Observation and research of deep underground multi-physical fields—Huainan −848 m deep experiment - Yun Wang; Yaxin Yang; Heping Sun; Chengliang Xie; Qisheng Zhang; Xiaoming Cui; Chang Chen; Yongsheng He; Qiangqiang Miao; Chaomin Mu; Lianghui Guo; Jiwen Teng (Science China Earth Sciences, 2023)
Compared with the surface, the deep environment has the advantages of allowing “super-quiet and ultra-clean”-geophysical field observation with low vibration noise and little electromagnetic interference, which are conducive to therealization of long-term and high-precision observation of multi-physical fields, thus enabling the solution of a series of geoscience problems. In the Panyidong Coal Mine, where there are extensive underground tunnels at the depth of 848 m belowsea level, we carried out the first deep-underground geophysical observations, including radioactivity, gravity, magnetic, magne-totelluric, background vibration and six-component seismic observations. We concluded from these measurements that (1) the background of deep subsurface gravity noise in the long-period frequency band less than 2 Hz is nearly two orders ofmagnitude weaker than that in the surface observation environment; (2) the underground electric field is obviously weaker thanthe surface electric field, and the relatively high frequency of the underground field, greater than 1 Hz, is more than two orders of magnitude weaker than that of the surface electric field; the east-west magnetic field underground is approximately the same asthat at the surface; the relatively high-frequency north-south magnetic field underground, below 10 Hz, is at least one order ofmagnitude lower than that at the surface, showing that the underground has a clean electromagnetic environment; (3) in additionto the high-frequency and single-frequency noises introduced by underground human activities, the deep underground spacehas a sig-nificantly lower background vibration noise than the surface, which is very beneficial to the detection of weakearthquake and gravity signals; and (4) the underground roadway support system built with ferromagnetic material interferesthe geomagnetic field. We also found that for deep observation in the “ultra-quiet and ultra-clean” environment, the existinggeophysical equipment and observation technology have problems of poor adaptability and insufficient precision as well asdata cleaning problems, such as the effective separation of the signal and noise of deep observation data. It is also urgent tointerpret and comprehensively utilize these high-precision multi-physics observation data.

Longitudinal expression profiles of flavonoid synthesis-related genes and their correlations with contents of flavonoids including anthocyanins in purplish-green aerial stems of Panax notoginseng - Hongling Zhang; Guiqiong Li; Min Jiang; Changling Zhao; Pengyu Zhao; Chen Wang; Guosong Wen; Feng Zhou; Wenhua Dongchen; Shaozhong Xu; Ting Mu; Fanlai Meng; et al. (Acta Physiologiae Plantarum, 2023)

Degradation of petroleum pollutants in oil-based drilling cuttings using an Fe2+-based Fenton-like advanced oxidation processes - Xinglong Chen; Shiqi Mu; Yuanfeng Luo (Environmental Science and Pollution Research, 2022)

Comparative Transcriptomics Reveals the microRNA-Mediated Immune Response of Large Yellow Croaker (Larimichthys crocea) to Pseudomonas plecoglossicida Infection - Huazhi Chen; Yameng Zhang; Guangming Shao; You Chen; Yibo Shen; Yinnan Mu; Xinhua Chen (Fishes, 2022)
Visceral white nodules disease (VWND), caused by Pseudomonas plecoglossicida, is a common disease among cage-farmed large yellow croaker (Larimichthys crocea) in China. However, comprehensive investigations of the molecular defensive mechanisms used by L. crocea in response to P. plecoglossicida infection remain relatively rare. Here, we constructed transcriptomes of the L. crocea spleen at 12 h and 24 h after P. plecoglossicida challenge. We identified 518 novel miRNAs and 823 known miRNAs in the spleen of L. crocea. Between the challenge and control groups, 32 differentially expressed miRNAs (DEmiRNAs), predicted to target 356 genes, and 1152 differentially expressed mRNAs (DEmRNAs) were identified at 12 h post-infection, while 33 DEmiRNAs, predicted to target 278 genes, and 1067 DEmRNAs were identified at 24 h post-infection. Gene ontology (GO) analysis showed that 146 and 126 GO terms were significantly enriched in the target genes at 12 h and 24 h, respectively. Twenty-eight and four immune-associated Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were significantly enriched in the target genes at 12 h and 24 h, respectively. Three immune-associated pathways were among those most enriched in the target genes: Toll-like receptor signaling, endocytosis, and C-type lectin receptor signaling. Network analysis identified 47 DEmRNA-DEmiRNA pairs. In particular, the immune-related genes TLR5S and PIGR were targeted by the miRNAs lcr-miR-7132c and dre-miR-183-5p, respectively. Dual-luciferase assays verified that lcr-miR-7132c downregulated TLR5S, suggesting that this miRNA may participate in regulating the immune response of L. crocea to P. plecoglossicida infection through the TLR5S-mediated signaling pathway. Our results help to clarify the miRNA-mediated immune response of L. crocea to P. plecoglossicida infection.

Co-composting of cattle manure and wheat straw covered with a semipermeable membrane: organic matter humification and bacterial community succession - Yingjin Song; Ruiyi Li; Yuxin Wang; Yu Hou; Guanyi Chen; Beibei Yan; Zhanjun Cheng; Lan Mu (Environmental Science and Pollution Research, 2022)

Body mass index–based predictions and personalized clinical strategies for colorectal cancer in the context of PPPM - Yun-Jia Gu; Li-Ming Chen; Mu-En Gu; Hong-Xiao Xu; Jing Li; Lu-Yi Wu (EPMA Journal, 2022)
Currently colorectal cancer (CRC) is the third most prevalent cancer worldwide. Body mass index (BMI) is frequently used in CRC screening and risk assessment to quantitatively evaluate weight. However, the impact of BMI on clinical strategies for CRC has received little attention. Within the framework of the predictive, preventive, and personalized medicine (3PM/PPPM), we hypothesized that BMI stratification would affect the primary, secondary, and tertiary care options for CRC and we conducted a critical evidence-based review. BMI dynamically influences CRC outcomes, which helps avoiding adverse treatment effects. The outcome of surgical and radiation treatment is adversely affected by overweight (BMI ≥ 30) or underweight (BMI < 20). A number of interventions, such as enhanced recovery after surgery and robotic surgery, can be applied to CRC at all levels of BMI. BMI-controlling modalities such as exercise, diet control, nutritional therapy, and medications may be potentially beneficial for patients with CRC. Patients with overweight are advised to lose weight through diet, medication, and physical activity while patients suffering of underweight require more focus on nutrition. BMI assists patients with CRC in better managing their weight, which decreases the incidence of adverse prognostic events during treatment. BMI is accessible, noninvasive, and highly predictive of clinical outcomes in CRC. The cost–benefit of the PPPM paradigm in developing countries can be advanced, and the clinical benefit for patients can be improved with the promotion of BMI-based clinical strategy models for CRC.

Prediction of Groundwater Quality Using Seven Types of First-Order Univariate Grey Model in the Chishan Basin, Taiwan - Tzu-Yi Pai; Ray-Shyan Wu; Ching-Ho Chen; Huang-Mu Lo; Terng-Jou Wan; Min-Hsin Liu; Wei-Cheng Chen; Yi-Ping Lin; Chun-Tse Hsu (Water, Air, & Soil Pollution, 2022)

Environmental impact of typical zinc smelting that implements solid waste collaborative utilization in China - Wei-Ning Liu; Yao Shi; Chen-Mu Zhang; Lang-Ming Liu; Hui-Quan Li; Bin Lu; Yuan-Bo Xie; Cai-Bei Zhuang; Tian-You Sun; Wei-Ping Liu; Xue Guan; Ying-Yan Hu (The International Journal of Life Cycle Assessment, 2022)

miR-182-5p Delivered by Plasma Exosomes Promotes Sevoflurane-Induced Neuroinflammation and Cognitive Dysfunction in Aged Rats with Postoperative Cognitive Dysfunction by Targeting Brain-Derived Neurotrophic Factor and Activating NF-κB Pathway - Fu-sheng Wei; Mu-wen Rao; Yuan-lu Huang; Shi-biao Chen; Yu-qian Wu; Lei Yang (Neurotoxicity Research, 2022)

An association study on the risk, glucocorticoids effectiveness, and prognosis of systemic lupus erythematosus: insight from mitochondrial DNA copy number - Zhen Li; Qi-Qun Zong; Chun-Xia Zhai; Guang-Hui Yu; Wan-Qin Hu; Yu-Hua Wang; Lin-Lin Wang; Zi-Ye Yan; Ting-Yu Zhang; Ying Teng; Shuang Liu; Jing Cai; et al. (Immunologic Research, 2022)

Organic layer characteristics and microbial utilization of the biosulfur globules produced by haloalkaliphilic Thioalkalivibrio versutus D301 during biological desulfurization - Zhixia Liu; Maohua Yang; Tingzhen Mu; Jinlong Liu; Linxu Chen; Delu Miao; Jianmin Xing (Extremophiles, 2022)

Quantitative Assessment of the Relative Contributions of Climate and Human Factors to Net Primary Productivity in the Ili River Basin of China and Kazakhstan - Liang Liu; Jingyun Guan; Wanqiang Han; Xifeng Ju; Chen Mu; Jianghua Zheng (Chinese Geographical Science, 2022)

Predation capacity of Bradymonabacteria, a recently discovered group in the order Bradymonadales, isolated from marine sediments - Ya Gong; Xiu-Ya Ping; Chen-Hang Zeng; Shu-Xin Wang; Yi Zhou; Ming-Yi Wang; Da-Shuai Mu; Zong-Jun Du (Archives of Microbiology, 2022)

Effects of diurnal temperature fluctuations on growth performance, energy metabolism, stress response, and gut microbes of juvenile mud crab Scylla paramamosain - Jiahao Liu; Shujian Chen; Zhiming Ren; Yangfang Ye; Chunlin Wang; Changkao Mu; Qingyang Wu; Ce Shi (Frontiers in Marine Science, 2022)
A 51-day experiment was conducted to investigate the effects of diurnal temperature fluctuations (DTF) on growth performance, energy metabolism, stress response and gut microbiota of juvenile mud crab Scylla paramamosain . One control and three fluctuation groups were set up, i.e ., constant (28 ± 0°C) (CT), slight (SF) (28 ± 2°C), medium (MF) (28 ± 4°C), and large (LF) (28 ± 6°C) DTF. The survival rate tended to decrease with the intensification of DTF, the survival of rate of CT, SF, MF and LF were 80.6 ± 3.9%, 75.0 ± 6.8%, 33.3 ± 6.8%, and 30.6 ± 10.4% respectively. The crab in SF and MF had a shorter, but LF had a longer molt interval compared with the crab in the CT group. Cortisol, blood glucose (GLU), total cholesterol (T-CHO) and triglyceride (TG) levels peaked in the LF group. The exacerbation of DTF caused a dramatic increase in reactive oxygen species (ROS) levels and impacted the antioxidant capacity of juvenile crabs. The relative expression of AMP-activated protein kinase ( ampk ), heat shock protein 70 ( hsp70 ) and heat shock protein 90 ( hsp90 ) genes was significantly increased in MF group. The expression of Ribosomal protein S6 kinase ( s6k ) and Mechanistic target of rapamycin ( tor ) genes was significantly up-regulated in the SF group ( P< 0.05) but large DTF caused a decrease in the relative expression of a large number of functional genes. DTF affected the structure and function of gut microbes. The bacterial community changed with the intensification of DTF and alpha diversity continued to rise. Five biomarkers were identified, where Rhodobacterales and Rhodobacterac were significantly more abundant in the CT group, Campylobacterales,Vibrionales and erysipelotrichale s were more abundant in the SF, MF and LF groups. In addition, SF also enhanced gut microbes interactions compared with other treatments. These results suggest that drastic environmental DTF reduced the growth and survival of young mud crabs, and the effect was mediated by energy metabolism, antioxidant pathways and gut microbes.

Benthic Sargassum composition and community characteristics in the intertidal zone of Hainan Island, China - Xiaoxiao Zou; Tian Meng; Dandan Yao; Zuo Chen; Jun Zhu; Dan Mu; Shixiang Bao (Marine Biology Research, 2022)

Hepatocyte steatosis inhibits hepatitis B virus secretion via induction of endoplasmic reticulum stress - Qichuang Liu; Maoyuan Mu; Huan Chen; Guoyuan Zhang; Yanqing Yang; Jun Chu; Ying Li; Fangwan Yang; Shide Lin (Molecular and Cellular Biochemistry, 2022)

Deoxynivalenol induces caspase-3/GSDME-dependent pyroptosis and inflammation in mouse liver and HepaRG cells - Xiaoxiao Mao; Jie Li; Xin Xie; Shuang Chen; Qiang Huang; Peiqiang Mu; Jun Jiang; Yiqun Deng (Archives of Toxicology, 2022)

Two new alkaloids from Tibetan medicine of Hypecoum leptocarpum - Bo Sun; Israa Assani; Chun-Gu Wang; Mu-Xuan Wang; Ling-Fei Liu; Yan Li; Ge Yan; Yun-Ruo Yang; Zhi Chen; Zhi-Xin Liao (Natural Product Research, 2022)

Effects of tillage and cropping sequences on crop production and environmental benefits in the North China Plain - Wen-Xuan Liu; Wen-Sheng Liu; Mu-Yu Yang; Yu-Xin Wei; Zhe Chen; Ahmad Latif Virk; Rattan Lal; Xin Zhao; Hai-Lin Zhang (Environmental Science and Pollution Research, 2022)

Sensor Partitioning Placements via Random Walk and Water Quality and Leakage Detection Models within Water Distribution Systems - Tianwei Mu; Manhong Huang; Shi Tang; Rui Zhang; Gang Chen; Baiyi Jiang (Water Resources Management, 2022)

Fine mapping of powdery mildew and stripe rust resistance genes Pm5V/Yr5V transferred from Dasypyrum villosum into wheat without yield penalty - Ruiqi Zhang; Chuntian Lu; Xiangru Meng; Yali Fan; Jie Du; Runran Liu; Yigao Feng; Liping Xing; Petr Cápal; Kateřina Holušová; Jaroslav Doležel; Yiwei Wang; et al. (Theoretical and Applied Genetics, 2022)

Distribution patterns of the earthworm community in relation to soil properties and metals in agro-ecosystems in Hebei Province, North China - Yue Yin; Dianwu Wang; Miaomiao Chen; Xiaoquan Mu; Yang Yang; Bo Li; Kun Wang (Community Ecology, 2022)

Biophysical Reviews special issue call: quantitative methods to decipher cellular heterogeneity — from single-cell to spatial omic methods - Joshua W. K. Ho; Xi Chen; Mu He; Yuanhua Huang; Jessica C. Mar; David J. H. Shih; Angela R. Wu (Biophysical Reviews, 2022)

Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy - Yawei Bian; Chonglin Shi; Shan Song; Lin Mu; Ming Wu; Duojun Qiu; Jiajia Dong; Wei Zhang; Chen Yuan; Dongyun Wang; Zihui Zhou; Xuan Dong; et al. (Cell and Tissue Research, 2022)

Assessing the effectiveness and function of the water resources tax policy pilot in China - Rulin Ouyang; Enlin Mu; Yibin Yu; Ying Chen; Jiangbo Hu; Haoran Tong; Zhe Cheng (Environment, Development and Sustainability, 2022)

Late Mesozoic rifting and its deep dynamic mechanisms in the central Sulu orogenic belt: Records from Lingshan Island - Tengfei Zhou; Yaoqi Zhou; Nina Søager; Paul Martin Holm; Zhenkai Zhang; Jun Wang; Zhao Liang; Hongyu Mu; Yanjun Cheng; Feifei Liu; Miao Wang; Yue Zhang; et al. (Science China Earth Sciences, 2022)

Xinfangfangia pollutisoli sp. nov., Isolated from Clopyralid-Contaminated Soil - Yang Mu; Jia-Yi Peng; Hui-Ping Wang; Yue Song; Hong-Mei Wang; Qing Chen; Kai Chen (Current Microbiology, 2022)

A Nonlinear Representation of Model Uncertainty in a Convective-Scale Ensemble Prediction System - Zhizhen Xu; Jing Chen; Mu Mu; Guokun Dai; Yanan Ma (Advances in Atmospheric Sciences, 2022)

Synthetic lethality in personalized cancer therapy - Ying Pang; Meng Cheng; Mu Chen; Kaijun Zhao; Yuanyuan Yin; Min Liu; Jing Zhang; Chunlong Zhong (Genome Instability & Disease, 2022)

Multiple low salinity stress modes provided novel insight into the metabolic response of Scylla paramamosain adapting to inland saline-alkaline water - Mingming Niu; Gao Gao; Kangxiang Qin; Yuhao Chen; Huan Wang; Xing Li; Guoling Liang; Chunlin Wang; Changkao Mu; Qiong Su (Frontiers in Marine Science, 2022)
Scylla paramamosain is a high-quality cultivar for saline-alkaline water aquaculture as a euryhaline crustacean species. However, salinity impacts the respiratory metabolism, growth, and survival of marine crustaceans. The metabolic response of crabs adapting to multiple low salinity environments has not been thoroughly studied yet, especially in inland saline-alkaline water. In this study, we analyzed metabolites in the gill and hemolymph of crabs cultured in three different low salinity environments. The results showed that membrane composition (lipids and lipid molecules) and free amino acids played an essential role in the osmoregulation of crabs, and the energy consumption accompanied as well. Meanwhile, S. paramamosain relied on ion transport and energy metabolism under acute/short-term low salinity conditions for osmoregulation. In contrast, amino acids and energy metabolism occupied a leading position in long-term low salinity. Furthermore, taurine and hypotaurine play a vital role in crabs adapting to inland saline-alkaline water. This is the first study to identify the crucial metabolites and key pathways as biomarkers to differentiate the metabolic mechanisms of S. paramamosain under multiple low salinity stress modes based on GC-MS technology, which provided novel insight into the metabolic response of S. paramamosain adapting to inland low salinity saline-alkaline water, and provided theoretical guidance for the aquaculture of S. paramamosain in the inland saline-alkaline water.

Transcriptomic analysis of adaptive mechanisms in response to inland saline-alkaline water in the mud crab, Scylla paramamosain - Guoling Liang; Kangxiang Qin; Yuhao Chen; Mingming Niu; Huan Wang; Chunlin Wang; Changkao Mu; Lizhi Chen; Fangfang Wang; Qiong Su; Ritong Zhu (Frontiers in Marine Science, 2022)
Scylla paramamosain is an important marine aquaculture crustacean on the southeastern coast of China. Given the difficulties of overcrowded coastal aquaculture space and insufficient production, inland saline-alkaline water culture has the potential to alleviate this bottleneck. This study separated 600 crabs into four groups: normal salinity (12-18 ppt, NS), coastal low salinity (3-5 ppt, CS), inland low salinity saline-alkaline (1.5 ppt, IS), and acute low salinity (23 ppt down to 3 ppt, AS), followed by a transcriptomic analysis of the gills. CS-vs-NS, IS-vs-NS, and AS-vs-NS obtained 1154, 1012, and 707 DEGs, respectively. GO analysis showed that the DEGs of the three comparison groups were mainly involved in cellular process, metabolic process, biological regulation, organelle, membrane, extracellular region, binding, and catalytic activity. The findings demonstrate that a significant number of genes are engaged in controlling metabolic processes in the osmoregulation process, and that cell membrane catalysis and different enzymes play a vital part in the environmental adaption process. KEGG enrichment analysis revealed that IS possesses a considerable number of signaling pathways that play important roles in osmoregulation when compared to NS. The cAMP signaling pathway increased the expression of CaM and Na + /K + -ATPase. These findings show that cations like Ca 2+ , Na + , and K + are critical for S. paramamosain to adapt to inland low salinity saline-alkaline water, and that the cAMP signaling pathway regulates their levels. This research provides a theoretical foundation for improving the saline-alkaline aquaculture technology of S. paramamosain .

Quick mapping and characterization of a co-located kernel length and thousand-kernel weight-related QTL in wheat - Xiangru Qu; Cong Li; Hang Liu; Jiajun Liu; Wei Luo; Qiang Xu; Huaping Tang; Yang Mu; Mei Deng; Zhien Pu; Jun Ma; Qiantao Jiang; et al. (Theoretical and Applied Genetics, 2022)

A 215-bp indel at intron I of BoFLC2 affects flowering time in Brassica oleracea var. capitata during vernalization - Qinfei Li; Ao Peng; Jiaqin Yang; Sidi Zheng; Zhangping Li; Yinhui Mu; Lei Chen; Jun Si; Xuesong Ren; Hongyuan Song (Theoretical and Applied Genetics, 2022)

GmUGT73F4 plays important roles in enhancing seed vitality and tolerance to abiotic stresses in transgenic Arabidopsis - Huimin Hu; Peipei Qian; Mengyuan Ye; Kebin Mu; Shuang Wang; Ming Chen; Hao Ma (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Association of cognitive impairment and reduced cortical thickness in prefrontal cortex and anterior cingulate cortex with treatment-resistant depression - Mu-Hong Chen; Wan-Chen Chang; Pei-Chi Tu; Wei-Chen Lin; Cheng-Ta Li; Wen-Sheng Huang; Ya-Mei Bai; Shih-Jen Tsai; Tung-Ping Su (Brain Imaging and Behavior, 2022)

Expression Characteristics and Putative Functions of KIF3A/KIF3B During Spermiogenesis of Phascolosoma esculenta - Chen Du; Danli Mu; Xinming Gao; Shengyu Luo; Jianping Wang; Shan Jin; Junquan Zhu (Journal of Ocean University of China, 2022)

Occupancy Grid-Based AUV SLAM Method with Forward-Looking Sonar - Xiaokai Mu; Guan Yue; Nan Zhou; Congcong Chen (Journal of Marine Science and Engineering, 2022)
Simultaneous localization and mapping (SLAM) is an active localization method for Autonomous Underwater Vehicle (AUV), and it can mainly be used in unknown and complex areas such as coastal water, harbors, and wharfs. This paper presents a practical occupancy grid-based method based on forward-looking sonar for AUV. The algorithm uses an extended Kalman filter (EKF) to estimate the AUV motion states. First, the SLAM method fuses the data coming from the navigation sensors to predict the motion states. Subsequently, a novel particle swarm optimization genetic algorithm (PSO-GA) scan matching method is employed for matching the sonar scan data and grid map, and the matching pose would be used to correct the prediction states. Lastly, the estimated motion states and sonar scan data would be used to update the grid map. The experimental results based on the field data have validated that the proposed SLAM algorithm is adaptable to underwater conditions, and accurate enough to use for ocean engineering practical applications.

Studies on the Physiological Mechanism of Brassinolide to Improve the Resistance of Rice Seedlings to NaCl Stress - Dewei Mu; Naijie Feng; Dianfeng Zheng; Hang Zhou; Ling Liu; Guanjie Chen (Water, Air, & Soil Pollution, 2022)

Risk Analysis of Dynamic Water Level Setting of Reservoir in Flood Season Based on Multi-index - Zhenyu Mu; Xueshan Ai; Jie Ding; Kui Huang; Senlin Chen; Jiajun Guo; Zuo Dong (Water Resources Management, 2022)

Discovery of the non‐cosmopolitan lineages in Candidatus Thermoprofundales - Yi‐Fan Liu; Liu Yang; Zhong‐Lin Liu; Jing Chen; Bo Fang; Lei Zhou; Jin‐Feng Liu; Shi‐Zhong Yang; Ji‐Dong Gu; Bo‐Zhong Mu (Environmental Microbiology, 2022)
Summary The recently proposed order Candidatus Thermoprofundales, currently containing only one family‐level lineage Marine Benthic Group‐D (MBG‐D), is distributed in global subsurface ecosystems and ecologically important, but its diversity, evolution and metabolism remain largely unknown. Here we described two novel family‐level specialized lineages in Ca . Thermoprofundales, JdFR‐43 and HyVt, which are restricted to specific biotopes (primarily in marine hydrothermal vents and occasionally in oil reservoirs and hot springs) in contrast to the cosmopolitan lineage MBG‐D. The comparative genomics revealed that the specialized lineages have streamlined genomes, higher GC contents, enriched genes associated with nucleotide biosynthesis, ribosome biogenesis and DNA repair and additional thermostable aminopeptidases, enabling them to adapt to high‐temperature habitats such as marine hydrothermal vents, deep subsurface oil reservoirs and hot springs. On the contrary, the unique metabolic traits of the cosmopolitan MBG‐D, motility, glycolysis, butanoate metabolism, secondary metabolites production and additional genes for specific peptides and carbohydrates degradation potentially enhance its response to environmental change. Substrate preference is found for most MAGs across all lineages with the ability to utilize both polysaccharides (chitin and starch) and proteinaceous substances, whereas JdFR‐43 members from oil reservoirs can only utilize proteins. These results expand the diversity of C a . Thermoprofundales significantly and further improve our understandings of the adaptations of C a . Thermoprofundales to various environments.

Molecular cloning, characterization and expression analysis of P53 from high latitude fish Phoxinus lagowskii and its response to hypoxia - Jing Wang; Xi Chen; Xinrui Ge; Zhen Wang; Weijie Mu (Fish Physiology and Biochemistry, 2022)

Stability evaluation for steep bank slope with microseismic monitoring in Three Gorges Reservoir area - Qing-ming Xie; Kui Long; Zi-mu Li; Li-chuan Chen; Hong Liu; Hong Xu; Fei He; Dan Liang; Xue-kun Xiang; Qiang Ma (Journal of Mountain Science, 2022)

A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam - Yi-Fan Yu; Yue-Qian Li; Ru-Yue Wang; Xu Liu; Wen-Bo Cui; Xiao-Han Chen; Cheng-Mu Zhao; Feng-Ming Qi; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

Membrane lipid phosphorus reusing and antioxidant protecting played key roles in wild soybean resistance to phosphorus deficiency compared with cultivated soybean - Jing Chen; Ji Zhou; Mingxia Li; Mu Li; Yunan Hu; Tao Zhang; Lianxuan Shi (Plant and Soil, 2022)

First report of plum bark necrosis stem pitting-associated virus affecting sweet cherry in Yunnan, China - Miao Guo; Jing Zhong; Chaowen Wang; Yue Chen; Zhengsong Yang; Tingting Li; Yongbin Wu; Yongqing Mu; Ming Ding; Jiawei He (Journal of Plant Pathology, 2022)

Metabolic Response in the Gill of Portunus trituberculatus Under Short-Term Low Salinity Stress Based on GC-MS Technique - Jiali Wang; Qi Liu; Xinni Zhang; Gao Gao; Mingming Niu; Huan Wang; Lizhi Chen; Chunlin Wang; Changkao Mu; Fangfang Wang (Frontiers in Marine Science, 2022)
Salinity is an important factor affecting the survival, growth, and metabolism of marine crustaceans. Low-salt stress will result in the death of swimming crabs. This paper investigates the metabolic response in the gills of Portunus trituberculatus under short-term low-salt stress by comparing the metabolic molecules in the four salinity treatment groups (24‰, 16‰, 12‰, and 8‰) by GC-MS technique. In this study, nine common differential metabolites such as pyruvate, malic acid, and phosphoethanolamine were found in the gill tissues of crabs. KEGG enrichment analysis revealed that six metabolic pathways, including the citric acid cycle, pyruvate metabolism, and the HIF-1 signaling system, were significantly impacted by low salt stimulation. According to the findings, salinity 12‰ is a critical node in crab adaptation to low salinity. In the process of adaptation to short-term low-salinity environment, amino acids participated in osmotic regulation, and organic acids such as pyruvate and malic acid were involved in energy metabolism to ensure their energy supply. This research further enriched the theory of osmotic regulation and metabolic mechanism of adaptation to low salt in crustaceans, with the goal of providing guidance for the improvement of culture technique in Portunus trituberculatus.

Developing a salinity tolerance indicator for tree varieties at challenging sites and urban forests based on inferences of physiological responses: an example of Ulmus pumila - Deyu Mu; Chen Ding (Trees, 2022)

Overexpression of Cpg15 Alleviates the Oxidative Stress in Neuronal Cells Via Regulating Redox Enzymes and Nrf2 Antioxidative Pathway - Yi Jiang; Jun-Jie Li; Ya-Wei Mu; Han-Yang Jiang; Zi-Xuan Wei; Zi-Yao Xiao; Jing-Jing Zhao; Xian-Hua Chen (Neurotoxicity Research, 2022)

Analysis of the microseismicity characteristics in landslide dam failure flume tests: implications for early warning and dynamics inversion - Yunpeng Yang; Guan Chen; Xingmin Meng; Shiqiang Bian; Yan Chong; Wei Shi; Wanyu Jiang; Jiacheng Jin; Chen Li; Xinliang Mu; Dongxia Yue (Landslides, 2022)

Molecular characterization and expression analysis of hypoxia-inducible factor-1α, factor-2α, and factor-3α and physiological response to hypoxia exposure in Amur minnow (Phoxinus lagowskii) - Yuting Yang; Zhongdian Dong; Xi Chen; Zhen Wang; Dawei Zhang; Liqun Liang; Weijie Mu (Aquaculture International, 2022)

A framework of analytical methods for horizontal behaviours of monopiles under V-H-M loads in sand - Linlong Mu; Wei Chen; Yiming Zhang; Xiaoxiang Chen; Wan Li (Marine Georesources & Geotechnology, 2022)

Light Spectrum Impacts on Growth, Molting, and Oxidative Stress Response of the Mud Crab Scylla paramamosain - Shujian Chen; Ce Shi; Herve Migaud; Changbin Song; Changkao Mu; Yangfang Ye; Chunlin Wang; Zhiming Ren (Frontiers in Marine Science, 2022)
An 8 weeks trial was performed to test the effects of light spectra [full-spectrum, violet (405 nm), blue (470 nm), cyan (500 nm), green (525 nm), yellow (570 nm), and red (625 nm)] on growth performance, molting, antioxidant capacity, stress response and expression of molting, and apoptosis-related genes in Scylla paramamosain . Results showed that spectrum had a significant effect on S. paramamosain physiology. Compared to blue light, crabs exposed to violet light had a significantly lower survival rate (79.5 ± 3.6% vs. 94.9 ± 3.6%), weight gain (49.2 ± 5.4 vs. 67.6 ± 6.7), molt frequency (4.2 ± 0.2 vs. 4.5 ± 0.1), and extended intermolt intervals between instar 1 and 2 stages (C1–C2) (6.3 ± 0.3 vs. 5.0 ± 0.1 days). Expression of the molt-inhibiting hormone ( mih ) gene was upregulated in crabs reared under violet light. According to the regression analysis, maximum SGR would be at 449.97 nm. Crabs exposed to blue light also had lower melatonin levels than under full-spectrum and lower cortisol levels than violet and yellow groups. Regarding oxidative stress, crabs in full-spectrum had lower H 2 O 2 and MDA contents, however, no significant difference was found in total antioxidant capacity (T-AOC), superoxide dismutase (SOD), and catalase (CAT) in hepatopancreas from crabs under different spectra. Gene expression of hsp40 , hsp70 , hsp90 were down-regulated in crabs exposed to the full-spectrum light group. Regarding apoptosis-related genes, bcl-2 gene expression in crabs under cyan and the cox IV and caspase 3 in green were upregulated, suggesting cyan light may inhibit, while green light may promote apoptosis. Taken together, these results suggest that blue or cyan light would promote growth performance, while full-spectrum light could reduce stress response in S. paramamosain .

Native herbivores indirectly facilitate the growth of invasive Spartina in a eutrophic saltmarsh - Xiao Xu; Yan Zhang; Songshuo Li; Hongyang Chen; Mu Liu; Bo Li; Ming Nie (Ecology, 2022)
Current theory (e.g., consumer‐controlled theory) predicts that nutrient enrichment typically amplifies herbivory and thereby suppresses the growth and expansion of invasive plants. Herbivores can facilitate plant regrowth in the native community by stimulating complementary growth or ameliorating habitat conditions (e.g., by increasing soil oxygen and nutrient availability), but whether they have similar positive effects on invasive plants, especially under nutrient enrichment, remains unknown. Using a field nitrogen (N)‐enrichment × crab exclusion experiment, we evaluated and compared the effects of both N enrichment and crab herbivory on the growth performance of a global invasive cordgrass, Spartina alterniflora , and a co‐occurring native plant, Phragmites australis . We found that crabs consistently suppressed P. australis by density and aboveground biomass regardless of N enrichment. In contrast, for S. alterniflora , the negative effects of crabs under ambient N were replaced by positive effects under N enrichment, with crabs stimulating complementary increases in density and aboveground biomass. The differing effects between the N treatments were driven by crab burrowing activity, which increased soil N availability, and the nutrient‐use efficiency of S. alterniflora . Our findings revealed that native herbivores can have opposing effects on native and invasive plants, which broadens our understanding of how exotic plants can achieve dominance in a changing world.

Characterization and fine mapping of a lesion mimic mutant (Lm5) with enhanced stripe rust and powdery mildew resistance in bread wheat (Triticum aestivum L.) - Cong Li; Hang Liu; Jian Wang; Qi Pan; Yue Wang; Kunyan Wu; Peiying Jia; Yang Mu; Huaping Tang; Qiang Xu; Qiantao Jiang; Yaxi Liu; et al. (Theoretical and Applied Genetics, 2022)

First report of Pseudocercospora coprosmae causing leaf spot on Scaevola taccada in China - Min Li; Zhaoyin Gao; Xiqiang Song; Qing Chen; Deqiang Gong; Junxia Mu; Meijiao Hu (Journal of Plant Pathology, 2022)

Historical Connectivity and Demography of the Ferocious Reef Crab, Eriphia ferox (Crustacea; Eriphiidae), Demonstrate That Taoyuan Algal Reef Is an Essential Population Source Along the East Taiwan Strait - Mu-Han Chen; Ya-Yi Huang; Bi-Ying Huang; Hernyi Justin Hsieh; Jen Nie Lee; Mei Lin Neo; Hironobu Fukami; Chaolun Allen Chen (Frontiers in Marine Science, 2022)
The east Taiwan Strait is largely fringed by sandy and muddy habitats. However, a massive algal reef made of crustose coralline algae has been found along the coast off Taoyuan city in northwestern Taiwan. The porous structure of Taoyuan Algal Reef harbors high abundance and diversity in marine organisms, including the ferocious reef crab, Eriphia ferox . Such a pivotal geographic location and unique ecological features make Taoyuan Algal Reef a potential stepping stone connecting biotic reefs in the east Taiwan Strait, South China Sea to the south, and even the high latitude of Japan to the north. In this study, we examined the population connectivity and historical demography of E. ferox by analyzing mitochondrial cytochrome oxidase I (COI) fragments of 317 individuals sampled from 21 localities in the northwestern Pacific. Our analyses of haplotype network and pairwise F ST comparisons revealed a lack of phylogeographical structure among E. ferox populations, implying the existence of a migration corridor connecting the South and East China Seas through the east Taiwan Strait. Multiple lines of evidence, including significant values in neutrality tests, unimodally shaped mismatch distributions, and Bayesian skyline plots elucidated the rapid population growth of E. ferox following the sea-level rise after Last Glacial Maximum (ca. 2–10 Ka). Such demographic expansion in E. ferox coincided with the time when Taoyuan Algal Reef started to build up around 7,500 years ago. Coalescent migration analyses further indicated that the large and continuous E. ferox population exclusively found in Datan Algal Reef, the heart of Taoyuan Algal Reef, was a source population exporting migrants both northward and southward to the adjacent populations. The bidirectional gene flow should be attributed to larval dispersal by ocean currents and secondary contact due to historical population expansion. Instead of serving as a stepping stone, our results support that Taoyuan Algal Reef is an essential population source for biotic reef-associated species along the east Taiwan Strait, and highlight the importance of conserving such a unique ecosystem currently threatened by anthropogenic development.

Development of Recombinant Dihydrolipoamide Dehydrogenase Subunit Vaccine against Vibrio Infection in Large Yellow Croaker - Xiaomeng Li; Yuanzhen Tan; Zheng Zhang; Yupeng Huang; Pengfei Mu; Zhengwei Cui; Xinhua Chen (Fishes, 2022)
Large yellow croaker (Larimichthys crocea), an economically important marine fish in China, has suffered from serious vibriosis, which has resulted in great economic losses for the large yellow croaker industry. Vaccination has been considered to be a safe and effective method to prevent and control vibriosis. However, due to the complex diversity and serotypes of the Vibrio genus, the progress of Vibrio vaccine development is still slow. In this study, we prepared recombinant Vibrio dihydrolipoamide dehydrogenase (rDLD) protein and investigated its potential as a candidate to be a subunit vaccine against Vibrio. The lysozyme activity and the rDLD-specific antibody level in sera of large yellow croakers immunized with rDLD were significantly higher than those in the control group, and the transcript levels of proinflammatory cytokines (IL-6, IL-8, IL-1β), MHC IIα/β, CD40, CD8α, IL-4/13A, and IL-4/13B were significantly up-regulated in the spleen and head kidney of large yellow croakers immunized with rDLD, suggesting that rDLD could induce both specific and nonspecific immune responses in this species. In addition, rDLD protein increased the survival rate of large yellow croakers against Vibrio alginolyticus and Vibrio parahaemolyticus, with the relative percent of survival (RPS) being 74.5% and 66.9%, respectively. These results will facilitate the development of a potential subunit vaccine against Vibrio in large yellow croaker aquaculture.

Identification of WRKY transcription factors responding to abiotic stresses in Brassica napus L. - Hao Chen; Yongfeng Wang; Jiong Liu; Tian Zhao; Cuiling Yang; Qunying Ding; Yanfeng Zhang; Jianxin Mu; DaoJie Wang (Planta, 2022)

Exploring the Occurrence Characteristics of Microplastics in Typical Maize Farmland Soils With Long-Term Plastic Film Mulching in Northern China - Jiajia Zhang; Guoyuan Zou; Xuexia Wang; Wencheng Ding; Li Xu; Baoyin Liu; Yunsen Mu; Xuran Zhu; Lianjie Song; Yanhua Chen (Frontiers in Marine Science, 2021)
Microplastics pollution has been threatening the global environmental security, in which agricultural activities are considered as a main source of microplastics occurrence in soils. However, little is known about the occurrence characteristics of microplastics in agricultural soils with long-term plastic film mulching. Therefore, the abundance, distribution, and composition of microplastics were investigated by analyzing 225 soil samples collected from typical maize ( Zea mays L.) planting zones with and without long-term (>20 years) plastic film mulching in northern China. Microplastics abundance in mulched soils (754 ± 477 items kg –1 ) was significantly higher than that in non-mulched soils (376 ± 149 items kg –1 ), which indicated that plastic film mulching contributed half of microplastics in soils. Moreover, microplastics abundance was significantly positively related to the length of time with film mulching applied. The percentage of microplastics <0.5 mm in mulched soils (50.9%) was significantly lower than that in non-mulched soils (62.2%). Microplastics abundance and size in mulched and non-mulched soils decreased with increased soil depth. Most microplastics were fragments of polypropylene, films of polyethylene, and fibers of polyester. The proportion of films in mulched soils was significantly higher than in non-mulched soils, whereas that of fibers was significantly higher in non-mulched soils. This study confirmed that long-term plastic film mulching increases microplastics pollution in agricultural soils, warranting further evaluation of the associated ecological risks of microplastics in soil ecosystems.

Making ERRFI1-Derived Peptides ‘Bindable’ to the Allosteric Dimerization Interface of Breast Cancer ERBB3 Kinase by Adding a Nonbonded Interaction System - Chenghong Ji; Jianmin Zhuang; Yizhou Jiang; Jiangang Mu; Longhai Lin; Yide Chen (International Journal of Peptide Research and Therapeutics, 2021)

Short-term effects of real-time individual fine particulate matter exposure on lung function: a panel study in Zhuhai, China - Zi Ye; Bin Wang; Ge Mu; Yun Zhou; Weihong Qiu; Shijie Yang; Xing Wang; Zhuang Zhang; Weihong Chen (Environmental Science and Pollution Research, 2021)

Different Changing Patterns of Three NOS–NO System Activities after Ischemia–Reperfusion in Rabbit with AMI - Jun Zhang; Chao Chen; Fengpeng Li; Guangren Gao; Jinguo Fu; Heping Niu; Kai Yu; Lei Wang; Run Guo; Yanfang Wan; Zhanfeng Ma; Qianyu Zhang; et al. (Cell Biochemistry and Biophysics, 2021)

Metabolic Changes in Scylla paramamosain During Adaptation to an Acute Decrease in Salinity - Hongzhi Yao; Xing Li; Yuhao Chen; Guoling Liang; Gao Gao; Huan Wang; Chunlin Wang; Changkao Mu (Frontiers in Marine Science, 2021)
The mud crab Scylla paramamosain is an important euryhaline mariculture species. However, acute decreases in salinity seriously impact its survival and can result in large production losses. In this study, we evaluated metabolic changes in S. paramamosain exposed to an acute salinity reduction from 23 psu to 3 psu. After the salinity decrease, hemolymph osmolality declined from 726.75 to 642.38 mOsm/kg H 2 O, which was close to the physiological equilibrium state. Activities of osmolality regulation-related enzymes in the gills, including Na + -K + -ATPase, CA, and V-ATPase all increased. Using LC-MS analysis, we identified 519 metabolites (mainly lipids). Additionally, 13 significant metabolic pathways ( P < 0.05) were identified via enrichment analysis, which were mainly related to signal pathways, lipids, and transportation. Our correlation analysis, which combined LC-MS and previous GC-MS data, yielded 28 significant metabolic pathways. Amino acids and energy metabolism accounted for most of these pathways, and lipid metabolism pathways were insignificant. Our results showed that amino acids and energy metabolism were the dominant factors involved in the adaptation of S. paramamosain to acute salinity decrease, and lipid metabolites played a supporting role.

The ER membrane protein complex subunit Emc3 controls angiogenesis via the FZD4/WNT signaling axis - Mu Yang; Shujin Li; Wenjing Liu; Xiao Li; Yunqi He; Yeming Yang; Kuanxiang Sun; Lin Zhang; Wanli Tian; Lixin Duan; Huafu Chen; Dezhong Yao; et al. (Science China Life Sciences, 2021)

Experimental study on the suffusion mechanism of gap-graded soils under an exceedance hydraulic gradient - Liang Chen; Yu Wan; Jian-Jian He; Chun-Mu Luo; Shu-Fa Yan; Xian-Feng He (Natural Hazards, 2021)

A landslide in Heifangtai, northwest of the Chinese Loess Plateau: triggered factors, movement characteristics, and failure mechanism - Jia-xu Kong; Jian-qi Zhuang; Jie-wei Zhan; Zheng-wei Bai; Yan-qiu Leng; Peng-hui Ma; Jian-bing Peng; Zuo-peng Wang; Tian-feng Gu; Jia-xing Sun; Fan-chen Zhang; Yuan-jun Xu; et al. (Landslides, 2021)

Intraperitoneal injection of genistein affects the distribution and metabolism of cholesterol in female yellow catfish Tachysurus fulvidraco - Yushi Chen; Wenbin Xu; Qingji Zhang; Yilin Zhang; Ren Mu (Fish Physiology and Biochemistry, 2021)

Exposure to butylated hydroxytoluene compromises endometrial decidualization during early pregnancy - Zhifang Sun; Rufei Gao; Xuemei Chen; Xueqing Liu; Yubin Ding; Yanqing Geng; Xinyi Mu; Taihang Liu; Fangfang Li; Yingxiong Wang; Junlin He (Environmental Science and Pollution Research, 2021)

Using iTRAQ-Based Quantitative Proteomics Analysis to Identify Differentially Expressed Proteins Related to Larval Development of Portunus trituberculatus - Xiayue Chen; Changkao Mu; Ronghua Li; Yangfang Ye; Weiwei Song; Ce Shi; Lei Liu; Huan Wang; Chunlin Wang (Journal of Ocean University of China, 2021)

Lipocalin-2-induced proliferative endoplasmic reticulum stress participates in Kawasaki disease-related pulmonary arterial abnormalities - Zhaoling Shi; Yue Yin; Chen Li; Hui Ding; Nan Mu; Yishi Wang; Shanshan Jin; Heng Ma; Manling Liu; Jie Zhou (Science China Life Sciences, 2021)

Sources of 24-h personal exposure to PM2.5-bound metals: results from a panel study in Wuhan, China - Xing Wang; Bin Wang; Lili Xiao; Xiuqing Cui; Xingzu Cen; Shijie Yang; Ge Mu; Tao Xu; Min Zhou; Weihong Chen (Environmental Science and Pollution Research, 2021)

Proton Pump Inhibitor Exposure and Acute Myocardial Infarction Risk: A Nested Cohort Study - Hsiang-Jung Tseng; Chih-Ming Cheng; Shih-Jen Tsai; Wei-Chen Lin; Ya-Mei Bai; Chia-Fen Tsai; Tung-Ping Su; Cheng-Ta Li; Tzeng-Ji Chen; Mu-Hong Chen (Cardiovascular Toxicology, 2021)

Altered dynamics of functional connectivity density associated with early and advanced stages of motor training in tennis and table tennis athletes - Qing Gao; Yue Huang; Yu Xiang; Chengbo Yang; Mu Zhang; Jingpu Guo; Hu Wang; Jiali Yu; Qian Cui; Huafu Chen (Brain Imaging and Behavior, 2021)

FucP mediates fucose to regulate T3SS in Edwardsiella piscicida and promotes intestinal colonization in Tilapia - Tingqi Ye; Jiayan Wu; Cuimin Mu; Guangchen Pan; Jiakang Chen; Xuepeng Wang (Aquaculture International, 2021)

Fibroblast Growth Factor 9 Stimulates Neuronal Length Through NF-kB Signaling in Striatal Cell Huntington’s Disease Models - Issa Olakunle Yusuf; Hsiu-Mei Chen; Pei-Hsun Cheng; Chih-Yi Chang; Shaw-Jenq Tsai; Jih-Ing Chuang; Chia-Ching Wu; Bu-Miin Huang; H. Sunny Sun; Chuan-Mu Chen; Shang-Hsun Yang (Molecular Neurobiology, 2021)

Role of Wnt signaling pathways in type 2 diabetes mellitus - Jing Chen; Chong Ning; Jingjing Mu; Dongnan Li; Yan Ma; Xianjun Meng (Molecular and Cellular Biochemistry, 2021)

Synchronized research on endothelial dysfunction and microcirculation structure in dorsal skin of rats with type 2 diabetes mellitus - Yajie Wei; Huimin Chen; Qingzhuo Chi; Ying He; Lizhong Mu; Chao Liu; Yunxia Lu (Medical & Biological Engineering & Computing, 2021)

Strategies for culturing active/dormant marine microbes - Da-Shuai Mu; Yang Ouyang; Guan-Jun Chen; Zong-Jun Du (Marine Life Science & Technology, 2021)

Preliminary calibration results of the HY-2B altimeter’s SSH at China’s Wanshan calibration site - Chuntao Chen; Jianhua Zhu; Chaofei Ma; Mingsen Lin; Longhao Yan; Xiaoqi Huang; Wanlin Zhai; Bo Mu; Yongjun Jia (Acta Oceanologica Sinica, 2021)

The role of UhpA in regulating the virulence gene expression in Edwardsiella piscicida - Tingqi Ye; Cuimin Mu; Jiakang Chen; Guangchen Pan; Xuepeng Wang (Journal of Fish Diseases, 2021)
Edwardsiella piscicida ( E. piscicida ) is an important fish pathogen. However, the mechanism of Glu6P transport regulatory protein UhpA how to affect the virulence gene expression in E. piscicida is still unclear. The results in this study showed that the metabolism‐related gene expression of cysteine synthase (orf 1134) and sulphate transporter ( ych M) in the uhp A mutant strain Δ uhpA was 0.76‐fold and 0.68‐fold lower than the ones in the wild strains ( p uhp A strain was 0.80‐fold and 0.72‐fold lower than the ones in the wild strains ( p fliC and flgN in the Δ uhpA was 1.51‐fold and 1.21‐fold higher than the ones in the wild strains ( p esrB and esrC ) and T6SS ( evpB and evpC ) in the Δ uhpA was 1.27‐fold, 1.13‐fold, 1.28‐fold and 1.23‐fold higher than the ones in the wild strains ( p uhp A gene could regulate the key virulence gene expression, and the uhp A gene was associated with the pathogenicity of E. piscicida in fish.

Correction to: A Brush–Spin–Coating Method for Fabricating In Vitro Patient-Specific Vascular Models by Coupling 3D-Printing - Qing-Zhuo Chi; Li-Zhong Mu; Ying He; Yong Luan; Yu-Chen Jing (Cardiovascular Engineering and Technology, 2021)

A Brush–Spin–Coating Method for Fabricating In Vitro Patient-Specific Vascular Models by Coupling 3D-Printing - Qing-Zhuo Chi; Li-Zhong Mu; Ying He; Yong Luan; Yu-Chen Jing (Cardiovascular Engineering and Technology, 2021)

Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71 - Ya-Ping Li; Mu-Qi Wang; Chen-Rui Liu; Hui-Ling Deng; Yuan Wu; Shuang-Suo Dang; Li-Hong Xu (Archives of Virology, 2021)

Molecular and functional identification of a β‐defensin homolog in large yellow croaker ( Larimichthys crocea ) - Kexin Li; Wanru Li; Xiaojuan Chen; Tian Luo; Yinnan Mu; Xinhua Chen (Journal of Fish Diseases, 2021)
β‐defensin (BD) is a cysteine‐rich cationic antibacterial peptide that is active against a wide range of bacteria. Here, a β‐defensin homolog ( Lc BD2) was identified in large yellow croaker ( Larimichthys crocea ). The open reading frame of Lc BD2 contains 195 nucleotides, encoding a protein of 64 amino acids that possesses a typical arrangement of six conserved cysteine residues (C 31 , C 37 , C 41 , C 53 , C 59 and C 60 ). Lc BD2 transcripts were constitutively expressed in all examined tissues and significantly increased in head kidney, spleen and gills by Vibrio alginolyticus . The synthetic Lc BD2 peptide imparted antimicrobial effects on both Gram‐negative bacteria ( V . campbellii , V . parahaemolyticus , V . alginolyticus , V . harveyi and Pseudomonas plecoglossicida ) and Gram‐positive bacteria ( Bacillus subtilis ). We also observed that after treatment with synthetic Lc BD2 peptide, numerous blisters appeared on the membrane of P . plecoglossicida , which in turn may result in cell membrane breakage and bacterial death. Moreover, the synthetic Lc BD2 peptide significantly upregulated the expression levels of TNF‐α2, IL‐1β and CXCL8_L1 in monocytes/macrophages, while downregulated expression level of IL‐10. The Lc BD2 peptide also remarkedly enhanced the phagocytosis of monocytes/macrophages. These results indicate that Lc BD2 not only protects large yellow croaker against multiple bacterial pathogens but also plays a role in activation of monocytes/macrophages.

Interest-activity symptom severity predicts response to ketamine infusion in treatment-resistant depression - Mu-Hong Chen; Wei-Chen Lin; Hui-Ju Wu; Ya-Mei Bai; Cheng-Ta Li; Shih-Jen Tsai; Chen-Jee Hong; Pei-Chi Tu; Tung-Ping Su (Psychopharmacology, 2021)

The regulation of the small-conductance calcium-activated potassium current and the mechanisms of sex dimorphism in J wave syndrome - Mu Chen; Yudong Fei; Tai-Zhong Chen; Yi-Gang Li; Peng-Sheng Chen (Pflügers Archiv - European Journal of Physiology, 2021)

Association of FMO3 rs1736557 polymorphism with clopidogrel response in Chinese patients with coronary artery disease - Kong-Xiang Zhu; Pei-Yuan Song; He-Li; Mu-Peng Li; Yin-xiao Du; Qi-lin Ma; Li-Ming Peng; Xiao-Ping Chen (European Journal of Clinical Pharmacology, 2021)

Freeze-thaw resistance of eco-material stabilized loess - Guo-yu Li; Xin Hou; Yu Zhou; Wei Ma; Yan-hu Mu; Dun Chen; Li-yun Tang (Journal of Mountain Science, 2021)

Isolation and molecular characterization of bovine herpesvirus 4 from cattle in mainland China - Jun Lin; Rui-Hong Chen; Mu-Jiao Yang; Yuan-Mao Zhu; Fei Xue (Archives of Virology, 2021)

QTL mapping and validation of bread wheat flag leaf morphology across multiple environments in different genetic backgrounds - Yang Tu; Hang Liu; Jiajun Liu; Huaping Tang; Yang Mu; Mei Deng; Qiantao Jiang; Yaxi Liu; Guoyue Chen; Jirui Wang; Pengfei Qi; Zhien Pu; et al. (Theoretical and Applied Genetics, 2021)

A plant virus mediates interspecific competition between its insect vectors in Capsicuum annuum - Yong Chen; Xue Zheng; Hui Wei; Yong-Dui Chen; Kuan-Yu Zheng; Ye Mu; Xing-Yue Zhao; Li-Hua Zhao; Yu-Lin Gao; Li-Min Zheng; Jie Zhang (Journal of Pest Science, 2021)

A novel, validated, and plant height-independent QTL for spike extension length is associated with yield-related traits in wheat - Cong Li; Huaping Tang; Wei Luo; Xuemei Zhang; Yang Mu; Mei Deng; Yaxi Liu; Qiantao Jiang; Guoyue Chen; Jirui Wang; Pengfei Qi; Zhien Pu; et al. (Theoretical and Applied Genetics, 2020)

Overexpression of LncRNA PSMG3-AS1 Distinguishes Glioblastomas from Sarcoidosis - Liusheng Chen; Guanliang Wang; Zihui Xu; Kailong Lin; Sen Mu; Yicheng Pan; Mengya Shan (Journal of Molecular Neuroscience, 2020)

Safety of azithromycin in pediatrics: a systematic review and meta-analysis - Linan Zeng; Peipei Xu; Imti Choonara; Zhenyan Bo; Xiangchen Pan; Wenyan Li; Xiaofeng Ni; Tao Xiong; Can Chen; Leshan Huang; Shamim Ahmad Qazi; Dezhi Mu; et al. (European Journal of Clinical Pharmacology, 2020)
Purpose To evaluate the toxicity of azithromycin in neonates, infants, and children. Methods A systematic review was performed for relevant studies using Medline (Ovid), PubMed, Cochrane Central Register of Controlled Trials, EMBASE, CINAHL, and International Pharmaceutical Abstracts. We calculated the pooled incidence of adverse drug reactions (ADRs) associated with azithromycin based on prospective studies (RCTs and prospective cohort studies) and analyzed the risk difference (RD) of ADRs between azithromycin and placebo or other antibiotics using meta-analysis of RCTs. Results We included 133 studies with 4243 ADRs reported in 197,675 neonates, infants, and children who received azithromycin. The safety of azithromycin as MDA in pediatrics was poorly monitored. The main ADRs were diarrhea and vomiting. In prospective non-MDA studies, the most common toxicity was gastrointestinal ADRs (938/1967; 47.7%). The most serious toxicities were cardiac (prolonged QT or irregular heart beat) and idiopathic hypertrophic pyloric stenosis (IHPS). Compared with placebo, azithromycin did not show increased risk ADRs based on RCTs (risk difference − 0.17 to 0.07). The incidence of QT prolonged was higher in the medium-dosage group (10–30 mg/kg/day) than that of low-dosage group (≤ 10 mg/kg/day) (82.0% vs 1.2%). Conclusion The safety of azithromycin as MDA needs further evaluation. The most common ADRs are diarrhea and vomiting. The risk of the most serious uncommon ADRs (cardiac-prolonged QT and IHPS) is unknown.

Current methods and applications in computational protein design for food industry - Qiuming Chen; Yaqin Xiao; Wenli Zhang; Wanmeng Mu (Critical Reviews in Food Science and Nutrition, 2020)

Dissection and validation of a QTL cluster linked to Rht-B1 locus controlling grain weight in common wheat (Triticum aestivum L.) using near-isogenic lines - Panfeng Guan; Xueyi Shen; Qing Mu; Yongfa Wang; Xiaobo Wang; Yongming Chen; Yue Zhao; Xiyong Chen; Aiju Zhao; Weiwei Mao; Yiwen Guo; Mingming Xin; et al. (Theoretical and Applied Genetics, 2020)

A novel, major, and validated QTL for the effective tiller number located on chromosome arm 1BL in bread wheat - Jiajun Liu; Huaping Tang; Xiangru Qu; Hang Liu; Cong Li; Yang Tu; Shuiqing Li; Ahsan Habib; Yang Mu; Shoufeng Dai; Mei Deng; Qiantao Jiang; et al. (Plant Molecular Biology, 2020)

Dual-Emitting N/S-Doped Carbon Dots-Based Ratiometric Fluorescent and Light Scattering Sensor for High Precision Detection of Fe(III) Ions - Zhiyan Chen; Xueqin Xu; Dongling Meng; Honglin Jiang; Yun Zhou; Shouai Feng; Zhao Mu; Yaling Yang (Journal of Fluorescence, 2020)

Analysis of melting reconstruction treatment and cement solidification on ultra-risk municipal solid waste incinerator fly ash–blast furnace slag mixtures - Zhongtao Luo; Liugang Chen; Meixiang Zhang; Lei Liu; Jun Zhao; Yuandong Mu (Environmental Science and Pollution Research, 2020)

Sources of particulate organic matter in the Chukchi and Siberian shelves: clues from carbon and nitrogen isotopes - Renming Jia; Xinyue Mu; Min Chen; Jing Zhu; Bo Wang; Xiaopeng Li; A. S. Astakhov; Minfang Zheng; Yusheng Qiu (Acta Oceanologica Sinica, 2020)

A bacterial polysaccharide biosynthesis-related gene inversely regulates larval settlement and metamorphosis of Mytilus coruscus - Li-Hua Peng; Xiao Liang; Rui-Heng Chang; Jia-Yi Mu; Hui-E Chen; Asami Yoshida; Kiyoshi Osatomi; Jin-Long Yang (Biofouling, 2020)

New land use regression model to estimate atmospheric temperature and heat island intensity in Taiwan - Chin-Yu Hsu; Uen-Ching Ng; Chiao-Ying Chen; Yu-Cheng Chen; Mu-Jean Chen; Nai-Tzu Chen; Shih-Chun Candice Lung; Huey-Jen Su; Chih-Da Wu (Theoretical and Applied Climatology, 2020)

Anti-hypertensive effects of Radix Rehmanniae and its active ingredients - Chiu-Haw Chao; Jue-Liang Hsu; Mu-Fen Chen; Ya-Hu Shih; Chia-Hui Lee; Mei-Li Wu; Chi-I Chang (Natural Product Research, 2020)

Ozone Treatment Unveils the Veil of Candida parapsilosis Infection in the Knee Joint: A Case Report and Literature Review - Guo Mu; Hongmei Liu; Milian Chen; Xiangbo Liu; Cehua Ou (Mycopathologia, 2020)

Neuroprotective effects of miR-532-5p against ischemic stroke - Jingwei Mu; Xi Cheng; Shanshan Zhong; Xiaohong Chen; Chuansheng Zhao (Metabolic Brain Disease, 2020)

The effects of inhibiting the activation of hepatic stellate cells by lignan components from the fruits of Schisandra chinensis and the mechanism of schisanhenol - Xiaoli He; Jiamei Chen; Yongping Mu; Hua Zhang; Gaofeng Chen; Ping Liu; Wei Liu (Journal of Natural Medicines, 2020)

Constrained optimization model of the volume of initial rainwater storage tank based on ANN and PSO - Shengnan He; Wenxue Chen; Xiangpeng Mu; Wei Cui (Environmental Science and Pollution Research, 2020)

Effects of the 1BL/1RS translocation on 24 traits in a recombinant inbred line population - Hang Liu; Huaping Tang; Puyang Ding; Yang Mu; Ahsan Habib; Yaxi Liu; Qiantao Jiang; Guoyue Chen; Houyang Kang; Yuming Wei; Youliang Zheng; Xiujin Lan; et al. (Cereal Research Communications, 2020)

Interaction between serine carboxypeptidase-like protein TtGS5 and Annexin D1 in developing seeds of Triticum timopheevi - Peihong Jiang; JianSheng Gao; Junyi Mu; Luning Duan; Yunsong Gu; Shichen Han; Lin Chen; Yaxuan Li; Yueming Yan; Xiaohui Li (Journal of Applied Genetics, 2020)

Analysis of stress-strain relationship of brittle rock containing microcracks under water pressure - Zhihao Li; Ziming Xiong; Haoxiang Chen; Hao Lu; Mu Huang; Chao Ma; Yiming Liu (Bulletin of Engineering Geology and the Environment, 2020)

Decreased mRNA Expressions of CD40L in Patients with Neuromyelitis Optica Spectrum Disorder - Ziyan Shi; Ling Feng; Zhiyun Lian; Ju Liu; Hongxi Chen; Qin Du; Ying Zhang; Qin Zhang; Mu Yang; Hongyu Zhou (Journal of Molecular Neuroscience, 2020)

Biomechanical Comparison of Lumbar Motion Unit Stability Following Posterior Instrumentation with Facet Spacers and Facet Screws - Mu-Yi Liu; Tsung-Ting Tsai; Lih-Huei Chen; Wen-Huang Liang; Po-Liang Lai; Ching-Lung Tai (Journal of Medical and Biological Engineering, 2020)
Purpose Lumbar posterior instrumentation for facet stabilization has become popular for the treatment of lumbar instability. The present study investigated and compared facet stabilization following lumbar posterior instrumentation with facet spacers and facet screws using porcine lumbar spines. Methods Eighteen L5–L6 lumbar motion units (LMUs) of the porcine spines were randomly divided into three groups (un-instrumented, facet-spacer and facet-screw). In the un-instrumented group (control), all ligamentous structures were preserved. In the facet-spacer group, two facet spacers were inserted into the joint spaces of the bilateral upper and lower facets. In the facet-screw group, two cannulated screws were used to transfix the bilateral upper and lower facets. With the use of a material testing machine, a gradually increasing moment of up to 6000 N-mm was generated in flexion, extension, lateral bending and torsion motions to compare facet stabilization among the groups. Results The facet-spacer group was significantly stiffer than the facet-screw group in extension ( p = 0.013), whereas the facet-screw group was significantly stiffer than the facet-spacer group in axial rotation ( p = 0.004). No statistically significant differences were observed between the two fixation techniques in flexion ( p = 0.284) and lateral bending ( p = 0.085). Conclusion Both facet-spacer and facet-screw fixation techniques significantly improve stability in a single LMU. Facet-spacer fixation provided better stabilization in extension, while facet-screw fixation provided better stabilization in axial rotation.

Identification and characterization of mRNAs and lncRNAs of a barley shrunken endosperm mutant using RNA-seq - Yaya Zou; Huaping Tang; Ting Li; Min Sun; Xiangru Qu; Jieguang Zhou; Congcong Yang; Yang Mu; Qiantao Jiang; Yaxi Liu; Guoyue Chen; Guangdeng Chen; et al. (Genetica, 2020)

Cadmium immobilization in aqueous solution by Aspergillus niger and geological fluorapatite - Christopher Uche Okolie; Haoming Chen; Yexin Zhao; Da Tian; Lin Zhang; Mu Su; Zhonquan Jiang; Zhen Li; Huixin Li (Environmental Science and Pollution Research, 2020)

An effective method for identification of three mussel species and their hybrids based on SNPs - Xingqiang Chen; Ronghua Li; Chunlin Wang; Changkao Mu; Weiwei Song; Lei Liu; Ce Shi; Pingping Zhan (Conservation Genetics Resources, 2020)

Impacts of replacement of dietary fish oil by vegetable oils on growth performance, anti-oxidative capacity, and inflammatory response in large yellow croaker Larimichthys crocea - Hua Mu; Chaoqing Wei; Yanjiao Zhang; Huihui Zhou; Ying Pan; Jia Chen; Wenbing Zhang; Kangsen Mai (Fish Physiology and Biochemistry, 2020)

The variation of motor-related brain structure and its relation to abnormal motor behaviors in end-stage renal disease patients with restless legs syndrome - Junya Mu; Xiaohui Liu; Shaohui Ma; Tao Chen; Xueying Ma; Peng Li; Dun Ding; Jixin Liu; Ming Zhang (Brain Imaging and Behavior, 2020)

Molecular identification reveals hybrids of Mytilus coruscus × Mytilus galloprovincialis in mussel hatcheries of China - Weijia Zhang; Ronghua Li; Xingqiang Chen; Chunlin Wang; Zhongqi Gu; Changkao Mu; Weiwei Song; Pingping Zhan; Ji Huang (Aquaculture International, 2020)

Correction to: Identification and validation of a major and stably expressed QTL for spikelet number per spike in bread wheat - Jian Ma; Puyang Ding; Jiajun Liu; Ting Li; Yaya Zou; Ahsan Habib; Yang Mu; Huaping Tang; Qiantao Jiang; Yaxi Liu; Guoyue Chen; Jirui Wang; et al. (Theoretical and Applied Genetics, 2020)

Flag leaf size and posture of bread wheat: genetic dissection, QTL validation and their relationships with yield-related traits - Jian Ma; Yang Tu; Jing Zhu; Wei Luo; Hang Liu; Cong Li; Shuiqin Li; Jiajun Liu; Puyang Ding; Ahsan Habib; Yang Mu; Huaping Tang; et al. (Theoretical and Applied Genetics, 2020)

Analyzing the action of evolutionarily conserved modules on HMW-GS 1Ax1 promoter activity - Luning Duan; Shichen Han; Ke Wang; Peihong Jiang; Yunsong Gu; Lin Chen; Junyi Mu; Xingguo Ye; Yaxuan Li; Yueming Yan; Xiaohui Li (Plant Molecular Biology, 2020)

Mutational signatures and mutagenic impacts associated with betel quid chewing in oral squamous cell carcinoma - Shih-Chi Su; Lun-Ching Chang; Chiao-Wen Lin; Mu-Kuan Chen; Chun-Ping Yu; Wen-Hung Chung; Shun-Fa Yang (Human Genetics, 2019)

Molecular Characterization, Tissue Distribution and Localization of Larimichthys crocea Kif3a and Kif3b and Expression Analysis of Their Genes During Spermiogenesis - Danli Mu; Chen Du; Suyan Fu; Jingqian Wang; Congcong Hou; Daojun Tang; Junquan Zhu (Journal of Ocean University of China, 2019)

Differential diagnosis of the cranial perforations on the Early Iron Age along the Ancient Silk Road in Xinjiang, China - Xiaoya Zhan; Ai-Jia Mu; Liang Chen; Qun Zhang; Yong Wu; Wanglin Hu; Hui-Yuan Yeh (Archaeological and Anthropological Sciences, 2019)
Bioarcheologists and pathologists favor trauma on the skeletons since it could reflect the human activities and interpersonal relationship in the past. In this paper, we present the pattern of two cranial perforations found on an adult male buried in the Xiaoshankou Cemetery, which was part of the Silk Road region, dating back to the early Iron Age. The specimen of interest presents two perforations on his skull, with one perforation located on the anterior part of the left parietal bone, while the other is on the occipital bone near to the lambda. The morphology of the perforations indicates perimortem traumatic lesions, probably produced by a sharp force weapon, possibly arrowhead, through one shot. The interpretation of the penetrating lesions on this cranium offers new perspectives when diagnosing perforations on the skulls in the Xinjiang region. Meanwhile, this study adds literature to the patterns of violence in Xinjiang region as well.

The Optimal Precursors for ENSO Events Depicted Using the Gradient-definition-based Method in an Intermediate Coupled Model - Bin Mu; Juhui Ren; Shijin Yuan; Rong-Hua Zhang; Lei Chen; Chuan Gao (Advances in Atmospheric Sciences, 2019)

Identification and validation of a major and stably expressed QTL for spikelet number per spike in bread wheat - Jian Ma; Puyang Ding; Jiajun Liu; Ting Li; Yaya Zou; Ahsan Habib; Yang Mu; Huaping Tang; Qiantao Jiang; Yaxi Liu; Guoyue Chen; Jirui Wang; et al. (Theoretical and Applied Genetics, 2019)

Genome-wide identification of internal reference genes for normalization of gene expression values during endosperm development in wheat - Junyi Mu; Lin Chen; Yunsong Gu; Luning Duan; Shichen Han; Yaxuan Li; Yueming Yan; Xiaohui Li (Journal of Applied Genetics, 2019)

Laboratory Experiments on an Internal Solitary Wave over a Triangular Barrier - Haidi Mu; Xu Chen; Qun Li (Journal of Ocean University of China, 2019)

Remote Detection of Varying Water Storage in Relation to Surfacial Temperature of Aral Sea - Guangyi Mu; Li Chen; Liangjun Hu; Kaishan Song (Chinese Geographical Science, 2019)

More realistic land‐use and vegetation parameters in a regional climate model reduce model biases over China - Jiaojiao Gou; Fei Wang; Kai Jin; Xingmin Mu; Deliang Chen (International Journal of Climatology, 2019)
Accurate vegetation cover data are important for realistic simulation of regional climate. The default vegetation parameters from Global Land Cover 2000, currently incorporated into global climate models and used in regional climate model RegCM, are not realistic for China, which may have contributed to serious bias in surface climate simulation. In this study, a new set of vegetation parameters considering the Plant Functional Type (PFT) fractions and the corresponding monthly leaf area index (PFT_LAI), were developed based on the land cover and MODIS LAI data sets. The regional climate model RegCM4.5 coupled with the land surface model CLM4.5 were utilized to test the performance of the new vegetation parameters by comparing simulations with observations using different surface parameters. The surface energy balance was analysed to examine the effects of changed vegetation parameters on regional climate. The results showed that the new parameters were more accurate than the GLC2000 parameters when describing the distribution of crops, grassland, and forests over China. The improved vegetation parameters reduced model biases for winter air temperature and precipitation over southern China by 0.9°C and 8%, respectively, and reduced the winter temperature and summer precipitation biases over northeastern China by approximately 0.7°C and 8%, respectively. More accurate surface albedo are the main reasons for reductions in model bias. However, certain biases, such as the cold and dry bias over the Tibetan Plateau, still remained in the simulation results using our new vegetation data.

Geosites in Karamay city, Xinjiang Uygur Autonomous Region, northwest China - Jun-Ting Qiu; Liang Qiu; Hong-Xu Mu; Wen-Xin Yang; Feng Chen; Bo-Kun Yan; Jun-Chuan Yu; He-Ming Yang (Geoheritage, 2019)

Effect of freeze-thaw cycles on uniaxial mechanical properties of cohesive coarse-grained soils - Yong-long Qu; Guo-liang Chen; Fu-jun Niu; Wan-kui Ni; Yan-hu Mu; Jing Luo (Journal of Mountain Science, 2019)

Use of near-isogenic lines to precisely map and validate a major QTL for grain weight on chromosome 4AL in bread wheat (Triticum aestivum L.) - Panfeng Guan; Na Di; Qing Mu; Xueyi Shen; Yongfa Wang; Xiaobo Wang; Kuohai Yu; Wanjun Song; Yongming Chen; Mingming Xin; Zhaorong Hu; Weilong Guo; et al. (Theoretical and Applied Genetics, 2019)

Correction to: Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosis - Da-nian Dai; Yan Li; Bo Chen; Yong Du; Shi-bing Li; Shi-xun Lu; Zhi-ping Zhao; Ai-jun Zhou; Ning Xue; Tian-liang Xia; Mu-sheng Zeng; Qian Zhong; et al. (Journal of Molecular Medicine, 2019)

Effects of water content on the shear behavior and critical state of glacial till in Tianmo Gully of Tibet, China - Gordon G. D. Zhou; Lei-lei Chen; Qing-yi Mu; Kahlil Fredrick E. Cui; Dong-ri Song (Journal of Mountain Science, 2019)

Compression characteristics of saturated re-compacted glacial tills in Tianmo Gully of Tibet, China - Lei-lei Chen; Gordon G. D. Zhou; Qing-yi Mu; Kahlil Fredrick E. Cui; Dong-ri Song (Journal of Mountain Science, 2019)

MAOA-VNTR Genotype Effects on Ventral Striatum-Hippocampus Network in Alzheimer’s Disease: Analysis Using Structural Covariance Network and Correlation with Neurobehavior Performance - Hsin-I Chang; Ya-Ting Chang; Shih-Jen Tsai; Chi-Wei Huang; Shih-Wei Hsu; Mu-En Liu; Wen-Neng Chang; Chia-Yi Lien; Shu-Hua Huang; Chen-Chang Lee; Chiung-Chih Chang (Molecular Neurobiology, 2019)

Experimental investigation on the optical remote sensing images of internal solitary waves with a smooth surface - Yuan Mei; Jing Wang; Songsong Huang; Haidi Mu; Xu Chen (Acta Oceanologica Sinica, 2019)

Identification and validation of a novel major QTL for all-stage stripe rust resistance on 1BL in the winter wheat line 20828 - Jian Ma; Nana Qin; Ben Cai; Guoyue Chen; Puyang Ding; Han Zhang; Congcong Yang; Lin Huang; Yang Mu; Huaping Tang; Yaxi Liu; Jirui Wang; et al. (Theoretical and Applied Genetics, 2019)

Genetic analysis of cob resistance to F. verticillioides: another step towards the protection of maize from ear rot - Cong Mu; Jingyang Gao; Zijian Zhou; Zhao Wang; Xiaodong Sun; Xuecai Zhang; Huafang Dong; Yanan Han; Xiaopeng Li; Yabin Wu; Yunxia Song; Peipei Ma; et al. (Theoretical and Applied Genetics, 2019)

Effects of dietary Allium mongolicum Regel polysaccharide on growth, lipopolysaccharide-induced antioxidant responses and immune responses in Channa argus - Mu-Yang Li; Xin-Ming Zhu; Xiao-Tian Niu; Xiu-Mei Chen; Jia-Xin Tian; Yi-Di Kong; Dong-Ming Zhang; Lei Zhao; Gui-Qin Wang (Molecular Biology Reports, 2019)

Novel mutations in ZP1, ZP2, and ZP3 cause female infertility due to abnormal zona pellucida formation - Zhou Zhou; Caixia Ni; Ling Wu; Biaobang Chen; Yao Xu; Zhihua Zhang; Jian Mu; Bin Li; Zheng Yan; Jing Fu; Wenjing Wang; Lin Zhao; et al. (Human Genetics, 2019)

Pedobacter pollutisoli sp. nov., Isolated from Tetrabromobisphenol A-Contaminated Soil - Yang Mu; Zhuang Ke; Chen-Xi Feng; Xiao-Wei Wang; Xiao-Wen Wang; Hong-Mei Wang; Qing Chen; Jian He (Current Microbiology, 2019)

Tripartite interactions between jasmonic/salicylic acid pathways, western flower thrips, and thrips-transmitted tomato zonate spot virus infection in Capsicuum annuum - Xue Zheng; Yong Chen; Lihua Zhao; Yongdui Chen; Limin Zheng; Kuanyu Zheng; Ye Mu; Xingyue Zhao; Yulin Gao; Jie Zhang (Arthropod-Plant Interactions, 2019)

Emergency Control Scheme for Upstream Pools of Long‐Distance Canals - Wei Cui; Xiangpeng Mu; Wenxue Chen; T.A. Stephens; B.P. Bledsoe (Irrigation and Drainage, 2019)
An emergency control scheme is proposed for pools upstream of a canal experiencing flow obstruction incidents. In order to achieve a prompt and efficient transition process, operation strategies are set out. It is suggested to switch from a constant downstream depth operation method to a constant volume operation method under qualified conditions. Based on a balanced pool operation equation and a transitional time estimation equation, a two‐step gate operation method is designed, which is compatible with the operation method of constant downstream depth and the mixed pool operation method of constant downstream depth and constant volume. The emergency control scheme is tested by simulations on the 561 km long Middle Route Project (MPR) of the South‐to‐North Water Diversion Project in China consisting of 30 pools. The constant downstream depth and mixed pool operation methods are examined. Results indicate that the control scheme operates well under the emergency situation of a flow obstruction incident. Canal flow moves promptly and effectively to the new steady state by switching to the constant volume method. Back and forth volume variation is avoided and a significant improvement is obtained in terms of transition time, while the times of check gate operation remain roughly the same. © 2018 John Wiley & Sons, Ltd.

Blockade of Endogenous Angiotensin-(1–7) in Hypothalamic Paraventricular Nucleus Attenuates High Salt-Induced Sympathoexcitation and Hypertension - Xiao-Jing Yu; Yu-Wang Miao; Hong-Bao Li; Qing Su; Kai-Li Liu; Li-Yan Fu; Yi-Kang Hou; Xiao-Lian Shi; Ying Li; Jian-Jun Mu; Wen-Sheng Chen; Wei Cui; et al. (Neuroscience Bulletin, 2019)

Permian integrative stratigraphy and timescale of China - Shuzhong Shen; Hua Zhang; Yichun Zhang; Dongxun Yuan; Bo Chen; Weihong He; Lin Mu; Wei Lin; Wenqian Wang; Jun Chen; Qiong Wu; Changqun Cao; et al. (Science China Earth Sciences, 2019)

Base cation concentrations in forest litter and topsoil have different responses to climate and tree species along elevational gradients - Feng Xue; Ming-fei Zhao; Yu-hang Wang; Mu-yi Kang; Kai-xiong Xing; Guo-yi Wang; Jing-jing Shi; Chen Chen; Yuan Jiang (Journal of Mountain Science, 2019)

Decreased autophagy was implicated in the decreased apoptosis during decidualization in early pregnant mice - Qiutong Chen; Rufei Gao; Yanqing Geng; Xuemei Chen; Xueqing Liu; Lei Zhang; Xinyi Mu; Yubin Ding; Yingxiong Wang; Junlin He (Journal of Molecular Histology, 2018)

Big Data and Situation-Aware Technology for Smarter Healthcare - Mu-Yen Chen; Edwin David Lughofer; Robi Polikar (Journal of Medical and Biological Engineering, 2018)

A 55 K SNP array-based genetic map and its utilization in QTL mapping for productive tiller number in common wheat - Jiajun Liu; Wei Luo; Nana Qin; Puyang Ding; Han Zhang; Congcong Yang; Yang Mu; Huaping Tang; Yaxi Liu; Wei Li; Qiantao Jiang; Guoyue Chen; et al. (Theoretical and Applied Genetics, 2018)

Early Mesozoic magmatism and tectonic evolution of east-central Tibet - Yanfei Chen; Zeming Zhang; Zuolin Tian; Xin Dong; Huixia Ding; Hongchen Mu; Dongyan Kang; Yunshuai Li (International Journal of Earth Sciences, 2018)

Identification and Field Evaluation of the Sex Pheromone of Orthaga achatina (Lepidoptera: Pyralidae) - Qi Yan; Hai-Dong Li; Yan Chen; Zhan-Feng Ye; Xi-Yu You; Jun Zhou; Lan-Fang Mu; Shi-Jing Liu; Xiang-Bo Kong; Sajjad Ali Khuhro; Shuang-Lin Dong (Journal of Chemical Ecology, 2018)

Strategies for lead distribution in organs of Phragmites australis (Cav.) Trin. ex Steud. (Common reed) subjected to Pb pollution in flood and drought environments - Na Zhang; Jing Chen; Zhiqiang Li; Yujie Shi; Chunsheng Mu; Zhenhua Zhang (Hydrobiologia, 2018)

Scale effect and value criterion of the permeability of the interlayer staggered zones in the basalt of Jinsha River basin, China - Zhifang Zhou; Mu Lin; Qiaona Guo; Meng Chen (Hydrogeology Journal, 2018)

Abnormal interaction between cognitive control network and affective network in patients with end-stage renal disease - Junya Mu; Tao Chen; Qianqian Liu; Dun Ding; Xueying Ma; Peng Li; Anmao Li; Mingxia Huang; Zengjun Zhang; Jixin Liu; Ming Zhang (Brain Imaging and Behavior, 2018)

Rock burst risk in an island longwall coal face by stress field - Guangjian Liu; Zonglong Mu; Jianjun Chen; Jing Yang; Jinglong Cao (Geosciences Journal, 2018)

Phylogenetic analysis and antifouling potentials of culturable fungi in mangrove sediments from Techeng Isle, China - Xiao-Yong Zhang; Wen Fu; Xiao Chen; Mu-Ting Yan; Xian-De Huang; Jie Bao (World Journal of Microbiology and Biotechnology, 2018)

Isolation and functional characterization of the SpCBF1 gene from Solanum pinnatisectum - Wenjiao Zhu; Ke Shi; Ruimin Tang; Xiaoying Mu; Jinghui Cai; Min Chen; Xiong You; Qing Yang (Physiology and Molecular Biology of Plants, 2018)

Molecular surveillance of Vittaforma-like microsporidia by a small-volume procedure in drinking water source in Taiwan: evidence for diverse and emergent pathogens - Jung-Sheng Chen; Bing-Mu Hsu; Hsin-Chi Tsai; Yu-Pin Chen; Tung-Yi Huang; Kuan-Ying Li; Dar-Der Ji; Herng-Sheng Lee (Environmental Science and Pollution Research, 2018)

Catechol-O-Methyltransferase Val158Met Polymorphism on Striatum Structural Covariance Networks in Alzheimer’s Disease - Chiung-Chih Chang; Shih-Jen Tsai; Nai-Ching Chen; Chi-Wei Huang; Shih-Wei Hsu; Ya-Ting Chang; Mu-En Liu; Wen-Neng Chang; Wan-Chen Tsai; Chen-Chang Lee (Molecular Neurobiology, 2018)

Toxicity of Chlorpyrifos and Dimethoate to the Ciliate Urostyla grandis, with Notes on Their Effects on Cell Ultrastructure - Weijie Mu; Alan Warren; Xuming Pan; Chen Ying (Journal of Ocean University of China, 2018)

RNAi-mediated SLC7A11 knockdown inhibits melanogenesis-related genes expression in rabbit skin fibroblasts - Naisu Yang; Lin Mu; Bohao Zhao; Manman Wang; Shuaishuai Hu; Bin Zhao; Yang Chen; Xinsheng Wu (Journal of Genetics, 2018)

The relationship of chromophoric dissolved organic matter parallel factor analysis fluorescence and polycyclic aromatic hydrocarbons in natural surface waters - Sijia Li; Ya’nan Chen; Jiquan Zhang; Kaishan Song; Guangyi Mu; Caiyun Sun; Hanyu Ju; Meichen Ji (Environmental Science and Pollution Research, 2018)

Efficient Using Durian Shell Hydrolysate as Low-Cost Substrate for Bacterial Cellulose Production by Gluconacetobacter xylinus - Mu-Tan Luo; Cheng Zhao; Chao Huang; Xue-Fang Chen; Qian-Lin Huang; Gao-Xiang Qi; Lan-Lan Tian; Lian Xiong; Hai-Long Li; Xin-De Chen (Indian Journal of Microbiology, 2017)

Synergistic effects of temperature and humidity on the symptoms of COPD patients - Zhe Mu; Pei-Li Chen; Fu-Hai Geng; Lei Ren; Wen-Chao Gu; Jia-Yun Ma; Li Peng; Qing-Yun Li (International Journal of Biometeorology, 2017)

The acute toxicity of bisphenol A and lignin-derived bisphenol in algae, daphnids, and Japanese medaka - Dan Li; Ran Bi; Hongxing Chen; Lei Mu; Lina Zhang; Qin Chen; Haibo Xie; Yongju Luo; Lingtian Xie (Environmental Science and Pollution Research, 2017)

Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosis - Da-nian Dai; Yan Li; Bo Chen; Yong Du; Shi-bing Li; Shi-xun Lu; Zhi-ping Zhao; Ai-jun Zhou; Ning Xue; Tian-liang Xia; Mu-sheng Zeng; Qian Zhong; et al. (Journal of Molecular Medicine, 2017)
Cystatin SN (CST1) belongs to the type 2 cystatin (CST) superfamily, which restricts the proteolytic activities of cysteine proteases. CST1 has been recently considered to be involved in the development of several human cancers. However, the prognostic significance and function of CST1 in breast cancer remains unknown. In the current study, we found that CST1 was generally upregulated in breast cancer at both mRNA and protein level. Furthermore, overall survival (OS) and disease-free survival (DFS) in the low CST1 expression subgroup were significantly superior to the high CST1 expression subgroup (OS, p < 0.001; DFS, p < 0.001), which indicated that CST1 expression level was closely correlated to the survival risk of these patients. Univariate and multivariate analyses demonstrated that CST1 expression was an independent prognostic factor, the same as ER status and nodal status. Next, CST1 overexpression promoted breast cancer cell proliferation, clonogenicity, migration, and invasion abilities. By contrast, knockdown of CST1 attenuated these malignant characteristics in breast cancer cells. Collectively, our study indicates that CST1 cannot only serve as a significant prognostic indicator but also as a potential therapeutic target for breast cancer. Key messages High CST1 expression is negatively correlated with survival of breast cancer patients. CST1 promotes cell proliferation, clone formation, and metastasis in breast cancer cells. CST1 is a novel potential prognostic biomarker and therapeutic target for breast cancer.

First detection of enteric adenoviruses genotype 41 in recreation spring areas of Taiwan - Yi-Jia Shih; Chi-Wei Tao; Hsin-Chi Tsai; Wen-Chien Huang; Tung-Yi Huang; Jung-Sheng Chen; Yi-Chou Chiu; Tsui-Kang Hsu; Bing-Mu Hsu (Environmental Science and Pollution Research, 2017)

Desulfurization with Thialkalivibrio versutus immobilized on magnetic nanoparticles modified with 3-aminopropyltriethoxysilane - Tingzhen Mu; Jixiang Zhao; Yueping Guan; Jiangnan Tian; Maohua Yang; Chen Guo; Jianmin Xing (Biotechnology Letters, 2017)

Identification and validation of reference genes for gene expression studies in sweet osmanthus (Osmanthus fragrans) based on transcriptomic sequence data - Hongna Mu; Taoze Sun; Chen Xu; Lianggui Wang; Yuanzheng Yue; Huogen Li; Xiulian Yang (Journal of Genetics, 2017)

Puerarin-7-O-glucuronide, a water-soluble puerarin metabolite, prevents angiotensin II-induced cardiomyocyte hypertrophy by reducing oxidative stress - Ning Hou; Bin Cai; Cai-Wen Ou; Zhen-Hui Zhang; Xia-Wen Liu; Mu Yuan; Gan-Jian Zhao; Shi-Ming Liu; Long-Gen Xiong; Jian-Dong Luo; Cheng-Feng Luo; Min-Sheng Chen (Naunyn-Schmiedeberg's Archives of Pharmacology, 2017)

Functional genes and thermophilic microorganisms responsible for arsenite oxidation from the shallow sediment of an untraversed hot spring outlet - Ye Yang; Yao Mu; Xian-Chun Zeng; Weiwei Wu; Jie Yuan; Yichen Liu; E. Guoji; Feng Luo; Xiaoming Chen; Hao Li; Jianing Wang (Ecotoxicology, 2017)

Geotechnical characteristics of weathered granitic gneiss with geo-hazards investigation of pit excavation in Guangzhou, China - Mu Chen; Shui-Long Shen; Huai-Na Wu; Zhi-Feng Wang; Suksun Horpibulsuk (Bulletin of Engineering Geology and the Environment, 2017)

Interaction between southern rice black-streaked dwarf virus minor core protein P8 and a rice zinc finger transcription factor - Jing Li; Nian-Jun Cai; Jin Xue; Jian Yang; Jian-Ping Chen; Heng-Mu Zhang (Archives of Virology, 2017)

Investigation on prenatal dengue infections in a dengue outbreak in Guangzhou City, China - Jie Yang; Jiawen Zhang; Qundi Deng; Junping Wang; Yunbin Chen; Xiaohong Liu; Fei Wu; Jianmin Niu; Xiaoping Mu (Infectious Diseases, 2017)

Erratum to: Diurnal and seasonal variation of the elevation gradient of air temperature in the northern flank of the western Qinling Mountain range, China - Guo-yi Wang; Ming-fei Zhao; Mu-yi Kang; Kai-xiong Xing; Yu-hang Wang; Feng Xue; Chen Chen (Journal of Mountain Science, 2017)

Screening, purification, and characterization of a novel organic solvent-tolerant esterase, Lip2, from Monascus purpureus strain M7 - Li-Jing Kang; Zi-Tong Meng; Chen Hu; Yan Zhang; Hai-Lun Guo; Qing Li; Mu Li (Extremophiles, 2017)

Diurnal and seasonal variation of the elevation gradient of air temperature in the northern flank of the western Qinling Mountain range, China - Guo-yi Wang; Ming-fei Zhao; Mu-yi Kang; Kai-xiong Xing; Yu-hang Wang; Feng Xue; Chen Chen (Journal of Mountain Science, 2017)

A high throughput method for rapid screening of chitosanase-producing fungal strain under acidic conditions - Su Ding; Gui-Guang Chen; Zhi-Qun Liang; Wei Zeng; Mu-Ming Cao; Guo-Pin Chen; Shu-Yu Xie; Wei Li (World Journal of Microbiology and Biotechnology, 2016)

Rapid Fabrication of a Cell-Seeded Collagen Gel-Based Tubular Construct that Withstands Arterial Pressure - Ho-Yi Tuan-Mu; Po-Ching Lu; Pei-Yuan Lee; Chien-Chih Lin; Chun-Jung Chen; Lynn L.H. Huang; Jia-Horng Lin; Jin-Jia Hu (Annals of Biomedical Engineering, 2016)

Non-integrating lentiviral vectors based on the minimal S/MAR sequence retain transgene expression in dividing cells - Zhen Xu; Feng Chen; Lingling Zhang; Jing Lu; Peng Xu; Guang Liu; Xuemin Xie; Wenli Mu; Yajun Wang; Depei Liu (Science China Life Sciences, 2016)

Seed predators can increase nectar volumes in an alpine daisy: but do the insects benefit? - Junpeng Mu; Yan Chen; Yulian Yang; Ronghua Fu; Hui Wang; Stephen G. Compton (Plant Ecology, 2016)

Dihydromyricetin Ameliorates 3NP-induced Behavioral Deficits and Striatal Injury in Rats - Shuhua Mu; Youlan Li; Bingbing Liu; Weiping Wang; Si Chen; Jiajia Wu; Lisi OuYang; Yaxi Zhu; Keyi Li; Mali Zhan; Zongwei Liu; Yu Jia; et al. (Journal of Molecular Neuroscience, 2016)

Baseline sensitivity and control efficacy of antibiosis fungicide tetramycin against Botrytis cinerea - Yingying Song; Leiming He; Lele Chen; Yupeng Ren; Hongbao Lu; Su Geng; Wei Mu; Feng Liu (European Journal of Plant Pathology, 2016)

Thermal and spectral characterization of anaerobic thermal behavior patterns in a lacustrine sediment core - Fei Guo; Yunsong Mu; Cheng Chen; Haiqing Liao; Yingchen Bai (Environmental Science and Pollution Research, 2016)

Antidepressant-like effects of standardized gypenosides: involvement of brain-derived neurotrophic factor signaling in hippocampus - Rong-Hao Mu; Xiao-Yan Fang; Shuang-Shuang Wang; Cheng-Fu Li; Shao-Mei Chen; Xue-Mei Chen; Qing Liu; Yu-Cheng Li; Li-Tao Yi (Psychopharmacology, 2016)

Propofol Prevents Hippocampal Neuronal Loss and Memory Impairment in Cerebral Ischemia Injury Through Promoting PTEN Degradation - Xin Chen; Ye-Mu Du; Feng Xu; Dai Liu; Yuan-Lin Wang (Journal of Molecular Neuroscience, 2016)

A graphical model for haloanhydrite components and P-wave velocity: A case study of haloanhydrites in Amu Darya Basin - Tong-Cui Guo; Hong-Jun Wang; Long-Xin Mu; Xing-Yang Zhang; Zhi Ma; Yu Tian; Hao-Chen Li (Applied Geophysics, 2016)

Cloning, expression and characterization of a novel cold-active and organic solvent-tolerant esterase from Monascus ruber M7 - Hailun Guo; Yan Zhang; Yanchun Shao; Wanping Chen; Fusheng Chen; Mu Li (Extremophiles, 2016)

Impacts of large natural disasters on regional income - Jianhong E. Mu; Yong Chen (Natural Hazards, 2016)

Methylenebisnicotiflorin: a rare methylene-bridged bisflavonoid glycoside from ripe Pu-er tea - Mu-Ke Tao; Min Xu; Han Zhang; Hui Chen; Chang Liu; Hong-Tao Zhu; Dong Wang; Chong-Ren Yang; Ying-Jun Zhang (Natural Product Research, 2016)

Experimental and numerical studies on the sample area and skin effect of the three-rod time domain reflectometry probe - T.L.T. Zhan; Q.Y. Mu; Y.M. Chen (European Journal of Environmental and Civil Engineering, 2016)

Identification of potential cargo proteins of transportin protein AtTRN1 in Arabidopsis thaliana - Bo Yan; Xiaoning Wang; Zhenyu Wang; Ni Chen; Changjun Mu; Kaili Mao; Lirong Han; Wei Zhang; Heng Liu (Plant Cell Reports, 2016)

Measurements of nitrous acid (HONO) in urban area of Shanghai, China - François Bernard; Mathieu Cazaunau; Benoît Grosselin; Bin Zhou; Jun Zheng; Peng Liang; Yujie Zhang; Xingnan Ye; Véronique Daële; Yujing Mu; Renyi Zhang; Jianmin Chen; et al. (Environmental Science and Pollution Research, 2016)

Sublethal concentration of benzothiazole adversely affect development, reproduction and longevity of Bradysia odoriphaga (Diptera: Sciaridae) - Yunhe Zhao; Peng Zhang; Yongbiao Zhai; Chengyu Chen; Qiuhong Wang; Jingkun Han; Zhengqun Zhang; Feng Liu; Wei Mu (Phytoparasitica, 2016)

Vascular endothelial growth factor-C protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis - Xu-guang Chen; Yan-xia Lv; Dan Zhao; Lei Zhang; Fei Zheng; Jian-Ye Yang; Xiao-lin Li; Lu Wang; Lin-Yun Guo; Ya-mu Pan; Yu-wen Yan; Shi-You Chen; et al. (Molecular and Cellular Biochemistry, 2016)

Molecular characterization of Beclin 1 in rare minnow (Gobiocypris rarus) and its expression after waterborne cadmium exposure - Xiao-Hong Liu; Zhi-Jian Wang; Dong-Ming Chen; Mu-Fei Chen; Xing-Xing Jin; Jing Huang; Yao-Guang Zhang (Fish Physiology and Biochemistry, 2016)

Baseline sensitivity and efficacy of the sterol biosynthesis inhibitor triflumizole against Botrytis cinerea - Yingying Song; Datong Xu; Hongbao Lu; Leiming He; Lele Chen; Junan Shao; Chunmei Xu; Wei Mu; Feng Liu (Australasian Plant Pathology, 2016)

Degradation of p-Nitrophenol in Soil by Dielectric Barrier Discharge Plasma - Rui Li; Yanan Liu; Yu Sun; Wenjuan Zhang; Ruiwen Mu; Xiang Li; Hong Chen; Pin Gao; Gang Xue; Stephanie Ognier (Water, Air, & Soil Pollution, 2015)