Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders - Juanxian Cheng; Zhe Zhao; Liping Chen; Ying Li; Ruijing Du; Yan Wu; Qian Zhu; Ming Fan; Xiaotao Duan; Haitao Wu (Neuroscience Bulletin, 2022)

Common Subtype of Small Renal Mass MR Imaging Characterisation: A Medical Center Experience in Taiwan - Ming-Cheng Liu; Yi-Jui Liu; Yen-Ting Lin; Siu-Wan Hung; Jyh-Wen Chai; Si-Wa Chan; Kun-Yuan Chiu; Ya-Ling Tsou (Journal of Medical and Biological Engineering, 2022)
Purpose Many studies have shown that multiparametric magnetic resonance imaging (MRI) may be helpful for differentiating malignant renal cell carcinomas (RCCs) from benign lesions. However, the key imaging characteristics that differ between malignant and benign tumors still require further discussion. Methods We analyzed 60 adult patients diagnosed with 72 small renal masses (SRMs) who received preoperative MRI from 2014 to 2019 at a hospital in Taiwan. The MRI features included conventional MRI parameters, diffusion-weighted imaging (DWI) data, and dynamic contrast-enhanced (DCE) patterns, which were documented and compared among the four common subtypes: clear cell RCC (ccRCC), papillary RCC (pRCC), angiomyolipoma (AML) and other types of RCC. The apparent diffusion coefficient (ADC) values of high- and low-grade RCCs were also analyzed. Results The results show that ccRCC had higher T2-weighted signal intensity than the other three subgroups, a higher arterial wash-in index (AWI) and ADC value than AML and pRCC, and manifested a plateau ( n = 9, 25%) or washout (n = 27, 75%) enhancement pattern. AMLs exhibited more intravoxel fat than the other three subtype groups, and half of the AMLs (6 in 12) contained bulk fat. pRCC demonstrated a more progressive (n = 3, 60%) enhancement pattern than the other three subgroups. The ADC value of high-grade RCCs was significantly lower than that of low-grade RCCs. Conclusion These findings may indicate that multiparametric MRI is useful in differentiating among four common pathological types of SRMs, and the ADC value may be helpful in evaluating the histological grade of malignancy.

The combined toxicity of binary mixtures of antibiotics against the cyanobacterium Microcystis is dose-dependent: insight from a theoretical nonlinear combined toxicity assessment method - Yeyong Wang; Cheng Gao; Zhi Qu; Ming Li (Environmental Science and Pollution Research, 2022)

GIS-based spatial prediction of landslide using road factors and random forest for Sichuan-Tibet Highway - Cheng-ming Ye; Rui-long Wei; Yong-gang Ge; Yao Li; José Marcato Junior; Jonathan Li (Journal of Mountain Science, 2022)

Domestication obscures genomic estimates of population history - Chia‐Wei Lu; Cheng‐Te Yao; Chih‐Ming Hung (Molecular Ecology, 2022)
Domesticated species are valuable models to examine phenotypic evolution, and knowledge on domestication history is critical for understanding the trajectories of evolutionary changes. Sequentially Markov Coalescent models are often used to infer domestication history. However, domestication practices may obscure the signal left by population history, affecting demographic inference. Here we assembled the genomes of a recently domesticated species—the society finch—and its parent species—the white‐rumped munia—to examine its domestication history. We applied genomic analyses to two society finch breeds and white‐rumped munias to test whether domestication of the former resulted from inbreeding or hybridization. The society finch showed longer and more runs of homozygosity and lower genomic heterozygosity than the white‐rumped munia, supporting an inbreeding origin in the former. Blocks of white‐rumped munia and other ancestry in society finch genomes showed similar genetic distance between the two taxa, inconsistent with the hybridization origin hypothesis. We then applied two Sequentially Markov Coalescent models— psmc and smc++ —to infer the demographic histories of both. Surprisingly, the two models did not reveal a recent population bottleneck, but instead the psmc model showed a specious, dramatic population increase in the society finch. Subsequently, we used simulated genomes based on an array of demographic scenarios to demonstrate that recent inbreeding, not hybridization, caused the distorted psmc population trajectory. Such analyses could have misled our understanding of the domestication process. Our findings stress caution when interpreting the histories of recently domesticated species inferred by psmc , arguing that these histories require multiple analyses to validate.

Different scales of gene duplications occurring at different times have jointly shaped the NBS-LRR genes in Prunus species - Yan Zhong; Zhao Chen; Zong-Ming Cheng (Molecular Genetics and Genomics, 2022)
In this study, genome-wide identification, phylogenetic relationships, duplication time and selective pressure of the NBS-LRR genes, an important group of plant disease-resistance genes ( R genes), were performed to uncover their genetic evolutionary patterns in the six Prunus species. A total of 1946 NBS-LRR genes were identified; specifically, 589, 361, 284, 281, 318, and 113 were identified in Prunus yedoensis , P. domestica , P. avium , P. dulcis , P. persica and P. yedoensis var. nudiflora , respectively. Two NBS-LRR gene subclasses, TIR-NBS-LRR (TNL) and non-TIR-NBS-LRR (non-TNL), were also discovered. In total, 435 TNL and 1511 non-TNL genes were identified and could be classified into 30/55/75 and 103/158/191 multi-gene families, respectively, according to three different criteria. Higher Ks and Ka/Ks values were detected in TNL gene families than in non-TNL gene families. These results indicated that the TNL genes had more members involved in relatively ancient duplications and were affected by stronger selection pressure than the non-TNL genes. In general, the NBS-LRR genes were shaped by species-specific duplications, and lineage-specific duplications occurred at recent and relatively ancient periods among the six Prunus species. Therefore, different duplicated copies of NBS-LRRs can resist specific pathogens and will provide an R -gene library for resistance breeding in Prunus species.

YAP regulates porcine skin-derived stem cells self-renewal partly by repressing Wnt/β-catenin signaling pathway - Hong-Chen Yan; Yu Sun; Ming-Yu Zhang; Shu-Er Zhang; Jia-Dong Sun; Paul W. Dyce; Francesca Gioia Klinger; Massimo De Felici; Wei Shen; Shun-Feng Cheng (Histochemistry and Cell Biology, 2022)

Using computational fluid dynamic simulation with Flow-3D to reveal the origin of the mushroom stone in the Xiqiao Mountain of Guangdong, China - Jian-cheng Li; Wei Wang; Yan-ming Zheng; Xiao-hao Wen; Jing Feng; Li Sheng; Chen Wang; Ming-kun Qiu (Journal of Mountain Science, 2022)

Isolation and partial characterization of a novel bacteriocin from Pseudomonas azotoformans with antimicrobial activity against Pasterella multocida - Yu Wang; Shuang Lei; Inam Muhammad; Yu Jia; Cheng-guang He; Yi-Ming Wang; Yun-Hang Gao; Ling-Cong Kong; Hong-Xia Ma (Archives of Microbiology, 2022)

Williamsia soli sp. nov., an actinobacterium isolated from soil at a thermal power plant in Yantai, China - Ming-Jing Zhang; Xue-Han Li; Li-Yang Peng; Shuai-Ting Yun; Zhuo-Cheng Liu; Yan-Xia Zhou (Archives of Microbiology, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Thermal–Mechanical Modeling of a Rock/Proppant System to Investigate the Role of Shale Creep on Proppant Embedment and Fracture Conductivity - Ming Fan; Yanhui Han; Cheng Chen (Rock Mechanics and Rock Engineering, 2021)

Effective Thermal Conductivity Estimation of Fractured Rock Masses - Zheng-Wei Li; Yuan Liu; Shi-Ming Mei; Shi-Cheng Xing; Xiao-Kai Wang (Rock Mechanics and Rock Engineering, 2021)

Intramyocardial injection of human adipose-derived stem cells ameliorates cognitive deficit by regulating oxidative stress–mediated hippocampal damage after myocardial infarction - Tsung-Ming LEE; Cheng-Che LEE; Horng-Jyh HARN; Tzyy-Wen Chiou; Ming-Hsi CHUANG; Chun-Hung CHEN; Chi-Hsuan CHUANG; Po-Cheng LIN; Shinn-Zong LIN (Journal of Molecular Medicine, 2021)
Cognitive impairment is a serious side effect of post-myocardial infarction (MI) course. We have recently demonstrated that human adipose-derived stem cells (hADSCs) ameliorated myocardial injury after MI by attenuating reactive oxygen species (ROS) levels. Here, we studied whether the beneficial effects of intramyocardial hADSC transplantation can extend to the brain and how they may attenuate cognitive dysfunction via modulating ROS after MI. After coronary ligation, male Wistar rats were randomized via an intramyocardial route to receive either vehicle, hADSC transplantation (1 × 10 6 cells), or the combination of hADSCs and 3-Morpholinosydnonimine (SIN-1, a peroxynitrite donor). Whether hADSCs migrated into the hippocampus was assessed by using human-specific primers in qPCR reactions. Passive avoidance test was used to assess cognitive performance. Postinfarction was associated with increased oxidative stress in the myocardium, circulation, and hippocampus. This was coupled with decreased numbers of dendritic spines as well as a significant downregulation of synaptic plasticity consisting of synaptophysin and PSD95. Step-through latency during passive avoidance test was impaired in vehicle-treated rats after MI. Intramyocardial hADSC injection exerted therapeutic benefits in improving cardiac function and cognitive impairment. None of hADSCs was detected in rat’s hippocampus at the 3rd day after intramyocardial injection. The beneficial effects of hADSCs on MI-induced histological and cognitive changes were abolished after adding SIN-1. MI-induced ROS attacked the hippocampus to induce neurodegeneration, resulting in cognitive deficit. The remotely intramyocardial administration of hADSCs has the capacity of improved synaptic neuroplasticity in the hippocampus mediated by ROS, not the cell engraftment, after MI. Key messages Human adipose-derived stem cells (hADSCs) ameliorated injury after myocardial infarction by attenuating reactive oxygen species (ROS) levels. Intramyocardial administration of hADSCs remotely exerted therapeutic benefits in improving cognitive impairment after myocardial infarction. The improved synaptic neuroplasticity in the hippocampus was mediated by hADSC-inhibiting ROS, not by the stem cell engraftment.

An Image Quality Comparison Study Between Homemade and Commercial Dental Cone-Beam CT Systems - Trang Thi Ngoc Tran; David Shih-Chun Jin; Kun-Long Shih; Ming-Lun Hsu; Jyh-Cheng Chen (Journal of Medical and Biological Engineering, 2021)
Purpose Cone-beam computed tomography (CBCT) has been widely applied in dental and maxillofacial imaging. Several dental CBCT systems have been recently developed in order to improve the performance. This study aimed to evaluate the image quality of our prototype (YMU-DENT-P001) and compare with a commercial POYE Expert 3DS dental CBCT system (system A). Methods The Micro-CT Contrast Scale, Micro-CT Water and Micro-CT HA phantoms were used to evaluate the two CBCT systems in terms of contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), uniformity (U), distortion, and linearity in the relationship between image intensity and calcium hydroxyapatite concentration. We also fabricated a proprietary thin-wire phantom to evaluate full width at half maximum (FWHM) spatial resolution. Both CBCT systems used the same exposure protocol, and data analysis was performed in accordance with ISO standards using a proprietary image analysis platform. Results The SNR of our prototype system was nearly five times higher than that of system A (prototype: 159.85 ± 3.88; A: 35.42 ± 0.61; p < 0.05) and the CNR was three times higher (prototype: 329.39 ± 5.55; A: 100.29 ± 2.31; p < 0.05). The spatial resolution of the prototype (0.2446 mm) greatly exceeded that of system A (0.5179 mm) and image distortion was lower (prototype: 0.03 mm; system A: 0.285 mm). Little difference was observed between the two systems in terms of the linear relationship between bone mineral density (BMD) and image intensity. Conclusions Within the scope of this study, our prototype YMU-DENT-P001 outperformed system A in terms of spatial resolution, SNR, CNR, and image distortion.

Correction to: Ocean acidification alters the thermal performance curves of brooded larvae from the reef coral Pocillopora damicornis - Lei Jiang; You-Fang Sun; Yu-Yang Zhang; Yuan Tian; Xin-Ming Lei; Guo-Wei Zhou; Tao Yuan; Xiang-Cheng Yuan; Sheng Liu; Hui Huang (Coral Reefs, 2021)

The r-X1 deletion induces terminal deficiencies in the maize B chromosome - Yen-Hua Huang; Tzu-Che Lin; Wan-Yi Chiou; Ya-Ming Cheng (Chromosome Research, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Experimental study on the mechanical behavior of utility tunnel with flexible joints passing through active thrust fault - Lianjin Tao; Zhigang Wang; Shao An; Cheng Shi; Ming Shi; Ruilong Dong; Qiankun Cao (Arabian Journal of Geosciences, 2021)

Demographics of Scomberomorus commerson in the Central Taiwan Strait - Jinn-Shing Weng; Li-Chi Cheng; Yun-Sin Lo; Jen-Chieh Shiao; Jia-Sin He; Ming-An Lee; Kwang-Ming Liu (Journal of Marine Science and Engineering, 2021)
The narrow-barred Spanish mackerel Scomberomorus commerson is an economically essential species; however, few studies have investigated its demographic structure in the northwestern Pacific, which includes Taiwan’s waters. This study examined the growth parameters, age composition, mortality, and sex ratio of S. commerson catches by examining sagittal otoliths and other biological data collected in a 3-year project from June 2018 to June 2021. The transverse sections of sagittal otoliths exhibited alternating translucent and opaque zones, in annual cycles, and this observation was validated by otolith edge analysis. Opaque zones began to form in October; the growth peaked in December and lasted until March. Growth parameters were estimated for female (L∞ = 144.1 cm fork length [FL], k = 0.39 y−1, to = −0.85 y) and male (L∞ = 136.0 cm FL, k = 0.32 y−1, to = −1.49 y) specimens. The maximum recorded FL, body weight, and age were 159.0 cm, 27 kg, and 9.2 y for female and 135.0 cm, 17.8 kg, and 7.2 y for male specimens. Rapid growth was observed for both sexes, with FL reaching 66.8 ± 14.2 cm in female specimens and 70.1 ± 11.0 cm in male specimens during the first year of life. An age–length key based on the direct otolith aging and FL dataset (N = 646) was used to estimate the age composition of 3-year catches measured at landing (N = 16,133). The results verified that the S. commerson currently caught in the central Taiwan Strait are mainly young fish aged 1+ to 2+ y. The estimated fishing mortality (0.27 y−1) and exploitation rate (0.30) suggested that overfishing was not occurring in this stock. The findings of this study have helped clarify the population dynamics of the S. commerson in the Taiwan Strait, and the biological parameters reported herein can aid the management and conservation to ensure the sustainability of this species in this region.

Streptomyces luteolifulvus sp. nov., a novel actinomycete isolated from soil in Nanjing, China - Shanshan Zhao; Ming Cheng; Congyu Lin; He Liu; Zhengran Wang; Kai Zhang; Simin Song; Qian Yang (Antonie van Leeuwenhoek, 2021)

Vertical Nitrate Flux Induced by Kelvin–Helmholtz Billows Over a Seamount in the Kuroshio - Cristy S. Acabado; Yu-Hsin Cheng; Ming-Huei Chang; Chung-Chi Chen (Frontiers in Marine Science, 2021)
Kelvin–Helmholtz (KH) billows can facilitate microscale turbulent mixing around seamounts in the Kuroshio. This study sought to describe the influence of billow intensity (i.e., “intermittent and small” and “steady and large” billows) on vertical nitrate fluxes. KH billows led to turbulent kinetic energy dissipation rates [ε = O (10 –7 to 10 –6 ) W kg –1 ] and eddy diffusivities [K ρ = O (10 –4 to 10 –3 ) m 2 s –1 ] that were significantly stronger than those outside the billow depths. The mean nitrate flux estimated using K ρ in the billow depths had a maximal value of 10.0 mmol m –2 day –1 , which was much higher than estimates for the open ocean. The nitrate flux associated with the shallow KH billows at two vertical levels contributed to enrich the subsurface phytoplankton maximum, while the deeper billows closer to the summit were found to induce a large amount of nitrate flux from the deeper to the subsurface water. This study showed that KH billows make important contributions to seamount ecosystems, particularly in the cycling and vertical mixing of nutrients to make them available for potential downstream transport.

Meroterpenoids and alkaloids from Ganoderma australe - Jiao-Jiao Zhang; Yun Dong; Fu-Ying Qin; Yong-Ming Yan; Yong-Xian Cheng (Natural Product Research, 2021)

MiR-135-5p Alleviates Bone Cancer Pain by Regulating Astrocyte-Mediated Neuroinflammation in Spinal Cord through JAK2/STAT3 Signaling Pathway - Ming Liu; Xuefeng Cheng; Hong Yan; Jingli Chen; Caihua Liu; Zhonghui Chen (Molecular Neurobiology, 2021)

Ocean acidification alters the thermal performance curves of brooded larvae from the reef coral Pocillopora damicornis - Lei Jiang; You-Fang Sun; Yu-Yang Zhang; Yuan Tian; Xin-Ming Lei; Guo-Wei Zhou; Tao Yuan; Xiang-Cheng Yuan; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Plasticity of symbiont acquisition in new recruits of the massive coral Platygyra daedalea under ocean warming and acidification - Lei Jiang; Guo-Wei Zhou; Yu-Yang Zhang; Xin-Ming Lei; Tao Yuan; Ming-Lan Guo; Xiang-Cheng Yuan; Jian-Sheng Lian; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Resveratrol Mitigates Cerebral Ischemic Injury by Altering Levels of Trace Elements, Toxic Metal, Lipid Peroxidation, and Antioxidant Activity - Ju-Hai Ro; Chien-Chi Liu; Ming-Cheng Lin (Biological Trace Element Research, 2021)

Numerical Study on the Hydrodynamic Characteristics of a Double-Row Floating Breakwater Composed of a Pontoon and an Airbag - Xiaofei Cheng; Chang Liu; Qilong Zhang; Ming He; Xifeng Gao (Journal of Marine Science and Engineering, 2021)
By adding a cylindrical airbag on the leeward side of a cuboid pontoon, a new-type double-row floating breakwater is designed to improve the wave attenuation performance, and its hydrodynamic characteristics are studied through numerical simulations. First, based on the smoothed particle hydrodynamics (SPH) method, a numerical model used to simulate the interaction between waves and moored floating bodies is built. The fluid motion is governed by the Navier–Stokes equations. The motion of the floating body is computed according to Newton’s second law. The modified dynamic boundary condition is employed to treat the solid boundary. The lumped-mass method is adopted to implement the mooring system. Then, two physical model experiments on waves interaction with cuboid and dual cylindrical floating pontoons are reproduced. By comparing the experimental and numerical wave transmission coefficients, wave reflection coefficients, response amplitude operators and mooring force, the reliability of the numerical model is validated. Finally, the validated numerical model is applied to study the influence of separation distance and wave parameters on the hydrodynamic characteristics of the double-row floating breakwater. The results indicate that the optimal separation distance between pontoon and airbag is 0.75 times the wavelength. At such separation distance and within the concerned 1–4 m wave heights and 4–7 s wave periods, the pontoon-airbag system presents better wave attenuation performance than a single pontoon. This improvement weakens as wave height increases while it strengthens as the wave period increases. In addition, the double-row floating breakwater is more effective in a high-wave regime than in a low-wave regime. In the case of short waves, attention should be paid to the stability and mooring reliability of the seaward pontoon, while in the case of long waves, care needs to be taken of the leeward airbag.

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Non-coding RNA: insights into the mechanism of methamphetamine neurotoxicity - Ying-Jian Gu; Lei Chen; Lin Cheng; Ming-Yuan Zhou; Yun Wang (Molecular and Cellular Biochemistry, 2021)

The use of multi-pronged screening strategy to understand the epidemiology of carbapenemase-producing Enterobacteriaceae in Hong Kong: transition from epidemic to endemic setting - Shuk- Ching Wong; Veronica Wing- Man Chan; Germaine Kit-Ming Lam; Christine Ho-Yan AuYeung; Elaine Yin-Ling Leung; Simon Yung-Chun So; Jonathan Hon-Kwan Chen; Siddharth Sridhar; Anthony Raymond Tam; Ivan Fan-Ngai Hung; Pak- Leung Ho; Kwok- Yung Yuen; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

How are typical urban sewage treatment technologies going in China: from the perspective of life cycle environmental and economic coupled assessment - Hui Jiang; Qiang Jin; Panpan Cheng; Ming Hua; Zhen Ye (Environmental Science and Pollution Research, 2021)

Seismic responses of slopes with different angles in coral sand - Yan-ling Zhang; Xuan-ming Ding; Zhi-xiong Chen; Qi Wu; Cheng-long Wang (Journal of Mountain Science, 2021)

Ecological security pattern-based simulation for land use structure change: a case study in Ezhou City, China - Jing Ye; Zhijie Hou; Haiyan Ming; Yehuai Cheng (Frontiers of Earth Science, 2021)

Dynamic mechanical behavior and damage constitutive model of shales with different bedding under compressive impact loading - Xueru Fan; Ning Luo; Yishuo Yuan; Hanliang Liang; Cheng Zhai; Zhe Qu; Ming Li (Arabian Journal of Geosciences, 2021)

Detrimental impact of hypoxia on the mortality, growth, reproduction, and enzyme activities of planktonic mysid Neomysis awatschensis - Qiao-ning Wang; Xiao-dong Li; Tian Yan; Jing-jing Song; Ren-cheng Yu; Ming-jiang Zhou (Aquatic Ecology, 2021)

Hemoglobin Extracted From Perinereis aibuhitensis Acts as a Cell Culture Medium Supplement to Reduce Apoptosis - Qianyu Huo; Jing Liu; You Cheng; Bin Cao; Ming Lei; Yunde Liu (Frontiers in Marine Science, 2021)
The environmental oxygen concentration is a crucial factor affecting cell proliferation. Owing to the reversible binding property of hemoglobin to oxygen, it can be utilized to regulate the oxygen concentration in vitro , and its ability to reduce apoptosis can be evaluated. In this study, a process comprising isolation, purification, and extraction was used to obtain hemoglobin from Perinereis aibuhitensis , a polychaete invertebrate. Extracts were separated and characterized using sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Extract component identity was confirmed by matrix-assisted laser desorption time-of-flight mass spectrometry analysis, with the molecular weight determined as 412,216.6875 Da. The oxygen carrying capacity of P. aibuhitensis hemoglobin was comparable with that of human hemoglobin. P. aibuhitensis hemoglobin remarkably downregulated the apoptosis rate. Reactive oxygen species (ROS) assays confirmed the reduction in ROS production, enabling a better elucidation of the mechanism underlying the decrease in apoptosis. These results suggested that P. aibuhitensis hemoglobin is a natural oxygen carrier, that, owing to its low-cost and accessibility, can be considered a candidate for culture medium supplement to reduce the apoptosis rate.

Experimental and Numerical Characterization of Lower Huron Shale as a Heterogeneous Material - Ming Fan; Yanhui Han; Xinyu Tan; Liang Fan; Ellen S. Gilliland; Nino Ripepi; Cheng Chen (Rock Mechanics and Rock Engineering, 2021)

Remelting of a Neoproterozoic arc root: origin of the Pulang and Songnuo porphyry Cu deposits, Southwest China - Dian-Zhong Wang; Ruizhong Hu; Pete Hollings; Xian-Wu Bi; Hong Zhong; Li-Chuan Pan; Cheng-Biao Leng; Ming-Liang Huang; Jing-Jing Zhu (Mineralium Deposita, 2021)

Patient Confidential Information Transmission Using the Integration of PSO-Based Biomedical Signal Steganography and Threshold-Based Compression - Shih-Ying Chen; Shan-Ju Lin; Ming-Cheng Tsai; Ming-Dar Tsai; Yih-Jing Tang; Shuo-Tsung Chen; Li-Hsiang Wang (Journal of Medical and Biological Engineering, 2021)

Mediation Effect of Health Beliefs in the Relationship Between Health Knowledge and Uptake of Mammography in a National Breast Cancer Screening Program in Taiwan - Hui-Min Hsieh; Wei-Chieh Chang; Cheng-Ting Shen; Yi Liu; Fang-Ming Chen; Ya-Ting Kang (Journal of Cancer Education, 2021)

Chitosan-based hydrogels to treat hydrofluoric acid burns and prevent infection - Shu-Wei Huang; Fang-Ching Yeh; You-Ren Ji; Ying-Fu Su; Ying-shih Su; Ming-Hsien Chiang; Shian-Chiuan Tzeng; Chien-Yao Fu; Aristine Cheng; Yung-Chih Wang; Yi-Tzu Lee (Drug Delivery and Translational Research, 2021)

Enrichment of marine productivity utilizing steelmaking slag: managing conflicting stakeholders’ interests in Taiwan - Yung-Sheng Chen; Ming-Sheng Ko; Yu-Cheng Wang; Ping Chen; Ta-Kang Liu (Aquaculture International, 2021)

The developmental regulator PatD modulates assembly of the cell‐division protein FtsZ in the cyanobacterium Anabaena sp. PCC 7120 - Li Wang; Tian‐Cai Niu; Ana Valladares; Gui‐Ming Lin; Ju‐Yuan Zhang; Antonia Herrero; Wen‐Li Chen; Cheng‐Cai Zhang (Environmental Microbiology, 2021)
Summary FtsZ is a tubulin‐like GTPase that polymerizes to initiate the process of cell division in bacteria. Heterocysts are terminally differentiated cells of filamentous cyanobacteria that have lost the capacity for cell division and in which the ftsZ gene is downregulated. However, mechanisms of FtsZ regulation during heterocyst differentiation have been scarcely investigated. The patD gene is NtcA dependent and involved in the optimization of heterocyst frequency in Anabaena sp. PCC 7120. Here, we report that the inactivation of patD caused the formation of multiple FtsZ‐rings in vegetative cells, cell enlargement, and the retention of peptidoglycan synthesis activity in heterocysts, whereas its ectopic expression resulted in aberrant FtsZ polymerization and cell division. PatD interacted with FtsZ, increased FtsZ precipitation in sedimentation assays, and promoted the formation of thick straight FtsZ bundles that differ from the toroidal aggregates formed by FtsZ alone. These results suggest that in the differentiating heterocysts, PatD interferes with the assembly of FtsZ. We propose that in Anabaena FtsZ is a bifunctional protein involved in both vegetative cell division and regulation of heterocyst differentiation. In the differentiating cells PatD‐FtsZ interactions appear to set an FtsZ activity that is insufficient for cell division but optimal to foster differentiation.

Acute exposure to microcystin-LR induces hepatopancreas toxicity in the Chinese mitten crab (Eriocheir sinensis) - Cheng Chi; Xia-Wei Yu; Cai-Yan Zhang; Jia-Dai Liu; Ming-Wen Ye; Ding-Dong Zhang; Wen-Bin Liu (Archives of Toxicology, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

In-Situ Seawater Gamma Spectrometry with LaBr3 Detector at a Nuclear Power Plant Outlet - Daowei Dou; Zhi Zeng; Wen Yu; Ming Zeng; Wu Men; Feng Lin; Hao Ma; Jianping Cheng; Junli Li (Journal of Marine Science and Engineering, 2021)
In a nuclear emergency, the application of in situ spectrometers for monitoring environmental radioactivity is significantly important, as information on the type and activity of radionuclides released from the accident can be obtained quickly. However, in emergency environmental radiological monitoring, a balance between energy resolution and detecting efficiency must be considered in selecting an appropriate detector. In this study, in situ gamma spectrometry was conducted with the LaBr3 detector to determine the radioactivity of seawater at the discharging outlet of a coastal nuclear power plant in southeast China. The results show that the LaBr3 scintillator has excellent energy resolution and detection efficiency, making it a promising detector for emergency monitoring.

An underlying mechanism of qE deficiency in marine angiosperm Zostera marina - Wei Zhao; Quan Sheng Zhang; Ying Tan; Zhe Liu; Ming Yu Ma; Meng Xin Wang; Cheng Ying Luo (Photosynthesis Research, 2021)

Enhancement of IUdR Radiosensitization in Cancer Therapy by Low-Energy Transmission X Ray Irradiation - Chien-Chih Ke; Jia-Je Li; Hsueh-Peng Wu; Wen-Wang Kuo; Yi-An Chen; Cheng-Hsiu Lu; Hsin-Ell Wang; Shih-Ming Hsu; Ya-Ju Hsieh; Ren-Shyan Liu (Journal of Medical and Biological Engineering, 2021)

Adsorption of volatile benzene series compounds by surface-modified glass fibers: kinetics, thermodynamic adsorption efficiencies, and mechanisms - Rui Guo; Sijing Jiang; Ming Hu; Yuhang Zhan; Kun Cheng; Gaigai Duan (Environmental Science and Pollution Research, 2021)

Does tourism industry agglomeration reduce carbon emissions? - Can Huang; Jin-Wei Wang; Chien-Ming Wang; Jin-Hua Cheng; Juan Dai (Environmental Science and Pollution Research, 2021)

TOC determination of Zhangjiatan shale of Yanchang formation, Ordos Basin, China, using support vector regression and well logs - Xin Liu; Yuhong Lei; Xiaorong Luo; Xiangzeng Wang; Kaiyuan Chen; Ming Cheng; Jintao Yin (Earth Science Informatics, 2021)

Proton Pump Inhibitor Exposure and Acute Myocardial Infarction Risk: A Nested Cohort Study - Hsiang-Jung Tseng; Chih-Ming Cheng; Shih-Jen Tsai; Wei-Chen Lin; Ya-Mei Bai; Chia-Fen Tsai; Tung-Ping Su; Cheng-Ta Li; Tzeng-Ji Chen; Mu-Hong Chen (Cardiovascular Toxicology, 2021)

A transcription factor TaTCP20 regulates the expression of Ppd-D1b in common wheat - Fan Wei; Tianqi Song; Jianfei Zhou; Jie Cheng; Ruibo Li; Ming Yu; Yunrui Zhang; Yang Yu; Bo Zhang; Xiaoke Zhang (Plant Biotechnology Reports, 2021)

A Fully-Automatic Segmentation of the Carpal Tunnel from Magnetic Resonance Images Based on the Convolutional Neural Network-Based Approach - Tai-Hua Yang; Cheng-Wei Yang; Yung-Nien Sun; Ming-Huwi Horng (Journal of Medical and Biological Engineering, 2021)
Purpose Carpal tunnel syndrome is one of the common peripheral neuropathies. For magnetic resonance imaging, segmentation of the carpal tunnel and its contents, including flexor tendons and the median nerve for magnetic resonance images is an important issue. In this study, a convolutional neural network (CNN) model, which was modified by the original DeepLabv3 + model to segment three primary structures of the carpal tunnel: the carpal tunnel, flexor tendon, and median nerve. Methods To extract important feature maps for segmentation of the carpal tunnel, flexor tendon, and median nerve, the proposed CNN model termed modified DeepLabv3 + uses DenseNet-121 as a backbone and adds dilated convolution to the original spatial pyramid pooling module. A MaskTrack method was used to refine the segmented results generated by modified DeepLabv3 + , which have a small and blurred appearance. For evaluation of the segmentation results, the average Dice similarity coefficients (ADSC) were used as the performance index. Results Sixteen MR images corresponding to different subjects were obtained from the National Cheng Kung University Hospital. Our proposed modified DeepLabv3 + generated the following ADSCs: 0.928 for carpal tunnel, 0.872 for flexor tendons and 0.785 for the median nerve. The ADSC value of 0.8053 generated the MaskTrack that 0.22 ADSC measure were improved for measuring the median nerve. Conclusions The experimental results showed that the proposed modified DeepLabv3 + model can promote segmentations of the carpal tunnel and its contents. The results are superior to the results generated by original DeepLabv3 + . Additionally, MaskTrack can also effectively refine median nerve segmentations.

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers improved the outcome of patients with severe COVID-19 and hypertension - Xiao Meng; Ya Liu; Chenchen Wei; Kai Zhang; Yi Zhang; Ming Zhong; Cheng Zhang; Yun Zhang (Science China Life Sciences, 2021)

Association between functional brain alterations and neuropsychological scales in male chronic smokers using resting-state fMRI - Jun-Cheng Weng; Shih-Yu Huang; Ming-Shih Lee; Ming-Chou Ho (Psychopharmacology, 2021)

ZEB1: New advances in fibrosis and cancer - Lin Cheng; Ming-Yuan Zhou; Ying-Jian Gu; Lei Chen; Yun Wang (Molecular and Cellular Biochemistry, 2021)

Crenobacter intestini sp. nov., Isolated from the Intestinal Tract of Konosirus punctatus - Song-Biao Shi; Jia-Fa Wu; Li-Fang Yang; Ming-Guo Jiang; Cai-Mi Gao; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Carbon isotope variations of modern soils in the eastern margin of the Tibetan Plateau and their controlling factors - Lin Qi; Yan-song Qiao; Zong-xiu Liu; Sha-sha Peng; Yu Cheng; Yan Wang; Xu-jiao Zhang; Ming-zhong Tian; Shuai-bin Yang; Wen-bin Bai (Journal of Mountain Science, 2021)

Three new sesquiterpenoids with cytotoxic activity from Artemisia argyi - Li Zhang; Yong-Ming Yan; Shao-Xiang Wang; Zhe Ren; Yong-Xian Cheng (Natural Product Research, 2021)

Prediction of sound pressure fluctuations in the start-up phase of thermoacoustic oscillations under external perturbation - Zi-Hua Liu; Hao Zhou; Cheng-Fei Tao; Muhammad Waryal Dahri; Ming-Xi Zhou (Waste Disposal & Sustainable Energy, 2021)

An Insight into the Excavation-Induced Stress Paths on Mechanical Response of Weak Interlayer Zone in Underground Cavern Under High Geostress - Shu-Qian Duan; Quan Jiang; Guo-Feng Liu; Jie-Cheng Xiong; Po Gao; Ding-Ping Xu; Ming-Yu Li (Rock Mechanics and Rock Engineering, 2021)

Pseudomonas laoshanensis sp. nov., isolated from peanut field soil - Ming-Qing Wang; Chu-Shu Zhang; Li-Na Yu; Wei-Qiang Yang; Kun Jiao; Kui-Jie Gong; Xiao-Yuan Chi; Jie Bi; Yu Song; Qing-Li Yang; Jian-Cheng Zhang; Gui-Wen Yang; et al. (Archives of Microbiology, 2021)

Spatial distribution of atmospheric bioaerosols in Beijing, Hangzhou and Wuhan, China - Xuezheng Ma; Qi Zhang; Keyang Liu; Liping Zhang; Manman Zhang; Xin Zhao; Chunya Zhou; Jinke Li; Ming Cheng; Lili Li; Kongxin Hu; Jinsong Li; et al. (Aerobiologia, 2021)

Corrigendum: Quantifying Coral Reef Resilience to Climate Change and Human Development: An Evaluation of Multiple Empirical Frameworks - Ashley H. Y. Bang; Chao-Yang Kuo; Colin Kuo-Chang Wen; Kah-Leng Cherh; Ming-Jay Ho; Nien-Yun Cheng; Yen-Chia Chen; Chaolun Allen Chen (Frontiers in Marine Science, 2021)

Changes in arthropod community but not plant quality benefit a specialist herbivore on plants under reduced water availability - Po-An Lin; Chia-Ming Liu; Jia-Ang Ou; Cheng-Han Sun; Wen-Po Chuang; Chuan-Kai Ho; Natsuko Kinoshita; Gary W. Felton (Oecologia, 2021)

Diversity-oriented synthesis and antifungal activities of novel pimprinine derivative bearing a 1,3,4-oxadiazole-5-thioether moiety - Zi-Long Song; Yun Zhu; Jing-Rui Liu; Shu-Ke Guo; Yu-Cheng Gu; Xinya Han; Hong-Qiang Dong; Qi Sun; Wei-Hua Zhang; Ming-Zhi Zhang (Molecular Diversity, 2021)

Sustained effects of one-time sewage sludge addition on rice yield and heavy metals accumulation in salt-affected mudflat soil - Wengang Zuo; Yanchao Bai; Ming Lv; Zehui Tang; Cheng Ding; Chuanhui Gu; Yuhua Shan; Qigen Dai; Min Li (Environmental Science and Pollution Research, 2021)

Quantifying Coral Reef Resilience to Climate Change and Human Development: An Evaluation of Multiple Empirical Frameworks - Ashley H. Y. Bang; Chao-Yang Kuo; Colin Kuo-Chang Wen; Kah-Leng Cherh; Ming-Jay Ho; Nien-Yun Cheng; Yen-Chia Chen; Chaolun Allen Chen (Frontiers in Marine Science, 2021)
The integrity of coral reefs has increasingly been threatened by human development and climate change. As a result, the concept of ecological resilience – an ecosystem's capability to resist and recover from environmental stressors – has become an important aspect of coral reef conservation. In this study, coral reef resilience was quantitatively scored in Kenting National Park (KNP), Taiwan, using four different assessment frameworks: the first uses the opinions of local reef experts, the second includes metrics specific to the local reef context, the third combines the previous two approaches, and the fourth relies solely on ecological metrics from biodiversity surveys. To evaluate the accuracy of each assessment, the resulting resilience scores were compared with historical coral recovery rates, which served as a proxy for resilience. While each approach to measuring resilience has its merits and drawbacks, the picture of resilience became clearest when a few key indicators were included to reflect core ecosystem processes. Trends in resilience scores varied depending on the makeup of the assessment's indicators, and there was little correlation between the baseline metrics measured using different data collection methods. However, all resilience assessment trends indicated that KNP's Nanwan area is high in resilience. This is likely due to the effects of local tidally-induced upwelling, which significantly relieve the growing thermal stress placed on surrounding coral communities. Ultimately, the most successful assessments were those that empirically quantified ecological processes and local factors with only a few indicators, rather than broader approaches that measured many indicators. These findings are particularly relevant for reef managers to consider as they develop and employ resilience-based management strategies.

Calcium-sensing receptor in the development and treatment of pulmonary hypertension - Ming-Yuan Zhou; Lin Cheng; Lei Chen; Ying-Jian Gu; Yun Wang (Molecular Biology Reports, 2021)

Phytochemical and antitumor studies on Cynanchum mongolicum (Maxim.) Kom - Yong-Cheng Yang; Yan-Ming Wang; Zi-Jian Rong; Li-Na Hong; Qian Zhang; Jing-Ming Jia; An-Hua Wang (Natural Product Research, 2020)

Electro-Acupuncture Inhibits p66Shc-Mediated Oxidative Stress to Facilitate Functional Recovery After Spinal Cord Injury - Ming Cheng; Xiaojing Wu; Fei Wang; Bo Tan; Jiang Hu (Journal of Molecular Neuroscience, 2020)

Melatonin ameliorates spatial memory and motor deficits via preserving the integrity of cortical and hippocampal dendritic spine morphology in mice with neurotrauma - Xiao-Jing Lin; Ruoxu Liu; Chenyi Li; Xueqing Yi; Bo Fu; M. J. Walker; Xiao-Ming Xu; Gang Sun; Cheng-Hsien Lin (Inflammopharmacology, 2020)

Identification of immune-related gene signature predicting survival in the tumor microenvironment of lung adenocarcinoma - Mengnan Zhao; Ming Li; Zhencong Chen; Yunyi Bian; Yuansheng Zheng; Zhengyang Hu; Jiaqi Liang; Yiwei Huang; Jiacheng Yin; Cheng Zhan; Mingxiang Feng; Qun Wang (Immunogenetics, 2020)

Characteristics of discontinuities in Heifangtai landslide area in Gansu, China - Bin Li; Qiang Xu; Qiang Cheng; Tian-Xiang Liu; Ming-Gao Tang; Guang Zheng; Hai-Yan Wang (Applied Geophysics, 2020)

Sulfide ore prospecting in carbon-containing stratum using comprehensive time-domain induced polarization and controlled-source audio-frequency magnetotellurics - Ren-Bin Sun; Li-Xia Chu; Gui-Bin Zhang; Qiu-Ming Cheng; Yun-Chuan Xiang; Bin Hu; Chang-Rong Zhang; Jian-Fu Li; Yi-Jun Zhao (Applied Geophysics, 2020)

Anxiety is associated with increased risk for atrial cardiopathy - Zhaolu Wang; Huiyuan Qin; Guilin Chen; Yan Dai; Yingyuan Cai; Xi Cheng; Yun Qian; Ming Chu; Xiaowei Lu (Acta Neurologica Belgica, 2020)

Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions - Xiuxiu Li; Zhuo Chen; Guomin Zhang; Hongwei Lu; Peng Qin; Ming Qi; Ying Yu; Bingke Jiao; Xianfeng Zhao; Qiang Gao; Hao Wang; Yunyu Wu; et al. (Science China Life Sciences, 2020)

Lagged response of Adélie penguin (Pygoscelis adeliae) abundance to environmental variability in the Ross Sea, Antarctica - Xintong Chen; Xiao Cheng; Baogang Zhang; Hao Meng; Di Wu; Miao Zhang; Ming Ji; Xianglan Li (Polar Biology, 2020)

One-pot synthesis of substituted pyrrole–imidazole derivatives with anticancer activity - Ming Zhang; Yong Ding; Hong-Xia Qin; Zhi-Gang Xu; Hai-Tao Lan; Dong-Lin Yang; Cheng Yi (Molecular Diversity, 2020)

Optimizing the MIC breakpoints of amoxicillin and tetracycline for antibiotic selection in the rescue therapy of H. pylori with bismuth quadruple regimen - Ming-Tsung Hsieh; Wei-Lun Chang; Chung-Tai Wu; Hsiao-Bai Yang; Hsin-Yu Kuo; Meng-Ying Lin; Hsiu-Chi Cheng; Yu-Chin Tsai; Bor-Shyang Sheu (European Journal of Clinical Pharmacology, 2020)

Cerebral Organoids Repair Ischemic Stroke Brain Injury - Shu-Na Wang; Zhi Wang; Tian-Ying Xu; Ming-He Cheng; Wen-Lin Li; Chao-Yu Miao (Translational Stroke Research, 2020)
Stroke is the second leading cause of death and main cause of disability worldwide, but with few effective therapies. Although stem cell-based therapy has been proposed as an exciting regenerative medicine strategy for brain injury, there are limitations. The developed cerebral organoids (COs) represent a promising transplantation source for stroke that remains to be answered. Here, we transplanted COs at 55 days and explored the feasibility in the rat middle cerebral artery occlusion (MCAO) model of stroke. COs transplantation at 6 h or even 24 h after MCAO significantly reduces brain infarct volume and improves neurological motor function. Transplanted COs show the potential of multilineage differentiation to mimic in vivo cortical development, support motor cortex region-specific reconstruction, form neurotransmitter-related neurons, and achieve synaptic connection with host brain via in situ differentiation and cell replacement in stroke. Cells from transplanted COs show extensive migration into different brain regions along corpus callosum. The mechanisms underlying COs transplantation therapy are also associated with enhanced neurogenesis, synaptic reconstruction, axonal regeneration and angiogenesis, and decreased neural apoptosis with more survival neurons after stroke. Moreover, COs transplantation promotes predominantly exogenous neurogenesis in the transplantation periphery of ipsilateral cortex and predominantly endogenous neurogenesis in the hippocampus and subventricular zone. Together, we demonstrate the efficacy and underlying mechanisms of COs transplantation in stroke. This preliminary but promising study provides first-hand preclinical evidence for COs transplantation as a potential and effective intervention for stroke treatment.

Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice - Qi Yang; Li Luo; Ting Sun; Le Yang; Li-Fei Cheng; Yan Wang; Qing-Qing Liu; An Liu; Hai-Yan Liu; Ming-Gao Zhao; Sheng-Xi Wu; Bin Feng (Psychopharmacology, 2020)

Knockdown of Amphiregulin Triggers Doxorubicin-Induced Autophagic and Apoptotic Death by Regulating Endoplasmic Reticulum Stress in Glioblastoma Cells - I-Neng Lee; Jen-Tsung Yang; Ming-Ju Hsieh; Cheng Huang; Hsiu-Chen Huang; Yu-Ju Ku; Yu-Ping Wu; Kuan-Chieh Huang; Jui-Chieh Chen (Journal of Molecular Neuroscience, 2020)

Arbuscular mycorrhizal fungal species identity governs plant water content and soil aggregation improvements under wet-dry climate conditions - Yan Wang; Dan Xing; Chao Bin Luo; Fang Zhang; Cheng Ming Zhang (Environmental Science and Pollution Research, 2020)

Introgression of perennial growth habit from Lophopyrum elongatum into wheat - Juliya Abbasi; Jiale Xu; Hamid Dehghani; Ming-Cheng Luo; Karin R. Deal; Patrick E. McGuire; Jan Dvorak (Theoretical and Applied Genetics, 2020)

Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study - Ming-Cheng Wang; Ahmad Imran Zaydi; Wei-Hung Lin; Jin-Seng Lin; Min-Tze Liong; Jiunn-Jong Wu (Probiotics and Antimicrobial Proteins, 2020)

New gravimetric-only and hybrid geoid models of Taiwan for height modernisation, cross-island datum connection and airborne LiDAR mapping - Cheinway Hwang; Hung-Jui Hsu; W. E. Featherstone; Ching-Chung Cheng; Ming Yang; Wenhsuan Huang; Chong-You Wang; Jiu-Fu Huang; Kwo-Hwa Chen; Chi-Hsun Huang; Hechin Chen; Wen-Yi Su (Journal of Geodesy, 2020)

Lacustrine record from the eastern Tibetan Plateau associated with Asian summer monsoon changes over the past ~ 6 ka and its links with solar and ENSO activity - Guodong Ming; Weijian Zhou; Peng Cheng; Hong Wang; Feng Xian; Yunchong Fu; Shugang Wu; Hua Du (Climate Dynamics, 2020)

Potential probiotic of Lactobacillus strains isolated from the intestinal tracts of pigs and feces of dogs with antibacterial activity against multidrug-resistant pathogenic bacteria - Chuen-Fu Lin; Meng-Yi Lin; Chao-Nan Lin; Ming-Tang Chiou; Jia-Wen Chen; Kai-Chieh Yang; Ming-Cheng Wu (Archives of Microbiology, 2020)

(±) Gancochlearols A and B: cytotoxic and COX-2 inhibitory meroterpenoids from Ganoderma cochlear - Fu-Ying Qin; Yong-Ming Yan; Zheng-Chao Tu; Yong-Xian Cheng (Natural Product Research, 2020)

Two new diprenylated flavanones from Derris laxiflora Benth - Hui-Chi Huang; Shih-Chang Chien; Ching-Chuan Kuo; Ming-Der Wu; Ming-Jen Cheng; Jih-Jung Chen; Hsi-Lin Chiu; Yueh-Hsiung Kuo (Natural Product Research, 2020)

Selective mGluR1 Negative Allosteric Modulator Reduces Blood–Brain Barrier Permeability and Cerebral Edema After Experimental Subarachnoid Hemorrhage - Cheng Zhang; Ming Jiang; Wei-qi Wang; Shi-jun Zhao; Yan-xin Yin; Qiong-jie Mi; Ming-feng Yang; Yu-qiang Song; Bao-liang Sun; Zong-yong Zhang (Translational Stroke Research, 2020)

A Near Infrared Spectroscopy System for Assessing Rehabilitation on Peripheral Arterial Occlusion Patients - Shao-Hung Lu; Cheng-Lun Tsai; Tieh-Cheng Fu; Po-Hung Chang; Shao-Ming Lu (Journal of Medical and Biological Engineering, 2020)
Purpose A near-infrared spectroscopy system was developed to evaluate peripheral arterial occlusive disease (PAOD). The wireless device can take measurements when patients are doing rehabilitation exercise. Methods Two LED modules with wavelengths of 740 nm, 808 nm and 850 nm were placed over 32 mm away from the photodiode to detect the deep backscattering from muscle tissue. The absorbance difference from the extent of tissue oxygenation was extracted using a modified Beer’s law. Measurements taken on different muscle groups were applied to determine which branch of artery is occluded. Results The changes in oxygenation of gastrocnemius and tibialis anterior muscle were recorded when PAOD patients were riding a stationary bicycle. The drop in oxygenation with exercise generally should recover within 15 min of continuing exercise. Otherwise, the artery is not capable to provide enough blood supply to the exercising muscles. Since gastrocnemius is the primary muscle used in biking exercise, the compensatory vasodilation in gastrocnemius leads to hypoperfusion in tibialis anterior muscle. Conclusion This NIRS system is helpful for detecting the changes in tissue oxygenation during exercise. Muscle hypoxia was more obvious during exercise when the artery had some degree of occlusion.

Basin-Wide Initial Water Rights Allocation Model Considering Both the Quantity and Quality of Water - Zongzhi Wang; Lingling Zhang; Liang Cheng; Kelin Liu; Y-Ming Wei (Environmental Modeling & Assessment, 2020)

Distribution and risk of mercury in the sediments of mangroves along South China Coast - Rui-Fei Ma; Hao Cheng; Aniefiok Inyang; Ming Wang; You-Shao Wang (Ecotoxicology, 2020)

Nakamurella albus sp. nov.: A Novel Actinobacterium Isolated from a Lichen Sample - Long-Qian Jiang; De-Feng An; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Lei Lang; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2020)

Naphthalene exerts non-target effects on the abundance of active fungi by stimulating basidiomycete abundance - Li-ying Lan; Li Zhang; Ya Shen; Jian Zhang; Wan-qin Yang; Zhen-feng Xu; Yang Liu; Shu-qin He; Wei Zhou; Han Li; Li-xia Wang; Si-ning Liu; et al. (Journal of Mountain Science, 2020)

The trichome-specific acetolactate synthase NtALS1 gene, is involved in acylsugar biosynthesis in tobacco (Nicotiana tabacum L.) - Ai-Xia Chang; Biao Chen; Ai-Guo Yang; Ri-Sheng Hu; Quan-Fu Feng; Ming Chen; Xiao-Ning Yang; Cheng-Gang Luo; Yang-Yang Li; Yuan-Ying Wang (Planta, 2020)

Metal bioavailability during the periodic drying and rewetting process of littoral anoxic sediment - Cheng Liu; Ming Kong; Lei Zhang; Kaining Chen; Xiaozhi Gu; Xiaoming Hao (Journal of Soils and Sediments, 2020)

Field observation and simulation experiments on nutrient transformation during phytoplankton-derived particulate matter deposition - Ming Kong; Cheng Liu; Jianying Chao; Longmian Wang; Yuexiang Gao; Fuquang Peng; Xueting Xu; Tianlun Han; Peifang Wang; Chao Wang (Environmental Science and Pollution Research, 2020)

Dredging method effects on sediment resuspension and nutrient release across the sediment-water interface in Lake Taihu, China - Chao Chen; Ming Kong; Yi-Yao Wang; Qiu-Shi Shen; Ji-Cheng Zhong; Cheng-Xin Fan (Environmental Science and Pollution Research, 2020)

Toxicity assessment of electrochemical advanced oxidation process-treated groundwater from a gas station with petrochemical contamination - How-Ran Chao; Danielle E. Que; Alisha C. Aquino; Yan-You Gou; Lemmuel L. Tayo; Yi-Hsien Lin; Ming-Hsien Tsai; Fu-Lin Hsu; I-Cheng Lu; Sheng-Lun Lin; Natwat Srikhao; Cherng-Gueih Shy; et al. (Environmental Monitoring and Assessment, 2020)

Targeted Intravenous Nanoparticle Delivery: Role of Flow and Endothelial Glycocalyx Integrity - Ming J. Cheng; Ronodeep Mitra; Chinedu C. Okorafor; Alina A. Nersesyan; Ian C. Harding; Nandita N. Bal; Rajiv Kumar; Hanjoong Jo; Srinivas Sridhar; Eno E. Ebong (Annals of Biomedical Engineering, 2020)

Structure and Functional Diversity of Surface Bacterioplankton Communities in an Overwintering Habitat for Large Yellow Croaker, Pseudosciaena crocea, of the Southern East China Sea - Wen Yang; Shi-Zhan Zheng; Shou-Heng Zhou; Li Zhao; Jin-Yong Zhu; Betina Lukwambe; Regan Nicholaus; Cheng-Hua Li; Zhong-Ming Zheng (Frontiers in Marine Science, 2020)

Population Genetic Analysis for Stock Enhancement of Silver Sea Bream (Rhabdosargus sarba) in Taiwan - Te-Hua Hsu; Chang-Wen Huang; Hung-Tai Lee; Yi-Hsuan Kuo; Kwang-Ming Liu; Cheng-Hui Lin; Hong-Yi Gong (Fishes, 2020)
Stock enhancement is a method for replenishing depleted wild finfish populations by supplementing them with hatchery-raised fish. In Taiwan, silver sea bream (Rhabdosargus sarba) is a predominant commercial species involved in stock enhancement projects. Although management agencies conduct stock enhancement projects, there are a lot of private releases without records. Stock enhancement is performed by the private aquaculture sector without accurate genetic records, potentially leading to unintended consequences for wild populations. We analyzed the genetics of 459 wild and 701 hatchery-reared specimens from nine batches produced by various hatcheries. Wild and hatchery-reared samples could be considered two separate clades by using a set of stable and informative microsatellite markers including type I (from gene introns and 3′UTR) and type II markers (randomly picked up from genome). Type I microsatellite markers could more sensitively reflect the loss of genetic diversity more than type II markers in the domestication process. All specimens were considered native by using mtDNA COI and microsatellites. The genetic composition of the wild population is relatively simple, and the estimated low contribution rate of the hatchery stock (1.3–10.9%; 6–50/459) indicated a weak but significant genetic effect of stock enhancement. Therefore, establishing standards for the stock enhancement of silver sea bream for more effective supplementation of wild populations is imperative.

Outflow sediment concentration forecasting by integrating machine learning approaches and time series analysis in reservoir desilting operation - Ming-Jui Chang; Gwo-Fong Lin; Fong-Zuo Lee; Yi-Cheng Wang; Peng-An Chen; Ming-Chang Wu; Jihn-Sung Lai (Stochastic Environmental Research and Risk Assessment, 2020)

Mapping and characterization of major QTL for spike traits in common wheat - Cheng-Hao Kuang; Xiao-Fang Zhao; Ke Yang; Zhi-Peng Zhang; Li Ding; Zhi-En Pu; Jian Ma; Qian-Tao Jiang; Guo-Yue Chen; Ji-Rui Wang; Yu-Ming Wei; You-Liang Zheng; et al. (Physiology and Molecular Biology of Plants, 2020)

P-wave velocity structures of the crust across the Southern Taiwan Strait imaged by using air-gun data recorded from ocean-bottom seismometers - Tan K. Wang; Jia Ming Deng; Jing Wang; Yu Hsuan Cheng; Zhi Zhao Xie; Yi Feng Zhang (Marine Geophysical Research, 2020)

Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China - Cheng-yi Lin; Die Li; Jie-ming Lu; Zhe-bin Yu; Yao Zhu; Peng Shen; Meng-ling Tang; Ming-juan Jin; Hong-bo Lin; Li-ming Shui; Kun Chen; Jian-bing Wang (Environmental Science and Pollution Research, 2020)

The maize B chromosome is capable of expressing microRNAs and altering the expression of microRNAs derived from A chromosomes - Yen-Hua Huang; Shu-Fen Peng; Yao-Pin Lin; Ya-Ming Cheng (Chromosome Research, 2020)

Impacts of Climate and Nutrients on Carbon Sequestration Rate by Wetlands: A Meta-analysis - Caifeng Cheng; Min Li; Zhenshan Xue; Zongsheng Zhang; Xianguo Lyu; Ming Jiang; Hongri Zhang (Chinese Geographical Science, 2020)

Molecular Survey and Genetic Diversity of Babesia spp. and Theileria spp. in Cattle in Gansu Province, China - Ming Sun; Guiquan Guan; Zhijie Liu; Jinming Wang; Duoquan Wang; Shufang Wang; Chao Ma; Shengzhong Cheng; Hong Yin; Jianxun Luo (Acta Parasitologica, 2020)

Design, synthesis and cholinesterase inhibitory activity of α -mangostin derivatives - Xiao-Qian Chi; Bo Hou; Liu Yang; Cheng-Ting Zi; Yong-Feng Lv; Jin-Yu Li; Fu-Cai Ren; Ming-Yan Yuan; Jiang-Miao Hu; Jun Zhou (Natural Product Research, 2020)

CmCYC2-like transcription factors may interact with each other or bind to the promoter to regulate floral symmetry development in Chrysanthemum morifolium - Cunquan Yuan; Di Huang; Yi Yang; Ming Sun; Tangren Cheng; Jia Wang; Huitang Pan; Qixiang Zhang (Plant Molecular Biology, 2020)

Luminescent Coordination Polymer for Picric Acid Detection and Treatment on Spinal Cord Injury Model Via Upregulating the trka Expression - Cheng-Hu Wang; Bin Sheng; Zhi Zhang; Ming Deng; Jin-Ju Xue; Yong-Gang Ma (Journal of Fluorescence, 2020)

Genome-wide identification and characterization of long non-coding RNAs during differentiation of visceral preadipocytes in rabbit - Kun Du; Guo-Ze Wang; An-yong Ren; Ming-cheng Cai; Gang Luo; Xian-bo Jia; Shen-qiang Hu; Jie Wang; Shi-Yi Chen; Song-Jia Lai (Functional & Integrative Genomics, 2020)

AAV/BBB-Mediated Gene Transfer of CHIP Attenuates Brain Injury Following Experimental Intracerebral Hemorrhage - Shuo Zhang; Zheng-wei Hu; Hai-yang Luo; Cheng-yuan Mao; Mi-bo Tang; Yu-sheng Li; Bo Song; Yao-he Wang; Zhong-xian Zhang; Qi-meng Zhang; Li-yuan Fan; Yao Zhang; et al. (Translational Stroke Research, 2020)

Genome-wide introgression from a bread wheat × Lophopyrum elongatum amphiploid into wheat - Jiale Xu; Le Wang; Karin R. Deal; Tingting Zhu; Ramesh K. Ramasamy; Ming-Cheng Luo; Julia Malvick; Frank M. You; Patrick E. McGuire; Jan Dvorak (Theoretical and Applied Genetics, 2020)

Phytochemicals and biological activities of species from the genus Maytenus - Lei Zhang; Ming-Yue Ji; Bin Qiu; Qin-Yu Li; Ke-Yong Zhang; Ji-Cheng Liu; Lian-Sheng Dang; Min-Hui Li (Medicinal Chemistry Research, 2020)

Appropriate Dynamically-Reinforced Supporting Time Determination in Relation to the Time Effect of Stress Field Evolution: A Case Study on the Deep Soft-Rock Roadway in China - Li Cong; Ying-ming Li; Xiang-rui Meng; Chun-liang Dong; Guang-ming Zhao; Rui Peng; Ji-cheng Xu (Geotechnical and Geological Engineering, 2020)

Impacts of elevated temperature and pCO2 on the brooded larvae of Pocillopora damicornis from Luhuitou Reef, China: evidence for local acclimatization - Lei Jiang; Ming-Lan Guo; Fang Zhang; Yu-Yang Zhang; Guo-Wei Zhou; Xin-Ming Lei; Xiang-Cheng Yuan; You-Fang Sun; Tao Yuan; Lin Cai; Jian-Sheng Lian; Sheng Liu; et al. (Coral Reefs, 2020)

Genetic removal of the CH1 exon leads to the production of hypofunctional heavy chain-only IgG2a in rats - Zhenrong Li; Ming Zhang; Shunan Zheng; Yu Song; Xueqian Cheng; Di Yu; Lijuan Du; Liming Ren; Haitang Han; Yaofeng Zhao (Transgenic Research, 2020)

Researches on the Internal Molecular Weight Uniformity of Chitosan Biomaterials - Xuqian Lang; Yang Li; Guohui Sun; Zhongzheng Zhou; Jing Li; Chao Feng; Ming Kong; Ya Liu; Xiaojie Cheng; Xiguang Chen (Journal of Ocean University of China, 2020)

Separation and preparation of N-glycans based on ammonia-catalyzed release method - Meifang Yang; Ming Wei; Chengjian Wang; Yu Lu; Wanjun Jin; Xi Gao; Cheng Li; Langhong Wang; Linjuan Huang; Zhongfu Wang (Glycoconjugate Journal, 2020)

Reproductive strategy of bachelors in a snub-nosed monkey (Rhinopithecus bieti) all-male unit - Cheng Guo; Alicia Krzton; Xiangdong Ruan; Zuofu Xiang; Ming Li (Primates, 2020)

Novel B-chromosome-specific transcriptionally active sequences are present throughout the maize B chromosome - Zi-Jie Hong; Jun-Xiang Xiao; Shu-Fen Peng; Yao-Pin Lin; Ya-Ming Cheng (Molecular Genetics and Genomics, 2020)

The linkage between methane production activity and prokaryotic community structure in the soil within a shale gas field in China - Yan-Qin Wang; Guang-Quan Xiao; Yong-Yi Cheng; Ming-Xia Wang; Bo-Ya Sun; Zhi-Feng Zhou (Environmental Science and Pollution Research, 2020)

MicroRNA-mediated responses to colchicine treatment in barley - Fang-Yao Sun; Lin Liu; Yi Yu; Xin-Ming Ruan; Cheng-Yu Wang; Qun-Wen Hu; De-Xiang Wu; Genlou Sun (Planta, 2020)

Spinal P2X7R contributes to streptozotocin-induced mechanical allodynia in mice - Cheng-ming Ni; He-ping Sun; Xiang Xu; Bing-yu Ling; Hui Jin; Yu-qiu Zhang; Zhi-qi Zhao; Hong Cao; Lan Xu (Journal of Zhejiang University-SCIENCE B, 2020)

CX3CR1 contributes to streptozotocin-induced mechanical allodynia in the mouse spinal cord - Cheng-ming Ni; Bing-yu Ling; Xiang Xu; He-ping Sun; Hui Jin; Yu-qiu Zhang; Hong Cao; Lan Xu (Journal of Zhejiang University-SCIENCE B, 2020)

Therapeutic Efficacy of Subcutaneous and Intraperitoneal Injections of a Single Dose of Human Umbilical Mesenchymal Stem Cells in Acute and Chronic Colitis in a Mouse Model - Yu-Lung Chang; Huei-Yu Lo; Shun-Ping Cheng; Kuo-Ting Chang; Xiu-Fang Lin; Sheng-Ping Lee; Jason Ma; Ming-Ling Kuo; Ming-Fa Hsieh; Chin-Kan Chan (Journal of Medical and Biological Engineering, 2020)

Performance Evaluation of a Novel Preclinical Micro-CT System In Vitro and In Vivo - Yi-Wen Lo; Chien-Chih Ke; Jhih-Shain Lee; Hsien-Chih Chiu; Cheng-Hsu Lu; Sih-Yu Chen; Wen-Chieh Yang; Ming-Chin Hu; Bang-Hung Yang; Wen-Sheng Huang; Ren-Shyan Liu (Journal of Medical and Biological Engineering, 2020)

Investigation of the fecal coliform plumes induced by river discharge and wind stress using a three-dimensional model - Wen-Cheng Liu; Hong-Ming Liu (Environmental Fluid Mechanics, 2020)

Molecular and morphological evidence for hybrid origin and matroclinal inheritance of an endangered wild rose, Rosa × pseudobanksiae (Rosaceae) from China - Cheng Zhang; Shi-Qi Li; Yu Zhang; Zhang-Ming Zhu; Jian-Quan Liu; Xin-Fen Gao (Conservation Genetics, 2020)

The false smut pathogen Ustilaginoidea virens requires rice stamens for false smut ball formation - Jing Fan; Jie Liu; Zhi‐You Gong; Pei‐Zhou Xu; Xiao‐Hong Hu; Jin‐Long Wu; Guo‐Bang Li; Juan Yang; Yu‐Qiu Wang; Yu‐Feng Zhou; Shuang‐Cheng Li; Li Wang; et al. (Environmental Microbiology, 2020)
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The disease is characterized by the transformation of individual rice florets into false smut balls, which is caused by the fungal pathogen Ustilaginoidea virens . To date, little is known about the host factors required for false smut ball formation by U . virens . In this study, we identified histological determinants for the formation of false smut balls by inoculating U . virens into rice floral mutants defective with respect to individual floral parts. The results showed that U . virens could form mature false smut balls in rice floral mutants with defective pistils, but failed to develop false smut balls in the superwoman mutant lacking stamens, identifying that U . virens requires rice stamens to complete its infection cycle. Comparative transcriptome analysis indicated a list of candidate host genes that may facilitate nutrient acquisition by U . virens from the rice stamens, such as SWEET11 , SWEET14 and SUT5 , and genes involved in the biosynthesis of trehalose and raffinose family sugars. These data pinpoint rice stamens as the key target organ of U . virens infection and provide a valuable starting point for dissecting the molecular mechanism of false smut ball formation.

The application of the ‘Gene-deletor’ technology in banana - Chun-hua Hu; Qiao-song Yang; Xiu-hong Shao; Tao Dong; Fang-cheng Bi; Chun-yu Li; Gui-ming Deng; Yi Li; Gan-jun Yi; Tong-xin Dou (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)
Banana ( Musa spp.) is an important tropical crop. Banana industry is under biotic and abiotic stresses such as Fusarium wilt, typhoon, cold stress. Genetic engineering offers a powerful strategy to create germplasm of banana with enhanced resistance. The safety of genetically modified organisms has become a bottleneck restricting the popularization and application of genetically modified technology. In this study, a candidate promoter, LEAFY (LFY) for expression and flower initiation in Arabidopsis , was cloned and constructed to ‘Gene-deletor’ vector. Histochemical β-glucuronidase (GUS) staining results showed that the ‘Gene-deletor’ vector driven by LFY promoter could lead to 88.5% excision efficiency from Arabidopsis seeds based on more than 200 T 3 progeny examined per event. GUS staining was found to be partially negative in transgenic bananas, however, polymerase chain reaction could still detect the presence of large fragments of the vector. These results suggest that although LFY promoter could not completely drive the ‘Gene-deletor’ vector to achieve the effect of complete elimination of exogenous gene in bananas, its efficiency of eliminating exogenous gene laid a theoretical foundation for cloning banana fruit-specific promoters, that is, ‘non-transgenic’ GM bananas.

miR-26 suppresses renal cell cancer via down-regulating coronin-3 - Xin Jun Wang; Zhi Jian Yan; Guang Cheng Luo; Yi Yan Chen; Pei Ming Bai (Molecular and Cellular Biochemistry, 2020)

Serum Uric Acid and Risk of Hemorrhagic Transformation in Patients with Acute Ischemic Stroke - Quhong Song; Yanan Wang; Yajun Cheng; Junfeng Liu; Chenchen Wei; Ming Liu (Journal of Molecular Neuroscience, 2020)

Transport and distribution of manganese in tidal estuarine system in Taiwan - Wen-Cheng Liu; Poi-Jiu Ken; Hong-Ming Liu (Environmental Science and Pollution Research, 2020)

Investigating the contaminant transport of heavy metals in estuarine waters - Wen-Cheng Liu; Hong-Ming Liu; Poi-Jiu Ken (Environmental Monitoring and Assessment, 2020)

Evolution and Current Applications of Robot-Assisted Fracture Reduction: A Comprehensive Review - Jing-Xin Zhao; Changsheng Li; Hongliang Ren; Ming Hao; Li-Cheng Zhang; Pei-Fu Tang (Annals of Biomedical Engineering, 2020)

Secondary metabolites from the fermented rice of the fungus Monascus purpureus and their bioactivities - Ho-Cheng Wu; Ming-Jen Cheng; Ming-Der Wu; Jih-Jung Chen; Yen-Lin Chen; Hsun-Shuo Chang; Kai-Ping Chen (Natural Product Research, 2019)

New hepatoprotective isoflavone glucosides from Pueraria lobata (Willd.) Ohwi - Yingjie Sun; Hongmin Zhang; Ming Cheng; Shijie Cao; Miao Qiao; Boli Zhang; Liqin Ding; Feng Qiu (Natural Product Research, 2019)

Correction to: Recombination between homoeologous chromosomes induced in durum wheat by the Aegilops speltoides Su1-Ph1 suppressor - Hao Li; Le Wang; Ming-Cheng Luo; Fang Nie; Yun Zhou; Patrick E. McGuire; Assaf Distelfeld; Xiongtao Dai; Chun-Peng Song; Jan Dvorak (Theoretical and Applied Genetics, 2019)

Recombination between homoeologous chromosomes induced in durum wheat by the Aegilops speltoides Su1-Ph1 suppressor - Hao Li; Le Wang; Ming-Cheng Luo; Fang Nie; Yun Zhou; Patrick E. McGuire; Assaf Distelfeld; Xiongtao Dai; Chun-Peng Song; Jan Dvorak (Theoretical and Applied Genetics, 2019)

Interception of sulfate deposition from a closed canopy to a forest gap edge canopy in a subalpine dragon spruce plantation - Yu Zhang; Fu-zhong Wu; Bo Tan; Zhen-feng Xu; Han Li; Jun-cheng Liu; Hai-rong Zhao; Si-yi Tan; Cheng-ming You; Wan-qin Yang (Journal of Mountain Science, 2019)

Hydrocarbon Geological Conditions and Exploration Potential of Mesozoic-Paleozoic Marine Strata in the South Yellow Sea Basin - Yong Yuan; Jianwen Chen; Jie Liang; Ming Xu; Baohua Lei; Yuxi Zhang; Qingsong Cheng; Jianqiang Wang (Journal of Ocean University of China, 2019)

Numerical investigation of the wind environment around tall buildings in a central business district - Pingzhi Fang; Deqian Zheng; Ming Gu; Haifeng Cheng; Bihong Zhu (Frontiers of Earth Science, 2019)

Cloud type identification for a landfalling typhoon based on millimeter-wave radar range-height-indicator data - Zhoujie Cheng; Ming Wei; Yaping Zhu; Jie Bai; Xiaoguang Sun; Li Gao (Frontiers of Earth Science, 2019)

Airborne Transmission of Influenza Virus in a Hospital of Qinhuangdao During 2017–2018 Flu Season - Xin Zhao; Weizhong Nie; Chunya Zhou; Ming Cheng; Chun Wang; Yongjie Liu; Jinke Li; Yunkai Qian; Xuezheng Ma; Liping Zhang; Lili Li; Kongxin Hu (Food and Environmental Virology, 2019)

Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice - Sha-Sha Zhang; Yu-Hua Tian; Song-Jun Jin; Wen-Cheng Wang; Jing-Xin Zhao; Xiao-Ming Si; Li Zhang; Hong Xu; Jing-Yu Jin (Psychopharmacology, 2019)

Do arbuscular mycorrhizal fungi help the native species Bidens biternata resist the invasion of Bidens alba? - Jun-Kang Cheng; Mao-Feng Yue; Heng-Rong Yang; Bao-Ming Chen; Guo-Rong Xin (Plant and Soil, 2019)

Failure mechanism of a mudstone slope embedded with steep anti-dip layered sandstones: case of the 2016 Yanchao catastrophic landslide in Taiwan - Cheng-Han Lin; Ching Hung; Meng-Chia Weng; Ming-Lang Lin; Ryosuke Uzuoka (Landslides, 2019)

Rapid evolution of α-gliadin gene family revealed by analyzing Gli-2 locus regions of wild emmer wheat - Naxin Huo; Tingting Zhu; Shengli Zhang; Toni Mohr; Ming-Cheng Luo; Jong-Yeol Lee; Assaf Distelfeld; Susan Altenbach; Yong Q. Gu (Functional & Integrative Genomics, 2019)

Remediation of TCE-contaminated groundwater using KMnO4 oxidation: laboratory and field-scale studies - Zong-Han Yang; Jiun-Hau Ou; Cheng-Di Dong; Chiu-Wen Chen; Wei-Han Lin; Chih-Ming Kao (Environmental Science and Pollution Research, 2019)

Implementation of the Land Surface Processes into a Vector Vorticity Equation Model (VVM) to Study its Impact on Afternoon Thunderstorms over Complex Topography in Taiwan - Chien-Ming Wu; Hsiao-Chun Lin; Fang-Yi Cheng; Mu-Hua Chien (Asia-Pacific Journal of Atmospheric Sciences, 2019)

Mitochondrial fission protein 1 up-regulation ameliorates senescence-related endothelial dysfunction of human endothelial progenitor cells - Hsueh-Hsiao Wang; Yih-Jer Wu; Ya-Ming Tseng; Cheng-Huang Su; Chin-Ling Hsieh; Hung-I Yeh (Angiogenesis, 2019)

Investigation of Oil Spills from Oil Tankers through Grey Theory: Events from 1974 to 2016 - Dong-Taur Su; Fu-Ming Tzu; Chung-Hung Cheng (Journal of Marine Science and Engineering, 2019)
An oil spill from a vessel is a critical maritime accident that can severely damage the environment. In this study; we utilize the basic construction of grey relational analysis to explore oil spill events statistics from 1974 to 2015 and successfully analyze the causes of incidents in 2016. The results illustrate that grey relational analysis effectively identifies the factors causing oil spills with an accuracy of over 96%. The research is aimed to reduce the marine accidents and predict the cause of oil spill in advance. The analysis is dealing with the incidents to approach the circumstance in various intensity of oil spill in the last 40 years. Moreover, an application of grey theory demonstrates accurate and reliable methodology to decision maker. Thus, the investigation can predict the causes of pollution from oil spill accidents in the future.

Resolving the phylogenetic position of Caeoma spp. that infect Rhododendron and Chrysomyxa from China - Chong Juan You; Lv Jiao Yang; Cheng Ming Tian (Mycological Progress, 2019)

MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway - Liang Sun; Zhong Li; Hanzhong Xue; Teng Ma; Cheng Ren; Ming Li; Yao Lu; He Sun; Kun Zhang (Molecular and Cellular Biochemistry, 2019)

Development of a Direction-Oriented Motion and Short-Sitting and Lying Tai Chi (DOM-SSLTC) Model for Function Recovery in Stroke Patients - Lian-Hui Lee; Hwai-Ting Lin; Nai-Wen Tsai; Yung-Chieh Yen; Cheng-Hsien Lu; Chun-Chung Lui; Hsien-Ming Chung; Kun-Chang Tsai; Shih-Pin Hsu; Huan-Wen Tsui (Journal of Medical and Biological Engineering, 2019)

Ottowia flava sp. nov., isolated from fish intestines - Song-Biao Shi; Gui-Ding Li; Li-Fang Yang; Cong Liu; Ming-Guo Jiang; Qin-Yuan Li; Jia-Fa Wu; Kun Zhang; Long-Qian Jiang; Nai-Kun Shen; Cheng-Lin Jiang; Yi Jiang (Antonie van Leeuwenhoek, 2019)

Fine mapping and candidate gene analysis of qhkw5-3, a major QTL for kernel weight in maize - Wenliang Li; Qinghe Bai; Weimin Zhan; Chenyu Ma; Shunyou Wang; Yuanyuan Feng; Mengdi Zhang; Ying Zhu; Ming Cheng; Zhangying Xi (Theoretical and Applied Genetics, 2019)

Paeoniflorin attenuates impairment of spatial learning and hippocampal long-term potentiation in mice subjected to chronic unpredictable mild stress - Si-Cheng Liu; Wei-Yan Hu; Wei-Yuan Zhang; Lu Yang; Yan Li; Zhi-Cheng Xiao; Ming Zhang; Zhi-Yong He (Psychopharmacology, 2019)

Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B - Fang-Shin Nian; Lei-Li Li; Chih-Ya Cheng; Pei-Chun Wu; You-Tai Lin; Cheng-Yung Tang; Bo-Shiun Ren; Chin-Yin Tai; Ming-Ji Fann; Lung-Sen Kao; Chen-Jee Hong; Jin-Wu Tsai (Molecular Neurobiology, 2019)

Isolation, structural elucidation and in vitro hepatoprotective activity of flavonoids from Glycyrrhiza uralensis - Ming Cheng; Liqin Ding; Hongfeng Kan; Hongmin Zhang; Benke Jiang; Yingjie Sun; Shijie Cao; Wei Li; Kazuo Koike; Feng Qiu (Journal of Natural Medicines, 2019)

Optimized aeration strategies for nitrogen removal efficiency: application of end gas recirculation aeration in the fixed bed biofilm reactor - Jia heng Zhou; Hao cheng Yu; Kai qiang Ye; Hong yu Wang; Yun jie Ruan; Jian ming Yu (Environmental Science and Pollution Research, 2019)

Application of a stable carbon isotope for identifying Broussonetia papyrifera pollen - Chien-Cheng Jung; Chuan-Pin Lee; Wen-Chi Wang; Ming-Chee Wu; Huey-Jen Su (Environmental Science and Pollution Research, 2019)

Self-rooted grafting influences the growth and cadmium accumulation characteristics in the post generation of Cosmos sulphureus - Jin Wang; Yumei Tan; Ming’an Liao; Lijin Lin; Yi Tang; Huifen Zhang; Hui Xia; Dong Liang; Qunxian Deng; Xiulan Lv; Cheng Chen; Wei Ren (Environmental Science and Pollution Research, 2019)

The Ribosomal Protein RPLP0 Mediates PLAAT4-induced Cell Cycle Arrest and Cell Apoptosis - Chun-Hua Wang; Lu-Kai Wang; Chang-Chieh Wu; Mao-Liang Chen; Ming-Cheng Lee; Yi-Ying Lin; Fu-Ming Tsai (Cell Biochemistry and Biophysics, 2019)

Experimental investigation on the mechanical characteristics of gas-bearing coal considering the impact of moisture - Ming-yi Chen; Yuan-ping Cheng; Jing-chun Wang; Hao-ran Li; Ning Wang (Arabian Journal of Geosciences, 2019)

Adult sacrococcygeal teratoma: a retrospective study over eight years at a single institution - Xiang-ming Xu; Feng Zhao; Xiao-fei Cheng; Wei-xiang Zhong; Jing-peng Liu; Wei-qin Jiang; Xiao-kai Yu; Jian-jiang Lin (Journal of Zhejiang University-SCIENCE B, 2019)

Neural response to betel quid cues in chewers: a functional magnetic resonance imaging study - Ming-Chou Ho; Guo-Joe Huang; Yeu-Sheng Tyan; Hsien-Chun Tseng; Jun-Cheng Weng (Brain Imaging and Behavior, 2019)

F‐box proteins MoFwd1, MoCdc4 and MoFbx15 regulate development and pathogenicity in the rice blast fungus Magnaporthe oryzae - Huan‐Bin Shi; Nan Chen; Xue‐Ming Zhu; Shuang Liang; Lin Li; Jiao‐Yu Wang; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2019)
Summary The Skp1‐Cul1‐F‐box‐protein (SCF) ubiquitin ligases are important parts of the ubiquitin system controlling many cellular biological processes in eukaryotes. However, the roles of SCF ubiquitin ligases remain unclear in phytopathogenic Magnaporthe oryzae . Here, we cloned 24 F‐box proteins and confirmed that 17 proteins could interact with MoSkp1, showing their potential to participate in SCF complexes. To determine their functions, null mutants of 21 F‐box‐containing genes were created. Among them, the F‐box proteins MoFwd1, MoCdc4 and MoFbx15 were found to be required for growth, development and full virulence. Fluorescent‐microscopy observations demonstrated that both MoFbx15 and MoCdc4 were localized to the nucleus, compared with MoFwd1, which was distributed in the cytosol. MoCdc4 and MoFwd1 bound to MoSkp1 via the F‐box domain, the deletion of which abrogated their function. Race tube and qRT‐PCR assays confirmed that MoFwd1 was involved in circadian rhythm by regulating transcription and protein stability of the core circadian clock regulator MoFRQ . Moreover, MoFWD1 also orchestrates conidial germination by influencing conidial amino acids pools and oxidative stress release. Overall, our results indicate that SCF ubiquitin ligases play indispensable roles in development and pathogenicity in M. oryzae .

Content, causes and analysis of heterocyclic amines in Chinese traditional braised chicken - Yiqun Cheng; Mingjun Yao; Zongshuai Zhu; Xiaoli Dong; Iftikhar Ali Khan; Jichao Huang; Xinghu Zhou; Ming Huang; Guanghong Zhou (Food Additives & Contaminants: Part A, 2019)

Quantification of cardiac pumping mechanics in rats by using the elastance–resistance model based solely on the measured left ventricular pressure and cardiac output - Chih-Hsien Wang; Ru-Wen Chang; En-Ting Wu; Chun-Yi Chang; Hsien-Li Kao; Ming-Shiou Wu; Ya-Jung Cheng; Yih-Sharng Chen; Kuo-Chu Chang (Pflügers Archiv - European Journal of Physiology, 2019)

Blood and seminal plasma mercury levels and predatory fish intake in relation to low semen quality - Chin-En Ai; Ching-Jen Li; Ming-Chien Tsou; Jun-Lin Chen; Hsing-Cheng Hsi; Ling-Chu Chien (Environmental Science and Pollution Research, 2019)

Food-derived antithrombotic peptides: Preparation, identification, and interactions with thrombin - Shuzheng Cheng; Maolin Tu; Hanxiong Liu; Guanghua Zhao; Ming Du (Critical Reviews in Food Science and Nutrition, 2019)

The Elastic–Plastic Damage Analysis of Underground Research Laboratory Excavation for Disposal of High Level Radioactive Waste - Ming-yang Ren; Qiang-yong Zhang; Chuan-cheng Liu; Dong Wu; Yan-zhi Ding (Geotechnical and Geological Engineering, 2019)

Thermostability of tropomyosins from the fast skeletal muscles of tropical fish species - Ming-Chih Huang; Cheng-Linn Lee; Yoshihiro Ochiai; Shugo Watabe (Fish Physiology and Biochemistry, 2019)

Nucleoside alkaloids with anti-platelet aggregation activity from the rhizomes of Ligusticum striatum - Zhong-Hui Pu; Juan Liu; Cheng Peng; Min Luo; Qin-Mei Zhou; Xiao-Fang Xie; Ming-Hua Chen; Liang Xiong (Natural Product Research, 2019)

New pyrazinoquinazoline alkaloids Isolated from a culture of Stenotrophomonas maltophilia QB-77 - Sheng-Yan Qian; Cai-Ling Yang; Afsar Khan; Rong-Xiang Chen; Ming-Song Wu; Li Tuo; Qian Wang; Jian-Guo Liu; Gui-Guang Cheng (Natural Product Research, 2019)

Overexpression of an ABA-dependent grapevine bZIP transcription factor, VvABF2, enhances osmotic stress in Arabidopsis - Jinyi Liu; Jinjin Chu; Chuangju Ma; Yueting Jiang; Yuanchun Ma; Jinsong Xiong; Zong-Ming Cheng (Plant Cell Reports, 2019)

First identification of cucumber mosaic virus infecting six fruit crops in China - Cheng-Ming Yu; Guo-Wei Geng; Xin-Ran Cao; Chen Yang; Zhe Qi; Shan-Shan Liu; Chang-Xiang Zhu; Xue-Feng Yuan (Journal of Plant Pathology, 2019)

Cutting after grafting affects the growth and cadmium accumulation of Nasturtium officinale - Xingyu Zhang; Fenqin Zhang; Jin Wang; Lijin Lin; Ming’an Liao; Yi Tang; Guochao Sun; Xun Wang; Xiulan Lv; Qunxian Deng; Cheng Chen; Wei Ren (Environmental Science and Pollution Research, 2019)

Epidemiological trends and virological traits of hepatitis B virus infection in pregnant women and neonates - Ting-Ting Peng; Qiu-E Cai; Min Yang; Shao-Ping Chen; Feng Chen; Miao Wang; Ling Peng; Gary Wong; Chen-Guang Shen; Wen-Bing Cheng; Sai-Yun Liu; Ya-Bai Peng; et al. (Archives of Virology, 2019)

Spatial and temporal evolution of landfast ice near Zhongshan Station, East Antarctica, over an annual cycle in 2011/2012 - Jiechen Zhao; Qinghua Yang; Bin Cheng; Matti Leppäranta; Fengming Hui; Surui Xie; Meng Chen; Yining Yu; Zhongxiang Tian; Ming Li; Lin Zhang (Acta Oceanologica Sinica, 2019)

Elaboration in type, primary structure, and bioactivity of polysaccharides derived from mollusks - Ling Chong Wang; Liu Qing Di; Jun Song Li; Li Hong Hu; Jian Ming Cheng; Hao Wu (Critical Reviews in Food Science and Nutrition, 2019)

Magnesium sulfate inhibits binding of lipopolysaccharide to THP-1 cells by reducing expression of cluster of differentiation 14 - Ya-Ying Chang; Tzu-Yu Lin; Ming-Chang Kao; Tsung-Ying Chen; Ching-Feng Cheng; Chih-Shung Wong; Chun-Jen Huang (Inflammopharmacology, 2019)

Identification of proteins differentially expressed in the gills of grass carp (Ctenopharyngodon idella) after hypoxic stress by two-dimensional gel electrophoresis analysis - Zhan-Ning Xu; Guo-Dong Zheng; Cheng-Bin Wu; Xia-Yun Jiang; Shu-Ming Zou (Fish Physiology and Biochemistry, 2019)

Effects of acclimation temperature on the thermal tolerance, hypoxia tolerance and swimming performance of two endangered fish species in China - Long-Yan Zhou; Shi-Jian Fu; Cheng Fu; Hong Ling; Xiu-Ming Li (Journal of Comparative Physiology B, 2019)

Long-term seasonal forecasting of a major migrant insect pest: the brown planthopper in the Lower Yangtze River Valley - Gao Hu; Ming-Hong Lu; Don R. Reynolds; Hai-Kou Wang; Xiao Chen; Wan-Cai Liu; Feng Zhu; Xiang-Wen Wu; Feng Xia; Miao-Chang Xie; Xia-Nian Cheng; Ka-Sing Lim; et al. (Journal of Pest Science, 2019)

Investigating suspended-sediment transport in a shallow lake using a three-dimensional hydrodynamic and sediment model - Wen-Cheng Liu; Hong-Ming Liu; Chih-Yu Chiu (Journal of Earth System Science, 2019)

Habitat selection of wintering cranes (Gruidae) in typical lake wetland in the lower reaches of the Yangtze River, China - Cheng Wang; Bin Dong; Ming Zhu; Hui Huang; Yu-huang Cui; Xiang Gao; Li-ping Liu (Environmental Science and Pollution Research, 2019)

Origin of the Mushroom Stone Forest at the southeastern foot of the Little Sangpu Mountain in eastern Guangdong, China: A palaeo-sea-level indicator or not? - Jian-cheng Li; Wei Wang; Yan-ming Zheng (Journal of Mountain Science, 2019)

Genome-wide identification of the HKT genes in five Rosaceae species and expression analysis of HKT genes in response to salt-stress in Fragaria vesca - Shichuang Zhang; Yuexia Tong; Yingjun Li; Zong-Ming Cheng; Yan Zhong (Genes & Genomics, 2019)