Molecular weight, chain length distribution and long-term retrogradation of cassava starch modified by amylomaltase - Hua-Tsung Lin; An-I Yeh; Tuan-Hua David Ho; Min-Hsiung Pan; Shih Hsin Chen (Food Hydrocolloids, 2023)

The associations of particulate matter short-term exposure and serum lipids are modified by vitamin D status: A panel study of young healthy adults - Jia-Min Li; Han-Yu Yang; Si-Han Wu; Shyamali C. Dharmage; Bin Jalaludin; Luke D. Knibbs; Michael S. Bloom; Yuming Guo; Lidia Morawska; Joachim Heinrich; Yim Steve Hung Lam; Li-Zi Lin; et al. (Environmental Pollution, 2023)

Synthesis of N-doped sludge biochar using the hydrothermal route-enabled carbonization method for the efficient degradation of organic pollutants by peroxymonosulfate activation - Battuya Byambaa; Eun-Ju Kim; Mingizem Gashaw Seid; Byung-Min An; Jinsoo Cho; Shine Lin Aung; Kyung Guen Song (Chemical Engineering Journal, 2023)

Developing membrane reactors with suspended polyphthalocyanine nanoplatelets for upscaling syntheses of protein-polymer bioconjugates - Wen Fang Wei; Wan Lin Guo; Min Jian; Liu Shu Qin; Xue Li; Tao Cai (Chemical Engineering Journal, 2023)

Free-standing vertically aligned tin disulfide nanosheets for ultrasensitive aptasensor design toward Alzheimer’s diagnosis applications - Bayu Tri Murti; Yi-June Huang; Athika Darumas Putri; Chuan-Pei Lee; Chien-Ming Hsieh; Shih-Min Wei; Meng-Lin Tsai; Chih-Wei Peng; Po-Kang Yang (Chemical Engineering Journal, 2023)

Filling the gap between molecular and aggregate states: how does molecular packing affect photophysical properties? - Xu-Min Cai; Yuting Lin; Zhenguo Tang; Xuedan Zhang; Tianqi Mu; Shenlin Huang; Zheng Zhao; Ben Zhong Tang (Chemical Engineering Journal, 2023)

Intelligent films of marine polysaccharides and purple cauliflower extract for food packaging and spoilage monitoring - Han-Lun Huang; I-Lin Tsai; Chi Lin; Yu-Hao Hang; Yi-Cheng Ho; Min-Lang Tsai; Fwu-Long Mi (Carbohydrate Polymers, 2023)

Efficient activation of peroxydisulfate by a novel magnetic nanocomposite lignin hydrogel for contaminant degradation: Radical and nonradical pathways - Jiaqu Tan; Jinjin Wang; Zijun Tan; Min Yu; Zijiang Yang; Zongling Ren; Yongtao Li; Yulong Zhang; Xueming Lin (Chemical Engineering Journal, 2023)

Clustered regularly interspaced short palindromic repeats (CRISPR) technology and genetic engineering strategies for microalgae towards carbon neutrality: A critical review - Tse-Min Lee; Jia-Yi Lin; Tsung-Han Tsai; Ru-Yin Yang; I-Son Ng (Bioresource Technology, 2023)

Transcriptome analysis of PBMCs isolated from piglets treated with a miR-124 sponge construct identified miR124/IQGAP2/Rho GTPase as a target pathway support Salmonella Typhimurium infection - Tinghua Huang; Qi Tian; Zhen He; Hong Xiao; Chen Yuan; Zezhao Lin; Jing Yuan; Min Yao (Molecular Genetics and Genomics, 2023)

Expression profile of long non-coding RNAs in the intestine of black rockfish Sebastes schlegelii in response to Edwardsiella tarda infection - Xu Yan; Min Cao; Qiang Fu; Ning Yang; Ningning Wang; Lin Song; Chao Li (Journal of Oceanology and Limnology, 2023)

Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease - Li-Sha Ran; Ya-Zeng Wu; Yi-Wen Gan; Hong-Lian Wang; Li-Juan Wu; Chun-Mei Zheng; Yao Ming; Ran Xiong; Yong-Lin Li; Shi-Hang Lei; Xue Wang; Xiao-Qing Lao; et al. (Journal of Natural Medicines, 2023)
Excessive intrahepatocellular lipid accumulation or steatosis is caused by abnormal lipid metabolism and a common character of nonalcoholic fatty liver disease (NAFLD), which may progress into cirrhosis and hepatocellular cancer. Andrographolide (Andro) is the primary active ingredient extracted from Andrographis paniculata , showing a protective role against dietary steatosis with the mechanism not fully understood. In this study, we showed that administration of Andro (50, 100, and 200 mg/kg/day for 8 weeks, respectively) attenuated obesity and metabolic syndrome in high-fat diet (HFD)-fed mice with improved glucose tolerance, insulin sensitivity, and reduced hyperinsulinemia, hyperglycemia, and hyperlipidemia. HFD-fed mice presented hepatic steatosis, which was significantly prevented by Andro. In vitro, Andro decreased the intracellular lipid droplets in oleic acid-treated LO2 cells. The selected RT-PCR array revealed a robust expression suppression of the fatty acid transport proteins (FATPs) by Andro treatment. Most importantly, we found that Andro consistently reduced the expression of FATP2 in both the oleic acid-treated LO2 cells and liver tissues of HFD-fed mice. Overexpression of FATP2 abolished the lipid-lowering effect of Andro in oleic acid-treated LO2 cells. Andro treatment also reduced the fatty acid uptake in oleic acid-treated LO2 cells, which was blunted by FATP2 overexpression. Collectively, our findings reveal a novel mechanism underlying the anti-steatosis effect of Andro by suppressing FATP2-mediated fatty acid uptake, suggesting the potential therapeutic application of Andro in the treatment of NAFLD. Graphical abstract

Dual-response and lysosome-targeted fluorescent probe for viscosity and sulfur dioxide derivatives - Feng Li; Bang-Zhao Zhou; Wen Yao; Shou-Kang Sun; Jun-Ying Miao; Bao-Xiang Zhao; Zhao-Min Lin (Analytica Chimica Acta, 2023)

Control measure implications of COVID-19 infection in healthcare facilities reconsidered from human physiological and engineering aspects - Ying-Fei Yang; Yi-Jun Lin; Shu-Han You; Tien-Hsuan Lu; Chi-Yun Chen; Wei-Min Wang; Chung-Min Liao (Environmental Science and Pollution Research, 2022)

The biological transformation of ammonium and urea in a eutrophic estuarine system in Southern China - Jin-Ming Tang; Min Nina Xu; Yuxuan Lin; Huangxin Chen; Haoquan Jin; Li-Li Han; Wenbin Zou; Shuh-Ji Kao (Frontiers in Marine Science, 2022)
Estuaries channel large amounts of anthropogenic nitrogen (N) from continents to the offshore where productivity is widely limited by N and phosphorus. Ammonium and urea, two reduced forms of anthropogenic N commonly observed, are the preferred substrates for various microorganisms (e.g., uptake by phytoplankton or bacteria and oxidation by nitrifier). Yet, it remains underexplored how they transform and their concentrations vary during transport in the estuary which may influence the offshore microbial community. We applied 15 N isotope tracer incubation techniques to determine the two main bio-consumption processes, i.e., uptake and oxidation, of ammonium and urea, in the dark for the Jiulong River Estuary, a eutrophic estuary in southeastern China. Results showed that light penetration depth ranged from 0.8-3.3 m leaving 76% of estuary water bodies to stay in dark situations throughout a day. Ammonia oxidation, which favors dark conditions, dominates the estuarine regenerated-N cycle, showing the rank: ammonia oxidation > ammonium uptake >> urea uptake ≈ urea oxidation. By compiling the reported case studies, we found the relatively low ratio of urea oxidation to ammonia oxidation was accompanied by a relatively high ammonium concentration. Microorganisms’ high preference for ammonium over urea may lead to an inhibitory-like phenomenon. An analogous effect was evident by the increased urea uptake at downstream when ammonium was down to a few µM. The obstructed urea utilization resulted in 10 times longer lifetime for urea relative to ammonium (surface: 19 ± 9 days; bottom 12 ± 7 days). Such an inhibitory-like effect allows urea to be preserved in the estuary and allows urea to be transported farther offshore to stimulate microorganisms capable of utilizing urea, which may have significant impacts on offshore ecology.

An Underwater Inductive Power Transfer System with a Compact Receiver and Reduced Eddy Current Loss - Zhengchao Yan; Chenxu Zhao; Qianyu Hu; Min Wu; Lin Qiao; Kehan Zhang; Yuli Hu (Journal of Marine Science and Engineering, 2022)
Inductive power transfer (IPT) technology is widely used in autonomous underwater vehicles (AUVs) to achieve safety and flexibility. However, the eddy current loss (ECL) will be generated in the seawater due to the high-frequency alternating current in the transmitter and receiver. An underwater IPT system with a series-none (SN) compensation topology is proposed in this paper to achieve a compact receiver for AUVs and reduce the ECL. The analytical model of the IPT system is built to analyze its transfer performance. The phase difference between the transmitter and receiver current of the SN compensation topology is larger than 90° compared to that of the conventional series-series (SS) topology, which can significantly decrease the magnitude of the electric field caused by coil currents; thus, the eddy current loss is reduced. Moreover, the optimal load resistance of the seawater IPT system is lower than that in the air, and the SN compensation topology has a more compact receiver with no compensation capacitor in the receiving side, which can save the internal space in the AUVs. An experimental prototype based on the SN topology is built, and the experimental results have verified the analysis.

Prediction of Groundwater Quality Using Seven Types of First-Order Univariate Grey Model in the Chishan Basin, Taiwan - Tzu-Yi Pai; Ray-Shyan Wu; Ching-Ho Chen; Huang-Mu Lo; Terng-Jou Wan; Min-Hsin Liu; Wei-Cheng Chen; Yi-Ping Lin; Chun-Tse Hsu (Water, Air, & Soil Pollution, 2022)

Genome-wide association mapping of septoria nodorum blotch resistance in Nordic winter and spring wheat collections - Min Lin; Andrea Ficke; Jon Arne Dieseth; Morten Lillemo (Theoretical and Applied Genetics, 2022)
Key message A new QTL for SNB, QSnb.nmbu-2AS , was found in both winter and spring wheat panels that can greatly advance SNB resistance breeding Abstract Septoria nodorum blotch (SNB), caused by the necrotrophic fungal pathogen Parastagonospora nodorum , is the dominant leaf blotch pathogen of wheat in Norway. Resistance/susceptibility to SNB is a quantitatively inherited trait, which can be partly explained by the interactions between wheat sensitivity loci ( Snn ) and corresponding P. nodorum necrotrophic effectors (NEs). Two Nordic wheat association mapping panels were assessed for SNB resistance in the field over three to four years: a spring wheat and a winter wheat panel ( n = 296 and 102, respectively). Genome-wide association studies found consistent SNB resistance associated with quantitative trait loci (QTL) on eleven wheat chromosomes, and ten of those QTL were common in the spring and winter wheat panels. One robust QTL on the short arm of chromosome 2A, QSnb.nmbu-2AS , was significantly detected in both the winter and spring wheat panels. For winter wheat, using the four years of SNB field severity data in combination with five years of historical data, the effect of QSnb.nmbu-2AS was confirmed in seven of the nine years, while for spring wheat, the effect was confirmed for all tested years including the historical data from 2014 to 2015. However, lines containing the resistant haplotype are rare in both Nordic spring (4.0%) and winter wheat cultivars (15.7%), indicating the potential of integrating this QTL in SNB resistance breeding programs. In addition, clear and significant additive effects were observed by stacking resistant alleles of the detected QTL, suggesting that marker-assisted selection can greatly facilitate SNB resistance breeding.

Aloe polysaccharide promotes osteogenesis potential of adipose-derived stromal cells via BMP-2/Smads and prevents ovariectomized-induced osteoporosis - Xue-wei Yao; He-dong Liu; Mao-xian Ren; Tian-lin Li; Wen-kai Jiang; Zhi Zhou; Zhi-yi Liu; Min Yang (Molecular Biology Reports, 2022)
Background Aloe polysaccharide (AP) is a type of an active macromolecule of Aloe vera, which contributes to its function. However, whether AP possesses anti-osteoporosis properties is unknown. Methods Adipose-derived stromal cells were treated with different concentrations of AP. Early and late osteogenesis were, respectively, evaluated by ALP and Alizarin Red S staining. The effect of AP on the processes of adipogenesis inhibition in ADSCs was analyzed by oil red O staining. Western blot was used to assess the expression of osteogenic and adipogenic related factors. Then, Noggin was administered to further confirm the mechanism by which AP promotes the osteogenesis of ADSCs. Finally, 40 female SD rats were classified into a bilateral laparotomy group (Sham group) and three bilateral ovariectomy groups: OVX group, OVX + AP group, and OVX + AP + Noggin group. The bilateral rat femurs were collected to perform micro-CT scanning, HE, Masson trichrome, and Oil red O staining. Results The results indicated that AP could increase ALP expression and calcium deposition. Through molecular mechanisms, AP promotes the protein expression of COL1A1, OPN, and ALP in ADSCs, but downregulates the expression of PPARγ. Also, AP directs ADSCs’ fate by stimulating the BMP2/Smads signaling pathway. In vivo, the rat AP-treated had more trabecular bone than the OVX rat, indicating partial protection from cancellous bone loss after treatment with AP. Conclusion Our results show that AP may promote osteogenesis of ADSCs through BMP-2/Smads signaling pathway and inhibits lipogenic differentiation. Thus, AP might be a promising alternative medicine to treat postmenopausal osteoporosis.

Microplastic pollution and its impact on marine microbes in Zhanjiang, China - Qing-Lang Song; Fang-Hong Nie; Di-Hua Zhu; Yun-Li Wei; Min Zhang; Yao Hu; Meng-Meng Chen; Dan-Ju Kang; Zhi-Bao Chen; Hong-Ying Lin; Jin-Jun Chen (Journal of Coastal Conservation, 2022)

Breast cancer incidence in a national cohort of female workers exposed to special health hazards in Taiwan: a retrospective case-cohort study of ~ 300,000 occupational records spanning 20 years - Yun-Shiuan Chuang; Chun-Ying Lee; Pei-Chen Lin; Chih-Hong Pan; Hui-Min Hsieh; Chia-Fang Wu; Ming-Tsang Wu (International Archives of Occupational and Environmental Health, 2022)

Locus-level antagonistic selection shaped the polygenic architecture of human complex diseases - Weichen Song; Kai Yuan; Zhe Liu; Wenxiang Cai; Jue Chen; Shunying Yu; Min Zhao; Guan Ning Lin (Human Genetics, 2022)

Effect of empirical antifungal treatment on mortality in non-neutropenic critically ill patients: a propensity-matched retrospective cohort study - Yue Tang; Wenjing Hu; Shuangyan Jiang; Maoyu Xie; Wenying Zhu; Lin Zhang; Jing Sha; Tengfei Wang; Min Ding; Juan Zeng; Jinjiao Jiang (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Genomic Analysis and Molecular Characteristics in Carbapenem-Resistant Klebsiella pneumoniae Strains - Suying Zhao; Xingyi Qiu; Yiting Tan; Min Xu; Xiaotong Xu; Yulai Ge; Huiling Cao; Min Li; Yuxin Lin; Zhan Zhang; Lei Li; Qian Wu (Current Microbiology, 2022)

Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2 - Li-Min Xie; Yin-Fei Huang; Ye-Ling Liu; Jia-Qi Liang; Wei Deng; Geng-Ling Lin; Huan-Min Luo; Xu-Guang Guo (Biochemical Genetics, 2022)

Protective effect of ginsenoside Rd on military aviation noise-induced cochlear hair cell damage in guinea pigs - Xue-min Chen; Yu-hui Liu; Shuai-fei Ji; Xin-miao Xue; Lin-lin Wang; Min Zhang; Yao-ming Chang; Xiao-cheng Wang (Environmental Science and Pollution Research, 2022)

ACC deaminase-encoding Pseudomonas putida arrests seed germination: an alternative strategy for grass and weed control - Di Zhou; Jia-Ling Zhao; Rui Wang; Hai-Lin Wang; Daniela D. Herrera-Balandrano; Tang-Min Chen; Xiao-Feng Lu; Xu-Chu Duan; Mahdi Shahriar; Xin-Chi Shi; Pedro Laborda; Su-Yan Wang (Plant and Soil, 2022)

Pyroptosis in inflammation-related respiratory disease - Yuanyu Feng; Min Li; Xiaoting Yangzhong; Xifeng Zhang; Anju Zu; Yunjiao Hou; Lin Li; Shibo Sun (Journal of Physiology and Biochemistry, 2022)
Pyroptosis is commonly induced by the gasdermin (GSDM) family and is accompanied by the release of inflammatory cytokines such as IL-1β and IL-18. Recently, increasing evidence suggests that pyroptosis plays a role in respiratory diseases. This review aimed to summarize the roles and mechanisms of pyroptosis in inflammation-related respiratory diseases. There are several pathways involved in pyroptosis, such as the canonical inflammasome-induced pathway, non-canonical inflammasome-induced pathway, caspase-1/3/6/7/GSDMB pathway, caspase-8/GSDMC pathway, caspase-8/GSDMD pathway, and caspase-3/GSEME pathway. Pyroptosis may be involved in asthma, chronic obstructive pulmonary disease (COPD), lung cancer, acute lung injury (ALI), silicosis, pulmonary hypertension (PH), and tuberculosis (TB), in which the NLRP3 inflammasome-induced pathway is mostly highlighted. Pyroptosis contributes to the deterioration of asthma, COPD, ALI, silicosis, and PH. In addition, pyroptosis has dual effects on lung cancer and TB. Additionally, whether pyroptosis participates in cystic fibrosis (CF) and sarcoidosis or not is largely unknown, though the activation of NLRP3 inflammasome is found in CF and sarcoidosis. In conclusion, pyroptosis may play a role in inflammation-related respiratory diseases, providing new therapeutic targets.

Activity concentrations and bioconcentration factors (BCFs) of natural radionuclides (40 K, 226Ra, and 232Th) from cultivated substrates to mushrooms - Wei-Hsiang Huang; Chih-Chung Lin; Yung-Yu Liu; Chao-Min Huang; Yi-Lung Yeh; Ting-Chien Chen (Environmental Science and Pollution Research, 2022)

Local temperature increases reduce soil microbial residues and carbon stocks - Xiao‐Min Zeng; Jiao Feng; Dai‐Lin Yu; Shu‐Hai Wen; Qianggong Zhang; Qiaoyun Huang; Manuel Delgado‐Baquerizo; Yu‐Rong Liu (Global Change Biology, 2022)
Warming is known to reduce soil carbon (C) stocks by promoting microbial respiration, which is associated with the decomposition of microbial residue carbon (MRC). However, the relative contribution of MRC to soil organic carbon (SOC) across temperature gradients is poorly understood. Here, we investigated the contribution of MRC to SOC along two independent elevation gradients of our model system (i.e., the Tibetan Plateau and Shennongjia Mountain in China). Our results showed that local temperature increases were negatively correlated with MRC and SOC. Further analyses revealed that rising temperature reduced SOC via decreasing MRC, which helps to explain future reductions in SOC under climate warming. Our findings demonstrate that climate warming has the potential to reduce C sequestration by increasing the decomposition of MRC, exacerbating the positive feedback between rising temperature and CO 2 efflux. Our study also considered the influence of multiple environmental factors such as soil pH and moisture, which were more important in controlling SOC than microbial traits such as microbial life‐style strategies and metabolic efficiency. Together, our work suggests an important mechanism underlying long‐term soil C sequestration, which has important implications for the microbial‐mediated C process in the face of global climate change.

Two new physalins from Physalis alkekengi L. var. franchetii (Mast.) Makino - Jia-Min Sun; Ji-Xiang He; Min Huang; Hui-Xin Hu; Lin-Tao Xu; Kai-Li Fang; Xiao-Ning Wang; Tao Shen (Natural Product Research, 2022)

Bifunctional Ni@NiO catalyst supported on loofah sponge-derived carbon for electrocatalytic air oxidation of biorefractory pollutant in a coupling system - Min Sun; Xiong-Fei Tao; Sheng-Nan Tang; Jun Yu; Yan Wang; Lin-Feng Zhai (Environmental Science and Pollution Research, 2022)

Positive predictive value of noninvasive prenatal testing for sex chromosome abnormalities - Nan Guo; Meiying Cai; Min Lin; Huili Xue; Hailong Huang; Liangpu Xu (Molecular Biology Reports, 2022)
Background Early and intermediate serological screening cannot detect sex chromosome abnormalities. Currently, noninvasive prenatal testing (NIPT) is the only procedure available for screening such disorders; however, its use is controversial. Methods and Results A total of 47,855 pregnant women underwent NIPT at our referral center from January 2014 to December 2020. Of the 314 patients with a positive NIPT indicating sex chromosome abnormalities, 260 were screened via karyotype analysis and single nucleotide polymorphism (SNP) array after amniotic fluid extraction; 96 cases were confirmed. Karyotype analysis and SNP array were consistent in the diagnosis of 88 out of the 96 fetuses. The positive predictive value (PPV) for sex chromosome abnormalities was found to be 36.9%. The PPV in patients aged 30–34 years was significantly higher than that in patients aged < 30 years. No statistically significant difference was observed on the PPV among patients with or without previous adverse pregnancy outcomes. Moreover, 83 women carrying fetuses were diagnosed with a sex chromosome abnormality terminated their pregnancy. Conclusions Improvements in detection and analytical technologies are needed to increase the accuracy of sex chromosome abnormalities detection. Pregnant women with a positive NIPT for these abnormalities may require invasive diagnostic procedures such as karyotype analysis and SNP array for better genetic counseling.

Distribution characteristics of myxomycetes among substrates, study areas, and forest types in central China - Min Li; Yang Gao; Lei Yao; Gao-Wei Wang; Shu-Zhen Yan; Shuang-Lin Chen (Mycological Progress, 2022)

Gender disparities in incidence and projections of lung cancer in China and the United States from 1978 to 2032: an age-period-cohort analysis - Minghan Xu; Mandi Li; Jiao Pei; Chenyao Wu; Lin Jiang; Min Jiang; Cairong Zhu (Cancer Causes & Control, 2022)

A study of equatorial plasma bubble structure using VHF radar and GNSS scintillations over the low-latitude regions - Acharaporn Bumrungkit; Pornchai Supnithi; Susumu Saito; Lin Min Min Myint (GPS Solutions, 2022)
Ionospheric irregularities can cause detrimental effects on the global navigation satellite system (GNSS) signals, often in the form of rapid fluctuations in both amplitude and phase. Over the low-latitude regions, the equatorial plasma bubble (EPB) frequently arises after sunset, leading to GNSS scintillations since the signals propagate through ionospheric irregularities. The relationship between amplitude ionospheric scintillations (S4 index) on GNSS signals and EPB characteristics is presented. We investigate the geometrical relationship between backscatter echoes associated with the EPB and the multi-constellation and multi-frequency scintillations, specifically, GPS and Galileo constellations with L1/E1 and L5/E5a signals. By analyzing the GNSS scintillations along the GNSS signal paths, the GNSS ionospheric pierce points (IPPs) are mapped with S4 index at different altitudes and projected along the magnetic field line together with the backscatter echoes at the equatorial atmosphere radar (EAR), West Sumatra, Indonesia. Our results are obtained for moderate scintillation cases due to limited data available for this study. The results show the EPB impact ionospheric scintillations. The S4 index on the L5/E5a signal is more susceptible to scintillations than the L1/E1 signal. Moreover, we found a high correlation between EAR backscatter echoes and S4 values on both L1/E1 and L5/E5a at an altitude between 250 and 350 km, indicating that the EPB occurs on the bottomside of the ionosphere.

Cavitation–Silt Erosion Behavior and Failure Mechanism of an HVOF-Sprayed WC-Cr3C2-Ni Coating for Offshore Hydraulic Machinery - Jinran Lin; Sheng Hong; Yuan Zheng; Wei Sun; Zhengwei Zhang; Min Kang; Xiuqing Fu (Journal of Marine Science and Engineering, 2022)
WC-Cr3C2-Ni coatings are a vital class of hard ceramic/cermet coatings with potential applications as wear-resistant materials. However, their erosion wear behavior in 3.5 wt.% sodium chloride medium (SCM) remains largely unexplored. The present study investigated the cavitation–silt erosion (CSE) behavior in 3.5 wt.% SCM of WC-Cr3C2-Ni coatings sprayed with high-velocity oxygen–fuel (HVOF) under different flow velocities (FVs) and sand concentrations (SCs). Comparing the WC-Cr3C2-Ni coating with the 1Cr18Ni9Ti stainless steel, the first possessed superior CSE resistance in 3.5 wt.% SCM in a full range of FV and SC. Meanwhile, the coating appeared more influenced by FV and less influenced by SC, which was indicated by the fact that the amplification of VLR value (377.1%) when the FV ranged from 23.4 to 41.9 m·s−1 was larger than that (129.8%) when the SC increased from 10 kg·m−3 to 35 kg·m−3. With increasing FV and SC, the CSE process of the WC-Cr3C2-Ni coating in 3.5 wt.% SCM mainly included the discontinuous corrosion product films, erosion pits, fracturing of hard-phase grains, and micro-cutting of soft binder matrix, as well as crater formation and coating spalling.

Modeling of rupture using strong motion generation area: a case study of Hualien earthquake (Mw 6.1) occurred on April 18, 2019 - Saurabh Sharma; Anand Joshi; Sandeep; Che-Min Lin; Chun-Hsiang Kuo; Kuo-Liang Wen; Sandeep Singh; Mukat Lal Sharma; Mohit Pandey; Jyoti Singh (Acta Geophysica, 2022)

Horizontal and vertical heterogeneity of sediment microbial community in Site F cold seep, the South China Sea - Xinyi Zhai; Xiaochong Shi; Haojin Cheng; Peng Yao; Bin Zhao; Lin Chen; Jiwen Liu; Lei Cao; Minxiao Wang; Lulu Fu; Xiao-Hua Zhang; Min Yu (Frontiers in Marine Science, 2022)
Site F is the most vigorous cold seep known on the continental slope of the northern South China Sea. Up to now, the microbial community structures in sediments of Site F based on the high-throughput sequencing of the 16S rRNA genes have been studied extensively. However, few studies investigated the microbial community structures at fine vertical scales of Site F and control stations outside Site F. In this study, a comprehensive investigation of microbial communities in sediments of Site F along the depths varying from 0 to 24 cm below sea floor (cmbsf) of four sampling sites—SRS (Southern Reduced Sediment), NRS (Northern Reduced Sediment), Control 1 (close to Site F), and Control 2 (far from Site F)—was carried out. The high relative abundances of anaerobic methanotrophic archaea (ANME), Desulfobacterota [sulfate-reducing bacteria (SRB)], and Campylobacteria [sulfur-oxidizing bacteria (SOB)] in SRS and NRS indicated that these two sites were newborn cold seep sites compared with non-seep sites, Control 1, and Control 2. A positive correlation between ANME-1b, ANME-2, and SEEP-SRB and an enrichment of Sulfurovum and Methlomonadaceae were found in the surface sediments of both SRS and NRS, indicating that the processes of anaerobic oxidation of methane (AOM), sulfur oxidation, and sulfate reduction might occur in seep sites. SRS was enriched with ANME-1b and SEEP-SRB2 with a proposed sulfate-methane transition zone (SMTZ) approximately located at 8 cmbsf. The high abundance of ANME in SRS may due to the high concentration of methane. NRS was enriched with ANME-2, Desulfatiglans , Sulfurovum , and Methanosarcinaceae with a proposed SMTZ at about 10 cmbsf. According to the analyses of microbial community structure and environmental factors, NRS could be described as a notable cold seep reduced sediment site with low sulfate and high H 2 S that nourished abundant SEEP-SRB1, ANME-2, Methanosarcinales , and Sulfurovum , which showed similar distribution pattern. Our study expands the current knowledge on the differences of microbial communities in cold seep sites and non-seep sites and sheds light on the horizontal and vertical heterogeneity of sediment microbial community in Site F.

Distribution Characteristics and Ecological Risk Assessment of Heavy Metals in Marine Sediments of Binhai County, Jiangsu Province - Shu Chen; Min Xu; Dandan Cui; Lin Lv; Zaifeng Wang; Baiqiong Liu; Jing Wang (Journal of Marine Science and Engineering, 2022)
In recent years, research on heavy metals has become very popular, because the status of heavy metals can reflect the marine environment of a region. Based on this, this paper carries out the evaluation and analysis of heavy metals in marine sediments. Based on the content of the heavy metals in the coastal sediments of Binhai, Jiangsu, from coastal waters in the autumns of 2012, 2015, and 2018, the environmental quality was quantitatively evaluated using the geoaccumulation index and potential ecological risk. The sources of the heavy metals were identified by a multivariate analysis, and the changes over the years and the distribution characteristics were analyzed. Hg and Cr were at a clean grade, while other heavy metals contents indicated mild-to-moderate pollution in the three sets of monitoring data. The comprehensive ecological risk index assessment showed that Hg and Cd were at a moderate ecological risk level in the three sets of monitoring data. Overall, the study area exhibited a mild-to-moderate ecological risk level, with a continuously increasing trend. The overall content of heavy metal in this sea area is greatly affected by human activities, with high values occurring in ports, estuaries, and outer seas.

Shallow-water hydrothermal vent system as an extreme proxy for discovery of microbiome significance in a crustacean holobiont - Ling Chiu; Min-Chen Wang; Kuang-Yu Tseng; Chih-Lin Wei; Huei-Ting Lin; Shan-Hua Yang; Yung-Che Tseng (Frontiers in Marine Science, 2022)
The shallow-water hydrothermal vent (HV) system off Kueishan Island lies at the end of the Okinawa Trough to the northeast of Taiwan. Near its submarine vent openings, aperiodic vent discharges generate a dynamic acidic (pH 5.5-8.1) and sulfidic (9-3000 μM) ecosystem. The dominant metazoan in this unique environment is the brachyuran vent crab, Xenograpsus testudinatus , which has developed robust metabolic strategies and highly adaptive acid-base regulatory mechanisms to maintain its physiological homeostasis. X. testudinatus is considered a holobiont, but the symbiotic mechanisms underlying acid and sulfur tolerance in the host-microbe system remain largely unclear. In this study, we used LoopSeq long-read sequencing of the full-length 16S rRNA gene to identify the bacterial communities present in the gills and carapace surface of X. testudinatus . The alpha diversity analysis, Venn diagram, and principal coordinate analysis (PCoA) indicated that the gills and carapace surface exhibit different bacterial constituents. Further measurements of relative abundance, coupled with functional predictions and fluorescence in situ hybridization (FISH), revealed a predominance of Sulfurovum sp. NBC37-1, a key bacterium that can perform sulfur and hydrogen oxidation to support denitrification processes. Consequently, our findings suggest that the symbiotic bacteria may play a critical role in conferring the extraordinary acid and sulfur tolerances of X. testudinatus , allowing the crustacean holobiont to thrive in its ecological niche within one of the most extreme marine habitats on Earth.

Stochastic analysis of the variability of groundwater flow fields in heterogeneous confined aquifers of variable thickness - Ching-Min Chang; Chuen-Fa Ni; We-Ci Li; Chi-Ping Lin; I-Hsian Lee (Stochastic Environmental Research and Risk Assessment, 2022)

An automatic method to generate voxel-based absorbed doses from radioactivity distributions for nuclear medicine using generative adversarial networks: a feasibility study - Hui Lin; Xin Guo; Jia Jing; Xiaoli Mao; Yuanjun Yang; Min Hu (Physical and Engineering Sciences in Medicine, 2022)

The different effects of intramuscularly-injected lactate on white and brown adipose tissue in vivo - Yaqian Qu; Siyu Chen; Lei Zhou; Min Chen; Lin Li; Yihan Ni; Jingquan Sun (Molecular Biology Reports, 2022)

Application of the prenatal BACs-on-Beads™ assay for rapid prenatal detection of sex chromosome mosaicism - Min Zhang; LingJi Chen; Meihuan Chen; Yan Wang; Bin Liang; Na Lin; Xiaoqing Wu; Linshuo Wang; Liangpu Xu; Hailong Huang (Molecular Genetics and Genomics, 2022)
The prenatal BACs-on-Beads™ (BoBs) assay was introduced for rapid detection of abnormalities of chromosomes 13, 18, 21, X, and Y and specific nine significant microdeletion syndromes. The ability of prenatal BoBs to detect mosaicism ranged from 20 to 40%. However, there have been no prenatal studies of sex chromosome mosaicism in prenatal BoBs. Therefore, the present study was performed with an aim to uncover the detection level of sex chromosome mosaicism that application of prenatal BoBs assay, and then to assess the sensitivity of prenatal BoBs assay, thereby improving the prenatal diagnostic accuracy. A total of 31 samples of amniotic fluid (AF) and umbilical cord blood (UCB) for prenatal diagnosis were collected, and the results were confirmed through karyotyping, single nucleotide polymorphism microarray (SNP-array) and copy number variation sequencing (CNV-seq). 23 cases of sex chromosome mosaicism were prompted abnormal by prenatal BoBs, the minimum detection level of mosaicism was about 6% as detected by karyotype. The overall sensitivity of prenatal BoBs in the detection of sex chromosome mosaicism was 74.2% (23/31). This study evaluated the effectiveness of prenatal BoBs for detecting sex chromosome mosaicism in prenatal diagnosis, and the results will provide valuable information for genetic counseling.

Circ_0049472 regulates the damage of Aβ-induced SK-N-SH and CHP-212 cells by mediating the miR-107/KIF1B axis - Chaosheng Zeng; Huaijie Xing; Min Chen; Lin Chen; Pengxiang Li; Xiaowen Wu; Li Li (Experimental Brain Research, 2022)

Interdecadal change in the influence of El Niño in the developing stage on the central China summer precipitation - Lin Chen; Gen Li; Shang-Min Long; Chujie Gao; Zhiyuan Zhang; Bo Lu (Climate Dynamics, 2022)

ZAKβ Alleviates Oxidized Low-density Lipoprotein (ox-LDL)-Induced Apoptosis and B-type Natriuretic Peptide (BNP) Upregulation in Cardiomyoblast - Yueh-Min Lin; Jiro Hasegawa Situmorang; Jia-Zun Guan; Dennis Jine-Yuan Hsieh; Jaw-Ji Yang; Michael Yu-Chih Chen; Ching-Hui Loh; Chia-Hua Kuo; Shang-Yeh Lu; Ying-Ming Liou; Chih-Yang Huang (Cell Biochemistry and Biophysics, 2022)

Ancylostoma ceylanicum Infection in a Miniature Schnauzer Dog Breed - Xu-Hui Lin; Hai-Ming Cai; Zhuan-Qiang Yan; Shen-Quan Liao; Min-Na Lv; Cai-Yan Wu; Juan Li; Jun-Jing Hu; Wen-Wan Xiao; Jian-Fei Zhang; Nan-Shan Qi; Ming-Fei Sun (Acta Parasitologica, 2022)

Potential millennial‐scale avian declines by humans in southern China - Feng Dong; Qiang Zhang; Yi‐Lin Chen; Fu‐Min Lei; Shou‐Hsien Li; Fei Wu; Xiao‐Jun Yang (Global Change Biology, 2022)
Mounting observational records demonstrate human‐caused faunal decline in recent decades, while accumulating archaeological evidence suggests an early biodiversity impact of human activities during the Holocene. A fundamental question arises concerning whether modern wildlife population declines began during early human disturbance. Here, we performed a population genomic analysis of six common forest birds in East Asia to address this question. For five of them, demographic history inference based on 25–33 genomes of each species revealed dramatic population declines by 4‐ to 48‐fold over millennia (e.g. 2000–5000 thousand years ago). Nevertheless, summary statistics detected nonsignificant correlations between these population size trajectories and Holocene temperature variations, and ecological niche models explicitly predicted extensive range persistence during the Holocene, implying limited demographic consequence of Holocene climate change. Further analyses suggest high negative correlations between the reconstructed population declines and human disturbance intensities and indicate a potential driver of human activities. These findings provide a deep‐time and large‐scale insight into the recently recognized avifaunal decline and support an early origin hypothesis of human effects on biodiversity. Overall, our study sheds light on the current biodiversity crisis in the context of long‐term human–environment interactions and offers a multi‐evidential framework for quantitatively assessing the ecological consequences of human disturbance.

Coastal aquaculture farms for the sea cucumber Apostichopus japonicus provide spawning and first-year nursery grounds for wild black rockfish, Sebastes schlegelii: A case study from the Luanhe River estuary, Bohai bay, the Bohai Sea, China - Min Xu; Zun-li Qi; Zun-lei Liu; Wei-min Quan; Qi Zhao; Yun-ling Zhang; Hui Liu; Lin-lin Yang (Frontiers in Marine Science, 2022)
Aquaculture farms are known to attract wild organisms from nearby areas. Sea cucumber Apostichopus japonicus aquaculture farms in Bohai Bay, the Bohai Sea, China, might provide spawning and nursery grounds for wild black rockfish Sebastes schlegelii populations. To identify the above, we studied the variation in the numbers of S. schlegelii larvae (and length-categories as a percentage of the natural population) via ichthyoplankton surveys by months from January to October 2020, and assessed the food web structure and energy flow distribution of the farm and trophic links of S. schlegelii natural stock by using Ecopath modeling in July 2016 to August 2017. Larvae with a length between 3.90-5.80 mm were observed in the farm in May 2020, the juveniles with an estimated trophic level of 4.31. Juveniles used the farms as first-year nursery ground, and then they swam into deeper waters in August of the following year. MTI analysis showed increasing biomass of S. schlegelii might result in a decrease in the biomass of crustacea, and had positive and negative impacts on mollusk and Hexagrammos otakii biomass. We argued that aquacultural infrastructures constructed by artificial reefs could be used as a fisheries management tool to enhance S. schlegelii stocks and that monitoring of other marine organisms, such as oysters, Rapana venosa , Charybdis japonica , and Asterias spp. etc., was necessary to maintain sustainable exploitations of aquacultural farm ecosystems. A paucity of knowledge surrounding the interactions between aquaculture farms and wild organisms needs furthermore researches.

SGBNet: An Ultra Light-weight Network for Real-time Semantic Segmentation of Land Cover - Kai Pang; Liguo Weng; Yonghong Zhang; Jia Liu; Haifeng Lin; Min Xia (International Journal of Remote Sensing, 2022)

Cloud/shadow segmentation based on multi-level feature enhanced network for remote sensing imagery - Shoukuan Miao; Min Xia; Ming Qian; Yonghong Zhang; Jia Liu; Haifeng Lin (International Journal of Remote Sensing, 2022)

Integrated Analyses of miRNome and Transcriptome Reveal the Critical Role of miRNAs Toward Heat Stress Response in Isochrysis galbana - Jia-Yi Cao; Si-Min Xu; Ying-Ying Wang; Xie-Dan Long; Shuo-Nan Ma; Cheng-Xu Zhou; Ji-Lin Xu; Xiao-Jun Yan (Marine Biotechnology, 2022)

Nematicidal activity of volatile organic compounds produced by Bacillus altitudinis AMCC 1040 against Meloidogyne incognita - Lin Ye; Jian-Yu Wang; Xiao-Fang Liu; Qi Guan; Nong-Xiao Dou; Jian Li; Qian Zhang; Yan-Ming Gao; Min Wang; Jian-She Li; Bo Zhou (Archives of Microbiology, 2022)

Effectiveness of allyl isothiocyanate microencapsulated in polyethylene as a repellent against Solenopsis invicta (Hymenoptera: Formicidae) infestation of corrugated cardboard boxes in field experiment - Yoshiaki Hashimoto; Hironori Sakamoto; Hiromi Asai; Masamitsu Yasoshima; Hui-Min Lin; Koichi Goka (Applied Entomology and Zoology, 2022)
Solenopsis invicta Buren (Hymenoptera: Formicidae; red imported fire ant) is an invasive species in several parts of the world. A major contributor to the spread of S. invicta is infested shipping containers. The vapor of allyl isothiocyanate (AITC), a naturally occurring organosulfur compound, is highly toxic to S. invicta ; however, AITC is highly volatile. Microencapsulation of AITC in polyethylene (PE) resin slows the release of AITC, making it a potentially useful material for preventing S. invicta infestations. Here, we examined the efficacy of AITC microencapsulated in PE (mAITC) as a repellent against S. invicta infestation of cardboard boxes, a common containerized cargo. Using baited cardboard boxes, we found that the number of S. invicta individuals entering boxes containing an mAITC sheet was significantly less than that entering boxes without an mAITC sheet. When a PE cover, which is often used to protect carboard boxes during shipping, was used, vapor concentrations of AITC inside the boxes were increased and the number of S. invicta individuals entering the boxes was reduced almost to zero. These findings indicate that mAITC sheeting, especially in combination with a PE cover, is a promising material for the protection of containerized cardboard-box cargo against S. invicta infestation.

Assessing the effect of probiotics on tilapia lake virus‐infected tilapia: Transmission and immune response - Ying‐Fei Yang; Jidapa Yamkasem; Win Surachetpong; Yi‐Jun Lin; Shu‐Han You; Tien‐Hsuan Lu; Chi‐Yun Chen; Wei‐Min Wang; Chung‐Min Liao (Journal of Fish Diseases, 2022)
Probiotics have been used to alleviate disease transmission in aquaculture. However, there are limited studies on probiotic use in modulating tilapia lake virus (TiLV). We assessed commercially available probiotic supplements used in TiLV‐infected tilapia and performed mortality and cohabitation assays. We developed a mechanistic approach to predict dose–response interactions of probiotic effects on mortality and immune gene response. We used a susceptible–infected–mortality disease model to assess key epidemiological parameters such as transmission rate and basic reproduction number ( R 0 ) based on our viral load dynamic data. We found that the most marked benefits of probiotics are significantly associated with immune system enhancements (~30%) and reductions in disease transmission (~80%) and R 0 (~70%) in tilapia populations, resulting in a higher tolerance of farming densities (~400 fold) in aquaculture. These findings provide early insights as to how probiotic use‐related factors may influence TiLV transmission and the immune responses in TiLV‐infected tilapia. Our study facilitates understanding the mode of action of probiotics in disease containment and predicting better probiotic dosages in diet and supplements to achieve the optimal culturing conditions. Overall, our analysis assures that further study of rationally designed and targeted probiotics, or mechanistic modelling is warranted on the basis of promising early data of this approach.

Post-transcriptional control of bacterial nitrogen metabolism by regulatory noncoding RNAs - Yueyue Han; Chao Li; Yongliang Yan; Min Lin; Xiubin Ke; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2022)
Nitrogen metabolism is the most basic process of material and energy metabolism in living organisms, and processes involving the uptake and use of different nitrogen sources are usually tightly regulated at the transcriptional and post-transcriptional levels. Bacterial regulatory noncoding RNAs are novel post-transcriptional regulators that repress or activate the expression of target genes through complementarily pairing with target mRNAs; therefore, these noncoding RNAs play an important regulatory role in many physiological processes, such as bacterial substance metabolism and stress response. In recent years, a study found that noncoding RNAs play a vital role in the post-transcriptional regulation of nitrogen metabolism, which is currently a hot topic in the study of bacterial nitrogen metabolism regulation. In this review, we present an overview of recent advances that increase our understanding on the regulatory roles of bacterial noncoding RNAs and describe in detail how noncoding RNAs regulate biological nitrogen fixation and nitrogen metabolic engineering. Furthermore, our goal is to lay a theoretical foundation for better understanding the molecular mechanisms in bacteria that are involved in environmental adaptations and metabolically-engineered genetic modifications.

Chlorophyll fluorescence and grain filling characteristic of wheat (Triticum aestivum L.) in response to nitrogen application level - Hafeez Noor; Min Sun; Hussah I. M. Algwaiz; Alam Sher; Sajid Fiaz; KOTB A. Attia; Shabir Hussain Wani; Muneera D. F. AlKahtani; Latifa Al Husnain; Wen Lin; Zhiqiang Gao (Molecular Biology Reports, 2022)

LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p - Shichao Li; Lingyan Zhang; Jiajie Lin; Achou Su; Xiyun Liu; Jingge Zhang; Xiaohui Xian; Yuyan Hu; Wenbin Li; Shaoguang Sun; Min Zhang (Molecular Neurobiology, 2022)
Long noncoding RNAs (lncRNAs) play an important regulatory role in various diseases. However, the role of lncRNAs in brain ischemic tolerance (BIT) induced by cerebral ischemic preconditioning (CIPC) is still unknown. The lncRNA profile of rat cortical astrocytes pretreated with ischemic preconditioning was analyzed by high-throughput sequencing. The results of Cell-Counting Kit-8 (CCK-8) assay showed that a novel lncRNA, NONRATT009133.2, which we referred to as brain ischemia–related factor (BIRF), was highly correlated with BIT. Through bioinformatics analysis, we predicted that BIRF, miR-330-5p, and GLT-1 (also named Slc1a2 ) might constitute a ceRNA regulatory network in the induction of BIT. We found that BIRF was upregulated by CIPC, which promoted GLT-1 expression and BIT induction. BIRF could directly bind to miR-330-5p. Furthermore, miR-330-5p directly targeted GLT-1, and miR-330-5p inhibited both GLT-1 expression and BIT induction in vitro and in vivo. Moreover, BIRF acts as a molecular sponge to competitively bind to miR-330-5p with GLT-1 mRNA, while the miR-330-5p inhibitor reversed all the effects of BIRF siRNA on GLT-1 expression and neuronal vitality. Taken together, our results demonstrate the important roles of the BIRF/miR-330-5p/GLT-1 axis in the induction of BIT by CIPC. BIRF may be a potentially effective therapeutic strategy against stroke injury.

Fine particulate matter measured by satellites predicts the risk of age-related macular degeneration in a longitudinal cohort study - Chung-Ling Liang; Chi-Min Wang; Chau-Ren Jung; Ya-Chu Chang; Chun-Ju Lin; Yu-Ting Lin; Bing-Fang Hwang (Environmental Science and Pollution Research, 2022)

Associations Between Plasma Metals and Cognitive Function in People Aged 60 and Above - Junling Zhang; Qiumei Liu; Min Xu; Jiansheng Cai; Yanfei Wei; Yinxia Lin; Xiaoting Mo; Shenxiang Huang; Shuzhen Liu; Chunbao Mo; Tingyu Mai; Dechan Tan; et al. (Biological Trace Element Research, 2022)

Influence of asymmetric blockage of the drainage system of a deep-buried tunnel on water gushing - He-lin Fu; Peng-tao An; Yi-min Wu; Jie Li; Long Chen (Journal of Mountain Science, 2022)

Insight rifampicin-resistant (rpoB) mutation in Pseudomonas stutzeri leads to enhance the biosynthesis of secondary metabolites to survive against harsh environments - Khandakar Mohiul Alam; Yongliang Yan; Min Lin; Md. Ariful Islam; Ahmed Gaber; Akbar Hossain (Archives of Microbiology, 2022)

Electrospun Polysaccharides for Periodontal Tissue Engineering: A Review of Recent Advances and Future Perspectives - Jiao Wang; Yi Chen; Jialing Li; Zhen Chen; Min Fan; Fanjing Lin; Yonglin Xie (Annals of Biomedical Engineering, 2022)

Genetic Diversity Evaluation and Population Structure Analysis of Red Swamp Crayfish (Procambarus clarkii) from Lakes and Rice Fields by SSR Markers - Xin-Fen Guo; Min Liu; Yu-Lin Zhou; Wen-Yu Wei; Zhi Li; Li Zhou; Zhong-Wei Wang; Jian-Fang Gui (Fishes, 2022)
The red swamp crayfish (Procambarus clarkii) is an important aquatic animal and has developed as a popular aquaculture species in China. In this study, a total of 72,839 SSR motifs were identified from transcriptional data, and 20 microsatellite markers of them were finally developed to assess the genetic diversities of seven wild populations from natural lakes and nine cultured populations from rice fields. Genetic diversity was slightly higher in the cultured populations than in the wild populations. The degree of genetic differentiation between cultured populations is slight, while a moderate to a large degree of genetic differentiation between wild populations and most of the variations occurred within individuals (79%). The analysis of cluster, principal coordinate analysis and STRUCTURE were similar, and they showed that isolation-by-distance pattern was not significant. The microsatellite markers developed in this study can not only be used for genetic monitoring of population but also provide important information for the management of breeding and cultured population in red swamp crayfish.

Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α -glucosidase inhibitory activity - Min Song; Tong Xiao; Qiu-Shuang Wu; Hang Fai Kwok; Ging Chan; Li-Gen Lin; Xiao-Qi Zhang; Wen-Cai Ye; Sheng-Jiang He; Qing-Wen Zhang (Natural Product Research, 2022)

Lactobacillus plantarum PS128 Promotes Intestinal Motility, Mucin Production, and Serotonin Signaling in Mice - Chih-Ming Chen; Chien-Chen Wu; Chin-Lin Huang; Min-Yu Chang; Shih-Hsuan Cheng; Ching-Ting Lin; Ying-Chieh Tsai (Probiotics and Antimicrobial Proteins, 2022)
Lactobacillus plantarum PS128 has been reported as a psychobiotic to improve mental health through the gut–brain axis in experimental animal models. To explore its mechanism of action in the gut, this study aimed to analyze the effects of L. plantarum PS128 ingestion on naïve and loperamide (Lop)-induced constipation mice. We found that, in the two mouse models, the weight, number, and water content of feces in the L. plantarum PS128 group were higher than those in the vehicle control group. Histological observation revealed that L. plantarum PS128 increased the level of colonic mucins including the major mucin MUC2. In addition, the charcoal meal test showed that L. plantarum PS128 significantly increased the small intestine transit in naïve mice, but not in the Lop-treated mice. Since intestinal serotonin has been found to modulate motility, we further analyzed the expression of genes related to serotonin signal transduction in the small intestine of naïve mice. The results showed that L. plantarum PS128 significantly altered the expression levels of Tph1 , Chga , Slc6a4 , and Htr4 , but did not affect the expression levels of Tph2 , Htr3a , and Maoa . Furthermore, immunohistochemistry revealed that L. plantarum PS128 significantly increased the number of serotonin-containing intestinal cells in mice. Taken together, our results suggest that L. plantarum PS128 could promote intestinal motility, mucin production, and serotonin signal transduction, leading to a laxative effect in mice.

Transcriptome Changes Induced by Botrytis cinerea Stress and Weighted Gene Co-expression Network Analysis (WGCNA) in Actinidia chinensis - Zhe-Xin Li; Wen-Lin Zhang; Deng-Wei Jue; Xia Liu; Yu-Song Jiang; Jian-Min Tang (Plant Molecular Biology Reporter, 2022)

Correction to: Publication characteristics, topic trends and knowledge domains of karst ecological restoration: a bibliometric and knowledge mapping analysis from 1991 to 2021 - Kehui Liu; Xiaojin Guan; Guangluan Li; Min Duan; Yi Li; Yanyan Hong; Meimei Lin; Rongxin Fu; Fangming Yu (Plant and Soil, 2022)

Publication characteristics, topic trends and knowledge domains of karst ecological restoration: a bibliometric and knowledge mapping analysis from 1991 to 2021 - Kehui Liu; Xiaojin Guan; Guangluan Li; Min Duan; Yi Li; Yanyan Hong; Meimei Lin; Rongxin Fu; Fangming Yu (Plant and Soil, 2022)

Moss biocrusts buffer the negative effects of karst rocky desertification on soil properties and soil microbial richness - Cai Cheng; Yujie Li; Mingzhong Long; Min Gao; Yuandong Zhang; Jiayu Lin; Xiaona Li (Plant and Soil, 2022)

Use of piggyBac Transposon System Constructed Murine Breast Cancer Model for Reporter Gene Imaging and Characterization of Metastatic Tumor Cells - Ying-Ling Chen; Yung-Cheng Wang; Kuei-Yuan Hou; Min-Ying Lin; Yu-Chuan Lin; Hui-Yen Chuang; Yi-Jang Lee (Journal of Medical and Biological Engineering, 2022)

Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2 - Jinbao Zong; Yanping Zhang; Fenfen Guo; Changyuan Wang; Hong Li; Gaoyang Lin; Wenqing Jiang; Xiaoping Song; Xiufang Zhang; Feng Huang; Min Qi; Xin Zheng (Journal of Applied Genetics, 2022)

Responses of photosynthesis, antioxidant enzymes, and related gene expression to nicosulfuron stress in sweet maize (Zea mays L.) - Zhen-Xing Wu; Ning-Wei Xu; Min Yang; Xiang-Ling Li; Jin-Ling Han; Xiao-Hu Lin; Qing Yang; Gui-Hua Lv; Jian Wang (Environmental Science and Pollution Research, 2022)

Global burden of chronic obstructive pulmonary disease attributable to ambient particulate matter pollution and household air pollution from solid fuels from 1990 to 2019 - Yinglin Wu; Shiyu Zhang; Bingting Zhuo; Miao Cai; Zhengmin Min Qian; Michael G. Vaughn; Stephen Edward McMillin; Zilong Zhang; Hualiang Lin (Environmental Science and Pollution Research, 2022)

Effects of Microplastics on Microbial Community in Zhanjiang Mangrove Sediments - Meng-Meng Chen; Fang-Hong Nie; Aftab Qamar; Di-hua Zhu; Yao Hu; Min Zhang; Qing-Lang Song; Hong-Ying Lin; Zhi-Bao Chen; Su-Qing Liu; Jin-Jun Chen (Bulletin of Environmental Contamination and Toxicology, 2022)

Shinella oryzae sp. nov., a novel zearalenone-resistant bacterium isolated from rice paddy soil - Ruyu Gao; Juan Zheng; Wei Lu; Xiubin Ke; Ming Chen; Min Lin; Wei Zhang; Zhengfu Zhou (Antonie van Leeuwenhoek, 2022)

Berberisides A-D: three novel prenylated benzoic acid derivatives and a clerodane glycoside from Berberis tsarica aherndt. - Zhao-Yue Dong; Qing-Hong Zeng; Lin Wei; Xin Guo; Yan Sun; Fan-Cheng Meng; Guo-Wei Wang; Xiao-Zhong Lan; Zhi-Hua Liao; Min Chen (Natural Product Research, 2022)

Effects of Recovery Ratio on the Fracture Evolution of the Overburden Pressure-Relief Gas Migration Channel for a Fully Mechanized Working Face - Pengxiang Zhao; Jianan Wang; Shugang Li; Hao Li; Lei Qin; Haifei Lin; Chi-Min Shu; Bin Laiwang; Yongyong Jia; Zongyong Wei; Wenbo Pei (Natural Resources Research, 2022)

MiR-361-3p alleviates cerebral ischemia–reperfusion injury by targeting NACC1 through the PINK1/Parkin pathway - Xihong Ye; Hua Song; Huimin Hu; Chunli Zhou; Qinyi Chen; Lin Hong; Min Huang; Hongfei Zhu (Journal of Molecular Histology, 2022)

The RNA-binding protein SND1 promotes the degradation of GPX4 by destabilizing the HSPA5 mRNA and suppressing HSPA5 expression, promoting ferroptosis in osteoarthritis chondrocytes - Min Lv; Yuanzhen Cai; Weikun Hou; Kan Peng; Ke Xu; Chao Lu; Wenxing Yu; Weisong Zhang; Lin Liu (Inflammation Research, 2022)

Effects of Environmental and Spatial Variables on Bacteria in Zhanjiang Mangrove Sediments - Di-Hua Zhu; Qing-Lang Song; Fang-Hong Nie; Wan Wei; Meng-Meng Chen; Min Zhang; Hong-Ying Lin; Dan-Ju Kang; Zhi-Bao Chen; Anthony G. Hay; Jin-Jun Chen (Current Microbiology, 2022)

Production of sesquiterpene patchoulol in mitochondrion-engineered Saccharomyces cerevisiae - Xin-Yi Tao; Yang-Chen Lin; Feng-Qing Wang; Qing-Hai Liu; Yu-Shu Ma; Min Liu; Dong-Zhi Wei (Biotechnology Letters, 2022)

Selenium Alleviates Inflammation in Staphylococcus aureus-Induced Mastitis via MerTK-Dependent Activation of the PI3K/Akt/mTOR Pathway in Mice - Si-jie Chen; Chen-yuan Zhang; Di Yu; Chang-jie Lin; Hao-jun Xu; Chang-min Hu (Biological Trace Element Research, 2022)

Sterols and triterpenoids from Ganoderma lucidum and their reversal activities of tumor multidrug resistance - Min Wu; Cui-e Shen; Qiao-fa Lin; Jin-yi Zhong; Yan-fei Zhou; Ben-chen Liu; Jian-hua Xu; Zhi-qiang Zhang; Peng Li (Natural Product Research, 2022)

Nitrogen Fertilization and Precipitation Affected Wheat Nitrogen Use Efficiency and Yield in the Semiarid Region of the Loess Plateau in China - Jie Ren; Aixia Ren; Wen Lin; Hafeez Noor; Shahbaz Khan; Shifeng Dong; Min Sun; Zhiqiang Gao (Journal of Soil Science and Plant Nutrition, 2022)

Spatiotemporal distribution and the passive dispersal of fungal spores through HVAC systems - Wan-Rou Lin; Yung-Hung Ho; Wai Kwan Lee; Hsuan-Min Cheng; Pi-Han Wang (Aerobiologia, 2022)

Morphological and Molecular Characterization of Paragonimus skrjabini Complex from Yunnan, China: A Brief Report - Qiu-Hong Shu; Shu-De Li; Ming Tian; Yong Meng; Shu-Mei-Qi He; Min Zhu; Miao-Miao Wang; Wen-Lin Wang (Acta Parasitologica, 2022)
Purpose To perform environmental sampling and molecular identification of Paragonimus in endemic regions, which may help in minimizing transmission among humans. Methods Mountain crabs from the genus Potamiscus were collected and the encysted metacercariae were extracted and subjected to morphological identification, followed by animal inoculation in Sprague–Dawley (SD) rats. After 112 days of infection, animals were killed and adult worms were extracted from lungs and muscles. The morphology of adult worms was characterized by microscopy and molecular identification was done by polymerase chain reaction, followed by sequencing of cox1 and ITS2 genes. Phylogenetic analysis was done by maximum parsimony method. Results A total of 447 crabs were captured from the streams of Tongchang Town, Jinping County, Yunnan Province, China. The infection rate was found to be 41% (186 out of 447 crabs). The metacercariae of Paragonimus skrjabini was identified by the characteristics round or spherical encysted form measuring 410 to 460 × 400 to 460 µm. After animal infection in SD rats, adults were presumptively confirmed to be P. skrjabini , which was also confirmed by gene amplification and sequence analysis of cox1 and ITS2 regions. Paragonimus skrjabini clustered with previously reported P. skrjabini from Yunnan and Vietnam. The confidence values of their branches were > 95%. Phylogenetic analysis of the ITS2 region revealed two distinct clusters with distinct geographical grouping. Phylogenetic analysis with the combined data sets reiterated the geographical grouping with P. skrjabini from Yunnan clustering with strains from Vietnam. Conclusion Metacercariae of P. skrjabini was discovered in freshwater crabs in Yunnan province, China, and the strains were phylogenetically related to P. skrjabini from Vietnam.

A Challenge to Conventional Fish Meal: Effects of Soy Protein Peptides on Growth, Histomorphology, Lipid Metabolism and Intestinal Health for Juvenile Pompano Trachinotus ovatus - Huaxing Lin; Beiping Tan; Gyan Watson Ray; Min Zeng; Mei Li; Shuyan Chi; Qihui Yang (Frontiers in Marine Science, 2022)
This experiment was conducted to assess the possibility of replacing fish meal (FM) with soy protein peptide (SPP) at different levels—0% (FM), 14.29% (S5), 28.57% (S10), 57.14% (S20), 71.42%(S25)—and its effects on growth, histology, gene expression related to liver lipid metabolism and intestinal immunity in juvenile pompano Trachinotus ovatus (initial mean weight = 39.88 ± 0.15 g). 600 healthy and uniformed-size fish were distributed to five groups of three replicates, each with 40 fish in each floating cage and fed twice daily for 8 weeks. Results showed that no significant difference in the growth was observed with SPP replacing FM ( P > 0.05). Serum glutathione peroxidase activity in the S10 group was significantly higher than that in the FM group, and serum malondialdehyde content significantly decreased ( P < 0.05). SPP significantly improved intestinal immunity by increasing alkaline phosphatase and lysozyme activities and up-regulating interleukin 10 and complement 4 mRNA levels while simultaneously decreasing triglyceride and total cholesterol content and down-regulating interleukin 1β mRNA expression. Villus length and muscle thickness in the S10 group were significantly higher than those in the FM group ( P < 0.05). SPP significantly improved liver fat metabolism by increasing carnitine palmitoyl transferase I mRNA levels, and down-regulating fatty acid synthesis mRNA expression ( P < 0.05). In summary, SPP substitution for FM promoted intestinal health, liver lipid metabolism and reduced liver fat accumulation for juvenile pompano T. ovatus , with no significant effect on growth performance. Based on the second-order polynomial analysis model of LYZ activity, the optimal replacement SPP level for juvenile pompano T. ovatus was 11.82%.

Synthesis, antifungal activity and 3D-QSAR study of novel acyl thiourea compounds containing gem-dimethylcyclopropane ring - Mei Huang; Min Huang; Xiu Wang; Wen-Gui Duan; Gui-Shan Lin; Fu-Hou Lei (Molecular Diversity, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

8- O - β -D-Glucopyranosyl-2-methylchromone, a new chromone glycoside from the Tibetan medicine plant of Swertia punicea Hemsl - Lin-Yun Mou; Min Wei; Hai-Yan Wu; Li-Jiao Hu; Jian-Long Li; Gan-Peng Li (Natural Product Research, 2022)

MAPK5 and MAPK10 overexpression influences strawberry fruit ripening, antioxidant capacity and resistance to Botrytis cinerea - Yunting Zhang; Yu Long; Yiting Liu; Min Yang; Liangxin Wang; Xiaoyang Liu; Yong Zhang; Qing Chen; Mengyao Li; Yuanxiu Lin; Haoru Tang; Ya Luo (Planta, 2022)

Genome survey sequencing of common vetch (Vicia sativa L.) and genetic diversity analysis of Chinese germplasm with genomic SSR markers - Lin Ma; Xiao Wang; Min Yan; Fang Liu; Shuxing Zhang; Xuemin Wang (Molecular Biology Reports, 2022)
Background Common vetch ( Vicia sativa L.) is an annual legume with excellent suitability in cold and dry regions. Despite its great applied potential, the genomic information regarding common vetch currently remains unavailable. Methods and results In the present study, the whole genome survey of common vetch was performed using the next-generation sequencing (NGS). A total of 79.84 Gbp high quality sequence data were obtained and assembled into 3,754,145 scaffolds with an N50 length of 3556 bp. According to the K-mer analyses, the genome size, heterozygosity rate and GC content of common vetch genome were estimated to be 1568 Mbp, 0.4345 and 35%, respectively. In addition, a total of 76,810 putative simple sequence repeats (SSRs) were identified. Among them, dinucleotide was the most abundant SSR type (44.94%), followed by Tri- (35.82%), Tetra- (13.22%), Penta- (4.47%) and Hexanucleotide (1.54%). Furthermore, a total of 58,175 SSR primer pairs were designed and ten of them were validated in Chinese common vetch. Further analysis showed that Chinese common vetch harbored high genetic diversity and could be clustered into two main subgroups. Conclusion This is the first report about the genome features of common vetch, and the information will help to design whole genome sequencing strategies. The newly identified SSRs in this study provide basic molecular markers for germplasm characterization, genetic diversity and QTL mapping studies for common vetch.

Parallel Metabolomic Profiling of Cerebrospinal Fluid, Plasma, and Spinal Cord to Identify Biomarkers for Spinal Cord Injury - Hua Yang; Pengwei Zhang; Min Xie; Jianxian Luo; Jing Zhang; Guowei Zhang; Yang Wang; Hongsheng Lin; Zhisheng Ji (Journal of Molecular Neuroscience, 2022)
Loss of physical and emotional health due to spinal cord injury (SCI) has been rapidly increasing worldwide. Effective evaluation of the severity of SCI is crucial to its prognosis. Herein, we constructed rat models of SCI with four different degrees of injury (sham group, light injury group, moderate injury group, and heavy injury group), using the surgical approach. Cerebrospinal fluid (CSF), plasma, and spinal cord were sampled at the sub-acute spinal cord (72 h post-injury) from each rat. The LC–MS-based metabolic profiling of these samples was performed according to a universal metabolome standard (UMS). The results demonstrated that 130, 104, and 128 metabolites were significantly altered within the CSF, plasma, and spinal cord samples, respectively. Among them, there were four differential metabolites, including uric acid, phosphorycholine, pyridoxine, and guanidoacetic acid, which were commonly identified within the CSF, plasma, and spinal cord samples. Further pathway analysis of these differential metabolites demonstrated a disturbance in the metabolism of glyoxylate and dicarboxylate and glycine, serine, and threonine which were associated with pathophysiologic consequence of spinal cord injury. In particular, phosphorycholine, pyridoxine, and guanidoacetic acid demonstrated a relationship with SCI severity. Thus, they could be utilized as potential metabolite biomarkers for SCI severity assessment.

The effects of immersive garden experience on the health care to elderly residents with mild-to-moderate cognitive impairment living in nursing homes after the COVID-19 pandemic - Chung-Heng Hsieh; Cheng-Min Chen; Ju-Yuan Yang; Yen-Ju Lin; Man-Li Liao; Ke-Hsin Chueh (Landscape and Ecological Engineering, 2022)

Precise orbit determination of the Haiyang 2C altimetry satellite using attitude modeling - Youcun Wang; Min Li; Kecai Jiang; Wenwen Li; Qile Zhao; Hailong Peng; Minseng Lin (GPS Solutions, 2022)

Halomonas populi sp. nov. isolated from Populus euphratica - Lin Xu; Jun-Jie Ying; Yuan-Chun Fang; Ran Zhang; Jia Hua; Min Wu; Bing-Nan Han; Cong Sun (Archives of Microbiology, 2022)

Streptomyces blattellae, a novel actinomycete isolated from the in vivo of a Blattella germanica - Gui-Min Liu; Lin-Lin Yuan; Li-Li Zhang; Hong Zeng (Antonie van Leeuwenhoek, 2022)

Mitogenomes provide new insights into the evolutionary history of Prodiamesinae (Diptera: Chironomidae) - Xiao‐Long Lin; Yan‐Min Zhao; Li‐Ping Yan; Wen‐Bin Liu; Wen‐Jun Bu; Xin‐Hua Wang; Chen‐Guang Zheng (Zoologica Scripta, 2022)
Evolutionary analysis of Prodiamesinae has long been impeded by lack of information, and its phylogenetic relationship with Orthocladiinae remains questionable. Here, ten complete mitochondrial genomes (mitogenomes) of Orthocladiinae sensu lato were newly sequenced, including three Prodiamesinae species and seven Orthocladiinae species. Coupled with published mitogenomes, a total of 12 mitogenomes of Orthocladiinae sensu lato were selected for a comparative mitogenomic analysis and phylogenetic reconstruction. Mitogenomes of Orthocladiinae sensu lato are conserved in structure, and all genes arrange the same gene order as the ancestral insect mitogenome. Nucleotide composition is highly biased, and the control region displayed the highest A + T content. All protein‐coding genes are under purifying selection, and the ATP8 evolves at the fastest rate. In addition, the mitogenomes of Orthocladiinae sensu lato are highly conserved, and they are practically useful for phylogenetic inference, suggesting a re‐classification of Orthocladiinae by sinking Prodiamesinae as a subgroup of Orthocladiinae.

Species Composition and Assemblages of Ichthyoplankton in Sansha Bay, Fujian Province, China - Yan Jiang; Bai-an Lin; Hao-yang He; Guang-mao Ding; Li-ting Yan; Ge Zhang; Min Liu; Lian-ming Zheng (Frontiers in Marine Science, 2021)
Sansha Bay (26.40−27.00°N, 119.50−120.20°E) is a typical semi-enclosed bay, located in northern Fujian Province, China, and adjacent to the East China Sea. The ichthyoplankton species composition and assemblage structure were investigated based on monthly sampling at 25 stations in April−September 2019, covering the important spring and summer spawning seasons in the region. Sampling was conducted in the first 3−5 days of the full moon or new moon phases using a standard plankton net through horizontal and vertical tows during daytime. In total, 25,819 ichthyoplankton samples were collected, of which 25,449 samples (i.e., 24,757 eggs and 692 larvae) were from horizontal tows. For horizontal tow samples, the ichthyoplankton were classified into 58 taxa in 15 orders and 23 families with a combination of external morphology and DNA barcoding analyses, from pelagic to demersal and benthic species. The dominant order was the Gobiiformes, including 23 species (39.7% of all species). The dominant taxa, in terms of relative abundance and frequency of occurrence, consisted of commercially important fishes, such as Setipinna tenuifilis (Valenciennes, 1848) (Engraulidae), Epinephelus akaara (Temminck and Schlegel, 1842) (Serraenidae), Collichthys lucidus (Richardson, 1844), Nibea albiflora (Richardson, 1846) (Sciaenidae), Acanthopagrus schlegelii (Bleeker, 1854), and Pagrus major (Temminck and Schlegel, 1843) (Sparidae), accounting for 78.9% of the horizontal tow samples. Low-valued and small-sized fishes, such as Stolephorus commersonnii Lacepède, 1803 (Engraulidae), Solea ovata Richardson, 1846 (Soleidae), Nuchequula nuchalis (Temminck and Schlegel, 1845), and Photopectoralis bindus (Valenciennes, 1835) (Leiognathidae), were also dominant species, accounting for 11.4% of the horizontal tow samples. The ichthyoplankton assemblage was categorized into five different temporal assemblages based on the cluster and nonmetric multidimensional scaling analysis, namely, April, May, June, July, and August−September (ANOSIM, Global R = 0.656, p < 0.01) with the highest density and richness of ichthyoplankton occurred in May. The spatial distribution pattern showed that the high density (ind./m 3 ) of ichthyoplankton occurred mainly in S12–S25 in Guanjingyang and along the Dongchong Peninsula coastline into Dongwuyang, while low density occurred mainly in S01–S11 in the northwest waters of Sandu Island (ANOVA, F = 8.270, p < 0.05). Temperature, salinity, and chlorophyll a were key factors structuring the ichthyoplankton assemblages in Sansha Bay. In addition, this study revealed the changes of the ichthyoplankton composition, density, and spatial distribution in Sansha Bay over the past three decades.

LncRNA-SNHG16 promotes proliferation and migration of acute myeloid leukemia cells via PTEN/PI3K/AKT axis through suppressing CELF2 protein - Min Shi; Ruili Yang; Jing Lin; Qi Wei; Lei Chen; Weifeng Gong; Yang Li; Xiaobo Guo (Journal of Biosciences, 2021)

Optimizing the Wheat Seeding Rate for Wide-Space Sowing to Improve Yield and Water and Nitrogen Utilization - Zhixin Wang; Shahbaz Khan; Min Sun; Aixia Ren; Wen Lin; Pengcheng Ding; Hafeez Noor; Shaobo Yu; Yu Feng; Qiang Wang; Zhiqiang Gao (International Journal of Plant Production, 2021)

Expression profiling of WRKY transcription factors in Spinach - Yaying Ma; Shuai Chen; Hongying Yu; Ruoyu Li; Zhicong Lin; Mingxing Cai; Min Tang; Xingtan Zhang; Ray Ming (Euphytica, 2021)

Selenium-Alleviated Testicular Toxicity by Modulating Inflammation, Heat Shock Response, and Autophagy Under Oxidative Stress in Lead-Treated Chickens - Size Wang; Lulu Hou; Min Wang; Rui Feng; Xu Lin; Shifeng Pan; Qian Zhao; He Huang (Biological Trace Element Research, 2021)

Three new ester glycosides with cytotoxic activity from the seeds of Caesalpinia sappan - Min Wang; Juan Tan; Jun Chen; Tian Xie; Liang-Mo Lin; Li-Li Zhong; Xing-Jun Cai; Qiong-Shi Wu (Natural Product Research, 2021)

Harmful algal bloom-forming dinoflagellate Prorocentrum donghaiense inhibits the growth and photosynthesis of seaweed Sargassum fusiformis embryos - Caixia Wang; Min Wang; Binbin Chen; Wenli Qin; Lidong Lin; Chuanjun Dai; Hengguo Yu; Renhui Li; Min Zhao; Zengling Ma (Journal of Oceanology and Limnology, 2021)

Pseudomonas nanhaiensis sp. nov., a lipase-producing bacterium isolated from deep-sea sediment of the South China Sea - Yu Pang; Yage Zhang; Mengru Chen; Wei Lu; Ming Chen; Yongliang Yan; Min Lin; Wei Zhang; Zhengfu Zhou (Antonie van Leeuwenhoek, 2021)

Population, Reproductive and Fishery Dynamics of Spotted Box Crab (Calappa philargius), a New Claw-Only Fishery Species, in the Southern Taiwan Strait, China - Bai-an Lin; Yan Jiang; Robert Boenish; Qing Xu; Min Liu (Frontiers in Marine Science, 2021)
The spotted box crab Calappa philargius (Calappidae) is an increasingly consumed species in China, mainly sourced from a claw-only fishery. Being a not well-characterized species in the literature, this study is warranted to inform sustainable management approaches. Here we report on the first in-depth overview on biology and fishery dynamics of C. philargius in the southern Taiwan Strait of China. Whole body crabs ( N = 1,009) were collected monthly from January to December 2019 from trawlers, operating in the southern Taiwan Strait; sample collection was absent from May to July because of the national fishing moratorium regulation. Sex ratio, growth pattern, size at maturity and fecundity were estimated. The overall male: female ratio was 1: 1.47, significantly differing from the 1: 1 ( p < 0.01); monthly sex ratio variations were also significant ( p < 0.01), suggesting possible seasonal sexual segregation. We found the carapace widths (CW) of males were significantly larger than those of females ( p < 0.01). Based on the occurrence and percentages of berried females, we identified twin spawning events in January–April and August–October with the overall peak occurring in February. Size at 50% female maturity was 11.47 cm CW. Female absolute fecundity was significantly related to CW via a power function relationship ( N = 14, p < 0.01). The estimated average claw yield was 36.28 ± 3.07% of the whole body weight ( N = 95), irrespective of sex and size ( p > 0.5). Capture and trade data of C. philargius using trawl and trap fishing gears were documented to characterize claw-only fishery dynamics for future research and sustainable use.

Master regulator NtrC controls the utilization of alternative nitrogen sources in Pseudomonas stutzeri A1501 - Zhimin Yang; Qin Li; Yongliang Yan; Xiubin Ke; Yueyue Han; Shaoyu Wu; Fanyang Lv; Yahui Shao; Shanshan Jiang; Min Lin; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2021)
Pseudomonas stutzeri A1501 is a model strain used to study associative nitrogen fixation, and it possesses the nitrogen regulatory NtrC protein in the core genome. Nitrogen sources represent one of the important factors affecting the efficiency of biological nitrogen fixation in the natural environment. However, the regulation of NtrC during nitrogen metabolism in P. stutzeri A1501 has not been clarified. In this work, a phenotypic analysis of the ntrC mutant characterized the roles of NtrC in nitrogen metabolism and the oxidative stress response of P. stutzeri A1501. To systematically identify NtrC-controlled gene expression, RNA-seq was performed to further analyse the gene expression differences between the wild-type strain and the ∆ ntrC mutant under nitrogen fixation conditions. A total of 1431 genes were found to be significantly altered by ntrC deletion, among which 147 associative genes had NtrC-binding sites, and the pathways for nitrogen fixation regulation, nitrogenous compound acquisition and catabolism and nitrate assimilation were discussed. Furthermore, the oxidative stress-related gene ( katB ), which was upregulated by ntrC deletion, was suggested to be a potential target gene of NtrC, thus highlighting the importance of NtrC in nitrogenase protection against oxygen damage. Based on these findings, we propose that NtrC is a high-ranking element in the regulatory network of P. stutzeri A1501 that controls a variety of nitrogen metabolic and oxidative stress responsive traits required for adaptation to complex rhizosphere environments.

Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1 - Guang-Tong Jiang; Lin Shao; Shuo Kong; Meng-Liu Zeng; Jing-Jing Cheng; Tao-Xiang Chen; Song Han; Jun Yin; Wan-Hong Liu; Xiao-Hua He; Yu-Min Liu; Lanzi Gongga; et al. (Neuroscience Bulletin, 2021)

Genome-Wide Identification and Expression Analysis of the Barrel Medic (Medicago truncatula) and Alfalfa (Medicago sativa L.) Basic Helix-Loop-Helix Transcription Factor Family Under Salt and Drought Stresses - Boniface Ndayambaza; Xiaoyu Jin; Xueyang Min; Xiaoshan Lin; Xiaofan Yin; Wenxian Liu (Journal of Plant Growth Regulation, 2021)

Sandaracinobacteroides hominis gen. nov., sp. nov., isolated from human skin - Ping-Hua Qu; Hai-Min Luo; Jun-Hui Feng; Song Li; Cha Chen; Lei Dong; Yu-Zhen Ming; Wen-Jun Li; Ying Lin (Archives of Microbiology, 2021)

Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson’s disease: a systematic review and meta-analysis - De-Qi Jiang; Qing-Min Zang; Li-Lin Jiang; Yan Wang; Ming-Xing Li; Jing-Yi Qiao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Research progress on the impact of flood discharge atomization on the ecological environment - Li Lin; Yi Li; Wei Zhang; Zhuo Huang; Duan Chen; Min Liu; John Crittenden (Natural Hazards, 2021)

Research on targeted land poverty alleviation patterns based on the precise identification of dominant factors of rural poverty: a case study of Siyang County, Jiangsu Province, China - Min Min; Chen Lin; Xuejun Duan; Zhifeng Jin; Luocheng Zhang (Environment, Development and Sustainability, 2021)
Poverty is a common problem faced by various social and economic forms. Eliminating poverty is a major issue of common concern and research all over the world. Land policies for poverty alleviation are an effective means of affecting land agriculture development, increasing the productivity of cultivated land, and promoting growth in farmers’ income and production. In recent years, it has played an important role in promoting poverty alleviation in poverty-stricken areas. However, the poverty alleviation needs of township units have not been precisely identified, and one-size-fits-all land policies are unable to effectively allocate poverty alleviation resources. Consequently, the actual efficiency of policies has been severely restricted, leading to regional differences in poverty alleviation. In response to this bottleneck, this study takes Siyang County in Jiangsu Province as a case study and adopts the geographical detector model to diagnose and identify the spatial differentiation characteristics and dominant factors of poverty and in various townships. The results can be summarised as ‘four dominant factors of poverty—four regional types of poverty townships—four targeted land poverty alleviation patterns’. Detailed results are as follows: the dominant factors affecting differentiation of rural poverty in Siyang County are labour, technology, land resources, and financial support. The various townships of the county were thus classified into four types according to the main factor affecting poverty: labour-constrained, land-constrained, capital-constrained, and technique-constrained, and proposed four targeted land poverty alleviation patterns for the different constraint types and then to improve the effectiveness of land development policies to successfully achieve precise poverty alleviation and reinforce strategies revitalising rural communities.

Neuroanatomical correlates of self-awareness of highly practiced visuomotor skills - Junjun Li; Zhenglong Lin; Ran Tao; Min Xu; Shihong Kong; Hong-Yan Bi; Yang Yang (Brain Structure and Function, 2021)

Geographic modeling and simulation systems for geographic research in the new era: Some thoughts on their development and construction - Min Chen; Guonian Lv; Chenghu Zhou; Hui Lin; Zaiyang Ma; Songshan Yue; Yongning Wen; Fengyuan Zhang; Jin Wang; Zhiyi Zhu; Kai Xu; Yuanqing He (Science China Earth Sciences, 2021)
Regionality, comprehensiveness, and complexity are regarded as the basic characteristics of geography. The exploration of their core connotations is an essential way to achieve breakthroughs in geography in the new era. This paper focuses on the important method in geographic research: Geographic modeling and simulation. First, we clarify the research requirements of the said three characteristics of geography and its potential to address geo-problems in the new era. Then, the supporting capabilities of the existing geographic modeling and simulation systems for geographic research are summarized from three perspectives: Model resources, modeling processes, and operational architecture. Finally, we discern avenues for future research of geographic modeling and simulation systems for the study of regional, comprehensive and complex characteristics of geography. Based on these analyses, we propose implementation architecture of geographic modeling and simulation systems and discuss the module composition and functional realization, which could provide theoretical and technical support for geographic modeling and simulation systems to better serve the development of geography in the new era.

The relationship between anthocyanin accumulation and photoprotection in young leaves of two dominant tree species in subtropical forests in different seasons - Zheng-Chao Yu; Wei Lin; Xiao-Ting Zheng; Wah Soon Chow; Yan-Na Luo; Min-Ling Cai; Chang-Lian Peng (Photosynthesis Research, 2021)

The major photoprotective role of anthocyanins in leaves of Arabidopsis thaliana under long-term high light treatment: antioxidant or light attenuator? - Xiao-Ting Zheng; Zheng-Chao Yu; Jun-Wei Tang; Min-Ling Cai; Yi-Lin Chen; Cheng-Wei Yang; Wah Soon Chow; Chang-Lian Peng (Photosynthesis Research, 2021)

Photosynthetic compensation of non-leaf organ stems of the invasive species Sphagneticola trilobata (L.) Pruski at low temperature - Min-ling Cai; Wen-qiao Ding; Jun-jie Zhai; Xiao-ting Zheng; Zheng-chao Yu; Qi-lei Zhang; Xiao-hua Lin; Wah Soon Chow; Chang-lian Peng (Photosynthesis Research, 2021)

Hidden in plain sight: a molecular field survey of three wheat leaf blotch fungal diseases in North-Western Europe shows co-infection is widespread - Annemarie Fejer Justesen; Beatrice Corsi; Andrea Ficke; Lorenz Hartl; Sarah Holdgate; Lise Nistrup Jørgensen; Morten Lillemo; Min Lin; Ian J. Mackay; Volker Mohler; Melanie Stadlmeier; Kar-Chun Tan; et al. (European Journal of Plant Pathology, 2021)
Wheat ( Triticum aestivum L.) yields are commonly affected by foliar infection by fungal pathogens. Of these, three wheat leaf blotch fungal diseases, septoria nodorum blotch (SNB), tan spot (TS) and septoria tritici blotch (STB), caused by Parastagonospora nodorum ( Pn ), Pyrenophora tritici-repentis ( Ptr ) and Zymoseptoria tritici ( Zt ), respectively, induce major yield losses. Infection results in necrotic areas on the leaf, and it is often difficult to determine the underlying causative pathogen from visible symptoms alone, especially in mixed infections. Here, a regional survey of 330 wheat samples collected across three seasons (years 2015–2017) from four north-west European countries was undertaken. Using quantitative polymerase chain reaction (qPCR) assays specific for each pathogen, as well as disease assessment of leaf materials, distinct regional differences were identified. Two-thirds (65%) of all samples harbored at least two of the three pathogens. Norway had high SNB abundance, but also showed mixed infections of SNB, TS and STB. In Germany, TS was prevalent, with STB also common. Danish samples commonly possessed all three pathogens, with STB prevalent, followed by TS and SNB. The UK had a major prevalence of STB with minimal occurrence of TS and SNB. Across all samples, qPCR identified Zt , Pn and Ptr in 90%, 54% and 57% of samples, respectively. For each pathogen, average disease levels via visual assessment showed modest positive correlation with fungal DNA concentrations (R 2 = 0.13–0.32). Overall, our study highlights that the occurrence of mixed infection is common and widespread, with important implications for wheat disease management and breeding strategies.

Recycle of synthetic calcium fluoride and waste sulfuric acid to produce electronic grade hydrofluoric acid - Min-Fa Lin; Jhong-Lin Wu; Ken-Lin Chang; Wen-Jhy Lee; Chih-Ping Chang; Yung-Chang Lin; Po-Han Chen (Environmental Science and Pollution Research, 2021)

Three-Dimensional Mantle Flow and Temperature Structure Beneath the Shatsky Rise Ridge-Ridge-Ridge Triple Junction - Jinchang Zhang; Zhiyuan Zhou; Min Ding; Jian Lin (Journal of Ocean University of China, 2021)

RSF1 requires CEBP/β and hSNF2H to promote IL-1β-mediated angiogenesis: the clinical and therapeutic relevance of RSF1 overexpression and amplification in myxofibrosarcomas - Chien-Feng Li; Ti-Chen Chan; Cheng-I. Wang; Fu-Min Fang; Po-Chun Lin; Shih-Chen Yu; Hsuan-Ying Huang (Angiogenesis, 2021)

A new ent -kaurane diterpene from Isodon henryi - Xue Jiang; Ling-Xia Zhang; Qing-Mei Feng; Hong Wu; Ya-Lin Liu; De-Qin Wang; Li-Ping Dai; Zhi-Min Wang (Natural Product Research, 2021)

Phytoavailability, translocation and soil thresholds derivation of cadmium for food safety through soil-wheat (Triticum aestivum L.) system - Min Lu; Xuerui Cao; Qiang Lin; Bilal Hussain; Ying Feng; Zhenli He; Kyong Ju Kang; Xiaoe Yang (Environmental Science and Pollution Research, 2021)

Present in-situ stress distribution characteristics of strike-slip in SH Oilfield, Tarim Basin - Teng Zhao; Wenge Hu; Rui Zhao; Min Yang; Qiang Wang; Huixi Lin; Zhixing Ru; Dian Bao; Fei Cao (Arabian Journal of Geosciences, 2021)

Cysteiniphilum marinum sp. nov., isolated from coastal seawater - Hai-Min Luo; Jun-Hui Feng; Liang-Hui Li; Meng-Meng Li; Ru-Qin Liu; Fu Chen; Ying Lin; Wen-Jun Li; Ping-Hua Qu; Min Xiao (Antonie van Leeuwenhoek, 2021)

Relating leaf traits to seedling performance in a tropical forest: building a hierarchical functional framework - María Natalia Umaña; Nathan G. Swenson; Philippe Marchand; Min Cao; Luxiang Lin; Caicai Zhang (Ecology, 2021)
Trait‐based approaches have been extensively used in community ecology to provide a mechanistic understanding of the drivers of community assembly. However, a foundational assumption of the trait framework, traits relate to performance, has been mainly examined through univariate relationships that simplify the complex phenotypic integration of organisms. We evaluate a conceptual framework in which traits are organized hierarchically combining trait information at the individual‐ and species‐level from biomass allocation and organ‐level traits. We focus on photosynthetic traits and predict that the positive effects of increasing plant leaf mass on growth depend on species‐level leaf traits. We modeled growth data on more than 1,500 seedlings from 97 seedling species from a tropical forest in China. We found that seedling growth increases with allocation to leaves (high leaf area ratio and leaf mass fraction) and this effect is accentuated for species with high specific leaf area and leaf area. Also, we found that light has a significant effect on growth, and this effect is additive with leaf allocation traits. Our work offers an approach to gain further understanding of the effects of traits on the whole plant‐level growth via a hierarchical framework including organ‐level and biomass allocation traits at species and individual levels.

Secondary Structural Transformation of Bovine Lactoferricin Affects Its Antibacterial Activity - Jie Pei; Lin Xiong; Pengjia Bao; Min Chu; Ping Yan; Xian Guo (Probiotics and Antimicrobial Proteins, 2021)

Traits, strategies, and niches of liana species in a tropical seasonal rainforest - Qi Liu; Frank J. Sterck; Jiao-Lin Zhang; Arne Scheire; Evelien Konings; Min Cao; Li-Qing Sha; Lourens Poorter (Oecologia, 2021)
Plant functional traits and strategies hold the promise to explain species distribution, but few studies have linked multiple traits to multiple niche dimensions (i.e., light, water, and nutrients). Here, we analyzed for 29 liana species in a Chinese tropical seasonal rainforest how: (1) trait associations and trade-offs lead to different plant strategies; and (2) how these traits shape species’ niche dimensions. Eighteen functional traits related to light, water, and nutrient use were measured and species niche dimensions were quantified using species distribution in a 20-ha plot combined with data on canopy gaps, topographic water availability, and soil nutrients. We found a tissue toughness spectrum ranging from soft to hard tissues along which species also varied from acquisitive to conservative water use, and a resource acquisition spectrum ranging from low to high light capture and nutrient use. Intriguingly, each spectrum partly reflected the conservative–acquisitive paradigm, but at the same time, the tissue toughness and the resource acquisition spectrum were uncoupled. Resource niche dimensions were better predicted by individual traits than by multivariate plant strategies. This suggests that trait components that underlie multivariate strategy axes, rather than the plant strategies themselves determine species distributions. Different traits were important for different niche dimensions. In conclusion, plant functional traits and strategies can indeed explain species distributions, but not in a simple and straight forward way. Although the identification of global plant strategies has significantly advanced the field, this research shows that global, multivariate generalizations are difficult to translate to local conditions, as different components of these strategies are important under different local conditions.

Experimental Research on Adsorption Kinetic Characteristics of CH4, CO2, and N2 in Coal from Junggar Basin, China, at Different Temperatures - Wanjie Sun; Haifei Lin; Shugang Li; Xiangguo Kong; Hang Long; Min Yan; Yang Bai; Jiamin Tian (Natural Resources Research, 2021)

Safety and efficacy of new oral anticoagulants compared to those of warfarin in AF patients with cancer: a meta-analysis of randomized clinical trials and observational studies - Yueming Chen; Min Mao; Jing Chang; Jing Yan; Tiantian Yang; Yang Liu; Meng Luo; Yuhao Hu; Qi Yang; Lin Zhou; Kanghua Ma (European Journal of Clinical Pharmacology, 2021)

Kelp aquaculture in China: a retrospective and future prospects - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
Globally, China has the largest scale of kelp cultivation and production operations. However, its kelp aquaculture industry is suffering from declining germplasm diversity, degradation of agronomic traits, the presence of polluted environments, changing ocean conditions and increasing anthropological interference. This review covers two of the most commercially important kelp species in China, viz. Saccharina japonica and Undaria pinnatifida . It summarizes the history of their cultivation, production, economic and ecological benefits, their breeding programmes (e.g. inter‐ and intra‐specific hybridization and marker‐assisted selection) and efforts towards population genetic diversity and conservation. The article focuses on three significant challenges, for example genetic cross‐contamination between the wild and farmed kelp populations, ocean warming and ocean acidification. Accordingly, we outline the steps required to provide several intervention measures, for example (i) collection and preservation of wild and cultivated kelp germplasm; (ii) selection of suitable cultivation sites under changing environmental conditions; (iii) developing stress‐resistant cultivars; and finally, (iv) adoption of innovative cultivation models. The review concludes with genome‐based, designs for molecular breeding and calls for the establishment of an East Asian Kelp Consortium (EAKC). Collectively, the Chinese kelp industry could provide beneficial goods and services, for example bioenergy to fine chemicals and environmental benefits, such as carbon capture, pH amelioration and provision of habitat for many other marine species of commercial value. The strategies proposed in this article thus have the potential to not only improve but also reinvigorate the kelp industry in China and nearby Japan and Korea, in the context of both environmental health and economic benefits.

Cover Image - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
The cover image is based on the Review Article Kelp aquaculture in China: A retrospective and future prospects by Zi‐Min Hu et al., https://doi.org/10.1111/raq.12524 . image

Provenance of the Late Cretaceous sediments in Jiaolai Basin, Eastern China, and its tectonic implications - Bo Zhang; Shaofeng Liu; Chengfa Lin; Yu Wang; Zhehan Wang; Min Fang; Wenjie Shen (International Geology Review, 2021)

Identification of eight QTL controlling multiple yield components in a German multi-parental wheat population, including Rht24, WAPO-A1, WAPO-B1 and genetic loci on chromosomes 5A and 6A - Beatrice Corsi; Lia Obinu; Camila M. Zanella; Saverio Cutrupi; Rob Day; Manuel Geyer; Morten Lillemo; Min Lin; Lorenzo Mazza; Lawrence Percival-Alwyn; Melanie Stadlmeier; Volker Mohler; et al. (Theoretical and Applied Genetics, 2021)
Key message Quantitative trait locus (QTL) mapping of 15 yield component traits in a German multi-founder population identified eight QTL each controlling ≥2 phenotypes, including the genetic loci Rht24 , WAPO-A1 and WAPO-B1 . Abstract Grain yield in wheat ( Triticum aestivum L.) is a polygenic trait representing the culmination of many developmental processes and their interactions with the environment. Toward maintaining genetic gains in yield potential, ‘reductionist approaches’ are commonly undertaken by which the genetic control of yield components, that collectively determine yield, are established. Here we use an eight-founder German multi-parental wheat population to investigate the genetic control and phenotypic trade-offs between 15 yield components. Increased grains per ear was significantly positively correlated with the number of fertile spikelets per ear and negatively correlated with the number of infertile spikelets. However, as increased grain number and fertile spikelet number per ear were significantly negatively correlated with thousand grain weight, sink strength limitations were evident. Genetic mapping identified 34 replicated quantitative trait loci (QTL) at two or more test environments, of which 24 resolved into eight loci each controlling two or more traits—termed here ‘multi-trait QTL’ (MT-QTL). These included MT-QTL associated with previously cloned genes controlling semi-dwarf plant stature, and with the genetic locus Reduced height 24 ( Rht24 ) that further modulates plant height. Additionally, MT-QTL controlling spikelet number traits were located to chromosome 7A encompassing the gene WHEAT ORTHOLOG OF APO1 ( WAPO-A1 ), and to its homoeologous location on chromosome 7B containing WAPO-B1 . The genetic loci identified in this study, particularly those that potentially control multiple yield components, provide future opportunities for the targeted investigation of their underlying genes, gene networks and phenotypic trade-offs, in order to underpin further genetic gains in yield.

Development and evaluation of a serological test for diagnosis of COVID-19 with selected recombinant spike proteins - Pingping Zhang; Qi Gao; Tang Wang; Yuehua Ke; Fei Mo; Ruizhong Jia; Wanbing Liu; Lei Liu; Shangen Zheng; Yuzhen Liu; Luping Li; Yao Wang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Identification of miRNA targets in eggplant in response to Verticillium dahliae by degradome sequencing - Ting Li; Nianjiao Tao; Yuanmi Lin; Min Chen; Dongli Jiao; Chunmei Xue; Wenjiao Zhu; Qing Yang (European Journal of Plant Pathology, 2021)

Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling - Size Li; Yiqun Yu; Xiaolan Bian; Li Yao; Min Li; Yan-Ru Lou; Jing Yuan; Hai-shu Lin; Lucy Liu; Bing Han; Xiaoqiang Xiang (Archives of Toxicology, 2021)

Cabbage defense response provoked by Trichoderma Th-LAAO - Chia-Min Liu; Shu-Ying Liu; Chuan-Kai Liao; Chaur-Tsuen Lo; Kuo-Chih Lin; Kou-Cheng Peng (Archives of Microbiology, 2021)

Variations in melt supply along an orthogonal supersegment of the Southwest Indian Ridge (16°–25°E) - Caicai Zha; Jian Lin; Zhiyuan Zhou; Xubo Zhang; Min Xu; Fan Zhang (Acta Oceanologica Sinica, 2021)

Mortality burden caused by diurnal temperature range: a nationwide time-series study in 364 Chinese locations - Min Cai; Jianxiong Hu; Chunliang Zhou; Zhulin Hou; Yanjun Xu; Maigeng Zhou; Yize Xiao; Biao Huang; Xiaojun Xu; Lifeng Lin; Tao Liu; Jianpeng Xiao; et al. (Stochastic Environmental Research and Risk Assessment, 2021)

Catalyst-free visible-light induced synthesis of nitrogen- and oxygen-containing heterocycles from 1,3-diketones - Lu Chen; Zhenyuan lin; Xuefang Zhang; Leshi Tan; Min Zhang; Yibiao Li (Environmental Chemistry Letters, 2021)

Experimental and numerical study on the fragmentation mechanism of a single calcareous sand particle under normal compression - Du-min Kuang; Zhi-lin Long; Rui-qi Guo; Tao Zhao; Kai Wu (Bulletin of Engineering Geology and the Environment, 2021)

Corrosion Mechanism of 5083 Aluminum Alloy in Seawater Containing Phosphate - Jiaming Wang; Haodong Yang; Min Du; Jian Hou; Wenshan Peng; Cunguo Lin (Journal of Ocean University of China, 2021)

Alternation of soil bacterial and fungal communities by tomato–rice rotation in Hainan Island in Southeast of China - Xiang Ma; Minglun Du; Peng Liu; Yanqiong Tang; Hong Li; Qianhua Yuan; Yunze Ruan; Lei Meng; Jiachao Zhang; Min Lin; Zhu Liu (Archives of Microbiology, 2021)

New secondary metabolite with cytotoxicity from spawning soft coral Asterospicularia laurae in Taiwan - Jui-Hsin Su; Chih-I Liu; Mei-Chin Lu; Chi-I Chang; Min-Ying Hsieh; Yu-Chi Lin; Chang-Feng Dai; Ya-Han Zhang; Zheng-Yu Lin; Yun-Sheng Lin (Natural Product Research, 2021)

Effect of replacing inorganic trace minerals at lower organic levels on growth performance, blood parameters, antioxidant status, immune indexes, and fecal mineral excretion in weaned piglets - Wen-Fei Zhang; Min Tian; Jun-Shuai Song; Fang Chen; Gang Lin; Shi-Hai Zhang; Wu-Tai Guan (Tropical Animal Health and Production, 2021)

Biopharmaceutics Applications of Physiologically Based Pharmacokinetic Absorption Modeling and Simulation in Regulatory Submissions to the U.S. Food and Drug Administration for New Drugs - Fang Wu; Heta Shah; Min Li; Peng Duan; Ping Zhao; Sandra Suarez; Kimberly Raines; Yang Zhao; Meng Wang; Ho-pi Lin; John Duan; Lawrence Yu; et al. (The AAPS Journal, 2021)

First Detection and Molecular Identification of Entamoeba in Yaks from China - Mei Ren; Fan Yang; Jing-min Gou; Pin-xue Wang; Min Zou; Xiao-hong Zhong; Qing Lin (Acta Parasitologica, 2021)

Direct Calculation Method for the Analysis of Non-linear Behavior of Ground-Support Interaction of a Circular Tunnel Using Convergence Confinement Approach - Yu-Lin Lee; Wen-Kuei Hsu; Chi-Min Lee; Yi-Xian Xin; Bo-Yu Zhou (Geotechnical and Geological Engineering, 2021)

Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients - Hou-wei Du; Jun-nian Chen; Xiao-bin Pan; Xiao-ling Chen; Yixian-Zhang; Shuang-fang Fang; Xiao-qing Li; Pin-cang Xia; Lei Gao; Hai-long Lin; Li-min Chen; Nan Liu (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Hydrochemical composition, distribution, and sources of typical organic pollutants and metals in Lake Bangong Co, Tibet - Li Lin; Lei Dong; Zhen Wang; Chao Li; Min Liu; Qingyun Li; John C. Crittenden (Environmental Science and Pollution Research, 2021)

Seasonal analysis of artificial oyster reef ecosystems: implications for sustainable fisheries management - Min Xu; Xin yuan Yang; Xiao jing Song; Kai da Xu; Lin lin Yang (Aquaculture International, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Identification and cross-validation of genetic loci conferring resistance to Septoria nodorum blotch using a German multi-founder winter wheat population - Min Lin; Melanie Stadlmeier; Volker Mohler; Kar-Chun Tan; Andrea Ficke; James Cockram; Morten Lillemo (Theoretical and Applied Genetics, 2021)
Key message We identified allelic variation at two major loci, QSnb.nmbu-2A.1 and QSnb.nmbu-5A.1 , showing consistent and additive effects on SNB field resistance. Validation of QSnb.nmbu-2A.1 across genetic backgrounds further highlights its usefulness for marker-assisted selection. Abstract Septoria nodorum blotch (SNB) is a disease of wheat ( Triticum aestivum and T. durum ) caused by the necrotrophic fungal pathogen Parastagonospora nodorum . SNB resistance is a typical quantitative trait, controlled by multiple quantitative trait loci (QTL) of minor effect. To achieve increased plant resistance, selection for resistance alleles and/or selection against susceptibility alleles must be undertaken. Here, we performed genetic analysis of SNB resistance using an eight-founder German Multiparent Advanced Generation Inter-Cross (MAGIC) population, termed BMWpop. Field trials and greenhouse testing were conducted over three seasons in Norway, with genetic analysis identifying ten SNB resistance QTL. Of these, two QTL were identified over two seasons: QSnb.nmbu-2A.1 on chromosome 2A and QSnb.nmbu-5A.1 on chromosome 5A. The chromosome 2A BMWpop QTL co-located with a robust SNB resistance QTL recently identified in an independent eight-founder MAGIC population constructed using varieties released in the United Kingdom (UK). The validation of this SNB resistance QTL in two independent multi-founder mapping populations, regardless of the differences in genetic background and agricultural environment, highlights the value of this locus in SNB resistance breeding. The second robust QTL identified in the BMWpop, QSnb.nmbu-5A.1, was not identified in the UK MAGIC population. Combining resistance alleles at both loci resulted in additive effects on SNB resistance. Therefore, using marker assisted selection to combine resistance alleles is a promising strategy for improving SNB resistance in wheat breeding. Indeed, the multi-locus haplotypes determined in this study provide markers for efficient tracking of these beneficial alleles in future wheat genetics and breeding activities.

Identification and expression analysis of caffeoyl-coenzyme A O-methyltransferase family genes related to lignin biosynthesis in tea plant (Camellia sinensis) - Shi-Jia Lin; Ya-Zhuo Yang; Rui-Min Teng; Hao Liu; Hui Li; Jing Zhuang (Protoplasma, 2021)

Effects of shading on lignin biosynthesis in the leaf of tea plant (Camellia sinensis (L.) O. Kuntze) - Rui-Min Teng; Yong-Xin Wang; Hui Li; Shi-Jia Lin; Hao Liu; Jing Zhuang (Molecular Genetics and Genomics, 2021)

A plant virus mediates interspecific competition between its insect vectors in Capsicuum annuum - Yong Chen; Xue Zheng; Hui Wei; Yong-Dui Chen; Kuan-Yu Zheng; Ye Mu; Xing-Yue Zhao; Li-Hua Zhao; Yu-Lin Gao; Li-Min Zheng; Jie Zhang (Journal of Pest Science, 2021)

Geographical and interspecific variation in susceptibility of three common thrips species to the insecticide, spinetoram - Yong-Fu Gao; Ya-Jun Gong; Li-Jun Cao; Jin-Cui Chen; Yu-Lin Gao; Majid Mirab-balou; Min Chen; Ary A. Hoffmann; Shu-Jun Wei (Journal of Pest Science, 2021)

Concurrent increases in post-pacing action potential duration and contractility predict occurrence of ventricular arrhythmia - Chih-Min Liu; Feng-Zhi Lin; Yao-Chang Chen; Yung-Kuo Lin; Yen-Yu Lu; Cheng-I Wu; Satoshi Higa; Shih-Ann Chen; Yi-Jen Chen (Pflügers Archiv - European Journal of Physiology, 2020)

miR-4417 suppresses keloid fibrosis growth by inhibiting CyclinD1 - Pei Liu; Yaotian Hu; Lin Xia; Min Du; Zhensheng Hu (Journal of Biosciences, 2020)

Hepato-protective effect of fucoidan extracted from acid-processed Sargassum fusiformis in ethanol-treated Chang liver cells and in a zebrafish model - Yu-Lin Dai; Yun-Fei Jiang; Yu-Hang Nie; Yu-An Lu; Min-Cheol Kang; You-Jin Jeon (Journal of Applied Phycology, 2020)

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages - Chun-Ying Qiao; Ying Li; Yue Shang; Min Jiang; Jian Liu; Zi-Ying Zhan; Huan Ye; Yong-Ce Lin; Jing-Ya Jiao; Rong-Hui Sun; Zhi-Hong Zhang; Mei-Hua Piao; et al. (Inflammopharmacology, 2020)

Seasonal succession of phytoplankton in two temperate artificial lakes with different water sources - Jing Wei; Min Wang; Chongtai Chen; Haiming Wu; Li Lin; Ming Li (Environmental Science and Pollution Research, 2020)

Endoplasmic reticulum‐associated degradation mediated by MoHrd1 and MoDer1 is pivotal for appressorium development and pathogenicity of Magnaporthe oryzae - Wei Tang; Haolang Jiang; Osakina Aron; Min Wang; Xueyu Wang; Jiangfeng Chen; Birong Lin; Xuehang Chen; Qiaojia Zheng; Xiuqin Gao; Dou He; Airong Wang; et al. (Environmental Microbiology, 2020)
Summary Most secretory proteins are folded and modified in the endoplasmic reticulum (ER); however, protein folding is error‐prone, resulting in toxic protein aggregation and cause ER stress. Irreversibly misfolded proteins are subjected to ER‐associated degradation (ERAD), modified by ubiquitination, and degraded by the 26S proteasome. The yeast ERAD ubiquitin ligase Hrd1p and multispanning membrane protein Der1p are involved in ubiquitination and transportation of the folding‐defective proteins. Here, we performed functional characterization of MoHrd1 and MoDer1 and revealed that both of them are localized to the ER and are pivotal for ERAD substrate degradation and the ER stress response. MoHrd1 and MoDer1 are involved in hyphal growth, asexual reproduction, infection‐related morphogenesis, protein secretion and pathogenicity of M. oryzae . Importantly, MoHrd1 and MoDer1 mediated conidial autophagic cell death and subsequent septin ring assembly at the appressorium pore, leading to abnormal appressorium development and loss of pathogenicity. In addition, deletion of MoHrd1 and MoDer1 activated the basal unfolded protein response (UPR) and autophagy, suggesting that crosstalk between ERAD and two other closely related mechanisms in ER quality control system (UPR and autophagy) governs the ER stress response. Our study indicates the importance of ERAD function in fungal development and pathogenesis of M. oryzae .

Linking Ecology to Genetics to Better Understand Adaptation and Evolution: A Review in Marine Macrophytes - Zi-Min Hu; Kai-Le Zhong; Florian Weinberger; De-Lin Duan; Stefano G. A. Draisma; Ester A. Serrão (Frontiers in Marine Science, 2020)

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death - Mengyu Liu; Dexin Sui; Thomas Dexheimer; Stacy Hovde; Xiexiong Deng; Kuang-Wei Wang; Hsin Lian Lin; Hsiao-Tien Chien; Hye Kyong Kweon; Nora Sheen Kuo; Christopher A. Ayoub; Daniela Jimenez-Harrison; et al. (Molecular Neurobiology, 2020)

Intention to adopt bicycle-sharing in China: introducing environmental concern into the theory of planned behavior model - Min Zhu; Xianfeng Hu; Zhengzheng Lin; Jun Li; Shanyong Wang; Chengyuan Wang (Environmental Science and Pollution Research, 2020)

A Comparative Study of Associated Microbiota Between Pig Farm and Pig Slaughterhouse in Guangdong, China - Jian-Yong Wu; Yan-Shan Zhu; Cheng Guo; Yao Xia; Zhong-Min Guo; Qian-Lin Li; Jia-Hai Lu (Current Microbiology, 2020)

Spatial and temporal distributions of bisphenol analogues in water and sediment from the Lanzhou section of the Yellow River, China - Xia Zhao; Hang Zhang; Zhong-lin Chen; Xiao-chun Wang; Ji-min Shen (Arabian Journal of Geosciences, 2020)

New sorbicillinoid derivatives with GLP-1R and eEF2K affinities from a sponge-derived fungus Penicillium chrysogenum 581F1 - Min-Jia Cao; Tao Zhu; Jing-Tang Liu; Liang Ouyang; Fan Yang; Hou-Wen Lin (Natural Product Research, 2020)

Impact of prophylactic/preemptive donor lymphocyte infusion and intensified conditioning for relapsed/refractory leukemia: a real-world study - Yu Wang; Qi-Fa Liu; De-Pei Wu; Jing-Bo Wang; Xi Zhang; Heng-Xiang Wang; Feng Gao; Shun-Qing Wang; Zi-Min Sun; Jian Ouyang; Kai-Lin Xu; Su-Jun Gao; et al. (Science China Life Sciences, 2020)

A Novel Assessment of Baroreflex Activity Through the Similarity of Ternary Codes of Oscillations Between Arterial Blood Pressure and R–R Intervals - Po-Wei Chen; Chun-Keng Lin; Wei-Min Liu; Yu-Chen Chen; Sheng-Tzung Tsai; An-Bang Liu (Journal of Medical and Biological Engineering, 2020)

Tectochrysin increases stress resistance and extends the lifespan of Caenorhabditis elegans via FOXO/DAF-16 - Min Lu; Lin Tan; Xiao-Gang Zhou; Zhong-Lin Yang; Qing Zhu; Jian-Ning Chen; Huai-Rong Luo; Gui-Sheng Wu (Biogerontology, 2020)

Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study - Ming-Cheng Wang; Ahmad Imran Zaydi; Wei-Hung Lin; Jin-Seng Lin; Min-Tze Liong; Jiunn-Jong Wu (Probiotics and Antimicrobial Proteins, 2020)

Impact of Maternal Separation on Dopamine System and its Association with Parkinson's Disease - Kai-jie He; Yu-ting Zhang; Shi-zhuang Wei; Shu-min Jiang; Lin Xu; Chao Ren; Fen Wang (NeuroMolecular Medicine, 2020)

Genome-wide identification of the Sec-dependent secretory protease genes in Erwinia amylovora and analysis of their expression during infection of immature pear fruit - Wang-bin Zhang; Hai-lin Yan; Zong-cai Zhu; Chao Zhang; Pei-xiu Du; Wen-jun Zhao; Wei-min Li (Journal of Zhejiang University-SCIENCE B, 2020)

Gastrointestinal involvement of COVID-19 and potential faecal transmission of SARS-CoV-2 - Min Song; Zong-lin Li; Ye-jiang Zhou; Gang Tian; Ting Ye; Zhang-rui Zeng; Jian Deng; Hong Wan; Qing Li; Jin-bo Liu (Journal of Zhejiang University-SCIENCE B, 2020)

The effect of fumigation with microencapsulated allyl isothiocyanate in a gas-barrier bag against Solenopsis invicta (Hymenoptera: Formicidae) - Yoshiaki Hashimoto; Hironori Sakamoto; Hiromi Asai; Masamitsu Yasoshima; Hui-Min Lin; Koichi Goka (Applied Entomology and Zoology, 2020)
Red imported fire ants, Solenopsis invicta Buren (Hymenoptera: Formicidae), which are among the most harmful alien ants, were first detected in Japan in a shipping container from China in May 2017, and continue to enter Japan via this trade pathway. Fumigation is one of the most effective ways to eliminate S. invicta from goods transported in containers. The present study is the first to evaluate the effect of fumigation with allyl isothiocyanate (AITC) against S. invicta . Fumigation using microencapsulated AITC pellets in a gas-barrier bag for 24 h completely killed S. invicta . Furthermore, our fumigation system was able to maintain a high concentration of AITC vapor for at least 13 days. AITC, a naturally occurring compound in wasabi [ Eutrema japonicum (Miq.) Koidz], has been demonstrated to be safe for humans and the environment, but its use as a fumigant is limited by its strong volatility and pungency. However, its encapsulation solves this problem by allowing controlled vapor release. Thus, the use of microencapsulated AITC in combination with a gas-barrier bag has considerable potential to provide an effective and easy-to-use protocol for fumigation of S. invicta .

A new 5α,8α-epidioxysterol with immunosuppressive activity from the South China Sea soft coral Sinularia sp. - Min Yang; Lin-Fu Liang; Heng Li; Wei Tang; Yue-Wei Guo (Natural Product Research, 2020)

Three new phenylacetamide glycosides from Dracocephalum tanguticum Maxim and their anti-hyperglycemic activity - En-Guang Ma; Hai-Yan Wu; Li-Jiao Hu; Min Wei; Lin-Yun Mou; Gan-Peng Li (Natural Product Research, 2020)

Drought-tolerant plant growth-promoting rhizobacteria isolated from jujube (Ziziphus jujuba) and their potential to enhance drought tolerance - Min Zhang; Lin Yang; Ruqian Hao; Xiaoxiong Bai; Ying Wang; Xuan Yu (Plant and Soil, 2020)

Structure Elucidation and Mechanistic Study of a New Dimeric Degradant in Ropinirole Hydrochloride Extended-Release Tablets - Zijian Kuang; Tianpei Huang; Dan Li; Danna Zhao; Jianyang Jin; Jinsheng Lin; Wenquan Zhu; Wenbin Chen; Min Li; Weiyang Shen (Pharmaceutical Research, 2020)

EGF neutralization antibodies attenuate liver fibrosis by inhibiting myofibroblast proliferation in bile duct ligation mice - Hufeng Xu; Lin Liu; Min Cong; Tianhui Liu; Shujie Sun; Hong Ma; Hong You; Jidong Jia; Ping Wang (Histochemistry and Cell Biology, 2020)

Protective effects of extracts from six local strains of Pyropia yezoensis against oxidative damage in vitro and in zebrafish model - Yu-Lin Dai; Gwang Hoon Kim; Min-Cheol Kang; You-Jin Jeon (Algae, 2020)

MtDNA-Based Phylogeography of the Red Alga Agarophyton vermiculophyllum (Gigartinales, Rhodophyta) in the Native Northwest Pacific - Kai-Le Zhong; Xiao-Han Song; Han-Gil Choi; Shimada Satoshi; Florian Weinberger; Stefano G. A. Draisma; De-Lin Duan; Zi-Min Hu (Frontiers in Marine Science, 2020)

The occurrence and spatial distribution of phthalate esters (PAEs) in the Lanzhou section of the Yellow River - Xia Zhao; Ji-min Shen; Hang Zhang; Xiang Li; Zhong-lin Chen; Xiao-chun Wang (Environmental Science and Pollution Research, 2020)

Alternative designs and tropical tree seedling growth performance landscapes - Samantha J. Worthy; Daniel C. Laughlin; Jenny Zambrano; María N. Umaña; Caicai Zhang; Luxiang Lin; Min Cao; Nathan G. Swenson (Ecology, 2020)
The functional trait values that constitute a whole‐plant phenotype interact with the environment to determine demographic rates. Current approaches often fail to explicitly consider trait × trait and trait × environment interactions, which may lead to missed information that is valuable for understanding and predicting the drivers of demographic rates and functional diversity. Here, we consider these interactions by modeling growth performance landscapes that span multidimensional trait spaces along environmental gradients. We utilize individual‐level leaf, stem, and root trait data combined with growth data from tree seedlings along soil nutrient and light gradients in a hyper‐diverse tropical rainforest. We find that multiple trait combinations in phenotypic space (i.e., alternative designs) lead to multiple growth performance peaks that shift along light and soil axes such that no single or set of interacting traits consistently results in peak growth performance. Evidence from these growth performance peaks also generally indicates frequent independence of above‐ and belowground resource acquisition strategies. These results help explain how functional diversity is maintained in ecological communities and question the practice of utilizing a single trait or environmental variable, in isolation, to predict the growth performance of individual trees.

An overview of COVID-19 - Yu Shi; Gang Wang; Xiao-peng Cai; Jing-wen Deng; Lin Zheng; Hai-hong Zhu; Min Zheng; Bo Yang; Zhi Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Muscovy Duck Reovirus Infection Disrupts the Composition of Intestinal Microbiota in Muscovy Ducklings - Xiuqin Chen; Min Zheng; Meiqing Huang; Shifeng Xiao; Fengqiang Lin; Shaoying Chen; Shilong Chen (Current Microbiology, 2020)

The nucleic acid positive rate and genotype distribution of human cytomegalovirus in human milk banks in China - Xiaoyu Min; Lin Wang; Aili Cui; Chunli Zhang; Dan Wang; Ying Liu; Zhenghong Li; Wenbo Xu (Archives of Virology, 2020)

Nanochemoprevention with therapeutic benefits: An updated review focused on epigallocatechin gallate delivery - Qiong-Qiong Yang; Xin-Lin Wei; Ya-Peng Fang; Ren-You Gan; Min Wang; Ying-Ying Ge; Dan Zhang; Li-Zeng Cheng; Harold Corke (Critical Reviews in Food Science and Nutrition, 2020)

Assessing dietary exposure risk to neonicotinoid residues among preschool children in regions of Taiwan - Min-Pei Ling; Huai-An Hsiao; Szu-Chieh Chen; Wei-Yu Chen; Wei-Chun Chou; Yi-Jun Lin; Shu-Han You; Ying-Fei Yang; Hsing-Chieh Lin; Chi-Yun Chen; Tien-Hsuan Lu; Chung-Min Liao (Environmental Science and Pollution Research, 2020)

Swelling characteristics of andesite foundation induced by water immersion and their influence on ballastless track subgrade - Jun-yi Duan; Guo-lin Yang; Min Hu; Xiao-qin Lei; Yu-liang Lin (Journal of Mountain Science, 2020)

Development of polyclonal-antibody-coated immunomagnetic beads for separation and detection of koi herpesvirus in large-volume samples - Min Zhang; Yingying Li; Hongli Jing; Na Wang; Shaoqiang Wu; Qing Wang; Xiangmei Lin (Archives of Virology, 2020)