Functional analysis of HADH c.99C>G shows that the variant causes the proliferation of pancreatic islets and leu-sensitive hyperinsulinaemia - Wu Long; Yue-Bing Wang; Peng-Fei Qu; Lin Ma; Si-Jie Wei; Yan-Mei Xi; Jin-Liang Du; Xue Tang; Kai Liu; Yu-Hua Li; Pu-Ping Lei (Journal of Genetics, 2022)

Truncated analog Brevinin2-CE-N26V5K: Revelation the Augmentation of Antimicrobial Activity - Yi Zhao; Xiao-yan Wang; Yan Sun; Zhi Li; Tao Liu; Qing-mei Liu; Jingyi Chen (World Journal of Microbiology and Biotechnology, 2022)

Aluminum-activated Malate Transporter 12 is involved in restricting root-to-shoot Cl− transport in Arabidopsis under Cl−-salt stress - Rui-Wen Liu; Jian-Zhen Yuan; Xiao-Yu Li; Yan-Nong Cui; Mei-Mei Cai; Zi-Hua He; Qing Ma (Plant and Soil, 2022)

Identification of QTLs and a putative candidate gene involved in rhizome enlargement of Asian lotus (Nelumbo nucifera) - Yanling Liu; Heyun Song; Minghua Zhang; Dong Yang; Xianbao Deng; Heng Sun; Juan Liu; Mei Yang (Plant Molecular Biology, 2022)

Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia - Kang-Wei Qian; Yun-Yun Li; Xiao-Hua Wu; Xue Gong; Ai-Lin Liu; Wen-Hao Chen; Zhe Yang; Ling-Jie Cui; Yun-Feng Liu; Yuan-Yuan Ma; Chen-Xi Yu; Furong Huang; et al. (Neuroscience Bulletin, 2022)

Effects of human enclosure and farming activities on heavy metals in sediments/soils of the coastal reclamation areas in the Yangtze Estuary - Junfeng Mei; Jinpu Jia; Chunjuan Bi; Jiping Liu; Yongsheng Zeng; Zhenlou Chen (Journal of Soils and Sediments, 2022)

TLR9/FCRL3 regulates B cell viability, apoptosis, and antibody and IL-10 production through ERK1/2, p38, and STAT3 signaling pathways - Qi-bing Liu; Ren-hui Zhou; Chong-mei Liu (In Vitro Cellular & Developmental Biology - Animal, 2022)

Morphological characteristics of rock fissure networks and the main factors affecting their soil nutrients and enzyme activities in Guizhou Province, China - Mei-quan Wang; Qing-wei Guan; Zong-sheng Huang; Jia-hao Zhao; Zheng-ji Liu; Hao Zhang; Xun-wen-qian Bao; Lei Wang; Yu-qian Ye (Journal of Mountain Science, 2022)

Mice lacking DCAF2 in placenta die at the gastrulation stage - Man Yang; Mei Liu; Zongting Wang; Cong Zhang (Cell and Tissue Research, 2022)

FOSL2 deficiency delays nonalcoholic steatohepatitis progression by regulating LY6D-mediated NLRP3 activation - Pei-Xin Hu; Mei-Yan Sheng; Yan-Ping Liu; Chun-Qing Zhang (Human Cell, 2022)

Three types of pulsed signal trains emitted by Indo-Pacific humpback dolphins (Sousa chinensis) in Beibu Gulf, South China Sea - Xiao-yan Wang; Ying Jiang; Zong-wei Liu; Chun-mei Yang; Bing-yao Chen; Lian-gang Lü (Frontiers in Marine Science, 2022)
Pulsed signal trains comprising clicks, buzzes, and burst-pulses play important roles in the life activities of odontocetes, but they have not been distinguished in Indo-Pacific humpback dolphins. Underwater vocalizations of this species were recorded from 27 September to 2 October 2019 in the Beibu Gulf, South China Sea. Pulsed signal trains were detected with variations in the pulsed signal number (range of 6–76), mean inter-pulse interval (IPIs_m: 0.1–315 ms), and mean duration (D ranged from tens to thousands of milliseconds). Principal component analysis and hierarchical cluster analysis based on six acoustic parameters in the pulsed signal trains identified three categories of trains designated as clicks, burst-pulses, and buzzes. Buzzes and burst-pulses (different from those described in previous research) were detected for the first time in Indo-Pacific humpback dolphins in China. The results indicated that the IPIs_m was longest for clicks but shortest for buzzes, and the D values were longer for both clicks and burst-pulses than buzzes. The three train types could be identified based on the IPIs_m, with threshold values of 4.9 and 15.5 ms. The significant variations in the three vocalization types were related to surface behaviors, and buzzes could have a special function in foraging by this species, thereby requiring further research. These findings may facilitate future quantitative evaluations of the echolocation performance in wild Indo-Pacific humpback dolphins and provide important guidance regarding acoustic observations and the identification of this species.

Using Genetic Algorithm and Particle Swarm Optimization BP Neural Network Algorithm to Improve Marine Oil Spill Prediction - Xueyan Cheng; Xupeng Hu; Zhenzhen Li; Chuanhui Geng; Jiaxing Liu; Mei Liu; Baikang Zhu; Qian Li; Qingguo Chen (Water, Air, & Soil Pollution, 2022)

Quick mapping and characterization of a co-located kernel length and thousand-kernel weight-related QTL in wheat - Xiangru Qu; Cong Li; Hang Liu; Jiajun Liu; Wei Luo; Qiang Xu; Huaping Tang; Yang Mu; Mei Deng; Zhien Pu; Jun Ma; Qiantao Jiang; et al. (Theoretical and Applied Genetics, 2022)

Rapid Characterization of Landslide-Debris Flow Chains of Geologic Hazards Using Multi-method Investigation: Case Study of the Tiejiangwan LDC - Kun He; Bo Liu; Xiewen Hu; Ruichen Zhou; Chuanjie Xi; Guotao Ma; Mei Han; You Li; Gang Luo (Rock Mechanics and Rock Engineering, 2022)

The contribution of nirK gene-containing thaumarchaea to denitrification and N2O production across coastal sediment and terrestrial ecosystems - Bing Han; Si-Yi Liu; Li-Li Han; Xiao-Tong Song; Liu-Ying Mo; Li-Mei Zhang (Journal of Soils and Sediments, 2022)

Temporal specificity of IL-6 knockout in enhancing the thermogenic capability of brown adipose tissue - Mei Dong; Cheng Gao; Yanxin Jia; Weijia Xu; Yan Liu; Xin Wen; Qingxin Liu; Hai Lin; Haifang Li (Journal of Physiology and Biochemistry, 2022)

The safety degree evaluation of marine biodiversity in China - Xiu-Mei Fu; Wan-Yu Wu; Fang Yang; Shan-Shan Jiang; Shi-Qi Wang; Xiao-Yan Li; Hui-Ying Tang; Ying Liu; Chang-Yun Wang (Journal of Coastal Conservation, 2022)

Case series of congenital pseudarthrosis of the tibia unfulfilling neurofibromatosis type 1 diagnosis: 21% with somatic NF1 haploinsufficiency in the periosteum - Yu Zheng; Guanghui Zhu; Yaoxi Liu; Weihua Zhao; Yongjia Yang; Zhenqing Luo; Yuyan Fu; Haibo Mei; Zhengmao Hu (Human Genetics, 2022)

Characteristics and influencing factors of energy consumption in Chinese rural households - Xiaowei Ma; Dandan Liu; Danni Chen; Mei Wang; Chuandong Li (Environmental Science and Pollution Research, 2022)

Characteristics of subway excavation in soft soil and protective effects of partition wall on the historical building and pile foundation building - Meng Han; Zhe Li; Guoxiong Mei; Xiaohua Bao; Jinqing Jia; Lulu Liu; Youyun Li (Bulletin of Engineering Geology and the Environment, 2022)

Task modulates the orthographic and phonological representations in the bilateral ventral Occipitotemporal cortex - Jing Qu; Yingdan Pang; Xiaoyu Liu; Ying Cao; Chengmei Huang; Leilei Mei (Brain Imaging and Behavior, 2022)

Evansella halocellulosilytica sp. nov., an alkali-halotolerant and cellulose-dissolving bacterium isolated from bauxite residue - Guo-Hong Liu; Manik Prabhu Narsing Rao; Qian-Qian Chen; Jian-Mei Che; Huai Shi; Bo Liu; Wen-Jun Li (Extremophiles, 2022)

The effects of dietary fermented wheat bran polysaccharides on mucosal and serum immune parameters, hepatopancreas antioxidant indicators, and immune-related gene expression of common carp (Cyprinus carpio) juveniles - Rui-Fang Wang; Yuan Wang; Jun Zhang; Mei-Qi Weng; Yu-Hui Liu; Qiu-Yan Cheng; Min Song; Yan-Ping Yang; Xiao-Ping An; Jing-Wei Qi (Aquaculture International, 2022)

Coronavirus transmissible gastroenteritis virus antagonizes the antiviral effect of the microRNA miR-27b via the IRE1 pathway - Changlin Wang; Mei Xue; Peng Wu; Honglei Wang; Zhongqing Liu; Guangzheng Wu; Pinghuang Liu; Keliang Wang; Wanhai Xu; Li Feng (Science China Life Sciences, 2022)

Pharmacological activation of estrogenic receptor G protein-coupled receptor 30 attenuates angiotensin II-induced atrial fibrosis in ovariectomized mice by modulating TGF-β1/smad pathway - Da Liu; Yinge Zhan; Katsushige Ono; Yajuan Yin; Le Wang; Mei Wei; Lishuang Ji; Mei Liu; Gang Liu; Xin Zhou; Mingqi Zheng (Molecular Biology Reports, 2022)

Effects of nitrogen addition on the concentration and composition of soil-based dissolved organic matter in subtropical Pinus taiwanensis forests - Xiaochun Yuan; Juyan Cui; Kaimiao Lin; Cheng-Chung Liu; Jiacong Zhou; Qiufang Zhang; Quanxin Zeng; Lianzuan Wu; Yue Wu; Kongcan Mei; Huiying Lin; Huan Xie; et al. (Journal of Soils and Sediments, 2022)

Experimental and numerical investigation on hydrological characteristics of extensive green roofs under the influence of rainstorms - Jun Wang; Ankit Garg; Ning Liu; Deqiang Chen; Guoxiong Mei (Environmental Science and Pollution Research, 2022)

Experimental investigation on mechanical performance and failure modes of shale interbedded with sandstone under triaxial compression - Xiangchao Sheng; Lei Yang; Jie Mei; Xujin Ma; Qing Liu; Jinhui Chen (Bulletin of Engineering Geology and the Environment, 2022)

Vocalization of Bryde's whales ( Balaenoptera edeni ) in the Beibu Gulf, China - Zhi‐Tao Wang; Peng‐Xiang Duan; Mo Chen; Zhi‐Gang Mei; Xiao‐Dong Sun; Zhi‐Wen Nong; Mei‐Han Liu; Tomonari Akamatsu; Ke‐Xiong Wang; Ding Wang (Marine Mammal Science, 2022)
The presence of Bryde's whales ( Balaenoptera edeni ) in the Beibu Gulf, China has been reported since 2016. In the current study, in situ Bryde's whale vocalizations were recorded. Bouts of frequency modulated repetitive and diversified calls were recorded. Repetitive calls were recorded when 1–3 whales were present within 2 km of the boat and were probably emitted by a single whale and functioned as contact calls. Repetitive calls were divided into biphonation downswept tonals and downswept tonals. Diversified calls were recorded when 4–7 whales were present within 2 km of the boat and were probably associated with acoustic exchanges between or among conspecifics. Diversified calls occasionally contained inflection points, frequency jumps, and break point features. The frequency band of Bryde's whale vocalizations overlapped highly with background noise. Most vocalizations in the current study were different than those previously reported for this species. Therefore, the findings of this study provide more information on the known acoustic repertoire of Bryde's whales and provide a basis for noninvasive monitoring of Bryde's whale with passive acoustic methods and for developing mitigation and conservation protocols to ensure their future viability.

Cadinane-type sesquiterpenes with potential anti-inflammatory and anti-HIV activities from the stems and leaves of Mappianthus iodoides - Yan-Ping Liu; Xiao-Mei Yu; Ze-Hua Qiao; Bo Jiang; Lan Xie; Hao-Xuan Tang; Xiao Liang; Yan-Hui Fu (Natural Product Research, 2022)

Liamocin overproduction by the mutants of Aureobasidium melanogenum 9–1 for effectively killing spores of the pathogenic fungi from diseased human skin by Massoia lactone - Zhu Wang; Mei Zhang; Zhe Chi; Guang-Lei Liu; Zhen-Ming Chi (World Journal of Microbiology and Biotechnology, 2022)

Sex determination mechanisms and sex control approaches in aquaculture animals - Xi-Yin Li; Jie Mei; Chu-Tian Ge; Xiao-Li Liu; Jian-Fang Gui (Science China Life Sciences, 2022)

SWI2/SNF2 chromatin remodeling ATPases SPLAYED and BRAHMA control embryo development in rice - Qian Xun; Min Mei; Ye Song; Chenyu Rong; Jiajun Liu; Tianhui Zhong; Yanfeng Ding; Chengqiang Ding (Plant Cell Reports, 2022)

Establishment and optimization of PEG-mediated protoplast transformation in the microalga Haematococcus pluvialis - Chunli Guo; Muhammad Anwar; Rui Mei; Xinyi Li; Di Zhao; Yanan Jiang; Jieyi Zhuang; Chen Liu; Chaogang Wang; Zhangli Hu (Journal of Applied Phycology, 2022)
Genetic manipulation of Haematococcus pluvialis is difficult because of the lack of a stable and convenient transformation system. The pH124-EGFP-Ble vector containing ble as a selective gene and EGFP as a reporter gene was constructed and employed for effective transformation. H. pluvialis protoplasts were obtained by treating with cellulase and macerozeme. Then polyethylene glycol-mediated transformation was established by incubating the protoplast with the vector. To improve the transformation efficiency of H. pluvialis protoplasts, the transformation system was optimized in consideration of different influencing factors, including zeomycin concentration, growth stage, amount of transformed vector, linearization of the vector, and duration of low-intensity illumination. The integration and expression of ble and EGFP was confirmed in the transformants. Moreover, the optimal combination for protoplast transformation of H. pluvialis was determined to be 5 µg of the linearized vector used to transform cells in the log growth phase, and then the transformed protoplasts allowed to recover under low-intensity illumination for 6 h. This study represents and describes the successful development of an H. pluvialis transformation protocol using protoplasts, which will enable convenient genetic manipulation of this important algal species.

Spatial relationship among the density of Culex tritaeniorhynchus, Anopheles sinensis, human dwellings and pigsty in Guangxi, China: modelling study - Mei-De Liu; Chun-Xiao Li; Xiang-Yang Feng; Yan-De Dong; Mi-You Yi; Tong-Yan Zhao (International Journal of Tropical Insect Science, 2022)

Effect of PM2.5 exposure on gestational hypertension, fetal size in preeclampsia-like rats - Jie Gao; Mei Luo; Shuo Zhao; Hailing Wang; Xuan Li; Pili Xu; Wei Ma; Chongdong Liu (Environmental Science and Pollution Research, 2022)

Numerical evaluation of face masks for prevention of COVID-19 airborne transmission - Jiaxing Liu; Ming Hao; Shulei Chen; Yang Yang; Jian Li; Qi Mei; Xin Bian; Kun Liu (Environmental Science and Pollution Research, 2022)
The COVID-19 pandemic has forced governments around the globe to apply various preventive measures for public health. One of the most effective measures is wearing face masks, which plays a vital role in blocking the transmission of droplets and aerosols. To understand the protective mechanism of face masks, especially in indoor environments, we apply a computational fluid dynamics technique to predict the lifetime of cough droplets. Therefore, we can assess the exposure risk in a ventilated room where an infected individual wears a face mask or not. We focus on the dynamic evaporation and diffusion of droplets in a human-cough process, which is a major cause for the spread of the virus. We find that wearing a face mask can effectively reduce the total mass and Sauter mean diameter of the residual droplets after a single cough. The mass concentration of virus-carrying droplets in the ventilated room decreases by 201, 43,786, and 307,060 times, corresponding to wearing cotton face masks, surgical face masks, and N95 face masks, respectively. However, the maximum travel distance of 80% droplets is insensitive to wearing a face mask or not. Therefore, the residual droplets are widely distributed due to the influence of indoor airflow. Furthermore, we study aerosol exposure risks in different areas of the room and find that high concentrations of aerosols occur in the streamline through an infected individual, especially next to the individual within 1.5 m. This strongly suggests a social distance despite the fact that the majority of droplets are filtered by face masks. This study explains the impact of face masks and airflow on indoor exposure risks and further inspires potential measures for public health, for example, no individuals should sit near the air supply opening.

Organophosphate esters in children and adolescents in Liuzhou city, China: concentrations, exposure assessment, and predictors - Meng Yu; Xiang Li; Bingqing Liu; Yaping Li; Ling Liu; Limei Wang; Lulu Song; Youjie Wang; Liqin Hu; Surong Mei (Environmental Science and Pollution Research, 2022)

The Role of Long Non-coding RNA, Nuclear Enriched Abundant Transcript 1 (NEAT1) in Cancer and Other Pathologies - Miao Zhang; Jianmin Guo; Lifei Liu; Mei Huang; Yuexuan Li; Samuel Bennett; JiaKe Xu; Jun Zou (Biochemical Genetics, 2022)

Ambra1 regulates apoptosis and chemosensitivity in breast cancer cells through the Akt-FoxO1-Bim pathway - Wei-liang Sun; Ling-yan He; Li Liang; Si-yu Liu; Jie Luo; Mei-ling Lv; Zheng-wen Cai (Apoptosis, 2022)

Prenylated coumarins from the fruits of Artocarpus heterophyllus with their potential anti-inflammatory and anti-HIV activities - Lei Tao; Ya-Ting Zhuo; Ze-Hua Qiao; Juan Li; Hao-Xuan Tang; Qiao-Mei Yu; Yun-Yao Liu; Yan-Ping Liu (Natural Product Research, 2022)

Terrestrial carbon sinks in China and around the world and their contribution to carbon neutrality - Yuanhe Yang; Yue Shi; Wenjuan Sun; Jinfeng Chang; Jianxiao Zhu; Leiyi Chen; Xin Wang; Yanpei Guo; Hongtu Zhang; Lingfei Yu; Shuqing Zhao; Kang Xu; et al. (Science China Life Sciences, 2022)

Differential Effects of Sevoflurane Exposure on Long-Term Fear Memory in Neonatal and Adult Rats - Changsheng Li; Sufang Liu; Yixin Mei; Qingyong Wang; Xihua Lu; Hongle Li; Feng Tao (Molecular Neurobiology, 2022)

Fine mapping of qDB.A03, a QTL for rapeseed branching, and identification of the candidate gene - Bao Li; Tonghua Wang; Yiming Guo; Xinhong Liu; Lichao Deng; Liang Qu; Mei Li (Molecular Genetics and Genomics, 2022)

Spatial–temporal patterns of summer urban islands and their economic implications in Beijing - Lu Lin; Lina Meng; Yingdan Mei; Wenting Zhang; Hui Liu; Weiling Xiang (Environmental Science and Pollution Research, 2022)

Investigating deformation patterns of a mining-induced landslide using multisource remote sensing: The songmugou landslide in Shanxi Province, China - Ziyang Liu; Gang Mei; Yingjie Sun (Bulletin of Engineering Geology and the Environment, 2022)

Correction to: Effectiveness of Newmark‑based sampling strategy for coseismic landslide susceptibility mapping using deep learning, support vector machine, and logistic regression - Chuanjie Xi; Mei Han; Xiewen Hu; Bo Liu; Kun He; Gang Luo; Xichao Cao (Bulletin of Engineering Geology and the Environment, 2022)

Effectiveness of Newmark-based sampling strategy for coseismic landslide susceptibility mapping using deep learning, support vector machine, and logistic regression - Chuanjie Xi; Mei Han; Xiewen Hu; Bo Liu; Kun He; Gang Luo; Xichao Cao (Bulletin of Engineering Geology and the Environment, 2022)

Diel variation in anti-predation behavior of a ground squirrel and relationships between vigilance and escape - Ling-Ying Shuai; Mei-Ting Liu; A.-Ping Zhu; Yuan-Yuan Cao; Fu-Shun Zhang (Behavioral Ecology and Sociobiology, 2022)

Neobacillus rhizophilus sp. nov. and Neobacillus citreus sp. nov., isolated from the citrus rhizosphere soil - Guo-Hong Liu; Manik Prabhu Narsing Rao; Qian-Qian Chen; Huai Shi; Jian-Mei Che; Bo Liu; Wen-Jun Li (Archives of Microbiology, 2022)

Quinolizidine alkaloids from the roots of Sophora flavescens - Jian-Chun Li; Zhi-Jun Zhang; Dan Liu; Ming-Yan Jiang; Rong-Tao Li; Hong-Mei Li (Natural Product Research, 2022)

Flavonoid components and gene expression analysis reveal flower pigmentation difference between Magnolia biondii and its variety M. biondii var. purpurascens - Ning-hang Wang; Meng-yi Dai; Gang Zheng; Peng-jie Chang; Ling-juan Xuan; Zhi-gao Liu; Ya-ling Wang; Shao-yu Cheng; Zhuo-wei Wang; Hai-long Wang; Cui-hua Gu; Chao Zhang; et al. (Trees, 2022)

Enhanced genome editing to ameliorate a genetic metabolic liver disease through co-delivery of adeno-associated virus receptor - Shuming Yin; Lie Ma; Tingting Shao; Mei Zhang; Yuting Guan; Liren Wang; Yaqiang Hu; Xi Chen; Honghui Han; Nan Shen; Wenjuan Qiu; Hongquan Geng; et al. (Science China Life Sciences, 2022)

Complete chloroplast genome of Campsis grandiflora (Thunb.) schum and systematic and comparative analysis within the family Bignoniaceae - Haimei Chen; Zhuoer Chen; Qing Du; Mei Jiang; Bin Wang; Chang Liu (Molecular Biology Reports, 2022)

The complete chloroplast genome sequence of Clerodendranthus spicatus, a medicinal plant for preventing and treating kidney diseases from Lamiaceae family - Qing Du; Mei Jiang; Sihui Sun; Liqiang Wang; Shengyu Liu; Chuanbei Jiang; Haidong Gao; Haimei Chen; Yong Li; Bin Wang; Chang Liu (Molecular Biology Reports, 2022)

G-protein coupled receptor 34 regulates the proliferation and growth of LS174T cells through differential expression of PI3K subunits and PTEN - Bo Zuo; Na Wu; Shen Yang; Zhaohui Zhong; Mei Li; Xin Yu; Yulan Liu; Weidong Yu (Molecular Biology Reports, 2022)
Purpose G-protein coupled receptor (GPR 34) has been found to play important roles in some cancers and regulates the proliferation, apoptosis, and migration of these cancer cells. However, the mechanisms underlying how GPR34 functions to regulate growth and proliferation of colorectal cancer cells remains to be clarified. Methods We employed stable GPR34 knockdown LS174T cell models, GPR34 Mab blocking, a CCK-8 kit, and a colony formation assay to characterize the effect of GPR34 on the proliferation of LS174T in vitro and xenograft tumor growth in vivo. The mRNA level of GPR34 was detected by RT-PCR in tumor tissues and adjacent normal tissues from 34 CRC patients. Results Based on RT-PCR results, GPR34 exhibited high level in tumor samples compared with adjacent normal samples. Increased expression of GPR34 is more associated with poor prognosis of CRC as shown in The Cancer Genome Atlas (TCGA) dataset by Kaplan–Meier survival analysis. Furthermore, we showed that GPR34 knockdown inhibited the proliferation of LS174T colon cancer cells and related xenograft tumor growth. Searching for the distinct molecular mechanism, we identified several contributors to proliferation of LS174T colon cancer cells: PI3K subunits/PTEN, PDK1/AKT, and Src/Raf/Ras/ERK. GPR34 knockdown inhibited the proliferation of LS174T cells by upregulating expression of PTEN, and downregulating expression of PI3K subunits p110-beta. Conclusion Our findings provide direct evidence that GPR34 regulates the proliferation of LS174T cells and the growth of LS174T tumor xenografts by regulating different pathways. High expression of GPR34 mRNA could then be used to predict poor prognosis of CRC.

Differential linkages between soil respiration components and microbial community structures under long-term forest conversion - Rudong Zhao; Mei He; Feng Liu (Journal of Soils and Sediments, 2022)

Effects of Meranzin Hydrate On the LncRNA–miRNA–mRNA Regulatory Network in the Hippocampus of a Rat Model of Depression - Kechao Nie; Lin Liu; Luqi Peng; Mei Zhang; Chunhu Zhang; Bo Xiao; Zian Xia; Wei Huang (Journal of Molecular Neuroscience, 2022)

Subcellular localization and identification of acyl-CoA: lysophosphatidylethanolamine acyltransferase (LPEAT) in the arachidonic acid-rich green microalga, Myrmecia incisa Reisigl - Yi Liu; Hong Bao; Mei-Li Zhu; Cheng-Xi Hu; Zhi-Gang Zhou (Journal of Applied Phycology, 2022)

Cloning and expression of kiss genes and regulation of feeding in Siberian sturgeon (Acipenser baerii) - Shaoqi Xu; Mei Wang; Ya Li; Ni Tang; Xin Zhang; Hu Chen; Shupeng Zhang; Yanling Liu; Jun Wang; Defang Chen; Zhiqiong Li (Fish Physiology and Biochemistry, 2022)

Updated network meta-analysis assessing the relative efficacy of 13 GLP-1 RA and SGLT2 inhibitor interventions on cardiorenal and mortality outcomes in type 2 diabetes - Mei Qiu; Wei Wei; Xu-Bin Wei; Shu-Yan Liu (European Journal of Clinical Pharmacology, 2022)

Alternaria species causing leaf spot on hemp (Cannabis sativa) in Northern China - Hong Cheng; Lin Zhao; Xin Wei; Xi Liu; Guo-Yang Gao; Jian-Xin Deng; Mei-Jia Li (European Journal of Plant Pathology, 2022)

Assessment of the effectiveness of a field-scale combined ecological treatment system at removing water pollutants, after optimization using a system dynamic model: a case study of rural inland ponds in China - Mei Liu; Julin Yuan; Meng Ni; Qingping Lian (Environmental Science and Pollution Research, 2022)

Soil microbial stoichiometry and community structure responses to long-term natural forest conversion to plantations in a subtropical region - Rudong Zhao; Mei He; Canlan Jiang; Feng Liu (Environmental Science and Pollution Research, 2022)

Correction to: Lederbergia citri sp. nov., and Lederbergia citrisecundus sp. nov., isolated from citrus rhizosphere - Guo‑Hong Liu; Manik Prabhu Narsing Rao; Qian‑Qian Chen; Jian‑Mei Che; Huai Shi; Bo Liu; Wen‑Jun Li (Current Microbiology, 2022)

Investigation on grouting diffusion in inclined fracture with flowing water conditions - Jia-fan Zhang; Xun-xun Chen; Yang Liu; Hui-mei Zhang; Chun-lin Wang; Gang Fang (Arabian Journal of Geosciences, 2022)

Isolated intracranial xanthogranuloma involving the Meckel’s cave in an adult: a case report - Yang Wen; Yu-mei Li; Biao Zhu; Xin Liu; Ming Zhao (Acta Neurologica Belgica, 2022)

Effects of the East Asian subtropical westerly jet on winter persistent heavy pollution in the Beijing–Tianjin–Hebei region - Mei Mei; Yihui Ding; Zunya Wang; Yanju Liu; Yingxian Zhang (International Journal of Climatology, 2022)
Based on the daily average concentration of PM 2.5 , 15 typical persistent heavy pollution episodes (PHPEs) in the Beijing–Tianjin–Hebei (BTH) region during the winters of 2013–2019 are identified. And then the impact of the intra‐seasonal variations of the 200‐hPa subtropical westerly jet (SWJ) on the PHPEs is investigated. The results show that the SWJ affects the lifecycle of the PHPEs in the BTH region mainly through the meridional shift and intensity variation. In particular, the intensity variation has a closer relationship with the vertical velocity and low‐level meridional wind to affect the PHPEs. In the developing stage of the PHPEs, the SWJ shifts northward and strengthens. The BTH region is on the left side of the entrance of the SWJ and the vertical secondary circulation intensifies the descending motion in situ. As a result, the atmospheric boundary layer is compressed to sink rapidly, a temperature inversion in the lower levels appears and the atmospheric stability is enhanced. Finally, the atmospheric environment is favourable for the rapid accumulation of pollutants and the occurrence of the PHPEs. In the peak stage, the southward withdrawal and weakening of the SWJ favour the anomalous ascending motion and low‐level southerly anomalies over the BTH region. The dominant role of the dynamic descending motion is replaced by the low‐level southerly anomalies to enhance the PHPEs, by transporting more warm‐humid air to the BTH region. In the weakening stage, the SWJ moves northward and intensifies again. The low‐level southerly anomalies weaken to contribute to the dissipation of the pollutants.

The management of bone defect using long non-coding RNA as a potential biomarker for regulating the osteogenic differentiation process - Jia-lin Liu; Yan-shi Liu; Mei-jie Zheng; Hui-yu He (Molecular Biology Reports, 2022)
Tissue engineered bone brings hope to the treatment of bone defects, and the osteogenic differentiation of stem cells is the key link. Inducing osteogenic differentiation of stem cells may be a potential approach to promote bone regeneration. In recent years, lncRNA has been studied in the field increasingly, which is believed can regulate cell cycle, proliferation, metastasis, differentiation and immunity, participating in a variety of physiology and pathology processes. At present, it has been confirmed that certain lncRNAs regulate the osteogenesis of stem cells and take part in mediating signaling pathways including Wnt/β-catenin, MAPK, TGF-β/BMP, and Notch pathways. Here, we provided an overview of lncRNA, reviewed its researches in the osteogenic differentiation of stem cells, emphasized the importance of lncRNA in bone regeneration, and focused on the roles of lncRNA in signaling pathways, in order to make adequate preparations for applying lncRNA to bone tissue Engineering, letting it regulate the osteogenic differentiation of stem cells for bone regeneration.

The branch-thorn occurrence of Lycium ruthenicum is associated with leaf DNA hypermethylation in response to soil water content - Ailin Yang; Xinyu Qi; Qin-Mei Wang; Hao Wang; Yucheng Wang; Lujia Li; Wen Liu; Yang Qiao (Molecular Biology Reports, 2022)

miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β - Hongxin Xu; Ying Cui; Xianwei Liu; Xiao Zheng; Jiaqing Liu; Xinxin Hu; Fuhua Gao; Xiaoyan Hu; Mei Li; Xiaoqing Wei; Ying Gao; Ying Zhao (Molecular Biology Reports, 2022)

Ferroptosis promotes microtubule-associated protein tau aggregation via GSK-3β activation and proteasome inhibition - Shaohui Wang; Yao Jiang; Yabo Liu; Qianhui Liu; Hongwei Sun; Mengjie Mei; Xiaomei Liao (Molecular Neurobiology, 2022)

New insights into the occurrence of the catastrophic Zhaiban slope debris flow that occurred in a dry valley in the Hengduan Mountains in southwest China - Shufeng Tian; Ningsheng Chen; Mahfuzur Rahman; Guisheng Hu; Taixin Peng; Yong Zhang; Mei Liu (Landslides, 2022)

Effects of extreme precipitation on hospitalization risk and disease burden of schizophrenia in urban and rural Lu’an, China, from 2010 to 2019 - Yudong Wu; Zhenghai Yao; Gongyan Ma; Jian Cheng; Huabin Xu; Wei Qin; Weizhuo Yi; Rubing Pan; Qiannan Wei; Chao Tang; Xiangguo Liu; Yangyang He; et al. (Environmental Science and Pollution Research, 2022)

Biological monitoring and health assessment of 21 metal(loid)s in children and adolescents in Liuzhou City, Southwest China - Yaping Li; Yu Zhang; Meng Yu; Liqin Hu; Ting Zeng; Ling Liu; Limei Wang; Liangqiong Deng; Xiang Li; Ping Liu; Dingyuan Zeng; Surong Mei (Environmental Science and Pollution Research, 2022)

Development and validation of a transcriptomic signature-based model as the predictive, preventive, and personalized medical strategy for preterm birth within 7 days in threatened preterm labor women - Yuxin Ran; Jie He; Wei Peng; Zheng Liu; Youwen Mei; Yunqian Zhou; Nanlin Yin; Hongbo Qi (EPMA Journal, 2022)

Strigolactone is involved in nitric oxide-enhanced the salt resistance in tomato seedlings - Huwei Liu; Changxia Li; Mei Yan; Zongxi Zhao; Panpan Huang; Lijuan Wei; Xuetong Wu; Chunlei Wang; Weibiao Liao (Journal of Plant Research, 2022)

A bi-scale assessing framework for aesthetic ecosystem services of villages in a world heritage site - Yin-ping Ding; Zhi-lin Liu; Yuan-mei Jiao; Qiu-e Xu; Kan-feng Zhang; Cheng-jing Liu; Fan Chen (Journal of Mountain Science, 2022)

Description of Aureibaculum luteum sp. nov. and Aureibaculum flavum sp. nov. isolated from Antarctic intertidal sediments - Xiao-yan He; Ning-hua Liu; Chao-yi Lin; Mei-ling Sun; Xiu-lan Chen; Yu-zhong Zhang; Yu-qiang Zhang; Xi-ying Zhang (Antonie van Leeuwenhoek, 2022)

Stilbenoids from the roots of Stemona tuberosa - Hong-Mei Li; Tian-Tian He; Miao Zhang; Jia-Ning Liu; Xue Zhao; Jie Liu; Lei Fang (Natural Product Research, 2022)

Oxygen Metabolism-induced Stress Response Underlies Heart–brain Interaction Governing Human Consciousness-breaking and Attention - Xiao-Juan Xue; Rui Su; Ze-Feng Li; Xiao-Ou Bu; Peng Dang; Si-Fang Yu; Zhi-Xin Wang; Dong-Mei Chen; Tong-Ao Zeng; Ming Liu; Hai-Lin Ma; De-Long Zhang (Neuroscience Bulletin, 2022)

MiR-196a promotes the proliferation and migration of esophageal cancer via the UHRF2/TET2 axis - Chang-mei Hu; Jie Peng; Liang Lv; Xue-hong Wang; Ji-rong Huo; De-liang Liu (Molecular and Cellular Biochemistry, 2022)

MiR-582-3p participates in the regulation of biological behaviors of A549 cells by ambient PM2.5 exposure - Mei Yang; Liangliang Ju; Changlian Li; Han Cheng; Na Li; Qi Zhang; Shu Sun; Liu Ding; Xinmiao Sui; Chao Zhang; Mingwei Yang; Jiyu Cao; et al. (Environmental Science and Pollution Research, 2022)

Lederbergia citri sp. nov., and Lederbergia citrisecundus sp. nov., isolated from citrus rhizosphere - Guo-Hong Liu; Manik Prabhu Narsing Rao; Qian-Qian Chen; Jian-Mei Che; Huai Shi; Bo Liu; Wen-Jun Li (Current Microbiology, 2022)

Moisture management in biochar-amended green roofs planted with Ophiopogon japonicus under different irrigation schemes: an integrated experimental and modeling approach - Jiaqin Liu; Ankit Garg; Hao Wang; Shan Huang; Guoxiong Mei (Acta Geophysica, 2022)

Special roles for efflux systems in iron homeostasis of non‐siderophore‐producing cyanobacteria - Ling‐Mei Liu; Ding‐Lan Li; Bin Deng; Xin‐Wei Wang; Hai‐Bo Jiang (Environmental Microbiology, 2022)
Summary In oligotrophic oceans, low bioavailability of Fe is a key factor limiting primary productivity. However, excessive Fe in cells leads to the Fenton reaction, which is toxic to cells. Cyanobacteria must strictly maintain intracellular Fe homeostasis. Here, we knocked out a series of genes encoding efflux systems in Synechocystis sp. PCC 6803, and found eight genes that are required for high Fe detoxification. Unexpectedly, the HlyBD‐TolC efflux system plays an important role in the adaptation of Synechocystis under Fe‐deficient conditions. Mutants of HlyD and TolC grew worse than the wild‐type strain under low‐Fe conditions and showed significantly lower intracellular Fe contents than the wild‐type strain. We excluded the possibility that the low Fe sensitivity of the HlyBD‐TolC mutants was caused by a loss of the S‐layer, the main extracellular protein secreted via this efflux system. Inactivation of the HlyD protein influenced type IV pili formation and direct inactivation of type IV pili related genes affected the adaptation to low‐Fe conditions. HlyBD‐TolC system is likely involved in the formation of type IV pili and indirectly influenced Fe acquisition. Our findings suggest that efflux system in non‐siderophore‐producing cyanobacteria can facilitate Fe uptake and help cells adapt to Fe‐deficient conditions via novel pathways.

Two new iridoid glycosides from the fruit of Gardenia jasminoides - Hai-Bo Li; Jin-Feng Ma; Yu-Dan Mei; Ling-Xian Liu; Ze-yu Cao; Dan-Feng Shi; Xin-Sheng Yao; Yang Yu (Natural Product Research, 2022)

Precise editing of methylated cytosine in Arabidopsis thaliana using a human APOBEC3Bctd-Cas9 fusion - Zhi-Hong Liu; Shanjie Tang; Wentao Hu; Ruo Lv; Hailiang Mei; Rongxin Yang; Xianwei Song; Xiaofeng Cao; Dong Wang (Science China Life Sciences, 2022)

GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells - Qianqian Pang; Chunyi Liu; Yulong Qiao; Jian Zhao; Sin Man Lam; Mei Mei; Guanghou Shui; Shilai Bao; Qiuling Li (Science China Life Sciences, 2022)

Spatial matching and flow in supply and demand of water provision services: A case study in Xiangjiang River Basin - Chu-xiong Deng; Da-mei Zhu; Yao-jun Liu; Zhong-wu Li (Journal of Mountain Science, 2022)

Effect of feed restriction on the intestinal microbial community structure of growing ducks - Jun-peng Li; Qi-fan Wu; Sheng-chao Ma; Jian-mei Wang; Bin Wei; Yang Xi; Chun-chun Han; Liang Li; Hua He; He-he Liu (Archives of Microbiology, 2022)

Azospirillum tabaci sp. nov., a bacterium isolated from rhizosphere soil of Nicotiana tabacum L - Yan-Qing Duan; Xing-Kui Zhou; Neeli Habib; Shi-Qiang Gao; Li-Min Dong; Xiao-Fei Liu; Yang-Mei Shi; Wen-Jun Li; Gang Du (Archives of Microbiology, 2022)

How does the onset time of El Niño events affect tropical cyclone genesis and intensity over the western North Pacific ? - Mei Liang; Jianjun Xu; Johnny C. L. Chan; Chunlei Liu; Hua Xu (International Journal of Climatology, 2022)
Previous studies have shown that the equatorial Pacific Ocean warming can be separated into spring (April~June; SP) and summer (July~October; SU) modes based on the onset time of El Niño events. Different onset times are caused by different atmospheric and oceanic conditions, which, in turn, should influence tropical cyclone (TC) activity. While the location of TC formation in the western North Pacific (WNP) shifts significantly eastward and equatorward in the SP type relative to climatology (1951–2017), only an eastward shift occurs in the SU type. Only intense TCs (category 1 + 2 + 3 and 4 + 5) have an obvious eastward and equatorward shift in the SP type, with no such shift in any TC category in the SU type. The number of category 4 + 5 TCs in the SP type increases significantly, but fewer category 1 + 2 + 3 TCs in the SU type. In the SP type, TCs are generally stronger, with more in category 4 + 5, and longer life spans occurring across all categories. However, no obvious change in TC intensity can be identified except for category 1 + 2 + 3 in the SU type. The eastward and equatorward shift of the mean genesis position in the developing phases of SP can be attributed to a southeastward shift of favourable atmospheric and oceanic conditions, which include weaker zonal vertical wind shear, stronger relative vorticity, higher mid‐level relative humidity, and enhanced upper‐ocean temperature (5–100 m). All these conditions are mainly related to the onset time of the westerly anomalies near the central equatorial Pacific. These results suggest that the onset time of El Niño events could serve as a good forecasting indicator for TC genesis position and intensity over the WNP.

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

Benzofuran derivatives with nerve growth factor-potentiating activity from Phellinus ribis - Mei-Yue Dong; Yan Zhang; Hai-Qiang Jiang; Wen-Jing Ren; Ling-Chuan Xu; Yong-Qing Zhang; Yu-Hong Liu (Natural Product Research, 2021)

Two new 19-hydroxy bufadienolides with cytotoxic activity from the skins of Bufo melanosticus - Lingjie Meng; Sanhua Li; Qinghong Kong; Mei Wang; Xiaoke Zhang; Xinting Zhu; Wei Yu; Nian Jiang; Zeli Chun; Nian Li; Yun Liu (Natural Product Research, 2021)

Effective Thermal Conductivity Estimation of Fractured Rock Masses - Zheng-Wei Li; Yuan Liu; Shi-Ming Mei; Shi-Cheng Xing; Xiao-Kai Wang (Rock Mechanics and Rock Engineering, 2021)

The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus - Zhuang Liu; Shuai Huang; Man Xu; Wenxue Zhang; Tuchen Guan; Qinghua Wang; Mei Liu; Jian Yao; Yan Liu (Journal of Molecular Histology, 2021)

MiR-96-5p is an oncogene in lung adenocarcinoma and facilitates tumor progression through ARHGAP6 downregulation - Zhifang Liu; Yong Cui; Shuwei Wang; Changhao Wu; Fuyang Mei; Erlei Han; Zhibin Hu; Bing Zhou (Journal of Applied Genetics, 2021)

Volatilization process of toluene from contaminated soil under consideration of co-existence of pore water - Liangliang Lu; Zhibin Liu; Shangan Li; Mei Bai; Zhanhuang Fan (Environmental Science and Pollution Research, 2021)

Long-term changes of water acidity in an intact forested watershed in south China - Xiao-dong Liu; Ying-jie Feng; Qi-feng Mo; Guo-wei Chu; Yue-lin Li; Qian-mei Zhang; Wei-qiang Zhang; Xian-hua Gan; Qing Zhou (Journal of Mountain Science, 2021)

Influence of biochar amendment on stormwater management in green roofs: experiment with numerical investigation - Lin Gan; Ankit Garg; Hao Wang; Guoxiong Mei; Jiaqin Liu (Acta Geophysica, 2021)

Characterization and identification of SFDC ‐1, a novel AmpC ‐type β‐lactamase in Serratia fonticola - Xu Dong; Peiyao Zhang; Kexin Zhou; Jialei Liang; Qiaoling Li; Xueya Zhang; Danying Zhou; Wei Lu; Zhewei Sun; Hongmao Liu; Junwan Lu; Xi Lin; et al. (Environmental Microbiology, 2021)
Summary The clinical and environmental infections caused by AmpC β‐lactamases have been increasingly reported recently. In this study, we characterize the novel chromosome‐encoded AmpC β‐lactamase SFDC‐1 identified in Serratia fonticola strain R28, which was isolated from a rabbit raised on a farm in southern China. SFDC‐1 shared the highest amino acid identity of 79.6% with the functionally characterized AmpC β‐lactamase gene bla YRC‐1 , although it had highly homologous functionally uncharacterized relatives in the same species from different sources, including some of the clinical significance. The cloned bla SFDC‐1 exhibited resistance to a broad spectrum of β‐lactam antibiotics, including most cephalosporins with the highest resistance to ampicillin, cefazolin and ceftazidime, with increased MIC levels ≥128‐fold compared with the control strains. The purified SFDC‐1 showed catalytic activities against β‐lactams with the highest catalytic activity to cefazolin. The genetic context of bla SFDC‐1 and its relatives was conserved in the chromosome, and no mobile genetic elements were found surrounding them.

Three new diterpenoids from Euphorbia peplus - Yan-Ni Chen; Qing-Yun Lu; Dong-Mei Li; Ying-Yao Li; Xue-Xue Pu; Bo-Ting Li; Xiao-Han Tang; Hong-Yu Tang; Shuai Liu; Lei Yang; Yu Zhang; Ying-Tong Di; et al. (Natural Product Research, 2021)

New cyclopentenoneacrylic acid derivatives from a marine-derived fungus Trichoderma atroviride H548 - Xi-Xiang Tang; Shun-Zhi Liu; Yu-Ying Sun; Feng-Ming He; Guang-Xin Xu; Mei-Juan Fang; Wu Zhen; Ying-Kun Qiu (Natural Product Research, 2021)

Three new cycloart-7-ene triterpenoid glycosides from Cimicifuga dahurica and their anti-inflammatory effects - Qian-Qian Pang; Yu-Dan Mei; Yuan-Chu Zhang; Ling-Xian Liu; Dan-Feng Shi; Da-Bo Pan; Xin-Sheng Yao; Hai-Bo Li; Yang Yu (Natural Product Research, 2021)

1,4-Dioxane Degradation Performance of Tetrahydrofuran-Grown Arthrobacter sp. WN18 - Peng Wang; Tingchen Cui; Jialu Li; Na Liu; Mei Hong (Water, Air, & Soil Pollution, 2021)

An Ensemble Hybrid Forecasting Model for Annual Runoff Based on Sample Entropy, Secondary Decomposition, and Long Short-Term Memory Neural Network - Wen-chuan Wang; Yu-jin Du; Kwok-wing Chau; Dong-mei Xu; Chang-jun Liu; Qiang Ma (Water Resources Management, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Genomic characterization of a rare Carica papaya X chromosome mutant reveals a candidate monodehydroascorbate reductase 4 gene involved in all-hermaphrodite phenomenon - Jen-Ren Chen; Hiroki Ueno; Hideo Matsumura; Naoya Urasaki; Chen-Yu Lee; Fure-Chyi Chen; Shih-Wen Chin; Chun-Chi Liu; Chan-Tai Chiu; Kazuhiko Tarora; Jing-Yi Li; Chieh Ying Lee; et al. (Molecular Genetics and Genomics, 2021)

Cardiovascular safety of long-term anti-obesity drugs in subjects with overweight or obesity: a systematic review and meta-analysis - Lin Zhang; Zhi Liu; Shenling Liao; He He; Mei Zhang (European Journal of Clinical Pharmacology, 2021)

Associations between air pollution exposure and birth defects: a time series analysis - Shu Sun; Qi Zhang; Xinmiao Sui; Liu Ding; Jie Liu; Mei Yang; Qihong Zhao; Chao Zhang; Jiahu Hao; Xiujun Zhang; Shilei Lin; Rui Ding; et al. (Environmental Geochemistry and Health, 2021)

Differential metabolism-associated gene expression of duck pancreatic cells in response to two strains of duck hepatitis A virus type 1 - Zhen Chen; Shao-hua Shi; Yu Huang; Cui-qin Huang; Rong-chang Liu; Long-fei Cheng; Guang-hua Fu; Hong-mei Chen; Chun-he Wan; Qiu-ling Fu (Archives of Virology, 2021)
Several outbreaks of duck hepatitis A virus type 1 (DHAV-1), which were characterized by yellow coloration and hemorrhage in pancreatic tissues, have occurred in China. The causative agent is called pancreatitis-associated DHAV-1. The mechanisms involved in pancreatitis-associated DHAV-1 infection are still unclear. Transcriptome analysis of duck pancreas infected with classical-type DHAV-1 and pancreatitis-associated DHAV-1 was carried out. Deep sequencing with Illumina-Solexa resulted in a total of 53.9 Gb of clean data from the cDNA library of the pancreas, and a total of 29,597 unigenes with an average length of 993.43 bp were generated by de novo sequence assembly. The expression levels of D-3-phosphoglycerate dehydrogenase, phosphoserine aminotransferase, and phosphoserine phosphatase, which are involved in glycine, serine, and threonine metabolism pathways, were significantly downregulated in ducks infected with pancreatitis-associated DHAV-1 compared with those infected with classical-type DHAV-1. These findings provide information regarding differences in expression levels of metabolism-associated genes between ducks infected with pancreatitis-associated DHAV-1 and those infected with classical-type DHAV-1, indicating that intensive metabolism disorders may contribute to the different phenotypes of DHAV-1-infection.

A new nitrogen-containing iridoid glycoside from lonicera macranthoides - Yu-Dan Mei; Hai-Bo Li; Ling-Xian Liu; Dan-feng Shi; Da-bo Pan; Xin-Sheng Yao; Yang Yu (Natural Product Research, 2021)

A new ergostane derivative from the leaves of Heynea trijuga Roxburgh - Shou-Bai Liu; Zheng Cui; Hui-Qin Chen; Hao Wang; Wen-Hua Dong; Cai-Hong Cai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice - Lin Chen; Shu-Yu Ren; Rui-Xue Li; Kun Liu; Jing-Fei Chen; Yu-Jian Yang; Yong-Bin Deng; Han-Zhi Wang; Lan Xiao; Feng Mei; Fei Wang (Neuroscience Bulletin, 2021)
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths ( NG2-CreER TM ; Tau-mGFP ), we found that myelinogenesis was highly active in most brain regions, such as the motor cortex and corpus callosum. After exposure to hypoxia (10% oxygen) 12 h per day for 4 weeks, myelinogenesis was largely inhibited in the 4-month old brain and the mice displayed motor coordination deficits revealed by the beam-walking test. To determine the relationship between the inhibited myelination and functional impairment, we induced oligodendroglia-specific deletion of the transcription factor Olig2 by tamoxifen ( NG2-CreER TM ; Tau-mGFP; Olig2 fl/fl ) in adult mice to mimic the decreased myelinogenesis caused by hypoxia. The deletion of Olig2 inhibited myelinogenesis and consequently impaired motor coordination, suggesting that myelinogenesis is required for motor function in adult mice. To understand whether enhancing myelination could protect brain functions against hypoxia, we treated hypoxic mice with the myelination-enhancing drug-clemastine, which resulted in enhanced myelogenesis and improved motor coordination. Taken together, our data indicate that chronic hypoxia inhibits myelinogenesis and causes functional deficits in the brain and that enhancing myelinogenesis protects brain functions against hypoxia-related deficits.

Activation of the Hippocampal LXRβ Improves Sleep-Deprived Cognitive Impairment by Inhibiting Neuroinflammation - Chen Qiu; Min Wang; Wen Yu; Zheng Rong; He-Sheng Zheng; Ting Sun; Shui-Bing Liu; Ming-Gao Zhao; Yu-Mei Wu (Molecular Neurobiology, 2021)

Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling - Juan-Juan Song; Mei Yang; Ying Liu; Jia-Wei Song; Xiao-Yan Liu; Ran Miao; Zhen-Zhou Zhang; Yu Liu; Yi-Fan Fan; Qian Zhang; Ying Dong; Xin-Chun Yang; et al. (Journal of Molecular Histology, 2021)

Correction to: Stocking density alters growth performance, serum biochemistry, digestive enzymes, immune response, and muscle quality of largemouth bass (Micropterus salmoides) in in-pond raceway system - Julin Yuan; Meng Ni; Mei Liu; Jianfeng Lou; Guoqiang Mi; Zhimin Gu (Fish Physiology and Biochemistry, 2021)

Exploring trophic role similarity and phylogenetic relatedness between species in food webs - Shu-mei Lai; Wei-chung Liu; Hsuan-wien Chen (Community Ecology, 2021)

Spatial and temporal variations in nitrogen retention effects in a subtropical mountainous basin in Southeast China - Mei-bing Liu; Xing-wei Chen; Ying Chen; Lu Gao; Hai-jun Deng (Journal of Mountain Science, 2021)

Analytical solution of grouting fracturing height for the post-grouted bored piles using the Herschel–Bulkley model with time-varying viscosity - Gan Nan; Hai-ming Liu; Yong-mei Peng; Rui Liang; Hong-tao Xie; Jing Cao (Arabian Journal of Geosciences, 2021)

Synthesis, characterization and in vitro anti-proliferative effects of pentacyclic triterpenoids - Qian Wang; Mei Jin; Yandan Liu; Lei Sun; Bo Lu; Longxuan Zhao; Gao Li (Medicinal Chemistry Research, 2021)

Short-Term Daily Prediction of Sea Ice Concentration Based on Deep Learning of Gradient Loss Function - Quanhong Liu; Ren Zhang; Yangjun Wang; Hengqian Yan; Mei Hong (Frontiers in Marine Science, 2021)
The navigability potential of the Northeast Passage has gradually emerged with the melting of Arctic sea ice. For the purpose of navigation safety in the Arctic area, a reliable daily sea ice concentration ( SIC ) prediction result is required. As the mature application of deep learning technique in short-term prediction of other fields (atmosphere, ocean, and hurricane, etc.), a new model was proposed for daily SIC prediction by selecting multiple factors, adopting gradient loss function (Grad-loss) and incorporating an improved predictive recurrent neural network (PredRNN++). Three control experiments are designed to test the impact of these three improvements for model performance with multiple indicators. Results show that the proposed model has best prediction skill in our experiments by taking physical process and local SIC variation into consideration, which can continuously predict daily SIC for up to 9 days.

Effects of Melanin Extraction on Biosorption Behavior of Chestnut Shells Towards Methylene Blue - Zhang-Fen Liu; Zhang-Jun Liu; Li-Mei Qie; Zeng-Yu Yao (Water Conservation Science and Engineering, 2021)

Characterization of Annexin gene family and functional analysis of RsANN1a involved in heat tolerance in radish (Raphanus sativus L.) - Feng Shen; Jiali Ying; Liang Xu; Xiaochuan Sun; Jizhong Wang; Yan Wang; Yi Mei; Yuelin Zhu; Liwang Liu (Physiology and Molecular Biology of Plants, 2021)

Multifunctional graphene-based nanocomposites for simultaneous enhanced photocatalytic degradation and photothermal antibacterial activity by visible light - Ya-kun Lv; Lin Mei; Liu-xue Zhang; De-hong Yang; Zi-yu Yin (Environmental Science and Pollution Research, 2021)

Efficient biotransformation of sulfide in anaerobic sequencing batch reactor by composite microbial agent: performance optimization and microbial community analysis - Huan Liu; Luyao Dai; Jiachao Yao; Yu Mei; Dzmitry Hrynsphan; Savitskaya Tatsiana; Jun Chen (Environmental Science and Pollution Research, 2021)

Risk assessment and ecotoxicological effects of leachates extracted from industrial district soils of Nanjing, China - Yu Feng; Feng Liu; Mei Li; Yibin Cui; Xiaofeng Jiang; Xiezhi Yu (Ecotoxicology, 2021)

Risk assessment and ecotoxicological diagnosis of soil from a chemical industry park in Nanjing, China - Tong Zhang; Feng Liu; Xiezhi Yu; Xiaofeng Jiang; Yibin Cui; Mei Li (Ecotoxicology, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Regional seismic damage analysis considering soil–structure cluster interaction using lumped parameter models: a case study of Sichuan University Wangjiang Campus buildings - Bowen Zhang; Feng Xiong; Yang Lu; Qi Ge; Yang Liu; Zhu Mei; Mingming Ran (Bulletin of Earthquake Engineering, 2021)

Do rapid photosynthetic responses protect maize leaves against photoinhibition under fluctuating light? - Mei-Yu Qiao; Ya-Jun Zhang; Li-An Liu; Lei Shi; Qing-Hu Ma; Wah Soon Chow; Chuang-Dao Jiang (Photosynthesis Research, 2021)

Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination - Kun Liu; Bin Yu; Jing-Fei Chen; Rui-Xue Li; Lin Chen; Shu-Yu Ren; Fei Wang; Feng Mei; Lan Xiao (Neuroscience Bulletin, 2021)
Increasing evidence has shown that astrocytes are implicated in regulating oligodendrocyte myelination, but the underlying mechanisms remain largely unknown. To understand whether microRNAs in astrocytes function in regulating oligodendroglial differentiation and myelination in the developing and adult CNS, we generated inducible astrocyte-specific Dicer conditional knockout mice (hGFAP-CreERT; Dicer fl/fl). By using a reporter mouse line (mT/mG), we confirmed that hGFAP-CreERT drives an efficient and astrocyte-specific recombination in the developing CNS, upon tamoxifen treatment from postnatal day 3 (P3) to P7. The Dicer deletion in astrocytes resulted in inhibited oligodendroglial differentiation and myelination in the developing CNS of Dicer cKO mice at P10 and P14, and did not alter the densities of neurons or axons, indicating that Dicer in astrocytes is required for oligodendrocyte myelination. Consequently, the Dicer deletion in astrocytes at P3 resulted in impaired spatial memory and motor coordination at the age of 9 weeks. To understand whether Dicer in astrocytes is also required for remyelination, we induced Dicer deletion in 3-month-old mice and then injected lysolecithin into the corpus callosum to induce demyelination. The Dicer deletion in astrocytes blocked remyelination in the corpus callosum 14 days after induced demyelination. Together, our results indicate that Dicer in astrocytes is required for oligodendroglia myelination in both the developing and adult CNS.

Comparative Genomics and Molecular Analysis of Epidermophyton floccosum - Jia Liu; Liyu Ge; Huan Mei; Hailin Zheng; Jingwen Peng; Guanzhao Liang; Weida Liu (Mycopathologia, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Stocking density alters growth performance, serum biochemistry, digestive enzymes, immune response, and muscle quality of largemouth bass (Micropterus salmoides) in in-pond raceway system - Meng Ni; Mei Liu; Jianfeng Lou; Guoqiang Mi; Julin Yuan; Zhimin Gu (Fish Physiology and Biochemistry, 2021)

Incidence risk of PD-1/PD-L1–related pneumonia and diarrhea in non-small cell lung cancer (NSCLC) patients: a systematic review and meta-analysis of randomized controlled trials - Zhi-Qiang Tong; Dong-Yuan Wu; Duo Liu; Mei Dong (European Journal of Clinical Pharmacology, 2021)

Revealing the impact of water conservancy projects and urbanization on hydrological cycle based on the distribution of hydrogen and oxygen isotopes in water - Chengcheng Xia; Guodong Liu; Jing Zhou; Yuchuan Meng; Ke Chen; Pengfei Gu; Mengxi Yang; Xiaohua Huang; Jie Mei (Environmental Science and Pollution Research, 2021)

Efficient Degradation of 2,4-Dichlorophenol on Activation of Peroxymonosulfate Mediated by MnO2 - Jingliang Liu; Fengxia An; Mei Li; Lu Yang; Jinzhong Wan; Shengtian Zhang (Bulletin of Environmental Contamination and Toxicology, 2021)

Overexpression of ZmNF-YC13 Confers ER Stress Tolerance in Maize - Xiupeng Mei; Chaoxian Liu; Jin Nan; Zikun Zhao; Yang Bai; Erfei Dong; Yilin Cai (Journal of Plant Biology, 2021)

Coupling effects of hydrological characteristics and nutrient load in sediments on the trophic state of reservoirs - Fan Xinyi; Yue Yihong; Mei Lin; Li Xiaoying; Hu Zhehui; Luo Jiajie; Liu Liu; Wang Fushun (Acta Geochimica, 2021)

A new ent -kaurane diterpene from Isodon henryi - Xue Jiang; Ling-Xia Zhang; Qing-Mei Feng; Hong Wu; Ya-Lin Liu; De-Qin Wang; Li-Ping Dai; Zhi-Min Wang (Natural Product Research, 2021)

Intermittent Hypoxia Activates N-Methyl-D-Aspartate Receptors to Induce Anxiety Behaviors in a Mouse Model of Sleep-Associated Apnea - Yun Fan; Mei-Chuan Chou; Yen-Chin Liu; Ching-Kuan Liu; Chu-Huang Chen; Shiou-Lan Chen (Molecular Neurobiology, 2021)

Development of markers for identification and maker-assisted breeding of Xa7 gene in rice (Oryza sativa L.) - Pengcheng Liu; Le Mei; Lumei He; Yiling Xu; Yiting Zhang; Dali Zeng; Xiaoming Zhang; Qian Qian; Xifeng Chen; Bojun Ma (Euphytica, 2021)

Electricity end-use and construction activity are key leverage points for co-controlling greenhouse gases and local pollution in China - Li-Jing Liu; Qiao-Mei Liang; Felix Creutzig; Nan Cheng; Lan-Cui Liu (Climatic Change, 2021)

Complete genome sequence of a novel citrus virus with characteristics of members of the family Tymoviridae - Liu Yang; Song Zhang; Shiqiang Mei; Qiyan Liu; Yan Zhou; Ruhui Li; Mengji Cao (Archives of Virology, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

A comparative study of the recent most potent small-molecule PD-L1 inhibitors: what can we learn? - Mei Liu; Yu Zhang; Yu Guo; Jian Gao; Wenhai Huang; Xiaowu Dong (Medicinal Chemistry Research, 2021)

Correction to: Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

LAI scale effect research based on compact airborne spectrographic imager data in the Heihe Oasis - Xiao-ai Dai; Chao Liu; Nai-wen Li; Mei-lian Wang; Yu-wei Yang; Xing-ping Yang; Shi-qi Zhang; Xu-wei He; Zheng-li Yang; Heng Lu; Jing-zhong Li; Ze-kun Wang (Journal of Mountain Science, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Overcoming diverse homologous recombinations and single chimeric guide RNA competitive inhibition enhances Cas9‐based cyclical multiple genes coediting in filamentous fungi - Youzhi Miao; Yanwei Xia; Yanqiong Kong; Han Zhu; Huiling Mei; Pan Li; Haichao Feng; Weibing Xun; Zhihui Xu; Nan Zhang; Dongyang Liu; Qirong Shen; et al. (Environmental Microbiology, 2021)
Summary Deciphering the complex cellular behaviours and advancing the biotechnology applications of filamentous fungi increase the requirement for genetically manipulating a large number of target genes. The current strategies cannot cyclically coedit multiple genes simultaneously. In this study, we firstly revealed the existence of diverse homologous recombination (HR) types in marker‐free editing of filamentous fungi, and then, demonstrated that sgRNA efficiency‐mediated competitive inhibition resulted in the low integration of multiple genetic sites during coediting, which are the two major obstacles to limit the efficiency of cyclically coediting of multiple genes. To overcome these obstacles, we developed a biased cutting strategy by Cas9 to greatly enhance the desired HR type and applied a new selection marker labelling strategy for multiple donor DNAs, in which only the donor DNA with the lowest sgRNA efficiency was labelled. Combined with these strategies, we successfully developed a convenient method for cyclically coediting multiple genes in different filamentous fungi. In addition, diverse HRs resulted in a useful and convenient one‐step approach for gene functional study combining both gene disruption and complementation. This research provided both a useful one‐step approach for gene functional study and an efficient strategy for cyclically coediting multiple genes in filamentous fungi.

Underwater Image Restoration via Non-Convex Non-Smooth Variation and Thermal Exchange Optimization - Qingliang Jiao; Ming Liu; Pengyu Li; Liquan Dong; Mei Hui; Lingqin Kong; Yuejin Zhao (Journal of Marine Science and Engineering, 2021)
The quality of underwater images is an important problem for resource detection. However, the light scattering and plankton in water can impact the quality of underwater images. In this paper, a novel underwater image restoration based on non-convex, non-smooth variation and thermal exchange optimization is proposed. Firstly, the underwater dark channel prior is used to estimate the rough transmission map. Secondly, the rough transmission map is refined by the proposed adaptive non-convex non-smooth variation. Then, Thermal Exchange Optimization is applied to compensate for the red channel of underwater images. Finally, the restored image can be estimated via the image formation model. The results show that the proposed algorithm can output high-quality images, according to qualitative and quantitative analysis.

Two B-box domain proteins, BBX28 and BBX29, regulate flowering time at low ambient temperature in Arabidopsis - Mei-Jing Wang; Lan Ding; Xue-Huan Liu; Jian-Xiang Liu (Plant Molecular Biology, 2021)

Spatial prediction of soil calcium carbonate content based on Bayesian maximum entropy using environmental variables - Mei Shan; Shuang Liang; Hongchen Fu; Xiaoli Li; Yu Teng; Jingwen Zhao; Yaxin Liu; Chen Cui; Li Chen; Hai Yu; Shunbang Yu; Yanling Sun; et al. (Nutrient Cycling in Agroecosystems, 2021)

KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice - Hao-Ran Wang; Su-Wan Hu; Song Zhang; Yu Song; Xiao-Yi Wang; Lei Wang; Yang-Yang Li; Yu-Mei Yu; He Liu; Di Liu; Hai-Lei Ding; Jun-Li Cao (Neuroscience Bulletin, 2021)
Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury (CCI) in mice increased the firing activity and decreased the KCNQ channel-mediated M-currents in ventral tegmental area (VTA) DA neurons projecting to the nucleus accumbens (NAc). Chemogenetic inhibition of the VTA-to-NAc DA neurons alleviated CCI-induced thermal nociception. Opposite changes in the firing activity and M-currents were recorded in VTA DA neurons projecting to the medial prefrontal cortex (mPFC) but did not affect nociception. In addition, intra-VTA injection of retigabine, a KCNQ opener, while reversing the changes of the VTA-to-NAc DA neurons, alleviated CCI-induced nociception, and this was abolished by injecting exogenous BDNF into the NAc. Taken together, these findings highlight a vital role of KCNQ channel-mediated modulation of mesolimbic DA activity in regulating thermal nociception in the chronic pain state.

Spatial variation and fractionation of fluoride in tobacco-planted soils and leaf fluoride concentration in tobacco in Bijie City, Southwest China - Mei Wang; Long Zhang; Yanxiang Liu; Dan Chen; Lei Liu; Caibing Li; Kyong Ju Kang; Lingyu Wang; Zhenli He; Xiaoe Yang (Environmental Science and Pollution Research, 2021)

Isolation and Identification of Pseudomonas sp. Strain DY-1 from Agricultural Soil and Its Degradation Effect on Prometryne - Dong Liang; Ming-yue Ding; Chang-yixin Xiao; Ya-wen Shen; Yin-yue Wang; Hai-tao Li; Rong-mei Liu; Ji-guo Gao (Current Microbiology, 2021)

Puerhibacterium puerhi gen. nov., sp. nov., a novel member of the family Promicromonosporaceae, isolated from Pu-erh tea pile-fermentation - Rui-Juan Yang; De Zhou; Qiao-Mei Wang; Lu Han; Wen-Shu Peng; Li Liu; Xuan-Jun Wang; Liang Yan; Jie Lv; Jun Sheng (Archives of Microbiology, 2021)

Effect of fermentation bed on bacterial growth in the fermentation mattress material and cecum of ducks - Jian- mei Wang; Xin- meng Gan; Fa-jun Pu; Wan- xia Wang; Min Ma; Ling-li Sun; Ji-wei Hu; Bo Hu; Rong-ping Zhang; Li-li Bai; Liang Li; He-he Liu (Archives of Microbiology, 2021)

Clinical Pharmacology Regulatory Sciences in Drug Development and Precision Medicine: Current Status and Emerging Trends - Qi Liu; Mitra Ahadpour; Mitra Rocca; Shiew-Mei Huang (The AAPS Journal, 2021)

Design of Wave Glider Optimal Parameters Suitable for the Northwest Pacific Ocean, the North Indian Ocean, and the South China Sea - Xi Chen; Mei Hong; Shiqi Wu; Kefeng Liu; Kefeng Mao (Journal of Marine Science and Engineering, 2021)
To study the optimal design of Wave Glider parameters in the wave environment of the Northwest Pacific Ocean, the North Indian Ocean, and the South China Sea, the average velocity of a Wave Glider was taken as the evaluation criterion. Wave reanalysis data from ERA5 were used to classify the mean wave height and period into five types by the K-means clustering method. In addition, a dynamic model was used to simulate the influence of umbilical length, airfoil, and maximum limited angle on the velocity of the Wave Glider under the five types of wave element. The force of the wings was simulated using FLUENT as the model input. The simulation results show that (1) 7 m is the most suitable umbilical length; (2) a smaller relative thickness should be selected in perfect conditions; and (3) for the first type of wave element, 15° is the best choice for the maximum limited angle, and 20° is preferred for the second, third, and fourth types, while 25° is preferred for the fifth type.

Comparison of Nitrogen Loss Weight in Ammonia Volatilization, Runoff, and Leaching Between Common and Slow-Release Fertilizer in Paddy Field - Luying Chen; Xiaodong Liu; Zulin Hua; Hongqin Xue; Shengcheng Mei; Peng Wang; Shuwei Wang (Water, Air, & Soil Pollution, 2021)

Optimal Operation of a Parallel Multireservoir System for Flood Control using a Stagewise Compensation Method - Di Zhu; Yadong Mei; Xinfa Xu; Zhangjun Liu; Zhenhui Wu; Hao Cai (Water Resources Management, 2021)

Evaluation of the four potential Cretaceous-Paleogene (K-Pg) boundaries in the Nanxiong Basin based on evidences from volcanic activity and paleoclimatic evolution - Mengting Zhao; Mingming Ma; Mei He; Yudan Qiu; Xiuming Liu (Science China Earth Sciences, 2021)

Variation in rare earth element (REE), aluminium (Al) and silicon (Si) accumulation among populations of the hyperaccumulator Dicranopteris linearis in southern China - Wen-Shen Liu; Hong-Xiang Zheng; Chang Liu; Mei-Na Guo; Shi-Chen Zhu; Yue Cao; Rong-Liang Qiu; Jean Louis Morel; Antony van der Ent; Ye-Tao Tang (Plant and Soil, 2021)

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Microbiological profiles and antimicrobial resistance patterns of pediatric bloodstream pathogens in China, 2016–2018 - Yue Qiu; Junwen Yang; Yiping Chen; Jinhong Yang; Qingxiong Zhu; Chunhui Zhu; Shuangjie Li; Jing Liu; Chaomin Wan; Yu Zhu; Minxia Chen; Yi Xu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Supply chain carbon emission reductions and coordination when consumers have a strong preference for low-carbon products - Mei-lian Liu; Zong-huo Li; Sajid Anwar; Yun Zhang (Environmental Science and Pollution Research, 2021)

Altered resting-state functional networks in patients with hemodialysis: a graph-theoretical based study - Mei Jin; Liyan Wang; Hao Wang; Xue Han; Zongli Diao; Wang Guo; Zhenghan Yang; Heyu Ding; Zheng Wang; Peng Zhang; Pengfei Zhao; Han Lv; et al. (Brain Imaging and Behavior, 2021)

Effects of temperature and season on birds’ dawn singing behavior in a forest of eastern China - Sabah Mushtaq Puswal; Mei Jinjun; Fanglin Liu (Journal of Ornithology, 2021)

Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation - Xiaoli Liu; Yan Gu; Yaoyao Bian; Danhong Cai; Yu Li; Ye Zhao; Zhaofeng Zhang; Mei Xue; Liang Zhang (Apoptosis, 2021)
Acute promyelocytic leukemia (APL) is a blood system disease caused by the accumulation of a large number of immature blood cells in bone marrow. Although the introduction of all- trans retinoic acid (ATRA) and arsenic has reached a high level of complete remission rate and 5-year disease-free survival rate, the occurrence of various adverse reactions still severely affects the quality of life of patients. As a natural product, honokiol (HNK) has the advantages of low toxicity and high efficiency, and it is a potential drug for the treatment of cancer. Since cancer cells can escape apoptotic cell death through multiple adaptive mechanisms, HNK, a drug that induces cancer cell death in a nonapoptotic way, has attracted much interest. We found that HNK reduced the viability of human APL cell line (NB4 cells) by inducing paraptosis-like cell death. The process was accompanied by excessive reactive oxygen species (ROS), mitochondrial damage, endoplasmic reticulum stress, and increased microtubule-associated protein 1 light chain 3 (LC3) processing. The inactivation of proteasome activity was the main cause of misfolded and unfolded protein accumulation in endoplasmic reticulum, such as LC3II/I and p62. This phenomenon could be alleviated by adding cycloheximide (CHX), a protein synthesis inhibitor. We found that mTOR signaling pathway participated in paraptosis-like cell death induced by HNK in an autophagy-independent process. Moreover, the mitogen-activated protein kinase (MAPK) signaling pathway induced paraptosis of NB4 cells by promoting endoplasmic reticulum stress. In summary, these findings indicate that paraptosis may be a new way to treat APL, and provide novel insights into the potential mechanism of paraptosis-like cell death.

New secondary metabolite with cytotoxicity from spawning soft coral Asterospicularia laurae in Taiwan - Jui-Hsin Su; Chih-I Liu; Mei-Chin Lu; Chi-I Chang; Min-Ying Hsieh; Yu-Chi Lin; Chang-Feng Dai; Ya-Han Zhang; Zheng-Yu Lin; Yun-Sheng Lin (Natural Product Research, 2021)

Daily Prediction of the Arctic Sea Ice Concentration Using Reanalysis Data Based on a Convolutional LSTM Network - Quanhong Liu; Ren Zhang; Yangjun Wang; Hengqian Yan; Mei Hong (Journal of Marine Science and Engineering, 2021)
To meet the increasing sailing demand of the Northeast Passage of the Arctic, a daily prediction model of sea ice concentration (SIC) based on the convolutional long short-term memory network (ConvLSTM) algorithm was proposed in this study. Previously, similar deep learning algorithms (such as convolutional neural networks; CNNs) were frequently used to predict monthly changes in sea ice. To verify the validity of the model, the ConvLSTM and CNNs models were compared based on their spatiotemporal scale by calculating the spatial structure similarity, root-mean-square-error, and correlation coefficient. The results show that in the entire test set, the single prediction effect of ConvLSTM was better than that of CNNs. Taking 15 December 2018 as an example, ConvLSTM was superior to CNNs in simulating the local variations in the sea ice concentration in the Northeast Passage, particularly in the vicinity of the East Siberian Sea. Finally, the predictability of ConvLSTM and CNNs was analysed following the iteration prediction method, demonstrating that the predictability of ConvLSTM was better than that of CNNs.

Essential oil from Artemisia annua aerial parts: composition and repellent activity against two storage pests - Hong Liu; Shan-Shan Guo; Li Lu; Dian Li; Jun Liang; Zhong-Hui Huang; Yan-Mei Zhou; Wen-Juan Zhang; Shushan Du (Natural Product Research, 2021)

Thiazole-based and thiazolidine-based protein tyrosine phosphatase 1B inhibitors as potential anti-diabetes agents - Kexin Chen; Xu Yao; Ting Tang; Li-Mei Chen; Can Xiao; Jing-Yi Wang; Hong-Fei Chen; Zhong-Xing Jiang; Yi Liu; Xing Zheng (Medicinal Chemistry Research, 2021)

Neobacillus sedimentimangrovi sp. nov., a Thermophilic Bacterium Isolated from Mangrove Sediment - Rong Tang; Qi Zhang; Manik Prabhu Narsing Rao; Guo-Hong Liu; Jian-Mei Che; Min Lei; Bo Liu; Wen-Jun Li; Shun-Gui Zhou (Current Microbiology, 2021)

Influence of the roots of mixed-planting species on the shear strength of saline loess soil - Ya-bin Liu; Xia-song Hu; Dong-mei Yu; Hai-li Zhu; Guo-rong Li (Journal of Mountain Science, 2021)

Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway - Dan-Dan Tian; Min Wang; An Liu; Mei-Rong Gao; Chen Qiu; Wen Yu; Wen-Ju Wang; Kun Zhang; Le Yang; Yan-Yan Jia; Chang-Bin Yang; Yu-Mei Wu (Molecular Neurobiology, 2021)

Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway - Chen Qiu; Liu-Di Yang; Wen Yu; Dan-Dan Tian; Mei-Rong Gao; Wen-Ju Wang; Xu-Bo Li; Yu-Mei Wu; Min Wang (Metabolic Brain Disease, 2021)

Mechanisms of an extreme fog and haze event in the megacities of central and eastern China - Jianwei Yu; Yuan Wang; Mei Liu (Meteorology and Atmospheric Physics, 2021)

Chinese Cases of Metachromatic Leukodystrophy with the Novel Missense Mutations in ARSA Gene - Sifei Wu; Mei Hou; Yu Zhang; Jie Song; Ya Guo; Peipei Liu; Yedan Liu; Liping Yi; Xiaoyu Pan; Wei We; Zongbo Chen (Journal of Molecular Neuroscience, 2021)

The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish - Si-Lan Han; Yan Liu; Samwel M. Limbu; Li-Qiao Chen; Mei-Ling Zhang; Zhen-Yu Du (Fish Physiology and Biochemistry, 2021)

Identification of reproduction-related genes and pathways in the Culter alburnus H-P-G axis and characterization of their expression differences in malformed and normal gynogenetic ovaries - Yong Y. Jia; Mei L. Chi; Wen P. Jiang; Shi L. Liu; Shun Cheng; Jian B. Zheng; Zhi M. Gu (Fish Physiology and Biochemistry, 2021)

Molecular epidemiology and antifungal susceptibilities of Cryptococcus species isolates from HIV and non-HIV patients in Southwest China - Si-Ying Wu; Mei Kang; Ya Liu; Zhi-Xing Chen; Yu-Ling Xiao; Chao He; Ying Ma (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Evaluation of the combined effect of sodium persulfate and thermal hydrolysis on sludge dewatering performance - Kai Chen; Jingxin Liu; Simian Huang; Meng Mei; Si Chen; Teng Wang; Jinping Li (Environmental Science and Pollution Research, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

Maximum July–September temperatures derived from tree‐ring densities on the western Loess Plateau, China - Huiming Song; Ruochen Mei; Yu Liu; Daniel Nievergelt; Anne Verstege; Paolo Cherubini; Ruoshi Liu; Changfeng Sun; Qiang Li; Ling Chen; Xueli Zeng; Junqin Guo (International Journal of Climatology, 2021)
Tree‐ring densitometric studies conducted in semi‐arid regions are exceedingly rare. In this study, we evaluate a new maximum latewood density chronology from a collection of Picea purpurea trees growing in semi‐arid northwestern China for climatic reconstruction purposes. We find statistically significant correlations between annual maximum density variations and July–September maximum temperatures over the 1957–2014 calibration period. Using a linear model to transfer the density variations to temperature estimates, we then reconstruct maximum summer temperatures from 1840 to 2014. Statistical analyses and verification tests demonstrate that the resulting transfer function is both reliable and stable. The reconstructed temperature series shows strong inter‐annual and decadal variability. Several extremely cool and warm years are apparent on an inter‐annual scale, while three extended cool periods and a warm period are observed on a decadal scale. In addition, the reconstructed temperature series exhibits a pattern synchronous with that of the Indian monsoon index, as well as a moderate relationship to volcanic eruptions. This densitometric study reveals typical climatic variation characteristics and provides useful data for deepening our understanding of climate history in the semi‐arid regions of China.

The substrate‐dependent regulatory effects of the AfeI /R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles - Xue‐Yan Gao; Chang‐Ai Fu; Likai Hao; Xiu‐Feng Gu; Rui Wang; Jian‐Qiang Lin; Xiang‐Mei Liu; Xin Pang; Cheng‐Jia Zhang; Jian‐Qun Lin; Lin‐Xu Chen (Environmental Microbiology, 2021)
Summary A LuxI/R‐like quorum sensing (QS) system (AfeI/R) has been reported in the acidophilic and chemoautotrophic Acidithiobacillus spp. However, the function of AfeI/R remains unclear because of the difficulties in the genetic manipulation of these bacteria. Here, we constructed different afeI mutants of the sulfur‐ and iron‐oxidizer A . ferrooxidans , identified the N‐acyl homoserine lactones (acyl‐HSLs) synthesized by AfeI, and determined the regulatory effects of AfeI/R on genes expression, extracellular polymeric substance synthesis, energy metabolism, cell growth and population density of A . ferrooxidans in different energy substrates. Acyl‐HSLs‐mediated distinct regulation strategies were employed to influence bacterial metabolism and cell growth of A . ferrooxidans cultivated in either sulfur or ferrous iron. Based on these findings, an energy‐substrate‐dependent regulation mode of AfeI/R in A . ferrooxidans was illuminated that AfeI/R could produce different types of acyl‐HSLs and employ specific acyl‐HSLs to regulate specific genes in response to different energy substrates. The discovery of the AfeI/R‐mediated substrate‐dependent regulatory mode expands our knowledge on the function of QS system in the chemoautotrophic sulfur‐ and ferrous iron‐oxidizing bacteria, and provides new insights in understanding energy metabolism modulation, population control, bacteria‐driven bioleaching process, and the coevolution between the acidophiles and their acidic habitats.

Sesquiterpenoids and meroterpenoids from a mangrove derived fungus Diaporthe sp. SCSIO 41011 - Xiao-Wei Luo; Chun-Mei Chen; Kun-Long Li; Xiu-Ping Lin; Cheng-Hai Gao; Xue-Feng Zhou; Yong-Hong Liu (Natural Product Research, 2021)

Diterpenoid and triterpenoid glycosides from Clinopodium chinense - Ling-Xia Qu; Yong-Qiao Liu; Yang Wang; Hong Wang; Xue-Li Huang; Mei-Ling Zhang; Yong-Xiao Mou; Tun-Hai Xu; Yin-Di Zhu (Natural Product Research, 2021)

A holistic strategy for discovering structural analogues of drug residues in meat using characteristic structural fragments filtering by high-resolution Orbitrap mass spectrometry - Xiao-Min Liu; Xiu-Li Xu; Xue-Mei Nie; Xue-Song Feng; Feng Zhang (Food Additives & Contaminants: Part A, 2021)

QTL mapping and validation of bread wheat flag leaf morphology across multiple environments in different genetic backgrounds - Yang Tu; Hang Liu; Jiajun Liu; Huaping Tang; Yang Mu; Mei Deng; Qiantao Jiang; Yaxi Liu; Guoyue Chen; Jirui Wang; Pengfei Qi; Zhien Pu; et al. (Theoretical and Applied Genetics, 2021)

Elevated atmospheric CO 2 reduces yield‐scaled N 2 O fluxes from subtropical rice systems: Six site‐years field experiments - Zhisheng Yao; Rui Wang; Xunhua Zheng; Baoling Mei; Zaixing Zhou; Baohua Xie; Haibo Dong; Chunyan Liu; Shenghui Han; Zhongjun Xu; Klaus Butterbach‐Bahl; Jianguo Zhu (Global Change Biology, 2021)
Increasing levels of atmospheric CO 2 are expected to enhance crop yields and alter soil greenhouse gas fluxes from rice paddies. While elevated CO 2 ( ) effects on CH 4 emissions from rice paddies have been studied in some detail, little is known how might affect N 2 O fluxes or yield‐scaled emissions. Here, we report on a multi‐site, multi‐year in‐situ FACE (free‐air CO 2 enrichment) study, aiming to determine N 2 O fluxes and crop yields from Chinese subtropical rice systems as affected by . In this study, we tested various N fertilization and residue addition treatments, with rice being grown under either (+200 μmol/mol) or ambient control. Across the six site‐years, rice straw and grain yields under were increased by 9%–40% for treatments fertilized with ≥150 kg N/ha, while seasonal N 2 O emissions were decreased by 23%–73%. Consequently, yield‐scaled N 2 O emissions were significantly lower under . For treatments receiving insufficient fertilization (≤125 kg N/ha), however, no significant effects on N 2 O emissions were observed. The mitigating effect of upon N 2 O emissions is closely associated with plant N uptake and a reduction of soil N availability. Nevertheless, increases in yield‐scaled N 2 O emissions with increasing N surplus suggests that N surplus is a useful indicator for assessing N 2 O emissions from rice paddies. Our findings indicate that with rising atmospheric CO 2 soil N 2 O emissions from rice paddies will decrease, given that the farmers’ N fertilization is usually sufficient for crop growth. The expected decrease in N 2 O emissions was calculated to compensate 24% of the simultaneously observed increase in CH 4 emissions under . This shows that for an agronomic and environmental assessment of effects on rice systems, not only CH 4 emissions, but also N 2 O fluxes and yield‐scaled emissions need to be considered for identifying most climate‐friendly and economically viable options for future rice production.

A novel, validated, and plant height-independent QTL for spike extension length is associated with yield-related traits in wheat - Cong Li; Huaping Tang; Wei Luo; Xuemei Zhang; Yang Mu; Mei Deng; Yaxi Liu; Qiantao Jiang; Guoyue Chen; Jirui Wang; Pengfei Qi; Zhien Pu; et al. (Theoretical and Applied Genetics, 2020)

NAC103, a NAC family transcription factor, regulates ABA response during seed germination and seedling growth in Arabidopsis - Ling Sun; Li-Ping Liu; Ya-Zhen Wang; Lei Yang; Mei-Jing Wang; Jian-Xiang Liu (Planta, 2020)

Elevated plasma phage load as a marker for intestinal permeability in leukemic patients - Xue-rui Yin; Ping Liu; Xi Xu; Ying Xia; Kai-zhao Huang; Qiong-dan Wang; Mei-mei Lai; Qi-gui Yu; Xiao-qun Zheng (Medical Microbiology and Immunology, 2020)