and after the tunnel element is placed. The pore pressure amplitude on the weather side slope is demonstrated to be significantly smaller than that on the lee side slope. Also, the distribution of the surrounding flow field and pressure field change dramatically after the tunnel element is settled, leading to the significant changes of seabed stability.

Genome-wide analysis identified 17 new loci influencing intraocular pressure in Chinese population - Lulin Huang; Yuhong Chen; Ying Lin; Pancy O. S. Tam; Yilian Cheng; Yi Shi; Bo Gong; Fang Lu; Jialiang Yang; Haixin Wang; Yi Yin; Yong Cao; et al. (Science China Life Sciences, 2019)

Biodegradation of phenol by Isochrysis galbana screened from eight species of marine microalgae: growth kinetic models, enzyme analysis and biodegradation pathway - Yuejie Wang; Fanping Meng; Hao Li; Shilin Zhao; Qunqun Liu; Yufei Lin; Guoshan Wang; Jiangyue Wu (Journal of Applied Phycology, 2019)

Direct and indirect effects of climate on richness drive the latitudinal diversity gradient in forest trees - Chengjin Chu; James A. Lutz; Kamil Král; Tomáš Vrška; Xue Yin; Jonathan A. Myers; Iveren Abiem; Alfonso Alonso; Norm Bourg; David F.R.P. Burslem; Min Cao; Hazel Chapman; et al. (Ecology Letters, 2019)
Climate is widely recognised as an important determinant of the latitudinal diversity gradient. However, most existing studies make no distinction between direct and indirect effects of climate, which substantially hinders our understanding of how climate constrains biodiversity globally. Using data from 35 large forest plots, we test hypothesised relationships amongst climate, topography, forest structural attributes (stem abundance, tree size variation and stand basal area) and tree species richness to better understand drivers of latitudinal tree diversity patterns. Climate influences tree richness both directly, with more species in warm, moist, aseasonal climates and indirectly, with more species at higher stem abundance. These results imply direct limitation of species diversity by climatic stress and more rapid (co‐)evolution and narrower niche partitioning in warm climates. They also support the idea that increased numbers of individuals associated with high primary productivity are partitioned to support a greater number of species.

Complete Genome Sequence of Bacillus cereus CC-1, A Novel Marine Selenate/Selenite Reducing Bacterium Producing Metallic Selenides Nanomaterials - Lin Che; Weiping Xu; Jingjing Zhan; Lei Zhang; Lifen Liu; Hao Zhou (Current Microbiology, 2019)

Characterization of milk protein composition of the Yangtze finless porpoise - Xianyuan Zeng; Minmin Chen; Zhigang Liu; Daoping Yu; Shiang‐Lin Huang; Jiwei Yang; Fei Fan; Ding Wang; Yujiang Hao; Ghulam Nabi (Marine Mammal Science, 2019)

Cloning and Characterization of β-Fructosidase from Thermotoga neapolitana DSM4359 and Through the Degraded Glucoside - Yun-feng Bi; Lin-lin Xu; Ping Chen; Shan Jiang; Ming-hao Shen (Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 2018)

Effects of topographic factors and aboveground vegetation carbon stocks on soil organic carbon in Moso bamboo forests - Huiyun Fang; Biyong Ji; Xu Deng; Jiayang Ying; Guomo Zhou; Yongjun Shi; Lin Xu; Jixing Tao; Yufeng Zhou; Chong Li; Hao Zheng (Plant and Soil, 2018)

EGb761 improves the cognitive function of elderly db/db−/− diabetic mice by regulating the beclin-1 and NF-κB signaling pathways - Zhu-Fei Guan; Xiao-Ming Zhang; Ying-Hong Tao; Yu Zhang; Yan-Yan Huang; Gang Chen; Wei-Jun Tang; Gang Ji; Qi-Lin Guo; Ming Liu; Qian Zhang; Na-Na Wang; et al. (Metabolic Brain Disease, 2018)

Interhemispheric functional connectivity for Alzheimer’s disease and amnestic mild cognitive impairment based on the triple network model - Zheng-luan Liao; Yun-fei Tan; Ya-ju Qiu; Jun-peng Zhu; Yan Chen; Si-si Lin; Ming-hao Wu; Yan-ping Mao; Jiao-jiao Hu; Zhong-xiang Ding; En-yan Yu (Journal of Zhejiang University-SCIENCE B, 2018)

Constructing a Guided Filter by Exploiting the Butterworth Filter for ECG Signal Enhancement - Ming Liu; HuaQing Hao; Peng Xiong; Feng Lin; ZengGuang Hou; Xiuling Liu (Journal of Medical and Biological Engineering, 2018)

Offspring sex ratio and reproductive tactics of Leptocybe invasa (Hymenoptera: Eulophidae): testing the effect of environmental characteristics - Xia-Lin Zheng; Kai Lin; Zong-You Huang; Jun Li; Zhen-De Yang; Xiu-Hao Yang; Wen Lu (International Journal of Tropical Insect Science, 2018)

Contamination characteristics and potential environmental implications of heavy metals in road dusts in typical industrial and agricultural cities, southeastern Hubei Province, Central China - Da-Mao Xu; Jia-Quan Zhang; Bo Yan; Hao Liu; Li-Li Zhang; Chang-Lin Zhan; Li Zhang; Ping Zhong (Environmental Science and Pollution Research, 2018)

The influences of industrial gross domestic product, urbanization rate, environmental investment, and coal consumption on industrial air pollutant emission in China - Wei-yu Zhou; Wen-lin Yang; Wen-xin Wan; Jing Zhang; Wei Zhou; Hao-shen Yang; Hua Yang; Hong Xiao; Shi-huai Deng; Fei Shen; Ying-jun Wang (Environmental and Ecological Statistics, 2018)

Traditional Chinese Medicine in Multiple Sclerosis: Theory and Practice - Hao Chen; Xiaomeng Ma; Lei Si; Zhaoyu Chen; Xiuli Lin; Yuewu Yang; Xiaohong Chen (Current Pharmacology Reports, 2018)

Study of monthly variations in primary production and their relationships with environmental factors in the Daya Bay based on a general additive model - Jianhua Kang; Hao Huang; Weiwen Li; Yili Lin; Xingqun Chen (Acta Oceanologica Sinica, 2018)

The combination of everolimus and terameprocol exerts synergistic antiproliferative effects in endometrial cancer: molecular role of insulin-like growth factor binding protein 2 - Angel Chao; Chiao-Yun Lin; Ren-Chin Wu; Yun-Shien Lee; Li-Yu Lee; Chia-Lung Tsai; Lan-Yan Yang; Hsuan Liu; Shu-Jen Chen; Tzu-Hao Wang; Chyong-Huey Lai (Journal of Molecular Medicine, 2018)

Identification of urban park activity intensity at different thermal environments and visible sky by using sound levels - Kang-Ting Tsai; Yu-Hao Lin (International Journal of Biometeorology, 2018)

Screening and Genome Sequencing of Deltamethrin-Degrading Bacterium ZJ6 - Xiangxiang Hao; Xiaoqing Zhang; Bihua Duan; Shanshan Huo; Wanzhong Lin; Xinxin Xia; Kuai Liu (Current Microbiology, 2018)

Detection, sequence analysis, and antibody prevalence of porcine deltacoronavirus in Taiwan - Tien-Huan Hsu; Hao-Ping Liu; Chieh-Yu Chin; Chinling Wang; Wan-Zhen Zhu; Bing-Lin Wu; Yu-Chung Chang (Archives of Virology, 2018)

Toward a higher yield: a wireless sensor network-based temperature monitoring and fan-circulating system for precision cultivation in plant factories - Joe-Air Jiang; Min-Sheng Liao; Tzu-Shiang Lin; Chen-Kang Huang; Cheng-Ying Chou; Shih-Hao Yeh; Ta-Te Lin; Wei Fang (Precision Agriculture, 2018)

Combined ultrasound with Fenton treatment for the degradation of carcinogenic polycyclic aromatic hydrocarbons in textile dying sludge - Jian-Hao Zhang; Hai-Yuan Zou; Xun-An Ning; Mei-Qing Lin; Chang-Min Chen; Tai-Cheng An; Jian Sun (Environmental Geochemistry and Health, 2018)

Activation of histamine H4 receptor suppresses the proliferation and invasion of esophageal squamous cell carcinoma via both metabolism and non-metabolism signaling pathways - Gong-Hao He; Jia-Qi Ding; Xin Zhang; Wen-Mang Xu; Xiao-Qian Lin; Mei-Jin Huang; Ju Feng; Ping Wang; Wen-Ke Cai (Journal of Molecular Medicine, 2018)

Genetic analysis and location of a resistance gene for Puccinia striiformis f. sp. tritici in wheat cultivar Zhengmai 7698 - Hao Li; Jing Feng; Xiaodan Xu; Ruiming Lin; Fengtao Wang; Shichang Xu (Journal of Genetics, 2018)

Diversity and evolution of Lactobacillus casei group isolated from fermented dairy products in Tibet - Jing Feng; Yujun Jiang; Mingyu Li; Siyu Zhao; Yanming Zhang; Xuesong Li; Hui Wang; Guangen Lin; Hao Wang; Tiejing Li; Chaoxin Man (Archives of Microbiology, 2018)

Geochronological and geochemical constraints on the origin of the Southeast Anatolian ophiolites, Turkey - A. Feyzi Bingöl; Melahat Beyarslan; Yu-Chin Lin; Hao-Yang Lee (Arabian Journal of Geosciences, 2018)

Soil infiltration processes of different underlying surfaces in the permafrost region on the Tibetan Plateau - Guo-jie Hu; Li-ming Tian; Lin Zhao; Xiao-dong Wu; Ren Li; Tong-hua Wu; Xiao-fan Zhu; Er-ji Du; Zhi-wei Wang; Jun-ming Hao; Wang-ping Li; Song-he Wang (Hydrological Sciences Journal, 2018)

A genome-wide association study on growth traits in orange-spotted grouper (Epinephelus coioides) with RAD-seq genotyping - Hui Yu; Xinxin You; Jia Li; Xinhui Zhang; Shuai Zhang; Shoujia Jiang; Xueqiang Lin; Hao-Ran Lin; Zining Meng; Qiong Shi (Science China Life Sciences, 2018)

Development and evaluation of a storm surge warning system in Taiwan - Mei-Ying Lin; Wen-Yih Sun; Ming-Da Chiou; Chih-Ying Chen; Hao-Yuan Cheng; Cheng-Hsin Chen (Ocean Dynamics, 2018)

Expression of BC1 Impairs Spatial Learning and Memory in Alzheimer’s Disease Via APP Translation - Tongmei Zhang; Pei Pang; Zemin Fang; Yu Guo; Hao Li; Xinyan Li; Tian Tian; Xin Yang; Wenting Chen; Shu Shu; Na Tang; Jianhua Wu; et al. (Molecular Neurobiology, 2018)

The regulation of skeletal muscle fiber-type composition by betaine is associated with NFATc1/MyoD - Jingjing Du; Linyuan Shen; Peiwen Zhang; Zhendong Tan; Xiao Cheng; Jia Luo; Xue Zhao; Qiong Yang; Hao Gu; An’an Jiang; Jideng Ma; Qianzi Tang; et al. (Journal of Molecular Medicine, 2018)

A Novel Fluorescent Nanoparticle for Sensitive Detection of Cry1Ab Protein In Vitro and In Vivo - Xiao Xu; Hao Chen; Yuancheng Cao; Yongjun Lin; Jun’an Liu (Journal of Fluorescence, 2018)

Front Cover - James A. Lutz; Tucker J. Furniss; Daniel J. Johnson; Stuart J. Davies; David Allen; Alfonso Alonso; Kristina J. Anderson‐Teixeira; Ana Andrade; Jennifer Baltzer; Kendall M. L. Becker; Erika M. Blomdahl; Norman A. Bourg; et al. (Global Ecology and Biogeography, 2018)

Global importance of large‐diameter trees - James A. Lutz; Tucker J. Furniss; Daniel J. Johnson; Stuart J. Davies; David Allen; Alfonso Alonso; Kristina J. Anderson‐Teixeira; Ana Andrade; Jennifer Baltzer; Kendall M. L. Becker; Erika M. Blomdahl; Norman A. Bourg; et al. (Global Ecology and Biogeography, 2018)
Aim To examine the contribution of large‐diameter trees to biomass, stand structure, and species richness across forest biomes. Location Global. Time period Early 21st century. Major taxa studied Woody plants. Methods We examined the contribution of large trees to forest density, richness and biomass using a global network of 48 large (from 2 to 60 ha) forest plots representing 5,601,473 stems across 9,298 species and 210 plant families. This contribution was assessed using three metrics: the largest 1% of trees ≥ 1 cm diameter at breast height (DBH), all trees ≥ 60 cm DBH, and those rank‐ordered largest trees that cumulatively comprise 50% of forest biomass. Results Averaged across these 48 forest plots, the largest 1% of trees ≥ 1 cm DBH comprised 50% of aboveground live biomass, with hectare‐scale standard deviation of 26%. Trees ≥ 60 cm DBH comprised 41% of aboveground live tree biomass. The size of the largest trees correlated with total forest biomass ( r 2 = .62, p r 2 = .45, p r 2 = .33, p r 2 = .17, p = .002). The concentration of biomass in the largest 1% of trees declined with increasing absolute latitude ( r 2 = .46, p r 2 = .31, p r 2 = .26, p Main conclusions Because large‐diameter trees constitute roughly half of the mature forest biomass worldwide, their dynamics and sensitivities to environmental change represent potentially large controls on global forest carbon cycling. We recommend managing forests for conservation of existing large‐diameter trees or those that can soon reach large diameters as a simple way to conserve and potentially enhance ecosystem services.

Structural predication and antigenic analysis of Toxoplasma gondii ROP20 - Jian Zhou; Wanchun Wang; Pengxia Song; Lin Wang; Yali Han; Jingjing Guo; Zhen Hao; Xi Zhu; Qiong Zhou; Xiadong Du; Gang Lu; Shenyi He; et al. (Acta Parasitologica, 2018)
Toxoplasma gondii infects almost all the warm-blooded animals. ROP20 protein is expressed in the rhoptry of Toxoplasma gondii . In this study, the secondary structure of ROP20 was analyzed using SMART software. We constructed and analyzed the 3D model of ROP20 protein using SWISS-MODEL online procedure and Visual Molecular Dynamics (VMD) software. The structure analysis fully indicated that ROP20 protein is an important member of the ROP family. Furthermore, We used DNASTAR software and Epitope Database online service to analyze liner-B cell epitopes and T-cell epitopes of ROP20 protein. All the analysis results of ROP20 protein can provide positive information on treatment and vaccine for toxoplasmosis. Moreover, ROP20 gene was obtained from PCR, and a recombinant eukaryotic expression vector (pEGFP-C1-ROP20) was constructed in the following study. After restriction enzyme digestion, the constructed plasmid was transfected into HEK 293-T cells. The RT-PCR result indicated that the recombinant plasmid could transcribe successfully in HEK 293-T cell. The results of western blotting indicated the expressed proteins can be recognized by anti-STAg mouse sera.

Study on the Clinical Features and Prognosis of Penicilliosis marneffei Without Human Immunodeficiency Virus Infection - Ying-ge Wang; Jin-mei Cheng; Hai-bo Ding; Xi Lin; Guo-hao Chen; Mei Zhou; Sheng-nan Ye (Mycopathologia, 2018)

Social Isolation During Adolescence Induces Anxiety Behaviors and Enhances Firing Activity in BLA Pyramidal Neurons via mGluR5 Upregulation - Song Lin; Xin Li; Yi-Hua Chen; Feng Gao; Hao Chen; Neng-Yuan Hu; Lang Huang; Zheng-Yi Luo; Ji-Hong Liu; Qiang-Long You; Ya-Nan Yin; Ze-Lin Li; et al. (Molecular Neurobiology, 2018)

Identifying potentially common genes between dyslipidemia and osteoporosis using novel analytical approaches - Xu Lin; Cheng Peng; Jonathan Greenbaum; Zhang-Fang Li; Ke-Hao Wu; Zeng-Xin Ao; Tong Zhang; Jie Shen; Hong-Wen Deng (Molecular Genetics and Genomics, 2018)

Reciprocal Regulation of OmpR and Hfq and Their Regulatory Actions on the Vi Polysaccharide Capsular Antigen in Salmonella enterica Serovar Typhi - Ying Zhang; Lin Xia; Liping Lin; Hao Tang; George Osei-Adjei; Shungao Xu; Yiquan Zhang; Xinxiang Huang (Current Microbiology, 2018)

Brittleness characteristics of tight oil siltstones - Wen-Hui Tan; Jing Ba; Meng-Qiu Guo; Hui Li; Lin Zhang; Ting Yu; Hao Chen (Applied Geophysics, 2018)

An improved torque type gravity gradiometer with dynamic modulation - Jie Luo; Jia-Hao Xu; Qi Liu; Cheng-Gang Shao; Lin Zhu; Hui-Hui Zhao; Wei-Huang Wu (Acta Geodaetica et Geophysica, 2018)

Identification of antibiotic mycelia residue in protein rich feed using on near-infrared microscopy imaging - Yufei Lin; Zengling Yang; Hao Liang; Shouxue Li; Xia Fan; Zhiming Xiao (Food Additives & Contaminants: Part A, 2018)

Narrowing the surface temperature range in CMIP5 simulations over the Arctic - Mingju Hao; Jianbin Huang; Yong Luo; Xin Chen; Yanluan Lin; Zongci Zhao; Ying Xu (Theoretical and Applied Climatology, 2018)

Logistic model-based genetic analysis for kernel filling in a maize RIL population - Shuangyi Yin; Pengcheng Li; Yang Xu; Lin Xue; Derong Hao; Jun Liu; Tiantian Yang; Zefeng Yang; Chenwu Xu (Euphytica, 2018)

Correction to: Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures - Yun-Jian Dai; Zheng-Hao Xu; Bo Feng; Ceng-Lin Xu; Hua-Wei Zhao; Deng-Chang Wu; Wei-Wei Hu; Zhong Chen (Neuroscience Bulletin, 2018)

Effect of UGT2B7 genotypes on plasma concentration of valproic acid: a meta-analysis - Ping Wang; Xiao-Qian Lin; Wen-Ke Cai; Gui-Li Xu; Meng-Di Zhou; Mei Yang; Gong-Hao He (European Journal of Clinical Pharmacology, 2018)

Identification of genetic loci conferring partial resistance to southern corn rust through a genome-wide association study - Guangfei Zhou; Derong Hao; Yuxiang Mao; Qiuli Zhu; Guoqing Chen; Huhua Lu; Mingliang Shi; Xiaolan Huang; Zhenliang Zhang; Junyu Zhao; Lin Xue (European Journal of Plant Pathology, 2018)

Variations in the northern permafrost boundary over the last four decades in the Xidatan region, Qinghai–Tibet Plateau - Jing Luo; Fu-jun Niu; Zhan-ju Lin; Ming-hao Liu; Guo-an Yin (Journal of Mountain Science, 2018)

Determination of near real-time GNSS satellite clocks for the FORMOSAT-7/COSMIC-2 satellite mission - Tzu-Pang Tseng; Shu-Ya Chen; Kun-Lin Chen; Cheng-Yung Huang; Wen-Hao Yeh (GPS Solutions, 2018)

Ultrasonography of mammary glands in finless porpoises ( Neophocaena asiaeorientalis ) at different reproductive stages - Xianyuan Zeng; Shiang‐Lin Huang; Yujiang Hao; Ding Wang; Junhua Ji; Xiaojun Deng; Ghulam Nabi (Marine Mammal Science, 2018)

Discovery of potent and selective acetylcholinesterase (AChE) inhibitors: acacetin 7- O -methyl ether Mannich base derivatives synthesised from easy access natural product naringin - Hao-ran Liu; Xue Men; Xiao-hui Gao; Lin-bo Liu; Hao-qun Fan; Xin-hua Xia; Qiu-an Wang (Natural Product Research, 2018)

CyberConnector: a service-oriented system for automatically tailoring multisource Earth observation data to feed Earth science models - Ziheng Sun; Liping Di; Haosheng Hao; Xiaoqing Wu; Daniel Q. Tong; Chen Zhang; Cora Virgei; Hui Fang; Eugene Yu; Xicheng Tan; Peng Yue; Li Lin (Earth Science Informatics, 2018)