Numerical Studies of Polymer Materials with Potential for Use in Coronary Stent-Grafts - K. Yu. Klyshnikov; M. A. Rezvova; T. V. Glushkova; Yu. A. Kudryavtseva; E. A. Ovcharenko (Biomedical Engineering, 2022)

Global maps of soil temperature - Jonas J. Lembrechts; Johan van den Hoogen; Juha Aalto; Michael B. Ashcroft; Pieter De Frenne; Julia Kemppinen; Martin Kopecký; Miska Luoto; Ilya M. D. Maclean; Thomas W. Crowther; Joseph J. Bailey; Stef Haesen; et al. (Global Change Biology, 2022)
Research in global change ecology relies heavily on global climatic grids derived from estimates of air temperature in open areas at around 2 m above the ground. These climatic grids do not reflect conditions below vegetation canopies and near the ground surface, where critical ecosystem functions occur and most terrestrial species reside. Here, we provide global maps of soil temperature and bioclimatic variables at a 1‐km 2 resolution for 0–5 and 5–15 cm soil depth. These maps were created by calculating the difference (i.e. offset) between in situ soil temperature measurements, based on time series from over 1200 1‐km 2 pixels (summarized from 8519 unique temperature sensors) across all the world's major terrestrial biomes, and coarse‐grained air temperature estimates from ERA5‐Land (an atmospheric reanalysis by the European Centre for Medium‐Range Weather Forecasts). We show that mean annual soil temperature differs markedly from the corresponding gridded air temperature, by up to 10°C (mean = 3.0 ± 2.1°C), with substantial variation across biomes and seasons. Over the year, soils in cold and/or dry biomes are substantially warmer (+3.6 ± 2.3°C) than gridded air temperature, whereas soils in warm and humid environments are on average slightly cooler (−0.7 ± 2.3°C). The observed substantial and biome‐specific offsets emphasize that the projected impacts of climate and climate change on near‐surface biodiversity and ecosystem functioning are inaccurately assessed when air rather than soil temperature is used, especially in cold environments. The global soil‐related bioclimatic variables provided here are an important step forward for any application in ecology and related disciplines. Nevertheless, we highlight the need to fill remaining geographic gaps by collecting more in situ measurements of microclimate conditions to further enhance the spatiotemporal resolution of global soil temperature products for ecological applications.

Demographic composition, not demographic diversity, predicts biomass and turnover across temperate and tropical forests - Jessica F. Needham; Daniel J. Johnson; Kristina J. Anderson‐Teixeira; Norman Bourg; Sarayudh Bunyavejchewin; Nathalie Butt; Min Cao; Dairon Cárdenas; Chia‐Hao Chang‐Yang; Yu‐Yun Chen; George Chuyong; Handanakere S. Dattaraja; et al. (Global Change Biology, 2022)
The growth and survival of individual trees determine the physical structure of a forest with important consequences for forest function. However, given the diversity of tree species and forest biomes, quantifying the multitude of demographic strategies within and across forests and the way that they translate into forest structure and function remains a significant challenge. Here, we quantify the demographic rates of 1961 tree species from temperate and tropical forests and evaluate how demographic diversity (DD) and demographic composition (DC) differ across forests, and how these differences in demography relate to species richness, aboveground biomass (AGB), and carbon residence time. We find wide variation in DD and DC across forest plots, patterns that are not explained by species richness or climate variables alone. There is no evidence that DD has an effect on either AGB or carbon residence time. Rather, the DC of forests, specifically the relative abundance of large statured species, predicted both biomass and carbon residence time. Our results demonstrate the distinct DCs of globally distributed forests, reflecting biogeography, recent history, and current plot conditions. Linking the DC of forests to resilience or vulnerability to climate change, will improve the precision and accuracy of predictions of future forest composition, structure, and function.

Microplastics in Sediment of Kuakata Beach, Bangladesh: Occurrence, Spatial Distribution, and Risk Assessment - Partho Banik; M. Belal Hossain; As-Ad Ujjaman Nur; Tasrina Rabia Choudhury; Samia Islam Liba; Jimmy Yu; Md. Abu Noman; Jun Sun (Frontiers in Marine Science, 2022)
Kuakata beach, known as Daughter of Sea in Bangladesh, has drawn a growing number of tourists from all over the world, leading to the higher use of single plastic products. This study was a first attempt to describe the occurrence, spatial distribution, and ecological risk of microplastics (MPs) in Kuakata beach sediments. A total of 24 surface sediment samples were collected from the intertidal zone of the beach, and MPs were extracted using the density separation method and a stereomicroscope. Fourier transform infrared (FTIR) spectroscopy was used for qualitative and quantitative identification. The results revealed that the average MPs in the beach sediment were 232 ± 52 items kg –1 dry weight, which was much higher than many other sandy beaches throughout the world. Analyses of variance showed a significant ( p < 0.01) difference among the mean abundance of MPs in sampling points. Fibers were dominated in every sampling point with an average of 123 ± 27 item kg –1 . Most of the MPs observed were colored (60%), and the rest were transparent (40%). It was found that the size range of 1–5 mm MPs constituted over half (55%) of total MPs covering an average value of 127 ± 34 items kg –1 . Three polymer types were identified in the sediment samples through FTIR analysis which followed the decreasing order of polyethylene terephthalate > polyethylene > polypropylene. Correlation analysis showed a positive relationship between the abundance of MPs and the finer grain size of sediment ( p = 0.055; r = 0.7), indicating grain size-controlled the density of MPs. The pollution load index was assessed to estimate the ecological risk and found that the beach sediment of Kuakata belonged to the risk category I of the pollution index. This investigation provided preliminary information on MPs pollution in the marine ecosystem that the policymakers can use to take appropriate management approaches.

An overview on plasticized biodegradable corn starch-based films: the physicochemical properties and gelatinization process - Bin Wang; Bin Yu; Chao Yuan; Li Guo; Pengfei Liu; Wei Gao; Dapeng Li; Bo Cui; A. M. Abd El-Aty (Critical Reviews in Food Science and Nutrition, 2022)

Influence of KAR1 on the plant growth and development of dormant seeds by balancing different factors - A. Sami; Z. H. Zhu; T. X. Zhu; D. M. Zhang; L. H. Xiao; Y. Yu; K. J. Zhou (International Journal of Environmental Science and Technology, 2022)

Geographic distribution of racial differences in mortality in muscle-invasive bladder cancer patients: an opportunity for improvement - Elliott Freudenburg; Yong Shan; Ariza Martinez; Aditya Srinivasan; Giri Movva; Alexander Yu; Mohanad AlBayyaa; Zachary Klaassen; Stephen J. Freedland; Ashish M. Kamat; Stephen B. Williams (Cancer Causes & Control, 2022)

Ultrastructure and Morphological Variability of Non-Culturable Forms of Yersinia pseudotuberculosis Bacteria - L. M. Somova; E. I. Drobot; I. N. Lyapun; E. V. Pustovalov; E. V. Matosova; M. Yu. Shchelkanov (Bulletin of Experimental Biology and Medicine, 2022)

Early Diagnostic Markers and Therapeutic Targets for Experimental Breast Cancer - N. N. Ermakova; O. V. Pershina; M. A. Zhukova; A. V. Pakhomova; E. S. Pan; L. A. Sandrikina; V. A. Krupin; O. Yu. Rybalkina; A. M. Dygai; E. G. Skurikhin (Bulletin of Experimental Biology and Medicine, 2022)

Increased Yield of Residual γH2AX Foci in p53-Deficient Human Lung Carcinoma Cells Exposed to Subpicosecond Beams of Accelerated Electrons - N. Yu. Vorobyeva; N. S. Babayan; B. A. Grigoryan; A. A. Sargsyan; L. G. Khondkaryan; L. S. Apresyan; A. K. Chigasova; E. I. Yashkina; D. V. Guryev; S. M. Rodneva; A. A. Tsishnatti; Yu. A. Fedotov; et al. (Bulletin of Experimental Biology and Medicine, 2022)

The Role of JAK and STAT3 in Regulation of Secretory Function of Neuroglial Cells of Different Types in Ethanol-Induced Neurodegenerationt - G. N. Zyuz’kov; V. V. Zhdanov; L. A. Miroshnichenko; T. Yu. Polyakova; E. V. Simanina; M. G. Danilets; M. Yu. Minakova; A. A. Churin; V. I. Agafonov (Bulletin of Experimental Biology and Medicine, 2022)

Effect of Probiotic Therapy on Hemodynamic Response Associated with Systemic Inflammatory Reaction and Antibiotic-Induced Dysbiosis in Chronic Experiments in Rats - Yu. Yu. Borshchev; E. S. Protsak; I. Yu. Burovenko; N. Yu. Semenova; I. G. Zubkov; M. M. Galagudza (Bulletin of Experimental Biology and Medicine, 2022)

Correction to: Allochromatium tepidum, sp. nov., a hot spring species of purple sulfur bacteria - Michael T. Madigan; Jill N. Absher; Joseph E. Mayers; Marie Asao; Deborah O. Jung; Kelly S. Bender; Megan L. Kempher; Mackenzie K. Hayward; Sophia A. Sanguedolce; Abigail C. Brown; Shinichi Takaichi; Ken Kurokawa; et al. (Archives of Microbiology, 2022)

Evaluating the probiotic potential and adhesion characteristics of Bacillus spp. isolated from the intestine of Rhynchocypris lagowskii Dybowski - Yurou Zhang; Zhenchao Wu; Mengnan Yu; Dongming Zhang; Qiuju Wang; Lili Lin; Guiqin Wang; Mahmoud M. Elsadek; Qi Yao; Yuke Chen; Zhixin Guo (Aquaculture International, 2022)

Assessment of the effects of spatiotemporal characteristics of drought on crop yields in southwest China - Ali Mokhtar; Hongming He; Karam Alsafadi; Safwan Mohammed; Olusola O. Ayantobo; Ahmed Elbeltagi; Ossama M. M. Abdelwahab; Hongfei Zhao; Ye Quan; Hazem Ghassan Abdo; Yeboah Gyasi‐Agyei; Yu Li (International Journal of Climatology, 2022)
There are limited literature on the impacts of drought on crop yields in warm regions such as southwest China. Drought vulnerability of four different crops (wheat, rice, maize and sugarcane) cultivated in three provinces (Sichuan, Guizhou and Yunnan) within southwest China were investigated in this study. It was based on the drought index of standardized precipitation evapotranspiration index (SPEI) for ‐3‐ and ‐6 months timescales (SPEI‐3 and SPEI‐6). The correlation between the SPEI and the standardized yield residuals series index for the individual crops was estimated for the period from 1960 to 2018. The highest drought duration was recorded in the southern part of the study area especially in the Yunnan Province. For SPEI‐3, 60% of the total area was affected by drought mainly during the months from August to December for about 13 years (2005–2018). In terms of SPEI‐6, the total affected area by the drought exceeded 80% during the timeframe from 2009 to 2013. Among the studied crops, winter wheat had the highest annual crop yield losses particularly in 2010 when the loss exceeded 50%. The results of this study have implications for agricultural management and climate policymaking in minimizing the influence of drought under the warming climate in southwest China. Further, it provides greater insight into crop–climate interactions and sustainable crop production.

New type of RNA virus replication inhibitor based on decahydro-closo-decaborate anion containing amino acid ester pendant group - Varvara V. Avdeeva; Timur M. Garaev; Natalia V. Breslav; Elena I. Burtseva; Tatyana V. Grebennikova; Andrei P. Zhdanov; Konstantin Yu. Zhizhin; Elena A. Malinina; Nikolay T. Kuznetsov (JBIC Journal of Biological Inorganic Chemistry, 2022)

Safety and Pharmacokinetics of Intranasally Administered Heparin - Hannah M. Harris; Katherine L. Boyet; Hao Liu; Rohini Dwivedi; Nicole M. Ashpole; Ritesh Tandon; Gene L. Bidwell; Zhi Cheng; Lauren A. Fassero; Christian S. Yu; Vitor H. Pomin; Dipanwita Mitra; et al. (Pharmaceutical Research, 2022)

Clinical and Pathopsychological Characteristics of Juvenile Depression with Attenuated Schizophrenic Spectrum Symptoms - M. A. Omelchenko; Yu. A. Atadzhykova; V. V. Migalina; I. Yu. Nikiforova; V. G. Kaleda (Neuroscience and Behavioral Physiology, 2022)

Recapitulating lipid accumulation and related metabolic dysregulation in human liver-derived organoids - Ling Wang; Meng Li; Bingting Yu; Shaojun Shi; Jiaye Liu; Ruyi Zhang; Ibrahim Ayada; Monique M. A. Verstegen; Luc J. W. van der Laan; Maikel P. Peppelenbosch; Wanlu Cao; Qiuwei Pan (Journal of Molecular Medicine, 2022)

Quercetin improves the apoptotic index and oxidative stress in post-thaw dog sperm - Seonggyu Bang; Ahmad Yar Qamar; Bereket Molla Tanga; Xun Fang; Gyeonghwan Seong; Abdelbagi Hamad Talha Nabeel; Il-Jeoung Yu; Islam M. Saadeldin; Jongki Cho (Environmental Science and Pollution Research, 2022)

Landscape REE anomalies and the cause of geophagy in wild animals at kudurs (mineral salt licks) in the Sikhote-Alin (Primorsky Krai, Russia) - A. M. Panichev; N. V. Baranovskaya; I. V. Seryodkin; I. Yu. Chekryzhov; E. A. Vakh; B. R. Soktoev; A. I. Belyanovskaya; R. A. Makarevich; T. N. Lutsenko; N. Yu. Popov; A. V. Ruslan; D. S. Ostapenko; et al. (Environmental Geochemistry and Health, 2022)

Gene expression regulating the cell cycle and gene of antioxidant protection system in toxic hepatitis - Y. V. Valova; M. M. Ziatdinova; G. F. Mukhammadieva; D. O. Karimov; A. S. Fazlyeva; N. Yu. Khusnutdinova; T. G. Yakupova; E. F. Repina (Toxicology and Environmental Health Sciences, 2022)

Interaction of Human Dendritic Cells with Graphene Oxide Nanoparticles In Vitro - S. V. Uzhviyuk; M. S. Bochkova; V. P. Timganova; P. V. Khramtsov; K. Yu. Shardina; M. D. Kropaneva; A. I. Nechaev; M. B. Raev; S. A. Zamorina (Bulletin of Experimental Biology and Medicine, 2022)

Estimation of the Regenerative Potential of para-Tyrosol in the Model of Testicular Insufficiency Caused by Damage to Spermatogonial Stem Cells - T. G. Borovskaya; V. A. Grigor’eva; Yu. A. Shchemerova; S. I. Kamalova; A. V. Vychuzhanina; N. A. Krivova; O. B. Zaeva; V. E. Goldberg; A. M. Dygai (Bulletin of Experimental Biology and Medicine, 2022)

Motion Artefact Reduction in Dual-Energy Radiography - Yu. E. Shunkov; I. S. Kobylkin; A. V. Prokhorov; D. V. Pozdnyakov; D. M. Kasiuk; V. A. Nechaev; O. M. Alekseeva; D. I. Naumova; A. R. Dabagov (Biomedical Engineering, 2022)

A System of Local Analyzers for Noninvasive Diagnostics of the General State of the Tissue Microcirculation System of Human Skin - V. V. Sidorov; Yu. L. Rybakov; V. M. Gukasov; G. S. Evtushenko (Biomedical Engineering, 2022)

The influence of aboveground and belowground species composition on spatial turnover in nutrient pools in alpine grasslands - Xin Jing; Case M. Prager; Litong Chen; Haiyan Chu; Nicholas J. Gotelli; Jin‐Sheng He; Yu Shi; Teng Yang; Biao Zhu; Aimée T. Classen; Nathan J. Sanders (Global Ecology and Biogeography, 2022)
Aim An important research question in ecology is how climate and the biodiversity of aboveground plants and belowground microbiomes affect ecosystem functions such as nutrient pools. However, little is studied on the concurrent role of above‐ and belowground species composition in shaping the spatial distribution patterns of ecosystem functions across environmental gradients. Here, we investigated the relationships between the taxonomic composition of plants, soil bacteria and soil fungi and spatial turnover in nutrient pools, and assessed how species composition–nutrient pool relationships were mediated by contemporary climatic conditions. Location Qinghai‐Tibetan Plateau. Time period Current. Major taxa studied Plants, soil bacteria and soil fungi. Methods We surveyed plant assemblages, sampled the taxonomic composition of soil bacteria and soil fungi, and measured plant‐ and soil‐mediated nutrient pools at 60 alpine grasslands on the Qinghai‐Tibetan Plateau. Using Mantel tests, structural equation models and general linear models, we investigated the relative importance of the taxonomic composition of plant, soil bacterial, and soil fungal communities on the spatial turnover of alpine grassland nutrient pools. Results We found that the taxonomic composition of plant, soil bacterial, and soil fungal communities was associated with local climate. However, the effects of local climate on the spatial turnover of plant‐ and soil‐mediated nutrient pools were mainly indirect and mediated through plant and soil bacterial species composition, but not through soil fungal species composition. We further found that the replacement component of soil bacterial β‐diversity and the richness difference of plant β‐diversity were the direct predictors of nutrient pools in the alpine grasslands. Main conclusions These results highlight that belowground bacterial composition together with aboveground plant species composition are related to spatial turnover in nutrient pools, perhaps even driving it. Conserving above‐ and belowground biodiversity may therefore safeguard against the impacts of local climate on the functions of climate‐sensitive alpine grasslands.

Are we actually measuring growth?—An appeal to use a more comprehensive growth index system for advancing aquaculture research - Zhen‐Yu Du; Giovanni M. Turchini (Reviews in Aquaculture, 2022)

Organochlorine Compounds in Commercial Bivalves from the Mekong and Saigon–Dong Nai River Deltas (South Vietnam) - Maksim M. Donets; Vasiliy Yu. Tsygankov; Alexander V. Polevschikov; Veronika I. Kulshova; Joseph A. Elkhoury; Margarita D. Boyarova; Larisa A. Prozorova; Elena N. Chernova; Victor V. Bogatov; Eugenia V. Lysenko; Ngo Xuan Quang (Water, Air, & Soil Pollution, 2022)

Mechanisms of AMPA Receptor Inhibition by Diminazene - A. S. Zhigulin; M. Yu. Dron; O. I. Barygin (Neuroscience and Behavioral Physiology, 2022)

Structure modification, antialgal, antiplasmodial, and toxic evaluations of a series of new marine-derived 14-membered resorcylic acid lactone derivatives - Wei-Feng Xu; Na-Na Wu; Yan-Wei Wu; Yue-Xuan Qi; Mei-Yan Wei; Laura M. Pineda; Michelle G. Ng; Carmenza Spadafora; Ji-Yong Zheng; Ling Lu; Chang-Yun Wang; Yu-Cheng Gu; et al. (Marine Life Science & Technology, 2022)
Marine natural products play critical roles in the chemical defense of many marine organisms and are essential, reputable sources of successful drug leads. Sixty-seven 14-membered resorcylic acid lactone derivatives 3 – 27 and 30 – 71 of the natural product zeaenol ( 1 ) isolated from the marine-derived fungus Cochliobolus lunatus were semisynthesized by chlorination, acylation, esterification, and acetalization in one to three steps. The structures of these new derivatives were established by HRESIMS and NMR techniques. All the compounds ( 1 – 71 ) were evaluated for their antialgal and antiplasmodial activities. Among them, 14 compounds displayed antifouling activities against adhesion of the fouling diatoms. In particular, 9 and 34 exhibited strong and selective inhibitory effects against the diatoms Navicula laevissima and Navicula exigua (EC 50 = 6.67 and 8.55 μmol/L), respectively, which were similar in efficacy to those of the positive control SeaNine 211 (EC 50 = 2.90 and 9.74 μmol/L). More importantly, 38 , 39 , and 69 – 71 showed potent antiplasmodial activities against Plasmodium falciparum with IC 50 values ranging from 3.54 to 9.72 μmol/L. Very interestingly, the five antiplasmodial derivatives displayed non-toxicity in the cytotoxicity assays and the zebrafish embryos model, thus, representing potential promising antiplasmodial drug agents. The preliminary structure–activity relationships indicated that biphenyl substituent at C-2, acetonide at positions C-5′ and C-6′, and tri- or tetra-substituted of acyl groups increased the antiplasmodial activity. Therefore, combining evaluation of chemical ecology with pharmacological models will be implemented as a systematic strategy, not only for environmentally friendly antifoulants but also for structurally novel drugs.

miR-146a-5p modulates cellular senescence and apoptosis in visceral adipose tissue of long-lived Ames dwarf mice and in cultured pre-adipocytes - Allancer D. C. Nunes; Moritz Weigl; Augusto Schneider; Sarah Noureddine; Lin Yu; Collin Lahde; Tatiana Dandolini Saccon; Kunal Mitra; Esther Beltran; Johannes Grillari; James L. Kirkland; Tamara Tchkonia; et al. (GeroScience, 2022)

New Carbon-Mineral Sorbent Based on Aluminum Oxide, Polydimethylsiloxane, and Single-Wall Carbon Nanotubes: Assessment of the Effect on Erythrocytes In Vitro - V. V. Nimaev; A. V. Pivkina; A. V. Shurlygina; L. N. Rachkovskaya; A. A. Smagin; E. S. Yastrebova; E. E. Rachkovskii; M. A. Korolev; V. P. Mal’tsev; A. Yu. Letyagin (Bulletin of Experimental Biology and Medicine, 2022)

Coupling plant litter quantity to a novel metric for litter quality explains C storage changes in a thawing permafrost peatland - Moira Hough; Samantha McCabe; S. Rose Vining; Emily Pickering Pedersen; Rachel M. Wilson; Ryan Lawrence; Kuang‐Yu Chang; Gil Bohrer; William J. Riley; Patrick M. Crill; Ruth K. Varner; Steven J. Blazewicz; et al. (Global Change Biology, 2022)
Permafrost thaw is a major potential feedback source to climate change as it can drive the increased release of greenhouse gases carbon dioxide (CO 2 ) and methane (CH 4 ). This carbon release from the decomposition of thawing soil organic material can be mitigated by increased net primary productivity (NPP) caused by warming, increasing atmospheric CO 2 , and plant community transition. However, the net effect on C storage also depends on how these plant community changes alter plant litter quantity, quality, and decomposition rates. Predicting decomposition rates based on litter quality remains challenging, but a promising new way forward is to incorporate measures of the energetic favorability to soil microbes of plant biomass decomposition. We asked how the variation in one such measure, the nominal oxidation state of carbon (NOSC), interacts with changing quantities of plant material inputs to influence the net C balance of a thawing permafrost peatland. We found: (1) Plant productivity (NPP) increased post‐thaw, but instead of contributing to increased standing biomass, it increased plant biomass turnover via increased litter inputs to soil; (2) Plant litter thermodynamic favorability (NOSC) and decomposition rate both increased post‐thaw, despite limited changes in bulk C:N ratios; (3) these increases caused the higher NPP to cycle more rapidly through both plants and soil, contributing to higher CO 2 and CH 4 fluxes from decomposition. Thus, the increased C‐storage expected from higher productivity was limited and the high global warming potential of CH 4 contributed a net positive warming effect. Although post‐thaw peatlands are currently C sinks due to high NPP offsetting high CO 2 release, this status is very sensitive to the plant community's litter input rate and quality. Integration of novel bioavailability metrics based on litter chemistry, including NOSC, into studies of ecosystem dynamics, is needed to improve the understanding of controls on arctic C stocks under continued ecosystem transition.

Effects of convective available potential energy, temperature and humidity on the variability of thunderstorm frequency over Bangladesh - Md Wahiduzzaman; Md. Arfan Ali; Jing-Jia Luo; Yu Wang; Md. Jalal Uddin; Shamsuddin Shahid; A. R. M. Towfiqul Islam; Sanjit Kumar Mondal; Ubaydur Rahaman Siddiki; Muhammad Bilal; Zhongfeng Qiu; Ramzah Dambul; et al. (Theoretical and Applied Climatology, 2022)

Complete genome of the thermophilic purple sulfur Bacterium Thermochromatium tepidum compared to Allochromatium vinosum and other Chromatiaceae - W. Matthew Sattley; Wesley D. Swingley; Brad M. Burchell; Emma D. Dewey; Mackenzie K. Hayward; Tara L. Renbarger; Kathryn N. Shaffer; Lynn M. Stokes; Sonja A. Gurbani; Catrina M. Kujawa; D. Adam Nuccio; Jacob Schladweiler; et al. (Photosynthesis Research, 2022)

Chronic Stress Induced by Keeping in Conditions of Nesting Material Deficiency in the Early Postnatal Period Affects Behavior and Stress Reactivity in Male Rats - M. Yu. Stepanichev; O. A. Nedogreeva; M. A. Klimanova; Yu. V. Moiseeva; M. V. Onufriev; N. A. Lazareva; N. V. Gulyaeva (Neuroscience and Behavioral Physiology, 2022)

The Serotonin System in Mammalian Oogenesis - Yu. B. Shmukler; N. M. Alyoshina; L. A. Malchenko; D. A. Nikishin (Neuroscience and Behavioral Physiology, 2022)

Cognitive Impairments in Patients with Bipolar Affective Disorder in Remission - E. M. Chumakov; N. N. Petrova; O. V. Limankin; Yu. V. Ashenbrenner (Neuroscience and Behavioral Physiology, 2022)

Impairments to Executive Functions in Children with Dyslexia - L. S. Chutko; S. Yu. Surushkina; E. A. Yakovenko; T. I. Anisimova; M. D. Didur; S. A. Chekalova (Neuroscience and Behavioral Physiology, 2022)

Regulation of Brain Primary Cilia Length by MCH Signaling: Evidence from Pharmacological, Genetic, Optogenetic, and Chemogenic Manipulations - Wedad Alhassen; Yuki Kobayashi; Jessica Su; Brianna Robbins; Henry Nguyen; Thant Myint; Micah Yu; Surya M. Nauli; Yumiko Saito; Amal Alachkar (Molecular Neurobiology, 2022)

Tolypocladium reniformisporum sp. nov. and Tolypocladium cylindrosporum (Ophiocordycipitaceae, Hypocreales) co-occurring on Ophiocordyceps sinensis - Yao Wang; Yan-Fang Liu; De-Xiang Tang; Yuan-Bing Wang; Alison E. M. Adams; Hong Yu (Mycological Progress, 2022)

Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation - R. J. Longchamps; S. Y. Yang; C. A. Castellani; W. Shi; J. Lane; M. L. Grove; T. M. Bartz; C. Sarnowski; C. Liu; K. Burrows; A. L. Guyatt; T. R. Gaunt; et al. (Human Genetics, 2022)
Mitochondrial DNA copy number (mtDNA-CN) measured from blood specimens is a minimally invasive marker of mitochondrial function that exhibits both inter-individual and intercellular variation. To identify genes involved in regulating mitochondrial function, we performed a genome-wide association study (GWAS) in 465,809 White individuals from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium and the UK Biobank (UKB). We identified 133 SNPs with statistically significant, independent effects associated with mtDNA-CN across 100 loci. A combination of fine-mapping, variant annotation, and co-localization analyses was used to prioritize genes within each of the 133 independent sites. Putative causal genes were enriched for known mitochondrial DNA depletion syndromes ( p = 3.09 × 10 –15 ) and the gene ontology (GO) terms for mtDNA metabolism ( p = 1.43 × 10 –8 ) and mtDNA replication ( p = 1.2 × 10 –7 ). A clustering approach leveraged pleiotropy between mtDNA-CN associated SNPs and 41 mtDNA-CN associated phenotypes to identify functional domains, revealing three distinct groups, including platelet activation, megakaryocyte proliferation, and mtDNA metabolism. Finally, using mitochondrial SNPs, we establish causal relationships between mitochondrial function and a variety of blood cell-related traits, kidney function, liver function and overall ( p = 0.044) and non-cancer mortality ( p = 6.56 × 10 –4 ).

Changes in the Levels of Neurospecific Proteins and Indices of Apoptosis in the Rat Cornea at Chronic Ethanol Consumption: Protective Effects of Thiamine Administration - O. S. Pavlova; V. L. Bilous; V. V. Korsa; S. P. Stepanenko; Yu. M. Parkhomenko; A. O. Tykhomyrov (Neurophysiology, 2022)

Comparative Proteomic Analysis of the Mycoplasma gallisepticum Nucleoid Fraction before and after Infection - M. A. Galyamina; A. I. Zubov; V. G. Ladygina; A. V. Li; D. S. Matyushkina; O. V. Pobeguts; G. Yu. Fisunov (Bulletin of Experimental Biology and Medicine, 2022)

Anti-Allergic Properties of Humic Acids Isolated from Pine-Sphagnum-Cotton Sedge Peat - E. S. Trofimova; M. V. Zykova; A. A. Ligacheva; M. G. Danilets; E. Yu. Sherstoboev; L. A. Logvinova; M. V. Belousov (Bulletin of Experimental Biology and Medicine, 2022)

A Model for Recognizing Structureless Hyperpigmented Areas in Dermato-Oncology - V. G. Nikitaev; A. N. Pronichev; O. B. Tamrazova; V. Yu. Sergeev; M. A. Solomatin; O. A. Medvedeva; V. S. Kozlov (Biomedical Engineering, 2022)

Measurement of Intraocular Pressure with a Dynamic Tonometer and Presentation of Measurement Results - M. Yu. Danichenko; A. A. Mikheev (Biomedical Engineering, 2022)

Allochromatium tepidum, sp. nov., a hot spring species of purple sulfur bacteria - Michael T. Madigan; Jill N. Absher; Joseph E. Mayers; Marie Asao; Deborah O. Jung; Kelly S. Bender; Megan L. Kempher; Mackenzie K. Hayward; Sophia A. Sanguedolce; Abigail C. Brown; Shinichi Takaichi; Ken Kurokawa; et al. (Archives of Microbiology, 2022)

Is a drought a drought in grasslands? Productivity responses to different types of drought - Charles J. W. Carroll; Ingrid J. Slette; Robert J. Griffin-Nolan; Lauren E. Baur; Ava M. Hoffman; Elsie M. Denton; Jesse E. Gray; Alison K. Post; Melissa K. Johnston; Qiang Yu; Scott L. Collins; Yiqi Luo; et al. (Oecologia, 2021)

Multilayer adsorption of organic dyes on coal tar-based porous carbon with ultra-high specific surface area - X. Wang; F. Huang; M. Yu; C. Zhang; F. Ding; L. Chen; H. Chen (International Journal of Environmental Science and Technology, 2021)

The efficacy and safety of levilimab in severely ill COVID-19 patients not requiring mechanical ventilation: results of a multicenter randomized double-blind placebo-controlled phase III CORONA clinical study - Nikita V. Lomakin; Bulat A. Bakirov; Denis N. Protsenko; Vadim I. Mazurov; Gaziyavdibir H. Musaev; Olga M. Moiseeva; Elena S. Pasechnik; Vladimir V. Popov; Elena A. Smolyarchuk; Ivan G. Gordeev; Mikhail Yu Gilyarov; Darya S. Fomina; et al. (Inflammation Research, 2021)
Objective and design The aim of this double-blind, placebo-controlled, phase III CORONA clinical trial was to evaluate the efficacy and safety of IL-6 receptor inhibitor levilimab (LVL) in subjects with severe COVID-19. Subjects The study included 217 patients. The eligible were men and non-pregnant women aged 18 years or older, hospitalized for severe COVID-19 pneumonia. Treatment 206 subjects were randomized (1:1) to receive single subcutaneous administration of LVL 324 mg or placebo, both in combination with standard of care (SOC). 204 patients received allocated therapy. After the LVL/placebo administration in case of deterioration of symptoms, the investigator could perform a single open-label LVL 324 mg administration as the rescue therapy. Methods The primary efficacy endpoint was the proportion of patients with sustained clinical improvement on the 7-category ordinal scale on Day 14. All efficacy data obtained after rescue therapy administration were considered missing. For primary efficacy analysis, all subjects with missing data were considered non-responders. Results 63.1% and 42.7% of patients in the LVL and in the placebo groups, respectively, achieved sustained clinical improvement on Day 14 ( P = .0017). The frequency of adverse drug reactions was comparable between the groups. Conclusion In patients with radiologically confirmed SARS-CoV-2 pneumonia, requiring or not oxygen therapy (but not ventilation) with no signs of other active infection administration of LVL + SOC results in an increase of sustained clinical improvement rate. Trail registration The trial is registered at the US National Institutes of Health (ClinicalTrials.gov; NCT04397562).

Speciation and Potential Ecological Risk of Heavy Metals in Soils from Overlapped Areas of Farmland and Coal Resources in Northern Xuzhou, China - Y. Y. Yang; J. X. Zhang; X. Xiao; M. Du; H. J. Luan; Q. X. Yu; Y. Liang (Bulletin of Environmental Contamination and Toxicology, 2021)

Strong partitioning of soil bacterial community composition and co-occurrence networks along a small-scale elevational gradient on Zijin Mountain - Xu Liu; Teng Yang; Yu Shi; Yichen Zhu; Mulin He; Yunke Zhao; Jonathan M. Adams; Haiyan Chu (Soil Ecology Letters, 2021)

Expression and Content of Protein LC3B in Gastric Cancer Tissue, Relationship with Expression of mTOR, AMPK in Gastric Cancer Tissue and HER2 and PD-L1 Status of the Tumor - L. V. Spirina; A. V. Avgustinovich; S. G. Afanas’ev; M. Yu. Volkov; I. V. Kondakova (Bulletin of Experimental Biology and Medicine, 2021)

Cure of Mice with Advanced Ovarian Adenocarcinoma CaO1 by the Serum Blood Proteins - F. V. Donenko; S. M. Sitdikova; Yu. I. Dolzhikova; Yu. S. Lebedin (Bulletin of Experimental Biology and Medicine, 2021)

Improved Survival and Regeneration of Irradiated Mouse Neural Stem Cells after Co-Culturing with Non-Irradiated Mouse Neural Stem Cells or Mesenchymal Stem Cells from the Adipose Tissue - M. G. Ratushnyak; Yu. P. Semochkina; A. S. Zhirnik; O. D. Smirnova (Bulletin of Experimental Biology and Medicine, 2021)

The Influence of Water-Soluble Polysaccharides of Crataegus sanguinea Pall. on Nitric Oxide Production by Macrophages - A. A. Ligacheva; E. Yu. Sherstoboev; M. G. Danilets; E. S. Trofimova; S. V. Krivoshchekov; S. R. Khasanova; N. V. Kudashkina; A. M. Gur’ev; M. V. Belousov (Bulletin of Experimental Biology and Medicine, 2021)

Monooxygenase System and NO Metabolism in Liver Microsomes of Rats with Toxic Hepatitis and the Effect of Sesquiterpene Lactones - N. V. Tursunova; V. N. Syrov; Z. A. Khushbaktova; Yu. V. Tornuev; M. G. Klinnikova (Bulletin of Experimental Biology and Medicine, 2021)

Household environmental microbiota influences early‐life eczema development - Le Duc Huy Ta; Carina Jing Xuan Tay; Christophe Lay; Paola Florez de Sessions; Cheryl Pei Ting Tan; Michelle Jia Yu Tay; Hui Xing Lau; Atiqa Binte Zulkifli; Gaik Chin Yap; Elizabeth Huiwen Tham; Eliza Xin Pei Ho; Anne Eng Neo Goh; et al. (Environmental Microbiology, 2021)
Summary Exposure to a diverse microbial environment during pregnancy and early postnatal period is important in determining predisposition towards allergy. However, the effect of environmental microbiota exposure during preconception, pregnancy and postnatal life on development of allergy in the child has not been investigated so far. In the S‐PRESTO (Singapore PREconception Study of long Term maternal and child Outcomes) cohort, we collected house dust during all three critical window periods and analysed microbial composition using 16S rRNA gene sequencing. At 6 and 18 months, the child was assessed for eczema by clinicians. In the eczema group, household environmental microbiota was characterized by presence of human‐associated bacteria Actinomyces , Anaerococcus, Finegoldia, Micrococcus, Prevotella and Propionibacterium at all time points, suggesting their possible contributions to regulating host immunity and increasing the susceptibility to eczema. In the home environment of the control group, putative protective effect of an environmental microbe Planomicrobium ( Planococcaceae family) was observed to be significantly higher than that in the eczema group. Network correlation analysis demonstrated inverse relationships between beneficial Planomicrobium and human‐associated bacteria ( Actinomyces , Anaerococcus, Finegoldia, Micrococcus, Prevotella and Propionibacterium ). Exposure to natural environmental microbiota may be beneficial to modulate shed human‐associated microbiota in an indoor environment.

Optimizing the Design of Blood–Brain Barrier-Penetrating Polymer-Lipid-Hybrid Nanoparticles for Delivering Anticancer Drugs to Glioblastoma - Taksim Ahmed; Fuh-Ching Franky Liu; Chungsheng He; Azhar Z. Abbasi; Ping Cai; Andrew M. Rauth; Jeffery T. Henderson; Xiao Yu Wu (Pharmaceutical Research, 2021)

Bodipy Based Fluorescent Materials in Cellulose Matrices: Synthesis, Spectral Properties and Vapochromic Fluorescent Recognition of Alcohols and Acetone - A. V. Bobrov; M. V. Kishalova; A. A. Ksenofontov; S. D. Usoltsev; Yu. S. Marfin (Journal of Fluorescence, 2021)

Simultaneous adoption of diversification and agricultural credit to manage catastrophic risk for maize production in Bangladesh - K M Mehedi Adnan; Liu Ying; Swati Anindita Sarker; Man Yu; Riffat Ara Zannat Tama (Environmental Science and Pollution Research, 2021)

Leading cancers contributing to educational disparities in cancer mortality in the US, 2017 - Diana R. Withrow; Neal D. Freedman; James T. Gibson; Mandi Yu; Anna M. Nápoles; Amy Berrington de González; Meredith S. Shiels (Cancer Causes & Control, 2021)
Purpose To inform prevention efforts, we sought to determine which cancer types contribute the most to cancer mortality disparities by individual-level education using national death certificate data for 2017. Methods Information on all US deaths occurring in 2017 among 25–84-year-olds was ascertained from national death certificate data, which include cause of death and educational attainment. Education was classified as high school or less (≤ 12 years), some college or diploma (13–15 years), and Bachelor's degree or higher (≥ 16 years). Cancer mortality rate differences (RD) were calculated by subtracting age-adjusted mortality rates (AMR) among those with ≥ 16 years of education from AMR among those with ≤ 12 years. Results The cancer mortality rate difference between those with a Bachelor's degree or more vs. high school or less education was 72 deaths per 100,000 person-years. Lung cancer deaths account for over half (53%) of the RD for cancer mortality by education in the US. Conclusion Efforts to reduce smoking, particularly among persons with less education, would contribute substantially to reducing educational disparities in lung cancer and overall cancer mortality.

Microbial communities associated with the ostracods Candona sp. inhabiting the area of the methane seep Goloustnoye (Lake Baikal) - I. A. Khalzov; S. V. Bukin; A. S. Zakharenko; S. M. Chernitsyna; Yu. P. Galachyants; T. Ya. Sitnikova; T. I. Zemskaya (Symbiosis, 2021)

Optically active centers in brown type IaAB diamonds from the Istok placer in the northeastern Siberian Platform: spectroscopic properties and the effect of HPHT treatment - V. A. Nadolinny; Yu N. Palyanov; V. S. Shatsky; A. A. Kalinin; A. Yu Komarovskikh; M. I. Rakhmanova; O. P. Yuryeva; M. N. Uvarov; S. S. Yakushkin; M. I. Guskova (Physics and Chemistry of Minerals, 2021)

Colony-Forming Ability and Residual Foci of DNA Repair Proteins in Human Lung Fibroblasts Irradiated with Subpicosecond Beams of Accelerated Electrons - N. S. Babayan; D. V. Guryev; N. Yu. Vorobyeva; B. A. Grigoryan; G. L. Tadevosyan; L. S. Apresyan; A. K. Chigasova; E. I. Yashkina; S. M. Rodneva; A. A. Tsishnatti; Yu. A. Fedotov; N. K. Sarkisyan; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Morphofunctional Properties of Corneal Stromal Cells - M. A. Surovtseva; O. V. Poveshchenko; K. Yu. Krasner; I. I. Kim; A. P. Lykov; N. A. Bondarenko; L. A. Shul’mina; A. N. Trunov; V. V. Chernykh (Bulletin of Experimental Biology and Medicine, 2021)

Development of a Purified Viral Preparation for Studies of COVID-19 (SARS-CoV-2) Biology - A. A. Chepurnov; E. I. Kazachinskaya; E. A. Kazachkova; K. A. Sharshov; Yu. V. Kononova; A. A. Shelemba; A. Yu. Alekseev; M. A. Gulyeva; M. I. Voevoda; A. M. Shestopalov (Bulletin of Experimental Biology and Medicine, 2021)

Detection of Circles as Structural Elements in Dermatoscopic Images of Skin Neoplasms in the Diagnosis of Melanoma - V. G. Nikitaev; A. N. Pronichev; O. B. Tamrazova; V. Yu. Sergeev; O. A. Medvedeva; V. S. Kozlov; M. A. Solomatin (Biomedical Engineering, 2021)

A Device for Comprehensive Noninvasive Diagnostics of the Tissue Microcirculation System of Human Skin - V. V. Sidorov; Yu. L. Rybakov; V. M. Gukasov; G. S. Evtushenko (Biomedical Engineering, 2021)

Application of advanced molecular spectroscopy and modern evaluation techniques in canola molecular structure and nutrition property research - Walaa M. S. Gomaa; Xin Feng; Huihua Zhang; Xuewei Zhang; Weixian Zhang; Xiaogang Yan; Quanhui Peng; Peiqiang Yu (Critical Reviews in Food Science and Nutrition, 2021)

Walleye Pollock Gadus chalcogrammus, a Species with Continuous Range from the Norwegian Sea to Korea, Japan, and California: New Records from the Siberian Arctic - Alexei M. Orlov; Maxim O. Rybakov; Elena V. Vedishcheva; Alexander A. Volkov; Svetlana Yu. Orlova (Journal of Marine Science and Engineering, 2021)
The first records of walleye pollock Gadus chalcogrammus Pallas, 1814 in the seas of the Siberian Arctic (the Laptev Sea, the Kara Sea, the southeastern Barents Sea), are documented. Information about the external morphology (morphometric and meristic characters), photos of sagittal otoliths and fish, and data on the sequences of the CO1 mtDNA gene are presented. The results of a comparative analysis indicate that walleye pollock caught in the Siberian Arctic do not differ in principle from North Pacific and North Atlantic individuals. Previous conclusions about the conspecificity of the walleye and Norwegian pollock Theragra finnmarchica are confirmed. New captures of walleye pollock in the Siberian Arctic allow us to formulate a hypothesis about its continuous species’ range from the coasts of Norway in the North Atlantic to the coasts of Korea, Japan, and California in the North Pacific. The few records of walleye pollock in the North Atlantic originate from the North Pacific due to the transport of early pelagic juveniles to the Arctic by currents through the Bering Strait and further active westward migrations of individuals which have switched to the bentho-pelagic mode of life.

Expression of glutamate dehydrogenase genes in Arabidopsis thaliana depends on the redox state of plastoquinone pool - Elena Yu. Garnik; Vadim I. Belkov; Vladislav I. Tarasenko; Alexandr V. Rudikovskii; Yuri M. Konstantinov (Plant Cell, Tissue and Organ Culture (PCTOC), 2021)

High-Definition Transcranial Direct Current Electrical Stimulation - A. G. Poydasheva; I. S. Bakulin; D. Yu. Lagoda; E. L. Pavlova; N. A. Suponeva; M. A. Piradov (Neuroscience and Behavioral Physiology, 2021)

Development of Early Diagnosis of Parkinson’s Disease Using Premotor Symptoms and Blood Changes as Biomarkers - E. I. Gusev; E. A. Katunina; M. Yu. Martinov; V. E. Blokhin; A. L. Kalinkin; A. V. Alesenko; M. R. Nodel; E. A. Malykhina; N. V. Titova; D. A. Katunin; M. A. Shupik; U. A. Gutner; et al. (Neuroscience and Behavioral Physiology, 2021)

Point of Care Blood Gas and Electrolyte Analysis in Anesthetized Olive Baboons (Papio anubis) in a Field Setting - Maureen W. Kamau; James M. Hassell; Ellie L. Milnes; Lee-Ann C. Hayek; Mathew M. Mutinda; Roi Harel; Akiko Matsumoto-Oda; Jennifer H. Yu; Dawn Zimmerman; Margaret Crofoot; Suzan Murray (International Journal of Primatology, 2021)

Novel compound heterozygous missense mutations in GDAP1 cause Charcot–Marie–Tooth type 4A - HUIQIN XUE; NEVEN MAKSEMOUS; DAVID SIDHOM; LAN MA; SHAOHUI CHEN; JIANRUI WU; YU FENG; LARISA M. HAUPT; LYN R. GRIFFITHS (Journal of Genetics, 2021)

A Method of Direct Quantitation of Lactobacillus spp. in Intestinal Contents Based on Real-Time PCR - Yu. M. Markova; V. V. Stetsenko; A. S. Polyanina (Bulletin of Experimental Biology and Medicine, 2021)

Association between Molecular Genetic Markers of DNA Repair and Cell Cycle Control Genes and Response to Platinum-Based Chemotherapy in Ovarian Cancer Patients - T. M. Zavarikina; S. V. Khokhlova; A. S. Tyulyandina; G. N. Khabas; A. V. Asaturova; Yu. V. Nosova; P. K. Brenner; M. A. Kapralova; D. S. Khodirev; M. B. Stenina (Bulletin of Experimental Biology and Medicine, 2021)

Isolation of Nucleoid Fraction from Mycoplasma gallisepticum Cells with Synchronized Cell Division - A. I. Zubov; V. G. Ladygina; M. A. Galyamina; O. V. Pobeguts; G. Yu. Fisunov (Bulletin of Experimental Biology and Medicine, 2021)

Age-Related Features of the Viscosity of Plasma and Mitochondrial Membranes of Hepatocytes in Liver Cirrhosis - E. G. Skurikhin; S. A. Afanas’ev; M. A. Zhukova; T. Yu. Rebrova; E. F. Muslimova; E. S. Pan; N. N. Ermakova; O. V. Pershina; A. V. Pakhomova; O. D. Putrova; L. A. Sandrikina; L. V. Kogai; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Allelopathic and competitive interactions between native and alien plants - Ling Yuan; Jun-Min Li; Fei-Hai Yu; Ayub M. O. Oduor; Mark van Kleunen (Biological Invasions, 2021)
The novel-weapons and homeland-security hypotheses are based on the idea that aliens and natives are not adapted to each other’s allelochemicals as they did not co-evolve. However, as only a few studies have tested this, it remains unclear how important co-evolutionary history is in determining the strength of allelopathic interactions between aliens and natives. Here, we tested for potential pairwise allelopathic effects on each other of five alien and five native herbaceous species in China. We did a germination experiment and a competition experiment. In the germination experiment, we tested whether aqueous extracts of the ten study species had allelopathic effects on each other’s seed germination. In the competition experiment, we tested whether the alien and native species differed in their competitive effects and responses, and whether these were changed by the presence of activated carbon—a presumed allelopathy neutralizer– in the soil. Plant extracts had negative allelopathic effects on seed germination. This was particularly the case for extracts from the native species. Moreover, aqueous extracts had slightly stronger negative effects on germination of the aliens than on germination of the natives. In the competition experiment, on the other hand, the natives suffered more from competition than the alien species did, but we could not relate this to allelopathy. Alien plants had negative competitive and allelopathic effects on native plants, but the reverse was also true. These alien-native interactions, however, were not consistently stronger or weaker than native-native or alien-alien interactions.

Correction to: Inter‑ and intraspecific variability of morphometric parameters of rodent spermatozoa - G. Yu. Smirnov; M. V. Modorov; Yu. A. Davydova (Zoomorphology, 2021)

Inter- and intraspecific variability of morphometric parameters of rodent spermatozoa - G. Yu. Smirnov; M. V. Modorov; Yu. A. Davydova (Zoomorphology, 2021)

Down-Regulation of the Ultraviolet-Sensitive Visual Pigment of the Cockroach Decreases the Masking Effect in Short-Wavelength Illumination - E. S. Novikova; I. Yu. Severina; I. L. Isavnina; M. I. Zhukovskaya (Neuroscience and Behavioral Physiology, 2021)

Analysis of Paradoxical Neurophysiological Reactions at Different Stages of the Perception of Negative Emotional Stimuli in Schizophrenia Patients - V. B. Strelets; G. I. Rodionov; M. K. Nurbekov; V. L. Ushakov; A. Yu. Arkhipov (Neuroscience and Behavioral Physiology, 2021)

Effects of Daytime Sleep Inertia on the Recognition of Barely Distinguishable Sounds - M. O. Shilov; K. M. Liaukovich; O. V. Martynova; Yu. V. Ukraintseva (Neuroscience and Behavioral Physiology, 2021)

Clinical-Morphological Risk Factors for the Development of Epilepsy in Patients with Glial and Metastatic Brain Tumors - M. Yu. Prokudin; M. M. Odinak; I. V. Litvinenko; B. V. Martynov; D. V. Svistov; S. E. Bushurov; O. A. Klitsenko (Neuroscience and Behavioral Physiology, 2021)

Direct and Indirect Neurological Signs of COVID-19 - O. A. Gromova; I. Yu. Torshin; V. A. Semenov; M. V. Putilina; A. G. Chuchalin (Neuroscience and Behavioral Physiology, 2021)

Hydrodynamic model of blood flow in major arteries pulsing in various modes - Yu. M. Belousov; V. P. Krainov; S. V. Revenko (Medical & Biological Engineering & Computing, 2021)

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus - Pik Fang Kho; Sally Mortlock; Frederic Amant; Daniela Annibali; Katie Ashton; John Attia; Paul L. Auer; Matthias W. Beckmann; Amanda Black; Louise Brinton; Daniel D. Buchanan; Stephen J. Chanock; et al. (Human Genetics, 2021)

Secretory Phospholipase A2 Enzymes in Acute Lung Injury - Eleftheria Letsiou; Yu Maw Htwe; Steven M. Dudek (Cell Biochemistry and Biophysics, 2021)

Specific Cytotoxicity of Targeted 177Lu and 212Pb-Based Radiopharmaceuticals - A. A. Pankratov; E. R. Nemtsova; A. D. Plyutinskaya; M. S. Vorontsova; D. Yu. Chuvilin; B. V. Egorova; K. V. Kokov; S. M. Deev; E. N. Lebedenko; G. M. Proshkina; A. A. Shul’ga; V. A. Golovachenko; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Complex Interaction of Platelets, von Willebrand Factor and Leukocytes, in Whole Blood at High Shear Rates Is Mediated by Platelet GPIIb/IIIa Receptor - Yu. N. Avtaeva; I. S. Mel’nikov; O. S. Saburova; K. G. Guriya; M. C. Osidak; C. P. Domogatsky; Z. A. Gabbasov (Bulletin of Experimental Biology and Medicine, 2021)

Putative Role of Ligands of DNIC in the Physiological Action of the Complex - V. Yu. Titov; A. M. Dolgorukova; A. N. Osipov; I. I. Kochish (Bulletin of Experimental Biology and Medicine, 2021)

Expression of Bax and Bcl-2 Proteins in Left-Ventricular Cardiomyocytes in Wistar-Kyoto and SHR Rats with Insulin-Dependent Diabetes Mellitus - A. P. Sklifasovskaya; M. L. Blagonravov; A. Yu. Ryabinina; M. M. Azova; V. A. Goryachev (Bulletin of Experimental Biology and Medicine, 2021)

Model of a Decision-Making System for the Diagnosis of Melanoma Using Artificial Intelligence - V. G. Nikitaev; A. N. Pronichev; O. B. Tamrazova; V. Yu. Sergeev; E. A. Druzhinina; O. A. Medvedeva; M. A. Solomatin (Biomedical Engineering, 2021)

Assessment of the Time Characteristics of Walking Techniques Using a Mobile Information and Measurement System - V. V. Alekseev; N. E. Ivanova; A. Yu. Ivanov; P. G. Korolev; F. M. Sokolova; A. V. Tsareva (Biomedical Engineering, 2021)

Activation of Repair Processes in Patients with Bedsores Using Pulsed Radio-Frequency Currents - S. V. Belov; Yu. K. Danyleiko; A. B. Egorov; V. I. Lukanin; V. B. Tsvetkov; E. G. Osmanov; A. M. Shulutko; E. L. Altukhov; A. A. Yakovlev (Biomedical Engineering, 2021)

Intracavity Thermometry in Medicine - M. K. Sedankin; A. G. Gudkov; S. G. Vesnin; A. A. Konovalova; V. Yu. Leushin; Yu. V. Solov’ev; I. A. Sidorov; S. V. Agasieva; S. V. Chizhikov; E. N. Gorlacheva (Biomedical Engineering, 2021)

The bacterium Pseudomonas protegens antagonizes the microalga Chlamydomonas reinhardtii using a blend of toxins - Magdalena M. Rose; Daniel Scheer; Yu Hou; Vivien S. Hotter; Anna J. Komor; Prasad Aiyar; Kirstin Scherlach; Fredd Vergara; Qing Yan; Joyce E. Loper; Torsten Jakob; Nicole M. van Dam; et al. (Environmental Microbiology, 2021)
Summary The unicellular alga Chlamydomonas reinhardtii and the bacterium Pseudomonas protegens serve as a model to study the interactions between photosynthetic and heterotrophic microorganisms. P . protegens secretes the cyclic lipopeptide orfamide A that interferes with cytosolic Ca 2+ homeostasis in C . reinhardtii resulting in deflagellation of the algal cells. Here, we studied the roles of additional secondary metabolites secreted by P . protegens using individual compounds and co‐cultivation of algae with bacterial mutants. Rhizoxin S2, pyrrolnitrin, pyoluteorin, 2,4‐diacetylphloroglucinol (DAPG) and orfamide A all induce changes in cell morphology and inhibit the growth of C . reinhardtii . Rhizoxin S2 exerts the strongest growth inhibition, and its action depends on the spatial structure of the environment (agar versus liquid culture). Algal motility is unaffected by rhizoxin S2 and is most potently inhibited by orfamide A (IC 50 = 4.1 μM). Pyrrolnitrin and pyoluteorin both interfere with algal cytosolic Ca 2+ homeostasis and motility whereas high concentrations of DAPG immobilize C . reinhardtii without deflagellation or disturbance of Ca 2+ homeostasis. Co‐cultivation with a regulatory mutant of bacterial secondary metabolism (Δ gacA ) promotes algal growth under spatially structured conditions. Our results reveal how a single soil bacterium uses an arsenal of secreted antialgal compounds with complementary and partially overlapping activities.

Legal Issues for Artificial Floating Islands - Maarten M. B. Flikkema; Fen-Yu (Vicky) Lin; Pernille P. J. van der Plank; Jos Koning; Olaf Waals (Frontiers in Marine Science, 2021)
Developments of multi-use floating islands are accelerated by an increase in offshore activities and pressing needs to create extra space in coastal regions for the surging population. The Horizon 2020 EU funded research project Space@Sea developed a modular floating island concept for offshore multi-use applications and examined current legal issues and barriers concerning its development. In this paper a floating island is defined to be “an artificially created floater, or set of connected floaters, moored to the seabed of which the topside can be used for activities similar to activities on land”. This paper aims to delve into governance issues like the assignment of authority on a multi-use floating island and the shift from regulating offshore living for working purposes to living purposes, as well as maritime law and property law (using the Netherlands as case study). Within the Exclusive Economic Zone (EEZ) a coastal state can establish, locate, and govern the floating island. For the high seas the International Maritime Organization (IMO) is the most probable organization to initiate a discussion on settlement of floating islands. For each activity on the floating island, limiting criteria regarding motions as well as safety rules and regulations need to be established. Industry and housing will have completely different requirements regarding safety which will not be possible to fit in a one size fits all regulation. This case study shows that current Dutch property law prohibit the division of ownership of buildings built on floating objects. They can only be owned together as one object. For urban expansion, future inhabitants will want to have the possibility to buy property, requiring an amendment of current property law. It is to be expected that other countries will have similar or additional governance challenges. The Space@Sea project has developed a technical solution for floating islands which have identified barriers for multi-use in the rules and regulations described in this paper. The paper urges the responsible institutions and stakeholders to take on their roles in overcoming these barriers.

Influence of Heavy Metals and Arsenic on Survival and Biofilm Formation of Some Saprotrophic Soil Microorganisms - V. A. Bybin; G. A. Belogolova; Yu. A. Markova; M. G. Sokolova; A. V. Sidorov; O. N. Gordeeva; V. I. Poletaeva (Water, Air, & Soil Pollution, 2021)

In situ cosmogenic 10Be, 26Al, and 21Ne dating in sediments from the Guizhou Plateau, southwest China - Ye Yang; Yu Liu; Yan Ma; Sheng Xu; Cong-Qiang Liu; Shi-Jie Wang; Finlay M. Stuart; Derek Fabel (Science China Earth Sciences, 2021)

Mechanisms of Candida Resistance to Antimycotics and Promising Ways to Overcome It: The Role of Probiotics - Konstantin A. Demin; Aleksandr G. Refeld; Anna A. Bogdanova; Evgenya V. Prazdnova; Igor V. Popov; Olga Yu. Kutsevalova; Alexey M. Ermakov; Anzhelica B. Bren; Dmitry V. Rudoy; Vladimir A. Chistyakov; Richard Weeks; Michael L. Chikindas (Probiotics and Antimicrobial Proteins, 2021)

The last refugia for a polar relict pollinator: isolates of Bombus glacialis on Novaya Zemlya and Wrangel Island indicate its broader former range in the Pleistocene - Grigory S. Potapov; Mikhail V. Berezin; Yulia S. Kolosova; Alexander V. Kondakov; Alena A. Tomilova; Vitaly M. Spitsyn; Alisa A. Zheludkova; Natalia A. Zubrii; Boris Yu. Filippov; Ivan N. Bolotov (Polar Biology, 2021)

LA-ICPMS U-Pb dating reveals cassiterite inheritance in the Yazov granite, Eastern Siberia: Implications for tin mineralization - L. A. Neymark; C. S. Holm-Denoma; A. M. Larin; R. J. Moscati; Yu. V. Plotkina (Mineralium Deposita, 2021)

Deletion of Nrip1 delays skin aging by reducing adipose-derived mesenchymal stem cells (ADMSCs) senescence, and maintaining ADMSCs quiescence - Yu Hu; Yun Zhu; Skyler D. Gerber; Jared M. Osland; Min Chen; Krishna A. Rao; Heng Gu; Rong Yuan (GeroScience, 2021)

The Role of Intracellular Signaling Molecules in the Production of Granulocytic CSF Mononuclear Phagocytes in Stress and Cytostatic Influence - V. V. Zhdanov; L. A. Miroshnichenko; G. N. Zyuz’kov; T. Yu. Khrichkova; E. V. Udut; E. V. Simanina; E. Yu. Sherstoboev; L. A. Stavrova; V. I. Agafonov; M. G. Danilets; E. S. Trofimova; M. Yu. Minakova; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Features of the Population of Mouse Peritoneal Macrophages Isolated after Stimulation with Concanavalin A and Thioglycolate - E. S. Zubkova; K. V. Dergilev; I. B. Beloglazova; Yu. D. Molokotina; M. A. Boldyreva; Z. I. Tsokolaeva; I. S. Stafeev; M. Yu. Menshikov; Ye. V. Parfyonova (Bulletin of Experimental Biology and Medicine, 2021)

Osteogenic Commitment of MSC Is Enhanced after Interaction with Umbilical Cord Blood Mononuclear Cells In Vitro - E. R. Andreeva; M. I. Ezdakova; P. I. Bobyleva; I. V. Andrianova; A. Yu. Ratushnyy; L. B. Buravkova (Bulletin of Experimental Biology and Medicine, 2021)

Mechanisms of Endothelial-to-Mesenchymal Transition Induction by Extracellular Matrix Components in Pulmonary Fibrosis - O. A. Grigorieva; M. A. Vigovskiy; U. D. Dyachkova; N. A. Basalova; N. A. Aleksandrushkina; M. A. Kulebyakina; I. L. Zaitsev; V. S. Popov; A. Yu. Efimenko (Bulletin of Experimental Biology and Medicine, 2021)

Comparative In Vitro Study of Antiherpetic Activity of Echinochrome A and Product of Its Oxidation Dehydroechinochrome - O. V. Iunikhina; N. V. Krylova; N. P. Mishchenko; E. A. Vasileva; S. A. Fedoreyev; M. Yu. Shchelkanov (Bulletin of Experimental Biology and Medicine, 2021)

Size compartmentalization of energy channeling in terrestrial belowground food webs - Anton M. Potapov; Oksana L. Rozanova; Eugenia E. Semenina; Vladislav D. Leonov; Olga I. Belyakova; Varvara Yu. Bogatyreva; Maxim I. Degtyarev; Anton S. Esaulov; Anastasiya Yu. Korotkevich; Alexey A. Kudrin; Elena A. Malysheva; Yuri A. Mazei; et al. (Ecology, 2021)
Size‐structured food webs form integrated trophic systems where energy is channeled from small to large consumers. Empirical evidence suggests that size structure prevails in aquatic ecosystems, whereas in terrestrial food webs trophic position is largely independent of body size. Compartmentalization of energy channeling according to size classes of consumers was suggested as a mechanism that underpins functioning and stability of terrestrial food webs including those belowground, but their structure has not been empirically assessed across the whole size spectrum. Here we used stable isotope analysis and metabolic regressions to describe size structure and energy use in eight belowground communities with consumers spanning 12 orders of magnitude in living body mass, from protists to earthworms. We showed a negative correlation between trophic position and body mass in invertebrate communities and a remarkable nonlinearity in community metabolism and trophic positions across all size classes. Specifically, we found that the correlation between body mass and trophic level is positive in the small‐sized (protists, nematodes, arthropods below 1 μg in body mass), neutral in the medium‐sized (arthropods of 1 μg to 1 mg), and negative in the large‐sized consumers (large arthropods, earthworms), suggesting that these groups form compartments with different trophic organization. Based on this pattern, we propose a concept of belowground food webs being composed of (1) size‐structured micro‐food web driving fast energy channeling and nutrient release, for example in microbial loop; (2) arthropod macro‐food web with no clear correlation between body size and trophic level, hosting soil arthropod diversity and subsidizing aboveground predators; and (3) “trophic whales,” sequestering energy in their large bodies and restricting its propagation to higher trophic levels in belowground food webs. The three size compartments are based on a similar set of basal resources, but contribute to different ecosystem‐level functions and respond differently to variations in climate, soil characteristics and land use. We suggest that the widely used vision of resource‐based energy channeling in belowground food webs can be complemented with size‐based energy channeling, where ecosystem multifunctionality, biodiversity, and stability are supported by a balance across individual size compartments.

Methane-Derived Authigenic Carbonates on the Seafloor of the Laptev Sea Shelf - Marina D. Kravchishina; Alla Yu Lein; Mikhail V. Flint; Boris V. Baranov; Alexey Yu Miroshnikov; Elena O. Dubinina; Olga M. Dara; Andrey G. Boev; Alexander S. Savvichev (Frontiers in Marine Science, 2021)
Seafloor authigenic carbonate crusts are widespread in various oceanic and marine settings, excluding high-latitude basins that are corrosive to carbonate precipitation. Newly formed carbonate formations are relatively rare in modern Arctic marine sediments. Although the first-order principles of seep carbonate formation are currently quite well constrained, little is known regarding the duration or mode of carbonate formation in the Siberian Arctic shelf. Large (massive slabs or blocks) and small crusts that were micrite cemented have been recently discovered on the seafloor of the Siberian Arctic seas within the area of known seep activity in the outer Laptev Sea shelf. Cold methane seeps were detected in the area due to the presence of an acoustic anomaly in the water column (gas flares). Microbial mats, methane gas bubbles, and carbonate crusts were observed using a towed camera platform. Here, we report new geochemical and mineralogical data on authigenic shallow Siberian Arctic cold-seep carbonate crusts to elucidate its genesis. The Laptev Sea carbonate crusts mainly consist of high-Mg calcite (up to 23 mol % MgCO 3 ). The δ 13 C values in carbonates range significantly (from –40.1 to –25.9‰ VPDB), while the δ 18 O values vary in a narrow range (+4.4 ± 0.2‰ VPDB). The δ 13 C values of C org that was determined from carbonates range from –40.2 to –31.1‰ VPDB. Using the isotope data and taking into account the geological setting, we consider that not only microbial but possibly thermogenic methane participated in the authigenic carbonate precipitation. Carbonate crust formation occurred below the water/sediment interface of the shallow Siberian Arctic shelf as a result of gas hydrate dissociation during Holocene warming events. The studied carbonate crusts were exhumated after precipitation into shallow subsurface shelf sediments.

Chemicals from lignocellulosic biomass: A critical comparison between biochemical, microwave and thermochemical conversion methods - Iris K. M. Yu; Huihui Chen; Felix Abeln; Hadiza Auta; Jiajun Fan; Vitaly L. Budarin; James H. Clark; Sophie Parsons; Christopher J. Chuck; Shicheng Zhang; Gang Luo; Daniel C.W Tsang (Critical Reviews in Environmental Science and Technology, 2021)

Developmental Dynamics of the Functional State of the Retina in Mice with Inherited Photoreceptor Degeneration - A. A. Goriachenkov; A. Yu. Rotov; M. L. Firsov (Neuroscience and Behavioral Physiology, 2021)

Experimental Models of Cognitive Impairments in Schizophrenia - M. V. Dorofeikova; E. O. Kutcher; N. N. Petrova; A. Yu. Egorov (Neuroscience and Behavioral Physiology, 2021)

Impaired Memory Formation and the Development of Transient Cholinergic Deficit in Mice after Olfactory Bulbectomy - O. A. Nedogreeva; N. A. Lazareva; M. Yu. Stepanichev; N. V. Gulyaeva (Neuroscience and Behavioral Physiology, 2021)

Brain Tractography in Diabetes Mellitus and Cognitive Impairments - Yu. G. Samoilova; M. V. Matveeva; O. S. Tonkikh; D. A. Kudlay; O. A. Oleinik; N. Yu. Fimushkina; O. M. Gerget; A. A. Borisova (Neuroscience and Behavioral Physiology, 2021)

Age-Related Characteristics of Sleep Impairments in a Model of the Preclinical Stage of Parkinson’s Disease in Rats - I. V. Ekimova; M. A. Guzeev; V. V. Simonova; Yu. F. Pastukhov (Neuroscience and Behavioral Physiology, 2021)

Time as a Measure of Consciousness. Subjective Time in Waking and Different Sleep Phases - Yu. V. Ukraintseva; K. M. Liaukovich; M. O. Shilov (Neuroscience and Behavioral Physiology, 2021)

Sequence data from isolated lichen-associated melanized fungi enhance delimitation of two new lineages within Chaetothyriomycetidae - Lucia Muggia; Yu Quan; Cécile Gueidan; Abdullah M. S. Al-Hatmi; Martin Grube; Sybren de Hoog (Mycological Progress, 2021)
Lichen thalli provide a long-lived and stable habitat for colonization by a wide range of microorganisms. Increased interest in these lichen-associated microbial communities has revealed an impressive diversity of fungi, including several novel lineages which still await formal taxonomic recognition. Among these, members of the Eurotiomycetes and Dothideomycetes usually occur asymptomatically in the lichen thalli, even if they share ancestry with fungi that may be parasitic on their host. Mycelia of the isolates are characterized by melanized cell walls and the fungi display exclusively asexual propagation. Their taxonomic placement requires, therefore, the use of DNA sequence data. Here, we consider recently published sequence data from lichen-associated fungi and characterize and formally describe two new, individually monophyletic lineages at family, genus, and species levels. The Pleostigmataceae fam. nov. and Melanina gen. nov. both comprise rock-inhabiting fungi that associate with epilithic, crust-forming lichens in subalpine habitats. The phylogenetic placement and the monophyly of Pleostigmataceae lack statistical support, but the family was resolved as sister to the order Verrucariales. This family comprises the species Pleostigma alpinum sp. nov., P. frigidum sp. nov., P. jungermannicola, and P. lichenophilum sp. nov. The placement of the genus Melanina is supported as a lineage within the Chaetothyriales. To date, this genus comprises the single species M. gunde-cimermaniae sp. nov. and forms a sister group to a large lineage including Herpotrichiellaceae, Chaetothyriaceae, Cyphellophoraceae, and Trichomeriaceae. The new phylogenetic analysis of the subclass Chaetothyiomycetidae provides new insight into genus and family level delimitation and classification of this ecologically diverse group of fungi.

Roundup negatively impacts the behavior and nerve function of the Madagascar hissing cockroach (Gromphadorhina portentosa) - Megha Kanabar; Samuel Bauer; Zimuzo M. Ezedum; Ian P. Dwyer; William S. Moore; Gabriella Rodriguez; Aditya Mall; Anne T. Littleton; Michael Yudell; Jenil Kanabar; Wade J. Tucker; Emily R. Daniels; et al. (Environmental Science and Pollution Research, 2021)

Role of JNK and p53 in Implementation of Functions of Various Types of Regeneration-Competent Cells of the Nervous Tissue - G. N. Zyuz’kov; V. V. Zhdanov; L. A. Miroshnichenko; T. Yu. Polyakova; E. V. Simanina; L. A. Stavrova; M. G. Danilets; V. I. Agafonov; A. V. Chaikovskii (Bulletin of Experimental Biology and Medicine, 2021)

Noninvasive Measurement of the Glucose Level in Biological Media Based on Diffuse Reflectance Spectroscopy - K. V. Pozhar; M. O. Mikhailov; E. A. Polyakova; E. L. Litinskaia; Yu. E. Abolemova (Biomedical Engineering, 2021)

A Model for Recognition of Dermatoscopic Points in Images of Skin Neoplasms - V. G. Nikitaev; A. N. Pronichev; O. B. Tamrazova; V. Yu. Sergeev; M. A. Solomatin; L. S. Kruglova; V. S. Kozlov; E. A. Druzhinina (Biomedical Engineering, 2021)

Studies of the Effective Thermal Conductivity of Sandstone Under High Pressure and Temperature - S. N. Emirov; A. A. Aliverdiev; Yu. P. Zarichnyak; R. M. Emirov (Rock Mechanics and Rock Engineering, 2021)

Effects of Prenatal and Early Postnatal Administration of Valproate on Behavior and Cyhtological Characteristics in Wistar Rats - V. R. Gedzun; M. M. Svinov; N. Yu. Sarycheva; P. S. Shlapakova; K. O. Dovbnyuk; V. A. Dubynin (Neuroscience and Behavioral Physiology, 2021)

Robotic Restoration of Gait Function in Patients in the Early Recovery Period of Stroke - S. V. Kotov; E. V. Isakova; V. Yu. Lijdvoy; K. A. Petrushanskaya; E. V. Pismennaya; M. V. Romanova; L. Kh. Kodzokova (Neuroscience and Behavioral Physiology, 2021)

Assessment of Neuron-Specific Enolase and Brain-Derived Neurotrophic Factor Levels at Rehabilitation Stages in the Early and Late Recovery Periods of Ischemic Stroke - E. S. Koroleva; N. G. Brazovskaya; L. A. Levchuk; S. D. Kazakov; N. Yu. Romadina; V. M. Alifirova (Neuroscience and Behavioral Physiology, 2021)

Contrasting Neoproterozoic and Mesozoic granitoids in Zaranda complex (Nigeria): insights into the distinct origins, tectonic settings and mineralization potential - Hafizullah Abba Ahmed; Lian-Xun Wang; Chang-Qian Ma; Mohammed I. M. Abdallsamed; Musa Bala Girei; Yu-Xiang Zhu; Victor Ikechukwu Vincent; Dlama Vandi Kamaunji; Liang Cao (International Journal of Earth Sciences, 2021)

State of enzymatic antioxidative system and heat resistance of wheat plantlets treated by combination of 24-epibrassinolide and NO donor - Yu. V. Karpets; M. A. Shkliarevskyi; V. A. Khripach; Yu. E. Kolupaev (Cereal Research Communications, 2021)

Assessment of the Tidal Current Energy Resources and the Hydrodynamic Impacts of Energy Extraction at the PuHu Channel in Zhoushan Archipelago, China - He Wu; Huaming Yu; Yizhou Fang; Qingwei Zhou; Fengxuan Zhuo; Ryan M. Kelly (Journal of Ocean University of China, 2021)

Circular dichroism and resonance Raman spectroscopies of bacteriochlorophyll b-containing LH1-RC complexes - Y. Kimura; T. Yamashita; R. Seto; M. Imanishi; M. Honda; S. Nakagawa; Y. Saga; S. Takenaka; L.-J. Yu; M. T. Madigan; Z.-Y. Wang-Otomo (Photosynthesis Research, 2021)

Effects of Acute Stress in Mice with 5-HT1A Receptors with Different Sensitivities to Chronic Activation by 8-OH-DPAT - E. M. Kondaurova; E. V. Antonov; E. Yu. Bazhenova; D. V. Bazovkina; V. S. Naumenko (Neuroscience and Behavioral Physiology, 2021)

Characteristics of Brain fMRI Responses to Motor Loads in Patients with Mild Posttraumatic Hemiparesis - G. N. Boldyreva; M. Yu. Yarets; E. V. Sharova; L. A. Zhavoronkova; S. V. Kuptsova; M. V. Chelyapina-Postnikova; E. L. Masherov; M. A. Kulikov; A. S. Smirnov; I. N. Pronin (Neuroscience and Behavioral Physiology, 2021)

Selection of Neuroprotective Therapy in Patients with Chronic Cerebral Ischemia Taking Account of the Synergism of Drug Interactions - O. A. Gromova; I. Yu. Torshin; M. V. Putilina; V. A. Semenov; K. V. Rudakov (Neuroscience and Behavioral Physiology, 2021)

A comparison of the holiday climate index:beach and the tourism climate index across coastal destinations in China - D D Yu; M. Rutty; D. Scott; S Li (International Journal of Biometeorology, 2021)

A new primer set for Clade I nosZ that recovers genes from a broader range of taxa - Bangzhou Zhang; C. Ryan Penton; Zhenhua Yu; Chao Xue; Qiongyun Chen; Zhangran Chen; Changsheng Yan; Qiang Zhang; Mengxin Zhao; John F. Quensen; James M. Tiedje (Biology and Fertility of Soils, 2021)

Spike Activity in the Ventromedial Nucleus of Rat Hypothalamus during Aging - K. Yu. Moiseev; A. A. Spirichev; L. G. Pankrasheva; A. S. Martyusheva; A. Yu. Abramova; P. M. Maslyukov (Bulletin of Experimental Biology and Medicine, 2021)

Dynamics of Antibodies to Various Antigens of the SARS-CoV-2 Coronavirus in Patients with Confirmed COVID-19 Infection - A. V. Aleshkin; L. I. Novikova; S. S. Bochkareva; S. Yu. Kombarova; Yu. S. Lebedin; A. M. Vorob’ev; E. R. Mekhtiev; E. R. Zul’karneev; A. I. Laishevtsev; A. V. Karaulov (Bulletin of Experimental Biology and Medicine, 2021)

Analysis of the Correlation between CD133 Expression on Human Colorectal Adenocarcinoma Cells HT-29 and Their Resistance to Chemotherapeutic Drugs - I. V. Kholodenko; Ya. S. Kim; A. M. Gisina; A. Yu. Lupatov; R. V. Kholodenko; K. N. Yarygin (Bulletin of Experimental Biology and Medicine, 2021)

Comparative Morphological Study of the Formation of Reparative Regenerate during Skin Wound Healing in Rats under the Effect of Drugs and Bone Marrow - R. K. Chailakhyan; E. S. Mishina; A. G. Grosheva; N. N. Vorob’eva; V. I. Khachiyants; Yu. M. Inshakov; Yu. V. Gerasimov; A. I. Kuralesova; I. L. Moskvina (Bulletin of Experimental Biology and Medicine, 2021)

Pathogenetic Therapy of Epidermolysis Bullosa: Current State and Prospects - I. I. Ryumina; K. V. Goryunov; D. N. Silachev; Yu. A. Shevtsova; V. A. Babenko; N. M. Marycheva; Yu. Yu. Kotalevskaya; V. V. Zubkov; G. T. Zubkov (Bulletin of Experimental Biology and Medicine, 2021)

Experimental Evaluation of Long-Term Toxic Effects of Methotrexate on Male Reproductive System - T. G. Borovskaya; Yu. A. Shchemerova; E. A. Bokhan; V. A. Grigor’eva; A. V. Vychuzhanina; M. E. Poluektova; V. E. Goldberg; A. M. Dygai (Bulletin of Experimental Biology and Medicine, 2021)

Age-Related Features of the Response of the Liver and Stem Cells during Modeling of Liver Cirrhosis - E. G. Skurikhin; M. A. Zhukova; E. S. Pan; N. N. Ermakova; O. V. Pershina; A. V. Pakhomova; O. D. Putrova; L. A. Sandrikina; V. A. Krupin; L. V. Kogai; T. Yu. Rebrova; S. A. Afanas’ev; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Extraction of Diagnostic Information on Brain Diseases by Analyzing Wavelet Spectra of Biomedical Signals - O. S. Sushkova; A. V. Gabova; L. A. Zhavoronkova; A. V. Karabanov; I. A. Kershner; A. A. Morozov; M. V. Sinkin; R. A. Tolmacheva; L. A. Chigaleychik; Yu. V. Obukhov (Biomedical Engineering, 2021)

In Silico Ventilation Within the Dose-Volume is Predictive of Lung Function Post-radiation Therapy in Patients with Lung Cancer - Yu Dong; H. Kumar; M. Tawhai; C. Veiga; A. Szmul; D. Landau; J. McClelland; L. Lao; K. S. Burrowes (Annals of Biomedical Engineering, 2021)
Lung cancer is a leading cause of death worldwide. Radiation therapy (RT) is one method to treat this disease. A common side effect of RT for lung cancer is radiation-induced lung damage (RILD) which leads to loss of lung function. RILD often compounds pre-existing smoking-related regional lung function impairment. It is difficult to predict patient outcomes due to large variability in individual response to RT. In this study, the capability of image-based modelling of regional ventilation in lung cancer patients to predict lung function post-RT was investigated. Twenty-five patient-based models were created using CT images to define the airway geometry, size and location of tumour, and distribution of emphysema. Simulated ventilation within the 20 Gy isodose volume showed a statistically significant negative correlation with the change in forced expiratory volume in 1 s 12-months post-RT ( p = 0.001, R = − 0.61). Patients with higher simulated ventilation within the 20 Gy isodose volume had a greater loss in lung function post-RT and vice versa. This relationship was only evident with the combined impact of tumour and emphysema, with the location of the emphysema relative to the dose-volume being important. Our results suggest that model-based ventilation measures can be used in the prediction of patient lung function post-RT.

Strengths and weaknesses in the long‐term sustainability of two sympatric seabreams ( Argyrops spinifer and Rhabdosargus haffara , S paridae) - Yu‐Jia Lin; Lotfi Rabaoui; Rommel H. Maneja; Abdu Rahiman Kambrath Pulikkoden; Panickan Premlal; Zahid Nazeer; Mohammad A. Qurban; Khaled Abdulkader; Perdana K. Prihartato; Ali M. Qasem; Nabil Fita; Ruben H. Roa‐Ureta (Journal of Fish Biology, 2021)
Argyrops spinifer and Rhabdosargus haffara are two sympatric seabream species making important contributions to fisheries landings in the western Arabian/Persian Gulf. We identified the strengths and weaknesses in the long‐term sustainability of A. spinifer and R. haffara stocks by integrating multiple sources of data, including fisheries catch and effort statistics, life history traits, scientific trawl surveys and historical length frequency distribution. Four strengths were identified in A. spinifer : wide distribution of juveniles, positive association to the network of de facto fishing exclusion areas created by hundreds of oil‐gas facilities, early maturation and the existence of large and old individuals. A. spinifer suffers from two potential weaknesses: slow growth rate and higher exploitation pressure on the small‐sized individuals. R. haffara , on the other hand, has a strength of having a short life span and a fast growth rate, characteristics that make it robust to unfavourable conditions. R. haffara suffers from two weaknesses: the lack of association to the oil and gas facilities, and the preference for nearshore shallow waters with stronger negative anthropogenic impacts. Identified strengths and weaknesses of these two sparids provided a preliminary assessment about their long‐term sustainability, as well as a roadmap about how to develop different management strategies to meet specific objectives.

Pseudomonas simiae WCS417: star track of a model beneficial rhizobacterium - Corné M. J. Pieterse; Roeland L. Berendsen; Ronnie de Jonge; Ioannis A. Stringlis; Anja J. H. Van Dijken; Johan A. Van Pelt; Saskia C. M. Van Wees; Ke Yu; Christos Zamioudis; Peter A. H. M. Bakker (Plant and Soil, 2021)
Background Since the 1980s, numerous mutualistic Pseudomonas spp. strains have been used in studies on the biology of plant growth-promoting rhizobacteria (PGPR) and their interactions with host plants. In 1988, a strain from the Pseudomonas fluorescens group, WCS417, was isolated from lesions of wheat roots growing in a take-all disease-suppressive soil. In subsequent trials, WCS417 limited the build-up of take-all disease in field-grown wheat and significantly increased wheat yield. In 1991, WCS417 was featured in one of the first landmark studies on rhizobacteria-induced systemic resistance (ISR), in which it was shown to confer systemic immunity in carnation ( Dianthus caryophyllus ) against Fusarium wilt. The discovery that WCS417 conferred systemic immunity in the model plant species Arabidopsis thaliana in 1996 incited intensive research on the molecular mechanisms by which PGPR promote plant growth and induce broad-spectrum disease resistance in plants. Since then, the strain name appeared in over 750 studies on beneficial plant-microbe interactions. Scope In this review, we will highlight key discoveries in plant-microbe interactions research that have emerged from over 30 years of research featuring WCS417 as a model rhizobacterial strain. WCS417 was instrumental in improving our understanding of the microbial determinants that are involved in root colonization and the establishment of mutually beneficial interactions with the host plant. The model strain also provided novel insight into the molecular mechanisms of plant growth promotion and the onset and expression of rhizobacteria-ISR. More recently, WCS417 has been featured in studies on host immune evasion during root colonization, and chemical communication in the rhizosphere during root microbiome assembly. Conclusions Numerous studies on the modes of action of WCS417 have provided major conceptual advances in our understanding of how free-living mutualists colonize the rhizosphere, modulate plant immunity, and promote plant growth. The concepts may prove useful in our understanding of the molecular mechanisms involved in other binary plant-beneficial microbe interactions, and in more complex microbial community contexts, such as the root microbiome.

Pentacyclic triterpene acid conjugated with mitochondria-targeting cation F16: Synthesis and evaluation of cytotoxic activities - Anna Yu. Spivak; Darya A. Nedopekina; Rinat R. Gubaidullin; Eldar V. Davletshin; Adis A. Tukhbatullin; Vladimir A. D’yakonov; Milyausha M. Yunusbaeva; Lilya U. Dzhemileva; Usein M. Dzhemilev (Medicinal Chemistry Research, 2021)

Combination of Muramylpeptides from Gram-Negative Bacteria Corrects Cyclophosphamide-Induced Disorders of Hematopoiesis and Spleen Cell Composition in Mice with B16 Melanoma - M. V. Kiselevskii; N. Yu. Anisimova; S. M. Sitdikova; F. V. Donenko; V. L. L’vov; O. V. Kalyuzhin; A. Yu. Nurtazina; A. V. Karaulov (Bulletin of Experimental Biology and Medicine, 2021)

Hyperglycemia and Some Aspects of Leukocyte Activation In Vitro - E. V. Mikhalchik; V. A. Lipatova; L. Yu. Basyreva; O. M. Panasenko; S. A. Gusev; V. I. Sergienko (Bulletin of Experimental Biology and Medicine, 2021)

Assessing the effects of climate variable and timescale selection on uncertainties in dryness/wetness trends in conterminous China - Tianxiao Ma; Yu Liang; Michael G. Sunde; Matthew K. Lau; Bo Liu; Mia M. Wu; Hong S. He (International Journal of Climatology, 2021)
Analysing dryness/wetness trends, which is typically achieved by examining drought indices, is an essential approach for assessing extreme climate events. However, since there are differences among studies in terms of selected climate variables and timescales used to calculate drought indices, there is uncertainty regarding the magnitude and direction of the dryness/wetness, trend even for the same region. We used 40 years weather station data (1970–2010) and studied the uncertainties of dryness/wetness trends in conterminous China. The effects of selected climate variables, timescales and their interaction on the dryness/wetness trends were quantified by comparing the Standardized Precipitation Index, Standardized Precipitation Evapotranspiration Index (SPEI) with the Thornthwaite equation and SPEI with the Penman–Monteith equation at 3‐, 12‐ and 24‐month timescales. The results indicated that (a) higher uncertainties occurred in relatively arid and humid regions; (b) timescale tended to exaggerate the effect of climate variables, even though its effect was substantially lower than climate variables; (c) relative humidity and precipitation were the primary climate variables affecting observed dryness/wetness trend uncertainties. Since the key climate variables changed depending on the selected timescale, the role of timescale should be further examined the Inner Mongolia and Northeast regions. In general, the study results suggest that the trend analysis of dryness/wetness should include the interaction of both climate variable and timescale selection, particularly when a single drought index is used to estimate the dryness/wetness trend in diverse regions.

Brain Bioelectrical Activity in Children with Acute Viral Encephalitis - V. B. Voitenkov; M. V. Sinkin; N. V. Skripchenko; E. V. Ekusheva; E. Yu. Gorelick; N. V. Marchenko; A. V. Shtekleyn; M. A. Bedova (Neuroscience and Behavioral Physiology, 2021)

Changes in the Expression of Steroidogenic Factor 1 (SF-1) in Neurons in the Ventromedial Nucleus of the Hypothalamus in Rats on Aging - K. Yu. Moiseev; A. A. Spirichev; P. A. Vishnyakova; A. D. Nozdrachev; P. M. Masliukov (Neuroscience and Behavioral Physiology, 2021)

Dyslexia as a Multifactorial Disorder - S. Yu. Surushkina; E. A. Yakovenko; L. S. Chutko; M. D Didur (Neuroscience and Behavioral Physiology, 2021)

The Attractive Geosites and Perspective of Geotourism Development in the Chorna Tysa River Basin (Ukrainian Carpathians) - S. Yu. Bortnyk; T. M. Lavruk; O. V. Kovtoniuk; I. V. Kravchuk (Geoheritage, 2021)

Study of Hematological Parameters and Morphometric Indices of Erythrocytes in Rats Exposed to Calcium Oxide Nanoparticles - M. A. Zemlyanova; N. V. Zaitseva; A. M. Ignatova; M. S. Stepankov; L. I. Toropov; Yu. V. Kol’dibekova (Bulletin of Experimental Biology and Medicine, 2021)

Pharmacological Correction of Cisplatin-Induced Hemostatic Disorders - M. V. Filonova; E. P. Fedorova; A. A. Churin; L. Yu. Kotlovskaya; M. A. Solov’ev; V. V. Udut (Bulletin of Experimental Biology and Medicine, 2021)

Effect of Azithromycin on Myocardial Resistance to Ischemia/Reperfusion in Systemic Inflammatory Response Syndrome and Alimentary Obesity - Yu. Yu. Borshchev; S. M. Minasian; I. Yu. Burovenko; V. Yu. Borshchev; E. S. Protsak; O. V. Borshcheva; M. M. Galagudza (Bulletin of Experimental Biology and Medicine, 2021)

Devices for Sealing Polymer Containers with Blood and Its Components - A. G. Gudkov; V. Yu. Leushin; I. A. Sidorov; S. V. Agasieva; I. O. Porokhov; A. V. Chechetkin; M. I. Lazarenko; N. A. Vetrova; G. A. Gudkov; V. G. Tikhomirov (Biomedical Engineering, 2021)

Electric Field Stimulation for the Functional Assessment of Isolated Dorsal Root Ganglion Neuron Excitability - Ian M. Berke; Tom M. McGrath; J. Jordan Stivers; Chang Gui; Marcos N. Barcellona; Matthew G. Gayoso; Simon Y. Tang; Yu-Qing Cao; Munish C. Gupta; Lori A. Setton (Annals of Biomedical Engineering, 2021)

Biogeography and co‐occurrence patterns of bacterial generalists and specialists in three subtropical marine bays - Yuanyuan Mo; Wenjing Zhang; David M. Wilkinson; Zheng Yu; Peng Xiao; Jun Yang (Limnology and Oceanography, 2021)
Recent research has greatly expanded our understanding of microbial metacommunities in aquatic ecosystems. However, patterns at the mesoscale are still poorly understood. We present the first simultaneous analyses of the biogeography and co‐occurrence patterns of generalists and specialists marine bacteria from three subtropical bays of China and test for signals of ecological processes (i.e., stochastic and deterministic processes) in biogeography and community assembly. Results showed that compared to specialists, bacterial generalists were less diverse, and were more widely dispersed in the three subtropical bays. Network analysis indicated that both habitat generalists and specialists showed non‐random co‐occurrence patterns, and specialists had a more complex co‐occurrence pattern than generalists. Further, specialists co‐occurrence network exhibited distinct robust structure compared to generalists, indicating that the both taxa showed different network stability. Our null models indicated that the generalists and specialists were primarily shaped by deterministic processes ‐ such as variable selection. However, deterministic processes played a greater role in the community variation of specialists (84%) than generalists (56%). The study has broadened our understanding of generalists and specialists distribution in the bacterioplankton; further revealing the dominant roles of similar ecological mechanisms (deterministic processes) in shaping the community assembly. The differences in complex and stable co‐occurrence pattern between generalists and specialists could be driven by deterministic processes. By considering the roles of species traits and ecological processes, we provide a deeper mechanistic understanding of bacterial biogeographical and co‐existence patterns.

Genetic diversity and life‐history traits of bonefish Albula spp. from the Red Sea - Collin T. Williams; Ashlie J. McIvor; Elizabeth M. Wallace; Yu‐Jia Lin; Michael L. Berumen (Journal of Fish Biology, 2021)
The management of bonefishes Albula spp. has been hindered by unresolved species distributions and a general lack of life‐history information. This study provides the first genetic species identifications of Albula spp. from the northern Indian Ocean. The roundjaw bonefish Albula glossodonta was documented in the Red Sea, and the smallscale bonefish A. oligolepis was identified in the Gulf of Aden with no evidence supporting sympatry. Estimates of genetic differentiation indicate three closely related lineages of A. glossodonta in the Red Sea, Indian Ocean and Pacific Ocean (Red Sea‐Pacific Ocean, F st = 0.295; Red Sea‐Seychelles, F st = 0.193; Pacific Ocean‐Seychelles, F st = 0.141). In addition, the authors provide the first life‐history information of Albula spp. in the Indian Ocean. Age‐based growth models of A. glossodonta from the Red Sea demonstrated statistically significant differences compared to previously published data from the Pacific Ocean. Spawning activity during winter months was derived from gonado‐somatic index values of A. glossodonta from the Red Sea and corresponded with spawning seasonality previously documented for the species in the Pacific Ocean. The results of this study aid in refining biogeographical uncertainties of Albula spp. and illustrate the importance of collecting regional growth information for subsequent management of A. glossodonta .

Warming Iron-Limited Oceans Enhance Nitrogen Fixation and Drive Biogeographic Specialization of the Globally Important Cyanobacterium Crocosphaera - Nina Yang; Carlin A. Merkel; Yu-An Lin; Naomi M. Levine; Nicholas J. Hawco; Hai-Bo Jiang; Ping-Ping Qu; Michelle A. DeMers; Eric A. Webb; Fei-Xue Fu; David A. Hutchins (Frontiers in Marine Science, 2021)
Primary productivity in the nutrient-poor subtropical ocean gyres depends on new nitrogen inputs from nitrogen fixers that convert inert dinitrogen gas into bioavailable forms. Temperature and iron (Fe) availability constrain marine nitrogen fixation, and both are changing due to anthropogenic ocean warming. We examined the physiological responses of the globally important marine nitrogen fixer, Crocosphaera watsonii across its full thermal range as a function of iron availability. At the lower end of its thermal range, from 22 to 27°C, Crocosphaera growth, nitrogen fixation, and Nitrogen-specific Iron Use Efficiencies (N-IUEs, mol N fixed hour –1 mol Fe –1 ) increased with temperature. At an optimal growth temperature of 27°C, N-IUEs were 66% higher under iron-limited conditions than iron-replete conditions, indicating that low-iron availability increases metabolic efficiency. However, Crocosphaera growth and function decrease from 27 to 32°C, temperatures that are predicted for an increasing fraction of tropical oceans in the future. Altogether, this suggests that Crocosphaera are well adapted to iron-limited, warm waters, within prescribed limits. A model incorporating these results under the IPCC RCP 8.5 warming scenario predicts that Crocosphaera N-IUEs could increase by a net 47% by 2100, particularly in higher-latitude waters. These results contrast with published responses of another dominant nitrogen fixer ( Trichodesmium ), with predicted N-IUEs that increase most in low-latitude, tropical waters. These models project that differing responses of Crocosphaera and Trichodesmium N-IUEs to future warming of iron-limited oceans could enhance their current contributions to global marine nitrogen fixation with rates increasing by ∼91 and ∼22%, respectively, thereby shifting their relative importance to marine new production and also intensifying their regional divergence. Thus, interactive temperature and iron effects may profoundly transform existing paradigms of nitrogen biogeochemistry and primary productivity in open ocean regimes.

In vitro plant regeneration from mature embryos of amphidiploid spelt Triticum spelta L. - A.V. Kyriienko; N. L. Shcherbak; M. V. Kuchuk; M. F. Parii; Yu V. Symonenko (In Vitro Cellular & Developmental Biology - Plant, 2021)

Use of a flexible chamber to measure stem respiration - Eike M. Esders; Otto Klemm; Bettina Breuer; Yen-Jen Lai; Jui-Chu Yu; I-Ling Lai (Trees, 2021)

Psychotic Disorders in the Veterans of Local Wars - A. M. Reznik; T. S. Syunyakov; D. V. Shcherbakov; Yu. L. Martynyuk (Neuroscience and Behavioral Physiology, 2021)

The Novel Coronavirus Infection (COVID-19) and Nervous System Involvement: Mechanisms of Neurological Disorders, Clinical Manifestations, and the Organization of Neurological Care - E. I. Gusev; M. Yu. Martynov; A. N. Boyko; I. A. Voznyuk; N. Yu. Latsh; S. A. Sivertseva; N. N. Spirin; N. A. Shamalov (Neuroscience and Behavioral Physiology, 2021)

The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish - Si-Lan Han; Yan Liu; Samwel M. Limbu; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2021)

An injectable microparticle formulation for the sustained release of the specific MEK inhibitor PD98059: in vitro evaluation and pharmacokinetics - Youssef W. Naguib; Brittany E. Givens; Giang Ho; Yang Yu; Shun-Guang Wei; Robert M. Weiss; Robert B. Felder; Aliasger K. Salem (Drug Delivery and Translational Research, 2021)

Chondrogeneic Potential of MSC from Different Sources in Spheroid Culture - A. V. Tsvetkova; I. V. Vakhrushev; Yu. B. Basok; A. M. Grigor’ev; L. A. Kirsanova; A. Yu. Lupatov; V. I. Sevastianov; K. N. Yarygin (Bulletin of Experimental Biology and Medicine, 2021)

Specific Features of Intracellular Signal Transduction in the Regulation of Functions of Neural Stem Cells and Committed Neuronal Progenitors - G. N. Zyuz’kov; L. A. Miroshnichenko; T. Yu. Polyakova; V. V. Zhdanov; E. V. Simanina; L. A. Stavrova; M. G. Danilets (Bulletin of Experimental Biology and Medicine, 2021)

Immunomodulating Properties of Humic Acids Extracted from Oligotrophic Sphagnum magellanicum Peat - E. S. Trofimova; M. V. Zykova; M. G. Danilets; A. A. Ligacheva; E. Yu. Sherstoboev; A. V. Tsupko; D. A. Mikhalyov; M. V. Belousov (Bulletin of Experimental Biology and Medicine, 2021)

Effect of a New Lithium Preparation on the Behavior of CBA/CaLac Mice in an Experimental Conflict Model - M. A. Korolev; P. G. Madonov; L. N. Rachkovskaya; N. I. Suslov; A. V. Shurlygina; E. E. Rachkovskii; M. V. Robinson; A. A. Kotlyarova; T. V. Popova; T. N. Povet’eva; O. G. Afanas’eva; Yu. V. Nesterova; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Archaeological and experimental studies of splintered pieces in the Central Asian Upper Paleolithic - K. A. Kolobova; V. M. Kharevich; A. V. Kharevich; A. Yu. Fedorchenko; E. N. Bocharova; R. Kurbanov; D. Flas; A. I. Krivoshapkin; J. W. Olsen (Archaeological and Anthropological Sciences, 2021)

Interaction of the Lofoten Vortex with a Satellite Cyclone - T. V. Belonenko; V. A. Zinchenko; A. M. Fedorov; M. V. Budyansky; S. V. Prants; M. Yu. Uleysky (Pure and Applied Geophysics, 2021)

Light Adaptation of Retinal Rods, Adaptation Memory, and Afterimages - A. Yu. Rotov; L. A. Astakhova; M. L. Firsov; V. I. Govardovskii (Neuroscience and Behavioral Physiology, 2021)

Polymorphism of the APOE Gene and Markers of Brain Damage in the Outcomes of Severe Traumatic Brain Injury in Children - E. G. Sorokina; Zh. B. Semenova; N. S. Averianova; O. V. Karaseva; E. N. Arsenieva; V. I. Luk’yanov; V. P. Reutov; A. Yu. Asanov; L. M. Roshal; V. G. Pinelis (Neuroscience and Behavioral Physiology, 2021)

Impairments to Executive Functions in Children with Emotional and Behavioral Dysregulation - L. S. Chutko; S. Yu. Surushkina; E. A. Yakovenko; T. I. Anisimova; A. V. Sergeev; M. D. Didur (Neuroscience and Behavioral Physiology, 2021)

A study of kudurs used by wild animals located on the water sources high in REE content in the Caucasus Nature Reserve - A. M. Panichev; S. A. Trepet; I. Yu. Chekryzhov; I. V. Seryodkin; E. A. Vakh; R. A. Makarevich; T. G. Eskina; K. V. Bibina; T. A. Stolyarova; E. I. Mitina; V. V. Ivanov; D. S. Ostapenko; et al. (Environmental Geochemistry and Health, 2021)

Analgesic Action of Invasive Carboxytherapy: Mechanisms and Applications - N. M. Seredynska; S. M. Drogovoz; E. G. Shchokina; L. B. Ivantsyk; Yu. V. Stoletov; A. L. Shtroblya; I. V. Kireyev (Neurophysiology, 2021)

Comparative Morphological Characteristics of the Results of Implantation of Decellularized and Recellularized Porcine Skin Scaffolds - A. S. Sotnichenko; I. V. Gilevich; K. I. Melkonyan; Y. A. Yutskevich; T. V. Rusinova; A. V. Karakulev; S. B. Bogdanov; V. A. Aladina; Yu. A. Belich; S. E. Gumenyuk; D. I. Ushmarov; I. M. Bykov; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Destruction of Renal Concretions with Electrolytic Glow Discharge Plasma - S. Kh. Ali; Kh. M. Ali; E. A. Bezrukov; S. V. Belov; Yu. K. Danyleiko; A. B. Egorov; V. A. Sidorov; V. B. Tsvetkov (Biomedical Engineering, 2021)

Applicability of 3D-Printed Polymer Compensators for Modulated Electron Radiotherapy (MERT) - A. A. Grigorieva; A. A. Bulavskaya; D. A. Belousov; I. A. Miloichikova; Yu. M. Cherepennikov; S. G. Stuchebrov (Biomedical Engineering, 2021)

Mutation H(M202)L does not lead to the formation of a heterodimer of the primary electron donor in reaction centers of Rhodobacter sphaeroides when combined with mutation I(M206)H - Anton M. Khristin; Alexey A. Zabelin; Tatiana Yu. Fufina; Ravil A. Khatypov; Ivan I. Proskuryakov; Vladimir A. Shuvalov; Anatoly Ya. Shkuropatov; Lyudmila G. Vasilieva (Photosynthesis Research, 2020)

A review of the Chinese monotypic genus Melliodendron (Styracaceae), with a new synonym of M. xylocarpum - Xue-Hui Wu; Rui Zhang; Timothy M. A. Utteridge; Yu-Lin Liu; Guang-Yao Yang; Ming Tang (Kew Bulletin, 2020)

Breast tumour cell subpopulations with expression of the MYC and OCT4 proteins - N. V. Litviakov; V. A. Bychkov; M. N. Stakheeva; M. K. Ibragimova; M. M. Tsyganov; K. A. Gaptulbarova; L. A. Tashireva; L. N. Bondar; E. Yu. Garbukov; E. M. Slonimskaya (Journal of Molecular Histology, 2020)

Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity - Justin Darcy; Yimin Fang; Samuel McFadden; Matthew D. Lynes; Luiz O. Leiria; Jonathan M. Dreyfuss; Valerie Bussburg; Vladimir Tolstikov; Bennett Greenwood; Niven R. Narain; Michael A. Kiebish; Andrzej Bartke; et al. (GeroScience, 2020)

An Assessment of Inter-Observer Agreement in Water Source Classification and Sanitary Risk Observations - Joseph Okotto-Okotto; Peggy Wanza; Emmah Kwoba; Weiyu Yu; Mawuli Dzodzomenyo; S. M. Thumbi; Diogo Gomes da Silva; Jim A. Wright (Exposure and Health, 2020)
Sanitary risk inspection, an observation protocol for identifying contamination hazards around water sources, is promoted for managing rural water supply safety. However, it is unclear how far different observers consistently identify contamination hazards and consistently classify water source types using standard typologies. This study aimed to quantify inter-observer agreement in hazard identification and classification of rural water sources. Six observers separately visited 146 domestic water sources in Siaya County, Kenya, in wet and dry seasons. Each observer independently classified the source type and conducted a sanitary risk inspection using a standard protocol. Water source types assigned by an experienced observer were cross-tabulated against those of his colleagues, as were contamination hazards identified, and inter-observer agreement measures calculated. Agreement between hazards observed by the most experienced observer versus his colleagues was significant but low (intra-class correlation = 0.49), with inexperienced observers detecting fewer hazards. Inter-observer agreement in classifying water sources was strong (Cohen’s kappa = 0.84). However, some source types were frequently misclassified, such as sources adapted to cope with water insecurity (e.g. tanks drawing on both piped and rainwater). Observers with limited training and experience thus struggle to consistently identify hazards using existing protocols, suggesting observation protocols require revision and their implementation should be supported by comprehensive training. Findings also indicate that field survey teams struggle to differentiate some water source types based on a standard water source classification, particularly sources adapted to cope with water insecurity. These findings demonstrate uncertainties underpinning international monitoring and analyses of safe water access via household surveys.

Investigating the associations of glycemic load and glycemic index with lung cancer risk in the Southern Community Cohort Study - Xiang Shu; Danxia Yu; Xiao-ou Shu; Heather M. Munro; Wei Zheng; William J. Blot (Cancer Causes & Control, 2020)

Verbal memory and hippocampal volume predict subsequent fornix microstructure in those at risk for Alzheimer’s disease - Junhong Yu; Tatia M. C. Lee (Brain Imaging and Behavior, 2020)
While strong cross-sectional evidence supported the use of fornix microstructure as a marker for detecting Alzheimer’s disease (AD), longitudinal data remains inconclusive on the sequential nature of fornix microstructure abnormalities and AD progression. An unequivocal longitudinal relationship between fornix microstructure and markers of AD progression –memory impairment and hippocampal atrophy, must be established to validate fornix microstructure as a marker of AD progression. We included 115 participants from the Alzheimer’s Disease Neuroimaging Initiative across the non-demented AD spectrum— defined as those who had at least one AD risk marker at baseline (e.g., mild cognitive impairment (MCI) due to AD diagnosis, amyloid or ApoE4 positivity) and/or ‘cognitively normal individuals who converted to MCI due to AD or AD, with structural and diffusion tensor imaging scans at baseline and two years follow-up. Hippocampal volumes (HV), fractional anisotropy (FA) and mean diffusivity (MD) in the fornix were extracted. Memory was indexed via composite scores of verbal memory tests. Structural equation models tested the bidirectional cross-lagged effects of fornix microstructure, memory, and HV. Impaired memory and smaller HV at baseline significantly predicted worse fornix microstructure (decreased FA and increased MD) two years later. Baseline fornix microstructure was not associated with subsequent changes in memory and HV. Fornix microstructure is compromised likely at a later stage, where significant decline in memory and hippocampal atrophy have occurred. This limits the utility of fornix microstructure in the early detection of AD. Our findings inform the possible pathophysiology and refined the use of AD neural markers.

Study of Immunotropic Properties of Water-Soluble Polysaccharides Isolated from Conium maculatum Grass - A. A. Ligacheva; E. Yu. Sherstoboev; M. G. Danilets; E. S. Trofimova; S. V. Krivoshchekov; A. M. Gur’ev; T. V. Bulgakov; N. V. Kudashkina; A. G. Miroshnichenko; M. V. Belousov (Bulletin of Experimental Biology and Medicine, 2020)

Estimation of Absolute Bioavailability of the Chemical Substance of the Anti-Smallpox Preparation NIOCH-14 in Mice - O. Yu. Mazurkov; L. N. Shishkina; N. I. Bormotov; M. O. Skarnovich; O. A. Serova; N. A. Mazurkova; A. A. Chernonosov; A. Ya. Tikhonov; B. A. Selivanov (Bulletin of Experimental Biology and Medicine, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Diversity of gut microbiomes in marine fishes is shaped by host‐related factors - Qi Huang; Ronia C. Sham; Yu Deng; Yanping Mao; Chunxiao Wang; Tong Zhang; Kenneth M. Y. Leung (Molecular Ecology, 2020)
Microorganisms in the gastrointestinal tract of animals play vital roles in food digestion, homeostasis and immune response regulation. Globally, there are 33,700 fish species, representing almost half of all vertebrate diversity and a wide range of physiologies, ecologies and life histories. To investigate gut microbiomes with high coverage, we performed 16S rRNA gene amplicon sequencing with 115 samples of 20 common marine fish species. The fish gut microbiome is a remarkably simple community with low microbial diversity (a maximum of 300 amplicon sequence variants only) and has up to 70% of unknown species in some fish species. The gut microbial community structure was significantly shaped by the combined influence of host‐associated factors, including the fish taxon ( p R 2 = 0.16, ω 2 = 0.04), feeding habit ( p R 2 = 0.06, ω 2 = 0.02) and trophic level ( p R 2 = 0.04, ω 2 = 0.01), although the influence was subtle with a small effect size. The core gut microbiomes of different feeding habits were also previously discovered in animal‐associated and corresponding habitat samples. Certain energy metabolism pathways were enriched in herbivore/omnivore and zooplanktivore/zoobenthivore fishes, whereas lipid metabolism and glycan metabolism were enriched in zoobenthivore/piscivore fishes. Moreover, substantial taxonomic variability was found between the gut microbiomes of fish and animals, indicated by their low degree of shared microbiota. The data and observations reported herein pave the way for further investigations on the co‐evolution of fish gut microbiomes and their hosts, the physiological functions of gut microorganisms and the development of probiotics for improving the nutrition and health of aquaculture fish species.

U-Pb dating of detrital zircons from basal Post Paleoproterozoic metasediments in the Subpolar and Polar Urals: evidence for a Cryogenian, not Mesoproterozoic age - A. M. Pystin; Yu. I. Pystina; N. S. Ulyasheva; O. V. Grakova (International Geology Review, 2020)