Molecular diversity of methanotrophs in Transbaikal soda lake sediments and identification of potentially active populations by stable isotope probing - Ju‐Ling Lin; Stefan Radajewski; Bulat T. Eshinimaev; Yuri A. Trotsenko; Ian R. McDonald; J Colin Murrell (Environmental Microbiology, 2004)
Summary Soda lakes are an environment with an unusually high pH and often high salinity. To identify the active methanotrophs in the Soda lake sediments, sediment slurries were incubated with a 10% (v/v) 13 CH 4 headspace and the 13 C‐labelled DNA was subsequently extracted from these sediments following CsCl density gradient centrifugation. This DNA was then used as a template for PCR amplification of 16S rRNA genes and genes encoding PmoA and MmoX of methane monooxygenase, key enzymes in the methane oxidation pathway. Phylogenetic analysis of 16S rRNA genes, PmoA and MmoX identified that strains of Methylomicrobium , Methylobacter , Methylomonas and ‘Methylothermus’ had assimilated the 13 CH 4 . Phylogenetic analysis of PmoA sequences amplified from DNA extracted from Soda lake sediments before Stable Isotope Probing (SIP) treatment showed that a much wider diversity of both type I and type II methanotroph sequences are present in this alkaline environment. The majority of methanotroph sequences detected in the 13 C‐DNA studies were from type I methanotrophs, with 50% of 16S rRNA clones and 100% of pmoA clones from both Lake Suduntuiskii Torom and Lake Gorbunka suggesting that the type I methanotrophs are probably responsible for the majority of methane oxidation in this environment.

Effect of fenofibrate on LDL-induced endothelial dysfunction in rats - Tian-Lun Yang; Mei-Fang Chen; Bai-Ling Luo; Jing Yu; Jun-Lin Jiang; Yuan-Jian Li (Naunyn-Schmiedeberg's Archives of Pharmacology, 2004)

Inhibitory effect of resveratrol on angiotensin II-induced cardiomyocyte hypertrophy - Tzu-Hurng Cheng; Ju-Chi Liu; Heng Lin; Neng-Lang Shih; Yen-Ling Chen; Meng-Ting Huang; Paul Chan; Ching-Feng Cheng; Jin-Jer Chen (Naunyn-Schmiedeberg's Archives of Pharmacology, 2004)

Diverse apoptotic pathways in enterovirus 71–infected cells - Shih-Cheng Chang; Jing-Yi Lin; Lily Yen-Cheng Lo; Mei-Ling Li; Shin-Ru Shih (Journal of NeuroVirology, 2004)

Identification of genes involved in the host response to enterovirus 71 infection - Shin-Ru Shih; Victor Stollar; Jing-Yi Lin; Shih-Cheng Chang; Guang-Wu Chen; Mei-Ling Li (Journal of NeuroVirology, 2004)

Sequence Analysis of the Complete Genome of Rice Black-Streaked Dwarf Virus Isolated from Maize with Rough Dwarf Disease - Zhao-Hui Wang; Shou-Guo Fang; Jia-Ling Xu; Li-Ying Sun; Da-Wei Li; Jia-Lin Yu (Virus Genes, 2003)

Postglacial population growth of Cunninghamia konishii (Cupressaceae) inferred from phylogeographical and mismatch analysis of chloroplast DNA variation - Shih‐Ying Hwang; Tsan‐Piao Lin; Chiu‐Shun Ma; Chung‐Ling Lin; Jeng‐Der Chung; Jenq‐Chuan Yang (Molecular Ecology, 2003)
Phylogeographical and mismatch analysis of chloroplast DNA (cpDNA) variation were used to infer the temporal dynamics of distributional and demographic history of Taiwan fir ( Cunninghamia konishii ). We examined 64 and 52 trees from 17 populations of C. konishii and 14 provenances of C. lanceolata , respectively, by sequencing three intergenic spacers and one intron using cpDNA universal primers. Of the aligned 1888 base pairs (bp) sequence, 30 varied among 28 haplotypes, which consisted of three transitions, 14 transversions and 13 indels. One ancestral haplotype was found in 86 individuals across the surveyed range of both species, C. konishii and C. lanceolata , which was distributed in all populations and provenances. The 28 haplotypes also included 15 C. konishii specific and 12 C. lanceolata ‐specific haplotypes. Ancestral haplotype was found fixed in five populations of C. konishii and five provenances of C. lanceolata . Other haplotypes occurred mainly as singletons. The levels of population differentiation studied are relatively low in both Cunninghamia species. The nucleotide diversity ( θ ) of chloroplast DNA sequences within C. konishii was slightly higher than that of C. lanceolata . Excess in singletons as well as star‐like phylogeny of haplotypes suggested no clearcut migration patterns of C. konishii after glacial maximum. One probable demographic history of C. konishii is the postglacial population growth of C. konishii after a glacial bottleneck event. This inference is supported by the combined results of fossil pollen record, low nucleotide diversity, significant Tajima's d ‐value, phylogeographical analysis and unimodal mismatch distribution. Similarities and discrepancies between our results and those of Lu et al. (2001) are discussed.

The blockade of formyl peptide-induced respiratory burst by 2',5'-dihydroxy-2-furfurylchalcone involves phospholipase D signaling in neutrophils - Jih-Pyang Wang; Ling-Chu Chang; Mei-Feng Hsu; Chun-Nan Lin (Naunyn-Schmiedeberg's Archives of Pharmacology, 2003)

Overexpression, Purification, and Characterization of the Recombinant Leucine Aminopeptidase II of Bacillus stearothermophilus - Lih-Ying Kuo; Guang-Yuh Hwang; Yu-Jing Lai; Shin-Ling Yang; Long-Liu Lin (Current Microbiology, 2003)

Propofol reduces nitric oxide biosynthesis in lipopolysaccharide-activated macrophages by downregulating the expression of inducible nitric oxide synthase - Ruei-Ming Chen; Gong-Jhe Wu; Yi-Ting Tai; Wei-Zen Sun; Yi-Ling Lin; Wen-Chi Jean; Ta-Liang Chen (Archives of Toxicology, 2003)

The anabolic pyruvate oxidoreductase from Methanococcus maripaludis - Winston C. Lin; Yu-Ling Yang; William B. Whitman (Archives of Microbiology, 2003)

Activin stimulates goldfish FSH biosynthesis by enhancing FSHβ promoter activity - Wei Ge; Nga-Ling Ko; Flora Yee-Man Pang; Me-Fong Chung; Sze-Wah Lin; Chi-Wai Yuen; Man-Tat Lau; Lin Liu; Young Chang Sohn; Makito Kobayashi; Katsumi Aida (Fish Physiology and Biochemistry, 2003)

Inhibition of return in children with attention deficit hyperactivity disorder - Chiang-Shan Ray Li; Hsueh-Ling Chang; Shih-Chieh Lin (Experimental Brain Research, 2003)

EXPRESSION OF SECRETED FRIZZLED-RELATED PROTEIN 2 IN A PRIMARY CANINE MAMMARY TUMOR CELL LINE: A CANDIDATE TUMOR MARKER FOR MAMMARY TUMOR CELLS - JIA-LIN LEE; CHING-JIN CHANG; LING-LING CHUEH; CHUNG-TIEN LIN (In Vitro Cellular & Developmental Biology - Animal, 2003)

EXPRESSION OF SECRETED FRIZZLED RELATED PROTEIN 2 IN A PRIMARY CANINE MAMMARY TUMOR CELL LINE: A CANDIDATE TUMOR MARKER FOR MAMMARY TUMOR CELLS - Jia-Lin Lee; Ching-Jin Chang; Ling-Ling Chueh; Chung-Tien Lin (In Vitro Cellular & Developmental Biology - Animal, 2003)

Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients - Ying-Hwa Chen; Shing-Jong Lin; Ming-Wei Lin; Hui-Ling Tsai; San-San Kuo; Jaw-Wen Chen; Min-Ji Charng; Tao-Cheng Wu; Lung-Ching Chen; Philip Ding; Wen-Harn Pan; Yuh-Shan Jou; et al. (Human Genetics, 2002)

Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1 - Yen-Chou Chen; Shing-Chuan Shen; Woan-Rouh Lee; Hui-Yi Lin; Ching-Huai Ko; Chun-Ming Shih; Ling-Ling Yang (Archives of Toxicology, 2002)

Calyculin A Sensitive Protein Phosphatase Is Required for Bacillus anthracis Lethal Toxin Induced Cytotoxicity - Jyh-Hwa Kau; Ching-Gong Lin; Hsin-Hsien Huang; Hui-Ling Hsu; Kuo-Ching Chen; Yu-Ping Wu; Hung-Chi Lin (Current Microbiology, 2002)

Early genes responsive to abscisic acid during heterophyllous induction in Marsilea quadrifolia - Ting-Chang Hsu; Hung-Chi Liu; Jang-Shiun Wang; Rung-Wu Chen; Ying-Chuan Wang; Bai-Ling Lin (Plant Molecular Biology, 2001)

Design of environmental decision support system and its application to water quality management - Zeng Fan-tang; Du Ling; Lin Kui; Shen Qian (Journal of Geographical Sciences, 2001)

A simple method to determine urea concentration using intact Helicobacter pylori and BromoCresol Purple as a pH indicator - Yuh-Ling Lin; Chien-Tsu Chen; Su-Cheng Lin; Cheng Lee; Hsien-Shou Kuo; Chun-Mean Shih; Yuan-Hsun Hsu; Yi-Ping Chin; Err-Cheng Chan (Biotechnology Letters, 2000)

Contributory presentations/posters - N. Manoj; V. R. Srinivas; A. Surolia; M. Vijayan; K. Suguna; R. Ravishankar; K. Suguna; A. Surolia; M. Vijayan; R. Schwarzenbacher; K. Zeth; Diederichs; et al. (Journal of Biosciences, 1999)

Effects of recombinant lysostaphin on cytotoxicity and interleukin-8 level in normal human epidermal keratinocytes cell line - Err-Cheng Chan; C. Allen Chang; Tzong-Zeng Wu; Yuh-Ling Lin (Biotechnology Letters, 1998)

Characterization of 12 microsatellite loci of the human MHC in a panel of reference cell lines - Maureen P. Martin; Anita Harding; Robert Chadwwick; Mel Kronick; Michael Cullen; Ling Lin; Emmanuel Mignot; M. Carrington (Immunogenetics, 1998)

Characterization of 12 microsatellite loci of the human MHC in a panel of reference cell lines - Maureen P. Martin; Anita Harding; Robert Chadwick; Mel Kronick; Michael Cullen; Ling Lin; Emmanuel Mignot; M. Carrington (Immunogenetics, 1997)

Sequence-based association analysis of HLA class I and II alleles in Japanese supports conservation of common haplotypes - K. Tokunaga; Yoshihide Ishikawa; Atsuko Ogawa; Huiru Wang; Shigeki Mitsunaga; Satoshi Moriyama; Ling Lin; Makoto Bannai; Yoshihisa Watanabe; Kouichi Kashiwase; Hidenori Tanaka; Tatsuya Akaza; et al. (Immunogenetics, 1997)