LncRNA XIST contributes to epithelial–mesenchymal transformation in posterior opacity via regulating miR-98-5p/COL5A2 axis and PI3K/Akt/FOXO1 pathway - Junxia Sun; Shasha Han; Ping Chen (Molecular & Cellular Toxicology, 2023)

Biogas residue biochar still had ecological risks to the ultisol: evidence from soil bacterial communities, organic carbon structures, and mineralization - Ping Cong; Xuebo Zheng; Lanfang Han; Liying Chen; Jintao Zhang; Wenjing Song; Jianxin Dong; Xiaogang Ma (Journal of Soils and Sediments, 2023)

Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3β and Nrf2/NQO1 pathways - Sun Xiao-Lei; Xia Tian-Shuang; Jiang Yi-Ping; Wang Na-Ni; Xu Ling-Chuan; Han Ting; Xin Hai-Liang (Journal of Natural Medicines, 2023)

The Detection and Imaging of pH Values in Living Cells with Hemicyanine Based Colorimetric Mitochondria-Targeted Fluorescent Probe - Zhengcheng Chen; Dan Wu; Han Yang; Ping Zou; Guangtu Wang (Journal of Fluorescence, 2023)

Study on the Coal–rock Ratio Effect of Asymmetric Deformation and Failure of the Gob–side Coal–rock Roadway in Gently Inclined Coal Seam - Lin Gao; Yexing Shen; Ping Liu; Yongyin Wang; Zhenqian Ma; Xiangtao Kang; Sen Han (Geotechnical and Geological Engineering, 2023)

Biomarker selection strategies based on compound stability in wastewater-based epidemiology - Zhihan Gao; Ping Li; Han Lin; Wenting Lin; Yuan Ren (Environmental Science and Pollution Research, 2023)

A symbiosis between Euploea butterflies and yeasts - Wan-Rou Lin; Yi-Ping Chang; Hui-Lin Wu; I-Cheng Hsu; Pi-Han Wang (Symbiosis, 2023)

The landscape of aging - Yusheng Cai; Wei Song; Jiaming Li; Ying Jing; Chuqian Liang; Liyuan Zhang; Xia Zhang; Wenhui Zhang; Beibei Liu; Yongpan An; Jingyi Li; Baixue Tang; et al. (Science China Life Sciences, 2022)

Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson’s Disease - Cheng-Jie Li; Li-Ge Zhang; Lu-Bing Liu; Meng-Qi An; Li-guo Dong; Han-Ying Gu; Yong-Ping Dai; Fen Wang; Cheng-Jie Mao; Chun-Feng Liu (Molecular Neurobiology, 2022)

Hepatic HRC induces hepatocyte pyroptosis and HSCs activation via NLRP3/caspase-1 pathway - Jingwen Wu; Mingyu Zhang; Suhong Xia; Ping Han; Kai Zhao; Kaixin Peng; Wangdong Zhou; Dean Tian; Jiazhi Liao; Jingmei Liu (Journal of Molecular Medicine, 2022)

Acute Toxicity of a Novel anti-fouling Material Additive DCOIT to Marine Chlorella sp - Jin-Chuang Ru; Xue-Li Zhao; Zhi-Han Cao; Cheng-Zhuang Chen; Ping Li; Zhi-Hua Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Effects of Dietary Tannic Acid on Growth, Digestion, Immunity and Resistance to Ammonia Stress, and Intestinal Microbial Community in Pacific White Shrimp (Litopenaeus vannamei) - Han Gong; Zhen Qin; Zhao Chen; Jitao Li; Zhiqiang Chang; Jian Li; Ping Chen (Fishes, 2022)
Tannic acid (TA) has great potential as a new feed additive. In this study, we investigated the effects of dietary TA on growth, digestion, nonspecific immunity, and resistance to ammonia stress and intestinal microbiota in Litopenaeus vannamei. The shrimp were fed diets containing different levels of TA: 0 mg/kg (TA-0), 200 mg/kg (TA-200), 400 mg/kg (TA-400), and 800 mg/kg (TA-800) for 56 days, followed by acute ammonia stress for 48 h. The results showed that dietary TA increased the survival rate of the TA-800 group. Dietary TA could improve the morphology of the hepatopancreas and intestinal tissues. After feeding different levels of TA for 56 days, the activities of amylase (AMS) and trypsin (Tryp) were increased, but the activity of lipase (LPS) was decreased. The activities of T-AOC, SOD, and PPO were higher in the hepatopancreas of the three TA treatment groups (p

The effect of reservoir expansion from underground karst cave to surface reservoir on water quality in southwestern China - Meng Lu; Xiao-Dan Wang; Fu-Jun Yue; Zi-Han Liu; Zhi-Yu Shi; Ping Zhang (Environmental Science and Pollution Research, 2022)

Genetic diversity, lineage divergence, and demography of Diaphanosoma dubium (Crustacea: Cladocera) on Hainan Island, China - Ping Liu; Xiaoli Zhang; Qi Huang; Eric Zeus C. Rizo; Henri J. Dumont; Bo-Ping Han (Hydrobiologia, 2022)

Flocculation of Chlorella vulgaris–induced algal blooms: critical conditions and mechanisms - Ping Zhang; Sihan Zhu; Chao Xiong; Bin Yan; Zhikang Wang; Kai Li; Irumva Olivier; Han Wang (Environmental Science and Pollution Research, 2022)

Effects of the Seleno-Chitosan on Daily Gain, Wool Yield, and Blood Parameter in the Chinese Merino Sheep - Qionglian Zhang; Yong Han; Yang Yang; Ping zhou; Xiaoyun Shen (Biological Trace Element Research, 2022)

EST-SSR marker-based investigation on genetic diversity and genetic structure of Juglans mandshurica Maxim. in Shandong Province of China - Zihao Wang; Hao Zhang; Boqiang Tong; Biao Han; Dan Liu; Ping Zhang; Dechang Hu (Genetic Resources and Crop Evolution, 2022)

Characteristics of timberline and treeline altitudinal distribution in Mt. Namjagbarwa and their geographical interpretation - Hao-xiang Mu; Fang Han; Bai-ping Zhang; Tian Liang; Zhi-yong Wang; Zhe Wang (Journal of Mountain Science, 2022)

Feasibility Studies of Nebulized SARS-CoV-2 Neutralizing Antibody in Mice and Cynomolgus Monkeys - Jilei Jia; Zhaojuan Yin; Xiao Zhang; Huimin Li; Dan Meng; Qianqian Liu; Hongfang Wang; Meng Han; Shixiang Suo; Yan Liu; Ping Hu; Chunyun Sun; et al. (Pharmaceutical Research, 2022)
Purpose Neutralizing antibodies, administrated through intravenous infusion, have shown to be highly efficacious in treating mild and moderate COVID-19 caused by SARS-CoV-2 infection in the lung. However, antibodies do not transport across the plasma-lung barrier efficiently, and up to 100 mg/kg dose was used in human causing significant supply and cost burdens. This study was to explore the feasibility of nebulized antibodies inhalation delivery as an alternative route. Methods HB27, a potent RBD-specific humanized monoclonal antibody (Zhu et al. in National Sci Rev. 8:nwaa297, 2020), showed excellent protection against SARS-CoV-2 in animal model and good safety profile in clinical studies. The pharmacokinetics and preliminary safety of HB27 administrated through the respiratory tract were studied in mice and cynomolgus monkeys here. Results At a single 5 mg/kg dose, the peak HB27 concentration in mice pulmonary epithelial lining fluid (ELF) reached 857.8 μg/mL, 670-fold higher than the PRNT 90 value of 1.28 μg/mL, and maintained above PRNT 90 over 240 h. In contrast, when administrated by intravenous injection at a 5 mg/kg dose, the antibody concentrations in mice ELF were below PRNT 90 value throughout, and were about 50-fold lower than that in the serum. In cynomolgus monkeys administrated with a single dose through inhalation, the antibody concentration in ELF remained high within 3 days. No drug-related safety concerns were observed in the studies. Conclusions The study demonstrated that nebulized neutralizing antibody delivery though inhalation could be a more efficient and efficacious alternative approach for treating COVID-19 and other respiratory infectious diseases, and warrants further evaluation in clinical studies.

The Role of Post-Translational Modifications on the Structure and Function of Tau Protein - Haiqiong Ye; Yue Han; Ping Li; Zhengding Su; Yongqi Huang (Journal of Molecular Neuroscience, 2022)

Microfluidic preparation of a novel phoxim nanoemulsion pesticide against Spodoptera litura - Zong-Nan Li; Yu-Xuan Zhang; Zhi-Ang Zhang; Lian-Han Pan; Ping Li; Yan Xu; Sheng Sheng; Fu-An Wu; Jun Wang (Environmental Science and Pollution Research, 2022)

Chemometric-Guided Exploration of Marine Anti-Neurofibroma Leads - Lo-Yun Chen; Bo-Rong Peng; Guan-Yi Lai; Hao-Jui Weng; Mohamed El-Shazly; Chun-Han Su; Jui-Hsin Su; Ping-Jyun Sung; Chung-Ping Liao; Kuei-Hung Lai (Frontiers in Marine Science, 2022)
In-depth analysis of metabolomics diversity of marine species through advanced mass spectrometric analysis is one of the most promising new tools for the development of marine drugs against mild and life-threatening diseases. Neurofibromas are a common type of tumor in the peripheral nervous system. Currently, there are very limited treatment options for neurofibromas. In our course of exploring potential therapeutic agents for neurofibroma treatment, the multi-informative molecular networking (MIMN) approach was proposed. The MIMNs of the Lendenfeldia sp. sponge extract and sub-fractions were established according to their inhibitory activity against several inflammatory chemokines (CCL3, CCL4, CCL5, CXCL1, CXCL8, and CXCL10) in neurofibroma cell line hTERT-NF1-ipNF95.11b-C (CRL-3390). The visualized MIMN revealed the anti-inflammatory potential of scalarane-enriched fractions, and the follow-up annotation and isolation led to the identification of a scalarane, 24-methyl-12,24,25-trioxoscalar-16-en-22-oic acid (2). Our results revealed that the most abundant scalarane (2) dominated the anti-chemokine effect of Lendenfeldia sp. extract together with other scalaranes, indicating the potential application of sponge-derived scalaranes to be developed as therapeutic agents for neurofibromas.

Rhodoflexus caldus gen. nov., sp. nov., a new member of the phylum Bacteroidota isolated from a hot spring sediment - Ze-Tao Liu; Lan Liu; Wen-Dong Xian; Zheng-Han Lian; Jun-Yi Dai; Bao-Zhu Fang; Meng-Meng Li; Ai-Ping Lv; Zhen-Hao Luo; Jian-Yu Jiao; Wen-Jun Li (Antonie van Leeuwenhoek, 2022)

Truncation of the N-terminus of cardiac troponin I initiates adaptive remodeling of the myocardial proteosome via phosphorylation of mechano-sensitive signaling pathways - Chad M. Warren; Monika Halas; Paul H. Goldspink; Han-Zhong Feng; Anthony W. Herren; Beata M. Wolska; Pieter P. de Tombe; Jian-Ping Jin; R. John Solaro (Molecular and Cellular Biochemistry, 2022)

Genome wide association analysis of acid detergent fiber content of 206 forage sorghum (Sorghum bicolor (L.) Moench) accessions - Hao Niu; Yuanhuai Han; Junai Ping; Yubin Wang; Xin Lv; Jianqiang Chu (Genetic Resources and Crop Evolution, 2022)

C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population - Feifei Han; Lu Qian; Yi Zhang; Ping Liu; Rui Li; Mingwei Chen (Functional & Integrative Genomics, 2022)

Effects of long-term exposure of norfloxacin on the HPG and HPT axes in juvenile common carp - Si-Qi Zhang; Xue-Li Zhao; Shu-Wen He; Shao-Ying Xing; Zhi-Han Cao; Ping Li; Zhi-Hua Li (Environmental Science and Pollution Research, 2022)

Evaluation of genetic variants in nucleosome remodeling and deacetylase (NuRD) complex subunits encoding genes and gastric cancer susceptibility - Yujuan Zhang; Guoquan Tao; Ping Liu; Kai Lu; Zhichao Han; Hanting Liu; Mulong Du; Meilin Wang; Haiyan Chu; Zhengdong Zhang (Archives of Toxicology, 2022)

Functional connections between bird eggshell stiffness and nest characteristics through risk of egg collision in nests - Chih‐Ming Hung; Shu‐Han Tsao; Pei‐Lin Chiang; Shang‐Ping Wu; Mao‐Ning Tuanmu; Jia‐Yang Juang (Ecology Letters, 2022)
Eggs and nests are two critical traits for the ecological success of birds. Their functional interactions, however, remain unclear. Here, we examined the functional connections between egg stiffness and nest attachment, site and structure for 1350 avian species. We revealed high eggshell stiffness for eggs in nests with a pensile attachment, located on non‐tree vegetation or having a domed shape, suggesting that birds produce stiffer eggs in response to higher egg‐collision risk in unstable or enclosed nests. Interdependence models suggested that the evolution of eggshell stiffness was more likely to be driven by than drive that of nest characters. Our results implied a trade‐off between investment in competing for established nesting niches and producing stiff eggs to explore novel niches with high collision risk, possibly mediated by predation or thermoregulation. This study highlights an overlooked connection between nests and eggshells that may have broadened the ecological niches of birds.

Determination of fluoroquinolones in chicken muscle by molecularly imprinted graphitic carbon nitride-based solid-phase extraction and ultra-performance liquid chromatography - Su Han Wang; Ning Ma; Xiao Huan Zang; Shuai Hua Zhang; Jian Ping Wang; Ning Peng Wu (Food Additives & Contaminants: Part A, 2022)

One new piperazinedione isolated from a mangrove-derived fungus Aspergillus niger JX-5 - Meng Bai; Yue Wang; Ting Liu; Yu-Xing Lian; Qi-Qi Bai; Xiao-Ping Song; Chang-Ri Han; Cai-Juan Zheng; Guang-Ying Chen (Natural Product Research, 2022)

TREM2 and CD163 Ameliorate Microglia-Mediated Inflammatory Environment in the Aging Brain - Xue Han; Yu-Jia Liu; Bin-Wen Liu; Zheng-Liang Ma; Tian-Jiao Xia; Xiao-Ping Gu (Journal of Molecular Neuroscience, 2022)

Analysis on ecological status and spatial–temporal variation of Tamarix chinensis forest based on spectral characteristics and remote sensing vegetation indices - Jin Wang; Ping Han; Yanhua Zhang; Jinyu Li; Linxu Xu; Xue Shen; Zhigang Yang; Sisi Xu; Guangxue Li; Feiyong Chen (Environmental Science and Pollution Research, 2022)

Approximate analytical solution for seepage field of drained tunnel in vertically stratified phreatic aquifer - Wei Meng; Chuan He; Fang-yin Wu; Wen-bo Yang; Hao Kou; Zi-han Zhou; De-ping Guo; Hai-long Meng (Journal of Mountain Science, 2022)

Genome-based reclassification of the genus Meiothermus along with the proposal of a new genus Allomeiothermus gen. nov - Jian-Yu Jiao; Zheng-Han Lian; Ze-Tao Liu; Lan Liu; Meng-Meng Li; Ai-Ping Lv; Wen-Dong Xian; Ting Zhou; Zhitang Lyu; Nimaichand Salam; Wen-Jun Li (Antonie van Leeuwenhoek, 2022)

Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities - Ying-Ying Chen; Jiang-Ping Hou; Ling Huang; Afsar Khan; Fei-Fei Xing; Xiao-Han Zhang; De-Feng Han; Shi-Li Yan; Gui-Dong Cao; Qi-Yang Jiao; Dejie Liu; Xuwei Zhu; et al. (Natural Product Research, 2022)

Superpixel segmentation of PolSAR images based on improved local iterative clustering - Binbin Han; Ping Han; Zheng Cheng (International Journal of Remote Sensing, 2022)

Curcumin Inhibits Cell Damage and Apoptosis Caused by Thapsigargin-Induced Endoplasmic Reticulum Stress Involving the Recovery of Mitochondrial Function Mediated by Mitofusin-2 - He-Yan Zhou; Yu-Ying Sun; Ping Chang; Han-Chang Huang (Neurotoxicity Research, 2022)

Involvement of Opioid Peptides in the Analgesic Effect of Spinal Cord Stimulation in a Rat Model of Neuropathic Pain - Fu-Jun Zhai; Song-Ping Han; Tian-Jia Song; Ran Huo; Xing-Yu Lan; Rong Zhang; Ji-Sheng Han (Neuroscience Bulletin, 2022)

Targeting GATA1 and p2x7r Locus Binding in Spinal Astrocytes Suppresses Chronic Visceral Pain by Promoting DNA Demethylation - Yan-Yan Wu; Hai-Long Zhang; Xiaomin Lu; Han Du; Yong-Chang Li; Ping-An Zhang; Guang-Yin Xu (Neuroscience Bulletin, 2022)
Irritable bowel syndrome is a gastrointestinal disorder of unknown etiology characterized by widespread, chronic abdominal pain associated with altered bowel movements. Increasing amounts of evidence indicate that injury and inflammation during the neonatal period have long-term effects on tissue structure and function in the adult that may predispose to gastrointestinal diseases. In this study we aimed to investigate how the epigenetic regulation of DNA demethylation of the p2x7r locus guided by the transcription factor GATA binding protein 1 (GATA1) in spinal astrocytes affects chronic visceral pain in adult rats with neonatal colonic inflammation (NCI). The spinal GATA1 targeting to DNA demethylation of p2x7r locus in these rats was assessed by assessing GATA1 function with luciferase assay, chromatin immunoprecipitation, patch clamp, and interference in vitro and in vivo . In addition, a decoy oligodeoxynucleotide was designed and applied to determine the influence of GATA1 on the DNA methylation of a p2x7r CpG island. We showed that NCI caused the induction of GATA1, Ten-eleven translocation 3 (TET3), and purinergic receptors (P2X7Rs) in astrocytes of the spinal dorsal horn, and demonstrated that inhibiting these molecules markedly increased the pain threshold, inhibited the activation of astrocytes, and decreased the spinal sEPSC frequency. NCI also markedly demethylated the p2x7r locus in a manner dependent on the enhancement of both a GATA1–TET3 physical interaction and GATA1 binding at the p2x7r promoter. Importantly, we showed that demethylation of the p2x7r locus (and the attendant increase in P2X7R expression) was reversed upon knockdown of GATA1 or TET3 expression, and demonstrated that a decoy oligodeoxynucleotide that selectively blocked the GATA1 binding site increased the methylation of a CpG island in the p2x7r promoter. These results demonstrate that chronic visceral pain is mediated synergistically by GATA1 and TET3 via a DNA-demethylation mechanism that controls p2x7r transcription in spinal dorsal horn astrocytes, and provide a potential therapeutic strategy by targeting GATA1 and p2x7r locus binding.

Synthesis and anticancer activity of Boc-Gly-Pro dipeptide-annonaceous acetogenin prodrugs targeting fibroblast activation protein or other hydrolytic enzymes - Jing-Fang Shi; Ping Wu; Han-Xiang Li; Xiao-Yi Wei; Zi-Hua Jiang (Medicinal Chemistry Research, 2022)

The genetic engineering of glycine betaine synthesis in tobacco improves the resistance of the photosynthetic apparatus to drought stress - Gui-Ping Wang; Xiao-Min Xue; Xing-hong Yang; Ru Chen; Xue-Ping Han (Plant Biotechnology Reports, 2022)

Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma - Peipei Han; Shu Wu; Limei Li; Danping Li; Jun Zhao; Haishan Zhang; Yifang Wang; Xuemin Zhong; Zhe Zhang; Ping Li; Liudmila Matskova; Xiaoying Zhou (Genes & Genomics, 2022)

A new isoflavone from the fruits of Ficus auriculata and its antibacterial activity - Tai-Ming Shao; Hai-Xia Liao; Xiao-Bao Li; Guang-Ying Chen; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2022)

The biogeographical history of giant earthworms of the Metaphire formosae species group (Clitellata: Megascolecidae) in Taiwan and the Ryukyu Archipelago, with the description of a new species from Yonagunijima, Southern Ryukyus - Huei-Ping Shen; Chih-Han Chang; Hidetoshi Ota (Organisms Diversity & Evolution, 2022)

Experimental investigation of propagation and run-up of rockslide- generated impulse waves in a curved mountain reservoir - Linfeng Han; Pingyi Wang; Ping Mu; Qingyang Ren; Yun Liu (Natural Hazards, 2022)

Analysis of Influencing Factors of Temperature Field in Freezing Construction of Metro Connecting Passage - Ping Xu; Shuqi Han; Yu Xing (Geotechnical and Geological Engineering, 2022)

A comparison of the reproducibility of regional precipitation properties simulated respectively by weather generators and stochastic simulation methods - Luhua Yang; Ping-an Zhong; Feilin Zhu; Yufei Ma; Han Wang; Jieyu Li; Chengjing Xu (Stochastic Environmental Research and Risk Assessment, 2022)

The effect of methyltestosterone (MT) on sex differentiation and growth in juvenile yellow perch (Perca flavescens) - Rafidah Othman; Xiao-Jun Ron; Hong Yao; Paul O’Bryant; Dean Rapp; Jing-Chen Pei; Hong-Juan Wu; Han-Ping Wang (Fish Physiology and Biochemistry, 2022)

Mortality outcomes and survival patterns of patients with myeloproliferative neoplasms in Malaysia - Yee Yee Yap; Jameela Sathar; Kian Boon Law; Sen Mui Tan; Ngee Siang Lau; Tee Chuan Ong; Ai Sim Goh; Teng Keat Chew; Soo Min Lim; See Guan Toh; Xavier Yoon Han Sim; Padmini Menon; et al. (Cancer Causes & Control, 2022)

Effects of environmental factors on plant functional traits across different plant life forms in a temperate forest ecosystem - Xiaoqin Cheng; Tain Ping; Zuzheng Li; Tian Wang; Hairong Han; Howard E. Epstein (New Forests, 2022)

Combined effects of predicted climate and land use changes on future hydrological droughts in the Luanhe River basin, China - Xu Chen; Ruiguang Han; Ping Feng; Yongjie Wang (Natural Hazards, 2022)

Correction to: Toward a phylogeny and biogeography of Diaphanosoma (Crustacea: Cladocera) - Henri J. Dumont; Bo-Ping Han; Fei Fei Guo; Hua Chen; Dan Cheng; Ping Liu; Lei Xu; La-Orsri Sanoamuang; Arnola C. Rietzler; Shaolin Xu; Andy Vierstraete; Manuel Elias-Gutierrez (Aquatic Ecology, 2021)

Toward a phylogeny and biogeography of Diaphanosoma (Crustacea: Cladocera) - Henri J. Dumont; Bo-Ping Han; Fei Fei Guo; Hua Chen; Dan Cheng; Ping Liu; Lei Xu; La-Orsri Sanoamuang; Arnola C. Rietzler; Shaolin Xu; Andy Vierstraete; Manuel Elias-Gutierrez (Aquatic Ecology, 2021)

Development of microsatellite markers for Diaphanosoma dubium (Crustacea, Cladocera) and application to seasonal population dynamics - Ping Liu; Shao-Lin Xu; Jian Liao; Henri J. Dumont; Bo-Ping Han (Aquatic Ecology, 2021)

Ultraviolet photolysis of four typical cardiovascular drugs: mechanisms, influencing factors, degradation pathways, and toxicity trends - Senwen Ping; Wenting Lin; Anchen Liu; Zhihan Gao; Han Lin; Yuan Ren (Environmental Science and Pollution Research, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Pleosporalins H and I, two new heptaketides from the endophytic fungus Pleosporales sp. F46 by using OSMAC strategy - Hong-Xia Yang; Xiao-Ping Peng; Han Gao; Hui-Min Zhang; Zi-Ru Wang; Gang Li; Hong-Xiang Lou (Natural Product Research, 2021)

Nitrogen removal processes coupled with nitrification in coastal sediments off the north East China Sea - Yongkai Chang; Guoyu Yin; Lijun Hou; Min Liu; Yanling Zheng; Ping Han; Hongpo Dong; Xia Liang; Dengzhou Gao; Cheng Liu (Journal of Soils and Sediments, 2021)

Community structure and abundance of comammox Nitrospira in Chongming eastern intertidal sediments - Dongyao Sun; Min Liu; Lijun Hou; Mengyue Zhao; Xiufeng Tang; Qiang Zhao; Jun Li; Ping Han (Journal of Soils and Sediments, 2021)

Globular adiponectin inhibits osteoblastic differentiation of vascular smooth muscle cells through the PI3K/AKT and Wnt/β-catenin pathway - Yun Zhou; Li-Long Wei; Rui-Ping Zhang; Cheng-Wu Han; Yongtong Cao (Journal of Molecular Histology, 2021)
Lipid metabolism is closely related to the improvement of vascular calcification (VC) in chronic kidney disease (CKD). Globular adiponectin (gAd) has been reported to be involved in the development of VC in CKD, but the detailed regulatory role remains unclear. The present study is aimed to investigate the biological function and the underlying regulation mechanism of gAd in the process of VC during CKD. Vascular smooth muscle cells (VSMCs) calcification was determined by Alizarin Red S staining. Protein signaling related with VC was tested by western blotting. The expression and intracellular localization of runt-related transcription factor 2 (Runx2) was detected by immunofluorescence and uraemic rat with VC was established by a two-step nephrectomy. Combined with the results of Alizarin Red S staining, we discovered that β-glycerophosphate (β-Gp)-induced the osteoblastic differentiation of VSMCs was significantly reversed by gAd treatment. Along with the VSMCs calcification and the increase of Runx2 in β-Gp-exposed VSMCs, the activities of protein kinase B (AKT) and Wnt/β-catenin pathway were enhanced, but that were counteracted by the exposure of gAd in rat and human VSMCs. After administration with agonists of the Wnt (SKL2001) and AKT (SC79), there appeared more osteoblastic differentiation and higher expression of Runx2 in gAd-treated VSMCs, but showing lower impact in the presence of SC79 than that in the presence of SKL2001. In the in vivo experiments, intravenous injection of gAd also significantly inhibited VC and Runx2 level in uraemic rat in a dose-dependent manner, possibly through regulating Wnt/β-catenin pathway. This study demonstrates that gAd ameliorates osteoblastic differentiation of VSMCs possibly by blocking PI3K/AKT and Wnt/β-catenin signaling transduction. The findings provide an important foundation for gAd in treating VC in kidney diseases.

Diversity and arsenic-metabolizing gene clusters of indigenous arsenate-reducing bacteria in high arsenic groundwater of the Hetao Plain, Inner Mongolia - Yanhong Wang; Dazhun Wei; Ping Li; Zhou Jiang; Han Liu; Chun Qing; Helin Wang (Ecotoxicology, 2021)

Stable isotopes (δ2H) in feathers identify non-breeding origins of the endangered Jankowski’s Bunting - Zheng Han; Hai-Tao Wang; Kevin J. Kardynal; Keith A. Hobson; Wei-Ping Shang; li-shi Zhang; Yun-lei Jiang; Frédéric Jiguet (Journal of Ornithology, 2021)

A comprehensive analysis of gorilla-specific LINE-1 retrotransposons - Soyeon Jeon; Songmi Kim; Man Hwan Oh; Ping Liang; Wanxiangfu Tang; Kyudong Han (Genes & Genomics, 2021)

The Extraction and Analysis of Deformation Features of Hualien Earthquake Based on Sentinel-1A/B SAR Data - Jin Wang; Ping Han; Guangxue Li (Journal of the Indian Society of Remote Sensing, 2021)

Methane Concentration in the Heartwood of Living Trees and Estimated Methane Emission on Stems in Upland Forests - Zhi-Ping Wang; Huan-Long Li; Hong-Hui Wu; Shi-Jie Han; Jian-Hui Huang; Xi-Mei Zhang; Xing-Guo Han (Ecosystems, 2021)

Seasonal variation of flavonoid metabolites in leaves of Liquidambar formosana ‘Nanlinhong’ trees revealed by UPLC-ESI–MS/MS - Jiu-Xin Lai; Fu-Rong Lin; Ping Huang; Wen-Ying Guo; Lie-Bao Han; Yong-Qi Zheng (Brazilian Journal of Botany, 2021)

Correlation of CD38 expression with the progression of hemorrhagic fever with renal syndrome - Han-Dong Zhao; Yan-Ping Li; Wei-Wei Zhao; Peng Li; Hong-Li Liu (Archives of Virology, 2021)

Triterpene saponins from tea seed pomace ( Camellia oleifera Abel) and their cytotoxic activity on MCF-7 cells in vitro - Xin-Fu Zhang; Ying-Ying Han; Tai-Mei Di; Li-Ping Gao; Tao Xia (Natural Product Research, 2021)

Recycle of synthetic calcium fluoride and waste sulfuric acid to produce electronic grade hydrofluoric acid - Min-Fa Lin; Jhong-Lin Wu; Ken-Lin Chang; Wen-Jhy Lee; Chih-Ping Chang; Yung-Chang Lin; Po-Han Chen (Environmental Science and Pollution Research, 2021)

Cloud-Based Multidimensional Parallel Dynamic Programming Algorithm for a Cascade Hydropower System - Yufei Ma; Ping-an Zhong; Bin Xu; Feilin Zhu; Jieyu Li; Han Wang; Qingwen Lu (Water Resources Management, 2021)

Characteristics of RNA alternative splicing and its potential roles in ginsenoside biosynthesis in a single plant of ginseng, Panax ginseng C.A. Meyer - Yilai Han; Lei Zhu; Li Li; Yanfang Wang; Mingzhu Zhao; Kangyu Wang; Chunyu Sun; Jing Chen; Lingyu Liu; Ping Chen; Jun Lei; Yi Wang; et al. (Molecular Genetics and Genomics, 2021)

Interactive effect of water level and flushing rate on population dynamics of a harmful cyanobacterial species: Raphidiopsis raciborskii - Quehui Tang; Lamei Lei; Li Zhao; Jiguang Gu; Lijuan Xiao; Bo-Ping Han (Ecotoxicology, 2021)

Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment - Rui-Yuan Zhang; Jie-Bai Tu; Rui-Tu Ran; Wen-Xuan Zhang; Qiang Tan; Ping Tang; Tao Kuang; Shu-Qun Cheng; Cheng-Zhi Chen; Xue-Jun Jiang; Chang Chen; Ting-Li Han; et al. (Neurotoxicity Research, 2021)

Decreased Plasma Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Levels are Linked with Disease Severity in Patients with Liver Cirrhosis - Lian-Ying Yang; Ji-Ping Hou; En-Kun Han; Gang Qiao; Li-Bin Liu; Xue-Bo Men (International Journal of Peptide Research and Therapeutics, 2021)

Cladosporine A, a new indole diterpenoid alkaloid with antimicrobial activities from Cladosporium sp. - Xue Han; Xue-Feng Bao; Chuan-Xi Wang; Jun Xie; Xiao-Jun Song; Ping Dai; Guo-Dong Chen; Dan Hu; Xin-Sheng Yao; Hao Gao (Natural Product Research, 2021)

Aristololactam alkaloids from the roots of Dasymaschalon rostratum - Yue Wang; Wen-Hao Chen; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2021)

Evidence-based Customized Ankle-Foot Orthosis with Energy Storage - Chih-Chun Lin; Chien-Hsien Yeh; Yi-Chun Tsai; Li-Chieh Kuo; Hsiu-Yun Hsu; Ping-Han Chuang; Kai Chang; Fong-Chin Su (Journal of Medical and Biological Engineering, 2021)

Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling - Li Zhang; Lu Wang; Han Xiao; Hui Gan; Hui Chen; Shuyue Zheng; Dan Jian; Xuan Zhai; Ning Jiang; Zhao Jing; Ping Liang (Journal of Molecular Medicine, 2021)

The adaptability of typical precipitation ensemble prediction systems in the Huaihe River basin, China - Han Wang; Ping-an Zhong; Fei-lin Zhu; Qing-wen Lu; Yu-fei Ma; Sun-yu Xu (Stochastic Environmental Research and Risk Assessment, 2021)

Altered BMP-Smad4 signaling causes complete cleft palate by disturbing osteogenesis in palatal mesenchyme - Nan Li; Jing Liu; Han Liu; Shangqi Wang; Ping Hu; Hailing Zhou; Jing Xiao; Chao Liu (Journal of Molecular Histology, 2021)

Dapagliflozin suppresses ER stress and protects doxorubicin-induced cardiotoxicity in breast cancer patients - Wei-Ting Chang; Yu-Wen Lin; Chung-Han Ho; Zhih-Cherng Chen; Ping-Yen Liu; Jhih-Yuan Shih (Archives of Toxicology, 2021)

Correction to: 4-Phenylbutyric acid protects against vasculitic peripheral neuropathy induced by ischaemia–reperfusion through attenuating endoplasmic reticulum stress - Cay‑Huyen Chen; Ping‑Chen Shih; Han‑Yu Lin; Po‑Kai Wang; Po‑Ting Pan; Ching‑Wei Chuang; Ming‑Chang Kao (Inflammopharmacology, 2020)

Nano spirulina dietary supplementation augments growth, antioxidative and immunological reactions, digestion, and protection of Nile tilapia, Oreochromis niloticus, against Aeromonas veronii and some physical stressors - Hiam Elabd; Han-Ping Wang; Adel Shaheen; Aya Matter (Fish Physiology and Biochemistry, 2020)

Pseudo-Magnetotelluric 2D Inversion Technology of Magnetic-Source Transient Electromagnetics - Zi-qiang Han; Shu-ping Jiang; Fengbing (Applied Geophysics, 2020)

Zircon U-Pb-Hf isotopes and geochemistry of Jurassic igneous rocks from the southern Zhangguangcai Range, NE China: constraints on magmatism, petrogenesis and tectonic implications - Zuo-Zhen Han; Xiang Ren; Hans-Peter Schertl; Xu-Ping Li; Zhi-Gang Song; Qing-Xiang Du; Chao Han; Wen-Jian Zhong; Li-Hua Gao (International Geology Review, 2020)

What factors determine the mass elevation effect of the Tibetan Plateau? - Fang Han; Li Wan; Hong-zhi Wu; Bai-ping Zhang; Lan Gao; Ge Song (Journal of Mountain Science, 2020)

Risk analysis of reservoir floodwater utilization coupling meteorological and hydrological uncertainties - Qingwen Lu; Ping-an Zhong; Bin Xu; Feilin Zhu; Han Wang; Yufei Ma (Stochastic Environmental Research and Risk Assessment, 2020)

Zooplankton in a continuous waterscape: environmental and spatial factors shaping spring zooplankton community structure in a large canyon reservoir at the tropic of cancer - Eric Zeus C. Rizo; Ping Liu; Haiyu Niu; Yang Yang; Qiuqi Lin; Rey Donne S. Papa; Henri J. Dumont; Bo-Ping Han (Hydrobiologia, 2020)

Pre-symptomatic local brain activity and functional connectivity alterations in nasopharyngeal carcinoma patients who developed radiation encephalopathy following radiotherapy - You-ming Zhang; Jian-ming Gao; Hong Zhou; Li Li; Li-zhi Liu; Zai-de Han; Xiao-ping Yi; Wei-hua Liao (Brain Imaging and Behavior, 2020)

Comparative iTRAQ Proteomics Reveals Multiple Effects of Selenium Yeast on Dairy Cows in Parturition - Zhi-hua Ren; Li-peng Bai; Liu-hong Shen; Zheng-zhong Luo; Zi-han Zhou; Zhi-cai Zuo; Xiao-ping Ma; Jun-liang Deng; Ya Wang; Sheng-yu Xu; Yu-heng Luo; Sui-zhong Cao; et al. (Biological Trace Element Research, 2020)

N-acyl-homoserine lactones (AHLs) in intertidal marsh: diversity and potential role in nitrogen cycling - Zongxiao Zhang; Yanling Zheng; Ping Han; Hongpo Dong; Xia Liang; Guoyu Yin; Dianming Wu; Yi Yang; Sitong Liu; Min Liu; Lijun Hou (Plant and Soil, 2020)

Rainfall-induced landslide in loess area, Northwest China: a case study of the Changhe landslide on September 14, 2019, in Gansu Province - Haojie Wang; Ping Sun; Shuai Zhang; Shuai Han; Xiaobin Li; Tao Wang; Qiang Guo; Peng Xin (Landslides, 2020)

NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy - Han Xiao; Hui Chen; Rong Jiang; Li Zhang; Lu Wang; Hui Gan; Ning Jiang; Jing Zhao; Xuan Zhai; Ping Liang (Journal of Molecular Medicine, 2020)

Combined effects of green manure returning and addition of sewage sludge compost on plant growth and microorganism communities in gold tailings - Yan-Jun Ai; Fu-Ping Li; Hai-Hong Gu; Xiao-Jie Chi; Xue-Tao Yuan; Dong-Yun Han (Environmental Science and Pollution Research, 2020)

Effects of different treatments on genes related to polysaccharide content in Dendrobium huoshanense - Jun Dai; Xing-bang Han; Nai-fu Chen; Cun-wu Chen; Nai-dong Chen; Xiang-wen Song; Xue-ping Jiang; Yu-juan Wang (Brazilian Journal of Botany, 2020)

Identification and evaluation of tobacco cytoplasmic male sterile line Nta(gla)S K326 generated from asymmetric protoplast fusion of Nicotiana glauca and N. tabacum followed by backcrossing with N. tabacum K326 - Xue-Jun Chen; Zhi-Jun Tong; Bing-Guang Xiao; Yong-Ping Li; Fang-Chan Jiao; Yong Li; Tao Pang; Dun-Huang Fang; Xing-Fu Wu; Yi-Han Zhang; He Xie; Ge Bai; et al. (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Responses of Primary Afferent Fibers to Acupuncture-Like Peripheral Stimulation at Different Frequencies: Characterization by Single-Unit Recording in Rats - Ran Huo; Song-Ping Han; Feng-Yu Liu; Xiao-Jing Shou; Ling-Yu Liu; Tian-Jia Song; Fu-Jun Zhai; Rong Zhang; Guo-Gang Xing; Ji-Sheng Han (Neuroscience Bulletin, 2020)

Life-history responses of Daphnia sinensis simultaneously exposed to Microcystis aeruginosa and Cylindrospermopsis raciborskii - Lamei Lei; Haitang Huang; Liang Peng; Yang Yang; Lijuan Xiao; Bo-Ping Han (Ecotoxicology, 2020)

Species diversity and seasonal dynamics of filamentous cyanobacteria in urban reservoirs for drinking water supply in tropical China - Yang Yang; Xunhao Zheng; Quehui Tang; Jiguang Gu; Lamei Lei; Bo-Ping Han (Ecotoxicology, 2020)

A remote sensing monitoring method for alpine grasslands desertification in the eastern Qinghai-Tibetan Plateau - Qian Kuang; Quan-zhi Yuan; Ji-chong Han; Rong Leng; Yu-shuang Wang; Ke-hong Zhu; Shuo Lin; Ping Ren (Journal of Mountain Science, 2020)

The implications of hippocampal neurogenesis in adolescent rats after status epilepticus: a novel role of notch signaling pathway in regulating epileptogenesis - Ping Yuan; Wei Han; Lingling Xie; Li Cheng; Hengsheng Chen; Jin Chen; Li Jiang (Cell and Tissue Research, 2020)

Biological Protective Effects Against Vibrio Infections in Grouper Larvae Using the Strombidium sp. NTOU1, a Marine Ciliate Amenable for Scaled-Up Culture and With an Excellent Bacteriovorous Ability - Hung-Yun Lin; Wei-Yu Yeh; Sheng-Fang Tsai; Kuo-Ping Chiang; John Han-You Lin; Che-Chia Tsao; Han-Jia Lin (Frontiers in Marine Science, 2020)

Seasonal Deformation of Permafrost in Wudaoliang Basin in Qinghai-Tibet Plateau Revealed by StaMPS-InSAR - Ping Lu; Jiangping Han; Tong Hao; Rongxing Li; Gang Qiao (Marine Geodesy, 2020)

Pictalignans D-F, three new neolignan derivatives from Selaginella picta - Fei Cheng; Zhen-Xing Zou; Ping-Sheng Xu; Shui-Han Zhang; Yan Zhang; Cai-Ping Yao; Kang-Ping Xu; Gui-Shan Tan (Natural Product Research, 2020)

Characterization of brain microstructural abnormalities in cirrhotic patients without overt hepatic encephalopathy using diffusion kurtosis imaging - Qing Sun; Wenliang Fan; Yuan Liu; Yan Zou; Natalie Wiseman; Zhifeng Kou; Ping Han (Brain Imaging and Behavior, 2020)
Cirrhosis is a major public health concern. However, little is known about the neurobiological mechanisms underlying brain microstructure alterations in cirrhotic patients. The purpose of this prospective study was to investigate brain microstructural alterations in cirrhosis with or without minimal hepatic encephalopathy (MHE) and their relationship with patients’ neurocognitive performance and disease duration using voxel-based analysis of diffusion kurtosis imaging (DKI). DKI data were acquired from 30 cirrhotic patients with MHE, 31 patients without MHE (NMHE) and 59 healthy controls. All DKI-derived parametric maps were compared across the three groups to investigate their group differences. Correlation analyses were further performed to assess relationships between altered imaging parameters and clinical data. Voxel-based analysis of DKI data results showed that MHE/NMHE patients had increased radial diffusivity, axial diffusivity (AD) and mean diffusivity in addition to decreased axial kurtosis (AK) and fractional anisotropy of kurtosis in several regions. Compared to controls, these regions were primarily the cingulum, temporal and frontal cortices. The DKI metrics (i.e., AK and AD) were correlated with clinical variables in the two patient groups. In conclusion, DKI is useful for detecting brain microstructural abnormalities in MHE and NMHE patients. Abnormal DKI parameters suggest alterations in brain microstructural complexity in cirrhotic patients, which may contribute to the neurobiological basis of neurocognitive impairment. These results may provide additional information on the pathophysiology of cirrhosis.

Fupyrones A and B, two new α -pyrones from an endophytic fungus, Fusarium sp. F20 - Han Gao; Gang Li; Xiao-Ping Peng; Hong-Xiang Lou (Natural Product Research, 2020)

Carboxymethylation and acetylation of the polysaccharide from Cordyceps militaris and their α-glucosidase inhibitory activities - Yuan-Yuan Ren; Peng-Peng Sun; Ying-Ping Ji; Xiao-Ting Wang; Shu-Han Dai; Zhen-Yuan Zhu (Natural Product Research, 2020)

Microbial methane production is affected by secondary metabolites in the heartwood of living trees in upland forests - Huan-Long Li; Xi-Mei Zhang; Feng-Dan Deng; Xing-Guo Han; Chun-Wang Xiao; Shi-Jie Han; Zhi-Ping Wang (Trees, 2020)

MiR-125a-5p Regulates Vitamin D Receptor Expression in a Mouse Model of Experimental Autoimmune Encephalomyelitis - Han-Chun Long; Rui Wu; Chun-Feng Liu; Fei-Long Xiong; Zu Xu; Dian He; Yi-Fan Zhang; Bing Shao; Ping-An Zhang; Guang-Yin Xu; Lan Chu (Neuroscience Bulletin, 2020)

Front Cover - Wei Wang; Jie Wang; Francis M. P. Choi; Ping Ding; Xiao‐xu Li; Guo‐dong Han; Meng‐wen Ding; Minquan Guo; Xiong‐wei Huang; Wei‐xiang Duan; Zhi‐yuan Cheng; Zhi‐yuan Chen; et al. (Global Ecology and Biogeography, 2020)

Global warming and artificial shorelines reshape seashore biogeography - Wei Wang; Jie Wang; Francis M. P. Choi; Ping Ding; Xiao‐xu Li; Guo‐dong Han; Meng‐wen Ding; Minquan Guo; Xiong‐wei Huang; Wei‐xiang Duan; Zhi‐yuan Cheng; Zhi‐yuan Chen; et al. (Global Ecology and Biogeography, 2020)
Aim Rapid anthropogenic warming coupled with changes in land use is altering the distributions of species, with consequences for ecosystem functioning and services. It is crucial to evaluate species range shifts based on understanding of the interaction of temperature with non‐climatic factors such as habitat availability and dispersal potential. Here, we aim to investigate roles of environmental temperature, habitat availability and population connectivity on the distributions of hard‐shore intertidal animals. We further examine potential roles of extensive artificial seawall construction in enabling poleward expansion of species in China, thus reshaping coastal biogeography. Location Chinese coast. Time period 2013–2017. Major taxa studied Intertidal invertebrates. Methods We took an integrative approach encompassing distributional ecology, thermal physiology, molecular genetics, heat budget modelling and larval dispersal to elucidate how interacting multiple drivers, including temperature, habitat availability and larval dispersal, determine distributions of hard‐shore invertebrates, focusing on what sets their range edges at a boundary between biogeographic provinces. Results Our results untangle the complex interactions of global climate change with the impacts of regional scale coastal development. Temperature, larval transport and habitat availability are the major proximate factors controlling the range limits of coastal marine species. The artificial shorelines provide suitable habitats for hard‐shore species on the Yangtze River Delta, and minimum temperature in winter is an important factor setting the new northern range limit of these hard‐shore species along the Chinese coast. Main conclusions In the face of global warming and global sprawl of marine hard infrastructure, species distributions, community structures and biogeographic patterns are experiencing dramatic changes. The combined influence of multiple human stressors including climate change and artificial shorelines can be evaluated by using a multidisciplinary framework, including ecological distribution, physiological sensitivity of species to these stressors, and the role of dispersal in maintaining population connectivity.

Unsupervised classification for PolSAR images based on multi-level feature extraction - Ping Han; Binbin Han; Xiaoguang Lu; Runmin Cong; Dandan Sun (International Journal of Remote Sensing, 2020)

Research on Application of Transient Electromagnetic Method in Hydraulic Fracturing - Dong-ming Zhang; Han Yang; Zi Rao; Zhong-yu Ou; Ping Tang (Geotechnical and Geological Engineering, 2020)

New anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3 - Xu Pang; Li-Ming Wang; You-Cai Zhang; Li-Ping Kang; He-Shui Yu; Guan-Wei Fan; Li-Feng Han (Natural Product Research, 2019)

Removal of various contaminants from water by renewable lignocellulose-derived biosorbents: a comprehensive and critical review - Hai Nguyen Tran; Hoang Chinh Nguyen; Seung Han Woo; Tien Vinh Nguyen; Saravanamuthu Vigneswaran; Ahmad Hosseini-Bandegharaei; Jörg Rinklebe; Ajit Kumar Sarmah; Andrei Ivanets; Guilherme Luiz Dotto; Tho Truong Bui; Ruey-Shin Juang; et al. (Critical Reviews in Environmental Science and Technology, 2019)

Development of real-time PCR for quantification of Cylindrospermopsis raciborskii cells and potential cylindrospermopsin-producing genotypes in subtropicalreservoirs of southern China - Lamei Lei; Minting Lei; Yan Lu; Liang Peng; Bo-Ping Han (Journal of Applied Phycology, 2019)

Epigenetic modification enhances ergot alkaloid production of Claviceps purpurea - Jing-Jing Chen; Meng-Yao Han; Ting Gong; Yun-Ming Qiao; Jin-Ling Yang; Ping Zhu (Biotechnology Letters, 2019)

Ultrahigh Temperature Metamorphic Record of Pelitic Granulites in the Huangtuyao Area of the Huai’an Complex, North China Craton - Shaoting Ma; Xu-Ping Li; Hao Liu; Fanmei Kong; Han Wang (Journal of Earth Science, 2019)

Multi‐model analysis of climate impacts on plant photosynthesis in China during 2000–2015 - Hao Yan; Shao‐Qiang Wang; Jun‐Bang Wang; Yun Cao; Ling‐Ling Xu; Men‐Xin Wu; Lu Cheng; Liu‐Xi Mao; Feng‐Hua Zhao; Xian‐Zhou Zhang; Yun‐Fen Liu; Yan‐Fen Wang; et al. (International Journal of Climatology, 2019)
Differences, arising from differences in gross primary production (GPP) model structures and driving forces, have fuelled arguments concerning interannual changes of GPP in China since 2000. To better investigate the interannual variability of GPP and its covariance with climate factors in China, this study adopted a multi‐model analysis based on three GPP models (i.e., Terrestrial Ecosystem Carbon flux model [TEC], Breathing Earth System Simulator model [BESS], and MOD17 GPP model). The results show that annual GPP in China increased by 0.021–0.057 Pg C year −1 from 2000 to 2015 attributable to atmospheric‐CO 2 fertilization effects and favourable climate change, that is, increasing precipitation ( P r ) and temperature ( T a ). However, northern China and southern China had a large difference in the amplitude of these GPP changes; annual GPP increased by 0.017–0.039 Pg C year −1 in northern China but only 0.001–0.018 Pg C year −1 in southern China. Northern China and southern China occupy contrasting climate zones and this contrast produced different interannual variability of GPP through different mechanisms. Northern China has a dry climate with GPP changes sensitive to P r . As a result, more P r along with higher T a in northern China produced the strong uptrend of GPP from 2000 to 2015. In contrast, southern China has a wet climate with its GPP sensitive to solar radiation and T a . For the interval of 2000–2015, decreasing radiation plus drought exerted a negative influence on GPP in southern China. This study highlights the diverse mechanisms in which climate change affects GPP in dry and wet climate zones. A robust multi‐model analysis is preferred to reduce uncertainties arising from a single GPP model and its driving data.

Complete genome sequences of five prunus necrotic ringspot virus isolates from Inner Mongolia of China and comparison to other PNRSV isolates around the world - Shuang Song; Ping-ping Sun; Ya-han Chen; Qiang Ma; Xiao-yun Wang; Ming-min Zhao; Zheng-nan Li (Journal of Plant Pathology, 2019)

Netrin-1 promotes the collective cell migration of liver cancer cells in a 3D cell culture model - Ping Han; Jingmei Liu; Yu Lei; Zhuoying Lin; Dean Tian; Wei Yan (Journal of Physiology and Biochemistry, 2019)

One new Lignan derivative from the fruiting bodies of Ganoderma lipsiense - Meng Bai; Shou-Yuan Wu; Wen-Fei Zhang; Xiao-Ping Song; Chang-Ri Han; Cai-Juan Zheng; Guang-Ying Chen (Natural Product Research, 2019)

Deubiquitylatinase inhibitor b-AP15 induces c-Myc-Noxa-mediated apoptosis in esophageal squamous cell carcinoma - Beibei Sha; Xiaoyu Chen; Han Wu; Miaomiao Li; Jianxiang Shi; Longhao Wang; Xingge Liu; Ping Chen; Tao Hu; Pei Li (Apoptosis, 2019)

Exotic Spartina alterniflora invasion alters soil nitrous oxide emission dynamics in a coastal wetland of China - Dengzhou Gao; Lijun Hou; Xiaofei Li; Min Liu; Yanling Zheng; Guoyu Yin; Yi Yang; Cheng Liu; Ping Han (Plant and Soil, 2019)

DNA methylation and mRNA expression of COL6A3 in antler mesenchyme of female and male reindeer - Jian-Cheng Zhai; Ruo-Bing Han; Sheng-Nan Wang; Qiang-Hui Wang; Yan-Ling Xia; Wei-Shi Liu; Ya-Jie Yin; He-Ping Li (Genes & Genomics, 2019)

Numerical simulation of ground motion amplification in Modong area, Lushan - Chao Han; Jiashun Yu; Wei-Zu Liu; Jian-Long Yuan; Xiao-Bo Fu; Xiao-Ping Hou (Applied Geophysics, 2019)

Biologically active oligostilbenes from the stems of Vatica mangachapoi and chemotaxonomic significance - Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Chang-Ri Han; Xiao-Ping Song (Natural Product Research, 2019)

4-Phenylbutyric acid protects against vasculitic peripheral neuropathy induced by ischaemia–reperfusion through attenuating endoplasmic reticulum stress - Cay-Huyen Chen; Ping-Chen Shih; Han-Yu Lin; Po-Kai Wang; Po-Ting Pan; Ching-Wei Chuang; Ming-Chang Kao (Inflammopharmacology, 2019)

Anti-secretogranin III therapy of oxygen-induced retinopathy with optimal safety - Fen Tang; Michelle E. LeBlanc; Weiwen Wang; Dan Liang; Ping Chen; Tsung-Han Chou; Hong Tian; Wei Li (Angiogenesis, 2019)

A comprehensive analysis of the Baboon-specific full-length LINE-1 retrotransposons - Wooseok Lee; Minhoon Choi; Songmi Kim; Wanxiangfu Tang; Dong Hee Kim; Heui-Soo Kim; Ping Liang; Kyudong Han (Genes & Genomics, 2019)

New isolates from leaves of Nicotiana tabacum and their biological activities - Shanzhai Shang; Jianlian Shi; Jianguo Tang; Juxing Jiang; Wei Zhao; Xudong Zheng; Ping Lei; Jingmei Han; Chengya Wang; Dalin Yuan; Guangyu Yang; Yongkuan Chen; et al. (Natural Product Research, 2019)

The Tibetan Plateau Surface-Atmosphere Coupling System and Its Weather and Climate Effects: The Third Tibetan Plateau Atmospheric Science Experiment - Ping Zhao; Yueqing Li; Xueliang Guo; Xiangde Xu; Yimin Liu; Shihao Tang; Wenming Xiao; Chunxiang Shi; Yaoming Ma; Xing Yu; Huizhi Liu; La Jia; et al. (Journal of Meteorological Research, 2019)

Pseudofrancisella aestuarii gen. nov., sp. nov., a novel member of the family Francisellaceae isolated from estuarine seawater - Min-Ling Zheng; Jian-Yu Jiao; Lei Dong; Ming-Xian Han; Liang-Hui Li; Min Xiao; Cha Chen; Ping-Hua Qu; Wen-Jun Li (Antonie van Leeuwenhoek, 2019)

Furofuran lignans and alkaloids from Clinacanthus nutans - Hong-Zhang Diao; Wen-Hao Chen; Jian Cao; Tai-Ming Shao; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2019)

A new norisoprenoid from the leaves of Ficus pumila - Meng Bai; Yue Cai; Shou-Yuan Wu; Xiao-Ping Song; Guang-Ying Chen; Cai-Juan Zheng; Chang-Ri Han (Natural Product Research, 2019)

Application of different single extraction procedures for assessing the bioavailability of heavy metal(loid)s in soils from overlapped areas of farmland and coal resources - Ping Luo; Xin Xiao; Xiaoxuan Han; Yu Ma; Xiaofei Sun; Jiachao Jiang; Hui Wang (Environmental Science and Pollution Research, 2019)

Epidemiological trends and virological traits of hepatitis B virus infection in pregnant women and neonates - Ting-Ting Peng; Qiu-E Cai; Min Yang; Shao-Ping Chen; Feng Chen; Miao Wang; Ling Peng; Gary Wong; Chen-Guang Shen; Wen-Bing Cheng; Sai-Yun Liu; Ya-Bai Peng; et al. (Archives of Virology, 2019)

Inhibition of thymocyte autophagy-associated CD4+T thymopoiesis is involved in asthma susceptibility in mice exposed to caffeine prenatally - Han-xiao Liu; Hui-yi Yan; Wen Qu; Xiao Wen; Li-fang Hou; Wen-hao Zhao; Jie Ping (Archives of Toxicology, 2019)

The antitoxin MqsA homologue in Pseudomonas fluorescens 2P24 has a rewired regulatory circuit through evolution - Yong Wang; Si‐Ping Zhang; Meng‐Yuan Zhang; Megan L. Kempher; Ding‐Ding Guo; Jian‐Ting Han; Xuanyu Tao; Yi Wu; Li‐Qun Zhang; Yong‐Xing He (Environmental Microbiology, 2019)
Summary The mqsRA operon encodes a toxin–antitoxin pair that was characterized to participate in biofilm and persister cell formation in Escherichia coli . Notably, the antitoxin MqsA possesses a C‐terminal DNA‐binding domain that recognizes the [5’‐AACCT(N) 2‐4 AGGTT‐3′] motif and acts as a transcriptional regulator controlling multiple genes including the general stress response regulator RpoS. However, it is unknown how the transcriptional circuits of MqsA homologues have changed in bacteria over evolutionary time. Here, we found mqsA in Pseudomonas fluorescens ( PfmqsA ) is acquired through horizontal gene transfer and binds to a slightly different motif [5′‐TACCCT(N) 3 AGGGTA‐3′], which exists upstream of the PfmqsRA operon. Interestingly, an adjacent GntR‐type transcriptional regulator, which was termed AgtR, is under negative control of PfMqsA. It was further demonstrated that PfMqsA reduces production of biofilm components through AgtR, which directly regulates the pga and fap operons involved in the synthesis of extracellular polymeric substances. Moreover, through quantitative proteomics analysis, we showed AgtR is a highly pleiotropic regulator that influences up to 252 genes related to diverse processes including chemotaxis, oxidative phosphorylation and carbon and nitrogen metabolism. Taken together, our findings suggest the rewired regulatory circuit of PfMqsA influences diverse physiological aspects of P. fluorescens 2P24 via the newly characterized AgtR.

Skinfold thickness for rivastigmine patch application in Alzheimer’s disease - Ping-Song Chou; Kai-Ming Jhang; Ling-Chun Huang; Wen-Fu Wang; Yuan-Han Yang (Psychopharmacology, 2019)

Suppression of miR-93-5p inhibits high-risk HPV-positive cervical cancer progression via targeting of BTG3 - Jie Li; Zhao-Ping Chu; Hua Han; Yuan Zhang; Fei Tian; Jun-Qin Zhang; Xiang-Hua Huang (Human Cell, 2019)

Characteristics of single atmospheric particles in a heavily polluted urban area of China: size distributions and mixing states - Li Li; Qiyuan Wang; Xu Zhang; Yuanyuan She; Jiamao Zhou; Yang Chen; Ping Wang; Suixin Liu; Ting Zhang; Wenting Dai; Yongming Han; Junji Cao (Environmental Science and Pollution Research, 2019)

The short-term effects of outdoor temperature on blood pressure among children and adolescents: finding from a large sample cross-sectional study in Suzhou, China - Jia Hu; Hui Shen; Chen-gang Teng; Di Han; Guang-ping Chu; Yi-kai Zhou; Qi Wang; Bo Wang; Jing-zhi Wu; Qi Xiao; Fang Liu; Hai-bing Yang (International Journal of Biometeorology, 2019)

Ambient air pollution and the risk of stillbirth: a population-based prospective birth cohort study in the coastal area of China - Hongyan Zang; Han Cheng; Wenya Song; Mei Yang; Ping Han; Chunxiao Chen; Rui Ding (Environmental Science and Pollution Research, 2019)

Synthesis and biological evaluation of novel SIPI-7623 derivatives as farnesoid X receptor (FXR) antagonists - Si-Yun Nian; Guo-Ping Wang; Zheng-Li Jiang; Ying Xiao; Mo-Han Huang; Yi-Huan Zhou; Xiang-Duan Tan (Molecular Diversity, 2019)

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease - Chia-Chia Lee; Ching-Pang Chang; Chun-Jung Lin; Hsing-Lin Lai; Yu-Han Kao; Sin-Jhong Cheng; Hui-Mei Chen; Yu-Ping Liao; Emilie Faivre; Luc Buée; David Blum; Jim-Min Fang; et al. (Molecular Neurobiology, 2018)

Exogenous Brassinosteroid Enhances Plant Defense Against Colletotrichum gloeosporioides by Activating Phenylpropanoid Pathway in Camellia sinensis L. - Lan Zhang; Golam Jalal Ahammed; Xin Li; Ji-Peng Wei; Yang Li; Peng Yan; Li-Ping Zhang; Wen-Yan Han (Journal of Plant Growth Regulation, 2018)

Characterizing the Mass Elevation Effect across the Tibetan Plateau - Fang Han; Bai-ping Zhang; Fang Zhao; Li Wan; Jing Tan; Tian Liang (Journal of Mountain Science, 2018)

Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice - Guang-Jiang Shi; Jie Zheng; Xiao-Xu Han; Ya-Ping Jiang; Zhi-Mei Li; Jing Wu; Qing Chang; Yang Niu; Tao Sun; Yu-Xiang Li; Zhen Chen; Jian-Qiang Yu (Cell and Tissue Research, 2018)

Model tests on thermo-mechanical behavior of an improved energy pile - Han-long Liu; Cheng-long Wang; Gang-qiang Kong; Charles W.W. Ng; Ping Che (European Journal of Environmental and Civil Engineering, 2018)

A new12-membered lactone from the stems of Ficus auriculata - Tai-Ming Shao; Cai-Juan Zheng; Xiao-Bao Li; Guang-Ying Chen; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2018)

Development of an Autism Subtyping Questionnaire Based on Social Behaviors - Fan-Chao Meng; Xin-Jie Xu; Tian-Jia Song; Xiao-Jing Shou; Xiao-Li Wang; Song-Ping Han; Ji-Sheng Han; Rong Zhang (Neuroscience Bulletin, 2018)

A corn straw-based diet increases release of inflammatory cytokines in peripheral blood mononuclear cells of dairy cows - Yan-yi Che; Xiao-jing Xia; Bo-ping He; Yuan-yuan Gao; Wen-bo Ren; Hong-tao Liu; Jian-fang Liu; Ting-hao Huang; Wen-yu Han; Lian-cheng Lei (Journal of Zhejiang University-SCIENCE B, 2018)

Diversity and abundance of arsenic methylating microorganisms in high arsenic groundwater from Hetao Plain of Inner Mongolia, China - Yanhong Wang; Ping Li; Zhou Jiang; Han Liu; Dazhun Wei; Helin Wang; Yanxin Wang (Ecotoxicology, 2018)

Gallaecimonas mangrovi sp. nov., a novel bacterium isolated from mangrove sediment - Wei-Yan Zhang; Ye Yuan; Deng-Quan Su; Xiao-Ping He; Shuai-Bo Han; Slava S. Epstein; Shan He; Min Wu (Antonie van Leeuwenhoek, 2018)

Bioactive furanocoumarins from the stems and leaves of Clausena hainanensis - Yan-Lei Ma; Chao Zhang; Wan-Hui Zhao; Shi Shi; Dan-Nv He; Pan Zhang; Xiao-Hong Liu; Ting-Ting Han; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2018)

Docking study and antiosteoporosis effects of a dibenzylbutane lignan isolated from Litsea cubeba targeting Cathepsin K and MEK1 - Wei Peng; Hui Shen; Bing Lin; Ping Han; Changhui Li; Qiaoyan Zhang; Bingzhu Ye; Khalid Rahman; Hailiang Xin; Luping Qin; Ting Han (Medicinal Chemistry Research, 2018)

Spatial heterogeneity of spring phytoplankton in a large tropical reservoir: could mass effect homogenize the heterogeneity by species sorting? - Yang Yang; Haiyu Niu; Lijuan Xiao; Qiuqi Lin; Bo-Ping Han; Luigi Naselli-Flores (Hydrobiologia, 2018)

Low-Cd tomato cultivars (Solanum lycopersicum L.) screened in non-saline soils also accumulated low Cd, Zn, and Cu in heavy metal-polluted saline soils - Zhi-Min Xu; Xiao-Qi Tan; Xiu-Qin Mei; Qu-Sheng Li; Chu Zhou; Li-Li Wang; Han-Jie Ye; Ping Yang (Environmental Science and Pollution Research, 2018)

Novel antidepressant effects of Paeonol alleviate neuronal injury with concomitant alterations in BDNF, Rac1 and RhoA levels in chronic unpredictable mild stress rats - Xiu-Ling Zhu; Jing-Jing Chen; Fei Han; Chuan Pan; Ting-Ting Zhuang; Ya-Fei Cai; Ya-Ping Lu (Psychopharmacology, 2018)

Estimation of mass elevation effect and its annual variation based on MODIS and NECP data in the Tibetan Plateau - Fang Han; Bai-ping Zhang; Fang Zhao; Bing Guo; Tian Liang (Journal of Mountain Science, 2018)

Risk factors, outcomes and genotypes of carbapenem-nonsusceptible Klebsiella pneumoniae bloodstream infection: a three-year retrospective study in a large tertiary hospital in Northern China - Si-Han Zheng; Sheng-Ji Cao; Hui Xu; Dan Feng; Li-Ping Wan; Guang-Jie Wang; Xiao-Guang Xiao (Infectious Diseases, 2018)

De novo transcriptome analysis of an albino mutant Pasphiopedilum pacific shamrock reveals reduced expression of genes related to chloroplast biosynthesis and division - Han Li; Hua Cao; Rong-pei Yu; Zhen Miao; Ji-hua Wang; Su-Ping Qu; Qiang Yuan; Shen-chong Li (Horticulture, Environment, and Biotechnology, 2018)

Thermal reaction norms of a subtropical and a tropical species of Diaphanosoma (cladocera) explain their distribution - Franja Pajk; Jiexiang Zhang; Bo‐Ping Han; Henri J. Dumont (Limnology and Oceanography, 2018)
Species distribution boundaries are often associated with aspects of climate and modified by competitive interactions. In the tropical region, Diaphanosoma is the most diverse genus of Cladocera. Diaphanosoma dubium is widely distributed in China, whereas the tropical Diaphanosoma excisum is restricted to the islands off the south China coast. The mean temperature of the coldest month at the northern limit of its distribution is 15°C. We studied the effect of temperature (10–40°C) on life history traits of clones from 16 populations of D. dubium and D. excisum in life‐table experiments in order to determine if their thermal performance curves (TPCs) explain their distribution and to estimate the extent and mode of genetic variation in their TPCs. Our results show that both species have higher optimum temperatures ( T o ∼ 33°C), critical thermal minimum (CT min = 10–15°C), and maximum (CT max = 39–40°C) than temperate cladocerans. Clones of D. excisum had narrower TPCs and higher T o than D. dubium clones, in accordance with predictions based on changes of temperature distributions with latitude. Significant levels of genetic variation in TPCs were present in both species. D. excisum had higher fitness than D. dubium at all temperatures above 15°C. However, at 15°C and below, D. dubium fitness was higher. Negative r at 15°C and below in combination with competition with the more cold‐adapted D. dubium exclude D. excisum from mainland China. TPCs of interacting species may be the basis of predicting future species distributions as temperature increases change the balance of biotic interactions.

A new dihydrochalcone glycoside from the stems of Homalium stenophyllum - Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Chang-Ri Han; Xiao-Ping Song (Natural Product Research, 2018)

PGL3 is required for chlorophyll synthesis and impacts leaf senescence in rice - Jing Ye; Yao-long Yang; Xing-hua Wei; Xiao-jun Niu; Shan Wang; Qun Xu; Xiao-ping Yuan; Han-yong Yu; Yi-ping Wang; Yue Feng; Shu Wang (Journal of Zhejiang University-SCIENCE B, 2018)

Overexpression of Nogo receptor 3 (NgR3) correlates with poor prognosis and contributes to the migration of epithelial cells of nasopharyngeal carcinoma patients - Jiang-Yi He; Ping Han; Yu Zhang; Yong-Dong Liu; Shi-Jian Song; Guo-Kai Feng; Yu An; Ai-Jun Zhou; Hong-Bo Wang; Li Yuan; Zhi-Rui Lin; Tian-Liang Xia; et al. (Journal of Molecular Medicine, 2018)

Species-based classification reveals spatial processes of phytoplankton meta-communities better than functional group approaches: a case study from three freshwater lake regions in China - Li-Juan Xiao; Yiqiu Zhu; Yang Yang; Qiuqi Lin; Bo-Ping Han; Judit Padisák (Hydrobiologia, 2018)

In type 2 diabetes induced by cigarette smoking, activation of p38 MAPK is involved in pancreatic β-cell apoptosis - Hui Xu; Qiushi Wang; Qian Sun; Yu Qin; Aohan Han; Ye Cao; Qianlei Yang; Ping Yang; Jiachun Lu; Qizhan Liu; Quanyong Xiang (Environmental Science and Pollution Research, 2018)

Effects of an additive (hydroxyapatite–biochar–zeolite) on the chemical speciation of Cd and As in paddy soils and their accumulation and translocation in rice plants - Jiao-Feng Gu; Hang Zhou; Wen-Tao Yang; Pei-Qin Peng; Ping Zhang; Min Zeng; Bo-Han Liao (Environmental Science and Pollution Research, 2018)

Spatial structure and β-diversity of phytoplankton in Tibetan Plateau lakes: nestedness or replacement? - Yang Yang; Ren Hu; Qiuqi Lin; Juzhi Hou; Yongqin Liu; Bo-Ping Han; Luigi Naselli-Flores (Hydrobiologia, 2018)

A new isoflavone from the roots of Ficus auriculata - Cui-Cui Qi; Yan-Hui Fu; Wen-Hao Chen; Guang-Ying Chen; Chun-Yan Dai; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2018)

AMPK/NF-κB signaling pathway regulated by ghrelin participates in the regulation of HUVEC and THP1 Inflammation - Min Zhang; Shuping Wang; Zhicheng Pan; Tiantong Ou; Jianwei Ma; Hua Liu; Ruogu Li; Ping Yang; Wenzheng Han; Shaofeng Guan; Xumin Hou; Weiyi Fang; et al. (Molecular and Cellular Biochemistry, 2018)

C21 steroid derivatives from the Dai herbal medicine Dai-Bai-Jie, the dried roots of Marsdenia tenacissima, and their screening for anti-HIV activity - Xu Pang; Li-Ping Kang; Xiao-Mei Fang; He-Shui Yu; Li-Feng Han; Yang Zhao; Li-Xia Zhang; Li-Yan Yu; Bai-Ping Ma (Journal of Natural Medicines, 2018)

Conserved peptides enhance immune efficiency of inactive vaccines against emerging avian influenza viruses in chicken - Jin Xiao; Lei Zhang; Zhenbao Wang; Wangzhen Xiang; Ping Lu; Yingze Zhao; Min Han; Airong Ma; Peng Qi; Ming Wang; George F. Gao; William J. Liu (Science China Life Sciences, 2017)

Comorbidity Burden of Dementia: A Hospital-Based Retrospective Study from 2003 to 2012 in Seven Cities in China - Qing-Hua Wang; Xin Wang; Xian-Le Bu; Yan Lian; Yang Xiang; Hong-Bo Luo; Hai-Qiang Zou; Jie Pu; Zhong-He Zhou; Xiao-Ping Cui; Qing-Song Wang; Xiang-Qun Shi; et al. (Neuroscience Bulletin, 2017)

Spatial heterogeneity and long-term dynamics of cladoceran ephippia in a monsoonal reservoir, driven by hydrology and eutrophication - Lei Xu; Shaolin Xu; Xiaoyu Han; Sijia Li; Henri J. Dumont; Bo-Ping Han (Journal of Paleolimnology, 2017)

Ammonia‐oxidising archaea living at low pH: Insights from comparative genomics - Craig W. Herbold; Laura E. Lehtovirta‐Morley; Man‐Young Jung; Nico Jehmlich; Bela Hausmann; Ping Han; Alexander Loy; Michael Pester; Luis A. Sayavedra‐Soto; Sung‐Keun Rhee; James I. Prosser; Graeme W. Nicol; et al. (Environmental Microbiology, 2017)
Summary Obligate acidophilic members of the thaumarchaeotal genus Candidatus Nitrosotalea play an important role in nitrification in acidic soils, but their evolutionary and physiological adaptations to acidic environments are still poorly understood, with only a single member of this genus ( Ca . N. devanaterra) having its genome sequenced. In this study, we sequenced the genomes of two additional cultured Ca . Nitrosotalea strains, extracted an almost complete Ca . Nitrosotalea metagenome‐assembled genome from an acidic fen, and performed comparative genomics of the four Ca . Nitrosotalea genomes with 19 other archaeal ammonia oxidiser genomes. Average nucleotide and amino acid identities revealed that the four Ca . Nitrosotalea strains represent separate species within the genus. The four Ca . Nitrosotalea genomes contained a core set of 103 orthologous gene families absent from all other ammonia‐oxidizing archaea and, for most of these gene families, expression could be demonstrated in laboratory culture or the environment via proteomic or metatranscriptomic analyses respectively. Phylogenetic analyses indicated that four of these core gene families were acquired by the Ca . Nitrosotalea common ancestor via horizontal gene transfer from acidophilic representatives of Euryarchaeota. We hypothesize that gene exchange with these acidophiles contributed to the competitive success of the Ca . Nitrosotalea lineage in acidic environments.

Ten years of elevated CO2 affects soil greenhouse gas fluxes in an open top chamber experiment - Jianfei Sun; Zongwei Xia; Tongxin He; Weiwei Dai; Bo Peng; Jun Liu; Decai Gao; Ping Jiang; Shijie Han; Edith Bai (Plant and Soil, 2017)

Molecular diversity of phenothiazines: design and synthesis of phenothiazine–dithiocarbamate hybrids as potential cell cycle blockers - Dong-Jun Fu; Ruo-Han Zhao; Jia-Huan Li; Jia-Jia Yang; Ruo-Wang Mao; Bo-Wen Wu; Ping Li; Xiao-Lin Zi; Qing-Qing Zhang; Hui-Jie Cai; Sai-Yang Zhang; Yan-Bing Zhang; et al. (Molecular Diversity, 2017)

Phospholipase D and phosphatidic acid mediate heat stress induced secondary metabolism in Ganoderma lucidum - Yong‐Nan Liu; Xiao‐Xiao Lu; Dai Chen; Ya‐Ping Lu; Ang Ren; Liang Shi; Jing Zhu; Ai‐Liang Jiang; Han‐Shou Yu; Ming‐Wen Zhao (Environmental Microbiology, 2017)
Summary Phospholipid‐mediated signal transduction plays a key role in responses to environmental changes, but little is known about the role of phospholipid signalling in microorganisms. Heat stress (HS) is one of the most important environmental factors. Our previous study found that HS could induce the biosynthesis of the secondary metabolites, ganoderic acids (GA). Here, we performed a comprehensive mass spectrometry‐based analysis to investigate HS‐induced lipid remodelling in Ganoderma lucidum . In particular, we observed a significant accumulation of phosphatidic acid (PA) on HS. Further genetic tests in which pld ‐silencing strains were constructed demonstrated that the accumulation of PA is dependent on HS‐activated phospholipase D (PLD) hydrolysing phosphatidylethanolamine. Furthermore, we determined the role of PLD and PA in HS‐induced secondary metabolism in G . lucidum . Exogenous 1‐butanol, which decreased PLD‐mediated formation of PA, reverses the increased GA biosynthesis that was elicited by HS. The pld ‐silenced strains partly blocked HS‐induced GA biosynthesis, and this block can be reversed by adding PA. Taken together, our results suggest that PLD and PA are involved in the regulation of HS‐induced secondary metabolism in G . lucidum . Our findings provide key insights into how microorganisms respond to heat stress and then consequently accumulate secondary metabolites by phospholipid remodelling.

A new catechin derivative from the fruits of Rosa sterilis S. D. Shi - Xu-Lu Luo; Han-Long Dan; Na Li; Yong-He Li; Ying-Jun Zhang; Ping Zhao (Natural Product Research, 2017)

Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents - Mei-Fang Gong; Rui-Ting Wen; Ying Xu; Jian-Chun Pan; Ning Fei; Yan-Meng Zhou; Jiang-Ping Xu; Jian-Hui Liang; Han-Ting Zhang (Psychopharmacology, 2017)

Kinetics of Antioxidant-Producing Maillard Reaction in the Mixture of Ribose and Sea Cucumber ( Stichopus japonicus ) Gut Hydrolysates - Jia-Run Han; Zhi-Mo Zhu; Hai-Tao Wu; Na Sun; Yue Tang; Cui-Ping Yu; Chen-Chen Zhao; Zheng-Yu Zhang; Ao-Ting Li; Jia-Nan Yan (Journal of Aquatic Food Product Technology, 2017)

Advances of genotyping-by-sequencing in fisheries and aquaculture - Yan-He Li; Han-Ping Wang (Reviews in Fish Biology and Fisheries, 2017)

Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells - Chun-Yu Liu; Kuen-Feng Chen; Tzu-I Chao; Pei-Yi Chu; Chun-Teng Huang; Tzu-Ting Huang; Hsiu-Ping Yang; Wan-Lun Wang; Chia-Han Lee; Ka-Yi Lau; Wen-Chun Tsai; Jung-Chen Su; et al. (Journal of Molecular Medicine, 2017)

Identifying functional groups and ecological roles of tropical and subtropical freshwater Cladocera in Asia - Eric Zeus C. Rizo; Yangliang Gu; Rey Donne S. Papa; Henri J. Dumont; Bo-Ping Han (Hydrobiologia, 2017)

Recognition model of groundwater inrush source of coal mine: a case study on Jiaozuo coal mine in China - Huang Ping-hua; Wang Xin-yi; Han Su-min (Arabian Journal of Geosciences, 2017)

A new norsesquiterpene from the roots of Polyalthia laui - Zhang-Xin Yu; Ming-Ye Zhuo; Xiao-Bao Li; Yan-Hui Fu; Guang-Ying Chen; Xiao-Ping Song; Chang-Ri Han; Xin-Ming Song; Qi-Jing Fan (Natural Product Research, 2017)

Fallow associated with autumn-plough favors structure stability and storage of soil organic carbon compared to continuous maize cropping in Mollisols - Shujie Miao; Yunfa Qiao; Ping Li; Xiaozeng Han; Caixian Tang (Plant and Soil, 2017)

Protein Misfolding Cyclic Amplification Cross-Species Products of Mouse-Adapted Scrapie Strain 139A and Hamster-Adapted Scrapie Strain 263K with Brain and Muscle Tissues of Opposite Animals Generate Infectious Prions - Chen Gao; Jun Han; Jin Zhang; Jing Wei; Bao-Yun Zhang; Chan Tian; Jie Zhang; Qi Shi; Xiao-Ping Dong (Molecular Neurobiology, 2017)

Increases of Galectin-1 and its S-nitrosylated form in the Brain Tissues of Scrapie-Infected Rodent Models and Human Prion Diseases - Yan-Jun Guo; Qi Shi; Xiao-Dong Yang; Jian-Le Li; Yue Ma; Kang Xiao; Cao Chen; Jun Han; Xiao-Ping Dong (Molecular Neurobiology, 2017)

Puerarin may protect against Schwann cell damage induced by glucose fluctuation - Bing Xue; Lin Wang; Zhe Zhang; Rui Wang; Xin-xin Xia; Ping-ping Han; Li-jun Cao; Yong-hui Liu; Lian-qing Sun (Journal of Natural Medicines, 2017)

Two ultraviolet radiation datasets that cover China - Hui Liu; Bo Hu; Yuesi Wang; Guangren Liu; Liqin Tang; Dongsheng Ji; Yongfei Bai; Weikai Bao; Xin Chen; Yunming Chen; Weixin Ding; Xiaozeng Han; et al. (Advances in Atmospheric Sciences, 2017)

One new lignan derivative from the Combretum alfredii Hance - Meng Bai; Li-Jun Wu; Yue Cai; Shou-Yuan Wu; Xiao-Ping Song; Guang-Ying Chen; Cai-Juan Zheng; Chang-Ri Han (Natural Product Research, 2017)

Work stress, family stress and asthma: a cross-sectional study among women in China - Adrian Loerbroks; Hui Ding; Wei Han; Hong Wang; Jiang-Ping Wu; Liu Yang; Peter Angerer; Jian Li (International Archives of Occupational and Environmental Health, 2017)

Genes Related to Oxytocin and Arginine-Vasopressin Pathways: Associations with Autism Spectrum Disorders - Rong Zhang; Hong-Feng Zhang; Ji-Sheng Han; Song-Ping Han (Neuroscience Bulletin, 2017)

A Volumetric and Functional Connectivity MRI Study of Brain Arginine-Vasopressin Pathways in Autistic Children - Xiao-Jing Shou; Xin-Jie Xu; Xiang-Zhu Zeng; Ying Liu; Hui-Shu Yuan; Yan Xing; Mei-Xiang Jia; Qing-Yun Wei; Song-Ping Han; Rong Zhang; Ji-Sheng Han (Neuroscience Bulletin, 2017)

Pyrimethanil sensitivity and fitness in Botrytis cinerea populations from Shanxi Province, China - Lu Ren; Xiao-jun Zhao; Xiao-jing Shi; Ping-yi Guo; Ju-cai Han (Journal of Plant Diseases and Protection, 2017)