Altered Connectedness of the Brain Chronnectome During the Progression to Alzheimer’s Disease - Maryam Ghanbari; Zhen Zhou; Li-Ming Hsu; Ying Han; Yu Sun; Pew-Thian Yap; Han Zhang; Dinggang Shen (Neuroinformatics, 2022)

Water adsorption characteristic and its impact on pore structure and methane adsorption of various rank coals - Ming-yi Chen; Xiao-yun Chen; Liang Wang; Fu-chao Tian; Yu-meng Yang; Xue-jie Zhang; Ya-pu Yang (Environmental Science and Pollution Research, 2022)

An efficient micropropagation protocol, chemical components, and hypoglycemic activity for Cremastra appendiculata (D. Don) Makino pseudobulbs - Ningxian Yang; Daoping Wang; Yanyan Gao; Enming Hu; Xiaosong Yu; Sijing Peng; Jun Ji; Ming-sheng Zhang (In Vitro Cellular & Developmental Biology - Plant, 2022)

Effects of different stocking densities on the growth performance and antioxidant capacity of Chinese mitten crab (Eriocheir sinensis) in rice crab culture system - Xin Wang; Qi Yao; Xin-yu Lei; Dong-ming Zhang; Sen Wang; Ji-wu Wan; Hong-jian Liu; Yu-ke Chen; Yun-long Zhao; Gui-qin Wang; Qiu-ju Wang; Zhi-xin Guo (Aquaculture International, 2022)

An Isentropic Mass Circulation View on the Extreme Cold Events in the 2020/21 Winter - Yueyue Yu; Yafei Li; Rongcai Ren; Ming Cai; Zhaoyong Guan; Wei Huang (Advances in Atmospheric Sciences, 2022)

Isolated intracranial xanthogranuloma involving the Meckel’s cave in an adult: a case report - Yang Wen; Yu-mei Li; Biao Zhu; Xin Liu; Ming Zhao (Acta Neurologica Belgica, 2022)

Anti-inflammatory constituents from Phyllostachys makinoi Hayata - Chia-Ching Liaw; Yu-Chi Lin; Shao-Yu Wu; Jenny Chun-Ling Kuo; Zhi-Hu Lin; Kai-Wei Lin; Huang Hui-Chi; Li-Ming Yang Kuo; Yao-Haur Kuo (Natural Product Research, 2022)

Age and Growth of the Spot-Tail Shark, Carcharhinus sorrah, in the Taiwan Strait - Shoou-Jeng Joung; Zhi-Yu Hsu; Kuan-Yu Su; Kwang-Ming Liu (Journal of Marine Science and Engineering, 2022)
The age and growth of the spot-tail shark, Carcharhinus sorrah, were estimated based on 327 specimens (171 females and 156 males) captured by the coastal/offshore longline or drift net fishery in the waters of the Taiwan Strait from October 2010 to December 2011 and July 2019 to August 2021. Sex-specific whole weight (W)—curved total length (TL) relationships were estimated as follows: W = 7.0 × 10−6 TL2.9313 (n = 171, and p

Avilamycin production enhancement by mutagenesis and fermentation optimization in Streptomyces viridochromogenes - Guanghai Yu; Haifen Peng; Jian Cao; Aimei Liao; Pan Long; Jihong Huang; Ming Hui (World Journal of Microbiology and Biotechnology, 2022)

MeSPL9 attenuates drought resistance by regulating JA signaling and protectant metabolite contents in cassava - Shuxia Li; Zhihao Cheng; Zhibo Li; Shiman Dong; Xiaoling Yu; Pingjuan Zhao; Wenbin Liao; Xiang Yu; Ming Peng (Theoretical and Applied Genetics, 2022)

Inherent conflicts between reaction norm slope and plasticity indices when comparing plasticity: a conceptual framework and empirical test - Shuo Wang; Wei-Wei Feng; Ming-Chao Liu; Kai Huang; Pieter A. Arnold; Adrienne B. Nicotra; Yu-Long Feng (Oecologia, 2022)

Vermicompost Application Enhances Halophyte Suaeda salsa Performance and Improves Coastal Saline Soil Quality - Jing-Fang Cai; Xuan-Shao Liu; Kai Sun; Fan Jiang; Ming-Xiang Zhang; Hong-Li Li; Fei-Hai Yu (Journal of Soil Science and Plant Nutrition, 2022)

3D Seismic Stability Analysis of Bench Slope with Pile Reinforcement - Sheng-yu Yang; Zhen Wang; Jia-man Wang; Ming-wei Gong; Jian-fei Li; Zhi-bin Sun (Geotechnical and Geological Engineering, 2022)

Identification of structural variation and polymorphisms of a sex co-segregating scaffold in spinach - Li’ang Yu; Xiaokai Ma; William Wadlington; Ray Ming (Plant Reproduction, 2022)

Three-dimensional forward modeling and response characteristics analysis of foundation pit leakage electric-field considering electrokinetic effect - Chen Yu-Feng; Chen Hui; Deng Ju-Zhi; Liu Sui-Ming; Tang Wen-Wu; Wang Shuo (Applied Geophysics, 2022)

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae - Ying‐Ying Cai; Jing‐Yi Wang; Xi‐Yu Wu; Shuang Liang; Xue‐Ming Zhu; Lin Li; Jian‐Ping Lu; Xiao‐Hong Liu; Fu‐Cheng Lin (Environmental Microbiology, 2022)
Summary The development and pathogenicity of the fungus Magnaporthe oryzae , the causal agent of destructive rice blast disease, require it to perceive external environmental signals. Opy2, an overproduction‐induced pheromone‐resistant protein 2, is a crucial protein for sensing external signals in Saccharomyces cerevisiae . However, the biological functions of the homologue of Opy2 in M. oryzae are unclear. In this study, we identified that MoOPY2 is involved in fungal development, pathogenicity, and autophagy in M. oryzae . Deletion of MoOPY2 resulted in pleiotropic defects in hyphal growth, conidiation, germ tube extension, appressorium formation, appressorium turgor generation, and invasive growth, therefore leading to attenuated pathogenicity. Furthermore, MoOpy2 participates in the Osm1 MAPK pathway and the Mps1 MAPK pathway by interacting with the adaptor protein Mst50. The interaction sites of Mst50 and MoOpy2 colocalized with the autophagic marker protein MoAtg8 in the preautophagosomal structure sites (PAS). Notably, the Δ Moopy2 mutant caused cumulative MoAtg8 lipidation and rapid GFP‐MoAtg8 degradation in response to nitrogen starvation, showing that MoOpy2 is involved in the negative regulation of autophagy activity. Taken together, our study revealed that MoOpy2 of M. oryzae plays an essential role in the orchestration of fungal development, appressorium penetration, autophagy and pathogenesis.

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Prevalence, complete genome, and metabolic potentials of a phylogenetically novel cyanobacterial symbiont in the coral‐killing sponge, Terpios hoshinota - Yu‐Hsiang Chen; Hsing‐Ju Chen; Cheng‐Yu Yang; Jia‐Ho Shiu; Daphne Z. Hoh; Pei‐Wen Chiang; Wenhua Savanna Chow; Chaolun Allen Chen; Tin‐Han Shih; Szu‐Hsien Lin; Chi‐Ming Yang; James Davis Reimer; et al. (Environmental Microbiology, 2022)
Summary Terpios hoshinota is an aggressive, space‐competing sponge that kills various stony corals. Outbreaks of this species have led to intense damage to coral reefs in many locations. Here, the first large‐scale 16S rRNA gene survey across three oceans revealed that bacteria related to the taxa Prochloron , Endozoicomonas , SAR116, Ruegeria , and unclassified Proteobacteria were prevalent in T . hoshinota . A Prochloron ‐related bacterium was the most dominant and prevalent cyanobacterium in T . hoshinota . The complete genome of this uncultivated cyanobacterium and pigment analysis demonstrated that it has phycobiliproteins and lacks chlorophyll b , which is inconsistent with the definition of Prochloron . Furthermore, the cyanobacterium was phylogenetically distinct from Prochloron , strongly suggesting that it should be a sister taxon to Prochloron . Therefore, we proposed this symbiotic cyanobacterium as a novel species under the new genus Candidatus Paraprochloron terpiosi. Comparative genomic analyses revealed that ‘Paraprochloron’ and Prochloron exhibit distinct genomic features and DNA replication machinery. We also characterized the metabolic potentials of ‘Paraprochloron terpiosi’ in carbon and nitrogen cycling and propose a model for interactions between it and T. hoshinota . This study builds a foundation for the study of the T . hoshinota microbiome and paves the way for better understanding of ecosystems involving this coral‐killing sponge.

Genetic Diversity and Structure of Tropical Porites lutea Populations Highlight Their High Adaptive Potential to Environmental Changes in the South China Sea - Yanqiu Luo; Wen Huang; Kefu Yu; Ming Li; Biao Chen; Xueyong Huang; Zhenjun Qin (Frontiers in Marine Science, 2022)
Global climate change and anthropogenic disturbance have significantly degraded biodiversity in coral reef ecosystems. The genetic potential and adaptability of corals are key factors used to predict the fate of global coral reefs under climate change. In this study, we used eight microsatellite loci to study the patterns of reproduction, genetic diversity, and genetic structure of 302 Porites lutea samples across 13° latitudes in the South China Sea (8.8644°N–22.6117°N). The results indicated that P. lutea reproduces largely via sexual reproduction on scales of 5 m and greater and has abundant gene diversity. Additionally, the tropical populations harbored high genetic diversity (based on alleles, effective number of alleles, gene diversity, and heterozygosity). In contrast, genetic diversity was lower in subtropical coral populations. Genetic variation values and pairwise F ST revealed that tropical and subtropical populations had significantly different genetic structures. Finally, the Mantel tests showed that the genetic differentiation and genetic variation of P. lutea were strongly correlated with sea surface temperature and slightly correlated with geographical distance. These results indicated that tropical P. lutea populations have high genetic potential and adaptability because of their sexual reproduction and genetic diversity, giving them a greater capacity to cope with climate change. Subtropical coral populations showed lower genetic diversity and, thus, relatively poor genetic resilience in response to low average sea surface temperature and human activities. Our study provides a theoretical basis for the protection and restoration of coral reefs.

A Novel Method of Trajectory Optimization for Underwater Gliders Based on Dynamic Identification - Ming Yang; Yanhui Wang; Yan Liang; Yu Song; Shaoqiong Yang (Journal of Marine Science and Engineering, 2022)
For underwater gliders (UGs), high trajectory accuracy is an important factor in improving the observation of ocean phenomena. In this paper, a novel method of trajectory optimization is proposed to increase the trajectory accuracy of UGs, which is approximately based on the nonlinear dynamic model, rather than the linearization model. Firstly, a dynamic model of UGs is established to analyze the effect of the input parameters on the trajectory error, based on some approximate models that replaced the dynamic model due to its strong nonlinearity. Then, an identification strategy for the trajectory error is proposed, and the trajectory optimization strategy is analyzed while considering gliding range loss and observation distance loss. Finally, the identification strategy and trajectory optimization strategy proposed in this paper are verified by a sea trial of Petrel-L. The dynamic model, identification strategy, and optimization strategy are appropriate for other UGs.

Phylogeography and Genetic Structure of the Swimming Crabs Portunus sanguinolentus (Herbst, 1783) in East Asia - Yu-Ming Lu; Chun-Han Shih; Po-Cheng Chen; Wei-Chieh Kao; Ying-Chou Lee; Yu-San Han; Tzong-Der Tzeng (Journal of Marine Science and Engineering, 2022)
The three-spot swimming crab (Portunus sanguinolentus) is mainly distributed in South East Asia. An analysis of mitochondrial control region partial sequences allows us to determine the population genetic structure, phylogeography and historical demography of this species in East Asia. The seven populations, which included 110 individuals, were collected from mainland China (Shanghai, SH, Xiamen, XM and Hong Kong, HK), Taiwan (Yilan, YL, Taichung, TC, Donggang, DG) and Singapore (Singapore, SGP). The nucleotide diversity (π) of all individuals was 0.01149, with values ranging from 0.00372 (SGP) to 0.01345 (YL). In total, 90 haplotypes have been identified, which can be divided into two major lineages: lineage A consists of specimens from SH, YL, XM, TC and DG, and lineage B corresponds to specimen from SGP. From the second to the most recent interglacial period, population expansion was observed in each lineage. However, a low level of genetic differentiation was also observed in the three-spotted swimming crab, P. sanguinolentus, according to FST values. Our results suggest that several past and present habitat configurations have shaped the genetic patterns of P. sanguinolentus until now. During Pleistocene glaciations, when sea levels were low, this species may have moved along the coast from Southeast Asia to China. It first colonized the Hong Kong area during this era. After sea levels rose and shorelines receded, it subsequently spread to the coast of mainland China.

Utilization of synchrotron-based and globar-sourced mid-infrared spectroscopy for faba nutritional research about molecular structural and nutritional interaction - Ming Yan; Víctor H. Guevara-Oquendo; María E. Rodríguez-Espinosa; Jen-Chieh Yang; Herbert (Bart) Lardner; David A. Christensen; Xin Feng; Peiqiang Yu (Critical Reviews in Food Science and Nutrition, 2022)

Population Genomics, Transcriptional Response to Heat Shock, and Gut Microbiota of the Hong Kong Oyster Magallana hongkongensis - Yichun Xie; Elaine Y. Y. Huang; Wenyan Nong; Sean T. S. Law; Yifei Yu; Khan Cheung; Yiqian Li; Cheuk Fung Wong; Ho Yin Yip; Patrick W. S. Joyce; King Ming Chan; Ka Hou Chu; et al. (Journal of Marine Science and Engineering, 2022)
The Hong Kong oyster Magallana hongkongensis, previously known as Crassostrea hongkongensis, is a true oyster species native to the estuarine-coast of the Pearl River Delta in southern China. The species—with scientific, ecological, cultural, and nutritional importance—has been farmed for hundreds of years. However, there is only limited information on its genetics, stress adaptation mechanisms, and gut microbiota, restricting the sustainable production and use of oyster resources. Here, we present population structure analysis on M. hongkongensis oysters collected from Deep Bay and Lantau Island in Hong Kong, as well as transcriptome analysis on heat shock responses and the gut microbiota profile of M. hongkongensis oysters collected from Deep Bay. Single nucleotide polymorphisms (SNPs), including those on the homeobox genes and heat shock protein genes, were revealed by the whole genome resequencing. Transcriptomes of oysters incubated at 25 °C and 32 °C for 24 h were sequenced which revealed the heat-induced regulation of heat shock protein pathway genes. Furthermore, the gut microbe community was detected by 16S rRNA sequencing which identified Cyanobacteria, Proteobacteria and Spirochaetes as the most abundant phyla. This study reveals the molecular basis for the adaptation of the oyster M. hongkongensis to environmental conditions.

Tectonic Evolution of the Meso-Tethys Ocean: Insights from Geochemistry and Geochronology of the Jurassic ophiolitic complex in the Asa area, central Tibet - Xiaowen Zeng; Ming Wang; Yunpeng Yu; Hang Li; Xianjin Zeng; Di Shen (International Geology Review, 2022)

Top-Down aircraft detection in large-scale scenes based on multi-source data and FEF-R-CNN - Beichen Zeng; Dongping Ming; Fengcheng Ji; Jiawei Yu; Lu Xu; Liang Zhang; Xinyi Lian (International Journal of Remote Sensing, 2022)

Comparative transcriptome analysis revealed the molecular mechanism of the effect of light intensity on the accumulation of rhynchophylline and isorhynchophylline in Uncaria rhynchophylla - Xiao-Hong Wang; Xue Li; Wei Qiang; Xiao-Song Yu; Hao-Jie Zheng; Ming-Sheng Zhang (Physiology and Molecular Biology of Plants, 2022)

Oxygen Metabolism-induced Stress Response Underlies Heart–brain Interaction Governing Human Consciousness-breaking and Attention - Xiao-Juan Xue; Rui Su; Ze-Feng Li; Xiao-Ou Bu; Peng Dang; Si-Fang Yu; Zhi-Xin Wang; Dong-Mei Chen; Tong-Ao Zeng; Ming Liu; Hai-Lin Ma; De-Long Zhang (Neuroscience Bulletin, 2022)

Screening and stability analysis of reference genes in fasting caecotrophy model in rabbits - Hui He; Zhichao Li; Mengke Ni; Shanshan Xing; Lei Yu; Huifen Xu; Dehu Zhuo; Ming Li (Molecular Biology Reports, 2022)

The anaerobic oxidation of methane driven by multiple electron acceptors suppresses the release of methane from the sediments of a reservoir - Xueping Chen; Meilin Yang; Jing Sun; Juan Yu; Lihua Liu; Shuang Bai; Fayan Bai; Ming Yang; Zheng Chen; Chiquan He; Xiaoyan Liu; Jing Liang; et al. (Journal of Soils and Sediments, 2022)

Exogenous IAA Alleviates Arsenic Toxicity to Rice and Reduces Arsenic Accumulation in Rice Grains - Yue He; Ting Zhang; Yu Sun; Xuejing Wang; Qingqing Cao; Zhigang Fang; Ming Chang; Qingsheng Cai; Laiqing Lou (Journal of Plant Growth Regulation, 2022)

Overexpression of IbMPK3 increases low-temperature tolerance in transgenic sweetpotato - Rong Jin; Ho Soo Kim; Tao Yu; Ming Liu; Wenhui Yu; Peng Zhao; Aijun Zhang; Qiangqiang Zhang; Yaju Liu; Qinghe Cao; Sang-Soo Kwak; Zhonghou Tang (Plant Biotechnology Reports, 2022)

Effect of freeze—thaw cycle on hydraulic conductivity of compacted clayey soil - Lei Guo; Qi-hao Yu; Na Yin; Dong-ming Zhang; Deng-ping Zhang; Xiu-ling Ren; Yan-hui You; Zhen-yu Zhang; Hui Bing; Shi-jie Chen (Journal of Mountain Science, 2022)

Evidence for niche conservatism in alpine beetles under a climate‐driven species pump model - Jillian Schat; Yi‐Ming Weng; Roman Yu. Dudko; David H. Kavanaugh; Lan Luo; Sean D. Schoville (Journal of Biogeography, 2022)
Aim Past glacial cycles have generated lineage diversity in alpine habitats, acting as a climate‐driven species pump. It is not clear how much this process contributes to ecological diversification of alpine species. To examine this problem, we test patterns of genetic and phenotypic divergence in two co‐distributed species complexes of flightless alpine ground beetles. Greater differentiation in functional traits would indicate that ecological selection is an outcome of oscillating climate change, whereas greater differentiation in non‐ecological traits would indicate niche conservatism. Location The Cascades Range and Trinity Mountains of western North America. Taxon Nebria paradisi and N . vandykei species complexes (Insecta: Coleoptera: Carabidae: Nebriinae). Methods We generated genome‐wide single nucleotide polymorphism data and mitochondrial sequence data, as well as morphological and physiological data, to compare populations spanning the range of both species. Phylogenetic and population genetic analyses were used to infer relationships among taxa and populations in each species complex, as well as historical demography. Support vector machines were used to test for classification of taxa and populations based on ecomorphological, ecophysiological and male reproductive traits. Mantel tests were then used to assess associations between phenotypic and genetic divergence among populations. Results The N . vandykei and N . paradisi species complexes are each comprised of genetically distinctive populations exhibiting long‐term demographic declines. Each phylogeny supports multiple monophyletic groups with geographical cohesion. By examining phenotypic traits among populations in both species’ complexes, we show that reproductive trait divergence can discriminate species and population status more effectively than ecomorphological or ecophysiological traits. Reproductive and genetic divergence are significantly correlated in the N . vandykei species complex. Main Conclusions We found limited evidence of ecological selection acting on functional traits. Instead, reproductive and genetic divergence evolved among isolated populations in both species complexes, suggesting niche conservatism may be a common outcome in alpine species diversification.

Structure reassignment of two triterpenes with CASE algorithms and DFT chemical shift predictions - Zhi-Kang Duan; Tian-Ming Lv; Guan-Shan Song; Yu-Xi Wang; Bin Lin; Xiao-Xiao Huang (Natural Product Research, 2022)

Nanofiltration Membrane Fouling and Control Caused by Residual Aluminum in Feed Water - Hui-Bo Yu; Xian-Qiu Zhang; Xue Han; Zhen-Zhen Yang; Ya-Wen Zhou; Wen Ding; Ming-Xia Du (Water, Air, & Soil Pollution, 2022)

A Macro-microscopic Coupled Constitutive Model for Fluid-Saturated Porous Media with Compressible Constituents - Jia-Yu Liang; Yue-Ming Li; Erich Bauer (Transport in Porous Media, 2022)

Glutamatergic Neurons in the Caudal Zona Incerta Regulate Parkinsonian Motor Symptoms in Mice - Li-Xuan Li; Yu-Lan Li; Jin-Tao Wu; Ji-Zhou Song; Xiao-Ming Li (Neuroscience Bulletin, 2022)

Joint-Tissue Integrative Analysis Identified Hundreds of Schizophrenia Risk Genes - Yong Wu; Xiao-Lin Yu; Xiao Xiao; Ming Li; Yi Li (Molecular Neurobiology, 2022)

A contribution to knowledge of Gyroporus (Gyroporaceae, Boletales) in China: three new taxa, two previous species, and one ambiguous taxon - Hui-Jing Xie; Li-Ping Tang; Man Mu; Yu-Guang Fan; Shuai Jiang; Ming-Sheng Su; Zhi-Qun Liang; Nian-Kai Zeng (Mycological Progress, 2022)

Scalp Acupuncture Protects Against Neuronal Ferroptosis by Activating The p62-Keap1-Nrf2 Pathway in Rat Models of Intracranial Haemorrhage - Ming-Yue Li; Xiao-Hong Dai; Xue-Ping Yu; Wei Zou; Wei Teng; Peng Liu; Xin-Yang Yu; Qi An; Xin Wen (Journal of Molecular Neuroscience, 2022)
Intracerebral haemorrhage (ICH) can be a catastrophic event; even if the initial stages of the pathology were well-managed, a number of patients experience varied residual neurological deficits following the insult. Ferroptosis is a recently identified type of cell demise which is tightly linked to the neurological impairment associated with ICH. In the current work, the prophylactic impact of scalp acupuncture (SA) therapy on autologous blood injection murine models of ICH was investigated in order to establish whether SA could mitigate the secondary damage arising following ICH by moderating ferroptosis. The pathophysiological mechanisms associated with this process were also explored. Ludmila Belayev tests were utilised for the characterisation of neurological damage. Haematoxylin–eosin staining was employed in order to determine the cerebral impact of the induced ICH. Malondialdehyde (MDA) and iron titres in peri-haemorrhagic cerebral tissues were appraised using purchased assay kits. Transmission electron microscopy delineated mitochondrial appearances within nerve cell bodies from the area of haemorrhage. Western blotting techniques were utilised to assay the degree of protein expression of NeuN, sequestosome 1 (p62), nuclear factor erythroid 2-related factor 2 (Nrf2), Kelch-like ECH-associated protein 1 (Keap1), glutathione peroxidase 4 (GPX4) and ferritin heavy chain 1 (FTH1). The frequencies of Nrf2, GPX4 and FTH1 positive cells, respectively, were documented with immunohistochemical staining. The results demonstrated that therapy with SA after ICH mitigated MDA and iron sequestration, diminished the appearance of contracted mitochondria with increased outer mitochondrial membrane diameter within the nerve cell bodies, and suppressed neuronal ferroptosis. The pathways responsible for these effects may encompass amplified p62, Nrf2, GPX4 and FTH1 expression, together with decreased Keap1 expression. Application of SA reduced identified neurobehavioural abnormalities after ICH; no disparities were observed between the consequences of SA therapy and deferoxamine delivery. It can be surmised that intervention with SA enhanced recovery after ICH by triggering the antioxidant pathway, p62/Keap1/Nrf2, and causing FTH1 and GPX4 upregulation, factors that participate in diminishing excess iron and thus in mitigating lipid peroxidation insults arising from ferroptosis following ICH.

YAP regulates porcine skin-derived stem cells self-renewal partly by repressing Wnt/β-catenin signaling pathway - Hong-Chen Yan; Yu Sun; Ming-Yu Zhang; Shu-Er Zhang; Jia-Dong Sun; Paul W. Dyce; Francesca Gioia Klinger; Massimo De Felici; Wei Shen; Shun-Feng Cheng (Histochemistry and Cell Biology, 2022)

Are electric vehicles cost competitive? A case study for China based on a lifecycle assessment - Lai Yang; Biying Yu; Gabriel Malima; Bo Yang; Hao Chen; Yi-Ming Wei (Environmental Science and Pollution Research, 2022)

Analytical model for uncertainty characterization of fracture intensity measurement in rock masses - Yu-Chen Lu; Yong-Ming Tien; Charng Hsein Juang; Himatul Farichah; Che-Jui Hsu; Van-Binh Bui (Bulletin of Engineering Geology and the Environment, 2022)

Astragalus Polysaccharide Protects Against Cadmium-Induced Autophagy Injury Through Reactive Oxygen Species (ROS) Pathway in Chicken Embryo Fibroblast - Xudong Shen; Zequn Tang; Yu Bai; Meishuo Wan; Miao Yu; Jingyi Chen; Guangxing Li; Ruili Zhang; Ming Ge (Biological Trace Element Research, 2022)

Quantitative estimation of hourly precipitation in the Tianshan Mountains based on area-to-point kriging downscaling and satellite-gauge data merging - Xin-yu Lu; Yuan-yuan Chen; Guo-qiang Tang; Xiu-qin Wang; Yan Liu; Ming Wei (Journal of Mountain Science, 2022)

Isolation and partial characterization of a novel bacteriocin from Pseudomonas azotoformans with antimicrobial activity against Pasterella multocida - Yu Wang; Shuang Lei; Inam Muhammad; Yu Jia; Cheng-guang He; Yi-Ming Wang; Yun-Hang Gao; Ling-Cong Kong; Hong-Xia Ma (Archives of Microbiology, 2022)

Viridibacillus soli sp. nov., isolated from forest soil in Ailaoshan National Nature Reserve - Yan Xu; Jiang-Yuan Zhao; Yu Geng; Hui-Ren Yuan; Le-Le Li; Meng-Liang Wen; Ming-Gang Li; Shu-Kun Tang (Archives of Microbiology, 2022)

Alteribacter salitolerans sp. nov., isolated from a saline-alkaline soil - Shuang Wang; Lei Sun; Manik Prabhu Narsing Rao; Guo-Hong Liu; Pin-Jiao Jin; Zhou-Yan Dong; Zheng-Han Lian; Xiao-Yu Hao; Ming-Yi Zhang; Wen-Jun Li (Archives of Microbiology, 2022)

Propioniciclava soli sp. nov., isolated from forest soil, Yunnan, China, and reclassification of the genus Brevilactibacter into the genus Propioniciclava, and Brevilactibacter sinopodophylli, Brevilactibacter flavus, and Brevilactibacter coleopterorum as Propioniciclava sinopodophylli comb. nov., Propioniciclava flava comb. nov., and Propioniciclava coleopterorum comb. nov., respectively - Le-Le Li; Jiang-Yuan Zhao; Yu Geng; Yu-Guang Zhou; Hui-Ren Yuan; Man Cai; Meng-Liang Wen; Ming-Gang Li; Shu-Kun Tang (Archives of Microbiology, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Sarcodia suieae Acetyl-Xylogalactan Regulates Nile Tilapia (Oreochromis niloticus) Tissue Phagocytotic Activity and Serum Indices - Po-Kai Pan; Tsung-Meng Wu; Chiu-Ming Wen; Yin-Yu Chen; Yu-Sheng Wu (Journal of Marine Science and Engineering, 2021)
Sarcodia suieae acetyl-xylogalactan was reported to induce macrophage polarisation, and could positively regulate macrophage activation. In this study, we evaluated the effect of Sarcodia suieae acetyl-xylogalactan on the Nile tilapia. First, we assessed the influence of acetyl-xylogalactan on the survival, glucose uptake, and phagocytic activity of tilapia head kidney (THK) melanomacrophage, and observed increased proliferation of these cells in the MTT assay after 12 and 24 h of treatment. Glucose uptake increased in THK melanomacrophage treated with 20 and 30 μg acetyl-xylogalactan for 24 h. Their phagocytic activity was positively enhanced following exposure to acetyl-xylogalactan. Nile tilapia were fed with acetyl-xylogalactan for 4 weeks. At the end of the experiment, Nile tilapia were sacrificed, and the lipopolysaccharide-induced liver and head-kidney apoptosis was examined under reducing conditions in comparison with controls. The phagocytic activities of liver and head-kidney cells were enhanced after 4 weeks of feeding. Blood biochemical analysis revealed a reduction in glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) levels after 4 weeks of feeding. Combined with in vitro and in vivo experiments results, the extracted S. suieae acetyl-xylogalactan could directly induce THK melanomacrophage proliferation, glucose uptake, and phagocytic activity. Acetyl-xylogalactan was able to induce Nile tilapia liver and head-kidney resident macrophage activity, and reduced LPS-induced liver and head-kidney cell apoptosis. S. suieae acetyl-xylogalactan may modulate Nile tilapia macrophage activation by polarising them into M1 macrophages to improve the Nile tilapia nonspecific immune response.

The role of carbonic anhydrase III and autophagy in type 2 diabetes with cardio-cerebrovascular disease - Xiao-Ming Zhang; Ying-Hong Tao; Xiu-Ling Zhou; Xi-Liang Shang; Xiao-Bo Gong; Ying-Chao Liu; Yan-Yan Huang; Gang Chen; Zhong-Yu Yu; Jian-Tao Wang; Zun-Guo Du; Guo-Feng Wu; et al. (Metabolic Brain Disease, 2021)
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases among the elderly people. The T2DM increases the risk of cardio-cerebrovascular disease (CCD), and the main pathological change of the CCD is atherosclerosis (AS). Meanwhile, the carbonic anhydrases (CAs) are involved in the formation and progression of plaques in AS. However, the exact physiological mechanism of carbonic anhydrase III (CAIII) has not been clear yet, and there are also no correlation study between CAIII protein and T2DM with CCD. The 8-week old diabetic mice (db/db −/− mice) and wild-type mice (wt mice) were feed by a normal diet till 32 weeks, and detected the carotid artery vascular opening angle using the method of biomechanics; The changes of cerebral cortex and myocardium were watched by the ultrastructure, and the autophagy were observed by electron microscope; The tissue structure, inflammation and cell injury were observed by Hematoxylin and eosin (HE) staining; The apoptosis of cells were observed by TUNEL staining; The protein levels of CAIII, IL-17, p53 were detected by immunohistochemical and Western Blot, and the Beclin-1, LC3, NF-κB were detected by Western Blot. All statistical analysis is performed using PRISM software. Compared with wt mice, db/db −/− mice’ carotid artery open angle increased significantly. Electron microscope results indicated that autophagy in db/db −/− mice cerebral cortex and heart tissue decreased and intracellular organelle ultrastructure were damaged. HE staining indicated that, db/db −/− mice’ cerebral cortex and heart tissue stained lighter, inflammatory cells infiltration, cell edema were obvious, myocardial fibers were disorder, and myocardial cells showed different degrees of degeneration. Compared with wt mice, TUNEL staining showed that there was obviously increase in db/db −/− mice cortex and heart tissue cell apoptosis. The results of immunohistochemistry and Western Blot indicated that CAIII, Beclin-1 and LC3II/I expression levels conspicuously decreased in cortex and heart tissue of db/db −/− mice, and the expression level of IL-17, NF-κB and p53 obviously increased. The carotid artery’ vascular stiffness was increased and which was probably related with formation of AS in diabetic mice. And the autophagy participated in the occurrence and development of diabetic CCD. CAIII protein might somehow be involved in the regulation of autophagy probably through affecting cell apoptosis and inflammation, but the underlying mechanism remains to be further studied.

Expression profiling of WRKY transcription factors in Spinach - Yaying Ma; Shuai Chen; Hongying Yu; Ruoyu Li; Zhicong Lin; Mingxing Cai; Min Tang; Xingtan Zhang; Ray Ming (Euphytica, 2021)

Associations between phthalic acid esters in house dust and home characteristics/living habits in a rural region of Taiwan - Chien-Che Hung; Tzu-Hsien Yu; Sailent Rizki Sari Simaremare; Chia-Jung Hsieh; Lih-Ming Yiin (Environmental Science and Pollution Research, 2021)

Correction to: Ocean acidification alters the thermal performance curves of brooded larvae from the reef coral Pocillopora damicornis - Lei Jiang; You-Fang Sun; Yu-Yang Zhang; Yuan Tian; Xin-Ming Lei; Guo-Wei Zhou; Tao Yuan; Xiang-Cheng Yuan; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Astaxanthin Ameliorates Blood Pressure in Salt-Induced Prehypertensive Rats Through ROS/MAPK/NF-κB Pathways in the Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Yan Zhang; Chen-Long Wang; Yi-Ming Lei; Jia-Yue Yu; Dong-Miao Zong; Kai-Li Liu; Dong-Dong Zhang; Ying Li; Hua Tian; Nian-Ping Zhang; et al. (Cardiovascular Toxicology, 2021)

Analysis of deformation control mechanism of prestressed anchor on jointed soft rock in large cross-section tunnel - Gan Li; Yu Hu; Si-ming Tian; Ma weibin; Hai-long Huang (Bulletin of Engineering Geology and the Environment, 2021)

Long non-coding RNA TTC28-AS1 attenuates high glucose-induced damage in HK-2 cells depending on the regulation of miR-320a/CD2AP axis - Ji Zhang; Juan Ding; Ming Yu; Fang Li; Xue Zhou; Hongxia Shuai (Genes & Genomics, 2021)

Muricauda chongwuensis sp. nov., isolated from coastal seawater of China - Ming-Xia Chen; Xiao-Yu He; He-Yang Li (Archives of Microbiology, 2021)

Optimization of immunization procedure for SWCNTs‐based subunit vaccine with mannose modification against spring viraemia of carp virus in common carp - Yu‐Ming Gong; Chen Zhang; Yang Li; Guo Chen; Gao‐Xue Wang; Bin Zhu (Journal of Fish Diseases, 2021)
Immersion vaccination of single‐walled carbon nanotubes loaded with mannose‐modified glycoprotein (SWCNTs‐MG) vaccine has been proved to be effective in preventing spring viraemia of carp virus (SVCV). Immunization procedure has immense consequence on the immune effect of the immersion vaccine. However, immunization procedure optimization for SWCNTs‐MG vaccine against SVCV has not been reported. In this study, accordingly, a full‐factor experiment was designed to optimize the immunization procedure of SWCNTs‐MG vaccine by three aspects of vaccine dose (30 mg/L, 40 mg/L and 50 mg/L), immunization density (8 fish L −1 , 24 fish L −1 and 48 fish L −1 ) and immunization time (6, 12 and 24 hr). Furthermore, we used the immunization group (A1B2C1, 30 mg/L, 24 fish L −1 and 6 hr) in the previous study as a positive control (PC) to evaluate the immunization effect optimized conditions from the expression of immune‐related genes and relative percentage survival (RPS). At 28 days post‐vaccination (DPV), common carps were intraperitoneal injected SVCV challenged test indicated that the A1B2C2 group (30 mg/L, 24 fish L −1 , 12 hr) displayed superiority of protective efficacy compare with other groups and the RPS with 77.9%, which was 15.6% higher than the PC group of RPS with 62.3%. Moreover, the expression of immune‐related genes such as IL‐10 , CD4 and MHC‐II was also significantly higher than PC group. The specific experimental flow chart is shown in Figure 1 . Conclusively, these results demonstrated that vaccine dose, immunization density and immunization time are 30 mg/L, 24 fish L −1 and 12 hr, which is the more appropriate immunization programme with juvenile carp for SWCNTs‐MG vaccine. This study provides a profitable reference for improving the immune efficiency of aquatic immersion vaccine. The experiment process and timeline chart of the present research image

Timing and magnitude of climatic extremes differentially elevate mortality but enhance recovery in a fish population - Ming‐Chih Chiu; Shih‐Hsun Chang; Yu‐Ting Yen; Lin‐Yan Liao; Hsing‐Juh Lin (Global Change Biology, 2021)
The countervailing effects of disturbances (e.g., high mortality and enhanced recovery) on population dynamics can occur through demographic processes under rapidly increasing climatic extremes. Across an extreme‐event gradient, we mechanistically demonstrated how dramatic changes in streamflow have affected the population persistence of endangered salmon in monsoonal Taiwan over a three‐decade period. Our modeling indicated that the dynamics of the age‐structured population were attributed to demographic processes, in which extensive mortality was characterized as a function of climatic extremes and vulnerability in the young stage of fish. In the stochastic simulations, we found that the extensive mortality and high proportion of large fish resulted from extreme flooding, which caused high values of postimpact population recovery. Our empirical evidence suggests that the magnitudes and timing of disturbance can explain the population persistence when facing climatic extremes and thereby challenges the understanding of the mechanistic drivers of these countervailing phenomena under changing environmental conditions.

Progress in understanding of Indian Ocean circulation, variability, air–sea exchange, and impacts on biogeochemistry - Helen E. Phillips; Amit Tandon; Ryo Furue; Raleigh Hood; Caroline C. Ummenhofer; Jessica A. Benthuysen; Viviane Menezes; Shijian Hu; Ben Webber; Alejandra Sanchez-Franks; Deepak Cherian; Emily Shroyer; et al. (Ocean Science, 2021)
Over the past decade, our understanding of the Indian Ocean has advanced through concerted efforts toward measuring the ocean circulation and air–sea exchanges, detecting changes in water masses, and linking physical processes to ecologically important variables. New circulation pathways and mechanisms have been discovered that control atmospheric and oceanic mean state and variability. This review brings together new understanding of the ocean–atmosphere system in the Indian Ocean since the last comprehensive review, describing the Indian Ocean circulation patterns, air–sea interactions, and climate variability. Coordinated international focus on the Indian Ocean has motivated the application of new technologies to deliver higher-resolution observations and models of Indian Ocean processes. As a result we are discovering the importance of small-scale processes in setting the large-scale gradients and circulation, interactions between physical and biogeochemical processes, interactions between boundary currents and the interior, and interactions between the surface and the deep ocean. A newly discovered regional climate mode in the southeast Indian Ocean, the Ningaloo Niño, has instigated more regional air–sea coupling and marine heatwave research in the global oceans. In the last decade, we have seen rapid warming of the Indian Ocean overlaid with extremes in the form of marine heatwaves. These events have motivated studies that have delivered new insight into the variability in ocean heat content and exchanges in the Indian Ocean and have highlighted the critical role of the Indian Ocean as a clearing house for anthropogenic heat. This synthesis paper reviews the advances in these areas in the last decade.

Theoretical and Numerical Analysis of Blasting Pressure of Cylindrical Shells under Internal Explosive Loading - Zhan-Feng Chen; Hui-Jie Wang; Zhiqian Sang; Wen Wang; He Yang; Wei-Ming Meng; Yu-Xing Li (Journal of Marine Science and Engineering, 2021)
Cylindrical shells are principal structural elements that are used for many purposes, such as offshore, sub-marine, and airborne structures. The nonlinear mechanics model of internal blast loading was established to predict the dynamic blast pressure of cylindrical shells. However, due to the complexity of the nonlinear mechanical model, the solution process is time-consuming. In this study, the nonlinear mechanics model of internal blast loading is linearized, and the dynamic blast pressure of cylindrical shells is solved. First, a mechanical model of cylindrical shells subjected to internal blast loading is proposed. To simplify the calculation, the internal blast loading is reduced to linearly uniform variations. Second, according to the stress function method, the dynamic blast pressure equation of cylindrical shells subjected to blast loading is derived. Third, the calculated results are compared with those of the finite element method (FEM) under different durations of dynamic pressure pulse. Finally, to reduce the errors, the dynamic blast pressure equation is further optimized. The results demonstrate that the optimized equation is in good agreement with the FEM, and is feasible to linearize the internal blast loading of cylindrical shells.

New cyclopentenoneacrylic acid derivatives from a marine-derived fungus Trichoderma atroviride H548 - Xi-Xiang Tang; Shun-Zhi Liu; Yu-Ying Sun; Feng-Ming He; Guang-Xin Xu; Mei-Juan Fang; Wu Zhen; Ying-Kun Qiu (Natural Product Research, 2021)

Loganin ameliorates depression-like behaviors of mice via modulation of serotoninergic system - Chen-Hao Pan; Cong-Yuan Xia; Yu Yan; Yan Han; Rui Shi; Jun He; Ze-Xing Wang; Yu-Ming Wang; Wei-Ku Zhang; Jie-Kun Xu (Psychopharmacology, 2021)

Development and validation of gene-specific KASP markers for YrAS2388R conferring stripe rust resistance in wheat - Yanling Hu; Xuhui Huang; Fang Wang; Yu He; Lihua Feng; Bo Jiang; Ming Hao; Shunzong Ning; Zhongwei Yuan; Jiajie Wu; Lianquan Zhang; Bihua Wu; et al. (Euphytica, 2021)

Exposure to 2,4-dichlorophenol, 2,4,6-trichlorophenol, pentachlorophenol and risk of thyroid cancer: a case-control study in China - Wan-Jun Yang; Hua-Bing Wu; Chi Zhang; Qi Zhong; Ming-Jun Hu; Jia-Liu He; Guo-Ao Li; Zhen-Yu Zhu; Jin-Liang Zhu; Huan-Huan Zhao; Han-Shuang Zhang; Fen Huang (Environmental Science and Pollution Research, 2021)

Effects of organic acids on the chemotaxis profiles and biocontrol traits of antagonistic bacterial endophytes against root-rot disease in Panax notoginseng - Li Ma; Wu-Qin Wang; Rui Shi; Xue-Mei Zhang; Xin Li; Yu-Sen Yang; Ming He Mo (Antonie van Leeuwenhoek, 2021)

Pseudomonas nanhaiensis sp. nov., a lipase-producing bacterium isolated from deep-sea sediment of the South China Sea - Yu Pang; Yage Zhang; Mengru Chen; Wei Lu; Ming Chen; Yongliang Yan; Min Lin; Wei Zhang; Zhengfu Zhou (Antonie van Leeuwenhoek, 2021)

Vertical Nitrate Flux Induced by Kelvin–Helmholtz Billows Over a Seamount in the Kuroshio - Cristy S. Acabado; Yu-Hsin Cheng; Ming-Huei Chang; Chung-Chi Chen (Frontiers in Marine Science, 2021)
Kelvin–Helmholtz (KH) billows can facilitate microscale turbulent mixing around seamounts in the Kuroshio. This study sought to describe the influence of billow intensity (i.e., “intermittent and small” and “steady and large” billows) on vertical nitrate fluxes. KH billows led to turbulent kinetic energy dissipation rates [ε = O (10 –7 to 10 –6 ) W kg –1 ] and eddy diffusivities [K ρ = O (10 –4 to 10 –3 ) m 2 s –1 ] that were significantly stronger than those outside the billow depths. The mean nitrate flux estimated using K ρ in the billow depths had a maximal value of 10.0 mmol m –2 day –1 , which was much higher than estimates for the open ocean. The nitrate flux associated with the shallow KH billows at two vertical levels contributed to enrich the subsurface phytoplankton maximum, while the deeper billows closer to the summit were found to induce a large amount of nitrate flux from the deeper to the subsurface water. This study showed that KH billows make important contributions to seamount ecosystems, particularly in the cycling and vertical mixing of nutrients to make them available for potential downstream transport.

Impacts of pH on the Fitness and Immune System of Pacific White Shrimp - Veran Weerathunga; Wei-Jen Huang; Sam Dupont; Hsueh-Han Hsieh; Nathangi Piyawardhana; Fei-Ling Yuan; Jhe-Syuan Liao; Chia-Yu Lai; Wei-Ming Chen; Chin-Chang Hung (Frontiers in Marine Science, 2021)
The atmospheric partial pressure of CO 2 ( p CO 2 ) has been increasing dramatically since the beginning of the industrial revolution and about 30% of the CO 2 produced by anthropogenic activities was absorbed by the ocean. This led to a perturbation of the seawater carbonate chemistry resulting in a decrease of the average surface ocean pH by 0.1 and termed ocean acidification (OA). Projections suggest that p CO 2 may reach 900 μatm by the end of the twenty-first century lowering the average pH of the surface ocean by 0.4 units. The negative impacts of OA on many species of marine invertebrates such as mollusks, echinoderms, and crustaceans are well documented. However, less attention has been paid to the impacts of low pH on fitness and immune system in crustaceans. Here, we exposed Pacific white shrimps to 3 different pHs (nominal pH 8.0, 7.9, and 7.6) over a 100-days experiment. We found that, even though there were no significant effects on fitness parameters (survival, growth and allometries between length and weight), some immune markers were modified under low pH. A significant decrease in total hemocyte count and phenoloxidase activity was observed in shrimps exposed to pH 7.6 as compared to pH 8.0; and phagocytosis rate significantly decreased with decreasing pH. A significant increase in superoxide production was also observed at pH 7.6 as compared to pH 8.0. All these results suggest that a 100-days exposure to pH 7.6 did not have a direct effect on fitness but lead to a modulation of the immune response.

Activation of the Hippocampal LXRβ Improves Sleep-Deprived Cognitive Impairment by Inhibiting Neuroinflammation - Chen Qiu; Min Wang; Wen Yu; Zheng Rong; He-Sheng Zheng; Ting Sun; Shui-Bing Liu; Ming-Gao Zhao; Yu-Mei Wu (Molecular Neurobiology, 2021)

Updated taxonomy of Chinese Phylloporus (Boletaceae, Boletales): six new taxa and four redescribed species - Lu-Ling Wu; Zhi-Qun Liang; Ming-Sheng Su; Yu-Guang Fan; Ping Zhang; Shuai Jiang; Yan-Liu Chen; Yan-Jia Hao; Nian-Kai Zeng (Mycological Progress, 2021)

Influences and mechanisms of nanoparticles on pentachloronitrobenzene accumulation by earthworms - Ming Li; Guanghui Xu; Na Guo; Na Zheng; Weihua Dong; Xiao Li; Yong Yu (Environmental Science and Pollution Research, 2021)

Ocean acidification alters the thermal performance curves of brooded larvae from the reef coral Pocillopora damicornis - Lei Jiang; You-Fang Sun; Yu-Yang Zhang; Yuan Tian; Xin-Ming Lei; Guo-Wei Zhou; Tao Yuan; Xiang-Cheng Yuan; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Plasticity of symbiont acquisition in new recruits of the massive coral Platygyra daedalea under ocean warming and acidification - Lei Jiang; Guo-Wei Zhou; Yu-Yang Zhang; Xin-Ming Lei; Tao Yuan; Ming-Lan Guo; Xiang-Cheng Yuan; Jian-Sheng Lian; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Inhibition of Maternal c-Src Ameliorates the Male Offspring Hypertension by Suppressing Inflammation and Neurotransmitters in the Paraventricular Nucleus - Qing Su; Xiao-Jing Yu; Qing Yang; Xiao-Min Wang; Wen-Jie Xia; Hong-Bao Li; Kai-Li Liu; Qiu-Yue Yi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Sandaracinobacteroides hominis gen. nov., sp. nov., isolated from human skin - Ping-Hua Qu; Hai-Min Luo; Jun-Hui Feng; Song Li; Cha Chen; Lei Dong; Yu-Zhen Ming; Wen-Jun Li; Ying Lin (Archives of Microbiology, 2021)

The microstructure and mechanical property of tailings and its application in artificial concrete - Fan Yu-yun; Wang Xi; Jiang Ming-wei; Liu Xing-quan (Arabian Journal of Geosciences, 2021)

Incorporating Species-Conditional Co-Occurrence When Selecting Indicator Species to Monitor Restoration after Mangrove Removal from the Siangshan Wetland, Taiwan - Ta-Jen Chu; Chun-Han Shih; Yu-Ming Lu; Yi-Jia Shih; Jia-Qiao Wang; Liang-Ming Huang (Journal of Marine Science and Engineering, 2021)
This paper presents an approach for incorporating species-conditional co-occurrence into models used for the selection of marine indicator species. Mangrove invasion within the Siangshan Wetland in Hsinchu, Taiwan, has changed the original structures and functions of habitats for benthic organisms. The Hsinchu City Government ran a large-scale mangrove removal project from October 2015 to March 2016 to restore the wetland. From October 2015 to September 2016, we investigated the biological effects of mangrove removal on benthic crabs and their adjacent habitats. Density, number of species, Shannon–Weaver index (H′) and Palou’s evenness index (J′) were calculated and compared between mangrove and non-mangrove regions. The results showed that values for these attributes in the non-mangrove regions were higher than those of the mangrove regions. After mangrove removal, species returned to their original habitats and the related density increased significantly. Using conditional co-occurrence algorithms, we identified five indicator species (Mictyris brevidactylus, Macrophthalmus banzai, Uca arcuata, Uca lacteal and Uca borealis) with high co-occurrence probabilities, whose population responses provided direct evidence of the benefits of mangrove removal for wetland restoration. The results indicate that mangrove removal is an appropriate habitat rehabilitation strategy for benthic organisms, and that the chosen indicator species may provide valuable ecological information for coastal managers seeking to control the spread of mangroves.

Structure–activity relationship studies on Pd176252 derivatives leading to discovery of novel GRP receptor antagonist with potent anticancer activity - Ming-jun Yu; Chao Li; Meng He; Yu-ting Zhu; Rui Yang; Sheng-song Deng; Xiao-ming Meng; Ri-sheng Yao (Medicinal Chemistry Research, 2021)

A new monoterpene-lactone with neuroprotective activity from corn silk - Wei-Yu Zhou; Tian-Ming Lv; Zi-Lin Hou; Ming Bai; Bin Lin; Xiao-Xiao Huang; Shao-Jiang Song (Natural Product Research, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Arabidopsis AtPRP17 functions in embryo development by regulating embryonic patterning - Dong Jie Shao; Yi Ming Wei; Zhong Qing Yu; Xinren Dai; Xin-Qi Gao (Planta, 2021)

Pinocembrin Promotes OPC Differentiation and Remyelination via the mTOR Signaling Pathway - Qi Shao; Ming Zhao; Wenwen Pei; Yingyan Pu; Mingdong Liu; Weili Liu; Zhongwang Yu; Kefu Chen; Hong Liu; Benqiang Deng; Li Cao (Neuroscience Bulletin, 2021)

The ATP Level in the mPFC Mediates the Antidepressant Effect of Calorie Restriction - Qian Wang; Ying Kong; Song Lin; Ding-Yu Wu; Jian Hu; Lang Huang; Wen-Si Zang; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice - Thomas H Lee; Ahadullah; Brian R Christie; Kangguang Lin; Parco Ming-fai Siu; Li Zhang; Ti-fei Yuan; Pragya Komal; Aimin Xu; Kwok-fai So; Suk-yu Yau (Molecular Neurobiology, 2021)
Administration of exercise mimetic drugs could be a novel therapeutic approach to combat comorbid neurodegeneration and metabolic syndromes. Adiponectin is an adipocyte-secreted hormone. In addition to its antidiabetic effect, adiponectin mediates the antidepressant effect of physical exercise associated with adult hippocampal neurogenesis. The antidiabetic effect of the adiponectin receptor agonist AdipoRon has been demonstrated, but its potential pro-cognitive and neurotrophic effects in the hippocampus under diabetic condition are still unclear. This study reported that chronic AdipoRon treatment for 2 weeks improved hippocampal-dependent spatial recognition memory in streptozotocin-induced diabetic mice. Besides, AdipoRon treatment increased progenitor cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (DG) of diabetic mice. Furthermore, AdipoRon treatment significantly increased dendritic complexity, spine density, and N -methyl-D-aspartate receptor-dependent long-term potentiation (LTP) in the dentate region, and increased BDNF levels in the DG of diabetic mice. AdipoRon treatment activated AMPK/PGC-1α signalling in the DG, whereas increases in cell proliferation and LTP were not observed when PGC-1α signalling was pharmacologically inhibited. In sum, chronic AdipoRon treatment partially mimics the benefits of physical exercise for learning and memory and hippocampal neuroplasticity in the diabetic brain. The results suggested that AdipoRon could be a potential physical exercise mimetic to improve hippocampal plasticity and hence rescue learning and memory impairment typically associated with diabetes.

Integrated analysis of mRNA and long non-coding RNA expression profiles reveals the potential roles of lncRNA-mRNA network in carp macrophage immune regulation - Shuai Liu; Ting Yu; Yuanyuan Zhang; Chenyuan Pan; Ling Cai; Ming Yang (In Vitro Cellular & Developmental Biology - Animal, 2021)

Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines in Hypothalamic Paraventricular Nucleus - Hong-Li Gao; Xiao-Jing Yu; Han-Bo Hu; Qian-Wen Yang; Kai-Li Liu; Yan-Mei Chen; Yan Zhang; Dong-Dong Zhang; Hua Tian; Guo-Qing Zhu; Jie Qi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Based on G-Series Mouse TH17 Array Study the Effect of Fluoride on C2C12 Cells Cytokines Expression - Shi-quan Zhu; Bian-hua Zhou; Pan-pan Tan; Jun Chai; Ya-ming Yu; Hong-wei Wang (Biological Trace Element Research, 2021)

Dynamic Response of a Non-Darcian Seepage System in the Broken Coal of a Karst Collapse Pillar - Tian-jun Zhang; Ming-kun Pang; Xiang Ji; Hong-yu Pan (Mine Water and the Environment, 2021)

Inactivation and Removal Technologies for Algal-Bloom Control: Advances and Challenges - Ming-ming Zhan; Pei-rui Liu; Xiao-ya Liu; Yu Hong; Xing Xie (Current Pollution Reports, 2021)

Detrimental impact of hypoxia on the mortality, growth, reproduction, and enzyme activities of planktonic mysid Neomysis awatschensis - Qiao-ning Wang; Xiao-dong Li; Tian Yan; Jing-jing Song; Ren-cheng Yu; Ming-jiang Zhou (Aquatic Ecology, 2021)

Anti-Inflammatory and anti-proliferative oleanane-type triterpene glycosides from the vine of Momordica cochinchinensis - Hung-Tse Huang; Yu-Chi Lin; Li-Jie Zhang; Chia-Ching Liaw; Hsin-Yen Chen; Ming-Tung Hsueh; Yao-Haur Kuo (Natural Product Research, 2021)

A new p -terphenyl derivative from the fruiting bodies of Sarcodon imbricatus (L.) P. Karst - Feng-Ming Zhang; Yue-Hu Wang; Ping Zhao; Fu-Qiang Yu (Natural Product Research, 2021)

Correction to: MiR-26a regulated adipogenic differentiation of ADSCs induced by insulin through CDK5/FOXC2 pathway - Xu-Xiang Zhang; Yu-Ming Wang; Yan-Dan Su; Fan Zuo; Bin Wu; Xin Nian (Molecular and Cellular Biochemistry, 2021)

Synthesis and biological evaluation of novel 1,3-diphenylurea quinoxaline derivatives as potent anticancer agents - Gui-Zhen Li; Xi-Lin Ouyang; Zu-Yu Mo; Yao Gu; Xiao-Lin Cao; Li Yang; Hai-Tao Tang; Ying-Ming Pan (Medicinal Chemistry Research, 2021)

Application of Plant Print Identification Technology in Salt-resistant Soybean Breeding - Yan Li; Xia Li; Zi-qi Chen; Ying Ma; Guang-yu Yang; Ying Zhang; Ming-chun Sun; Li-hong Zhang; Jin-meng Chu; Jing-mei Lu; Jun Zhu; Ji-hong You (Journal of Plant Growth Regulation, 2021)

Risk of two common glandular cell-type cancers (breast and colorectal cancers) in Chinese occupational chefs: a nationwide ecological study in Taiwan - Pei-Chen Lin; Chiung‑Yu Peng; Chih‑Hong Pan; Jui-Ying Lee; Tusty-Jiuan Hsieh; Yun-Shiuan Chuang; Robert J. Turesky; Chia-Fang Wu; Ming-Tsang Wu (International Archives of Occupational and Environmental Health, 2021)

Gas-phase isopropanol degradation by nonthermal plasma combined with Mn-Cu/-Al2O3 - Ken-Lin Chang; Yu-Chieh Lin; Ming-Ze Qiu; Chun-Wei Tu; Chih-Ping Chang; Jhong-Lin Wu; Yung-Chang Lin; Chien-Kuei Chang (Environmental Science and Pollution Research, 2021)

Flexible reconfiguration of functional brain networks as a potential neural mechanism of creativity - Junchao Li; Natasza Orlov; Zengjian Wang; Bingqing Jiao; Yibo Wang; Huawei Xu; Hui Yang; Yingying Huang; Yan Sun; Peng Zhang; Rengui Yu; Ming Liu; et al. (Brain Imaging and Behavior, 2021)

OSL chronology of a Palaeolithic site in a humid subtropical mountainous area of southeast China - Jian-hui Jin; Xiao-yang Wang; Zhen-yu Zhou; Yun-ming Huang; Xue-chun Fan; Xin-xin Zuo; Zhi-zhong Li; Zhi-yong Ling; Yong-qing Ren; Shu-tong Li (Journal of Mountain Science, 2021)

Efficacy of Entomopathogenic fungus Aspergillus nomius against Dolichoderus thoracicus - Wei-Jiun Lin; Ming-Chung Chiu; Chung-Chi Lin; Yuan-Kai Chung; Jui-Yu Chou (BioControl, 2021)

Rapid differential detection of subtype H1 and H3 swine influenza viruses using a TaqMan-MGB-based duplex one-step real-time RT-PCR assay - Kaibiao Chen; Ming Kong; Jiao Liu; Jun Jiao; Zixiong Zeng; Liwei Shi; Xinxin Bu; Yayao Yan; Yu Chen; Ruyi Gao; Xiaowen Liu; Xiaoquan Wang; et al. (Archives of Virology, 2021)

Enrichment of marine productivity utilizing steelmaking slag: managing conflicting stakeholders’ interests in Taiwan - Yung-Sheng Chen; Ming-Sheng Ko; Yu-Cheng Wang; Ping Chen; Ta-Kang Liu (Aquaculture International, 2021)

Anthropogenic disturbances caused declines in the wetland area and carbon pool in China during the last four decades - Mingzhi Lu; Yuanchun Zou; Qilei Xun; Zicheng Yu; Ming Jiang; Lianxi Sheng; Xianguo Lu; Deli Wang (Global Change Biology, 2021)
Wetlands are among the natural ecosystems with the highest soil carbon stocks on Earth. However, how anthropogenic disturbances have impacted the quantity and distribution of wetland carbon pool in China is not well understood. Here we used a comprehensive countrywide wetland inventory and Landsat 8 data to document the spatial patterns in China's wetland areas and carbon pools and to understand the underlying causes of their changes from the 1980s to 2010s. We found that the wetland area and carbon pool have decreased from 4.11 × 10 5 km 2 and 15.2 Pg C in the 1980s to 2.14 × 10 5 km 2 and 7.6 Pg C in the 2010s, respectively. Using the human influence index (HII) as a quantitative measure of anthropogenic disturbance intensity, we found a positive relationship between the HII values and wetland decreases in many regions and across China as a whole—which have increased 17% during the time period—indicating that anthropogenic disturbances have been a major factor causing wetland destruction in recent decades. This study provides new evidence for recent changes in China's wetland carbon pool and emphasizes the importance of mitigating anthropogenic disturbances for wetland conservation.

Two new pregnane steroidal glycosides from Cynanchum taihangense - Yu-Bo Wang; Shan-Shan Su; Ming-Xu Tang; Dan Zhao; Gang Chen; Shao-Fei Chen; Hai-Feng Wang; Yue-Hu Pei (Natural Product Research, 2021)

Prenylated xanthones and biphenyls from Garcinia esculenta with antistaphylococcal activity - Dan Zheng; Hong Zhang; Jia-Ming Jiang; Yu-Yu Chen; Shi-Jie Wan; Zhi-Xiu Lin; Hong-Xi Xu (Natural Product Research, 2021)

A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication - Ran Li; Peng Yang; Ming Li; Wenwen Fang; Xiangpeng Yue; Hojjat Asadollahpour Nanaei; Shangquan Gan; Duo Du; Yudong Cai; Xuelei Dai; Qimeng Yang; Chunna Cao; et al. (Science China Life Sciences, 2021)

Calcineurin inhibitor–associated new-onset diabetes mellitus in chronic kidney disease treatment: a 4-year single-center cross-sectional study in China - Pan Kun-ming; Chen Can; Xu Qing; Wu Wei; Lv Qian-zhou; Li Xiao-yu (European Journal of Clinical Pharmacology, 2021)

Study on the correlation of bisphenol A exposure, pro-inflammatory gene expression, and C-reactive protein with potential cardiovascular disease symptoms in young adults - Chao-Ming Tsen; Jia-Hong Liu; Da-Peng Yang; How-Ran Chao; Jyh-Larng Chen; Wei-Chun Chou; Yi-Chen Ho; Chun-Yu Chuang (Environmental Science and Pollution Research, 2021)

Acute exposure to microcystin-LR induces hepatopancreas toxicity in the Chinese mitten crab (Eriocheir sinensis) - Cheng Chi; Xia-Wei Yu; Cai-Yan Zhang; Jia-Dai Liu; Ming-Wen Ye; Ding-Dong Zhang; Wen-Bin Liu (Archives of Toxicology, 2021)

Aestuariimicrobium ganziense sp. nov., a new Gram-positive bacterium isolated from soil in the Ganzi Tibetan autonomous prefecture, China - Yu Geng; Jiang-Yuan Zhao; Hui-Ren Yuan; Le-Le Li; Meng-Liang Wen; Ming-Gang Li; Shu-Kun Tang (Archives of Microbiology, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

Tamlana haliotis sp. nov., isolated from the gut of the abalone Haliotis rubra - Wen-Rui Cao; Bang-Tao Liu; Xun-Ke Sun; Yuan-Yuan Sun; Ming-Yu Jiang; Zong-Jun Du (Archives of Microbiology, 2021)

In-Situ Seawater Gamma Spectrometry with LaBr3 Detector at a Nuclear Power Plant Outlet - Daowei Dou; Zhi Zeng; Wen Yu; Ming Zeng; Wu Men; Feng Lin; Hao Ma; Jianping Cheng; Junli Li (Journal of Marine Science and Engineering, 2021)
In a nuclear emergency, the application of in situ spectrometers for monitoring environmental radioactivity is significantly important, as information on the type and activity of radionuclides released from the accident can be obtained quickly. However, in emergency environmental radiological monitoring, a balance between energy resolution and detecting efficiency must be considered in selecting an appropriate detector. In this study, in situ gamma spectrometry was conducted with the LaBr3 detector to determine the radioactivity of seawater at the discharging outlet of a coastal nuclear power plant in southeast China. The results show that the LaBr3 scintillator has excellent energy resolution and detection efficiency, making it a promising detector for emergency monitoring.

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

Phenylpropanoids and lignoids from the whole plant of Vaccinium emarginatum and their cytotoxicity against prostate cancer cells - Ping-Chen Tu; Yu-Chia Liang; Ming-Ching Kao; Louis Kuoping Chao; Mei-Hwei Tseng; Te-Ling Lu; Ping-Jyun Sung; Yueh-Hsiung Kuo (Natural Product Research, 2021)

An underlying mechanism of qE deficiency in marine angiosperm Zostera marina - Wei Zhao; Quan Sheng Zhang; Ying Tan; Zhe Liu; Ming Yu Ma; Meng Xin Wang; Cheng Ying Luo (Photosynthesis Research, 2021)

Correction to: Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain - Shao-Ming Wang; Nino Goguadze; Yuriko Kimura; Yuko Yasui; Bin Pan; Tzu-Yun Wang; Yoki Nakamura; Yu-Ting Lin; Quinn H. Hogan; Katherine L. Wilson; Tsung-Ping Su; Hsiang-en Wu (Molecular Neurobiology, 2021)
A correction to this paper has been published: 10.1007/s12035-021-02310-3

Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain - Shao-Ming Wang; Nino Goguadze; Yuriko Kimura; Yuko Yasui; Bin Pan; Tzu-Yun Wang; Yoki Nakamura; Yu-Ting Lin; Quinn H. Hogan; Katherine L. Wilson; Tsung-Ping Su; Hsiang-en Wu (Molecular Neurobiology, 2021)
Sigma-1 receptors (Sig-1Rs) are endoplasmic reticulum (ER) chaperones implicated in neuropathic pain. Here we examine if the Sig-1R may relate to neuropathic pain at the level of dorsal root ganglia (DRG). We focus on the neuronal excitability of DRG in a “spare nerve injury” (SNI) model of neuropathic pain in rats and find that Sig-1Rs likely contribute to the genesis of DRG neuronal excitability by decreasing the protein level of voltage-gated Cav2.2 as a translational inhibitor of mRNA. Specifically, during SNI, Sig-1Rs translocate from ER to the nuclear envelope via a trafficking protein Sec61β. At the nucleus, the Sig-1R interacts with cFos and binds to the promoter of 4E-BP1, leading to an upregulation of 4E-BP1 that binds and prevents eIF4E from initiating the mRNA translation for Cav2.2. Interestingly, in Sig-1R knockout HEK cells, Cav2.2 is upregulated. In accordance with those findings, we find that intra-DRG injection of Sig-1R agonist (+)pentazocine increases frequency of action potentials via regulation of voltage-gated Ca2+ channels. Conversely, intra-DRG injection of Sig-1R antagonist BD1047 attenuates neuropathic pain. Hence, we discover that the Sig-1R chaperone causes neuropathic pain indirectly as a translational inhibitor.

Overexpression of T-type calcium channel Cav3.1 in oral squamous cell carcinoma: association with proliferation and anti-apoptotic activity - Rui-Fang Li; Qi-Wen Man; Jin-Yuan Liu; Yue-Yu Zheng; Xin Gao; Hai-Ming Liu (Journal of Molecular Histology, 2021)

Environmental microorganism classification using optimized deep learning model - Chih-Ming Liang; Chun-Chi Lai; Szu-Hong Wang; Yu-Hao Lin (Environmental Science and Pollution Research, 2021)

Performance of permeable pavement systems on stormwater permeability and pollutant removal - Zhiji Yu; Huihui Gan; Ming Xiao; Biao Huang; David Z. Zhu; Zheyun Zhang; Huanyan Wang; Yongliang Lin; Yonglong Hou; Shuai Peng; Wei Zhang (Environmental Science and Pollution Research, 2021)

Nrf1 Knock-Down in the Hypothalamic Paraventricular Nucleus Alleviates Hypertension Through Intervention of Superoxide Production-Removal Balance and Mitochondrial Function - Ying Li; Xiao-Jing Yu; Tong Xiao; Hong-Li Chi; Guo-Qing Zhu; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

A transcription factor TaTCP20 regulates the expression of Ppd-D1b in common wheat - Fan Wei; Tianqi Song; Jianfei Zhou; Jie Cheng; Ruibo Li; Ming Yu; Yunrui Zhang; Yang Yu; Bo Zhang; Xiaoke Zhang (Plant Biotechnology Reports, 2021)

Characterization of Water Quality in Xiao Xingkai Lake: Implications for Trophic Status and Management - Shuling Yu; Xiaoyu Li; Bolong Wen; Guoshuang Chen; Anne Hartleyc; Ming Jiang; Xiujun Li (Chinese Geographical Science, 2021)

Composition and co-occurrence patterns of Phragmites australis rhizosphere bacterial community - Siwen Hu; Rujia He; Wanjie Wang; Dayong Zhao; Jin Zeng; Rui Huang; Ming Duan; Zhongbo Yu (Aquatic Ecology, 2021)

First observation of conjoined twins in Oryzias melastigma - Dao De Yu; Hai Yi Wu; Zhi Peng Zhang; Wen Dan Chi; Kai Kai Liu; Ming Liu; Ming Qi Wang; Jing Jing Song (Journal of Fish Diseases, 2021)

Computed Tomography Super-Resolution Using a Generative Adversarial Network in Bronchoscopy: A Clinical Feasibility Study - Heng-sheng Chao; Tsu-Hui Shiao; Chung-Wei Chou; Fang-Chi Lin; Yu-Te Wu; Der-Ming Liou (Journal of Medical and Biological Engineering, 2021)

Anti-inflammatory glycosides from the roots of Paeonia intermedia C. A. Meyer - Liang Yu; Ling-Juan Zhu; An-Hua Wang; Yu Qin; Xue Zhang; Jing-Ming Jia; Xin-Sheng Yao (Natural Product Research, 2021)

Study on Microwave Heating Order and Electromagnetic Characteristics of Copper and Gold Ores - Feng Lin; Xia-Ting Feng; Gao-Ming Lu; Xiang-Xin Su; Shi-Ping Li; Jiu-yu Zhang (Rock Mechanics and Rock Engineering, 2021)

Association between functional brain alterations and neuropsychological scales in male chronic smokers using resting-state fMRI - Jun-Cheng Weng; Shih-Yu Huang; Ming-Shih Lee; Ming-Chou Ho (Psychopharmacology, 2021)

QTL mapping of the genetic basis of stem diameter in soybean - Chong-Yuan Sun; Yu-Ming Yang; Lin Jia; Xiao-Qian Liu; Huan-Qing Xu; Hai-Yan Lv; Zhong-Wen Huang; Dan Zhang (Planta, 2021)

Amygdala-based Functional Network Reveals Dissociated Neural Correlates of Consensual and Idiosyncratic Emotional Movie Experiences - Lin Cui; Bingbing Guo; Dan Zhao; Jiaxin Li; Yu Luo; Ming Meng (Neuroscience Bulletin, 2021)

Synthesis and antitumor evaluation of (aryl)methyl-amine derivatives of dehydroabietic acid-based B ring-fused-thiazole as potential PI3K/AKT/mTOR signaling pathway inhibitors - Nai-Yuan Chen; Yu-Lan Xie; Guo-Dong Lu; Fang Ye; Xin-Yu Li; Yu-Wen Huang; Ming-Li Huang; Tie-Yu Chen; Cui-Ping Li (Molecular Diversity, 2021)

Diversity, metabolism and cultivation of archaea in mangrove ecosystems - Cui-Jing Zhang; Yu-Lian Chen; Yi-Hua Sun; Jie Pan; Ming-Wei Cai; Meng Li (Marine Life Science & Technology, 2021)

RETRACTED ARTICLE: Two Metal Complexes: Selective Detection of Fe3+ Ion and Promotion Activity on Mesenchymal Stem Cells Differentiate Into Vascular Endothelial Cells - Qin-Ming Zhao; Zhong-You Xu; Hui-Peng Zhu; Yu-Xiang He; Mo Wang (Journal of Fluorescence, 2021)

Ruegeria haliotis sp. nov., Isolated from the Gut of the Abalone Haliotis rubra - Wen-Rui Cao; Dan-Dan Shang; Bang-Tao Liu; Yi-Hao Hu; Xun-Ke Sun; Yuan-Yuan Sun; Ming-Yu Jiang; Zong-Jun Du (Current Microbiology, 2021)

Analyzing Liver Surface Indentation for In Vivo Refinement of Tumor Location in Minimally Invasive Surgery - Yingqiao Yang; Kai-Leung Yung; Tin Wai Robert Hung; Kai-Ming Yu (Annals of Biomedical Engineering, 2021)
Manual palpation to update the position of subsurface tumor(s) is a normal practice in open surgery, but is not possible through the small incisions of minimally invasive surgery (MIS). This paper proposes a method that has the potential to use a simple constant-force indenter and the existing laparoscopic camera for tumor location refinement in MIS. The indenter floats with organ movement to generate a static surface deformation on the soft tissue, resolving problems of previous studies that require complicated measurement of force and displacement during indentation. By analyzing the deformation profile, we can intraoperatively update the tumor’s location in real-time. Indentation experiments were conducted on healthy and “diseased” porcine liver specimens to obtain the deformation surrounding the indenter site. An inverse finite element (FE) algorithm was developed to determine the optimal material parameters of the healthy liver tissue. With these parameters, a computational model of tumorous tissue was constructed to quantitatively evaluate the effects of the tumor location on the induced deformation. By relating the experimental data from the “diseased” liver specimen to the computational results, we estimated the radial distance between the tumor and the indenter, as well as the angular position of the tumor relative to the indenter.

Immunity improvement and gut microbiota remodeling of mice by wheat germ globulin - Guanghai Yu; Xiaoguo Ji; Jihong Huang; Aimei Liao; Long Pan; Yinchen Hou; Ming Hui; Weiyun Guo (World Journal of Microbiology and Biotechnology, 2021)

Abundance-weighted plant functional trait variation differs between terrestrial and wetland habitats along wide climatic gradients - Yu-Kun Hu; Guo-Fang Liu; Xu Pan; Yao-Bin Song; Ming Dong; Johannes H. C. Cornelissen (Science China Life Sciences, 2021)

MiR-26a regulated adipogenic differentiation of ADSCs induced by insulin through CDK5/FOXC2 pathway - Xu-Xiang Zhang; Yu-Ming Wang; Yan-Dan Su; Fan Zuo; Bin Wu; Xin Nian (Molecular and Cellular Biochemistry, 2021)

EEG-Based Anxious States Classification Using Affective BCI-Based Closed Neurofeedback System - Chao Chen; Xuecong Yu; Abdelkader Nasreddine Belkacem; Lin Lu; Penghai Li; Zufeng Zhang; Xiaotian Wang; Wenjun Tan; Qiang Gao; Duk Shin; Changming Wang; Sha Sha; et al. (Journal of Medical and Biological Engineering, 2021)

Overlying Strata Structure Evolution and Engineering Practice Based on the Mining of Lower Liberating Seam in Deep Bursting Coal Seam Group - Ming-tao Gao; Zhen-qi Song; Wei-bo Yu; Hui-qiang Duan; Heng-qi Xin; Jian-quan Tang (Geotechnical and Geological Engineering, 2021)

The spatial distribution characteristics of coseismic landslides triggered by the Ms7.0 Lushan earthquake and Ms7.0 Jiuzhaigou earthquake in southwest China - Ming Chang; Peng Cui; Lu Xu; Yu Zhou (Environmental Science and Pollution Research, 2021)

Biotransformation of Phlorizin by Eurotium cristatum to Increase the Antioxidant and Antibacterial Activity of Docynia indica Leaves - Jie Xie; Jiang Chen; Xue-ran Mei; Ming-jun Zhu; Xue-li Li; Juan Du; Xiao-yu Zhang (Current Microbiology, 2021)

Marinobacter shengliensis subsp. alexandrii Subsp. Nov., Isolated from Cultivable Phycosphere Microbiota of Highly Toxic Dinoflagellate Alexandrium catenella LZT09 and Description of Marinobacter shengliensis Subsp. shengliensis Subsp. Nov - Xi Yang; Rong Xiang; Nurhezreen Md Iqbal; Yu-Han Duan; Xiao-Ai Zhang; Lei Wang; Lin-Zeng Yu; Jia-Zhou Li; Ming-Fei Sun; Qiao Yang; Chun-Tian Zheng; Shen-Quan Liao (Current Microbiology, 2021)

Correction to: Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Bai; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Ba; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

The changes of brain functional networks in young adult smokers based on independent component analysis - XianFu Wang; Ting Xue; Fang Dong; Yangding Li; Dongdong Xie; Chang Liu; Ming Zhang; Yanzhi Bi; Kai Yuan; Dahua Yu (Brain Imaging and Behavior, 2021)

Carbon isotope variations of modern soils in the eastern margin of the Tibetan Plateau and their controlling factors - Lin Qi; Yan-song Qiao; Zong-xiu Liu; Sha-sha Peng; Yu Cheng; Yan Wang; Xu-jiao Zhang; Ming-zhong Tian; Shuai-bin Yang; Wen-bin Bai (Journal of Mountain Science, 2021)

miR-491-3p is Downregulated in Retinoblastoma and Inhibit Tumor Cells Growth and Metastasis by Targeting SNN - Yang Hu; Ming Zhao; Li Li; Jie Ding; Yu-Min Gui; Tan-Wei Wei (Biochemical Genetics, 2021)
Retinoblastoma (Rb) is the most common pediatric malignant tumor of the eyes. Previous studies demonstrated that miR-491-3p is downregulated in various cancers. However, its function in Rb remains unknown. A total of 15 pairs of primary Rb tissues and adjacent noncancerous tissues were collected. Quantitative real-time PCR (qRT-PCR) was used to investigate the expression profiles of miR-491-3p. qRT-PCR, western blotting and in situ immunocytochemistry were performed to investigate the expression profiles of epithelial–mesenchymal transition-related proteins (E-cadherin, Vimentin and N-cadherin) in Rb tissues and Rb cell lines as well as cell morphology. Cell proliferation was estimated by MTS and colony formation assays. Apoptosis was determined by FACS, cell migration and invasion were analyzed using transwell chambers. MiR-491-3p’s target genes were predicted using target gene prediction databases. The interplay between miR-491-3p and SNN was evaluated through dual luciferase reporter gene assay. MiR-491-3p was significantly downregulated in mixed collection of 15 pairs of Rb tissues and Rb cell lines. Overexpression of miR-491-3p enhanced apoptosis, and significantly suppressed proliferation, migration and invasion of Rb cells. In contrast, the present of miR-491-3p inhibitor showed reversed results which apoptosis decreased, while cell proliferation of ARPE-19 cells increased. In addition, miR-491-3p increased the expression of E-cadherin, and dramatically decreased the expression of Vimentin and N-cadherin in Rb tissues and Rb cell lines, noticeable changes in morphology, too, as cells became less cohesive and more adhering. We found out that SNN was the pairing target of miR-491-3p and result showed that miR-491-3p and SNN interacted with each other. We also found out that the effects of miR-491-3p were in Rb cells were almost entirely canceled out at the overexpression of SNN. Our findings collectively suggest that miR-491-3p is an important tumor suppressor in Rb, which inhibits tumor growth and metastasis in Rb. These implicate it may be explored as a new therapeutic target in Rb.

Air permeability of biochar-amended clay cover - Ming-Yu Li; Wen-Jing Sun; Ye-Jiao Wang; De-An Sun; Yun-Zhi Tan (Arabian Journal of Geosciences, 2021)

Thermaurantiacus tibetensis gen. nov., sp. nov., a novel moderately thermophilic bacterium isolated from hot spring microbial mat in Tibet - Yu-Zhen Ming; Lan Liu; Ai-Ping Lv; Wen-Dong Xian; Ze-Tao Liu; Meng-Meng Li; Jian-Yu Jiao; Bao-Zhu Fang; Wen-Jun Li (Antonie van Leeuwenhoek, 2021)

Western North Pacific Tropical Cyclone Database Created by the China Meteorological Administration - Xiaoqin Lu; Hui Yu; Ming Ying; Bingke Zhao; Shuai Zhang; Limin Lin; Lina Bai; Rijin Wan (Advances in Atmospheric Sciences, 2021)
This paper describes the access to, and the content, characteristics, and potential applications of the tropical cyclone (TC) database that is maintained and actively developed by the China Meteorological Administration, with the aim of facilitating its use in scientific research and operational services. This database records data relating to all TCs that have passed through the western North Pacific (WNP) and South China Sea (SCS) since 1949. TC data collection has expanded over recent decades via continuous TC monitoring using remote sensing and specialized field detection techniques, allowing collation of a multi-source TC database for the WNP and SCS that covers a long period, with wide coverage and many observational elements. This database now comprises a wide variety of information related to TCs, such as historical or real-time locations (i.e., best track and landfall), intensity, dynamic and thermal structures, wind strengths, precipitation amounts, and frequency. This database will support ongoing research into the processes and patterns associated with TC climatic activity and TC forecasting.

An Insight into the Excavation-Induced Stress Paths on Mechanical Response of Weak Interlayer Zone in Underground Cavern Under High Geostress - Shu-Qian Duan; Quan Jiang; Guo-Feng Liu; Jie-Cheng Xiong; Po Gao; Ding-Ping Xu; Ming-Yu Li (Rock Mechanics and Rock Engineering, 2021)

Role of the Anterior Cingulate Cortex in Translational Pain Research - Xiao Xiao; Ming Ding; Yu-Qiu Zhang (Neuroscience Bulletin, 2021)

Integrating unconditional and conditional QTLs to dissect the genetic basis of stem mechanical strength in Brassica napus L - Kunjiang Yu; Wei Zhang; Yue Guo; Ming Zheng; Feng Chen; Chengming Sun; Maolong Hu; Entang Tian; Xiaodong Wang; Jiefu Zhang (Euphytica, 2021)

Patterns of rainfall-threshold for debris-flow occurrence in the Wenchuan seismic region, Southwest China - Ming Chang; Xiangyang Dou; Tristram C. Hales; Bin Yu (Bulletin of Engineering Geology and the Environment, 2021)

Pseudomonas laoshanensis sp. nov., isolated from peanut field soil - Ming-Qing Wang; Chu-Shu Zhang; Li-Na Yu; Wei-Qiang Yang; Kun Jiao; Kui-Jie Gong; Xiao-Yuan Chi; Jie Bi; Yu Song; Qing-Li Yang; Jian-Cheng Zhang; Gui-Wen Yang; et al. (Archives of Microbiology, 2021)

Cloning and functional characterization of auxin receptor TIR1 in Gossypium hirsutum - Yu Wu; Hainan Ming; Jing Xu; Jie Bing; Qing Chen; Qing Wang; Hongjie Li; Genfa Zhang (Acta Physiologiae Plantarum, 2021)

Multi-Model Approach on Growth Estimation and Association With Life History Trait for Elasmobranchs - Kwang-Ming Liu; Chiao-Bin Wu; Shoou-Jeng Joung; Wen-Pei Tsai; Kuan-Yu Su (Frontiers in Marine Science, 2021)
Age and growth information is essential for stock assessment of fish, and growth model selection may influence the accuracy of stock assessment and subsequent fishery management decision making. Previous descriptions of the age and growth of elasmobranchs relied mainly on the von Bertalanffy growth model (VBGM). However, it has been noted that sharks, skates and rays exhibit significant variety in size, shape, and life history traits. Given this variation, the VBGM may not necessarily provide the best fit for all elasmobranchs. This study attempts to improve the growth estimates by using multi-model approach to test four growth models—the VBGM, the two-parameter VBGM, the Robertson (Logistic) and the Gompertz models to fit observed or simulated length-at-age data for 38 species (44 cases) of elasmobranchs. The best-fit growth model was selected based on the bias corrected Akaike’s Information Criterion (AIC c ), the AIC c difference, the AIC c weight, the Bayesian Information Criterion (BIC), and the Leave-one-out cross-validation (LOOCV). The VBGM and two-parameter VBGM provide the best fit for species with slow growth and extended longevity (L ∞ > 100 cm TL, 0.02 < k < 0.25 yr –1 ), such as pelagic sharks. For fast-growing small sharks (L ∞ < 100 cm TL, k r or k g > 0.2 yr –1 ) in deep waters and for small-sized demersal skates/rays, the Robertson and the Gompertz models provide the best fit. The best-fit growth models for small sharks in shallow waters are the two-parameter VBGM and the Robertson model. Although it was found that the best-fit growth models for elasmobranchs were associated with their life history trait, exceptions were also noted. Therefore, a multi-model approach incorporating with the best-fit model selected for each group in this study was recommended in growth estimation for elasmobranchs.

Early Neoproterozoic granitic gneisses in the Amdo micro-continent, Tibet: petrogenesis and geodynamic implications - Yun-Peng Yu; Chao-Ming Xie; Yong-Sheng Dong; Yu-Chao Dong; Bin Wang; Meng-Long Duan; Yu-Hang Song (International Geology Review, 2021)

Down-regulation of MANNANASE7 gene in Brassica napus L. enhances silique dehiscence-resistance - Yu-Long Li; Yan-Kun Yu; Ke-Ming Zhu; Li-Na Ding; Zheng Wang; Yan-Hua Yang; Jun Cao; Li-Zhang Xu; Yao-Ming Li; Xiao-Li Tan (Plant Cell Reports, 2021)

Diversity-oriented synthesis and antifungal activities of novel pimprinine derivative bearing a 1,3,4-oxadiazole-5-thioether moiety - Zi-Long Song; Yun Zhu; Jing-Rui Liu; Shu-Ke Guo; Yu-Cheng Gu; Xinya Han; Hong-Qiang Dong; Qi Sun; Wei-Hua Zhang; Ming-Zhi Zhang (Molecular Diversity, 2021)

Coseismic landslides induced by the 2018 Mw 6.6 Iburi, Japan, Earthquake: spatial distribution, key factors weight, and susceptibility regionalization - Ming Chang; Yu Zhou; Chao Zhou; Tristram C. Hales (Landslides, 2021)

Preliminary report on the improved resistance towards Pseudomonas syringae pv. actinidiae of cultivated kiwifruit (Actinidia chinensis) when grafted onto wild Actinidia guilinensis rootstock in vitro - Fa-ming Wang; Jie-wei Li; Kai-yu Ye; Hong-juan Gong; Ping-ping Liu; Qiao-sheng Jiang; Bei-bei Qi; Quan-hui Mo (Journal of Plant Pathology, 2021)

Effects of chemical solutions on the hydromechanical behavior of a laterite/bentonite mixture used as an engineered barrier - Yong He; Ming-ming Wang; Dong-yu Wu; Ke-neng Zhang; Yong-gui Chen; Wei-min Ye (Bulletin of Engineering Geology and the Environment, 2021)

Use of biochar as feed supplements for animal farming - Ka Yan Man; Ka Lai Chow; Yu Bon Man; Wing Yin Mo; Ming Hung Wong (Critical Reviews in Environmental Science and Technology, 2021)

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Dynamic Brain Responses Modulated by Precise Timing Prediction in an Opposing Process - Minpeng Xu; Jiayuan Meng; Haiqing Yu; Tzyy-Ping Jung; Dong Ming (Neuroscience Bulletin, 2021)

Construction of high-density genetic maps defined sex determination region of the Y chromosome in spinach - Li’ang Yu; Xiaokai Ma; Ban Deng; Jingjing Yue; Ray Ming (Molecular Genetics and Genomics, 2021)

Critical roles of macrophages in pressure overload-induced cardiac remodeling - Dan Yang; Han-Qing Liu; Fang-Yuan Liu; Nan Tang; Zhen Guo; Shu-Qing Ma; Peng An; Ming-Yu Wang; Hai-Ming Wu; Zheng Yang; Di Fan; Qi-Zhu Tang (Journal of Molecular Medicine, 2021)

Interannual variability of larval fish assemblages associated with water masses in winter in the Taiwan Strait during 2007–2013 - Yu-Kai Chen; Chia-Yi Pan; Yi-Chen Wang; Hsiu-Ju Tseng; Bo-Kun Su; Ming-An Lee (Fisheries Science, 2021)
In this study, the interannual variations of ichthyoplankton assemblages in the Taiwan Strait (TS) during the winters of 2007–2013 were determined. The cold China Coastal Current (CCC) and Mixed China Coastal Water (MCCW) intruded into the TS and impinged with the warm Kuroshio Branch Current (KBC) with annual variations. Consequently, the ichthyoplankton community in the TS was mainly structured into two assemblages characterized by differing environmental conditions. The composition of the warm KBC assemblage was relatively stable and was characterized by Diaphus B and Bregmaceros spp. By contrast, the cold MCCW assemblage demonstrated considerable variations over the years, with demersal Gobiidae and Scorpaenidae families considered the most representative. In addition, Benthosema pterotum and Trichiurus spp. were common in both KBC and MCCW assemblages. The distribution of the KBC assemblage demonstrated sharp boundaries in the frontal zones, whereas changes in the assemblage structure between the frontal zones were gradual for the MCCW assemblage, particularly when demersal taxa were dominant. Sea surface temperature and salinity were most strongly associated with variability in the assemblage structure during the study period. Thus, this paper provides a better understanding of long-term larval fish dynamics during winter in the TS.

Nutrients Have a Different Impact on the Salt Tolerance of Two Coexisting Suaeda Species in the Yellow River Delta - Qi-Hui Zhang; Kulihong Sairebieli; Ming-Ming Zhao; Xiao-Han Sun; Wei Wang; Xiao-Na Yu; Ning Du; Wei-Hua Guo (Wetlands, 2020)

Natural products development under epigenetic modulation in fungi - Chi-Ying Li; Yu-Ming Chung; Yang-Chang Wu; Attila Hunyadi; Clay C. C. Wang; Fang-Rong Chang (Phytochemistry Reviews, 2020)

A review of the Chinese monotypic genus Melliodendron (Styracaceae), with a new synonym of M. xylocarpum - Xue-Hui Wu; Rui Zhang; Timothy M. A. Utteridge; Yu-Lin Liu; Guang-Yao Yang; Ming Tang (Kew Bulletin, 2020)

Correction to: 4-Phenylbutyric acid protects against vasculitic peripheral neuropathy induced by ischaemia–reperfusion through attenuating endoplasmic reticulum stress - Cay‑Huyen Chen; Ping‑Chen Shih; Han‑Yu Lin; Po‑Kai Wang; Po‑Ting Pan; Ching‑Wei Chuang; Ming‑Chang Kao (Inflammopharmacology, 2020)

Enrichment of cadmium in rice (Oryza sativa L.) grown under different exogenous pollution sources - Yi-Min Zhou; Si-Si Long; Bing-Yu Li; Ya-Yuan Huang; Yong-Jie Li; Jia-Yan Yu; Hui-Hui Du; Sardar Khan; Ming Lei (Environmental Science and Pollution Research, 2020)

HuR Promotes Ovarian Cancer Cell Proliferation by Regulating TIMM44 mRNA Stability - Xiaohui Yu; Yujiao Li; Yumei Ding; Hong Zhang; Ning Ding; Ming Lu (Cell Biochemistry and Biophysics, 2020)

The discovery of potential phosphopantetheinyl transferase Ppt2 inhibitors against drug-resistant Candida albicans - Ling-Ning Meng; Jin-Yan Liu; Yu-Ting Wang; Shuai-Shuai Ni; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2020)

Gut dysbiosis-influence on amygdala-based functional activity in patients with end stage renal disease: a preliminary study - Li Juan Zheng; Li Lin; Jianhui Zhong; Zhihong Zhang; Yu Bing Ye; Xin Yuan Zhang; Yun Fei Wang; Han Zhang; Ya Liu; Guang Ming Lu; Dehua Gong; Long Jiang Zhang (Brain Imaging and Behavior, 2020)

Overexpression of a multifunctional β-glucosidase gene from thermophilic archaeon Sulfolobus solfataricus in transgenic tobacco could facilitate glucose release and its use as a reporter - Chih-Hao Huang; Tzu-Ling Huang; Yu-Chang Liu; Ting-Chieh Chen; Shih-Ming Lin; Shyh-Yu Shaw; Ching-Chun Chang (Transgenic Research, 2020)

3D inversion of audio-magnetotelluric data for mineral exploration: A case study of Layikeleke buried porphyry copper deposit, Xinjiang, China - Fu Guang-Ming; Yan Jia-Yong; Chen Hui; Meng Gui-Xiang; Yu Hui; Luo Fan; Luo Lei; Tao Xin (Applied Geophysics, 2020)

New α -ditetralonyl glucoside from the green walnut husk of Juglans mandshurica - An-Dong Wang; Xin-Yu Xie; Wei-Ming Zeng; Jian-Yu Liu; Yong-Nan Xu (Natural Product Research, 2020)

Pleiotropic regulation of daptomycin synthesis by DptR1, a LuxR family transcriptional regulator - Guanghai Yu; Ming Hui; Ruifang Li; Shuaibing Zhang (World Journal of Microbiology and Biotechnology, 2020)

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions - Xiuxiu Li; Zhuo Chen; Guomin Zhang; Hongwei Lu; Peng Qin; Ming Qi; Ying Yu; Bingke Jiao; Xianfeng Zhao; Qiang Gao; Hao Wang; Yunyu Wu; et al. (Science China Life Sciences, 2020)

Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex - Fen Zheng; Chao Ye; Guo-Wei Wan; Bing Zhou; Ying Tong; Jian-Zhen Lei; Qi Chen; Yue-Hua Li; Yu-Ming Kang; Guo-Qing Zhu (Pflügers Archiv - European Journal of Physiology, 2020)

Whole-Brain Map of Long-Range Monosynaptic Inputs to Different Cell Types in the Amygdala of the Mouse - Jia-Yu Fu; Xiao-Dan Yu; Yi Zhu; Shi-Ze Xie; Meng-Yu Tang; Bin Yu; Xiao-Ming Li (Neuroscience Bulletin, 2020)
The amygdala, which is involved in various behaviors and emotions, is reported to connect with the whole brain. However, the long-range inputs of distinct cell types have not yet been defined. Here, we used a retrograde trans-synaptic rabies virus to generate a whole-brain map of inputs to the main cell types in the mouse amygdala. We identified 37 individual regions that projected to neurons expressing vesicular glutamate transporter 2, 78 regions to parvalbumin-expressing neurons, 104 regions to neurons expressing protein kinase C-δ, and 89 regions to somatostatin-expressing neurons. The amygdala received massive projections from the isocortex and striatum. Several nuclei, such as the caudate-putamen and the CA1 field of the hippocampus, exhibited input preferences to different cell types in the amygdala. Notably, we identified several novel input areas, including the substantia innominata and zona incerta. These findings provide anatomical evidence to help understand the precise connections and diverse functions of the amygdala.

Synthesis and molecular docking studies of novel pyrimidine derivatives as potential antibacterial agents - Xue-Qian Bai; Chun-Shi Li; Ming-Yue Cui; Ze-Wen Song; Xing-Yu Zhou; Chao Zhang; Yang Zhao; Tian-Yi Zhang; Tie-Yan Jiang (Molecular Diversity, 2020)

Two new species of Hortiboletus (Boletaceae, Boletales) from China - Hui-Jing Xie; Wen-Fei Lin; Shuai Jiang; Rou Xue; Lu-Ling Wu; Yu-Zhuo Zhang; Zhi-Qun Liang; Nian-Kai Zeng; Ming-Sheng Su (Mycological Progress, 2020)

Saturated permeability behavior of biochar-amended clay - Wen-Jing Sun; Ming-Yu Li; Wen-Jie Zhang; Yun-Zhi Tan (Journal of Soils and Sediments, 2020)

Body weight, CYP2C19, and P2Y12 receptor polymorphisms relate to clopidogrel resistance in a cohort of Chinese ischemic stroke patients with aspirin intolerance - Zhiqiang Li; Wanqing Dong; Daorong Yang; Linhai Sun; Xianjun He; Huanhuan Hu; Jianping Zhang; Chunyu Wang; Yulin Li; Ming Zhao; Yu Kong; Yan Wang (European Journal of Clinical Pharmacology, 2020)

Optimizing the MIC breakpoints of amoxicillin and tetracycline for antibiotic selection in the rescue therapy of H. pylori with bismuth quadruple regimen - Ming-Tsung Hsieh; Wei-Lun Chang; Chung-Tai Wu; Hsiao-Bai Yang; Hsin-Yu Kuo; Meng-Ying Lin; Hsiu-Chi Cheng; Yu-Chin Tsai; Bor-Shyang Sheu (European Journal of Clinical Pharmacology, 2020)

Effects of intercropping accumulator plants and applying their straw on the growth and cadmium accumulation of Brassica chinensis L. - Yi Tang; Liming Wang; Yongdong Xie; Xuena Yu; LiJin Lin; Huanxiu Li; Ming’an Liao; Zhihui Wang; Guochao Sun; Dong Liang; Hui Xia; Xun Wang; et al. (Environmental Science and Pollution Research, 2020)

Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells - Robert Szulcek; Gonzalo Sanchez-Duffhues; Nina Rol; Xiaoke Pan; Roula Tsonaka; Chris Dickhoff; Lai Ming Yung; Xue D. Manz; Kondababu Kurakula; Szymon M. Kiełbasa; Hailiang Mei; Wim Timens; et al. (Angiogenesis, 2020)
Imbalanced transforming growth factor beta (TGFβ) and bone morphogenetic protein (BMP) signaling are postulated to favor a pathological pulmonary endothelial cell (EC) phenotype in pulmonary arterial hypertension (PAH). BMP9 is shown to reinstate BMP receptor type-II (BMPR2) levels and thereby mitigate hemodynamic and vascular abnormalities in several animal models of pulmonary hypertension (PH). Yet, responses of the pulmonary endothelium of PAH patients to BMP9 are unknown. Therefore, we treated primary PAH patient-derived and healthy pulmonary ECs with BMP9 and observed that stimulation induces transient transcriptional signaling associated with the process of endothelial-to-mesenchymal transition (EndMT). However, solely PAH pulmonary ECs showed signs of a mesenchymal trans-differentiation characterized by a loss of VE-cadherin, induction of transgelin (SM22α), and reorganization of the cytoskeleton. In the PAH cells, a prolonged EndMT signaling was found accompanied by sustained elevation of pro-inflammatory, pro-hypoxic, and pro-apoptotic signaling. Herein we identified interleukin-6 (IL6)-dependent signaling to be the central mediator required for the BMP9-induced phenotypic change in PAH pulmonary ECs. Furthermore, we were able to target the BMP9-induced EndMT process by an IL6 capturing antibody that normalized autocrine IL6 levels, prevented mesenchymal transformation, and maintained a functional EC phenotype in PAH pulmonary ECs. In conclusion, our results show that the BMP9-induced aberrant EndMT in PAH pulmonary ECs is dependent on exacerbated pro-inflammatory signaling mediated through IL6.

A review of the genus Strophidon ( Anguilliformes: Muraenidae ), with description of a new species - Wen‐Chien Huang; Anil Mohapatra; Pham The Thu; Hong‐Ming Chen; Te‐Yu Liao (Journal of Fish Biology, 2020)
Strophidon McClelland is a muraenid genus with characteristic appearance of a very elongated body, a large mouth cleft and anteriorly placed eyes. The nomenclature and taxonomic history of species within Strophidon are contentious and its members are easily misidentified. In the present study, species of the genus Strophidon are revised based on morphological and molecular data, and five species are considered valid, including S. dawydoffi Prokofiev, S. dorsalis (Seale), S. sathete (Hamilton), S. ui Tanaka and a new species, S. tetraporus . Strophidon tetraporus sp. nov. is described based on 15 specimens from Indonesia, the Philippines, Taiwan and Vietnam with the unique characteristic of the constant presence of the fourth infraorbital pore among species of Strophidon . The intraspecific variation of vertebral formula within S. dorsalis is discussed based on molecular data. Muraena macrurus Bleeker and Thyrsoidea longissima Kaup are synonyms of S. sathete that can be distinguished from the most similar congener S. ui by a longer tail, smaller eyes and more inner maxillary and inner dentary teeth. A key to identify species of Strophidon is provided. The distribution and maximum size of each species are also re‐evaluated.