Rehabilitation of motor function in children with cerebral palsy based on motor imagery - Jiaxin Xie; Lin Jiang; Yanan Li; Baodan Chen; Fali Li; Yuanling Jiang; Dongrui Gao; Lili Deng; XuLin Lv; XianKun Ma; Gang Yin; Dezhong Yao; et al. (Cognitive Neurodynamics, 2021)

Sodium P-aminosalicylic Acid Attenuates Manganese-Induced Neuroinflammation in BV2 Microglia by Modulating NF-κB Pathway - Junyan Li; Yue Deng; Dongjie Peng; Lin Zhao; Yuanyuan Fang; Xiaojuan Zhu; Shaojun Li; Michael Aschner; Shiyan Ou; Yueming Jiang (Biological Trace Element Research, 2021)

Climate Suitability Assessment of Human Settlements for Regions along the Belt and Road - Yumei Lin; Peng Li; Zhiming Feng; Yanzhao Yang; Zhen You; Fuxin Zhu (Chinese Geographical Science, 2021)

Complete genome sequence of a putative novel ilarvirus isolated from Eleocharis dulcis - Lanqing Lv; Xinyang Wu; Jiajia Weng; Yuchao Lai; Kelei Han; Yuwen Lu; Jiejun Peng; Lin Lin; Shaofei Rao; Guanwei Wu; Jianping Chen; Hongying Zheng; et al. (Archives of Virology, 2021)

Retraction Note: Water ecological environment changes in Southwest China based on GIS and environmental monitoring - Zheng Lingling; Peng Zhu; Haitao Lin (Arabian Journal of Geosciences, 2021)

The Rapidly Evolving Fudu Estuary Sandbar Lagoon Landform on the East Coast of the Bohai Sea: Recent Changes and Mechanism - Lianjie Zhang; Jishun Yan; Bo Zhao; Xia Lin; Peng Wang; Chi Zhang; Yonghai Yu; Pan Zhang (Journal of Marine Science and Engineering, 2021)
The Fudu Estuary Sandbar Lagoon is one of the most representative sandbar-lagoon landforms in China, and has undergone drastic evolution in recent years, accompanied by increased coastal engineering activities. The evolution process and its control factors are studied through remote sensing interpretation and coastal sediment transport calculations. During 2010–2021, the sandbar quickly extended at an average speed of 49.5 m/a, but the annual growth has shown a decreasing trend in both area and width, and the shoreline has retreated by 25–45 m. The recent changes are the result of the combined action of natural conditions and human activities. Coastal sediment transport from west to east under the action of W-oriented waves is the natural cause of extension. An estuary dam and artificial island block the sediment transport path, and the material for the new growth of the sandbar comes from the erosion of its west side, which has directly caused the retreat and narrowing of the sandbar. The reduction in sediments from the river further aggravates the shrinkage. It is predicted that the sandbar will continue its eastward extension to connect with the coast in about 2–3 years. The erosion status is unlikely to change before the sediment supply is restored. Measures such as dismantling the estuary dam are recommended.

Associations of bisphenol exposure with the risk of gestational diabetes mellitus: a nested case–control study in Guangxi, China - Peng Tang; Jun Liang; Qian Liao; Huishen Huang; Xiaojing Guo; Mengrui Lin; Bihu Liu; Bincai Wei; Xiaoyun Zeng; Shun Liu; Dongping Huang; Xiaoqiang Qiu (Environmental Science and Pollution Research, 2021)

A New Instrumental Array in Sichuan, China, to Monitor Vibrations and Perturbations of the Lithosphere, Atmosphere, and Ionosphere - Chieh-Hung Chen; Yang-Yi Sun; Kai Lin; Chen Zhou; Rui Xu; Haiyin Qing; Yongxin Gao; Tao Chen; Fei Wang; Huaizhong Yu; Peng Han; Chi-Chia Tang; et al. (Surveys in Geophysics, 2021)

Redistribution of the lizardfish Harpadon nehereus in coastal waters of China due to climate change - Linlong Wang; Zhixin Zhang; Longshan Lin; Xin Peng; Li Lin; Bin Kang (Hydrobiologia, 2021)

The diversity of alkane-degrading bacterial communities in seagrass ecosystem of the South China Sea - Ying Zhang; Qingsong Yang; Juan Ling; Yanying Zhang; Weiguo Zhou; Manzoor Ahmad; Xiangcheng Lin; Liyun Lin; Qiuying Peng; Junde Dong (Ecotoxicology, 2021)

The distribution characteristics of β-propeller phytase genes in rhizosphere sediment provide insight into species specialty from phytic mineralization in subtropical and tropical seagrass ecosystems - Liyun Lin; Juan Ling; Qiuying Peng; Xiancheng Lin; Weiguo Zhou; Yanying Zhang; Qingsong Yang; Manzoor Ahamad; Ying Zhang; Cong Wang; Youshao Wang; Junde Dong (Ecotoxicology, 2021)

The Decision Strategies of Adolescents with Different Emotional Stabilities in Unfair Situations - Yajing Si; Lin Jiang; Chanlin Yi; Qi Zhang; Cunbo Li; Jing Yu; Peiyang Li; Qiang Liu; Feng Wan; Fali Li; Dezhong Yao; Peng Xu (Neuroscience Bulletin, 2021)

Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1 - Guang-Tong Jiang; Lin Shao; Shuo Kong; Meng-Liu Zeng; Jing-Jing Cheng; Tao-Xiang Chen; Song Han; Jun Yin; Wan-Hong Liu; Xiao-Hua He; Yu-Min Liu; Lanzi Gongga; et al. (Neuroscience Bulletin, 2021)

Jasmonic acid and hydrogen sulfide modulate transcriptional and enzymatic changes of plasma membrane NADPH oxidases (NOXs) and decrease oxidative damage in Oryza sativa L. during thiocyanate exposure - Xiao-Zhang Yu; Yun-Peng Chu; Hua Zhang; Yu-Juan Lin; Peng Tian (Ecotoxicology, 2021)

Development of a dual-labeled, hydrolysis probe-based, real-time quantitative PCR assay for detection of both genotypes of duck circovirus-1 (DuCV-1) and DuCV-2 - Lin Zhang; Wenming Jiang; Fuyou Zhang; Yang Li; Jinping Li; Shaobo Liang; Xiaohui Yu; Cheng Peng; Shuo Liu; Jingjing Wang; Shuhong Sun; Hualei Liu (Virus Genes, 2021)

Low-rank diffraction separation using an improved MSSA algorithm - Peng Lin; Jingtao Zhao; Suping Peng (Acta Geophysica, 2021)

Identification of a recessive gene YrZ15-1370 conferring adult plant resistance to stripe rust in wheat-Triticum boeoticum introgression line - Minghu Zhang; Xin Liu; Ting Peng; Dinghao Wang; Dongyu Liang; Hongyu Li; Ming Hao; Shunzong Ning; Zhongwei Yuan; Bo Jiang; Xuejiao Chen; Xue Chen; et al. (Theoretical and Applied Genetics, 2021)

Climate change impacts on China’s marine ecosystems - Bin Kang; Gretta T. Pecl; Longshan Lin; Peng Sun; Peidong Zhang; Yuan Li; Linlin Zhao; Xin Peng; Yunrong Yan; Chunyan Shen; Wentao Niu (Reviews in Fish Biology and Fisheries, 2021)

Integration of small RNAs, degradome, and transcriptome sequencing provides insights into the differences between Shizhu ginseng and Yuan ginseng - Mengyuan Peng; Yanlin Chen; Wenjuan Wang; Zhihua He; Wangqiang Dai; Zhiyun Lin; Zemin Yang; Mengjuan Gong; Yongqin Yin; Bin Han; Yu Zeng; Yingfang Wang (Journal of Plant Biochemistry and Biotechnology, 2021)
Panax ginseng is one of the most popular herbs which have been used as an important traditional Chinese medicine since ancient times. Yuan ginseng and Shizhu ginseng,which belong to P. ginseng , are widely used as substitutes for wild ginseng in clinical practice. Clinical practice has proved that the clinical efficacy of Shizhu ginseng is better than Yuan ginseng. However, current research cannot completely explain this phenomenon. Considering that small RNA may be one of the pharmacodynamic substances of P. ginseng , it is challenging to investigate differential miRNAs between Shizhu ginseng and Yuan ginseng. In this study, the transcriptome, small RNAome and degradome of P. ginseng were studied by high-throughput sequencing. A total of 63,875 unigenes and 43,950,137 small RNA clean reads were obtained from the roots of P. ginseng . Among 3206 differentially expressed genes, 1190 genes were up-regulated in Yuan ginseng when compared with Shizhu ginseng. 24 known differential miRNAs and 7 novel differential miRNAs were obtained. The 304 targets of 24 differentially expressed miRNA (17 known and 7 novel) families are mainly related to energy metabolism, biotic stress and disease immunity in ginseng itself. Through the association analysis of mRNA and miRNA, our work gives a better understanding of the difference between Yuan ginseng and Shizhu ginseng. Considering the cross-kingdom regulation of plant miRNAs, our results may provide a foundation for understanding the miRNA-dependent clinical efficacy in P. ginseng .

Applying Artificial Intelligence (AI) Techniques to Implement a Practical Smart Cage Aquaculture Management System - Chung-Cheng Chang; Jung-Hua Wang; Jenq-Lang Wu; Yi-Zeng Hsieh; Tzong-Dar Wu; Shyi-Chy Cheng; Chin-Chun Chang; Jih-Gau Juang; Chyng-Hwa Liou; Te-Hua Hsu; Yii-Shing Huang; Cheng-Ting Huang; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose This paper presents our team’s results to establish an AIoT smart cage culture management system. Methods According to the built system, the farmed field information is transmitted to the data platform of Ocean Cloud, and all collected data and analysis results can be applied to the cage culture field after the bigdata analysis. Results This management system successfully integrates AI and IoT technologies and is applied in cage culture. Using underwater biological analysis images and AI feeding as examples, this paper explains how the system integrates AI and IoT into a feasible framework that can constantly acquire information about the health status of fish, survival rate of fish, as well as the feed residuals. Conclusion The results of our research enable the aquaculture operators or owners to efficiently reduce the feed residual, monitor the growth of fish, and increase fish survival rate, thereby increasing the feed conversion rate.

Simulation study on the migration of F− in soil around Chagan Lake, China - Peng Xu; Jianmin Bian; Juanjuan Wu; Yihan Li; Jialin Li; Xia Zeng; Zuo Lin (Environmental Science and Pollution Research, 2021)

Acute associations between air pollution on premature rupture of membranes in Hefei, China - Chao Zhang; Sha Li; Gan-lan Guo; Jing-wen Hao; Peng Cheng; Li-lin Xiong; Shu-ting Chen; Ji-yu Cao; Yu-wen Guo; Jia-hu Hao (Environmental Geochemistry and Health, 2021)

Sodium P-aminosalicylic Acid Inhibits Manganese-Induced Neuroinflammation in BV2 Microglial Cells via NLRP3-CASP1 Inflammasome Pathway - Yuanyuan Fang; Dongjie Peng; Yuan Liang; Lili Lu; Junyan Li; Lin Zhao; Shiyan Ou; Shaojun Li; Michael Aschner; Yueming Jiang (Biological Trace Element Research, 2021)

RETRACTED ARTICLE:Water ecological environment changes in Southwest China based on GIS and environmental monitoring - Zheng Lingling; Peng Zhu; Haitao Lin (Arabian Journal of Geosciences, 2021)

Wogonin Accelerates Hematoma Clearance and Improves Neurological Outcome via the PPAR-γ Pathway After Intracerebral Hemorrhage - Jianfeng Zhuang; Yucong Peng; Chi Gu; Huihui Chen; Zheng Lin; Hang Zhou; Xiao Wu; Jianru Li; Xiaobo Yu; Yang Cao; Hanhai Zeng; Xiongjie Fu; et al. (Translational Stroke Research, 2021)

A Causal Role of the Cerebellum in Auditory Feedback Control of Vocal Production - Danhua Peng; Qing Lin; Yichen Chang; Jeffery A. Jones; Guoqing Jia; Xi Chen; Peng Liu; Hanjun Liu (The Cerebellum, 2021)

Hydro-mechanical Coupling Response Behaviors in Tunnel Subjected to a Water-Filled Karst Cave - Zhenhao Xu; Peng Lin; Huilin Xing; Dongdong Pan; Xin Huang (Rock Mechanics and Rock Engineering, 2021)

A Robust Adaptive Rank-Reduction Method for 3D Diffraction Separation and Imaging - Peng Lin; Jingtao Zhao; Suping Peng; Xiaoqin Cui; Chuangjian Li; Dongjing Xu (Pure and Applied Geophysics, 2021)

The relationship between anthocyanin accumulation and photoprotection in young leaves of two dominant tree species in subtropical forests in different seasons - Zheng-Chao Yu; Wei Lin; Xiao-Ting Zheng; Wah Soon Chow; Yan-Na Luo; Min-Ling Cai; Chang-Lian Peng (Photosynthesis Research, 2021)

The major photoprotective role of anthocyanins in leaves of Arabidopsis thaliana under long-term high light treatment: antioxidant or light attenuator? - Xiao-Ting Zheng; Zheng-Chao Yu; Jun-Wei Tang; Min-Ling Cai; Yi-Lin Chen; Cheng-Wei Yang; Wah Soon Chow; Chang-Lian Peng (Photosynthesis Research, 2021)

Photosynthetic compensation of non-leaf organ stems of the invasive species Sphagneticola trilobata (L.) Pruski at low temperature - Min-ling Cai; Wen-qiao Ding; Jun-jie Zhai; Xiao-ting Zheng; Zheng-chao Yu; Qi-lei Zhang; Xiao-hua Lin; Wah Soon Chow; Chang-lian Peng (Photosynthesis Research, 2021)

Using stratified Bayesian model averaging in probabilistic forecasts of precipitation over the middle and lower Yangtze River region - Haixia Qi; Xiefei Zhi; Tao Peng; YongQing Bai; Chunze Lin; Wen Chen (Meteorology and Atmospheric Physics, 2021)

Role of the microRNA-29 family in myocardial fibrosis - Changyan Li; Nan Wang; Peng Rao; Limeiting Wang; Di Lu; Lin Sun (Journal of Physiology and Biochemistry, 2021)

Risk of two common glandular cell-type cancers (breast and colorectal cancers) in Chinese occupational chefs: a nationwide ecological study in Taiwan - Pei-Chen Lin; Chiung‑Yu Peng; Chih‑Hong Pan; Jui-Ying Lee; Tusty-Jiuan Hsieh; Yun-Shiuan Chuang; Robert J. Turesky; Chia-Fang Wu; Ming-Tsang Wu (International Archives of Occupational and Environmental Health, 2021)

Conversion of rice husk into fermentable sugar and silica using acid-catalyzed ionic liquid pretreatment - YuJie Wang; Jing-yong Liu; Jian Sun; Sumarlin Shangdiar; Kassian T.T. Amesho; Yung-Chang Lin; Yen-Ping Peng; Ken-Lin Chang (Environmental Science and Pollution Research, 2021)

Occurrence of heavy metals, antibiotics, and antibiotic resistance genes in different kinds of land-applied manure in China - Jiajia Xue; Jianqiang Wu; Yaru Hu; Chenyan Sha; Shijie Yao; Peng Li; Kuangfei Lin; Changzheng Cui (Environmental Science and Pollution Research, 2021)

Effect of PAHs on nitrogen-fixing and sulfate-reducing microbial communities in seagrass Enhalus acoroides sediment - Juan Ling; Weiguo Zhou; Qingsong Yang; Xiancheng Lin; Ying Zhang; Manzoor Ahmad; Qinying Peng; Junde Dong (Archives of Microbiology, 2021)

Long‐term nitrogen input alters plant and soil bacterial, but not fungal beta diversity in a semiarid grassland - Weixing Liu; Lingli Liu; Xian Yang; Meifeng Deng; Zhou Wang; Pandeng Wang; Sen Yang; Ping Li; Ziyang Peng; Lu Yang; Lin Jiang (Global Change Biology, 2021)
Anthropogenic nitrogen (N) input is known to alter plant and microbial α‐diversity, but how N enrichment influences β‐diversity of plant and microbial communities remains poorly understood. Using a long‐term multilevel N addition experiment in a temperate steppe, we show that plant, soil bacterial and fungal communities exhibited different responses in their β‐diversity to N input. Plant β‐diversity decreased linearly as N addition increased, as a result of increased directional environmental filtering, where soil environmental properties largely explained variation in plant β‐diversity. Soil bacterial β‐diversity first increased then decreased with increasing N input, which was best explained by corresponding changes in soil environmental heterogeneity. Soil fungal β‐diversity, however, remained largely unchanged across the N gradient, with plant β‐diversity, soil environmental properties, and heterogeneity together explaining an insignificant fraction of variation in fungal β‐diversity, reflecting the importance of stochastic community assembly. Our study demonstrates the divergent effect of N enrichment on the assembly of plant, soil bacterial and fungal communities, emphasizing the need to examine closely associated fundamental components (i.e., plants and microorganisms) of ecosystems to gain a more complete understanding of ecological consequences of anthropogenic N enrichment.

7Be/210Pbxs Ratio-Derived Age and Residence Time of Suspended Sediments in Galveston Bay - Nicole Schmidt; Timothy Dellapenna; Peng Lin (Frontiers in Marine Science, 2021)
The winds associated with the passage of meteorological fronts cause waves that induce sediment remobilization/resuspension, especially within shallow estuaries such as Galveston Bay. The passage of cold fronts, collectively, on an annual to decadal basis, generate more sediment resuspension than most hurricanes and tropical storms. With a warming climate, the intensity of all meteorological events is shifting toward having greater impacts on these biologically productive environments. To better understand sediment resuspension within the bay, water samples were collected during frontal passages at two locations in Galveston Bay, including one location in the middle portion of the bay and another closer to the mouth of the bay. By collecting precipitation, water samples in both the middle and lower bay, and measuring the ratio of 7 Be/ 210 Pb xs in these samples; we quantified the residence times of total suspended sediment (TSS) in middle and lower Galveston Bay. Our results showed that suspended sediment age increased and percent of new suspended sediment decreased along the axis from the middle bay to the lower bay. This results from the initial introduction of newly labeled isotopes and suspended load coming from fluvial discharges which enter at the top of the bay and travel through the bay. The age of suspended sediment from the first sampling event was 70 ± 10 days, whereas the age in the second event was 16 ± 3 days greater. In the last sampling event, the age of suspended sediment event was 35 ± 7.4 days younger than the second, suggesting that the majority of suspended sediments was likely transported entirely out of the bay by the second cold front, prior to the final sampling event. This indicates that there are longer suspended sediment residence times when the water is trapped within the bay. Our estimated residence time of suspended sediments (51–105 days) suggest the particle-bound contaminants adsorb to suspended sediment may spend months suspended in the bay before exiting the bay or being accreted into the bay sediment column, increasing the exposure time of living organisms to various particle-bound contaminants.

Natural constituents from food sources as therapeutic agents for obesity and metabolic diseases targeting adipose tissue inflammation - Dan Li; Tian Zhang; Jinjian Lu; Cheng Peng; Ligen Lin (Critical Reviews in Food Science and Nutrition, 2021)

Identification of potential sex-related genes in Siniperca chuatsi - Qiaoying Zhu; Chong Han; Cheng Peng; Xingni Zhou; Chongwei Wang; Linqiang Han; Shuisheng Li; Guifeng Li; Haoran Lin; Yong Zhang (Journal of Oceanology and Limnology, 2021)

Actirhodobacter atriluteus gen. nov., sp. nov., isolated from the surface water of the Yellow Sea - Hua-Peng Xue; Dao-Feng Zhang; Lin Xu; Xiang-Ning Wang; Ai-Hua Zhang; Jian-Ke Huang; Chuang Liu (Antonie van Leeuwenhoek, 2021)

Molecular Level Characterization of Diatom and Coccolithophore-Associated Biopolymers That Are Binding 210Pb and 210Po in Seawater - Peng Lin; Chen Xu; Wei Xing; Peter H. Santschi (Frontiers in Marine Science, 2021)
Through a combination of selective extractions and molecular characterization techniques including Isoelectric Focusing Chromatography and Electrospray Ionization Fourier-Transform Ion Cyclotron Resonance Mass spectrometry, molecular structures of diatom ( Phaeodactylum tricornutum ) and coccolithophore ( Emiliania huxleyi )-associated biopolymers that are responsible for the distinct partitioning behavior between 210 Pb and 210 Po were determined. Our results show that diatom-derived biopolymers have distinctive elemental grouping distributions as compared to those excreted by the coccolithophore, with the former consisting of more heterogeneous elements (i.e., nitrogen, sulfur and phosphorus-containing organic compounds). For the coccolithophore culture, two 210 Pb-enriched biopolymers (non-attached exopolymeric substances and coccosphere shell-associated biopolymers) have a higher abundance of CHO-type compounds, suggesting CHO-only-type compounds as the main binding moieties for 210 Pb. In contrast, such association was not evident in the diatom culture. Different with 210 Pb, 210 Po enrichment in coccolithophore-derived attached exopolymeric substances and Fe-Mn-associated metabolites coincided with the higher abundance of nitrogen/sulfur-containing organic compounds in these two biopolymer fractions, suggesting the strong parallel of Po with the production of nitrogen-rich organic matter as well as sulfur-containing amino acids. These different associations between 210 Pb/ 210 Po and organic functional groups were further explored by separating 210 Pb or 210 Po-labeled coccolithophore-derived biopolymers via isoelectric focusing. This technique suggests that phosphate group-containing molecules but not the other molecules that contain heterogeneous elements (e.g., CHONS, CHON, and CHOS) as the strongest binding agents for 210 Pb, while the more hydrophobic (high protein to carbohydrate ratio) nitrogen/sulfur-enriched organic moieties acted as the main 210 Po-binding ligands. It is concluded that the deficiency of 210 Po with respect to 210 Pb can be influenced by the relative abundance of nitrogen/sulfur-enriched organic moieties to the nitrogen/sulfur-depleted organic compounds in the water column. This behavior constrains the application of 210 Po- 210 Pb approach to quantify the particulate organic carbon (POC) export flux in the ocean. It also explains that differences in chemical binding of the 210 Po as compared to those of other radionuclides (e.g., thorium-234) as the main factor. That suggests that differences in decay half-lives or physical factors are less important when these nuclides are applied to estimate the POC flux in the ocean.

Differences in immunity between pathogen-resistant and -susceptible yam cultivars reveal insights into disease prevention underlying ethylene supplementation - Shumei Hua; Zhihua Chen; Lihong Li; Kuan-Hung Lin; Yangwen Zhang; Jieyu Yang; Shi-Peng Chen (Journal of Plant Biochemistry and Biotechnology, 2021)

Luteolin alleviates ulcerative colitis through SHP-1/STAT3 pathway - Bo-Lin Li; Dan-Yang Zhao; Peng-Li Du; Xiao-Tian Wang; Qian Yang; Yan-Ru Cai (Inflammation Research, 2021)

Pomelo fruit wastes are potentially valuable antioxidants, anti-inflammatories, antihypertensives, and antihyperglycemics - Li-Yun Lin; Chi-Yun Huang; Kuan-Chou Chen; Robert Y. Peng (Horticulture, Environment, and Biotechnology, 2021)
Grapefruit (G) parts contain abundant phenolic acids and flavonoids (PPNs and FLVs). The wastes created from exocarps, mesocarps (G wastes, GW) and waste blanching water (WBW) lead to a considerable loss of PPNs and FLVs. Here, we assessed Buntan (CB), Buntan Hayata (CBH), and Peiyu (CP) cultivars and observed considerable amounts of PPNs and FLVs. The ethanolic extracts of GW (GWE) and WBW contained gallic acid, protocatechuic acid, chlorogenic acid, caffeic acid, ferulic acid, coumaric acid, naringin, hesperidin, diosmin, quercetin, hesperetin, nobiletin, and tangeretin (GWC). GWE has previously been reported to be a relatively active antioxidant, anti-inflammatory (based on the expression of TNF-α in Raw264.7 cells), antihypertensive, and anti-hyperglycemic compound. The IC 50 values for antihyperglycemic activity with WBW for α-amylase were as follows: CB (27.96 ± 0.03 mg/mL) < CP (28.13 ± 0.19 mg/mL) < CBH (41.60 ± 0.16 mg/mL), and those for α-glucosidase were CB (1.80 ± 0.03 mg/mL) < CP (2.97 ± 0.29 mg/mL) < CBH (9.10 ± 0.51 mg/mL). GWC upregulated Glut4 in HepG2 cells, as well as the insulin secretion capability, and intracellular levels in RIN-m5F cells, and it downregulated DPP4 in HepG2 cells. The IC 50 values for the angiotensin-converting enzyme activity were: CBP (5.10 ± 0.02 mg/mL) < CB (7.24 ± 0.65 mg/mL) < CP (8.60 ± 2.03 mg/mL). Our results indicate that PPNs and FLVs present in GW are worth reclaiming.

Performance of permeable pavement systems on stormwater permeability and pollutant removal - Zhiji Yu; Huihui Gan; Ming Xiao; Biao Huang; David Z. Zhu; Zheyun Zhang; Huanyan Wang; Yongliang Lin; Yonglong Hou; Shuai Peng; Wei Zhang (Environmental Science and Pollution Research, 2021)

The effects of dark treatment on photosynthesis and growth in young and mature leaves of Syzygium rehderianum - ZhengChao Yu; Wei Lin; XiaoTing Zheng; YanNa Luo; ChangLian Peng (Brazilian Journal of Botany, 2021)

A dye combination for the staining of pollen coat and pollen wall - Xin-Lei Jia; Jing-Shi Xue; Fang Zhang; Chi Yao; Shi-Yi Shen; Chang-Xu Sui; Yu-Jia Peng; Qin-Lin Xu; Yi-Feng Feng; Wen-Jing Hu; Ping Xu; Zhong-Nan Yang (Plant Reproduction, 2021)

Detection of Human Sapoviruses in Sewage in China by Next Generation Sequencing - Ke Song; Xiaojuan Lin; Yao Liu; Feng Ji; Li Zhang; Peng Chen; Chenxu Zhao; Yanyan Song; Zexin Tao; Aiqiang Xu (Food and Environmental Virology, 2021)

Cytotoxic meroterpenoids from the marine sponge Dactylospongia elegans - Hao-Bing Yu; Zi-Fei Yin; Bin-Bin Gu; Jian-Peng Zhang; Shu-Ping Wang; Fan Yang; Hou-Wen Lin (Natural Product Research, 2021)

PtP38 May Increase the Immune Ability of Portunus trituberculatus Stimulated by LPS Imitating a Gram-Negative Bacterial Infection - Cheng-Peng Lu; Chao-Guang Wei; Jun-Quan Zhu; Dao-Jun Tang; Chun-Lin Wang; Cong-Cong Hou (Frontiers in Marine Science, 2021)
The P38 mitogen-activated protein kinase (MAPK) signal transduction pathway is widespread in organisms and plays important roles in immune activities. The infection mechanism of environmental gram-negative bacteria on crustaceans is an important scientific problem. In this study, the cDNA full-length sequence of Portunus trituberculatus P38 (PtP38) was cloned and its structure was analyzed by bioinformatics methods. To study the function of the PtP38 gene after a Gram-negative bacterial infection, we injected P. trituberculatus with LPS to activate the immune response instead of directly infecting with Gram-negative bacteria. With LPS stimulation, the expression of the PtP38 gene in different tissues increased significantly. At the same time, the expression of immune-related genes (ALF and crustin) in the hepatopancreas, activities of antioxidant enzymes [superoxide dismutase (SOD), catalase (CAT), and inducible nitric oxide synthase (iNOS) enzymes], and expression of apoptosis-related genes (caspase2 and caspase3) were increased significantly. To further conform the function of PtP38 in the immune response, we injected P. trituberculatus with P38 inhibitor and subsequently injected with LPS. The results showed that the expression of immune-related genes was inhibited, the activity of antioxidant enzymes was decreased, and the expression of apoptosis-related genes were inhibited. Thus, we speculated that PtP38 may increase the immune ability by improving the expression of antimicrobial peptides, increasing the activity of oxidative stress-related enzymes, and promoting cell apoptosis in infected P. trituberculatus . This study also laid the foundation for further study of the P38 MAPK signaling pathway and immune mechanism of P. trituberculatus .

The resurgent landscape of xenotransplantation of pig organs in nonhuman primates - Xuan Zhang; Quancheng Wang; Jingjun Zhao; Xiao Li; Wei Peng; Zhaoxu Yang; Zhibin Lin; Long Yang; Rui Ding; Kaishan Tao; Kefeng Dou (Science China Life Sciences, 2021)

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

Construction of an infectious full-length cDNA clone of potato aucuba mosaic virus - Buyang Chen; Qi Lin; Yueyan Yin; Liangliang Jiang; Fang Wang; Shuzhen Hu; Xinyang Wu; Fei Xu; Jiejun Peng; Hongying Zheng; Chengqi Yan; Xiaohan Mo; et al. (Archives of Virology, 2021)

Cabbage defense response provoked by Trichoderma Th-LAAO - Chia-Min Liu; Shu-Ying Liu; Chuan-Kai Liao; Chaur-Tsuen Lo; Kuo-Chih Lin; Kou-Cheng Peng (Archives of Microbiology, 2021)

Physical interactions facilitate sex change in the protogynous orange‐spotted grouper, Epinephelus coioides - Jiaxing Chen; Cheng Peng; Jingjun Huang; Herong Shi; Ling Xiao; Lin Tang; Haoran Lin; Shuisheng Li; Yong Zhang (Journal of Fish Biology, 2021)
Sex change in teleost fishes is commonly regulated by social factors. In species that exhibit protogynous sex change, such as the orange‐spotted grouper Epinephelus coioides , when the dominant males are removed from the social group, the most dominant female initiates sex change. The aim of this study was to determine the regulatory mechanisms of socially controlled sex change in E. coioides . We investigated the seasonal variation in social behaviours and sex change throughout the reproductive cycle of E. coioides , and defined the behaviour pattern of this fish during the establishment of a dominance hierarchy. The social behaviours and sex change in this fish were affected by season, and only occurred during the prebreeding season and breeding season. Therefore, a series of sensory isolation experiments was conducted during the breeding season to determine the role of physical, visual and olfactory cues in mediating socially controlled sex change. The results demonstrated that physical interactions between individuals in the social groups were crucial for the initiation and completion of sex change, whereas visual and olfactory cues alone were insufficient in stimulating sex change in dominant females. In addition, we propose that the steroid hormones 11‐ketotestosterone and cortisol are involved in regulating the initiation of socially controlled sex change.

Phenolic constituents from the fresh pericarps of Juglans sigillata - Yi Lin; Jingjing Liang; Xiaogang Peng; Hanli Ruan (Natural Product Research, 2021)

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

Comparative understanding of metal hyperaccumulation in plants: a mini-review - Jia-Shi Peng; Yu-Hao Guan; Xian-Jing Lin; Xiao-Jing Xu; Lu Xiao; Hai-Hua Wang; Shuan Meng (Environmental Geochemistry and Health, 2021)

Carbon isotope variations of modern soils in the eastern margin of the Tibetan Plateau and their controlling factors - Lin Qi; Yan-song Qiao; Zong-xiu Liu; Sha-sha Peng; Yu Cheng; Yan Wang; Xu-jiao Zhang; Ming-zhong Tian; Shuai-bin Yang; Wen-bin Bai (Journal of Mountain Science, 2021)

Corrosion Mechanism of 5083 Aluminum Alloy in Seawater Containing Phosphate - Jiaming Wang; Haodong Yang; Min Du; Jian Hou; Wenshan Peng; Cunguo Lin (Journal of Ocean University of China, 2021)

Control System Design and Implementation at Flexible, Distributed Offshore Sensor Test Sites in the Yangtze Estuary Area - Qingsong Hu; Chao Jiang; Lin Du; Jun Li; Leilei Chen; Peng Xiang; Hongcheng Zhang; Hafiz Abd ur Rahman (Journal of Ocean University of China, 2021)

Assimilation of Radar and Cloud-to-Ground Lightning Data Using WRF-3DVar Combined with the Physical Initialization Method—A Case Study of a Mesoscale Convective System - Ruhui Gan; Yi Yang; Qian Xie; Erliang Lin; Ying Wang; Peng Liu (Journal of Meteorological Research, 2021)

GNSS-based hardware-in-the-loop simulations of spacecraft formation flying with the global ionospheric model TIEGCM - YuXiang Peng; Wayne A. Scales; Dong Lin (GPS Solutions, 2021)

Genome-Wide Identification of Copper Stress-Regulated and Novel MicroRNAs in Mulberry Leaf - Qiuxia Du; Peng Guo; Yisu Shi; Jian Zhang; Danyan Zheng; Yang Li; Adolf Acheampong; Ping Wu; Qiang Lin; Weiguo Zhao (Biochemical Genetics, 2021)

Alternation of soil bacterial and fungal communities by tomato–rice rotation in Hainan Island in Southeast of China - Xiang Ma; Minglun Du; Peng Liu; Yanqiong Tang; Hong Li; Qianhua Yuan; Yunze Ruan; Lei Meng; Jiachao Zhang; Min Lin; Zhu Liu (Archives of Microbiology, 2021)

Formation and driving factors of sulfate in PM2.5 at a high-level atmospheric SO2 city of Yangquan in China - Cheng Wang; Yulong Yan; Yueyuan Niu; Rumei Li; Yang Xu; Dongmei Hu; Jing Wu; Lin Peng (Air Quality, Atmosphere & Health, 2021)

Megafaunal Community Structure From the Abyssal to Hadal Zone in the Yap Trench - Dongsheng Zhang; Yadong Zhou; Jichao Yang; Thomas Linley; Ruiyan Zhang; Bo Lu; Peng Xu; Chengcheng Shen; Shiquan Lin; Yueyun Wang; Dong Sun; Xiaogu Wang; et al. (Frontiers in Marine Science, 2021)
Hadal trenches remain one of the unexplored ocean ecosystems due to the challenges of sampling at great depths. It is still unclear how a faunal community changes from the abyssal to the hadal zone, and which environmental variables are the key impacting factors. In this study, nine dives of the Human Occupied Vehicle (HOV) “ JIAOLONG ” were conducted from abyssal to hadal depths (4,435–6,796 m) in the Yap Trench on the southeastern boundary of the Philippine Sea Plate in the western Pacific, divided into 48,200 m video transects, to describe the megafaunal communities and reveal their relationship with environmental factors. A total of 1,171 megafauna organisms was recorded, 80 morphospecies (msps) from 8 phyla were identified based on the video data, most of which were reported for the first time in the Yap Trench. Arthropoda was the most abundant phylum and Echinodermata was the most diverse phylum of the megafaunal community. The faunal abundance increased with depth, whereas the Shannon diversity index decreased with depth. Cluster analysis suggested seven assemblages, with five abyssal groups, one mixed group, and one hadal dominant group. Although megafaunal communities changed gradually from abyssal zone to hadal zone, both PERMANOVA and PERMDISP analyses revealed that the communities are significantly different between abyssal zone and hadal zone, indicating 6,000 m as the boundary between the two depth zones. Depth, substrate, slope, and latitude were identified as four important environmental factors with significant influence on megafaunal community structure. This study proposed a transition pattern from the abyssal to hadal zone in the Yap Trench, highlighted the importance of habitat heterogeneity in structuring megafaunal community in a hadal trench.

Biopharmaceutics Applications of Physiologically Based Pharmacokinetic Absorption Modeling and Simulation in Regulatory Submissions to the U.S. Food and Drug Administration for New Drugs - Fang Wu; Heta Shah; Min Li; Peng Duan; Ping Zhao; Sandra Suarez; Kimberly Raines; Yang Zhao; Meng Wang; Ho-pi Lin; John Duan; Lawrence Yu; et al. (The AAPS Journal, 2021)

Spatial patterns of phytoplankton community and biomass along the Kuroshio Extension and adjacent waters in late spring - Yu Wang; Jianhua Kang; Xiuwu Sun; Jiang Huang; Yili Lin; Peng Xiang (Marine Biology, 2021)

Association of FMO3 rs1736557 polymorphism with clopidogrel response in Chinese patients with coronary artery disease - Kong-Xiang Zhu; Pei-Yuan Song; He-Li; Mu-Peng Li; Yin-xiao Du; Qi-lin Ma; Li-Ming Peng; Xiao-Ping Chen (European Journal of Clinical Pharmacology, 2021)

Transcriptome profiling reveals candidate genes associated with cold stress in mulberry - Acheampong Adolf; Li Liu; Michael Ackah; Yang Li; Qiuxia Du; Danyan Zheng; Peng Guo; Yisu Shi; Qiang Lin; Changyu Qiu; Weiguo Zhao (Brazilian Journal of Botany, 2021)

The bacterial composition associated with Atriolum robustum, a common ascidian from Xisha coral reef, China - Yong Liu; Peng Wu; Chunhou Li; Yayuan Xiao; Teng Wang; Lin Lin (Symbiosis, 2021)

Complete genome sequence of a novel foveavirus isolated from Allium sativum L. in China - Qi Luo; Shuzhen Hu; Qi Lin; Fei Xu; Jiejun Peng; Hongying Zheng; Guanwei Wu; Shaofei Rao; Jianping Chen; Yuwen Lu; Fengling Guo; Fei Yan (Archives of Virology, 2021)

Lentibacillus saliphilus. sp. nov., a moderately halophilic bacterium isolated from a saltern in Korea - Yun Wang; Gang-Qiang Jiang; Hong-Ping Lin; Peng Sun; Hong-Yan Zhang; Dong-Mei Lu; Li-Yun Wang; Chang-Jin Kim; Shu-Kun Tang (Archives of Microbiology, 2021)

Piriformospora indica colonization increases the growth, development, and herbivory resistance of sweet potato (Ipomoea batatas L.) - Qing Li; Yun-Wei Kuo; Kuan-Hung Lin; Weiqun Huang; Caisheng Deng; Kai-Wun Yeh; Shi-Peng Chen (Plant Cell Reports, 2021)

The novel three-dimensional pulse images analyzed by dynamic L-cube polynomial model - Ching-Hsing Luo; Zhan Zhang; Bo Peng; Xiaohua Xie; Tsung-Lin Lee; Liang-Miin Tsai (Medical & Biological Engineering & Computing, 2021)

Genome-Wide Association Study Identifies Genomic Loci of Sex Determination and Gonadosomatic Index Traits in Large Yellow Croaker (Larimichthys crocea) - Huanling Lin; Zhixiong Zhou; Ji Zhao; Tao Zhou; Huaqiang Bai; Qiaozhen Ke; Fei Pu; Weiqiang Zheng; Peng Xu (Marine Biotechnology, 2021)

First report of natural infection of tomato by pepper mild mottle virus in China - Wen Peng Zhou; Yue Yue Li; Fan Li; Guan Lin Tan (Journal of Plant Pathology, 2021)

Porous Cd0.5Zn0.5S nanocages derived from ZIF-8: boosted photocatalytic performances under LED-visible light - Lin Wu; Huifen Fu; Qi Wei; Qian Zhao; Peng Wang; Chong-Chen Wang (Environmental Science and Pollution Research, 2021)

Associations of Serum Selenium Levels in the First Trimester of Pregnancy with the Risk of Gestational Diabetes Mellitus and Preterm Birth: a Preliminary Cohort Study - Peng Ju Liu; Aimin Yao; Liangkun Ma; Xiao Yan Chen; Song Lin Yu; Yanping Liu; Yi Xuan Hou (Biological Trace Element Research, 2021)

Paleoglacial and paleoclimate reconstructions during the global Last Glacial Maximum in the Longriba area, eastern Tibetan Plateau - Wei-lin Yang; Ye-song Han; Xu Peng; Ze-ze Ran; Qing Liu; Geng-nian Liu (Journal of Mountain Science, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Triterpenoids from the fresh pericarps of Juglans hopeiensis - Yi Lin; Xiaogang Peng; Juan Chen; Jia Zhou; Hanli Ruan (Natural Product Research, 2021)

Preliminary study on relationships among nutritional risk, serum prealbumin, and peripheral blood T cell subsets in patients with severe COVID-19 - Yanli Li; Yanbo Sun; Jing He; Peng Zhao; Pengju Luo; Jinsong Bai; Weiming Li; Shumin Li; Yueying Lin; Yunyun Cen (Infectious Diseases, 2021)

Method for fast staining and obtaining high-magnification and high-resolution cell images of Nicotiana benthamiana - Yuanyuan Jiang; Jiangrong Peng; Yunpeng Cao; Zhiqiang Han; Ling Zhang; Wenbing Su; Shunquan Lin; Yuan Yuan; Bin Wang; Xianghui Yang; Zhike Zhang (Physiology and Molecular Biology of Plants, 2021)

Critical tension crack depth in rockslides that conform to the three-section mechanism - Guoqing Chen; Peng Tang; Runqiu Huang; Dong Wang; Zhiheng Lin; Da Huang (Landslides, 2021)

Improved control of Frankliniella occidentalis on greenhouse pepper through the integration of Orius sauteri and neonicotinoid insecticides - Qing-cai Lin; Hao Chen; Dirk Babendreier; Jin-ping Zhang; Feng Zhang; Xiao-yan Dai; Zuo-wen Sun; Zhao-peng Shi; Xiao-lin Dong; Guang-an Wu; Yi Yu; Li Zheng; et al. (Journal of Pest Science, 2021)

Low ambient temperature increases hospital re-admissions for systemic lupus erythematosus in humid subtropical region: a time series study - Qian Wu; Zhiwei Xu; Yi-Lin Dan; Peng Wang; Yan-Mei Mao; Chan-Na Zhao; Yan-Feng Zou; Dong-Qing Ye; Wenbiao Hu; Hai-Feng Pan (Environmental Science and Pollution Research, 2021)

Discrimination of Tourette Syndrome Based on the Spatial Patterns of the Resting–State EEG Network - Keyi Duan; Qian Wu; Yuanyuan Liao; Yajing Si; Joyce Chelangat Bore; Fali Li; Qin Tao; Li Lin; Wei Lei; Xudong Hu; Dezhong Yao; Changfu Pei; et al. (Brain Topography, 2021)

Complete genome sequence of a new achyranthes virus A isolate from Achyranthes bidentata in China - Xinyang Wu; Yuchao Lai; Lanqing Lv; Kelei Han; Ziqiang Chen; Yuwen Lu; Jiejun Peng; Lin Lin; Jianping Chen; Hongying Zheng; Fei Yan (Archives of Virology, 2021)

Impact of the March Arctic Oscillation on the South China Sea summer monsoon onset - Peng Hu; Wen Chen; Shangfeng Chen; Yuyun Liu; Lin Wang; Ruping Huang (International Journal of Climatology, 2021)
This study reveals that the South China Sea summer monsoon (SCSSM) onset is closely linked to the preceding March Arctic oscillation (AO), the dominant mode of atmospheric circulation over extratropical Northern Hemisphere. The physical processes for the impact of the March AO on the SCSSM onset are further examined. March AO leads to an anomalous low‐level cyclone over subtropical western North Pacific (WNP) via eddy–mean flow interaction. The southwesterly wind anomalies to the southeastern side of the anomalous cyclone weaken the climatological trade winds, which contribute to warm sea surface temperature (SST) anomalies over tropical western‐central North Pacific via reduction of surface evaporation and latent heat flux. These warm SST anomalies excite an atmospheric Rossby wave response and reinforce the anomalous cyclone over the subtropical WNP. Via the above positive atmosphere–ocean interaction, the anomalous cyclone induced by the March AO could persist through the whole spring and shift equatorward. This anomalous cyclone creates favourable environment for the SCSSM onset via weakening the WNP subtropical high and is conducive to the transition of the low‐level zonal wind. Further analysis indicates that the March AO‐SCSSM onset relationship is independent of El Niño‐Southern Oscillation (ENSO). This result suggests that, besides the dominant tropical system (i.e., ENSO), interannual variation of the SCSSM onset also has a close relation with the dominant extratropical atmospheric system (i.e., AO), which may provide additional source for the seasonal prediction of the monsoon onset.

Synthesis, characteristics and medical applications of plant nanomaterials - Lidong Du; Ruoyu Zhang; Hanchao Yang; Shaojian Tang; Zhaohua Hou; Jinjin Jing; Bingjie Lin; Shujie Zhang; Zhong Lu; Peng Xue (Planta, 2020)

High expression of NEK2 promotes lung cancer progression and drug resistance and is regulated by mutant EGFR - Chuanhui Chen; Shanshan Peng; Penghui Li; Lin Ma; Xin Gan (Molecular and Cellular Biochemistry, 2020)

Deep-Learning-Based Segmentation and Localization of White Matter Hyperintensities on Magnetic Resonance Images - Wenhao Jiang; Fengyu Lin; Jian Zhang; Taowei Zhan; Peng Cao; Silun Wang (Interdisciplinary Sciences: Computational Life Sciences, 2020)

Valine acts as a nutritional signal in brain to activate TORC1 and attenuate postprandial ammonia-N excretion in Chinese perch (Siniperca chuatsi) - Jie Wang; Xu-Fang Liang; Shan He; Yan-Peng Zhang; Jiao Li; Kang Huang; Lin-Jie Shi; Ping Ren (Fish Physiology and Biochemistry, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Prevalence and Bayesian Phylogenetics of Enteroviruses Derived From Environmental Surveillance Around Polio Vaccine Switch Period in Shandong Province, China - Chenxu Zhao; Xiaojuan Lin; Feng Ji; Ping Xiong; Yao Liu; Suting Wang; Peng Chen; Qing Xu; Li Zhang; Zexin Tao; Aiqiang Xu (Food and Environmental Virology, 2020)

Impact of the September Silk Road Pattern on the South China Sea summer monsoon withdrawal - Peng Hu; Wen Chen; Shangfeng Chen; Yuyun Liu; Lin Wang; Ruping Huang (International Journal of Climatology, 2020)
The Silk Road Pattern (SRP) is the dominant teleconnection in the upper troposphere and is closely linked to the Asian summer monsoon in both India and subtropical East Asia. This study reveals a close interannual relationship between the SRP in September and the South China Sea (SCS) summer monsoon (SCSSM) withdrawal. During positive phases of the September SRP (characterized by negative geopotential height anomalies over eastern Europe and central China and positive geopotential height anomalies over western Europe, western and central Asia, and Northeast Asia), withdrawal of the SCSSM tends to be later than normal. The September SRP could impact the SCSSM withdrawal via modulating atmospheric circulation anomalies over the SCS. In particular, the notable low‐level cyclonic anomaly over central China related to the positive phase of the September SRP induces significant southwesterly wind anomalies over the northern SCS, which favour a late withdrawal of the SCSSM. This study suggests that besides the tropical factors that have been identified by previous studies, the climate systems over mid‐latitudes may also play an important role in contributing to interannual variability of the SCSSM withdrawal.

MAPK pathway‐related tyrosine phosphatases regulate development, secondary metabolism and pathogenicity in fungus Aspergillus flavus - Guang Yang; Xiaohong Cao; Genli Ma; Ling Qin; Yuanzhen Wu; Jian Lin; Peng Ye; Jun Yuan; Shihua Wang (Environmental Microbiology, 2020)
Summary Mitogen‐activated protein kinase (MAPK) cascades are highly conserved in eukaryotic cells and are known to play crucial roles in the regulation of various cellular processes. However, compared with kinase‐mediated phosphorylation, dephosphorylation catalysed by phosphatases has not been well characterized in filamentous fungi. In this study, we identified five MAPK pathway‐related phosphatases (Msg5, Yvh1, Ptp1, Ptp2 and Oca2) and characterized their functions in Aspergillus flavus , which produces aflatoxin B 1 (AFB 1 ), one of the most toxic and carcinogenic secondary metabolites. These five phosphatases were identified as negative regulators of MAPK (Slt2, Fus3 and Hog1) pathways. Deletion of Msg5 and Yvh1 resulted in significant defects in conidiation, sclerotia formation, aflatoxin production and crop infection. Additionally, double knockout mutants (Δ Msg5/ Δ Ptp1 , Δ Msg5/ Δ Ptp2 and Δ Msg5/ Δ Oca2 ) displayed similar defects to those observed in the Δ Msg5 single mutant, indicating that Msg5 plays a major role in the regulation of development and pathogenicity in A . flavus . Importantly, we found that the active site at C439 is essential for the function of the Msg5 phosphatase. Furthermore, the MAP kinase Fus3 was found to be involved in the regulation of development, aflatoxin biosynthesis and pathogenicity, and its conserved phosphorylation residues (Thr and Tyr) were critical for the full range of its functions in A . flavus . Overall, our results reveal that MAPK related tyrosine phosphatases play important roles in the regulation of development, secondary metabolism and pathogenicity in A . flavus , and could be developed as potential targets for preventing damage caused by this fungal pathogen.

Incorporation of Hydroxamate Siderophore and Associated Fe Into Marine Particles in Natural Seawater - Peng Lin; Chen Xu; Luni Sun; Wei Xing; Peter H. Santschi (Frontiers in Marine Science, 2020)

FW0622, a new siderophore isolated from marine Verrucosispora sp. by genomic mining - Wei Zhao; Fei Peng; Chuan-xi Wang; Yang Xie; Ru Lin; Zhi-kai Fang; Fei Sun; Yun-yang Lian; Hong Jiang (Natural Product Research, 2020)

First report of natural infection of tomato yellow leaf curl virus on cucumber in China - Feng Zhu; Qin-Qin Zhang; Peng-Xiang Zhu; Qi-Ping Zhang; Meng-Yao Cao; Zhao-Lin Ji (Journal of Plant Pathology, 2020)

First report of tobacco mosaic virus infecting Lagenaria siceraria (Molina) Standl. var. clavata Makino in China - Peng-Xiang Zhu; Qi-Ping Zhang; Zhao-Lin Ji; Feng Zhu (Journal of Plant Pathology, 2020)

A Novel Sediment Pressure Sampling Device Carried by a Hadal-Rated Lander - Jiawang Chen; Yue Huang; Yuan Lin; Peng Zhou; Yuping Fang; Xiaoling Le; Yuhong Wang (Journal of Marine Science and Engineering, 2020)
Reliable sampling technology for deep-sea sediments is a prerequisite for studying the sedimentary environment in the geological history, the mechanical characteristics of sediments and sediment biology. In this study, we develop a new sampling device in order to achieve a convenient and economic pressure sampling for hadal sediments. The overall structure, as well as the key component such as the pressure-holding part, and the sealing structure are designed. The feasibility of the device was verified through field tests. Furthermore, the sampling process is analyzed by the computer simulation. It is found that the sampling length is determined by the open diameter and the installation position of the core keepers. According to the simulation, the structure is optimized, which is beneficial to the further improvement of the sampling length.

Mitigating Climate Change for Sugarcane Improvement: Role of Silicon in Alleviating Abiotic Stresses - Krishan K. Verma; Pratiksha Singh; Xiu-Peng Song; Mukesh Kumar Malviya; Rajesh Kumar Singh; Gan-Lin Chen; Sushil Solomon; Yang-Rui Li (Sugar Tech, 2020)

Genome-Wide Association Study of Body Shape-Related Traits in Large Yellow Croaker (Larimichthys crocea) - Shengnan Kong; Zhixiong Zhou; Tao Zhou; Ji Zhao; Lin Chen; Huanling Lin; Fei Pu; Qiaozhen Ke; Huaqiang Bai; Peng Xu (Marine Biotechnology, 2020)

Local Softening Characteristic of Soft Clay Subjected to Dynamic Loading Under Low Confining Pressure - Peng Lin; Shanbo Jiao; Ankit Garg; Suriya Ganesan; Jitendra Singh Yadav (Geotechnical and Geological Engineering, 2020)

Stable isotopes reveal effects of natural drivers and anthropogenic pressures on isotopic niches of invertebrate communities in a large subtropical river of China - Sai Wang; Lin-Hui Su; Bang-Ke Luo; Ying-Jun Qin; Simon D. Stewart; Jin-Peng Tang; Tuan-Tuan Wang; Yang Yang; Gong Cheng (Environmental Science and Pollution Research, 2020)

Sodium Para-aminosalicylic Acid Reverses Changes of Glutamate Turnover in Manganese-Exposed Rats - Zhao-Cong Li; Fang Wang; Shao-Jun Li; Lin Zhao; Jun-Yan Li; Yue Deng; Xiao-Juan Zhu; Yu-Wen Zhang; Dong-Jie Peng; Yue-Ming Jiang (Biological Trace Element Research, 2020)

Carbon emission efficiency of thermal power in different regions of China and spatial correlations - Jin Zhu; Huaping Sun; Dequn Zhou; Lin Peng; Chuanwang Sun (Mitigation and Adaptation Strategies for Global Change, 2020)

Silencing of LRP1 Exacerbates Inflammatory Response Via TLR4/NF-κB/MAPKs Signaling Pathways in APP/PS1 Transgenic Mice - Yingying He; John Bosco Ruganzu; Quzhao Zheng; Xiangyuan Wu; Hui Jin; Xiaoqian Peng; Bo Ding; Chengheng Lin; Shengfeng Ji; Yanbing Ma; Weina Yang (Molecular Neurobiology, 2020)

Colletotrichum neorubicola sp. nov., a new leaf anthracnose pathogen of raspberry from northeast China - Li-Ping Liu; Yu Wang; Peng-Lei Qiu; Bo Zhang; Lin Zhang; Na Wang; Yu Li; Jie Gao; Tom Hsiang (Mycological Progress, 2020)

Immune effect of a Newcastle disease virus DNA vaccine with IL-12 as a molecular adjuvant delivered by electroporation - Peng Xie; Yanling Li; Yaling Li; Jianpeng Liang; Bin Xiang; Qiuyan Lin; Jiaqi Jin; Chan Ding; Chenggang Xu; Tao Ren (Archives of Virology, 2020)

Natural sex change in mature protogynous orange‐spotted grouper ( Epinephelus coioides ): gonadal restructuring, sex hormone shifts and gene profiles - Cheng Peng; Qing Wang; Herong Shi; Jiaxing Chen; Shuisheng Li; Huihong Zhao; Haoran Lin; Jianchun Yang; Yong Zhang (Journal of Fish Biology, 2020)
Sexual patterns of teleosts are extremely diverse and include both gonochorism and hermaphroditism. As a protogynous hermaphroditic fish, all orange‐spotted groupers ( Epinephelus coioides ) develop directly into females, and some individuals change sex to become functional males later in life. This study investigated gonadal restructuring, shifts in sex hormone levels and gene profiles of cultured mature female groupers during the first (main) breeding season of 2019 in Huizhou, China (22° 42′ 02.6″ N, 114° 32′ 10.1″ E). Analysis of gonadal restructuring revealed that females with pre‐vitellogenic ovaries underwent vitellogenesis, spawning and regression and then returned to the pre‐vitellogenic stage in the late breeding season, at which point some changed sex to become males via the intersex gonad stage. A significant decrease in the level of serum 17 β ‐estradiol (E2) was observed during ovary regression but not during sex change, whereas serum 11‐ketotestosterone (11‐KT) concentrations increased significantly during sex change with the highest concentration in newly developed males. Consistent with serum hormone changes, a significant decrease in cyp19a1a expression was observed during ovary regression but not during sex change, whereas the expression of cyp11c1 and hsd11b2 increased significantly during sex change. Interestingly, hsd11b2 but not cyp11c1 was significantly upregulated from the pre‐vitellogenic ovary stage to the early intersex gonad stage. These results suggest that a decrease in serum E2 concentration and downregulation of cyp19a1a expression are not necessary to trigger the female‐to‐male transformation, whereas increased 11‐KT concentration and upregulation of hsd11b2 expression may be key events for the initiation of sex change in the orange‐spotted grouper.

Five new ent -kaurane diterpenes from Annona squamosa L. pericarps - Ya-Yun Chen; Cheng-Yao Ma; Mao-Lin Wang; Jia-Hui Lu; Peng Hu; Jian-Wei Chen; Xiang Li; Yong Chen (Natural Product Research, 2020)

The impact of secondary inorganic aerosol emissions change on surface air temperature in the Northern Hemisphere - Chunjiang Zhou; Peng Liu; Gang Huang; Jintai Lin; Kaiming Hu; Lulu Chen; Jingxu Wang; Sixuan Li; Su Wang; Ruijing Ni (Theoretical and Applied Climatology, 2020)

Synergistic effects of pazopanib and hyperthermia against uterine leiomyosarcoma growth mediated by downregulation of histone acetyltransferase 1 - Chiao-Yun Lin; Angel Chao; Ren-Chin Wu; Li-Yu Lee; Shir-Hwa Ueng; Chia-Lung Tsai; Yun-Shien Lee; Meng-Ting Peng; Lan-Yan Yang; Huei-Jean Huang; Hsin-Shih Wang; Chyong-Huey Lai (Journal of Molecular Medicine, 2020)

Two novel pleiotropic loci associated with osteoporosis and abdominal obesity - Lu Liu; Xiao-Lin Yang; Hong Zhang; Zi-Jia Zhang; Xin-Tong Wei; Gui-Juan Feng; Ju Liu; Hui-Ping Peng; Rong Hai; Hui Shen; Qing Tian; Hong-Wen Deng; et al. (Human Genetics, 2020)

Cinnamaldehyde improves the growth performance and digestion and absorption capacity in grass carp (Ctenopharyngodon idella) - Yang Zhou; Wei-Dan Jiang; Jin-Xiu Zhang; Lin Feng; Pei Wu; Yang Liu; Jun Jiang; Sheng-Yao Kuang; Ling Tang; Yan Peng; Xiao-Qiu Zhou (Fish Physiology and Biochemistry, 2020)

Enhancement of the activity of Cu/TiO2 catalyst by Eu modification for selective catalytic reduction of NOx with NH3 - Yuan-zhen Liu; Qi-yan Xu; Rui-tang Guo; Chao-peng Duan; Gui-lin Wu; Yu-fang Miao; Jing-wen Gu (Environmental Science and Pollution Research, 2020)

Bias Adjustment of Satellite Precipitation Estimation Using Ground-Based Observation: Mei-Yu Front Case Studies in Taiwan - Nan-Ching Yeh; Yao-Chung Chuang; Hsin-Shuo Peng; Kuo-Lin Hsu (Asia-Pacific Journal of Atmospheric Sciences, 2020)
The Global Satellite Mapping of Precipitation (GSMaP) was used to estimate the accumulated rainfall in May from the Mei-Yu front in Taiwan. Rainfall estimation from GSMaP during 2002–2017 were evaluated using more than 400 local gauge observations, collected from the Taiwan Central Weather Bureau (CWB). Studies have demonstrated that the GSMaP rainfall estimation estimates can be biased, depending on the target region, elevation, and season. In this experiment, we have evaluated GSMaP over three elevation ranges. The GSMaP systemic errors for each elevation range were identified and corrected using regression analysis. The results indicated that GSMaP estimation can be improved significantly through adjustment over three elevation ranges (elevation less than 50 m, elevation of 50–100 m, and elevation higher than 100 m). For these three elevation ranges, the correlation coefficient between the GSMaP estimations and CWB rainfall data was 0.76, 0.78, and 0.59, respectively. This indicated that the GSMaP estimation was more accurate for low-elevation regions than high-elevation regions. After the proposed approaches were employed to correct the errors, the bias errors were respectively improved by 5.64(13.7%), 7.33(38.4%) and 10.52(31.2%) mm for low-, mid- and high-elevation regions. This study demonstrated that the local correction approaches can be used to improve GSMaP estimation of Mei-Yu rainfall in Taiwan.

Experimental investigation for dynamic instability of coal-rock masses in horizontal section mining of steeply inclined coal seams - Zheng-yi Wang; Lin-ming Dou; Jiang He; An-ye Cao; Xiong-wei Li; Peng-bo Li; Chang-sheng Wu (Arabian Journal of Geosciences, 2020)

Characteristics and health risk assessments of heavy metals in PM2.5 in Taiyuan and Yuci college town, China - Xiaofeng Liu; Zhilei Wang; Huiling Bai; Shuting Zhang; Ling Mu; Lin Peng (Air Quality, Atmosphere & Health, 2020)

Critical transition of soil bacterial diversity and composition triggered by nitrogen enrichment - Weixing Liu; Lin Jiang; Sen Yang; Zhou Wang; Rui Tian; Ziyang Peng; Yongliang Chen; Xingxu Zhang; Jialiang Kuang; Ning Ling; Shaopeng Wang; Lingli Liu (Ecology, 2020)
Soil bacterial communities are pivotal in regulating terrestrial biogeochemical cycles and ecosystem functions. The increase in global nitrogen (N) deposition has impacted various aspects of terrestrial ecosystems, but we still have a rudimentary understanding of whether there is a threshold for N input level beyond which soil bacterial communities will experience critical transitions. Using high‐throughput sequencing of the 16S rRNA gene, we examined soil bacterial responses to a long‐term (13 yr), multi‐level, N addition experiment in a temperate steppe of northern China. We found that plant diversity decreased in a linear fashion with increasing N addition. However, bacterial diversity responded nonlinearly to N addition, such that it was unaffected by N input below 16 g N·m −2 ·yr −1 , but decreased substantially when N input exceeded 32 g N·m −2 ·yr −1 . A meta‐analysis across four N addition experiments in the same study region further confirmed this nonlinear response of bacterial diversity to N inputs. Substantial changes in soil bacterial community structure also occurred between N input levels of 16 to 32 g N·m −2 ·yr −1 . Further analysis revealed that the loss of soil bacterial diversity was primarily attributed to the reduction in soil pH, whereas changes in soil bacterial community were driven by the combination of increased N availability, reduced soil pH, and changes in plant community structure. In addition, we found that N addition shifted bacterial communities toward more putatively copiotrophic taxa. Overall, our study identified a threshold of N input level for bacterial diversity and community composition. The nonlinear response of bacterial diversity to N input observed in our study indicates that although bacterial communities are resistant to low levels of N input, further increase in N input could trigger a critical transition, shifting bacterial communities to a low‐diversity state.

Improving the Computational Efficiency for Optimization of Offshore Wind Turbine Jacket Substructure by Hybrid Algorithms - Ding-Peng Liu; Tsung-Yueh Lin; Hsin-Haou Huang (Journal of Marine Science and Engineering, 2020)
When solving real-world problems with complex simulations, utilizing stochastic algorithms integrated with a simulation model appears inefficient. In this study, we compare several hybrid algorithms for optimizing an offshore jacket substructure (JSS). Moreover, we propose a novel hybrid algorithm called the divisional model genetic algorithm (DMGA) to improve efficiency. By adding different methods, namely particle swarm optimization (PSO), pattern search (PS) and targeted mutation (TM) in three subpopulations to become “divisions,” each division has unique functionalities. With the collaboration of these three divisions, this method is considerably more efficient in solving multiple benchmark problems compared with other hybrid algorithms. These results reveal the superiority of DMGA in solving structural optimization problems.

Three new phenylacetamide glycosides from Dracocephalum tanguticum Maxim and their anti-hyperglycemic activity - En-Guang Ma; Hai-Yan Wu; Li-Jiao Hu; Min Wei; Lin-Yun Mou; Gan-Peng Li (Natural Product Research, 2020)

Epidemiological and genetic characteristics of porcine reproduction and respiratory syndrome virus 2 in mainland China, 2017–2018 - Sisi Xie; Wan Liang; Xueying Wang; Hongjian Chen; Jie Fan; Wenbo Song; Lin Hua; Xibiao Tang; Huanchun Chen; Zhong Peng; Bin Wu (Archives of Virology, 2020)

Contamination characteristics of heavy metals in particle size fractions from street dust from an industrial city, Central China - Ping Zhong; Jia-Quan Zhang; Da-Mao Xu; Qian Tian; Tian-Peng Hu; Xiang-Yi Gong; Chang-Lin Zhan; Shan Liu; Xin-Li Xing; Shi-Hua Qi (Air Quality, Atmosphere & Health, 2020)

GPI7‐mediated glycosylphosphatidylinositol anchoring regulates appressorial penetration and immune evasion during infection of Magnaporthe oryzae - Caiyun Liu; Junjie Xing; Xuan Cai; Ahmed Hendy; Wenhui He; Jun Yang; Junbing Huang; You‐Liang Peng; Lauren Ryder; Xiao‐Lin Chen (Environmental Microbiology, 2020)
Summary Glycosylphosphatidylinositol (GPI) anchoring plays key roles in many biological processes by targeting proteins to the cell wall; however, its roles are largely unknown in plant pathogenic fungi. Here, we reveal the roles of the GPI anchoring in Magnaporthe oryzae during plant infection. The GPI‐anchored proteins were found to highly accumulate in appressoria and invasive hyphae. Disruption of GPI7 , a GPI anchor‐pathway gene, led to a significant reduction in virulence. The Δ gpi7 mutant showed significant defects in penetration and invasive growth. This mutant also displayed defects of the cell wall architecture, suggesting GPI7 is required for cell wall biogenesis. Removal of GPI‐anchored proteins in the wild‐type strain by hydrofluoric acid (HF) pyridine treatment exposed both the chitin and β‐1,3‐glucans to the host immune system. Exposure of the chitin and β‐1,3‐glucans was also observed in the Δ gpi7 mutant, indicating GPI‐anchored proteins are required for immune evasion. The GPI anchoring can regulate subcellular localization of the Gel proteins in the cell wall for appressorial penetration and abundance of which for invasive growth. Our results indicate the GPI anchoring facilitates the penetration of M. oryzae into host cells by affecting the cell wall integrity and the evasion of host immune recognition.

Outflow sediment concentration forecasting by integrating machine learning approaches and time series analysis in reservoir desilting operation - Ming-Jui Chang; Gwo-Fong Lin; Fong-Zuo Lee; Yi-Cheng Wang; Peng-An Chen; Ming-Chang Wu; Jihn-Sung Lai (Stochastic Environmental Research and Risk Assessment, 2020)

Selective catalytic reduction of NOx by NH3 over CeVO4-CeO2 nanocomposite - Chao-peng Duan; Rui-tang Guo; Gui-lin Wu; Wei-guo Pan (Environmental Science and Pollution Research, 2020)

Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China - Cheng-yi Lin; Die Li; Jie-ming Lu; Zhe-bin Yu; Yao Zhu; Peng Shen; Meng-ling Tang; Ming-juan Jin; Hong-bo Lin; Li-ming Shui; Kun Chen; Jian-bing Wang (Environmental Science and Pollution Research, 2020)

The maize B chromosome is capable of expressing microRNAs and altering the expression of microRNAs derived from A chromosomes - Yen-Hua Huang; Shu-Fen Peng; Yao-Pin Lin; Ya-Ming Cheng (Chromosome Research, 2020)

Hypertrophic olivary degeneration: a single case report - Wei Jiang; Xiao-Zhong Jing; Lin Gan; Ming Dong; Peng Yu (Acta Neurologica Belgica, 2020)

Plastic pollution in croplands threatens long‐term food security - Dan Zhang; Ee Ling Ng; Wanli Hu; Hongyuan Wang; Pablo Galaviz; Hude Yang; Wentao Sun; Chongxiao Li; Xingwang Ma; Bin Fu; Peiyi Zhao; Fulin Zhang; et al. (Global Change Biology, 2020)
Plastic pollution is a global concern given its prevalence in aquatic and terrestrial ecosystems. Studies have been conducted on the distribution and impact of plastic pollution in marine ecosystems, but little is known on terrestrial ecosystems. Plastic mulch has been widely used to increase crop yields worldwide, yet the impact of plastic residues in cropland soils to soil health and crop production in the long term remained unclear. In this paper, using a global meta‐analysis, we found that the use of plastic mulch can indeed increase crop yields on average by 25%–42% in the immediate season due to the increase of soil temperature (+8%) and moisture (+17%). However, the unabated accumulation of film residues in the field negatively impacts its physicochemical properties linked to healthy soil and threatens food production in the long term. It has multiple negative impacts on plant growth including crop yield (at the mean rate of −3% for every additional 100 kg/ha of film residue), plant height (−2%) and root weight (−5%), and soil properties including soil water evaporation capacity (−2%), soil water infiltration rate (−8%), soil organic matter (−0.8%) and soil available phosphorus (−5%) based on meta‐regression. Using a nationwide field survey of China, the largest user of plastic mulch worldwide, we found that plastic residue accumulation in cropland soils has reached 550,800 tonnes, with an estimated 6%–10% reduction in cotton yield in some polluted sites based on current level of plastic residue content. Immediate actions should be taken to ensure the recovery of plastic film mulch and limit further increase in film residue loading to maintain the sustainability of these croplands.

Two new xanthone glycosides from Swertia punicea Hemsl. and their anti-inflammatory activity - Lin-Yun Mou; Hai-Yan Wu; En-Guang Ma; Ming-Feng Wang; Yan-Qing Duan; Sheng Lei; Gan-Peng Li (Natural Product Research, 2020)

Anti-phytopathogenic Bacterial Metabolites From the Seaweed-Derived Fungus Aspergillus sp. D40 - Rui-Huan Huang; Wei Lin; Peng Zhang; Jian-Yang Liu; Dan Wang; Yi-Qiang Li; Xiao-Qiang Wang; Cheng-Sheng Zhang; Wei Li; Dong-Lin Zhao (Frontiers in Marine Science, 2020)

Two new aromatic polyketides from a deep-sea fungus Penicillium sp. SCSIO 06720 - Cui Guo; Xiu-Ping Lin; Sheng-Rong Liao; Bin Yang; Xue-Feng Zhou; Xian-Wen Yang; Xin-Peng Tian; Jun-Feng Wang; Yong-Hong Liu (Natural Product Research, 2020)

An overview of COVID-19 - Yu Shi; Gang Wang; Xiao-peng Cai; Jing-wen Deng; Lin Zheng; Hai-hong Zhu; Min Zheng; Bo Yang; Zhi Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Acceleration of thaw slump during 1997–2017 in the Qilian Mountains of the northern Qinghai-Tibetan plateau - Cuicui Mu; Jianguo Shang; Tingjun Zhang; Chengyan Fan; Shufa Wang; Xiaoqing Peng; Wen Zhong; Feng Zhang; Mei Mu; Lin Jia (Landslides, 2020)

Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients - Huan-Yu Meng; Xi Li; Wan-Lin Jin; Cheng-Kai Yan; Xiao-Hua Dong; Qiu Xu; Yu-Yao Peng; Zhi-Bin Li; Yi Li; Zhao-Hui Luo; Li-Qun Xu; Huan Yang (European Journal of Clinical Pharmacology, 2020)

Construction expression and immunogenicity of a novel trivalent outer membrane protein (OmpU‐A‐II) from three bacterial pathogens in Japanese eels ( Anguilla japonica ) - Jinping Zhao; Liqun Wu; Shaowei Zhai; Peng Lin; Songlin Guo (Journal of Fish Diseases, 2020)
Vibrio vulnificus , Edwardsiella anguillarum and Aeromonas hydrophila are three common bacterial pathogens in cultivated eels. To protect farming eels from infection by these pathogens, a trivalent outer membrane protein (OMP) containing partial sequences of OmpU from V. vulnificus , OmpA from E. anguillarum and OmpII from A. hydrophila was expressed and purified; then, the OMP was used as a vaccine to immunize Japanese eels ( Anguilla japonica ). Whole‐blood cell proliferation, antibody titres and complement and lysozyme activities were detected at different days post‐immunization (dpi), and the relative per cent survival (RPS) was determined after eels were infected with V. vulnificus , E. anguillarum or A. hydrophila at 28 dpi. The results showed that the OMP significantly stimulates the antibody titres. At 14 days after the challenge (i.e. at 28 dpi), the RPS of OMP against V. vulnificus, E. anguillarum and A. hydrophila was 20%, 70% and 11.1%, respectively. The construction, expression and immunogenicity of a trivalent Omp were reported for the first time, and this study will provide a valuable reference for the development of fish multiplex vaccines.

Opportunistic bacteria use quorum sensing to disturb coral symbiotic communities and mediate the occurrence of coral bleaching - Jin Zhou; Zi‐Jun Lin; Zhong‐Hua Cai; Yan‐Hua Zeng; Jian‐Ming Zhu; Xiao‐Peng Du (Environmental Microbiology, 2020)
Summary Coral associated microorganisms, especially some opportunistic pathogens can utilize quorum‐sensing (QS) signals to affect population structure and host health. However, direct evidence about the link between coral bleaching and dysbiotic microbiomes under QS regulation was lacking. Here, using 11 opportunistic bacteria and their QS products (AHLs, acyl‐homoserine‐lactones), we exposed Pocillopora damicornis to three different treatments: test groups (A and B: mixture of AHLs‐producing bacteria and cocktail of AHLs signals respectively); control groups (C and D: group A and B with furanone added respectively); and a blank control (group E: only seawater) for 21 days. The results showed that remarkable bleaching phenomenon was observed in groups A and B. The operational taxonomic units‐sequencing analysis shown that the bacterial network interactions and communities composition were significantly changed, becoming especially enhanced in the relative abundances of Vibrio , Edwardsiella , Enterobacter , Pseudomonas , and Aeromonas . Interestingly, the control groups (C and D) were found to have a limited influence upon host microbial composition and reduced bleaching susceptibility of P. damicornis . These results indicate bleaching's initiation and progression may be caused by opportunistic bacteria of resident microbes in a process under regulation by AHLs. These findings add a new dimension to our understanding of the complexity of bleaching mechanisms from a chemoecological perspective.

Nanochemoprevention with therapeutic benefits: An updated review focused on epigallocatechin gallate delivery - Qiong-Qiong Yang; Xin-Lin Wei; Ya-Peng Fang; Ren-You Gan; Min Wang; Ying-Ying Ge; Dan Zhang; Li-Zeng Cheng; Harold Corke (Critical Reviews in Food Science and Nutrition, 2020)

Development of a real-time forecasting model for turbidity current arrival time to improve reservoir desilting operation - Ming-Jui Chang; Gwo-Fong Lin; Peng-An Chen; Fong-Zuo Lee; Jihn-Sung Lai (Hydrological Sciences Journal, 2020)

Epitranscriptomic technologies and analyses - Xiaoyu Li; Qiao-Xia Liang; Jin-Ran Lin; Jinying Peng; Jian-Hua Yang; Chengqi Yi; Yang Yu; Qiangfeng Cliff Zhang; Ke-Ren Zhou (Science China Life Sciences, 2020)

The Cannabinoid Receptor Agonist WIN55,212-2 Ameliorates Hippocampal Neuronal Damage After Chronic Cerebral Hypoperfusion Possibly Through Inhibiting Oxidative Stress and ASK1-p38 Signaling - Da-Peng Wang; Qiao-Li Lv; Qi Lin; Kai Kang; Kai-Yan Jin; Jian Hai (Neurotoxicity Research, 2020)

Comparative transcriptomic analysis of vascular endothelial cells after hypoxia/re-oxygenation induction based on microarray technology - Jia Xu; Jiu-kun Jiang; Xiao-lin Li; Xiao-peng Yu; Ying-ge Xu; Yuan-qiang Lu (Journal of Zhejiang University-SCIENCE B, 2020)

Mechanisms behind soil N dynamics following cover restoration in degraded land in subtropical China - Xiangzhou Zheng; Cheng Lin; Baoling Guo; Juhua Yu; Hong Ding; Shaoyun Peng; Jinbo Zhang; Eric Ireland; Deli Chen; Christoph Müller; Yushu Zhang (Journal of Soils and Sediments, 2020)

Endometrial autophagy is essential for embryo implantation during early pregnancy - Yan Su; Juan-Juan Zhang; Jun-Lin He; Xue-Qing Liu; Xue-Mei Chen; Yu-Bin Ding; Chao Tong; Chuan Peng; Yan-Qing Geng; Ying-Xiong Wang; Ru-Fei Gao (Journal of Molecular Medicine, 2020)

Preparation of Novel ALRCs/nZVI Composite and Its Removal of Cr(VI) from Aqueous - Xuan Zhang; Xiao-qiang Cao; Guang Li; Jijie Yin; Di Zhang; Mingzhen Li; Na Meng; Liang Dong; Xian-jun Lyu; Lin Li; Jun Qiu; Yan Zhang; et al. (International Journal of Environmental Research, 2020)

Effects of small nucleolar RNA SNORD44 on the proliferation, apoptosis and invasion of glioma cells - Xian-Ru Xia; Wen-Cui Li; Zong-Tao Yu; Jie Li; Chun-Yan Peng; Li Jin; Guo-Lin Yuan (Histochemistry and Cell Biology, 2020)

ANN Model Development for Air Permeability in Biochar Amended Unsaturated Soil - Weiling Cai; Himanshu Kumar; Shan Huang; Sanandam Bordoloi; Ankit Garg; Peng Lin; Phani Gopal (Geotechnical and Geological Engineering, 2020)

A new DRP-4DVar-based coupled data assimilation system for decadal predictions using a fast online localization technique - Yujun He; Bin Wang; Wenyu Huang; Shiming Xu; Yong Wang; Li Liu; Lijuan Li; Juanjuan Liu; Yongqiang Yu; Yanluan Lin; Xiaomeng Huang; Yiran Peng (Climate Dynamics, 2020)

Viral metagenomics reveals sapoviruses of different genogroups in stool samples from children with acute gastroenteritis in Jiangsu, China - Wang Li; Surong Dong; Juan Xu; Xiaobin Zhou; Junling Han; Zhaqing Xie; Qin Gong; Hailin Peng; Chenglin Zhou; Mei Lin (Archives of Virology, 2020)
Sapoviruses (SAVs), including several genogroups (GI to GV), are one of the causes of acute gastroenteritis (AGE). In this study, viral metagenomics revealed the presence of sapoviruses of different genogroups in stool from children with AGE. Eight different complete SAV genomes were determined, of which five belonged to GI and the other three belonged to GII, GIV and GV, respectively. Although they were highly similar to published sequences, the GIV and GV were the first complete genome sequences of these SAVs found in China. In a prevalence investigation, 19% of subjects with AGE were positive for SAVs, while none of the control group was positive.

Spatial Distribution and Formation Mechanism of Water-soluble Inorganic Ions in PM2.5 During a Typical Winter Haze Episode in Guilin, China - Tengfa Long; Bin Peng; Zhihui Yang; Cynthia Sabrine Ishimwe; Chongjian Tang; Ning Zhao; Hong Lin; Kai Zhong; Shan Zhong (Archives of Environmental Contamination and Toxicology, 2020)

A new pelagic Polyconchoecia Xiang, Chen and Du, 2018 (Ostracoda: Myodocopa: Halocyprididae) from the South China Sea - Peng Xiang; Yu Wang; Ruixiang Chen; Youyin Ye; Chunguang Wang; Xiaoyin Chen; Mao Lin (Acta Oceanologica Sinica, 2020)

Abundance and residency dynamics of the Indo‐Pacific humpback dolphin, Sousa chinensis , in the Dafengjiang River Estuary, China - Chongwei Peng; Haiping Wu; Xianyan Wang; Qian Zhu; Thomas A. Jefferson; Chun‐Chieh Wang; Youhou Xu; Jian Li; Hu Huang; Mo Chen; Shiang‐Lin Huang (Marine Mammal Science, 2020)
Robust population size estimates are essential for informing population conservation status. Residency dynamics show population habitat use through time. Population size of Indo‐Pacific humpback dolphins ( Sousa chinensis ) has been extensively investigated in Chinese waters, but their residency dynamics are rarely known. Mark‐recapture analysis based on photo‐identification records was applied to humpback dolphins in the Dafengjiang River Estuary habitat, one of the key habitats in the northern Beibu Gulf, China. Movement analyses based on lagged identification rate indicated the humpback dolphins spent, on average, 78.5 days inside and 46.9 days outside the survey area. Within the study area, the humpback dolphin abundance was 83 identifiable dolphins. A total of 353–430 humpback dolphins, estimated by POPAN modeling, were involved in this fluid habitat‐use dynamic. Robust Design analysis showed strong seasonality in humpback dolphin abundance and emigration probability, implying a movement‐ and habitat‐use pattern likely associated with spatiotemporal distribution of oceanographic characteristics and prey occurrences. Population surveys and conservation measures currently conducted in Chinese waters seldom consider seasonality in movements between habitat patches, which can be addressed by genetic analyses across habitats and cross‐matching photo‐identification records among neighboring habitats.

Mechanisms of soil bacterial and fungal community assembly differ among and within islands - Pandeng Wang; Shao‐Peng Li; Xian Yang; Jizhong Zhou; Wensheng Shu; Lin Jiang (Environmental Microbiology, 2020)
Summary The study of islands has made substantial contributions to the development of evolutionary and ecological theory. However, we know little about microbial community assembly on islands. Using soil microbial data collected from 29 lake islands and nearby mainland, we examined the assembly mechanisms of soil bacterial and fungal communities among and within islands. We found that deterministic processes, especially homogeneous selection, tended to be more important in shaping the assembly of soil bacterial communities among islands, while stochastic processes tended to be more important within islands. Moreover, increasing island area increased the importance of homogeneous selection, but reduced the importance of variable selection, for soil bacterial community assembly within islands. By contrast, stochastic processes tended to dominate soil fungal community assembly both among and within islands, with dispersal limitation playing a more important role within than among islands. Our results highlight the scale‐ and taxon‐dependence of insular soil microbial community assembly, suggesting that spatial scale should be explicitly considered when evaluating the influences of habitat fragmentation on soil microbial communities.

Effects of Dietary Supplementation of Recombinant Plectasin on Growth Performance, Intestinal Health and Innate Immunity Response in Broilers - Jing Lin Ma; Li Hua Zhao; Dan Dan Sun; Jing Zhang; Yong Peng Guo; Zhi Qiang Zhang; Qiu Gang Ma; Cheng Ji; Li Hong Zhao (Probiotics and Antimicrobial Proteins, 2020)

Scorpion Venom Heat-Resistant Peptide is Neuroprotective against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway - Xu-Gang Wang; Dan-Dan Zhu; Na Li; Yue-Lin Huang; Ying-Zi Wang; Ting Zhang; Chen-Mei Wang; Bin Wang; Yan Peng; Bi-Ying Ge; Shao Li; Jie Zhao (Neuroscience Bulletin, 2020)

Combined GWAS and QTL analysis for dissecting the genetic architecture of kernel test weight in maize - Xiaoxiang Zhang; Zhongrong Guan; Lei Wang; Jun Fu; Yinchao Zhang; Zhaoling Li; Langlang Ma; Peng Liu; Yanling Zhang; Min Liu; Peng Li; Chaoying Zou; et al. (Molecular Genetics and Genomics, 2020)

Novel B-chromosome-specific transcriptionally active sequences are present throughout the maize B chromosome - Zi-Jie Hong; Jun-Xiang Xiao; Shu-Fen Peng; Yao-Pin Lin; Ya-Ming Cheng (Molecular Genetics and Genomics, 2020)

Electroacupuncture ameliorates learning and memory deficits via hippocampal 5-HT1A receptors and the PKA signaling pathway in rats with ischemic stroke - Zhifu Wang; Bingbing Lin; Weilin Liu; Hongwei Peng; Changming Song; Jia Huang; Zuanfang Li; Lidian Chen; Jing Tao (Metabolic Brain Disease, 2020)

Interspecific interactions in dual-species biofilms of soil bacteria: effects of fertilization practices - Xiaojie Sun; Peng Cai; Søren J. Sørensen; Monika Mortimer; Chunhui Gao; Qiaoyun Huang; Yiming Wang; Xiangui Lin; Yichao Wu; Di Zhu; Ruirui Chen (Journal of Soils and Sediments, 2020)

Prolonged Neo-Tethyan magmatic arc in Myanmar: evidence from geochemistry and Sr–Nd–Hf isotopes of Cretaceous mafic–felsic intrusions in the Banmauk–Kawlin area - Jin-Xiang Li; Wei-Ming Fan; Li-Yun Zhang; Tou-Ping Peng; Ya-Li Sun; Lin Ding; Fu-Long Cai; Kyaing Sein (International Journal of Earth Sciences, 2020)

Involvement of the JNK signaling in granular corneal dystrophy by modulating TGF-β-induced TGFBI expression and corneal fibroblast apoptosis - Danyao Nie; Xinhua Liu; Yuan Wang; Wenling He; Ming Li; Yun Peng; Jing Zhang; Liangnan Sun; Zonghui Yan; Lin Ye (In Vitro Cellular & Developmental Biology - Animal, 2020)

Global buckling prevention of reduced-core-length buckling-restrained braces: theoretical and numerical investigations - Jing-Zhong Tong; Yan-Lin Guo; Wen-Hao Pan; Min-Hui Shen; Peng Zhou (Bulletin of Earthquake Engineering, 2020)

Water quality monitoring at a virtual watershed monitoring station using a modified deep extreme learning machine - Jian Jin; Peng Jiang; Lei Li; Huan Xu; Guang Lin (Hydrological Sciences Journal, 2020)

Combining GF-2 and RapidEye satellite data for mapping mangrove species using ensemble machine-learning methods - Liheng Peng; Kai Liu; Jingjing Cao; Yuanhui Zhu; Fengshou Li; Lin Liu (International Journal of Remote Sensing, 2020)

The Effects of Winter Temperature and Land Use on Mangrove Avian Species Richness and Abundance on Leizhou Peninsula, China - Quan Chen; Guorui Xu; Zhifeng Wu; Peng Kang; Qian Zhao; Yuanqi Chen; Guangxuan Lin; Shuguang Jian (Wetlands, 2020)

Strictly Lobar Cerebral Microbleeds Are Associated with Increased White Matter Volume - Pei-Ning Wang; Kun-Hsien Chou; Li-Ning Peng; Li-Kuo Liu; Wei-Ju Lee; Liang-Kung Chen; Ching-Po Lin; Chih-Ping Chung (Translational Stroke Research, 2020)

Transient Receptor Potential Ankyrin 1 Contributes to Lysophosphatidylcholine-Induced Intracellular Calcium Regulation and THP-1-Derived Macrophage Activation - Chao Tian; Rongqi Huang; Feng Tang; Zuoxian Lin; Na Cheng; Xiaobo Han; Shuai Li; Peng Zhou; Sihao Deng; Hualin Huang; Huifang Zhao; Junjie Xu; et al. (The Journal of Membrane Biology, 2020)

Vertical variation in Vibrio community composition in Sansha Yongle Blue Hole and its ability to degrade macromolecules - Bei Li; Jiwen Liu; Shun Zhou; Liang Fu; Peng Yao; Lin Chen; Zuosheng Yang; Xiaolei Wang; Xiao-Hua Zhang (Marine Life Science & Technology, 2020)
With the advantages of wide distribution, fast growth, and broad metabolic spectrum to organic carbon compounds, Vibrio may play an important role in organic carbon cycling. However, the ecological roles of Vibrio in many marine environments have not been explored. Here, the world’s deepest ‘blue hole’, the Sansha Yongle Blue Hole (SYBH) in the South China Sea, which is a geographically semi-enclosed environment featuring unique chemical characters, was investigated. The abundance, diversity and carbon source utilization capability of Vibrio were studied by quantification and high-throughput sequencing of Vibrio specific 16S rRNA genes and cultivation methods. The abundance of Vibrio in water column of the SYBH ranged from 3.78 × 10 4 to 7.35 × 10 6 16S rRNA gene copies L −1 . Free-living Vibrio was more abundant than particle-associated Vibrio (~ 1.20 × 10 6 versus~ 2.68 × 10 5 gene copies L −1 ), indicating that Vibrio prefers a free-living life style. The Vibrio assemblages showed clear vertical stratification and could be divided into three groups: aerobic-transition, middle anaerobic and bottom anaerobic zones. Dissolved oxygen (DO), temperature, pH and salinity were the main environmental factors affecting the abundance and community composition. Cultivated Vibrio demonstrated a degrading capability to various macromolecular substrates, including starch, Tween 20/40/80, DNA, gelatin, alginate, casein, chitin, lecithin, κ-carrageenan, mannan, xylan and hyaluronic acid. This suggests that Vibrio could produce a variety of highly active extracellular enzymes. Our study provides new insights into the distribution pattern and possible role in carbon cycle of Vibrio in the unique environment of a ‘blue hole’.

Erratum to: Exosome-derived galectin-9 may be a novel predictor of rejection and prognosis after liver transplantation - Ai-bin Zhang; Yi-fan Peng; Jun-jun Jia; Yu Nie; Shi-yu Zhang; Hai-yang Xie; Lin Zhou; Shu-sen Zheng (Journal of Zhejiang University-SCIENCE B, 2020)

First report of tobacco rattle virus in hydrangea in China - Zhao-Lin Ji; Peng-Xiang Zhu; Gen-He He; Yong-Hui Liao; Feng Zhu (Journal of Plant Pathology, 2020)

Analysis of Cerebrospinal Fluid Soluble TREM2 and Polymorphisms in Sporadic Parkinson’s Disease in a Chinese Population - Guoyou Peng; Jiewen Qiu; Hanqun Liu; Miaomiao Zhou; Shuxuan Huang; Wenyuan Guo; Yuwan Lin; Xiang Chen; Zhe Li; Guihua Li; Wenlong Zhang; Yunlong Zhang; et al. (Journal of Molecular Neuroscience, 2020)

Dolphin-watching tourism and indo-Pacific humpback dolphins (Sousa chinensis) in Sanniang Bay, China: impacts and solutions - Haiping Wu; Chongwei Peng; Hu Huang; Thomas A. Jefferson; Shiang-Lin Huang; Mo Chen; Qianhui Zeng; Xueying Yu; Xianyan Wang; Youhou Xu (European Journal of Wildlife Research, 2020)

The association between high particulate matter pollution and daily cause-specific hospital admissions: a time-series study in Yichang, China - Chengye Yao; Yu Wang; Christopher Williams; Chengzhong Xu; Christiana Kartsonaki; Yun Lin; Pei Zhang; Peng Yin; Kin Bong Hubert Lam (Environmental Science and Pollution Research, 2020)

Role of soluble and exchangeable nitrogen pools in N cycling and the impact of nitrogen added in forest soil - Hongliang Ma; Hüseyin Barış Tecimen; Wei Lin; Ren Gao; Yunfeng Yin; Yuanzhen Peng (Environmental Science and Pollution Research, 2020)

Nocardia panacis sp. nov., a novel actinomycete with antiphytopathogen activity isolated from the rhizosphere of Panax notoginseng - Jia-Yun Hu; Lei Li; Guang Peng; Yi-Qing Li; Li-Hua Xu; Hui-Lin Guan; Li-Xing Zhao; Cui-Ping Miao (Antonie van Leeuwenhoek, 2020)

Characterizing the spatial distribution of typical natural disaster vulnerability in China from 2010 to 2017 - Qian Wang; Qi-peng Zhang; Yang-yang Liu; Lin-jing Tong; Yan-zhen Zhang; Xiao-yu Li; Jian-long Li (Natural Hazards, 2020)

Microbiological analysis of cadmium-contaminated sediments during biostabilization with indigenous sulfate-reducing bacteria - Weihua Peng; Xiaomin Li; Manli Lin; Wenhong Fan (Journal of Soils and Sediments, 2020)

A novel sunshine duration–based photothermal time model interprets the photosensitivity of flower maturity of pecan cultivars - Hua-Lin Ye; Qun-Ying Jin; Hua-Zheng Peng; Tang-Jun Zhu; Jian-Jun Shen; Guo-Shuai Huang; Min Wang (International Journal of Biometeorology, 2020)

A New Intelligent Model for Computing Crack in Compacted Soil-Biochar Mix: Application in Green Infrastructure - Saurav Rukhaiyar; Shan Huang; Haihong Song; Peng Lin; Ankit Garg; Sanandam Bordoloi (Geotechnical and Geological Engineering, 2020)

Association between long-term occupational manganese exposure and bone quality among retired workers - Defu Li; Xiaoting Ge; Zhenfang Liu; Lulu Huang; Yanting Zhou; Peng Liu; Lian Qin; Suzhen Lin; Chaoqun Liu; Qingzhi Hou; Longman Li; Hong Cheng; et al. (Environmental Science and Pollution Research, 2020)

Revegetation of a barren rare earth mine using native plant species in reciprocal plantation: effect of phytoremediation on soil microbiological communities - Lin Zhang; Wen Liu; Shenghong Liu; Peng Zhang; Chanjuan Ye; Hong Liang (Environmental Science and Pollution Research, 2020)

Evaluation on activation energy of deposited clay based on thermo-gravimetric analysis (TGA) and four kinetics models - Rui-xin Yan; Jian-bing Peng; Yan-jun Shen; Yu-liang Zhang; Lin-jun Gu; Shao-kai Wang (Bulletin of Engineering Geology and the Environment, 2020)

Effects of irrigation method and rice straw incorporation on CH4 emissions of paddy fields in Northeast China - Tangzhe Nie; Peng Chen; Zhongxue Zhang; Zhijuan Qi; Jian Zhao; Lili Jiang; Yanyu Lin (Paddy and Water Environment, 2020)

TRY plant trait database – enhanced coverage and open access - Jens Kattge; Gerhard Bönisch; Sandra Díaz; Sandra Lavorel; Iain Colin Prentice; Paul Leadley; Susanne Tautenhahn; Gijsbert D. A. Werner; Tuomas Aakala; Mehdi Abedi; Alicia T. R. Acosta; George C. Adamidis; et al. (Global Change Biology, 2020)
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.

Characteristics, Expression Pattern and Intracellular Localisation of Sugarcane Cytoplasmic Hexokinase Gene ShHXK8 - Jun-gang Wang; Ting-ting Zhao; Ben-peng Yang; Wen-zhi Wang; Cui-lian Feng; Xiao-yan Feng; Lin-bo Shen; Shu-zhen Zhang (Sugar Tech, 2019)

l-Arginine alleviates heat stress-induced intestinal epithelial barrier damage by promoting expression of tight junction proteins via the AMPK pathway - Zhaofei Xia; Liqing Huang; Peng Yin; Fenghua Liu; Yanhan Liu; Zhenbiao Zhang; Jiabao Lin; Wenshu Zou; Chunxiao Li (Molecular Biology Reports, 2019)
Heat stress (HS) and secondary restricted blood flow to the intestines cause dysfunction of the intestinal epithelial barrier. Tight junctions (TJs) are essential to maintain intestinal integrity. l -Arginine has beneficial effects on gut functions. However, the underlying mechanisms remain largely unknown. This study tested the hypothesis that l -arginine regulates the TJ network by activating AMP-activated protein kinase (AMPK) signaling, which in turn improves intestinal barrier functions under HS. IEC-6 cells and rat small intestines were used as experiment models of heat stress. AICAR and dorsomorphin were used to activate and inhibit the AMPK pathway, respectively. Cell proliferation, apoptosis, differential gene expression and KEGG pathway analysis, intestinal paracellular permeability, intestinal morphology, and expression of HSP and TJ proteins, and p-AMPK were determined. l -Arginine promoted cell proliferation and reduced apoptosis after heat exposure at an optimal concentration of 5 mmol. Transcriptome sequencing analysis revealed that differentially expressed genes associated with the HSP family and TJs were elevated by l -arginine. According to KEGG pathway analysis, l -arginine activated the AMPK signaling pathway. In vivo, intestinal damage resulted in obvious morphological changes as well as apoptosis with TUNEL and caspase-3 staining under HS and dorsomorphin treatments. Furthermore, HS and dorsomorphin increased the serum D-lactate concentration, diamine oxidase activity, and mRNA expression level of MLCK ( P < 0.05). In contrast, l -arginine and AICAR treatments reduced intestinal injury, maintained intestinal permeability, and increased the villus/crypt ratio under hyperthermia. l -Arginine had the same effect as AICAR both in vitro and in vivo, namely increasing p-AMPK protein expression. l -Arginine and AICAR also upregulated the mRNA expression level of HSP70 and HSP90, and downregulated mRNA expression of MLCK ( P < 0.05). The protein expression levels of TJ proteins ZO-1 and claudin-1 were suppressed by heat stroke and dorsomorphin, but enhanced by l -arginine and AICAR. Our findings indicate that activation of AMPK signaling by l -arginine is associated with improved intestinal mucosal barrier functions by enhancing the expression of TJs in rat small intestines and IEC-6 cells during HS.

Cloning and expression analysis of the StCUL1 gene in potato - Peng-Xiang Pang; Li Shi; Xiao-Juan Wang; Yan-Nan Chang; Yong-Ping Luo; Jin-Lin Feng; Hemu Eri; Gang Gao (Journal of Plant Biochemistry and Biotechnology, 2019)

Phosphorus addition accelerates fine root decomposition by stimulating extracellular enzyme activity in a subtropical natural evergreen broad-leaved forest - Chengfang Lin; Weisheng Lin; Silu Chen; Jianqun Peng; Jianfen Guo; Yusheng Yang (European Journal of Forest Research, 2019)

Addition of zeolite and superphosphate to windrow composting of chicken manure improves fertilizer efficiency and reduces greenhouse gas emission - Shuang Peng; Huijie Li; Qianqian Xu; Xiangui Lin; Yiming Wang (Environmental Science and Pollution Research, 2019)

Experimental and numerical study of the water inrush mechanisms of underground tunnels due to the proximity of a water-filled karst cavern - Dongdong Pan; Shucai Li; Zhenhao Xu; Peng Lin; Xin Huang (Bulletin of Engineering Geology and the Environment, 2019)

Shallow unloading deformation analysis on Baihetan super-high arch dam foundation - Peng Lin; Jie Shi; Pengcheng Wei; Qixiang Fan; Zhilin Wang (Bulletin of Engineering Geology and the Environment, 2019)

Transcriptome analysis in different chieh-qua cultivars provides new insights into drought-stress response - Min Wang; Xiaoming He; Biao Jiang; Wenrui Liu; Yu’e Lin; Dasen Xie; Zhaojun Liang; Lihui Chen; Qingwu Peng (Plant Biotechnology Reports, 2019)