An effective tool for tracking steroids and their metabolites at the watershed level: Combining fugacity modeling and a chemical indicator - Ru Xu; Shan Liu; Hui Chen; Qin-Wei Hao; Yong-Xia Hu; Heng-Xiang Li; Lang Lin; Rui Hou; Bing Hong; Shen Yu; Xiang-Rong Xu (Environmental Pollution, 2023)

BasinMaker 3.0: A GIS toolbox for distributed watershed delineation of complex lake-river routing networks - Ming Han; Hongren Shen; Bryan A. Tolson; James R. Craig; Juliane Mai; Simon G.M. Lin; Nandita B. Basu; Frezer S. Awol (Environmental Modelling & Software, 2023)

Extremely weak Lg attenuation reveals ancient continental relicts in the South China block - Lin Shen; Lian-Feng Zhao; Xiao-Bi Xie; Geng Yang; Zhen-Xing Yao (Earth and Planetary Science Letters, 2023)

High-breathable, antimicrobial and water-repellent face mask for breath monitoring - Fangfei Zhang; Junzhu Lin; Mingwan Yang; Yun Wang; Zhicheng Ye; Jiajun He; Jie Shen; Xuechang Zhou; Zhiguang Guo; Yabin Zhang; Ben Wang (Chemical Engineering Journal, 2023)

Tuning the reactivity and energy release efficiency in aluminum alloy thermite by eutectic silicon - Lixiao Shen; Yan Li; Lin Zhang; Shunguan Zhu; Zhenxin Yi; Chenguang Zhu (Chemical Engineering Journal, 2023)

Manganese-based flow battery based on the MnCl2 electrolyte for energy storage - Yuqin Liu; Mingjun Nan; Zichao Zhao; Bo Shen; Lin Qiao; Huamin Zhang; Xiangkun Ma (Chemical Engineering Journal, 2023)

Histone modification landscape and the key significance of H3K27me3 in myocardial ischaemia/reperfusion injury - Le Ni; Bowen Lin; Yanping Zhang; Lingjie Hu; Jianghua Lin; Fengmei Fu; Meiting Shen; Can Li; Lei Chen; Jian Yang; Dan Shi; Yi-Han Chen (Science China Life Sciences, 2023)

Exogenous Methylglyoxal Ameliorates Source Strength and Retrieves Yield Loss Under Drought Stress During Grain Filling in Maize - Yi-Hsuan Lin; Yu-Ka Jin; Zhen-Yuan Chen; Zu-Dong Xiao; Si Shen; Shun-Li Zhou (Journal of Plant Growth Regulation, 2023)

Occurrence, Degradation Pathways, and Potential Synergistic Degradation Mechanism of Microplastics in Surface Water: A Review - Lihua Niu; Yingjie Wang; Yi Li; Li Lin; Yamei Chen; Jiayan Shen (Current Pollution Reports, 2023)

Characterization of lacustrine harmful algal blooms using multiple biomarkers: Historical processes, driving synergy, and ecological shifts - Qi Lin; Ke Zhang; Suzanne McGowan; Shixin Huang; Qingju Xue; Eric Capo; Can Zhang; Cheng Zhao; Ji Shen (Water Research, 2023)

Metabolic and transcriptional responses demonstrating enhanced thermal tolerance in domesticated abalone - Feng Yu; Yawei Shen; Wenzhu Peng; Nan Chen; Yang Gan; Qizhen Xiao; Junyu Liu; Yisha Lu; Weihong Lin; Zhaofang Han; Xuan Luo; Weiwei You; et al. (Science of The Total Environment, 2023)

OsCIP1, a secreted protein, binds to and stabilizes OsCR4 to promote aleurone layer development, seed germination and early seedling growth in rice - Lin-Lin Yan; Jing Mi; Can-Can Shen; Rong Qian; Jiao Wang; Cui-Xia Pu; Ying Sun (Plant Science, 2023)

Enhanced photo-electro-Fenton degradation performance using graphene structure-oriented MOFs (2Fe/Co)/CNF cathode membrane - Bingzhang Li; Yao Meng; Xiaoxia Lin; Degui Tu; Shunxi Shen; Ting He; Yuqi Li; Hui Zhang (Journal of Cleaner Production, 2023)

Carbon-confined Ni based catalyst by auto-reduction for low-temperature dry reforming of methane - Dongyang Shen; Jie Wang; Yue Bai; Shuai Lyu; Yuhua Zhang; Jinlin Li; Lin Li; Guanghui Wang (Fuel, 2023)

In-situ construction of hexagonal-star-shaped MnCo2S4@MoS2 boosting overall water splitting performance at large-current-density: Compositional-electronic regulation, functions, and mechanisms - Tiantian Ma; Xueran Shen; Qingze Jiao; Yun Zhao; Hansheng Li; Yaoyuan Zhang; Yuzhen Lv; Caihong Feng; Lin Guo (Chemical Engineering Journal, 2023)

Metabolomics reveals size-dependent persistence and reversibility of silver nanoparticles toxicity in freshwater algae - Lin Shen; Qin Qin Li; Yu Hang Kang; Qian Qian Xiang; Xia Luo; Li Qiang Chen (Aquatic Toxicology, 2023)

Double-negative T cells: a promising avenue of adoptive cell therapy in transplant oncology - Zhihang Hu; Modan Yang; Hao Chen; Chiyu He; Zuyuan Lin; Xinyu Yang; Huigang Li; Wei Shen; Di Lu; Xiao Xu (Journal of Zhejiang University-SCIENCE B, 2023)

Overview of the main biological mechanisms linked to changes in periodontal ligament stem cells and the inflammatory microenvironment - Xuetao Zhao; Hongbing Lin; Tong Ding; Yawei Wang; Na Liu; Yuqin Shen (Journal of Zhejiang University-SCIENCE B, 2023)

Field experiments on quantifying the contributions of Coreopsis canopies and roots to controlling runoff and erosion on steep loess slopes - Yu-wei Gong; Hai-jun Yu; Pei Tian; Wen-zhao Guo; Lin Chen; Ding-tao Shen (Journal of Mountain Science, 2023)

Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy - Xiaomin Chen; Jiahui Liu; Jun Li; Yinpeng Xie; Zichen Yu; Lu Shen; Qingfeng Liu; Wei Wu; Qiang Zhao; Haoxiang Lin; Gaotong Liu; Qiuping Luo; et al. (Genes & Genomics, 2023)

Identifying the effects of cropping with different pear cultivars on microbial community composition and networks in orchard soils - Li Wang; Xiaomei Ye; Zongzhuan Shen; Yingpeng Zhang; Jing Lin (Environmental Science and Pollution Research, 2023)

Nitrogen addition enhanced Per-fluoroalkyl substances’ microbial availability in a wheat soil ecosystem - Jian-yi Wu; Zhi-wei Shen; Zu-lin Hua; Li Gu (Chemosphere, 2023)

Effects of biodegradation, biotoxicity and microbial community on biostimulation of sulfolane - Shao-Heng Chang; Chi-Wen Lin; Yu-Shen Cheng; Shu-Hui Liu (Chemosphere, 2023)

Variable p53/Nrf2 crosstalk contributes to triptolide-induced hepatotoxic process - Zhenyan Hou; Miao Yan; Huixiang Li; Weida Wang; Shen You; Mingjin Wang; Tingting Du; Hui Gong; Wenqun Li; Lin Guo; Shanshan Wei; Bikui Zhang; et al. (Toxicology Letters, 2023)

Studies on the interaction of five triazole fungicides with human renal transporters in cells - Jing Nie; Jiabei Zhou; Yi Shen; Ruimiao Lin; Haihong Hu; Kui Zeng; Huichang Bi; Min Huang; Lushan Yu; Su Zeng; Jing Miao (Toxicology in Vitro, 2023)

Simultaneous adsorption and biodegradation of polychlorinated biphenyls using resuscitated strain Streptococcus sp. SPC0 immobilized in polyvinyl alcohol‑sodium alginate - Qihua Lin; Jiayan Ding; Yingying Yang; Faqian Sun; Chaofeng Shen; Hongjun Lin; Xiaomei Su (Science of The Total Environment, 2023)

Oxygen-terminated vanadium carbide with graphitic carbon nitride nanosheets modified electrode: A robust electrochemical platform for the sensitive detection of antibiotic drug clioquinol - Ramadhass Keerthika Devi; Muthusankar Ganesan; Tse-Wei Chen; Shen-Ming Chen; Muthumariappan Akilarasan; Syang-Peng Rwei; Jaysan Yu; Kuan-Yu Lin; Anlin Shaju (Process Safety and Environmental Protection, 2023)

Ultrapotassic enclaves in the Miocene adakitic granitoids, southern Tibet: Direct evidence for collision-related crust-mantle interaction and its implications - Chang-da Wu; Yuan-chuan Zheng; Bo Xu; Zeng-qian Hou; Peng Chai; Xin Li; Lin-yuan Zhang; Zi-xuan Wang; Lu Wang; Yang Shen (Lithos, 2023)

A novel strategy for enhancing bioremediation of polychlorinated biphenyl-contaminated soil with resuscitation promoting factor and resuscitated strain - Xinru Zhou; Shusheng Zhang; Rui Wang; Zijing An; Faqian Sun; Chaofeng Shen; Hongjun Lin; Xiaomei Su (Journal of Hazardous Materials, 2023)

Emulsifier free fish gelatin based films with excellent antioxidative and antibacterial activity: Preparation, characterization and application in coating preservation of fish fillets - Gaojie Song; Sheng Lin; Yuesheng Wu; Jiaping Shen; Jiulin Wu; Wenjin Zhu; Shuna Yu; Jianhua Li; Shaoyun Wang (Journal of Food Engineering, 2023)

4D printing system stimulated by curcumin/whey protein isolate nanoparticles: A comparative study of sensitive color change and post-processing - Chen Shen; Wenqing Chen; Changzhu Li; Xiaochen Chen; Haiying Cui; Lin Lin (Journal of Food Engineering, 2023)

Accelerated carbonation of ball-milling modified MSWI fly ash: Migration and stabilization of heavy metals - Jie Chen; Yizhe Shen; Zhiliang Chen; Congkai Fu; Minjie Li; Tieying Mao; Ruiyang Xu; Xiaoqing Lin; Xiaodong Li; Jianhua Yan (Journal of Environmental Chemical Engineering, 2023)

Facile immunochromatographic assay based on metal–organic framework-decorated polydopamine for the determination of hydrochlorothiazide adulteration in functional foods - Zhiwei Liu; Zixian He; Jinxiao Wu; Houliang lin; Youwen Deng; Xing Shen; Hongtao Lei; Xiangmei Li (Food Chemistry, 2023)

Yield gap of rice genotypes under N and P deficiencies: Evidence from differential recruitment of bacterial keystone taxa in the rhizosphere - Jia Lin Wang; Xun Xiao; An Yong Hu; Ren Fang Shen; Xue Qiang Zhao (Applied Soil Ecology, 2023)

Evaluation of a subtropical maize-rice rotation system maintained under long-term fertilizer inputs for sustainable intensification of agriculture - Asif Hameed; Yu-Pei Chen; Fo-Ting Shen; Shih-Yao Lin; Hsin-I Huang; Yu-Wen Lin; Chiu-Chung Young (Applied Soil Ecology, 2023)

Paper-based analytical device coupled with Bi-MOF: Electric field amplification and fluorescence sensing of glyphosate - Chao-Qun Wan; Yue-Hong Pang; Qiu-Yu Yang; Cheng-Lin Yang; Xiao-Fang Shen (Analytica Chimica Acta, 2023)

Whole-genome sequencing reveals putative underlying mechanisms of biocontrol capability of IBFCBF-5 - Chen Luo; Ai-rong Shen; Ye-song Ren; Yang Zhai; Yi Cheng; Jianping Xu; Lin Wei; Ji-lie Li; Liang-bin Zeng (Acta Physiologiae Plantarum, 2023)

Duplicate genes as sources for rapid adaptive evolution of sperm under environmental pollution in tree sparrow - Shengnan Wang; Yingmei Zhang; Wenzhi Yang; Yue Shen; Zhaocun Lin; Sheng Zhang; Gang Song (Molecular Ecology, 2023)
Environmental pollution can result in poor sperm quality either directly or indirectly in birds. However, adaptive and compensatory sperm morphology changes and motility improvements have rapidly evolved in tree sparrows ( Passer montanus ) inhabiting polluted areas over the past 65 years. To identify the genetic underpinnings of the rapidly evolving sperm phenotype, we carried out population genomics and transcriptomics on tree sparrow populations in the two differently polluted places. We identified a gene encoding the serine/threonine protein kinase PIM1, which may drive rapid phenotypic evolution of sperm. An unprecedented and remarkable expansion of the PIM gene family, caused by tandem and segmental duplication of PIM1 , was subsequently observed in the tree sparrow genome. Most PIM1 duplicates showed a testis‐specific expression pattern, suggesting that their functions are related to male reproduction. Furthermore, the elevated expression level of PIM1 was consistent with our earlier findings of longer and faster swimming sperm in polluted sites, indicating an important role for duplicated PIM1 in facilitating the rapid evolution of sperm. Our results suggest that duplicated PIM1 provides sources of genetic variation that may enable the rapid evolution of sperm under environmental heavy metal pollution. The findings of this study indicated that duplicated genes can be targets of selection and predominant sources for rapid adaptation to environmental change and shed light on sperm evolution under pollution stress.

Association between long-term exposure to air pollution and the risk of incident laryngeal cancer: a longitudinal UK Biobank-based study - Jiada Wang; Chen Lin; Yidian Chu; Hongxia Deng; Zhisen Shen (Environmental Science and Pollution Research, 2023)
We assessed the association between long-term joint exposure to ambient air pollutants and the risk of laryngeal cancer and whether this risk was modified by genetic susceptibility. We used a multivariable Cox proportional hazards regression model to analyze data from UK Biobank to determine the relationship between long-term exposure to air pollutants–nitric oxide (NO), nitrogen dioxide (NO 2 ), and 2.5- µ m and 10- µ m particulate matter (PM 2.5 and PM 10 ) and the risk of laryngeal cancer. In multivariable-adjusted models, in model 3 and compared with the participants with lower quintile scores for air pollution, the participants with the highest quintile scores for air pollution had a higher laryngeal cancer risk. The observed association was more pronounced among the participants who were female, were smokers, had a systolic blood pressure equal to or greater than 120 mmHg, and had diabetes. Compared with the participants with a low GRS and the lowest quintile score for air pollution exposure, those with an intermediate GRS and the highest quintile score for air pollution exposure had a higher risk of laryngeal cancer. Long-term exposure to NO 2 , NO, or PM 2.5 , individually or jointly, was associated with a risk of incident laryngeal cancer, especially in the participants with an intermediate GRS.

The numerical simulation of the multilayered bounded domain with side face load by the modified SBFEM - Shan Lu; Gao Lin; Lu Shen; Jian Su (European Journal of Environmental and Civil Engineering, 2023)

Biosensors for detection of paralytic shellfish toxins: Recognition elements and transduction technologies - Liu-Na Wei; Lin Luo; Bing-Zhi Wang; Hong-Tao Lei; Tian Guan; Yu-Dong Shen; Hong Wang; Zhen-Lin Xu (Trends in Food Science & Technology, 2023)

Dispersal limitation and host selection drive geo-specific and plant-specific differentiation of soil bacterial communities in the Tibetan alpine ecosystem - Sai Qu; Congcong Shen; Lin Zhang; Jichen Wang; Li-Mei Zhang; Baodong Chen; Guo-Xin Sun; Yuan Ge (Science of The Total Environment, 2023)

Cold spells linked with respiratory disease hospitalization, length of hospital stay, and hospital expenses: Exploring cumulative and harvesting effects - Jin Feng; Dawei Cao; Dashan Zheng; Zhengmin (Min) Qian; Cunrui Huang; Huiqing Shen; Yi Liu; Qiyong Liu; Jimin Sun; Guangyuan Jiao; Xiaoran Yang; Stephen Edward McMillin; et al. (Science of The Total Environment, 2023)

Construction of perovskite structured ZnSnO3 embedded graphene oxide nanosheets for in-situ electrochemical quantification of organoarsenic roxarsone - Elayappan Tamilalagan; Muthumariappan Akilarasan; Shen-Ming Chen; Mani Govindasamy; Kuan-Yu Lin; Fatimah Mohammed Alzahrani; Norah Salem Alsaiari (Process Safety and Environmental Protection, 2023)

Evaluation of environmental impact of red tide around Pearl River Estuary, Guangdong, China - Yu-Lin Chen; Lin-Shuang Zhao; Annan Zhou; Shui-Long Shen (Marine Environmental Research, 2023)

Metagenomic study of carbon metabolism in black soil microbial communities under lead-lanthanum stress - Yue Tao; Lu Shen; Siyue Han; Zixu Li; Yunhe Cui; Yulong Lin; Jianhua Qu; Ying Zhang (Journal of Hazardous Materials, 2023)

Aflatoxin B1 exposure triggers hepatic lipotoxicity via p53 and perilipin 2 interaction-mediated mitochondria-lipid droplet contacts: An in vitro and in vivo assessment - Lin Che; Jing Huang; Jin-Xian Lin; Chi-Yu Xu; Xin-Mou Wu; Ze-Bang Du; Jia-Shen Wu; Zhong-Ning Lin; Yu-Chun Lin (Journal of Hazardous Materials, 2023)

Exploring key physicochemical sediment properties influencing bioleaching of heavy metals - Chuncheng Wu; Xinyi Hu; Haizhen Wang; Qi Lin; Chaofeng Shen; Liping Lou (Journal of Hazardous Materials, 2023)

A 13 million-year record of Li isotope compositions in island carbonates: Constraints on bulk inorganic carbonate as a global seawater Li isotope archive - Guang-Yi Wei; Feifei Zhang; Yi-Sheng Yin; Yi-Bo Lin; Philip A.E. Pogge von Strandmann; Mengchun Cao; Na Li; Guolin Xiong; Xinran Chen; Caiwei Fan; Changgui Xu; Fei Tan; et al. (Geochimica et Cosmochimica Acta, 2023)

Reducing the background interference of liquid–liquid extraction method during Baijiu aroma analysis - Wei Dong; Wenxuan Lin; Xiaoman Chen; Xudong Lian; Caihong Shen; Miao Liu; Feng Lin; Xiaotao Sun; Youqiang Xu; Yanfei Xiong; Bo Deng (Food Chemistry, 2023)

Topical advances of edible coating based on the nanoemulsions encapsulated with plant essential oils for foodborne pathogen control - Chen Shen; Wenqing Chen; Changzhu Li; Tariq Aziz; Haiying Cui; Lin Lin (Food Control, 2023)

An efficient model to estimate the soil profile and stratigraphic uncertainty quantification - Lin-Shuang Zhao; Shuaihe Zhuo; Bingqing Shen (Engineering Geology, 2023)

Graphene oxide assisted assembly of superhydrophilic MOF-based membrane with 2D/3D hybrid nanochannels for enhanced water purification - Lingya Fei; Cheng Chen; Liguo Shen; Yuyao Zhang; Boya Wang; Jiujing Xu; Bisheng Li; Saleem Raza; Hongjun Lin (Chemical Engineering Journal, 2023)

Unveiling the interaction mechanism between facet-dependent pyrite nanoparticles and Cr(VI) under anaerobic environment: adsorption, redox, and phase transformation - Chenrui Liu; Yun Liu; Wentao Shen; Shuangyi Lin; Hao He; Fan Li; Feng Li; Jiang Tian (Chemical Engineering Journal, 2023)

Self-supply of H2O2 and O2 by a composite nanogenerator for chemodynamic therapy/hypoxia improvement and rapid therapy of biofilm-infected wounds - Junjie Wu; Peng Shen; Xian Qin; Yulu Yang; Chuanchuan Lin; Xuan Li; Wenbo Geng; Pengfei Gao; Lixue Chen; Li Miao; Yang Jiao; Bailong Tao (Chemical Engineering Journal, 2023)

Nanocellulose: An amazing nanomaterial with diverse applications in food science - Fengrui Zhang; Rui Shen; Nan Li; Xingbin Yang; Dehui Lin (Carbohydrate Polymers, 2023)

Aluminum-Tolerant Wheat Genotype Changes Root Microbial Taxa and Nitrogen Uptake According to Soil pH Levels and Nitrogen Rates - Xin Jun Dai; Jia Lin Wang; Xun Xiao; Xiao Ying Dong; Ren Fang Shen; Xue Qiang Zhao (Journal of Soil Science and Plant Nutrition, 2023)

Knockout of the LW opsin gene interferes with oviposition selection of nocturnal moth, Helicoverpa armigera - Xiaoming Liu; Limei Cai; Lin Zhu; Zhiqiang Tian; Zhongjian Shen; Jie Cheng; Songdou Zhang; Zhen Li; Xiaoxia Liu (Journal of Pest Science, 2023)

Construction and validation of a bladder cancer risk model based on autophagy-related genes - Chong Shen; Yan Yan; Shaobo Yang; Zejin Wang; Zhouliang Wu; Zhi Li; Zhe Zhang; Yuda Lin; Peng Li; Hailong Hu (Functional & Integrative Genomics, 2023)

Preparation of laser microporous porcine acellular dermal matrix and observation of wound transplantation - Weidong Xia; Cai Lin; Zhuolong Tu; Yuan Li; Guoliang Shen (Cell and Tissue Banking, 2023)
To prepare a new type of porcine acellular dermis matrix (PADM) with the new laser microporous technique and verify its safety and feasibility. A novel porcine acellular dermis matrix (ADM) was prepared by using sequential combined decellularization of trypsin, neutral protease and SDS solution method and fully rinsed with ultrasonic wave. Specific laser microporous technology was used to prepare the laser micropore porcine acellular dermal matrix (LPADM). SD rats were chose as the animal models and autologous skin was transplanted by one-step method to observe and detect the graft activity, immunogenicity and vascularization degree of the novel PADM. A porcelain white, shiny, soft and elastic dermal matrix was prepared in this study, the results showed low DNA residue and low cytotoxicity. HE staining and SEM observation revealed that the PADM had neither residual cells nor cell fragments, while the collagen bundles were intact and orderly arranged. All the SD rats survived. No infection or skin allergy was found after surgery. None of the animals lost weight. Histological examination showed that the LPADM was fully vascularized with little tissue destruction in the experiment group. Immunohistochemical staining for CD31 showed ideal vascularization in the experiment group, and immunohistochemical staining for TNF-α showed there were no statistical significance of inflammatory reaction in both groups. This study demonstrated that the novel PADM prepared by sequential combined decellularization of trypsin, neutral protease and SDS solution method and new laser microporous technique was effective and safe in animal transplantation.

Metabolic reprogramming of Helicoverpa armigera larvae by HearNPV facilitates viral replication and host immune suppression - Zhiqiang Tian; Lin Zhu; J. P. Michaud; Meng Zha; Jie Cheng; Zhongjian Shen; Xiaoming Liu; Xiaoxia Liu (Molecular Ecology, 2023)
Baculoviruses are highly evolved parasites that genetically reprogram the developing phenotype of their host insect to produce a vessel for virus replication and dispersal. Here we show that larvae of Helicoverpa armigera infected with HearNPV accumulate glucose in the midgut, which reduces food consumption and alters the dynamics of pathways governing metabolism and immunity. We used transcriptomics to demonstrate the role of the insulin signalling pathway in regulating the HearNPV infection process. Dietary restriction decreased mortality of infected larvae and reduced viral replication prior to death, whereas dietary supplementation with glucose produced the opposite effects. The expression of most tricarboxylic acid cycle (TCA) and energy metabolism‐related genes was reduced in infected larvae, whereas the expression of immunity‐, glycolysis‐ and insulin‐related genes was enhanced. Treatment of infected larvae with insulin increased their survival, reduced viral replication and inhibited climbing behaviour compared to a control treatment with DMSO, whereas RNAi suppression of the insulin receptor gene produced the opposite effects. Inhibition of glycolysis with dichloroacetate (DCA) promoted viral replication and accelerated larval death, but inhibition of the TCA cycle with 2‐deoxyglucose (2‐DG) did not, although both diminished climbing behaviour. This work demonstrates that successful baculovirus infections hinge on metabolic reprogramming of the host and concurrent suppression of immune responses in the larval midgut, with the insulin signalling pathway mediating a trade‐off between glucose metabolism and virus resistance.

Risk assessment and environmental determinants of urinary phthalate metabolites in pregnant women in Southwest China - Nian Wu; Lin Tao; Kunming Tian; Xia Wang; Caidie He; Songlin An; Yingkuan Tian; Xiang Liu; Wei Chen; Haonan Zhang; Pei Xu; Dengqing Liao; et al. (Environmental Science and Pollution Research, 2023)

3D printing titanium dioxide-acrylonitrile-butadiene-styrene (TiO2-ABS) composite membrane for efficient oil/water separation - Lei Han; Liguo Shen; Hongjun Lin; Zhengyi Huang; Yanchao Xu; Renjie Li; Bisheng Li; Cheng Chen; Wei Yu; Jiaheng Teng (Chemosphere, 2023)

Perfluorooctanoic acid and perfluorooctanesulfonic acid induce immunotoxicity through the NF-κB pathway in black-spotted frog (Rana nigromaculata) - Zhiquan Liu; Huikang Lin; Yueyue Zheng; Yixuan Feng; Chaoli Shi; Ruoxin Zhu; Xingyao Shen; Yu Han; Hangjun Zhang; Yuchi Zhong (Chemosphere, 2023)

Enhancing mechanical and photocatalytic properties by surface microstructure regulation of TiO2 nanofiber membranes - Xilin Liao; Hai-Tao Ren; Baolei Shen; Jia-Horng Lin; Ching-Wen Lou; Ting-Ting Li (Chemosphere, 2023)

Unveiling the impact of imidazole derivative with mechanistic insights into neutralize interfacial polymerized membranes for improved solute-solute selectivity - Titik Istirokhatun; Yuqing Lin; Ken Kinooka; Qin Shen; Pengfei Zhang; Yuandong Jia; Atsushi Matsuoka; Kazuo Kumagai; Tomohisa Yoshioka; Hideto Matsuyama (Water Research, 2023)

High propensity of membrane fouling and the underlying mechanisms in a membrane bioreactor during occurrence of sludge bulking - Mengfei Wu; Meijia Zhang; Liguo Shen; Xinhua Wang; Deng Ying; Hongjun Lin; Renjie Li; Yanchao Xu; Huachang Hong (Water Research, 2023)

A pH- and enzymatic-responsive nanopesticide to control pea aphids and reduce toxicity for earthworms - Xuqian Zhang; Ying He; Zitong Yuan; Guangmao Shen; Zan Zhang; Jinzhi Niu; Lin He; Jinjun Wang; Kun Qian (Science of The Total Environment, 2023)

Changes in permafrost spatial distribution and active layer thickness from 1980 to 2020 on the Tibet Plateau - Tongqing Shen; Peng Jiang; Qin Ju; Zhongbo Yu; Xuegao Chen; Hui Lin; Yueguan Zhang (Science of The Total Environment, 2023)

Spatial effects of urban green infrastructure on instream water quality assessed by chemical and sensory indicators - Juan Li; Shen Yu; Bing Hong; Ruihan Lin; Qi Li; Linlin Zhang; Tao Lin; Haifeng Jia; Dawen Yang; Chengwei Gu; Qimeng Jia (Science of The Total Environment, 2023)

Association of walkability and fine particulate matter with chronic obstructive pulmonary disease: A cohort study in China - Yonghao Wu; Peng Shen; Zongming Yang; Luhua Yu; Zhanghang Zhu; Tiezheng Li; Lisha Xu; Dan Luo; Xuecheng Yao; Xinhan Zhang; Lin Meng; Hongbo Lin; et al. (Science of The Total Environment, 2023)

Newly isolated halotolerant Aspergillus sp. showed high diesel degradation efficiency under high salinity environment aided with hematite - Sumbal Sajid; Víctor Resco de Dios; Obey Kudakwashe Zveushe; Farhan Nabi; Songrong Shen; Qianlin Kang; Lei Zhou; Lin Ma; Wei Zhang; Yulian Zhao; Ying Han; Faqin Dong (Journal of Hazardous Materials, 2023)

Exploring Br-’s roles on non-brominated NDMA formation during ozonation: Reactive oxygen species contribution and brominated intermediate path validation - Menglan Gao; Xiaobin Liao; Jing Yu; Xinna Lin; Huan Qi; Linlu Shen; Shupo Liu; Zhimin Yang (Journal of Hazardous Materials, 2023)

Effect of species, muscle location, food processing and refrigerated storage on the fish allergens, tropomyosin and parvalbumin - Chia-Lin Tsai; Kristy Perng; Yu-Chen Hou; Cheng-Jou Shen; I-Ning Chen; Yi-Tien Chen (Food Chemistry, 2023)

PH sensitive double-layered emulsions stabilized by bacterial cellulose nanofibers/soy protein isolate/chitosan complex enhanced the bioaccessibility of curcumin: In vitro study - Rui Shen; Xingbin Yang; Dehui Lin (Food Chemistry, 2023)

Extraction and characterization of pectic polysaccharides from Choerospondias axillaris peels: Comparison of hot water and ultrasound-assisted extraction methods - Chao Wang; Jing Li; Yi Cao; Jialu Huang; Hongyi Lin; Tiantian Zhao; Lu Liu; Peiyi Shen; David Julian McClements; Jun Chen; Chengmei Liu; Jiyan Liu; et al. (Food Chemistry, 2023)

Bacillus subtilis reduces antibiotic resistance genes of animal sludge in vermicomposting by improving heat stress tolerance of Eisenia foetida and bacterial community adjustment - Xiaoxia Hao; Wenjin Zhang; Liangbin Zhao; Linyuan Shen; Li Zhu; Bo Zeng; Dongmei Jiang; Lin Bai (Environmental Research, 2023)

Using a human bronchial epithelial cell-based malignant transformation model to explore the function of hsa-miR-200 family in the progress of PM2.5-induced lung cancer development - Wanli Ma; Lin Xu; Xueying Sun; Yuan Qi; Shen Chen; Daochuan Li; Yuan Jin; Ningning Chen; Xiaoxiao Zhu; Jiao Luo; Chuanhai Li; Kunming Zhao; et al. (Environmental Pollution, 2023)

The role of branched alkylthio side chain on dispersion and thermoelectric properties of regioregular polythiophene/carbon nanotubes nanocomposites - Po-Shen Lin; Shin Inagaki; Jia-Hao Liu; Ming-Chou Chen; Tomoya Higashihara; Cheng-Liang Liu (Chemical Engineering Journal, 2023)

Engineering metal–organic frameworks (MOFs) based thin-film nanocomposite (TFN) membranes for molecular separation - Die Ling Zhao; Fan Feng; Liguo Shen; Zhengyi Huang; Qipeng Zhao; Hongjun Lin; Tai-Shung Chung (Chemical Engineering Journal, 2023)

A gas permeable membrane electrode for selective and durable H2S production from SO2 - Hui Liu; Xudong Liu; Zhujiang Wang; Huimin Yi; Yingxue Fu; Lin Wu; Fenghua Shen; Pingshan Wang; Min Liu; Zhang Lin; Kaisong Xiang; Liyuan Chai (Chemical Engineering Journal, 2023)

Synergistically enhanced structural, thermal and interfacial stability of K0.45MnO2 via tailoring the local structure for high-energy and high-power potassium-ion batteries - Yan Huang; Xinyuan Zhang; Hezhe Lin; Zhixuan Wei; Yi Zeng; Xin Ge; Wei Zhang; Xiaoqi Wang; Xu Jin; Ze Xiang Shen; Fei Du (Chemical Engineering Journal, 2023)

Epoxy-functionalized polyethyleneimine modified epichlorohydrin-cross-linked cellulose aerogel as adsorbents for carbon dioxide capture - Xinjie Chen; Jian Lin; Hanwei Wang; Yushan Yang; Chao Wang; Qingfeng Sun; Xiaoping Shen; Yingying Li (Carbohydrate Polymers, 2023)

Structure, Intracellular Localisation and Expression Analysis of Sucrose Nonfermenting-Related Kinase ShSnRK1α in Sugarcane - Ting-ting Zhao; Jun-gang Wang; Wen-zhi Wang; Cui-lian Feng; Xiao-yan Feng; Lin-bo Shen; Shu-zhen Zhang (Sugar Tech, 2023)

Ihog proteins contribute to integrin-mediated focal adhesions - Yun Qi; Han Liu; Kang Zhang; Yihui Wu; Chenghao Shen; Xinhua Lin (Science China Life Sciences, 2023)

Compound Probiotic Ameliorates Acute Alcoholic Liver Disease in Mice by Modulating Gut Microbiota and Maintaining Intestinal Barrier - Haixia Liu; Xing Kang; Xiaodan Yang; Hao Yang; Xiaoyu Kuang; Peng Ren; Huan Yan; Xiaorong Shen; Yongbo Kang; Lin Li; Xiaohui Wang; Linzhi Guo; et al. (Probiotics and Antimicrobial Proteins, 2023)

Impact of miR-200b and miR-495 variants on the risk of large-artery atherosclerosis stroke - Shanmei Qin; Chong Shen; Wuzhuang Tang; Mengmeng Wang; Ying Lin; Zhaojun Wang; Yunzi Li; Zhizhong Zhang; Xinfeng Liu (Metabolic Brain Disease, 2023)

Coexistence of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and IgA nephropathy - Qi Xiong; Wei Lin; Chanjuan Shen; Ting Meng; Rong Tang; Joshua D. Ooi; Peter J. Eggenhuizen; Jinbiao Chen; Wannian Nie; Xia Li; Qiaoling Zhou; Ping Xiao; et al. (Immunologic Research, 2023)

Export of Greenland Sea water across the Mohn Ridge induced by summer storms - Xusiyang Shen; Jinping Zhao; Xiaoyu Wang; Tore Hattermann; Wenqi Shi; Long Lin; Ping Chen (Acta Oceanologica Sinica, 2023)

Nitrogen mineralization and immobilization in surface sediments of coastal reclaimed aquaculture ecosystems - Xianbiao Lin; Genmei Lin; Yijie Zheng; Wenjing Li; Peng Guo; Shiyuan Fan; Tiantian Kong; Dongfan Tian; Dongyao Sun; Zhuo Shen (Frontiers in Marine Science, 2023)
Sediment nitrogen (N) mineralization and immobilization are two crucial processes driven by microorganisms, which may play significant roles in the regulation of water quality in aquaculture ecosystems. However, limited information is available about the quantitative importance of sedimentary N mineralization and immobilization in coastal aquaculture systems. Here, a combination of incubation experiments with a 15 N isotope dilution technique were employed, aiming to quantify N mineralization and immobilization processes in surface sediments (0–5 cm) of three types of aquaculture ecosystems (seabass, white shrimp, and green crab ponds) reclaimed within the western bank of the Pearl River Estuary. Our results showed that no significant difference in sediment N mineralization and immobilization rates, microbial abundances, and organic matter among different aquaculture types on small-scale range. Meanwhile, prolonged pond-drying significant reduced sediment N mineralization and immobilization rates, bacterial abundances, organic matter, moisture content, ferrous ion (Fe 2+ ), Fe 2+ /Fe 3+ , and ammonium (NH 4 + ), while not strongly altered sediment percentage of NH 4 + mineralized per day (PAM), relative ammonium immobilization (RAI), fungal abundances, TOC/TN, nitrate (NO 3 − ), and δ 13 C org . N mineralization and immobilization rates were both significantly related to overlying water NO 3 − , as well as sediment moisture content, bulk density, organic matter, Fe 2+ , and microbial abundances. In addition, the total mineralized and immobilized N in aquaculture surface sediments from the Guangdong-Hong Kong-Macao Greater Bay Area were estimated to be approximately 4.55×10 4 and 3.68×10 4 t N yr -1 , respectively. Higher N mineralization relative to N immobilized fluxes indicated that the sediment serves as an important source of eutrophication in reclaimed aquaculture system of coastal wetlands.

The tiered transaction system for sea use rights in China: Theoretical basis and market construction - Xuan Yu; Sen Lin; Weiteng Shen; Qi Chen (Marine Policy, 2023)

Identification of high-concern organic pollutants in tap waters from the Yangtze River in China based on combined screening strategies - Liben Chou; Chengzhuo Zhou; Wenrui Luo; Jing Guo; Yanhong Shen; Die Lin; Chang Wang; Hongxia Yu; Xiaowei Zhang; Si Wei; Wei Shi (Science of The Total Environment, 2023)

High PCBs mineralization capability of a resuscitated strain Bacillus sp. LS1 and its survival in PCB-contaminated soil - Zhen Han; Qihua Lin; Shusheng Zhang; Xinru Zhou; Si Li; Faqian Sun; Chaofeng Shen; Xiaomei Su (Science of The Total Environment, 2023)

Efficient oil-water emulsion treatment via novel composite membranes fabricated by CaCO3-based biomineralization and TA-Ti(IV) coating strategy - Hongli Xie; Binghong Chen; Hongjun Lin; Renjie Li; Liguo Shen; Genying Yu; Lining Yang (Science of The Total Environment, 2023)

Coupling of the ecosystems in North China with the East Asian summer monsoon rainfall during the Holocene - Jiaju Zhao; Jianbao Liu; Jinzhao Liu; Shengqian Chen; Li Wang; Aifeng Zhou; Zhiping Zhang; Zhongwei Shen; Jie Chen; Lin Chen; Yunning Cao; Jing Hu; et al. (Quaternary Science Reviews, 2023)

Rational design of ordered porous nanoparticles for selective extraction of nitrobenzene compounds - Sheng Peng; Minhui Shen; Xiang Li; Yuan-Jun Tong; Jing Guo; Wei Lin; Yu-Xin Ye; Jianqiao Xu; Ningbo Zhou; Fang Zhu; Gangfeng Ouyang (Journal of Hazardous Materials, 2023)

New insights into lincomycin biodegradation by Conexibacter sp. LD01: Genomics characterization, biodegradation kinetics and pathways - Huaxin Lei; Jiayu Zhang; Jin Huang; Dengjin Shen; Yin Li; Rui Jiao; Renxin Zhao; Xiaoyan Li; Lin Lin; Bing Li (Journal of Hazardous Materials, 2023)

Source appointment at large-scale and ungauged catchment using physically-based model and dynamic export coefficient - Wenzhuo Wang; Lei Chen; Chen Lin; Yong Liu; Xin Dong; Junfeng Xiong; Guowangcheng Liu; Yuhan Zhang; Jiaqi Li; Zhenyao Shen (Journal of Environmental Management, 2023)

Quantifying the direct effects of long-term dynamic land use intensity on vegetation change and its interacted effects with economic development and climate change in jiangsu, China - Feixue Shen; Lin Yang; Lei Zhang; Mao Guo; Haili Huang; Chenghu Zhou (Journal of Environmental Management, 2023)

Improved physicochemical stability and bioaccessibility of astaxanthin-loaded oil-in-water emulsions by a casein-caffeic acid–glucose ternary conjugate - Jingrong Cheng; Shuangwei Shen; Huaigu Yang; Daobang Tang; Xuping Wang; Yaosheng Lin; Xueming Liu (Food Research International, 2023)

Enhancement of lycopene bioaccessibility in tomatoes using excipient emulsions: Effect of dark tea polysaccharides - Chao Wang; Yinxin Fu; Yi Cao; Jialu Huang; Hongyi Lin; Peiyi Shen; David Julian McClements; Lingyu Han; Tiantian Zhao; Xiaoxuan Yan; Qian Li (Food Research International, 2023)

Improving probiotic (Lactobacillus casei) viability by encapsulation in alginate-based microgels: Impact of polymeric and colloidal fillers - Qian Li; Hongyi Lin; Jing Li; Lu Liu; Jialu Huang; Yi Cao; Tiantian Zhao; David Julian McClements; Jun Chen; Chengmei Liu; Jiyan Liu; Peiyi Shen; et al. (Food Hydrocolloids, 2023)

The association of long-term ambient fine particulate matter exposure with blood pressure among Chinese adults - Zhennan Lin; Shufeng Chen; Fangchao Liu; Jianxin Li; Jie Cao; Keyong Huang; Fengchao Liang; Jichun Chen; Hongfan Li; Jianfeng Huang; Dongsheng Hu; Chong Shen; et al. (Environmental Pollution, 2023)

Disinfection byproducts formation from emerging organic micropollutants during chlorine-based disinfection processes - Binbin Shao; Leyuan Shen; Zhifeng Liu; Lin Tang; Xiaofei Tan; Dongbo Wang; Weimin Zeng; Ting Wu; Yuan Pan; Xiansheng Zhang; Lin Ge; Miao He (Chemical Engineering Journal, 2023)

Corrigendum to “Novel diketopyrrolopyrrole NIR-II fluorophores and DDR inhibitors for in vivo Chemo-photodynamic therapy of Osteosarcoma” [Chem. Eng. J. 446 (2022) 136929] - Xiaoding Cheng; Chong Zhang; Kun Shen; Huifan Liu; Caihong Bai; Qihang Ding; Mengting Guan; Junzhu Wu; Zhiquan Tian; Deliang Chen; Lin Cai; Xuechuan Hong; et al. (Chemical Engineering Journal, 2023)

N-type small molecule electron transport materials with D-A-D conjugated core for non-fullerene organic solar cells - Dan Zhou; Yubing Li; Hehui Zhang; Haolan Zheng; Xingxing Shen; Wen You; Lin Hu; Liangjing Han; Yongfen Tong; Lie Chen (Chemical Engineering Journal, 2023)

Alleviating the self-discharge and enhancing the polysulphides conversion kinetics with LaCO3OH nanocrystals decorated hierarchical porous carbon - Yuhang Lin; Weiqiang Tang; Siyu Wu; Yongzheng Zhang; Zhenkai Kong; Chunyin Shen; Yanli Wang; Liang Zhan; Licheng Ling (Chemical Engineering Journal, 2023)

The coupling of persulfate activation and membrane separation for the effective pollutant degradation and membrane fouling alleviation - Mingzhu Zhou; Junjie Chen; Shuning Yu; Binghong Chen; Cheng Chen; Liguo Shen; Bisheng Li; Hongjun Lin (Chemical Engineering Journal, 2023)

Black phosphorus nanosheets suppress oxidative damage of stem cells for improved neurological recovery - Fumei He; Zeqi Liu; Jian Xu; Yue Xiong; Xiaopei Zhang; Junyang Qi; Xun Lin; Chengjun Chu; Lan Shen; Gan Liu; Wenbin Deng (Chemical Engineering Journal, 2023)

Nanocellulose interface enhanced all-cellulose foam with controllable strength via a facile liquid phase exchange route - Longfei Sun; Lin Liu; Mingbang Wu; Dengfeng Wang; Rongsheng Shen; Hanfei Zhao; Jing Lu; Juming Yao (Carbohydrate Polymers, 2023)

Study on the Coal–rock Ratio Effect of Asymmetric Deformation and Failure of the Gob–side Coal–rock Roadway in Gently Inclined Coal Seam - Lin Gao; Yexing Shen; Ping Liu; Yongyin Wang; Zhenqian Ma; Xiangtao Kang; Sen Han (Geotechnical and Geological Engineering, 2023)

Establishment of a Ca(II) ion-quantum dots fluorescence signal amplification sensor for high-sensitivity biomarker detection - Yanbing Lv; Panpan Wang; Jinjie Li; Ning Li; Dangdang Xu; Ruili Wu; Huaibin Shen; Lin Song Li (Analytica Chimica Acta, 2023)

Systematic assessment of GPM IMERG V06 precipitation products with dense rain gauge observations over Zhejiang Province, China - Zaoying Bi; Shanlei Sun; Huayu Shen; Yi Liu; Yongjian Ren; Jinjian Li; Bin Lin (International Journal of Climatology, 2022)
This study systematically assessed the performance of the Integrated Multi‐satellitE Retrievals (IMERG) for Global Precipitation Measurement V06, including the near‐real‐time “Late Run” (IMERG‐L) and the post‐real‐time “Final Run” (IMERG‐F), over Zhejiang Province (ZJP), China. The evaluation was conducted at daily and hourly timescales for a full year and for each season, based on dense rain gauge observations and continuous and categorical validation statistics. For the full year and for each season, IMERG‐F outperformed IMERG‐L in representing the spatial pattern of multiyear mean precipitation. For regional mean of ZJP, IMERG‐F and IMERG‐L overestimated the daily/hourly precipitation for the full year by 6.51 and 4.98%, respectively. Among seasons, the regional mean relative biases for IMERG‐F were between 5.65 and 8.63%; however, for IMERG‐L, they exhibited notable variations with a maximum of 11.09% in fall and a minimum of 0 in spring. Bias composition suggested that the regional mean overestimations were largely due to false bias for the full year and for each season, except in winter, wherein it was due to hit bias. Spatially, the biases for the full year and for each season commonly arose from false and hit biases at daily timescale, and from false and miss biases at hourly timescale. Based on the remaining continuous metrics (i.e., root‐mean‐square‐error [RMSE], correlation coefficient [CC], and Kling–Gupta Efficiency [KGE]) and all categorical metrics, the IMERG daily/hourly performance was acceptable on regional and grid scales throughout the year and in all seasons. From a region‐average perspective, IMERG‐F outperformed IMERG‐L according to CC, RMSE, and KGE, but both products showed the same performance overall based on all categorical metrics; most grids also share these characteristics. This study provides a valuable reference for IMERG developers to improve product accuracy from the perspective of the final postprocessing step and for potential users in ZJP.

Effects of exposure to phthalate during early pregnancy on gestational diabetes mellitus: a nested case–control study with propensity score matching - Wei Chen; Caidie He; Xiang Liu; Songlin An; Xia Wang; Lin Tao; Haonan Zhang; Yingkuan Tian; Nian Wu; Pei Xu; Dengqing Liao; Juan Liao; et al. (Environmental Science and Pollution Research, 2022)

Fine-mapping and candidate gene analysis of qFL-c10-1 controlling fiber length in upland cotton (Gossypium hirsutum L.) - Ruiting Zhang; Chao Shen; De Zhu; Yu Le; Nian Wang; Yuanxue Li; Xianlong Zhang; Zhongxu Lin (Theoretical and Applied Genetics, 2022)

Quantitative assessment of fibrosis-4 score and adverse clinical outcomes in patients with COVID-19 - Kefu Tang; Lu Wang; Lu Shen; Lin He; Xi Wu (Science China Life Sciences, 2022)

Elastoplastic Modelling of Porous Limestones with Porosity Dependency - B. Han; Q. M. Gong; X. L. Du; Y. Gao; W. Q. Shen; S. Lin (Rock Mechanics and Rock Engineering, 2022)

Trace Element Changes in the Plasma of Autism Spectrum Disorder Children and the Positive Correlation Between Chromium and Vanadium - Jun Zhang; Jing Lin; Xiying Zhao; Fang Yao; Chengyun Feng; Zhijun He; Xueshan Cao; Yan Gao; Naseer Ullah Khan; Margy Chen; Peng Luo; Liming Shen (Biological Trace Element Research, 2022)

Taxonomy and phylogeny of Pseudovorticella ciliates (Ciliophora, Peritrichia): Two new and one rare species from the coastal waters of China - Yong Zhang; Ying Yu; Zhishuai Qu; Mengmeng Jiang; Zhuo Shen; Jiqiu Li; Xiaofeng Lin (Frontiers in Marine Science, 2022)
Peritrich ciliates are a species-rich group of sessile unicellular eukaryotes, which can be found in various aquatic habitats from all over the world. It is well accepted that there are still many ciliates to be uncovered. During a survey on ciliate biodiversity in the coastal waters of China, three solitary peritrich species were identified as members of the genus Pseudovorticella Foissner & Schiffmann, 1975, including two new species and a rare one. Pseudovorticella zhejiangensis sp. n. differs from its congeners mainly by having a conical-shaped zooid, conspicuous pellicular blisters, one ventral and one dorsal contractile vacuoles, and an infundibular polykinety 3 with three rows of nearly equal length but different beginning positions. Pseudovorticella dalianensis sp. n. can be defined mainly by an obovoid-shaped zooid, one ventral contractile vacuole, and a three-rowed infundibular polykinety 3 with the middle row being the longest. The rare species, Pseudovorticella verrucosa (Dons, 1915) Sun et al., 2009, was redescribed. The small subunit (SSU) rDNA sequences of these three species were sequenced for the first time, the phylogeny of Pseudovorticella species was analyzed, and the results verified the non-monophyly of this genus. This study demonstrates that the morphologic and gene barcoding data are the optimum combination to disclose the biodiversity of ciliates.

A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer - Chang Gong; Ziliang Cheng; Yaping Yang; Jun Shen; Yingying Zhu; Li Ling; Wanyi Lin; Zhigang Yu; Zhihua Li; Weige Tan; Chushan Zheng; Wenbo Zheng; et al. (Science China Life Sciences, 2022)

Associations of metal profiles in blood with thyroiditis: a cross-sectional study - Yaosheng Luo; Huixian Zeng; Yanshi Ye; Genfeng Yu; Cheng Song; Siyang Liu; Xingying Chen; Yuqi Jiang; Hualin Duan; Yue Li; Shengqing He; Zhi Chen; et al. (Environmental Science and Pollution Research, 2022)
Autoimmune thyroiditis (AIT) is increasingly common, and serological markers include thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb). To determine if selected metals influence thyroiditis antibody positivity, this cross-sectional study investigated associations between metals and thyroiditis antibody status. Healthy individuals ( n = 1104) completed a questionnaire and underwent checkups of anthropometric parameters, thyroid function status, and levels of seven metals in blood (magnesium, iron, calcium, copper, zinc, manganese, and lead). Associated profiles of glyco- and lipid metabolism were also established. Logistic regression and restricted cubic spline (RCS) regression analysis were applied to adjudge associations between metals and TPOAb and TgAb status. It was found that, after adjusting for likely cofounding factors, participants with antibody positivity had significantly lower serum concentrations of magnesium and iron. When serum magnesium levels were analyzed in quartiles, the odds ratios of quartile 4 were 0.329–fold (95% confidence interval (CI): 0.167–0647) and 0.259-fold (95% CI 0.177–0.574) that of quartile 1 regarding TPOAb and TgAb positivity ( P = 0.004, 0.003). After adjustment, the RCS analysis detected nonlinear associations between iron and TPOAb and TgAb positivity ( P < 0.01, both). In stratified analyses, these associations regarding magnesium and iron remained for women of reproductive age, but not for postmenopausal women and men. We conclude that lower serum levels of magnesium and iron are associated with incremental positivity of thyroiditis antibodies and may be among the most important metals contributing to AIT in women of reproductive age.

Two new physalins from Physalis alkekengi L. var. franchetii (Mast.) Makino - Jia-Min Sun; Ji-Xiang He; Min Huang; Hui-Xin Hu; Lin-Tao Xu; Kai-Li Fang; Xiao-Ning Wang; Tao Shen (Natural Product Research, 2022)

Calcium Homeostasis in Parkinson’s Disease: From Pathology to Treatment - Jingxian Zhang; Qingqing Shen; Yue Ma; Lin Liu; Wenting Jia; Leilei Chen; Junxia Xie (Neuroscience Bulletin, 2022)

Predicting Lumbar Vertebral Osteopenia Using LvOPI Scores and Logistic Regression Models in an Exploratory Study of Premenopausal Taiwanese Women - Chun-Wen Chen; Yi-Jui Liu; Shao-Chieh Lin; Chien-Yuan Wang; Wu-Chung Shen; Der-Yang Cho; Tung-Yang Lee; Cheng-Hsuan Juan; Cheng-En Juan; Kai-Yuan Cheng; Chun-Jung Juan (Journal of Medical and Biological Engineering, 2022)
Purpose To propose hybrid predicting models integrating clinical and magnetic resonance imaging (MRI) features to diagnose lumbar vertebral osteopenia (LvOPI) in premenopausal women. Methods This prospective study enrolled 101 Taiwanese women, including 53 before and 48 women after menopause. Clinical information, including age, body height, body weight and body mass index (BMI), were recorded. Bone mineral density (BMD) was measured by the dual-energy X-ray absorptiometry. Lumbar vertebral fat fraction (LvFF) was measured by MRI. LvOPI scores (LvOPISs) comprising different clinical features and LvFF were constructed to diagnose LvOPI. Statistical analyses included normality tests, linear regression analyses, logistic regression analyses, group comparisons, and diagnostic performance. A P value less than 0.05 was considered as statistically significant. Results The post-menopausal women had higher age, body weight, BMI, LvFF and lower BMD than the pre-menopausal women (all P < 0.05). The lumbar vertebral osteoporosis group had significantly higher age, longer MMI, and higher LvFF than the LvOPI group (all P < 0.05) and normal group (all P < 0.005). LvOPISs (AUC, 0.843 to 0.864) outperformed body weight (0.747; P = 0.0566), BMI (0.737; P < 0.05), age (0.649; P < 0.05), and body height (0.5; P < 0.05) in diagnosing LvOPI in the premenopausal women. Hybrid predicting models using logistic regression analysis (0.894 to 0.9) further outperformed all single predictors in diagnosing LvOPI in the premenopausal women ( P < 0.05). Conclusion The diagnostic accuracy of the LvOPI can be improved by using our proposed hybrid predicting models in Taiwanese premenopausal women.

Integrated analysis of the transcriptome and metabolome in young and mature leaves of Yunnanopilia longistaminea - Yuchang Wang; Bingqi Shen; Lin Yang; Dawei Wang (Plant Biotechnology Reports, 2022)

Intensity, frequency and rate of insect herbivory for an alpine Rhododendron shrub: elevational patterns and leaf-age effects - Guangshuai Cui; Lin Zhang; Wei Shen; Ying Guo; Eryuan Liang (Alpine Botany, 2022)

Establishment and characterization of a spinal cord tissue cell line from mandarin fish, Siniperca chuatsi and its susceptibility to several viruses - Jinpeng Gong; Xiaoyi Pan; Lingyun Lin; Yue Zhu; Jiayun Yao; Congxu Wang; Wenlin Yin; Lei Huang; Yihan Liu; Fan Chen; Jinyu Shen (Journal of Fish Diseases, 2022)
In this study, we established and characterized a continuous cell line from the spinal cord tissue of mandarin fish, Siniperca chuatsi and assessed its susceptibility to infectious spleen and kidney necrosis virus (ISKNV), Siniperca chuatsi ranavirus (SCRaV) and Siniperca chuatsi rhabdovirus (SCRV). The cell line, named SCC, has been successively cultured up to 40 passages. The optimal growing conditions of SCC cells were in Leibovitz's L‐15 medium supplemented with 20% foetal bovine serum (FBS) at 28°C. Karyotype analysis demonstrated 48 normal diploid chromosomes in the cells. The identity of S. chuatsi origin of SCC cells was confirmed by partial sequencing of the 16S rRNA and cytochrome oxidase I ( COI ) genes. Infection susceptibility assessment showed that ISKNV, SCRIV and SCRV and can be stably produced and transmitted in SCC cells, and the replication efficiency of ISKNV, SCRaV and SCRV ranged from 10 7.4 to 10 9.6 TCID 50 /ml. In addition, transmission electron microscopy analysis of ISKNV, SCRAV and SCRV infected SCC cells showed numerous viral particles. In conclusion, the newly established SCC cells provide an important tool for isolation and production of viruses, as well as for molecular and cell biology studies.

Boundary Layer Features of One Winter Fog in the Yangtze River Delta, China - Peifeng Shen; Duanyang Liu; Ismail Gultep; Huijuan Lin; Ninghao Cai; Shuya Cao; Zida Wang (Pure and Applied Geophysics, 2022)

The Chinese species of skipper butterflies in the tribe Tagiadini Mabille, 1878 (Lepidoptera: Hesperiidae): insights from phylogeny, hostplants, and biogeography - Li Shen; Jianqing Zhu; Yuxiang Lin; Jie Fang; Yongqiang Wang; Liying Tang; Qinghao Zhao; Mengqi Xiao; Feiyu Duan; Qunxiu Liu; Weidong Yu; Weibin Jiang (Organisms Diversity & Evolution, 2022)

Activation of Dopamine D2 Receptors Alleviates Neuronal Hyperexcitability in the Lateral Entorhinal Cortex via Inhibition of HCN Current in a Rat Model of Chronic Inflammatory Pain - Shi-Hao Gao; Yong Tao; Yang Zhu; Hao Huang; Lin-Lin Shen; Chang-Yue Gao (Neuroscience Bulletin, 2022)

Icariin protects bone marrow mesenchymal stem cells in aplastic anemia by targeting MAPK pathway - Shu Deng; Yuqing Zeng; Jingjing Xiang; Shengyun Lin; Jianping Shen (Molecular Biology Reports, 2022)

Cluster analysis of the domain of microseismic event attributes for floor water inrush warning in the working face - Guo-Jun Shang; Xiao-Fei Liu; Li Li; Li-Song Zhao; Jin-Song Shen; Wei-Lin Huang (Applied Geophysics, 2022)

Ancylostoma ceylanicum Infection in a Miniature Schnauzer Dog Breed - Xu-Hui Lin; Hai-Ming Cai; Zhuan-Qiang Yan; Shen-Quan Liao; Min-Na Lv; Cai-Yan Wu; Juan Li; Jun-Jing Hu; Wen-Wan Xiao; Jian-Fei Zhang; Nan-Shan Qi; Ming-Fei Sun (Acta Parasitologica, 2022)

Metabolomics analysis of the potential toxicological mechanisms of diquat dibromide herbicide in adult zebrafish (Danio rerio) liver - Ye Xiao; Xiang Lin; Meilan Zhou; Tianyu Ren; Ruili Gao; Zhongqun Liu; Wenjing Shen; Rong Wang; Xi Xie; Yanting Song; Wenting Hu (Fish Physiology and Biochemistry, 2022)

Identification of a Novel Species, Cladonema digitatum sp. nov. (Cnidaria: Hydrozoa: Cladonematidae), Using DNA Barcoding and Life Cycle Analyses - Xinyu Fang; Shen Lin; Yuting Zhang; Zonghua Wang; Konglin Zhou; Jianming Chen (Frontiers in Marine Science, 2022)
In this study, a new Cladonema species was identified in a laboratory aquarium in Fuzhou, China, and named Cladonema digitatum sp. nov. based on its morphological characteristics and DNA barcoding. It is distinct from other Cladonema medusae in having a manubrium with finger-like protuberances, radial canals with Y-shaped bifurcations, tentacles with 3–11 adhesive branches, and 3–7 stinging branches growing from the main branch as side branches. The validity of C. digitatum sp. nov. was supported by molecular phylogenetic analyses based on both mitochondrial cytochrome oxidase and mitochondrial 16S rRNA sequences. Similar to other Cladonema medusae, the adhesive and stinging branches of each tentacle, oral tentacle, manubrium, and gonads in C. digitatum displayed considerable phenotypic plasticity, thus making species identification based solely on morphology difficult. Although diagnostic characters such as filiform tentacles and medusa buds of hydroids and nematocysts are also useful for species identification in the genus Cladonema , related information is missing in some Cladonema species. Thus, information on the life cycle and DNA barcoding should be updated to describe new or cryptic species and to improve the taxonomy of the genus Cladonema .

Statistical study on the CSES radio occultation data and its quality control in electron density inversion - Shengfeng Gu; Chengkun Gan; Yun Qing; Jian Lin; Xiaomin Luo; Xuhui Shen; Jingnan Liu (GPS Solutions, 2022)

H3K4me3 CUT&Tag and Transcriptome Analysis Reveal the Epigenetic Regulatory Landscape in Gill Tissue of Large Yellow Croaker (Larimichthys crocea) Under Low Salinity Stress - Jian Yang; Minhai Liu; Weiliang Shen; Tingting Zhou; Xiongfei Wu; Qi Li; Zhihua Lin (Frontiers in Marine Science, 2022)
H3K4me3 is an important histone modification that could influence DNA replication and RNA translation in response to abiotic stress. Here, RNA-seq analyses were conducted in gill tissues of large yellow croaker to identify the function of H3K4me3 under low salinity stress. Additionally, CUT&Tag analyses were performed to identify the genome-wide dynamic changes in H3K4me3 and explore the mechanisms by which H3K4me3 regulates gene expression. A total of 201 differentially expressed genes (DEGs) were identified between the 5‰ low salinity group (S-group) and 25‰ normal salinity group (C-group), among which 23 DEGs (11 up-regulated H3K4me3 targets and 12 down-regulated targets) were directly regulated by H3K4me3. Our findings thus describe the epigenetic regulatory landscape of H3K4me3 in gill of large yellow croaker during low salinity stress, and provide novel insights into the regulation mechanisms of H3K4me3 mediating the responses of aquatic animals to abiotic stress.

Evaluation and Temporal-Spatial Deconstruction for High-Quality Development of Regional Marine Economy: A Case Study of China - Dong An; Chunlei Shen; Lin Yang (Frontiers in Marine Science, 2022)
The high-quality development of the marine economy has become a realistic choice to stimulate the vitality of regional economic growth and achieve the goal of building a powerful nation in the marine economy. This study constructs an evaluation index system from efficiency, coordination, innovation, sustainability, openness, and shareability to analyze the high-quality development level and temporal-spatial heterogeneity of China’s regional marine economy from 2010 to 2018. Methods used in this paper are entropy, kernel density estimation, and partial spatial autocorrelation analysis. The results are shown as follows: (1) The high-quality development level of China’s regional marine economy shows a slow fluctuating and upward trend, coordination, sustainability, and innovation are the primary driving forces. The ranking of the three marine economic circles in the development quality of the marine economy is Eastern> Southern>Northern, the ranking of coastal provinces is Guangdong> Shanghai> Shandong> Zhejiang> Fujian> Tianjin> Jiangsu> Liaoning> Hainan> Hebei> Guangxi. The primary driving forces for Guangdong, Shanghai, Shandong, and Zhejiang leading other coastal areas are openness, efficiency, innovation, and sustainability respectively; (2) the temporal differentiation of China’s regional marine economy shows a dynamic evolution process that is obvious in the early stages, alleviating in the middle stage, and balance in the later stage; (3) the spatial zoning types and high-quality development paths of 11 coastal provinces are determined based on spatial differentiation: Shanghai and Zhejiang are high-value congregate types and named as demonstration regions, which should build global marine center cities with deepening regional cooperation and high-standard opening-up; Shandong and Guangdong are high-value discrete types and named as key engine regions, which should enhance the international competitiveness of the marine industry with scientific and technological innovation; Tianjin, Hebei, and Liaoning are low-value congregate types and named as potential zooming regions, which should improve the efficiency of marine resources utilization with regional cooperation; Jiangsu, Fujian, Hainan, and Guangxi are low-value discrete types and named as land-sea coordination regions, which should build a modern and characteristic marine industrial system coordinated with land and sea.

Numerical Study of Effective Thermal Conductivity for Periodic Closed-Cell Porous Media - Yu-Lin Shen; Mohammad G. Abdo; Isabella J. Van Rooyen (Transport in Porous Media, 2022)

A Deep Mesencephalic Nucleus Circuit Regulates Licking Behavior - Di Zheng; Jia-Yu Fu; Meng-Yu Tang; Xiao-Dan Yu; Yi Zhu; Chen-Jie Shen; Chun-Yue Li; Shi-Ze Xie; Shan Lin; Minmin Luo; Xiao-Ming Li (Neuroscience Bulletin, 2022)

Bedside Diagnosis for Disseminated Deep Dermatophytosis: a Case Series Study - Xiu-Jiao Xia; Hong Shen; Hui-Lin Zhi; Yan Zhong; Bo Sang; Wen-Wen Lv; Qiu-Ping Li; Ze-Hu Liu (Mycopathologia, 2022)

Emerging role of exosomal long non-coding RNAs in lung cancer - Lulu He; Minmin Lin; Jing Shen; Hongyan Qi (Molecular Biology Reports, 2022)

A Combined Proteomics and Metabolomics Profiling to Investigate the Genetic Heterogeneity of Autistic Children - Liming Shen; Huajie Zhang; Jing Lin; Yan Gao; Margy Chen; Naseer Ullah Khan; Xiaoxiao Tang; Qi Hong; Chengyun Feng; Yuxi Zhao; Xueshan Cao (Molecular Neurobiology, 2022)

Ubiquitin specific peptidase 47 promotes proliferation of lung squamous cell carcinoma - Lin Yu; Jiayu Fu; Chunjian Shen (Genes & Genomics, 2022)

Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model - Wan-yi Li; Jun-yan Gao; Su-Yang Lin; Shao-tao Pan; Biao Xiao; Yu-tao Ma; Kai Xie; Wei Shen; Zhi-tao Liu; Guang-yu Li; Jie-jie Guo; Qin-wen Wang; et al. (Molecular Neurobiology, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

Multifunctional Role of Silica in Pharmaceutical Formulations - Yating Gao; Yue Zhang; Yanlong Hong; Fei Wu; Lan Shen; Youjie Wang; Xiao Lin (AAPS PharmSciTech, 2022)

Baculoviruses hijack the visual perception of their caterpillar hosts to induce climbing behaviour thus promoting virus dispersal - Xiaoming Liu; Zhiqiang Tian; Limei Cai; Zhongjian Shen; J. P. Michaud; Lin Zhu; Shuo Yan; Vera I. D. Ros; Kelli Hoover; Zhen Li; Songdou Zhang; Xiaoxia Liu (Molecular Ecology, 2022)
Baculoviruses can induce climbing behaviour in their caterpillar hosts to ensure they die at elevated positions to enhance virus transmission, providing an excellent model to study parasitic manipulation of host behaviour. Here, we demonstrate that climbing behaviour occurred mostly during daylight hours, and that the height at death of Helicoverpa armigera single nucleopolyhedrovirus (HearNPV)‐infected larvae increases with the height of the light source. Phototaxic and electroretinogram (ERG) responses were enhanced after HearNPV‐infection in host larvae, and ablation of stemmata in infected larvae prevented both phototaxis and climbing behaviour. Through transcriptome and quantitative PCR, we confirmed that two opsin genes (a blue light‐sensitive gene, HaBL ; and a long wave‐sensitive gene, HaLW ) as well as the TRPL (transient receptor potential‐like channel protein) gene, all integral to the host's visual perception pathway, were significantly upregulated after HearNPV infection. Knockout of HaBL , HaLW , or TRPL genes using the CRISPR/Cas9 system resulted in significantly reduced ERG responses, phototaxis, and climbing behaviour in HearNPV‐infected larvae. These results reveal that HearNPV alters the expression of specific genes to hijack host visual perception at fundamental levels—photoreception and phototransduction—in order to induce climbing behaviour in host larvae.

Quadratic Stress Drop Model of the 2013 Mw 6.6 Lushan Earthquake and Aftershocks Triggered by Blind Thrust Events - Qiu Zhong; Jian Lin; Baoping Shi; Wenhao Shen (Pure and Applied Geophysics, 2022)

Crocin Alleviates Intracerebral Hemorrhage–Induced Neuronal Ferroptosis by Facilitating Nrf2 Nuclear Translocation - Fei Wang; Wu-lin Li; Li-juan Shen; Ting-ting Jiang; Jian-jun Xia; Da-li You; Shan-you Hu; Li Wang; Xiao Wu (Neurotoxicity Research, 2022)

Follicular Fluid-Derived Exosomal MicroRNA-18b-5p Regulates PTEN-Mediated PI3K/Akt/mTOR Signaling Pathway to Inhibit Polycystic Ovary Syndrome Development - Zhi Zhou; Zhihua Tu; Juan Zhang; Can tan; Xiaoyong Shen; Bangbei Wan; Yejuan Li; Anguo Wang; Liqiang Zhao; Jiajia Hu; Ning Ma; Jing Zhou; et al. (Molecular Neurobiology, 2022)

TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury - Yao Lin; Tingting Huang; Weimin Shen; Qiongyi Pang; Qingfeng Xie; Xiang Chen; Fengxia Tu (Journal of Molecular Neuroscience, 2022)

Sterols and triterpenoids from Ganoderma lucidum and their reversal activities of tumor multidrug resistance - Min Wu; Cui-e Shen; Qiao-fa Lin; Jin-yi Zhong; Yan-fei Zhou; Ben-chen Liu; Jian-hua Xu; Zhi-qiang Zhang; Peng Li (Natural Product Research, 2022)

Low-cost Imaging of Fluorescent DNA in Agarose Gel Electrophoresis using Raspberry Pi cameras - Hassan Ali Abid; Jian Wern Ong; Eric Shen Lin; Zhixiong Song; Oi Wah Liew; Tuck Wah Ng (Journal of Fluorescence, 2022)
Low-cost analytical solutions built around microcomputers like the Raspberry Pi help to facilitate laboratory investigations in resource limited venues. Here, three camera modules (V1.3 with and without filter, as well as NoIR) that work with this microcomputer were assessed for their suitability in imaging fluorescent DNA following agarose gel electrophoresis. Evaluation of their utility was based on signal-to-noise (SNR) and noise variance metrics that were developed. Experiments conducted with samples were subjected to Polymerase Chain Reaction (PCR), and the amplified products were separated using gel electrophoresis and stained with Midori green. Image analysis revealed the NoIR camera performed the best with SNR and noise variance values of 21.7 and 0.222 respectively. In experiments conducted using UV LED lighting to simulate ethidium bromide (EtBr) excitation, the NoIR and V1.3 with filter removed cameras showed comparable SNR values.

Sphingobacterium bovistauri sp. nov., Isolated from the Faeces of Bos Taurus - Qiong Wang; Zhi-Qin Fang; Chen-Lu Zhang; Jian-Qiang Shen; Jian-Dong Lai; Xiu-Lin Han; Tao Lu (Current Microbiology, 2022)

Fishery Dynamics, Status, and Rebuilding Based on Catch-Only Data in Coastal Waters of China - Linlong Wang; Li Lin; Yang Liu; Lu Zhai; Shen Ye (Frontiers in Marine Science, 2022)
China has become the largest contributor to marine fisheries in the world with its fishing fleets explosively increasing their fishing effort and resulting catch, but its fishery composition and sustainability have deteriorated. Limited information on fishery exploitation status encumbers effective resource management. In this study, a data-poor Monte Carlo method, the Catch-Maximum Sustainable Yield (CMSY) method, was used to estimate the historical exploited dynamics and current stock status of ten Chinese economic marine fish stocks, including Trichiurus lepturus , Larimichthys crocea , Larimichthys polyactis , Thamnaconus modestus , Scomberomorus niphonius , Ilisha elongate , Decapterus maruadsi , Scomber japonicus , Engraulis japonicus , and Clupea pallasii , which accounted for about 50% of total fish catches in the coastal waters of China and covered five functional groups (i.e., large, medium benthopelagic, large, medium, and small pelagic). Species L. crocea and L. polyactis had been subjected to overfishing since the 1950s. The others showed a decreasing trend in biomass along with the explosively increasing fishing efforts since the 1990s. Benthopelagic fish experienced overfishing pressure about a decade earlier than pelagic species. All the fish stocks investigated in this study were depleted (current biomass lower than the biomass capable of producing maximum sustainable yields, i.e., B < B msy ) in 2019, and most species were still facing high-fishing pressure (current fishing mortality higher than the mortality capable of producing maximum sustainable yields, i.e., F > F msy ). Also, a Schaefer model was used to assess stocks rebuilding status until 2030 under four exploitation scenarios, i.e., fishing mortality equals 0.5, 0.6, 0.8, or 0.95 times F msy . Most species stocks will likely recover to the B msy , which indicates that reduction of fishing pressure is probably the most effective way for fishery recovery.

Socioeconomic Patterns for Global Mangrove Cover Changes with Multi-Database Analyses - Ruihan Lin; Shen Yu; Bing Hong (Wetlands, 2022)

The genesis of Guanting Pb–Zn deposits in the Jianshui area, Yunnan Province, SW China: Constraints from geochronology, S isotopes and trace elements - Xiaoli Shen; Honghong Lin; Baolin Zhang; Qingxiang Du (Mineralogy and Petrology, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Changes in the growth performance, antioxidant enzymes and stress resistance caused by dietary administration of synbiotic (fructooligosaccharide and probiotics) in juvenile Chinese Mitten Crab, Eriocheir sinensis - Jin-Juan Wan; Jian-lin Pan; Mei-Fang Shen; Hui Xue; Meng-lin Sun; Mei-Qin Zhang; Xi-He Zhu; Xing-kong Ma (Aquaculture International, 2022)

Mesozoic mafic dykes in the North China Craton: magmatic evolution and implications for gold mineralization - Chao Li; Lin Li; Sheng-Rong Li; M. Santosh; Jun-Feng Shen (International Geology Review, 2022)

A new abietane-type diterpenoid and a new long-chain alkenone from fungus Daldinia sp. TJ403-LS1 - Shuang Lin; Xueke Zhang; Ling Shen; Shuyuan Mo; Junjun Liu; Jianping Wang; Zhengxi Hu; Yonghui Zhang (Natural Product Research, 2022)

Highly selective monoclonal antibody-based lateral flow immunoassay for visual and sensitive determination of conazole fungicides propiconazole in vegetables - Ze-Ke Xu; Jing-Nan Meng; Yi Lei; Xing-Xing Yang; Yi-Yong Yan; Hai-Hong Liu; Hong-Tao Lei; Ting-Cai Wang; Xing Shen; Zhen-Lin Xu (Food Additives & Contaminants: Part A, 2022)

Bioactive hydroxypropionylated glucose derivatives from Astragalus bhotanensis - Lin Qiu; Chao-Jiang Xiao; Yi Shen; Wei Xu; Xiao-Bo Liu; Xiang Dong; Bei Jiang (Natural Product Research, 2021)

The Effects of Limosilactobacillus reuteri LR-99 Supplementation on Body Mass Index, Social Communication, Fine Motor Function, and Gut Microbiome Composition in Individuals with Prader–Willi Syndrome: a Randomized Double-Blinded Placebo-Controlled Trial - Xue-Jun Kong; Kevin Liu; Patrick Zhuang; Ruiyi Tian; Siyu Liu; Cullen Clairmont; Xiaojing Lin; Hannah Sherman; Junli Zhu; Yelan Wang; Michelle Fong; Alice Li; et al. (Probiotics and Antimicrobial Proteins, 2021)
Prader–Willi syndrome (PWS) is a rare genetic disorder associated with developmental delay, obesity, and neuropsychiatric comorbidities. Limosilactobacillus reuteri ( Lactobacillus reuteri , Lact. reuteri ) has demonstrated anti-obesity and anti-inflammatory effects in previous studies. In the present study, we aim to evaluate the effects of Lact. reuteri supplementation on body mass index (BMI), social behaviors, and gut microbiota in individuals with PWS. We conducted a 12-week, randomized, double-blind, placebo-controlled trial in 71 individuals with PWS aged 6 to 264 months (64.4 ± 51.0 months). Participants were randomly assigned to either receive daily Lact. reuteri LR-99 probiotic (6 × 10 10 colony forming units) or a placebo sachet. Groupwise differences were assessed for BMI, ASQ-3, and GARS-3 at baseline, 6 weeks, and 12 weeks into treatment. Gut microbiome data was analyzed with the QIIME2 software package, and predictive functional profiling was conducted with PICRUSt-2. We found a significant reduction in BMI for the probiotic group at both 6 weeks and 12 weeks relative to the baseline ( P < 0.05). Furthermore, we observed a significant improvement in social communication and interaction, fine motor function, and total ASQ-3 score in the probiotics group compared to the placebo group ( P < 0.05). Altered gut microbiota was observed in the probiotic group to favor weight loss and improve gut health. The findings suggest a novel therapeutic potential for Lact. reuteri LR-99 probiotic to modulate BMI, social behaviors, and gut microbiota in Prader–Willi syndrome patients, although further investigation is warranted. Trial registration Chinese Clinical Trial Registry: ChiCTR1900022646

Realization of Natural Human Motion on a 3D Biped Robot For Studying the Exoskeleton Effective - Chi-Ying Lee; Shih Chieh Lan; Jung-Ji Lin; Yu-Ting Lin; Po-Shen Chiang; Wei-Li Hsu; Kuo-Kuang Jen; Andy Y. S. Huang; Jia-Yush Yen (Journal of Medical and Biological Engineering, 2021)

Efficiency and mechanism of a vermicompost additive in enhancing composting of swine manure - Xiaoxia Hao; Xinyuan Ma; Bo Zeng; Li Zhu; Linyuan Shen; Mingxian Yang; Hongwen Hu; Dongmei Jiang; Lin Bai (Environmental Science and Pollution Research, 2021)

Persistent pollution episodes, transport pathways, and potential sources of air pollution during the heating season of 2016–2017 in Lanzhou, China - Yongtao Guo; Chunying Lin; Jiangping Li; Lingbo Wei; Yuxia Ma; Qidong Yang; Dandan Li; Hang Wang; Jiahui Shen (Environmental Monitoring and Assessment, 2021)

Development and characterization of SNP markers in many-lined sun skink (Eutropis multifasciata) from transcriptomic sequences - Youfu Lin; Zijin Qian; Shiyu Shen; Yicheng Huang; Yu Du; Hong Li; Lian Chen (Conservation Genetics Resources, 2021)

Rapid visual genotyping method for germline mutants with small genomic fragment deletion by allele-specific PCR and lateral flow nucleic acid biosensor - Qiuju Su; Xiang Zhou; Tianwen Wu; Kui Li; Wentao Xu; Zhenyu Lin; Ping Shen; Bang Liu (Molecular Biology Reports, 2021)

Spatial distributions and risk assessments of nutrients and heavy metalsin sediments from an impounded lake of China’s South-to-NorthWater Diversion Project - Baoying Wang; Jianyu Lin; Xiaogang Wu; Yinian Xue; Chao Han; Zhihong Zhang; Jinghua Ren; Qiushi Shen (Environmental Science and Pollution Research, 2021)

Strategies of cadmium and copper uptake and translocation in different plant species growing near an E-waste dismantling site at Wenling, China - Jiao Jiao Li; Xue Qiang Zhao; Jia Lin Wang; Ren Fang Shen (Environmental Science and Pollution Research, 2021)

The role of mechanical harvesting on the recession of aquatic vegetation under an extreme water level increase in a eutrophic shallow lake - Changtao Yang; Jing Nan; Jianhua Li; Yi Lin; Jie Yu; Jianbin Wu; Xiaobing Shen (Environmental Science and Pollution Research, 2021)

Dynamics Simulation of Grasping Process of Underwater Vehicle-Manipulator System - Zongyu Chang; Yang Zhang; Zhongqiang Zheng; Lin Zhao; Kunfan Shen (Journal of Marine Science and Engineering, 2021)
Underwater vehicle-manipulator system (UVMS) can be applied to fulfill different complex underwater tasks such as grasping, drilling, sampling, etc. It is widely used in the field of oceanographic research, marine exploration, military, and commercial applications. In this paper, the dynamic simulation of UVMS is presented in the process of grasping an object. First, the dynamic model of UVMS, which considers the change of the load of manipulator when the end effector of manipulator grasps the object, is developed. To compare different conditions, numerical simulation of grasping processes without/with vehicle attitude control are carried out. The simulation results show that the coupling dynamics between the vehicle and the manipulator in the grasping process are clearly illustrated. It deteriorates the positioning accuracy of the end effector of the manipulator and is harmful to underwater precision operations. The tracking position error of end effector without vehicle control is large and UVMS cannot complete the grasping task under this condition. Vehicle control can compensate the motion of the vehicle due to the coupling effect caused by the motion of the manipulator. This study will contribute to underwater operation mission for UVMS with floating base.

Correction to: Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering - Ya Tang; Jialiang Tian; Long Li; Lin Huang; Quan Shen; Shanzhu Guo; Yue Jiang (Tissue Engineering and Regenerative Medicine, 2021)

Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering - Ya Tang; Jialiang Tian; Long Li; Lin Huang; Quan Shen; Shanzhu Guo; Yue Jiang (Tissue Engineering and Regenerative Medicine, 2021)

Depression Augments Plasma APOA4 without Changes of Plasma Lipids and Glucose in Female Adolescents Carrying G Allele of APOA4 rs5104 - Qi Wei Guo; Yan Jun Si; Yi Lin Shen; Xu Chen; Mei Yang; Ding Zhi Fang; Jia Lin (Journal of Molecular Neuroscience, 2021)

Anti-miR33 therapy improved hepatopancreatic lipid and immune metabolism disorders in grass carp, Ctenopharyngodon idella - Rong-Hua Lu; Meng-Jun Lin; Feng Yang; Shen-zong Jia; Yu-Ru Zhang; Chao-Bin Qin; Xiao-Lin Meng; Guo-Xing Nie (Fish Physiology and Biochemistry, 2021)

Ambient climate determines the directional trend of community stability under warming and grazing - Peipei Liu; Wangwang Lv; Jianping Sun; Caiyun Luo; Zhenhua Zhang; Xiaoxue Zhu; Xingwu Lin; Jichuang Duan; Guangping Xu; Xiaofeng Chang; Yigang Hu; Qiaoyan Lin; et al. (Global Change Biology, 2021)
Changes in ecological processes over time in ambient treatments are often larger than the responses to manipulative treatments in climate change experiments. However, the impacts of human‐driven environmental changes on the stability of natural grasslands have been typically assessed by comparing differences between manipulative plots and reference plots. Little is known about whether or how ambient climate regulates the effects of manipulative treatments and their underlying mechanisms. We collected two datasets, one a 36‐year long‐term observational dataset from 1983 to 2018, and the other a 10‐year manipulative asymmetric warming and grazing experiment using infrared heaters with moderate grazing from 2006 to 2015 in an alpine meadow on the Tibetan Plateau. The 36‐year observational dataset shows that there was a nonlinear response of community stability to ambient temperature with a positive relationship between them due to an increase in ambient temperature in the first 25 years and then a decrease in ambient temperature thereafter. Warming and grazing decreased community stability with experiment duration through an increase in legume cover and a decrease in species asynchrony, which was due to the decreasing background temperature through time during the 10‐year experiment period. Moreover, the temperature sensitivity of community stability was higher under the ambient treatment than under the manipulative treatments. Therefore, our results suggested that ambient climate may control the directional trend of community stability while manipulative treatments may determine the temperature sensitivity of the response of community stability to climate relative to the ambient treatment. Our study emphasizes the importance of the context dependency of the response of community stability to human‐driven environmental changes.

Antifungal weapons of Lysobacter , a mighty biocontrol agent - Long Lin; Kangwen Xu; Danyu Shen; Shan‐Ho Chou; Mark Gomelsky; Guoliang Qian (Environmental Microbiology, 2021)
Summary Bacteria interact with fungi in a variety of ways to inhibit fungal growth, while the underlying mechanisms remain only partially characterized. The plant‐beneficial Bacillus and Pseudomonas species are well‐known antifungal biocontrol agents, whereas Lysobacter are far less studied. Members of Lysobacter are easy to grow in fermenters and are safe to humans, animals and plants. These environmentally ubiquitous bacteria use a diverse arsenal of weapons to prey on other microorganisms, including fungi and oomycetes. The small molecular toxins secreted by Lysobacter represent long‐range weapons effective against filamentous fungi. The secreted hydrolytic enzymes act as intermediate‐range weapons against non‐filamentous fungi. The contact‐dependent killing devices are proposed to work as short‐range weapons. We describe here the structure, biosynthetic pathway, action mode and applications of one of the best‐characterized long‐range weapons, the heat‐stable antifungal factor (HSAF) produced by Lysobacter enzymogenes . We discuss how the flagellar type III secretion system has evolved into an enzyme secretion machine for the intermediate‐range antifungal weapons. We highlight an intricate mechanism coordinating the production of the long‐range weapon, HSAF and the proposed contact‐dependent killing device, type VI secretion system. We also overview the regulatory mechanisms of HSAF production involving specific transcription factors and the bacterial second messenger c‐di‐GMP.

In silico design of antimicrobial oligopeptides based on 3D-QSAR modeling and bioassay evaluation - Guangping Li; Yuxuan Wang; Yan Shen; Haiqiong Guo; Qingxiu He; Yong Hu; Haibin Liu; Zhihua Lin; Yuanqiang Wang (Medicinal Chemistry Research, 2021)

Plant multiscale networks: charting plant connectivity by multi-level analysis and imaging techniques - Xi Zhang; Yi Man; Xiaohong Zhuang; Jinbo Shen; Yi Zhang; Yaning Cui; Meng Yu; Jingjing Xing; Guangchao Wang; Na Lian; Zijian Hu; Lingyu Ma; et al. (Science China Life Sciences, 2021)

Climate change impacts on China’s marine ecosystems - Bin Kang; Gretta T. Pecl; Longshan Lin; Peng Sun; Peidong Zhang; Yuan Li; Linlin Zhao; Xin Peng; Yunrong Yan; Chunyan Shen; Wentao Niu (Reviews in Fish Biology and Fisheries, 2021)

The preference of maize plants for nitrate improves fertilizer N recovery efficiency in an acid soil partially because of alleviated Al toxicity - Jia Lin Wang; Xue Qiang Zhao; Hao Qing Zhang; Ren Fang Shen (Journal of Soils and Sediments, 2021)

Effect of Quicklime on Microbial Community in Strong Acidic Soil - Junwei Liang; Xiangquan Yu; Yafan Cao; Jiguang Zhang; Ning Yan; Lin Xue; Xianjie Cai; Guoming Shen (Journal of Soil Science and Plant Nutrition, 2021)

Differential DNA Methylation Profiles in Patients with Temporal Lobe Epilepsy and Hippocampal Sclerosis ILAE Type I - Wang Zhang; Haiyang Wang; Binchao Liu; Miaomiao Jiang; Yifei Gu; Shi Yan; Xian Han; Alicia Y. Hou; Chongyang Tang; Zhenfeng Jiang; Hong Shen; Meng Na; et al. (Journal of Molecular Neuroscience, 2021)

Profiling heterogenous sizes of circulating tumor microemboli to track therapeutic resistance and prognosis in advanced gastric cancer - Yang Chen; Jiajia Yuan; Yanyan Li; Xue Li; Ying Yang; Jian Li; Yilin Li; Lin Shen (Human Cell, 2021)
Circulating tumor microemboli (CTM) aggregated by ≥ 2 circulating tumor cells (CTCs) are more migratory than single CTCs. Aside from the plasticity in their molecular characteristics, which have been considered tumor migration, CTM also possesses high size heterogeneity. This study, therefore, systematically investigated the heterogeneous sizes of CTM and their involvement in therapeutic resistance in 114 patients with advanced gastric cancer (GC) using a pre-established surface molecule-independent subtraction enrichment (SE)-iFISH strategy. CTM, which was pre-therapeutically detected in 33.3% of GC patients, can further form in another 34.78% of patients following chemo-/targeted therapies. The presence of CTM is relevant to liver metastasis as well as higher CTC levels (≥ 5/6 mL). Further size-based profiling of GC-CTM revealed that CTM with 2 CTCs (CTM 2 ) was the dominant subtype, accounting for 50.0% of all detected GC-CTMs. However, CTM with 3–4 CTCs (CTM 3–4 ) specifically associates with chemo-/targeted therapeutic resistance and inferior prognosis. Patients with ≥ 1 CTM 3–4 /6 mL have shorter median progression-free survival and median overall survival. Unlike CTM 2 and CTM 3–4 , which are detectable in pre-therapy and post-therapy, larger aggregated CTM ≥5 (CTM with ≥ 5 CTCs) was only intra-therapeutically detected in four HER2 + GC patients, of which three experienced liver metastases. Obtained results suggested that the cluster size of GC-CTM should be dynamically profiled beyond pre-therapeutic whole CTM enumeration in terms of chemo-/targeted resistance or metastasis monitoring. GC-CTM 3–4 could be a potential indicator of therapeutic resistance, while the dynamic presence of GC-CTM ≥5 implies liver metastasis in HER2 + GC patients.

Antimicrobial Activity of Natural Plant Compound Carvacrol Against Soft Rot Disease Agent Dickeya zeae - Shangbo Jiang; Jingxin Zhang; Qiyun Yang; Dayuan Sun; Xiaoming Pu; Huifang Shen; Qiqin Li; Zhongwen Wang; Birun Lin (Current Microbiology, 2021)

Sphingobacterium rhinopitheci sp. Nov., isolated from the faeces of Rhinopithecus bieti in China - Xiu-Lin Han; Qiong Wang; Chen-Lu Zhang; Zhi-Qin Fang; Jian-Qiang Shen; Song Huang; Tao Lu (Archives of Microbiology, 2021)

Synergistic impacts of nutrient enrichment and climate change on long‐term water quality and ecological dynamics in contrasting shallow‐lake zones - Qi Lin; Ke Zhang; Suzanne McGowan; Eric Capo; Ji Shen (Limnology and Oceanography, 2021)
Anthropogenic and climatic stressors on freshwater ecosystems are of global concern. However, the interactions and effects of multiple stressors (e.g., nutrient enrichment, climate warming, altered wind and precipitation) acting over different spatial and temporal scales are often complex and remain controversial. Here, we reconstructed one‐century dynamics of eutrophication and primary producer communities in algal‐dominated and macrophyte‐dominated zones of a large shallow lake (Taihu, China), by integrating sedimentary photosynthetic pigments and geochemical records with water monitoring and historical archives. We aimed to explore the long‐term underlying mechanisms of the responses of water quality and lake biota to multiple environmental perturbations. We found that water quality degradation and algal community modification showed similar trends but distinct timings and trajectories in contrasting ecological zones. Onset and intensity of eutrophication in north Meiliang Bay (since the 1950s) exceeded far beyond that of macrophyte‐dominated Eastern Taihu (~1990s). Anthropogenic nutrients overtook past climatic control on production and composition of phototrophic assemblages. More importantly, lake phytoplankton responded markedly to climate warming, decreasing wind speed, and extreme weathers after cultural eutrophication. Synergistic interactions of nutrients and climate on lake ecosystems became increasingly significant in promoting harmful algal blooms (HABs) dominated by Microcystis , close to the hyper‐eutrophic north lake zones. The asynchronous limnological and ecological responses also indicated the modulating roles of lake ecological regime and catchment hydrogeomorphic characteristic. Collectively, our findings suggest that mitigation of eutrophication and HABs calls for a triple management strategy integrating anthropogenic nutrients, climate change, and lake‐catchment setting.

Genome-wide association mapping for agronomic traits in an 8-way Upland cotton MAGIC population by SLAF-seq - Cong Huang; Chao Shen; Tianwang Wen; Bin Gao; De Zhu; Dingguo Li; Zhongxu Lin (Theoretical and Applied Genetics, 2021)

Proteomics provides individualized options of precision medicine for patients with gastric cancer - Wenwen Huang; Dongdong Zhan; Yazhuo Li; Nairen Zheng; Xin Wei; Bin Bai; Kecheng Zhang; Mingwei Liu; Xuefei Zhao; Xiaotian Ni; Xia Xia; Jinwen Shi; et al. (Science China Life Sciences, 2021)

Associations of Sleep Characteristics with Cerebrospinal Fluid sTREM2 in Cognitively Normal Older Adults: the CABLE Study - He-Ying Hu; Ling-Zhi Ma; Hao Hu; Yan-Lin Bi; Ya-Hui Ma; Xue-Ning Shen; Ya-Nan Ou; Qiang Dong; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

Exploring the environmental and economic potential for biogas production from swine manure wastewater by life cycle assessment - Meng-Fen Shih; Chyi-How Lay; Chiu-Yue Lin; Shen-Ho Chang (Clean Technologies and Environmental Policy, 2021)

Nonlinearity of Subtidal Estuarine Circulation in the Pearl River Estuary, China - Hongzhou Xu; Jian Shen; Dongxiao Wang; Lin Luo; Bo Hong (Frontiers in Marine Science, 2021)
The Pearl River Estuary (PRE) is a bell-shaped estuary with a narrow deep channel and wide shoals. This unique topographic feature leads to different dynamics of the subtidal estuarine circulation (SEC) in the PRE compared with a narrow and straight estuary. In this study, the nonlinear dynamics of the SEC in the PRE under mean circumstance are analyzed by using a validated 3D numerical model. Model results show that the nonlinear advections reach leading order in the along-channel momentum balance. Modulated by tide, the nonlinear advections show significant temporal variations as they have much larger values during spring tide than that during neap tide. Unlike straight and narrow estuaries, both tidally and cross-sectionally averaged axial and lateral advections play important roles in driving the SEC in the PRE in which the axial advection dominates the nonlinear effect, but the two nonlinear terms balance each other largely resulting in a reduced nonlinear effect. Despite this, the total nonlinear advection is still comparable with other terms, and it acts as the baroclinic pressure to reinforce the SEC, especially during the ebb tide, suggesting a flood–ebb asymmetry of the nonlinear dynamics in the PRE. In addition, diagnostic analyses of the along-channel vorticity budget show that nonlinear advections also make significant contribution to drive the lateral circulation in the PRE as Coriolis and baroclinic pressure terms, indicating complex dynamics of the circulation in the PRE.

Microbial deterioration and restoration in greenhouse-based intensive vegetable production systems - Weishou Shen; Mingcheng Hu; Dong Qian; Huaiwen Xue; Nan Gao; Xiangui Lin (Plant and Soil, 2021)

Sleep Characteristics and Cerebrospinal Fluid Progranulin in Older Adults: The CABLE Study - Meng Wang; Fu-Rong Sun; Yan-Lin Bi; Ya-Hui Ma; Jian-Jun Yin; Xue-Ning Shen; Xiao-Tong Wang; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

A dye combination for the staining of pollen coat and pollen wall - Xin-Lei Jia; Jing-Shi Xue; Fang Zhang; Chi Yao; Shi-Yi Shen; Chang-Xu Sui; Yu-Jia Peng; Qin-Lin Xu; Yi-Feng Feng; Wen-Jing Hu; Ping Xu; Zhong-Nan Yang (Plant Reproduction, 2021)

Provenance of the Late Cretaceous sediments in Jiaolai Basin, Eastern China, and its tectonic implications - Bo Zhang; Shaofeng Liu; Chengfa Lin; Yu Wang; Zhehan Wang; Min Fang; Wenjie Shen (International Geology Review, 2021)

Complete genome analysis of a divergent isolate of narcissus yellow stripe virus from China - Xihong Chen; Shuangqing Lin; Jianguo Shen; Furong Liao; Shouling Chen; Fangluan Gao (Journal of Plant Pathology, 2021)