Testing the transfer functions for the Geonor T-200B and Chinese standard precipitation gauge in the central Qinghai—Tibet Plateau - Le-le Zhang; Li-ming Gao; Ji Chen; Lin Zhao; Ke-long Chen; Jing-yi Zhao; Guo-jun Liu; Ting-xi Song; Yan-kun Li (Journal of Mountain Science, 2022)

Aquapteridospora jiangxiensis, a new aquatic hyphomycetous fungus from a freshwater habitat in China - Su-Qin Peng; Yu-Lin Liu; Jun-En Huang; Xiao-Hong Li; Xin-Yi Yan; Hai-Yan Song; Yang Gao; Zhi-Jun Zhai; Yuan-Qiu Liu; Dian-Ming Hu (Archives of Microbiology, 2022)

Estrogenic and anti-neutrophilic inflammatory phenanthrenes from Juncus effusus L. - Hao-Chun Hu; Yi-Hong Tsai; Yu-Che Chuang; Kuei-Hung Lai; Yu-Ming Hsu; Tsong-Long Hwang; Chih-Chan Lin; Ferenc Fülöp; Yang-Chang Wu; Szu-Yin Yu; Yu-Ting Kuo; Fang-Rong Chang (Natural Product Research, 2022)

Characterization of Water Transport in Porous Building Materials Based on an Analytical Spontaneous Imbibition Model - Ming-Liang Qu; Sheng-Yue Lu; Qingyang Lin; Sajjad Foroughi; Zi-Tao Yu; Martin J. Blunt (Transport in Porous Media, 2022)

Cerebellar Oscillations in Familial and Sporadic Essential Tremor - Shi-Bing Wong; Yi-Mei Wang; Chih-Chun Lin; Scott Kun Geng; Nora Vanegas-Arroyave; Seth L. Pullman; Sheng-Han Kuo; Ming-Kai Pan (The Cerebellum, 2022)

Identification of the Largest SCA36 Pedigree in Asia: with Multimodel Neuroimaging Evaluation for the First Time - Yue Xie; Zhao Chen; Zhe Long; Rui-Ting Chen; Yi-Zheng Jiang; Ming-Jie Liu; Lin-Liu Peng; Hui-Rong Peng; Na Wan; Guangdong Zou; Chun-Rong Wang; Yu-Ting Shi; et al. (The Cerebellum, 2022)

An optimal integration of multiple machine learning techniques to real-time reservoir inflow forecasting - I.-Hang Huang; Ming-Jui Chang; Gwo-Fong Lin (Stochastic Environmental Research and Risk Assessment, 2022)

Lactobacillus plantarum PS128 Promotes Intestinal Motility, Mucin Production, and Serotonin Signaling in Mice - Chih-Ming Chen; Chien-Chen Wu; Chin-Lin Huang; Min-Yu Chang; Shih-Hsuan Cheng; Ching-Ting Lin; Ying-Chieh Tsai (Probiotics and Antimicrobial Proteins, 2022)
Lactobacillus plantarum PS128 has been reported as a psychobiotic to improve mental health through the gut–brain axis in experimental animal models. To explore its mechanism of action in the gut, this study aimed to analyze the effects of L. plantarum PS128 ingestion on naïve and loperamide (Lop)-induced constipation mice. We found that, in the two mouse models, the weight, number, and water content of feces in the L. plantarum PS128 group were higher than those in the vehicle control group. Histological observation revealed that L. plantarum PS128 increased the level of colonic mucins including the major mucin MUC2. In addition, the charcoal meal test showed that L. plantarum PS128 significantly increased the small intestine transit in naïve mice, but not in the Lop-treated mice. Since intestinal serotonin has been found to modulate motility, we further analyzed the expression of genes related to serotonin signal transduction in the small intestine of naïve mice. The results showed that L. plantarum PS128 significantly altered the expression levels of Tph1 , Chga , Slc6a4 , and Htr4 , but did not affect the expression levels of Tph2 , Htr3a , and Maoa . Furthermore, immunohistochemistry revealed that L. plantarum PS128 significantly increased the number of serotonin-containing intestinal cells in mice. Taken together, our results suggest that L. plantarum PS128 could promote intestinal motility, mucin production, and serotonin signal transduction, leading to a laxative effect in mice.

A Deep Mesencephalic Nucleus Circuit Regulates Licking Behavior - Di Zheng; Jia-Yu Fu; Meng-Yu Tang; Xiao-Dan Yu; Yi Zhu; Chen-Jie Shen; Chun-Yue Li; Shi-Ze Xie; Shan Lin; Minmin Luo; Xiao-Ming Li (Neuroscience Bulletin, 2022)

Using DeepLab v3 + -based semantic segmentation to evaluate platelet activation - Tsung-Chen Kuo; Ting-Wei Cheng; Ching-Kai Lin; Ming-Che Chang; Kuang-Yao Cheng; Yun-Chien Cheng (Medical & Biological Engineering & Computing, 2022)

Priming of rice defense against a sap-sucking insect pest brown planthopper by silicon - Yibin Lin; Xianhui Lin; Chaohui Ding; Ming Xia; Rongrong Xue; Zhongxiang Sun; Daoqian Chen; Keyan Zhu-Salzman; Rensen Zeng; Yuanyuan Song (Journal of Pest Science, 2022)

Estrogen Deficiency Aggravates Fluoride-Induced Liver Damage and Lipid Metabolism Disorder in Rats - Ya-ming Yu; Bian-hua Zhou; Yi-lin Yang; Cheng-Xiang Guo; Jing Zhao; Hong-wei Wang (Biological Trace Element Research, 2022)

Mechanical properties of cement soil improved using microbial-induced calcite precipitation - Shuang Li; Dong Liu; Ankit Garg; Peng Lin; Ming Huang (Arabian Journal of Geosciences, 2022)

Comparison of different inversion methods of D-T2 two-dimensional nuclear magnetic resonance logging and applicability analysis - Cheng-Lin Li; Mao-Jin Tan; Ke-Wen Wang; Feng Zhou; Ying-Ming Liu; Hai-Tao Zhang; Li-Zhi Xiao (Applied Geophysics, 2022)

Functional connections between bird eggshell stiffness and nest characteristics through risk of egg collision in nests - Chih‐Ming Hung; Shu‐Han Tsao; Pei‐Lin Chiang; Shang‐Ping Wu; Mao‐Ning Tuanmu; Jia‐Yang Juang (Ecology Letters, 2022)
Eggs and nests are two critical traits for the ecological success of birds. Their functional interactions, however, remain unclear. Here, we examined the functional connections between egg stiffness and nest attachment, site and structure for 1350 avian species. We revealed high eggshell stiffness for eggs in nests with a pensile attachment, located on non‐tree vegetation or having a domed shape, suggesting that birds produce stiffer eggs in response to higher egg‐collision risk in unstable or enclosed nests. Interdependence models suggested that the evolution of eggshell stiffness was more likely to be driven by than drive that of nest characters. Our results implied a trade‐off between investment in competing for established nesting niches and producing stiff eggs to explore novel niches with high collision risk, possibly mediated by predation or thermoregulation. This study highlights an overlooked connection between nests and eggshells that may have broadened the ecological niches of birds.

First report of chilli veinal mottle virus infecting tobacco in Guizhou, China - Yue Chen; Ting Ting Li; Jing Zhong; Li Ling Zhao; Ya Li Guo; Ye Chun Lin; Gui Gao; Yi Cao; Ming Ding (Journal of Plant Pathology, 2022)

Shear Instability and Turbulent Mixing in the Stratified Shear Flow Behind a Topographic Ridge at High Reynolds Number - Jia-Lin Chen; Xiao Yu; Ming-Huei Chang; Sen Jan; Yiing Jang Yang; Ren-Chieh Lien (Frontiers in Marine Science, 2022)
Observations on the lee of a topographic ridge show that the turbulence kinetic energy (TKE) dissipation rate due to shear instabilities is three orders of magnitude higher than the typical value in the open ocean. Laboratory-scale studies at low Reynolds number suggest that high turbulent dissipation occurs primarily within the core region of shear instabilities. However, field-scale studies indicate that high turbulence is mainly populated along the braids of shear instabilities. In this study, a high-resolution, resolving the Ozmidov-scale, non-hydrostatic model with Large Eddy Simulation (LES) turbulent closure is applied to investigate dominant mechanisms that control the spatial and temporal scales of shear instabilities and resulting mixing in stratified shear flow at high Reynolds number. The simulated density variance dissipation rate is elevated in the cusp-like bands of shear instabilities with a specific period, consistent with the acoustic backscatter taken by shipboard echo sounder. The vertical length scale of each cusp-like band is nearly half of the vertical length scale of the internal lee wave. However, it is consistent with instabilities originating from a shear layer based on linear stability theory. The model results indicate that the length scale and/or the period of shear instabilities are the key parameters to the mixing enhancement that increases with lateral Froude number Fr L , i.e. stronger shear and/or steeper ridge.

Cracking and Photo-Oxidation of Polyoxymethylene Degraded in Terrestrial and Simulated Marine Environments - Chih-Cheng Tang; Ying-Ting Chen; Yi-Ming Zhang; Huey-Ing Chen; Peter Brimblecombe; Chon-Lin Lee (Frontiers in Marine Science, 2022)
Marine plastic debris is an environmental problem, and its degradation into microplastics (1-5000 μm) introduces them into the food chain. In this study, small polyoxymethylene (global production ~3000 Tg per year) pellets were exposed in terrestrial and simulated marine environments to heat and light, resulting in cracking during decay with increasing IR absorption (OH-bonds). Furthermore, sunlight over three years reduced pellet mass and diameter (~10% and ~40%), initially yielding 100-300 μm fragments. Changes under UV irradiation were smaller as it could not penetrate into particle interiors. Characteristic spacing of surface striations (100-300 µm) initiated radial cracks to pellet interiors, and breakdown ultimately meant 95% of particles were <300 µm, which are potentially incorporated in marine turbidites.

First report of Euphorbia leaf curl virus infecting Passiflora edulis in Fujian province, China - Ting Ye; Guo-Hua Zheng; Ying Guo; Yan-Lin Ming (Journal of Plant Pathology, 2022)

The roles of leaf area index and albedo in vegetation induced temperature changes across China using modelling and observations - Na Dong; Ming Luo; Zhen Liu; Junying Sun; Kailu Wu; Hui Lin (Climate Dynamics, 2022)

Study on pressure arch effect of xigeda strata tunnel based on experiment and discrete element simulation - Ping Zhou; Yifan Jiang; Feicong Zhou; Jinyi Li; Ming Lin; Jiayong Lin; Zhijie Wang (Bulletin of Engineering Geology and the Environment, 2022)

Shinella oryzae sp. nov., a novel zearalenone-resistant bacterium isolated from rice paddy soil - Ruyu Gao; Juan Zheng; Wei Lu; Xiubin Ke; Ming Chen; Min Lin; Wei Zhang; Zhengfu Zhou (Antonie van Leeuwenhoek, 2022)

Dilated Generative Adversarial Networks for Underwater Image Restoration - Jao-Chuan Lin; Chih-Bin Hsu; Jen-Chun Lee; Chung-Hsien Chen; Te-Ming Tu (Journal of Marine Science and Engineering, 2022)
Underwater images often come with blurriness, lack of contrast, and low saturation due to the physics of light propagation, absorption, and scattering in seawater. To improve the visual quality of underwater images, many have proposed image processing methods that vary based on different approaches. We use a generative adversarial network (GAN)-based solution and generate high-quality underwater images equivalent to given raw underwater images by training our network to specify the differences between high-quality and raw underwater images. In our proposed method, which is called dilated GAN (DGAN), we add an additional loss function using structural similarity. Moreover, this method can not only determine the realness of the entire image but also functions with classification ability on each constituent pixel in the discriminator. Finally, using two different datasets, we compare the proposed model with other enhancement methods. We conduct several comparisons and demonstrate via full-reference and nonreference metrics that the proposed approach is able to simultaneously improve clarity and correct color and restores the visual quality of the images acquired in typical underwater scenarios.

Delayed rFGF21 Administration Improves Cerebrovascular Remodeling and White Matter Repair After Focal Stroke in Diabetic Mice - Yinghua Jiang; Jinrui Han; Yadan Li; Yinga Wu; Ning Liu; Samuel X. Shi; Li Lin; Jing Yuan; Shusheng Wang; Ming-Ming Ning; Aaron S. Dumont; Xiaoying Wang (Translational Stroke Research, 2022)

Duration of Induced Metallothionein is a Critical Factor in the Cadmium-Resistance Among Goldfish (Carassius auratus) and Common Carp (Cyprinus carpio) - Feng Ming Chang; Chia Hao Lin; Su Mei Wu (Bulletin of Environmental Contamination and Toxicology, 2022)

Road performance and microscopic action mechanism of low liquid limit silt solidified by AT curing agent - Jin Chang; Jian-Qing Jiang; Ming Lei; Shi-Lin Luo; Guang-Feng He; Jia-Yi Lin (Arabian Journal of Geosciences, 2022)

Anti-inflammatory constituents from Phyllostachys makinoi Hayata - Chia-Ching Liaw; Yu-Chi Lin; Shao-Yu Wu; Jenny Chun-Ling Kuo; Zhi-Hu Lin; Kai-Wei Lin; Huang Hui-Chi; Li-Ming Yang Kuo; Yao-Haur Kuo (Natural Product Research, 2022)

Towards a rapid assessment of highway slope disasters by using multidisciplinary techniques - Meng-Chia Weng; Cheng-Han Lin; Wen-Jie Shiu; Wei-An Chao; Chia-Chi Chiu; Ching-Fang Lee; Wei-Kai Huang; Che-Ming Yang (Landslides, 2022)
Mega-earthquakes and extreme climate events accompanied by intrinsic fragile geology lead to numerous landslides along mountain highways in Taiwan, causing enormous life and economic losses. In this study, a system for rapid slope disaster information integration and assessment is proposed with the aim of providing information on landslide occurrence, failure mechanisms, and subsequent landslide-affected areas to the highway authority rapidly. The functionality of the proposed system is deployed into three units: (1) geohazard rapid report (GeoPORT I), (2) multidisciplinary geological survey report (GeoPORT II), and (3) site-specific landslide simulation report (GeoPORT III). After landslide occurrence, the seismology-based monitoring network rapidly provides the initial slope disaster information, including preliminary location, event magnitude, earthquake activity, and source dynamics, within an hour. Within 3 days of the landslide, a multidisciplinary geological survey is conducted to collect high-precision topographical, geological, and remote-sensing data to determine the possible failure mechanism. After integrating the aforementioned information, a full-scale three-dimensional landslide simulation based on the discrete element method is performed within 10 days to reveal the failure process and to identify the areas potentially affected by subsequent disasters through scenario modeling. Overall, the proposed system can promptly provide comprehensive and objective information to relevant authorities after the event occurrence for hazard assessment. The proposed system was validated using a landslide event in the Central Cross-Island Highway of Taiwan.

Morphological and Molecular Characterization of Paragonimus skrjabini Complex from Yunnan, China: A Brief Report - Qiu-Hong Shu; Shu-De Li; Ming Tian; Yong Meng; Shu-Mei-Qi He; Min Zhu; Miao-Miao Wang; Wen-Lin Wang (Acta Parasitologica, 2022)
Purpose To perform environmental sampling and molecular identification of Paragonimus in endemic regions, which may help in minimizing transmission among humans. Methods Mountain crabs from the genus Potamiscus were collected and the encysted metacercariae were extracted and subjected to morphological identification, followed by animal inoculation in Sprague–Dawley (SD) rats. After 112 days of infection, animals were killed and adult worms were extracted from lungs and muscles. The morphology of adult worms was characterized by microscopy and molecular identification was done by polymerase chain reaction, followed by sequencing of cox1 and ITS2 genes. Phylogenetic analysis was done by maximum parsimony method. Results A total of 447 crabs were captured from the streams of Tongchang Town, Jinping County, Yunnan Province, China. The infection rate was found to be 41% (186 out of 447 crabs). The metacercariae of Paragonimus skrjabini was identified by the characteristics round or spherical encysted form measuring 410 to 460 × 400 to 460 µm. After animal infection in SD rats, adults were presumptively confirmed to be P. skrjabini , which was also confirmed by gene amplification and sequence analysis of cox1 and ITS2 regions. Paragonimus skrjabini clustered with previously reported P. skrjabini from Yunnan and Vietnam. The confidence values of their branches were > 95%. Phylogenetic analysis of the ITS2 region revealed two distinct clusters with distinct geographical grouping. Phylogenetic analysis with the combined data sets reiterated the geographical grouping with P. skrjabini from Yunnan clustering with strains from Vietnam. Conclusion Metacercariae of P. skrjabini was discovered in freshwater crabs in Yunnan province, China, and the strains were phylogenetically related to P. skrjabini from Vietnam.

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae - Ying‐Ying Cai; Jing‐Yi Wang; Xi‐Yu Wu; Shuang Liang; Xue‐Ming Zhu; Lin Li; Jian‐Ping Lu; Xiao‐Hong Liu; Fu‐Cheng Lin (Environmental Microbiology, 2022)
Summary The development and pathogenicity of the fungus Magnaporthe oryzae , the causal agent of destructive rice blast disease, require it to perceive external environmental signals. Opy2, an overproduction‐induced pheromone‐resistant protein 2, is a crucial protein for sensing external signals in Saccharomyces cerevisiae . However, the biological functions of the homologue of Opy2 in M. oryzae are unclear. In this study, we identified that MoOPY2 is involved in fungal development, pathogenicity, and autophagy in M. oryzae . Deletion of MoOPY2 resulted in pleiotropic defects in hyphal growth, conidiation, germ tube extension, appressorium formation, appressorium turgor generation, and invasive growth, therefore leading to attenuated pathogenicity. Furthermore, MoOpy2 participates in the Osm1 MAPK pathway and the Mps1 MAPK pathway by interacting with the adaptor protein Mst50. The interaction sites of Mst50 and MoOpy2 colocalized with the autophagic marker protein MoAtg8 in the preautophagosomal structure sites (PAS). Notably, the Δ Moopy2 mutant caused cumulative MoAtg8 lipidation and rapid GFP‐MoAtg8 degradation in response to nitrogen starvation, showing that MoOpy2 is involved in the negative regulation of autophagy activity. Taken together, our study revealed that MoOpy2 of M. oryzae plays an essential role in the orchestration of fungal development, appressorium penetration, autophagy and pathogenesis.

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Prevalence, complete genome, and metabolic potentials of a phylogenetically novel cyanobacterial symbiont in the coral‐killing sponge, Terpios hoshinota - Yu‐Hsiang Chen; Hsing‐Ju Chen; Cheng‐Yu Yang; Jia‐Ho Shiu; Daphne Z. Hoh; Pei‐Wen Chiang; Wenhua Savanna Chow; Chaolun Allen Chen; Tin‐Han Shih; Szu‐Hsien Lin; Chi‐Ming Yang; James Davis Reimer; et al. (Environmental Microbiology, 2022)
Summary Terpios hoshinota is an aggressive, space‐competing sponge that kills various stony corals. Outbreaks of this species have led to intense damage to coral reefs in many locations. Here, the first large‐scale 16S rRNA gene survey across three oceans revealed that bacteria related to the taxa Prochloron , Endozoicomonas , SAR116, Ruegeria , and unclassified Proteobacteria were prevalent in T . hoshinota . A Prochloron ‐related bacterium was the most dominant and prevalent cyanobacterium in T . hoshinota . The complete genome of this uncultivated cyanobacterium and pigment analysis demonstrated that it has phycobiliproteins and lacks chlorophyll b , which is inconsistent with the definition of Prochloron . Furthermore, the cyanobacterium was phylogenetically distinct from Prochloron , strongly suggesting that it should be a sister taxon to Prochloron . Therefore, we proposed this symbiotic cyanobacterium as a novel species under the new genus Candidatus Paraprochloron terpiosi. Comparative genomic analyses revealed that ‘Paraprochloron’ and Prochloron exhibit distinct genomic features and DNA replication machinery. We also characterized the metabolic potentials of ‘Paraprochloron terpiosi’ in carbon and nitrogen cycling and propose a model for interactions between it and T. hoshinota . This study builds a foundation for the study of the T . hoshinota microbiome and paves the way for better understanding of ecosystems involving this coral‐killing sponge.

Pollution characteristics, mechanism of toxicity and health effects of the ultrafine particles in the indoor environment: Current status and future perspectives - Muhammad Ubaid Ali; Siyi Lin; Balal Yousaf; Qumber Abbas; Mehr Ahmed Mujtaba Munir; Audil Rashid; Chunmiao Zheng; Xingxing Kuang; Ming Hung Wong (Critical Reviews in Environmental Science and Technology, 2022)

Correction to: Numerical Simulation of the Time-Dependent Mild-Slope Equation by the Generalized Finite Difference Method - Ting Zhang; Zhen-Huan Lin; Chuan Lin; Lin Liang; Chia-Ming Fan (Pure and Applied Geophysics, 2022)

Oxygen Metabolism-induced Stress Response Underlies Heart–brain Interaction Governing Human Consciousness-breaking and Attention - Xiao-Juan Xue; Rui Su; Ze-Feng Li; Xiao-Ou Bu; Peng Dang; Si-Fang Yu; Zhi-Xin Wang; Dong-Mei Chen; Tong-Ao Zeng; Ming Liu; Hai-Lin Ma; De-Long Zhang (Neuroscience Bulletin, 2022)

Common Subtype of Small Renal Mass MR Imaging Characterisation: A Medical Center Experience in Taiwan - Ming-Cheng Liu; Yi-Jui Liu; Yen-Ting Lin; Siu-Wan Hung; Jyh-Wen Chai; Si-Wa Chan; Kun-Yuan Chiu; Ya-Ling Tsou (Journal of Medical and Biological Engineering, 2022)
Purpose Many studies have shown that multiparametric magnetic resonance imaging (MRI) may be helpful for differentiating malignant renal cell carcinomas (RCCs) from benign lesions. However, the key imaging characteristics that differ between malignant and benign tumors still require further discussion. Methods We analyzed 60 adult patients diagnosed with 72 small renal masses (SRMs) who received preoperative MRI from 2014 to 2019 at a hospital in Taiwan. The MRI features included conventional MRI parameters, diffusion-weighted imaging (DWI) data, and dynamic contrast-enhanced (DCE) patterns, which were documented and compared among the four common subtypes: clear cell RCC (ccRCC), papillary RCC (pRCC), angiomyolipoma (AML) and other types of RCC. The apparent diffusion coefficient (ADC) values of high- and low-grade RCCs were also analyzed. Results The results show that ccRCC had higher T2-weighted signal intensity than the other three subgroups, a higher arterial wash-in index (AWI) and ADC value than AML and pRCC, and manifested a plateau ( n = 9, 25%) or washout (n = 27, 75%) enhancement pattern. AMLs exhibited more intravoxel fat than the other three subtype groups, and half of the AMLs (6 in 12) contained bulk fat. pRCC demonstrated a more progressive (n = 3, 60%) enhancement pattern than the other three subgroups. The ADC value of high-grade RCCs was significantly lower than that of low-grade RCCs. Conclusion These findings may indicate that multiparametric MRI is useful in differentiating among four common pathological types of SRMs, and the ADC value may be helpful in evaluating the histological grade of malignancy.

Structure reassignment of two triterpenes with CASE algorithms and DFT chemical shift predictions - Zhi-Kang Duan; Tian-Ming Lv; Guan-Shan Song; Yu-Xi Wang; Bin Lin; Xiao-Xiao Huang (Natural Product Research, 2022)

Two new triterpenoid-chromone hybrids from the rhizomes of Actaea cimicifuga L. (syn. Cimicifuga foetida L.) and their cytotoxic activities - Qiang-Qiang Shi; Ya Gao; Jing Lu; Lin Zhou; Ming-Hua Qiu (Natural Product Research, 2022)

Joint-Tissue Integrative Analysis Identified Hundreds of Schizophrenia Risk Genes - Yong Wu; Xiao-Lin Yu; Xiao Xiao; Ming Li; Yi Li (Molecular Neurobiology, 2022)

The difference in the intracellular Arg/Lys-rich and EHLVY motifs contributes to distinct subcellular distribution of HAI-1 versus HAI-2 - Nanxi Huang; Robert B. Barndt; Dajun D. Lu; Qiaochu Wang; Shih-Ming Huang; Jehng-Kang Wang; Ping-Ying Chang; Chao-Yang Chen; Je-Ming Hu; Hui-Chen Su; Michael D. Johnson; Chen-Yong Lin (Human Cell, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Bioactive compounds derived from the marine-derived fungus MCCC3A00951 and their influenza neuraminidase inhibition activity in vitro and in silico - Shun-Zhi Liu; Feng-Ming He; Yan-lin Bin; Chu-Fang Li; Bao-Ying Xie; Xi-Xiang Tang; Ying-Kun Qiu (Natural Product Research, 2021)

Investigation on Improving Strategies for Navigation Safety in the Offshore Wind Farm in Taiwan Strait - Yuh-Ming Tsai; Cherng-Yuan Lin (Journal of Marine Science and Engineering, 2021)
The Taiwan Strait, to the west of Taiwan, is rich in wind energy resources and has the greatest offshore wind power potential in the world. Therefore, Taiwan has been actively expanding its offshore wind power industry in this area in recent years and expects to achieve the total installed capacity to 15.6 GW by 2035. Due to the large vessel traffic flow in Western Taiwan’s sea area, wind farms will inevitably reduce the navigable space and shadow some existing marine aids to navigation, thus worsening navigation safety. An approach using a fault tree analysis was used to carry out analysis of collision risk between ship-to-ship and ship-to-turbine. The vessel density distribution and traffic flow within the open sea of offshore wind farms would further increase to curtail the available navigable space. The shadowing effects along navigation channels would thereafter be worsened to raise the probability of collision risks in the sea. The results of the fault tree analysis revealed that if the ship is out of control, the time allowed to provide assistance is rather short, leading to the increase of collision risk extent between ships and wind turbines. Moreover, the study also found that unfit functions of the Vessel Traffic Service System and navigation aids and frequently and arbitrarily crossing the navigation channel of fishery vessels are the main causes of ship collisions. In order to effectively improve the navigation safety, competitive strategies for navigation safety are investigated and evaluated in this study. These strategies include making a complete plan for utilizing the whole sea, integrating the offshore vessel traffic service and management system, providing remote pilotage services, and building salvage vessels. The above promising strategies would enhance the navigation safety within the open sea. Collision risk might occur once marine accident occurs and no salvage vessel is available.

Species Composition and Assemblages of Ichthyoplankton in Sansha Bay, Fujian Province, China - Yan Jiang; Bai-an Lin; Hao-yang He; Guang-mao Ding; Li-ting Yan; Ge Zhang; Min Liu; Lian-ming Zheng (Frontiers in Marine Science, 2021)
Sansha Bay (26.40−27.00°N, 119.50−120.20°E) is a typical semi-enclosed bay, located in northern Fujian Province, China, and adjacent to the East China Sea. The ichthyoplankton species composition and assemblage structure were investigated based on monthly sampling at 25 stations in April−September 2019, covering the important spring and summer spawning seasons in the region. Sampling was conducted in the first 3−5 days of the full moon or new moon phases using a standard plankton net through horizontal and vertical tows during daytime. In total, 25,819 ichthyoplankton samples were collected, of which 25,449 samples (i.e., 24,757 eggs and 692 larvae) were from horizontal tows. For horizontal tow samples, the ichthyoplankton were classified into 58 taxa in 15 orders and 23 families with a combination of external morphology and DNA barcoding analyses, from pelagic to demersal and benthic species. The dominant order was the Gobiiformes, including 23 species (39.7% of all species). The dominant taxa, in terms of relative abundance and frequency of occurrence, consisted of commercially important fishes, such as Setipinna tenuifilis (Valenciennes, 1848) (Engraulidae), Epinephelus akaara (Temminck and Schlegel, 1842) (Serraenidae), Collichthys lucidus (Richardson, 1844), Nibea albiflora (Richardson, 1846) (Sciaenidae), Acanthopagrus schlegelii (Bleeker, 1854), and Pagrus major (Temminck and Schlegel, 1843) (Sparidae), accounting for 78.9% of the horizontal tow samples. Low-valued and small-sized fishes, such as Stolephorus commersonnii Lacepède, 1803 (Engraulidae), Solea ovata Richardson, 1846 (Soleidae), Nuchequula nuchalis (Temminck and Schlegel, 1845), and Photopectoralis bindus (Valenciennes, 1835) (Leiognathidae), were also dominant species, accounting for 11.4% of the horizontal tow samples. The ichthyoplankton assemblage was categorized into five different temporal assemblages based on the cluster and nonmetric multidimensional scaling analysis, namely, April, May, June, July, and August−September (ANOSIM, Global R = 0.656, p < 0.01) with the highest density and richness of ichthyoplankton occurred in May. The spatial distribution pattern showed that the high density (ind./m 3 ) of ichthyoplankton occurred mainly in S12–S25 in Guanjingyang and along the Dongchong Peninsula coastline into Dongwuyang, while low density occurred mainly in S01–S11 in the northwest waters of Sandu Island (ANOVA, F = 8.270, p < 0.05). Temperature, salinity, and chlorophyll a were key factors structuring the ichthyoplankton assemblages in Sansha Bay. In addition, this study revealed the changes of the ichthyoplankton composition, density, and spatial distribution in Sansha Bay over the past three decades.

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Molecular characterization and gene expression analysis of tomato WOX transcription factor family under abiotic stress and phytohormone treatment - Hui Li; Xiaohong Li; Meihua Sun; Shuisen Chen; Hui Ma; Jingwei Lin; Yibo Sun; Ming Zhong (Journal of Plant Biochemistry and Biotechnology, 2021)

Intramyocardial injection of human adipose-derived stem cells ameliorates cognitive deficit by regulating oxidative stress–mediated hippocampal damage after myocardial infarction - Tsung-Ming LEE; Cheng-Che LEE; Horng-Jyh HARN; Tzyy-Wen Chiou; Ming-Hsi CHUANG; Chun-Hung CHEN; Chi-Hsuan CHUANG; Po-Cheng LIN; Shinn-Zong LIN (Journal of Molecular Medicine, 2021)
Cognitive impairment is a serious side effect of post-myocardial infarction (MI) course. We have recently demonstrated that human adipose-derived stem cells (hADSCs) ameliorated myocardial injury after MI by attenuating reactive oxygen species (ROS) levels. Here, we studied whether the beneficial effects of intramyocardial hADSC transplantation can extend to the brain and how they may attenuate cognitive dysfunction via modulating ROS after MI. After coronary ligation, male Wistar rats were randomized via an intramyocardial route to receive either vehicle, hADSC transplantation (1 × 10 6 cells), or the combination of hADSCs and 3-Morpholinosydnonimine (SIN-1, a peroxynitrite donor). Whether hADSCs migrated into the hippocampus was assessed by using human-specific primers in qPCR reactions. Passive avoidance test was used to assess cognitive performance. Postinfarction was associated with increased oxidative stress in the myocardium, circulation, and hippocampus. This was coupled with decreased numbers of dendritic spines as well as a significant downregulation of synaptic plasticity consisting of synaptophysin and PSD95. Step-through latency during passive avoidance test was impaired in vehicle-treated rats after MI. Intramyocardial hADSC injection exerted therapeutic benefits in improving cardiac function and cognitive impairment. None of hADSCs was detected in rat’s hippocampus at the 3rd day after intramyocardial injection. The beneficial effects of hADSCs on MI-induced histological and cognitive changes were abolished after adding SIN-1. MI-induced ROS attacked the hippocampus to induce neurodegeneration, resulting in cognitive deficit. The remotely intramyocardial administration of hADSCs has the capacity of improved synaptic neuroplasticity in the hippocampus mediated by ROS, not the cell engraftment, after MI. Key messages Human adipose-derived stem cells (hADSCs) ameliorated injury after myocardial infarction by attenuating reactive oxygen species (ROS) levels. Intramyocardial administration of hADSCs remotely exerted therapeutic benefits in improving cognitive impairment after myocardial infarction. The improved synaptic neuroplasticity in the hippocampus was mediated by hADSC-inhibiting ROS, not by the stem cell engraftment.

Association between exposure to road traffic noise and hearing impairment: a case-control study - Tang-Chuan Wang; Ta-Yuan Chang; Richard S. Tyler; Bing-Fang Hwang; Yi-Hung Chen; Che-Ming Wu; Chiu-Shong Liu; Kuang-Chao Chen; Chia-Der Lin; Ming-Hsui Tsai (Journal of Environmental Health Science and Engineering, 2021)

Expression profiling of WRKY transcription factors in Spinach - Yaying Ma; Shuai Chen; Hongying Yu; Ruoyu Li; Zhicong Lin; Mingxing Cai; Min Tang; Xingtan Zhang; Ray Ming (Euphytica, 2021)

Experimental study on the discharge characteristics of viscous debris flow with grid-type dam - Jinfeng Liu; Dong Yuan; Ming Lu; Yong You; Guangze Zhang; Tao Feng; Dong Wang; Zhiheng Lin (Environmental Fluid Mechanics, 2021)

Bioinformatics-based study to identify immune infiltration and inflammatory-related hub genes as biomarkers for the treatment of rheumatoid arthritis - Sheng Fang; Xin Xu; Lin Zhong; An-quan Wang; Wei-lu Gao; Ming Lu; Zong-Sheng Yin (Immunogenetics, 2021)

The r-X1 deletion induces terminal deficiencies in the maize B chromosome - Yen-Hua Huang; Tzu-Che Lin; Wan-Yi Chiou; Ya-Ming Cheng (Chromosome Research, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Interception, degradation and contributions of terrestrial organic carbon obtained from lignin analysis in Wujiang River, southwest China - Xin Lin; Yujie Wang; Jinhua Zhang; Ming Yang; Xueping Chen; Fushun Wang; Jing Ma (Acta Geochimica, 2021)

Timing and magnitude of climatic extremes differentially elevate mortality but enhance recovery in a fish population - Ming‐Chih Chiu; Shih‐Hsun Chang; Yu‐Ting Yen; Lin‐Yan Liao; Hsing‐Juh Lin (Global Change Biology, 2021)
The countervailing effects of disturbances (e.g., high mortality and enhanced recovery) on population dynamics can occur through demographic processes under rapidly increasing climatic extremes. Across an extreme‐event gradient, we mechanistically demonstrated how dramatic changes in streamflow have affected the population persistence of endangered salmon in monsoonal Taiwan over a three‐decade period. Our modeling indicated that the dynamics of the age‐structured population were attributed to demographic processes, in which extensive mortality was characterized as a function of climatic extremes and vulnerability in the young stage of fish. In the stochastic simulations, we found that the extensive mortality and high proportion of large fish resulted from extreme flooding, which caused high values of postimpact population recovery. Our empirical evidence suggests that the magnitudes and timing of disturbance can explain the population persistence when facing climatic extremes and thereby challenges the understanding of the mechanistic drivers of these countervailing phenomena under changing environmental conditions.

Identification and antimicrobial properties of a new alkaloid produced by marine-derived Verrucosispora sp. FIM06-0036 - Ming-Hong Chen; Yun-Yang Lian; Dong-Sheng Fang; Li Chen; Jia Jia; Wen-Long Zhang; Ru Lin; Yang Xie; Hong-Kai Bi; Hong Jiang (Natural Product Research, 2021)

Numerical Simulation of the Time-Dependent Mild-Slope Equation by the Generalized Finite Difference Method - Ting Zhang; Zhen-Huan Lin; Chuan Lin; Lin Liang; Chia-Ming Fan (Pure and Applied Geophysics, 2021)

Dopaminergic Projection from Ventral Tegmental Area to Substantia Nigra Pars Reticulata Mediates Chronic Social Defeat Stress–Induced Hypolocomotion - Feng He; Pei Zhang; Qian Zhang; Guangjian Qi; Hongwei Cai; Tongxia Li; Ming Li; Jiazhen Lu; Jiaen Lin; Jie Ming; Bo Tian (Molecular Neurobiology, 2021)

Geo-structures and deformation-failure characteristics of rockslide areas near the Baige landslide scar in the Jinsha River tectonic suture zone - Shi-lin Zhang; Yue-ping Yin; Xie-wen Hu; Wen-pei Wang; Zong-liang Li; Xin-ming Wu; Gang Luo; Sai-nan Zhu (Landslides, 2021)

Development and validation of gene-specific KASP markers for YrAS2388R conferring stripe rust resistance in wheat - Yanling Hu; Xuhui Huang; Fang Wang; Yu He; Lihua Feng; Bo Jiang; Ming Hao; Shunzong Ning; Zhongwei Yuan; Jiajie Wu; Lianquan Zhang; Bihua Wu; et al. (Euphytica, 2021)

Streptomyces luteolifulvus sp. nov., a novel actinomycete isolated from soil in Nanjing, China - Shanshan Zhao; Ming Cheng; Congyu Lin; He Liu; Zhengran Wang; Kai Zhang; Simin Song; Qian Yang (Antonie van Leeuwenhoek, 2021)

Pseudomonas nanhaiensis sp. nov., a lipase-producing bacterium isolated from deep-sea sediment of the South China Sea - Yu Pang; Yage Zhang; Mengru Chen; Wei Lu; Ming Chen; Yongliang Yan; Min Lin; Wei Zhang; Zhengfu Zhou (Antonie van Leeuwenhoek, 2021)

Identification of plant materials containing ephedrine alkaloids based on DNA barcoding and TaqMan real-time PCR assay - Yaqin Zheng; Han Gao; Ming Song; Yunhan Lin; Jiajia Fan; Yaqin Zhang; Xia Liu (Acta Physiologiae Plantarum, 2021)
An intentional or inadvertent mixing of plant materials containing ephedrine alkaloids, especially Ephedra , is illegal. In order to better detect plant materials containing ephedrine alkaloids in export and smuggling, DNA barcoding combined with a TaqMan real-time PCR-based assay were used in this study. We collected 201 samples from 18 species belonging to four genera distributed in three families to amplify two barcoding markers, internal transcribed spacer 2 (ITS2) and psb A -trn H. 175 ITS2 sequences and 136 psb A- trn H sequences were obtained. Alignments and the neighbor-joining tree indicated that ITS2 showed a better discrimination of species than psb A -trn H. In addition, based on the sequence comparison of the ITS2 region from 18 species, three sets of primer/probes were designed using the real-time PCR assay platform. A sensitivity test showed the above primer/probe sets were specific and sensitive (as little as 0.0050 ng/μL target DNA) to identify species containing ephedrine alkaloids. Hence, the combination of novel DNA barcoding and the TaqMan real-time PCR-based technique are promising tools for the identification of plant materials containing ephedrine alkaloids. It is beneficial to standardize market circulation and detection of plant materials containing ephedrine alkaloids.

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Investigation and disinfection of bacteria and fungi in sports fitness center - Nonglak Boonrattanakij; Sirikorn Yomchinda; Fang-Jia Lin; Luzvisminda M. Bellotindos; Ming-Chun Lu (Environmental Science and Pollution Research, 2021)

Damage mechanism of tunnels in the high-content salt rock stratum - Ping Zhou; Jinyi Li; Yifan Jiang; Feicong Zhou; Ming Lin; Jiayong Lin; Zhijie Wang (Bulletin of Engineering Geology and the Environment, 2021)

Shared and specific patterns of structural and functional thalamo-frontal disturbances in manic and euthymic pediatric bipolar disorder - Yi-Bing Guo; Wei-Jia Gao; Zhi-Liang Long; Wei-Fang Cao; Dong Cui; Yong-Xin Guo; Qing Jiao; Jian-Feng Qiu; Lin-Yan Su; Guang-Ming Lu (Brain Imaging and Behavior, 2021)
Bipolar disorder (BD) is clinically defined by alternating depressive and manic episodes with a separated period of euthymia. Thalamo-frontal loop plays vital role in psychotic symptoms, altered motor control and executive difficulties in BD. It remains unclear that structural and functional alterations of thalamo-frontal loop among the different mood states in BD, especially in pediatric BD(PBD). Twenty manic PBD (mPBD), 20 euthymic PBD (ePBD) and 19 healthy controls (HCs) were included in the study. By analyzing the T1 images and fMRI signals, thalamus volume and frontal grey matter cortical thickness were tested, and functional connectivity (FC) between bilateral thalamus and frontal cortex was calculated. Relationship between clinical indices and thalamo-frontal FC was also evaluated in mPBD and ePBD adolescents. Compared to HCs, the cortical thickness of left middle frontal gyrus (MFG), bilateral superior frontal gyrus (SFG) was significantly decreased in both mPBD and ePBD patients, and volume of left thalamus and cortical thickness of right MFG significantly decreased in mPBD patients. Compared to that of the HCs and ePBD subjects, thalamo-frontal hyperconnectivity with MFG was found in mPBD, and compared with that of HCs, thalamo-frontal hypoconnectivity with precentral gyrus/SFG was found in ePBD. In ePBD patients, episode times positively correlated with FC values between thalamus and precentral gyrus. The findings of the present study demonstrate detailed knowledge regarding shared and specific structural and functional disruption in thalamo-frontal loop in mPBD and ePBD subjects. Thalamo-frontal abnormalities reported in adult BD subjects were also observed in adolescent BD patients, and thalamo-frontal dysfunction may be a crucial treatment target in BD.

Resveratrol Mitigates Cerebral Ischemic Injury by Altering Levels of Trace Elements, Toxic Metal, Lipid Peroxidation, and Antioxidant Activity - Ju-Hai Ro; Chien-Chi Liu; Ming-Cheng Lin (Biological Trace Element Research, 2021)

Scleractinian diversity in the upper mesophotic zone of Ludao (Taiwan): a museum collection with new records from Taiwanese waters - Stéphane De Palmas; Vianney Denis; Derek Soto; Yuting Vicky Lin; Ming-Jay Ho; Chaolun Allen Chen (Marine Biodiversity, 2021)

Sandaracinobacteroides hominis gen. nov., sp. nov., isolated from human skin - Ping-Hua Qu; Hai-Min Luo; Jun-Hui Feng; Song Li; Cha Chen; Lei Dong; Yu-Zhen Ming; Wen-Jun Li; Ying Lin (Archives of Microbiology, 2021)

A new monoterpene-lactone with neuroprotective activity from corn silk - Wei-Yu Zhou; Tian-Ming Lv; Zi-Lin Hou; Ming Bai; Bin Lin; Xiao-Xiao Huang; Shao-Jiang Song (Natural Product Research, 2021)

Identification of a recessive gene YrZ15-1370 conferring adult plant resistance to stripe rust in wheat-Triticum boeoticum introgression line - Minghu Zhang; Xin Liu; Ting Peng; Dinghao Wang; Dongyu Liang; Hongyu Li; Ming Hao; Shunzong Ning; Zhongwei Yuan; Bo Jiang; Xuejiao Chen; Xue Chen; et al. (Theoretical and Applied Genetics, 2021)

The ATP Level in the mPFC Mediates the Antidepressant Effect of Calorie Restriction - Qian Wang; Ying Kong; Song Lin; Ding-Yu Wu; Jian Hu; Lang Huang; Wen-Si Zang; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson’s disease: a systematic review and meta-analysis - De-Qi Jiang; Qing-Min Zang; Li-Lin Jiang; Yan Wang; Ming-Xing Li; Jing-Yi Qiao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice - Thomas H Lee; Ahadullah; Brian R Christie; Kangguang Lin; Parco Ming-fai Siu; Li Zhang; Ti-fei Yuan; Pragya Komal; Aimin Xu; Kwok-fai So; Suk-yu Yau (Molecular Neurobiology, 2021)
Administration of exercise mimetic drugs could be a novel therapeutic approach to combat comorbid neurodegeneration and metabolic syndromes. Adiponectin is an adipocyte-secreted hormone. In addition to its antidiabetic effect, adiponectin mediates the antidepressant effect of physical exercise associated with adult hippocampal neurogenesis. The antidiabetic effect of the adiponectin receptor agonist AdipoRon has been demonstrated, but its potential pro-cognitive and neurotrophic effects in the hippocampus under diabetic condition are still unclear. This study reported that chronic AdipoRon treatment for 2 weeks improved hippocampal-dependent spatial recognition memory in streptozotocin-induced diabetic mice. Besides, AdipoRon treatment increased progenitor cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (DG) of diabetic mice. Furthermore, AdipoRon treatment significantly increased dendritic complexity, spine density, and N -methyl-D-aspartate receptor-dependent long-term potentiation (LTP) in the dentate region, and increased BDNF levels in the DG of diabetic mice. AdipoRon treatment activated AMPK/PGC-1α signalling in the DG, whereas increases in cell proliferation and LTP were not observed when PGC-1α signalling was pharmacologically inhibited. In sum, chronic AdipoRon treatment partially mimics the benefits of physical exercise for learning and memory and hippocampal neuroplasticity in the diabetic brain. The results suggested that AdipoRon could be a potential physical exercise mimetic to improve hippocampal plasticity and hence rescue learning and memory impairment typically associated with diabetes.

Non-coding RNA: insights into the mechanism of methamphetamine neurotoxicity - Ying-Jian Gu; Lei Chen; Lin Cheng; Ming-Yuan Zhou; Yun Wang (Molecular and Cellular Biochemistry, 2021)

Flavobacterium difficile sp. nov., isolated from a freshwater waterfall - Wen-Ming Chen; Ya-Xiu You; Chiu-Chung Young; Shih-Yao Lin; Shih-Yi Sheu (Archives of Microbiology, 2021)

Anti-Inflammatory and anti-proliferative oleanane-type triterpene glycosides from the vine of Momordica cochinchinensis - Hung-Tse Huang; Yu-Chi Lin; Li-Jie Zhang; Chia-Ching Liaw; Hsin-Yen Chen; Ming-Tung Hsueh; Yao-Haur Kuo (Natural Product Research, 2021)

Prediction of Metabolic Disorders Using NMR-Based Metabolomics: The Shanghai Changfeng Study - Qi Wu; Qing-xia Huang; Hai-luan Zeng; Shuai Ma; Huan-dong Lin; Ming-feng Xia; Hui-ru Tang; Xin Gao (Phenomics, 2021)

Synthesis and biological evaluation of novel 1,3-diphenylurea quinoxaline derivatives as potent anticancer agents - Gui-Zhen Li; Xi-Lin Ouyang; Zu-Yu Mo; Yao Gu; Xiao-Lin Cao; Li Yang; Hai-Tao Tang; Ying-Ming Pan (Medicinal Chemistry Research, 2021)

Patient Confidential Information Transmission Using the Integration of PSO-Based Biomedical Signal Steganography and Threshold-Based Compression - Shih-Ying Chen; Shan-Ju Lin; Ming-Cheng Tsai; Ming-Dar Tsai; Yih-Jing Tang; Shuo-Tsung Chen; Li-Hsiang Wang (Journal of Medical and Biological Engineering, 2021)

Risk of two common glandular cell-type cancers (breast and colorectal cancers) in Chinese occupational chefs: a nationwide ecological study in Taiwan - Pei-Chen Lin; Chiung‑Yu Peng; Chih‑Hong Pan; Jui-Ying Lee; Tusty-Jiuan Hsieh; Yun-Shiuan Chuang; Robert J. Turesky; Chia-Fang Wu; Ming-Tsang Wu (International Archives of Occupational and Environmental Health, 2021)

Gas-phase isopropanol degradation by nonthermal plasma combined with Mn-Cu/-Al2O3 - Ken-Lin Chang; Yu-Chieh Lin; Ming-Ze Qiu; Chun-Wei Tu; Chih-Ping Chang; Jhong-Lin Wu; Yung-Chang Lin; Chien-Kuei Chang (Environmental Science and Pollution Research, 2021)

Nanotechnology advances in pathogen- and host-targeted antiviral delivery: multipronged therapeutic intervention for pandemic control - Kai-Chieh Yang; Jung-Chen Lin; Hsiao-Han Tsai; Chung-Yao Hsu; Vicky Shih; Che-Ming Jack Hu (Drug Delivery and Translational Research, 2021)

Spontaneous thought-related network connectivity predicts sertraline effect on major depressive disorder - Li-Ming Hsu; Timothy Joseph Lane; Changwei W. Wu; Chien-Yuan Lin; Chi-Bin Yeh; Hung-Wen Kao; Ching-Po Lin (Brain Imaging and Behavior, 2021)

Efficacy of Entomopathogenic fungus Aspergillus nomius against Dolichoderus thoracicus - Wei-Jiun Lin; Ming-Chung Chiu; Chung-Chi Lin; Yuan-Kai Chung; Jui-Yu Chou (BioControl, 2021)

Effects of diethyl aminoethyl hexanoate on the physiology and selenium absorption of grape seedlings - Lei Liu; Jiaxi Han; Lili Deng; Huixuan Zhou; Yuhui Bie; Qianhe Jing; Lijin Lin; Jin Wang; Ming’an Liao (Acta Physiologiae Plantarum, 2021)

The developmental regulator PatD modulates assembly of the cell‐division protein FtsZ in the cyanobacterium Anabaena sp. PCC 7120 - Li Wang; Tian‐Cai Niu; Ana Valladares; Gui‐Ming Lin; Ju‐Yuan Zhang; Antonia Herrero; Wen‐Li Chen; Cheng‐Cai Zhang (Environmental Microbiology, 2021)
Summary FtsZ is a tubulin‐like GTPase that polymerizes to initiate the process of cell division in bacteria. Heterocysts are terminally differentiated cells of filamentous cyanobacteria that have lost the capacity for cell division and in which the ftsZ gene is downregulated. However, mechanisms of FtsZ regulation during heterocyst differentiation have been scarcely investigated. The patD gene is NtcA dependent and involved in the optimization of heterocyst frequency in Anabaena sp. PCC 7120. Here, we report that the inactivation of patD caused the formation of multiple FtsZ‐rings in vegetative cells, cell enlargement, and the retention of peptidoglycan synthesis activity in heterocysts, whereas its ectopic expression resulted in aberrant FtsZ polymerization and cell division. PatD interacted with FtsZ, increased FtsZ precipitation in sedimentation assays, and promoted the formation of thick straight FtsZ bundles that differ from the toroidal aggregates formed by FtsZ alone. These results suggest that in the differentiating heterocysts, PatD interferes with the assembly of FtsZ. We propose that in Anabaena FtsZ is a bifunctional protein involved in both vegetative cell division and regulation of heterocyst differentiation. In the differentiating cells PatD‐FtsZ interactions appear to set an FtsZ activity that is insufficient for cell division but optimal to foster differentiation.

Prenylated xanthones and biphenyls from Garcinia esculenta with antistaphylococcal activity - Dan Zheng; Hong Zhang; Jia-Ming Jiang; Yu-Yu Chen; Shi-Jie Wan; Zhi-Xiu Lin; Hong-Xi Xu (Natural Product Research, 2021)

A preliminary investigation of epibiotic macrofauna on the mangrove horseshoe crab Carcinoscorpius rotundicauda (Latreille, 1802) in Singapore - LIM Chin Sing; TAN Lester Jin Xiang; NEO Mei Lin; TEO Serena Lay Ming; BENG Stephen Sui Leung; NADARAJAN Saravanan; TUN Karenne (Marine Biology Research, 2021)

Strong in vitro and in vivo cytotoxic effects of two platinum(II) complexes with cryptolepine derivatives - Li-Qin Qin; Zu-Zhuang Wei; Lin Yang; Qi-Pin Qin; Jia-Jing Zeng; Ming-Xiong Tan; Hong Liang (Medicinal Chemistry Research, 2021)

A luminescent Zn(II)-Containing Complex: Selective Sensing of Cr(VI) Anion and Application Values on Tuberculosis Care Through Increasing the Antibacterial Response of Macrophages - Jin-Chao Mao; Jin-Jing Hong; Ming-Zheng Lin; Feng Han; Dong Li (Journal of Fluorescence, 2021)

Effect of water regime and harvest stage on essential oil accumulation in basil plant growing in sandy soil - João V. R. S. Souza; Lin Chau Ming; Marcos A. L. Santos; James E. Simon; Hector R. Juliani; João C. C. Saad (Irrigation Science, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

The mechanism and application of high-pressure water jet technology to prevent compound dynamic disaster - Zeng-qiang Yang; Chang Liu; Feng-shuo Li; Lin-ming Dou; Gang-wei Li; Da-wei Wang (Arabian Journal of Geosciences, 2021)

Effects of mutual grafting Solanum photeinocarpum from two ecosystems on physiology and selenium absorption of their offspring under selenium stress - Kewen Huang; Yan Wang; Xiaohan Wei; Yuhui Bie; Huixuan Zhou; Lili Deng; Lijin Lin; Ming’an Liao (Acta Physiologiae Plantarum, 2021)

In-Situ Seawater Gamma Spectrometry with LaBr3 Detector at a Nuclear Power Plant Outlet - Daowei Dou; Zhi Zeng; Wen Yu; Ming Zeng; Wu Men; Feng Lin; Hao Ma; Jianping Cheng; Junli Li (Journal of Marine Science and Engineering, 2021)
In a nuclear emergency, the application of in situ spectrometers for monitoring environmental radioactivity is significantly important, as information on the type and activity of radionuclides released from the accident can be obtained quickly. However, in emergency environmental radiological monitoring, a balance between energy resolution and detecting efficiency must be considered in selecting an appropriate detector. In this study, in situ gamma spectrometry was conducted with the LaBr3 detector to determine the radioactivity of seawater at the discharging outlet of a coastal nuclear power plant in southeast China. The results show that the LaBr3 scintillator has excellent energy resolution and detection efficiency, making it a promising detector for emergency monitoring.

Flavonoids from Artemisia rupestris and their synergistic antibacterial effects on drug-resistant Staphylococcus aureus - Jiang-Er Lan; Xiao-Jin Li; Xiao-Feng Zhu; Zhong-Lin Sun; Jian-Ming He; Mire Zloh; Simon Gibbons; Qing Mu (Natural Product Research, 2021)

Correction to: Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain - Shao-Ming Wang; Nino Goguadze; Yuriko Kimura; Yuko Yasui; Bin Pan; Tzu-Yun Wang; Yoki Nakamura; Yu-Ting Lin; Quinn H. Hogan; Katherine L. Wilson; Tsung-Ping Su; Hsiang-en Wu (Molecular Neurobiology, 2021)
A correction to this paper has been published: 10.1007/s12035-021-02310-3

Different posterior hippocampus and default mode network modulation in young APOE ε4 carriers: a functional connectome-informed phenotype longitudinal study - Li Juan Zheng; Li Lin; U. Joseph Schoepf; Akos Varga-Szemes; Rock H. Savage; Han Zhang; Yun Fei Wang; Xin Yuan Zhang; Song Luo; Ya Liu; Gui Fen Yang; Guang Ming Lu; et al. (Molecular Neurobiology, 2021)

Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain - Shao-Ming Wang; Nino Goguadze; Yuriko Kimura; Yuko Yasui; Bin Pan; Tzu-Yun Wang; Yoki Nakamura; Yu-Ting Lin; Quinn H. Hogan; Katherine L. Wilson; Tsung-Ping Su; Hsiang-en Wu (Molecular Neurobiology, 2021)
Sigma-1 receptors (Sig-1Rs) are endoplasmic reticulum (ER) chaperones implicated in neuropathic pain. Here we examine if the Sig-1R may relate to neuropathic pain at the level of dorsal root ganglia (DRG). We focus on the neuronal excitability of DRG in a “spare nerve injury” (SNI) model of neuropathic pain in rats and find that Sig-1Rs likely contribute to the genesis of DRG neuronal excitability by decreasing the protein level of voltage-gated Cav2.2 as a translational inhibitor of mRNA. Specifically, during SNI, Sig-1Rs translocate from ER to the nuclear envelope via a trafficking protein Sec61β. At the nucleus, the Sig-1R interacts with cFos and binds to the promoter of 4E-BP1, leading to an upregulation of 4E-BP1 that binds and prevents eIF4E from initiating the mRNA translation for Cav2.2. Interestingly, in Sig-1R knockout HEK cells, Cav2.2 is upregulated. In accordance with those findings, we find that intra-DRG injection of Sig-1R agonist (+)pentazocine increases frequency of action potentials via regulation of voltage-gated Ca2+ channels. Conversely, intra-DRG injection of Sig-1R antagonist BD1047 attenuates neuropathic pain. Hence, we discover that the Sig-1R chaperone causes neuropathic pain indirectly as a translational inhibitor.

Molecular Imaging for Radiolabeling a PSMA-Targeted Long Circulating Peptide as a Theranostic Agent in Mice Bearing a Human Prostate Tumor - Ming-Hsin Li; Sheng-Nan Lo; Ming-Wei Chen; Wei-Lin Lo; Yuan-Ruei Huang; Shih-Ying Lee; Su-Jung Chen; Shih-Wei Lo; Shih-Ming Wang; Chih-Hsien Chang (Journal of Medical and Biological Engineering, 2021)

Environmental microorganism classification using optimized deep learning model - Chih-Ming Liang; Chun-Chi Lai; Szu-Hong Wang; Yu-Hao Lin (Environmental Science and Pollution Research, 2021)

Performance of permeable pavement systems on stormwater permeability and pollutant removal - Zhiji Yu; Huihui Gan; Ming Xiao; Biao Huang; David Z. Zhu; Zheyun Zhang; Huanyan Wang; Yongliang Lin; Yonglong Hou; Shuai Peng; Wei Zhang (Environmental Science and Pollution Research, 2021)

Icaritin Inhibits Skin Fibrosis through Regulating AMPK and Wnt/β-catenin Signaling - Ming Li; Qingmei Liu; Shan He; Xiangzhen Kong; Jinpei Lin; Yan Huang; Wenyu Wu; Jinfeng Wu (Cell Biochemistry and Biophysics, 2021)

Proton Pump Inhibitor Exposure and Acute Myocardial Infarction Risk: A Nested Cohort Study - Hsiang-Jung Tseng; Chih-Ming Cheng; Shih-Jen Tsai; Wei-Chen Lin; Ya-Mei Bai; Chia-Fen Tsai; Tung-Ping Su; Cheng-Ta Li; Tzeng-Ji Chen; Mu-Hong Chen (Cardiovascular Toxicology, 2021)

Computed Tomography Super-Resolution Using a Generative Adversarial Network in Bronchoscopy: A Clinical Feasibility Study - Heng-sheng Chao; Tsu-Hui Shiao; Chung-Wei Chou; Fang-Chi Lin; Yu-Te Wu; Der-Ming Liou (Journal of Medical and Biological Engineering, 2021)

Effects of Sediment Characteristics on Carbon Dioxide Fluxes Based on Interacting Factors in Unvegetated Tidal Flats - Wei-Jen Lin; Ming-Chih Chiu; Chiao-Wen Lin; Hsing-Juh Lin (Frontiers in Marine Science, 2021)
The contribution of unvegetated tidal flats to global net primary production is comparable to that of some vegetated coastal habitats. However, compared to carbon flux regulating factors in vegetated habitats, those in unvegetated tidal flats are not well understood, particularly in terms of their cause-effect relationships. Maximum gross primary production (GPP m ), net primary production (NPP) and total respiration (TR) during emersion at noon when the irradiance level was at the saturation level for photosynthesis in nine unvegetated tidal flats across the Taiwan Strait in tropical and subtropical regions were determined in winter and summer from 2011 to 2016 to examine the direct and indirect relationships between sediment characteristics and carbon fluxes by using structural equation models (SEM). Most of the GPP m and NPP values were higher in winter than in summer. Conversely, the TR values were higher in summer than in winter. The NPP values at some sites shifted to negative values in summer, indicating the sites were carbon sources. The values of GPP m , TR and NPP for the tidal flats all increased significantly with increasing sediment mud content. The SEM results showed that the sediment mud content directly increased GPP m or indirectly increased GPP m via a compositional shift in benthic microalgae. The sediment mud content also directly increased TR or indirectly increased TR via increased organic matter content. The contribution of benthic microalgal and macrofaunal biomass to TR was relatively minor. This result suggests that primary production was stimulated mainly by the organic matter content rather than by increased microalgal biomass. With the integrated SEM framework, our results showed mechanistic evidence of how sediment mud content acted as a critical factor regulating carbon fluxes in unvegetated tidal flats.

Emission sources and full spectrum of health impacts of black carbon associated polycyclic aromatic hydrocarbons (PAHs) in urban environment: A review - Muhammad Ubaid Ali; Lin Siyi; Balal Yousaf; Qumber Abbas; Rashida Hameed; Chunmiao Zheng; Xingxing Kuang; Ming Hung Wong (Critical Reviews in Environmental Science and Technology, 2021)

Study on Microwave Heating Order and Electromagnetic Characteristics of Copper and Gold Ores - Feng Lin; Xia-Ting Feng; Gao-Ming Lu; Xiang-Xin Su; Shi-Ping Li; Jiu-yu Zhang (Rock Mechanics and Rock Engineering, 2021)

QTL mapping of the genetic basis of stem diameter in soybean - Chong-Yuan Sun; Yu-Ming Yang; Lin Jia; Xiao-Qian Liu; Huan-Qing Xu; Hai-Yan Lv; Zhong-Wen Huang; Dan Zhang (Planta, 2021)

Amygdala-based Functional Network Reveals Dissociated Neural Correlates of Consensual and Idiosyncratic Emotional Movie Experiences - Lin Cui; Bingbing Guo; Dan Zhao; Jiaxin Li; Yu Luo; Ming Meng (Neuroscience Bulletin, 2021)

A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study - Nabeel A. Abdul-Rida; Ali M. Farhan; Najim A. Al-Masoudi; Bahjat A. Saeed; Dannah Miller; Ming-Fong Lin (Molecular Diversity, 2021)

Targeted deletion of HAI-1 increases prostasin proteolysis but decreases matriptase proteolysis in human keratinocytes - Dajun D. Lu; Yayun Gu; Sheng-Wen A. Li; Robert J. Barndt; Shih-Ming Huang; Jehng-Kang Wang; Hui Chen Su; Michael D. Johnson; Chen-Yong Lin (Human Cell, 2021)

Effects of indole acetic acid on the growth and selenium absorption characteristics of Cyphomandra betacea seedlings - Yunmin Huan; Liu Yang; Qin Liu; Lijin Lin; Ming’an Liao; Zhihui Wang; Dong Liang; Hui Xia; Yi Tang; Xiulan Lv; Jin Wang (Acta Physiologiae Plantarum, 2021)

Sepsis and Cerebral Dysfunction: BBB Damage, Neuroinflammation, Oxidative Stress, Apoptosis and Autophagy as Key Mediators and the Potential Therapeutic Approaches - Ming Gu; Xiang-Lin Mei; Ya-Nan Zhao (Neurotoxicity Research, 2021)

TLR8 in the Trigeminal Ganglion Contributes to the Maintenance of Trigeminal Neuropathic Pain in Mice - Lin-Xia Zhao; Ming Jiang; Xue-Qiang Bai; De-Li Cao; Xiao-Bo Wu; Jing Zhang; Jian-Shuang Guo; Tong-Tong Chen; Juan Wang; Hao Wu; Yong-Jing Gao; Zhi-Jun Zhang (Neuroscience Bulletin, 2021)
Trigeminal neuropathic pain (TNP) is a significant health problem but the involved mechanism has not been completely elucidated. Toll-like receptors (TLRs) have recently been demonstrated to be expressed in the dorsal root ganglion and involved in chronic pain. Here, we show that TLR8 was persistently increased in the trigeminal ganglion (TG) neurons in model of TNP induced by partial infraorbital nerve ligation (pIONL). In addition, deletion or knockdown of Tlr8 in the TG attenuated pIONL-induced mechanical allodynia, reduced the activation of ERK and p38-MAPK, and decreased the expression of pro-inflammatory cytokines in the TG. Furthermore, intra-TG injection of the TLR8 agonist VTX-2337 induced pain hypersensitivity. VTX-2337 also increased the intracellular Ca 2+ concentration, induced the activation of ERK and p38, and increased the expression of pro-inflammatory cytokines in the TG. These data indicate that TLR8 contributes to the maintenance of TNP through increasing MAPK-mediated neuroinflammation. Targeting TLR8 signaling may be effective for the treatment of TNP.

ZEB1: New advances in fibrosis and cancer - Lin Cheng; Ming-Yuan Zhou; Ying-Jian Gu; Lei Chen; Yun Wang (Molecular and Cellular Biochemistry, 2021)

EEG-Based Anxious States Classification Using Affective BCI-Based Closed Neurofeedback System - Chao Chen; Xuecong Yu; Abdelkader Nasreddine Belkacem; Lin Lu; Penghai Li; Zufeng Zhang; Xiaotian Wang; Wenjun Tan; Qiang Gao; Duk Shin; Changming Wang; Sha Sha; et al. (Journal of Medical and Biological Engineering, 2021)

Genetic architecture of wild soybean (Glycine soja Sieb. and Zucc.) populations originating from different East Asian regions - Muhammad Amjad Nawaz; Xiao Lin; Ting-Fung Chan; Hon-Ming Lam; Faheem Shehzad Baloch; Muhammad Amjad Ali; Kirill S. Golokhvast; Seung Hwan Yang; Gyuhwa Chung (Genetic Resources and Crop Evolution, 2021)

Crenobacter intestini sp. nov., Isolated from the Intestinal Tract of Konosirus punctatus - Song-Biao Shi; Jia-Fa Wu; Li-Fang Yang; Ming-Guo Jiang; Cai-Mi Gao; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Marinobacter shengliensis subsp. alexandrii Subsp. Nov., Isolated from Cultivable Phycosphere Microbiota of Highly Toxic Dinoflagellate Alexandrium catenella LZT09 and Description of Marinobacter shengliensis Subsp. shengliensis Subsp. Nov - Xi Yang; Rong Xiang; Nurhezreen Md Iqbal; Yu-Han Duan; Xiao-Ai Zhang; Lei Wang; Lin-Zeng Yu; Jia-Zhou Li; Ming-Fei Sun; Qiao Yang; Chun-Tian Zheng; Shen-Quan Liao (Current Microbiology, 2021)

Carbon isotope variations of modern soils in the eastern margin of the Tibetan Plateau and their controlling factors - Lin Qi; Yan-song Qiao; Zong-xiu Liu; Sha-sha Peng; Yu Cheng; Yan Wang; Xu-jiao Zhang; Ming-zhong Tian; Shuai-bin Yang; Wen-bin Bai (Journal of Mountain Science, 2021)

Western North Pacific Tropical Cyclone Database Created by the China Meteorological Administration - Xiaoqin Lu; Hui Yu; Ming Ying; Bingke Zhao; Shuai Zhang; Limin Lin; Lina Bai; Rijin Wan (Advances in Atmospheric Sciences, 2021)
This paper describes the access to, and the content, characteristics, and potential applications of the tropical cyclone (TC) database that is maintained and actively developed by the China Meteorological Administration, with the aim of facilitating its use in scientific research and operational services. This database records data relating to all TCs that have passed through the western North Pacific (WNP) and South China Sea (SCS) since 1949. TC data collection has expanded over recent decades via continuous TC monitoring using remote sensing and specialized field detection techniques, allowing collation of a multi-source TC database for the WNP and SCS that covers a long period, with wide coverage and many observational elements. This database now comprises a wide variety of information related to TCs, such as historical or real-time locations (i.e., best track and landfall), intensity, dynamic and thermal structures, wind strengths, precipitation amounts, and frequency. This database will support ongoing research into the processes and patterns associated with TC climatic activity and TC forecasting.

A CONSTANS-LIKE gene of Nelumbo nucifera could promote potato tuberization - Dingding Cao; Zhongyuan Lin; Longyu Huang; Rebecca Njeri Damaris; Ming Li; Pingfang Yang (Planta, 2021)

The response to flooding of two overwintering rice stem borers likely accounts for their changing impacts - Guang-Hua Luo; Zhi-Xin Luo; Zhi-Ling Zhang; Yang Sun; Ming-Hong Lu; Zhao-Lin Shu; Zi-Hua Tian; Ary A. Hoffmann; Ji-Chao Fang (Journal of Pest Science, 2021)

Association of FMO3 rs1736557 polymorphism with clopidogrel response in Chinese patients with coronary artery disease - Kong-Xiang Zhu; Pei-Yuan Song; He-Li; Mu-Peng Li; Yin-xiao Du; Qi-lin Ma; Li-Ming Peng; Xiao-Ping Chen (European Journal of Clinical Pharmacology, 2021)

Disinfection efficiency of hospital infectious disease wards with chlorine dioxide and hypochlorous acid - Ming-Chun Lu; Po-Lin Chen; Da-Ji Huang; Chih-Kuo Liang; Ching-Shan Hsu; Wei-Ting Liu (Aerobiologia, 2021)

Phylogenetic and ion-response analyses reveal a relationship between gene expansion and functional divergence in the Ca2+/cation antiporter family in Angiosperms - Ye Zheng; Lin-Bo Wang; Shu-Feng Sun; Shi-Ying Liu; Ming-Jia Liu; Juan Lin (Plant Molecular Biology, 2021)

Changes in arthropod community but not plant quality benefit a specialist herbivore on plants under reduced water availability - Po-An Lin; Chia-Ming Liu; Jia-Ang Ou; Cheng-Han Sun; Wen-Po Chuang; Chuan-Kai Ho; Natsuko Kinoshita; Gary W. Felton (Oecologia, 2021)

Effects of body postures on the shear modulus of thoracolumbar fascia: a shear wave elastography study - Baizhen Chen; Chunlong Liu; Ming Lin; Weixin Deng; Zhijie Zhang (Medical & Biological Engineering & Computing, 2021)

Identification of contaminants as members of the Bacillus pumilus group and analysis of contamination sources in the cultivation of Pleurotus geesteranus mushrooms - Na Lu; Wei-Dong Yuan; You-Liang Wu; Ji-Ling Song; Lin Ma; Wei-Ke Wang; Jing Yan; Zai-Ming Chen; Qing Chen (Journal of Plant Pathology, 2021)

Modeling motor task activation from resting-state fMRI using machine learning in individual subjects - Chen Niu; Alexander D. Cohen; Xin Wen; Ziyi Chen; Pan Lin; Xin Liu; Bjoern H. Menze; Benedikt Wiestler; Yang Wang; Ming Zhang (Brain Imaging and Behavior, 2021)

Astrocyte-Derived Lactate Modulates the Passive Coping Response to Behavioral Challenge in Male Mice - Ya-Nan Yin; Jian Hu; Yi-Li Wei; Ze-Lin Li; Zhou-Cai Luo; Rui-Qi Wang; Ke-Xin Yang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Calcium-sensing receptor in the development and treatment of pulmonary hypertension - Ming-Yuan Zhou; Lin Cheng; Lei Chen; Ying-Jian Gu; Yun Wang (Molecular Biology Reports, 2021)

Risk of mental illness after the diagnosis of occupational injury or disease: a retrospective cohort study - Ming-Hung Lin; Ya-Lun Yang; Fung-Chung Sung; Chiu-Shong Liu; Chi-Hsuan Lung; Jong-Yi Wang (International Archives of Occupational and Environmental Health, 2021)

KASP markers to detect sub-chromosomal arm translocations between 6VS of Haynaldia villosa and 6AS of wheat - Shujie Zhang; Chaolan Fan; Jiangtao Luo; Lei Huang; Die Xie; Yazhou Li; Zhuo Chen; Bo Jiang; Shunzong Ning; Zhongwei Yuan; Lin Huang; Lianquan Zhang; et al. (Euphytica, 2021)

Phylogenetic analysis of infectious bronchitis virus circulating in southern China in 2016–2017 and evaluation of an attenuated strain as a vaccine candidate - Libin Chen; Bin Xiang; Yanfen Hong; Qian Li; Haoyun Du; Qiuyan Lin; Ming Liao; Tao Ren; Chenggang Xu (Archives of Virology, 2021)

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Complement Factor H Displays Opposite Expression Patterns Under Two Situations of Methamphetamine Administration: Acute Exposure and Chronic Dependence - Ming Lin; Jiamin Xu; Zhimin Liu; Liang Qin; Xiaodong Wang; Xiaoping Pu (Neuroscience Bulletin, 2020)

A review of the Chinese monotypic genus Melliodendron (Styracaceae), with a new synonym of M. xylocarpum - Xue-Hui Wu; Rui Zhang; Timothy M. A. Utteridge; Yu-Lin Liu; Guang-Yao Yang; Ming Tang (Kew Bulletin, 2020)

Superoxide dismutase 3 as an inflammatory suppressor in A549 cells infected with Mycoplasma pneumoniae - Jia-Yuan Jin; Ye Chen; Xing-You Wang; Chen-Ming Li; Wei-Lin Chen; Li Li (Journal of Biosciences, 2020)

Melatonin ameliorates spatial memory and motor deficits via preserving the integrity of cortical and hippocampal dendritic spine morphology in mice with neurotrauma - Xiao-Jing Lin; Ruoxu Liu; Chenyi Li; Xueqing Yi; Bo Fu; M. J. Walker; Xiao-Ming Xu; Gang Sun; Cheng-Hsien Lin (Inflammopharmacology, 2020)

Correction to: 4-Phenylbutyric acid protects against vasculitic peripheral neuropathy induced by ischaemia–reperfusion through attenuating endoplasmic reticulum stress - Cay‑Huyen Chen; Ping‑Chen Shih; Han‑Yu Lin; Po‑Kai Wang; Po‑Ting Pan; Ching‑Wei Chuang; Ming‑Chang Kao (Inflammopharmacology, 2020)

Seasonal succession of phytoplankton in two temperate artificial lakes with different water sources - Jing Wei; Min Wang; Chongtai Chen; Haiming Wu; Li Lin; Ming Li (Environmental Science and Pollution Research, 2020)

Using sowing date management to promote micronutrient quality and alleviate cadmium accumulation in rice grains - Lin-lin Shi; Ming-xing Shen; Hong-jun Wu; Chang-ying Lu; Li-juan Mei; Xin-lian Zhu; Hai-hou Wang; Yun-Sheng Song (Cereal Research Communications, 2020)

Gut dysbiosis-influence on amygdala-based functional activity in patients with end stage renal disease: a preliminary study - Li Juan Zheng; Li Lin; Jianhui Zhong; Zhihong Zhang; Yu Bing Ye; Xin Yuan Zhang; Yun Fei Wang; Han Zhang; Ya Liu; Guang Ming Lu; Dehua Gong; Long Jiang Zhang (Brain Imaging and Behavior, 2020)

Overexpression of a multifunctional β-glucosidase gene from thermophilic archaeon Sulfolobus solfataricus in transgenic tobacco could facilitate glucose release and its use as a reporter - Chih-Hao Huang; Tzu-Ling Huang; Yu-Chang Liu; Ting-Chieh Chen; Shih-Ming Lin; Shyh-Yu Shaw; Ching-Chun Chang (Transgenic Research, 2020)

Characteristics of fault structures in the south coastal zone of Taizhou based on aeromagnetic data - Ming Wang; Shengjun Liang; Jiaojiao Li; Xiaoxing Lin; Yongjun Zhang (Applied Geophysics, 2020)

Geochemical constraints on the origin of late Cenozoic basalts in the Mt. Changbai volcanic field, NE China: evidence for crustal recycling - Ming Lei; Zhengfu Guo; Yutao Sun; Maoliang Zhang; Lihong Zhang; Lin Ma (International Geology Review, 2020)

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

One-pot synthesis of substituted pyrrole–imidazole derivatives with anticancer activity - Ming Zhang; Yong Ding; Hong-Xia Qin; Zhi-Gang Xu; Hai-Tao Lan; Dong-Lin Yang; Cheng Yi (Molecular Diversity, 2020)

Two new species of Hortiboletus (Boletaceae, Boletales) from China - Hui-Jing Xie; Wen-Fei Lin; Shuai Jiang; Rou Xue; Lu-Ling Wu; Yu-Zhuo Zhang; Zhi-Qun Liang; Nian-Kai Zeng; Ming-Sheng Su (Mycological Progress, 2020)

Optimizing the MIC breakpoints of amoxicillin and tetracycline for antibiotic selection in the rescue therapy of H. pylori with bismuth quadruple regimen - Ming-Tsung Hsieh; Wei-Lun Chang; Chung-Tai Wu; Hsiao-Bai Yang; Hsin-Yu Kuo; Meng-Ying Lin; Hsiu-Chi Cheng; Yu-Chin Tsai; Bor-Shyang Sheu (European Journal of Clinical Pharmacology, 2020)

Effects of intercropping accumulator plants and applying their straw on the growth and cadmium accumulation of Brassica chinensis L. - Yi Tang; Liming Wang; Yongdong Xie; Xuena Yu; LiJin Lin; Huanxiu Li; Ming’an Liao; Zhihui Wang; Guochao Sun; Dong Liang; Hui Xia; Xun Wang; et al. (Environmental Science and Pollution Research, 2020)

Adaptive transgenerational effects remain significant - Yuan‐Ye Zhang; Junjie Yin; Ming Zhou; Zeru Lin; Qingshun Q. Li (Ecology Letters, 2020)
The comment by Sánchez‐Tójar et al . (2020, Ecol Lett) questioned the methodology, transparency and conclusion of our study (Ecol Lett, 22, 2019, 1976). The comment has overlooked important evolutionary assumptions in their reanalysis, and the issues raised were in fact dealt with through the peer‐review process. Far from being biased, the key conclusion of our meta‐analysis still stands; transgenerational effects are largely adaptive.

The Bearing Capacity Evaluations of a Spread Footing on Single Thick Stratum or Two-Layered Cohesive Soils - Chao-Ming Chi; Zheng-Shan Lin (Journal of Marine Science and Engineering, 2020)
Nowadays many countries plan to increase the percentages of renewable energies by developing offshore wind power. Due to the large sizes of offshore foundations, such as spudcan footings of jack-up barges or pile anchors of wind turbines, the affected soil depth range caused by the foundation under loading can be relatively deep, so the affected range may include a single thick layer or stratified soils. This paper utilizes limit analysis and FLAC numerical simulation to investigate the bearing capacity of a footing on single thick stratum or two-layered cohesive soils. Under nature deposition condition, the undrained shear strength of most cohesive soil approximately increases linearly as the depth increases. The closed-form upper bound solutions of fully rough or fully smooth footings on thick cohesive soils are provided, for the purpose of fast evaluations in practical engineering, and the outcomes are within the results from the FLAC simulation and slip circle method. The problems of punch-through shear failure or soil squeezing could be critical for two-layered soils under some conditions, and the associated bearing factors and the failure mechanisms from different methods are demonstrated and discussed in the article.

Intrusion of Kuroshio Helps to Diminish Coastal Hypoxia in the Coast of Northern South China Sea - Hon-Kit Lui; Chen-Tung Arthur Chen; Wei-Ping Hou; Jian-Ming Liau; Wen-Chen Chou; You-Lin Wang; Chau-Ron Wu; Jay Lee; Yi-Chia Hsin; Yan-Yu Choi (Frontiers in Marine Science, 2020)

One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko - Wan-Rong Niu; Cong-Liang Guo; Deng-Ji Lou; Rui-Ting Li; Qiao Xiang; Yu-Lin Zou; Xiu-Ming Cui; Xiao-Yan Yang (Natural Product Research, 2020)

Cerebral Organoids Repair Ischemic Stroke Brain Injury - Shu-Na Wang; Zhi Wang; Tian-Ying Xu; Ming-He Cheng; Wen-Lin Li; Chao-Yu Miao (Translational Stroke Research, 2020)
Stroke is the second leading cause of death and main cause of disability worldwide, but with few effective therapies. Although stem cell-based therapy has been proposed as an exciting regenerative medicine strategy for brain injury, there are limitations. The developed cerebral organoids (COs) represent a promising transplantation source for stroke that remains to be answered. Here, we transplanted COs at 55 days and explored the feasibility in the rat middle cerebral artery occlusion (MCAO) model of stroke. COs transplantation at 6 h or even 24 h after MCAO significantly reduces brain infarct volume and improves neurological motor function. Transplanted COs show the potential of multilineage differentiation to mimic in vivo cortical development, support motor cortex region-specific reconstruction, form neurotransmitter-related neurons, and achieve synaptic connection with host brain via in situ differentiation and cell replacement in stroke. Cells from transplanted COs show extensive migration into different brain regions along corpus callosum. The mechanisms underlying COs transplantation therapy are also associated with enhanced neurogenesis, synaptic reconstruction, axonal regeneration and angiogenesis, and decreased neural apoptosis with more survival neurons after stroke. Moreover, COs transplantation promotes predominantly exogenous neurogenesis in the transplantation periphery of ipsilateral cortex and predominantly endogenous neurogenesis in the hippocampus and subventricular zone. Together, we demonstrate the efficacy and underlying mechanisms of COs transplantation in stroke. This preliminary but promising study provides first-hand preclinical evidence for COs transplantation as a potential and effective intervention for stroke treatment.

Infusion of Human Mesenchymal Stem Cells Improves Regenerative Niche in Thioacetamide-Injured Mouse Liver - Ying-Hsien Kao; Yu-Chun Lin; Po-Huang Lee; Chia-Wei Lin; Po-Han Chen; Tzong-Shyuan Tai; Yo-Chen Chang; Ming-Huei Chou; Chih-Yang Chang; Cheuk-Kwan Sun (Tissue Engineering and Regenerative Medicine, 2020)

LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer’s disease - Chia-Hao Fan; Chia-Wei Lin; Hei-Jen Huang; Guey-Jen Lee-Chen; Ying-Chieh Sun; Wenwei Lin; Chiung-Mei Chen; Kuo-Hsuan Chang; Ming-Tsan Su; Hsiu Mei Hsieh-Li (Psychopharmacology, 2020)

Cloning and Characterization of a Ginsenoside-Hydrolyzing α-L-Arabinofuranosidase, CaAraf51, From Cellulosimicrobium aquatile Lyp51 - Sha-Sha Zuo; Yu-Chen Wang; Ling Zhu; Jiang-Yuan Zhao; Ming-Gang Li; Xiu-Lin Han; Meng-Liang Wen (Current Microbiology, 2020)

El Niño phase-dependent high-frequency variability in Western Equatorial Pacific - Ming Sun; Tim Li; Lin Chen (Climate Dynamics, 2020)

Strain-softening composite damage model of rock under thermal environment - Wen-lin Feng; Chun-sheng Qiao; Tan Wang; Ming-yuan Yu; Shuang-jian Niu; Zi-qi Jia (Bulletin of Engineering Geology and the Environment, 2020)

Sodium Para-aminosalicylic Acid Reverses Changes of Glutamate Turnover in Manganese-Exposed Rats - Zhao-Cong Li; Fang Wang; Shao-Jun Li; Lin Zhao; Jun-Yan Li; Yue Deng; Xiao-Juan Zhu; Yu-Wen Zhang; Dong-Jie Peng; Yue-Ming Jiang (Biological Trace Element Research, 2020)

Small RNA profiling reveal regulation of microRNAs in field peanut pod rot pathogen infection - Mian Wang; Chao-xin Zhang; Li-juan Pan; Tong Wang; Na Chen; Ming-na Chen; Zhen Yang; Xin-gang Guo; Shan-lin Yu; Xiao-yuan Chi (Biologia, 2020)

Antitumor activity on human bladder cancer T-24 cells and composition analysis of the core of Camellia osmantha fruit - Xi-Lin Ouyang; Li Yang; Lei Huang; Ying-Ming Pan (Natural Product Research, 2020)

Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study - Ming-Cheng Wang; Ahmad Imran Zaydi; Wei-Hung Lin; Jin-Seng Lin; Min-Tze Liong; Jiunn-Jong Wu (Probiotics and Antimicrobial Proteins, 2020)

Experimentally Induced Sepsis Causes Extensive Hypomyelination in the Prefrontal Cortex and Hippocampus in Neonatal Rats - Peixian Huang; Xuan Chen; Xiaoli Hu; Qiuping Zhou; Lanfen Lin; Shuqi Jiang; Hui Fu; Yajie Xiong; Hongke Zeng; Ming Fang; Chunbo Chen; Yiyu Deng (NeuroMolecular Medicine, 2020)

RGFP966 inactivation of the YAP pathway attenuates cardiac dysfunction induced by prolonged hypothermic preservation - Xiao-he Zheng; Lin-lin Wang; Ming-zhi Zheng; Jin-jie Zhong; Ying-ying Chen; Yue-liang Shen (Journal of Zhejiang University-SCIENCE B, 2020)

Future trends and guidance for the triple bottom line and sustainability: a data driven bibliometric analysis - Ming-Lang Tseng; Chia-Hao Chang; Chun-Wei Remen Lin; Kuo-Jui Wu; Qing Chen; Li Xia; Bing Xue (Environmental Science and Pollution Research, 2020)
This study conducts a comprehensive literature review of articles on the triple bottom line (TBL) published from January 1997 to September 2018 to provide significant insights and support to guide further discussion. There were three booms in TBL publications, occurring in 2003, 2011, and 2015, and many articles attempt to address the issue of sustainability by employing the TBL. This literature analysis includes 720, 132, and 58 articles from the Web of Science (WOS), Inspec, and Scopus databases, respectively, and reveals the gaps in existing research. To discover the barriers and points of overlap, these articles are categorized into six aspects of the TBL: economic, environmental, social, operations, technology, and engineering. Examining the top 3 journals in terms of published articles on each aspect reveals the research trends and gaps. The findings provide solid evidence confirming the argument that the TBL as currently defined is insufficient to cover the entire concept of sustainability. The social and engineering aspects still require more discussion to support the linkage of the TBL and to reinforce its theoretical basis. Additionally, to discover the gaps in the data sources, theories applied, methods adopted, and types of contributions, this article summarizes 82 highly cited articles covering each aspect. This article offers theoretical insights by identifying the top contributing countries, institutions, authors, keyword networks, and authorship networks to encourage scholars to push the current discussion further forward, and it provides practical insights to bridge the gap between theory and practice for enhancing the efficiency and effectiveness of improvements.

Potential probiotic of Lactobacillus strains isolated from the intestinal tracts of pigs and feces of dogs with antibacterial activity against multidrug-resistant pathogenic bacteria - Chuen-Fu Lin; Meng-Yi Lin; Chao-Nan Lin; Ming-Tang Chiou; Jia-Wen Chen; Kai-Chieh Yang; Ming-Cheng Wu (Archives of Microbiology, 2020)

Anthraquinone derivatives from a coral associated fungus Stemphylium lycopersici - Jiao Li; Yu-Bing Zheng; Tibor Kurtán; Ming-Xiang Liu; Hua Tang; Chun-Lin Zhuang; Wen Zhang (Natural Product Research, 2020)

Two new diprenylated flavanones from Derris laxiflora Benth - Hui-Chi Huang; Shih-Chang Chien; Ching-Chuan Kuo; Ming-Der Wu; Ming-Jen Cheng; Jih-Jung Chen; Hsi-Lin Chiu; Yueh-Hsiung Kuo (Natural Product Research, 2020)

Nitrogen and phosphorus co-starvation inhibits anthocyanin synthesis in the callus of grape berry skin - Hui-Zhen Zheng; Huan Wei; Shui-Huan Guo; Xin Yang; Ming-Xin Feng; Xu-Qiao Jin; Yu-Lin Fang; Zhen-Wen Zhang; Teng-Fei Xu; Jiang-Fei Meng (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Nakamurella albus sp. nov.: A Novel Actinobacterium Isolated from a Lichen Sample - Long-Qian Jiang; De-Feng An; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Lei Lang; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2020)

Experimental investigation for dynamic instability of coal-rock masses in horizontal section mining of steeply inclined coal seams - Zheng-yi Wang; Lin-ming Dou; Jiang He; An-ye Cao; Xiong-wei Li; Peng-bo Li; Chang-sheng Wu (Arabian Journal of Geosciences, 2020)

Ecological risk assessment of species impacted by fisheries in waters off eastern Taiwan - Chih‐Yu Lin; Sheng‐Ping Wang; Wei‐Chuan Chiang; Shane Griffiths; Hsin‐Ming Yeh (Fisheries Management and Ecology, 2020)
An ecological risk assessment was undertaken using productivity‐susceptibility analysis (PSA) to determine the relative vulnerability of 52 species caught by fisheries in the waters off eastern Taiwan. Overall, eight and 20 species were classified as having high and moderate vulnerability, respectively, and the remaining 24 species were classified as having low vulnerability. The species with the highest vulnerability scores were caught mainly by longline and gillnet fisheries, highlighting the need for improved data collection to facilitate a more detailed investigation using more quantitative methods. The data quality analysis indicated that the quality of data was classified as “moderate” for economically important species. However, many species were considered data‐limited and thus collecting high‐resolution catch and effort information and conducting biological studies, especially relating to age, growth and reproduction, are recommended to improve the reliability of outputs from data‐limited assessments such as PSA.

The Potential Pollution Risk of Groundwater by a Ceramic Permeable Brick Paving System - Zi-Zeng Lin; Hui-Ming Chen; Hai Yang (Water, Air, & Soil Pollution, 2020)

Release from below- and aboveground natural enemies contributes to invasion success of a temperate invader - Yuan-Zheng Zhao; Ming-Chao Liu; Yu-Long Feng; Dong Wang; Wei-Wei Feng; Keith Clay; Lekeah A. Durden; Xiu-Rong Lu; Shuo Wang; Xiao-Lin Wei; De-Liang Kong (Plant and Soil, 2020)

Selenium accumulation characteristics of Cyphomandra betacea (Solanum betaceum) seedlings - Linjin Lin; Jing Sun; Tonghao Cui; Xiong Zhou; Ming’an Liao; Yunmin Huan; Liu Yang; Caifang Wu; Xianmin Xia; Yuxi Wang; Zhiyu Li; Jinpeng Zhu; et al. (Physiology and Molecular Biology of Plants, 2020)

Astrocytic GABAB Receptors in Mouse Hippocampus Control Responses to Behavioral Challenges through Astrocytic BDNF - Ji-Hong Liu; Ze-Lin Li; Yi-Si Liu; Huai-De Chu; Neng-Yuan Hu; Ding-Yu Wu; Lang Huang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2020)

Doping TiO2 with CuSO4 enhances visible light photocatalytic activity for organic pollutant degradation - Mark Daniel G. de Luna; Sergi Garcia-Segura; Chinee H. Mercado; Yao-Tung Lin; Ming-Chun Lu (Environmental Science and Pollution Research, 2020)

Toxicity assessment of electrochemical advanced oxidation process-treated groundwater from a gas station with petrochemical contamination - How-Ran Chao; Danielle E. Que; Alisha C. Aquino; Yan-You Gou; Lemmuel L. Tayo; Yi-Hsien Lin; Ming-Hsien Tsai; Fu-Lin Hsu; I-Cheng Lu; Sheng-Lun Lin; Natwat Srikhao; Cherng-Gueih Shy; et al. (Environmental Monitoring and Assessment, 2020)

A novel putative betapartitivirus isolated from the plant-pathogenic fungus Rhizoctonia solani - Yi Chen; Jia En Su; Xi Yun Qin; Zhi Yong Fan; Xiao Hai Zhang; Qing Yu; Zhen Yuan Xia; Cong Ming Zou; Gao Kun Zhao; Zhong Long Lin (Archives of Virology, 2020)

Description of Gemmobacter aestuarii sp. nov., isolated from estuarine surface water and reclassification of Cereibacter changlensis as Gemmobacter changlensis Chen et al. 2013 - Asif Hameed; Mariyam Shahina; Shih-Yao Lin; Wen-Ming Chen; Yi-Han Hsu; Wei-An Lai; Chiu-Chung Young (Archives of Microbiology, 2020)

Comparative transcriptomic analysis of fireflies (Coleoptera: Lampyridae) to explore the molecular adaptations to fresh water - Qi‐Lin Zhang; Hong‐Wei Li; Zhi‐Xiang Dong; Xiao‐Jie Yang; Lian‐Bing Lin; Jun‐Yuan Chen; Ming‐Long Yuan (Molecular Ecology, 2020)
Aquatic insects are well adapted to freshwater environments, but the molecular basis of these adaptations remains largely unknown. Most firefly species (Coleoptera: Lampyridae) are terrestrial, but the larvae of several species are aquatic. Here, larval and adult transcriptomes from Aquatica leii (freshwater) and Lychnuris praetexta (terrestrial) were generated to test whether the genes associated with metabolic efficiency and morphology have undergone adaptive evolution to fresh water. The aquatic fireflies had a significantly lower ratio of nonsynonymous to synonymous substitutions than the terrestrial insects, indicating a genomewide evolutionary constraint in the aquatic fireflies. We identified 341 fast‐evolving genes and 116 positively selected genes in the aquatic fireflies. Of these, 76 genes exhibiting both fast evolution and positive selection were primarily involved in ATP production, energy metabolism and the hypoxia response. We identified 7,271 differentially expressed genes (DEGs) in A . leii (adults versus larvae) and 8,309 DEGs in L . praetexta (adults versus larvae). DEGs specific to the aquatic firefly ( n = 1,445) were screened via interspecific comparisons ( A . leii versus L . praetexta ) and were significantly enriched for genes involved in metabolic efficiency (e.g., ATP production, hypoxia, and immune responses) and certain aspects of morphology (e.g., cuticle chitin, tracheal and compound eye morphology). These results indicate that sequence and expression‐level changes in genes associated with both metabolic efficiency and morphological attributes related to the freshwater lifestyle contributed to freshwater adaptation in fireflies. This study provides new insights into the molecular mechanisms of aquatic adaptation in insects.

Population Genetic Analysis for Stock Enhancement of Silver Sea Bream (Rhabdosargus sarba) in Taiwan - Te-Hua Hsu; Chang-Wen Huang; Hung-Tai Lee; Yi-Hsuan Kuo; Kwang-Ming Liu; Cheng-Hui Lin; Hong-Yi Gong (Fishes, 2020)
Stock enhancement is a method for replenishing depleted wild finfish populations by supplementing them with hatchery-raised fish. In Taiwan, silver sea bream (Rhabdosargus sarba) is a predominant commercial species involved in stock enhancement projects. Although management agencies conduct stock enhancement projects, there are a lot of private releases without records. Stock enhancement is performed by the private aquaculture sector without accurate genetic records, potentially leading to unintended consequences for wild populations. We analyzed the genetics of 459 wild and 701 hatchery-reared specimens from nine batches produced by various hatcheries. Wild and hatchery-reared samples could be considered two separate clades by using a set of stable and informative microsatellite markers including type I (from gene introns and 3′UTR) and type II markers (randomly picked up from genome). Type I microsatellite markers could more sensitively reflect the loss of genetic diversity more than type II markers in the domestication process. All specimens were considered native by using mtDNA COI and microsatellites. The genetic composition of the wild population is relatively simple, and the estimated low contribution rate of the hatchery stock (1.3–10.9%; 6–50/459) indicated a weak but significant genetic effect of stock enhancement. Therefore, establishing standards for the stock enhancement of silver sea bream for more effective supplementation of wild populations is imperative.

Strength attenuation effects on rate-dependent law of stress development of frozen sand - Xiao-Liang Yao; Ji-Lin Qi; Ming-Yi Zhang; Fan Yu (European Journal of Environmental and Civil Engineering, 2020)

Outflow sediment concentration forecasting by integrating machine learning approaches and time series analysis in reservoir desilting operation - Ming-Jui Chang; Gwo-Fong Lin; Fong-Zuo Lee; Yi-Cheng Wang; Peng-An Chen; Ming-Chang Wu; Jihn-Sung Lai (Stochastic Environmental Research and Risk Assessment, 2020)

Correlations Between Skin Barrier Integrity and Delivery of Hydrophilic Molecules in the Presence of Penetration Enhancers - XueKe Lin; ZhenHua Wang; HuiLong Ou; Samir Mitragotri; Ming Chen (Pharmaceutical Research, 2020)

Large paleo-rockslide induced by buckling failure at Jiasian in Southern Taiwan - Che-Ming Yang; Keng-Hao Kang; Shun-Hsing Yang; Kuo-Wei Li; Hui-Jung Wang; Yin-Tsan Lee; Kuei-Kun Lin; Yii-Wen Pan; Jyh-Jong Liao (Landslides, 2020)

Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China - Cheng-yi Lin; Die Li; Jie-ming Lu; Zhe-bin Yu; Yao Zhu; Peng Shen; Meng-ling Tang; Ming-juan Jin; Hong-bo Lin; Li-ming Shui; Kun Chen; Jian-bing Wang (Environmental Science and Pollution Research, 2020)

The maize B chromosome is capable of expressing microRNAs and altering the expression of microRNAs derived from A chromosomes - Yen-Hua Huang; Shu-Fen Peng; Yao-Pin Lin; Ya-Ming Cheng (Chromosome Research, 2020)

Combined effect of polymorphisms of MTHFR and MTR and arsenic methylation capacity on developmental delay in preschool children in Taiwan - Yu-Mei Hsueh; Ying-Chin Lin; Chi-Jung Chung; Ya-Li Huang; Ru-Lan Hsieh; Pai-Tsang Huang; Mei-Yi Wu; Horng-Sheng Shiue; Ssu-Ning Chien; Chih-Ying Lee; Ming-I. Lin; Shu-Chi Mu; et al. (Archives of Toxicology, 2020)

Hypertrophic olivary degeneration: a single case report - Wei Jiang; Xiao-Zhong Jing; Lin Gan; Ming Dong; Peng Yu (Acta Neurologica Belgica, 2020)

Two new xanthone glycosides from Swertia punicea Hemsl. and their anti-inflammatory activity - Lin-Yun Mou; Hai-Yan Wu; En-Guang Ma; Ming-Feng Wang; Yan-Qing Duan; Sheng Lei; Gan-Peng Li (Natural Product Research, 2020)

Clinical strategies for differentiating IgG4-related cholecystitis from gallbladder carcinoma to avoid unnecessary surgical resection - Rui Zhang; Hao-Ming Lin; Zhao-Xi Cai; Su-Juan Du; Hong Zeng; Lei-Bo Xu; Jie Wang; Chao Liu (Science China Life Sciences, 2020)